mhurhangee/patent-ind-claim-en huggingface dataset:
A composition comprising an anti-tumor necrosis factor (TNF)-alpha polypeptide, wherein the anti-TNF-alpha polypeptide is etanercept, wherein the composition is prepared by a process comprising: (a) providing a mixture comprising etanercept and impurities comprising aggregates of etanercept and misfolded forms of etanercept, (b) contacting the mixture with a hydrophobic interaction chromatography (HIC) resin, such that etanercept binds to the HIC resin, and (c) eluting etanercept from the HIC resin with an elution buffer, thereby obtaining the composition comprising etanercept wherein said composition produces a reduced level of immunogenicity in the subject as compared to an ENBREL TM etanercept composition with an equivalent concentration of the etanercept, and wherein, when hydrophobic interaction high performance liquid chromatography (HI-HPLC) is performed on the composition, the composition contains a Peak 3 amount of about 12 wt.% or less. wherein the anti-TNF-alpha polypeptide is etanercept, wherein the composition is prepared by a process comprising: (a) providing a mixture comprising etanercept and impurities comprising aggregates of etanercept and misfolded forms of etanercept, (b) contacting the mixture with a hydrophobic interaction chromatography (HIC) resin, such that etanercept binds to the HIC resin, and (c) eluting etanercept from the HIC resin with an elution buffer, thereby obtaining the composition comprising etanercept (a) providing a mixture comprising etanercept and impurities comprising aggregates of etanercept and misfolded forms of etanercept, (b) contacting the mixture with a hydrophobic interaction chromatography (HIC) resin, such that etanercept binds to the HIC resin, and (c) eluting etanercept from the HIC resin with an elution buffer, thereby obtaining the composition comprising etanercept wherein said composition produces a reduced level of immunogenicity in the subject as compared to an ENBREL TM etanercept composition with an equivalent concentration of the etanercept, and wherein, when hydrophobic interaction high performance liquid chromatography (HI-HPLC) is performed on the composition, the composition contains a Peak 3 amount of about 12 wt.% or less.
An image engraving apparatus , comprising: a floating base elastically supported; a vibration actuator (PAZ, PAY) fixed to the floating base and including an output portion and stacked piezoelectric elements , the output portion configured to output vibration generated by deformation of the piezoelectric elements ; a stylus holder connected to the output portion to receive the vibration; a stylus supported with the stylus holder to be vibrated according to the vibration received by the stylus holder and to engrave an image on a medium (C) to be engraved; a supporting spring supporting the stylus holder to the floating base to allow the stylus holder to be vibrated when the stylus holder receives the vibration; a retainer positionally adjustably supported to the floating base to come into contact with the medium (C) to be engraved and position the stylus relatively to the medium (C) to be engraved; and a drive circuit including at least one image signal processor electrically connected to the vibration actuator (PAZ, PAY) so that a relative movement between the stylus vibrated and the medium (C) to be engraved is caused based on an image signal to engrave an image on the medium (C) to be engraved. a floating base elastically supported; a vibration actuator (PAZ, PAY) fixed to the floating base and including an output portion and stacked piezoelectric elements , the output portion configured to output vibration generated by deformation of the piezoelectric elements ; a stylus holder connected to the output portion to receive the vibration; a stylus supported with the stylus holder to be vibrated according to the vibration received by the stylus holder and to engrave an image on a medium (C) to be engraved; a supporting spring supporting the stylus holder to the floating base to allow the stylus holder to be vibrated when the stylus holder receives the vibration; a retainer positionally adjustably supported to the floating base to come into contact with the medium (C) to be engraved and position the stylus relatively to the medium (C) to be engraved; and a drive circuit including at least one image signal processor electrically connected to the vibration actuator (PAZ, PAY) so that a relative movement between the stylus vibrated and the medium (C) to be engraved is caused based on an image signal to engrave an image on the medium (C) to be engraved.
