mhurhangee/patent-ind-claim-en huggingface dataset:
A system for the separation of a biological fluid into its components, wherein the system comprises: a centrifugal separating chamber rotatable about an axis of rotation (AR) and having walls that define a hollow interior , a top end , a bottom end and an axial opening positioned at said top end ; an axially movable member contained within said chamber which, along with said walls , defines a separation space of variable volume, within said chamber ; a plurality of valves wherein each valve is in selective fluid connection with one of a plurality of tubes ; at least one container fluidly connected to said plurality of tubes whereby said chamber and said at least one container are in selective fluid communication; a length of tubing for establishing fluid communication between said chamber and said plurality of valves , said tubing including a portion which forms at least a part of a pump for fluid pumping within the tubing ; and a pulse dampener positioned along said tubing between said chamber and the position for said portion ; characterized in that : a valve of the plurality of valves in the flow path between a container of said at least one container and the separation space is adjustable to open a path between the container and the separation space , and wherein the pump is activatable to promote movement of the biological fluid from the container to the separation space as well as movement of the axially movable member towards the bottom end of the separating chamber . a centrifugal separating chamber rotatable about an axis of rotation (AR) and having walls that define a hollow interior , a top end , a bottom end and an axial opening positioned at said top end ; an axially movable member contained within said chamber which, along with said walls , defines a separation space of variable volume, within said chamber ; a plurality of valves wherein each valve is in selective fluid connection with one of a plurality of tubes ; at least one container fluidly connected to said plurality of tubes whereby said chamber and said at least one container are in selective fluid communication; a length of tubing for establishing fluid communication between said chamber and said plurality of valves , said tubing including a portion which forms at least a part of a pump for fluid pumping within the tubing ; and a pulse dampener positioned along said tubing between said chamber and the position for said portion ; characterized in that : a valve of the plurality of valves in the flow path between a container of said at least one container and the separation space is adjustable to open a path between the container and the separation space , and wherein the pump is activatable to promote movement of the biological fluid from the container to the separation space as well as movement of the axially movable member towards the bottom end of the separating chamber .
A non-therapeutic use of a composition comprising a material inhibiting the expression or activity of JAB-1 (Jun activator binding-1) for moisturizing skin or strengthening skin barrier function by promoting differentiation of skin cells, wherein the material inhibiting the expression or activity of JAB-1 is an RNA nucleic acid molecule which is at least one of siRNA, shRNA, and miRNA which bind to the mRNA of JAB-1, and wherein the material inhibiting the expression or activity of JAB-1 is formulated in a form of a composition which is a cosmetic composition or a health food composition. wherein the material inhibiting the expression or activity of JAB-1 is an RNA nucleic acid molecule which is at least one of siRNA, shRNA, and miRNA which bind to the mRNA of JAB-1, and wherein the material inhibiting the expression or activity of JAB-1 is formulated in a form of a composition which is a cosmetic composition or a health food composition.
A method for enrichment of target DNA with high GC content, comprising the following steps: (a) designing single-stranded oligonucleotide probes against specific flanking sequences of the target DNA with high GC content, and capturing the target DNA from genome DNA by target sequence capture technology; (b) amplifying the captured target DNA with high GC content using multiple displacement amplification so as to obtain amplification product; (c) subjecting the amplification product to enzyme digestion to remove branched DNA intermediates, so as to obtain digested product; (d) purifying DNA fragment with a length equal to or larger than 2kb, so as to obtain enriched target DNA with high GC content. (a) designing single-stranded oligonucleotide probes against specific flanking sequences of the target DNA with high GC content, and capturing the target DNA from genome DNA by target sequence capture technology; (b) amplifying the captured target DNA with high GC content using multiple displacement amplification so as to obtain amplification product; (c) subjecting the amplification product to enzyme digestion to remove branched DNA intermediates, so as to obtain digested product; (d) purifying DNA fragment with a length equal to or larger than 2kb, so as to obtain enriched target DNA with high GC content.
Battery cell connection element having a main body in the form of a fluid conduit element made from an electrically conductive material with a longitudinal axis (L), which main body is preferably closed at its two ends , in particular in a fluid-tight manner, and has a peripherally substantially closed casing wall, in which casing wall at least two apertures , preferably punch-puts, are arranged on the same side of the main body , which apertures are arranged next to one another and offset in the direction of the longitudinal axis (L), characterized in that the main body is configured to be substantially flat in some sections, at least on its side opposite the apertures , so that flat sections of the main body are in alignment with the apertures in a direction perpendicular to the longitudinal axis (L), in which preferably the main body has two substantially flat side walls arranged parallel to one another in some sections, in one of which the apertures are arranged.
