mhurhangee/patent-ind-claim-en huggingface dataset:
An oral pharmaceutical composition comprising an oil-based liquid formulation, wherein said oil-based liquid formulation comprises a therapeutic protein of up to 100 kilodalton, a chelator of divalent cations, and an isolated BBI (Bowman-Birk inhibitor), and either; (i) said BBI has been purified to at least 85% purity, as measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), or (ii) said BBI has been purified to a protein content of greater than 95% by BCA (bicinchoninic acid) assay, or (iii) said BBI contains less than 0.1 % high-MW contaminants; wherein said liquid formulation has an antichymotrypsin activity of at least 40 mg. chymotrypsin inhibited per ml. of the liquid formulation; wherein said therapeutic protein is insulin or a GLP-1 (glucagon-like peptide-1) analogue. (i) said BBI has been purified to at least 85% purity, as measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE), or (ii) said BBI has been purified to a protein content of greater than 95% by BCA (bicinchoninic acid) assay, or (iii) said BBI contains less than 0.1 % high-MW contaminants; wherein said liquid formulation has an antichymotrypsin activity of at least 40 mg. chymotrypsin inhibited per ml. of the liquid formulation; wherein said therapeutic protein is insulin or a GLP-1 (glucagon-like peptide-1) analogue.
An analyzer for determining an indirect measurement of an airway pressure in a patient with a total liquid ventilation (TLV) system, comprising: - a measurement interface module for: (a) obtaining at least one pressure measurement of a liquid taken in the TLV system comprising an endotracheal tube having a distal end inserted in a patient's trachea, preferably said pressure measurement being taken at the proximal end of the endotracheal tube ; and (b) obtaining at least one flow measurement of a liquid taken in the TLV system; and - a processor module for: (c) considering a fluid model of the TLV system, processing the at least one pressure measurement and the at least one flow measurement into the indirect measurement of the airway pressure; wherein the processor module is configured to: - process the at least one flow measurement into a pressure drop value within the TLV system, preferably within the endotracheal tube , considering the fluid model of the TLV system; and - process the at least one pressure measurement and the pressure drop value into the indirect measurement of the airway pressure. - a measurement interface module for: (a) obtaining at least one pressure measurement of a liquid taken in the TLV system comprising an endotracheal tube having a distal end inserted in a patient's trachea, preferably said pressure measurement being taken at the proximal end of the endotracheal tube ; and (b) obtaining at least one flow measurement of a liquid taken in the TLV system; and (a) obtaining at least one pressure measurement of a liquid taken in the TLV system comprising an endotracheal tube having a distal end inserted in a patient's trachea, preferably said pressure measurement being taken at the proximal end of the endotracheal tube ; and (b) obtaining at least one flow measurement of a liquid taken in the TLV system; and - a processor module for: (c) considering a fluid model of the TLV system, processing the at least one pressure measurement and the at least one flow measurement into the indirect measurement of the airway pressure; - process the at least one flow measurement into a pressure drop value within the TLV system, preferably within the endotracheal tube , considering the fluid model of the TLV system; and - process the at least one pressure measurement and the pressure drop value into the indirect measurement of the airway pressure.
A method comprising: establishing an Ethernet Virtual Private Network, "EVPN", with a set of routers of a metro transport network positioned between at least one Internet service provider network and a set of customer devices, wherein the metro transport network provides layer two, "L2", packet switching for transporting network packets between the Internet service provider network and the customer devices, and wherein a first one of the routers is an access router coupled to the customer devices by an access link; receiving, with the access router, a packet from one of the customer devices by the access link; and responsive to receiving the packet, outputting by the access router, an EVPN MAC route advertisement that advertises an L2 network address of the packet as reachable through the access router, wherein the EVPN MAC route advertisement include a request to validate the L2 network address. establishing an Ethernet Virtual Private Network, "EVPN", with a set of routers of a metro transport network positioned between at least one Internet service provider network and a set of customer devices, wherein the metro transport network provides layer two, "L2", packet switching for transporting network packets between the Internet service provider network and the customer devices, and wherein a first one of the routers is an access router coupled to the customer devices by an access link; receiving, with the access router, a packet from one of the customer devices by the access link; and responsive to receiving the packet, outputting by the access router, an EVPN MAC route advertisement that advertises an L2 network address of the packet as reachable through the access router, wherein the EVPN MAC route advertisement include a request to validate the L2 network address.
