A targeting system for providing visualization of a trajectory for a medical instrument, the targeting system comprising: a fixture comprising a first attachment feature that secures the fixture at a predetermined location relative to a patient; a first laser , wherein the first laser projects first light along a first plane; and a second laser , wherein the second laser projects second light along a second plane nonparallel to the first plane such that, at an intersection of the first plane with the second plane, the first light and the second light cooperate to produce a first targeting line that indicates the trajectory; wherein the first light comprises a first wavelength corresponding to a first color within the visible portion of the electromagnetic spectrum; wherein the second light comprises a second wavelength corresponding to a second color within the visible portion of the electromagnetic spectrum; wherein the second wavelength is different from the first wavelength and the second color is different from the first color; characterized in that the first laser and second laser are both attached to the fixture; wherein the first laser is adjustably attached to the fixture such that adjustment of at least one of a first roll setting, a first pitch setting, and a first yaw setting of the first laser is adjustable to adjust a first orientation of the first plane, relative to the fixture ; wherein the second laser is adjustably attached to the fixture such that adjustment of at least one of a second roll setting, a second pitch setting, and a second yaw setting of the second laser is adjustable to adjust a second orientation of the second plane, relative to the fixture . a fixture comprising a first attachment feature that secures the fixture at a predetermined location relative to a patient; a first laser , wherein the first laser projects first light along a first plane; and a second laser , wherein the second laser projects second light along a second plane nonparallel to the first plane such that, at an intersection of the first plane with the second plane, the first light and the second light cooperate to produce a first targeting line that indicates the trajectory; wherein the first light comprises a first wavelength corresponding to a first color within the visible portion of the electromagnetic spectrum; wherein the second light comprises a second wavelength corresponding to a second color within the visible portion of the electromagnetic spectrum; wherein the second wavelength is different from the first wavelength and the second color is different from the first color; characterized in that the first laser and second laser are both attached to the fixture; wherein the first laser is adjustably attached to the fixture such that adjustment of at least one of a first roll setting, a first pitch setting, and a first yaw setting of the first laser is adjustable to adjust a first orientation of the first plane, relative to the fixture ; wherein the second laser is adjustably attached to the fixture such that adjustment of at least one of a second roll setting, a second pitch setting, and a second yaw setting of the second laser is adjustable to adjust a second orientation of the second plane, relative to the fixture . <EOS>