mhurhangee/patent-ind-claim-en huggingface dataset:
A composition for use in treating a disease selected from the group consisting of cardiovascular disease and Tangier disease, the composition consisting of a mixture of a plasmid vector encoding an active form of ATP-binding cassette transporter A1 (ABCA1) and sonochemically-active microspheres in a pharmaceutically acceptable aqueous carrier; wherein the vector comprises an expressible open reading frame encoding the active form of ABCA1 and at least one sequence adapted to promote expression of the open reading frame in a mammalian cell; and wherein the sonochemically-active microspheres comprise gas bubbles encapsulated within shells comprising a protein, a lipid, or a combination thereof, the microspheres being disruptable upon exposure to ultrasonic acoustic energy to release the encapsulated gas bubbles. the composition consisting of a mixture of a plasmid vector encoding an active form of ATP-binding cassette transporter A1 (ABCA1) and sonochemically-active microspheres in a pharmaceutically acceptable aqueous carrier; wherein the vector comprises an expressible open reading frame encoding the active form of ABCA1 and at least one sequence adapted to promote expression of the open reading frame in a mammalian cell; and wherein the sonochemically-active microspheres comprise gas bubbles encapsulated within shells comprising a protein, a lipid, or a combination thereof, the microspheres being disruptable upon exposure to ultrasonic acoustic energy to release the encapsulated gas bubbles.
A method for managing communication in network flows between endpoints over a network with a packet traffic management device, PTMD, wherein the PTMD includes a proxy data path and a standard data path for communicating network traffic to an endpoint; the method comprising: buffering on the PTMD network traffic from at least one unclassified network flow for which applicable network policies have not been determined ; determining at least one network policy that is associated with the at least one network flow based on at least a portion of the buffered data; when the at least one network policy includes at least one proxy policy rule, selecting the proxy data path for association with the at least one network flow , the PTMD acting as an intermediary for the at least one network flow when associated with the proxy data path to manipulate the network flow before it is communicated to the endpoint; when the at least one network policy includes only one or more standard policy rules, selecting the standard data path for association with the at least one network flow , the at least one network flow when associated with the standard data path flowing unbroken through the PTMD; and when the proxy data path or the standard data path have been selected communicating the network traffic from the at least one network flow on the network to the endpoint over the selected one of the proxy data path or the standard data path until the at least one network flow is terminated. buffering on the PTMD network traffic from at least one unclassified network flow for which applicable network policies have not been determined ; determining at least one network policy that is associated with the at least one network flow based on at least a portion of the buffered data; when the at least one network policy includes at least one proxy policy rule, selecting the proxy data path for association with the at least one network flow , the PTMD acting as an intermediary for the at least one network flow when associated with the proxy data path to manipulate the network flow before it is communicated to the endpoint; when the at least one network policy includes only one or more standard policy rules, selecting the standard data path for association with the at least one network flow , the at least one network flow when associated with the standard data path flowing unbroken through the PTMD; and when the proxy data path or the standard data path have been selected communicating the network traffic from the at least one network flow on the network to the endpoint over the selected one of the proxy data path or the standard data path until the at least one network flow is terminated.
A gas generator comprising a pyrotechnical propelling charge, wherein the charge is formed from a first and at least a second master batch which are in a mixed state in a filling, each master batch having a plurality of molded propellant bodies having defined geometry and having a relative quickness, wherein the relative quickness RQ 2 of the second master batch is less than the relative quickness RQ 1 of the first master batch, wherein RQ 2 = RQ 1 · fq and fq ≤ 0.9, wherein the molded propellant bodies in the first and second master batches as well as optionally in each further master batch have the same composition regarding the propellant components and wherein the geometry of the molded propellant bodies within one single master batch is equal but is different from the geometry of the molded propellant bodies within the respective other master batches, wherein the respective relative quickness RQ is determined by testing a sample of 10 g of the respective propelling charge or master batch in a standard combustion chamber, wherein the standard combustion chamber is a closable vessel made from steel having a volume of 100 cm 3 , wherein the sample is ignited at room temperature within the standard combustion chamber by means of a pyrotechnical igniter and the increase in pressure during the propellant burn-off is detected by means of a piezo sensor having a scanning rate of 20 kHz so that it results in a pressure/time curve which is evaluated to determine the relative quickness RQ, and wherein the evaluation is based on the first derivation dp/dt of the pressure/time curve and the function values are established at the supporting points at 0.2, 0.3, 0.4, 0.5, 0.6, 0.7 and 0.8 p/p max of the first derivation and the mean value of the function values established at the supporting points corresponds to the respective relative quickness RQ.
