mhurhangee/patent-ind-claim-en huggingface dataset:
A method for analyzing MSI status of a colorectal, endometrial, or gastric cancer by analyzing MSI loci in a biological sample, the method comprising the step of: - determining the number of nucleotides in the following homopolymeric repeats as mapped to GRCh38/hg38 human reference genome: homopolymeric repeat comprising 11 consecutive adenines localized to human DIDO1 gene and starting at position chr20:62,905,340; homopolymeric repeat comprising 11 consecutive adenines localized to human MRE11 gene and starting at position chr11:94,479,765; homopolymeric repeat comprising 10 consecutive adenines localized to human SULF2 gene and starting at position chr20:47,657,577; and homopolymeric repeat comprising 8 consecutive adenines localized to human ACVR2A gene and starting at position chr2:147,926,117. - determining the number of nucleotides in the following homopolymeric repeats as mapped to GRCh38/hg38 human reference genome: homopolymeric repeat comprising 11 consecutive adenines localized to human DIDO1 gene and starting at position chr20:62,905,340; homopolymeric repeat comprising 11 consecutive adenines localized to human MRE11 gene and starting at position chr11:94,479,765; homopolymeric repeat comprising 10 consecutive adenines localized to human SULF2 gene and starting at position chr20:47,657,577; and homopolymeric repeat comprising 8 consecutive adenines localized to human ACVR2A gene and starting at position chr2:147,926,117. homopolymeric repeat comprising 11 consecutive adenines localized to human DIDO1 gene and starting at position chr20:62,905,340; homopolymeric repeat comprising 11 consecutive adenines localized to human MRE11 gene and starting at position chr11:94,479,765; homopolymeric repeat comprising 10 consecutive adenines localized to human SULF2 gene and starting at position chr20:47,657,577; and homopolymeric repeat comprising 8 consecutive adenines localized to human ACVR2A gene and starting at position chr2:147,926,117.
Beam measurement circuitry for use in a user equipment, UE (110, 130; 450), of a wireless telecommunications network having at least one NodeB (110, 120; 310, 370), the beam measurement reporting circuitry configured to: receive at the UE (110, 130; 450), from the network, beam measurement configuration data requesting a selection of a non-zero integer number, N, beams by the UE (110, 130; 450); and measure, in response to a measurement request from the network, signal qualities for a plurality of received beams originating from a beam source of the network, to select N beams to evaluate a serving cell and one or more neighbouring cells of the UE (110, 130; 450), wherein the selection of the N beams depends upon the signal quality measurements; report to the neighbouring cells of the UE (110, 130; 450), the beam measurement results specifying the N selected beams; wherein selection of the at least one beam from the plurality of received beams of the respective beam source is performed based on a selected beam having a signal quality greater than a measured signal quality of an active beam. receive at the UE (110, 130; 450), from the network, beam measurement configuration data requesting a selection of a non-zero integer number, N, beams by the UE (110, 130; 450); and measure, in response to a measurement request from the network, signal qualities for a plurality of received beams originating from a beam source of the network, to select N beams to evaluate a serving cell and one or more neighbouring cells of the UE (110, 130; 450), wherein the selection of the N beams depends upon the signal quality measurements; report to the neighbouring cells of the UE (110, 130; 450), the beam measurement results specifying the N selected beams; wherein selection of the at least one beam from the plurality of received beams of the respective beam source is performed based on a selected beam having a signal quality greater than a measured signal quality of an active beam.
A head-mounted display apparatus comprising: a display ; an optic block defining a beam splitter and a transparent convex surface , in optical communication with the display , to transmit light emitted by the display ; a concave reflective surface , in optical communication with the beam splitter and the transparent convex surface , to receive the light emitted by the display and transmitted by the beam splitter and to reflect an image of the display to a wearer of the head-mounted display apparatus via the beam splitter , wherein the transparent convex surface has a radius of curvature different from a radius of curvature of the concave reflective surface ; and a tunable lens comprising electro-active material, the tunable lens being disposed between the transparent convex surface and the concave reflective surface and having a variable optical power, to vary a focus of the image of the display reflected to the wearer. a display ; an optic block defining a beam splitter and a transparent convex surface , in optical communication with the display , to transmit light emitted by the display ; a concave reflective surface , in optical communication with the beam splitter and the transparent convex surface , to receive the light emitted by the display and transmitted by the beam splitter and to reflect an image of the display to a wearer of the head-mounted display apparatus via the beam splitter , wherein the transparent convex surface has a radius of curvature different from a radius of curvature of the concave reflective surface ; and a tunable lens comprising electro-active material, the tunable lens being disposed between the transparent convex surface and the concave reflective surface and having a variable optical power, to vary a focus of the image of the display reflected to the wearer.
