mhurhangee/patent-ind-claim-en huggingface dataset:
A method of detecting a target in a sample, the method comprising: contacting the sample with a first affinity agent linked to a solid support, wherein the first affinity agent specifically binds to the target, if present, thereby forming a target bound to the first affinity agent; separating the target bound to the first affinity agent from unbound material in the sample based on the presence or absence of the solid support, thereby generating a separated sample comprising the target bound to the first affinity agent; contacting the separated sample with a second affinity agent comprising a first label and a third affinity agent comprising a second label, wherein the second and third affinity agents specifically bind to the target, thereby forming a target-labeled affinity agent complex; and wherein the first label generates a first signal and the second label generates a second signal and the first signal and the second signal are distinguishable; separating the target-labeled affinity agent complex from uncomplexed second and third affinity agents based on the presence or absence of the solid support, thereby generating a separated target-labeled affinity agent complex; partitioning at least the separated target-labeled affinity agent complex into a plurality of partitions; and detecting the presence of the target in the sample by detecting the distinguishable first and second signals from the first and second labels co-localized in at least one same partition. contacting the sample with a first affinity agent linked to a solid support, wherein the first affinity agent specifically binds to the target, if present, thereby forming a target bound to the first affinity agent; separating the target bound to the first affinity agent from unbound material in the sample based on the presence or absence of the solid support, thereby generating a separated sample comprising the target bound to the first affinity agent; contacting the separated sample with a second affinity agent comprising a first label and a third affinity agent comprising a second label, wherein the second and third affinity agents specifically bind to the target, thereby forming a target-labeled affinity agent complex; and wherein the first label generates a first signal and the second label generates a second signal and the first signal and the second signal are distinguishable; separating the target-labeled affinity agent complex from uncomplexed second and third affinity agents based on the presence or absence of the solid support, thereby generating a separated target-labeled affinity agent complex; partitioning at least the separated target-labeled affinity agent complex into a plurality of partitions; and detecting the presence of the target in the sample by detecting the distinguishable first and second signals from the first and second labels co-localized in at least one same partition.
A respiratory assistance apparatus having an integrated cooling system and comprising an enclosure accommodating a fan that has an electric motor coupled to an impeller and having an inlet and at least two air outlets , a gas outlet for the patient and a cooling air outlet of the electric motor which has a longitudinal axis (X'X) and is delimited by a casing having a longitudinal tubular wall and transverse end flanges , said motor comprising a stator mounted on the tubular wall of the casing and a rotor mounted on a longitudinal motor shaft passing through at least one of the transverse flanges of the casing via guide bearings in order to rotate the impeller accommodated in an air-receiving volute , in which apparatus the air circulated by the impeller blades is pulsed toward the gas outlet for the patient via an outlet duct coupled to the volute , a fraction of this air being drawn from the volute and flowing between the rotor and the stator of the motor through the cooling system that comprises openings formed in each of the transverse flanges , and an air discharge pipe is coupled both to the tubular wall of the casing and to the cooling air outlet of the enclosure , characterized in that , in said apparatus, an air flow (F0) coming directly from the inlet of the enclosure is suctioned (arrows F1) into the volute by the rotation of the impeller blades , said air flows (arrows F1) coming directly from the space (E1) located above the volute , and in that , in said system, sealing washers , secured to the transverse flanges so as to cover said flanges, are centered on the motor shaft and are large enough for said washers to protect the bearings from the air (F3, F4, F5) flowing through and leaving the motor by extending as close to the motor shaft as possible without generating friction or closing off the openings of the cooling system.