A capacitive sensor device with continuous self-test, the sensor device comprising - at least two inertial channels (CH1, CH2, CH3, CH4); - at least two capacitive elements (100, 102; 300a, 300b, 302a, 302b; 501) configured to detect said at least two inertial channels (CH1, CH2, CH3, CH4); and - a multiplexer circuitry configured to temporally multiplex said at least two inertial channels, characterized in that the capacitive sensor device is configured such that at least two self-test tones (STF1, STF2, STF3) with distinctive fundamental frequencies are fed into at least one capacitive element (100, 102; 300a, 300b, 302a, 302b; 501) of at least one of the at least two inertial channels (CH1, CH2, CH3, CH4) during different time periods while reading inertial data from a capacitive element (100, 102; 300a, 300b, 302a, 302b; 501) of another of the at least two inertial channels (CH1, CH2, CH3, CH4). - at least two inertial channels (CH1, CH2, CH3, CH4); - at least two capacitive elements (100, 102; 300a, 300b, 302a, 302b; 501) configured to detect said at least two inertial channels (CH1, CH2, CH3, CH4); and - a multiplexer circuitry configured to temporally multiplex said at least two inertial channels,
A system comprising: one or more sensors configured to detect one or more parameters with respect to movement of a user, a cardiac activity of the user, audio associated with the user, or a combination thereof during a sleep session of the user; memory storing machine-readable instructions; and a control system including one or more processors configured to execute the machine-readable instructions to: process the one or more parameters to determine a sleep status of the user during the sleep session, the sleep status being at least one of awake, asleep, or a sleep stage; process the one or more parameters to determine the occurrence of sleep disordered breathing events occurring during the sleep session; disregard one or more sleep disordered sleep disordered breathing events in response to the sleep status being determined as awake during the one or more sleep disordered breathing events; and calculate an apnea-hypopnea index for the user during the sleep session based, at least in part, on the remaining sleep disordered breathing events occurring during the sleep session. one or more sensors configured to detect one or more parameters with respect to movement of a user, a cardiac activity of the user, audio associated with the user, or a combination thereof during a sleep session of the user; memory storing machine-readable instructions; and a control system including one or more processors configured to execute the machine-readable instructions to: process the one or more parameters to determine a sleep status of the user during the sleep session, the sleep status being at least one of awake, asleep, or a sleep stage; process the one or more parameters to determine the occurrence of sleep disordered breathing events occurring during the sleep session; disregard one or more sleep disordered sleep disordered breathing events in response to the sleep status being determined as awake during the one or more sleep disordered breathing events; and calculate an apnea-hypopnea index for the user during the sleep session based, at least in part, on the remaining sleep disordered breathing events occurring during the sleep session. process the one or more parameters to determine a sleep status of the user during the sleep session, the sleep status being at least one of awake, asleep, or a sleep stage; process the one or more parameters to determine the occurrence of sleep disordered breathing events occurring during the sleep session; disregard one or more sleep disordered sleep disordered breathing events in response to the sleep status being determined as awake during the one or more sleep disordered breathing events; and calculate an apnea-hypopnea index for the user during the sleep session based, at least in part, on the remaining sleep disordered breathing events occurring during the sleep session.
A method for producing a connection between an electrical conductor and a current-carrying element, in which a one-piece cable lug made of metal is used, which has a transition element in the form of a web, which consists of two flat parts connected to each other by means of a ramp , which on one end has a three-dimensional contact part for the connection to the end of the electrical conductor and on its other end has a contact end for the connection of the current-carrying element, wherein the cable lug is used with the contact part designed as a pot-like container having a base , which contact part is closed at its base , wherein the method comprises the following steps: - the end of the conductor is first stripped and inserted into the container of the cable lug , wherein its end face is guided to the base of the container , - the cable lug is then connected to the stripped conductor end by crimping the wall of the container and - finally the end face of the conductor is welded to the base of the container by friction stir welding. - the end of the conductor is first stripped and inserted into the container of the cable lug , wherein its end face is guided to the base of the container , - the cable lug is then connected to the stripped conductor end by crimping the wall of the container and - finally the end face of the conductor is welded to the base of the container by friction stir welding.
