mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein: A is selected from C 6 -C 14 -aryl, 5- to 14-membered heteroaryl and 3- to 14-membered heterocyclyl; B is (i) C 6 -C 14 -aryl; and L 1 is -O-; or (ii) 5- to 14-membered heteroaryl; and L 1 is a covalent bond or -O-; m is 0, n is 0 or 1 and X is CR 8 ; or m is 1, n is 1 or 2 and X is CR 8 or N; R 1 , R 2 , and R 3 are independently selected from hydrogen and C 1-6 -alkyl; R 4 , R 5 , R 6 and R 7 are independently selected from hydrogen, halogen, cyano, hydroxy, C 1-6 -alkoxy, halo-C 1-6 -alkoxy, amino-C 1-6 -alkoxy, C 1-6 -alkyl, halo-C 1-6 -alkyl, hydroxy-C 1-6 -alkyl, C 1-6 -alkylsulfonyl, SFs, carbamoyl, C 3-10 -cycloalkyl-C 1-6 -alkoxy-, C 1-6 -alkyl-NH-C(O)-, C 1-6 -alkyl-C(O)-NH-, and C 3-10 -cycloalkyl, wherein each C 3-10 -cycloalkyl is optionally substituted with 1-2 substituents selected from C 1-6 -alkyl and halo-C 1-6 -alkyl; and R 8 is selected from hydrogen, halogen, hydroxy, halo-C 1-6 -alkyl, and C 1-6 -alkyl. A is selected from C 6 -C 14 -aryl, 5- to 14-membered heteroaryl and 3- to 14-membered heterocyclyl; B is (i) C 6 -C 14 -aryl; and L 1 is -O-; or (ii) 5- to 14-membered heteroaryl; and L 1 is a covalent bond or -O-; (i) C 6 -C 14 -aryl; and L 1 is -O-; or (ii) 5- to 14-membered heteroaryl; and L 1 is a covalent bond or -O-; m is 0, n is 0 or 1 and X is CR 8 ; or m is 1, n is 1 or 2 and X is CR 8 or N; R 1 , R 2 , and R 3 are independently selected from hydrogen and C 1-6 -alkyl; R 4 , R 5 , R 6 and R 7 are independently selected from hydrogen, halogen, cyano, hydroxy, C 1-6 -alkoxy, halo-C 1-6 -alkoxy, amino-C 1-6 -alkoxy, C 1-6 -alkyl, halo-C 1-6 -alkyl, hydroxy-C 1-6 -alkyl, C 1-6 -alkylsulfonyl, SFs, carbamoyl, C 3-10 -cycloalkyl-C 1-6 -alkoxy-, C 1-6 -alkyl-NH-C(O)-, C 1-6 -alkyl-C(O)-NH-, and C 3-10 -cycloalkyl, wherein each C 3-10 -cycloalkyl is optionally substituted with 1-2 substituents selected from C 1-6 -alkyl and halo-C 1-6 -alkyl; and R 8 is selected from hydrogen, halogen, hydroxy, halo-C 1-6 -alkyl, and C 1-6 -alkyl.
A delivery system for delivering an expandable implant (70; 1010) to a body location, the delivery system comprising: an elongate deflectable delivery component configured to at least partially retain the expandable implant (70; 1010), the elongate deflectable delivery component configured to bend to assist in steering the delivery system to the body location; and a handle comprising: a rotatable deflection actuator configured to cause desired bending of the deflectable delivery component ; threading on an outer surface of the handle ; and a rotatable retraction actuator configured to mate with the threading , the rotatable retraction actuator being operably connected to the elongate deflectable delivery component ; wherein rotation of the rotatable retraction actuator causes the rotatable retraction actuator and the rotatable deflection actuator to translate proximally along the threading , thereby translating the elongate deflectable delivery component proximally to at least partially release the expandable implant (70; 1010). an elongate deflectable delivery component configured to at least partially retain the expandable implant (70; 1010), the elongate deflectable delivery component configured to bend to assist in steering the delivery system to the body location; and a handle comprising: a rotatable deflection actuator configured to cause desired bending of the deflectable delivery component ; threading on an outer surface of the handle ; and a rotatable retraction actuator configured to mate with the threading , the rotatable retraction actuator being operably connected to the elongate deflectable delivery component ; wherein rotation of the rotatable retraction actuator causes the rotatable retraction actuator and the rotatable deflection actuator to translate proximally along the threading , thereby translating the elongate deflectable delivery component proximally to at least partially release the expandable implant (70; 1010). a rotatable deflection actuator configured to cause desired bending of the deflectable delivery component ; threading on an outer surface of the handle ; and a rotatable retraction actuator configured to mate with the threading , the rotatable retraction actuator being operably connected to the elongate deflectable delivery component ; wherein rotation of the rotatable retraction actuator causes the rotatable retraction actuator and the rotatable deflection actuator to translate proximally along the threading , thereby translating the elongate deflectable delivery component proximally to at least partially release the expandable implant (70; 1010).