A system for heating a target region , the system comprising: an ultrasound transducer comprising a plurality of transducer elements ; and a controller , wherein the controller is configured to: (a) divide the ultrasound transducer into a plurality of sub-regions, each sub-region comprising a plurality of transducer elements; (b) identify a location of at least one hot spot in at least one of the target region or a region surrounding the target region during an ultrasound sonication process, the hot spot having an energy density above a predefined acceptable level; (c) based at least in part on the identified location of the hot spot, compute an activation and deactivation pattern of each sub-region that will reduce the energy density of the hot spot to the predefined acceptable level; and (d) operate each sub-region of the transducer elements based at least in part on the activation and deactivation pattern. an ultrasound transducer comprising a plurality of transducer elements ; and a controller , wherein the controller is configured to: (a) divide the ultrasound transducer into a plurality of sub-regions, each sub-region comprising a plurality of transducer elements; (b) identify a location of at least one hot spot in at least one of the target region or a region surrounding the target region during an ultrasound sonication process, the hot spot having an energy density above a predefined acceptable level; (c) based at least in part on the identified location of the hot spot, compute an activation and deactivation pattern of each sub-region that will reduce the energy density of the hot spot to the predefined acceptable level; and (d) operate each sub-region of the transducer elements based at least in part on the activation and deactivation pattern. (a) divide the ultrasound transducer into a plurality of sub-regions, each sub-region comprising a plurality of transducer elements; (b) identify a location of at least one hot spot in at least one of the target region or a region surrounding the target region during an ultrasound sonication process, the hot spot having an energy density above a predefined acceptable level; (c) based at least in part on the identified location of the hot spot, compute an activation and deactivation pattern of each sub-region that will reduce the energy density of the hot spot to the predefined acceptable level; and (d) operate each sub-region of the transducer elements based at least in part on the activation and deactivation pattern.
A computer-implemented method comprising: receiving, by a processing computer from a transport computer or a resource provider computer , an authorization request message for a transaction and a session identifier, the session identifier generated by the resource provider computer and associated with data for one or more interactions by a user associated with the transaction and stored in a supplemental database ; obtaining, by the processing computer and from the supplemental database , a portion of pre-analyzed data about the user and the one or more interactions based at least in part on the session identifier; performing, by the processing computer , a risk analysis for the transaction using the portion of the pre-analyzed data to generate a value, the value representing a likelihood of a fraudulent transaction for the transaction; modifying, by the processing computer , the authorization request message to include the portion of the pre-analyzed data and the value; transmitting, by the processing computer and to an authorizing computer , the modified authorization request message; and transmitting, by the processing computer to the transport computer , an authorization response message from the authorizing computer , the authorizing computer generating the authorization response message based on the modified authorization request message, the authorization response message approving or declining the transaction. receiving, by a processing computer from a transport computer or a resource provider computer , an authorization request message for a transaction and a session identifier, the session identifier generated by the resource provider computer and associated with data for one or more interactions by a user associated with the transaction and stored in a supplemental database ; obtaining, by the processing computer and from the supplemental database , a portion of pre-analyzed data about the user and the one or more interactions based at least in part on the session identifier; performing, by the processing computer , a risk analysis for the transaction using the portion of the pre-analyzed data to generate a value, the value representing a likelihood of a fraudulent transaction for the transaction; modifying, by the processing computer , the authorization request message to include the portion of the pre-analyzed data and the value; transmitting, by the processing computer and to an authorizing computer , the modified authorization request message; and transmitting, by the processing computer to the transport computer , an authorization response message from the authorizing computer , the authorizing computer generating the authorization response message based on the modified authorization request message, the authorization response message approving or declining the transaction.
A cohesive injectable dermal filler composition comprising a crosslinked hyaluronic acid-based polymer and at least one phenolic antioxidant, wherein the antioxidant is a water-soluble glycosylated derivative of a non-water-soluble antioxidant.
A re-encryption key generation device comprising: a randomization unit adapted to set a random number in a decryption key tdk x in which a key attribute x is set and set a random number in a tag tg φ used to decrypt a ciphertext with the decryption key tdk x , so as to generate a decryption key tdk x ^ and a tag tg φ ^; an encryption key generation unit adapted to encrypt the decryption key tdk x ^ generated by the randomization unit by an attribute-based encryption scheme using a ciphertext attribute y', so as to generate an encryption key act y' ; and a re-encryption key output unit adapted to output a re-encryption key rk x,y' including the encryption key act y' generated by the encryption key generation unit and the tag tg φ ^ generated by the randomization unit . a randomization unit adapted to set a random number in a decryption key tdk x in which a key attribute x is set and set a random number in a tag tg φ used to decrypt a ciphertext with the decryption key tdk x , so as to generate a decryption key tdk x ^ and a tag tg φ ^; an encryption key generation unit adapted to encrypt the decryption key tdk x ^ generated by the randomization unit by an attribute-based encryption scheme using a ciphertext attribute y', so as to generate an encryption key act y' ; and a re-encryption key output unit adapted to output a re-encryption key rk x,y' including the encryption key act y' generated by the encryption key generation unit and the tag tg φ ^ generated by the randomization unit .
