A compound of the formula: or a pharmacologically acceptable salt, stereoisomer, diastereomer, enantiomer, racemate, hydrate and/or solvate thereof, wherein: B is: (i) selected from the group consisting of: and R 1 , R 3 and R 4 are independently CH, CH 2 , O, N, NH or S, R 2 is CH, CH 2 , N, NH, C-CF 3 , CH-CF 3 or C=O; Q is selected from amino and substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; or (ii) Q is substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; D is selected from the group consisting of: T is selected from hydrogen, C 1-6 alkyl, halo, C 0-6 alkyl carboxylic acid, amino, hydroxy and C 1-6 alkoxy; and m is 1 or 2, wherein D cannot be unsubstituted phenyl. B is: (i) selected from the group consisting of: and R 1 , R 3 and R 4 are independently CH, CH 2 , O, N, NH or S, R 2 is CH, CH 2 , N, NH, C-CF 3 , CH-CF 3 or C=O; Q is selected from amino and substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; or (ii) Q is substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; (i) selected from the group consisting of: and R 1 , R 3 and R 4 are independently CH, CH 2 , O, N, NH or S, R 2 is CH, CH 2 , N, NH, C-CF 3 , CH-CF 3 or C=O; Q is selected from amino and substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; or R 1 , R 3 and R 4 are independently CH, CH 2 , O, N, NH or S, R 2 is CH, CH 2 , N, NH, C-CF 3 , CH-CF 3 or C=O; Q is selected from amino and substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; (ii) Q is substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; Q is substituted amino of the formula -NHW wherein: W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and W is selected from -CN, -SO 2 (X 1 ) a Y and -CO(X 1 ) a Y, a is 0 or 1, X 1 is selected from -NH- and -O-, and Y is selected from -H, -CH 3 , -CH 2 CH 3 , -CH 2 OH and -CH 2 CH 2 OH; and n is 1 or 2; D is selected from the group consisting of: T is selected from hydrogen, C 1-6 alkyl, halo, C 0-6 alkyl carboxylic acid, amino, hydroxy and C 1-6 alkoxy; and m is 1 or 2, wherein D cannot be unsubstituted phenyl. <EOS>