mhurhangee/patent-ind-claim-en huggingface dataset:
A copper/ceramic bonded body comprising: a copper member made of copper or a copper alloy; and a ceramic member made of nitrogen-containing ceramics, the copper member and the ceramic member being bonded to each other, wherein, between the copper member and the ceramic member, an active metal nitride layer containing nitrides of one or more active metals selected from Ti, Zr, Nb, and Hf is formed on a ceramic member side, and a Mg solid solution layer in which Mg is solid-dissolved in a Cu matrix is formed between the active metal nitride layer and the copper member, Cu-containing particles composed of either one or both of Cu particles and compound particles of Cu and the active metal are dispersed in an interior of the active metal nitride layer, a ratio C2/C1 of an average copper concentration C1 (atomic%) in a region from an interface on a ceramic member side to a position of 25% of a total thickness of the active metal nitride layer to an average copper concentration C2 (atomic%) in a region from an interface on a copper member side to a position of 25% of the total thickness of the active metal nitride layer is 0.8 or less, and the ratio C2/C1 is determined in accordance with the description. a copper member made of copper or a copper alloy; and a ceramic member made of nitrogen-containing ceramics, the copper member and the ceramic member being bonded to each other, wherein, between the copper member and the ceramic member, an active metal nitride layer containing nitrides of one or more active metals selected from Ti, Zr, Nb, and Hf is formed on a ceramic member side, and a Mg solid solution layer in which Mg is solid-dissolved in a Cu matrix is formed between the active metal nitride layer and the copper member, Cu-containing particles composed of either one or both of Cu particles and compound particles of Cu and the active metal are dispersed in an interior of the active metal nitride layer, a ratio C2/C1 of an average copper concentration C1 (atomic%) in a region from an interface on a ceramic member side to a position of 25% of a total thickness of the active metal nitride layer to an average copper concentration C2 (atomic%) in a region from an interface on a copper member side to a position of 25% of the total thickness of the active metal nitride layer is 0.8 or less, and the ratio C2/C1 is determined in accordance with the description.
A pharmaceutical composition comprising at least 150 mg and up to 750 mg Ceritinib and more than 40 and up to 70 weight percent of Ceritinib based on the total weight of the pharmaceutical composition, wherein the composition comprises granules consisting of or substantially consisting of Ceritinib and polyvinylpyrrolidone and the granules are obtainable by wet granulation.
An implantable medical device system , comprising: a sensing circuit configured to sense a first cardiac electrical signal via a first sensing electrode vector; a therapy delivery circuit configured to generate pacing pulses; and a control circuit configured to determine a type of cardiac capture evoked by a first pacing pulse generated by the therapy delivery circuit by: detecting from the first cardiac electrical signal a QRS signal following the first pacing pulse; determining a time interval from the first pacing pulse to the QRS signal; determining that the time interval from the first pacing pulse to the QRS signal is greater than a first threshold time interval and less than a second threshold time interval; and determining the type of cardiac capture to be selective His bundle capture of the ventricular conduction system based on the determined time interval being greater than the first threshold time interval and less than the second threshold time interval. a sensing circuit configured to sense a first cardiac electrical signal via a first sensing electrode vector; a therapy delivery circuit configured to generate pacing pulses; and a control circuit configured to determine a type of cardiac capture evoked by a first pacing pulse generated by the therapy delivery circuit by: detecting from the first cardiac electrical signal a QRS signal following the first pacing pulse; determining a time interval from the first pacing pulse to the QRS signal; determining that the time interval from the first pacing pulse to the QRS signal is greater than a first threshold time interval and less than a second threshold time interval; and determining the type of cardiac capture to be selective His bundle capture of the ventricular conduction system based on the determined time interval being greater than the first threshold time interval and less than the second threshold time interval. detecting from the first cardiac electrical signal a QRS signal following the first pacing pulse; determining a time interval from the first pacing pulse to the QRS signal; determining that the time interval from the first pacing pulse to the QRS signal is greater than a first threshold time interval and less than a second threshold time interval; and determining the type of cardiac capture to be selective His bundle capture of the ventricular conduction system based on the determined time interval being greater than the first threshold time interval and less than the second threshold time interval.
