mhurhangee/patent-ind-claim-en huggingface dataset:
A method of separating at least one target biomolecule species from a biological sample, comprising: (a) in a reaction mixture, contacting a biological sample known or suspected to contain first and second biomolecule species of interest with a targeted magnetic particle species that targets the first biomolecule species of interest to form first target biomolecule/magnetic particle complexes, and a targeted buoyant particle species, that targets the second biomolecule species of interest to form second target biomolecule/buoyant particle complexes, wherein the targeted magnetic particle species is a targeted nanomagnetic particle species that comprises: (i) a magnetic core particle; (ii) a glass layer encapsulating the magnetic core particle; (iii) a protein/polymer composite layer bound to the glass layer; and (iv) a targeting moiety that targets the first biomolecule species of interest and comprises one member of a bioaffinity ligand pair bound to the protein/polymer composite layer; (b) after (a), separating the second target biomolecule/buoyant particle complexes from the reaction mixture using buoyancy/floatation properties, thereby depleting the reaction mixture of the second biomolecule species; and, (c) after (b), isolating the first biomolecule/magnetic particle complexes from the reaction mixture using a magnetic field. (a) in a reaction mixture, contacting a biological sample known or suspected to contain first and second biomolecule species of interest with a targeted magnetic particle species that targets the first biomolecule species of interest to form first target biomolecule/magnetic particle complexes, and a targeted buoyant particle species, that targets the second biomolecule species of interest to form second target biomolecule/buoyant particle complexes, wherein the targeted magnetic particle species is a targeted nanomagnetic particle species that comprises: (i) a magnetic core particle; (ii) a glass layer encapsulating the magnetic core particle; (iii) a protein/polymer composite layer bound to the glass layer; and (iv) a targeting moiety that targets the first biomolecule species of interest and comprises one member of a bioaffinity ligand pair bound to the protein/polymer composite layer; (i) a magnetic core particle; (ii) a glass layer encapsulating the magnetic core particle; (iii) a protein/polymer composite layer bound to the glass layer; and (iv) a targeting moiety that targets the first biomolecule species of interest and comprises one member of a bioaffinity ligand pair bound to the protein/polymer composite layer; (b) after (a), separating the second target biomolecule/buoyant particle complexes from the reaction mixture using buoyancy/floatation properties, thereby depleting the reaction mixture of the second biomolecule species; and, (c) after (b), isolating the first biomolecule/magnetic particle complexes from the reaction mixture using a magnetic field.
A process to manufacture lignin-based polyols, which comprises: a) Dissolving lignin and an acidic catalyst in an organic solvent or a mixture thereof; b) Adjusting the temperature of the solution obtained in step a) at a value from -15 °C to 60 °C under stirring; c) Adding continuously an oxirane or a solution of an oxirane in an organic solvent or a mixture thereof, on the solution obtained in step b) at a flow rate from 0.01 to 1.0 L-oxirane/h/kg-lignin, d) Keeping the reaction mixture obtained in step c) after addition completion for an appropriate time; e) Neutralizing the catalyst by adding an appropriate amount of a base on the reaction mixture obtained in step d); and f) Isolating the lignin-based polyols from the mixture obtained in step e). a) Dissolving lignin and an acidic catalyst in an organic solvent or a mixture thereof; b) Adjusting the temperature of the solution obtained in step a) at a value from -15 °C to 60 °C under stirring; c) Adding continuously an oxirane or a solution of an oxirane in an organic solvent or a mixture thereof, on the solution obtained in step b) at a flow rate from 0.01 to 1.0 L-oxirane/h/kg-lignin, d) Keeping the reaction mixture obtained in step c) after addition completion for an appropriate time; e) Neutralizing the catalyst by adding an appropriate amount of a base on the reaction mixture obtained in step d); and f) Isolating the lignin-based polyols from the mixture obtained in step e).