Compound, which binds to αvβ6 integrin, represented by the following general formula (I): Cyclo − Arg − X 1 − Asp − X 2 − X 3 − X 4 − X 5 − X 6 − X 7 wherein the variables groups X 1 to X 7 have the following meanings X 1 : Gly, X 2 : Leu, Ile, Nle, Val, Phe, X 3 : Ala, X 4 : Leu, Ile, Nle, Val, Phe, Lys, Tyr, Trp, X 5 : D-Pro, N-Me-D-Lys X 6 : Pro, N-Me-Amino acids, N-Me-Lys, N-Me-Lys(Ac), and X 7 : Ala, Leu, Ile, Nle, Val, Phe, Tyr, Trp or wherein the sub-sequence -X 5 -X 6 - represents a β-turn mimetic differing from the meanings above, or pharmaceutically acceptable salts, esters, solvates, polymorphs or modified forms thereof represented by the following general formula (II): X 0 n 1 L X 8 n 2 wherein X 0 represents the compound of the general formula (I) as specified above (excluding one hydrogen atom to allow bonding to the linker), L represents a linker, X 8 represents the effector moiety and wherein n1 and n2 are each independently selected from the range of 1 to 5, preferably such that each of n1 and n2 represents 1, wherein n1+n2 represents the number of valencies of the linker and is preferably in the range of from 2 to 6, more preferably 2-5. X 1 : Gly, X 2 : Leu, Ile, Nle, Val, Phe, X 3 : Ala, X 4 : Leu, Ile, Nle, Val, Phe, Lys, Tyr, Trp, X 5 : D-Pro, N-Me-D-Lys X 6 : Pro, N-Me-Amino acids, N-Me-Lys, N-Me-Lys(Ac), and X 7 : Ala, Leu, Ile, Nle, Val, Phe, Tyr, Trp
An anti-reflection coating comprising first to ninth layers (21-29) laminated in this order on a substrate for having reflectance of 0.2% or less to light in a visible wavelength range of 390-720 nm, said second, fourth, sixth and eighth layers being high-refractive-index layers each formed by a high-refractive-index material having a refractive index of 2.21-2.70 to a helium d-line having a wavelength of 587.56 nm; said first, third, fifth and seventh layers being intermediate-refractive-index layers each formed by an intermediate-refractive-index material having a refractive index of 1.40 or more and less than 1.55 to said d-line; and said ninth layer being a low-refractive-index layer formed by a low-refractive-index material having a refractive index of 1.35 or more and less than 1.40 to said d-line.
Diaphragm for a hydraulically damping bearing , which has a first leg , a second leg and a base connecting the two legs to one another, characterized in that the base is U-shaped with a uniform thickness and the legs project from the U-shaped base , an average thickness of one of the legs being at least twice as thick as that of the other leg , wherein the cross-section of the leg , which is on average at least twice as thick, widens continuously starting from the base , wherein the leg , which is on average at least twice as thick, has a first length (L1 ) and the other leg has a second length (L2), wherein the first length (L1 ) is at least twice as great as the second length (L2), wherein the leg , which is on average at least twice as thick, forms the radially outer leg.
