mhurhangee/patent-ind-claim-en huggingface dataset:
A method for enriching a target nucleic acid comprising: providing an endonuclease system having: a clustered regularly interspaced short palindromic repeats (CRISPR) RNA (crRNA) or a derivative thereof, and a CRISPR-associated (Cas) protein or a variant thereof, wherein the crRNA or the derivative thereof contains a target-specific nucleotide region complementary to a region of the target nucleic acid; contacting the target nucleic acid with the endonuclease system to form a complex, wherein the crRNA or the derivative thereof in the complex formed by the CRISPR-Cas endonuclease system is labelled to facilitate separation of the complex, and separating the complex using the label, thereby enriching for the target nucleic acid. providing an endonuclease system having: a clustered regularly interspaced short palindromic repeats (CRISPR) RNA (crRNA) or a derivative thereof, and a CRISPR-associated (Cas) protein or a variant thereof, wherein the crRNA or the derivative thereof contains a target-specific nucleotide region complementary to a region of the target nucleic acid; a clustered regularly interspaced short palindromic repeats (CRISPR) RNA (crRNA) or a derivative thereof, and a CRISPR-associated (Cas) protein or a variant thereof, wherein the crRNA or the derivative thereof contains a target-specific nucleotide region complementary to a region of the target nucleic acid; contacting the target nucleic acid with the endonuclease system to form a complex, wherein the crRNA or the derivative thereof in the complex formed by the CRISPR-Cas endonuclease system is labelled to facilitate separation of the complex, and separating the complex using the label, thereby enriching for the target nucleic acid.
An electrolytic capacitor comprising: a capacitor element ; a bottomed case that houses the capacitor element; a sealing member that seals an opening of the bottomed case; a tab terminal connected to the capacitor element and penetrating through the sealing member; and a resin layer that covers at least part of a main surface of the sealing member, the main surface being disposed outside the bottomed case, wherein: the tab terminal includes a first portion containing a first metal and a second portion containing a second metal, the resin layer is in contact with the first portion and the second portion, and linear expansion coefficient α 1 of the first metal, linear expansion coefficient α 2 of the second metal, and linear expansion coefficient α r of the resin layer satisfy a relation of α 1 < α r < α 2 or α r < α 1 < α 2 . a capacitor element ; a bottomed case that houses the capacitor element; a sealing member that seals an opening of the bottomed case; a tab terminal connected to the capacitor element and penetrating through the sealing member; and a resin layer that covers at least part of a main surface of the sealing member, the main surface being disposed outside the bottomed case, wherein: the tab terminal includes a first portion containing a first metal and a second portion containing a second metal, the resin layer is in contact with the first portion and the second portion, and linear expansion coefficient α 1 of the first metal, linear expansion coefficient α 2 of the second metal, and linear expansion coefficient α r of the resin layer satisfy a relation of α 1 < α r < α 2 or α r < α 1 < α 2 . the tab terminal includes a first portion containing a first metal and a second portion containing a second metal, the resin layer is in contact with the first portion and the second portion, and linear expansion coefficient α 1 of the first metal, linear expansion coefficient α 2 of the second metal, and linear expansion coefficient α r of the resin layer satisfy a relation of α 1 < α r < α 2 or α r < α 1 < α 2 .
Locking cap for a container having a neck , which locking cap is intended to block a stopper in the neck of the container , comprising: - a cage made of plastics material and designed to surround the stopper and the neck and to lock them axially in position relative to one another; - a body made of plastics material and fastened around the cage , the body comprising a central orifice which provides access from the exterior of the cap to the interior of the container via the stopper ; - a capsule designed to close the central orifice , the capsule comprising a flat head for covering the orifice , and fastening tabs caught between the cage and the body ; the locking cap being characterized in that: - each fastening tab has a breakable zone , - the capsule is made from a plastics material which is different from the plastics material of the cage and from the plastics material of the body , the plastics material of the capsule being selected to have a resistance to rupture that is reduced by a dose of gamma ray irradiation which sterilizes the cap . - a cage made of plastics material and designed to surround the stopper and the neck and to lock them axially in position relative to one another; - a body made of plastics material and fastened around the cage , the body comprising a central orifice which provides access from the exterior of the cap to the interior of the container via the stopper ; - a capsule designed to close the central orifice , the capsule comprising a flat head for covering the orifice , and fastening tabs caught between the cage and the body ; - each fastening tab has a breakable zone , - the capsule is made from a plastics material which is different from the plastics material of the cage and from the plastics material of the body , the plastics material of the capsule being selected to have a resistance to rupture that is reduced by a dose of gamma ray irradiation which sterilizes the cap .
