mhurhangee/patent-ind-claim-en huggingface dataset:
A method for detecting lysosomal enzyme (LE)-specific neutralizing factors in a sample comprising the steps of: (a) contacting a body fluid sample with a lysosomal enzyme conjugated to a detection moiety to detect LE-specific neutralizing factors in the body fluid sample, wherein the LE-specific neutralizing factor and lysosomal enzyme detection moiety form a complex; (b) contacting the LE-specific factor/lysosomal enzyme complex from step (a) with cells comprising a cation independent mannose-6-phosphate receptor (CI-MPR), wherein the sample is contacted with the cells for at least three hours at approximately 37°C; and (c) detecting the presence of LE-specific neutralizing factor from the body fluid sample by detecting the presence of the lysosomal enzyme labeled with the detection moiety inside the cell or on the surface of the cell, wherein the limit of detection is less than about 500 ng/mL. (a) contacting a body fluid sample with a lysosomal enzyme conjugated to a detection moiety to detect LE-specific neutralizing factors in the body fluid sample, wherein the LE-specific neutralizing factor and lysosomal enzyme detection moiety form a complex; (b) contacting the LE-specific factor/lysosomal enzyme complex from step (a) with cells comprising a cation independent mannose-6-phosphate receptor (CI-MPR), wherein the sample is contacted with the cells for at least three hours at approximately 37°C; and (c) detecting the presence of LE-specific neutralizing factor from the body fluid sample by detecting the presence of the lysosomal enzyme labeled with the detection moiety inside the cell or on the surface of the cell, wherein the limit of detection is less than about 500 ng/mL.
A computer-implemented method, comprising: receiving , by a computing device , wireless connection information via a notification from a broker device , the wireless connection information including multiple wireless channels for wireless communication with a wireless device ; utilizing , by the computing device , the wireless connection information to directly communicate data wirelessly with the wireless device independent of a separate access point to manage the wireless communication; storing , by the computing device , the wireless connection information for the wireless device locally in a table on the computing device , said table comprising at least a resource identifier column and a channel column, said resource identifier column including identifiers for resources, and said channel column specifying wireless channels at which respective resources can be found, wherein resources correspond to devices, and wherein at least some of the wireless channels are associated with more than one resource in the table; and establishing, by the computing device a subsequent direct wireless communication session with the wireless device using the locally stored wireless connection information, wherein a different channel is assigned for use by a particular resource if the channel identified for the resource is currently in use by another resource, said different channel selected from multiple channels associated with the resource in the table. receiving , by a computing device , wireless connection information via a notification from a broker device , the wireless connection information including multiple wireless channels for wireless communication with a wireless device ; utilizing , by the computing device , the wireless connection information to directly communicate data wirelessly with the wireless device independent of a separate access point to manage the wireless communication; storing , by the computing device , the wireless connection information for the wireless device locally in a table on the computing device , said table comprising at least a resource identifier column and a channel column, said resource identifier column including identifiers for resources, and said channel column specifying wireless channels at which respective resources can be found, wherein resources correspond to devices, and wherein at least some of the wireless channels are associated with more than one resource in the table; and establishing, by the computing device a subsequent direct wireless communication session with the wireless device using the locally stored wireless connection information, wherein a different channel is assigned for use by a particular resource if the channel identified for the resource is currently in use by another resource, said different channel selected from multiple channels associated with the resource in the table.
A method for improving detection accuracy of cognitive dysfunction diseases comprising: measuring simultaneously or separately the following biomarkers (a), (b), and (c) for detecting cognitive dysfunction diseases in a biological sample from a subject: (a) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of apolipoprotein A1 comprising the amino acid sequence represented by SEQ ID NO: 1 or a partial peptide thereof; (b) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of transthyretin comprising the amino acid sequence represented by SEQ ID NO: 2 or a partial peptide thereof; and (c) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of complement C3 comprising the amino acid sequence represented by SEQ ID NO: 3 or a partial peptide thereof; wherein the method comprises: measuring the (c) biomarker and the (a) biomarker when the cognitive dysfunction disease is mild cognitive impairment, or measuring the (c) biomarker and the (b) biomarker when the cognitive dysfunction disease is Alzheimer's disease. (a) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of apolipoprotein A1 comprising the amino acid sequence represented by SEQ ID NO: 1 or a partial peptide thereof; (b) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of transthyretin comprising the amino acid sequence represented by SEQ ID NO: 2 or a partial peptide thereof; and (c) a biomarker for detecting cognitive dysfunction diseases consisting of an intact protein of complement C3 comprising the amino acid sequence represented by SEQ ID NO: 3 or a partial peptide thereof; wherein the method comprises: measuring the (c) biomarker and the (a) biomarker when the cognitive dysfunction disease is mild cognitive impairment, or measuring the (c) biomarker and the (b) biomarker when the cognitive dysfunction disease is Alzheimer's disease. measuring the (c) biomarker and the (a) biomarker when the cognitive dysfunction disease is mild cognitive impairment, or measuring the (c) biomarker and the (b) biomarker when the cognitive dysfunction disease is Alzheimer's disease.