A polyolefin grafted polydiene polymer comprising: a polydiene having a polydiene polymer backbone; a polyolefin having an anhydride polymeric modifier; and at least one sulfur containing functionalizing agent which grafts the polyolefin onto at least one non-terminal position on the polydiene polymer backbone. a polydiene having a polydiene polymer backbone; a polyolefin having an anhydride polymeric modifier; and at least one sulfur containing functionalizing agent which grafts the polyolefin onto at least one non-terminal position on the polydiene polymer backbone.
A probiotic preparation comprising viable, metabolically active probiotic bacteria in a non-dairy liquid substrate, for use in the treatment of Irritable Bowel Syndrome, wherein the probiotic preparation comprises a mixture of Lactobacillus plantarum, Lactobacillus acidophilus, and either Lactobacillus casei or Lactobacillus rhamnosus or both Lactobacillus casei and Lactobacillus rhamnosus.
Apparatus comprising a vessel and a chemical feed distributor passing therein, the chemical feed distributor comprising: a chemical feed inlet that passes a chemical feed stream into the chemical feed distributor , the chemical feed stream consisting of a first portion and a second portion ; a body comprising one or more walls and a plurality of primary chemical feed outlets , wherein the one or more walls define an elongated chemical feed stream flow path , wherein the plurality of primary chemical feed outlets are spaced along at least a portion of the length of the elongated chemical feed stream flow path , and wherein the plurality of primary chemical feed outlets are arranged to pass the first portion of the chemical feed stream out of the feed distributor and into the vessel ; and a secondary chemical feed outlet downstream of the plurality of primary chemical feed outlets , wherein the secondary chemical feed outlet is arranged to pass the second portion of the chemical feed stream out of the chemical feed distributor such that the second portion of the chemical feed stream is passed through the chemical feed distributor and does not enter the vessel . a chemical feed inlet that passes a chemical feed stream into the chemical feed distributor , the chemical feed stream consisting of a first portion and a second portion ; a body comprising one or more walls and a plurality of primary chemical feed outlets , wherein the one or more walls define an elongated chemical feed stream flow path , wherein the plurality of primary chemical feed outlets are spaced along at least a portion of the length of the elongated chemical feed stream flow path , and wherein the plurality of primary chemical feed outlets are arranged to pass the first portion of the chemical feed stream out of the feed distributor and into the vessel ; and a secondary chemical feed outlet downstream of the plurality of primary chemical feed outlets , wherein the secondary chemical feed outlet is arranged to pass the second portion of the chemical feed stream out of the chemical feed distributor such that the second portion of the chemical feed stream is passed through the chemical feed distributor and does not enter the vessel .
A pharmaceutical composition for oral administration, comprising a phosphate binder, said phosphate binder comprises particles having a particle size distribution, wherein at least 40 % of the particles have a particle size within the range of 4 to 200 μm, d50 is in the range of between 40 μm to 100 μm, and wherein the phosphate binder particles comprise a mixture of iron(III)-oxyhydroxide, sucrose and one or more starches, which pharmaceutical composition is a compressed tablet or a chewable tablet.
A computer implemented method for compiling a computer language, the method comprising: detecting (S202), according to a preset syntax, whether an incorrect syntax unit exists in a to-be-compiled statement, wherein the to-be-compiled statement has an associated syntax tree having at least one parent node and at least one child node, the child node being either a mandatory node or an optional node of the respective parent node, wherein the to-be-compiled statement is an illegal statement without a mandatory node and is a correct statement without an optional node; determining (S204) whether a child node at which the syntax unit is located is an optional node of a corresponding parent node, in response to determining that the incorrect syntax unit exists in the to-be compiled statement; and deleting (S206) the syntax unit, in response to determining that the child node at which the syntax unit is located is the optional node of the corresponding parent node. detecting (S202), according to a preset syntax, whether an incorrect syntax unit exists in a to-be-compiled statement, wherein the to-be-compiled statement has an associated syntax tree having at least one parent node and at least one child node, the child node being either a mandatory node or an optional node of the respective parent node, wherein the to-be-compiled statement is an illegal statement without a mandatory node and is a correct statement without an optional node; determining (S204) whether a child node at which the syntax unit is located is an optional node of a corresponding parent node, in response to determining that the incorrect syntax unit exists in the to-be compiled statement; and deleting (S206) the syntax unit, in response to determining that the child node at which the syntax unit is located is the optional node of the corresponding parent node.
