mhurhangee/patent-ind-claim-en huggingface dataset:
A method for operating an LED series with pulse-modulated pulses, wherein during the switch-on time period of a PM-pulse an energy store (L1, L2) is charged by closing a switch (S1) and when the switch is opened the energy store is discharged via the LED series, so that a cyclically increasing and decreasing current flow through the LED series results, wherein the switch (S1) is switched on, if a lower switch-on threshold of the LED current or a specific switch-off time is achieved, wherein - the time constant, therefore the time period of the increasing and/or the decreasing phase of the current flow through the LED series is continuously or discretely changed depending on the state, characterized in that - the time constants of the energy store are changed, wherein the energy store has at least one inductor (L1, L2), and the clock frequency of the switch (S1) is changed by a corresponding variation of the inductance value of the inductor (L1, L2). - the time constant, therefore the time period of the increasing and/or the decreasing phase of the current flow through the LED series is continuously or discretely changed depending on the state, characterized in that - the time constants of the energy store are changed, wherein the energy store has at least one inductor (L1, L2), and the clock frequency of the switch (S1) is changed by a corresponding variation of the inductance value of the inductor (L1, L2).
An in vitro method for fusing two or more cells comprising: - contacting a first cell with a second cell to form a third cell; wherein - the first cell is a modified cell comprising a myomerger nucleic acid, a first myomerger polypeptide, and a first myomaker polypeptide; wherein the first cell is a non-muscle cell; - the second cell comprises a second myomaker polypeptide and optionally comprises a second myomerger polypeptide; - the third cell is a multinucleated cell; - the myomerger nucleic acid sequence encodes a polypeptide comprising the first myomerger polypeptide and has at least an 80% identity to one or more of SEQ ID NO: 43, SEQ ID NO: 44, or SEQ ID NO: 45,; and - the first myomerger polypeptide sequence and the second myomerger polypeptide sequence each have at least an 80% identity to one or more of SEQ ID NO: 36, SEQ ID NO: 37, and SEQ ID NO: 38. - contacting a first cell with a second cell to form a third cell; wherein - the first cell is a modified cell comprising a myomerger nucleic acid, a first myomerger polypeptide, and a first myomaker polypeptide; wherein the first cell is a non-muscle cell; - the second cell comprises a second myomaker polypeptide and optionally comprises a second myomerger polypeptide; - the third cell is a multinucleated cell; - the myomerger nucleic acid sequence encodes a polypeptide comprising the first myomerger polypeptide and has at least an 80% identity to one or more of SEQ ID NO: 43, SEQ ID NO: 44, or SEQ ID NO: 45,; and - the first myomerger polypeptide sequence and the second myomerger polypeptide sequence each have at least an 80% identity to one or more of SEQ ID NO: 36, SEQ ID NO: 37, and SEQ ID NO: 38.
A hollow body , comprising a wall which at least partially surrounds an interior volume of the hollow body ; wherein the wall a) comprises a layer of glass , and b) has a wall surface ; wherein the wall surface comprises a surface region which is characterised by a contact angle for wetting with water of at least 80°. a) comprises a layer of glass , and b) has a wall surface ;
A medicinal fluid injection device comprising: a housing having an opening in a side surface thereof; a storage container arranged inside the housing and storing a medicinal fluid; an injection needle fluidly connected to the storage container and injecting the medicinal fluid through the opening ; a pump arranged inside the housing ; a frame coupled to the housing and having a hole corresponding to the opening ; a cover part (210, 210', 210") positioned on a side of the frame ; and an auxiliary cover part positioned opposite the cover part (210, 210', 210") with the hole between the auxiliary cover part and the cover part (210, 210', 210"); wherein a space is formed between the cover part (210, 210', 210") and the auxiliary cover part , the space being fluidly connected to the injection needle as the injection needle passes through the auxiliary cover part ; and wherein air in the injection needle is discharged toward the space by a movement of the medical fluid which is moved by the pump , and wherein at least one of the cover part or the auxiliary cover part comprises a polymer, the polymer comprising natural rubber, synthetic rubber or a silicone-based polymer. a housing having an opening in a side surface thereof; a storage container arranged inside the housing and storing a medicinal fluid; an injection needle fluidly connected to the storage container and injecting the medicinal fluid through the opening ; a pump arranged inside the housing ; a frame coupled to the housing and having a hole corresponding to the opening ; a cover part (210, 210', 210") positioned on a side of the frame ; and an auxiliary cover part positioned opposite the cover part (210, 210', 210") with the hole between the auxiliary cover part and the cover part (210, 210', 210"); wherein a space is formed between the cover part (210, 210', 210") and the auxiliary cover part , the space being fluidly connected to the injection needle as the injection needle passes through the auxiliary cover part ; and wherein air in the injection needle is discharged toward the space by a movement of the medical fluid which is moved by the pump , and wherein at least one of the cover part or the auxiliary cover part comprises a polymer, the polymer comprising natural rubber, synthetic rubber or a silicone-based polymer.
