mhurhangee/patent-ind-claim-en huggingface dataset:
A method of large-scale transfection of cells, comprising: contacting the cells with a plurality of nanoparticles to thereby produce nanoparticle-tagged target cells, wherein the nanoparticles have an affinity moiety that binds specifically to a marker on the target cells, and wherein the cells are disposed in a medium; introducing a cargo material into the medium, wherein the cargo material is at least one of a stimulant of an immune response and a regulatory element of an immune response; and exciting the nanoparticles on the nanoparticle-tagged target cells in the medium with an electro-magnetic stimulus at an energy of at least 1 mJ to cause transient poration of the nanoparticle-tagged target cell and uptake of the cargo material into the nanoparticle-tagged target cell; wherein the step of exciting is performed at a cell density of at least 1×10 4 cells/cm 2 in static medium or at a cell density of at least 1×10 6 cells/hr in moving medium. contacting the cells with a plurality of nanoparticles to thereby produce nanoparticle-tagged target cells, wherein the nanoparticles have an affinity moiety that binds specifically to a marker on the target cells, and wherein the cells are disposed in a medium; introducing a cargo material into the medium, wherein the cargo material is at least one of a stimulant of an immune response and a regulatory element of an immune response; and exciting the nanoparticles on the nanoparticle-tagged target cells in the medium with an electro-magnetic stimulus at an energy of at least 1 mJ to cause transient poration of the nanoparticle-tagged target cell and uptake of the cargo material into the nanoparticle-tagged target cell; wherein the step of exciting is performed at a cell density of at least 1×10 4 cells/cm 2 in static medium or at a cell density of at least 1×10 6 cells/hr in moving medium.
An underpants-shaped absorbent article having an up-down direction, a left-right direction, and a front-rear direction that intersect each other, the underpants-shaped absorbent article comprising: an absorbent main body ; and a first waist portion that is joined to the absorbent main body and that includes a stretchy sheet having stretchability in the left-right direction, the stretchy sheet having a lower end , the lower end being located at a position separated upward in the up-down direction by a predetermined distance from an upper end of the absorbent main body , wherein the first waist portion includes a plurality of elastic members having stretchability in the left-right direction, and a left-right-direction mean stress (σ BR ) in an up-down-direction region (BR) of the first waist portion that is between the lower end of the stretchy sheet and an elastic member located at an uppermost position among the plurality of elastic members is smaller than a left-right-direction mean stress (σ UR ) in an up-down-direction region (UR) of the first waist portion in which the stretchy sheet is arranged, and wherein an up-down-direction length of the up-down-direction region (UR) in which the stretchy sheet is arranged is longer than an up-down-direction length between the lower end of the stretchy sheet and the elastic member located uppermost. an absorbent main body ; and a first waist portion that is joined to the absorbent main body and that includes a stretchy sheet having stretchability in the left-right direction, the stretchy sheet having a lower end , the lower end being located at a position separated upward in the up-down direction by a predetermined distance from an upper end of the absorbent main body , wherein the stretchy sheet having a lower end , the lower end being located at a position separated upward in the up-down direction by a predetermined distance from an upper end of the absorbent main body , wherein the first waist portion includes a plurality of elastic members having stretchability in the left-right direction, and a left-right-direction mean stress (σ BR ) in an up-down-direction region (BR) of the first waist portion that is between the lower end of the stretchy sheet and an elastic member located at an uppermost position among the plurality of elastic members is smaller than a left-right-direction mean stress (σ UR ) in an up-down-direction region (UR) of the first waist portion in which the stretchy sheet is arranged, and wherein an up-down-direction length of the up-down-direction region (UR) in which the stretchy sheet is arranged is longer than an up-down-direction length between the lower end of the stretchy sheet and the elastic member located uppermost.
An apparatus comprising: a camera to capture an image of a shell of a live crustacean; an image processor , operatively coupled to the camera, to process the captured image to determine a physical attribute of the shell of the live crustacean, the image processor comprising a pattern detector to detect from the captured image a characteristic of a pattern on the shell indicative of moult stage of the live crustacean. a camera to capture an image of a shell of a live crustacean; an image processor , operatively coupled to the camera, to process the captured image to determine a physical attribute of the shell of the live crustacean, the image processor comprising a pattern detector to detect from the captured image a characteristic of a pattern on the shell indicative of moult stage of the live crustacean.
