mhurhangee/patent-ind-claim-en huggingface dataset:
An isolated binding polypeptide consisting of a variable heavy (VH) domain that specifically binds to PDGFRβ, wherein the VH domain comprises CDR3, CDR2, and CDR1 amino acid sequences, wherein (i) the CDR3 comprises the amino acid sequence set forth in SEQ ID NO: 1, the CDR2 comprises an amino acid sequence set forth in SEQ ID NO: 3, and the CDR1 comprises the amino acid sequence set forth in SEQ ID NO: 35 and wherein the VH domain comprises an amino acid sequence selected from the group consisting of SEQ ID NOs: 321-324, or (ii) the CDR3 comprises the amino acid sequence set forth in SEQ ID NO: 1, the CDR2 comprises an amino acid sequence set forth in SEQ ID NO: 25, and the CDR1 comprises the amino acid sequence set forth in SEQ ID NO: 46 and wherein the VH domain comprises an amino acid sequence selected from the group consisting of SEQ ID NOs: 345 and 360, and wherein the isolated binding polypeptide binds the PDGFRβ with a Kd of less than 250pM as measured by surface plasmon resonance, preferably with a Kd of less than 100pM as measured by surface plasmon resonance. (i) the CDR3 comprises the amino acid sequence set forth in SEQ ID NO: 1, the CDR2 comprises an amino acid sequence set forth in SEQ ID NO: 3, and the CDR1 comprises the amino acid sequence set forth in SEQ ID NO: 35 and wherein the VH domain comprises an amino acid sequence selected from the group consisting of SEQ ID NOs: 321-324, or (ii) the CDR3 comprises the amino acid sequence set forth in SEQ ID NO: 1, the CDR2 comprises an amino acid sequence set forth in SEQ ID NO: 25, and the CDR1 comprises the amino acid sequence set forth in SEQ ID NO: 46 and wherein the VH domain comprises an amino acid sequence selected from the group consisting of SEQ ID NOs: 345 and 360,
A baler comprising: a frame ; a compression system coupled to the frame , the compression system at least partially defining a compression chamber ; a feed pan at least partially defining a pre-compression chamber in operable communication with the compression chamber , wherein the feed pan includes an inlet defining an inlet area and an outlet defining an outlet area , and wherein the outlet of the pre-compression chamber is open to the compression chamber of the compression system ; at least one actuator coupled to the feed pan ; and the at least one actuator includes a first set of one or more actuators in operable communication with the feed pan and configured to adjust the outlet area ; and the baler further comprising a second set of one or more actuators in operable communication with the feed pan and configured to adjust the inlet area ; and a controller in operable communication with the at least one actuator , and wherein the controller is configured to adjust the inlet area and the outlet area independently characterized in that the baler comprising a sensor configured to output signals to the controller representative of at least of the inlet area and the outlet area . a frame ; a compression system coupled to the frame , the compression system at least partially defining a compression chamber ; a feed pan at least partially defining a pre-compression chamber in operable communication with the compression chamber , wherein the feed pan includes an inlet defining an inlet area and an outlet defining an outlet area , and wherein the outlet of the pre-compression chamber is open to the compression chamber of the compression system ; at least one actuator coupled to the feed pan ; and the at least one actuator includes a first set of one or more actuators in operable communication with the feed pan and configured to adjust the outlet area ; and the baler further comprising a second set of one or more actuators in operable communication with the feed pan and configured to adjust the inlet area ; and a controller in operable communication with the at least one actuator , and wherein the controller is configured to adjust the inlet area and the outlet area independently characterized in that the baler comprising a sensor configured to output signals to the controller representative of at least of the inlet area and the outlet area .