An electronic module containing a multilayer PCB circuit and one or more electronic components that are electrically connected to said multilayer PCB circuit that comprises, on one face, electrical connection balls for the external electrical connection of the electronic module, the PCB circuit comprising a hermetically protective electrically insulating inorganic inner layer , characterised in that the module comprises six faces with an electrically insulating or conductive inorganic hermetic protection layer entirely covering the five faces other than that formed by the PCB circuit and in that the hermetically protective electrically insulating inorganic inner layer is in direct contact with the electrically insulating or conductive inorganic hermetic protection layer , so as to form a hermetic seal around the one or more electronic components .
Electronic distance meter comprising a laser emitting a laser pulse toward a target , a photodetector adapted for receiving a laser pulse reflected by the target and for outputting a corresponding return pulse signal, and a comparison circuit receiving said return pulse signal and comprising a comparator provided with a first input and a second input and arranged to output a first fixed value signal when the signal at the first input exceeds the signal at the second input and else to output a second fixed value signal, said comparison circuit being arranged for determining a return pulse time signal based on the output of said comparator , said electronic distance meter being arranged for determining a target distance based on said return pulse time signal, wherein said comparison circuit comprises a first branch connected to said first input and provided with an integrator which receives a signal derived from said return pulse signal and comprises an output connected to said first input , and a second branch connected to said second input which receives a signal derived from one or more transforms of said return pulse signal said one or more transforms being chosen in the group comprising identity, voltage offset and voltage amplification.
A method for obtaining an object in general comprising the phases of: - Realization of a base structure of the object in polystyrene; - Distribution of a first polyurethane material onto at least a part of said base structure so as to create a rigid shell which confers predetermined structural features to the said base structure, said first polyurethane material being a compact rigid polyurethane material; - Characterized by the fact of comprising a phase of realization of a coating (A+B; 400A+400B) which coats at least in part said rigid shell, said phase of realization of the coating comprising a distribution onto said at least one part of rigid shell of a second type of polyurethane material or, alternatively, the realization of one or more preformed blocks (A1, A2) made of said second type of polyurethane material and joined to said base structure, said second type of polyurethane material being an expanded polyurethane material which forms an external layer overlapping said rigid shell, said external layer being realized with an increased thickness; - Subsequent machining by means of machine tools of said external layer of expanded polyurethane material so as to bring the object to the final size; - And wherein said phase of realization of the base structure comprises a machining of one or more blocks of polystyrene by means of machine tools according to a predetermined shape or, alternatively, a mould casting. - Realization of a base structure of the object in polystyrene; - Distribution of a first polyurethane material onto at least a part of said base structure so as to create a rigid shell which confers predetermined structural features to the said base structure, said first polyurethane material being a compact rigid polyurethane material; - Characterized by the fact of comprising a phase of realization of a coating (A+B; 400A+400B) which coats at least in part said rigid shell, said phase of realization of the coating comprising a distribution onto said at least one part of rigid shell of a second type of polyurethane material or, alternatively, the realization of one or more preformed blocks (A1, A2) made of said second type of polyurethane material and joined to said base structure, said second type of polyurethane material being an expanded polyurethane material which forms an external layer overlapping said rigid shell, said external layer being realized with an increased thickness; - Subsequent machining by means of machine tools of said external layer of expanded polyurethane material so as to bring the object to the final size; - And wherein said phase of realization of the base structure comprises a machining of one or more blocks of polystyrene by means of machine tools according to a predetermined shape or, alternatively, a mould casting.
A water-soluble paint composition for vehicle, the water-soluble paint composition comprising a core-shell microgel resin, a dimer-modified polyester resin, a (meth)acryl-modified polyurethane resin, a curing agent, a pigment, and water, wherein the dimer-modified polyester resin is comprised in an amount of 1 to 10 wt% with respect to 100 wt% of the water-soluble paint composition.
