mhurhangee/patent-ind-claim-en huggingface dataset:
A method of predicting a likelihood that a cancer patient will respond positively to immunotherapy, the method comprising: (A) scoring a sample comprising tumor tissue previously taken from the cancer patient comprising: using the sample comprising tumor tissue taken from the cancer patient, determining an interaction score representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing PD-1 and a second member of the at least one pair of cells expressing PD-L1; and recording the interaction score; (B) deriving a value for % biomarker positivity (PBP) for all HLA-DR positive cells in a field of view of the sample expressing HLA-DR + IDO-1 + , and recording the value for PBP; and (C) comparing the interaction score to a first threshold value and comparing the value for PBP to a second threshold value; wherein if either the interaction score is greater than or equal to the first threshold value or the value for PBP is greater than or equal to the second threshold value, or the interaction score is greater than or equal to the first threshold value and the value for PBP is greater than or equal to the second threshold value, then the cancer patient is likely to respond positively to immunotherapy. (A) scoring a sample comprising tumor tissue previously taken from the cancer patient comprising: using the sample comprising tumor tissue taken from the cancer patient, determining an interaction score representative of a spatial proximity between at least one pair of cells, a first member of the at least one pair of cells expressing PD-1 and a second member of the at least one pair of cells expressing PD-L1; and recording the interaction score; (B) deriving a value for % biomarker positivity (PBP) for all HLA-DR positive cells in a field of view of the sample expressing HLA-DR + IDO-1 + , and recording the value for PBP; and (C) comparing the interaction score to a first threshold value and comparing the value for PBP to a second threshold value;
A decorative laminate film including at least an inner film and an outer film and having a character and/or a figure at least a part of which is formed as a protruded portion protruding toward the outer film, wherein: the inner film of the laminate film includes polyethylene or polypropylene, and the outer film includes stretched nylon or stretched polyethylene terephthalate; between the inner film and the outer film, the decorative laminate film has a print layer including a high-brightness ink and/or a foamed film having a pearly luster; at least a part of the character and/or the figure has a metallic luster derived from the print layer including the high-brightness ink or a pearly luster derived from the foamed film, the character and/or the figure is different from at least a part of a remaining region in at least one of hue, brightness, chroma and gloss, and the protruded portion is formed along at least a part of the character and/or the figure. the inner film of the laminate film includes polyethylene or polypropylene, and the outer film includes stretched nylon or stretched polyethylene terephthalate; between the inner film and the outer film, the decorative laminate film has a print layer including a high-brightness ink and/or a foamed film having a pearly luster; at least a part of the character and/or the figure has a metallic luster derived from the print layer including the high-brightness ink or a pearly luster derived from the foamed film, the character and/or the figure is different from at least a part of a remaining region in at least one of hue, brightness, chroma and gloss, and the protruded portion is formed along at least a part of the character and/or the figure.
A liquid composition C for use in the cleavage of a di(p-methoxyphenyl)phenylmethyl protecting group from a hydroxyl group, the composition comprising an aprotic solvent, at least one alcohol selected from the group consisting of trifluoroethanol, hexafluoroisopropanol, pentafluoropropanol, 1,1,1,3,3,3-hexafluoro-2-methyl-2-propanol, and nonafluoro tertiary butyl alcohol, and a salt of a base with a strong acid, wherein the salt's cation has a pKa in the range of 1 to 4 and the strong acid has a pKa of less than 1, and the aprotic solvent is non-halogenated and selected from the group consisting of a (hetero)aromatic solvent, an alkyl (hetero)aromatic solvent, a (hetero)aromatic ether, and an alkyl (hetero)aryl ether, and wherein: - the base is selected from the group consisting of 4-cyanopyridine, 3-cyanopyridine, 4-chloropyridine, 3-chloropyridine, and a mixture thereof, and - the strong acid is selected from the group consisting of trifluoroacetic acid, hydrochloric acid, methanesulfonic acid, and a mixture thereof. - the base is selected from the group consisting of 4-cyanopyridine, 3-cyanopyridine, 4-chloropyridine, 3-chloropyridine, and a mixture thereof, and - the strong acid is selected from the group consisting of trifluoroacetic acid, hydrochloric acid, methanesulfonic acid, and a mixture thereof.
