mhurhangee/patent-ind-claim-en huggingface dataset:
A system for delivering therapy to terminate a tachycardia event in a heart of a patient, comprising: a pacing device configured to be implanted in the patient's body and comprising a processor ; a plurality of electrodes coupled to the processor and sized for implantation within the patient's body; wherein the processor is configured to: sense cardiac signals from the heart and detect a tachycardia event in response to the sensed cardiac signals; deliver one or more pacing pulses to the heart, via one or more pacing electrodes, the pacing pulses having one or more pacing cycle lengths; monitor cardiac signals during the delivery of the one or more pacing pulses to identify tachycardia termination/block within the reentrant circuit; and adjust the delivery of the one or more pacing pulses in response to the monitored cardiac signals, wherein the tachycardia termination/block within the reentrant circuit is identified by the processor by monitoring cardiac signals using one or more sensing electrodes other than the one or more pacing electrodes. a pacing device configured to be implanted in the patient's body and comprising a processor ; a plurality of electrodes coupled to the processor and sized for implantation within the patient's body; wherein the processor is configured to: sense cardiac signals from the heart and detect a tachycardia event in response to the sensed cardiac signals; deliver one or more pacing pulses to the heart, via one or more pacing electrodes, the pacing pulses having one or more pacing cycle lengths; monitor cardiac signals during the delivery of the one or more pacing pulses to identify tachycardia termination/block within the reentrant circuit; and adjust the delivery of the one or more pacing pulses in response to the monitored cardiac signals, wherein the tachycardia termination/block within the reentrant circuit is identified by the processor by monitoring cardiac signals using one or more sensing electrodes other than the one or more pacing electrodes. sense cardiac signals from the heart and detect a tachycardia event in response to the sensed cardiac signals; deliver one or more pacing pulses to the heart, via one or more pacing electrodes, the pacing pulses having one or more pacing cycle lengths; monitor cardiac signals during the delivery of the one or more pacing pulses to identify tachycardia termination/block within the reentrant circuit; and adjust the delivery of the one or more pacing pulses in response to the monitored cardiac signals, wherein the tachycardia termination/block within the reentrant circuit is identified by the processor by monitoring cardiac signals using one or more sensing electrodes other than the one or more pacing electrodes.
A method of detecting a PRKACB gene fusion in a biological sample, wherein the PRKACB gene fusion is a CEP170:PRKACB or RBM17:PRKACB fusion, said method comprising: a) contacting a biological sample from a mammal with a reagent that is an oligonucleotide that hybridizes to a fusion junction of the PRKACB gene fusion of SEQ ID NO: 1 or 3; and b) detecting binding between the PRKACB gene fusion and the reagent. a) contacting a biological sample from a mammal with a reagent that is an oligonucleotide that hybridizes to a fusion junction of the PRKACB gene fusion of SEQ ID NO: 1 or 3; and b) detecting binding between the PRKACB gene fusion and the reagent.
A method of operating a node in a communication network, the method comprising: receiving a request from a first radio access node in the communication network for information on a second radio access node in the communication network, the information relating to whether a first base key that was used to determine a first encryption key for encrypting communications between a communication device and the first radio access node can be used for determining a second encryption key for encrypting communications between the communication device and the second radio access node; determining whether the first base key can be used by a second radio access node, wherein the step of determining comprises determining that the first base key can be used by the second radio access node if the first radio access node and the second radio access node are part of the same security zone, wherein the first radio access node and the second radio access node are part of the same security zone if the first radio access node and the second radio access node are: (a) running as separate virtual machines on the same hardware; (b) two containers within the same virtual machine; (c) implemented on boards in the same physical rack; (d) determined by a security policy as belonging to the same security zone; or (e) physically located in the same site; and sending information on the second radio access node to the first radio access node, the information indicating whether the first base key can be used by the second radio access node. receiving a request from a first radio access node in the communication network for information on a second radio access node in the communication network, the information relating to whether a first base key that was used to determine a first encryption key for encrypting communications between a communication device and the first radio access node can be used for determining a second encryption key for encrypting communications between the communication device and the second radio access node; determining whether the first base key can be used by a second radio access node, wherein the step of determining comprises determining that the first base key can be used by the second radio access node if the first radio access node and the second radio access node are part of the same security zone, wherein the first radio access node and the second radio access node are part of the same security zone if the first radio access node and the second radio access node are: (a) running as separate virtual machines on the same hardware; (b) two containers within the same virtual machine; (c) implemented on boards in the same physical rack; (d) determined by a security policy as belonging to the same security zone; or (e) physically located in the same site; and sending information on the second radio access node to the first radio access node, the information indicating whether the first base key can be used by the second radio access node.
