mhurhangee/patent-ind-claim-en huggingface dataset:
Method for the product of a part in extrusion form constituted of a composite material with continuous-fiber reinforcement, in a thermoplastic matrix comprising at least two wings, of which the centers of the successive sections follow a curve and at least two faces extending in secant planes, said method comprising the steps consisting in: a. obtaining a planar blank , comprising a preconsolidated stack of plies, comprising fibers oriented at 0° with respect to the curvature of the blank, produced by automatically positioning so-called preimpregnated thermoplastic polymer fibers , according to curved trajectories comprising an operation consisting in: d. depositing via automatic fiber positioning, of the fibers oriented locally along the curvature of the blank by applying said fibers with a pressure and a temperature at the interface between said fibers and the preform constituted of a stack of fibrous plies also preimpregnated, greater by 5 °C to 10 °C than the melting temperature of the polymer, said fibers then being part of the preform, followed by a cooling of the fibers deposited by the means of cooling, with a deposition speed (V) that is selected in order to obtain a preconsolidation of the blank, i.e. with a rate of porosity less than 1% but without creating a continuous network of molecular chains in the thickness of the matrix; b. heating said blank to a temperature greater than or equal to the melting temperature of the polymer forming the matrix; c. hot-stamping the blank heated in this way and consolidating the part formed in this way between the punch and the stamping die. a. obtaining a planar blank , comprising a preconsolidated stack of plies, comprising fibers oriented at 0° with respect to the curvature of the blank, produced by automatically positioning so-called preimpregnated thermoplastic polymer fibers , according to curved trajectories comprising an operation consisting in: d. depositing via automatic fiber positioning, of the fibers oriented locally along the curvature of the blank by applying said fibers with a pressure and a temperature at the interface between said fibers and the preform constituted of a stack of fibrous plies also preimpregnated, greater by 5 °C to 10 °C than the melting temperature of the polymer, said fibers then being part of the preform, followed by a cooling of the fibers deposited by the means of cooling, with a deposition speed (V) that is selected in order to obtain a preconsolidation of the blank, i.e. with a rate of porosity less than 1% but without creating a continuous network of molecular chains in the thickness of the matrix; b. heating said blank to a temperature greater than or equal to the melting temperature of the polymer forming the matrix; c. hot-stamping the blank heated in this way and consolidating the part formed in this way between the punch and the stamping die.
A kit for use in treating a solid tumor associated with ED-B in a subject, wherein the solid tumor associated with ED-B has presence and/or expression of ED-B, the kit comprising a biologically inert drug and a biologically active drug, wherein - the biologically active drug comprises a targeting moiety and a biologically active moiety; - the biologically inert drug comprises a targeting moiety and a biologically inert moiety; optionally the biologically inert drug and the biologically active drug have the same targeting moiety, wherein the biologically inert drug and the biologically active drug are mixed and prepared into a single preparation or composition, or the biologically inert drug and the biologically active drug are prepared into separate preparations or compositions, respectively, wherein the targeting moiety is an antibody or a binding fragment thereof against the Extra-domain B (ED-B) of fibronectin, wherein the biologically active moiety is selected from TNF-alpha, IL-2 or IL-12, wherein the biologically inert moiety is selected from the group consisting of an antibody constant region, albumin, and a polyethylene glycol, and wherein the biologically inert drug substantially has no biological activity relative to a biologically active drug, which means that the biologically inert drug does not have the pharmaceutical effect as the biologically active drug, or at the same administered dosage, its pharmaceutical effect may be neglected compared with the biologically active drug. - the biologically active drug comprises a targeting moiety and a biologically active moiety; - the biologically inert drug comprises a targeting moiety and a biologically inert moiety; optionally the biologically inert drug and the biologically active drug have the same targeting moiety, wherein the biologically inert drug and the biologically active drug are mixed and prepared into a single preparation or composition, or the biologically inert drug and the biologically active drug are prepared into separate preparations or compositions, respectively, wherein the targeting moiety is an antibody or a binding fragment thereof against the Extra-domain B (ED-B) of fibronectin, wherein the biologically active moiety is selected from TNF-alpha, IL-2 or IL-12, wherein the biologically inert moiety is selected from the group consisting of an antibody constant region, albumin, and a polyethylene glycol, and wherein the biologically inert drug substantially has no biological activity relative to a biologically active drug, which means that the biologically inert drug does not have the pharmaceutical effect as the biologically active drug, or at the same administered dosage, its pharmaceutical effect may be neglected compared with the biologically active drug.