A method for providing film grain information, comprising the steps of: characterizing a video stream prior to encoding to provide information indicative of film grain within the video stream, the film grain information including at least one parameter specifying an attribute of the film grain in the video stream; and encoding the film grain information for subsequent transmission together with the encoded video stream, wherein the film grain information includes a set of parameters, each specifying a different film grain attribute, characterised in that the set of parameters includes at least one parameter defining a spatial correlation of a perceived pattern of the film grain according to a second-order auto regression model. characterizing a video stream prior to encoding to provide information indicative of film grain within the video stream, the film grain information including at least one parameter specifying an attribute of the film grain in the video stream; and encoding the film grain information for subsequent transmission together with the encoded video stream, wherein the film grain information includes a set of parameters, each specifying a different film grain attribute, characterised in that the set of parameters includes at least one parameter defining a spatial correlation of a perceived pattern of the film grain according to a second-order auto regression model.
Device for dissociating an aqueous phase to produce gaseous hydrogen, said device comprising: - a first zone comprising said aqueous phase, - a means of capturing electrons, - a means of reducing protons, and - an electrical energy source arranged to apply an electric energy potential between said electron capture means and said proton reduction means to produce, via an oxidation reaction of said aqueous phase at said electron capture means, gaseous oxygen, electrons and protons, said proton reduction means being arranged to carry out a reduction reaction of said protons by said electrons in order to produce gaseous hydrogen and being a proton exchange interface constituting a separation between said first zone comprising said aqueous phase and a second non-aqueous zone, said separation being a separation not allowing said aqueous phase to pass but allowing protons to pass to said second non-aqueous zone, said proton exchange interface exhibiting: - a front face located in said first zone comprising said aqueous phase and facing towards said electron capture means, and - a back face located in said second non-aqueous zone and comprising at least one catalyst and/or at least one catalytic system, said device being characterised in that said at least one catalyst and/or said at least one catalytic system comprises enzymes of the hydrogenase type. - a first zone comprising said aqueous phase, - a means of capturing electrons, - a means of reducing protons, and - an electrical energy source arranged to apply an electric energy potential between said electron capture means and said proton reduction means to produce, via an oxidation reaction of said aqueous phase at said electron capture means, gaseous oxygen, electrons and protons, - a front face located in said first zone comprising said aqueous phase and facing towards said electron capture means, and - a back face located in said second non-aqueous zone and comprising at least one catalyst and/or at least one catalytic system,
A motor vehicle power steering system comprising a steering handle having at least one handle sensor , an electronically controlled steering actuator having an electric motor (M) for providing an actuating torque, a mechanical power transmission for transmitting the actuating torque to steered wheels , and a position sensor for detecting a wheel position (dX) of the steered wheels , wherein there is further provided a monitoring device which is configured to relate the wheel position (dX) detected by the position sensor to at least one input parameter (β, Rp, T) of the mechanical power transmission given by the electric motor (M) in order to monitor the functioning of the mechanical power transmission , characterized in that the motor vehicle power steering system is designed in the form of a steer-by-wire steering system, the handle sensor is configured for detecting a handle position (α) of the steering handle and the electric motor (M) is configured for providing the actuating torque in dependence on the detected handle position (α), wherein the detection of the wheel position (dX) of the steered wheels takes place directly at the wheels or indirectly by arranging the position sensor on a rack of the steering system .
Microfluidic chip capable of carrying out manipulations of cells and/or structuring and/or culturing thereof, comprising: - a block made from biocompatible material, - a passage channel made in the block for the passage of cells bathed in a liquid, - a resonant cavity made in the block , connected to the passage channel, - an acoustic wave generator capable of forming at least one cell aggregate in acoustic levitation in the resonant cavity, - at least one optical emitter capable of illuminating cells in the resonant cavity through at least one wall of the resonant cavity and simultaneous with the generation of acoustic waves in such a way as to structure said at least one aggregate by means of the technique of optical exclusion of a portion of the cells such that only the cells that are not sensitive to the illumination form an aggregate in one layer, the chip characterized in that the resonant cavity comprises walls for containing the cells originating from the passage channel, in such a way that the cells are no longer under the influence of a flow in the passage channel. - a block made from biocompatible material, - a passage channel made in the block for the passage of cells bathed in a liquid, - a resonant cavity made in the block , connected to the passage channel, - an acoustic wave generator capable of forming at least one cell aggregate in acoustic levitation in the resonant cavity, - at least one optical emitter capable of illuminating cells in the resonant cavity through at least one wall of the resonant cavity and simultaneous with the generation of acoustic waves in such a way as to structure said at least one aggregate by means of the technique of optical exclusion of a portion of the cells such that only the cells that are not sensitive to the illumination form an aggregate in one layer, the chip characterized in that the resonant cavity comprises walls for containing the cells originating from the passage channel, in such a way that the cells are no longer under the influence of a flow in the passage channel.