A method , comprising: receiving, by a mobile operating server , from a mobile device a request to generate one or more keep-alive messages , the request including information on a destination push server ; generating , by the mobile operating server , the one or more keep-alive messages ; transmitting , by the mobile operating server , the one or more keep-alive messages to the destination push server ; stopping the transmitting when the mobile device is not connected to a network provided by the mobile operating server ; and wherein the transmitting includes transmitting the one or more keep-alive messages periodically to the destination push server . receiving, by a mobile operating server , from a mobile device a request to generate one or more keep-alive messages , the request including information on a destination push server ; generating , by the mobile operating server , the one or more keep-alive messages ; transmitting , by the mobile operating server , the one or more keep-alive messages to the destination push server ; stopping the transmitting when the mobile device is not connected to a network provided by the mobile operating server ; and wherein the transmitting includes transmitting the one or more keep-alive messages periodically to the destination push server .
A tadalafil orally dissolving film, which is prepared by tadalafil, film-forming material, plasticizer, optional correctant, optional colorant and optional aromatic, wherein the film-forming material consisting of components of: (a) pullulan; (b) at least one member selected from a group consisting of salicylic acid, tartaric acid, citric acid, oxalic acid and acetic acid; and (c) at least one member selected from a group consisting of hydroxypropyl cellulose, hydroxypropyl methylcellulose and hydroxyethyl cellulose.
A load cell comprising a spring body formed rotationally symmetrically about a center axis (A) and having an outer support ring , having an upwardly projecting inner force introduction element , and having an annular deformation section which is formed as an annular membrane and via which the support ring and the force introduction element are fixedly connected to one another; and a plurality of strain gauges arranged on a lower side of the membrane for detecting a stretching and/or compressive deformation of the spring body , with the strain gauges being electrically connected to form a Wheatstone bridge or as a part thereof, wherein at least one first strain gauge , in particular two first strain gauges , is/are disposed on a first circle having a first radius (R1) about the center axis (A) of the spring body and at least one second strain gauge , in particular two second strain gauges , is/are disposed on a second circle having a second radius (R2), which is greater than the first radius (R1), about the center axis (A) of the spring body , wherein the mean thickness (D) of the annular membrane in the region of the first strain gauge or gauges is larger than the mean thickness in the region of the second strain gauge or gauges , characterized in that the two first strain gauges are arranged along a first line through the center axis (A) of the spring body and the two second strain gauges are arranged along a second line through the center axis (A) of the spring body , with the two lines being rotated with respect to one another by an angle from 5° to 20°. a spring body formed rotationally symmetrically about a center axis (A) and having an outer support ring , having an upwardly projecting inner force introduction element , and having an annular deformation section which is formed as an annular membrane and via which the support ring and the force introduction element are fixedly connected to one another; and a plurality of strain gauges arranged on a lower side of the membrane for detecting a stretching and/or compressive deformation of the spring body , with the strain gauges being electrically connected to form a Wheatstone bridge or as a part thereof, wherein at least one first strain gauge , in particular two first strain gauges , is/are disposed on a first circle having a first radius (R1) about the center axis (A) of the spring body and at least one second strain gauge , in particular two second strain gauges , is/are disposed on a second circle having a second radius (R2), which is greater than the first radius (R1), about the center axis (A) of the spring body , wherein the mean thickness (D) of the annular membrane in the region of the first strain gauge or gauges is larger than the mean thickness in the region of the second strain gauge or gauges , characterized in that the two first strain gauges are arranged along a first line through the center axis (A) of the spring body and the two second strain gauges are arranged along a second line through the center axis (A) of the spring body , with the two lines being rotated with respect to one another by an angle from 5° to 20°.
Device, preferably a magnetic filter, for separating magnetisable contaminants from flowing fluids, comprising a cylindrical chamber with a fluid inlet for the fluid containing magnetisable particles, a clean fluid outlet for the cleaned fluid and a particle outlet for the magnetisable particles, wherein within the chamber an inner cylinder body is arranged which with the chamber wall forms an annual gap through which the fluid flows, at least one magnet which is arranged outside the annular gap in the direction of flow between the fluid inlet and the clean fluid outlet , a rotatable, helical scraper arranged in the annular gap for transporting magnetisable particles deposited on the wall of the chamber to the particle outlet , an actuator for the helical scraper characterised in that the throughflow of the flowing fluid is brought about by negative pressure or over-pressure, wherein an inlet valve is located upstream of or at the fluid inlet and an outlet valve is provided at the particle outlet , wherein the actuator is designed not to actuate the scraper in normal operation in which the fluid to be cleaned is flowing through the annular gap and to actuate it during a period of filter cleaning.