A reverse revolution preventing control device of an engine , comprising: an engine revolution cycle information acquisition means for acquiring a revolution cycle (T) of an engine ; an accelerator opening sensor for detecting an opening of an accelerator operated by a rider of a vehicle mounted with the engine ; and a throttle opening control means for controlling an opening of a throttle of the engine on the basis of the opening of the accelerator, the revolution cycle (T) of the engine , the output of a water temperature sensor for detecting the temperature of the cooling water of the engine , and the output of an atmospheric pressure sensor for detecting the atmospheric pressure, characterized by further comprising: an ignition control means which is configured to compare a specified reverse revolution threshold value (NT) determined from the opening of the accelerator with a present revolution cycle (T) of the engine , and to limit the ignition at a crank position before a compression top dead center when the present revolution cycle (T) of the engine is the reverse revolution threshold value (NT) or more by stopping ignition in that combustion cycle or causing ignition at the timing when the piston is positioned at the compression top dead center or later than that timing. an engine revolution cycle information acquisition means for acquiring a revolution cycle (T) of an engine ; an accelerator opening sensor for detecting an opening of an accelerator operated by a rider of a vehicle mounted with the engine ; and a throttle opening control means for controlling an opening of a throttle of the engine on the basis of the opening of the accelerator, the revolution cycle (T) of the engine , the output of a water temperature sensor for detecting the temperature of the cooling water of the engine , and the output of an atmospheric pressure sensor for detecting the atmospheric pressure, characterized by further comprising: an ignition control means which is configured to compare a specified reverse revolution threshold value (NT) determined from the opening of the accelerator with a present revolution cycle (T) of the engine , and to limit the ignition at a crank position before a compression top dead center when the present revolution cycle (T) of the engine is the reverse revolution threshold value (NT) or more by stopping ignition in that combustion cycle or causing ignition at the timing when the piston is positioned at the compression top dead center or later than that timing.
A method for processing an artificial turf, comprising: providing an artificial turf, the artificial turf including an infill; separating at least a portion of the infill from the artificial turf; downsizing the artificial turf into artificial turf fragments; and rotationally mixing and transporting the artificial turf fragments at a pressure less than a maximum predefined pressure to form a melt, wherein the maximum predefined pressure is between about 0.08 - 20 bar, characterized in that the method further comprises: pre-mixing the artificial turf fragments with the separated infill for forming a mixed material including up to 85 wt. % of the infill, and wherein rotationally mixing and transporting the artificial turf fragments comprises rotationally mixing and transporting the mixed material. providing an artificial turf, the artificial turf including an infill; separating at least a portion of the infill from the artificial turf; downsizing the artificial turf into artificial turf fragments; and rotationally mixing and transporting the artificial turf fragments at a pressure less than a maximum predefined pressure to form a melt, wherein the maximum predefined pressure is between about 0.08 - 20 bar, characterized in that the method further comprises: pre-mixing the artificial turf fragments with the separated infill for forming a mixed material including up to 85 wt. % of the infill, and wherein rotationally mixing and transporting the artificial turf fragments comprises rotationally mixing and transporting the mixed material.
An aluminum alloy brazing sheet for a heat exchanger, comprising a core material, a first filler material cladded on one surface of the core material and a second filler material cladded on the other surface of the core material, wherein: the core material consists of an Al alloy including 0.05-0.6% by mass of Si, 0.05-0.7% by mass of Fe and 0.6-2.0% by mass of Mn, the balance being Al and inevitable impurities, contents of Si, Fe and Mn satisfying a formula: Si + Fe ≦ Mn; and each of the first and second filler materials consists of an Al-Si based alloy including 4.5-13.0% by mass of Si and 0.05-0.8% by mass of Fe, the balance being Al and inevitable impurities, and wherein the brazing sheet is given a temper designation of HXY, X being 1 or 2 and Y being a natural number from 2 to 6, and has an electric resistivity at room temperature of 31-50nΩm in a portion formed of the core material; a dispersion ratio of second phase particles having a circle equivalent diameter of not more than 0.5μm is 5-50%·μm -1 in the portion formed of the core material, the dispersion ratio of the second phase particles being defined as f/r, wherein f (%) represents an area ratio of the second phase particles while r (μm) represents an average circle equivalent diameter of the second phase particles; the brazing sheet has an n-value of a work hardening exponent of not less than 0.010, where a nominal strain is within a range of 1%-2%; and the brazing sheet has a push-in depth of not less than 10mm when a penetration crack is generated in a punch stretch forming test using a round-head punch having a diameter of 50mm. the core material consists of an Al alloy including 0.05-0.6% by mass of Si, 0.05-0.7% by mass of Fe and 0.6-2.0% by mass of Mn, the balance being Al and inevitable impurities, contents of Si, Fe and Mn satisfying a formula: Si + Fe ≦ Mn; and each of the first and second filler materials consists of an Al-Si based alloy including 4.5-13.0% by mass of Si and 0.05-0.8% by mass of Fe, the balance being Al and inevitable impurities, and wherein the brazing sheet is given a temper designation of HXY, X being 1 or 2 and Y being a natural number from 2 to 6, and has an electric resistivity at room temperature of 31-50nΩm in a portion formed of the core material; a dispersion ratio of second phase particles having a circle equivalent diameter of not more than 0.5μm is 5-50%·μm -1 in the portion formed of the core material, the dispersion ratio of the second phase particles being defined as f/r, wherein f (%) represents an area ratio of the second phase particles while r (μm) represents an average circle equivalent diameter of the second phase particles; the brazing sheet has an n-value of a work hardening exponent of not less than 0.010, where a nominal strain is within a range of 1%-2%; and the brazing sheet has a push-in depth of not less than 10mm when a penetration crack is generated in a punch stretch forming test using a round-head punch having a diameter of 50mm.
