A compound having the formula: wherein R 7 represents a substituent selected from the group consisting of substituted or unsubstituted quinolinyl and substituted or unsubstituted isoquinolinyl; R 8 represents a substituent selected from the group consisting of H, OH, NO 2 , CN, halo, and substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, amino, and alkoxy; R 9 , R 10 , R 11 , R 12 , and R 13 each can independently represent a substituent selected from the group consisting of H, OH, NO 2 , CN, halo, and substituted or unsubstituted alkyl, alkylcarbonyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocycle, heteroaryl, amino, alkoxy, carboxy, carbalkoxy, carboxamido, sulfonyl, sulfonamido, sulfinyl, monoalkylaminosulfinyl, dialkylaminosulfinyl, monoalkylaminosulfonyl, dialkylaminosulfonyl, alkylsulfonylamino, hydroxysulfonyloxy, alkoxysulfonyloxy, alkylsulfonyloxy, hydroxysulfonyl, alkoxysulfonyl, alkylsulfonylalkyl, monoalkylaminosulfonylalkyl, dialkylaminosulfonylalkyl, monoalkylaminosulfinylalkyl, and dialkylaminosulfinylalkyl; X 4 represents N; X 5 represents N; wherein "substituted" means a substitution with a substituent selected from the group consisting of hydroxy, halogen, thio, cyano, alkylthio, carboxy, oxo, nitro, alkoxy, alkyl, amino, alkylamido, alkanoylamino, arylcarbonylamino, alkenyl, carboxamido, carbalkoxy, alkynyl, acyl, heterocyclyl, aryl, and heteroaryl, and wherein "substituted heteroaryl" includes fused heteroaryl groups selected from the group consisting of quinoline, isoquinoline, indole, isoindole, carbazole, acridine, benzopyrene, benzopyrone, benzimidazole, benzofuran, isobenzofuran, phenanthroline, and purine, or the pharmaceutically acceptable salts of said compound. wherein R 7 represents a substituent selected from the group consisting of substituted or unsubstituted quinolinyl and substituted or unsubstituted isoquinolinyl; R 8 represents a substituent selected from the group consisting of H, OH, NO 2 , CN, halo, and substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, amino, and alkoxy; R 9 , R 10 , R 11 , R 12 , and R 13 each can independently represent a substituent selected from the group consisting of H, OH, NO 2 , CN, halo, and substituted or unsubstituted alkyl, alkylcarbonyl, alkenyl, alkynyl, cycloalkyl, aryl, heterocycle, heteroaryl, amino, alkoxy, carboxy, carbalkoxy, carboxamido, sulfonyl, sulfonamido, sulfinyl, monoalkylaminosulfinyl, dialkylaminosulfinyl, monoalkylaminosulfonyl, dialkylaminosulfonyl, alkylsulfonylamino, hydroxysulfonyloxy, alkoxysulfonyloxy, alkylsulfonyloxy, hydroxysulfonyl, alkoxysulfonyl, alkylsulfonylalkyl, monoalkylaminosulfonylalkyl, dialkylaminosulfonylalkyl, monoalkylaminosulfinylalkyl, and dialkylaminosulfinylalkyl; X 4 represents N; X 5 represents N; wherein "substituted" means a substitution with a substituent selected from the group consisting of hydroxy, halogen, thio, cyano, alkylthio, carboxy, oxo, nitro, alkoxy, alkyl, amino, alkylamido, alkanoylamino, arylcarbonylamino, alkenyl, carboxamido, carbalkoxy, alkynyl, acyl, heterocyclyl, aryl, and heteroaryl, and wherein "substituted heteroaryl" includes fused heteroaryl groups selected from the group consisting of quinoline, isoquinoline, indole, isoindole, carbazole, acridine, benzopyrene, benzopyrone, benzimidazole, benzofuran, isobenzofuran, phenanthroline, and purine, <EOS>