mhurhangee/patent-ind-claim-en huggingface dataset:
A UBE3A vector, comprising: a transcription initiation sequence, wherein the transcription initiation sequence is a cytomegalovirus chicken-beta actin hybrid promotor, or a human ubiquitin c promotor; a UBE3A sequence disposed downstream of the transcription initiation sequence, wherein the UBE3A sequence is SEQ ID NO: 6, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 15, a cDNA of SEQ ID NO: 7, a cDNA of SEQ ID NO: 14, or a nucleotide sequence possessing at least 95% sequence identity thereto; a secretion sequence disposed downstream of the transcription initiation sequence, wherein the secretion sequence is SEQ ID NO: 2, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, a cDNA of SEQ ID NO: 3, or a nucleotide sequence possessing at least 80% sequence identity thereto; and a cell uptake sequence disposed downstream of the transcription initiation sequence, wherein the cell uptake sequence is a cDNA of SEQ ID NO: 11, or a nucleotide sequence possessing at least 80% sequence identity thereto wherein a therapeutically effective amount of E6-associated protein (E6-AP) expressed by cells transfected with the UBE3A vector is secreted and taken up by cerebral cells with a deficiency in E6-AP expression. a transcription initiation sequence, wherein the transcription initiation sequence is a cytomegalovirus chicken-beta actin hybrid promotor, or a human ubiquitin c promotor; a UBE3A sequence disposed downstream of the transcription initiation sequence, wherein the UBE3A sequence is SEQ ID NO: 6, SEQ ID NO: 12, SEQ ID NO: 13, SEQ ID NO: 15, a cDNA of SEQ ID NO: 7, a cDNA of SEQ ID NO: 14, or a nucleotide sequence possessing at least 95% sequence identity thereto; a secretion sequence disposed downstream of the transcription initiation sequence, wherein the secretion sequence is SEQ ID NO: 2, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10, a cDNA of SEQ ID NO: 3, or a nucleotide sequence possessing at least 80% sequence identity thereto; and a cell uptake sequence disposed downstream of the transcription initiation sequence, wherein the cell uptake sequence is a cDNA of SEQ ID NO: 11, or a nucleotide sequence possessing at least 80% sequence identity thereto wherein a therapeutically effective amount of E6-associated protein (E6-AP) expressed by cells transfected with the UBE3A vector is secreted and taken up by cerebral cells with a deficiency in E6-AP expression.
A computerized method for assigning a probable taxonomic group to a query sequence of nucleic acid or amino acid, the method comprising: (a) determining a query vector corresponding to the query sequence, wherein the query vector indicates compositional characteristics of the query sequence; (b) computing distances between the query vector and a plurality of cluster centroids , wherein each of the plurality of cluster centroids is associated with one of a plurality of reference clusters created based on compositional characteristics of a plurality of reference sequences of nucleic acid or amino acid, characterized in that the method further comprises: (c) identifying, based on the computed distances, a predetermined number of closest cluster centroids from among the plurality of cluster centroids ; (d) generating a query signature corresponding to the query sequence based on the predetermined number of closest cluster centroids, wherein the query signature includes the predetermined number of closest cluster centroids ordered by their distances from the query vector; generating a lexically sorted list of the query signature and a plurality of reference signatures , wherein the lexically sorted list includes the query signature in the vicinity of compositionally and phylogenetically related reference signatures, and wherein each of the plurality of reference signatures is generated from a corresponding reference sequence from the plurality of reference sequences according to steps (a) to (d) and corresponds to one of a plurality of taxonomic groups; selecting a predetermined number of target reference signatures lying on either side of the query signature in the lexically sorted list, from amongst the plurality of reference signatures ; identifying, based on the one or more target reference signatures, the probable taxonomic group from amongst the plurality of taxonomic groups corresponding to the one or more target reference signatures; and assigning the probable taxonomic group to the query sequence. (a) determining a query vector corresponding to the query sequence, wherein the query vector indicates compositional characteristics of the query sequence; (b) computing distances between the query vector and a plurality of cluster centroids , wherein each of the plurality of cluster centroids is associated with one of a plurality of reference clusters created based on compositional characteristics of a plurality of reference sequences of nucleic acid or amino acid, characterized in that the method further comprises: (c) identifying, based on the computed distances, a predetermined number of closest cluster centroids from among the plurality of cluster centroids ; (d) generating a query signature corresponding to the query sequence based on the predetermined number of closest cluster centroids, wherein the query signature includes the predetermined number of closest cluster centroids ordered by their distances from the query vector;
Filter device comprising a filter housing and a filter element received therein, the element material of which extends between two end caps for the purpose of filtering a liquid, at least one end cap thereof being mounted on an element seat , the filter element being hingedly mounted on the element seat via one of its end caps by means of a bearing that provides more than one degree of freedom, characterised in that the bearing has a convexly extending bearing surface guided in a concavely extending bearing surface , and in that each bearing surface is a component part of a shell , at least one of which has a passage for liquid.