A drive device for a movable furniture part , having a blocking element , a release element and a lockable ejection device , by means of which the movable furniture part can be ejected from a closed position by a force accumulator in the opening direction, wherein the ejection device is unlockable by overpressing the movable furniture part from the locked closed position in the closing direction, and an overpressing safeguard is provided, which prevents unlocking of the ejection device from occurring in the event of a closing procedure and a movement of the movable furniture part beyond the closed position into the overpressing position, wherein the ejection device is unlockable via a control element , which is movable with the movable furniture part from a closed position into the overpressing position, wherein the blocking element , in a first position, blocks a movement of the control element into the actuating position and, in a second position, releases the access for the control element to the actuating position, wherein upon a continuous movement of the movable furniture part in the closing direction into the closed position and beyond the closed position into the overpressing position, for an overpressing safeguard, the blocking element is moved into the first position, and then is movable via the release element into the second position, characterized in that the release element comprises a damper formed as a linear damper or rotation damper, which is pre-tensioned by a spring in a starting position or comprises a mechanical timing element, which decelerates the movement of the blocking element from the first into the second position.
An antenna array comprising several loops as well as several antenna elements , wherein the several antenna elements are arranged in a circular array, wherein the several loops are located within the circular array established by the several antenna elements , wherein the several loops are established by a common base part , a common cover part and joint elements , wherein the number of joint elements is an integer multiple or an integer fraction of the number of antenna elements , and wherein each of the antenna elements is capacitively coupled with a respective loop of the several loops , characterized in that the joint elements comprise terminal ports configured for coupling signal voltages.
A method in a wireless device for reference transmission point, TP, selection, the method comprising: receiving assistance information from a first node, the assistance information comprising data associated with a first reference TP, the first reference TP located in a cell having two or more TPs, wherein the first reference TP has the same physical cell ID as the two or more TPs in the cell; and calculating a first reference signal time difference, RSTD, measurement using the data associated with a first reference TP; determining that the first reference TP does not provide an acceptable RSTD measurement; selecting a second reference TP different from the first reference TP; and calculating a second RSTD measurement from the second reference TP. receiving assistance information from a first node, the assistance information comprising data associated with a first reference TP, the first reference TP located in a cell having two or more TPs, wherein the first reference TP has the same physical cell ID as the two or more TPs in the cell; and calculating a first reference signal time difference, RSTD, measurement using the data associated with a first reference TP; determining that the first reference TP does not provide an acceptable RSTD measurement; selecting a second reference TP different from the first reference TP; and calculating a second RSTD measurement from the second reference TP.
A composition comprising: a) one or more isocyanate functional components; b) one or more alkoxyalkyl benzoates; and c) one or more catalysts for the reaction of isocyanate moieties with hydroxyl groups.
An arc welding control method of performing arc welding, characterized in that a welding wire that is a consumable electrode is fed by alternately repeating forward feeding that feeds the welding wire toward a welding subject and reverse feeding that feeds the welding wire in a direction opposite to the forward feeding at a predetermined period and amplitude in a periodical manner, and a first heat input period having a first heat input amount and a second heat input period having a second heat input amount that is less than the first heat input amount are periodically repeated, wherein each of the first heat input period and the second heat input period includes a short-circuit period and an arc period, and when release of short-circuit of the welding wire is detected during the short-circuit period in the second heat input period, an arc is extinguished.
A fluid discharge event detection apparatus, comprising: a first conduit ; a sensing conduit ; a control valve , coupled between the first conduit and the sensing conduit , configured to activate and fluidly couple the first conduit and the sensing conduit to one another when the control valve detects at least one predetermined condition of a fluid within the first conduit; a sensor , disposed and positioned about the sensing conduit and entirely outside of an interior of the sensing conduit , configured to generate a sensor output signal; and a controller , coupled to the sensor , configured to periodically: measure a capacitance value of the sensing conduit as a function of the sensor output signal; detect a change in the measured sensing conduit capacitance value; and assert an alarm condition upon detection of the change in the measured sensing conduit capacitance value, wherein the controller is further configured to: detect a rate of change of the measured capacitance value of the sensing conduit ; and distinguish between an excess temperature condition and an excess pressure condition as a function of the detected rate of change of the measured capacitance value of the sensing conduit . a first conduit ; a sensing conduit ; a control valve , coupled between the first conduit and the sensing conduit , configured to activate and fluidly couple the first conduit and the sensing conduit to one another when the control valve detects at least one predetermined condition of a fluid within the first conduit; a sensor , disposed and positioned about the sensing conduit and entirely outside of an interior of the sensing conduit , configured to generate a sensor output signal; and a controller , coupled to the sensor , configured to periodically: measure a capacitance value of the sensing conduit as a function of the sensor output signal; detect a change in the measured sensing conduit capacitance value; and assert an alarm condition upon detection of the change in the measured sensing conduit capacitance value, measure a capacitance value of the sensing conduit as a function of the sensor output signal; detect a change in the measured sensing conduit capacitance value; and assert an alarm condition upon detection of the change in the measured sensing conduit capacitance value, wherein the controller is further configured to: detect a rate of change of the measured capacitance value of the sensing conduit ; and distinguish between an excess temperature condition and an excess pressure condition as a function of the detected rate of change of the measured capacitance value of the sensing conduit . detect a rate of change of the measured capacitance value of the sensing conduit ; and distinguish between an excess temperature condition and an excess pressure condition as a function of the detected rate of change of the measured capacitance value of the sensing conduit .
