mhurhangee/patent-ind-claim-en huggingface dataset:
A system comprising: a mobile application residing on an external device ; and an inhalation device comprising a mouthpiece , a mouthpiece cover , medicament, and an electronics module comprising a processor and a sensor ; wherein the inhalation device is configured to both prepare a dose of medicament for delivery to a user and cause the processor to transition between power states when the mouthpiece cover is moved from a closed position to an open position to expose the mouthpiece; and wherein the electronics module or the mobile application is configured to generate usage events based on feedback from the sensor or movement of the mouthpiece cover from a closed position to an open position, characterized in that the electronics module or the mobile application is configured to determine that feedback from the sensor indicates that there have been multiple inhalation events while the mouthpiece cover is in the open position, and provide a notification to the user that the mouthpiece cover needs to be closed and then re-opened to ensure that a subsequent dose of medication is made available for inhalation. a mobile application residing on an external device ; and an inhalation device comprising a mouthpiece , a mouthpiece cover , medicament, and an electronics module comprising a processor and a sensor ; wherein the inhalation device is configured to both prepare a dose of medicament for delivery to a user and cause the processor to transition between power states when the mouthpiece cover is moved from a closed position to an open position to expose the mouthpiece; and wherein the electronics module or the mobile application is configured to generate usage events based on feedback from the sensor or movement of the mouthpiece cover from a closed position to an open position, characterized in that the electronics module or the mobile application is configured to determine that feedback from the sensor indicates that there have been multiple inhalation events while the mouthpiece cover is in the open position, and provide a notification to the user that the mouthpiece cover needs to be closed and then re-opened to ensure that a subsequent dose of medication is made available for inhalation.
An antigen recognizing construct specifically binding to the amino acid sequence of SEQ ID NO: 1 in complex with a human leucocyte antigen (HLA) class I molecule, wherein said antigen recognizing construct comprises a TCR alpha variable domain and a TCR beta variable domain, or a TCR gamma variable domain and a TCR delta variable domain, and wherein (i) the TCR alpha variable domain or TCR gamma variable domain comprise the complementarity determining regions (CDRs) having the amino acid sequence of SEQ ID NO: 42, SEQ ID NO: 43 and SEQ ID NO: 44 and the TCR beta variable domain or TCR delta variable comprises the CDRs having the amino acid sequence of SEQ ID NO: 50, SEQ ID NO: 51 and SEQ ID NO: 52, or (ii) the TCR alpha variable domain or TCR gamma variable domain comprises the CDRs having the amino acid sequence of SEQ ID NO: 58, SEQ ID NO: 59 and SEQ ID NO: 60 and the TCR beta variable domain or TCR delta variable comprises the CDRs having the amino acid sequence of SEQ ID NO: 66, SEQ ID NO: 67 and SEQ ID NO: 68, or (iii) the TCR alpha variable domain or TCR gamma variable domain comprises the CDRs having the amino acid sequence of SEQ ID NO: 74, SEQ ID NO: 75 and SEQ ID NO: 76 and the TCR beta variable domain or TCR delta variable comprises the CDRs having the amino acid sequence of SEQ ID NO: 82, SEQ ID NO: 83 and SEQ ID NO: 84. (i) the TCR alpha variable domain or TCR gamma variable domain comprise the complementarity determining regions (CDRs) having the amino acid sequence of SEQ ID NO: 42, SEQ ID NO: 43 and SEQ ID NO: 44 and the TCR beta variable domain or TCR delta variable comprises the CDRs having the amino acid sequence of SEQ ID NO: 50, SEQ ID NO: 51 and SEQ ID NO: 52, or (ii) the TCR alpha variable domain or TCR gamma variable domain comprises the CDRs having the amino acid sequence of SEQ ID NO: 58, SEQ ID NO: 59 and SEQ ID NO: 60 and the TCR beta variable domain or TCR delta variable comprises the CDRs having the amino acid sequence of SEQ ID NO: 66, SEQ ID NO: 67 and SEQ ID NO: 68, or (iii) the TCR alpha variable domain or TCR gamma variable domain comprises the CDRs having the amino acid sequence of SEQ ID NO: 74, SEQ ID NO: 75 and SEQ ID NO: 76 and the TCR beta variable domain or TCR delta variable comprises the CDRs having the amino acid sequence of SEQ ID NO: 82, SEQ ID NO: 83 and SEQ ID NO: 84.