Radiofrequency volume coil , suitable for use in a nuclear magnetic resonance apparatus (NMR) for the transmission of NMR signals, comprising a plurality of longitudinal conductors positioned along a longitudinal axis and a detuning circuit to modify the resonance frequency of the natural mode of said coil and able to detune said coil without contact with said longitudinal conductors , said detuning circuit being comprised of a plurality of resonant circuits having a switching device , said plurality of resonant circuits resonating: - at a first resonance frequency close to the resonance frequency of the natural mode of said coil when the means of switching is in the closed position in such a way as to induce by the inductive effect a reactance on each longitudinal conductor and to modify the resonance frequency of the natural mode of said coil ; - at a second resonance frequency higher than or less than the resonance frequency of the natural mode of said coil when the means of switching is in the open position so as to minimise the coupling between the detuning circuit and the longitudinal conductors , said volume coil being characterised in that the coil is a 1/4 wave coil and in that the resonant circuits are positioned longitudinally in the coil along the longitudinal axis at a position where the magnetic field B1 is maximal. - at a first resonance frequency close to the resonance frequency of the natural mode of said coil when the means of switching is in the closed position in such a way as to induce by the inductive effect a reactance on each longitudinal conductor and to modify the resonance frequency of the natural mode of said coil ; - at a second resonance frequency higher than or less than the resonance frequency of the natural mode of said coil when the means of switching is in the open position so as to minimise the coupling between the detuning circuit and the longitudinal conductors ,
An exercise bar assembly comprising: a pair of rotating grip assemblies , each including a generally planar frame and a hand grip mounted within the frame for rotation in the plane of the frame; a center bar assembly defining a longitudinal axis (L) and opposite ends along the longitudinal axis, each of the opposite ends fixed to said frame of a corresponding one of the rotating grip assemblies along the longitudinal axis (L); and an elongated elastic element having opposite ends , each of said opposite ends having a mounting collar engageable to a bearing post (28a-f) on a corresponding one of said pair of rotating grip assemblies and extending along said longitudinal axis (L) between said pair of rotating grip assemblies , said elastic element resisting rotation of said hand grip in each of the rotating grip assemblies , characterized in that each of said rotating grip assemblies includes at least one fixed bearing post , separate from said bearing post (28a-f), projecting perpendicularly from said frame and arranged on said frame to contact said elastic element upon rotation of said hand grip . a pair of rotating grip assemblies , each including a generally planar frame and a hand grip mounted within the frame for rotation in the plane of the frame; a center bar assembly defining a longitudinal axis (L) and opposite ends along the longitudinal axis, each of the opposite ends fixed to said frame of a corresponding one of the rotating grip assemblies along the longitudinal axis (L); and an elongated elastic element having opposite ends , each of said opposite ends having a mounting collar engageable to a bearing post (28a-f) on a corresponding one of said pair of rotating grip assemblies and extending along said longitudinal axis (L) between said pair of rotating grip assemblies , said elastic element resisting rotation of said hand grip in each of the rotating grip assemblies , characterized in that each of said rotating grip assemblies includes at least one fixed bearing post , separate from said bearing post (28a-f), projecting perpendicularly from said frame and arranged on said frame to contact said elastic element upon rotation of said hand grip .
