mhurhangee/patent-ind-claim-en huggingface dataset:
A method for identifying a nucleic acid fragmentation pattern in a subject by analyzing cell-free deoxyribonucleic acid (DNA) fragments in a biological sample from the subject, the cell-free DNA fragments originating from normal cells and potentially from disease cells, comprising: (a) taking a biological sample obtained from the subject, (b) enriching the biological sample for a set of cell-free DNA fragments having ends that are mappable to one or more loci associated with a disease, wherein the disease is tumor, and wherein the enriching comprises hybridizing at least one probe to one or each end of the cell-free DNA fragment, wherein the probe comprises a given sequence that is complementary to at least one end of the cell-free DNA fragment, and wherein each nucleotide of the given sequence of the probe hybridizes with the cell-free DNA fragment; (c) subjecting the set of cell-free DNA fragments enriched in (b) or derivatives thereof to sequencing to obtain a plurality of sequences; (d) aligning the plurality of sequences to a reference to determine genomic positions for the plurality of sequences, the genomic positions including positions corresponding to the one or each ends of the cell-free DNA fragment thereby indicating fragmentation sites of the cell-free DNA; and (e) identifying a set of loci with specific fragmentation patterns corresponding to said fragmentation sites in the plurality of sequences, wherein the set of loci correspond to the one or more loci associated with a disease, wherein the disease is tumor. (a) taking a biological sample obtained from the subject, (b) enriching the biological sample for a set of cell-free DNA fragments having ends that are mappable to one or more loci associated with a disease, wherein the disease is tumor, and wherein the enriching comprises hybridizing at least one probe to one or each end of the cell-free DNA fragment, wherein the probe comprises a given sequence that is complementary to at least one end of the cell-free DNA fragment, and wherein each nucleotide of the given sequence of the probe hybridizes with the cell-free DNA fragment; (c) subjecting the set of cell-free DNA fragments enriched in (b) or derivatives thereof to sequencing to obtain a plurality of sequences; (d) aligning the plurality of sequences to a reference to determine genomic positions for the plurality of sequences, the genomic positions including positions corresponding to the one or each ends of the cell-free DNA fragment thereby indicating fragmentation sites of the cell-free DNA; and (e) identifying a set of loci with specific fragmentation patterns corresponding to said fragmentation sites in the plurality of sequences, wherein the set of loci correspond to the one or more loci associated with a disease, wherein the disease is tumor.
A hatch operating mechanism arranged to control opening and closing movements of a hatch (202; 302; 402) covering an opening in a vehicle the mechanism comprising; - a first and a second arm (211, 221; 311, 321; 411, 421), which are rotatably attached to the vehicle at a first end and rotatably attached onto the hatch at a second end; characterized in - that a first and a second connecting element (214, 224; 314, 324; 414, 424) are arranged extending between and displaceable relative to a pair of spaced apart, parallel guide means (216, 226, 217, 227; 316, 317; 416, 417) fixed to the hatch (202; 302; 402), wherein the second ends of the first and second arms (211, 221; 311, 321; 411, 421) are rotatably attached to a respective first and second connecting element (214, 224; 314, 324; 414, 424), - that the first and the second arm (211, 221; 311, 321; 411, 421) are located in mirrored positions relative to a plane of symmetry (P) at right angles to the guide means (216, 226, 217, 227; 316, 317; 416, 417); - that the first ends of the arms (211, 221; 311, 321; 411, 421) are arranged in a common plane, which first ends have axes arranged at equal and opposite angles relative the plane of symmetry (P); that the first and second arms (211, 221; 311, 321; 411, 421) are simultaneously rotatable in opposite directions about their first ends over an arcuate path; and that the connecting elements (214, 224; 314, 324; 414, 424) are arranged to execute a reciprocating movement along the guide means (216, 226; 217, 227) during the rotation of the first and second arms over the arcuate path. - a first and a second arm (211, 221; 311, 321; 411, 421), which are rotatably attached to the vehicle at a first end and rotatably attached onto the hatch at a second end; - that a first and a second connecting element (214, 224; 314, 324; 414, 424) are arranged extending between and displaceable relative to a pair of spaced apart, parallel guide means (216, 226, 217, 227; 316, 317; 416, 417) fixed to the hatch (202; 302; 402), wherein the second ends of the first and second arms (211, 221; 311, 321; 411, 421) are rotatably attached to a respective first and second connecting element (214, 224; 314, 324; 414, 424), - that the first and the second arm (211, 221; 311, 321; 411, 421) are located in mirrored positions relative to a plane of symmetry (P) at right angles to the guide means (216, 226, 217, 227; 316, 317; 416, 417); - that the first ends of the arms (211, 221; 311, 321; 411, 421) are arranged in a common plane, which first ends have axes arranged at equal and opposite angles relative the plane of symmetry (P);
