mhurhangee/patent-ind-claim-en huggingface dataset:
A method for a network node for operating in an unlicensed frequency band, the method comprising: modifying (S100) at least one function of at least one carrier in a frequency band edge of the unlicensed frequency band, the frequency band edge being located, in a frequency domain, in a non-transmission portion of a spectrum mask that is configured to reduce leakage into an adjacent frequency band; and performing (S102) a communication function using the at least one carrier having the modified at least one function; characterized in that the at least one carrier having the modified at least one function includes a master carrier for performing at least one listen before talk, LBT, function related to determining whether a transmission is present on the at least one carrier before the at least one carrier is used for performing the communication function. modifying (S100) at least one function of at least one carrier in a frequency band edge of the unlicensed frequency band, the frequency band edge being located, in a frequency domain, in a non-transmission portion of a spectrum mask that is configured to reduce leakage into an adjacent frequency band; and performing (S102) a communication function using the at least one carrier having the modified at least one function; characterized in that the at least one carrier having the modified at least one function includes a master carrier for performing at least one listen before talk, LBT, function related to determining whether a transmission is present on the at least one carrier before the at least one carrier is used for performing the communication function.
Unit comprising an impaction device and a stem, said device being intended to impart a blow to the stem, the stem itself being coupled to an element forming an insert intended to be inserted into a receiving element, in particular a ceramic insert in a cup of a cotyloid cavity of a hip; the impaction device comprising: - an element forming a barrel defining a channel or an internal chamber that has an opening via which at least part of the stem, in particular a proximal end segment of the stem, is inserted; - means of applying a blow intended to apply to the part of the stem introduced into the chamber a pre-determined blow force; and - means for triggering the blow application means, characterized in that pre-stressing means are provided which enable the user to press the device against the stem before triggering the triggering means and so the action of the hammer on the stem, the arrangement being such that in at least a first so-called blow application position, the proximal end segment of the stem is located at least partially within the channel, and in a second position, after application of the blow, the proximal end segment of the stem is located outside of the channel , wherein the pre-stressing means comprise a runner that is fitted so as to slide relative to the element forming the barrel, and means are provided that form a stop originating from the stem intended to strike against the edge of the distal opening of the runner. - an element forming a barrel defining a channel or an internal chamber that has an opening via which at least part of the stem, in particular a proximal end segment of the stem, is inserted; - means of applying a blow intended to apply to the part of the stem introduced into the chamber a pre-determined blow force; and - means for triggering the blow application means,
A process for the preparation of a crystalline compound having the formula: comprising: (a) adding concentrated sulfuric acid to a solution of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide in EtOH to form the hydrogen sulfate salt of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide; (b) adding heptane to the solution in Step (a) to form a slurry; (c) filtering the slurry to isolate (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate; (d) mixing said (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate with a 5:95 w/w solution of water/2-butanone; (e) heating the mixture from step (d) at about 65-70 °C with stirring until the weight percent of ethanol is about 0.5% to form a slurry of the crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate; and (f) isolating the crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate by filtration. (a) adding concentrated sulfuric acid to a solution of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide in EtOH to form the hydrogen sulfate salt of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide; (b) adding heptane to the solution in Step (a) to form a slurry; (c) filtering the slurry to isolate (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate; (d) mixing said (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate with a 5:95 w/w solution of water/2-butanone; (e) heating the mixture from step (d) at about 65-70 °C with stirring until the weight percent of ethanol is about 0.5% to form a slurry of the crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate; and (f) isolating the crystalline form of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide hydrogen sulfate by filtration.
