A nasogastric tube securement system , the system comprising: a base layer configured to be adhered to a nose, the base layer having a first major surface comprising a skin-contact adhesive and a second major surface opposite the first major surface , the base layer having a footprint area of A; and a coupling layer comprising a first end comprising coupling means configured to be repositionably coupled to the second major surface of the base layer , the first end having a footprint area of at least 0.3A, wherein a width of the first end of the coupling layer has a shape suitable for covering a bridge of the nose and at least a part of the lateral sides of the nose, a second end configured to secure a nasogastric tube (T), and a linear middle section connecting the first end and the second end , the middle section elongated along a longitudinal direction (D), and; wherein the first end and the second end are each wider than the middle section in the lateral direction (L) that is oriented substantially perpendicularly with respect to the longitudinal direction (D), wherein at least the middle section and the second end of the coupling layer generally form an "L" shape, and wherein the coupling layer is asymmetrical about the longitudinal direction (D). a base layer configured to be adhered to a nose, the base layer having a first major surface comprising a skin-contact adhesive and a second major surface opposite the first major surface , the base layer having a footprint area of A; and a coupling layer comprising a first end comprising coupling means configured to be repositionably coupled to the second major surface of the base layer , the first end having a footprint area of at least 0.3A, wherein a width of the first end of the coupling layer has a shape suitable for covering a bridge of the nose and at least a part of the lateral sides of the nose, a second end configured to secure a nasogastric tube (T), and a linear middle section connecting the first end and the second end , the middle section elongated along a longitudinal direction (D), and; wherein the first end and the second end are each wider than the middle section in the lateral direction (L) that is oriented substantially perpendicularly with respect to the longitudinal direction (D), wherein at least the middle section and the second end of the coupling layer generally form an "L" shape, and wherein the coupling layer is asymmetrical about the longitudinal direction (D). a first end comprising coupling means configured to be repositionably coupled to the second major surface of the base layer , the first end having a footprint area of at least 0.3A, wherein a width of the first end of the coupling layer has a shape suitable for covering a bridge of the nose and at least a part of the lateral sides of the nose, a second end configured to secure a nasogastric tube (T), and a linear middle section connecting the first end and the second end , the middle section elongated along a longitudinal direction (D), and; wherein the first end and the second end are each wider than the middle section in the lateral direction (L) that is oriented substantially perpendicularly with respect to the longitudinal direction (D), wherein at least the middle section and the second end of the coupling layer generally form an "L" shape, and wherein the coupling layer is asymmetrical about the longitudinal direction (D). <EOS>