A system comprising: a laser light source configured to emit a laser beam to an object; and a laser beam steering device configured to steer the emitted laser beam incident thereon, comprising: a refractive index change layer having a refractive index that changes based on an electrical signal; at least one antenna pattern disposed above the refractive index change layer; a further layer disposed under the refractive index change layer; and a driver configured to apply the electrical signal to the refractive index change layer; characterized in that the further layer is a wavelength selection layer whose carrier density is such as to cause the layer to resonate at the wavelength of the laser beam. a laser light source configured to emit a laser beam to an object; and a laser beam steering device configured to steer the emitted laser beam incident thereon, comprising: a refractive index change layer having a refractive index that changes based on an electrical signal; at least one antenna pattern disposed above the refractive index change layer; a further layer disposed under the refractive index change layer; and a driver configured to apply the electrical signal to the refractive index change layer; a refractive index change layer having a refractive index that changes based on an electrical signal; at least one antenna pattern disposed above the refractive index change layer; a further layer disposed under the refractive index change layer; and a driver configured to apply the electrical signal to the refractive index change layer; characterized in that the further layer is a wavelength selection layer whose carrier density is such as to cause the layer to resonate at the wavelength of the laser beam.
A receiver comprising: a time-interleaved charge sampler comprising a charge sampler switch in series with a charge sampler capacitor; and a current buffer configured to drive the time-interleaved charge sampler, wherein the current buffer is differential and drives a first differential input path and a second differential input path of the time-interleaved charge sampler; and a reset switch coupled between the first differential input path and the second differential input path of the time-interleaved charge sampler. a time-interleaved charge sampler comprising a charge sampler switch in series with a charge sampler capacitor; and a current buffer configured to drive the time-interleaved charge sampler, wherein the current buffer is differential and drives a first differential input path and a second differential input path of the time-interleaved charge sampler; and a reset switch coupled between the first differential input path and the second differential input path of the time-interleaved charge sampler.
A space active optical cable (SAOC) comprising: a cable comprising one or more optical fibers; and two or more electrical transceivers on opposing ends of the cable and interconnected by the cable , each of the electrical transceivers of the two or more electrical transceivers comprising: an enclosure enclosing: one or more light sources , one or more light detectors , and control electronics enclosed in the enclosure; and a coupling medium configured to couple light into and out of the one or more optical fibers, a radio-frequency (RF) modulator and a local oscillator (LO) modulator configured to modulate light generated by the one or more light sources; and a light processor coupled to the one or more light sources , the RF modulator and the LO modulator and comprising a filter and lock-diode unit configured to generate a heterodyne output light, and wherein the enclosure provides a suitable heat propagation and electromagnetic interference shielding, and the cable and the two or more electrical transceivers are radiation resistant. a cable comprising one or more optical fibers; and two or more electrical transceivers on opposing ends of the cable and interconnected by the cable , each of the electrical transceivers of the two or more electrical transceivers comprising: an enclosure enclosing: one or more light sources , one or more light detectors , and control electronics enclosed in the enclosure; and a coupling medium configured to couple light into and out of the one or more optical fibers, a radio-frequency (RF) modulator and a local oscillator (LO) modulator configured to modulate light generated by the one or more light sources; and a light processor coupled to the one or more light sources , the RF modulator and the LO modulator and comprising a filter and lock-diode unit configured to generate a heterodyne output light, and wherein the enclosure provides a suitable heat propagation and electromagnetic interference shielding, and the cable and the two or more electrical transceivers are radiation resistant. one or more light sources , one or more light detectors , and control electronics enclosed in the enclosure; and a coupling medium configured to couple light into and out of the one or more optical fibers, a radio-frequency (RF) modulator and a local oscillator (LO) modulator configured to modulate light generated by the one or more light sources; and a light processor coupled to the one or more light sources , the RF modulator and the LO modulator and comprising a filter and lock-diode unit configured to generate a heterodyne output light, and wherein the enclosure provides a suitable heat propagation and electromagnetic interference shielding, and the cable and the two or more electrical transceivers are radiation resistant.