A composition comprising ajulemic acid for use in treating lung fibrosis in a subject.
A system comprising: a compressor including a compression mechanism and a motor ; a first heat exchanger receiving compressed working fluid from said compressor ; an expansion device disposed downstream of said first heat exchanger ; a first working fluid flow path fluidly connecting said first heat exchanger and said expansion device ; a second working fluid flow path disposed downstream of said first heat exchanger , characterized by the second working fluid flow path fluidly connecting said first heat exchanger with a first inlet of said compressor and providing compressed working fluid through said first inlet to said compression mechanism and to said motor , said first inlet being fluidly isolated from a compression chamber of said compressor ; and a pump disposed between said first heat exchanger and said expansion device . a compressor including a compression mechanism and a motor ; a first heat exchanger receiving compressed working fluid from said compressor ; an expansion device disposed downstream of said first heat exchanger ; a first working fluid flow path fluidly connecting said first heat exchanger and said expansion device ; a second working fluid flow path disposed downstream of said first heat exchanger , characterized by the second working fluid flow path fluidly connecting said first heat exchanger with a first inlet of said compressor and providing compressed working fluid through said first inlet to said compression mechanism and to said motor , said first inlet being fluidly isolated from a compression chamber of said compressor ; and a pump disposed between said first heat exchanger and said expansion device .
A telescoping boom comprising: a boom actuator having a fixed part and a movable part ; a rotary actuator operably connected to the movable part and rotatable relative thereto; a coupling pin connected to and configured to rotate with the rotary actuator ; a plurality of boom sections including a base section and one or more telescoping sections configured for telescoping movement along a longitudinal boom axis (A1) relative to the base section ; characterized by a rotary extension and locking system mounted to at least one telescoping section , the rotary extension and locking system comprising a coupling ring rotatably mounted on the telescoping section ; a section pin operably connected to the coupling ring ; and a latch configured to selectively engage the section pin , the rotary extension and locking system being configured for selective coupling to the boom actuator as the rotary actuator rotates the coupling pin into engagement with the coupling ring , and for selective locking with a nearest outwardly adjacent boom section as the rotary actuator rotates the coupling ring to move the section pin from a a second position (P2) to a first position (P1). a boom actuator having a fixed part and a movable part ; a rotary actuator operably connected to the movable part and rotatable relative thereto; a coupling pin connected to and configured to rotate with the rotary actuator ; a plurality of boom sections including a base section and one or more telescoping sections configured for telescoping movement along a longitudinal boom axis (A1) relative to the base section ; characterized by a rotary extension and locking system mounted to at least one telescoping section , the rotary extension and locking system comprising a coupling ring rotatably mounted on the telescoping section ; a section pin operably connected to the coupling ring ; and a latch configured to selectively engage the section pin , the rotary extension and locking system being configured for selective coupling to the boom actuator as the rotary actuator rotates the coupling pin into engagement with the coupling ring , and for selective locking with a nearest outwardly adjacent boom section as the rotary actuator rotates the coupling ring to move the section pin from a a second position (P2) to a first position (P1).
