mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of Formula (I) for use in a method of treating autism spectrum disorder in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of compound of Formula (I), wherein X is CH 2 or O; Y is R 1 is H; R 2a and R 2b are each H; R 3 is 2,3-dihydro-1H-indene; pyridyl substituted with C 1-6 alkyl; phenyl; or phenyl substituted with one or two members each independently selected from the group consisting of: halo, C 1-6 alkyl, C 1-6 alkyl substituted with OH, C 1-6 alkyl substituted with CO 2 H, C 1-6 haloalkyl, OC 1-6 haloalkyl, C 3-6 cycloalkyl, O-phenyl, and C 3-6 cycloalkyl substituted with CH 3 ; R a and R b are each independently H or halo; and R c is H or CH 3 ; or a pharmaceutically acceptable salt, isotope, N-oxide, solvate, or stereoisomer thereof. X is CH 2 or O; Y is R 1 is H; R 2a and R 2b are each H; R 3 is 2,3-dihydro-1H-indene; pyridyl substituted with C 1-6 alkyl; phenyl; or phenyl substituted with one or two members each independently selected from the group consisting of: halo, C 1-6 alkyl, C 1-6 alkyl substituted with OH, C 1-6 alkyl substituted with CO 2 H, C 1-6 haloalkyl, OC 1-6 haloalkyl, C 3-6 cycloalkyl, O-phenyl, and C 3-6 cycloalkyl substituted with CH 3 ; R a and R b are each independently H or halo; and R c is H or CH 3 ;
A medical device for surgical breast procedures, comprising: a sheet-like sample of biocompatible material , wherein the sample of biocompatible material includes a first edge and a second edge , wherein the first edge and the second edge are joined at a first apex and a second apex , and wherein the first edge includes a convex portion that curves away from the second edge and the second edge includes a convex portion that curves away from the first edge ; characterised in that : the first edge is substantially parabolicly curved, having a focus and a vertex separated by a first length; the second edge is substantially parabolicly curved, having a focus and a vertex separated by a second length; and the second length is greater than the first length.
An auxiliary system for a low-temperature remote thermal energy distribution network (anergy network) connected to user thermal installations, the auxiliary system comprising a heat exchanger and one or more heat pumps thermally coupled to the anergy network via said heat exchanger , the auxiliary system also comprising one or more air-liquid heat exchangers thermally coupled to the outside air, and a hydraulic network interconnecting the heat pumps to the heat exchanger , at least one of the heat pumps being a liquid-air heat pump fluidically connected by the hydraulic network to at least one of said air-liquid heat exchangers , the auxiliary system further comprising a measurement, control and regulation (MCR) system , characterized in that the hydraulic network comprises valves controlled by the MCR system and a hydraulic circuit configured to allow direct connection of said air-liquid heat exchangers to the heat exchanger .
Sealing device for a turbomachine , notably a turbomachine compressor , the device comprising: - a stator shroud intended to be fixed to the radial ends of stator blades ; - a rotor with a brush seal (42; 44) arranged inside the shroud ; characterized in that the shroud comprises a frustoconical internal surface (54; 56) the profile of which is substantially inclined with respect to the bristles of the brush seal (42; 44) so as to seal with the said brush seal (42; 44). - a stator shroud intended to be fixed to the radial ends of stator blades ; - a rotor with a brush seal (42; 44) arranged inside the shroud ; characterized in that
A spot light apparatus, comprising: a light source plate mounted with a color module and a white light module in a central area of the light source plate , the color module having LED chips of multiple colors integrated in a package; a driver configured for converting an external power source to an internal power source; a control module , electrically connected to the driver and configured for controlling the color module and the white light module to emit a mixed light; and a lens module having an inner central lens , a surrounding lens , an outer central lens , and a main light output side , the inner central lens refracting the mixed light to the main light output side , the surrounding lens reflecting the mixed light to the main light output side , the outer central lens further mixing sub-lights from the color module and the white light module , the inner central lens being aligned with the central part of the light source plate and being disposed above the color module and the white light module , the spot light apparatus further comprising a light housing with a bowl potion and a neck portion , the lens module being installed to the bowl portion and defining a peripheral space , a portion of the control module being kept in the peripheral space , characterized in that : the control module is plugged to the driver and extended with a tilt angle toward the peripheral space . a light source plate mounted with a color module and a white light module in a central area of the light source plate , the color module having LED chips of multiple colors integrated in a package; a driver configured for converting an external power source to an internal power source; a control module , electrically connected to the driver and configured for controlling the color module and the white light module to emit a mixed light; and a lens module having an inner central lens , a surrounding lens , an outer central lens , and a main light output side , the inner central lens refracting the mixed light to the main light output side , the surrounding lens reflecting the mixed light to the main light output side , the outer central lens further mixing sub-lights from the color module and the white light module , the inner central lens being aligned with the central part of the light source plate and being disposed above the color module and the white light module , the spot light apparatus further comprising a light housing with a bowl potion and a neck portion , the lens module being installed to the bowl portion and defining a peripheral space , a portion of the control module being kept in the peripheral space , characterized in that : the control module is plugged to the driver and extended with a tilt angle toward the peripheral space .