A computer-implemented method for configuring a theme color of a terminal device, wherein the method comprises: obtaining (S401) a tone type of a to-be-switched-to picture when it is detected that a terminal device switches a screen picture, wherein the obtaining of the tone type of the to-be-switched-to picture comprises collecting statistics on a luminance component and a purity component, in predetermined color space, of a pixel comprised in the picture and determining the tone type of the picture based on the luminance component and the purity component; determining (S402) cool and warm color system information of the picture; identifying (S403) arrangement and proportion information of a representative color system of the picture; and configuring (S404) a theme color of the terminal device based on the tone type, the cool and warm color system information, and the arrangement and proportion information of the representative color system. obtaining (S401) a tone type of a to-be-switched-to picture when it is detected that a terminal device switches a screen picture, wherein the obtaining of the tone type of the to-be-switched-to picture comprises collecting statistics on a luminance component and a purity component, in predetermined color space, of a pixel comprised in the picture and determining the tone type of the picture based on the luminance component and the purity component; determining (S402) cool and warm color system information of the picture; identifying (S403) arrangement and proportion information of a representative color system of the picture; and configuring (S404) a theme color of the terminal device based on the tone type, the cool and warm color system information, and the arrangement and proportion information of the representative color system.
System comprising a multimode optical fiber for continuous transmission of electromagnetic radiation at high power, said multimode optical fiber defining a fiber axis and comprising a core and a cladding surrounding the core , and wherein the multimode optical fiber is a multimode graded-index fiber, the refraction index profile in the fiber following the formula: n r = { n 1 1 − 2 r a g Δ 1 / 2 , r < a n 2 , r > a where Δ = n 1 2 − n 2 2 2 n 1 2 , r is the distance from the fiber axis, n(r) is the nominal refractive index as a function of distance from the fiber axis, n 1 is the nominal refractive index on the axis of the fiber , n 2 is the refractive index of the cladding , a is the core radius, and g is a parameter that defines the shape of the profile, characterized in that the core diameter 2a is comprised between 90 μm and 190 μm, the parameter g is comprised between 1.2 and 1.8, and the numerical aperture (NA) of the fiber , where NA = n 1 2 − n 2 2 , is comprised between 0.2 and 0.3, and in that the system comprises an electromagnetic radiation source configured to input continuous optical power into the multimode optical fiber , wherein the multimode optical fiber has a length above 500 meters and the input optical power is equal or greater than 1 W, wherein inputting said electromagnetic radiation includes inputting an electromagnetic radiation having an optical power below an input threshold value, wherein said input threshold value of said input optical power is equal to: P thr g = 10 log 3.6 π 10 13 a 2 A g V 2 / g + 2 + B g V 3 / 2 + C g V 6 2 , where V = ( 2aπ / λ ) NA , A g = 2 5 1 + 4 2 g 5 / 6 1 / 2 , B g = e 0.298 / g − 1 + 1.478 1 − e − 0.077 g , and C g = 3.76 + exp 4.19 / g 0.418 . r is the distance from the fiber axis, n(r) is the nominal refractive index as a function of distance from the fiber axis, n 1 is the nominal refractive index on the axis of the fiber , n 2 is the refractive index of the cladding , a is the core radius, and g is a parameter that defines the shape of the profile, the core diameter 2a is comprised between 90 μm and 190 μm, the parameter g is comprised between 1.2 and 1.8, and the numerical aperture (NA) of the fiber , where NA = n 1 2 − n 2 2 , is comprised between 0.2 and 0.3,