An omni-directional acoustic deflector comprising: an acoustically reflective body having a substantially conical outer surface, and an inner surface opposite the outer surface, characterized in that the inner surface defines a region for contacting a first electronic component such that heat is transferred from the first electronic component to the outer surface of the acoustically reflective body. an acoustically reflective body having a substantially conical outer surface, and an inner surface opposite the outer surface, characterized in that the inner surface defines a region for contacting a first electronic component such that heat is transferred from the first electronic component to the outer surface of the acoustically reflective body.
A method for the diagnosis of non-alcoholic steatohepatitis (NASH), comprising the steps of: - measuring the level of blood, serum or plasma circulating hsa-miR-34, (in particular hsa-miR-34a and more particularly hsa-miR-34a-5p), - measuring the level of blood, serum or plasma circulating YKL-40, and - combining the results through a mathematical algorithm to obtain a NASH score wherein a NASH score is calculated according to the following logistic function: S ∼ e Y 1 + e Y wherein: Y = k + a * A + b * B wherein: S is the NASH score; A is the level of hsa-miR-34a (in particular hsa-miR-34a-5p) in Cq; B is the level of YKL-40 in pg/ml; k is a number comprised between -116.08 and 40.97, in particular 12.87; a is a number comprised between -0.82 and 0, in particular -0.42; b is a number comprised between 0 and 1.88E-05, in particular 8.160E-06; wherein a NASH score higher than a threshold value comprised between 0.1387 and 0.3481, in particular equal to 0.2187, is indicative of a severe NASH, or of a moderate or high NASH activity; and thus is indicative of a patient having a steatosis score ≥ 1, a hepatocyte ballooning score ≥ 1, a lobular inflammation score ≥ 1, a NAS ≥ 4 and a fibrosis stage ≥ 1. - measuring the level of blood, serum or plasma circulating hsa-miR-34, (in particular hsa-miR-34a and more particularly hsa-miR-34a-5p), - measuring the level of blood, serum or plasma circulating YKL-40, and - combining the results through a mathematical algorithm to obtain a NASH score S is the NASH score; A is the level of hsa-miR-34a (in particular hsa-miR-34a-5p) in Cq; B is the level of YKL-40 in pg/ml; k is a number comprised between -116.08 and 40.97, in particular 12.87; a is a number comprised between -0.82 and 0, in particular -0.42; b is a number comprised between 0 and 1.88E-05, in particular 8.160E-06;
A fusion protein comprising (i) a nuclease-inactive Cas9 domain; and (ii) a deaminase domain. (i) a nuclease-inactive Cas9 domain; and (ii) a deaminase domain.
A communication method, applied to a communications system supporting a first communications standard and a second communications standard, wherein the communications system comprises a base station supporting connectivity to a core network of the first communications standard and a core network of the second communications standard, and the method comprising: receiving, by a terminal , information broadcast by the base station in a cell served by the base station , wherein the information comprises a first area identity and a second area identity, wherein the first area identity is used to identify an area used for location management for a terminal in the first communications standard, and the second area identity is used to identify an area used for location management for a terminal in the second communications standard, and a format of the first area identity is different from a format of the second area identity; initiating, by the terminal a first area update to a core network of the second communications standard by sending a first area update request to the base station , in a case that the terminal enters the cell served by the base station from a cell served by another base station of the second communications standard and when the second area identity in the information received by the terminal does not belong to a current area list of the terminal , wherein the current area list is allocated by the core network of the second communications standard before the terminal enters the cell served by the base station and does not include the first area identity. receiving, by a terminal , information broadcast by the base station in a cell served by the base station , wherein the information comprises a first area identity and a second area identity, wherein the first area identity is used to identify an area used for location management for a terminal in the first communications standard, and the second area identity is used to identify an area used for location management for a terminal in the second communications standard, and a format of the first area identity is different from a format of the second area identity; initiating, by the terminal a first area update to a core network of the second communications standard by sending a first area update request to the base station , in a case that the terminal enters the cell served by the base station from a cell served by another base station of the second communications standard and when the second area identity in the information received by the terminal does not belong to a current area list of the terminal , wherein the current area list is allocated by the core network of the second communications standard before the terminal enters the cell served by the base station and does not include the first area identity.