A method for forming a low-k dielectric material selectively on a first area of a top surface of a substrate, comprising: a. providing the substrate comprising the top surface, the top surface comprising the first area and a second area , the first area having a hydrophilicity characterized by a water contact angle of at least 45° and the second area having a hydrophilicity characterized by a water contact angle of less than 40°, b. providing a precursor aqueous solution on the substrate, the precursor aqueous solution comprising: - a solvent, - a dielectric material precursor, - a catalyst for forming a dielectric material from the dielectric material precursor, and - an ionic surfactant , c. removing the solvent, and c'. after step c or simultaneous with step c, removing the ionic surfactant from the dielectric material , thereby forming the low-k dielectric material; wherein step b of providing the precursor aqueous solution on the substrate comprises spin coating the aqueous solution on the substrate, and wherein the low-k dielectric material comprises silica or an organosilica. a. providing the substrate comprising the top surface, the top surface comprising the first area and a second area , the first area having a hydrophilicity characterized by a water contact angle of at least 45° and the second area having a hydrophilicity characterized by a water contact angle of less than 40°, b. providing a precursor aqueous solution on the substrate, the precursor aqueous solution comprising: - a solvent, - a dielectric material precursor, - a catalyst for forming a dielectric material from the dielectric material precursor, and - an ionic surfactant , - a solvent, - a dielectric material precursor, - a catalyst for forming a dielectric material from the dielectric material precursor, and - an ionic surfactant , c. removing the solvent, and c'. after step c or simultaneous with step c, removing the ionic surfactant from the dielectric material , thereby forming the low-k dielectric material; wherein step b of providing the precursor aqueous solution on the substrate comprises spin coating the aqueous solution on the substrate, and wherein the low-k dielectric material comprises silica or an organosilica. c'. after step c or simultaneous with step c, removing the ionic surfactant from the dielectric material , thereby forming the low-k dielectric material; wherein step b of providing the precursor aqueous solution on the substrate comprises spin coating the aqueous solution on the substrate, and wherein the low-k dielectric material comprises silica or an organosilica.
Electromechanical motor vehicle steering system comprising a steering gear housing , a steering rod which is arranged in an axially movable fashion in the steering gear housing and is axially displaceable by means of a driver-side steering handle , wherein the axial travel of the steering rod is limited, an electric motor which is coupled to the steering rod for the purpose of axially displacing the steering rod, and a damping element for the steering rod which, in a deenergized state of the motor vehicle steering system , forms an axial end stop against an axial force and thus limits the maximum steering angle in the deenergized state, characterized in that the elasticity of the damping element is adapted to the electric motor and the electric motor is configured in such a way that, in the energized state of the motor vehicle steering system, the said axial end stop can be overridden by further compression of the damping element by the axial force applied by the electric motor , so that, in the deenergized state, limiting of the axial travel of the steering rod by at the axial end stop occurs a smaller axial travel than in the energized state of the motor vehicle steering system . a steering gear housing , a steering rod which is arranged in an axially movable fashion in the steering gear housing and is axially displaceable by means of a driver-side steering handle , wherein the axial travel of the steering rod is limited, an electric motor which is coupled to the steering rod for the purpose of axially displacing the steering rod, and a damping element for the steering rod which, in a deenergized state of the motor vehicle steering system , forms an axial end stop against an axial force and thus limits the maximum steering angle in the deenergized state, characterized in that the elasticity of the damping element is adapted to the electric motor and the electric motor is configured in such a way that, in the energized state of the motor vehicle steering system, the said axial end stop can be overridden by further compression of the damping element by the axial force applied by the electric motor , so that, in the deenergized state, limiting of the axial travel of the steering rod by at the axial end stop occurs a smaller axial travel than in the energized state of the motor vehicle steering system .