Evaporation apparatus comprising: (i) At least one inlet for a liquid to be evaporated, the inlet(s) being located at the top of the evaporation apparatus (2.1) and/or on a side of the evaporation apparatus (2.2); (ii) Optionally, a seal pot into which any inlet located at the top of the evaporation apparatus (2.1) immerses; (iii) A liquid distributor , which is located • underneath any inlet located at the top of the evaporation apparatus (2.1) or, if present, underneath the seal pot , and / or • above any inlet located on a side of the evaporation apparatus (2.2), the liquid distributor being connected to the inlet located on a side of the evaporation apparatus (2.2); (iv) An upper heating unit (5.1) arranged horizontally in the evaporation apparatus underneath the liquid distributor ; (v) A lower heating unit (5.2) arranged horizontally or with a downward slope in the evaporation apparatus underneath the upper heating unit (5.1); (vi) A heatable flat plate arranged horizontally in the bottom of the evaporation apparatus underneath the lower heating unit (5.2); (vii) An outlet for the evaporated liquid (i.e. the desired gas stream) . (i) At least one inlet for a liquid to be evaporated, the inlet(s) being located at the top of the evaporation apparatus (2.1) and/or on a side of the evaporation apparatus (2.2); (ii) Optionally, a seal pot into which any inlet located at the top of the evaporation apparatus (2.1) immerses; (iii) A liquid distributor , which is located • underneath any inlet located at the top of the evaporation apparatus (2.1) or, if present, underneath the seal pot , and / or • above any inlet located on a side of the evaporation apparatus (2.2), the liquid distributor being connected to the inlet located on a side of the evaporation apparatus (2.2); • underneath any inlet located at the top of the evaporation apparatus (2.1) or, if present, underneath the seal pot , and / or • above any inlet located on a side of the evaporation apparatus (2.2), the liquid distributor being connected to the inlet located on a side of the evaporation apparatus (2.2); (iv) An upper heating unit (5.1) arranged horizontally in the evaporation apparatus underneath the liquid distributor ; (v) A lower heating unit (5.2) arranged horizontally or with a downward slope in the evaporation apparatus underneath the upper heating unit (5.1); (vi) A heatable flat plate arranged horizontally in the bottom of the evaporation apparatus underneath the lower heating unit (5.2); (vii) An outlet for the evaporated liquid (i.e. the desired gas stream) .
Double water-oil-water emulsion, comprising: - an internal aqueous phase E1, comprising glucose from 31 to 70% w/w, preferably from 35 to 55% w/w by weight relative to the mass of E1; - an oily phase H, comprising an animal and/or vegetable fat, and a lipophilic emulsifier; the mass ratio of the internal aqueous phase E1 on the oily phase H being from 7:3 to 5:5; and - an external aqueous phase E2, comprising a water-soluble emulsifier. - an internal aqueous phase E1, comprising glucose from 31 to 70% w/w, preferably from 35 to 55% w/w by weight relative to the mass of E1; - an oily phase H, comprising an animal and/or vegetable fat, and a lipophilic emulsifier; the mass ratio of the internal aqueous phase E1 on the oily phase H being from 7:3 to 5:5; and - an external aqueous phase E2, comprising a water-soluble emulsifier.
A firing mechanism , comprising: a hammer pivotably mounted about a hammer axis ; a sear pivotably mounted about a sear axis , wherein the sear comprises a first hook operable to provide a primary interface with the hammer ; an actuator comprising an actuator base and an actuator arm extending radially outwardly from the actuator base , wherein the actuator base is pivotably mounted about an actuator axis ; and wherein the sear further comprises a second hook operable to provide a secondary interface with the hammer and wherein, upon failure of the first hook , the second hook secures the hammer and prevents discharge of the firearm characterized in that the actuator arm comprises a notch and further comprising a trigger operable to rotate the actuator about the actuator axis to disengage the second hook of the sear from the notch of the actuator arm , thereby permitting the first hook of the sear to release the hammer and permit the firearm to be discharged. a hammer pivotably mounted about a hammer axis ; a sear pivotably mounted about a sear axis , wherein the sear comprises a first hook operable to provide a primary interface with the hammer ; an actuator comprising an actuator base and an actuator arm extending radially outwardly from the actuator base , wherein the actuator base is pivotably mounted about an actuator axis ; and wherein the sear further comprises a second hook operable to provide a secondary interface with the hammer and wherein, upon failure of the first hook , the second hook secures the hammer and prevents discharge of the firearm characterized in that the actuator arm comprises a notch and further comprising a trigger operable to rotate the actuator about the actuator axis to disengage the second hook of the sear from the notch of the actuator arm , thereby permitting the first hook of the sear to release the hammer and permit the firearm to be discharged.
