mhurhangee/patent-ind-claim-en huggingface dataset:
Exenatide for use in treating type 2 diabetes mellitus in a subject, wherein the subject is a human, the use comprising: providing continuous delivery of the exenatide from an osmotic delivery device, the exenatide having the amino acid sequence of exendin-4, wherein (i) substantial steady-state delivery of the exenatide at a therapeutic concentration is achieved within a time period selected from the group consisting of 5 days or less, 4 days or less, 3 days or less, 2 days or less, and 1 day or less after implantation of the osmotic delivery device in the human, and (ii) the substantial steady-state delivery of the exenatide from the osmotic delivery device is continuous over an administration period of at least 3 months at a mcg/day dose of exenatide selected from the group consisting of 10 mcg/day, 20 mcg/day, 40 mcg/day, 60 mcg/day and 80 mcg/day; wherein the use further comprises a first continuous administration period of the exenatide at a first mcg/day dose that is followed by a second continuous administration period providing a dose escalation of the exenatide to a second mcg/day dose, wherein the second mcg/day dose is greater than the first mcg/day dose. providing continuous delivery of the exenatide from an osmotic delivery device, the exenatide having the amino acid sequence of exendin-4, wherein (i) substantial steady-state delivery of the exenatide at a therapeutic concentration is achieved within a time period selected from the group consisting of 5 days or less, 4 days or less, 3 days or less, 2 days or less, and 1 day or less after implantation of the osmotic delivery device in the human, and (ii) the substantial steady-state delivery of the exenatide from the osmotic delivery device is continuous over an administration period of at least 3 months at a mcg/day dose of exenatide selected from the group consisting of 10 mcg/day, 20 mcg/day, 40 mcg/day, 60 mcg/day and 80 mcg/day; wherein the use further comprises a first continuous administration period of the exenatide at a first mcg/day dose that is followed by a second continuous administration period providing a dose escalation of the exenatide to a second mcg/day dose, wherein the second mcg/day dose is greater than the first mcg/day dose.
Assembly of a connection cable and a connecting device, more specifically an audio jack plug, said connecting device comprising: - a substantially elongated inserting member that is extending in a longitudinal direction and that is insertable into a connection jack of an electronic device , said inserting member further comprising a transverse direction extending transverse thereto, said inserting member further comprising an outer surface with at least two electrically conductive parts with insulating material arranged there between; and characterized in that the inserting member is configured to, by means of compression, clamping said at least two wire ends between an inner wall of at least one of the at least two electrically conductive parts and an outer wall of an insulation member, mechanically and electrically connect the at least two electrically conductive parts with at least two wire ends of a connection cable within the space enclosed by the outer surface of said elongated inserting member and insertable into the connection jack of the electronic device; and - wherein wires of the connection cable branch out in different directions inside the space enclosed by the outer surface of the inserting member . - a substantially elongated inserting member that is extending in a longitudinal direction and that is insertable into a connection jack of an electronic device , said inserting member further comprising a transverse direction extending transverse thereto, said inserting member further comprising an outer surface with at least two electrically conductive parts with insulating material arranged there between; and characterized in that the inserting member is configured to, by means of compression, clamping said at least two wire ends between an inner wall of at least one of the at least two electrically conductive parts and an outer wall of an insulation member, mechanically and electrically connect the at least two electrically conductive parts with at least two wire ends of a connection cable within the space enclosed by the outer surface of said elongated inserting member and insertable into the connection jack of the electronic device; and - wherein wires of the connection cable branch out in different directions inside the space enclosed by the outer surface of the inserting member .
An exhaust diffuser for a gas turbine engine , the exhaust diffuser , when in use, to be positioned downstream of and in fluid communication with a turbine of the gas turbine engine for directing hot combustion gases therethrough, the exhaust diffuser defining an axis therethrough and comprising: a radially outer diffuser section ; the radially outer diffuser section comprising an axially forward portion to be positioned about the exit of the turbine ; and a radially outer forward seal system positioned on the axially forward portion of the radially outer diffuser section and extending radially outwardly; the radially outer forward seal system comprising a seal base removably positioned in a seal pocket formed within a skin of the axially forward portion ; characterized in that the seal base comprises an axially extending hook and the seal pocket comprises a mating axially extending slot to accommodate the hook therein. a radially outer diffuser section ; the radially outer diffuser section comprising an axially forward portion to be positioned about the exit of the turbine ; and a radially outer forward seal system positioned on the axially forward portion of the radially outer diffuser section and extending radially outwardly; the radially outer forward seal system comprising a seal base removably positioned in a seal pocket formed within a skin of the axially forward portion ; characterized in that the seal base comprises an axially extending hook and the seal pocket comprises a mating axially extending slot to accommodate the hook therein.