A polynucleotide encoding a chimeric antigen receptor, wherein said chimeric antigen receptor comprises an antigen binding domain, a transmembrane domain and a costimulatory signal transduction region, wherein the antigen binding domain specifically binds to the tumor specific antigen ROBO1, and activates natural killer (NK) cells through the transmembrane domain and the costimulatory signal transduction region, wherein said antigen binding domain is an ScFv which specifically binds to the FN3 domain of ROBO1; wherein said chimeric antigen receptor is a fusion protein with the structure of ScFV-CD8-4-1BB-CD3ζ, and the amino acid sequence of said ScFV-CD8-4-1BB-CD3ζ fusion protein is shown in SEQ ID NO: 3.
An ultrasonic diagnostic imaging system for producing spatially compounded images, comprising: an array transducer arranged to acquire component frames at a plurality of different look directions; a transmitter adapted to control the array transducer to steer scanlines in a trapezoidal scan format for each of a plurality of component frames, wherein the scanlines of each component frame are steered over a plurality of different scan angles with respect to a face of the array transducer; a compound image memory adapted to store component frames which have been acquired from different look directions; and a compound image processor adapted to combine the acquired component frames to form a spatially compounded image, wherein each scanline of each component frame is steered at a different scan angle with respect to a face of the array transducer relative to a respective scanline of each of the other component frames, and the scan angles of the scanlines of a component frame having a same angular increment relative to the scan angles of respective scanlines of another component frame, characterized in that the respective scanlines of each component frame emanate from the same points on the face of the array transducer. transducer arranged to acquire component frames at a plurality of different look directions; a transmitter adapted to control the array transducer to steer scanlines in a trapezoidal scan format for each of a plurality of component frames, wherein the scanlines of each component frame are steered over a plurality of different scan angles with respect to a face of the array transducer; a compound image memory adapted to store component frames which have been acquired from different look directions; and a compound image processor adapted to combine the acquired component frames to form a spatially compounded image, wherein each scanline of each component frame is steered at a different scan angle with respect to a face of the array transducer relative to a respective scanline of each of the other component frames, and the scan angles of the scanlines of a component frame having a same angular increment relative to the scan angles of respective scanlines of another component frame, characterized in that the respective scanlines of each component frame emanate from the same points on the face of the array transducer.
Method of motorised opening of a movable flap of a motor vehicle , the flap being of the type capable of being moved along a predefined trajectory, between a closed position and an open position, by motor-driven displacement means which can be actuated by at least one order , the flap comprising locking means designed to immobilise the flap in a closed position when they are activated, the flap further comprising obstacle detection means designed to detect obstacles likely to be located on the predefined trajectory and to allow the movement of the flap to be interrupted in the event of detection of at least one obstacle , the method comprising a detection step (ET1) following a task (AC) by a user on a order in order to open the flap , the detection step (ET1) consisting in implementing the obstacle detection means to detect an obstacle liable to be located on the trajectory, the method further comprising a deactivation step (ET2) consisting in deactivating the locking means in order to make possible the displacement of the flap , said method being characterised in that the detection step (ET1) and the deactivation step (ET2) are initiated simultaneously. the flap being of the type capable of being moved along a predefined trajectory, between a closed position and an open position, by motor-driven displacement means which can be actuated by at least one order , the flap comprising locking means designed to immobilise the flap in a closed position when they are activated, the flap further comprising obstacle detection means designed to detect obstacles likely to be located on the predefined trajectory and to allow the movement of the flap to be interrupted in the event of detection of at least one obstacle , the method comprising a detection step (ET1) following a task (AC) by a user on a order in order to open the flap , the detection step (ET1) consisting in implementing the obstacle detection means to detect an obstacle liable to be located on the trajectory, the method further comprising a deactivation step (ET2) consisting in deactivating the locking means in order to make possible the displacement of the flap , said method being characterised in that the detection step (ET1) and the deactivation step (ET2) are initiated simultaneously.
An electronic device comprising: a pixel array comprising a substrate (SB), a display layer, and an encapsulation layer (TFE) including a plurality of insulating layers; a touch array (TA) directly disposed on the encapsulation layer (TFE) and comprising a sensor detecting touch provided from the outside and a wiring electrically contacted to the sensor and comprising a first conductive pattern (CP1) and a second conductive pattern (CP2) disposed on the first conductive pattern (CP1); a protruding pattern (PP) disposed between the substrate (SB) and the first conductive pattern (CP1); and an interlayer insulating layer (ILD) disposed between the first conductive pattern (CP1) and the second conductive pattern (CP2) and in which an opening (IL-OP) overlapping at least a portion of the protruding pattern (PP) is defined, wherein the second conductive pattern (CP2) is electrically contacted to the first conductive pattern (CP1) through the opening (IL-OP). a pixel array comprising a substrate (SB), a display layer, and an encapsulation layer (TFE) including a plurality of insulating layers; a touch array (TA) directly disposed on the encapsulation layer (TFE) and comprising a sensor detecting touch provided from the outside and a wiring electrically contacted to the sensor and comprising a first conductive pattern (CP1) and a second conductive pattern (CP2) disposed on the first conductive pattern (CP1); a protruding pattern (PP) disposed between the substrate (SB) and the first conductive pattern (CP1); and an interlayer insulating layer (ILD) disposed between the first conductive pattern (CP1) and the second conductive pattern (CP2) and in which an opening (IL-OP) overlapping at least a portion of the protruding pattern (PP) is defined, wherein the second conductive pattern (CP2) is electrically contacted to the first conductive pattern (CP1) through the opening (IL-OP).
