mhurhangee/patent-ind-claim-en huggingface dataset:
A method for detecting a single base substitution at a single nucleotide polymorphism site contained in a nucleic acid sample by utilizing a polymerase chain reaction, the method combines the steps of: (a) hybridizing to the nucleic acid a mutant primer in which the base of the third nucleotide from the 3' end corresponds to the base of a mutant nucleotide of the single nucleotide polymorphism, in which the base of the second nucleotide from the 3' end is not complementary to the base of the corresponding nucleotide of the nucleic acid, and in which the bases of the other nucleotides are complementary to bases of the corresponding nucleotides of the nucleic acid; (b) elongating the mutant primer with a DNA polymerase and deoxyribonucleoside triphosphate that is a substrate thereof; and (c) determining whether the mutant primer is elongated or not based on the presence or absence of an amplification product of the polymerase chain reaction, and thereby, detecting the single base substitution contained in the nucleic acid sample based on whether the mutant primer is elongated or not. (a) hybridizing to the nucleic acid a mutant primer in which the base of the third nucleotide from the 3' end corresponds to the base of a mutant nucleotide of the single nucleotide polymorphism, in which the base of the second nucleotide from the 3' end is not complementary to the base of the corresponding nucleotide of the nucleic acid, and in which the bases of the other nucleotides are complementary to bases of the corresponding nucleotides of the nucleic acid; (b) elongating the mutant primer with a DNA polymerase and deoxyribonucleoside triphosphate that is a substrate thereof; and (c) determining whether the mutant primer is elongated or not based on the presence or absence of an amplification product of the polymerase chain reaction, and thereby, detecting the single base substitution contained in the nucleic acid sample based on whether the mutant primer is elongated or not.
A slide shower, which comprises a fixed portion and a lifting and lowering rod slidably connected to the fixed portion , a water outflowing terminal is disposed on the lifting and lowering rod ; characterized in that : a gravity balancer is disposed between the fixed portion and the lifting and lowering rod , the gravity balancer comprises an elastic body and a first pull rope , the elastic body is assembled to the fixed portion , the first pull rope is configured to be pulled and is connected to the lifting and lowering rod , and a function generated by a pulling force applied to the first pull rope and a function of an elastic force generated by the elastic body are opposite, wherein the gravity balancer further comprises a fixed pulley rotatably assembled to the fixed portion and a second pull rope ; one end of the elastic body is fixedly connected to the fixed portion , the second pull rope is connected to another end of the elastic body , and the second pull rope is connected to the fixed pulley to drive the fixed pulley to rotate in a forward direction; the first pull rope is configured to be pulled and is connected to the lifting and lowering rod , and another end of the first pull rope is connected to the fixed pulley to drive the fixed pulley to rotate in a reverse direction, and wherein a movable pulley is assembled to the another end of the elastic body , one end of the second pull rope is fixedly connected to the fixed portion , and another end of the second pull rope wraps around the movable pulley and is fixed to the fixed pulley ; a connection position between the first pull rope and the lifting and lowering rod is lower than a position of the fixed pulley .
Fitting component for fastening a structural element in an opening bound by a support surface , comprising at least the following elements: - a spacer element which can be attached to the support surface ; - a guide part having a sleeve-shaped shank which can be inserted into an aperture of the structural element ; - wherein the shank has an opening which serves to guide a fastening element that makes it possible to establish a force-fitting connection between the spacer element and the structural element , wherein - the fitting component is embodied in at least two pieces as the spacer element and the guide part , - the guide part has a foot part in addition to the shank , - and the guide part can be attached by the foot part to the spacer element during pre-fitting; characterized in that the foot part of the guide part has one or more retaining elements such as protrusions, clips, bolts, brackets or tabs, and the spacer element has regions which are designed as connection regions and can thus cooperate with the retaining elements on the foot part of the guide part in such a way that a connection between the guide part and the spacer element can be achieved, wherein the retaining elements are two or more locking hooks which, during pre-fitting, engage in holes or bores of the spacer element and latch therein. - a spacer element which can be attached to the support surface ; - a guide part having a sleeve-shaped shank which can be inserted into an aperture of the structural element ; - wherein the shank has an opening which serves to guide a fastening element that makes it possible to establish a force-fitting connection between the spacer element and the structural element , wherein - the fitting component is embodied in at least two pieces as the spacer element and the guide part , - the guide part has a foot part in addition to the shank , - and the guide part can be attached by the foot part to the spacer element during pre-fitting;
An inhibitor of a mammalian complement system for use in treating a disease or injury of the PNS or CNS by facilitating axonal regeneration in a subject, wherein the inhibitor is an anti-sense oligonucleotide, aptamer, miRNA, ribozyme or siRNA that blocks expression of one or more of C3 convertase, C5, C6, C7, C8, C9.
