mhurhangee/patent-ind-claim-en huggingface dataset:
An implantable blood pump comprising: a pump housing comprising a wall defining a blood flow conduit extending through the pump housing and an internal volume; a rotor comprising a magnet and disposed within the blood flow conduit ; a magnetic core disposed in the internal volume and extending circumferentially around the blood flow conduit and the rotor , wherein the magnetic core terminates proximate to the wall ; and a controller disposed in the internal volume; a continuous thermal pathway extending through the magnetic core between the controller and the wall for transferring heat to blood transiting the blood flow conduit ; and characterised in that a thermal conductor thermally couples the controller to the magnetic core so as to provide a desired path of least resistance for heat flow generated by the blood pump to blood transitioning the blood flow conduit , wherein the thermal conductor comprises a thermal interface material, and wherein the thermal conductor has a thermal conductivity (k) of at least 5 W/(m ∗ K). a pump housing comprising a wall defining a blood flow conduit extending through the pump housing and an internal volume; a rotor comprising a magnet and disposed within the blood flow conduit ; a magnetic core disposed in the internal volume and extending circumferentially around the blood flow conduit and the rotor , wherein the magnetic core terminates proximate to the wall ; and a controller disposed in the internal volume; a continuous thermal pathway extending through the magnetic core between the controller and the wall for transferring heat to blood transiting the blood flow conduit ; and characterised in that a thermal conductor thermally couples the controller to the magnetic core so as to provide a desired path of least resistance for heat flow generated by the blood pump to blood transitioning the blood flow conduit , wherein the thermal conductor comprises a thermal interface material, and wherein the thermal conductor has a thermal conductivity (k) of at least 5 W/(m ∗ K).
A compound of formula B: or a pharmaceutically acceptable salt or ester thereof, wherein, R 1 is pyridyl, which is substituted with 1-4 substituents selected from alkoxy, R 2 is hydrogen or alkyl; R 3 is hydrogen or methyl; R 4 is hydrogen or methyl; and R 6 is hydrogen. or a pharmaceutically acceptable salt or ester thereof, wherein, R 1 is pyridyl, which is substituted with 1-4 substituents selected from alkoxy, R 2 is hydrogen or alkyl; R 3 is hydrogen or methyl; R 4 is hydrogen or methyl; and R 6 is hydrogen.
Method for supplying an electrical network of an automobile vehicle during a driving phase carried out by means of an electric motor of the automobile vehicle , the automobile vehicle comprising a thermal engine , an alternator driven by the thermal engine , the alternator being connected to the electrical network , and a converter of power ensuring the supply of electrical energy to the electrical network , the supply method comprising a step of comparing a current value (Tc) of a temperature (T) of the converter with a threshold value (T 1 ,T 2 ) and, when the current value (Tc) of the temperature (T) of the converter is greater than the threshold value (T 1 ,T 2 ), a step of reducing the electrical energy supply supplied by the converter to the electrical network , the supply method being characterized in that it comprises, before the step of reduction of the power supply, a step of inspecting a state (E M ) of operation of the thermal motor and, when, during said inspection step , the thermal motor is in operation, the method comprises a step of compensating the step of reducing the electrical energy supply supplied by the converter to the electrical network , by a power supply (A F ) in electrical energy from the electrical network by the alternator .
A ferritic stainless steel for automobile exhaust gas passage components comprising, in mass percent, C: not more than 0.03%, Si: 0.1% to 0.6%, Mn: 0.1% to less than 1.0%, Ni: not more than 0.6%, Cr: 10-20%, Nb: not more than 0.5%, Ti: 0.05-0.3%, Al: more than 0.03% to 0.12%, Cu: more than 1% to 2%, V: 0.01% to 0.2%, N: not more than 0.03%, B: 0.0005-0.02%, O: not more than 0.01%, one or more of Mo, W, Zr and Co in a total of 0.5% to 4%, and the balance of Fe and unavoidable impurities, the composition satisfying Expressions and Nb ≥ 8 C + N 0.02 ≤ Al − 54 / 48 O ≤ 0.1
A circuit for measuring variations of a power supply voltage (VDD) of an electronic circuit , between a first terminal of application of a supply potential VDD and a second terminal defining a reference potential, comprising : a regulator comprising one or several resistors (RR) in series with one or several diodes (DR) between the first and second terminals, the diodes being oriented with their cathode towards the second terminal ; and the mid-point between the resistors and the diodes providing a reference value (Vreg) correspond to a clipped value of the power supply voltage ; and an analog-to-digital converter of a difference between a value (Vmeas) proportional to the power supply voltage and said reference value (Vreg), outputs of the analog-to-digital converter provide at least one first signal constituting a first result (RESULT) representative of variations of the power supply voltage, the first signal being further processed by at least one delay element having an output providing a second result (DRESULT). a regulator comprising one or several resistors (RR) in series with one or several diodes (DR) between the first and second terminals, the diodes being oriented with their cathode towards the second terminal ; and the mid-point between the resistors and the diodes providing a reference value (Vreg) correspond to a clipped value of the power supply voltage ; and an analog-to-digital converter of a difference between a value (Vmeas) proportional to the power supply voltage and said reference value (Vreg), outputs of the analog-to-digital converter provide at least one first signal constituting a first result (RESULT) representative of variations of the power supply voltage, the first signal being further processed by at least one delay element having an output providing a second result (DRESULT).