A low profile dump trailer for use with a tractor unit having at least one rear wheel and axle assembly with left and right wheels , comprising a goose neck adapted for removable coupling to the tractor unit and a dropped frame joined to the goose neck and extending rearwardly of the goose neck , the dropped frame having a front and a rear and a top and a bottom, characterized in that the low profile dump trailer further comprises an open box bed joined to the top of the dropped frame and extending at least partially below the goose neck for receiving cargo and having a front and having a rear opening for permitting discharge of the cargo from the open bed , the open box bed having a rectangular cross section or an open half cylinder with a semi-circular cross section and having a top height above ground of between 1.52-1.83 m (five and six feet), and a plurality of trailer wheel and axle assemblies joined to the bottom of the rear of the dropped frame , each of the plurality of trailer wheel and axle assemblies having left and right wheels suitable for highway travel, each of the left and right wheels of the plurality of trailer wheel and axle assemblies being disposed entirely underneath the open bed .
A method for operating a crushing assembly with blades which are rotatable about an axle and a stationary counter cutter which is disposed parallel to the axle by means of an operating device , wherein a state of wear of the blades and a spacing of the blades from the counter cutter are detected and displayed by the operating device , wherein the state of wear and the spacing are displayed in an online display, characterized in that a state of wear and/or a spacing which exceeds a threshold which is common to all of the blades initiates a maintenance requirement signal on the online display, and wherein the threshold can be adjusted by means of a virtual adjusting actuator, preferably a virtual thumb wheel, which is depicted on the online display, wherein, upon touching the display of the operating device in the region where the state of wear and the spacing of the blades from the counter cutter are depicted, the operating device opens a secondary screen in which the state of wear of each individual blade is graphically depicted. the threshold can be adjusted by means of a virtual adjusting actuator, preferably a virtual thumb wheel, which is depicted on the online display, wherein, upon touching the display of the operating device in the region where the state of wear and the spacing of the blades from the counter cutter are depicted, the operating device opens a secondary screen in which the state of wear of each individual blade is graphically depicted.
Appliance , which comprises an appliance interface for connecting a power cable , and comprises a control unit ; wherein - the appliance interface is designed to form, with an appliance-side interface unit of the power cable , a plug-in connection; - the appliance interface comprises at least one power contact part , which is designed to form, with a power contact part of the appliance-side interface unit , a power connection , in order to supply the appliance with electrical energy from an electrical supply grid; - the appliance interface comprises a first thermoelectric element ; characterised in that the appliance interface is designed to make contact, when the power connection exists, with a second thermoelectric element of the appliance-side interface unit , which differs from the first thermoelectric element , at a direct junction between the first thermoelectric element and the second thermoelectric element, so that the first thermoelectric element and the second thermoelectric element form a thermocouple for the power connection ; - the first thermoelectric element is coupled to a first measurement input of the control unit ; - the appliance interface comprises a measurement contact part, which is designed to form a measurement connection , between the second thermoelectric element and a second measurement input of the control unit , with a measurement contact part of the appliance-side interface unit ; and - the control unit is designed to determine measurement data relating to a measurement voltage between the first measurement input and the second measurement input. - the appliance interface is designed to form, with an appliance-side interface unit of the power cable , a plug-in connection; - the appliance interface comprises at least one power contact part , which is designed to form, with a power contact part of the appliance-side interface unit , a power connection , in order to supply the appliance with electrical energy from an electrical supply grid; - the appliance interface comprises a first thermoelectric element ; characterised in that the appliance interface is designed to make contact, when the power connection exists, with a second thermoelectric element of the appliance-side interface unit , which differs from the first thermoelectric element , at a direct junction between the first thermoelectric element and the second thermoelectric element, so that the first thermoelectric element and the second thermoelectric element form a thermocouple for the power connection ; - the first thermoelectric element is coupled to a first measurement input of the control unit ; - the appliance interface comprises a measurement contact part, which is designed to form a measurement connection , between the second thermoelectric element and a second measurement input of the control unit , with a measurement contact part of the appliance-side interface unit ; and - the control unit is designed to determine measurement data relating to a measurement voltage between the first measurement input and the second measurement input.