A memory controller configured to be connected to a far memory control logic via a memory channel comprising ECC signal lines, the far memory control logic comprising a far memory write buffer , wherein the memory controller is further configured to: maintain a write buffer credit count, decrement the write buffer credit count when a far memory write request is determined to be presented to the far memory write buffer , decrement the write buffer credit count when a far memory write request is issued from the far memory write buffer , and receive, from the far memory control logic , each time the far memory control logic performs a read of a far memory, information on the issuance of a far memory write request from the far memory write buffer to the far memory , wherein the information is piggybacked by the far memory control logic with a far memory read request response, wherein said information is received by the memory controller on the ECC signal lines of the memory channel, wherein said information includes a write buffer issue count indicating how many write requests have issued since a last far memory read request response. maintain a write buffer credit count, decrement the write buffer credit count when a far memory write request is determined to be presented to the far memory write buffer , decrement the write buffer credit count when a far memory write request is issued from the far memory write buffer , and receive, from the far memory control logic , each time the far memory control logic performs a read of a far memory, information on the issuance of a far memory write request from the far memory write buffer to the far memory , wherein the information is piggybacked by the far memory control logic with a far memory read request response, wherein said information is received by the memory controller on the ECC signal lines of the memory channel, wherein said information includes a write buffer issue count indicating how many write requests have issued since a last far memory read request response.
2-aminothiazole derivatives, represented by formula (I) Wherein, the derivatives are selected from the group consisting of the following compounds: 2-(4-(4-methoxyphenyl) piperazin-1-yl)-N-(4-phenyl-thiazol-2-yl) butyramide, 3-(4-benzyl-piperazin-1-y1)-N-(4-phenyl-thiazol-2-yl)-propionamide, and 3-(N, N-pyridylmethyl-ethyl amine)-N-(4-phenyl-thiazole-5-methyl-2-yl)-propionamide. 2-(4-(4-methoxyphenyl) piperazin-1-yl)-N-(4-phenyl-thiazol-2-yl) butyramide, 3-(4-benzyl-piperazin-1-y1)-N-(4-phenyl-thiazol-2-yl)-propionamide, and 3-(N, N-pyridylmethyl-ethyl amine)-N-(4-phenyl-thiazole-5-methyl-2-yl)-propionamide.
An oven for blowing or stretch-blowing preforms (P) to provide containers (C) with oval section, comprising a path for the preforms (P), transfer means of the preforms (P) from a transport system upstream of the oven and transfer means of the heated preforms (P) from the oven to transport means downstream, wherein a plurality of mandrels is slidingly carried along the path , the mandrels configured so as to temporarily engage with the preforms (P) to conduct them along the path , the oven comprising at least one first heating module and at least one second heating module , the oven comprises means for rotating said preforms (P) by 180°, said means being in median position of said at least one second heating module , wherein the mandrel comprises a body inside of which a gripping finger for a preform (P) is slidingly inserted, which finger extends along a vertical axis (X), and wherein an orientation member extends from the body along said axis (X), in direction opposite to the gripping finger , said orientation member being integral in rotation with said gripping finger and wherein the orientation member comprises a rod having a first end, which is integral in rotation with the gripping finger of the mandrel , and a second end to which a toothed wheel is fastened, and wherein a positioning bearing configured to slide in a slot of a sliding guide is pivotally supported on a surface of the toothed wheel facing upwards, the positioning bearing having a rotation axis (X"), a diameter (d) and a radius (r), characterised in that a toothed sector is arranged on the rod , in intermediate position between the toothed wheel and the first end of the rod , the toothed sector being arranged in fixed and predetermined position with respect to the positioning bearing . wherein the mandrel comprises a body inside of which a gripping finger for a preform (P) is slidingly inserted, which finger extends along a vertical axis (X), and wherein an orientation member extends from the body along said axis (X), in direction opposite to the gripping finger , said orientation member being integral in rotation with said gripping finger and wherein the orientation member comprises a rod having a first end, which is integral in rotation with the gripping finger of the mandrel , and a second end to which a toothed wheel is fastened, and wherein a positioning bearing configured to slide in a slot of a sliding guide is pivotally supported on a surface of the toothed wheel facing upwards, the positioning bearing having a rotation axis (X"), a diameter (d) and a radius (r), characterised in that a toothed sector is arranged on the rod , in intermediate position between the toothed wheel and the first end of the rod , the toothed sector being arranged in fixed and predetermined position with respect to the positioning bearing .
