mhurhangee/patent-ind-claim-en huggingface dataset:
A wheel nut and connector combination for use in a wheel rim with a plurality of studs having external threads to receive fastening nuts, the combination comprising: a plurality of hexagonal wheel nuts each with an internal thread adapted to be secured to said studs ; and a connector adapted to be attached to and connect adjacent wheel nuts ; said connector including a mechanism to prevent rotation of the wheel nuts , the connector having a base plate and a locking part , the base plate having a pair of holes which fit over two of the studs , characterised in that two of the wheel nuts and respective spacers are fastened to the studs , the locking part having two cylindrical end portions which each have internal lower rims , the locking part , being placed over the two wheel nuts such that the internal lower rims of the cylindrical end portions seat over each wheel nut and prevent movement of the wheel nuts along the shafts of the studs , and a central portion of the connector having a locking mechanism to prevent removal of the connector. a plurality of hexagonal wheel nuts each with an internal thread adapted to be secured to said studs ; and a connector adapted to be attached to and connect adjacent wheel nuts ; said connector including a mechanism to prevent rotation of the wheel nuts , the connector having a base plate and a locking part , the base plate having a pair of holes which fit over two of the studs , characterised in that two of the wheel nuts and respective spacers are fastened to the studs , the locking part having two cylindrical end portions which each have internal lower rims , the locking part , being placed over the two wheel nuts such that the internal lower rims of the cylindrical end portions seat over each wheel nut and prevent movement of the wheel nuts along the shafts of the studs , and a central portion of the connector having a locking mechanism to prevent removal of the connector.
An anti-GD3 specific chimeric antigen receptor (CAR) having one of the polypeptide structure selected from V2 and V3 as depicted in Figure 4, said structure comprising a signal peptide, an extra cellular ligand binding-domain comprising VH and VL from a monoclonal anti-GD3 antibody, a CD8α hinge having at least 90% sequence identity with SEQ ID NO. 4 or a IgG1 hinge having at least 90% sequence identity with SEQ ID NO: 5, a CD8α transmembrane domain having at least 90 % sequence identity with SEQ ID NO. 6, and a cytoplasmic domain including a CD3 zeta signaling domain having at least 90% sequence identity with SEQ ID NO. 8 and a co-stimulatory domain from 4-1BB having at least 90% sequence identity with SEQ ID NO. 9; wherein said VH comprises the CDR sequences of SEQ ID NO.36 (CDR1), SEQ ID NO.37 (CDR2) and SEQ ID NO.38 (CDR3), and said VL comprises the CDR sequences of SEQ ID NO.39 (CDR1), SEQ ID NO.40 (CDR2) and SEQ ID NO.41 (CDR3), wherein said CAR optionally lacks the signal peptide.
A system comprising: a plurality of summarization engines , each summarization engine to receive video content and provide a summary of the video content , thereby providing a plurality of summaries of the video content ; a plurality of meta-algorithmic patterns , each meta-algorithmic pattern to be applied to at least two of the summaries to provide a meta-summary of the video content using the at least two summaries, thereby providing a plurality of meta-summaries of the video content ; and an evaluator to create a new class by clustering videos that are similar and then manually or automatically tagging that cluster as a new class, to evaluate the plurality of summaries and the plurality of meta-summaries, and to select a class of a plurality of classes or the new class based on similarity measures. a plurality of summarization engines , each summarization engine to receive video content and provide a summary of the video content , thereby providing a plurality of summaries of the video content ; a plurality of meta-algorithmic patterns , each meta-algorithmic pattern to be applied to at least two of the summaries to provide a meta-summary of the video content using the at least two summaries, thereby providing a plurality of meta-summaries of the video content ; and an evaluator to create a new class by clustering videos that are similar and then manually or automatically tagging that cluster as a new class, to evaluate the plurality of summaries and the plurality of meta-summaries, and to select a class of a plurality of classes or the new class based on similarity measures.