A coupling device intended to couple a first and a second road vehicle , these two road vehicles each comprising at least two axles , where said coupling device comprises: • a drawbar intended to be secured to the second road vehicle and comprising an end coupling eye ; and • a crossbar intended to be to the first road vehicle and comprising a drawbar coupling intended to receive the coupling eye for locking; said coupling device comprising an automatic locking mechanism provided for automatically locking the coupling eye with the drawbar coupling when it enters into the drawbar coupling following the coupling eye and the drawbar coupling coming close, and characterized in that the automatic locking mechanism comprises the following means : • a coupling pin provided in the crossbar of the first road vehicle , where this coupling pin is perpendicular to the drawbar coupling when the two road vehicles are coupled and is mobile between a locked position wherein it enters into the drawbar coupling for passing through the coupling eye and an unlocked position in which it releases the coupling eye such that the eye can be extracted from the drawbar coupling ; • a displacement device provided in the crossbar of the first road vehicle for moving the coupling pin between the locked position thereof and the unlocked position thereof; • a detection device provided in the crossbar of the first road vehicle for detecting the presence of the coupling eye in the drawbar coupling , where said detection device automatically actuates the displacement device when it detects the presence of the coupling eye in the drawbar coupling in order for the displacement device to move the coupling pin into the locked position thereof. • a drawbar intended to be secured to the second road vehicle and comprising an end coupling eye ; and • a crossbar intended to be to the first road vehicle and comprising a drawbar coupling intended to receive the coupling eye for locking; • a coupling pin provided in the crossbar of the first road vehicle , where this coupling pin is perpendicular to the drawbar coupling when the two road vehicles are coupled and is mobile between a locked position wherein it enters into the drawbar coupling for passing through the coupling eye and an unlocked position in which it releases the coupling eye such that the eye can be extracted from the drawbar coupling ; • a displacement device provided in the crossbar of the first road vehicle for moving the coupling pin between the locked position thereof and the unlocked position thereof; • a detection device provided in the crossbar of the first road vehicle for detecting the presence of the coupling eye in the drawbar coupling , where said detection device automatically actuates the displacement device when it detects the presence of the coupling eye in the drawbar coupling in order for the displacement device to move the coupling pin into the locked position thereof.
A method comprising: for a plurality of applications, at least one queue associated with a respective application of said plurality; receiving at a user equipment a scheduling grant for the at least one queue from a base station ; enabling quality of service information associated with the respective application of said plurality to be provided by the user equipment to the base station after receiving the scheduling grant for the at least one queue, the quality of service information comprising head of line delay information, the quality of service information associated with the respective application of said plurality being provided to a scheduler in the base station . receiving at a user equipment a scheduling grant for the at least one queue from a base station ; enabling quality of service information associated with the respective application of said plurality to be provided by the user equipment to the base station after receiving the scheduling grant for the at least one queue, the quality of service information comprising head of line delay information, the quality of service information associated with the respective application of said plurality being provided to a scheduler in the base station .
A device for producing three-dimensional components from a powder material by layered application of the powder material and partial solidification of the powder material of a layer by selectively irradiating points of the layer corresponding to a cross section of the component to be produced by means of at least one energy beam, comprising a construction container for accommodating the powder material, comprising a coating device for the layered application of the powder material, comprising an overflow container for accommodating an unused material residue of a production process, and comprising a trough-shaped intermediate container for accommodating the unused material residue of an application process and furthermore for delivery to the overflow container and comprising a transport device (5; 6; 7) acting in the intermediate container, characterized by a mechanical or fluidically driven continuous conveyor (5; 6) as transport device. and comprising a trough-shaped intermediate container for accommodating the unused material residue of an application process and furthermore for delivery to the overflow container and comprising a transport device (5; 6; 7) acting in the intermediate container, characterized by a mechanical or fluidically driven continuous conveyor (5; 6) as transport device.