A liquid receptacle comprising: a wall that defines an interior space ; an accessory component located within the interior space ; and a plurality of self-adjusting connectors that attach the accessory component to the wall , wherein each of the self-adjusting connectors includes a mounting portion attached to the wall at an attachment site, a flange portion attached to the accessory component , and a load-accommodating portion situated between the mounting portion and the flange portion , the load-accommodating portion permitting the mounting portion and the flange portion of each self-adjusting connector to move relative to one another and also permitting limited relative movement between the mounting portions of the self-adjusting connectors , characterized in that mounting portion includes a foot portion attached to the fuel tank wall by a portion of the fuel tank wall that overlaps at least a portion of the foot, wherein the foot portion comprises a body and a flange extending outwardly from the body and adapted to mate with a complimentary groove defined within the fuel tank wall . a wall that defines an interior space ; an accessory component located within the interior space ; and a plurality of self-adjusting connectors that attach the accessory component to the wall , wherein each of the self-adjusting connectors includes a mounting portion attached to the wall at an attachment site, a flange portion attached to the accessory component , and a load-accommodating portion situated between the mounting portion and the flange portion , the load-accommodating portion permitting the mounting portion and the flange portion of each self-adjusting connector to move relative to one another and also permitting limited relative movement between the mounting portions of the self-adjusting connectors , characterized in that mounting portion includes a foot portion attached to the fuel tank wall by a portion of the fuel tank wall that overlaps at least a portion of the foot, wherein the foot portion comprises a body and a flange extending outwardly from the body and adapted to mate with a complimentary groove defined within the fuel tank wall .
Method for operating a hearing device , - wherein a microphone is used to pick up a sound, - wherein the sound is analysed for its concordance with the hearing device wearer's own voice and a feature value (M) is generated that indicates the extent to which the sound is concordant with the hearing device wearer's own voice, - wherein the own voice is a type of sound (G1), - wherein the feature value (M) is compared with a threshold value (S), - wherein the sound is identified as the own voice on the basis of whether the feature value (M) is above or below the threshold value (S), and - wherein the hearing device is changed over between multiple modes of operation on the basis of whether the sound has been identified as the own voice, characterized in that the threshold value (S) is determined on a user basis and is set as an individual threshold value (S) by virtue of the threshold value (S) being determined by means of a calibration method that involves the hearing device wearer's own voice being picked up and multiple individual feature values (M) being generated, and that involves the individual threshold value (S) finally being set on the basis of the generated individual feature values (M), wherein the feature value (M) is generated by means of a filter pair, wherein one of the filters is configured for a maximum attenuation of the own voice and the other filter is configured for a maximum attenuation of another voice. - wherein a microphone is used to pick up a sound, - wherein the sound is analysed for its concordance with the hearing device wearer's own voice and a feature value (M) is generated that indicates the extent to which the sound is concordant with the hearing device wearer's own voice, - wherein the own voice is a type of sound (G1), - wherein the feature value (M) is compared with a threshold value (S), - wherein the sound is identified as the own voice on the basis of whether the feature value (M) is above or below the threshold value (S), and - wherein the hearing device is changed over between multiple modes of operation on the basis of whether the sound has been identified as the own voice,
A computer-implemented method for providing concurrent non-audible communication of relevant information when narrating a document , comprising: opening a document comprising content and at least one meta-information item associated with the content; triggering a narration system to generate and provide audio output of the content; at a current narration point in the document, detecting a meta-information item associated with a piece of content; responsive to the detection of the meta-information item, triggering a haptic actuator to generate and provide haptic feedback associated with the meta-information item concurrently with the audio output of the piece of content with which the meta-information item is associated; responsive to generating and providing the haptic feedback, receiving a first request for additional information associated with the meta-information item; triggering the narration system to generate and provide audio output of a first level of incremental additional information ; receiving a second request for a next incremental level of additional information ; and providing the next incremental level of additional information. opening a document comprising content and at least one meta-information item associated with the content; triggering a narration system to generate and provide audio output of the content; at a current narration point in the document, detecting a meta-information item associated with a piece of content; responsive to the detection of the meta-information item, triggering a haptic actuator to generate and provide haptic feedback associated with the meta-information item concurrently with the audio output of the piece of content with which the meta-information item is associated; responsive to generating and providing the haptic feedback, receiving a first request for additional information associated with the meta-information item; triggering the narration system to generate and provide audio output of a first level of incremental additional information ; receiving a second request for a next incremental level of additional information ; and providing the next incremental level of additional information.
A method for producing xylitol by fermentation of a refined hemicellulose sugar stream derived from a lignocellulosic hydrolysate, comprising converting xylose in the refined hemicellulose sugar stream to xylitol through fermentation by a microorganism, wherein the refined hemicellulose sugar stream comprises: 50 to 90% xylose weight/weight relative to total dissolved sugars, at least 10% hexoses weight/weight relative to total dissolved sugars, wherein glucose and fructose comprise at least 50% weight/weight of the hexoses, less than 200 ppm calcium, and furfural in an amount up to 1000 ppm.