A resin composition for molding, comprising: a chlorinated vinyl chloride-based resin; a thermal stabilizer; and a polyalcohol and/or a partial ester of a polyalcohol obtained by reaction with at least one mono- or polycarboxylic acid, the chlorinated vinyl chloride-based resin having a chlorine content of 65% by weight or more and less than 72% by weight, as measured in accordance with JIS K 7229, the chlorinated vinyl chloride-based resin having, as evaluated by NMR as set out in the description and based on the total number of moles of a structural unit (a) -CCl 2 -, a structural unit (b) -CHCl-, and a structural unit (c) -CH 2 -, a proportion of the structural unit (a) of 17.5 mol% or less, a proportion of the structural unit (b) of 46.0 mol% or more, and a proportion of the structural unit (c) of 37.0 mol% or less, the thermal stabilizer containing a compound represented by the formula Ca 1-x Zn x (OH) 2 where x satisfies the inequality 0 < x < 1 or a compound represented by the formula Ca 1-y Zn y O where y satisfies the inequality 0 < y < 1, and wherein the resin composition for molding contains the polyalcohol and/or the partial ester of a polyalcohol in a total amount within the range of 0.05 to 3 parts by weight based on 100 parts by weight of the chlorinated vinyl chloride-based resin. a chlorinated vinyl chloride-based resin; a thermal stabilizer; and a polyalcohol and/or a partial ester of a polyalcohol obtained by reaction with at least one mono- or polycarboxylic acid, the chlorinated vinyl chloride-based resin having a chlorine content of 65% by weight or more and less than 72% by weight, as measured in accordance with JIS K 7229, the chlorinated vinyl chloride-based resin having, as evaluated by NMR as set out in the description and based on the total number of moles of a structural unit (a) -CCl 2 -, a structural unit (b) -CHCl-, and a structural unit (c) -CH 2 -, a proportion of the structural unit (a) of 17.5 mol% or less, a proportion of the structural unit (b) of 46.0 mol% or more, and a proportion of the structural unit (c) of 37.0 mol% or less, the thermal stabilizer containing a compound represented by the formula Ca 1-x Zn x (OH) 2 where x satisfies the inequality 0 < x < 1 or a compound represented by the formula Ca 1-y Zn y O where y satisfies the inequality 0 < y < 1, and wherein the resin composition for molding contains the polyalcohol and/or the partial ester of a polyalcohol in a total amount within the range of 0.05 to 3 parts by weight based on 100 parts by weight of the chlorinated vinyl chloride-based resin.
Naringenin for use in a method of preventing and/or treating abdominal aortic aneurysms.
A contactor device , comprising: a first fixed contact element connected to a first terminal of the contactor device and a second fixed contact element connected to a second terminal of the contactor device , the pair of fixed contact elements having at least one fixed contact ; a movable contact element having at least one movable contact ; a casing for supporting and protecting said fixed and movable contact elements ; a moving mechanism for moving said movable contact element to move said at least one movable contact into contact to said at least one fixed contact to electrically connect said first and second fixed contact elements to one another or apart from said at least one fixed contact to electrically separate said first and second fixed contact elements from one another; a driving means for activating said moving mechanism ; and an indicator means for indicating a connecting status of said first and second fixed contact elements , characterized in that said moving mechanism is arranged and configured such that it is acting on said indicator means when it is activated by said driving means to move said movable contact element to move said at least one movable contact into contact to said at least one fixed contact , and wherein an actuator is arranged between said moving mechanism and said indicator means to receive an action of said moving mechanism and to act on a button of said indicator means when receiving the action of said moving mechanism , wherein said actuator is preferably biased to a position not acting on said button of said indicator means . a first fixed contact element connected to a first terminal of the contactor device and a second fixed contact element connected to a second terminal of the contactor device , the pair of fixed contact elements having at least one fixed contact ; a movable contact element having at least one movable contact ; a casing for supporting and protecting said fixed and movable contact elements ; a moving mechanism for moving said movable contact element to move said at least one movable contact into contact to said at least one fixed contact to electrically connect said first and second fixed contact elements to one another or apart from said at least one fixed contact to electrically separate said first and second fixed contact elements from one another; a driving means for activating said moving mechanism ; and an indicator means for indicating a connecting status of said first and second fixed contact elements , characterized in that said moving mechanism is arranged and configured such that it is acting on said indicator means when it is activated by said driving means to move said movable contact element to move said at least one movable contact into contact to said at least one fixed contact , and wherein an actuator is arranged between said moving mechanism and said indicator means to receive an action of said moving mechanism and to act on a button of said indicator means when receiving the action of said moving mechanism , wherein said actuator is preferably biased to a position not acting on said button of said indicator means .