Sensor comprising - a deformation body having a diaphragm for deformation when subjected to pressure by a medium, - a strain element applied to the diaphragm and secured on the diaphragm , wherein - the strain element is based on SOI technology and has a silicon substrate , a silicon dioxide layer and a plurality of piezoresistive resistors , characterized in that the piezoresistive resistors each comprise a spatially freed Si nanowire, wherein spatially freed means that the Si nanowires are undercut rather than supported over part of their length. - a deformation body having a diaphragm for deformation when subjected to pressure by a medium, - a strain element applied to the diaphragm and secured on the diaphragm , wherein - the strain element is based on SOI technology and has a silicon substrate , a silicon dioxide layer and a plurality of piezoresistive resistors ,
A speaker comprising: a frame ; a diaphragm that the frame supports so as to enable the diaphragm to vibrate; a coil that drives the diaphragm to vibrate; and a magnetic circuit that is positioned rearward relative to the diaphragm and applies a magnetic field to the coil, wherein the frame has a magnetic circuit holder in which the magnetic circuit is held, the magnetic circuit has a restriction surface that faces frontward; a pressing portion with a ring-like body provided with pressing arms that protrude from the ring-like body towards the center axis of the ring-like body, the arms being elastically deformable and disposed so as to be in contact with the restriction surface, and contact portions between respective pressing arms and the restriction surface are disposed with spacing therebetween in the circumferential direction; wherein each pressing arm has a substantially triangular shape of which the width gradually becomes smaller towards a tip portion of the pressing arm protruding towards the center of the ring-like body . a frame ; a diaphragm that the frame supports so as to enable the diaphragm to vibrate; a coil that drives the diaphragm to vibrate; and a magnetic circuit that is positioned rearward relative to the diaphragm and applies a magnetic field to the coil, wherein the frame has a magnetic circuit holder in which the magnetic circuit is held, the magnetic circuit has a restriction surface that faces frontward; a pressing portion with a ring-like body provided with pressing arms that protrude from the ring-like body towards the center axis of the ring-like body, the arms being elastically deformable and disposed so as to be in contact with the restriction surface, and contact portions between respective pressing arms and the restriction surface are disposed with spacing therebetween in the circumferential direction; wherein each pressing arm has a substantially triangular shape of which the width gradually becomes smaller towards a tip portion of the pressing arm protruding towards the center of the ring-like body .
A kit for determining methylation status of at least one CpG dinucleotide and a genotype of at least one single-nucleotide polymorphism (SNP), the kit comprising at least one first nucleic acid primer at least 8 nucleotides in length that is complementary to a bisulfite-converted nucleic acid sequence comprising a CpG dinucleotide cg26910465 from the Adenosine deaminase-like protein (ADAL) gene, wherein the at least one first nucleic acid primer detects an unmethylated CpG dinucleotide, and at least one second nucleic acid primer at least 8 nucleotides in length that is complementary to a DNA sequence of a first SNP rs 10275666 or a second SNP in linkage disequilibrium with the first SNP, wherein the linkage disequilibrium has a value of R>0.3. at least one first nucleic acid primer at least 8 nucleotides in length that is complementary to a bisulfite-converted nucleic acid sequence comprising a CpG dinucleotide cg26910465 from the Adenosine deaminase-like protein (ADAL) gene, wherein the at least one first nucleic acid primer detects an unmethylated CpG dinucleotide, and at least one second nucleic acid primer at least 8 nucleotides in length that is complementary to a DNA sequence of a first SNP rs 10275666 or a second SNP in linkage disequilibrium with the first SNP, wherein the linkage disequilibrium has a value of R>0.3.
A medical apparatus for a patient comprising: an external system configured to transmit one or more transmission signals, each transmission signal comprising at least power or data, and the external system comprising an external device; and an implantable system configured to receive the one or more transmission signals from the external system; wherein the implantable system comprises an implantable device comprising an antenna , a power management assembly , an energy storage assembly , a pulse generator , and at least one functional element , wherein the power management assembly is configured to store energy in the energy storage assembly and provide energy to the implantable system, wherein the energy storage assembly is configured to provide power for the pulse generator , and the pulse generator is configured to deliver stimulation energy to the at least one functional element, wherein the at least one functional element comprises at least one energy delivery element , and wherein the power management assembly comprises a rectifier to produce an output voltage, a boost converter configured to boost the rectifier's output voltage to charge the energy storage assembly, and a regulator, the power management assembly being configured to control the current at which the boost converter charges the energy storage assembly to prevent the output voltage from falling below a threshold in order to optimize efficiency of the boost converter. an external system configured to transmit one or more transmission signals, each transmission signal comprising at least power or data, and the external system comprising an external device; and an implantable system configured to receive the one or more transmission signals from the external system; wherein the implantable system comprises an implantable device comprising an antenna , a power management assembly , an energy storage assembly , a pulse generator , and at least one functional element , wherein the power management assembly is configured to store energy in the energy storage assembly and provide energy to the implantable system, wherein the energy storage assembly is configured to provide power for the pulse generator , and the pulse generator is configured to deliver stimulation energy to the at least one functional element, wherein the at least one functional element comprises at least one energy delivery element , and wherein the power management assembly comprises a rectifier to produce an output voltage, a boost converter configured to boost the rectifier's output voltage to charge the energy storage assembly, and a regulator, the power management assembly being configured to control the current at which the boost converter charges the energy storage assembly to prevent the output voltage from falling below a threshold in order to optimize efficiency of the boost converter.