A linear compressor , comprising: a shell ; a cylinder provided in the shell to define a compression space for a refrigerant; a piston reciprocated in an axial direction within the cylinder ; a discharge valve provided at one end of the cylinder to selectively discharge the refrigerant compressed in the compression space; and at least one nozzle provided disposed in the cylinder and through which at least a portion of the refrigerant discharged through the discharge valve is flowable, wherein the at least one nozzle comprises an inlet , through which the refrigerant is introduced, and an outlet having a diameter less than a diameter of the inlet , wherein the linear compressor further comprises: at least one gas inflow recessed from an outer circumferential surface of the cylinder , wherein the least one gas inflow communicates with the at least one nozzle ; and a filter member disposed in the at least one gas inflow , characterized in that the filter member comprises a thread that is wound several times around the at least one gas inflow. a shell ; a cylinder provided in the shell to define a compression space for a refrigerant; a piston reciprocated in an axial direction within the cylinder ; a discharge valve provided at one end of the cylinder to selectively discharge the refrigerant compressed in the compression space; and at least one nozzle provided disposed in the cylinder and through which at least a portion of the refrigerant discharged through the discharge valve is flowable, wherein the at least one nozzle comprises an inlet , through which the refrigerant is introduced, and an outlet having a diameter less than a diameter of the inlet , wherein the linear compressor further comprises: at least one gas inflow recessed from an outer circumferential surface of the cylinder , wherein the least one gas inflow communicates with the at least one nozzle ; and a filter member disposed in the at least one gas inflow , characterized in that the filter member comprises a thread that is wound several times around the at least one gas inflow. at least one gas inflow recessed from an outer circumferential surface of the cylinder , wherein the least one gas inflow communicates with the at least one nozzle ; and a filter member disposed in the at least one gas inflow , characterized in that the filter member comprises a thread that is wound several times around the at least one gas inflow.
A cell culture for obtaining an epithelial organoid, the cell culture comprising i) epithelial stem cells, or tissue fragments comprising said epithelial stem cells ii) a basal medium for animal or human cells, iii) a Bone Morphogenetic Protein (BMP) inhibitor, iv) a mitogenic growth factor selected from the group consisting of epidermal growth factor (EGF), transforming growth factor-alpha (TGF-alpha), basic fibroblast growth factor (bFGF), brain-derived neurotrophic factor (BDNF) and keratinocyte growth factor (KGF), v) at least one soluble culture enhancer, wherein said at least one culture enhancer induces correct polarization of the cells in said cell culture within the developing organoid, and vi) a Wnt agonist if said epithelial stem cells, or tissue fragments comprising said epithelial stem cells are healthy cells, wherein said at least one soluble culture enhancer in said cell culture is a laminin/entactin complex in a concentration between 0.2 mg/ml and 1 mg/ml. i) epithelial stem cells, or tissue fragments comprising said epithelial stem cells ii) a basal medium for animal or human cells, iii) a Bone Morphogenetic Protein (BMP) inhibitor, iv) a mitogenic growth factor selected from the group consisting of epidermal growth factor (EGF), transforming growth factor-alpha (TGF-alpha), basic fibroblast growth factor (bFGF), brain-derived neurotrophic factor (BDNF) and keratinocyte growth factor (KGF), v) at least one soluble culture enhancer, wherein said at least one culture enhancer induces correct polarization of the cells in said cell culture within the developing organoid, and vi) a Wnt agonist if said epithelial stem cells, or tissue fragments comprising said epithelial stem cells are healthy cells,
An instrument sterile drape comprising: a plastic sheet ; and an instrument sterile adapter (ISA) coupled to the plastic sheet , the ISA including a bottom plate located on a first side of the plastic sheet and a top plate located on a second side of the plastic sheet and joined to the bottom plate , the bottom plate including a mounting surface that provides a first datum plane for mounting the ISA on a carriage that includes actuators; characterised in that the bottom plate comprises a plurality of landing pads that extend through the top plate to provide a second datum plane for a surgical instrument coupled to the ISA such that the second datum plane and the mounting surface are opposing parallel surfaces on the bottom plate separated by a fixed distance. a plastic sheet ; and an instrument sterile adapter (ISA) coupled to the plastic sheet , the ISA including a bottom plate located on a first side of the plastic sheet and a top plate located on a second side of the plastic sheet and joined to the bottom plate , the bottom plate including a mounting surface that provides a first datum plane for mounting the ISA on a carriage that includes actuators; characterised in that the bottom plate comprises a plurality of landing pads that extend through the top plate to provide a second datum plane for a surgical instrument coupled to the ISA such that the second datum plane and the mounting surface are opposing parallel surfaces on the bottom plate separated by a fixed distance.