mhurhangee/patent-ind-claim-en huggingface dataset:
A modified relaxin polypeptide comprising a non-naturally encoded amino acid, wherein: (a) the modified relaxin polypeptide comprises the relaxin A chain polypeptide of SEQ ID NO: 4 and the relaxin B chain polypeptide of SEQ ID NO: 5 or SEQ ID NO: 6, substituted with a non-naturally encoded amino acid at A chain residue 1, and the modified relaxin polypeptide has 0, 1 or 2 additional amino acid substitutions, insertions and/or deletions in said relaxin A chain and/or said relaxin B chain; (b) said non-naturally encoded amino acid has the structure: wherein the R group is any substituent other than the side chain found in alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine or valine; (c) said non-naturally encoded amino acid is linked to a pharmacokinetic enhancer comprising a peptide component between 2 and 30 amino acids and a half-life extending moiety; and (d) said peptide component comprises GGGGS-Glu γ (SEQ ID NO: 139), DRDDRD (SEQ ID NO: 102), KKKKKK-Glu γ (SEQ ID NO: 103), RGGEEKKKEKEK-Glu γ (SEQ ID NO: 104), GGGEEE-Glu γ (SEQ ID NO: 105), EEEGGG-Glu γ (SEQ ID NO: 106), KKKGGG-Glu γ (SEQ ID NO: 107), GGGKKK-Glu γ (SEQ ID NO: 109), GSHHHHHGS-Glu γ (SEQ ID NO: 110), Sar-Sar-Sar-Sar-Ser-Glu γ (SEQ ID NO: 112), Sar-Sar-Sar-Glu-Glu-Glu γ (SEQ ID NO: 113), or KSGGSGG-Glu γ (SEQ ID NO: 117), or preferably comprises Glu γ , more preferably comprises GGGGS-Glu γ (SEQ ID NO: 139); and wherein said modified relaxin polypeptide is biologically active. (a) the modified relaxin polypeptide comprises the relaxin A chain polypeptide of SEQ ID NO: 4 and the relaxin B chain polypeptide of SEQ ID NO: 5 or SEQ ID NO: 6, substituted with a non-naturally encoded amino acid at A chain residue 1, and the modified relaxin polypeptide has 0, 1 or 2 additional amino acid substitutions, insertions and/or deletions in said relaxin A chain and/or said relaxin B chain; (b) said non-naturally encoded amino acid has the structure: wherein the R group is any substituent other than the side chain found in alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine or valine; (c) said non-naturally encoded amino acid is linked to a pharmacokinetic enhancer comprising a peptide component between 2 and 30 amino acids and a half-life extending moiety; and (d) said peptide component comprises GGGGS-Glu γ (SEQ ID NO: 139), DRDDRD (SEQ ID NO: 102), KKKKKK-Glu γ (SEQ ID NO: 103), RGGEEKKKEKEK-Glu γ (SEQ ID NO: 104), GGGEEE-Glu γ (SEQ ID NO: 105), EEEGGG-Glu γ (SEQ ID NO: 106), KKKGGG-Glu γ (SEQ ID NO: 107), GGGKKK-Glu γ (SEQ ID NO: 109), GSHHHHHGS-Glu γ (SEQ ID NO: 110), Sar-Sar-Sar-Sar-Ser-Glu γ (SEQ ID NO: 112), Sar-Sar-Sar-Glu-Glu-Glu γ (SEQ ID NO: 113), or KSGGSGG-Glu γ (SEQ ID NO: 117), or preferably comprises Glu γ , more preferably comprises GGGGS-Glu γ (SEQ ID NO: 139); and wherein said modified relaxin polypeptide is biologically active.
A de-icing apparatus for an aircraft, said apparatus comprising an electrically operable heater , an electrical actuator and a laminate structure encapsulating the electrically operable heater and the electrical actuator, wherein the laminate structure comprises a plurality of layers and wherein at least two layers are configured to be selectively movable relative to each other to increase the separation of the two layers, wherein the laminate structure comprises from an upper surface to a bottom layer: a first thermoplastic heat dissipation layer forming the upper surface of the deicing apparatus; a second electrically operable heating element layer comprising the electrically operable heater ; a third electrically insulating thermoplastic layer ; a fourth electrically insulating thermoplastic layer ; a fifth electrical power supply layer ; and a sixth thermoplastic backing layer forming the bottom layer arranged for connection to an outer surface of the aircraft; wherein the electrical actuator is located between the third and fourth thermoplastic layers. a first thermoplastic heat dissipation layer forming the upper surface of the deicing apparatus; a second electrically operable heating element layer comprising the electrically operable heater ; a third electrically insulating thermoplastic layer ; a fourth electrically insulating thermoplastic layer ; a fifth electrical power supply layer ; and a sixth thermoplastic backing layer forming the bottom layer arranged for connection to an outer surface of the aircraft; wherein the electrical actuator is located between the third and fourth thermoplastic layers.