A shade for a portable device having an electronic display, said shade comprising: a plurality of blades configured to splay open to form a planar surface for blocking sunlight; and a mount for securing the planar surface to the portable device substantially adjacent to, and aligned substantially parallel with, the electronic display to position the blades to increase the footprint of the portable device , for shading the eyes of a user from a light source when the device is placed between the user and the light source and wherein the mount comprises a grip to allow the user to grip the shade and the device in a single hand. a plurality of blades configured to splay open to form a planar surface for blocking sunlight; and a mount for securing the planar surface to the portable device substantially adjacent to, and aligned substantially parallel with, the electronic display to position the blades to increase the footprint of the portable device , for shading the eyes of a user from a light source when the device is placed between the user and the light source and wherein the mount comprises a grip to allow the user to grip the shade and the device in a single hand.
Lidar unit , in particular laser scanner, for laser-based distance measurement for a vehicle, with a transmitter module designed to emit a laser beam, and a receiver module designed to receive a reflection of the emitted laser beam, wherein the lidar unit has a mounting element for attaching the transmitter module and the receiver module , the mounting element and the transmitter module have corresponding first stop surfaces for alignment of the transmitter module on the mounting element , the mounting element and the receiver module have corresponding second stop surfaces for alignment of the receiver module on the mounting element , the transmitter module is pre-calibrated with respect to its first stop surface , and the receiver module is pre-calibrated with respect to its second stop surface , characterized in that the first stop surfaces and/or the second stop surfaces each have a plurality of corresponding surface areas, which are arranged at an angle to one another or in a plurality of parallel planes. a receiver module designed to receive a reflection of the emitted laser beam, wherein the lidar unit has a mounting element for attaching the transmitter module and the receiver module , the mounting element and the transmitter module have corresponding first stop surfaces for alignment of the transmitter module on the mounting element , the mounting element and the receiver module have corresponding second stop surfaces for alignment of the receiver module on the mounting element , the transmitter module is pre-calibrated with respect to its first stop surface , and the receiver module is pre-calibrated with respect to its second stop surface , characterized in that the first stop surfaces and/or the second stop surfaces each have a plurality of corresponding surface areas, which are arranged at an angle to one another or in a plurality of parallel planes.
A fastening member comprising: a base panel having a base panel lateral centerline and comprising a base panel upper edge , a base panel lower edge , a base panel upper endpoint and a base panel lower endpoint , a closure member extending laterally from the base panel, the closure member comprising a closure member upper edge , a closure member lower edge , a closure member upper endpoint , a closure member lower endpoint , and a proximal portion , and a fastening element disposed on the closure member, the fastening element comprising a fastening element lateral centerline , a fastening element upper edge and a fastening element lower edge , wherein the closure member upper edge comprises a concave portion, the concave portion being formed along the fastening element upper edge , wherein the closure member lower edge comprises a convex portion, the convex portion being formed along the fastening element lower edge , and wherein the closure member extends upwardly laterally; characterized in that the closure member is joined to the base panel , and in that the base panel includes an elastomeric material, such that at least a portion of the base panel is extensible. a base panel having a base panel lateral centerline and comprising a base panel upper edge , a base panel lower edge , a base panel upper endpoint and a base panel lower endpoint , a closure member extending laterally from the base panel, the closure member comprising a closure member upper edge , a closure member lower edge , a closure member upper endpoint , a closure member lower endpoint , and a proximal portion , and a fastening element disposed on the closure member, the fastening element comprising a fastening element lateral centerline , a fastening element upper edge and a fastening element lower edge , wherein the closure member upper edge comprises a concave portion, the concave portion being formed along the fastening element upper edge , wherein the closure member lower edge comprises a convex portion, the convex portion being formed along the fastening element lower edge , and wherein the closure member extends upwardly laterally; characterized in that the closure member is joined to the base panel , and in that the base panel includes an elastomeric material, such that at least a portion of the base panel is extensible.
