Coating having a thickness of from 1 μm to 100 μm, comprising a biodegradable polyesteramide (PEA) polymer which comprises at least two different functional groups pendant to the polymer backbone, whereby the two different functional groups comprise at least an unprotected hydrophilic functional group chosen from a carboxyl group and at least a protected hydrophobic functional group chosen from an ester group wherein the relative ratio of unprotected hydrophilic groups to protected hydrophobic functional groups varies from 0.17-3, wherein the polyesteramide is a copolymer according to structural Formula (III), wherein m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9; m+p+q=1 whereby m or p could be 0; n varies from 5 to 300 and wherein a is at least 0.1, b is at least 0.15 and a+b=1; wherein the m unit, p unit, a unit, and b unit are each randomly distributed throughout the PEA; whereby: - R 1 is independently selected from the group consisting of (C 2 -C 20 ) alkyl; - R 3 and R 4 in a single backbone unit m or p, respectively, are independently selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 6 -C 10 )aryl, -(CH 2 )SH, -(CH 2 ) 2 S(CH) 3 ,(CH 3 ) 2 -CH-CH 2 -,-CH(CH 3 ) 2 , -CH(CH 3 )-CH 2 -CH 3 , -CH 2 -C 6 H 5 , -(CH 2 ) 4 -NH 2 , and mixtures thereof; - R 5 is independently selected from the group consisting of (C 2 -C 20 )alkyl, (C 2 -C 20 )alkylene; - R 6 is selected from bicyclic-fragments of 1,4:3,6-dianhydrohexitols of structural formula (II); - R 7 is independently selected from the group consisting of (C 6 -C 10 ) aryl (C 1 -C 6 ) alkyl or a protecting group; and - R 8 is -(CH 2 ) 4 -. wherein m+p varies from 0.9-0.1 and q varies from 0.1 to 0.9; m+p+q=1 whereby m or p could be 0; n varies from 5 to 300 and wherein a is at least 0.1, b is at least 0.15 and a+b=1; wherein the m unit, p unit, a unit, and b unit are each randomly distributed throughout the PEA; whereby: - R 1 is independently selected from the group consisting of (C 2 -C 20 ) alkyl; - R 3 and R 4 in a single backbone unit m or p, respectively, are independently selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 6 -C 10 )aryl, -(CH 2 )SH, -(CH 2 ) 2 S(CH) 3 ,(CH 3 ) 2 -CH-CH 2 -,-CH(CH 3 ) 2 , -CH(CH 3 )-CH 2 -CH 3 , -CH 2 -C 6 H 5 , -(CH 2 ) 4 -NH 2 , and mixtures thereof; - R 5 is independently selected from the group consisting of (C 2 -C 20 )alkyl, (C 2 -C 20 )alkylene; - R 6 is selected from bicyclic-fragments of 1,4:3,6-dianhydrohexitols of structural formula (II); - R 7 is independently selected from the group consisting of (C 6 -C 10 ) aryl (C 1 -C 6 ) alkyl or a protecting group; and - R 8 is -(CH 2 ) 4 -. - R 1 is independently selected from the group consisting of (C 2 -C 20 ) alkyl; - R 3 and R 4 in a single backbone unit m or p, respectively, are independently selected from the group consisting of hydrogen, (C 1 -C 6 )alkyl, (C 2 -C 6 )alkenyl, (C 2 -C 6 )alkynyl, (C 6 -C 10 )aryl, -(CH 2 )SH, -(CH 2 ) 2 S(CH) 3 ,(CH 3 ) 2 -CH-CH 2 -,-CH(CH 3 ) 2 , -CH(CH 3 )-CH 2 -CH 3 , -CH 2 -C 6 H 5 , -(CH 2 ) 4 -NH 2 , and mixtures thereof; - R 5 is independently selected from the group consisting of (C 2 -C 20 )alkyl, (C 2 -C 20 )alkylene; - R 6 is selected from bicyclic-fragments of 1,4:3,6-dianhydrohexitols of structural formula (II); - R 7 is independently selected from the group consisting of (C 6 -C 10 ) aryl (C 1 -C 6 ) alkyl or a protecting group; and - R 8 is -(CH 2 ) 4 -. <EOS>