Single-piece optical vehicle part (100; 200) comprising: - a plurality of entrance dioptric interfaces (111, 121, 131; 80, 81, 82, 84) and/or a plurality of exit dioptric interfaces ; - at least one junction between two adjacent entrance dioptric interfaces and/or at least one junction between two adjacent exit dioptric interfaces ; the single-piece optical part (100; 200) being characterized in that the junction between two adjacent entrance dioptric interfaces and/or the junction between two adjacent exit dioptric interfaces has a structural modification (7, 73; 70, 71, 72) allowing light to be absorbed and/or scattered, and in that the structural modification (7, 73; 70, 71, 72) is produced by laser. - a plurality of entrance dioptric interfaces (111, 121, 131; 80, 81, 82, 84) and/or a plurality of exit dioptric interfaces ; - at least one junction between two adjacent entrance dioptric interfaces and/or at least one junction between two adjacent exit dioptric interfaces ;
A method performed by a terminal in a wireless communication system, comprising: receiving, from a base station, a radio resource control, RRC, reconfiguration message; identifying whether the RRC reconfiguration message includes a packet data convergence protocol, PDCP, re-establish indication associated with a data radio bearer, DRB, or not; performing PDCP re-establishment for the DRB, in case that the RRC reconfiguration message includes the PDCP re-establish indication; and not performing the PDCP re-establishment and performing, based on a retransmission indication, a retransmission of PDCP data Protocol Data Unit, PDU, for the DRB that have not been acknowledged, in case that the RRC reconfiguration message does not include the PDCP re-establish indication, wherein the DRB is an acknowledged mode, AM, DRB, wherein, in case that a security key refresh is required, the PDCP re-establish indication is included in the RRC reconfiguration message received from the base station, and, wherein, in case that the security key refresh is not needed, the PDCP re-establish indication is not included in the RRC reconfiguration message received from the base station. receiving, from a base station, a radio resource control, RRC, reconfiguration message; identifying whether the RRC reconfiguration message includes a packet data convergence protocol, PDCP, re-establish indication associated with a data radio bearer, DRB, or not; performing PDCP re-establishment for the DRB, in case that the RRC reconfiguration message includes the PDCP re-establish indication; and not performing the PDCP re-establishment and performing, based on a retransmission indication, a retransmission of PDCP data Protocol Data Unit, PDU, for the DRB that have not been acknowledged, in case that the RRC reconfiguration message does not include the PDCP re-establish indication, wherein the DRB is an acknowledged mode, AM, DRB, wherein, in case that a security key refresh is required, the PDCP re-establish indication is included in the RRC reconfiguration message received from the base station, and, wherein, in case that the security key refresh is not needed, the PDCP re-establish indication is not included in the RRC reconfiguration message received from the base station.
Kinetic electric energy storage, where a flywheel is implemented as an annulus and consists of an enclosure housing , which includes axially running cables , where the cables are routed within the enclosure housing , characterized in that a clamping device is attached, both at the beginning as well as at the end of the cables , so that by means of this clamping device the voltage of the cables can be modified continuously and the kinetic power storage is operated in vacuum and/or at reduced pressure and at a deep-freeze temperature of - 190°C, where the magnetic storage of the centrifugal masses is implemented here from the enclosure housing and the cables , with the use of high-temperature superconductors as well as permanent or electric magnets , and rotate the centrifugal masses along a circular orbit by means of a drive, where the drive consists of linear motors , which are arranged along the entire length of the circular orbit.
An agricultural vehicle having a cooling system comprising a fan and a radiator mounted on a mounting plate , said fan provided with an upper shroud part which extends rearwards from the upper half of the fan towards the radiator over the plate ,said cooling system housed in a bonnet of the vehicle , characterised in that the fan includes a fan ring , and the cooling system has a complete fan shroud formed by the fan ring , the upper shroud part , two removable side panels and the mounting plate wherein the complete fan shroud extends from the fan to the radiator to direct air between the fan and the radiator in a direction parallel or substantially parallel to the longitudinal axis of the vehicle.
Connecting device for anchoring seat modules, wherein said connecting device comprises: an arm configured to be connected at a first end, by means of an articulated joint with respect to an axis, to a first module, wherein said arm comprises a serrated slot , open at a second end; and a pivot configured to be attached to a second module; the pivot comprises a cylindrical shape comprising a serrated side area, wherein the arm and the pivot are configured to be assembled by inserting the serrated side area of the pivot into the open serrated slot of the arm by moving them towards each other in a direction of approach in a transverse plane, wherein the teeth of the slot and the pivot are configured to block the extraction of the pivot with respect to the slot of the arm when being moved in a direction of separation in the transverse plane; and wherein the pivot is configured to be extracted from the slot of the arm , by moving said pivot with respect to the arm in a longitudinal direction, perpendicular to the transverse plane; wherein the connecting device comprises a support piece configured to be positioned between the arm and the first module when connecting said arm to said first module, said support piece being connected in an articulated manner with respect to the arm and is configured to be connected in a rigid manner with respect to the first module; characterized in that the support piece comprises a first and second stop configured to limit the rotation of the arm with respect to said support piece between 45o and 90o in the transverse plane. an arm configured to be connected at a first end, by means of an articulated joint with respect to an axis, to a first module, wherein said arm comprises a serrated slot , open at a second end; and a pivot configured to be attached to a second module; the pivot comprises a cylindrical shape comprising a serrated side area, wherein the arm and the pivot are configured to be assembled by inserting the serrated side area of the pivot into the open serrated slot of the arm by moving them towards each other in a direction of approach in a transverse plane, wherein the teeth of the slot and the pivot are configured to block the extraction of the pivot with respect to the slot of the arm when being moved in a direction of separation in the transverse plane; and wherein the pivot is configured to be extracted from the slot of the arm , by moving said pivot with respect to the arm in a longitudinal direction, perpendicular to the transverse plane; wherein the connecting device comprises a support piece configured to be positioned between the arm and the first module when connecting said arm to said first module, said support piece being connected in an articulated manner with respect to the arm and is configured to be connected in a rigid manner with respect to the first module; characterized in that the support piece comprises a first and second stop configured to limit the rotation of the arm with respect to said support piece between 45o and 90o in the transverse plane.
