A dental medicament applicator comprising: a placement device sized for insertion at a dental site, the dental site being an interproximal site, the placement device including a central body , a first wing , and a second wing ; the central body having a front , a rear , an upper end , a lower end , a first lateral end , and a second lateral end ; the first wing having a proximal end and a distal end , the first wing being coupled to the first lateral end , the first wing providing subterminal opposition surfaces in which palmar surfaces of a thumb and an index finger can hold the first wing therebetween, the first wing having a transverse axis from the distal end to the proximal end , the transverse axis having a transverse length (L W1 ) greater than twice the mean width for a human tooth, the first wing being free of a topical substance for treating incipient lesions; the second wing having a proximal end and a distal end , the second wing being coupled to the second lateral end , the second wing providing subterminal opposition surfaces in which palmar surfaces of a thumb and an index finger can hold the second wing therebetween, the second wing having a transverse axis from the distal end to the proximal end, the transverse axis having a transverse length (L W2 ) greater than twice the mean width for a human tooth, the second wing being free of the topical substance; at least one active matrix secured to the front of the central body , the at least one active matrix containing the topical substance; each of the first wing and the second wing having a larger surface area than the at least one active matrix ; the placement device , in response to being physically affixed to the dental site, dissolving at a first controlled rate; and the at least one active matrix , in response to being physically affixed to the dental site, delivering the topical substance at a second controlled rate to the dental site, the second controlled rate being slower in time than the first controlled rate. a placement device sized for insertion at a dental site, the dental site being an interproximal site, the placement device including a central body , a first wing , and a second wing ; the central body having a front , a rear , an upper end , a lower end , a first lateral end , and a second lateral end ; the first wing having a proximal end and a distal end , the first wing being coupled to the first lateral end , the first wing providing subterminal opposition surfaces in which palmar surfaces of a thumb and an index finger can hold the first wing therebetween, the first wing having a transverse axis from the distal end to the proximal end , the transverse axis having a transverse length (L W1 ) greater than twice the mean width for a human tooth, the first wing being free of a topical substance for treating incipient lesions; the second wing having a proximal end and a distal end , the second wing being coupled to the second lateral end , the second wing providing subterminal opposition surfaces in which palmar surfaces of a thumb and an index finger can hold the second wing therebetween, the second wing having a transverse axis from the distal end to the proximal end, the transverse axis having a transverse length (L W2 ) greater than twice the mean width for a human tooth, the second wing being free of the topical substance; at least one active matrix secured to the front of the central body , the at least one active matrix containing the topical substance; each of the first wing and the second wing having a larger surface area than the at least one active matrix ; the placement device , in response to being physically affixed to the dental site, dissolving at a first controlled rate; and the at least one active matrix , in response to being physically affixed to the dental site, delivering the topical substance at a second controlled rate to the dental site, the second controlled rate being slower in time than the first controlled rate. <EOS>