Equipment storage means, in particular a drawer cabinet , which has a body or a frame to accommodate at least one drawer of the equipment storage means, guide means being provided, with which the at least one drawer can be pulled out and pushed in, at least one optical display means being provided, by means of which signals provided by a controller of the equipment storage means about state information of the at least one drawer can be displayed in an optically perceivable manner, at least one light-emitting means being provided, which is arranged on the frame or body of the equipment storage means and is operatively connected to the controller of the equipment storage means to supply signals, the at least one light-emitting means of the at least one drawer being switchable on and off by means of the signals provided by the controller, the optical display means provided being drawer display means, with which light transmitted/emitted by the light-emitting means in the direction of the drawer in a contactless manner can be brought to the drawer to be displayed, and characterized in that light-emitting means are arranged on two opposite sides of the body opening on the frame or body of the equipment storage means.
Method for controlling a thermal treatment system for a vehicle, the thermal treatment system comprising: - at least one refrigerant (FR) circuit comprising at least one refrigerant (FR) compression device and a first thermal exchanger configured to thermally treat a vehicle interior; - a heat transfer fluid (FC) circulation loop comprising a means for circulating the heat transfer fluid (FC) in the circulation loop and a second thermal exchanger configured to thermally treat at least one element of an electric power train of the vehicle; - a heat exchanger able to implement a thermal exchange between the refrigerant (FR) and the heat transfer fluid (FC); - the heat transfer fluid (FC) circulation loop comprising at least one bypass means configured to adapt a flow rate (Mw_e) of the heat transfer fluid (FC) in the heat exchanger , characterized in that the control method comprises a step (E) of controlling the flow rate (Mw_e) of heat transfer fluid (FC) in the heat exchanger that is carried out at least as a function of a temperature (Treo) of the refrigerant (FR) exiting the first thermal exchanger , in that the control of the flow rate (Mw_e) of heat transfer fluid (FC) in the heat exchanger takes into account a maximum speed setpoint (Vmax) of the compression device , and in that , when the maximum speed setpoint (Vmax) of the compression device is reached or exceeded, a temperature threshold value (T s ) with which the temperature (Treo) of the refrigerant exiting the first thermal exchanger is compared is increased. - at least one refrigerant (FR) circuit comprising at least one refrigerant (FR) compression device and a first thermal exchanger configured to thermally treat a vehicle interior; - a heat transfer fluid (FC) circulation loop comprising a means for circulating the heat transfer fluid (FC) in the circulation loop and a second thermal exchanger configured to thermally treat at least one element of an electric power train of the vehicle; - a heat exchanger able to implement a thermal exchange between the refrigerant (FR) and the heat transfer fluid (FC); - the heat transfer fluid (FC) circulation loop comprising at least one bypass means configured to adapt a flow rate (Mw_e) of the heat transfer fluid (FC) in the heat exchanger ,
A method of making a metal stethoscope comprising: injection molding, extruding, or pressing a metallic thermoplastic composition into a mould forming a green molded body, continuously debinding a portion of binder material from green molded body at a temperature in a range of 100 to 200°C over a period from 4 to 12 hours in a nitrogen-comprising atmosphere forming a brown molded body, wherein the temperature is maintained within ± 10 °C during the period; sintering the brown molded body at a temperature in a range from 1100 to 1500°C over a period of from 6 to 10 hours in a hydrogen or argon atmosphere to form the stethoscope chestpiece . injection molding, extruding, or pressing a metallic thermoplastic composition into a mould forming a green molded body, continuously debinding a portion of binder material from green molded body at a temperature in a range of 100 to 200°C over a period from 4 to 12 hours in a nitrogen-comprising atmosphere forming a brown molded body, wherein the temperature is maintained within ± 10 °C during the period; sintering the brown molded body at a temperature in a range from 1100 to 1500°C over a period of from 6 to 10 hours in a hydrogen or argon atmosphere to form the stethoscope chestpiece .
A fluidic testing system , comprising: a plurality of test chambers , each having a wall that defines a longest side of a given test chamber , wherein each of the plurality of test chambers has only one opening , the only one opening being through said wall of a corresponding test chamber , and wherein said wall of each test chamber is configured to be aligned substantially parallel to a gravity vector, a first inlet channel configured to flow an initial amount of liquid from an inlet port, wherein the inlet port is the only external opening to the fluidic testing system ; and a plurality of fluid splitting elements configured to split the initial liquid flowing down the first inlet channel into a plurality of second inlet channels , wherein each of the plurality of test chambers is coupled via its respective opening to only one of the plurality of second inlet channels . a plurality of test chambers , each having a wall that defines a longest side of a given test chamber , wherein each of the plurality of test chambers has only one opening , the only one opening being through said wall of a corresponding test chamber , and wherein said wall of each test chamber is configured to be aligned substantially parallel to a gravity vector, a first inlet channel configured to flow an initial amount of liquid from an inlet port, wherein the inlet port is the only external opening to the fluidic testing system ; and a plurality of fluid splitting elements configured to split the initial liquid flowing down the first inlet channel into a plurality of second inlet channels , wherein each of the plurality of test chambers is coupled via its respective opening to only one of the plurality of second inlet channels .
