Tubular connection device comprising: • a female connector , into which a male end piece provided with an annular groove is intended to be inserted, the female connector being provided with two lateral slits which are symmetrical with respect to a radial axis (A); • a U-shaped locking clip , which comprises a head and two branches and straddles the female connector , each branch extending into a lateral slit and ending with a foot ; • two lateral guide systems , which are symmetrical with respect to the radial axis (A) and cooperate with the feet of the clip in order to keep it in a raised position of disconnection from the male end piece or in a pressed-in position for locking the male end piece in the female connector , each guide system comprising: o a notch , which is formed in the female connector adjacent to the lateral slit ; o a plate , which delimits a lower edge of the notch and on which the foot rests in order to keep the clip in an intermediate position between the raised position and the pressed-in position in the absence of a male end piece ; • a ring , which is arranged against an inner wall of the female connector ; the device being characterized in that each guide system further comprises a lug , which is arranged on a flexible tab carried by the ring and is intended to at least partly fill the notch and the plate when the male end piece is inserted into the connector , its annular groove being intended to be opposite the lateral slits to allow the clip to pass into a pressed-in position or into a raised position. • a female connector , into which a male end piece provided with an annular groove is intended to be inserted, the female connector being provided with two lateral slits which are symmetrical with respect to a radial axis (A); • a U-shaped locking clip , which comprises a head and two branches and straddles the female connector , each branch extending into a lateral slit and ending with a foot ; • two lateral guide systems , which are symmetrical with respect to the radial axis (A) and cooperate with the feet of the clip in order to keep it in a raised position of disconnection from the male end piece or in a pressed-in position for locking the male end piece in the female connector , each guide system comprising: o a notch , which is formed in the female connector adjacent to the lateral slit ; o a plate , which delimits a lower edge of the notch and on which the foot rests in order to keep the clip in an intermediate position between the raised position and the pressed-in position in the absence of a male end piece ; o a notch , which is formed in the female connector adjacent to the lateral slit ; o a plate , which delimits a lower edge of the notch and on which the foot rests in order to keep the clip in an intermediate position between the raised position and the pressed-in position in the absence of a male end piece ; • a ring , which is arranged against an inner wall of the female connector ; the device being characterized in that each guide system further comprises a lug , which is arranged on a flexible tab carried by the ring and is intended to at least partly fill the notch and the plate when the male end piece is inserted into the connector , its annular groove being intended to be opposite the lateral slits to allow the clip to pass into a pressed-in position or into a raised position. <EOS>