A method for generating a Variable Coding and Modulation, VCM, or Adaptive Coding and Modulation, ACM, signal comprising a plurality of frames (PLFRAME), each frame (PLFRAME) comprising a payload (FECFRAME) corresponding to a coded block generated by coding user bits in accordance with a chosen FEC scheme, wherein the payload (FECFRAME) is transformed into at least one symbol block (XFECFRAME) of a modulated LDPC code and wherein the length of said payload (FECFRAME) is equal to 16200 bits or 64800 bits, characterized in that said frame (PLFRAME) has a constant length in terms of transmitted modulation symbols and in terms of time duration and comprises a sequence of n symbol blocks (XFECFRAME), where n is the number of bits per symbol of a modulation scheme adopted by said at least one symbol block (XFECFRAME), said time length of said frame (PLFRAME) being independent of the modulation scheme adopted by said at least one symbol block (XFECFRAME).
An image processing apparatus for restoring a texture component of an input image comprising: an input unit configured to receive an input image; a memory storing information on at least one random patch; and at least one processor configured to: obtain a plurality of random patches based on the information on the at least one random patch and weights, and obtain an output image by applying, to a pixel block included in the input image, the plurality of random patches to which the weights are respectively applied, wherein the weights are obtained based on correlations between the pixel block and each of the plurality of random patches. an input unit configured to receive an input image; a memory storing information on at least one random patch; and at least one processor configured to: obtain a plurality of random patches based on the information on the at least one random patch and weights, and obtain an output image by applying, to a pixel block included in the input image, the plurality of random patches to which the weights are respectively applied, wherein the weights are obtained based on correlations between the pixel block and each of the plurality of random patches. obtain a plurality of random patches based on the information on the at least one random patch and weights, and obtain an output image by applying, to a pixel block included in the input image, the plurality of random patches to which the weights are respectively applied, wherein the weights are obtained based on correlations between the pixel block and each of the plurality of random patches.
A two-stage method for cleaning a particulate filter said method comprising; - a first stage imposing the particulate filter to a structural resonant frequency whilst under increased air pressure, wherein said air pressure is increased in the direction of the clean part of said filter; and - a second stage imposing the particulate filter to an air flow in the direction of the unclean part of said filter . characterized in that there is no flow of air through the particulate filter in the first stage, and the air pressure in the filter is increased to pressure of about and between 4,5 bar to 6,0 bar. - a first stage imposing the particulate filter to a structural resonant frequency whilst under increased air pressure, wherein said air pressure is increased in the direction of the clean part of said filter; and - a second stage imposing the particulate filter to an air flow in the direction of the unclean part of said filter . characterized in that there is no flow of air through the particulate filter in the first stage, and the air pressure in the filter is increased to pressure of about and between 4,5 bar to 6,0 bar.
Delivery device for delivering a game object, comprising: a drive having a drive body for driving the game object according to a controllable drive characteristic; and a control device for controlling the controllable drive characteristic as a function of at least one performance-physiological parameter, wherein the performance physiological parameter is an actual parameter of a player, wherein the control device is configured to control the controllable drive characteristic of the drive as a function of the performance physiological actual parameter and a performance-physiological target parameter, wherein the control of the drive characteristic of the drive body is only performed when the target-to-actual value difference reaches or exceeds a predetermined or adjustable threshold value. a drive having a drive body for driving the game object according to a controllable drive characteristic; and a control device for controlling the controllable drive characteristic as a function of at least one performance-physiological parameter, wherein the performance physiological parameter is an actual parameter of a player, wherein the control device is configured to control the controllable drive characteristic of the drive as a function of the performance physiological actual parameter and a performance-physiological target parameter, wherein the control of the drive characteristic of the drive body is only performed when the target-to-actual value difference reaches or exceeds a predetermined or adjustable threshold value.