A sealing apparatus for a gauge changing wheelset, wherein, the sealing apparatus can be arranged between a sliding mechanism of the gauge changing wheelset and an axle-box rear cover of an axle-box body ; the sliding mechanism is axially movable relative to the axle-box body and rotatable relative to the axle-box body , the sealing apparatus comprising a sliding seal and a rotating seal; the sliding seal comprises a sliding ring that can be sleeved outside the sliding mechanism and hermetically connected to the axle-box rear cover ; characterized in that , an inner wall of the sliding ring is axially provided with a through groove which can be slidably fitted with a protrusion axially provided in an outer wall of the sliding mechanism ; the rotating seal comprises a sealing baffle that can be fixed on an outer side of the axle-box rear cover , an outer wall of the sliding ring is circumferentially provided with an annular groove , and a lower end of the sealing baffle extends into the annular groove .
An aerosol-generating device comprising: a cigarette insertion detection sensor configured to detect insertion of a cigarette into an accommodation space of the aerosol-generating device ; a heater configured to heat the cigarette inserted in the accommodation space; at least one temperature sensor configured to measure temperatures of at least two locations inside the aerosol-generating device ; and a controller configured to determine whether the aerosol-generating device is in an overheated state based on the temperatures measured by the at least one temperature sensor when the insertion of the cigarette is detected by the cigarette insertion detection sensor , and control the heater to suspend a heating operation until the overheated state is finished based on the overheated state being detected. a cigarette insertion detection sensor configured to detect insertion of a cigarette into an accommodation space of the aerosol-generating device ; a heater configured to heat the cigarette inserted in the accommodation space; at least one temperature sensor configured to measure temperatures of at least two locations inside the aerosol-generating device ; and a controller configured to determine whether the aerosol-generating device is in an overheated state based on the temperatures measured by the at least one temperature sensor when the insertion of the cigarette is detected by the cigarette insertion detection sensor , and control the heater to suspend a heating operation until the overheated state is finished based on the overheated state being detected.
A yarn comprising a filament A-1 having a single fiber diameter of 10 to 3000 nm and a fiber A-2 having a single fiber diameter greater than the filament A-1, wherein a binder is imparted to the yarn, wherein the binder comprises a sizing agent and/or an oiling agent, wherein the fiber A-2 is a crimped composite fiber in which polytrimethylene terephthalate and polyethylene terephthalate are laminated in a side-by-side manner or an eccentric core-sheath manner, the fiber A-2 having a single-fiber diameter of not less than 5 μm and an apparent crimp rate of 2 to 40%, and wherein the apparent crimp rate is calculated using the following formula; Apparent Crimp Rate % = L 0 − L 1 / L 0 × 100 wherein L0 is the length of the fiber A-2 under a load of 0.222 gr/dtex and L1 is the length of the fiber A-2 after an elapsed time of one minute under a load of 2 mg/dtex.
An imaging device comprising: a display control unit configured to cause a preliminary-notice frame (PE) that gives notice of a specific area to be focused to be displayed on an image obtained by an imaging unit according to a specific part of a subject, wherein: the subject is an animal being a dog or cat, and the specific part is a pupil and the specific area is a pupil area, the imaging device further comprising: an area detection unit configured to detect, in a captured image, at least one front specific area including the specific area to be focused, wherein the at least one front specific area indicates the pupil area of the animal located on a near side of the imaging device , wherein in a case where a plurality of front specific areas has been detected, the display control unit is configured to control display of the preliminary-notice frame (PE) according to the front specific area being closer to a center position of a focus setting frame for setting a focus area. the subject is an animal being a dog or cat, and the specific part is a pupil and the specific area is a pupil area, the imaging device further comprising: an area detection unit configured to detect, in a captured image, at least one front specific area including the specific area to be focused, wherein the at least one front specific area indicates the pupil area of the animal located on a near side of the imaging device , wherein in a case where a plurality of front specific areas has been detected, the display control unit is configured to control display of the preliminary-notice frame (PE) according to the front specific area being closer to a center position of a focus setting frame for setting a focus area. an area detection unit configured to detect, in a captured image, at least one front specific area including the specific area to be focused, wherein the at least one front specific area indicates the pupil area of the animal located on a near side of the imaging device , wherein in a case where a plurality of front specific areas has been detected, the display control unit is configured to control display of the preliminary-notice frame (PE) according to the front specific area being closer to a center position of a focus setting frame for setting a focus area.