A method for providing a notification based on breaching a plurality of geo-fence perimeters, comprising: detecting a breach of a first geo-fence perimeter of the plurality of geo-fence perimeters; recording the breach of the first geo-fence perimeter by incrementing or decrementing a counter; detecting a breach of a second geo-fence perimeter of the plurality of geo-fence perimeters; recording the breach of the second geo-fence perimeter by incrementing or decrementing the counter; determining whether the counter reaches a threshold; and based on the counter reaching the threshold, issuing an alert. detecting a breach of a first geo-fence perimeter of the plurality of geo-fence perimeters; recording the breach of the first geo-fence perimeter by incrementing or decrementing a counter; detecting a breach of a second geo-fence perimeter of the plurality of geo-fence perimeters; recording the breach of the second geo-fence perimeter by incrementing or decrementing the counter; determining whether the counter reaches a threshold; and based on the counter reaching the threshold, issuing an alert.
A low density frosting comprising: from 50 to 85 weight percent sweetening agent based on total weight frosting; from 15 to 30 weight percent total fat ingredients based on total weight frosting, the total fat ingredients comprising: a major amount of non-hydrogenated palm oil-based shortening ingredient, and 5 to 25 weight percent crystal-enhancing fat ingredient, based on weight total fat ingredients, wherein the crystal-enhancing fat ingredient is a fully hydrogenated room temperature solid fat; wherein the total fat ingredients comprise at least 90 weight percent of a blend of the non-hydrogenated palm oil-based shortening ingredient and the fully hydrogenated crystal-enhancing fat ingredient, based on the weight of the total fat ingredients; and from 10 to 20 weight percent water based on total weight frosting; wherein the frosting has a density in a range from 0.75 to 0.95 grams per cubic centimeter; and the frosting contains less than 2 weight percent trans fat. from 50 to 85 weight percent sweetening agent based on total weight frosting; from 15 to 30 weight percent total fat ingredients based on total weight frosting, the total fat ingredients comprising: a major amount of non-hydrogenated palm oil-based shortening ingredient, and 5 to 25 weight percent crystal-enhancing fat ingredient, based on weight total fat ingredients, wherein the crystal-enhancing fat ingredient is a fully hydrogenated room temperature solid fat; wherein the total fat ingredients comprise at least 90 weight percent of a blend of the non-hydrogenated palm oil-based shortening ingredient and the fully hydrogenated crystal-enhancing fat ingredient, based on the weight of the total fat ingredients; and a major amount of non-hydrogenated palm oil-based shortening ingredient, and 5 to 25 weight percent crystal-enhancing fat ingredient, based on weight total fat ingredients, wherein the crystal-enhancing fat ingredient is a fully hydrogenated room temperature solid fat; wherein the total fat ingredients comprise at least 90 weight percent of a blend of the non-hydrogenated palm oil-based shortening ingredient and the fully hydrogenated crystal-enhancing fat ingredient, based on the weight of the total fat ingredients; and from 10 to 20 weight percent water based on total weight frosting;
A tubular smoke shaft section comprising plurality of vertical walls in connection with each other and arranged to border a hollow upwards and downwards open smoke guiding channel , wherein each said wall has a sandwich structure and comprises a first face sheet forming an inner face of the wall and a second face sheet forming an outer face of the wall , and an insulation layer between said first face sheet and said second face sheet , the tubular smoke shaft section having an upper end (E1) and a lower end (E2), in particular shaped to form counterparts for each other for enabling piling of tubular smoke shaft sections on top of each other, wherein the tubular smoke shaft section comprises fixing members comprising one or more first horizontal plate portions extending horizontally at the upper end (E1) of the smoke shaft section , and one or more second horizontal plate portions extending horizontally at the lower end (E2) of the smoke shaft section , wherein said first and second horizontal plate portions (11a,12a;13a,13b) are positioned such that they overlap vertically, characterized in that said first and second horizontal plate portions extend inside the smoke guiding channel or inside the vertical projection of the smoke guiding channel .