A specimen container comprising: a vessel comprising a reservoir and a specimen collection region; a sleeve located within the vessel and moveable in the direction of the reservoir; wherein movement of the sleeve in the direction of the reservoir results in the specimen collection region and reservoir being brought into fluid communication with each other, wherein the vessel comprises at least one abutment surface and the sleeve comprises at least one leg portion arranged to contact the at least one abutment surface; the specimen container further comprising: a lid adapted to make closing contact with the vessel ; wherein the sleeve has a first configuration in which movement towards the reservoir is prevented, and a second configuration in which movement towards the reservoir can occur, the sleeve being arranged such that it is biased towards the first configuration and is movable from the first configuration to the second configuration when it operably interacts with the lid as said lid makes closing contact with the vessel . a vessel comprising a reservoir and a specimen collection region; a sleeve located within the vessel and moveable in the direction of the reservoir; wherein movement of the sleeve in the direction of the reservoir results in the specimen collection region and reservoir being brought into fluid communication with each other, wherein the vessel comprises at least one abutment surface and the sleeve comprises at least one leg portion arranged to contact the at least one abutment surface; the specimen container further comprising: a lid adapted to make closing contact with the vessel ; wherein the sleeve has a first configuration in which movement towards the reservoir is prevented, and a second configuration in which movement towards the reservoir can occur, the sleeve being arranged such that it is biased towards the first configuration and is movable from the first configuration to the second configuration when it operably interacts with the lid as said lid makes closing contact with the vessel . a lid adapted to make closing contact with the vessel ; wherein the sleeve has a first configuration in which movement towards the reservoir is prevented, and a second configuration in which movement towards the reservoir can occur, the sleeve being arranged such that it is biased towards the first configuration and is movable from the first configuration to the second configuration when it operably interacts with the lid as said lid makes closing contact with the vessel .
A measurement system for a dry powder agent comprising: a nozzle to direct a dry powder agent from a powder feeder system ; an indicator operable to recognize a dry powder agent discharge event; and a control system operable to compute a velocity of the dry powder agent, a sensor head , wherein the nozzle is arranged to direct the dry powder agent downstream to the sensor head ; wherein the control system is operable to compute the velocity of the dry powder agent by dividing the distance between the indicator and the sensor head with a time it takes the dry powder agent to initially pass from the indicator to the sensor head; and characterised in that the control system is operable to calibrate the powder feeder system based on the computed velocity by selecting a high-flow calibration curve or a low-flow calibration curve. a nozzle to direct a dry powder agent from a powder feeder system ; an indicator operable to recognize a dry powder agent discharge event; and a control system operable to compute a velocity of the dry powder agent, a sensor head , wherein the nozzle is arranged to direct the dry powder agent downstream to the sensor head ; wherein the control system is operable to compute the velocity of the dry powder agent by dividing the distance between the indicator and the sensor head with a time it takes the dry powder agent to initially pass from the indicator to the sensor head; and characterised in that the control system is operable to calibrate the powder feeder system based on the computed velocity by selecting a high-flow calibration curve or a low-flow calibration curve.
Sensor for monitoring the parameters of rotation around its own axis and vibration of a steel rope during operation in cableway systems, comprising: a battery , indicator means of the state of charge of said battery , at least a LED indicator integrated in the sensor for diagnostic aim, a voltage control unit which provides a stabilized voltage, a detection unit of the rotation angles (Φ, γ) around its own axis (X) and of the vibrations of said steel rope , a microprocessor for collection activity and data transmission, said sensor being characterized in that it is housed in a portion obtained in the core of the steel rope .