mhurhangee/patent-ind-claim-en huggingface dataset:
A regional oximetry pod for driving the optical emitters of one or two regional oximetry sensors and for receiving the corresponding detector signals in response, the regional oximetry pod comprising: a dual sensor connector configured to physically attach and electrically connect one or two regional oximetry sensors; a pod housing having a first housing end and a second housing end; the dual sensor connector disposed proximate the first housing end, wherein the housing at least partially encloses the dual sensor connector ; a monitor connector disposed proximate the second housing end; an analog board disposed within the pod housing in communications with the dual sensor connector; a digital board disposed within the pod housing in communications with the monitor connector; characterized by a connector flex-circuit assembly disposed within the pod housing, the connector flex-circuit assembly including at least one flex cable , a flex-circuit socket on a first end of the at least one flex cable , and flex circuit contacts on a second end of the at least one flex cable , wherein the flex circuit contacts are connected to the dual sensor connector, and the at least one flex cable folds into a U-shape to expose the flex-circuit socket for receiving an analog board plug . a dual sensor connector configured to physically attach and electrically connect one or two regional oximetry sensors; a pod housing having a first housing end and a second housing end; the dual sensor connector disposed proximate the first housing end, wherein the housing at least partially encloses the dual sensor connector ; a monitor connector disposed proximate the second housing end; an analog board disposed within the pod housing in communications with the dual sensor connector; a digital board disposed within the pod housing in communications with the monitor connector; characterized by a connector flex-circuit assembly disposed within the pod housing, the connector flex-circuit assembly including at least one flex cable , a flex-circuit socket on a first end of the at least one flex cable , and flex circuit contacts on a second end of the at least one flex cable , wherein the flex circuit contacts are connected to the dual sensor connector, and the at least one flex cable folds into a U-shape to expose the flex-circuit socket for receiving an analog board plug .
A cell sheet highly producing hyaluronic acid, wherein the cells are any one of cells among oral mucosal cells, limbal epithelial cells, corneal epithelial cells, conjunctival epithelial cells, chondrocytes, synovial cells, epidermal keratinocytes, smooth muscle cells, vascular endothelial cells, fibroblasts and mammary epithelial cells, or a mixture of two or more types thereof, wherein the cell sheet is obtainable by culturing the cells on a surface of a substrate and harvesting the cells in the form of a sheet, wherein the cells have stem cells thereof contained therein, and wherein the stem cell content in the cultured cells is at least 0.5%, and wherein the cell sheet is detached, as adhered to a carrier, from a cell culture support having a substrate surface coated with a temperature-responsive polymer whose upper or lower critical solution temperature in water is 0 to 80°C.
A system for ophthalmic intervention on an eye of a patient, comprising: a. an imaging device having a field of view oriented toward the eye of the patient; b. a patient interface housing having proximal and distal ends and defining a passage therethrough, wherein the distal end is coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to a patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and c. two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that the registration fiducials can be located by the imaging device in reference to predetermined geometric markers on the eye of the patient, the system being operable to locate the geometric markers; characterized in that : the system is configured to use the detected locations of the registration fiducials to determine an angular orientation of the patient interface housing relative to the eye. a. an imaging device having a field of view oriented toward the eye of the patient; b. a patient interface housing having proximal and distal ends and defining a passage therethrough, wherein the distal end is coupled to one or more seals configured to be directly engaged with one or more surfaces of the eye of the patient, and wherein the proximal end is configured to be coupled to a patient workstation such that at least a portion of the field of view of the imaging device passes through the passage; and c. two or more registration fiducials coupled to the patient interface housing in a predetermined geometric configuration relative to the patient interface housing within the field of view of the imaging device such that the registration fiducials can be located by the imaging device in reference to predetermined geometric markers on the eye of the patient, the system being operable to locate the geometric markers; characterized in that : the system is configured to use the detected locations of the registration fiducials to determine an angular orientation of the patient interface housing relative to the eye.
