mhurhangee/patent-ind-claim-en huggingface dataset:
A composition comprising an effective amount of aVEGFR3 agonist, which has at least 85% sequence identity to VEGF-c or VEGF-d, for use in a method of treating a neurodegenerative disease in the central nervous system of a subject, the method comprising: determining the subject to be in need of treatment of a neurodegenerative disease in the central nervous system; and administering an effective amount of the VEGFR3 agonist to a meningeal space of the subject in need, whereby said administration is effective to increase the diameter of a meningeal lymphatic vessel of the subject, thereby increasing fluid flow in the central nervous system of the subject. determining the subject to be in need of treatment of a neurodegenerative disease in the central nervous system; and administering an effective amount of the VEGFR3 agonist to a meningeal space of the subject in need, whereby said administration is effective to increase the diameter of a meningeal lymphatic vessel of the subject, thereby increasing fluid flow in the central nervous system of the subject.
A method of monitoring the covering of a mold surface of a mold using an auxiliary process agent in a casting process, wherein the casting process comprises a process step of applying the auxiliary process agent to the mold surface of the mold and at least one process step of filling the mold with a material, characterized in that at least one infrared image of the mold surface is recorded after the application of the auxiliary process agent and/or before the filling of the mold in a spectral range of a characteristic absorption band of the auxiliary process agent , with the covering of the mold surface with the auxiliary process agent being determined with reference to the contribution of the infrared absorption of the auxiliary process agent to the infrared image, and with the fact being utilized that the contribution of the infrared absorption of the auxiliary process agent generates a contrast in the infrared image between zones of the mold surface with an applied auxiliary process agent and such zones at which the auxiliary process agent layer is not present or is too thin.
Method for monitoring an installation comprising at least one robot, in particular a plurality of robots , comprising the following steps: - monitoring (S50) a distance region (A10; A20) of at least one robot of the installation; and - transferring (S70) said robot into a safe state on the basis of a detection (S20) of a position of at least one person within said distance region, characterized by the following steps: - performing (S70) a work process of the robot until an interruption point that is predefined, in particular beforehand and/or in a process-dictated manner and/or automatically or by an operator; and - interrupting (S70) the work process, in particular stopping the robot, in particular without interrupting its power supply, and/or deactivating at least one, in particular robot-guided, tool, at said interruption point, - the distance region being predefined on the basis of a work time until an interruption point, in particular a maximum work time between two interruption points and/or a work time until a next interruption point in the work process. - monitoring (S50) a distance region (A10; A20) of at least one robot of the installation; and - transferring (S70) said robot into a safe state on the basis of a detection (S20) of a position of at least one person within said distance region, characterized by the following steps: - performing (S70) a work process of the robot until an interruption point that is predefined, in particular beforehand and/or in a process-dictated manner and/or automatically or by an operator; and - interrupting (S70) the work process, in particular stopping the robot, in particular without interrupting its power supply, and/or deactivating at least one, in particular robot-guided, tool, at said interruption point, - the distance region being predefined on the basis of a work time until an interruption point, in particular a maximum work time between two interruption points and/or a work time until a next interruption point in the work process.
A partial peptide, a composition containing the partial peptide, or a cancer vaccine composition comprising DNA or RNA encoding the partial peptide, for use in cancer treatment or prevention in HLA-A*0206-positive persons, wherein the partial peptide is (a) a modified peptide of the WT1 187 peptide consisting of the sequence Ser Leu Gly Glu Gln Gln Tyr Ser Val of SEQ ID NO: 2 comprising substitution of one or two amino acid residues in the amino acid sequence of the WT1 187 peptide and the same amino acid residues at positions 4 to 8 from the N terminus as the WT1 187 peptide has at the corresponding positions, which is immunogenic in HLA-A*0206-positive persons, or (b) a modified peptide of the WT1 126 peptide consisting of the sequence Arg Met Phe Pro Asn Ala Pro Tyr Leu of SEQ ID NO: 3 comprising substitution of one or two amino acid residues in the amino acid sequence of the WT1 126 peptide and the same amino acid residues at positions 4 to 8 from the N terminus as the WT1 126 peptide has at the corresponding positions, which is immunogenic in HLA-A*0206-positive persons. (a) a modified peptide of the WT1 187 peptide consisting of the sequence Ser Leu Gly Glu Gln Gln Tyr Ser Val of SEQ ID NO: 2 comprising substitution of one or two amino acid residues in the amino acid sequence of the WT1 187 peptide and the same amino acid residues at positions 4 to 8 from the N terminus as the WT1 187 peptide has at the corresponding positions, which is immunogenic in HLA-A*0206-positive persons, or (b) a modified peptide of the WT1 126 peptide consisting of the sequence Arg Met Phe Pro Asn Ala Pro Tyr Leu of SEQ ID NO: 3 comprising substitution of one or two amino acid residues in the amino acid sequence of the WT1 126 peptide and the same amino acid residues at positions 4 to 8 from the N terminus as the WT1 126 peptide has at the corresponding positions, which is immunogenic in HLA-A*0206-positive persons.
