An Optical Coherence Tomography, OCT, imaging system , comprising: an OCT light source operable to emit an OCT light beam , a sample arm waveguide (108; 508; 608; 708) and a reference arm waveguide (106; 506; 606; 706), and a beam splitter operable to split the OCT light beam into a sample beam delivered to the sample arm waveguide (108; 508; 608; 708), and a reference beam delivered to the reference arm waveguide (106; 506; 606; 706), characterized by a cladding (523; 623; 729) coupling the sample arm waveguide (108; 508; 608; 708) and the reference arm waveguide (106; 506; 606; 706) together, wherein the cladding (523; 623; 729) is conformally disposed over the sample arm waveguide (108; 508; 608; 708) and the reference arm waveguide (106; 506; 606; 706), for improving a calibration of a generated OCT image by minimizing axial movement of the sample arm waveguide (108; 508; 608; 708) and the reference arm waveguide (106; 506; 606; 706) relative to one another, wherein the reference arm waveguide (106; 506; 606) comprises a first core (521; 621) surrounded by the cladding (523; 623), and the sample arm waveguide (108; 508; 608) comprises a second core (525; 625) surrounded by the cladding (523; 623), and wherein a buffer is disposed over the cladding (523; 623), or wherein the reference arm waveguide comprises a first core surrounded by a first section of a first additional cladding concentrically disposed over the first core , and the sample arm waveguide comprises a second core , separate from the first core , wherein the second core is surrounded by a second section of a second additional cladding concentrically disposed over the second core , and wherein a buffer serving as the cladding is disposed over the first section of the first additional cladding and the second section of the second additional cladding , and wherein the reference arm waveguide (106; 506; 606; 706) and the sample arm waveguide (108; 508; 608; 708) are glass, and wherein the buffer (529; 629; 729) is a polymer. an OCT light source operable to emit an OCT light beam , a sample arm waveguide (108; 508; 608; 708) and a reference arm waveguide (106; 506; 606; 706), and a beam splitter operable to split the OCT light beam into a sample beam delivered to the sample arm waveguide (108; 508; 608; 708), and a reference beam delivered to the reference arm waveguide (106; 506; 606; 706), characterized by a cladding (523; 623; 729) coupling the sample arm waveguide (108; 508; 608; 708) and the reference arm waveguide (106; 506; 606; 706) together, wherein the cladding (523; 623; 729) is conformally disposed over the sample arm waveguide (108; 508; 608; 708) and the reference arm waveguide (106; 506; 606; 706), for improving a calibration of a generated OCT image by minimizing axial movement of the sample arm waveguide (108; 508; 608; 708) and the reference arm waveguide (106; 506; 606; 706) relative to one another, wherein the reference arm waveguide (106; 506; 606) comprises a first core (521; 621) surrounded by the cladding (523; 623), and the sample arm waveguide (108; 508; 608) comprises a second core (525; 625) surrounded by the cladding (523; 623), and wherein a buffer is disposed over the cladding (523; 623), or wherein the reference arm waveguide comprises a first core surrounded by a first section of a first additional cladding concentrically disposed over the first core , and the sample arm waveguide comprises a second core , separate from the first core , wherein the second core is surrounded by a second section of a second additional cladding concentrically disposed over the second core , and wherein a buffer serving as the cladding is disposed over the first section of the first additional cladding and the second section of the second additional cladding , and wherein the reference arm waveguide (106; 506; 606; 706) and the sample arm waveguide (108; 508; 608; 708) are glass, and wherein the buffer (529; 629; 729) is a polymer. <EOS>