A pharmaceutical composition adapted for oral administration comprising: (a) a carrier comprising microcrystalline cellulose particles comprising on or in said carrier about 0.65% w/w hydrocortisone of the composition and, a binding agent comprising hydroxypropylmethylcellulose wherein hydroxypropylmethylcellulose is provided between 0.1-5.0% w/w of the composition (b) a sealing layer comprising hydroxypropylmethylcellulose (c) and a taste masking polymer layer contacting said sealing layer, wherein the sealing layer is between the hydroxypropylmethylcellulose and hydrocortisone and the taste masking layer, and wherein said composition is for use in the treatment of adrenal insufficiency in paediatric and elderly subjects. (a) a carrier comprising microcrystalline cellulose particles comprising on or in said carrier about 0.65% w/w hydrocortisone of the composition and, a binding agent comprising hydroxypropylmethylcellulose wherein hydroxypropylmethylcellulose is provided between 0.1-5.0% w/w of the composition (b) a sealing layer comprising hydroxypropylmethylcellulose (c) and a taste masking polymer layer contacting said sealing layer,
Method for foaming in-situ of a top material comprising the method steps of - providing a reactive foam material in the form of a liquid as foam layer with an initial height (h 0 ), - - at least partially foaming the foam material , - limiting a height expansion of the foam layer during partial foaming up to a first height (h 1 ), wherein h 1 > h 0 , - wetting and impregnating an upper contact surface of the foam layer with a reaction aid, - arranging the top material on the contact surface of the foam layer, characterised in that the method further comprises the following method step: - bonding the at least partially foamed foam layer on the contact surface with the top material to form a composite material by means of a second height limit (7; 7a). - providing a reactive foam material in the form of a liquid as foam layer with an initial height (h 0 ), - - at least partially foaming the foam material , - limiting a height expansion of the foam layer during partial foaming up to a first height (h 1 ), wherein h 1 > h 0 , - wetting and impregnating an upper contact surface of the foam layer with a reaction aid, - arranging the top material on the contact surface of the foam layer, - bonding the at least partially foamed foam layer on the contact surface with the top material to form a composite material by means of a second height limit (7; 7a).
A rapid method of determining warfarin sensitivity for use in a microfluidic device comprising; contacting Z a sample with pairs of oligonucleotide primers, each pair comprising a forward primer and a reverse primer, wherein the pairs of oligonucleotide primers comprise; Primer name Sequence SEQ ID ∗ 2_v1_F GGCGTTTCTCCCTCATGACGC SEQ ID 1 ∗ 2_v1_R GAGTAGGGTCACCCACCCTTGG SEQ ID 2 ∗ 3_v1_F GCAAGACAGGAGCCACATGCC SEQ ID 3 ∗ 3_v2_R or ∗ 3_v2_R' GAATTTAATGTCACAGGTCACTGC SEQ ID 4 CTGAATTTAATGTCACAGGTCACTGCATG SEQ ID 13 VK_v1_F GGATTATAGGCGTGAGCCACC SEQ ID 5 VK_v1_R GGTAGGTGCAACAGTAAGGGATCC SEQ ID 6 or wherein the pairs of oligonucleotide primers have at least 80% sequence homology to the primers identified as SEQ ID 1, 2, 3, 4, 5 and 6; and are operable to bind genomic regions flanking CYP2C9 ∗ 2 (rs1799853), CYP2C9 ∗ 3 (rs1057910) and VKORC1 - 1639G>A (rs9923231) single nucleotide polymorphism (SNP) sites and to amplify genomic regions to give amplicons comprising said SNP sites; amplifying, substantially simultaneously, the SNP sites by polymerase chain reaction by annealing the primer pairs to the nucleic acid present in the sample; simultaneously extending the annealed primers to synthesize an extension product, wherein each extension product after separation from the nucleic acid, serves as a template for the synthesis of an extension product for the other primer of each pair; and detecting the amplified products, if present, to indicate the presence or absence of a single nucleotide polymorphism (SNP) associated with warfarin sensitivity in the sample, wherein detection of single nucleotide polymorphisms is indicative of warfarin sensitivity. or wherein the pairs of oligonucleotide primers have at least 80% sequence homology to the primers identified as SEQ ID 1, 2, 3, 4, 5 and 6; and are operable to bind genomic regions flanking CYP2C9 ∗ 2 (rs1799853), CYP2C9 ∗ 3 (rs1057910) and VKORC1 - 1639G>A (rs9923231) single nucleotide polymorphism (SNP) sites and to amplify genomic regions to give amplicons comprising said SNP sites; amplifying, substantially simultaneously, the SNP sites by polymerase chain reaction by annealing the primer pairs to the nucleic acid present in the sample; simultaneously extending the annealed primers to synthesize an extension product, wherein each extension product after separation from the nucleic acid, serves as a template for the synthesis of an extension product for the other primer of each pair; and detecting the amplified products, if present, to indicate the presence or absence of a single nucleotide polymorphism (SNP) associated with warfarin sensitivity in the sample, wherein detection of single nucleotide polymorphisms is indicative of warfarin sensitivity.