A phytopercolate derived from culturing micro-organisms identified by ATCC Deposit #PTA-5863, for use in the preventative treatment of one selected from: hypercholesterolaemia, high cholesterol levels; wherein the use comprises regulating cholesterol levels in an individual, and at the same time comprises regulating genes involved in lipoprotein metabolism.
A grease composition for constant velocity joints comprising: a lubricating base oil; a thickener comprising a nitrogen-containing compound; a triglyceride; a diester; and a boron nitride, wherein a total content of the triglyceride and the diester is 1 to 5 mass% based on a total amount of the grease composition, and a mass ratio of a content of the triglyceride to a content of the diester (triglyceride/diester) is 0.3 to 0.9, wherein the diester is an ester of a dicarboxylic acid and a monohydric alcohol. a lubricating base oil; a thickener comprising a nitrogen-containing compound; a triglyceride; a diester; and a boron nitride, wherein a total content of the triglyceride and the diester is 1 to 5 mass% based on a total amount of the grease composition, and a mass ratio of a content of the triglyceride to a content of the diester (triglyceride/diester) is 0.3 to 0.9,
A device for use in a cleaning installation for removing soot or similar inside deposits on the inside of a processing system such as a boiler, heat exchanger, flue gas filter, flow channel or the like, by intermittently blasting a gaseous medium into the processing system , characterised in that said device comprises a first valve and a second valve and two flow passages wherein, the device is adapted such that the first valve can be fluidly connected to the processing system via one of the flow passages and the second valve can be fluidly connected to the processing system via the other flow passage , simultaneously, and rotation means for rotatably mounting of the flow passages and wherein the flow passages each comprise a tubular member having a curved shape , characterised in that the curved shape is configured such that rotation of the flow passages allows for blasting in different directions.
A method for indicating physical obstacles while displaying a virtual reality environment , the method comprising: at an electronic device with one or more processors , memory , and one or more cameras : displaying a virtual reality environment ; determining a distance between the electronic device and a physical object ; determining whether the distance between the electronic device and the physical object is within a first threshold distance ; in accordance with a determination that the distance is within the first threshold distance , displaying a visual effect in the virtual reality environment ; determining whether the distance between the electronic device and the physical object is within a second threshold distance , wherein the second threshold distance is smaller than first threshold distance ; and in accordance with a determination that the distance is within the second threshold distance : replacing at least a first portion of the display of the virtual reality environment with a visual representation of at least part of a physical environment , the visual representation provided using the one or more cameras ; and continuing displaying a second portion of the display of the virtual reality environment , wherein the second portion of the display of the virtual reality environment is different from the first portion of the display of the virtual reality environment. displaying a virtual reality environment ; determining a distance between the electronic device and a physical object ; determining whether the distance between the electronic device and the physical object is within a first threshold distance ; in accordance with a determination that the distance is within the first threshold distance , displaying a visual effect in the virtual reality environment ; determining whether the distance between the electronic device and the physical object is within a second threshold distance , wherein the second threshold distance is smaller than first threshold distance ; and in accordance with a determination that the distance is within the second threshold distance : replacing at least a first portion of the display of the virtual reality environment with a visual representation of at least part of a physical environment , the visual representation provided using the one or more cameras ; and continuing displaying a second portion of the display of the virtual reality environment , wherein the second portion of the display of the virtual reality environment is different from the first portion of the display of the virtual reality environment. replacing at least a first portion of the display of the virtual reality environment with a visual representation of at least part of a physical environment , the visual representation provided using the one or more cameras ; and continuing displaying a second portion of the display of the virtual reality environment , wherein the second portion of the display of the virtual reality environment is different from the first portion of the display of the virtual reality environment.
