A system for monitoring health of a living subject , the system comprising: a hardware unit including a hardware processor , an analog-to-digital converter (ADC, 122, 222), and a system memory ; a hypotension prediction software code including a predictive weighting module stored in the system memory ; a hemodynamic sensor coupled to the hardware unit ; and a sensory alarm ; wherein the hardware processor is configured to execute the hypotension prediction software code to: obtain digital hemodynamic data converted, by the ADC (122 222), from a signal received from the hemodynamic sensor ; obtain one or more vital sign parameters characterizing vital sign data from the digital hemodynamic data , wherein one or more of said vital sign parameters includes a mean arterial pressure (MAP) of the living subject; derive differential parameters based on the one or more vital sign parameters characterizing the vital sign data; generate combinatorial parameters using the one or more vital sign parameters characterizing the vital sign data and the differential parameters; determine, using the predictive weighting module , a risk score corresponding to a probability of a future hypotension event for the living subject based on a weighted combination of a plurality of hypotension profiling parameters including the one or more vital sign parameters characterizing vital sign data, the differential parameters and the combinatorial parameters; and invoke the sensory alarm if the risk score satisfies a predetermined risk criterion, wherein the weighted combination of the plurality of hypotension profiling parameters results in the mean arterial pressure (MAP) of the living subject being substantially disregarded in determination of the risk score, or wherein the weighted combination of the plurality of hypotension profiling parameters results in the mean arterial pressure (MAP) of the living subject dominating determination of the risk score. a hardware unit including a hardware processor , an analog-to-digital converter (ADC, 122, 222), and a system memory ; a hypotension prediction software code including a predictive weighting module stored in the system memory ; a hemodynamic sensor coupled to the hardware unit ; and a sensory alarm ; obtain digital hemodynamic data converted, by the ADC (122 222), from a signal received from the hemodynamic sensor ; obtain one or more vital sign parameters characterizing vital sign data from the digital hemodynamic data , wherein one or more of said vital sign parameters includes a mean arterial pressure (MAP) of the living subject; derive differential parameters based on the one or more vital sign parameters characterizing the vital sign data; generate combinatorial parameters using the one or more vital sign parameters characterizing the vital sign data and the differential parameters; determine, using the predictive weighting module , a risk score corresponding to a probability of a future hypotension event for the living subject based on a weighted combination of a plurality of hypotension profiling parameters including the one or more vital sign parameters characterizing vital sign data, the differential parameters and the combinatorial parameters; and invoke the sensory alarm if the risk score satisfies a predetermined risk criterion, wherein the weighted combination of the plurality of hypotension profiling parameters results in the mean arterial pressure (MAP) of the living subject being substantially disregarded in determination of the risk score, or wherein the weighted combination of the plurality of hypotension profiling parameters results in the mean arterial pressure (MAP) of the living subject dominating determination of the risk score. <EOS>