A method of manufacturing a diester-based compound, which is performed using a continuous process comprising a reaction part in which a total of n reaction units spanning from a first reaction unit to an n th reaction unit are connected in series, wherein each of the reaction units comprises a reactor and a layer separator, and the method comprises: supplying a feed stream comprising a dicarboxylic acid and an alcohol into the first reactor, esterifying the feed stream to prepare a reaction product, and supplying a lower discharge stream comprising the reaction product into the reactors of the rear reaction units (S10); supplying an upper discharge stream of the first reactor into a first layer separator, and refluxing a lower discharge stream comprising an alcohol from the first layer separator into the first reactor (S20); and supplying an upper discharge stream of at least one reactor of second to and n th reactors into each of the layer separators, splitting a portion of the lower discharge stream comprising the alcohol from each of the layer separators, and refluxing only a portion of the split stream into each of the reactors (Step S30). wherein each of the reaction units comprises a reactor and a layer separator, and the method comprises: supplying a feed stream comprising a dicarboxylic acid and an alcohol into the first reactor, esterifying the feed stream to prepare a reaction product, and supplying a lower discharge stream comprising the reaction product into the reactors of the rear reaction units (S10); supplying an upper discharge stream of the first reactor into a first layer separator, and refluxing a lower discharge stream comprising an alcohol from the first layer separator into the first reactor (S20); and supplying an upper discharge stream of at least one reactor of second to and n th reactors into each of the layer separators, splitting a portion of the lower discharge stream comprising the alcohol from each of the layer separators, and refluxing only a portion of the split stream into each of the reactors (Step S30). supplying a feed stream comprising a dicarboxylic acid and an alcohol into the first reactor, esterifying the feed stream to prepare a reaction product, and supplying a lower discharge stream comprising the reaction product into the reactors of the rear reaction units (S10); supplying an upper discharge stream of the first reactor into a first layer separator, and refluxing a lower discharge stream comprising an alcohol from the first layer separator into the first reactor (S20); and supplying an upper discharge stream of at least one reactor of second to and n th reactors into each of the layer separators, splitting a portion of the lower discharge stream comprising the alcohol from each of the layer separators, and refluxing only a portion of the split stream into each of the reactors (Step S30).
A fiber wound body (11; 51) comprising: reinforced fiber yarns (12, 13, 14; 52, 53) wound about a winding axis (L), wherein the fiber wound body (11; 51) is characterized in that : each of the reinforced fiber yarns (12, 13, 14; 52, 53) is formed by spinning non-continuous fibers and includes a gradual cross-section change portion (20; 56), and the gradual cross-section change portion (20; 56) has a fiber content rate that is constant in a longitudinal direction of the yarn and has a cross section that gradually changes, wherein the fiber content rate of each of the reinforced fiber yarns refers to the proportion of fibers of the reinforced fiber yarn occupied in the total cross-sectional area of the reinforced fiber yarns. reinforced fiber yarns (12, 13, 14; 52, 53) wound about a winding axis (L), wherein the fiber wound body (11; 51) is characterized in that : each of the reinforced fiber yarns (12, 13, 14; 52, 53) is formed by spinning non-continuous fibers and includes a gradual cross-section change portion (20; 56), and the gradual cross-section change portion (20; 56) has a fiber content rate that is constant in a longitudinal direction of the yarn and has a cross section that gradually changes, wherein the fiber content rate of each of the reinforced fiber yarns refers to the proportion of fibers of the reinforced fiber yarn occupied in the total cross-sectional area of the reinforced fiber yarns. each of the reinforced fiber yarns (12, 13, 14; 52, 53) is formed by spinning non-continuous fibers and includes a gradual cross-section change portion (20; 56), and the gradual cross-section change portion (20; 56) has a fiber content rate that is constant in a longitudinal direction of the yarn and has a cross section that gradually changes, wherein the fiber content rate of each of the reinforced fiber yarns refers to the proportion of fibers of the reinforced fiber yarn occupied in the total cross-sectional area of the reinforced fiber yarns.