A brake valve for a pneumatic brake system for vehicles with at least one venting path for venting the brake valve along an outflow direction (R1), wherein the venting path comprises: a first volume , through which a flow can pass; a first compressed air passage , which pneumatically connects the first volume to a pressurized section of the brake valve ; a sealing device , which is designed to change at least between a normal state (Z1) and a sealed state (Z2); wherein, when the sealing device is in the normal state (Z1), the first compressed air passage can be flowed through both in the outflow direction (R1) and in an opposite inflow direction (R2), and wherein, when the sealing device is in the sealed state (Z2), the first compressed air passage can be flowed through only in the outflow direction (R1) but not in the inflow direction (R2), wherein the sealing device in the sealed state (Z2) fulfills the function of a check valve and forms a check valve in this state. a first volume , through which a flow can pass; a first compressed air passage , which pneumatically connects the first volume to a pressurized section of the brake valve ; a sealing device , which is designed to change at least between a normal state (Z1) and a sealed state (Z2); wherein, when the sealing device is in the normal state (Z1), the first compressed air passage can be flowed through both in the outflow direction (R1) and in an opposite inflow direction (R2), and wherein, when the sealing device is in the sealed state (Z2), the first compressed air passage can be flowed through only in the outflow direction (R1) but not in the inflow direction (R2), wherein the sealing device in the sealed state (Z2) fulfills the function of a check valve and forms a check valve in this state.
A method of performing an MRI without burning a patient with associated radio-frequency energy comprising: providing an MRI device having a patient barrel, the patient barrel defining a central longitudinal axis; positioning an infrared camera in a vertical plane intersecting the central longitudinal axis of the patient barrel, such that the infrared camera is vertically offset from the central longitudinal axis of the patient barrel and has a line of sight oriented downward at an angle relative to the central longitudinal axis of the patient barrel, the infrared camera having a field of view; applying RF energy to the patient in the patient barrel; monitoring, with the infrared camera, a mean surface temperature of the patient's body during the MRI within each of a plurality of regions of interest in an image frame; for each of the plurality of regions of interest, comparing a change in the mean surface temperature therein with a threshold value; causing an alert if the change in the mean surface temperature exceeds the threshold value for any one of the plurality of regions of interest; and altering the field of view of the infrared camera during the MRI to scan the surface temperature of the patient's body from head to toe. providing an MRI device having a patient barrel, the patient barrel defining a central longitudinal axis; positioning an infrared camera in a vertical plane intersecting the central longitudinal axis of the patient barrel, such that the infrared camera is vertically offset from the central longitudinal axis of the patient barrel and has a line of sight oriented downward at an angle relative to the central longitudinal axis of the patient barrel, the infrared camera having a field of view; applying RF energy to the patient in the patient barrel; monitoring, with the infrared camera, a mean surface temperature of the patient's body during the MRI within each of a plurality of regions of interest in an image frame; for each of the plurality of regions of interest, comparing a change in the mean surface temperature therein with a threshold value; causing an alert if the change in the mean surface temperature exceeds the threshold value for any one of the plurality of regions of interest; and altering the field of view of the infrared camera during the MRI to scan the surface temperature of the patient's body from head to toe.