A laundry treating apparatus comprising: a rear support , a first laundry treating drum and a condensation drying module, wherein a rear end of the first laundry treating drum is installed on the rear support , and the first laundry treating drum is in communication with the condensation drying module; the condensation drying module comprises a base and a condenser , and the rear support is provided with an opening for allowing the condenser to be inserted and installed into the base ; characterized in that the laundry treating apparatus is provided with a second laundry treating drum under the first laundry treating drum , and the base is installed between the first laundry treating drum and the second laundry treating drum .
A detector assembly including: a semiconductor detector having a first surface and a second surface opposed to each other, the first surface including pixels containing pixelated anodes, and the second surface comprising a cathode electrode; a pinhole collimator including an array of pinhole openings corresponding to the pixels, wherein the pinhole collimator is arranged to cause each of the pixels of the semiconductor to receive radiation only via a single pinhole opening of the pinhole collimator, wherein the area of each pinhole opening is smaller than a corresponding radiation receiving area of the corresponding pixels; and a processing unit operably coupled to the semiconductor detector and configured to identify detected events within virtual sub-pixels distributed along a length and width of the semiconductor detector, wherein each pixel comprises a plurality of corresponding virtual sub-pixels, wherein absorbed photons of the radiation are counted as events in a corresponding virtual sub-pixel. a semiconductor detector having a first surface and a second surface opposed to each other, the first surface including pixels containing pixelated anodes, and the second surface comprising a cathode electrode; a pinhole collimator including an array of pinhole openings corresponding to the pixels, wherein the pinhole collimator is arranged to cause each of the pixels of the semiconductor to receive radiation only via a single pinhole opening of the pinhole collimator, wherein the area of each pinhole opening is smaller than a corresponding radiation receiving area of the corresponding pixels; and a processing unit operably coupled to the semiconductor detector and configured to identify detected events within virtual sub-pixels distributed along a length and width of the semiconductor detector, wherein each pixel comprises a plurality of corresponding virtual sub-pixels, wherein absorbed photons of the radiation are counted as events in a corresponding virtual sub-pixel.
An ophthalmic composition comprising: atropine or a pharmaceutically acceptable salt thereof; and a miotic agent selected from the group consisting of brimonidine, bunazosin, thymoxamine, apraclonidine, phentolamine, combinations thereof, or pharmaceutically acceptable salts thereof. atropine or a pharmaceutically acceptable salt thereof; and a miotic agent selected from the group consisting of brimonidine, bunazosin, thymoxamine, apraclonidine, phentolamine, combinations thereof, or pharmaceutically acceptable salts thereof.
An introducer for facilitating placement of an implantable monitor, the introducer comprising: a body portion ; and an indicator cooperating with the body portion and configured to indicate at least one of width, depth, and position for an arrangement of the implantable monitor relative to a patient, wherein the indicator is configured to sense an impedance measurement of the patient and indicate the position for the arrangement of the implantable monitor in response thereto. a body portion ; and an indicator cooperating with the body portion and configured to indicate at least one of width, depth, and position for an arrangement of the implantable monitor relative to a patient, wherein the indicator is configured to sense an impedance measurement of the patient and indicate the position for the arrangement of the implantable monitor in response thereto.
