mhurhangee/patent-ind-claim-en huggingface dataset:
A search method for cascading failures in a hybrid AC/DC power system, cascading failures including a first-level failure and a next-level failure caused by the cascade of failures the method being characterized by comprising: step 1: determining an initial failure and forming a failure set of the first-stage failures; setting a DC blocking or the number of failure levels reaching a threshold as a search stop condition; step 2: judging whether cascading failures in the current stage failure set can trigger a DC blocking; if the cascading failure causes a DC blocking, the DC blocking failure is stored in a next stage of the cascading failure; otherwise, based on a pruning search method and an outage risk value, cascading failures are searched on an AC side and the failure set of the next stage is determined; step 3: if the search stop condition is satisfied, stop the search; otherwise, the number of failure stages is increased by one and return to Step 2 to continue the search step 4: providing, after iterations of step 2 and 3, cascading failure chains having a failure chain probability that can cause DC blocking in the hybrid AC/DC power system wherein, in the Step 1, AC lines near a vicinity of a DC terminal location in the hybrid AC/DC power system are selected as the initial failures in the cascading failure search, and the initial failures are simulated in time-domain to check whether it will trigger a DC blocking. step 1: determining an initial failure and forming a failure set of the first-stage failures; setting a DC blocking or the number of failure levels reaching a threshold as a search stop condition; step 2: judging whether cascading failures in the current stage failure set can trigger a DC blocking; if the cascading failure causes a DC blocking, the DC blocking failure is stored in a next stage of the cascading failure; otherwise, based on a pruning search method and an outage risk value, cascading failures are searched on an AC side and the failure set of the next stage is determined; step 3: if the search stop condition is satisfied, stop the search; otherwise, the number of failure stages is increased by one and return to Step 2 to continue the search step 4: providing, after iterations of step 2 and 3, cascading failure chains having a failure chain probability that can cause DC blocking in the hybrid AC/DC power system wherein, in the Step 1, AC lines near a vicinity of a DC terminal location in the hybrid AC/DC power system are selected as the initial failures in the cascading failure search, and the initial failures are simulated in time-domain to check whether it will trigger a DC blocking.
Method for manufacturing a fiber-reinforced composite material the method comprising: molding a stack obtained by laminating a plurality of sheet-shaped prepregs (X) including a plurality of consecutively arranged reinforcing fibers impregnated with a matrix resin composition such that fiber directions are different from each other into a three-dimensional shape by using a molding die equipped with a pair of , wherein a pair of the dies are brought close to each other in a state in which a stretchable resin or rubber sheet is disposed between one die of a pair of the dies constituting the molding die and the stack while being tensioned in a specific direction and the stack is molded by a pair of the dies while extending the stretchable sheet. molding a stack obtained by laminating a plurality of sheet-shaped prepregs (X) including a plurality of consecutively arranged reinforcing fibers impregnated with a matrix resin composition such that fiber directions are different from each other into a three-dimensional shape by using a molding die equipped with a pair of , wherein a pair of the dies are brought close to each other in a state in which a stretchable resin or rubber sheet is disposed between one die of a pair of the dies constituting the molding die and the stack while being tensioned in a specific direction and the stack is molded by a pair of the dies while extending the stretchable sheet.
A vibration damper and/or absorber including a first member having a bearing region and a friction contact region , and a second member including a body which is mounted on the bearing region for axial displacement with respect to the first member along an axis, the second member including a resilient member which extends axially from the body and which has a friction surface which resiliently engages the contact region of the first member , whereby relative linear displacement between the first and second members is opposed by frictional contact between the friction surface and the contact region , and characterised in that the resilient member constitutes a first resilient finger extending axially from the body in a first direction and in which the contact region constitutes a first contact region situated axially on one side of the bearing region , the body being provided with at least one second resilient member aligned with the or each respective first resilient member and extending axially from the body in a second direction opposite to the first direction and contacting a second contact region of the first member , situated axially on the other side of the bearing region .
