A compound of formula (I), or the tautomers or pharmacologically acceptable acid addition salts thereof, wherein R 3 is H or C 1 -C 4 -alkoxy; R 4 is H or C 1 -C 4 -alkoxy; X is Cl or Br; and Z - is chloride, bromide, iodide, hydroxide, hydrogensulfate, sulfate, nitrate, phosphate, formate, acetate, trifluoroacetate, fumarate, citrate, tartrate, oxalate, succinate, mandelate, methanesulfonate or p-toluenesulfonate; wherein at least one of R 1 and R 2 is independently selected from a group of formula (A), wherein n is 1, 2 or 3, and R a and R b are independently selected from H, C 1 -C 4 -alkyl, wherein C 1 -C 4 -alkyl in the aforementioned moiety may carry a substituent selected from amino, C 1 -C 4 -alkylamino, di(C 1 -C 4 -alkyl)amino, hydroxy, C 1 -C 4 -alkoxy, C 1 -C 4 -alkoxycarbonylamino-, and C 1 -C 4 -alkoxycarbonyl(C 1 -C 4 -alkyl)amino-, or a 5- to 7-membered heterocycle containing 1 or 2 heteroatoms selected from O and N, wherein the 5- to 7-membered heterocycle may carry one substituent selected from C 1 -C 4 -alkyl and C 1 -C 4 -alkoxycarbonyl-; or wherein R a and R b together with the nitrogen they are attached to form a 5- to 7-membered heterocycle containing 1 or 2 heteroatoms selected from O and N, wherein the 5-to 7-membered heterocyclyl may carry one substituent selected from C 1 -C 4 -alkyl, amino, C 1 -C 4 -alkylamino, di(C 1 -C 4 -alkyl)amino, hydroxy, C 1 -C 4 -alkoxy, and C 1 -C 4 -alkoxycarbonyl-; the remaining substituent R 1 or R 2 may additionally be selected from C 1 -C 3 -alkyl, ω-fluoro-C 2 -C 3 -alkyl, 2-propenyl, dimethylaminocarbonylmethyl, and dimethylaminocarbonylpropyl. R 3 is H or C 1 -C 4 -alkoxy; R 4 is H or C 1 -C 4 -alkoxy; X is Cl or Br; and Z - is chloride, bromide, iodide, hydroxide, hydrogensulfate, sulfate, nitrate, phosphate, formate, acetate, trifluoroacetate, fumarate, citrate, tartrate, oxalate, succinate, mandelate, methanesulfonate or p-toluenesulfonate; n is 1, 2 or 3, and R a and R b are independently selected from H, C 1 -C 4 -alkyl, wherein C 1 -C 4 -alkyl in the aforementioned moiety may carry a substituent selected from amino, C 1 -C 4 -alkylamino, di(C 1 -C 4 -alkyl)amino, hydroxy, C 1 -C 4 -alkoxy, C 1 -C 4 -alkoxycarbonylamino-, and C 1 -C 4 -alkoxycarbonyl(C 1 -C 4 -alkyl)amino-, or a 5- to 7-membered heterocycle containing 1 or 2 heteroatoms selected from O and N, wherein the 5- to 7-membered heterocycle may carry one substituent selected from C 1 -C 4 -alkyl and C 1 -C 4 -alkoxycarbonyl-; or wherein R a and R b together with the nitrogen they are attached to form a 5- to 7-membered heterocycle containing 1 or 2 heteroatoms selected from O and N, wherein the 5-to 7-membered heterocyclyl may carry one substituent selected from C 1 -C 4 -alkyl, amino, C 1 -C 4 -alkylamino, di(C 1 -C 4 -alkyl)amino, hydroxy, C 1 -C 4 -alkoxy, and C 1 -C 4 -alkoxycarbonyl-; wherein C 1 -C 4 -alkyl in the aforementioned moiety may carry a substituent selected from amino, C 1 -C 4 -alkylamino, di(C 1 -C 4 -alkyl)amino, hydroxy, C 1 -C 4 -alkoxy, C 1 -C 4 -alkoxycarbonylamino-, and C 1 -C 4 -alkoxycarbonyl(C 1 -C 4 -alkyl)amino-, or a 5- to 7-membered heterocycle containing 1 or 2 heteroatoms selected from O and N, wherein the 5- to 7-membered heterocycle may carry one substituent selected from C 1 -C 4 -alkyl and C 1 -C 4 -alkoxycarbonyl-; or wherein R a and R b together with the nitrogen they are attached to form a 5- to 7-membered heterocycle containing 1 or 2 heteroatoms selected from O and N, wherein the 5-to 7-membered heterocyclyl may carry one substituent selected from C 1 -C 4 -alkyl, amino, C 1 -C 4 -alkylamino, di(C 1 -C 4 -alkyl)amino, hydroxy, C 1 -C 4 -alkoxy, and C 1 -C 4 -alkoxycarbonyl-; <EOS>