A tangential on-board injector (TOBI) of a gas turbine engine , comprising: a body defining an annular passageway configured to receive cooling air, the TOBI defining a plurality of discharge nozzles ; a rotating component configured to be mounted for rotation relative to the body about an axis of rotation ; characterised by a brush seal (37;137) extending between the body and the rotating component, the brush seal (37; 137) including an annular brush and an annular plate (37C; 137C) located upstream of the annular brush ; and flow passages (52;152;252) circumferentially distributed about the axis of rotation and defined through the annular plate (37C; 137C), in fluid communication with the nozzles and the seal (37;137), the flow passages (52;152;252) located upstream of the seal (37;137) relative to a flow of the cooling air circulating toward the seal (37;137) from the plurality of discharge nozzles , each of the flow passages (52;152;252) extending along a respective passage axis (H), and the passage axis (H) of at least one of the flow passages (52;152;252) having a tangential component at an outlet of the at least one of the flow passages (52;152;252) that is different than a tangential component of an exit flow axis (A) of at least one of the plurality of discharge nozzles . a body defining an annular passageway configured to receive cooling air, the TOBI defining a plurality of discharge nozzles ; a rotating component configured to be mounted for rotation relative to the body about an axis of rotation ; characterised by a brush seal (37;137) extending between the body and the rotating component, the brush seal (37; 137) including an annular brush and an annular plate (37C; 137C) located upstream of the annular brush ; and flow passages (52;152;252) circumferentially distributed about the axis of rotation and defined through the annular plate (37C; 137C), in fluid communication with the nozzles and the seal (37;137), the flow passages (52;152;252) located upstream of the seal (37;137) relative to a flow of the cooling air circulating toward the seal (37;137) from the plurality of discharge nozzles , each of the flow passages (52;152;252) extending along a respective passage axis (H), and the passage axis (H) of at least one of the flow passages (52;152;252) having a tangential component at an outlet of the at least one of the flow passages (52;152;252) that is different than a tangential component of an exit flow axis (A) of at least one of the plurality of discharge nozzles .
Disc brake, in particular for utility vehicles, comprising a brake disc, a brake shaft , of which the axis of rotation (D) is located parallel to a main plane (E) of the brake disc, a brake caliper , in particular a sliding caliper, on which the brake shaft is supported when actuated via a sliding block , a brake pad , located on the same side as the brake shaft with respect to the brake disc, a pressure piece between the brake shaft and the brake pad, a first restricting device (52, 54; 56, 58), which restricts the displaceability of the pressure piece with respect to the brake disc in the direction parallel to the axis of rotation of the brake shaft to a predetermined first dimension, and a second restricting device (40, 44, 46; 42, 48, 50), which restricts the displaceability of the brake shaft with respect to the brake disc in the direction parallel to the axis of rotation of the brake shaft to a predetermined second dimension, wherein the brake shaft, when actuated, presses the pressure piece and therefore the brake pad against the brake disc, the second restricting device (40, 44, 46; 42, 48, 50) has a first stop on the pressure piece and a second stop on the brake shaft , which interacts with the first stop with the effect of restricting the displaceability, a third restricting device (22, 24; 26, 28) is provided, which restricts the displaceability of the sliding block with respect to the brake disc in at least one direction located parallel to the main plane (E) of the brake disc to a predetermined third dimension, and the third restricting device (22, 24; 26, 28) has a projection which, when assembled, projects into a recess (26; 28), characterized in that the recess (26; 28) is a blind hole.
Prefabricated part with a concrete body which has the shape of a pipe section with two pipe ends and an inner pipe side , wherein the inner pipe side is lined at least in some areas by a lining made of thermoplastic material connected to the concrete body and at least one of the pipe ends is covered at least in some areas by a molded part made of thermosetting plastic material connected to the concrete body , wherein at least the pipe end , which is covered at least in some areas, has a connecting joint in order to connect the pipe end to one pipe end of a further prefabricated part , and wherein the lining and the molded part overlap each other in an overlap area and are connected to each other in a sealed manner, characterized in in that a strip made of a thermoplastic material is arranged in the overlap area between the molded part and the lining , in that the strip is connected to the molded part by one or more fastener/s, which is/are at least partially embedded respectively accommodated both in the strip and in the molded part and in that the strip is connected to the lining by a joining connection.
