mhurhangee/patent-ind-claim-en huggingface dataset:
A cutting insert for a tool for machining a workpiece, wherein the cutting insert comprises: - a clamping section which comprises at least one coolant channel which is configured as a through-hole; - a cutting head having at least one cutting member which comprises a main cutting edge and a rake face which adjoins the main cutting edge ; and - a cantilever arm which connects the clamping section to the cutting head and which has a smaller diameter than the clamping section ; wherein the cutting insert is configured in a monolithic manner so that the clamping section , the cutting head and the cantilever arm are integrally connected to each other; characterized in that the cutting member comprises a chip-breaking geometry which protrudes from the rake face or which is introduced into the rake face and which is configured to break a chip which is machined with the main cutting edge , wherein a portion of the cutting head comprising the chip-breaking geometry , when viewed in a plan view from the front side along the longitudinal axis of the cutting insert , covers at least 10% of a cross section of the coolant channel, but a maximum of 80% of the cross section of the coolant channel . - a clamping section which comprises at least one coolant channel which is configured as a through-hole; - a cutting head having at least one cutting member which comprises a main cutting edge and a rake face which adjoins the main cutting edge ; and - a cantilever arm which connects the clamping section to the cutting head and which has a smaller diameter than the clamping section ; wherein the cutting insert is configured in a monolithic manner so that the clamping section , the cutting head and the cantilever arm are integrally connected to each other; characterized in that the cutting member comprises a chip-breaking geometry which protrudes from the rake face or which is introduced into the rake face and which is configured to break a chip which is machined with the main cutting edge , wherein a portion of the cutting head comprising the chip-breaking geometry , when viewed in a plan view from the front side along the longitudinal axis of the cutting insert , covers at least 10% of a cross section of the coolant channel, but a maximum of 80% of the cross section of the coolant channel .
An engineered clostridial toxin, wherein said engineered clostridial toxin is an engineered botulinum neurotoxin A (BoNT/A) comprising: at least one amino acid modification, wherein said at least one amino acid modification comprises substitution of at least one amino acid selected from: N476, S564, N578, E599, L647, D650, D651, V675, I685, N687, T755, E757, N761, N763, 1831, T847, and I849 with lysine or arginine, wherein said at least one amino acid modification increases the isoelectric point (pI) of the engineered clostridial toxin to a value that is at least 0.2 pI units higher than the pI of an otherwise identical clostridial toxin lacking said at least one amino acid modification, and wherein said at least one amino acid modification is not located in the clostridial toxin binding domain (H C domain); and a pI of at least 6.6; and wherein said engineered clostridial toxin: a. is encoded by a nucleic acid sequence having at least 90% sequence identity to a nucleic acid sequence selected from SEQ ID NO: 2, 4, and 6; and/or b. comprises an amino acid sequence having at least 90% sequence identity to an amino acid sequence selected from SEQ ID NO: 1, 3, and 5. at least one amino acid modification, wherein said at least one amino acid modification comprises substitution of at least one amino acid selected from: N476, S564, N578, E599, L647, D650, D651, V675, I685, N687, T755, E757, N761, N763, 1831, T847, and I849 with lysine or arginine, wherein said at least one amino acid modification increases the isoelectric point (pI) of the engineered clostridial toxin to a value that is at least 0.2 pI units higher than the pI of an otherwise identical clostridial toxin lacking said at least one amino acid modification, and wherein said at least one amino acid modification is not located in the clostridial toxin binding domain (H C domain); and a pI of at least 6.6; and a. is encoded by a nucleic acid sequence having at least 90% sequence identity to a nucleic acid sequence selected from SEQ ID NO: 2, 4, and 6; and/or b. comprises an amino acid sequence having at least 90% sequence identity to an amino acid sequence selected from SEQ ID NO: 1, 3, and 5.