A method of detecting a LADAR signal, the method comprising: transmitting a laser signal from a platform , wherein the laser signal has a transmitter center wavelength and a transmitter linewidth ; returning the laser signal from a target that is moving relative to the platform with a target velocity by directing the laser signal toward the target, wherein the target velocity is a relative velocity of the target relative to the platform in a direction between the platform and the target, and wherein the laser signal returned from the target has a return center wavelength that is offset relative to the transmitter center wavelength by a Doppler offset due to the target velocity; adjusting a dynamic receiver filter to a receiver center wavelength that is based upon an expected return center wavelength , wherein the adjusting includes performing at least one of measuring, estimating, or determining the relative target velocity based upon at least one of measuring, estimating, or determining a velocity of the platform for determining the expected return center wavelength ; filtering the laser signal returned from the target with the dynamic receiver filter to reject ambient light mingled with the laser signal returned from the target and to produce a filtered laser signal; and detecting the filtered laser signal to determine a distance between the platform and the target. transmitting a laser signal from a platform , wherein the laser signal has a transmitter center wavelength and a transmitter linewidth ; returning the laser signal from a target that is moving relative to the platform with a target velocity by directing the laser signal toward the target, wherein the target velocity is a relative velocity of the target relative to the platform in a direction between the platform and the target, and wherein the laser signal returned from the target has a return center wavelength that is offset relative to the transmitter center wavelength by a Doppler offset due to the target velocity; adjusting a dynamic receiver filter to a receiver center wavelength that is based upon an expected return center wavelength , wherein the adjusting includes performing at least one of measuring, estimating, or determining the relative target velocity based upon at least one of measuring, estimating, or determining a velocity of the platform for determining the expected return center wavelength ; filtering the laser signal returned from the target with the dynamic receiver filter to reject ambient light mingled with the laser signal returned from the target and to produce a filtered laser signal; and detecting the filtered laser signal to determine a distance between the platform and the target.
A multiple-metal salt assembly of dendrimer, wherein four or more types of multiple-metal salt compounds with multiple metal species are assembled for each of parts with different environments in dendrimer whose core is a group expressed by a following Formula (I): [Chem. 1] ―(X) n C (Ph) 4―n ― (I) (in which n number of Xs independently represent a divalent group corresponding to a residue of a six-membered ring aromatic heterocyclic compound including, as a hetero atom, at least one selected from nitrogen, phosphorus, and arsenic, a derivative thereof, or a benzene derivative including an electron-donating functional group, Ph represents a phenylene group, and n represents an integer of 1 to 3).
An assembly in a turbine comprising: - at least one turbine ring made of ceramic material composite with a matrix and silicon carbide SiC fibres, the ring including a plurality of sectors , arranged circumferentially end-to-end, each of the ring sectors comprises at least one circumferential edge provided with at least one slot opening out circumferentially, - at least one sealing member 60 being inserted for a first portion into one of said slots of an edge of a first ring sector and for a second portion into one of said slots of an edge of a second ring sector, circumferentially adjacent to the first ring sector, the assembly being characterised in that the sealing member 60 is made of composite material with a ceramic matrix with a matrix and oxide fibres. - at least one turbine ring made of ceramic material composite with a matrix and silicon carbide SiC fibres, the ring including a plurality of sectors , arranged circumferentially end-to-end, each of the ring sectors comprises at least one circumferential edge provided with at least one slot opening out circumferentially, - at least one sealing member 60 being inserted for a first portion into one of said slots of an edge of a first ring sector and for a second portion into one of said slots of an edge of a second ring sector, circumferentially adjacent to the first ring sector,
A method for the screening, diagnosis and/or monitoring of subclinical atherosclerosis, preferably generalized subclinical atherosclerosis, in a subject, wherein said method comprises: a) determining in a biological sample isolated from said subject the protein expression levels of: i. PIGR and/or IGHA2; and ii. optionally, one, two, three, four or five biomarkers, selected from APOA, HPT, HEP2, ITIH1 and C5; b) comparing the levels of the biomarkers with a reference value; c) wherein when the levels in the subject's sample of PIGR and/or IGHA2, and optionally APOA, HPT, HEP2, ITIH1 and/or C5, are increased with respect to the corresponding reference value is indicative of subclinical atherosclerosis. a) determining in a biological sample isolated from said subject the protein expression levels of: i. PIGR and/or IGHA2; and ii. optionally, one, two, three, four or five biomarkers, selected from APOA, HPT, HEP2, ITIH1 and C5; i. PIGR and/or IGHA2; and ii. optionally, one, two, three, four or five biomarkers, selected from APOA, HPT, HEP2, ITIH1 and C5; b) comparing the levels of the biomarkers with a reference value; c) wherein when the levels in the subject's sample of PIGR and/or IGHA2, and optionally APOA, HPT, HEP2, ITIH1 and/or C5, are increased with respect to the corresponding reference value is indicative of subclinical atherosclerosis.