A method for producing a flavored oil, comprising heating a fat to 70 to 130oC in the presence of cheese powder at a content of 3 to 20% by mass with respect to the fat, and removing a solid content after the reaction, wherein a water content in the reaction system before starting raising temperature to the reaction temperature is 1.5% by mass or less, and wherein the reaction is carried out i) under reduced pressure; or ii) in a pressurized state in a reaction system.
An oncolytic virus for use in a method of treating cancer in a subject, the method comprising administering to the subject the oncolytic virus and an increased number of treatment cycles with a chemotherapeutic agent as compared to standard therapy, wherein the increased number of treatment cycles comprises 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25 or more treatment cycles with the chemotherapeutic agent, and wherein the oncolytic virus is a reovirus having IDAC Accession No. 190907-01.
Electric machine for a motor vehicle , comprising a rotor having one or more cooling ducts through which a cooling medium can flow, wherein on an end face of the rotor an annular space is provided which is limited axially inwards and radially outwards and is connected in a communicating manner to the cooling channel or channels , wherein a cover disc is provided which is attached to the end face and delimits the annular space axially outwards and has a central through opening for introducing the cooling medium into the annular space , wherein an inlet is provided which is stationary with respect to the rotary movement of the rotor , by means of which inlet the cooling medium is introduced into the annular space , wherein a stator is provided with at least one winding head which is arranged in such a way that the cooling medium impinges on the winding head after flowing through the rotor during the rotary operation of the rotor , wherein at least one nozzle which discharges the cooling medium is provided at the inlet , by means of which nozzle at least one machine component to be cooled is acted upon by the cooling medium.
A lubricating oil composition for spark-ignition internal combustion engine that is a lubricating oil composition to be used for a spark-ignition internal combustion engine in which a total tension per piston of tensions applied to the piston ring is 100 N or less, the lubricating oil composition being a lubricating oil composition comprising a base oil, (A) a calcium salt of salicylate, at least one selected from (B1) a sodium-based additive and (B2) a magnesium-based additive, (C) an ash-free sulfur-based additive, and (D) a molybdenum-based additive, wherein the content of the component (A) as expressed in terms of a calcium atom is 0.15% by mass or less on a basis of the total amount of the lubricating oil composition; a sum total of the content of the component (B1) as expressed in terms of a sodium atom and the content of the component (B2) as expressed in terms of a magnesium atom is 0.2% by mass or less on a basis of the total amount of the lubricating oil composition; the content of the component (C) as expressed in terms of a sulfur atom is 0.01% by mass or more on a basis of the total amount of the lubricating oil composition; the mass ratio [(Mg and/or Na)/Ca] of the magnesium atom (Mg) contained in the magnesium-based additive and/or the sodium atom (Na) contained in the sodium-based additive to the calcium atom (Ca) is 0.06 to 0.8; and the content of the molybdenum-based additive (D) as expressed in terms of molybdenum atom content is 0.005 to 0.20% by mass on a basis of the total amount of the lubricating oil composition. (A) a calcium salt of salicylate, at least one selected from (B1) a sodium-based additive and (B2) a magnesium-based additive, (C) an ash-free sulfur-based additive, and (D) a molybdenum-based additive, wherein the content of the component (A) as expressed in terms of a calcium atom is 0.15% by mass or less on a basis of the total amount of the lubricating oil composition; a sum total of the content of the component (B1) as expressed in terms of a sodium atom and the content of the component (B2) as expressed in terms of a magnesium atom is 0.2% by mass or less on a basis of the total amount of the lubricating oil composition; the content of the component (C) as expressed in terms of a sulfur atom is 0.01% by mass or more on a basis of the total amount of the lubricating oil composition; the mass ratio [(Mg and/or Na)/Ca] of the magnesium atom (Mg) contained in the magnesium-based additive and/or the sodium atom (Na) contained in the sodium-based additive to the calcium atom (Ca) is 0.06 to 0.8; and the content of the molybdenum-based additive (D) as expressed in terms of molybdenum atom content is 0.005 to 0.20% by mass on a basis of the total amount of the lubricating oil composition.