A method of resistance spot welding in which a sheet combination of two or more overlapping steel sheets is sandwiched between a pair of electrodes and joined together by applying current while applying pressure, the method comprising: a main current application step in which current application is performed with a current I w , kA; and subsequently, a post-tempering heat treatment step in which after cooling is performed for a cooling time t ct , ms, shown in formula below, current application is performed with a current I t , kA, shown in formula below for a current application time tt, ms, shown in formula below, wherein at least one steel sheet in the sheet combination has a composition containing 0.08 ≤ C ≤ 0.3 ,% by mass, 0.1 ≤ Si ≤ 0.8 ,% by mass, 2.5 ≤ Mn ≤ 10.0 ,% by mass, and P ≤ 0.1 ,% by mass, with the balance being Fe and unavoidable impurities: 800 ≤ t ct 0.5 × I w ≤ I t ≤ I w and 500 ≤ t t the method being characterised by further comprising, between the main current application step and the post-tempering heat treatment step: a post-segregation reduction heat treatment step in which after cooling is performed for a cooling time t cp , ms, shown in formula below, current application is performed with a current I p , kA, shown in formula below for a current application time t p , ms, shown in formula below: 10 ≤ t cp 0.6 × I w ≤ I p ≤ 0.99 × I w and 400 ≤ t p a main current application step in which current application is performed with a current I w , kA; and subsequently, a post-tempering heat treatment step in which after cooling is performed for a cooling time t ct , ms, shown in formula below, current application is performed with a current I t , kA, shown in formula below for a current application time tt, ms, shown in formula below, wherein at least one steel sheet in the sheet combination has a composition containing 0.08 ≤ C ≤ 0.3 ,% by mass, 0.1 ≤ Si ≤ 0.8 ,% by mass, 2.5 ≤ Mn ≤ 10.0 ,% by mass, and P ≤ 0.1 ,% by mass, with the balance being Fe and unavoidable impurities: 800 ≤ t ct 0.5 × I w ≤ I t ≤ I w and 500 ≤ t t the method being characterised by further comprising, between the main current application step and the post-tempering heat treatment step: a post-segregation reduction heat treatment step in which after cooling is performed for a cooling time t cp , ms, shown in formula below, current application is performed with a current I p , kA, shown in formula below for a current application time t p , ms, shown in formula below: 10 ≤ t cp 0.6 × I w ≤ I p ≤ 0.99 × I w and 400 ≤ t p
Aqueous writing, marking and/or drawing fluid for capillary systems, in particular for applicators with a capillary system, which has a viscosity of less than 50 mPas, in particular less than 20 mPas (Brookfield, 20 °C, cone-plate CPE-40), containing a wetting agent, graphite having a carbon content between 95 and 99.9 wt.%, an ash content between 0.1 and 5 wt.% and a particle size ≤ 20 μm at D90, and at least one release agent, in particular in a concentration of 2 to 15 wt.%, wherein barium sulfate and/or an aqueous, low-viscosity, non-sedimenting colloidal dispersion of nano-particulate silica particles is contained as a release agent.
Medical material containing foam mass composition consisting of a mixture of dibutyrylchitin and polylactide wherein surface mass is 208 g/m 2 , test liquid A absorbency is C A = 12.748 g liquid /g sample and free water sorption in time t=8h is 10.600 g liquid /g sample and wherein foam mass composition is obtained by mixing a PLA solution in acetone of 5% w/w concentration with a DBC solution in acetone of a 5% w/w concentration with addition of a plasticizer which is glycerol in the amount of 5% w/w as related to the polymer mixture solution mass and a blowing agent which is solid sodium chloride in the amount of 150% w/w as related to polymer mixture solution mass.
Geothermal probe comprising at least one probe tube , an inner tube cavity of the probe tube being filled with a two-phase heat transfer fluid , and a wall of the probe tube surrounding the inner tube cavity comprising at least one circumferentially closed diffusion barrier layer consisting of metal and at least one jacket layer consisting of plastics material sheathing the diffusion barrier layer on the outside, characterised in that the diffusion barrier layer and the jacket layer are glued to one another, preferably directly, and in that the probe tube has a surface tension on the inner surface thereof delimiting the inner tube cavity for wetting the inner surface with heat transfer fluid , which surface tension is equal to or greater than the surface tension of the heat transfer fluid in the liquid state.