A method of storing hydrogen gas, comprising: providing a polymer sponge, wherein said polymer sponge comprises a plurality of catalytic nanoparticles; providing a solution of reactants comprising water and an amine-borane compound or derivative thereof, in particular ammonia borane or a derivative thereof, catalysed by said nanoparticles to produce said gas; absorbing said solution into said polymer sponge such that said reactants react within said polymer sponge to produce said gas; wherein said gas is held within said polymer sponge; and wherein said polymer sponge comprises a thermally responsive polymer having a volume which reduces above the lower critical solution temperature, LCST, of the polymer, said that said gas held within said polymer is extractable by heating the temperature of said polymer sponge above the LCST; wherein said polymer comprises poly(N-isopropyl acrylamide); wherein said catalytic nanoparticles comprise complexes of a nanoparticle with a stabilising molecule, wherein said stabilising molecule interacts with said polymer and said nanoparticle to restrict agglomeration of said nanoparticles and stabilise a distribution of said nanoparticles during manufacture of said polymer; wherein said stabilising molecule provides a steric effect to further stabilise said nanoparticles, such that the nanoparticles are restricted from agglomerating with one another; wherein said stabilising molecule comprises cucurbit[n]uril; and wherein said nanoparticles comprise ruthenium nanoparticles. providing a polymer sponge, wherein said polymer sponge comprises a plurality of catalytic nanoparticles; providing a solution of reactants comprising water and an amine-borane compound or derivative thereof, in particular ammonia borane or a derivative thereof, catalysed by said nanoparticles to produce said gas; absorbing said solution into said polymer sponge such that said reactants react within said polymer sponge to produce said gas; wherein said gas is held within said polymer sponge; and wherein said polymer sponge comprises a thermally responsive polymer having a volume which reduces above the lower critical solution temperature, LCST, of the polymer, said that said gas held within said polymer is extractable by heating the temperature of said polymer sponge above the LCST; wherein said polymer comprises poly(N-isopropyl acrylamide); wherein said catalytic nanoparticles comprise complexes of a nanoparticle with a stabilising molecule, wherein said stabilising molecule interacts with said polymer and said nanoparticle to restrict agglomeration of said nanoparticles and stabilise a distribution of said nanoparticles during manufacture of said polymer; wherein said stabilising molecule provides a steric effect to further stabilise said nanoparticles, such that the nanoparticles are restricted from agglomerating with one another; wherein said stabilising molecule comprises cucurbit[n]uril; and wherein said nanoparticles comprise ruthenium nanoparticles.
An autonomous ground working vehicle comprising: a chassis ; wheels coupled to the chassis ; a motor housing coupled to the chassis , the motor housing defining a motor cavity extending in an axial direction, the motor housing comprising a first inner housing portion having a first helical thread about the motor cavity and a second inner housing portion having a second helical thread about the motor cavity that engages the first helical thread , wherein the first inner housing portion has a motor mounting surface and is axially translatable relative to the chassis and rotatably fixed relative to the chassis , and the second inner housing portion is rotatable relative to the chassis and axially fixed relative to the chassis , wherein the first inner housing portion comprises: an inner body extending from the motor mounting surface towards the second inner housing portion , wherein the inner body defines the first helical thread ; and an outer body extending axially from the motor mounting surface towards the second inner housing portion , wherein the outer body and the inner body define an annular gap that receives a portion of the second inner housing portion ; a tool motor fixed to the motor mounting surface , the tool motor having an output shaft extending in a first direction; and a tool fixed to the output shaft . a chassis ; wheels coupled to the chassis ; a motor housing coupled to the chassis , the motor housing defining a motor cavity extending in an axial direction, the motor housing comprising a first inner housing portion having a first helical thread about the motor cavity and a second inner housing portion having a second helical thread about the motor cavity that engages the first helical thread , wherein the first inner housing portion has a motor mounting surface and is axially translatable relative to the chassis and rotatably fixed relative to the chassis , and the second inner housing portion is rotatable relative to the chassis and axially fixed relative to the chassis , wherein the first inner housing portion comprises: an inner body extending from the motor mounting surface towards the second inner housing portion , wherein the inner body defines the first helical thread ; and an outer body extending axially from the motor mounting surface towards the second inner housing portion , wherein the outer body and the inner body define an annular gap that receives a portion of the second inner housing portion ; an inner body extending from the motor mounting surface towards the second inner housing portion , wherein the inner body defines the first helical thread ; and an outer body extending axially from the motor mounting surface towards the second inner housing portion , wherein the outer body and the inner body define an annular gap that receives a portion of the second inner housing portion ; a tool motor fixed to the motor mounting surface , the tool motor having an output shaft extending in a first direction; and a tool fixed to the output shaft .
