mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: A-B is a 6-5 membered fused indolizine ring system, which is selected from: L is S; each R 1 is -CN; each R 2 is independently selected from hydrogen, halogen, CN, C 1-10 alkyl, and C 3-10 cycloalkyl, ;each R 3 is hydrogen; each R 4 and R 5 are independently selected from C 1-10 alkyl; or R 4 and R 5 together with the carbon atom to which they are attached form a ring of 3 to 7 members containing 0, 1, or 2 heteroatoms independently selected from oxygen, sulfur and nitrogen; M is hydrogen, C 1-4 alkyl or a pharmaceutically acceptable cation; m is independently selected from 0, 1, 2 and 3; n is independently selected from 0, 1, 2, and 3; o is selected from 1, 2, and 3; p is independently selected from 0, 1, 2 and 3. A-B is a 6-5 membered fused indolizine ring system, which is selected from: L is S; each R 1 is -CN; each R 2 is independently selected from hydrogen, halogen, CN, C 1-10 alkyl, and C 3-10 cycloalkyl, ;each R 3 is hydrogen; each R 4 and R 5 are independently selected from C 1-10 alkyl; or R 4 and R 5 together with the carbon atom to which they are attached form a ring of 3 to 7 members containing 0, 1, or 2 heteroatoms independently selected from oxygen, sulfur and nitrogen; M is hydrogen, C 1-4 alkyl or a pharmaceutically acceptable cation; m is independently selected from 0, 1, 2 and 3; n is independently selected from 0, 1, 2, and 3; o is selected from 1, 2, and 3; p is independently selected from 0, 1, 2 and 3.
A sole structure comprising: a plate , an upper midsole component , and a lower midsole component ; the upper midsole component having an upper surface and a lower surface , and the upper midsole component having an opening ; the lower midsole component having a base portion including an upper surface and a lower surface , the upper surface of the base portion of the lower midsole component being bonded to the lower surface of the upper midsole component ; the lower midsole component having a raised portion , the raised portion having an upper surface , the raised portion extending through the opening; the upper surface of the raised portion being in the same plane as the upper surface of the upper midsole component; the plate contacting the upper surface of the upper midsole component ; and wherein the plate is secured to the upper surface of the raised portion , and unsecured to the upper midsole component . a plate , an upper midsole component , and a lower midsole component ; the upper midsole component having an upper surface and a lower surface , and the upper midsole component having an opening ; the lower midsole component having a base portion including an upper surface and a lower surface , the upper surface of the base portion of the lower midsole component being bonded to the lower surface of the upper midsole component ; the lower midsole component having a raised portion , the raised portion having an upper surface , the raised portion extending through the opening; the upper surface of the raised portion being in the same plane as the upper surface of the upper midsole component; the plate contacting the upper surface of the upper midsole component ; and wherein the plate is secured to the upper surface of the raised portion , and unsecured to the upper midsole component .
A method of purifying a protein-nanoparticle conjugate, the method comprising: contacting a mixture of the protein-nanoparticle conjugate, free protein, and a buffer to a multimodal medium to separate the protein-nanoparticle conjugate from free protein, wherein the multimodal medium has a size exclusion mode and a capture mode, and wherein the multimodal medium comprises a polysaccharide that has hydroxyapatite microcrystals entrapped therein, wherein the protein-nanoparticle conjugate is excluded from entering pores of the multimodal medium and the free protein is captured in the multimodal medium; and collecting the protein-nanoparticle conjugate in the flow-through, thereby purifying the protein-nanoparticle conjugate. contacting a mixture of the protein-nanoparticle conjugate, free protein, and a buffer to a multimodal medium to separate the protein-nanoparticle conjugate from free protein, wherein the multimodal medium has a size exclusion mode and a capture mode, and wherein the multimodal medium comprises a polysaccharide that has hydroxyapatite microcrystals entrapped therein, wherein the protein-nanoparticle conjugate is excluded from entering pores of the multimodal medium and the free protein is captured in the multimodal medium; and collecting the protein-nanoparticle conjugate in the flow-through, thereby purifying the protein-nanoparticle conjugate.