A connector having a connector housing , comprising: a metal securing sleeve , having a plurality of clamping fingers , the securing sleeve being designed to slide onto a cable , and a metal housing nut , the housing nut being designed to slide over the securing sleeve and comprising a displacement element arranged radially on the inside, and the plurality of clamping fingers being displaced radially inwards in an operating state of the housing nut and of the displacement element such that the plurality of clamping fingers are pressed against the associated cable , characterized in that the displacement element is made of an electrically non-conductive material. a metal securing sleeve , having a plurality of clamping fingers , the securing sleeve being designed to slide onto a cable , and a metal housing nut , the housing nut being designed to slide over the securing sleeve and comprising a displacement element arranged radially on the inside, and the plurality of clamping fingers being displaced radially inwards in an operating state of the housing nut and of the displacement element such that the plurality of clamping fingers are pressed against the associated cable , characterized in that the displacement element is made of an electrically non-conductive material.
Moving walkway comprising: at least one endless belt moving in a conveyance direction along a closed loop, the closed loop comprising a conveyance portion and a return portion extending between two turnaround portions , respectively; a plurality of pallets ; and a plurality of linkages rotatably connecting adjacent pallets with each other; wherein at least one mounting portion of each pallet is rotatably connected to the at least one belt ; and wherein each of the linkages comprises a first linkage element and a second linkage element , wherein the first linkage elements are spaced apart from the second linkage elements in the lateral direction, wherein the first and second linkage elements in particular are located on opposite lateral sides of the belt ; and wherein the moving walkway comprises first linkage axles extending between the first sides of the first and second linkage elements ; and characterized in that the first linkage axles are fixed to the at least one belt at a position corresponding to the neutral phase of the at least one belt which is neither compressed nor stretched when the belt is bent; and/or wherein the moving walkway further comprises second linkage axles extending between the second sides of the first and second linkage elements . at least one endless belt moving in a conveyance direction along a closed loop, the closed loop comprising a conveyance portion and a return portion extending between two turnaround portions , respectively; a plurality of pallets ; and a plurality of linkages rotatably connecting adjacent pallets with each other; wherein at least one mounting portion of each pallet is rotatably connected to the at least one belt ; and wherein each of the linkages comprises a first linkage element and a second linkage element , wherein the first linkage elements are spaced apart from the second linkage elements in the lateral direction, wherein the first and second linkage elements in particular are located on opposite lateral sides of the belt ; and wherein the moving walkway comprises first linkage axles extending between the first sides of the first and second linkage elements ; and characterized in that the first linkage axles are fixed to the at least one belt at a position corresponding to the neutral phase of the at least one belt which is neither compressed nor stretched when the belt is bent; and/or wherein the moving walkway further comprises second linkage axles extending between the second sides of the first and second linkage elements .
A method for self-tuning a computing system, comprising: mapping a current first workload of the computing system to at least one bucket of related workloads, wherein at least one of the at least one bucket has a plurality of second workloads mapped thereto, wherein the related workloads of one of the at least one bucket behave similarly with respect to a target metric, wherein each target metric defines at least one optimization attribute, wherein the mapping is performed using a locality based hashing function applied on a plurality of workload-related values and a history of the workload-related values; measuring a current operation metric representing a current operation of the computing system; determining, based on the current operation metric, at least one optimization scheme for each of the at least one bucket, wherein the at least one optimization scheme includes at least a list of system knobs having optimal values configured to adjust the operation of the computing system to meet at least one predefined target metric, wherein each system knob is a configuration parameter for the computing system; and setting each of the system knobs listed in the at least one determined optimization scheme to its respective value. mapping a current first workload of the computing system to at least one bucket of related workloads, wherein at least one of the at least one bucket has a plurality of second workloads mapped thereto, wherein the related workloads of one of the at least one bucket behave similarly with respect to a target metric, wherein each target metric defines at least one optimization attribute, wherein the mapping is performed using a locality based hashing function applied on a plurality of workload-related values and a history of the workload-related values; measuring a current operation metric representing a current operation of the computing system; determining, based on the current operation metric, at least one optimization scheme for each of the at least one bucket, wherein the at least one optimization scheme includes at least a list of system knobs having optimal values configured to adjust the operation of the computing system to meet at least one predefined target metric, wherein each system knob is a configuration parameter for the computing system; and setting each of the system knobs listed in the at least one determined optimization scheme to its respective value.