A jounce control damping system comprising: - an elongated housing containing a damping medium; - a moveable outer piston assembly disposed within the housing; - a movable inner piston assembly disposed at least partially within the outer piston assembly; - said inner piston assembly being configured to engage a primary piston assembly as said primary piston assembly is moved beyond a first compression movement distance causing the inner piston assembly to move in the compressive direction; and - said outer piston assembly being configured to move in the compressive direction in response to the inner piston assembly moving in the compressive direction beyond a second compressive movement distance, - wherein the primary piston assembly provides a first compression damping force during the first compression movement distance of the primary piston; - wherein the inner piston assembly provides a second compression damping force during the second compression movement distance of the inner piston assembly and the outer piston assembly provides a third compression damping force greater than the second compression damping force during the third compression movement distance; - a second housing , wherein the outer piston assembly is disposed and moveable within the second housing , and wherein the second housing is formed integral with the elongated housing . - an elongated housing containing a damping medium; - a moveable outer piston assembly disposed within the housing; - a movable inner piston assembly disposed at least partially within the outer piston assembly; - said inner piston assembly being configured to engage a primary piston assembly as said primary piston assembly is moved beyond a first compression movement distance causing the inner piston assembly to move in the compressive direction; and - said outer piston assembly being configured to move in the compressive direction in response to the inner piston assembly moving in the compressive direction beyond a second compressive movement distance, - wherein the primary piston assembly provides a first compression damping force during the first compression movement distance of the primary piston; - wherein the inner piston assembly provides a second compression damping force during the second compression movement distance of the inner piston assembly and the outer piston assembly provides a third compression damping force greater than the second compression damping force during the third compression movement distance; - a second housing , wherein the outer piston assembly is disposed and moveable within the second housing , and wherein the second housing is formed integral with the elongated housing .
An aircraft passenger accommodation unit for location adjacent to an aisle in an aircraft cabin, the unit comprising: - a seat , having a seat pan and a seat back , - a shell , at least partially surrounding the seat , wherein the shell defines an opening that allows a passenger egress between the aisle and the seat through the opening, and - a door assembly , for providing variable access through the opening between the aisle and the seat , wherein the door assembly comprises a door rotatably mounted relative to the shell , such that the door is rotatable between an open position which allows passenger egress through the opening, and a closed position in which passenger egress through the opening is at least partially blocked, wherein the door is rotatable between the open and closed positions in a plane of rotation of the door , the plane of rotation extending across the opening, wherein the door assembly further comprises a privacy screen movably mounted to the door , the privacy screen being moveable across the opening between a retracted position, which allows passenger egress between the seat and the aisle through the opening, and an extended position, in which passenger egress between the aisle and the seat through the opening is at least partially blocked by the privacy screen . - a seat , having a seat pan and a seat back , - a shell , at least partially surrounding the seat , wherein the shell defines an opening that allows a passenger egress between the aisle and the seat through the opening, and - a door assembly , for providing variable access through the opening between the aisle and the seat , wherein the door assembly comprises a door rotatably mounted relative to the shell , such that the door is rotatable between an open position which allows passenger egress through the opening, and a closed position in which passenger egress through the opening is at least partially blocked, wherein the door is rotatable between the open and closed positions in a plane of rotation of the door , the plane of rotation extending across the opening, wherein the door assembly further comprises a privacy screen movably mounted to the door , the privacy screen being moveable across the opening between a retracted position, which allows passenger egress between the seat and the aisle through the opening, and an extended position, in which passenger egress between the aisle and the seat through the opening is at least partially blocked by the privacy screen .
Fastening element for arrangement on a connecting element of a process container , in particular a reactor, preferably a bioreactor, most preferably a single-use bioreactor, wherein the fastening element has a nozzle and a fixing element , wherein the nozzle has a sensor opening for inserting a sensor into the nozzle and a measuring window on a side opposite the sensor opening, and wherein the fixing element is designed to arrange the nozzle on the connecting element of the process container , characterized in that the fixing element has at least one latching arm with a movable latching region in order to form a latching connection with the connecting element of the process container , and the fixing element has at least one securing element arranged displaceably on the fixing element , wherein the securing element and the fixing element are designed to interact in such a way that, when the securing element is in an insertion position (E), the latching region of the at least one latching arm is movable and, when the securing element is in a securing position (S), a movement of the latching region of the at least one latching arm is prevented by the securing element . wherein the fastening element has a nozzle and a fixing element , wherein the nozzle has a sensor opening for inserting a sensor into the nozzle and a measuring window on a side opposite the sensor opening, and wherein the fixing element is designed to arrange the nozzle on the connecting element of the process container , characterized in that the fixing element has at least one latching arm with a movable latching region in order to form a latching connection with the connecting element of the process container , and the fixing element has at least one securing element arranged displaceably on the fixing element , wherein the securing element and the fixing element are designed to interact in such a way that, when the securing element is in an insertion position (E), the latching region of the at least one latching arm is movable and, when the securing element is in a securing position (S), a movement of the latching region of the at least one latching arm is prevented by the securing element .