A user equipment , comprising processing circuitry arranged to communicate with an evolved Node B, eNodeB, using a 3GPP Long Term Evolution, LTE, or Long Term Evolution-Advanced, LTE-A, network connection and to facilitate device-to-device communications with a receiving user equipment using a direct network connection, by performing operations to: send a request message for obtaining a transmission time for a data transmission, to the receiving user equipment , during a resource contention window , the resource contention window allocated for scheduling device-to-device communications in a wireless channel using a contention channel access technique, the request message indicating a size for the data transmission; receive a response to the request message, from the receiving user equipment , the response confirming the request message and designating the transmission time for the data transmission, and the designated transmission time occurring within a scheduled transmission window allocated for conducting the device-to-device communications; and perform the data transmission with the receiving user equipment, during the scheduled transmission window allocated for conducting the device-to-device communications, on the wireless channel at the designated transmission time. send a request message for obtaining a transmission time for a data transmission, to the receiving user equipment , during a resource contention window , the resource contention window allocated for scheduling device-to-device communications in a wireless channel using a contention channel access technique, the request message indicating a size for the data transmission; receive a response to the request message, from the receiving user equipment , the response confirming the request message and designating the transmission time for the data transmission, and the designated transmission time occurring within a scheduled transmission window allocated for conducting the device-to-device communications; and perform the data transmission with the receiving user equipment, during the scheduled transmission window allocated for conducting the device-to-device communications, on the wireless channel at the designated transmission time.
A block copolymer comprising: one or more blocks of an acrylate polymer; and one or more blocks of a chloroprene polymer, wherein a number average molecular weight of the block copolymer is 110,000 or more, a number average molecular weight of the block of a chloroprene polymer is 80,000 or more in total, and the block copolymer has a functional group with a structure represented by the following chemical formula or : wherein in the chemical formula , R 1 represents hydrogen, chlorine, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aryl group or a substituted, or unsubstituted heterocyclyl group; characterised in that the acrylate is alkyl acrylate having an alkyl group having 5 or more carbon atoms and that the block copolymer is obtained by performing radical polymerization in the presence of a RAFT agent. one or more blocks of an acrylate polymer; and one or more blocks of a chloroprene polymer, wherein a number average molecular weight of the block copolymer is 110,000 or more, a number average molecular weight of the block of a chloroprene polymer is 80,000 or more in total, and the block copolymer has a functional group with a structure represented by the following chemical formula or : wherein in the chemical formula , R 1 represents hydrogen, chlorine, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aryl group or a substituted, or unsubstituted heterocyclyl group; characterised in that the acrylate is alkyl acrylate having an alkyl group having 5 or more carbon atoms and that the block copolymer is obtained by performing radical polymerization in the presence of a RAFT agent.
An external table height adjustment mechanism for a printer table , the external table height adjustment mechanism comprising: a table interface including a mounting bracket adapted to attach to a portion of the printer table and a thermal expansion compensation pin running through two ends of the mounting bracket ; a frame mounting block adapted to attach to a supporting frame of the printer table ; a linkage structure ; and a rod extending away from the frame mounting block ; a rod interface adapted to attach to said rod; wherein the linkage structure is attached, using a mechanical attachment that enables pivoting at the point of attachment, to the rod interface and the compensation pin at a first end of the linkage structure such that a movement of said rod toward and away from said frame mounting block causes the linkage structure to pivot; and wherein the linkage structure is further attached, using a mechanical attachment that enables pivoting at the point of attachment, to the frame mounting block at an opposite end of the first end. a table interface including a mounting bracket adapted to attach to a portion of the printer table and a thermal expansion compensation pin running through two ends of the mounting bracket ; a frame mounting block adapted to attach to a supporting frame of the printer table ; a linkage structure ; and a rod extending away from the frame mounting block ; a rod interface adapted to attach to said rod; wherein the linkage structure is attached, using a mechanical attachment that enables pivoting at the point of attachment, to the rod interface and the compensation pin at a first end of the linkage structure such that a movement of said rod toward and away from said frame mounting block causes the linkage structure to pivot; and wherein the linkage structure is further attached, using a mechanical attachment that enables pivoting at the point of attachment, to the frame mounting block at an opposite end of the first end.
A wound dressing apparatus for reduced pressure wound therapy, comprising: a pump assembly (72; 254; 314); a power source (76; 256; 316); and a dressing member (78; 252; 312) wherein the pump assembly and the power source are supported by the dressing member; wherein the dressing member comprises one or more absorbent or other layers wherein the pump assembly is embedded within, supported on top of or adjacent to said one or more layers; a cover layer or backing layer; and characterized in that the wound dressing apparatus further comprises a hinge positioned between the power source and the pump assembly to improve flexibility. a pump assembly (72; 254; 314); a power source (76; 256; 316); and a dressing member (78; 252; 312) wherein the pump assembly and the power source are supported by the dressing member; wherein the dressing member comprises one or more absorbent or other layers wherein the pump assembly is embedded within, supported on top of or adjacent to said one or more layers; a cover layer or backing layer; and characterized in that the wound dressing apparatus further comprises a hinge positioned between the power source and the pump assembly to improve flexibility. one or more absorbent or other layers wherein the pump assembly is embedded within, supported on top of or adjacent to said one or more layers; a cover layer or backing layer; and characterized in that the wound dressing apparatus further comprises a hinge positioned between the power source and the pump assembly to improve flexibility.
