A compound, being a compound represented by Formula (I); or being a stereoisomer, geometric isomer, tautomer, nitrogen oxide, hydrate, solvate, or pharmaceutically acceptable salt of the compound represented by Formula (I): wherein X 1 and X 2 are independently C(R 7a ) 2 ; wherein R 1 is H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b , -C(=O)OR 7b , -OC(=O)R 7b , -C(=O)NR 8a R 8b , - NR 8 C(=O)R 7b , R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b , R 7b S(=O) 2 -, C 6-10 aryl, or heteroaryl consisting of 5-12 atoms, wherein one, two, three, four or five carbon atoms of the C 6-10 aryl or heteroaryl consisting of 5-12 atoms are independently and optionally substituted with R 10 , wherein R 10 is each independently H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b , -C(=O)OR 7b , -OC(=O)R 7b , -C(=O)NR 8a R 8b , -NR 8 C(=O)R 7b , R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b , or R 7b S(=O) 2 -; wherein R 2 is -C(=O)R 7c , -C(=O)(C(R 7a ) 2 ) n1 R 7c , -C(=O)OR 7c , -OC(=O)R 7c , - C(=O)NR 8a R 8b , -C(=S)NR 8a R 8b , -NR 8 C(=O)R 7c , R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7c , or R 7c S(=O) 2 -; wherein R 3 is H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, oxo, or C 1-6 alkyl; wherein R 4 , R 5 , and R 6 are each independently H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, or C 1-6 alkyl; wherein R 7a , R 7b , R 7c , R 8 , R 8a , and R 8b are each independently H, D, F, Cl, Br, I, -CN, - NO 2 , -OH, -NH 2 , -COOH, C 1-6 alkyl, or C 1-6 halogenated alkyl; and wherein m1, m2, and n1 are independently 0, 1, 2, 3, or 4. wherein X 1 and X 2 are independently C(R 7a ) 2 ; wherein R 1 is H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b , -C(=O)OR 7b , -OC(=O)R 7b , -C(=O)NR 8a R 8b , - NR 8 C(=O)R 7b , R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b , R 7b S(=O) 2 -, C 6-10 aryl, or heteroaryl consisting of 5-12 atoms, wherein one, two, three, four or five carbon atoms of the C 6-10 aryl or heteroaryl consisting of 5-12 atoms are independently and optionally substituted with R 10 , wherein R 10 is each independently H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, C 3-8 cycloalkyl, C 1-6 halogenated alkyl, C 1-6 hydroxyl-substituted alkyl, C 1-6 alkoxyl, C 1-6 halogenated alkoxyl, -C(=O)R 7b , -C(=O)OR 7b , -OC(=O)R 7b , -C(=O)NR 8a R 8b , -NR 8 C(=O)R 7b , R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7b , or R 7b S(=O) 2 -; wherein R 2 is -C(=O)R 7c , -C(=O)(C(R 7a ) 2 ) n1 R 7c , -C(=O)OR 7c , -OC(=O)R 7c , - C(=O)NR 8a R 8b , -C(=S)NR 8a R 8b , -NR 8 C(=O)R 7c , R 8a R 8b N-S(=O) 2 -, -R 8 N-S(=O) 2 R 7c , or R 7c S(=O) 2 -; wherein R 3 is H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, oxo, or C 1-6 alkyl; wherein R 4 , R 5 , and R 6 are each independently H, D, F, Cl, Br, I, -CN, -NO 2 , -OH, -NH 2 , -COOH, or C 1-6 alkyl; wherein R 7a , R 7b , R 7c , R 8 , R 8a , and R 8b are each independently H, D, F, Cl, Br, I, -CN, - NO 2 , -OH, -NH 2 , -COOH, C 1-6 alkyl, or C 1-6 halogenated alkyl; and wherein m1, m2, and n1 are independently 0, 1, 2, 3, or 4. <EOS>