Vehicle for handling materials and earthmoving, comprising a dashboard , wherein the dashboard comprises a liquid reservoir , characterize in that said liquid reservoir is formed in one piece with the rest of the dashboard .
A method for producing slat layers from slats arranged behind one another, wherein the slats are placed behind one another such that the sum of the slat length corresponds at least to the length of the slat layer to be produced, wherein at least one buffer station is provided for the slats of different lengths , from which buffer station the slats are removed for forming the slat layers , wherein the slats are combined on a conveying means such that the end slat inside the slat layer is so long and is severed such that the slat layer has the desired length , and the severed remaining piece of the end slat can be inserted into a subsequent slat layer , characterized in that the remaining piece of the end slat is taken from the conveying stream, is temporarily stored on a remaining piece conveying means , and is inserted in a subsequent slat layer according to a slat , wherein the severed remaining piece does not form the first piece of a directly next, subsequent slat layer .
A mobile terminal comprising: a display configured to display a first wallpaper (W1) of a plurality of wallpapers (W) including at least one object (WD, I); a controller configured to: display at least two of the plurality of wallpapers (W) on the display in response to receiving an input to add a further object to one of the plurality of wallpapers (W); and characterised in that the controller is further configured to: inactivate an area of the displayed at least two of the plurality of wallpapers (W) that has no vacancy (V) to prevent that the further object is placed in that inactivated area, wherein the controller is configured to darken the inactivated area on the display ; and activate an area of the displayed at least two of the plurality of wallpapers (W) that has a vacancy (V) to add the further object. a display configured to display a first wallpaper (W1) of a plurality of wallpapers (W) including at least one object (WD, I); a controller configured to: display at least two of the plurality of wallpapers (W) on the display in response to receiving an input to add a further object to one of the plurality of wallpapers (W); and inactivate an area of the displayed at least two of the plurality of wallpapers (W) that has no vacancy (V) to prevent that the further object is placed in that inactivated area, wherein the controller is configured to darken the inactivated area on the display ; and activate an area of the displayed at least two of the plurality of wallpapers (W) that has a vacancy (V) to add the further object.
A pot-hole test system for a heavy vehicle comprising a pot-hole track (P) made on a ground (T) and a heavy vehicle , said track (P) defining a plurality of holes (B) and bumps (D) along a direction parallel to a longitudinal axis (A) of said heavy vehicle , characterized in said heavy vehicle comprising a towing cab and a trailer selectively connectable to said cab through connection means , said cab and said trailer each being provided with a plurality of wheels configured to allow the movement of said heavy vehicle on said ground (T), said wheels of said trailer being arranged transversely to the longitudinal axis (A) of said heavy vehicle at a greater distance from the latter than said wheels of said cab so as to not be in contact with said track (P).
A method for sequential handovers, the method comprising: receiving , by a source access point , a handover request from a leading vehicle in a platoon of vehicles, the leading vehicle being followed by one or more trailing vehicles , wherein the handover request requests a handover from a source access point to a target access point ; obtaining information about the platoon from the handover request or an independent signaling, wherein the information about the platoon comprises a current speed of the platoon, and a vehicle spacing; and transmitting by the source access point , handover commands to the one or more trailing vehicles in response to the handover request received from the leading vehicle , wherein each handover command is used to instruct a respective trailing vehicle to perform uplink random access transmission to the target access point during a time period [t-Δ, t], wherein the Δ is a duration in which a handover process of a trailing vehicle should be initiated, and t = t 0 + n × δ, where t 0 is a time of the respective trailing vehicle receiving the handover command , n is an index of the respective trailing vehicle in the platoon, and δ is a time duration for the respective trailing vehicle to cover a length equal to a trailing vehicle length plus the vehicle spacing. receiving , by a source access point , a handover request from a leading vehicle in a platoon of vehicles, the leading vehicle being followed by one or more trailing vehicles , wherein the handover request requests a handover from a source access point to a target access point ; obtaining information about the platoon from the handover request or an independent signaling, wherein the information about the platoon comprises a current speed of the platoon, and a vehicle spacing; and transmitting by the source access point , handover commands to the one or more trailing vehicles in response to the handover request received from the leading vehicle , wherein each handover command is used to instruct a respective trailing vehicle to perform uplink random access transmission to the target access point during a time period [t-Δ, t], wherein the Δ is a duration in which a handover process of a trailing vehicle should be initiated, and t = t 0 + n × δ, where t 0 is a time of the respective trailing vehicle receiving the handover command , n is an index of the respective trailing vehicle in the platoon, and δ is a time duration for the respective trailing vehicle to cover a length equal to a trailing vehicle length plus the vehicle spacing.