A method to improve precision of a test result from an optical analyzer previously calibrated with an external calibrant and having stored in analyzer memory a calibration value, comprising: providing the optical analyzer comprising a normalization target embedded in or on the analyzer, the normalization target having an assigned normalization value based on its detected signal relative to the detected signal associated with the calibration value, the assigned normalization value being stored in analyzer memory; scanning or imaging in a single data collection event: (i) a test cartridge inserted into the analyzer to obtain a test signal; and (ii) the embedded normalization target to obtain a current normalization value; and adjusting the test signal by a scaling factor based on the current normalization value, thereby obtaining a scaled test result with improved precision relative to the test signal. providing the optical analyzer comprising a normalization target embedded in or on the analyzer, the normalization target having an assigned normalization value based on its detected signal relative to the detected signal associated with the calibration value, the assigned normalization value being stored in analyzer memory; scanning or imaging in a single data collection event: (i) a test cartridge inserted into the analyzer to obtain a test signal; and (ii) the embedded normalization target to obtain a current normalization value; and (i) a test cartridge inserted into the analyzer to obtain a test signal; and (ii) the embedded normalization target to obtain a current normalization value; and adjusting the test signal by a scaling factor based on the current normalization value, thereby obtaining a scaled test result with improved precision relative to the test signal.
A layer system for thin-film solar cells , comprising: - an absorber layer for absorbing light, - a buffer layer arranged on the absorber layer , containing Na x In y-x/3 S with 0.063 ≤ x ≤ 0.625, 0.681 ≤ y ≤ 1.50 wherein the percentage of all elements of Na x In y-x/3 S in the buffer layer is at least 75 atom-%, wherein in the buffer layer the ratio of the mole fractions of sodium and indium is greater than 0.2. - an absorber layer for absorbing light, - a buffer layer arranged on the absorber layer , containing Na x In y-x/3 S with 0.063 ≤ x ≤ 0.625, 0.681 ≤ y ≤ 1.50 0.063 ≤ x ≤ 0.625, 0.681 ≤ y ≤ 1.50
A slatted bed platform adapted to lay transverse to a vehicle behind one or more occupant seats inside a vehicle cabin, the bed platform comprising a supporting beam structure forming a central portion and one or more outer portions ; wherein the one or more outer portions is adapted to extend behind the seat in a lateral direction of the vehicle when the bed platform is installed in the vehicle; wherein the supporting beam structure has one or more weakened connector portions adapted to connect the said central portion to the vehicle cabin and/or the one or more outer portions; wherein the said weakened connector portion is adapted to allow the central portion to move forward past the said occupant seats and the said outer portions to remain behind the said seats by disconnection and/or deformation of weakened connector portions from the central portion. wherein the supporting beam structure has one or more weakened connector portions adapted to connect the said central portion to the vehicle cabin and/or the one or more outer portions; wherein the said weakened connector portion is adapted to allow the central portion to move forward past the said occupant seats and the said outer portions to remain behind the said seats by disconnection and/or deformation of weakened connector portions from the central portion.
A shower profile for a shower assembly comprising: a body having two elongated sections and a rounded section , wherein the rounded section connects the two elongated sections with an angle (A1), wherein the rounded section is a bent section, so as to create a soft corner once it is bent during a manufacturing process, comprising a cut-out having an opening for receiving a corner member , said cut-out being defined by first and second edges of the respective first and second elongated sections , and wherein the two elongated sections and the continuous rounded section are provided in one piece.
A 1-phenylpropanone compound of formula (I) or a pharmaceutically acceptable salt thereof wherein: X is a methylene group (-CH 2 -) or an atom selected from the group consisting of O, S and Se, n is an integer from 4 to 6, A is a substituent selected from the group consisting of 4-morpholyl, 1-piperidinyl and 4-methyl-1-piperazinyl, and it is optionally substituted with a (C 1 -C 3 )alkyl or (C 1 -C 3 )acyl radical, with the proviso that when X is CH 2 , n is equal to 5, for use as an antitumoral agent in the treatment of breast cancer, chronic lymphatic leukemia or neuroblastoma. X is a methylene group (-CH 2 -) or an atom selected from the group consisting of O, S and Se, n is an integer from 4 to 6, A is a substituent selected from the group consisting of 4-morpholyl, 1-piperidinyl and 4-methyl-1-piperazinyl, and it is optionally substituted with a (C 1 -C 3 )alkyl or (C 1 -C 3 )acyl radical, with the proviso that when X is CH 2 , n is equal to 5,