A method for producing a press-formed product including two ridges , a top plate section located between the two ridges , and two vertical wall sections extending from the top plate section via the ridges , the two ridges each having a concave ridge convexly curved toward an inner side of the corresponding vertical wall section and a convex ridge convexly curved toward an outer side of the corresponding vertical wall section , a linear distance between a center of each of the concave ridges and a center of the corresponding convex ridge being 15 times a spacing between the two ridges or less, the top plate section having a concave area located between the concave ridges and a convex area located between the convex ridges , the vertical wall sections having concave-correspondence vertical wall areas adjacent to the concave ridges and convex-correspondence vertical wall areas adjacent to the convex ridges, the production method comprising: a placement step of placing a blank metal plate in such a way that the blank metal plate extends off opposite sides of a vertex of a first punch ; a first pressing step of causing the blank plate to undergo bend forming by using the first punch , a pad , and a first die in such a way that the concave ridges , the concave area , and areas of the concave-correspondence vertical wall areas that are areas adjacent to the concave ridges are formed in the blank plate to produce an intermediate formed product ; and a second pressing step of causing the intermediate formed product to undergo draw forming by using a second punch , a second die , and a blank holder in such a way that the convex ridges , the convex area , areas of the convex-correspondence vertical wall areas that are areas adjacent to the convex ridges are formed in the intermediate formed product . a placement step of placing a blank metal plate in such a way that the blank metal plate extends off opposite sides of a vertex of a first punch ; a first pressing step of causing the blank plate to undergo bend forming by using the first punch , a pad , and a first die in such a way that the concave ridges , the concave area , and areas of the concave-correspondence vertical wall areas that are areas adjacent to the concave ridges are formed in the blank plate to produce an intermediate formed product ; and a second pressing step of causing the intermediate formed product to undergo draw forming by using a second punch , a second die , and a blank holder in such a way that the convex ridges , the convex area , areas of the convex-correspondence vertical wall areas that are areas adjacent to the convex ridges are formed in the intermediate formed product .
A computer hardware system comprising at least one processing unit coupled to a memory , wherein the memory is encoded with computer executable instructions that when executed cause the at least one processing unit to: receive a client message at a published endpoint , the message formatted according to a description of a first application programming interface ; parse an instruction from the message according to the description; pass the instruction to a package via a function of the first application programming interface , the package having a second application programming interface and a logic ; receive, over the second application programming interface, a result based on the instruction and the logic; and respond to the client message based on the result, wherein the description has a generic format. receive a client message at a published endpoint , the message formatted according to a description of a first application programming interface ; parse an instruction from the message according to the description; pass the instruction to a package via a function of the first application programming interface , the package having a second application programming interface and a logic ; receive, over the second application programming interface, a result based on the instruction and the logic; and respond to the client message based on the result,
Hydropneumatic piston cylinder arrangement, in particular for use as a spring element and/or shock absorber element, having a cylinder which can be subjected to different loads, the cylinder chamber of which accommodates a hydraulic fluid, and having a pneumatic spring-loaded accumulator which supports the cylinder against the loads and is operatively connected to the hydraulic fluid in the cylinder chamber , wherein the pneumatic spring-loaded accumulator consists of at least two accumulator devices combined to form one structural unit which, independently of each other and due to different precharge pressures, have their own independent spring characteristics, wherein the respective spring characteristics, taken together, produce an overall spring characteristic, wherein both accumulator devices are formed by piston accumulators , wherein a first piston accumulator with its cylindrical further accumulator housing is movable in the cylinder chamber , accommodating the hydraulic fluid, of the cylinder , along the axis of said cylinder and is guided at least at the open end thereof, wherein, at least in one operating state, a separating piston of a second piston accumulator separates two fluid chambers from each other in the one accumulator housing , wherein the one accumulator housing separates two further fluid chambers from each other in a further accumulator housing of the second piston accumulator , and wherein the further accumulator housing again defines a further fluid chamber in the cylinder , characterised in that all fluid chambers which are arranged towards a closure body of the cylinder merge into each other to form a common overall fluid chamber.