Rubber compound for body ply skim comprising: - A mix of rubber consisting of (i) Epoxidized Natural Rubber acting as polymer base with a cross-linkable unsaturated chain; (ii) Natural Rubber acting as polymer base with a cross-linkable unsaturated chain; (iii) Polyepihalohydrin rubber, - a filler material, and - a vulcanization system; said compound being characterized in that it comprises: 70 to 90 phr of said Polyepihalohydrin rubber; 5 to 25 phr of said Epoxidized Natural Rubber (E-NR); and 5 to 25 phr of said Natural Rubber (NR); the phr ratio between E-NR and NR ranging from 0.2 to 5.0. - A mix of rubber consisting of (i) Epoxidized Natural Rubber acting as polymer base with a cross-linkable unsaturated chain; (ii) Natural Rubber acting as polymer base with a cross-linkable unsaturated chain; (iii) Polyepihalohydrin rubber, - a filler material, and - a vulcanization system;
Method for detecting the load (P VA ) weighing on a first vehicle axle with mechanical suspension for vehicles used for transportation comprising at least a second axle with pneumatic suspension provided with sensor for the detection of the load (P HA ) weighing on said second axle and a control unit and wherein the additional payload (P L ) on the vehicle is distributed among said axles , characterized in that it comprises: - a first step, carried only once on a single vehicle of a whole range of similar vehicles, for detecting the loads (P HA1 , P VA1 ) weighing on the axles , by weighing this latter on a weighing machine, with a first value (P L1 ) of the additional payload (P L ); - a second step, carried only once on a single vehicle of a whole range of similar vehicles, for detecting the loads (P HA2 , P VA2 ) weighing on the axles , by weighing this latter on a weighing machine, with a second value (P L2 ) of the additional payload (P L ); - a third calculation step for determining one parameter (tga) expressing a relation existing among the loads (P VA , P HA ) weighing on the axles ; and in that it comprises: - a further step for determining the value of the load (P VA ) weighing on said first axle with mechanical suspension by detecting the load value (P HA ) by means of said sensor and said control unit and multiplying said parameter (tga) by said detected loads value (P HA ), wherein said one parameter is a tangent of an angle (a) as angular coefficient of a linear interpolation calculation between at least two point (A, B) each of said points being representative of one of said two different values of the additional payload (P L1 , P L2 ). - a first step, carried only once on a single vehicle of a whole range of similar vehicles, for detecting the loads (P HA1 , P VA1 ) weighing on the axles , by weighing this latter on a weighing machine, with a first value (P L1 ) of the additional payload (P L ); - a second step, carried only once on a single vehicle of a whole range of similar vehicles, for detecting the loads (P HA2 , P VA2 ) weighing on the axles , by weighing this latter on a weighing machine, with a second value (P L2 ) of the additional payload (P L ); - a third calculation step for determining one parameter (tga) expressing a relation existing among the loads (P VA , P HA ) weighing on the axles ; - a further step for determining the value of the load (P VA ) weighing on said first axle with mechanical suspension by detecting the load value (P HA ) by means of said sensor and said control unit and multiplying said parameter (tga) by said detected loads value (P HA ), wherein said one parameter is a tangent of an angle (a) as angular coefficient of a linear interpolation calculation between at least two point (A, B) each of said points being representative of one of said two different values of the additional payload (P L1 , P L2 ).