A compound of formula ( I ) : or a pharmaceutically acceptable salt or solvate thereof, wherein: m and n represent the number of amino acid residues, m is 0, and n is 1 or 2; R 4 is side chains of amino acids, and n of R 4 is independently selected from hydrogen, aralkyl, heteroaralkyl, heterocycloalkyl, alkyl, wherein the above aralkyl, heteroaralkyl, heterocycloalkyl or alkyl each can be optionally substituted by one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, heterocyclyl, heterocycloalkyl, alkoxy, cycloalkoxy, aryloxy, alkylthio, cycloalkylthio, arylthio, alkoxycarbonyl, aryloxycarbonyl, acyl, thioacyl, acyloxy, amido, carbamido, sulfinyl, alkylsulfonyl, arylsulfonyl, haloalkyl, carbamoyl, halogen, cyano, isocyano, nitro, nitroso, thiocyano, isothiocyano, acylhydrazino, thioalkyl, sulpho and silyl; R 5 and R 6 are hydrogen at the same time, or together R 5 and R 6 form diol ester group; R 1 , L and R 3 together with N atom to which L and R 3 are attached form 5, 6 or 7 membered heterocyclic ring optionally having, in addition to the nitrogen atom, another ring heteroatom being N, and optionally having an oxo group; meanwhile, the 5, 6 or 7 membered heterocyclic ring above is fused to aromatic ring or heteroaromatic ring each optionally substituted by one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, heterocyclyl, heterocycloalkyl, alkoxy, cycloalkoxy, aryloxy, alkylthio, cycloalkylthio, arylthio, alkoxycarbonyl, aryloxycarbonyl, acyl, thioacyl, acyloxy, amido, carbamido, sulfinyl, alkylsulfonyl, arylsulfonyl, haloalkyl, carbamoyl, halogen, cyano, isocyano, nitro, nitroso, thiocyano, isothiocyano, acylhydrazino, thioalkyl, sulpho and silyl. m and n represent the number of amino acid residues, m is 0, and n is 1 or 2; R 4 is side chains of amino acids, and n of R 4 is independently selected from hydrogen, aralkyl, heteroaralkyl, heterocycloalkyl, alkyl, wherein the above aralkyl, heteroaralkyl, heterocycloalkyl or alkyl each can be optionally substituted by one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, heterocyclyl, heterocycloalkyl, alkoxy, cycloalkoxy, aryloxy, alkylthio, cycloalkylthio, arylthio, alkoxycarbonyl, aryloxycarbonyl, acyl, thioacyl, acyloxy, amido, carbamido, sulfinyl, alkylsulfonyl, arylsulfonyl, haloalkyl, carbamoyl, halogen, cyano, isocyano, nitro, nitroso, thiocyano, isothiocyano, acylhydrazino, thioalkyl, sulpho and silyl; R 5 and R 6 are hydrogen at the same time, or together R 5 and R 6 form diol ester group; R 1 , L and R 3 together with N atom to which L and R 3 are attached form 5, 6 or 7 membered heterocyclic ring optionally having, in addition to the nitrogen atom, another ring heteroatom being N, and optionally having an oxo group; meanwhile, the 5, 6 or 7 membered heterocyclic ring above is fused to aromatic ring or heteroaromatic ring each optionally substituted by one or more substituents independently selected from the group consisting of alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroaralkyl, heterocyclyl, heterocycloalkyl, alkoxy, cycloalkoxy, aryloxy, alkylthio, cycloalkylthio, arylthio, alkoxycarbonyl, aryloxycarbonyl, acyl, thioacyl, acyloxy, amido, carbamido, sulfinyl, alkylsulfonyl, arylsulfonyl, haloalkyl, carbamoyl, halogen, cyano, isocyano, nitro, nitroso, thiocyano, isothiocyano, acylhydrazino, thioalkyl, sulpho and silyl. <EOS>