Method of operating a user equipment in a radio access network, the method comprising transmitting acknowledgement signaling according to a HARQ codebook at a second HARQ transmitting occasion, the HARQ codebook indicating first acknowledgement information, the first acknowledgement information pertaining to first data signaling scheduled to be received by the user equipment before a first HARQ transmitting occasion that occurred earlier in time than the second HARQ transmitting occasion, characterised in that the HARQ codebook comprises also second acknowledgement information pertaining to data signaling scheduled to be received later in time than the first HARQ transmitting occasion and in that the first acknowledgement information pertaining to the first data signaling represents leftover HARQ bits for the which the determination process took too long to be included in a HARQ feedback transmitted during the first HARQ transmission occasion.
An engine system comprising: - an internal combustion engine (ICE); - a turbocharger (TC) comprising a compressor (C) and a turbine (T); - a supply line (L) that provides air to the engine (ICE) through said compressor (C); said supply line (L) comprising a supplementary compression stage distinct from said compressor (C); control means being provided for controlling said supplementary compression stage and for adjusting said turbine (T), in order to limit the back pressure of the exhaust gases exiting said engine, in a combined manner with the control of said supplementary compression stage; characterised in that said supplementary compression stage comprises an ejector (E) connected to a pressurised air source (S) and arranged downstream of said compressor (C) so as to receive air from said source (S) and cause, in use, a depression that sucks air out of said compressor (C); and whereby the engine system further comprising a heater for heating air that flows, in use, from said source (S) to said ejector (E). - an internal combustion engine (ICE); - a turbocharger (TC) comprising a compressor (C) and a turbine (T); - a supply line (L) that provides air to the engine (ICE) through said compressor (C); said supply line (L) comprising a supplementary compression stage distinct from said compressor (C); control means being provided for controlling said supplementary compression stage and for adjusting said turbine (T), in order to limit the back pressure of the exhaust gases exiting said engine, in a combined manner with the control of said supplementary compression stage; characterised in that said supplementary compression stage comprises an ejector (E) connected to a pressurised air source (S) and arranged downstream of said compressor (C) so as to receive air from said source (S) and cause, in use, a depression that sucks air out of said compressor (C); and whereby the engine system further comprising a heater for heating air that flows, in use, from said source (S) to said ejector (E).
A method of treating the skin or hair on a dog containing an effective amount of an ectoparasiticide previously applied to the skin or hair, the method comprising applying a quantity of a cleansing composition directly to the skin or hair, wherein the treatment does not result in reducing the efficacy of the ectoparasiticide against adult fleas ( C. felis ) or adult ticks ( R. sanguineus ) below 90% efficacy for at least a month after application of the ectoparasiticide; wherein the cleansing composition comprises 1-3 % glycerin by weight of the total composition, 2-4% silicone copolyol esters by weight of the total composition, and water, and wherein the cleansing composition comprises less than 0.5 % by weight of surfactant by weight of the total composition.
Method for determining a reference value of a presence of at least one substance occurring in an exhaust gas stream of an internal combustion engine , wherein the at least one substance is subjected to exhaust treatment, the exhaust treatment being carried out in dependence of the reference value ( Em ref ; Em ref, 1 ; Em ref, 2 ) , the method being characterised in that when the internal combustion engine is started and the start of the internal combustion engine fulfils a first criterion: accumulating the occurrence of the at least one substance downstream the exhaust treatment during a first period, wherein the criterion comprises a criterion which is used to determine whether the start of the internal combustion engine is to be classified as a cold start or not, and determining whether to redetermine the reference value ( Em ref ; Em ref, 1 ; Em ref,2 ) based on the accumulated occurrence ( Em ACC, 1 ; Em ACC, 2 ) of the at least one substance, and redetermining the reference value ( Em ref ; Em ref, 1 ; Em ref,2 ) when the accumulated occurrence ( Em ACC, 1 ; Em ACC, 2 ) of said at least one substance exceeds a first limit. accumulating the occurrence of the at least one substance downstream the exhaust treatment during a first period, wherein the criterion comprises a criterion which is used to determine whether the start of the internal combustion engine is to be classified as a cold start or not, and determining whether to redetermine the reference value ( Em ref ; Em ref, 1 ; Em ref,2 ) based on the accumulated occurrence ( Em ACC, 1 ; Em ACC, 2 ) of the at least one substance, and redetermining the reference value ( Em ref ; Em ref, 1 ; Em ref,2 ) when the accumulated occurrence ( Em ACC, 1 ; Em ACC, 2 ) of said at least one substance exceeds a first limit.