A tube pump , comprising: a flexible tube for conveying a fluid; a holder part holding the tube so that the tube is at least partially bent; a driving part ; and at least one pressing part , rotationally driven around a first central axis (A1) by the driving part , and pressing the tube along the bent portion of the tube held by the holder part while rotating around the first central axis (A1), thereby conveying the fluid in the tube , wherein the holder part has a first wall surface facing the pressing part ; the tube pump being characterized in that the pressing part has, on a surface thereof facing the tube , an inclined plane inclined from the side of the tube toward the side of the pressing part in a radially outward direction with reference to the first central axis (A1) so as to be away from the first wall surface , and the inclined plane presses the tube toward the first wall surface . a flexible tube for conveying a fluid; a holder part holding the tube so that the tube is at least partially bent; a driving part ; and at least one pressing part , rotationally driven around a first central axis (A1) by the driving part , and pressing the tube along the bent portion of the tube held by the holder part while rotating around the first central axis (A1), thereby conveying the fluid in the tube , wherein the holder part has a first wall surface facing the pressing part ; the tube pump being characterized in that the pressing part has, on a surface thereof facing the tube , an inclined plane inclined from the side of the tube toward the side of the pressing part in a radially outward direction with reference to the first central axis (A1) so as to be away from the first wall surface , and the inclined plane presses the tube toward the first wall surface .
An accelerator for use in a mass spectrometer , the accelerator comprising: a three ring stack of conductive plates with a gap separating any pair of said plates; a first resistor voltage divider electrically coupled to said plates; a single compensation capacitor coupled to said plates and configured to allow generating at each plate, in response to application of an RF voltage pulse across the stack, said RF voltage pulse having an amplitude that varies substantially linearly from a first plate in said stack to a last plate in said stack; wherein the single compensation capacitor is configured to correct capacitive effects that cause non-linear voltage division and a non-homogeneous electric field in said stack; wherein the three ring stack comprises a first ring electrically coupled to a source configured to provide said RF pulse, a second ring connected to ground, and an intermediate ring connected to both the first ring and second ring by resistors; and wherein the first ring is also connected to the intermediate ring by said single compensation capacitor. a three ring stack of conductive plates with a gap separating any pair of said plates; a first resistor voltage divider electrically coupled to said plates; a single compensation capacitor coupled to said plates and configured to allow generating at each plate, in response to application of an RF voltage pulse across the stack, said RF voltage pulse having an amplitude that varies substantially linearly from a first plate in said stack to a last plate in said stack; wherein the single compensation capacitor is configured to correct capacitive effects that cause non-linear voltage division and a non-homogeneous electric field in said stack; wherein the three ring stack comprises a first ring electrically coupled to a source configured to provide said RF pulse, a second ring connected to ground, and an intermediate ring connected to both the first ring and second ring by resistors; and wherein the first ring is also connected to the intermediate ring by said single compensation capacitor.