A method for requesting an uplink transmission resource, the method being applied in a user terminal in a LTE-NR interworking phase in a 5G network, the method comprising: triggering, by the user terminal, an uplink resource Scheduling Request , SR; in response to a preset random access trigger condition being satisfied, triggering , by the user terminal, a contention based random access request; before completing a contention based random access procedure, in response to a preset random access cancellation condition being satisfied, cancelling , by the user terminal, the contention based random access procedure, wherein the preset random access cancellation condition comprises that a UL-grant allocated by a base station is received on PDCCH, and second preset transmission information in the contention based random access procedure is not sent to the base station, characterised in that the second preset transmission information is MSG3. triggering, by the user terminal, an uplink resource Scheduling Request , SR; in response to a preset random access trigger condition being satisfied, triggering , by the user terminal, a contention based random access request; before completing a contention based random access procedure, in response to a preset random access cancellation condition being satisfied, cancelling , by the user terminal, the contention based random access procedure, wherein the preset random access cancellation condition comprises that a UL-grant allocated by a base station is received on PDCCH, and second preset transmission information in the contention based random access procedure is not sent to the base station, characterised in that the second preset transmission information is MSG3.
A method comprising: providing a microchannel having one or more surfaces with fixed endothelial cells on all of the surfaces; and introducing fluid into the microchannel. providing a microchannel having one or more surfaces with fixed endothelial cells on all of the surfaces; and introducing fluid into the microchannel.
Cartridge discharging device comprising a push rod which is guided on a housing having a cartridge receptacle and a handle , can, with each working stroke of a drive lever , be displaced forwards by one step in a forwards direction against a frictional force generated by a frictional contact element by means of a feed element which is displaced when the drive lever moves back and forth, and has a pressure stamp at a front end and a retraction handle at a rear portion, and comprising a compression spring which is seated on the rear portion , characterised in that the length of the compression spring is shorter than the total displacement path of the push rod , such that the compression spring is compressed only in the final phase of the forwards displacement comprising a plurality of working strokes and thereby causes, during a last possible working stroke, a rearwards displacement of the push rod counter to the forwards direction using a restoring force which exceeds the frictional force.
Device for automatic control of buoyancy, heel, trim, depth and altitude in submersible vehicles, comprising: 3 or more non-pressurised tanks of liquid ballast, each with an air inlet valve and an air outlet valve, with electrically controlled opening and closing; an electronic control unit for independent opening and closing of the air inlet and outlet valves of the tanks of liquid ballast; a reservoir for storing compressed air connected to the air inlet valves of the tanks of liquid ballast; wherein said tanks of liquid ballast comprise a free communication with the exterior of the submersible vehicle via one or more holes placed on the inferior part of the tank; and wherein said tanks of liquid ballast are to be in different sections of the submersible vehicle placed along two directions of the horizontal plane of the submersible vehicle; the device being arranged to conjugate the automatic maintenance of neutral buoyancy with the automatic correction of heel and trim angles. 3 or more non-pressurised tanks of liquid ballast, each with an air inlet valve and an air outlet valve, with electrically controlled opening and closing; an electronic control unit for independent opening and closing of the air inlet and outlet valves of the tanks of liquid ballast; a reservoir for storing compressed air connected to the air inlet valves of the tanks of liquid ballast;
A light emitting element comprising, in sequence: an anode ; a first electroluminescent layer over the anode; a first layer over the first electroluminescent layer ; a second layer including a material having an electron-transporting property over and in contact with the first layer ; a region including a material having a hole-transporting property and an electron acceptor material over and in contact with the second layer ; a second electroluminescent layer over the region ; and a cathode over the second electroluminescent layer , wherein the first layer includes at least one selected from the group consisting of an alkali metal, an alkaline earth metal, a rare earth metal, an alkali metal compound, an alkaline earth metal compound, and a rare earth metal compound, wherein the material having the electron-transporting property is a nitrogen-containing condensed aromatic compound or a perylene derivative, wherein the material having the hole-transporting property is an aromatic amine compound or a carbazole derivative, and wherein an emission spectrum of the first electroluminescent layer is different from an emission spectrum of the second electroluminescent layer . an anode ; a first electroluminescent layer over the anode; a first layer over the first electroluminescent layer ; a second layer including a material having an electron-transporting property over and in contact with the first layer ; a region including a material having a hole-transporting property and an electron acceptor material over and in contact with the second layer ; a second electroluminescent layer over the region ; and a cathode over the second electroluminescent layer , wherein the first layer includes at least one selected from the group consisting of an alkali metal, an alkaline earth metal, a rare earth metal, an alkali metal compound, an alkaline earth metal compound, and a rare earth metal compound, wherein the material having the electron-transporting property is a nitrogen-containing condensed aromatic compound or a perylene derivative, wherein the material having the hole-transporting property is an aromatic amine compound or a carbazole derivative, and wherein an emission spectrum of the first electroluminescent layer is different from an emission spectrum of the second electroluminescent layer .