A heat exchanger, comprising: a first header ; a second header ; and a plurality of fins each disposed between adjacent tubes , wherein the heat exchanger has a bent portion between the first and second headers such that the heat exchanger is divided into first and second heat exchanger portions which are located at two sides of the bent portion, respectively, and wherein a heat transfer coefficient of the second heat exchanger portion is greater than that of the first heat exchanger portion , wherein each fin is divided into a first fin portion in the first heat exchanger portion and a second fin portion in the second heat exchanger portion , and a heat transfer coefficient of the second fin portions is greater than that of the first fin portions , characterized in that the heat exchanger comprises a plurality of tubes spaced apart from each other and each connected between the first and second headers in fluid communication therewith; wherein each of the first and second fin portions is formed with louvers, in which a louver angle of the louvers in each second fin portion is greater than that of the louvers in each first fin portion, and/or each of the first and second fin portions is formed with louvers , in which a louver length (Lh) of the louvers in each second fin portion is greater than that of the louvers in each first fin portion . a first header ; a second header ; and a plurality of fins each disposed between adjacent tubes , wherein the heat exchanger has a bent portion between the first and second headers such that the heat exchanger is divided into first and second heat exchanger portions which are located at two sides of the bent portion, respectively, and wherein a heat transfer coefficient of the second heat exchanger portion is greater than that of the first heat exchanger portion , wherein each fin is divided into a first fin portion in the first heat exchanger portion and a second fin portion in the second heat exchanger portion , and a heat transfer coefficient of the second fin portions is greater than that of the first fin portions , characterized in that the heat exchanger comprises a plurality of tubes spaced apart from each other and each connected between the first and second headers in fluid communication therewith; wherein each of the first and second fin portions is formed with louvers, in which a louver angle of the louvers in each second fin portion is greater than that of the louvers in each first fin portion, and/or each of the first and second fin portions is formed with louvers , in which a louver length (Lh) of the louvers in each second fin portion is greater than that of the louvers in each first fin portion .
A method for fabricating a semiconductor device, comprising: providing (S101) a plurality of fins on a surface of the semiconductor substrate ; forming (S102) an isolation flowable layer covering the plurality of fins over the semiconductor substrate ; performing (S103) a first annealing process to turn the isolation flowable layer into an isolation film ; and forming (S109) first well regions and second well regions in the fins and the semiconductor substrate , the second well regions being at two sides of the first well regions and contacting with the first well regions , the first well regions having a first type of well ions, the second well regions having a second type of well ions, and the first type being opposite to the second type, characterized in that the first annealing process is performed before forming the first well regions and the second well regions , wherein an environment of the first annealing process includes oxygen, ozone and water vapor, a temperature of the first annealing process is in a range of 350°C-750°C, and a time duration of the first annealing process is in a range of 25 mins-35 mins. providing (S101) a plurality of fins on a surface of the semiconductor substrate ; forming (S102) an isolation flowable layer covering the plurality of fins over the semiconductor substrate ; performing (S103) a first annealing process to turn the isolation flowable layer into an isolation film ; and forming (S109) first well regions and second well regions in the fins and the semiconductor substrate , the second well regions being at two sides of the first well regions and contacting with the first well regions , the first well regions having a first type of well ions, the second well regions having a second type of well ions, and the first type being opposite to the second type,
Use of a composition comprising an activator of mTOR in vitro for sperm quality and function enhancing.
A Hall-type travel limit deviation self-resetting encoder for a garage door machine, comprising a nylon worm gear and a driving motor for driving the nylon worm gear to rotate; characterized by further comprising: a motor rotation counting limit mechanism adapted for performing rotation counting limit on a rotor shaft of the driving motor , and a worm gear counting calibration mechanism adapted for calibrating the travel limit deviation of the driving motor; the worm gear counting calibration mechanism comprises a worm gear magnet mounted on the nylon worm gear and a worm gear position Hall element adapted to detect the worm gear magnet and in that, the motor rotation counting limit mechanism comprises a motor magnet mounted on the rotor shaft of the driving motor and a motor position Hall element adapted to cooperate with the motor magnet . a motor rotation counting limit mechanism adapted for performing rotation counting limit on a rotor shaft of the driving motor , and a worm gear counting calibration mechanism adapted for calibrating the travel limit deviation of the driving motor; the worm gear counting calibration mechanism comprises a worm gear magnet mounted on the nylon worm gear and a worm gear position Hall element adapted to detect the worm gear magnet and in that, the motor rotation counting limit mechanism comprises a motor magnet mounted on the rotor shaft of the driving motor and a motor position Hall element adapted to cooperate with the motor magnet .