Sewer inspection and/or maintenance device , having - a housing , - a sensor device which is arranged in the housing and has at least one sensor element , and - a cleaning device for cleaning at least part of the sensor device , wherein the cleaning device has: - a pressure chamber for receiving a pressurized gas, wherein the pressure chamber is arranged outside the housing and comprises a pressure bottle, - at least one nozzle having an outlet opening which is or can be aligned toward the part of the sensor device to be cleaned, and - a valve which is operatively arranged between the pressure chamber and the nozzle in order to control the application of the gas to the part of the sensor device to be cleaned, wherein - the at least one nozzle is arranged outside the housing and is designed to be pivotable in order to change the angle of the gas outlet channel of the nozzle relative to the part of the sensor device to be cleaned, and/or - the sensor device is articulated pivotably on the sewer inspection and/or maintenance device in order to align the part of the sensor device to be cleaned with the outlet opening of the nozzle. - a housing , - a sensor device which is arranged in the housing and has at least one sensor element , and - a cleaning device for cleaning at least part of the sensor device , - a pressure chamber for receiving a pressurized gas, wherein the pressure chamber is arranged outside the housing and comprises a pressure bottle, - at least one nozzle having an outlet opening which is or can be aligned toward the part of the sensor device to be cleaned, and - a valve which is operatively arranged between the pressure chamber and the nozzle in order to control the application of the gas to the part of the sensor device to be cleaned, - the at least one nozzle is arranged outside the housing and is designed to be pivotable in order to change the angle of the gas outlet channel of the nozzle relative to the part of the sensor device to be cleaned, and/or - the sensor device is articulated pivotably on the sewer inspection and/or maintenance device in order to align the part of the sensor device to be cleaned with the outlet opening of the nozzle.
A thienopyridone derivative of Formula (I): wherein: R1 represents a hydrogen atom or a halogen atom, R2 represents an indanyl or tetralinyl group, substituted or not by one or more groups selected from halogen atoms, alkyl groups, hydroxy, alkoxy groups, amino, mono- or di-alkylamino groups, carboxy groups, alkyloxycarbonyl groups, mono- or di-alkylaminocarbonyl groups, carboxamide, cyano, alkylsulfonyl and trifluoromethyl groups, R3 represents an aryl group, substituted or not by one or more atoms or groups selected from halogen atoms, alkyl groups, hydroxy, alkoxy groups, aralkyloxy groups, amino, mono- or di-alkylamino groups, carboxy groups, alkyloxycarbonyl groups, mono- or di-alkylaminocarbonyl groups, carboxamide, cyano, alkylsulfonyl and trifluoromethyl groups, or its pharmaceutically acceptable salts and/or solvates, or a pharmaceutical composition comprising the same, for use in the treatment of autosomal dominant polycystic kidney disease (ADPKD). R1 represents a hydrogen atom or a halogen atom, R2 represents an indanyl or tetralinyl group, substituted or not by one or more groups selected from halogen atoms, alkyl groups, hydroxy, alkoxy groups, amino, mono- or di-alkylamino groups, carboxy groups, alkyloxycarbonyl groups, mono- or di-alkylaminocarbonyl groups, carboxamide, cyano, alkylsulfonyl and trifluoromethyl groups, R3 represents an aryl group, substituted or not by one or more atoms or groups selected from halogen atoms, alkyl groups, hydroxy, alkoxy groups, aralkyloxy groups, amino, mono- or di-alkylamino groups, carboxy groups, alkyloxycarbonyl groups, mono- or di-alkylaminocarbonyl groups, carboxamide, cyano, alkylsulfonyl and trifluoromethyl groups, or its pharmaceutically acceptable salts and/or solvates, or a pharmaceutical composition comprising the same, for use in the treatment of autosomal dominant polycystic kidney disease (ADPKD).
A clip assembly for a rotor disk of a brake assembly, the clip assembly comprising: a clip formed of sheet metal to fit over an end of a lug of the rotor disk, the clip shaped to have a top surface that extends in a first plane from a first side and then transitions, at an opposite, second side , by a first bend into a front surface that extends in a second plane from a third side at the first bend to a fourth side and transitions by a second bend to an under-surface extending in a third plane to a fifth end , the top surface, the first bend, the front surface, the second bend and the under surface together defining a hook configuration such that, in use, the top surface fits over a top surface of the lug onto which it is mounted, the front surface fits against a front end of the lug and the under surface hooks underneath the front end of the lug; and characterized in that said clip assembly further comprising two opposing side arms extending from a first end at the top surface to a second end and transitioning over a third bend to an underside lip such that the side arms fit against sides of the lug and the underside lips hook under the lug at the sides. a clip formed of sheet metal to fit over an end of a lug of the rotor disk, the clip shaped to have a top surface that extends in a first plane from a first side and then transitions, at an opposite, second side , by a first bend into a front surface that extends in a second plane from a third side at the first bend to a fourth side and transitions by a second bend to an under-surface extending in a third plane to a fifth end , the top surface, the first bend, the front surface, the second bend and the under surface together defining a hook configuration such that, in use, the top surface fits over a top surface of the lug onto which it is mounted, the front surface fits against a front end of the lug and the under surface hooks underneath the front end of the lug; and characterized in that said clip assembly further comprising two opposing side arms extending from a first end at the top surface to a second end and transitioning over a third bend to an underside lip such that the side arms fit against sides of the lug and the underside lips hook under the lug at the sides.