An injection molding apparatus comprising: a barrel ; a nozzle enclosing an end of the barrel and defining a nozzle tip portion with an opening in fluid communication with an inside of the barrel ; and an extrusion screw positioned at least partially inside the barrel and rotatable relative to the barrel , the extrusion screw including a screw tip configured to prevent formation of a cold slug in the opening of the nozzle ; wherein relative axial movement between the barrel and the extrusion screw opens or closes the opening of the nozzle tip portion to permit or prevent, respectively, material flow through the opening of the nozzle tip portion ; and wherein the screw tip comprises: a screw tip portion ; a non-threaded cylindrical portion ; and an angled transition portion connecting the screw tip portion to the non-threaded cylindrical portion ; and wherein the screw tip portion is shaped to match the geometry of the opening of the nozzle tip portion ; characterized in that the angled transition portion is shaped to match the geometry of an inner surface of a side wall of the nozzle tip portion such that the screw tip is configured to seal the opening in the nozzle tip portion . a barrel ; a nozzle enclosing an end of the barrel and defining a nozzle tip portion with an opening in fluid communication with an inside of the barrel ; and an extrusion screw positioned at least partially inside the barrel and rotatable relative to the barrel , the extrusion screw including a screw tip configured to prevent formation of a cold slug in the opening of the nozzle ; wherein relative axial movement between the barrel and the extrusion screw opens or closes the opening of the nozzle tip portion to permit or prevent, respectively, material flow through the opening of the nozzle tip portion ; and wherein the screw tip comprises: a screw tip portion ; a non-threaded cylindrical portion ; and an angled transition portion connecting the screw tip portion to the non-threaded cylindrical portion ; and a screw tip portion ; a non-threaded cylindrical portion ; and an angled transition portion connecting the screw tip portion to the non-threaded cylindrical portion ; and wherein the screw tip portion is shaped to match the geometry of the opening of the nozzle tip portion ; characterized in that the angled transition portion is shaped to match the geometry of an inner surface of a side wall of the nozzle tip portion such that the screw tip is configured to seal the opening in the nozzle tip portion .
An arc welding method comprising: performing pulse arc welding with a welding wire being fed in a forward direction during a first period; performing short-circuit transfer arc welding with the welding wire being fed in the forward direction and a reverse direction during a second period; alternately switching between the first period and the second period; wherein switching the first period to the second period is performed in a manner such that no transfer of a molten droplet of the welding wire occurs during a final pulse cycle of the first period; wherein the forward-feeding peak value in a first cycle of the second period is set to be different from the forward-feeding peak value in a subsequent cycle of the second period; characterized by increasing a feeding speed (Fw) of the welding wire to a forward-feeding peak value (Wsp) continuously from a start of the second period, and maintaining the feeding speed at the forward-feeding peak value until short-circuiting occurs for a first time thereafter. performing pulse arc welding with a welding wire being fed in a forward direction during a first period; performing short-circuit transfer arc welding with the welding wire being fed in the forward direction and a reverse direction during a second period; alternately switching between the first period and the second period; wherein switching the first period to the second period is performed in a manner such that no transfer of a molten droplet of the welding wire occurs during a final pulse cycle of the first period; wherein the forward-feeding peak value in a first cycle of the second period is set to be different from the forward-feeding peak value in a subsequent cycle of the second period; characterized by increasing a feeding speed (Fw) of the welding wire to a forward-feeding peak value (Wsp) continuously from a start of the second period, and maintaining the feeding speed at the forward-feeding peak value until short-circuiting occurs for a first time thereafter.