A surgical device, comprising: a biocompatible tubular member configured to be implanted in a bone of a patient, the tubular member having a solid sidewall defining an inner lumen extending through the tubular member such that blood can flow into the inner lumen through a first open end of the inner lumen and out of the inner lumen through a second open end of the inner lumen , and the tubular member having an anti-coagulation agent on the solid sidewall; characterized in that the inner lumen has a plug removably disposed therein that occludes the inner lumen such that the blood cannot flow out of the inner lumen through the second open end of the inner lumen until the plug is removed from the inner lumen , the plug being configured to be implanted in the patient with the tubular member . a biocompatible tubular member configured to be implanted in a bone of a patient, the tubular member having a solid sidewall defining an inner lumen extending through the tubular member such that blood can flow into the inner lumen through a first open end of the inner lumen and out of the inner lumen through a second open end of the inner lumen , and the tubular member having an anti-coagulation agent on the solid sidewall; characterized in that the inner lumen has a plug removably disposed therein that occludes the inner lumen such that the blood cannot flow out of the inner lumen through the second open end of the inner lumen until the plug is removed from the inner lumen , the plug being configured to be implanted in the patient with the tubular member .
A pharmaceutical composition comprising an IL-13Rα2 peptide; an EphA2 peptide; and only a single survivin peptide comprising the amino sequence of SEQ ID N0:9; and a Tetanus toxoid epitope, wherein said composition is emulsified by Montanide ISA-51, for use in a method of treating, preventing, or managing brain cancer in a subject in need thereof, wherein the pharmaceutical composition is administered to the subject subcutaneously, and further wherein the pharmaceutical composition is co-administered with bevacizumab.
A sun-protection roller blind for a motor vehicle, comprising two guide rails , a flat roller blind body and two guide bands made of plastic, which extend along two edges of the roller blind body and are welded to the roller blind body , the guide bands being received in the guide rails , the guide rails each having a C-shaped cross section with a short leg arranged toward the center of the vehicle and a leg arranged toward the outside of the vehicle, the short leg arranged toward the center of the vehicle each being arranged at a lower level than the leg located on the outside of the vehicle, so that the inside of the short leg arranged toward the center of the vehicle is offset with respect to the inside of the leg located on the outside of the vehicle, the edges of the roller blind body being welded to the side of the guide bands that faces away from the vehicle center and resting against the outer leg on the inside of the guide rails , the weld seam extending over less than 50% of the width of the guide bands , characterized in that the guide bands have a thickness in the range of from 250 μm to 500 μm.
A compound semiconductor represented by the following Chemical Formula 1: [Chemical Formula 1] Nd x S y Co 4 Sb 12-z Q z wherein, in Chemical Formula 1, Q is one or more selected from the group consisting of O, Se, and Te, 0<x<0.2, 0<y≤1, and 0<z<12.
Refrigerator and/or freezer having a thermally insulated appliance body that encloses an interior space, wherein a removal opening is provided on the front side of the appliance body in order to be able to introduce goods into the interior space and remove them therefrom, wherein a thermally insulated door is provided for reversibly closing the removal opening, wherein the appliance a projection surface surrounding the door , which projection surface is preferably at least partially visible from the front, and in that the appliance further has a light source that is at least partially concealed from the front to illuminate the projection surface, characterised in that the projection surface is formed by an area on the front of the appliance body that frames the removal opening.
A method of decreasing aldehyde content in a polymeric material, the method comprises the step of contacting the polymeric material with a compound (A) which includes: (I) a first fragment which comprises a moiety and a moiety NH (B) wherein the carbon atom of moiety (A) and the nitrogen atom of moiety (B) are separated by at least one and not more than two atoms; (II) a second fragment which comprises a moiety and a moiety NH (B) wherein the carbon atom of moiety (A) and the nitrogen atom of moiety (B) are separated by at least one and not more than two atoms; and (III) a third fragment which comprises a moiety and a moiety NH (B). (I) a first fragment which comprises a moiety and a moiety NH (B) wherein the carbon atom of moiety (A) and the nitrogen atom of moiety (B) are separated by at least one and not more than two atoms; (II) a second fragment which comprises a moiety and a moiety NH (B) wherein the carbon atom of moiety (A) and the nitrogen atom of moiety (B) are separated by at least one and not more than two atoms; and (III) a third fragment which comprises a moiety and a moiety NH (B).