Longitudinal conveyer, in particular roller track, for conveying piece goods, consisting of a number of rotatably driven conveying means, preferably conveying rollers , which are mounted rotatably on axle bolts with mutual spacing in the side walls of a longitudinal profile and have a paired drive formed by drive belts , wherein for the paired drive, each driven conveying roller has a drive wheel wrapped around by two drive belts , characterised in that an anti-pinch device with an end shield , which is penetrated by the axle bolt of the conveying roller , is assigned to each drive wheel of the conveying means, preferably the conveying roller , and rests flat on the inner side of the side wall of the longitudinal profile and in that at least two cover plates having a mutual distance from one another and approximately parallel to one another are attached releasably to the end shield , which cover plates at least partly cover the drive wheel of the conveying roller and in that attachment of the cover plates on the end shield is configured to be pluggable and in that the plug connection between the end shield and the cover plates consists of locking bolts moulded on the cover plates which engage releasably in assigned plug openings of the end shield and in that the end shield supports a sleeve shoulder which is penetrated by the axle bolt of the conveying roller .
A device , comprising: a memory ; and a processor operatively coupled to the memory and comprising computer executable components comprising: a determination component that determines wear state information representative of a wear state of a tire of a vehicle based on an output from a sensor of the vehicle ; and an alert component that, in response to the wear state of the tire being determined to exceed a tire wear threshold, generates an alert signal associated with the wear state of the tire, characterized in that the sensor comprises a brake force sensor, and wherein the output comprises a braking force applied to the vehicle . a memory ; and a processor operatively coupled to the memory and comprising computer executable components comprising: a determination component that determines wear state information representative of a wear state of a tire of a vehicle based on an output from a sensor of the vehicle ; and an alert component that, in response to the wear state of the tire being determined to exceed a tire wear threshold, generates an alert signal associated with the wear state of the tire, a determination component that determines wear state information representative of a wear state of a tire of a vehicle based on an output from a sensor of the vehicle ; and an alert component that, in response to the wear state of the tire being determined to exceed a tire wear threshold, generates an alert signal associated with the wear state of the tire,
A system for the treatment of containers made of plastic, in particular, made of PET, PE, PP or POC, comprising a cleaning machine, wherein it has a plurality of treatment stages, in which the container interior can be rinsed with liquid media and wherein at least one of the treatment stages - is a lye treatment that comprises a heating device and/or is connected to such a device and - a treatment step is a water treatment, wherein a coating device is provided downstream of the cleaning machine, wherein the cleaning machine is connected to the coating device by transport means for the containers, characterized in that the coating device is a gas separation device by means of plasma, which comprises a plurality of vacuum chambers in which the containers can be coated under a vacuum, and wherein the vacuum chamber for gas pipelines is connected to at least two different process-gas sources, and wherein at least one microwave generator or at least one high-frequency generator is provided for forming plasma. - is a lye treatment that comprises a heating device and/or is connected to such a device and - a treatment step is a water treatment, a coating device is provided downstream of the cleaning machine, wherein the cleaning machine is connected to the coating device by transport means for the containers, characterized in that the coating device is a gas separation device by means of plasma, which comprises a plurality of vacuum chambers in which the containers can be coated under a vacuum, and wherein the vacuum chamber for gas pipelines is connected to at least two different process-gas sources, and wherein at least one microwave generator or at least one high-frequency generator is provided for forming plasma.