A coil spring having a spring wire formed into a helical shape axially extending from one side to the other side so as to include a first end coil part having a first bearing surface that is arranged on one side in the axial direction of the coil spring and faces one side in the axial direction of the coil spring , a second end coil part having a second bearing surface that is arranged on the other side in the axial direction of the coil spring and faces the other side in the axial direction of the coil spring and a central coil part between the first and second end coil parts , wherein the first end coil part includes a first end coil part edge region that extends from a first end on one side in the axial direction of the coil spring to a part forming a first reference point on one side in the axial direction where a space between coils that are adjacent to each other in an axial direction is zero in the natural length state, and a first end coil part transitional region that extends from the first end coil edge region to the central coil part , the first end coil part edge region is bent toward one side in the axial direction of the coil spring as compared with the first end coil part transitional region ; the coil spring being characterized in that , the first bearing surface extends from the first end coil part edge region to the first end coil part transitional region across a border between the first end coil part edge region and the first end coil part transitional region . the first end coil part edge region is bent toward one side in the axial direction of the coil spring as compared with the first end coil part transitional region ; the coil spring being characterized in that , the first bearing surface extends from the first end coil part edge region to the first end coil part transitional region across a border between the first end coil part edge region and the first end coil part transitional region .
A body tissue location measurement system comprising: a plurality of ultrasonic elements placed in different parts on the surface of a body; an external sensor configured for measuring a position of the ultrasonic elements; an ultrasonic propagation model holding unit configured for holding an ultrasonic propagation model; an ultrasonic propagation time calculation unit configured for calculating an ultrasonic propagation time based on the ultrasonic model and the ultrasonic element position; an ultrasonic image configuration unit configured for configuring an ultrasonic image from the ultrasonic propagation time as well as an ultrasonic signal received by each element; and a body tissue location calculation unit configured for calculating a location of a target body tissue from the ultrasonic image, an ultrasonic transmitting/receiving unit configured for amplifying and processing electrical signals received from the ultrasonic elements , and for transmitting the electrical signals to the ultrasonic image configuration unit , wherein the ultrasonic elements are provided independently, so that their relative position varies in accordance with movement. a plurality of ultrasonic elements placed in different parts on the surface of a body; an external sensor configured for measuring a position of the ultrasonic elements; an ultrasonic propagation model holding unit configured for holding an ultrasonic propagation model; an ultrasonic propagation time calculation unit configured for calculating an ultrasonic propagation time based on the ultrasonic model and the ultrasonic element position; an ultrasonic image configuration unit configured for configuring an ultrasonic image from the ultrasonic propagation time as well as an ultrasonic signal received by each element; and a body tissue location calculation unit configured for calculating a location of a target body tissue from the ultrasonic image, an ultrasonic transmitting/receiving unit configured for amplifying and processing electrical signals received from the ultrasonic elements , and for transmitting the electrical signals to the ultrasonic image configuration unit , wherein the ultrasonic elements are provided independently, so that their relative position varies in accordance with movement.
A power amplifier for a transmitter circuit , the power amplifier comprising: at least one field-effect transistor having a gate terminal and a bulk terminal , wherein the at least one field-effect transistor is configured to receive an input voltage at the gate terminal and a dynamic bias voltage at the bulk terminal ; and a bias-voltage generation circuit ; wherein: the input voltage is a linear function of an input signal; and the bias-voltage generation circuit is configured to generate the dynamic bias voltage as a nonlinear function of an envelope of the input signal; wherein the bias-voltage generation circuit comprises: a digital signal-processing circuit configured to apply the nonlinear function in a digital domain to generate a digital bias signal; a digital-to-analog converter configured to convert the digital bias signal to an analog domain to generate the dynamic bias voltage; characterized in that the digital signal-processing circuit is configured to: measure a signal output from the power amplifier to determine a metric of nonlinearity of the power amplifier ; and adjust coefficients of the nonlinear function when the determined metric of nonlinearity exceeds a threshold. at least one field-effect transistor having a gate terminal and a bulk terminal , wherein the at least one field-effect transistor is configured to receive an input voltage at the gate terminal and a dynamic bias voltage at the bulk terminal ; and a bias-voltage generation circuit ; wherein: the input voltage is a linear function of an input signal; and the bias-voltage generation circuit is configured to generate the dynamic bias voltage as a nonlinear function of an envelope of the input signal; the input voltage is a linear function of an input signal; and the bias-voltage generation circuit is configured to generate the dynamic bias voltage as a nonlinear function of an envelope of the input signal; a digital signal-processing circuit configured to apply the nonlinear function in a digital domain to generate a digital bias signal; a digital-to-analog converter configured to convert the digital bias signal to an analog domain to generate the dynamic bias voltage; characterized in that the digital signal-processing circuit is configured to: measure a signal output from the power amplifier to determine a metric of nonlinearity of the power amplifier ; and adjust coefficients of the nonlinear function when the determined metric of nonlinearity exceeds a threshold. measure a signal output from the power amplifier to determine a metric of nonlinearity of the power amplifier ; and adjust coefficients of the nonlinear function when the determined metric of nonlinearity exceeds a threshold.