Apparatus comprising: housing, the housing comprising a first body part and a second body part , the first body part being moveable relative to the second body part , wherein the housing has a first configuration when the first body part is in a first position relative to the second body part and a second configuration when the first body part is in a second position relative to the second body part ; and a speaker arrangement, wherein the speaker arrangement comprises: transducer means , a front cavity coupled to a first side of the transducer means , and an opening configured to connect the front cavity to an exterior of the housing, and a rear cavity coupled to a second side of the transducer means , the second side of the transducer means being an opposite side of the transducer means to the first side of the transducer means , characterised in that the speaker arrangement having a first physical arrangement when the housing is in the first configuration and a second physical arrangement when the housing is in the second configuration, the first physical arrangement being different to the second physical arrangement, wherein the apparatus is configured such that an area of the opening when the housing is in the first configuration is greater than the area of the opening when the housing is in the second configuration, a change in the area of the opening resulting from a change in dimensions of the opening as the housing moves between the first and second configuration. housing, the housing comprising a first body part and a second body part , the first body part being moveable relative to the second body part , wherein the housing has a first configuration when the first body part is in a first position relative to the second body part and a second configuration when the first body part is in a second position relative to the second body part ; and a speaker arrangement, wherein the speaker arrangement comprises: transducer means , a front cavity coupled to a first side of the transducer means , and an opening configured to connect the front cavity to an exterior of the housing, and transducer means , a front cavity coupled to a first side of the transducer means , and an opening configured to connect the front cavity to an exterior of the housing, and a rear cavity coupled to a second side of the transducer means , the second side of the transducer means being an opposite side of the transducer means to the first side of the transducer means , characterised in that the speaker arrangement having a first physical arrangement when the housing is in the first configuration and a second physical arrangement when the housing is in the second configuration, the first physical arrangement being different to the second physical arrangement, wherein the apparatus is configured such that an area of the opening when the housing is in the first configuration is greater than the area of the opening when the housing is in the second configuration, a change in the area of the opening resulting from a change in dimensions of the opening as the housing moves between the first and second configuration.
A gear box assembly comprising: an outer housing ; a gear box shaft at least partially disposed in the outer housing, the gear box shaft comprising: an interior region having two volumes defined therein, the two volumes including a reservoir volume and a spline volume , the reservoir volume defined by a reservoir torus formed during rotation of the gear box shaft and having a height (Rh) and the spline volume defined by a spline torus formed during rotation of the gear box shaft and having a height (Sh) different than the height (Rh) of the reservoir volume; and a reservoir dam in the interior region that separates the interior region into the reservoir volume and the spline volume ; and one or more gear box shaft venting holes formed through the gear box shaft near an end thereof; and a circular regulator disposed at least partially within the gear box shaft, the regulator including a base , a tubular side wall extending from the base and one or more regulator vent holes , wherein at least one of the regulator venting holes is in fluid communication with one of the one or more gear box shaft vent holes. an outer housing ; a gear box shaft at least partially disposed in the outer housing, the gear box shaft comprising: an interior region having two volumes defined therein, the two volumes including a reservoir volume and a spline volume , the reservoir volume defined by a reservoir torus formed during rotation of the gear box shaft and having a height (Rh) and the spline volume defined by a spline torus formed during rotation of the gear box shaft and having a height (Sh) different than the height (Rh) of the reservoir volume; and a reservoir dam in the interior region that separates the interior region into the reservoir volume and the spline volume ; and one or more gear box shaft venting holes formed through the gear box shaft near an end thereof; and a circular regulator disposed at least partially within the gear box shaft, the regulator including a base , a tubular side wall extending from the base and one or more regulator vent holes , wherein at least one of the regulator venting holes is in fluid communication with one of the one or more gear box shaft vent holes. an interior region having two volumes defined therein, the two volumes including a reservoir volume and a spline volume , the reservoir volume defined by a reservoir torus formed during rotation of the gear box shaft and having a height (Rh) and the spline volume defined by a spline torus formed during rotation of the gear box shaft and having a height (Sh) different than the height (Rh) of the reservoir volume; and a reservoir dam in the interior region that separates the interior region into the reservoir volume and the spline volume ; and one or more gear box shaft venting holes formed through the gear box shaft near an end thereof; and a circular regulator disposed at least partially within the gear box shaft, the regulator including a base , a tubular side wall extending from the base and one or more regulator vent holes , wherein at least one of the regulator venting holes is in fluid communication with one of the one or more gear box shaft vent holes.