A display device comprising: a display panel ; a vapor chamber positioned behind the display panel ; a board , which is positioned behind the vapor chamber and is coupled to the vapor chamber ; and an adhesive member (a, b) disposed between the display panel and the vapor chamber so as to be coupled thereto, wherein the vapor chamber comprises: a first plate , which defines a front surface thereof and faces the display panel ; a second plate , which defines a rear surface thereof and is coupled to the first plate ; and fluid (W) flowing in a space (S) defined between the first plate and the second plate , and characterized in that the first plate comprises a coupler , which is depressed rearwards from the first plate and to which the adhesive member (a, b) is coupled. a display panel ; a vapor chamber positioned behind the display panel ; a board , which is positioned behind the vapor chamber and is coupled to the vapor chamber ; and an adhesive member (a, b) disposed between the display panel and the vapor chamber so as to be coupled thereto, wherein the vapor chamber comprises: a first plate , which defines a front surface thereof and faces the display panel ; a second plate , which defines a rear surface thereof and is coupled to the first plate ; and fluid (W) flowing in a space (S) defined between the first plate and the second plate , and characterized in that the first plate comprises a coupler , which is depressed rearwards from the first plate and to which the adhesive member (a, b) is coupled. a first plate , which defines a front surface thereof and faces the display panel ; a second plate , which defines a rear surface thereof and is coupled to the first plate ; and fluid (W) flowing in a space (S) defined between the first plate and the second plate , and characterized in that the first plate comprises a coupler , which is depressed rearwards from the first plate and to which the adhesive member (a, b) is coupled.
A combined continuous casting and endless rolling plant for a metal strip, comprising - a continuous casting line for casting a slab; - a first rolling mill for roughing the slab and for obtaining a transfer bar; - a second rolling mill for finishing the transfer bar and for obtaining a strip; - accumulation means of the strip comprising at least one first reel dimensioned to wind and unwind a coil weighing from 80 to 250 metric tons and/or up to 6 meters in diameter, named mega coil; characterized in that there are provided - a third rolling mill , comprising at least two rolling stands , for further reducing the thickness of the strip; - first cutting means , arranged between said third rolling mill and said accumulation means , configured to cut the strip after the mega coil has been wound on the at least one first reel ; - at least one second reel for winding portions of strip, unwound from said accumulation means , up to a predetermined weight limit or coil diameter limit; - second cutting means , arranged between said accumulation means and said at least one second reel , adapted to cut the strip whenever a portion of strip wound on the at least one second reel reaches said predetermined weight limit or coil diameter limit. - a continuous casting line for casting a slab; - a first rolling mill for roughing the slab and for obtaining a transfer bar; - a second rolling mill for finishing the transfer bar and for obtaining a strip; - accumulation means of the strip comprising at least one first reel dimensioned to wind and unwind a coil weighing from 80 to 250 metric tons and/or up to 6 meters in diameter, named mega coil; characterized in that there are provided - a third rolling mill , comprising at least two rolling stands , for further reducing the thickness of the strip; - first cutting means , arranged between said third rolling mill and said accumulation means , configured to cut the strip after the mega coil has been wound on the at least one first reel ; - at least one second reel for winding portions of strip, unwound from said accumulation means , up to a predetermined weight limit or coil diameter limit; - second cutting means , arranged between said accumulation means and said at least one second reel , adapted to cut the strip whenever a portion of strip wound on the at least one second reel reaches said predetermined weight limit or coil diameter limit.
A robot cleaner comprising: a main body configured to form an outer shape; a water tank configured to contain water; a pair of rotary mop configured to move the main body while rotating in contact with a floor; a drive motor configured to rotate the pair of rotary mop ; a pump configured to be connected to the water tank and drive a nozzle that inject the water to the rotary mop ; and a controller configured to determine whether the water in the water tank is insufficient by reading the output current of the drive motor to determine the water content of the rotary mop when the pair of rotary mops rotate. a main body configured to form an outer shape; a water tank configured to contain water; a pair of rotary mop configured to move the main body while rotating in contact with a floor; a drive motor configured to rotate the pair of rotary mop ; a pump configured to be connected to the water tank and drive a nozzle that inject the water to the rotary mop ; and a controller configured to determine whether the water in the water tank is insufficient by reading the output current of the drive motor to determine the water content of the rotary mop when the pair of rotary mops rotate.