A combustor for a turbine engine , the combustor comprising: a combustor wall including a shell and a heat shield attached to the shell ; wherein: one or more cooling cavities are defined between the shell and the heat shield , and fluidly couple a plurality of apertures defined in the shell with a plurality of apertures defined in the heat shield ; the apertures in the heat shield include a first aperture and a second aperture ; the first aperture is one of a plurality of first apertures defined in the heat shield , and a density of the first apertures in a first region of the heat shield is greater than a density of the first apertures in a second region of the heat shield ; the second aperture is one of a plurality of second apertures defined in the heat shield , and a density of the second apertures in the first region is less than a density of the second apertures in the second region of the heat shield ; each first aperture extends along a respective centerline , and the centerline is offset from a combustion chamber surface by a first included angle that is equal to thirty degrees (30°); and each second aperture extends along a respective centerline , and the centerline is offset from the combustion chamber surface by a second included angle that is between zero (0°) and twenty-five degrees (25°). one or more cooling cavities are defined between the shell and the heat shield , and fluidly couple a plurality of apertures defined in the shell with a plurality of apertures defined in the heat shield ; the apertures in the heat shield include a first aperture and a second aperture ; the first aperture is one of a plurality of first apertures defined in the heat shield , and a density of the first apertures in a first region of the heat shield is greater than a density of the first apertures in a second region of the heat shield ; the second aperture is one of a plurality of second apertures defined in the heat shield , and a density of the second apertures in the first region is less than a density of the second apertures in the second region of the heat shield ; each first aperture extends along a respective centerline , and the centerline is offset from a combustion chamber surface by a first included angle that is equal to thirty degrees (30°); and each second aperture extends along a respective centerline , and the centerline is offset from the combustion chamber surface by a second included angle that is between zero (0°) and twenty-five degrees (25°).
Device for packaging a cosmetic product in the form of a stick, in particular lipstick, having: - a distributor mechanism , having a proximal part and a rotary distal part , configured such that the rotary movement of the distal part with respect to the proximal part is accompanied by an axial movement of the stick relative to the proximal part, - a case having a body made of, in particular transparent, mineral glass, in which said mechanism can be fitted and secured, the glass body having a neck and the case having a ring made of thermoplastic material which is attached and secured to the neck and to which said mechanism is secured. - a distributor mechanism , having a proximal part and a rotary distal part , configured such that the rotary movement of the distal part with respect to the proximal part is accompanied by an axial movement of the stick relative to the proximal part, - a case having a body made of, in particular transparent, mineral glass, in which said mechanism can be fitted and secured, the glass body having a neck and the case having a ring made of thermoplastic material which is attached and secured to the neck and to which said mechanism is secured.
An unbalance detection method for a front-loading washing machine, comprising the following steps of: A. during an accelerative operation of a drum according to a constant acceleration: - detecting (S1) a torque of the drum and acquiring a torque average value in a period of per rotation that the drum completes; - once the drum completes one rotation at the beginning of the accelerative operation, setting (S1) the acquired torque average value of that rotation as a minimum torque average value; - when the drum completes another one rotation and another torque average value is acquired, comparing the another acquired torque average value with the minimum torque average value, and updating the minimum torque average value according to the comparison; and B. judging (S2) whether a difference value between the torque average value and the minimum torque average value is greater than a preset unbalance threshold value, and if the difference value is greater than the preset unbalance threshold value, determining (S3) that dynamic unbalance appears in the drum, otherwise determining (S4) that no dynamic unbalance appears in the drum. A. during an accelerative operation of a drum according to a constant acceleration: - detecting (S1) a torque of the drum and acquiring a torque average value in a period of per rotation that the drum completes; - once the drum completes one rotation at the beginning of the accelerative operation, setting (S1) the acquired torque average value of that rotation as a minimum torque average value; - when the drum completes another one rotation and another torque average value is acquired, comparing the another acquired torque average value with the minimum torque average value, and updating the minimum torque average value according to the comparison; and B. judging (S2) whether a difference value between the torque average value and the minimum torque average value is greater than a preset unbalance threshold value, and - detecting (S1) a torque of the drum and acquiring a torque average value in a period of per rotation that the drum completes; - once the drum completes one rotation at the beginning of the accelerative operation, setting (S1) the acquired torque average value of that rotation as a minimum torque average value; - when the drum completes another one rotation and another torque average value is acquired, comparing the another acquired torque average value with the minimum torque average value, and updating the minimum torque average value according to the comparison; and B. judging (S2) whether a difference value between the torque average value and the minimum torque average value is greater than a preset unbalance threshold value, and