A method of making a three-dimensional object, comprising extruding a part material to print layers of the 3D object, wherein the part material comprises a polymeric component selected from the group consisting of: i) at least one poly(ether ether ketone) polymer (PEEK) having a weight average molecular weight (Mw) ranging from 75,000 to 100,000 g/mol, Mw being determined by gel permeation chromatography (GPC) using phenol and trichlorobenzene (1:1) at 160°C, with polystyrene standards, and ii) at least two PEEK polymers having different Mw, the blend thereof having a weight average molecular weight (Mw) ranging from 75,000 to 100,000 g/mol, Mw being determined by gel permeation chromatography (GPC) using phenol and trichlorobenzene (1:1) at 160°C, with polystyrene standards, wherein the PEEK polymer(s) comprises at least 95 mol.% of recurring units (R PEEK ) of formula (J-A), based on the total number of moles in the polymer: where - R', at each location, is independently selected from the group consisting of halogen, alkyl, alkenyl, alkynyl, aryl, ether, thioether, carboxylic acid, ester, amide, imide, alkali or alkaline earth metal sulfonate, alkyl sulfonate, alkali or alkaline earth metal phosphonate, alkyl phosphonate, amine and quaternary ammonium; and - j', for each R', is independently zero or an integer ranging from 1 to 4, and wherein at least 96 mol. % of the recurring units in the PEEK(s) are recurring units (R PEEK ) of formula (J"-A): i) at least one poly(ether ether ketone) polymer (PEEK) having a weight average molecular weight (Mw) ranging from 75,000 to 100,000 g/mol, Mw being determined by gel permeation chromatography (GPC) using phenol and trichlorobenzene (1:1) at 160°C, with polystyrene standards, and ii) at least two PEEK polymers having different Mw, the blend thereof having a weight average molecular weight (Mw) ranging from 75,000 to 100,000 g/mol, Mw being determined by gel permeation chromatography (GPC) using phenol and trichlorobenzene (1:1) at 160°C, with polystyrene standards, - R', at each location, is independently selected from the group consisting of halogen, alkyl, alkenyl, alkynyl, aryl, ether, thioether, carboxylic acid, ester, amide, imide, alkali or alkaline earth metal sulfonate, alkyl sulfonate, alkali or alkaline earth metal phosphonate, alkyl phosphonate, amine and quaternary ammonium; and - j', for each R', is independently zero or an integer ranging from 1 to 4,
A thrust washer (100, 100', 200, 200', 300, 300', 400, 400', 400", 500, 500', 600) for a sliding bearing, comprising a thrust washer substrate having an axial face , and a polymer layer of profiled thickness on the axial face of the substrate , wherein the profiled polymer layer is provided with at least one oil distribution groove , wherein the oil distribution groove comprises a channel and a ramp region , wherein the profiled polymer layer comprises a stacked plurality of polymer sub-layers
A viral vector comprising: a viral capsid comprising a nucleic acid molecule encapsulated within the viral capsid, wherein the nucleic acid molecule comprises: a first nucleic acid sequence that encodes HNF4α; and a second nucleic acid sequence that encodes one or more transcription factors selected from the group consisting of: FOXA1, FOXA2, FOXA3, HNF1α, HNF6, GATA4, HLF, CEBPA, PROX1, and ATF5A; wherein the viral capsid comprises the viral capsid polypeptides VP1 of AAV6, VP2 of AAV6, and VP3 of AAV6. a first nucleic acid sequence that encodes HNF4α; and a second nucleic acid sequence that encodes one or more transcription factors selected from the group consisting of: FOXA1, FOXA2, FOXA3, HNF1α, HNF6, GATA4, HLF, CEBPA, PROX1, and ATF5A; wherein the viral capsid comprises the viral capsid polypeptides VP1 of AAV6, VP2 of AAV6, and VP3 of AAV6.
An extracorporeal focused ultrasound treatment device for a pelvic disease, comprising an ultrasonic transducer and a treatment couch , wherein the ultrasonic transducer comprises a sound emitting surface and a sound generation unit that is configured to generate an ultrasonic wave; the sound emitting surface is a spherical surface having a first notch , a second notch and a third notch , a sphere corresponding to the spherical surface has a diameter in a range of 400 mm to 800 mm, one great circle of the sphere is a main great circle , the first notch and the second notch are respectively positioned at two intersections of the spherical surface and a diameter perpendicular to the main great circle, and the third notch connects the first notch with the second notch; within distances of 100 mm to 200mm from the main great circle respectively at both sides of the main great circle, a cross-section of the sound emitting surface parallel to the main great circle is in a shape of an arc, an opening of the arc corresponds to the third notch, and a central angle corresponding to the arc is larger than 180 degrees and smaller than 300 degrees; and the sound emitting surface is capable of reflecting ultrasound, and an ultrasonic wave generated by the sound generation unit is focused at a center of the sphere corresponding to the sound emitting surface; and the treatment couch is configured for a human body to lie in a lithotomy position, and when the human body lies on the treatment couch in the lithotomy position, a pelvic cavity of the human body is positioned at the center of the sphere corresponding to the sound emitting surface with two legs of the human body respectively sticking out of the sound emitting surface through the first notch and the second notch, and an upper part of the human body sticking out of the sound emitting surface through the third notch.