A method for processing data in a network configured to supply several user devices by a plurality of transport networks (203-207) within an area, wherein in the area two or more of the plurality of transport networks (203-207) are available for serving the user devices , - wherein a plurality of parameters is provided by a network component or the plurality of parameters is provided by a user device of a user and by the network component, - wherein a transport network of the two or more available transport networks of the plurality of transport networks (203-207) is selected and/or adjusted by a network function based on said plurality of parameters, a history of traffic regarding service requests depending on the area and a history of traffic regarding the user, - wherein the selected and/or adjusted transport network comprises xDSL functionality, and - wherein the plurality of parameters provided comprises information regarding the location of the user device of the user and a number of users or subscribers that require a same or different services within the area. - wherein a plurality of parameters is provided by a network component or the plurality of parameters is provided by a user device of a user and by the network component, - wherein a transport network of the two or more available transport networks of the plurality of transport networks (203-207) is selected and/or adjusted by a network function based on said plurality of parameters, a history of traffic regarding service requests depending on the area and a history of traffic regarding the user, - wherein the selected and/or adjusted transport network comprises xDSL functionality, and - wherein the plurality of parameters provided comprises information regarding the location of the user device of the user and a number of users or subscribers that require a same or different services within the area.
A systolic array for computational processing, the systolic array comprising: an array of processing elements "PEs" arranged in rows and columns , wherein each of the PEs includes at least one multiplier-accumulator "MAC" ; logic to perform a horizontal shift operation, wherein the horizontal shift operation is performed across the entire systolic array , logic to mark columns of PEs as enabled or disabled; controllable data edge indications associated with the columns ; and controllable column valid indications associated with the columns, wherein the systolic array is horizontally divided into horizontal groups , and wherein when performing the horizontal shift operation, valid data that crosses from a first column of PEs of a first horizontal group to a second column of PEs of a second horizontal group is invalidated, wherein the first horizontal group is adjacent to the second horizontal group, wherein data is validated by enabling the PEs the data is shifted to, and invalidated by, disabling the PEs the data is shifted to, wherein the controllable data edge indications are for indicating a horizontal position of edges between the horizontal groups, wherein the controllable column valid indications are for enabling and disabling the columns, and wherein disabling and enabling the data that crosses from the first horizontal group to the second horizontal group is performed according to a value of an associated column valid indication and associated data edge indication. an array of processing elements "PEs" arranged in rows and columns , wherein each of the PEs includes at least one multiplier-accumulator "MAC" ; logic to perform a horizontal shift operation, wherein the horizontal shift operation is performed across the entire systolic array , logic to mark columns of PEs as enabled or disabled; controllable data edge indications associated with the columns ; and controllable column valid indications associated with the columns, wherein the systolic array is horizontally divided into horizontal groups , and wherein when performing the horizontal shift operation, valid data that crosses from a first column of PEs of a first horizontal group to a second column of PEs of a second horizontal group is invalidated, wherein the first horizontal group is adjacent to the second horizontal group, wherein data is validated by enabling the PEs the data is shifted to, and invalidated by, disabling the PEs the data is shifted to, wherein the controllable data edge indications are for indicating a horizontal position of edges between the horizontal groups, wherein the controllable column valid indications are for enabling and disabling the columns, and wherein disabling and enabling the data that crosses from the first horizontal group to the second horizontal group is performed according to a value of an associated column valid indication and associated data edge indication.
A composition for the preparation of a transparent, non-elastomeric optical article, the composition comprising: a polyisocyanate component comprising one or more different polyisocyanates; and a component that is reactive with isocyanates, comprising: (a) optionally at least one polyol having a number average molecular weight greater than 500; (b) (i) at least one polyol and/or polythiol and (ii) at least one compound containing both amine and hydroxyl functional groups, wherein the compound (ii) has a number average molecular weight less than 500; and optionally a urethanation catalyst. a polyisocyanate component comprising one or more different polyisocyanates; and a component that is reactive with isocyanates, comprising: (a) optionally at least one polyol having a number average molecular weight greater than 500; (b) (i) at least one polyol and/or polythiol and (ii) at least one compound containing both amine and hydroxyl functional groups, wherein the compound (ii) has a number average molecular weight less than 500; and optionally (a) optionally at least one polyol having a number average molecular weight greater than 500; (b) (i) at least one polyol and/or polythiol and (ii) at least one compound containing both amine and hydroxyl functional groups, wherein the compound (ii) has a number average molecular weight less than 500; and optionally a urethanation catalyst.