A surgical system for selective connection to a robotic arm, the surgical system comprising: an instrument drive unit including a plurality of actuators ; an instrument support platform configured to releasably couple to the instrument drive unit and including a plurality of rotatable members operably associated with the plurality of actuators of the instrument drive unit, each of the plurality of rotatable members being rotatable in response to actuation of at least one of the plurality of actuators; an instrument carriage including a plurality of drive members coupled to the plurality of rotatable members of the instrument support platform, at least one of the plurality of drive members being translatable relative to the instrument carriage in response to rotation of at least one of the plurality of rotatable members; and a surgical instrument configured to releasably couple to the instrument carriage and supporting an end effector that extends distally from the instrument support platform, the end effector being movable in response to translation of the at least one of the plurality of drive members of the instrument carriage, wherein the instrument drive unit includes a gear actuatable by a further actuator of the instrument drive unit, the instrument support platform and the surgical instrument being simultaneously rotatable about a longitudinal axis defined through the instrument support platform in response to actuation of the gear. an instrument drive unit including a plurality of actuators ; an instrument support platform configured to releasably couple to the instrument drive unit and including a plurality of rotatable members operably associated with the plurality of actuators of the instrument drive unit, each of the plurality of rotatable members being rotatable in response to actuation of at least one of the plurality of actuators; an instrument carriage including a plurality of drive members coupled to the plurality of rotatable members of the instrument support platform, at least one of the plurality of drive members being translatable relative to the instrument carriage in response to rotation of at least one of the plurality of rotatable members; and a surgical instrument configured to releasably couple to the instrument carriage and supporting an end effector that extends distally from the instrument support platform, the end effector being movable in response to translation of the at least one of the plurality of drive members of the instrument carriage, wherein the instrument drive unit includes a gear actuatable by a further actuator of the instrument drive unit, the instrument support platform and the surgical instrument being simultaneously rotatable about a longitudinal axis defined through the instrument support platform in response to actuation of the gear.
A pneumatic tire comprising a tread part, wherein the tread part has two or more circumferential grooves extending continuously in a circumferential direction of the tire, a pair of shoulder land parts partitioned by the circumferential grooves and a center land part located between the pair of shoulder land parts, and width direction grooves, and may arbitrarily have sipes; wherein, when a tire cross-sectional width is Wt (mm) and a tire outer diameter is Dt (mm), Wt and Dt satisfy Equation below; wherein, when an area of the entirety of land parts is Sr and a total area of the center land part is Sce, Sr and See satisfy Equation below; wherein the tread part has at least one rubber layer composed of a rubber composition comprising a rubber component; and wherein tan δ at 5°C (5°C tan δ), tan δ at 20°C (20°C tan δ), and tan δ at 50°C (50°C tan δ) of the rubber composition measured as specified in the description under conditions of frequency 10 Hz and elongation strain 2.5% satisfy Equation and Equation below: 1963.4 mm ≦ π / 4 × Dt ∧ 2 / Wt ≦ 2827.4 mm ; 0.35 ≦ Sce / Sr ≦ 0.80 ; 0.01 ≦ 20 ∘ C tan δ + 50 ∘ C tan δ / 2 ≦ 0.17 ; 0.30 ≦ 5 ∘ C tan δ + 20 ∘ C tan δ / 2 ≦ 0.60 , and wherein 5°C tan δ of the rubber composition is 0.65 or more, and 20°C tan δ of the rubber composition is 0.15 or less. wherein the tread part has two or more circumferential grooves extending continuously in a circumferential direction of the tire, a pair of shoulder land parts partitioned by the circumferential grooves and a center land part located between the pair of shoulder land parts, and width direction grooves, and may arbitrarily have sipes; wherein, when a tire cross-sectional width is Wt (mm) and a tire outer diameter is Dt (mm), Wt and Dt satisfy Equation below; wherein, when an area of the entirety of land parts is Sr and a total area of the center land part is Sce, Sr and See satisfy Equation below; wherein the tread part has at least one rubber layer composed of a rubber composition comprising a rubber component; and wherein tan δ at 5°C (5°C tan δ), tan δ at 20°C (20°C tan δ), and tan δ at 50°C (50°C tan δ) of the rubber composition measured as specified in the description under conditions of frequency 10 Hz and elongation strain 2.5% satisfy Equation and Equation below: 1963.4 mm ≦ π / 4 × Dt ∧ 2 / Wt ≦ 2827.4 mm ; 0.35 ≦ Sce / Sr ≦ 0.80 ; 0.01 ≦ 20 ∘ C tan δ + 50 ∘ C tan δ / 2 ≦ 0.17 ; 0.30 ≦ 5 ∘ C tan δ + 20 ∘ C tan δ / 2 ≦ 0.60 , and wherein 5°C tan δ of the rubber composition is 0.65 or more, and 20°C tan δ of the rubber composition is 0.15 or less.