A resource configuration method, comprising: receiving , by a first node, before uplink or downlink scheduling, first configuration information sent by a second node, wherein the second node is a parent node of the first node; and determining , by the first node based on the first configuration information, a first resource for communication between the first node and a child node served by the first node, wherein the first resource is at least one demodulation reference signal, DMRS, port occupied by a first access link, the at least one DMRS port is a part of ports in a DMRS port set corresponding to a first slot, and the first access link is a link between the first node and the child node served by the first node, such that when uplink or downlink scheduling for the first slot is performed, the first node selects an available DMRS port from the first resource for transmission on the first access link, wherein the first slot is any one of slots that are used for spatial multiplexing and that are configured by the second node for the backhaul link between the first node and the second node, and the slot used for spatial multiplexing is a slot in which data sending or receiving can be simultaneously performed on a backhaul link and an access link of a same node that share a same frequency band. receiving , by a first node, before uplink or downlink scheduling, first configuration information sent by a second node, wherein the second node is a parent node of the first node; and determining , by the first node based on the first configuration information, a first resource for communication between the first node and a child node served by the first node, wherein the first resource is at least one demodulation reference signal, DMRS, port occupied by a first access link, the at least one DMRS port is a part of ports in a DMRS port set corresponding to a first slot, and the first access link is a link between the first node and the child node served by the first node, such that when uplink or downlink scheduling for the first slot is performed, the first node selects an available DMRS port from the first resource for transmission on the first access link, wherein the first slot is any one of slots that are used for spatial multiplexing and that are configured by the second node for the backhaul link between the first node and the second node, and the slot used for spatial multiplexing is a slot in which data sending or receiving can be simultaneously performed on a backhaul link and an access link of a same node that share a same frequency band.
A crucible for heating a material to be vaporized or sublimed, comprising at least one concave recess , the concave recess is applicable to accommodating a material to be vaporized or sublimed, and the concave recess is formed on a first surface of the crucible ; and a bottom recess and a side recess (13a-13d), the bottom recess is formed on a second surface of the crucible , the second surface is opposite to the first surface , and the side recess (13a-13d) is formed in a side wall (141-144) of the crucible , the side wall (141-144) extends from the first surface to the second surface , wherein the side recess (13a-13d) has an opening near the second surface of the crucible . at least one concave recess , the concave recess is applicable to accommodating a material to be vaporized or sublimed, and the concave recess is formed on a first surface of the crucible ; and a bottom recess and a side recess (13a-13d), the bottom recess is formed on a second surface of the crucible , the second surface is opposite to the first surface , and the side recess (13a-13d) is formed in a side wall (141-144) of the crucible , the side wall (141-144) extends from the first surface to the second surface , wherein the side recess (13a-13d) has an opening near the second surface of the crucible .
A cyclic peptide comprising an amino acid sequence ( I ), wherein said amino acid sequence (I) comprises, preferably consists of, the amino acid sequence: wherein X1, X2, X3, X5, X6, X7, X9, X10, X11, X22, X23, X24, X26, X27, X28 and X29 are independently of each other an amino acid; C4, C8, C21 and C25 are independently of each other cysteine; P12 is proline; I13 is isoleucine; T14 is threonine; N15 is asparagine; D16 is aspartic acid; Q17 is glutamine; K18 and K19 are independently of each other lysine; L20 is leucine; and X30 is an amino acid or a deletion, wherein said cysteines C4 and C25 form a first disulfide bond and said cysteines C8 and C21 form a second disulfide bond. wherein X1, X2, X3, X5, X6, X7, X9, X10, X11, X22, X23, X24, X26, X27, X28 and X29 are independently of each other an amino acid; C4, C8, C21 and C25 are independently of each other cysteine; P12 is proline; I13 is isoleucine; T14 is threonine; N15 is asparagine; D16 is aspartic acid; Q17 is glutamine; K18 and K19 are independently of each other lysine; L20 is leucine; and X30 is an amino acid or a deletion, wherein said cysteines C4 and C25 form a first disulfide bond and said cysteines C8 and C21 form a second disulfide bond.