A method of controlling a heater arrangement in an apparatus arranged to heat smokable material to volatise at least one component of said smokable material, the method comprising: implementing a heater control loop to control a heating element of the heater arrangement to heat a zone of the apparatus to a target temperature, wherein the control loop comprises, in one or more successive control periods, performing the steps of: determining a current temperature in the zone ; determining a current rate of change of temperature in the zone ; and determining a current remaining on time for the heating element of the heating arrangement to heat the zone to the target temperature based on the current rate of change of temperature, the target temperature and the current temperature of the zone . determining a current temperature in the zone ; determining a current rate of change of temperature in the zone ; and determining a current remaining on time for the heating element of the heating arrangement to heat the zone to the target temperature based on the current rate of change of temperature, the target temperature and the current temperature of the zone .
A positive active material for a lithium secondary battery comprising a lithium transition metal composite oxide, wherein the lithium transition metal composite oxide has an α-NaFeO 2 type crystal structure, and is represented by formula Li w Ni x Co y Mn z O 1+w with w > 1, x + y + z = 1 0.315 < x < 0.35 , 0 ≤ y ≤ 0.02 , 0.655 < z < 0.675 , and and 0.475 < w − 2 x − y / w < 0.510 . has an α-NaFeO 2 type crystal structure, and is represented by formula Li w Ni x Co y Mn z O 1+w with w > 1, x + y + z = 1 0.315 < x < 0.35 , 0 ≤ y ≤ 0.02 , 0.655 < z < 0.675 , and and 0.475 < w − 2 x − y / w < 0.510 .
A micro-optic security device , comprising: a planar array of micro-optic focusing elements ; and a first arrangement of image icons , each image icon of the first arrangement of image icons comprising a region of light-cured material, wherein the first arrangement of image icons is visible through the planar array of micro-optic focusing elements across a first predetermined range of viewing angles relative to the micro-optic security device, and wherein the first arrangement of image icons is not visible through the planar array of micro-optic focusing elements across a second predetermined range of viewing angles relative to the micro-optic security device; characterized in that image icons of the first arrangement of image icons comprise regions of light-cured material with focally tapered sidewall profiles. a planar array of micro-optic focusing elements ; and a first arrangement of image icons , each image icon of the first arrangement of image icons comprising a region of light-cured material, wherein the first arrangement of image icons is visible through the planar array of micro-optic focusing elements across a first predetermined range of viewing angles relative to the micro-optic security device, and wherein the first arrangement of image icons is not visible through the planar array of micro-optic focusing elements across a second predetermined range of viewing angles relative to the micro-optic security device; characterized in that image icons of the first arrangement of image icons comprise regions of light-cured material with focally tapered sidewall profiles.
A composition for use in treating a renal disease or disorder in a subject, the use comprising administering to the subject the composition, wherein the composition comprises at least one agent, wherein the at least one agent is at least one selected from the group consisting of a renalase polypeptide fragment consisting of the amino acid sequence of SEQ ID NO: 3, and a renalase polypeptide fragment consisting of the amino acid sequence of SEQ ID NO: 4.
An in vitro method for designing a customized therapy for a subject having breast cancer which comprises: i) quantifying the c-MAF gene expression level, copy number, amplification, or gain in a sample of said subject and ii) comparing the expression level, copy number, amplification, or gain obtained in i) with a reference value, wherein if the expression level, copy number, amplification, or gain is not increased with respect to said reference value, then said subject is susceptible to receive a therapy selected from the group consisting of: clodronate, ibandronate, and zoledronic acid. i) quantifying the c-MAF gene expression level, copy number, amplification, or gain in a sample of said subject and ii) comparing the expression level, copy number, amplification, or gain obtained in i) with a reference value,
A lens system for use as either an intra-ocular lens or as an insert into the corneal tissue of a natural eye to replace one or more optical functions of the natural eye, the lens system comprising: a base lens element having a base refractive power and formed of a soft acrylic; an electro-active lens element , encapsulated within the base lens element, having an electrically controllable focus; and an annular charge storage capacitor arranged around a perimeter of the electro-active lens element or a rechargeable battery ring , said annular charge storage capacitor or rechargeable battery ring being configured to power the electro-active lens element and to be charged inductively via an external induction coil . a base lens element having a base refractive power and formed of a soft acrylic; an electro-active lens element , encapsulated within the base lens element, having an electrically controllable focus; and an annular charge storage capacitor arranged around a perimeter of the electro-active lens element or a rechargeable battery ring , said annular charge storage capacitor or rechargeable battery ring being configured to power the electro-active lens element and to be charged inductively via an external induction coil .