Use of fibrosis inhibitor for the normalization of culture of corneal endothelial cells, wherein said fibrosis inhibitor comprises a p38 MAP kinase inhibiting agent.
A method comprising: heating, using a heat source , a reactor vessel including a substrate in a radially central core region of the reactor vessel , wherein the substrate comprises a porous preform; introducing, using at least one reactor inlet in an outer wall of the reactor vessel , a precursor gas to the reactor vessel , wherein the at least one reactor inlet is configured to produce swirling flow of the precursor gas around the radially central core region of the reactor vessel , and wherein a material deposits on the substrate from the precursor gas; and removing, using at least one reactor outlet , an exhaust gas from the reactor vessel ; characterised in that the method comprises the further step of: creating a gradient across the porous preform by maintaining at least one of: a dynamic pressure of the reactor vessel greater than a pressure in the porous preform; or an average temperature of the precursor gas less than an average temperature of the porous preform. heating, using a heat source , a reactor vessel including a substrate in a radially central core region of the reactor vessel , wherein the substrate comprises a porous preform; introducing, using at least one reactor inlet in an outer wall of the reactor vessel , a precursor gas to the reactor vessel , wherein the at least one reactor inlet is configured to produce swirling flow of the precursor gas around the radially central core region of the reactor vessel , and wherein a material deposits on the substrate from the precursor gas; and removing, using at least one reactor outlet , an exhaust gas from the reactor vessel ; a dynamic pressure of the reactor vessel greater than a pressure in the porous preform; or an average temperature of the precursor gas less than an average temperature of the porous preform.
Stylus for entering data on to an entry pad, said stylus comprising a body comprising a housing , said stylus comprising: - a reference element comprising two distinct portions: - a first portion seated within said housing ; - a second portion comprising a tip , the end of which is at least hemispherical; - a non-flexible, non-conductive damper , forming a cladding around at least one part of said reference element , comprising an external wall, called an external wall of said damper , said damper comprises a cylindrical sleeve comprising a first hemispherical end , the internal diameter of the cylindrical sleeve being substantially equal to the diameter of the at least hemispherical end of the reference element , the stylus further comprising a space left vacant between said first hemispherical end and the at least hemispherical end of the reference element , said space being filled with an electrically charged deformable material said damper further comprising a second end comprising a retaining ring for retaining said damper in said housing , said damper is mobile in translation according to the pressure exerted on the stylus. - a reference element comprising two distinct portions: - a first portion seated within said housing ; - a second portion comprising a tip , the end of which is at least hemispherical; - a non-flexible, non-conductive damper , forming a cladding around at least one part of said reference element , comprising an external wall, called an external wall of said damper , said damper comprises a cylindrical sleeve comprising a first hemispherical end , the internal diameter of the cylindrical sleeve being substantially equal to the diameter of the at least hemispherical end of the reference element , the stylus further comprising a space left vacant between said first hemispherical end and the at least hemispherical end of the reference element , said space being filled with an electrically charged deformable material said damper further comprising a second end comprising a retaining ring for retaining said damper in said housing , said damper is mobile in translation according to the pressure exerted on the stylus.
Fuel injection system with a fuel distributor which has a distributor tube , and with at least one holder which serves for fastening the fuel distributor to a mounted structure with at least one elastically deformable damping element , wherein a first half shell and a second half shell are provided, wherein, for fastening the tubular component to the mounted structure , the first half shell and the second half shell can be joined to each other in such a manner that the first half shell and the second half shell surround the tubular component and hold the tubular component by means of the elastic damping elements , characterized in that a plurality of elastically deformable damping elements are injection-moulded onto the holding region of the first half shell , and/or in that a plurality of elastically deformable damping elements are placed into the holding region of the first half shell , and in that a plurality of elastically deformable damping elements are injection-moulded onto the holding region of the second half shell , and/or in that a plurality of elastically deformable damping elements are placed into the holding region of the second half shell , wherein the elastically deformable damping elements which are injection-moulded onto the holding region of the first half shell or are placed into the holding region of the first half shell are configured in a strip-shaped or lip-shaped manner, and wherein the elastically deformable damping elements which are injection-moulded onto the holding region of the second half shell or are placed into the holding region of the second half shell are configured in a strip-shaped or lip-shaped manner, wherein the damping elements are each of partially annular configuration and, in the mounted state, in each case complement one another to form a ring which surrounds an outer side of the distributor tube .
