A digital microscope system , comprising: a plurality of camera systems for imaging a target region of an object , each camera system comprising a digital camera and an optical imaging system being aligned along an optical axis (O1, 02, 03) of said camera system , wherein the optical axes (O1, O2, O3) of the camera systems are parallel to each other; a microscope stage , on which the object is to be arranged; a positioning device ; and a controller configured to control the positioning device to move the plurality of camera systems and the microscope stage relative to each other orthogonally to the optical axes (O1, O2, O3) of the camera systems for selectively aligning any one of the camera systems with the target region of the object , characterized in that the camera systems are configured to generate digital image data representing the target region in accordance with a setting, said setting determining which one of the plurality of camera systems is to be aligned with the object ; the controller is configured to generate monitor image data corresponding to the digital image data generated in accordance with the setting, the monitor image data being configured to be displayed as a monitor image; the controller is configured to change the setting in response to a user input; and the controller is configured to compensate for a delay in updating the monitor image data in accordance with the changed setting by: storing the digital image data generated in accordance with the unchanged setting in response to the user input and generating simulation monitor image data by performing digital image processing on the stored digital image data taking into account the changed setting, the simulation monitor image data being configured to be displayed as a simulation monitor image during the delay. a plurality of camera systems for imaging a target region of an object , each camera system comprising a digital camera and an optical imaging system being aligned along an optical axis (O1, 02, 03) of said camera system , wherein the optical axes (O1, O2, O3) of the camera systems are parallel to each other; a microscope stage , on which the object is to be arranged; a positioning device ; and a controller configured to control the positioning device to move the plurality of camera systems and the microscope stage relative to each other orthogonally to the optical axes (O1, O2, O3) of the camera systems for selectively aligning any one of the camera systems with the target region of the object , characterized in that the camera systems are configured to generate digital image data representing the target region in accordance with a setting, said setting determining which one of the plurality of camera systems is to be aligned with the object ; the controller is configured to generate monitor image data corresponding to the digital image data generated in accordance with the setting, the monitor image data being configured to be displayed as a monitor image; the controller is configured to change the setting in response to a user input; and the controller is configured to compensate for a delay in updating the monitor image data in accordance with the changed setting by: storing the digital image data generated in accordance with the unchanged setting in response to the user input and generating simulation monitor image data by performing digital image processing on the stored digital image data taking into account the changed setting, the simulation monitor image data being configured to be displayed as a simulation monitor image during the delay. <EOS>