An NMR-MAS probehead having an MAS stator for receiving an elongate MAS rotor that is surrounded by an RF coil , said MAS rotor having a sample substance in a sample volume , and having a hollow, elongate first microwave guide for supplying microwave radiation into the sample volume through a coil block introduced in a wall of the MAS stator , characterized in that the coil block is designed in accordance with any one of the claims 11 to 15 and has such a geometric extent and is inserted into the wall of the MAS stator in such a way that it at least partly surrounds the RF coil and the MAS rotor .
Rotor nozzle, having a carrier element which has an axial bore for supplying a pressurized liquid, a nozzle head which is rotatably mounted thereon and can be driven in rotation by a hydraulically generated torque, which has at least one laterally emerging removal nozzle which is connected to the axial bore in a fluid-open manner, the removal nozzle being radially aligned and the nozzle head having at least one laterally emerging, separate drive nozzle , which extends at a distance (A) from the radial (R), characterized in that the at least one drive nozzle is connected to the axial bore via a through bore of the support element , depending on the rotational position of the nozzle head , so that the at least one drive nozzle is briefly fed with the liquid under high pressure by bringing the through bore connected to the axial bore into alignment with the inlet of the at least one drive nozzle .
An air conditioning system comprising: an intake unit configured to take in return air (RA) of an indoor space (IS) from a ceiling (CE) of the indoor space (IS); an outdoor air processing unit ; an air conditioner ; and a plurality of radiation units , wherein the outdoor air processing unit is connected to the intake unit via a first duct , and the outdoor air processing unit is configured to supply outdoor air (OA) while exhausting part of the return air (RA) taken in via the intake unit to outdoors, the air conditioner is connected to the intake unit via a second duct and connected to the outdoor air processing unit via a third duct , and the air conditioner is configured to supply, as air-conditioning air, mixed air of the other part of the return air (RA) taken in via the intake unit and the outdoor air (OA) supplied by the outdoor air processing unit , the plurality of radiation units are connected to the air conditioner and disposed in a manner to surround the intake unit , and the plurality of radiation units are configured to radiate heat of the air-conditioning air supplied by the air conditioner while discharging the air-conditioning air to the indoor space (IS), and the air conditioning system is configured to air-condition the indoor space (IS) so as to radiate the heat from the plurality of radiation units while generating an induced air stream in the intake unit to ventilate the indoor space (IS). an intake unit configured to take in return air (RA) of an indoor space (IS) from a ceiling (CE) of the indoor space (IS); an outdoor air processing unit ; an air conditioner ; and a plurality of radiation units , wherein the outdoor air processing unit is connected to the intake unit via a first duct , and the outdoor air processing unit is configured to supply outdoor air (OA) while exhausting part of the return air (RA) taken in via the intake unit to outdoors, the air conditioner is connected to the intake unit via a second duct and connected to the outdoor air processing unit via a third duct , and the air conditioner is configured to supply, as air-conditioning air, mixed air of the other part of the return air (RA) taken in via the intake unit and the outdoor air (OA) supplied by the outdoor air processing unit , the plurality of radiation units are connected to the air conditioner and disposed in a manner to surround the intake unit , and the plurality of radiation units are configured to radiate heat of the air-conditioning air supplied by the air conditioner while discharging the air-conditioning air to the indoor space (IS), and the air conditioning system is configured to air-condition the indoor space (IS) so as to radiate the heat from the plurality of radiation units while generating an induced air stream in the intake unit to ventilate the indoor space (IS).