Metering device for the metered introduction of a pourable cleaning agent into a treatment chamber of a programme-controlled cleaning device, in particular a dishwasher , comprising a housing , a storage container which accommodates the cleaning agent, and a supporting unit which is arranged so as to be movable within the housing , and in particular rotatable about an axis of rotation , and which replaceably receives the storage container and by means of which the storage container can be transferred from a home position into a metering position and vice versa, the storage container having a storage chamber and a metering channel which opens into a metering opening , the device also comprising a discharge channel which opens into the treatment chamber via a discharge opening , and which is in fluidic connection with the metering channel when the storage container is in the metering position, the discharge channel having an in-feed opening on the metering channel side, the device also comprising a housing-side closure means which, when the storage container is in the home position, interacts with and closes the metering opening of the metering channel , characterised by a drying fan arranged on the housing on the outside of said housing , the housing having an inlet opening which interacts with the drying fan , and an outlet opening for drying air conveyed by the drying fan , the inlet opening being arranged in the vertical direction of the housing below the housing-side closure means . the device also comprising a housing-side closure means which, when the storage container is in the home position, interacts with and closes the metering opening of the metering channel , characterised by a drying fan arranged on the housing on the outside of said housing , the housing having an inlet opening which interacts with the drying fan , and an outlet opening for drying air conveyed by the drying fan , the inlet opening being arranged in the vertical direction of the housing below the housing-side closure means .
Apparatus for the conveying of viscous material from a drum-like container , which has a container bottom and a circumferential container wall , extending from the container bottom to a container upper side and is open at the container upper side , with, for closing of the container , a follower plate having a material outlet attached to a conveyor pump , wherein the follower plate is provided with an annularly circumferential wiper ring , wherein the wiper ring has a radially outwardly extending contacting part for contact against an inside face , turned toward the follower plate , of the container wall , and wherein the contacting part can be pressurised with a variable pressing force for pressing against the inside face of the container wall , characterised in that the follower plate is mounted by means of at least one vertically extending retaining rod on a horizontally extending crosspiece , which is mounted on or close to a first end on a lifting device for raising and lowering of the crosspiece , while its second end is free.
A multilayer composite material (CM) comprising at least: a) a three-dimensional matrix comprising at least a first layer i. and a second layer ii. of a fabric comprising, or consisting of a polyester fiber, wherein said first layer i. and said second layer ii. are superimposed and welded together in at least two distinct and separate points, so as to define a space S between the two layers i. and ii. and b) a composition consisting of - sodium salt of hyaluronic acid (HA), prepared starting from hyaluronic acid having a weight average molecular weight ranging from 150 to 2,000 kDa, preferably from 150 to 500 kDa, even more preferably from 150 to 250 kDa, as such, or in association with another polysaccharide, preferably with chitosan derivatized with lactose, - at least one excipient suitable for pharmaceutical use, and - possibly one or more pharmacologically and/or biologically active substance; wherein said composition b) is contained in at least a part of said space S included between the layers i. and ii., wherein fabric refers to a thin and flexible product with a flat surface produced by an interweaving of threads perpendicular to each other and said composition b) being present at least in part on the surfaces of the layers i. and ii. that are external to the intermediate space S. a) a three-dimensional matrix comprising at least a first layer i. and a second layer ii. of a fabric comprising, or consisting of a polyester fiber, wherein said first layer i. and said second layer ii. are superimposed and welded together in at least two distinct and separate points, so as to define a space S between the two layers i. and ii. and b) a composition consisting of - sodium salt of hyaluronic acid (HA), prepared starting from hyaluronic acid having a weight average molecular weight ranging from 150 to 2,000 kDa, preferably from 150 to 500 kDa, even more preferably from 150 to 250 kDa, as such, or in association with another polysaccharide, preferably with chitosan derivatized with lactose, - at least one excipient suitable for pharmaceutical use, and - possibly one or more pharmacologically and/or biologically active substance; - sodium salt of hyaluronic acid (HA), prepared starting from hyaluronic acid having a weight average molecular weight ranging from 150 to 2,000 kDa, preferably from 150 to 500 kDa, even more preferably from 150 to 250 kDa, as such, or in association with another polysaccharide, preferably with chitosan derivatized with lactose, - at least one excipient suitable for pharmaceutical use, and - possibly one or more pharmacologically and/or biologically active substance;
A use of one or more trigeminal-stimulating compounds in a fragrance composition to improve the hedonic experience, intensity, and noticeability of an odor, wherein the fragrance composition comprises: a. said one or more trigeminal-stimulating compounds; and b. optionally one or more additional fragrance compounds. a. said one or more trigeminal-stimulating compounds; and b. optionally one or more additional fragrance compounds.