Electrical vehicle comprising an energy transfer device configured for electrically connecting the electrical vehicle to a charging station , whereby the energy transfer device comprises a lengthwise link and a crosswise link each having an upper end and lower end, characterised in that the lower ends are arranged on the electrical vehicle slidably in crosswise direction of the electrical vehicle , and in that the upper end of the crosswise link is connected to the lengthwise link between its ends such that by sliding the lower ends of the lengthwise link and the crosswise link towards each other the upper end of the lengthwise link is moved away from the electrical vehicle for connecting to the charging station . the energy transfer device comprises a lengthwise link and a crosswise link each having an upper end and lower end, characterised in that the lower ends are arranged on the electrical vehicle slidably in crosswise direction of the electrical vehicle , and in that the upper end of the crosswise link is connected to the lengthwise link between its ends such that by sliding the lower ends of the lengthwise link and the crosswise link towards each other the upper end of the lengthwise link is moved away from the electrical vehicle for connecting to the charging station .
A device comprising: a plurality of first input/output terminals for a projected capacitance touch panel, wherein the projected capacitance touch panel comprises a layer of piezoelectric material disposed between a plurality of sensing electrodes and a common electrode; a plurality of second input/output terminals for a capacitive touch controller; a plurality of separation stages, each separation stage connecting one first input/output terminal to a corresponding second input/output terminal, and each separation stage comprising a first frequency-dependent filter for filtering signals between respective first and second input/output terminals; at least one amplification stage, each amplification stage having at least one input and an output configured to provide an amplified signal, wherein the number of amplification stages is less than or equal to the number of separation stages and each amplification stage input is connected to one or more of the first input/output terminals through the respective separation stage(s); wherein each amplification stage or each separation stage comprises a second frequency-dependent filter for filtering signals between the respective first input/output terminal and an amplification stage input; wherein each first frequency-dependent filter is configured to pass signals from the capacitive touch controller and each second frequency-dependent filter is configured to attenuate signals from the capacitive touch controller. a plurality of first input/output terminals for a projected capacitance touch panel, wherein the projected capacitance touch panel comprises a layer of piezoelectric material disposed between a plurality of sensing electrodes and a common electrode; a plurality of second input/output terminals for a capacitive touch controller; a plurality of separation stages, each separation stage connecting one first input/output terminal to a corresponding second input/output terminal, and each separation stage comprising a first frequency-dependent filter for filtering signals between respective first and second input/output terminals; at least one amplification stage, each amplification stage having at least one input and an output configured to provide an amplified signal, wherein the number of amplification stages is less than or equal to the number of separation stages and each amplification stage input is connected to one or more of the first input/output terminals through the respective separation stage(s); wherein each amplification stage or each separation stage comprises a second frequency-dependent filter for filtering signals between the respective first input/output terminal and an amplification stage input; wherein each first frequency-dependent filter is configured to pass signals from the capacitive touch controller and each second frequency-dependent filter is configured to attenuate signals from the capacitive touch controller.
An implantable rate responsive pacemaker , comprising: a sensor module configured to produce an activity signal correlated to a metabolic demand of a patient and a posture signal correlated to patient posture; a pulse generator configured to generate and deliver pacing pulses to a patient's heart via a pair of electrodes coupled to the pacemaker; and a control module coupled to the pulse generator and the sensor module and configured to: determine a sensor indicated pacing rate from the activity signal; compare the posture signal to verification criteria for confirming an exercising posture of the patient; and withhold an adjustment of a pacing rate to the sensor indicated pacing rate responsive to the verification criteria not being met, wherein the control module is further configured to: compare the sensor indicated pacing rate to a rate threshold, and compare the posture signal to the verification criteria only in response to the sensor indicated pacing rate being greater than the rate threshold. a sensor module configured to produce an activity signal correlated to a metabolic demand of a patient and a posture signal correlated to patient posture; a pulse generator configured to generate and deliver pacing pulses to a patient's heart via a pair of electrodes coupled to the pacemaker; and a control module coupled to the pulse generator and the sensor module and configured to: determine a sensor indicated pacing rate from the activity signal; compare the posture signal to verification criteria for confirming an exercising posture of the patient; and withhold an adjustment of a pacing rate to the sensor indicated pacing rate responsive to the verification criteria not being met, wherein the control module is further configured to: compare the sensor indicated pacing rate to a rate threshold, and compare the posture signal to the verification criteria only in response to the sensor indicated pacing rate being greater than the rate threshold. determine a sensor indicated pacing rate from the activity signal; compare the posture signal to verification criteria for confirming an exercising posture of the patient; and withhold an adjustment of a pacing rate to the sensor indicated pacing rate responsive to the verification criteria not being met, wherein the control module is further configured to: compare the sensor indicated pacing rate to a rate threshold, and compare the posture signal to the verification criteria only in response to the sensor indicated pacing rate being greater than the rate threshold.