A method of multiple level resource reservation for a deterministic data stream in a peer-to-peer protocol, comprising: making, by a first node , a resource reservation request to a second node at a first protocol layer ; receiving, at the first node , a reservation acknowledgement from the second node at the first protocol layer , in response to the resource reservation request ; and subsequently making, by the first node , a resource reservation request to the second node at a second protocol layer , wherein the second protocol layer is higher than the first protocol layer ; wherein, if the resource reservation request at the first protocol layer fails, then failing the resource reservation at the second protocol layer ; wherein if the resource reservation request at the second protocol layer fails, then withdrawing the resource reservation at the first protocol layer . making, by a first node , a resource reservation request to a second node at a first protocol layer ; receiving, at the first node , a reservation acknowledgement from the second node at the first protocol layer , in response to the resource reservation request ; and subsequently making, by the first node , a resource reservation request to the second node at a second protocol layer , wherein the second protocol layer is higher than the first protocol layer ; wherein, if the resource reservation request at the first protocol layer fails, then failing the resource reservation at the second protocol layer ; wherein if the resource reservation request at the second protocol layer fails, then withdrawing the resource reservation at the first protocol layer .
Vehicle seat comprising at least one frame which forms an external contour of the vehicle seat , wherein a seat shell is disposed on the frame on a front side of the vehicle seat ; wherein the seat shell is formed from a thermally bonded non-woven fabric; wherein at least one reinforcing element is fastened to a front seat edge and to an upper seat end on the frame , and wherein the reinforcing element extends by way of at least one portion (11.1) between the front seat edge and the upper seat end on a front side (7.1) of the seat shell , and by way of at least one further portion (11.2) on a rear side (7.2) of the seat shell .
A method for fabricating a denture base with a cutting machine , the method comprising: a preparation step (S10) of preparing a cutting target mold including: a molding space being surrounded by a bottom wall and an outer frame (41 to 44) extending upward from the bottom wall ; an attachment step (S20) of disposing a retention member in the molding space , the retention member being attached to the cutting machine directly or indirectly; an integration step (S30, S90) of injecting a denture base material into the molding space and hardening the denture base material to obtain a hardened object of the denture base material , thereby obtaining a cutting target in which the hardened object of the denture base material and the retention member are integrated; wherein the retention member is made of a material having a hardness greater than that of the hardened object of the denture base material or having a bending strength larger than that of the hardened object of the denture base material ; a detachment step (S60) of detaching the cutting target from the cutting target mold ; a first fabrication step (S70) of attaching the cutting target to the cutting machine with the retention member interposed therebetween and then cutting a portion of the hardened object with the cutting machine ; and a second fabrication step (S80) of detaching the retention member from the hardened object after the first fabrication step (S70). a preparation step (S10) of preparing a cutting target mold including: a molding space being surrounded by a bottom wall and an outer frame (41 to 44) extending upward from the bottom wall ; an attachment step (S20) of disposing a retention member in the molding space , the retention member being attached to the cutting machine directly or indirectly; an integration step (S30, S90) of injecting a denture base material into the molding space and hardening the denture base material to obtain a hardened object of the denture base material , thereby obtaining a cutting target in which the hardened object of the denture base material and the retention member are integrated; wherein the retention member is made of a material having a hardness greater than that of the hardened object of the denture base material or having a bending strength larger than that of the hardened object of the denture base material ; a detachment step (S60) of detaching the cutting target from the cutting target mold ; a first fabrication step (S70) of attaching the cutting target to the cutting machine with the retention member interposed therebetween and then cutting a portion of the hardened object with the cutting machine ; and a second fabrication step (S80) of detaching the retention member from the hardened object after the first fabrication step (S70).