An essentially homogenous population of a chemically synthesized oligonucleotide, which is capable of activating RIG-I and inducing a type I IFN response, wherein said essentially homogenous population means that at least 85 % of the oligonucleotides have the same chemical identity, including the same nucleotide sequence, backbone, modifications, length, and end structures, wherein the oligonucleotide has two blunt ends, wherein the blunt ends are ends of a fully double-stranded section, and wherein the fully double-stranded section is at least 21 and at most 30 base pairs in length, and the double-stranded oligonucleotide has one blunt end bearing a 5' triphosphate attached to the most 5' ribonucleotide and a second blunt end which does not bear a 5' triphosphate, wherein the most 5' ribonucleotide with the triphosphate attached to is G, U or C, wherein the oligonucleotide comprises at least 1, preferably at least 3, more preferably at least 6 ribonucleotide(s) at the 5' end at the blunt end bearing the 5' triphosphate, and wherein the oligonucleotide is free of modifications selected from the group consisting of pseudouridine, 2-thiouridine, 2'Fluorine-dNTP and 2-O-methylated NTP, or wherein the oligonucleotide contains modified nucleotides that do not compromise the type I IFN-inducing activity, wherein the 5' triphosphate is free of any cap structure. which is capable of activating RIG-I and inducing a type I IFN response, wherein said essentially homogenous population means that at least 85 % of the oligonucleotides have the same chemical identity, including the same nucleotide sequence, backbone, modifications, length, and end structures, wherein the oligonucleotide has two blunt ends, wherein the blunt ends are ends of a fully double-stranded section, and wherein the fully double-stranded section is at least 21 and at most 30 base pairs in length, and the double-stranded oligonucleotide has one blunt end bearing a 5' triphosphate attached to the most 5' ribonucleotide and a second blunt end which does not bear a 5' triphosphate, wherein the most 5' ribonucleotide with the triphosphate attached to is G, U or C, wherein the oligonucleotide comprises at least 1, preferably at least 3, more preferably at least 6 ribonucleotide(s) at the 5' end at the blunt end bearing the 5' triphosphate, and wherein the oligonucleotide is free of modifications selected from the group consisting of pseudouridine, 2-thiouridine, 2'Fluorine-dNTP and 2-O-methylated NTP, or wherein the oligonucleotide contains modified nucleotides that do not compromise the type I IFN-inducing activity, wherein the 5' triphosphate is free of any cap structure.
A clutch unit comprises at least two partial clutches , wherein - each partial clutch is configured as a multi-plate clutch with a plate stack , - the two plate stacks are arranged next to each other in the axial direction, - the plate stacks of the partial clutches are arranged in the axial direction without overlapping, and - a hydraulic actuating member is associated with each plate stack in order to axially compress the plate stack and thus enable a torque flow through the associated partial clutch , and wherein the actuating members each comprise a piston-cylinder unit and the piston-cylinder units are arranged concentrically with respect to one another, characterised in that - the actuating members are axially supported in relation to a carrier device of the clutch unit , which carrier device is provided for rotationally fixed connection with a transmission , wherein the carrier device radially extends beyond the plate stacks of the partial clutches , and the carrier device is configured to be attached to a transmission in a region radially outside the plate stacks . - each partial clutch is configured as a multi-plate clutch with a plate stack , - the two plate stacks are arranged next to each other in the axial direction, - the plate stacks of the partial clutches are arranged in the axial direction without overlapping, and - a hydraulic actuating member is associated with each plate stack in order to axially compress the plate stack and thus enable a torque flow through the associated partial clutch , and wherein the actuating members each comprise a piston-cylinder unit and the piston-cylinder units are arranged concentrically with respect to one another, - the actuating members are axially supported in relation to a carrier device of the clutch unit , which carrier device is provided for rotationally fixed connection with a transmission , wherein the carrier device radially extends beyond the plate stacks of the partial clutches , and the carrier device is configured to be attached to a transmission in a region radially outside the plate stacks .
A non-naturally occurring or engineered composition for expression in a cell, comprising: a single polynucleotide comprising sequences for expression of two or more CRISPR-Cas9 system guides from a single promoter, wherein each system guide is a chimeric RNA (chiRNA) and comprises from 5' to 3' a guide sequence that hybridizes to a DNA target at a locus of interest, a tracr mate sequence, and a tracr sequence, and wherein the tracr sequence of a first chiRNA is linked to the guide sequence of a second chiRNA by a linker sequence.