A pitch bearing of a wind turbine , configured to be connected to a blade , comprising: an inner bearing ring , an outer bearing ring and an extension portion , one of the inner bearing ring and the outer bearing ring is integrally formed with the extension portion ; and wherein the pitch bearing further comprises a plurality of pins , which are integrally formed with the extension portion and are configured to connect the blade root of the blade . an inner bearing ring , an outer bearing ring and an extension portion , one of the inner bearing ring and the outer bearing ring is integrally formed with the extension portion ; and wherein the pitch bearing further comprises a plurality of pins , which are integrally formed with the extension portion and are configured to connect the blade root of the blade .
Solenoid valve for an internal combustion engine with: - a housing , - a coil , - an armature which can be moved axially by energizing the coil , - a sliding bush which is received in a bore of the housing - a tappet configuring a valve body, which is movable with the armature - a compression spring which applies a force to the tappet in opposition to an electromagnetic force acting on the tappet characterized in that the compression spring surrounds the slide bushing and is guided through the slide bushing , and the housing is configured in two parts, the slide bushing being arranged in a first housing part and a coil carrier and the armature being arranged in a second housing part and in that the first housing part is mechanically connected to the second housing part , wherein the compression spring bears against a shoulder of the first housing part and against the tappet . - a housing , - a coil , - an armature which can be moved axially by energizing the coil , - a sliding bush which is received in a bore of the housing - a tappet configuring a valve body, which is movable with the armature - a compression spring which applies a force to the tappet in opposition to an electromagnetic force acting on the tappet characterized in that
A vehicle part cover comprising a methacrylic-based resin (I) having a weight average molecular weight measured by gel permeation chromatography (GPC) of 65,000 to 300,000 and a weight loss ratio of 5% or less when held for 30 minutes at 290°C measured according to setting conditions defined in the description, the methacrylic-based resin (I) comprising: 50 to 97% by mass of a methacrylate monomer unit (A); 3 to 30% by mass of a structural unit (B) having a ring structure in its main chain, and being at least one selected from the group consisting of a maleimide-based structural unit, a glutarimide-based structural unit, and a lactone ring structural unit; and 0 to 20% by mass of another vinyl monomer unit (C) that is copolymerizable with a methacrylate monomer, wherein the vehicle part cover has a thickness of 0.1 to 5 mm and is: a vehicle instrument cover selected from the group consisting of a vehicle clock cover, an indicator cover, a combination meter cover, a meter cover, and a vehicle head-up display, or a vehicle rear lamp cover selected from the group consisting of a tail lamp cover, a rear combination lamp cover, and a high mount stop lamp cover. 50 to 97% by mass of a methacrylate monomer unit (A); 3 to 30% by mass of a structural unit (B) having a ring structure in its main chain, and being at least one selected from the group consisting of a maleimide-based structural unit, a glutarimide-based structural unit, and a lactone ring structural unit; and 0 to 20% by mass of another vinyl monomer unit (C) that is copolymerizable with a methacrylate monomer, wherein the vehicle part cover has a thickness of 0.1 to 5 mm and is: a vehicle instrument cover selected from the group consisting of a vehicle clock cover, an indicator cover, a combination meter cover, a meter cover, and a vehicle head-up display, or a vehicle rear lamp cover selected from the group consisting of a tail lamp cover, a rear combination lamp cover, and a high mount stop lamp cover. a vehicle instrument cover selected from the group consisting of a vehicle clock cover, an indicator cover, a combination meter cover, a meter cover, and a vehicle head-up display, or a vehicle rear lamp cover selected from the group consisting of a tail lamp cover, a rear combination lamp cover, and a high mount stop lamp cover.
A method of operating a first infrastructure equipment forming part of a wireless communications network comprising a plurality of other infrastructure equipment , the first infrastructure equipment being an integrated access and backhaul, IAB, node which is configured to communicate with at least two of the plurality of other infrastructure equipment via a backhaul communications link within a system bandwidth, the plurality of other infrastructure equipment each being IAB nodes, one or more of the first infrastructure equipment and the plurality of other infrastructure equipment each being configured to communicate with one or more communications devices via an access link within the system bandwidth, wherein the system bandwidth comprises a plurality of bandwidth parts, each of the bandwidth parts being formed of a contiguous set of frequency resources that is smaller than and within the system bandwidth, the method comprising transmitting radio signals to and/or receiving radio signals from a second of the infrastructure equipment using frequency resources of a first of the bandwidth parts, the first infrastructure equipment being a parent node to the second infrastructure equipment and configured to allocate communications resources to the second infrastructure equipment, and transmitting radio signals to and/or receiving radio signals from a third of the infrastructure equipment using frequency resources of a second of the bandwidth parts, the first infrastructure equipment being a child node of the third infrastructure equipment and configured to receive allocated communications resources from the third infrastructure equipment, wherein the frequency resources of the first bandwidth part are distinct from and do not overlap with the frequency resources of the second bandwidth part. transmitting radio signals to and/or receiving radio signals from a second of the infrastructure equipment using frequency resources of a first of the bandwidth parts, the first infrastructure equipment being a parent node to the second infrastructure equipment and configured to allocate communications resources to the second infrastructure equipment, and transmitting radio signals to and/or receiving radio signals from a third of the infrastructure equipment using frequency resources of a second of the bandwidth parts, the first infrastructure equipment being a child node of the third infrastructure equipment and configured to receive allocated communications resources from the third infrastructure equipment, wherein the frequency resources of the first bandwidth part are distinct from and do not overlap with the frequency resources of the second bandwidth part.