A manufacturing method of a ring-shaped band saw blade , the manufacturing method being characterized by comprising: a ring forming step of welding opposite ends of a band saw blade including a body part having a band shape, and a tooth part including a plurality of teeth formed on one side part of the body part , to form a ring shape; a polishing step of polishing an inner surface , an outer surface , and an end face on a side opposite to the tooth part in the ring-shaped band saw blade ; and a tip tooth tip forming step of positioning, after the polishing step, the ring-shaped band saw blade by use of one of the inner surface and the outer surface , and the end face as references, joining a cutting tip to tooth tips of the plurality of teeth by welding, and polishing the joined cutting tip to form a tooth tip shape. a polishing step of polishing an inner surface , an outer surface , and an end face on a side opposite to the tooth part in the ring-shaped band saw blade ; and a tip tooth tip forming step of positioning, after the polishing step, the ring-shaped band saw blade by use of one of the inner surface and the outer surface , and the end face as references, joining a cutting tip to tooth tips of the plurality of teeth by welding, and polishing the joined cutting tip to form a tooth tip shape.
A method for manufacturing a medical instrument , comprising the steps of: fabricating an ultrasonic horn or concentrator having a shape and size configured for a selected type of surgical procedure; operatively connecting an upstream or input portion of said horn or concentrator to an ultrasonic transducer assembly ; operating at least one laser vibrometer to automatically track movement of an operative tip of said horn or concentrator ; automatically recording at least one signal encoding the tracked movement; processing the recorded signal to generate a time reversal waveform; and storing said time reversal waveform comprising transducer instructions in a storage medium , energizing said transducer assembly to generate at an input or upstream end of said horn or concentrator an ultrasonic calibration vibration having a desired motion pattern and desired frequency and amplitude characteristics, wherein the tracking of the movement of said operative tip by the operating of said at least one laser vibrometer is performed upon generation of said calibration vibration at said input or upstream end of said horn or concentrator . fabricating an ultrasonic horn or concentrator having a shape and size configured for a selected type of surgical procedure; operatively connecting an upstream or input portion of said horn or concentrator to an ultrasonic transducer assembly ; operating at least one laser vibrometer to automatically track movement of an operative tip of said horn or concentrator ; automatically recording at least one signal encoding the tracked movement; processing the recorded signal to generate a time reversal waveform; and storing said time reversal waveform comprising transducer instructions in a storage medium , energizing said transducer assembly to generate at an input or upstream end of said horn or concentrator an ultrasonic calibration vibration having a desired motion pattern and desired frequency and amplitude characteristics, wherein the tracking of the movement of said operative tip by the operating of said at least one laser vibrometer is performed upon generation of said calibration vibration at said input or upstream end of said horn or concentrator .
A method for Device to Device, D2D, communication, comprising: generating , by a first D2D device, a data packet, the data packet being a data packet of a Semi-Persistent-Scheduling, SPS, service or a Semi-Persistent-Transmission, SPT, service, the data packet comprising first Scheduling Assignment, SA, information, and the first SA information comprising information of a period of the SPS service or the SPT service; and transmitting , by the first D2D device, the data packet to a second D2D device, wherein the first D2D device and the second D2D device are D2D devices working in mode 2. generating , by a first D2D device, a data packet, the data packet being a data packet of a Semi-Persistent-Scheduling, SPS, service or a Semi-Persistent-Transmission, SPT, service, the data packet comprising first Scheduling Assignment, SA, information, and the first SA information comprising information of a period of the SPS service or the SPT service; and transmitting , by the first D2D device, the data packet to a second D2D device, wherein the first D2D device and the second D2D device are D2D devices working in mode 2.
Method of reprocessing nitride spent nuclear fuel in salt melts, involving its chlorination in the melt of a mixture of chlorides of alkali and/or alkaline-earth metals containing cadmium dichloride, wherein the chlorination is carried out in an apparatus for reprocessing nitride spent nuclear fuel with the use of an inert gas atmosphere, characterized in that the chlorination is carried out in an apparatus having a heated zone (I) in which a reactor with a LiCl-KCl melt and a nitride spent nuclear fuel immersed therein is located, as well as a cold zone (II) located below the reactor , wherein the LiCl-KCl melt has been prepared by a zone melting method in order to remove oxygen impurities and mixed with purified CdCl 2 , wherein in the course of the chlorination, the heated zone (I) of the apparatus with reactor is heated up to a temperature higher than 700°C, the nitride spent nuclear fuel is held being immersed into the LiCl-KCl-CdCl 2 melt to the point of complete chlorination, while the cold zone (II) of the apparatus is used for crystallizing the metallic cadmium formed during the chlorination