A heat exchange element for cooling or heating rooms, comprising a thermally conductive pipe for a heat exchange fluid to flow through, and at least one thermally conductive plate element that is essentially planar on both sides and parallel on the sides for absorbing ambient heat and thermally conducting the ambient heat to the pipe and/or taking up thermal heat from the pipe and dissipating the thermal heat to the environment, with the pipe being arranged on at least one plate element or between at least two plate elements of a plate element arrangement, and a contact means being provided for thermal contact, wherein the contact means comprises a connecting means, and the plate element , in the area of a plate-element contact surface for thermally conductive contact with a pipe contact surface , is adapted on the pipe contact surface by means of a fit with a reduced material thickness d compared to a thickness D of the plate element , to enlarge the contact surfaces , and the connecting means comprises a soldered connection or an adhesive connection characterized in that the plate element has a plate thickness D of 0.5 to 3 mm and the fit in the edge area or in the entire cross section is in the form of a segment of a circle, with a depth of 2 to 12% of the outer diameter of the tube, the tube being operatively connected in a meandering manner to the at least one plate element , and the tube and the plate element are straight in the region of the fit, with the curved tube sections protruding laterally beyond the plate element. and the plate element , in the area of a plate-element contact surface for thermally conductive contact with a pipe contact surface , is adapted on the pipe contact surface by means of a fit with a reduced material thickness d compared to a thickness D of the plate element , to enlarge the contact surfaces , and the connecting means comprises a soldered connection or an adhesive connection characterized in that the plate element has a plate thickness D of 0.5 to 3 mm and the fit in the edge area or in the entire cross section is in the form of a segment of a circle, with a depth of 2 to 12% of the outer diameter of the tube, the tube being operatively connected in a meandering manner to the at least one plate element , and the tube and the plate element are straight in the region of the fit, with the curved tube sections protruding laterally beyond the plate element.
Method of operating a heat exchanger presenting: • a first gas inlet , a first gas outlet and a first gas flow path extending from the first gas inlet to the first gas outlet ; • a second gas inlet , a second gas outlet and a second gas flow path extending from the second gas inlet to the second gas outlet ; the first flow path being in thermal contact with but physically separated from the second flow path by means of a gas-impermeable heat-conducting barrier ; • the first flow path containing a first heat-regenerative packing in physical and heat-conducting contact with the barrier ; and • the second flow path containing a second heat-conductive packing in physical and heat-conducting contact with the barrier , method whereby the heat exchanger alternates between: • a first operating stage during which a hot gas flows from the first gas inlet to the first gas outlet along the first gas flow path , thereby coming into contact with and heating the first heat-regenerative packing , while no gas flows along the second gas flow path , and • a second operating stage during which a gas to be heated flows from the second gas inlet to the second gas outlet along the second gas flow path , thereby coming into contact with and being heated by the second heat-conductive packing while no gas flows along the first gas flow path . • a first gas inlet , a first gas outlet and a first gas flow path extending from the first gas inlet to the first gas outlet ; • a second gas inlet , a second gas outlet and a second gas flow path extending from the second gas inlet to the second gas outlet ; the first flow path being in thermal contact with but physically separated from the second flow path by means of a gas-impermeable heat-conducting barrier ; • the first flow path containing a first heat-regenerative packing in physical and heat-conducting contact with the barrier ; and • the second flow path containing a second heat-conductive packing in physical and heat-conducting contact with the barrier , method whereby the heat exchanger alternates between: • a first operating stage during which a hot gas flows from the first gas inlet to the first gas outlet along the first gas flow path , thereby coming into contact with and heating the first heat-regenerative packing , while no gas flows along the second gas flow path , and • a second operating stage during which a gas to be heated flows from the second gas inlet to the second gas outlet along the second gas flow path , thereby coming into contact with and being heated by the second heat-conductive packing while no gas flows along the first gas flow path .
Tweezers for removing ticks from the skin including an outer sleeve , in which pincers are slidably mounted, which include two pincer halves which are elastically spread apart from one another and which are integrally constructed with a rod-shaped gripping section , the end section of which projects out of the sleeve , wherein the pincer halves have end sections extending towards one another for gripping a tick and the end sections project forwardly out of the sleeve , in an initial position of the pincers , with a spacing from one another, wherein the end sections are forced together on pressing of the sleeve against the skin through the front edge of the sleeve in order to be able to grip the tick, characterised in that when the pincers are retracted into the sleeve they are locked by a locking device, which may be released only by pressing a resilient tongue cut free from the wall of the sleeve inwardly, that the locking device includes a resilient web cut free from the gripping section of the pincers , which has a locking lug at its free end, which, in the relaxed state of the web , projects outwardly beyond the outer contour of the gripping section and, radially inwards, has a free space at least as broad as the locking lug and that the sleeve has a recess before its cut free tongue in the axial direction, into which the locking lug can engage.
A multiphasic osteochondral scaffold for osteochondral defect repair, the scaffold comprising a bone phase and a cartilage phase, wherein the bone phase comprises a support matrix and the cartilage phase comprises a polymeric matrix, and the scaffold comprises a non-porous layer between the bone phase and the cartilage phase, wherein the polymeric matrix partially overlaps with and is embedded in the support matrix, and the non-porous layer is present in the region of overlap and acts to join the support matrix to the polymeric matrix, wherein, in use, the non-porous layer prevents synovial fluid from diffusing into the bone phase from the cartilage phase when subjected to dynamic compressive load.