A method comprising: receiving a plurality of reference signals; estimating a transmission channel for each of a plurality of precoders based on the received reference signals; receiving scaled precoded data signal information based on at least one precoder; generating a channel quality metric for each precoder based on a precoder-dependent scaled estimate of the transmission channel; selecting an index of a precoder with the largest channel quality metric; transmitting the index of a precoder with the largest channel quality metric; receiving a scaled precoded data signal based on a precoder-dependent scaling factor; estimating a demodulation reference symbol channel estimate; comparing the transmission channel estimate for the precoder used for the scaled precoded data signal with the demodulation reference symbol channel estimate; determining a precoder-dependent scale factor for the precoder by comparing the demodulation reference symbol channel estimate with the transmission channel estimate; scaling an estimate of a transmission channel based on the precoder-dependent scaling factor used for the scaled precoded data signal to generate a scaled precoder-based channel estimate; and demodulating the scaled precoded data signal. receiving a plurality of reference signals; estimating a transmission channel for each of a plurality of precoders based on the received reference signals; receiving scaled precoded data signal information based on at least one precoder; generating a channel quality metric for each precoder based on a precoder-dependent scaled estimate of the transmission channel; selecting an index of a precoder with the largest channel quality metric; transmitting the index of a precoder with the largest channel quality metric; receiving a scaled precoded data signal based on a precoder-dependent scaling factor; estimating a demodulation reference symbol channel estimate; comparing the transmission channel estimate for the precoder used for the scaled precoded data signal with the demodulation reference symbol channel estimate; determining a precoder-dependent scale factor for the precoder by comparing the demodulation reference symbol channel estimate with the transmission channel estimate; scaling an estimate of a transmission channel based on the precoder-dependent scaling factor used for the scaled precoded data signal to generate a scaled precoder-based channel estimate; and demodulating the scaled precoded data signal.
A tire conveyor for transport means, in particular vehicles , of a cableway system, comprising tires , which are arranged along a track , and comprising a drivetrain for the tires , which has at least one drive pulley , in particular a belt pulley, and at least one drive means , in particular a belt, characterized in that a guide is arranged along the track , at least in some sections, and in that at least one measurement device for measuring at least one property of the drivetrain , or of a component of the drivetrain , is displaceable on the guide .
A reciprocating compressor that compresses a gas, comprising: a piston ; a cylinder that includes a hole portion into which the piston is inserted so as to be movable in the axial direction in a reciprocating manner and includes a compression chamber which is formed in an area of the hole portion with a front end of the piston so that a gas is introduced into the compression chamber ; a crank mechanism that drives the piston so that the gas introduced into the compression chamber is compressed by the piston ; and a piston ring that is fitted to the outside of the piston and slides on an inner surface of the cylinder forming the hole portion , wherein a tapered portion is formed, at an end of a base end side of the piston , in the inner surface of the cylinder forming the hole portion , characterized by an annular member that is disposed so as to surround the outside of the piston in the radial direction; and a rod packing that is provided in an inner surface portion of the annular member and slides on an outer peripheral surface of the piston , wherein the cylinder is disposed so as to contact the annular member in the axial direction of the piston in a separable state. a piston ; a cylinder that includes a hole portion into which the piston is inserted so as to be movable in the axial direction in a reciprocating manner and includes a compression chamber which is formed in an area of the hole portion with a front end of the piston so that a gas is introduced into the compression chamber ; a crank mechanism that drives the piston so that the gas introduced into the compression chamber is compressed by the piston ; and a piston ring that is fitted to the outside of the piston and slides on an inner surface of the cylinder forming the hole portion , wherein a tapered portion is formed, at an end of a base end side of the piston , in the inner surface of the cylinder forming the hole portion , characterized by an annular member that is disposed so as to surround the outside of the piston in the radial direction; and a rod packing that is provided in an inner surface portion of the annular member and slides on an outer peripheral surface of the piston , wherein the cylinder is disposed so as to contact the annular member in the axial direction of the piston in a separable state.