Closure device for thermally separating building openings or spaces, in particular a fire door, comprising a two-part frame , the two-part frame having at least a first supporting structural element and a second supporting structural element , a thermal separation being formed between the structural elements in a connecting region formed for supporting connection of the structural elements , in such a way that heat transmission from a first outer face of the closure device to a second outer face of the closure device is reduced or prevented, each structural element being formed L-shaped or U-shaped in the connecting region , with at least two substantially mutually perpendicular limbs , and the first structural element forming at least one rebate facing of the frame and the second structural element forming at least one decorative facing of the frame , the connecting region having a fixing portion and an insulating portion adjacent thereto, and the fixing portion being formed multiple times smaller than the insulating portion , and the structural elements being interconnected via at least one plug-in connection , the plug-in connection forming the fixing portion , characterised in that each structural element has a first limb with at least two clearances and a second limb with at least two tabs , each tab of one structural element engaging in a clearance of the other structural element and the limbs enclosing a cavity, which is formed as an air gap for thermal separation or comprises a fire protection material . a thermal separation being formed between the structural elements in a connecting region formed for supporting connection of the structural elements , in such a way that heat transmission from a first outer face of the closure device to a second outer face of the closure device is reduced or prevented, each structural element being formed L-shaped or U-shaped in the connecting region , with at least two substantially mutually perpendicular limbs , and the first structural element forming at least one rebate facing of the frame and the second structural element forming at least one decorative facing of the frame , the connecting region having a fixing portion and an insulating portion adjacent thereto, and the fixing portion being formed multiple times smaller than the insulating portion , and the structural elements being interconnected via at least one plug-in connection , the plug-in connection forming the fixing portion , characterised in that each structural element has a first limb with at least two clearances and a second limb with at least two tabs , each tab of one structural element engaging in a clearance of the other structural element and the limbs enclosing a cavity, which is formed as an air gap for thermal separation or comprises a fire protection material .
Apparatus for use in holding artwork during transportation or storage, comprising: a substantially flat mounting panel provided with a plurality of retention members; and at least one clamp , configured to be moveable between an unengaged state, in which artwork can be removed from the apparatus, and an engaged state, in which the clamp secures the artwork to the apparatus; wherein the clamp comprises a base , configured to be secured to the mounting panel , and a gripping section ; and when artwork is secured to the apparatus, a first side of the artwork is supported on the mounting panel and the gripping section of the clamp presses on a second side of the artwork, opposite to the first side of the artwork; characterised in that the clamp comprises at least one rod that extends from the base of the clamp in a direction perpendicular to the surface of the mounting panel ; and the gripping section is configured to slide along the at least one rod to move between the unengaged state and the engaged state. a substantially flat mounting panel provided with a plurality of retention members; and at least one clamp , configured to be moveable between an unengaged state, in which artwork can be removed from the apparatus, and an engaged state, in which the clamp secures the artwork to the apparatus; wherein the clamp comprises a base , configured to be secured to the mounting panel , and a gripping section ; and when artwork is secured to the apparatus, a first side of the artwork is supported on the mounting panel and the gripping section of the clamp presses on a second side of the artwork, opposite to the first side of the artwork; characterised in that the clamp comprises at least one rod that extends from the base of the clamp in a direction perpendicular to the surface of the mounting panel ; and the gripping section is configured to slide along the at least one rod to move between the unengaged state and the engaged state.
Vaporiser-tank-unit comprising a vaporiser insert for an inhaler comprising - at least one electrical vaporiser for vaporising liquid fed to the vaporiser , and - electrical contacts for making electrical contact with the vaporiser insert for supplying with electrical energy and/or for receiving control signals for the vaporiser , wherein - the vaporiser insert has a base part with opposingly arranged faces and a jacket side between the faces arranged around at least one flow channel through which vapour can flow, wherein - at least one liquid opening for feeding vaporisable liquid from the outside into the vaporiser insert to the vaporiser is arranged on the jacket side of the base part , charaterised in that - the vaporiser-tank-unit comprises a liquid tank in which the vaporiser insert is inserted, wherein - the liquid tank has an insertion opening and an outlet opening , wherein - the vaporiser insert extends from the insertion opening to the outlet opening , wherein the in particular cartridge or jacket-shaped vaporiser insert can be arranged in an external part, in particular in a liquid tank , in particular inserted or slid thereinto. - at least one electrical vaporiser for vaporising liquid fed to the vaporiser , and - electrical contacts for making electrical contact with the vaporiser insert for supplying with electrical energy and/or for receiving control signals for the vaporiser , wherein - the vaporiser insert has a base part with opposingly arranged faces and a jacket side between the faces arranged around at least one flow channel through which vapour can flow, wherein - at least one liquid opening for feeding vaporisable liquid from the outside into the vaporiser insert to the vaporiser is arranged on the jacket side of the base part , charaterised in that - the vaporiser-tank-unit comprises a liquid tank in which the vaporiser insert is inserted, wherein - the liquid tank has an insertion opening and an outlet opening , wherein - the vaporiser insert extends from the insertion opening to the outlet opening , wherein the in particular cartridge or jacket-shaped vaporiser insert can be arranged in an external part, in particular in a liquid tank , in particular inserted or slid thereinto.