A compound for use in the treatment or prevention of a coronavirus infection in a subject in need thereof, wherein the compound is probenecid or a metabolite or analog thereof or a pharmaceutically acceptable salt thereof, wherein the metabolite or analog thereof is an acyl glucuronide of probenecid, a β-ether glucuronide of probenecid, dl-p- ( N -propyl- N -2-hydroxypropylsulfamoyl)benzoic acid, p- ( N -Propyl- N -3-hydroxypropylsulfamoyl)benzoic acid, p- ( N -propyl- N -3-propionitrilosulfamoyl)benzoic acid, p- ( N -propyl- N -2-carboxyethylsulfamoyl)benzoic acid, p- ( N -propylsulfamoyl)benzoic acid, p- ( N,N -pentamethylenesulfamoyl)benzoic acid (piperidyl analog), p- ( N -propyl- N -2-propenylsulfamoyl)benzoic acid, p- ( N -propyl- N -2-oxopropylsulfamoyl)benzoic acid, p-sulfamoylbenzoic acid, p- ( N -methylsulfamoyl)benzoic acid, p- ( N -ethylsulfamoyl)benzoic acid, p- ( N- hexylsulfamoyl)benzoic acid, p- ( N- cyclohexylsulfamoyl)benzoic acid, p- ( N- dimethylsulfamoyl)benzoic acid, p- ( N -methyl, N -ethylsulfamoyl)benzoic acid, p- ( N,N -diethylsulfamoyl)benzoic acid, p-(N-ethyl,N-propylsulfamoyl)benzoic acid, p-(N,N-diisopropylsulfamoyl)benzoic acid, p- ( N,N -dibutylsulfamoyl)benzoic acid, o -hydroxy- p- ( N -dipropylsulfamoyl)benzoic acid, o -methoxy- p- ( N -dipropylsulfamoyl)benzoic acid, o -nitro- p- ( N,N -dipropylsulfamoyl)benzoic acid, m -nitro- p- ( N,N -dipropylsulfamoyl)benzoic acid or m -methyl- p- ( N,N -dipropylsulfamoyl)benzoic acid. an acyl glucuronide of probenecid, a β-ether glucuronide of probenecid, dl-p- ( N -propyl- N -2-hydroxypropylsulfamoyl)benzoic acid, p- ( N -Propyl- N -3-hydroxypropylsulfamoyl)benzoic acid, p- ( N -propyl- N -3-propionitrilosulfamoyl)benzoic acid, p- ( N -propyl- N -2-carboxyethylsulfamoyl)benzoic acid, p- ( N -propylsulfamoyl)benzoic acid, p- ( N,N -pentamethylenesulfamoyl)benzoic acid (piperidyl analog), p- ( N -propyl- N -2-propenylsulfamoyl)benzoic acid, p- ( N -propyl- N -2-oxopropylsulfamoyl)benzoic acid, p-sulfamoylbenzoic acid, p- ( N -methylsulfamoyl)benzoic acid, p- ( N -ethylsulfamoyl)benzoic acid, p- ( N- hexylsulfamoyl)benzoic acid, p- ( N- cyclohexylsulfamoyl)benzoic acid, p- ( N- dimethylsulfamoyl)benzoic acid, p- ( N -methyl, N -ethylsulfamoyl)benzoic acid, p- ( N,N -diethylsulfamoyl)benzoic acid, p-(N-ethyl,N-propylsulfamoyl)benzoic acid, p-(N,N-diisopropylsulfamoyl)benzoic acid, p- ( N,N -dibutylsulfamoyl)benzoic acid, o -hydroxy- p- ( N -dipropylsulfamoyl)benzoic acid, o -methoxy- p- ( N -dipropylsulfamoyl)benzoic acid, o -nitro- p- ( N,N -dipropylsulfamoyl)benzoic acid, m -nitro- p- ( N,N -dipropylsulfamoyl)benzoic acid or m -methyl- p- ( N,N -dipropylsulfamoyl)benzoic acid.