A composition comprising a perfluorocarbon droplet emulsion for use in a method of treating a patient for a condition characterized by an excess blood concentration of dissolved gas in at least one targeted region of the patient, the method comprising: administering the composition into the blood of the patient; insonifying the at least one target region sufficient to achieve formation of microbubbles by droplet vaporization of at least a portion of the perfluorocarbon droplets present in the blood; whereby a concentration gradient favoring movement of gas molecules from the blood into the microbubbles is established for a time frame, wherein the established concentration gradient is calculated to achieve sufficient but not excess removal of dissolved gas from the target region, and wherein the established concentration gradient is calculated according to a model comprising as variables solubility of the gas in both the blood and the microbubbles, wherein the dissolved gas is selected from nitrogen, carbon monoxide, and carbon dioxide. administering the composition into the blood of the patient; insonifying the at least one target region sufficient to achieve formation of microbubbles by droplet vaporization of at least a portion of the perfluorocarbon droplets present in the blood; whereby a concentration gradient favoring movement of gas molecules from the blood into the microbubbles is established for a time frame, wherein the established concentration gradient is calculated to achieve sufficient but not excess removal of dissolved gas from the target region, and wherein the established concentration gradient is calculated according to a model comprising as variables solubility of the gas in both the blood and the microbubbles, wherein the dissolved gas is selected from nitrogen, carbon monoxide, and carbon dioxide.
Device for applying a product to be distributed on the skin of a user by iontophoresis comprising: - at least one means of storage for storing the product to be distributed; - at least one distribution cavity able to receive the product to be distributed; - at least one first electrode for iontophoresis; - an electronic control circuit ; - means for measuring a physical or physicochemical parameter connected to the electronic control circuit and configured to send a signal (E 1 , E 11 , E 12 ) indicating the parameter measurement, characterised in that the first electrode for iontophoresis and the means for measuring are installed in the distribution cavity , the electronic control circuit being configured to compare the measured value of the physical or physicochemical parameter in the cavity with a threshold reference value (E 2 , E 21 , E 22 ) so as to detect an absence of product in the cavity . - at least one means of storage for storing the product to be distributed; - at least one distribution cavity able to receive the product to be distributed; - at least one first electrode for iontophoresis; - an electronic control circuit ; - means for measuring a physical or physicochemical parameter connected to the electronic control circuit and configured to send a signal (E 1 , E 11 , E 12 ) indicating the parameter measurement,
A production plant for laying fiber tapes , the production plant comprising: - a laying device having an unwinder receptacle and at least two unwinders arranged next to one another on the unwinder receptacle , which unwinders each comprise a receiving device for receiving a raw material reel and a cutting unit for cutting the fiber tape ; - a depositing device having a depositing surface for receiving the fiber tape unwound from the raw material reel , the depositing surface of the depositing device and the unwinder of the laying device being displaceable relative to one another in the laying direction , whereby the fiber tape can be unwound in stripes onto the depositing surface , characterized in that the at least two unwinders are coupled to an unwinder receptacle of the laying device by means of a linear guide and are movable independently of each other in the laying direction relative to the unwinder receptacle . - a laying device having an unwinder receptacle and at least two unwinders arranged next to one another on the unwinder receptacle , which unwinders each comprise a receiving device for receiving a raw material reel and a cutting unit for cutting the fiber tape ; - a depositing device having a depositing surface for receiving the fiber tape unwound from the raw material reel , the depositing surface of the depositing device and the unwinder of the laying device being displaceable relative to one another in the laying direction , whereby the fiber tape can be unwound in stripes onto the depositing surface ,