A data logger for logging values of a physical environment parameter as a function of time, which data logger comprises - a sampling subsystem for acquiring a sequence of sample values of the physical environment parameter at sampling moments which are separated by sample intervals, - an encoding subsystem arranged for converting the sequence of sample values in data records comprising a representative values representing groups of one sample value or a number of successive sample values with variations which meet a stability criterion, whereby the data records comprises information representative of the lengths of the groups - a memory subsystem for storing a sequence of the defined data records into a memory, wherein the data logger is arranged to determine in which range of a plurality of ranges a sample of the environment parameter is located, and to use a stability criterion for the encoding which depends on the determined range, and characterized in that a length of the sampling interval is settable to a first length and to a second length which is different than the first length, whereby the sampling subsystem is arranged to set the length of the sample interval time to the second length in response to a detection that a variation speed dependent stability criterion is not met, which variation dependent stability criterion indicates that the speed with the physical environment parameter changes over time exceeds a predefined level. - a sampling subsystem for acquiring a sequence of sample values of the physical environment parameter at sampling moments which are separated by sample intervals, - an encoding subsystem arranged for converting the sequence of sample values in data records comprising a representative values representing groups of one sample value or a number of successive sample values with variations which meet a stability criterion, whereby the data records comprises information representative of the lengths of the groups - a memory subsystem for storing a sequence of the defined data records into a memory,
A staple cartridge, comprising: a cartridge body comprising a deck and staple cavities; staples at least partially positioned within said staple cavities; a layer attached to said deck, wherein said layer at least partially extends over said staple cavities; a retention pin engaged with said layer to secure said layer to said cartridge body; and a firing member movable through said cartridge body to eject said staples from said staple cavities during a firing stroke of said firing member, characterised in that said firing member is configured to disengage said retention pin from said layer during said firing stroke by lowering the retention pin relative to the deck to release said layer from said cartridge body. a cartridge body comprising a deck and staple cavities; staples at least partially positioned within said staple cavities; a layer attached to said deck, wherein said layer at least partially extends over said staple cavities; a retention pin engaged with said layer to secure said layer to said cartridge body; and a firing member movable through said cartridge body to eject said staples from said staple cavities during a firing stroke of said firing member, characterised in that said firing member is configured to disengage said retention pin from said layer during said firing stroke by lowering the retention pin relative to the deck to release said layer from said cartridge body.
Use of a low conductivity aqueous solution in a wash step of a protein A chromatography for reducing the content of a host cell protein wherein the protein A chromatography is used to purify a human IgG4 or IgG1 isotype antibody, wherein the low conductivity aqueous solution has a conductivity value of about 0.5 mS/cm or less, wherein the host cell protein is phospholipase B-like 2 (PLBL2) or Clusterin.
A method for producing a lithium metal phosphate, characterized in that the method comprises: initiating and allowing to proceed, in the presence of a polar solvent, a conversion reaction of a lithium ion (Li + ) source, a divalent transition metal ion (M 2+ ) source, and a phosphate ion (PO 4 3- ) source into a lithium metal phosphate at 150°C or higher, by bringing a solution A containing one of a lithium ion, a divalent transition metal ion and a phosphate ion into contact with a solution B containing the others of these ions at a temperature of 150°C or higher so as to obtain a mixture of the solution A and the solution B, the mixture having a pH of 4 or higher.
A tissue removal system , comprising: an electrosurgical generator including an active electrode port and a return electrode port ; an active electrode device configured to connect to the active electrode port ; and a tissue guard including a body with a passageway configured to permit passage of instrumentation and tissue there-through, wherein the tissue guard comprises an electrically-insulative proximal portion, an at least partially electrically-conductive distal portion, and a cable configured to connect the at least partially electrically-conductive distal portion to the return electrode port , wherein an inwardly-facing surface of the tissue guard is at least partially electrically-conductive to provide a first electrically-conductive portion and a second electrically-conductive portion , said first and second electrically-conductive portions being configured to connect to the return electrode port . an electrosurgical generator including an active electrode port and a return electrode port ; an active electrode device configured to connect to the active electrode port ; and a tissue guard including a body with a passageway configured to permit passage of instrumentation and tissue there-through, wherein the tissue guard comprises an electrically-insulative proximal portion, an at least partially electrically-conductive distal portion, and a cable configured to connect the at least partially electrically-conductive distal portion to the return electrode port , wherein an inwardly-facing surface of the tissue guard is at least partially electrically-conductive to provide a first electrically-conductive portion and a second electrically-conductive portion , said first and second electrically-conductive portions being configured to connect to the return electrode port .