A lawn mower , comprising: a housing ; a walking mechanism , supporting the housing and driving the housing to walk, and comprising a drive wheel ; a motor , mounted at the housing , and used to drive the drive wheel to rotate; and a control apparatus ; characterized in that the control apparatus is preset with a first torque threshold and a second torque threshold, wherein as the at least one motor is switched from a stopped state to a running state, the control apparatus controls a difference between a maximum actual output torque of the at least one motor and the first torque threshold to be within a predetermined range, when the motor is in the running state, the control apparatus controls an actual output torque of the at least one motor to at most increase to the second torque threshold, the first torque threshold is less than or equal to a maximum output torque of the motor , and the second torque threshold is less than the first torque threshold. a housing ; a walking mechanism , supporting the housing and driving the housing to walk, and comprising a drive wheel ; a motor , mounted at the housing , and used to drive the drive wheel to rotate; and a control apparatus ; characterized in that the control apparatus is preset with a first torque threshold and a second torque threshold, wherein as the at least one motor is switched from a stopped state to a running state, the control apparatus controls a difference between a maximum actual output torque of the at least one motor and the first torque threshold to be within a predetermined range, when the motor is in the running state, the control apparatus controls an actual output torque of the at least one motor to at most increase to the second torque threshold, the first torque threshold is less than or equal to a maximum output torque of the motor , and the second torque threshold is less than the first torque threshold.
A method for separating a wafer comprising a growth substrate and a plurality of devices formed on the growth substrate and arranged in at least two rows separated by at least one street(s) , the wafer comprising a front side on which the plurality of devices are formed and a back side comprising a surface of the growth substrate , the method comprising: scribing a first scribe line aligned with a first street from the at least one street(s) on the front side ; scribing a second scribe line aligned with the first street on the back side , comprising forming a first modified region within the growth substrate ; and scribing a third scribe line aligned with the first street on the back side , wherein scribing the third scribe line comprises forming a second modified region within the growth substrate ; and the first modified region is at a different depth in the growth substrate than the second modified region. scribing a first scribe line aligned with a first street from the at least one street(s) on the front side ; scribing a second scribe line aligned with the first street on the back side , comprising forming a first modified region within the growth substrate ; and scribing a third scribe line aligned with the first street on the back side , wherein scribing the third scribe line comprises forming a second modified region within the growth substrate ; and the first modified region is at a different depth in the growth substrate than the second modified region.
A blade cartridge for use with a produce slicer frame for the purpose of slicing produce, the blade cartridge comprising a blade assembly , comprising first and second blade sets stacked upon one another, the first and second blade sets each comprising a first frame bar and a second frame bar , and a plurality of blades extending therebetween; characterized in that the blade assembly comprises a blade cover having a planar top portion , and the stacked first and second blade sets are secured to the blade cover, such that the plurality of blades of the first blade set is at a different orientation than an orientation of the plurality of blades of the second blade set , for simultaneous insertion of the blade assembly comprising the blade cover and the blade sets into the produce slicer frame. a blade assembly , comprising first and second blade sets stacked upon one another, the first and second blade sets each comprising a first frame bar and a second frame bar , and a plurality of blades extending therebetween; characterized in that the blade assembly comprises a blade cover having a planar top portion , and the stacked first and second blade sets are secured to the blade cover, such that the plurality of blades of the first blade set is at a different orientation than an orientation of the plurality of blades of the second blade set , for simultaneous insertion of the blade assembly comprising the blade cover and the blade sets into the produce slicer frame.
A resin composition obtained by polymerizing a polymerizable composition including a polyisocyanate compound and a polythiol compound, wherein the polymerizable composition includes a dye L having an absorption maximum wavelength of 550 nm or more and 600 nm or less in a toluene solution of 20 ppm by mass, and a dye S having an absorption maximum wavelength of 500 nm or more and less than 550 nm in a toluene solution of 20 ppm by mass, and a mass ratio [(mass of dye L)/(mass of dye S)] of the dye L to the dye S is 5 or more and 500 or less.
A method for the control of a driving speed (v F ) of an agricultural machine , in particular, of an agricultural towing machine or self-propelled work machine, which is equipped at a driving position with at least an accelerator pedal and a brake pedal for foot actuation as well as with at least one hand lever , wherein the pedals and the hand lever each serve to influence the driving speed (v F ) by corresponding drive commands from the machine operator, characterised in that the in each case most recently carried out actuation of one of the foot pedals or of the hand lever by the machine operator with a change request of the driving speed (v F ) defines the in each case active actuation mode for hand control or foot control, and suppresses a connection of the travel speed control to the respective other actuation mode for at least as long as a changed request is carried out by the machine operator by corresponding actuation by means of stepping on and/or releasing one of the foot pedals or by means of pressing the hand lever , and wherein an actuation of one of the foot pedals or of the hand lever with a simultaneously carried out defined position change is interpreted as change request, which determines whether the foot pedals or the hand lever form the respectively active actuation element.