A compound represented by structural formula I: or a pharmaceutically acceptable salt thereof, wherein: X represents ZC 6-10 aryl, said aryl optionally substituted with 1 to 3 groups of R a ; Z represents a bond, -(CH2) n -, -(C(O)NH-, -CH(OH)-, -C(CH 3 )OH-, -(CH 2 ) n NH-, or-(CH 2 ) n NCH 3 -; R 1 represents C 1-6 alkyl, (CH 2 ) 1-4 OR or C 1-4 haloalkyl, wherein said alkyl is optionally substituted with 1 to 3 groups of R a ; R 2 represents halo, C 1-6 alkyl, (CH 2 ) n OR, C 1-4 haloalkyl, C(O)OR, C=O, (CH 2 ) n C 3-10 heterocyclyl, O-(CH 2 ) n C 4-10 heterocyclyl, C(O)NH(CH 2 CF 3 ), NR 2 , NHSO 2 R, C(O)R, C(O)-N-linked morpholinyl, NHC(O)CH 3 , (CH 2 ) n C(CF 3 )OH, CF 2 CH 2 OH, said alkyl and heterocyclyl optionally substituted with 1 to 3 groups of R a , R 3 and R 3a independently represent hydrogen, C 1-6 alkyl, or C 3-6 cycloalkyl, or R 3 and R 3a can combine with the carbon atom to which they are attached to form a C 3-6 cycloalkyl, or C 4-10 heterocycloalkyl, said alkyl, cycloalkyl, and heterocycloalkyl optionally substituted with 1 to 3 groups of R a , or R 3 or R 3a can combine with X and the carbon atom to which they are attached to form a C 6-10 aryl, said aryl optionally substituted with 1 to 3 groups of R a , R represents hydrogen or C 1-6 alkyl, said alkyl optionally substituted with 1 to 3 groups of R a , R a is selected from the group consisting of halo, CN, C 1-6 alkyl, (CH 2 ) n OR, (CH 2 ) n C 1-4 haloalkyl, O-C 1-4 haloalkyl, SCF 3 , SF 5 , C 6-10 aryl, C(O)N(CH 3 ) 2 , =NOH, NHOH, SO 2 R, NR 2 , OC(O)CH 3 , NHC(O)CH 3 , OCH 2 C 6-10 aryl, and C 3-6 cycloalkyl, said cycloalkyl optionally substituted with 1 to 3 groups selected from C 1-6 alkyl and C 1-4 haloalkyl; n represents 0, 1, 2, 3, or 4. X represents ZC 6-10 aryl, said aryl optionally substituted with 1 to 3 groups of R a ; Z represents a bond, -(CH2) n -, -(C(O)NH-, -CH(OH)-, -C(CH 3 )OH-, -(CH 2 ) n NH-, or-(CH 2 ) n NCH 3 -; R 1 represents C 1-6 alkyl, (CH 2 ) 1-4 OR or C 1-4 haloalkyl, wherein said alkyl is optionally substituted with 1 to 3 groups of R a ; R 2 represents halo, C 1-6 alkyl, (CH 2 ) n OR, C 1-4 haloalkyl, C(O)OR, C=O, (CH 2 ) n C 3-10 heterocyclyl, O-(CH 2 ) n C 4-10 heterocyclyl, C(O)NH(CH 2 CF 3 ), NR 2 , NHSO 2 R, C(O)R, C(O)-N-linked morpholinyl, NHC(O)CH 3 , (CH 2 ) n C(CF 3 )OH, CF 2 CH 2 OH, said alkyl and heterocyclyl optionally substituted with 1 to 3 groups of R a , R 3 and R 3a independently represent hydrogen, C 1-6 alkyl, or C 3-6 cycloalkyl, or R 3 and R 3a can combine with the carbon atom to which they are attached to form a C 3-6 cycloalkyl, or C 4-10 heterocycloalkyl, said alkyl, cycloalkyl, and heterocycloalkyl optionally substituted with 1 to 3 groups of R a , or R 3 or R 3a can combine with X and the carbon atom to which they are attached to form a C 6-10 aryl, said aryl optionally substituted with 1 to 3 groups of R a , R represents hydrogen or C 1-6 alkyl, said alkyl optionally substituted with 1 to 3 groups of R a , R a is selected from the group consisting of halo, CN, C 1-6 alkyl, (CH 2 ) n OR, (CH 2 ) n C 1-4 haloalkyl, O-C 1-4 haloalkyl, SCF 3 , SF 5 , C 6-10 aryl, C(O)N(CH 3 ) 2 , =NOH, NHOH, SO 2 R, NR 2 , OC(O)CH 3 , NHC(O)CH 3 , OCH 2 C 6-10 aryl, and C 3-6 cycloalkyl, said cycloalkyl optionally substituted with 1 to 3 groups selected from C 1-6 alkyl and C 1-4 haloalkyl; n represents 0, 1, 2, 3, or 4. <EOS>