A dunnage conversion system , comprising: a supply of sheet stock material including a sheet stock material having a plurality of slits configured to expand under tension applied in a feed direction ; and a conversion machine including a converging chute downstream of the supply that converges in a feed direction from a relatively wider upstream end to a relatively narrower downstream end to randomly crumple the sheet stock material passing therethrough, feed wheels downstream of the converging chute , the feed wheels being driven to advance the sheet stock material in the feed direction , and pinch rollers disposed between the feed wheels and the supply, the pinch rollers being rotatable, where the feed wheels and the pinch rollers cooperate to apply tension in the feed direction to the sheet stock material traveling therebetween to expand the sheet stock material . a supply of sheet stock material including a sheet stock material having a plurality of slits configured to expand under tension applied in a feed direction ; and a conversion machine including a converging chute downstream of the supply that converges in a feed direction from a relatively wider upstream end to a relatively narrower downstream end to randomly crumple the sheet stock material passing therethrough, feed wheels downstream of the converging chute , the feed wheels being driven to advance the sheet stock material in the feed direction , and pinch rollers disposed between the feed wheels and the supply, the pinch rollers being rotatable, where the feed wheels and the pinch rollers cooperate to apply tension in the feed direction to the sheet stock material traveling therebetween to expand the sheet stock material . a converging chute downstream of the supply that converges in a feed direction from a relatively wider upstream end to a relatively narrower downstream end to randomly crumple the sheet stock material passing therethrough, feed wheels downstream of the converging chute , the feed wheels being driven to advance the sheet stock material in the feed direction , and pinch rollers disposed between the feed wheels and the supply, the pinch rollers being rotatable, where the feed wheels and the pinch rollers cooperate to apply tension in the feed direction to the sheet stock material traveling therebetween to expand the sheet stock material .
Transport apparatus (30; 300) for transporting output tools on the human body or on a tool , having at least one receiving device for receiving a predetermined output tool for a tool , wherein precisely one predetermined output tool is provided for each receiving device in that no output tool other than the one predetermined output tool can be plugged into a slot of a receiving device , and a communication device (32; 320) which is configured to transmit a signal containing information relating to the predetermined output tool to the tool (10; 100), wherein the information is data, for which different screwing programs are stored in the tool (10; 100), and wherein the at least one screwing program is possible for handling one or more workpieces using the output tool which has been removed from the receiving device , and wherein the communication device is configured to transmit the signal to the tool (10; 100) when a predetermined output tool is removed from at least one receiving device . at least one receiving device for receiving a predetermined output tool for a tool , wherein precisely one predetermined output tool is provided for each receiving device in that no output tool other than the one predetermined output tool can be plugged into a slot of a receiving device , and a communication device (32; 320) which is configured to transmit a signal containing information relating to the predetermined output tool to the tool (10; 100), wherein the information is data, for which different screwing programs are stored in the tool (10; 100), and wherein the at least one screwing program is possible for handling one or more workpieces using the output tool which has been removed from the receiving device , and wherein the communication device is configured to transmit the signal to the tool (10; 100) when a predetermined output tool is removed from at least one receiving device .
Driverless transporter , which comprises an undercarriage , a drive and a control unit, for transporting goods, in particular for loading a transfer station with one or a plurality of workpieces, wherein the driverless transporter comprises a handling arrangement with a telescopic extension for moving the transported goods in a horizontal direction, characterized in that the driverless transporter comprises coupling unit for mechanically coupling the transporter to a transfer station .
Association of tulathromycin and a compound of formula I for the use thereof in the treatment, the metaphylaxis or the prevention of a microbial infection, the compound meets the following formula I: wherein R 1 , R 2 , R 3 each represent, independently of each other, H, OH, a (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 1 -C 6 ) halogenoalkyl, (C 1 -C 6 ) alkoxy, (C 2 -C 6 ) alkenoxy, (C 1 -C 6 ) halogenoalkoxy, -O-CO-(C 1 -C 6 ) alkyl group; A represents a heteroatom or a -(Het)-R' or R-(Het)-R' group where R, R' each represent, independently of each other, a (C 1 -C 4 ) alkanediyl group optionally substituted by C 1 -C 4 alkyl radicals and Het represents a heteroatom; in a weight ratio, compound of formula (I) : tulathromycin, varying from 8 :1 to 1 :10, and in that the microbial infection is induced notably by a strain A pathogen and that on this strain A, the concentration of compound (I) meets the following equation: [C] < [MIC] / x Where [C] is the concentration according to the invention of compound (I) to use on the strain A [MIC] is the measured MIC for the compound (I), alone, on this strain A x is greater than or equal to 100, advantageously 1,000, more advantageously x is comprised between 2,000 and 10,000, or even greater than 50,000. R 1 , R 2 , R 3 each represent, independently of each other, H, OH, a (C 1 -C 6 ) alkyl, (C 2 -C 6 ) alkenyl, (C 1 -C 6 ) halogenoalkyl, (C 1 -C 6 ) alkoxy, (C 2 -C 6 ) alkenoxy, (C 1 -C 6 ) halogenoalkoxy, -O-CO-(C 1 -C 6 ) alkyl group; A represents a heteroatom or a -(Het)-R' or R-(Het)-R' group where R, R' each represent, independently of each other, a (C 1 -C 4 ) alkanediyl group optionally substituted by C 1 -C 4 alkyl radicals and Het represents a heteroatom; in a weight ratio, compound of formula (I) : tulathromycin, varying from 8 :1 to 1 :10, and in that the microbial infection is induced notably by a strain A pathogen and that on this strain A, the concentration of compound (I) meets the following equation: [C] < [MIC] / x Where [C] is the concentration according to the invention of compound (I) to use on the strain A [MIC] is the measured MIC for the compound (I), alone, on this strain A x is greater than or equal to 100, advantageously 1,000, more advantageously x is comprised between 2,000 and 10,000, or even greater than 50,000. Where [C] is the concentration according to the invention of compound (I) to use on the strain A [MIC] is the measured MIC for the compound (I), alone, on this strain A x is greater than or equal to 100, advantageously 1,000, more advantageously x is comprised between 2,000 and 10,000, or even greater than 50,000.