A cabinet structure , comprising: a wrapper spaced apart from a liner ; a trim breaker coupled to the wrapper and the liner , wherein an insulation cavity is defined between the wrapper , the liner , and the trim breaker ; and a first hinge bracket having at least one fastener inserted therethrough, the fastener being positioned externally from the insulation cavity , characterised by further comprising a first hinge support positioned laterally outward of a second hinge support , the first and second hinge supports being each coupled with the first hinge bracket proximate the trim breaker . a wrapper spaced apart from a liner ; a trim breaker coupled to the wrapper and the liner , wherein an insulation cavity is defined between the wrapper , the liner , and the trim breaker ; and a first hinge bracket having at least one fastener inserted therethrough, the fastener being positioned externally from the insulation cavity , characterised by further comprising a first hinge support positioned laterally outward of a second hinge support , the first and second hinge supports being each coupled with the first hinge bracket proximate the trim breaker .
A bone void filler material for sustained release of a therapeutic agent, the bone void filler material comprising a biodegradable matrix being a porous sponge and having ceramic cement beads comprising calcium sulfate and being biodegradable, and ceramic particles disposed within the matrix, the ceramic cement beads being loaded with the therapeutic agent to cause sustained release of the therapeutic agent.
A system for fixation of leaflets of a heart valve, the system comprising: a catheter having a proximal end and a distal end , the catheter configured to pass from remote vasculature of a patient to a location within the patient's body near the heart valve; and a fixation device removably coupleable to the distal end and having a pair of distal elements , each distal element having an engagement surface for engaging the leaflets of the heart valve, wherein the distal elements are moveable between an open position wherein the distal elements extend radially outwardly to face the engagement surfaces toward a first direction, and an inverted position wherein the distal elements have moved away from the first direction to face the engagement surfaces radially outwardly, and further wherein the distal elements are moveable between a closed position and the open position, wherein in the closed position the engagement surfaces face one another, wherein the fixation device further comprises a pair of proximal elements configured for engaging the leaflets of the heart valve between respective proximal and distal elements , wherein the proximal elements are covered with a fabric or other flexible material covering, wherein the proximal elements include barbs or other frictional features which protrude through the covering so as to contact the leaflets of the heart valve engaged by the proximal elements . a catheter having a proximal end and a distal end , the catheter configured to pass from remote vasculature of a patient to a location within the patient's body near the heart valve; and a fixation device removably coupleable to the distal end and having a pair of distal elements , each distal element having an engagement surface for engaging the leaflets of the heart valve, wherein the distal elements are moveable between an open position wherein the distal elements extend radially outwardly to face the engagement surfaces toward a first direction, and an inverted position wherein the distal elements have moved away from the first direction to face the engagement surfaces radially outwardly, and further wherein the distal elements are moveable between a closed position and the open position, wherein in the closed position the engagement surfaces face one another, wherein the fixation device further comprises a pair of proximal elements configured for engaging the leaflets of the heart valve between respective proximal and distal elements , wherein the proximal elements are covered with a fabric or other flexible material covering, wherein the proximal elements include barbs or other frictional features which protrude through the covering so as to contact the leaflets of the heart valve engaged by the proximal elements .
A hinged structure for a toilet cover plate, comprising a fixed seat fixedly arranged on the toilet and a cover plate rotatably arranged on the fixed seat , a mounting hole is arranged on the cover plate , and a seat hinge assembly for hinging the fixed seat with the cover plate is installed in the mounting hole ; the seat hinge assembly comprises an oil core sleeve fixedly arranged in the mounting hole , and the seat hinge assembly further comprises a hinge shaft , wherein the hinge shaft comprises an oil core part rotatably arranged in the oil core sleeve and a seat hinge part inserted and matched with the connection column on the fixed seat , and the oil core part is integrally formed with the seat hinge part ; the cover plate is provided with an arc-shaped hole communicated with the mounting hole at a radial direction; when the seat hinge assembly is installed in the mounting hole , the seat hinge assembly is clamped in the arc-shaped hole through an annular elastic buckle , so that the seat hinge assembly is axially fixed; a sealing cavity for containing damping oil is formed between the oil core part and the oil core sleeve ; the inner wall of the oil core sleeve is provided with a spacer block protruding radially inward, the spacer block separates the sealing cavity into a first cavity and a second cavity , and a shaft hole matched with the oil core is arranged through a middle of the spacer block , and the oil core part passes through the shaft hole and is fixedly connected with the limit column by ultrasonic welding.