A method for controlling an inverter in an inverter system, wherein the inverter includes a rectifier , a direct current-link capacitor , and an inverting unit including a plurality of switching elements, wherein the inverter system includes a control unit for controlling the inverting unit, wherein the method comprises: checking, by the control unit , whether a direct current-link voltage of the direct current-link capacitor is equal to or greater than a predefined first voltage; checking, by the control unit , whether the direct current-link voltage is greater than or equal to a predefined second voltage greater than the predefined first voltage; calculating, by the control unit , a value (V 2 t) which is derived by multiplying the square of the direct current-link voltage (V) and a unit time (t), wherein the unit time (t) indicates time required for an overvoltage fault to occur based on the direct current-link voltage, and generating, by the control unit , a cumulative value by accumulating the calculated value when the direct current-link voltage is greater than or equal to the predefined first voltage and is smaller than the predefined second voltage; when the cumulative value is greater than or equal to a predefined first value, blocking, by the control unit , an output of the inverting unit; and when the direct current-link voltage is smaller than the predefined first voltage, obtaining, by the control unit , a value by subtracting a predefined second value from the cumulative value, and updating, by the control unit , the cumulative value as the obtained value. checking, by the control unit , whether a direct current-link voltage of the direct current-link capacitor is equal to or greater than a predefined first voltage; checking, by the control unit , whether the direct current-link voltage is greater than or equal to a predefined second voltage greater than the predefined first voltage; calculating, by the control unit , a value (V 2 t) which is derived by multiplying the square of the direct current-link voltage (V) and a unit time (t), wherein the unit time (t) indicates time required for an overvoltage fault to occur based on the direct current-link voltage, and generating, by the control unit , a cumulative value by accumulating the calculated value when the direct current-link voltage is greater than or equal to the predefined first voltage and is smaller than the predefined second voltage; when the cumulative value is greater than or equal to a predefined first value, blocking, by the control unit , an output of the inverting unit; and when the direct current-link voltage is smaller than the predefined first voltage, obtaining, by the control unit , a value by subtracting a predefined second value from the cumulative value, and updating, by the control unit , the cumulative value as the obtained value.
A method comprising: obtaining channel access after a clear channel assessment, CCA, operation ; determining an offset between a boundary of a symbol and a particular time at which the channel access is obtained ; generating a channel reservation, CR, preamble based on the offset , generating a CR message payload indicating reservations and/or availability of multiple beam directions; wherein the generating the CR preamble includes partitioning the CR preamble into a plurality of segments, each segment comprising a different waveform for identification as a CR preamble and identification of a particular symbol at which to expect the CR message; and wherein the plurality of segments comprises a first segment having a fixed duration, a second segment having a variable duration, and a third segment having a fixed duration; and transmitting the CR preamble and the CR message. obtaining channel access after a clear channel assessment, CCA, operation ; determining an offset between a boundary of a symbol and a particular time at which the channel access is obtained ; generating a channel reservation, CR, preamble based on the offset , generating a CR message payload indicating reservations and/or availability of multiple beam directions; wherein the generating the CR preamble includes partitioning the CR preamble into a plurality of segments, each segment comprising a different waveform for identification as a CR preamble and identification of a particular symbol at which to expect the CR message; and wherein the plurality of segments comprises a first segment having a fixed duration, a second segment having a variable duration, and a third segment having a fixed duration; and wherein the generating the CR preamble includes partitioning the CR preamble into a plurality of segments, each segment comprising a different waveform for identification as a CR preamble and identification of a particular symbol at which to expect the CR message; and wherein the plurality of segments comprises a first segment having a fixed duration, a second segment having a variable duration, and a third segment having a fixed duration; and transmitting the CR preamble and the CR message.
A medicament comprising (A) and (B), wherein (A) is a compound selected from the below III-1 and II-4: and wherein (B) is selected from Oseltamivir, Zanamivir, Peramivir, Laninamivir and VX-787; and wherein either: (i) (B) is Oseltamivir, and the medicament is for use in the treatment or prevention of influenza strain A/WSN/33 (H1N1), A/PR/8/34 (H1N1), A/Victoria/3/75 (H3N2) or A/HongKong/8/68 (H3N2); or (ii) (B) is Peramivir, Laninamivir or Zanamivir, and the medicament is for use in the treatment or prevention of influenza strain A/PR/8/34 (H1N1); or (iii) (B) is VX-787, and the medicament is for use in the treatment or prevention of influenza strain A/PR/8/34 (H1N1). (i) (B) is Oseltamivir, and the medicament is for use in the treatment or prevention of influenza strain A/WSN/33 (H1N1), A/PR/8/34 (H1N1), A/Victoria/3/75 (H3N2) or A/HongKong/8/68 (H3N2); or (ii) (B) is Peramivir, Laninamivir or Zanamivir, and the medicament is for use in the treatment or prevention of influenza strain A/PR/8/34 (H1N1); or (iii) (B) is VX-787, and the medicament is for use in the treatment or prevention of influenza strain A/PR/8/34 (H1N1).