A continuum arm robot section, in which the section comprises at least three segments, featuring a base segment, at least one middle segment and a tip segment, with each segment corresponding to at least one interconnecting portion between pairs of neighbouring discs that form a backbone of the section of the continuum arm robot, wherein the base segment has mg- a greater stiffness than the at least one middle segment and tip segment and the at least one middle segment has a greater stiffness than the tip segment, wherein each segment is made from a compliant and revolute joint pair and characterised in that the stiffness of the joints is determined by the surface roughness of the revolute joint.
A humanized monoclonal antibody for use in a method of treating angiogenesis and/or an angiogenesis-related disease selected from cancer, neovascular glaucoma, and age-related macular degeneration, the humanized monoclonal antibody comprising: a light chain variable region comprising the amino acid sequence as set forth in SEQ ID NO: 9; and a heavy chain variable region comprising the amino acid sequence as set forth in SEQ ID NO: 10, wherein the humanized monoclonal antibody binds to a CD34 antigen. a light chain variable region comprising the amino acid sequence as set forth in SEQ ID NO: 9; and a heavy chain variable region comprising the amino acid sequence as set forth in SEQ ID NO: 10, wherein the humanized monoclonal antibody binds to a CD34 antigen.
A method for producing ingots from metal, in particular from steel, having cross-sectional areas of at least 0.10 m 2 , of a preferably round but also square or rectangular shape, by casting metal or steel melt in a manner known per se, either directly from a casting ladle or via a tundish lined with a fireproof material, into a short water-cooled ingot mold open at the bottom and withdrawing the solidifying ingot from the same using a downwardly movable withdrawing tool , the casting process being continued with a set casting rate corresponding to the casting cross-section until the desired or maximum ingot length determined by the height of lift of the withdrawing tool is reached, and liquid metal continuing to be fed after the end of the regular casting process in such an amount that at least the diminution of the metal or steel melt occurring during solidification is made up for, characterized in that after completion of the regular casting process, during the makeup casting phase, starting in the lowest position of the ingot the metal pool is stirred by an electromagnetic stirrer which is vertically displaceable and the stirrer is displaced continuously towards the head end of the ingot as the solidification progresses.
Respirator valve, comprising: - a body provided with a disc ; - an adjustment knob attached to said body ; - a cylindrical spring positioned between said adjustment knob and the disc of the body ; and - a conical spring also placed between said adjustment knob and the disc of the body , characterized in that the body and the adjustment knob are made of a first sterilizable material and the cylindrical and conical springs are made of a second sterilizable material, and in that the respirator valve also comprises a safety ring positioned around the coupling zone between the adjustment knob and the body . - a body provided with a disc ; - an adjustment knob attached to said body ; - a cylindrical spring positioned between said adjustment knob and the disc of the body ; and - a conical spring also placed between said adjustment knob and the disc of the body , characterized in that the body and the adjustment knob are made of a first sterilizable material and the cylindrical and conical springs are made of a second sterilizable material, and in that the respirator valve also comprises a safety ring positioned around the coupling zone between the adjustment knob and the body .
Guide vane for a turbine of a turbomachine , comprising a guide vane airfoil , an inner shroud and an outer shroud , the inner shroud and the outer shroud delimiting an annular space in the radial direction with respect to a longitudinal axis of the turbomachine , in which annular space working gas is conducted during operation, and the inside of the guide vane airfoil being traversed by a guide vane airfoil channel , which extends between an inlet on the radial inside and an outlet on the radial outside, characterized in that the inlet is arranged such that a gas flowing through the guide vane airfoil channel during operation is at least partially formed by the working gas conducted in the annular space , i.e. this gas is redistributed from radially inside to radially outside into a housing region. a guide vane airfoil , an inner shroud and an outer shroud , the inner shroud and the outer shroud delimiting an annular space in the radial direction with respect to a longitudinal axis of the turbomachine , in which annular space working gas is conducted during operation, and the inside of the guide vane airfoil being traversed by a guide vane airfoil channel , which extends between an inlet on the radial inside and an outlet on the radial outside, characterized in that the inlet is arranged such that a gas flowing through the guide vane airfoil channel during operation is at least partially formed by the working gas conducted in the annular space , i.e. this gas is redistributed from radially inside to radially outside into a housing region.