External fixator for orthopedic use, in particular for the treatment of calcaneus fractures, comprising: - a first clamp for fixing bone screws; - a second clamp ; - a third clamp ; - a rigid support for the first clamp ; - a second support for the second clamp , said second support being hinged at an end of the rigid support ; - a third support for the third clamp , said third support being hinged at the end of the rigid support ; - the rigid support being configured as a guide with the first clamp slidingly mounted thereon; characterized in that the end of the rigid support for connection with the second and third supports is configured to house respective hinges having axes that are orthogonal to each other. - a first clamp for fixing bone screws; - a second clamp ; - a third clamp ; - a rigid support for the first clamp ; - a second support for the second clamp , said second support being hinged at an end of the rigid support ; - a third support for the third clamp , said third support being hinged at the end of the rigid support ; - the rigid support being configured as a guide with the first clamp slidingly mounted thereon; characterized in that the end of the rigid support for connection with the second and third supports is configured to house respective hinges having axes that are orthogonal to each other.
A vacuum pump , in particular a turbomolecular vacuum pump, comprising: a rotor having a rotor shaft ; a rotary bearing for supporting the rotor shaft ; a liquid operating medium for supplying the rotary bearing ; and an operating medium store comprising storage material suitable for storing the operating medium, wherein the storage material comprises at least two different materials (M1, M2), characterized in that the materials (M1, M2) are different felt materials which have different tendencies towards releasing individual felt fibers, wherein the felt material which is less prone to releasing the felt fibers at least partly surrounds the felt material which is more prone to releasing the felt fibers. a rotor having a rotor shaft ; a rotary bearing for supporting the rotor shaft ; a liquid operating medium for supplying the rotary bearing ; and an operating medium store comprising storage material suitable for storing the operating medium, wherein the storage material comprises at least two different materials (M1, M2), characterized in that the materials (M1, M2) are different felt materials which have different tendencies towards releasing individual felt fibers, wherein the felt material which is less prone to releasing the felt fibers at least partly surrounds the felt material which is more prone to releasing the felt fibers.
Atomizer nozzle for atomizing a fluid, in particular a liquid, with a nozzle opening , with a rotation chamber , and with at least one supply channel for supplying the fluid into the rotation chamber , wherein at least one supply channel opens into the rotation chamber via at least one inlet opening , characterized in that the rotation chamber has a curved bottom , the bottom is curved away from the nozzle opening , at least one supply channel is directed in the direction of the bottom , and at least one supply channel runs obliquely at least in sections to the plane defined by the edge of the bottom area. the rotation chamber has a curved bottom , the bottom is curved away from the nozzle opening , at least one supply channel is directed in the direction of the bottom , and at least one supply channel runs obliquely at least in sections to the plane defined by the edge of the bottom area.
A method for receiving system information, SI, by a user equipment, UE, in a wireless communication system, the method comprising: receiving (S1110), from a base station, BS, minimum SI which is broadcasted periodically, the minimum SI including information indicating whether a SI message for other SI is broadcast periodically or provisioned on demand, and configuration information on a physical random access channel, PRACH, wherein the configuration information includes information on PRACH resource for the other SI; in case that the information indicates that the SI message for the other SI is provisioned on demand, transmitting (S1120), to the BS, a PRACH preamble corresponding to the SI message based on the configuration information; and receiving (S1130), from the BS, the SI message for the other SI in response to the PRACH preamble. receiving (S1110), from a base station, BS, minimum SI which is broadcasted periodically, the minimum SI including information indicating whether a SI message for other SI is broadcast periodically or provisioned on demand, and configuration information on a physical random access channel, PRACH, wherein the configuration information includes information on PRACH resource for the other SI; in case that the information indicates that the SI message for the other SI is provisioned on demand, transmitting (S1120), to the BS, a PRACH preamble corresponding to the SI message based on the configuration information; and receiving (S1130), from the BS, the SI message for the other SI in response to the PRACH preamble.
A fluoropolymer composite comprising: a) 5 to 40, preferably 5 to 25, weight percent of sized chopped fiber; and b) a matrix comprising grafted functionalized fluoropolymer wherein the grafted fluoropolymer has been grafted with a carboxylic functionality. a) 5 to 40, preferably 5 to 25, weight percent of sized chopped fiber; and b) a matrix comprising grafted functionalized fluoropolymer wherein the grafted fluoropolymer has been grafted with a carboxylic functionality.