A double-pane window insulating system comprising: a double-pane window including a chamber formed between a pair of window panes, a bead inlet through which a plurality of beads and air are introduced into the chamber , a bead outlet through which the plurality of beads and the air received in the chamber are discharged, and an air entrance/exit opening through which air enters or exits the chamber ; and a bead discharge means configured to discharge the plurality of beads received in the chamber to the bead outlet , characterized in that the bead discharge means further includes: a rotatable screw shaft having a helical shape and provided on the bottom of the chamber so as to be directed toward the bead outlet ; and a screw shaft drive motor configured to rotate the screw shaft. a double-pane window including a chamber formed between a pair of window panes, a bead inlet through which a plurality of beads and air are introduced into the chamber , a bead outlet through which the plurality of beads and the air received in the chamber are discharged, and an air entrance/exit opening through which air enters or exits the chamber ; and a bead discharge means configured to discharge the plurality of beads received in the chamber to the bead outlet , characterized in that the bead discharge means further includes: a rotatable screw shaft having a helical shape and provided on the bottom of the chamber so as to be directed toward the bead outlet ; and a screw shaft drive motor configured to rotate the screw shaft. a rotatable screw shaft having a helical shape and provided on the bottom of the chamber so as to be directed toward the bead outlet ; and a screw shaft drive motor configured to rotate the screw shaft.
An indoor unit for air conditioner comprising: a cross flow fan configured to form an air flow of suctioning indoor air from an air inlet port and blowing out the air from an air outlet port ; a fan motor adapted to drive the cross flow fan ; a holding case configured to hold the fan motor therein; a fitting portion to which the holding case holding the fan motor therein is fitted; a vibration damping member that is accommodated inside the holding case along with the fan motor and adapted to absorb vibration generated when the fan motor is driven; a compressing section that adapted to compress the vibration damping member inside the holding case with the holding case holding the fan motor therein being fitted to the fitting portion ; characterized in that the compressing section having slits . a cross flow fan configured to form an air flow of suctioning indoor air from an air inlet port and blowing out the air from an air outlet port ; a fan motor adapted to drive the cross flow fan ; a holding case configured to hold the fan motor therein; a fitting portion to which the holding case holding the fan motor therein is fitted; a vibration damping member that is accommodated inside the holding case along with the fan motor and adapted to absorb vibration generated when the fan motor is driven; a compressing section that adapted to compress the vibration damping member inside the holding case with the holding case holding the fan motor therein being fitted to the fitting portion ; characterized in that the compressing section having slits .
An apparatus comprising: a housing ; a developer roller disposed in the housing to receive ink and transfer a portion of the ink to a photoconductive member ; an electrode disposed in the housing to create a potential bias with the developer roller to transfer the ink to the developer roller ; a squeegee roller disposed in the housing to rotate and regulate a film thickness of ink on the developer roller , wherein an ink flow path extends through a gap between the squeegee roller and the electrode ; and a flow restriction member to create a flow restriction in the ink flow path to inhibit ink flow streaks from being formed on the developer roller ; wherein the flow restriction member comprises an electrically non-conductive or dielectric plate attached to the electrode to reduce a gap width of the ink flow path (281; 525) through the gap between the squeegee roller and the electrode . a housing ; a developer roller disposed in the housing to receive ink and transfer a portion of the ink to a photoconductive member ; an electrode disposed in the housing to create a potential bias with the developer roller to transfer the ink to the developer roller ; a squeegee roller disposed in the housing to rotate and regulate a film thickness of ink on the developer roller , wherein an ink flow path extends through a gap between the squeegee roller and the electrode ; and a flow restriction member to create a flow restriction in the ink flow path to inhibit ink flow streaks from being formed on the developer roller ; wherein the flow restriction member comprises an electrically non-conductive or dielectric plate attached to the electrode to reduce a gap width of the ink flow path (281; 525) through the gap between the squeegee roller and the electrode .
Line-guiding device with a plurality of links which are connected to one another in an articulated fashion and form a loop consisting of an upper run , a deflection region , and a lower run , wherein neighbouring links can be pivoted relative to each other about a respective pivot axis , wherein the pivot axes are, at least in the case of some of the links , arranged closer to a loop inner side than a loop outer side , wherein the links each have two side tabs situated opposite each other, wherein side tabs of neighbouring links form at least one running surface on the loop inner side , wherein at least some of the links have a respective roller projecting from the running surface , wherein the upper run and the lower run can bear against each other via the running surface in such a way that the upper run and the lower run can be moved relative to each other by means of the rollers , characterized in that the running surface is interrupted at at least some of the links by a plurality of depressions .
Part of a motor vehicle made from plastic material, comprising at least one wall intended to be welded to a bodywork element , said wall comprising at least one protruding element defining a weld surface intended to form a point of contact with said bodywork element , characterised in that the part comprises, around said protruding element , at least one stress relief area for relieving stresses experienced by the protruding element .