An elastic band ligation device , including a body , an inner tube , a deployer , and a grasper , the grasper including at least two gripping arms, the grasper being slidably mounted within the inner tube, so that movement of the grasper relative to the inner tube causes the gripping arms to open and close, the arrangement being such that when the gripping arms are in a closed position, and operatively retaining a haemorrhoid, the gripping arms are within the inner tube, and the deployer is positioned to release a band around the haemorrhoid characterised in that movement of the deployer with respect to the body is controlled using a ratchet mechanism including ratchet teeth on the body that are engaged by corresponding ratchet teeth on the deployer wherein angles on the ratchet teeth are such that movement of the deployer is one-way to force the band to be dispensed from a tip, wherein a button is supported by a resilient structure moulded into the body, wherein when the button is depressed, the deployer flexes, causing the ratchet teeth on the deployer to walk relative to the ratchet teeth on the body, and when the button is released the resilient structure pushes the button back and ratchet teeth on the deployer walk over ratchet teeth on the body to thereby pull the deployer forward and into the next incremental position relative to the body wherein pressing the button again will deploy a further band. deployer , and a grasper , the grasper including at least two gripping arms, the grasper being slidably mounted within the inner tube, so that movement of the grasper relative to the inner tube causes the gripping arms to open and close, the arrangement being such that when the gripping arms are in a closed position, and operatively retaining a haemorrhoid, the gripping arms are within the inner tube, and the deployer is positioned to release a band around the haemorrhoid characterised in that movement of the deployer with respect to the body is controlled using a ratchet mechanism including ratchet teeth on the body that are engaged by corresponding ratchet teeth on the deployer wherein angles on the ratchet teeth are such that movement of the deployer is one-way to force the band to be dispensed from a tip, wherein a button is supported by a resilient structure moulded into the body, wherein when the button is depressed, the deployer flexes, causing the ratchet teeth on the deployer to walk relative to the ratchet teeth on the body, and when the button is released the resilient structure pushes the button back and ratchet teeth on the deployer walk over ratchet teeth on the body to thereby pull the deployer forward and into the next incremental position relative to the body wherein pressing the button again will deploy a further band.
Pipe connector for connecting at least two pipes used in kitchen construction, wherein the pipe connector has a first receptacle with a first insertion opening for inserting a pipe and a second receptacle with a second insertion opening for inserting a pipe , wherein the pipe connector has at least one, preferably circumferential, stop which is arranged between the first and the second insertion opening on an inner side of the pipe connector and which defines a maximum insertion depth of a pipe into the first and/or second receptacle , wherein the pipe connector has at least one, preferably circumferential, sealing lip which is arranged on the inner side of the pipe connector between the first or the second insertion opening and the stop , characterized in that the pipe connector has a flexible region which is arranged between the first and the second insertion opening and which is composed of a deformable, compressible or expandable and/or elastic material, with the result that the first receptacle can be displaced translationally and/or rotationally relative to the second receptacle , wherein the flexible region has or is a bellows at least in sections.
A mount, comprising: a locating pin ; a load pin ; and a fastener , the fastener configured to retain a component on at least one of the locating pin and the load pin, the fastener including a bolt configured to engage an engine case or fan case to mount the component with respect to the engine case or fan case, a mounting boss and a spring , the spring allowing the mounting boss to move with respect to the bolt, and characterized in that the bolt is held captive in the mounting boss with a captive feature , the captive feature holding the bolt, the mounting boss and the spring together; and wherein the captive feature includes a resilient c-ring on the bolt, and wherein the resilient c-ring is configured to interact with a neck on the mounting boss. a locating pin ; a load pin ; and a fastener , the fastener configured to retain a component on at least one of the locating pin and the load pin, the fastener including a bolt configured to engage an engine case or fan case to mount the component with respect to the engine case or fan case, a mounting boss and a spring , the spring allowing the mounting boss to move with respect to the bolt, and characterized in that the bolt is held captive in the mounting boss with a captive feature , the captive feature holding the bolt, the mounting boss and the spring together; and wherein the captive feature includes a resilient c-ring on the bolt, and wherein the resilient c-ring is configured to interact with a neck on the mounting boss.