An immunogenic composition comprising i. a Staphylococcus aureus Type 5 capsular saccharide conjugated to a carrier protein to form a S. aureus Type 5 capsular saccharide conjugate, wherein the S. aureus Type 5 capsular saccharide conjugate is administered at a saccharide dose of 3-50 μg, 5-25 μg, 3-20 μg, 3-12 μg, 5-10 μg, 7-20 μg, 7-15 μg or 8-12 μg, and ii. a S. aureus Type 8 capsular saccharide conjugated to a carrier protein to form a S. aureus Type 8 capsular saccharide conjugate, wherein the S. aureus Type 8 capsular saccharide conjugate is administered at a saccharide dose of 3-50 μg, 5-25 μg, 3-20 μg, 3-12 μg, 5-10 μg, 7-20 μg, 7-15 μg or 8-12 μg, and iii. a ClfA protein or fragment thereof wherein the ClfA protein or fragment thereof is at least 90% identical to the polypeptide sequence of any one of SEQ ID NO: 3-12 or 15-18 along the full length thereof, and iv. an alpha toxoid for use in treatment or prevention of Staphylococcus aureus infection in which a human patient is immunised with a single dose of the immunogenic composition. i. a Staphylococcus aureus Type 5 capsular saccharide conjugated to a carrier protein to form a S. aureus Type 5 capsular saccharide conjugate, wherein the S. aureus Type 5 capsular saccharide conjugate is administered at a saccharide dose of 3-50 μg, 5-25 μg, 3-20 μg, 3-12 μg, 5-10 μg, 7-20 μg, 7-15 μg or 8-12 μg, and ii. a S. aureus Type 8 capsular saccharide conjugated to a carrier protein to form a S. aureus Type 8 capsular saccharide conjugate, wherein the S. aureus Type 8 capsular saccharide conjugate is administered at a saccharide dose of 3-50 μg, 5-25 μg, 3-20 μg, 3-12 μg, 5-10 μg, 7-20 μg, 7-15 μg or 8-12 μg, and iii. a ClfA protein or fragment thereof wherein the ClfA protein or fragment thereof is at least 90% identical to the polypeptide sequence of any one of SEQ ID NO: 3-12 or 15-18 along the full length thereof, and iv. an alpha toxoid
A hemostatic composition in powder form comprising: - collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, said collagen being in a content ranging from 70% to 99% by weight relative to the total weight of the composition, - at least one monosaccharide in a content ranging from 1% to 12.5% by weight relative to the total weight of the composition, and - at least one coagulation factor in a content ranging from 0.01 IU/mg to 20 IU/mg. - collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, said collagen being in a content ranging from 70% to 99% by weight relative to the total weight of the composition, - at least one monosaccharide in a content ranging from 1% to 12.5% by weight relative to the total weight of the composition, and - at least one coagulation factor in a content ranging from 0.01 IU/mg to 20 IU/mg.
Operating device having - a base element , - a transceiver, which is arranged fixedly on the base element , for emitting and receiving light , - an operating element , which is movable with respect to the base element between a first extreme position and a second extreme position , and - an optical element which is arranged fixedly at the operating element , for deflecting the light of the transceiver, wherein - the light of the transceiver is focusable substantially towards a receiving part of the transceiver by the optical element and - an evaluation apparatus of the operating device, for evaluating a signal of the receiving part , is formed in such a way that an intensity of the received light , which is represented by the signal, is assigned to a position of the operating element in a range from the first extreme position to the second extreme position , characterized in that - the optical element is designed asymmetrically in such a way and the light emitted by the transceiver is directed to the optical element in such a way that, when the operating element moves in an actuating direction , a focal point moves with a movement component perpendicular to this actuating direction . - a base element , - a transceiver, which is arranged fixedly on the base element , for emitting and receiving light , - an operating element , which is movable with respect to the base element between a first extreme position and a second extreme position , and - an optical element which is arranged fixedly at the operating element , for deflecting the light of the transceiver, - the light of the transceiver is focusable substantially towards a receiving part of the transceiver by the optical element and - an evaluation apparatus of the operating device, for evaluating a signal of the receiving part , is formed in such a way that an intensity of the received light , which is represented by the signal, is assigned to a position of the operating element in a range from the first extreme position to the second extreme position , - the optical element is designed asymmetrically in such a way and the light emitted by the transceiver is directed to the optical element in such a way that, when the operating element moves in an actuating direction , a focal point moves with a movement component perpendicular to this actuating direction .