A circuit for starting an air conditioner, comprising: a DC power supply , is configured to supply a DC power to an controller which is a main chip of an air conditioner outdoor unit; a communication line , which is connected between the air conditioner outdoor unit and an air conditioner indoor unit; a main chip of the air conditioner indoor unit, which is configured to outputs a control signal when the air conditioner indoor unit is powered on by an indoor and outdoor unit connecting line, and the DC power supply is connected to the communication line under an action of the control signal, and the DC power supply supplies DC power to the controller through the communication line ; the controller , which is configured to generate a start triggering signal when the DC power supply supplies DC power to the controller through the communication line ; and a switch circuit , switching on, triggered by the start triggering signal, a power supply loop between an AC power supply and the air conditioner outdoor unit to start the air conditioner outdoor unit, wherein the AC power supply is disposed on the air conditioner outdoor unit. a DC power supply , is configured to supply a DC power to an controller which is a main chip of an air conditioner outdoor unit; a communication line , which is connected between the air conditioner outdoor unit and an air conditioner indoor unit; a main chip of the air conditioner indoor unit, which is configured to outputs a control signal when the air conditioner indoor unit is powered on by an indoor and outdoor unit connecting line, and the DC power supply is connected to the communication line under an action of the control signal, and the DC power supply supplies DC power to the controller through the communication line ; the controller , which is configured to generate a start triggering signal when the DC power supply supplies DC power to the controller through the communication line ; and a switch circuit , switching on, triggered by the start triggering signal, a power supply loop between an AC power supply and the air conditioner outdoor unit to start the air conditioner outdoor unit, wherein the AC power supply is disposed on the air conditioner outdoor unit.
A method for filtering a protein-containing liquid containing protein at a concentration of 20 mg/mL or more and 100 mg/mL or less, the method comprising a prefiltration step of filtering the protein-containing liquid by a prefilter having a pore size, determined as described in the description, of 0.08 μm to 0.25 μm and comprising a hydrophobic resin, and a virus removal step of filtering the protein-containing liquid by a virus removal membrane comprising a synthetic polymer, after the prefiltration step, wherein the protein-containing liquid before conducting the prefiltration step comprises, determined as described in the description, 0.25 g or more of a trimer or higher multimer of the proteins having an average diameter of less than 100 nm, per 1 m 2 of the virus removal membrane, wherein the prefilter comprises a material selected from the group consisting of a polyamide resin, a polysulfone-based resin and a fluororesin, wherein the virus removal membrane comprises polyvinylidene fluoride, wherein the hydrophobic resin hydrophobically interacts with and adsorbs the trimers or higher multimers of the proteins, wherein the virus removal membrane has hydrophilic graft chains by a graft polymerization method, and wherein the logarithmic removal rate (LRV) for parvovirus by the virus removal membrane, determined as described in the description, is 4.0 or more. a prefiltration step of filtering the protein-containing liquid by a prefilter having a pore size, determined as described in the description, of 0.08 μm to 0.25 μm and comprising a hydrophobic resin, and a virus removal step of filtering the protein-containing liquid by a virus removal membrane comprising a synthetic polymer, after the prefiltration step, wherein the protein-containing liquid before conducting the prefiltration step comprises, determined as described in the description, 0.25 g or more of a trimer or higher multimer of the proteins having an average diameter of less than 100 nm, per 1 m 2 of the virus removal membrane, wherein the prefilter comprises a material selected from the group consisting of a polyamide resin, a polysulfone-based resin and a fluororesin, wherein the virus removal membrane comprises polyvinylidene fluoride, wherein the hydrophobic resin hydrophobically interacts with and adsorbs the trimers or higher multimers of the proteins, wherein the virus removal membrane has hydrophilic graft chains by a graft polymerization method, and wherein the logarithmic removal rate (LRV) for parvovirus by the virus removal membrane, determined as described in the description, is 4.0 or more.