A liposome composition comprising: a liposome which contains a nucleic acid analog anticancer agent and in which a content ratio of a lysophospholipid contained in a lipid forming the liposome with respect to a total amount of phospholipids other than the lysophospholipid contained in the lipid forming the liposome is 0.01 mol% to 5 mol% and a nucleic acid analog anticancer agent / lipid ratio is 2 mass% to 10 mass%, wherein the nucleic acid analog anticancer agent is gemcitabine or a salt thereof, the liposome composition is no liposome composition having a gemcitabine concentration of 0.68 mg/ml, a particle size of 73 nm, and an inner water phase/out water phase osmotic pressure ratio of 3.6-fold, and the liposome composition is no liposome composition having a gemcitabine hydrochloride concentration of 0.71 mg/ml, a particle size of 75.7 nm, an inner water phase osmotic pressure of 1039 mOsm/l, and an outer water phase osmotic pressure of 285 mOsm/l, with the osmotic pressure of the inner water phase being 3.6-fold relative to that of the outer water phase. a liposome which contains a nucleic acid analog anticancer agent and in which a content ratio of a lysophospholipid contained in a lipid forming the liposome with respect to a total amount of phospholipids other than the lysophospholipid contained in the lipid forming the liposome is 0.01 mol% to 5 mol% and a nucleic acid analog anticancer agent / lipid ratio is 2 mass% to 10 mass%, wherein the nucleic acid analog anticancer agent is gemcitabine or a salt thereof, the liposome composition is no liposome composition having a gemcitabine concentration of 0.68 mg/ml, a particle size of 73 nm, and an inner water phase/out water phase osmotic pressure ratio of 3.6-fold, and the liposome composition is no liposome composition having a gemcitabine hydrochloride concentration of 0.71 mg/ml, a particle size of 75.7 nm, an inner water phase osmotic pressure of 1039 mOsm/l, and an outer water phase osmotic pressure of 285 mOsm/l, with the osmotic pressure of the inner water phase being 3.6-fold relative to that of the outer water phase.
A variant Cas9 protein with reduced RuvC cleavage activity relative to a corresponding wild type Cas9 protein, the variant Cas9 protein comprising: a RuvC domain, an HNH domain, and a disrupted RuvC/HNH linker region that reduces the RuvC cleavage activity of the variant Cas9 protein relative to the RuvC cleavage activity of the corresponding wild type Cas9 protein, wherein the RuvC/HNH linker region includes amino acids within amino acids 915-937 of the amino acid sequence set forth in SEQ ID NO: 2, or a corresponding region in another Cas9 protein, and wherein the variant Cas9 protein is capable of binding a target nucleic acid. a RuvC domain, an HNH domain, and a disrupted RuvC/HNH linker region that reduces the RuvC cleavage activity of the variant Cas9 protein relative to the RuvC cleavage activity of the corresponding wild type Cas9 protein, wherein the RuvC/HNH linker region includes amino acids within amino acids 915-937 of the amino acid sequence set forth in SEQ ID NO: 2, or a corresponding region in another Cas9 protein, and wherein the variant Cas9 protein is capable of binding a target nucleic acid.
A method for growing a single crystal silicon ingot in a continuous Czochralski process, the method comprising: adding a charge of polycrystalline silicon to a crucible assembly, the crucible assembly comprising a weir and a sidewall that define an outer melt zone between the weir and the sidewall; adding one or more plates to the outer melt zone, the one or more plates each including one or more openings that extend through the plate to allow silicon to enter the melt; forming a melt of silicon in the crucible assembly; contacting a surface of the melt with a seed crystal; withdrawing a single crystal silicon ingot from the melt; and adding solid polycrystalline silicon feedstock to the outer melt zone while withdrawing the single crystal silicon ingot to replenish the melt, the one or more plates at least partially covering the melt in the outer melt zone while adding solid polycrystalline silicon feedstock to the outer melt zone, wherein the polycrystalline silicon melts and falls through the one or more openings that extend through the one or more plates and enters the melt. adding a charge of polycrystalline silicon to a crucible assembly, the crucible assembly comprising a weir and a sidewall that define an outer melt zone between the weir and the sidewall; adding one or more plates to the outer melt zone, the one or more plates each including one or more openings that extend through the plate to allow silicon to enter the melt; forming a melt of silicon in the crucible assembly; contacting a surface of the melt with a seed crystal; withdrawing a single crystal silicon ingot from the melt; and adding solid polycrystalline silicon feedstock to the outer melt zone while withdrawing the single crystal silicon ingot to replenish the melt, the one or more plates at least partially covering the melt in the outer melt zone while adding solid polycrystalline silicon feedstock to the outer melt zone, wherein the polycrystalline silicon melts and falls through the one or more openings that extend through the one or more plates and enters the melt.