A method of forming a transaction card having a laser-treatable layer for personalization of the card and a hard coat layer thereover, with an energy absorbing buffer layer between the laser-treatable layer and the hard coat layer, the method being characterized by the steps of: forming a core subassembly (A, A1, C, D, E, F) comprising two or more layers including the laser-treatable layer and comprising one or more elements defining the functionality of the card; said first core subassembly having a top layer and a bottom layer; forming a hard coat subassembly (B) including the hard coat layer attached to a release layer mounted on a carrier layer; attaching the hard coat subassembly (B) to the top layer of the core subassembly so the hard coat layer is closest to the core subassembly, and disposing the buffer layer between the core subassembly and the hard coat layer, to form a first card assembly; laminating the first card assembly under predetermined temperature and pressure; and removing the release layer and the carrier layer to form a resultant card. forming a core subassembly (A, A1, C, D, E, F) comprising two or more layers including the laser-treatable layer and comprising one or more elements defining the functionality of the card; said first core subassembly having a top layer and a bottom layer; forming a hard coat subassembly (B) including the hard coat layer attached to a release layer mounted on a carrier layer; attaching the hard coat subassembly (B) to the top layer of the core subassembly so the hard coat layer is closest to the core subassembly, and disposing the buffer layer between the core subassembly and the hard coat layer, to form a first card assembly; laminating the first card assembly under predetermined temperature and pressure; and removing the release layer and the carrier layer to form a resultant card.
A substituted bis(trifluorovinyl)benzene compound represented by general formula : wherein R 1 to R 4 each independently represent a hydrogen atom, a methyl group, an ethyl group, a linear or branched alkyl group having 3 to 4 carbon atoms, a fluorine-containing alkyl group having 1 to 2 carbon atoms, a fluorine-containing linear or branched alkyl group having 3 to 4 carbon atoms, a fluorine-containing alkenyl group having 2 to 3 carbon atoms, a methoxy group, an ethoxy group, a linear or branched alkoxy group having 3 to 4 carbon atoms, a fluorine-containing alkyl group having 1 to 2 carbon atoms, a fluorine-containing linear or branched alkoxy group having 3 to 4 carbon atoms, or a halogen atom, provided that R 1 to R 4 are not all hydrogen atoms; and one or both of ortho positions of the benzene ring to a trifluorovinyl group is substituted with a methyl group, an ethyl group, a linear or branched alkyl group having 3 to 4 carbon atoms, a fluorine-containing alkyl group having 1 to 2 carbon atoms, a fluorine-containing linear or branched alkyl group having 3 to 4 carbon atoms, a fluorine-containing alkenyl group having 2 to 3 carbon atoms, a methoxy group, an ethoxy group, a linear or branched alkoxy group having 3 to 4 carbon atoms, a fluorine-containing alkoxy group having 1 to 2 carbon atoms, a fluorine-containing linear or branched alkoxy group having 3 to 4 carbon atoms, or a halogen atom.
A system for analyzing a sample using variable mass selection window widths, comprising: a tandem mass spectrometer that includes a mass analyzer, and a processor in communication with the tandem mass spectrometer; characterized in that : the mass analyzer allows variable mass selection window widths across a mass range of a sample; and the processor is configured to instruct the tandem mass spectrometer to perform at least two fragmentation scans of at least two variable mass selection window widths with different mass selection window widths across the mass range of the sample in a single scan of the mass range. a tandem mass spectrometer that includes a mass analyzer, and a processor in communication with the tandem mass spectrometer; the mass analyzer allows variable mass selection window widths across a mass range of a sample; and the processor is configured to instruct the tandem mass spectrometer to perform at least two fragmentation scans of at least two variable mass selection window widths with different mass selection window widths across the mass range of the sample in a single scan of the mass range.