An ultrasound imaging system (10;800) comprising: an ultrasound probe configured to receive ultrasound echoes from a subject to image a volume of the subject; a scan converter configured to generate a three dimensional data set from the ultrasound echoes; a volume renderer configured to calculate surface shading information of a surface of the 3D data set based, at least in part, on a location of a simulated light source (405;405a-e;705;915a-c;1015;1115) relative to the 3D data set and render a two dimensional projection image of the 3D data set , the 2D projection image including the shading information; and a user interface (24;805) comprising: a display (38;810;905;1005) configured to display the 2D projection image; and an input device comprising a user input element configured to receive user input to position the simulated light source (405;405a-e;705;915a-c;1015;1115) at a location within the 3D data set , wherein the simulated light source (405;405a-e;705;915a-c;1015;1115) comprises a plurality of simulated light sources including a first light source at a shallow depth near the image plane and a second light source at a deeper depth within the 3D data set relative to the first light source. an ultrasound probe configured to receive ultrasound echoes from a subject to image a volume of the subject; a scan converter configured to generate a three dimensional data set from the ultrasound echoes; a volume renderer configured to calculate surface shading information of a surface of the 3D data set based, at least in part, on a location of a simulated light source (405;405a-e;705;915a-c;1015;1115) relative to the 3D data set and render a two dimensional projection image of the 3D data set , the 2D projection image including the shading information; and a user interface (24;805) comprising: a display (38;810;905;1005) configured to display the 2D projection image; and an input device comprising a user input element configured to receive user input to position the simulated light source (405;405a-e;705;915a-c;1015;1115) at a location within the 3D data set , wherein the simulated light source (405;405a-e;705;915a-c;1015;1115) comprises a plurality of simulated light sources including a first light source at a shallow depth near the image plane and a second light source at a deeper depth within the 3D data set relative to the first light source. a display (38;810;905;1005) configured to display the 2D projection image; and an input device comprising a user input element configured to receive user input to position the simulated light source (405;405a-e;705;915a-c;1015;1115) at a location within the 3D data set , wherein the simulated light source (405;405a-e;705;915a-c;1015;1115) comprises a plurality of simulated light sources including a first light source at a shallow depth near the image plane and a second light source at a deeper depth within the 3D data set relative to the first light source.
A propulsion unit (112; 300), comprising: a motor rotor configured to spin about a central rotational axis ; propeller blades, including first and second propeller blades , each having a proximal base mounted to the motor rotor such that the propeller blades are rotatable about the central rotational axis, wherein the second propeller blade is pivotally attached to the motor rotor to pivot about the central rotational axis independent of the motor rotor by a limited angle; a pivot stop configured to mechanically limit an amount of pivoting of the second propeller blade relative to the first propeller blade; characterised in that the propulsion unit further comprises a washer flange disposed between the proximal bases of the first and second propeller blades and configured to offset the second propeller blade relative to the first propeller blade along the center rotational axis. a motor rotor configured to spin about a central rotational axis ; propeller blades, including first and second propeller blades , each having a proximal base mounted to the motor rotor such that the propeller blades are rotatable about the central rotational axis, wherein the second propeller blade is pivotally attached to the motor rotor to pivot about the central rotational axis independent of the motor rotor by a limited angle; a pivot stop configured to mechanically limit an amount of pivoting of the second propeller blade relative to the first propeller blade; characterised in that the propulsion unit further comprises a washer flange disposed between the proximal bases of the first and second propeller blades and configured to offset the second propeller blade relative to the first propeller blade along the center rotational axis.
A gas delivery apparatus for delivering a calibrant gas to an ionization chamber of a mass spectrometer , comprising: (a) a calibration receptacle containing the calibrant gas; (b) a vacuum pump operably connected with the mass spectrometer ; (c) a multiport valve for diverting the calibrant gas in the to the ionization chamber or to the vacuum pump ; and, (d) a first flow restrictor for metering the calibrant gas to the ionization chamber ; characterized in that the calibration receptacle contains a plurality of separated liquid calibrants, and wherein the calibration receptacle has a common headspace , wherein the calibrant gas mixture forms. (a) a calibration receptacle containing the calibrant gas; (b) a vacuum pump operably connected with the mass spectrometer ; (c) a multiport valve for diverting the calibrant gas in the to the ionization chamber or to the vacuum pump ; and, (d) a first flow restrictor for metering the calibrant gas to the ionization chamber ;