Battery exchange system for an electric vehicle , comprising: - a battery unit comprising a bottom surface , a top surface and a circumferential side surface extending therebetween; - a battery receiving unit adapted for being fixed at or near an underside of the electric vehicle and comprising a housing with an opening at a bottom side of the housing for at least partially receiving the battery unit in the housing through the opening, wherein the battery receiving unit has a central axis (C) which extends through the opening; wherein the battery receiving unit is adapted for allowing movement of the battery unit along the central axis (C) between an unmounted position below the battery receiving unit and a mounted position at least partially within the battery receiving unit, characterized in that the battery unit comprises first engagement elements and the battery receiving unit comprises second engagement elements , each of the first and second engagement elements being adapted for engaging each other while moving relative to each other along an associated sloping path (S1; S7 - S10; S11 - S14; S15 - S17) causing lifting of the battery unit from the unmounted position to the mounted position or lowering of the battery unit from the mounted position to the unmounted position, wherein said associated sloping path slopes with respect to a plane normal to the central axis (C). - a battery unit comprising a bottom surface , a top surface and a circumferential side surface extending therebetween; - a battery receiving unit adapted for being fixed at or near an underside of the electric vehicle and comprising a housing with an opening at a bottom side of the housing for at least partially receiving the battery unit in the housing through the opening, wherein the battery receiving unit has a central axis (C) which extends through the opening; wherein the battery receiving unit is adapted for allowing movement of the battery unit along the central axis (C) between an unmounted position below the battery receiving unit and a mounted position at least partially within the battery receiving unit, characterized in that the battery unit comprises first engagement elements and the battery receiving unit comprises second engagement elements , each of the first and second engagement elements being adapted for engaging each other while moving relative to each other along an associated sloping path (S1; S7 - S10; S11 - S14; S15 - S17) causing lifting of the battery unit from the unmounted position to the mounted position or lowering of the battery unit from the mounted position to the unmounted position, wherein said associated sloping path slopes with respect to a plane normal to the central axis (C).
A pharmaceutical composition for injection comprising a substantially stable dispersion of solid nanoparticles in an aqueous medium, wherein the solid nanoparticles comprise a microtubule inhibitor and have a mean particle size of less than 220 nm, wherein the composition is prepared by a process comprising: (a) combining an aqueous phase comprising water and an emulsifier and an organic phase comprising the microtubule inhibitor, a water-immiscible organic solvent, optionally a water-miscible organic solvent as an interfacial lubricant and at least one Ostwald ripening inhibitor; (b) forming an oil-in-water emulsion using a high pressure homogenizer; and (c) removing the water-immiscible organic solvent and the water-miscible organic solvent from the oil-in water emulsion under vacuum; thereby forming a substantially stable dispersion of solid nanoparticles comprising the Ostwald ripening inhibitor, the emulsifier and the microtubule inhibitor in the aqueous medium; wherein the Ostwald ripening inhibitor comprises cholesterol and a member selected from the group consisting of cholesteryl stearate, hexadecyl hexadecanoate, glyceryl tristearate, and combinations thereof; wherein the microtubule inhibitor is a taxane;and wherein the emulsifier is albumin. (a) combining an aqueous phase comprising water and an emulsifier and an organic phase comprising the microtubule inhibitor, a water-immiscible organic solvent, optionally a water-miscible organic solvent as an interfacial lubricant and at least one Ostwald ripening inhibitor; (b) forming an oil-in-water emulsion using a high pressure homogenizer; and (c) removing the water-immiscible organic solvent and the water-miscible organic solvent from the oil-in water emulsion under vacuum;
A vehicle safety system, especially an airbag module, comprising: an airbag , a retaining plate for retaining the airbag , an inflator comprising an inflator flange , a damper having at least one damper base , a free end of the damper base being adapted to be mounted on the inflator flange , especially to be clipped into the inflator flange , and an inflator support , wherein the free end of the damper base points away from the airbag and/or from the retaining plate , characterized in that the damper is clamped between the retaining plate and the inflator support . an airbag , a retaining plate for retaining the airbag , an inflator comprising an inflator flange , a damper having at least one damper base , a free end of the damper base being adapted to be mounted on the inflator flange , especially to be clipped into the inflator flange , and an inflator support , wherein the free end of the damper base points away from the airbag and/or from the retaining plate , characterized in that the damper is clamped between the retaining plate and the inflator support .