An internal combustion engine comprising a control system , said internal combustion engine comprising a turbocharging unit and an exhaust gas recirculation assembly , said control system being adapted to issue a boost pressure control signal, said control system comprising a boost pressure controller adapted to determine said boost pressure control signal, said boost pressure controller having a first response time (T 1 ), said control system being adapted to issue an exhaust gas recirculation control signal for controlling an amount of recirculated exhaust gas via said exhaust gas recirculation assembly , wherein said internal combustion engine comprises a boost pressure regulator , said control system being adapted to issue said boost pressure control signal to said boost pressure regulator , said control system comprising an exhaust gas recirculation control system which in turn comprises an exhaust gas recirculation controller adapted to determine said exhaust gas recirculation control signal independently of said boost pressure control signal, said exhaust gas recirculation controller having a second response time (T 2 ), wherein said first response time (T 1 ) differs from said second response time (T 2 ), characterized in that said exhaust gas recirculation control system is adapted to issue a control signal to said boost pressure regulator .
A vehicle image display apparatus comprising: a synthesizing device that is configured to synthesize a rear image and a rear side image to generate a synthesized image , wherein the rear image is captured by a rear imaging device that is configured to image a rear area located at the rear of a vehicle and the rear side image is captured by a rear side imaging device that is configured to image a rear side area located at the rear and the side of the vehicle; and a displaying device that is configured to display the synthesized image, characterized in that the synthesizing device being configured to generate the synthesized image so that the synthesized image generated when the vehicle goes in reverse includes a first scene that is below, viewed from the vehicle, a second scene that is included in the synthesized image generated when the vehicle does not go in reverse. a synthesizing device that is configured to synthesize a rear image and a rear side image to generate a synthesized image , wherein the rear image is captured by a rear imaging device that is configured to image a rear area located at the rear of a vehicle and the rear side image is captured by a rear side imaging device that is configured to image a rear side area located at the rear and the side of the vehicle; and a displaying device that is configured to display the synthesized image, characterized in that the synthesizing device being configured to generate the synthesized image so that the synthesized image generated when the vehicle goes in reverse includes a first scene that is below, viewed from the vehicle, a second scene that is included in the synthesized image generated when the vehicle does not go in reverse.
An alkali metal salt of 4-chloro-N-[2-[(4-chlorophenyl)methyl]-3-oxo-1,2,4-thiadiazol-5-yl]benzamide.
Domestic appliance for food processing, having a container , wherein the container has a handle , a circumferential outer side wall and at least one opening on the top, wherein the container has at least one fastening element integral with the side wall , characterised in that the fastening element is a hook and extends outwards from the side wall in a first direction and extends substantially parallel to the side wall in a second direction, wherein the handle enters into a form-locking connection with the container via the at least one fastening element , characterised in that the domestic appliance has a housing, the housing further comprising: an electrically operated active element, a safety device which is arranged in the circuit for the current supply to the active element and only closes the circuit when the safety device is actuated, a base, wherein the base is designed to receive the container , a lid , wherein the lid is designed to close the first opening of the container , wherein the handle substantially extends over the entire height of the container and has a cavity, wherein a safety element is arranged in the cavity, wherein the safety element is arranged in such a way that it actuates the safety device when the container is closed with the lid . wherein the container has at least one fastening element integral with the side wall , characterised in that the fastening element is a hook and extends outwards from the side wall in a first direction and extends substantially parallel to the side wall in a second direction, wherein the handle enters into a form-locking connection with the container via the at least one fastening element , characterised in that the domestic appliance has a housing, the housing further comprising: an electrically operated active element, a safety device which is arranged in the circuit for the current supply to the active element and only closes the circuit when the safety device is actuated, a base, wherein the base is designed to receive the container , a lid , wherein the lid is designed to close the first opening of the container , wherein the handle substantially extends over the entire height of the container and has a cavity, wherein a safety element is arranged in the cavity, wherein the safety element is arranged in such a way that it actuates the safety device when the container is closed with the lid . an electrically operated active element, a safety device which is arranged in the circuit for the current supply to the active element and only closes the circuit when the safety device is actuated, a base, wherein the base is designed to receive the container , a lid , wherein the lid is designed to close the first opening of the container , wherein the handle substantially extends over the entire height of the container and has a cavity, wherein a safety element is arranged in the cavity, wherein the safety element is arranged in such a way that it actuates the safety device when the container is closed with the lid .
Valve with a housing , a solenoid which is arranged in the housing , a pin which can be moved by the solenoid , and a piston which is connected to the pin, a second housing part being provided which bears against the housing and partially surrounds the piston , and a seal for sealing the valve, characterized in that the second housing part is composed of metal, in that the second housing part is a deep-drawn part, in that the seal which seals the valve is arranged on its side which faces the housing , in that the second housing part has a radially outwardly projecting edge on its side which faces the housing , in that the seal is arranged on the edge , by the seal surrounding at least one region of the edge , and in that the edge has recesses and the seal penetrates these recesses .