A wearable pack, comprising: a body defining a volume for the containment of articles, the body generally having a height, a width, and a depth, and at least one body strap coupled to the body; and an adjustable tensile member and an adjustment mechanism with a cover plate, wherein the body strap comprises a core defining an aperture to receive at least a portion of the adjustment mechanism, wherein the adjustment mechanism defines a fastener member having an outwardly extending flange so urging against a first side of the core as to align the fastener member with the aperture extending through the core, and wherein the fastener member defines first and second apertures and a cross-member positioned therebetween, wherein the adjustable tensile member extends through the first aperture in a direction extending from a first side of the body strap to a second side of the body strap, over the cross-member and through the second aperture in a direction extending from the second side of the body strap to the first side of the body strap to slidably couple the adjustable tensile member and the adjustment mechanism with each other, and wherein the cover plate is positioned adjacent the second side of the body strap in a mating engagement with the fastener member to obscure a segment of the adjustable tensile member. a body defining a volume for the containment of articles, the body generally having a height, a width, and a depth, and at least one body strap coupled to the body; and an adjustable tensile member and an adjustment mechanism with a cover plate, wherein the body strap comprises a core defining an aperture to receive at least a portion of the adjustment mechanism, wherein the adjustment mechanism defines a fastener member having an outwardly extending flange so urging against a first side of the core as to align the fastener member with the aperture extending through the core, and wherein the fastener member defines first and second apertures and a cross-member positioned therebetween, wherein the adjustable tensile member extends through the first aperture in a direction extending from a first side of the body strap to a second side of the body strap, over the cross-member and through the second aperture in a direction extending from the second side of the body strap to the first side of the body strap to slidably couple the adjustable tensile member and the adjustment mechanism with each other, and wherein the cover plate is positioned adjacent the second side of the body strap in a mating engagement with the fastener member to obscure a segment of the adjustable tensile member.
A temperature control assembly, comprising: a cold plate having a first contact surface and a second contact surface opposite the first contact surface, wherein the cold plate is composed of a thermally conductive material; a channel formed in the cold plate and enclosed by the cold plate between the first contact surface and the second contact surface of the cold plate; an inlet formed in the channel for providing inflow of a liquid to the channel; an outlet formed in the channel for providing outflow of the liquid from the channel; at least one aperture formed in the cold plate, wherein the aperture is sized to receive an electrical connection between a printed circuit board when the printed circuit board is coupled to the first contact surface of the cold plate and a photodetector assembly when the photodetector assembly is coupled to the second contact surface of the cold plate; and characterized in that the temperature control assembly further comprises: a thermally conductive pad coupled to the second contact surface; a heating element coupled to the thermally conductive pad; and a temperature sensor that measures a temperature of electrical components mounted to a printed circuit board when the printed circuit board is coupled to one of the first contact surface or the second contact surface, and wherein the temperature sensor provides the measured temperature to a controller in order to control a power supplied to the heating element. a cold plate having a first contact surface and a second contact surface opposite the first contact surface, wherein the cold plate is composed of a thermally conductive material; a channel formed in the cold plate and enclosed by the cold plate between the first contact surface and the second contact surface of the cold plate; an inlet formed in the channel for providing inflow of a liquid to the channel; an outlet formed in the channel for providing outflow of the liquid from the channel; at least one aperture formed in the cold plate, wherein the aperture is sized to receive an electrical connection between a printed circuit board when the printed circuit board is coupled to the first contact surface of the cold plate and a photodetector assembly when the photodetector assembly is coupled to the second contact surface of the cold plate; and a thermally conductive pad coupled to the second contact surface; a heating element coupled to the thermally conductive pad; and a temperature sensor that measures a temperature of electrical components mounted to a printed circuit board when the printed circuit board is coupled to one of the first contact surface or the second contact surface, and wherein the temperature sensor provides the measured temperature to a controller in order to control a power supplied to the heating element.