A coating composition comprising: an emulsified latex polymer comprising a reaction product of ingredients including an ethylenically unsaturated monomer component polymerized in the presence of an aqueous dispersion of an emulsifying polymer having a number average molecular weight (Mn) of 8,500 to 50,000, wherein a cured film of the coating composition has a glass transition temperature (Tg) of at least 40°C, and wherein the coating composition is substantially free of each of bisphenol A, bisphenol F, and bisphenol S, including epoxides thereof. an emulsified latex polymer comprising a reaction product of ingredients including an ethylenically unsaturated monomer component polymerized in the presence of an aqueous dispersion of an emulsifying polymer having a number average molecular weight (Mn) of 8,500 to 50,000, wherein a cured film of the coating composition has a glass transition temperature (Tg) of at least 40°C, and wherein the coating composition is substantially free of each of bisphenol A, bisphenol F, and bisphenol S, including epoxides thereof.
Suction nozzle for a portable hard surface suction appliance for squeegeeing and suctioning liquid from a hard surface , in particular from a window pane , comprising a suction nozzle housing in which a suction channel that is connectable to a source of vacuum is arranged and on the housing face side of which an elastically deformable squeegee lip and an elastically deformable support lip are arranged, which protrude out of the suction nozzle housing and between which a suction space is defined, which is adjoined by the suction channel , wherein the squeegee lip comprises at its front end region protruding out of the suction nozzle housing a squeegee lip edge which is able to abut against the hard surface to be cleaned, and wherein the support lip comprises at its front end region protruding out of the suction nozzle housing a support lip edge which is able to abut against the hard surface to be cleaned, wherein the squeegee lip edge is arranged behind the support lip edge in relation to a squeegeeing direction of the suction nozzle , and the support lip comprises at least one perforation, and wherein the squeegee lip comprises a longitudinal portion projecting forwards from the housing face side in the direction pointing away from the suction channel , characterized in that the longitudinal portion of the squeegee lip , projecting forwards from the housing face side in the direction pointing away from the suction channel , is adjoined by at least one squeegee lip protrusion which in the undeformed basic position of the squeegee lip is inclined relative to the longitudinal portion and which forms a squeegee lip edge at its free end.
A system for improving security of a device comprising: - a message authentication code (MAC) generator configured to generate a first MAC based on a first authentication key and a second MAC based on a second authentication key; and - a mixing unit that is configured to: generate the first authentication key for a first segment of data, the first authentication key being the output of a mixing function applied to a first ciphertext corresponding with the first segment of data; and generate the second authentication key for a second segment of data, the second authentication key being the output of the mixing function applied to a second ciphertext corresponding with the second segment of data; wherein the first authentication key is different from the second authentication key; and wherein the mixing function is a XOR tree mixing function in which input bits (A1, A2, A3, ...) are used to select corresponding subkeys (K1, K2, K3, ...) to be XORed, and further comprises a final scrambling step making the construction non-linear, the scrambling step being comprised of rotate-add operations or a series of nonlinear S-box operations. - a message authentication code (MAC) generator configured to generate a first MAC based on a first authentication key and a second MAC based on a second authentication key; and - a mixing unit that is configured to: generate the first authentication key for a first segment of data, the first authentication key being the output of a mixing function applied to a first ciphertext corresponding with the first segment of data; and generate the second authentication key for a second segment of data, the second authentication key being the output of the mixing function applied to a second ciphertext corresponding with the second segment of data; wherein the first authentication key is different from the second authentication key; and wherein the mixing function is a XOR tree mixing function in which input bits (A1, A2, A3, ...) are used to select corresponding subkeys (K1, K2, K3, ...) to be XORed, and further comprises a final scrambling step making the construction non-linear, the scrambling step being comprised of rotate-add operations or a series of nonlinear S-box operations. generate the first authentication key for a first segment of data, the first authentication key being the output of a mixing function applied to a first ciphertext corresponding with the first segment of data; and generate the second authentication key for a second segment of data, the second authentication key being the output of the mixing function applied to a second ciphertext corresponding with the second segment of data; wherein the first authentication key is different from the second authentication key; and wherein the mixing function is a XOR tree mixing function in which input bits (A1, A2, A3, ...) are used to select corresponding subkeys (K1, K2, K3, ...) to be XORed, and further comprises a final scrambling step making the construction non-linear, the scrambling step being comprised of rotate-add operations or a series of nonlinear S-box operations.