Melting plant comprising an electric furnace , provided with one or more electrodes and chemical substances introduction means , and a management apparatus comprising a decoupling unit disposed between an electricity grid and said electric furnace , wherein said management apparatus comprises a control unit that has: - a calculation module programmed to implement an optimization function that automatically generates a current melting profile that minimizes a cost function of electrical and chemical energy, and - a management module configured to receive from said calculation module the data relating to said melting profile and to translate them into operating signals to be sent respectively to said decoupling unit and to said chemical substances introduction means , characterized in that said control unit that has a storage module which has a database in which a plurality of melting profiles are stored, wherein said calculation module is configured to perform a comparison between parameters relating to a determinate melting condition to be achieved in said electric furnace and corresponding operating parameters which have occurred in previous meltings, so as to select one or more base melting profiles from the database of said storage module . - a calculation module programmed to implement an optimization function that automatically generates a current melting profile that minimizes a cost function of electrical and chemical energy, and - a management module configured to receive from said calculation module the data relating to said melting profile and to translate them into operating signals to be sent respectively to said decoupling unit and to said chemical substances introduction means ,
A method of selecting a radiation therapy treatment plan for a patient , the treatment plan implemented through a radiation delivery system including a gantry configured to rotate around a couch , the couch movable in a linear direction relative to the gantry , the movement of the couch and the gantry creating a helical delivery path having a pitch, and a radiation module coupled to the gantry and configured to deliver a radiation beam , the beam having a beam weight corresponding to a radiation fluence, the method comprising: receiving, by a controller , an objective including at least one from a list including a desired dose, a desired dose distribution, and a dose constraint; optimizing, by the controller , the pitch based on the objective to obtain an optimized pitch; optimizing, by the controller , the beam weight based on the objective to obtain optimized beam weight; determining, by the controller , based on the optimized pitch and the optimized beam weight at least one from the following list including a treatment plan and a dose; and outputting, by the controller , the at least one of the treatment plan and the dose, wherein optimizing the pitch includes optimizing the pitch using a first geometry, and wherein optimizing the beam weight includes optimizing the beam weight using a second geometry different from the first geometry. receiving, by a controller , an objective including at least one from a list including a desired dose, a desired dose distribution, and a dose constraint; optimizing, by the controller , the pitch based on the objective to obtain an optimized pitch; optimizing, by the controller , the beam weight based on the objective to obtain optimized beam weight; determining, by the controller , based on the optimized pitch and the optimized beam weight at least one from the following list including a treatment plan and a dose; and outputting, by the controller , the at least one of the treatment plan and the dose, wherein optimizing the pitch includes optimizing the pitch using a first geometry, and wherein optimizing the beam weight includes optimizing the beam weight using a second geometry different from the first geometry.
A method of producing a V L antigen-binding protein that specifically binds a steroid comprising the steps of: (a) immunizing a genetically modified mouse with said steroid or said steroid linked to a carrier, wherein the genetically modified mouse comprises (i) unrearranged human immunoglobulin light chain variable (V L ) and light chain joining (J L ) gene segments operably linked to a mouse immunoglobulin heavy chain constant region nucleic acid sequence, and (ii) unrearranged human immunoglobulin light chain variable (V L ) and immunoglobulin light chain joining (J L ) gene segments operably linked to a mouse immunoglobulin light chain constant region nucleic acid sequence; and (b) isolating a V L antigen-binding protein, or cell expressing the V L antigen-binding protein, from the immunized mouse, wherein the V L antigen-binding protein comprises a first and a second immunoglobulin light chain variable domain, wherein the first immunoglobulin light chain variable domain is operably linked to an immunoglobulin heavy chain constant domain, wherein the second immunoglobulin light chain variable domain is operably linked to an immunoglobulin light chain constant domain, and wherein the first and the second immunoglobulin light chain variable domains have heterogeneous sequences and are associated to form a binding pocket of the V L antigen binding protein that specifically binds said steroid with a K D of 50 nM or less. (a) immunizing a genetically modified mouse with said steroid or said steroid linked to a carrier, wherein the genetically modified mouse comprises (i) unrearranged human immunoglobulin light chain variable (V L ) and light chain joining (J L ) gene segments operably linked to a mouse immunoglobulin heavy chain constant region nucleic acid sequence, and (ii) unrearranged human immunoglobulin light chain variable (V L ) and immunoglobulin light chain joining (J L ) gene segments operably linked to a mouse immunoglobulin light chain constant region nucleic acid sequence; and (i) unrearranged human immunoglobulin light chain variable (V L ) and light chain joining (J L ) gene segments operably linked to a mouse immunoglobulin heavy chain constant region nucleic acid sequence, and (ii) unrearranged human immunoglobulin light chain variable (V L ) and immunoglobulin light chain joining (J L ) gene segments operably linked to a mouse immunoglobulin light chain constant region nucleic acid sequence; and (b) isolating a V L antigen-binding protein, or cell expressing the V L antigen-binding protein, from the immunized mouse,
A geothermal plant for extracting energy from a geothermal reservoir located below the ocean bottom, the geothermal plant comprising: a floating platform ; a riser that extends from a well drilled into the geothermal reservoir , to the floating platform ; an electrical pump having a mechanical actuation part located in a bore of the riser , and an electronic part located outside the riser, wherein the electrical pump is configured to pump a geothermal liquid from the geothermal reservoir to the floating platform ; and a power plant located on the floating platform and configured to use a steam produced by the geothermal liquid to generate electrical power, wherein the electrical pump is placed at a depth of the riser where the geothermal liquid is in a single-phase. a floating platform ; a riser that extends from a well drilled into the geothermal reservoir , to the floating platform ; an electrical pump having a mechanical actuation part located in a bore of the riser , and an electronic part located outside the riser, wherein the electrical pump is configured to pump a geothermal liquid from the geothermal reservoir to the floating platform ; and a power plant located on the floating platform and configured to use a steam produced by the geothermal liquid to generate electrical power, wherein the electrical pump is placed at a depth of the riser where the geothermal liquid is in a single-phase.
A hole saw movable about a rotational axis in a cutting direction to cut into a workpiece , the hole saw comprising: a cylindrical body including a sidewall having a first end and a second end opposite the first end , the cylindrical body also including a gullet formed in the sidewall between a leading surface , a trailing surface , and a bottom surface of the sidewall , the trailing surface defining a curved portion having a first radius , the bottom surface having a second radius , the first radius being larger than the second radius ; and a cutting tooth coupled to the first end of the sidewall adjacent the gullet ; characterized in that a first portion of the trailing surface extending between the cutting tooth and the curved portion is a substantially linear surface. a cylindrical body including a sidewall having a first end and a second end opposite the first end , the cylindrical body also including a gullet formed in the sidewall between a leading surface , a trailing surface , and a bottom surface of the sidewall , the trailing surface defining a curved portion having a first radius , the bottom surface having a second radius , the first radius being larger than the second radius ; and a cutting tooth coupled to the first end of the sidewall adjacent the gullet ; characterized in that a first portion of the trailing surface extending between the cutting tooth and the curved portion is a substantially linear surface.
Turbine engine, comprising two structural annular casings which are interconnected by means for absorbing thrust forces from the engine, which comprise connecting rods , characterised in that these means for absorbing thrust further comprise at least one accessory gearbox which is fixed to a first of said casings and which is connected by said connecting rods to the other of said casings .
A method of controlling an interactive display , the method comprising: receiving position data representing a series of positions, over time, of an input object relative to the interactive display ; predicting a plurality of future positions of the input object based on the position data, wherein the predicted positions all relate to a future common point in time; evaluating a confidence measure for each of the plurality of predicted future positions to determine a respective value of the confidence measure for each of the future positions, representing a probability that the input object will move to the respective predicted future position; applying a validation process to the plurality of predicted future positions, wherein the validation process uses the respective value of the confidence measure for each of the predicted future positions to assess the predicted future positions against one or more validation criteria; if the predicted future positions do not meet the one or more validation criteria, predicting a second and smaller plurality of positions for a second future common point in time wherein the second future common point in time is sooner than the future common point in time for the plurality of predicted positions which did not meet the validation criteria; and updating the display based on the predicted future positions. receiving position data representing a series of positions, over time, of an input object relative to the interactive display ; predicting a plurality of future positions of the input object based on the position data, wherein the predicted positions all relate to a future common point in time; evaluating a confidence measure for each of the plurality of predicted future positions to determine a respective value of the confidence measure for each of the future positions, representing a probability that the input object will move to the respective predicted future position; applying a validation process to the plurality of predicted future positions, wherein the validation process uses the respective value of the confidence measure for each of the predicted future positions to assess the predicted future positions against one or more validation criteria; if the predicted future positions do not meet the one or more validation criteria, predicting a second and smaller plurality of positions for a second future common point in time wherein the second future common point in time is sooner than the future common point in time for the plurality of predicted positions which did not meet the validation criteria; and updating the display based on the predicted future positions.