A process for the preparation of 4-cyanobenzoyl chlorides of formula I, wherein R is halogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, or C 1 -C 4 -haloalkoxy; n is 0, 1 or 2; the process comprising reacting a compound of formula II, wherein the variable R is as defined above for compounds of formula I, with a chlorinating agent. R is halogen, C 1 -C 4 -alkyl, C 1 -C 4 -haloalkyl, C 1 -C 4 -alkoxy, or C 1 -C 4 -haloalkoxy; n is 0, 1 or 2;
An integrated spectral sensing device, comprising: a first substrate comprising an attenuated total internal reflection ATR, element , a microfluidic channel , and a channel interface corresponding to a boundary between the ATR element and the microfluidic channel formed therein, the ATR element configured to receive input light and to produce output light based on total internal reflection of the input light at the channel interface , the output light being attenuated by an evanescent wave produced by a sample contained within the microfluidic channel based on the total internal reflection of the input light; a spectrometer configured to produce an interference beam , the interference beam corresponding to the input light or being produced based on the output light; and a detector configured to detect a spectrum of the interference beam or the output light ; characterized in that the channel interface is formed at sidewalls of the ATR element . a first substrate comprising an attenuated total internal reflection ATR, element , a microfluidic channel , and a channel interface corresponding to a boundary between the ATR element and the microfluidic channel formed therein, the ATR element configured to receive input light and to produce output light based on total internal reflection of the input light at the channel interface , the output light being attenuated by an evanescent wave produced by a sample contained within the microfluidic channel based on the total internal reflection of the input light; a spectrometer configured to produce an interference beam , the interference beam corresponding to the input light or being produced based on the output light; and a detector configured to detect a spectrum of the interference beam or the output light ;
A MTMR2-S polypeptide, or a nucleic acid sequence producing or encoding said MTMR2-S polypeptide, for use in the treatment of X-linked centronuclear myopathy (XLCNM).
A stack-folding type of electrode assembly comprising: a plurality of unit cells including a lithium metal negative electrode, a positive electrode, and a separation film provided between the lithium metal negative electrode and the positive electrode; a folding separation film continuously provided among unit cells neighboring each other; and an insulation tape respectively attached to an upper side and a lower side of the folding separation film, wherein the insulation tape is exposed to an outside at the upper side and the lower side that are opened portions of the stack-folding type of electrode assembly. a plurality of unit cells including a lithium metal negative electrode, a positive electrode, and a separation film provided between the lithium metal negative electrode and the positive electrode; a folding separation film continuously provided among unit cells neighboring each other; and an insulation tape respectively attached to an upper side and a lower side of the folding separation film, wherein the insulation tape is exposed to an outside at the upper side and the lower side that are opened portions of the stack-folding type of electrode assembly.
A connection device, comprising: a waterproof cover , comprising a water blocking portion , a sealing portion , and an inserting portion ; and a connector , comprising a head end and a tail end arranged opposite to the head end , the head end being provided with an insertion port configured to be inserted with an external plug and the tail end being configured to be connected to a conductive wire , wherein the water blocking portion is configured to surround a periphery of the connector ; the sealing portion is integrally formed at an end of the water blocking portion and configured to sleeve on the tail end of the connector to seal the tail end of the connector ; the inserting portion is integrally formed at an end of the water blocking portion opposite to the sealing portion , and includes an inner sidewall fitting to the periphery of the head end of the connector and an outer sidewall arranged opposite to the inner sidewall ; the connector is configured to be fit into the water blocking portion of the waterproof cover , wherein the tail end of the connector passes through the sealing portion of the waterproof cover , characterized in that the waterproof cover is made up of a hard layer and a flexible layer laminated on each of the inner side and outer side of the hard layer ; an inner sidewall of the sealing portion is provided with a sealing waterproof rib along a circumferential direction, and the sealing waterproofing rib is integrally formed with the flexible layer and is configured to be abutted on an outer sidewall of the connector . a waterproof cover , comprising a water blocking portion , a sealing portion , and an inserting portion ; and a connector , comprising a head end and a tail end arranged opposite to the head end , the head end being provided with an insertion port configured to be inserted with an external plug and the tail end being configured to be connected to a conductive wire , wherein the water blocking portion is configured to surround a periphery of the connector ; the sealing portion is integrally formed at an end of the water blocking portion and configured to sleeve on the tail end of the connector to seal the tail end of the connector ; the inserting portion is integrally formed at an end of the water blocking portion opposite to the sealing portion , and includes an inner sidewall fitting to the periphery of the head end of the connector and an outer sidewall arranged opposite to the inner sidewall ; the connector is configured to be fit into the water blocking portion of the waterproof cover , wherein the tail end of the connector passes through the sealing portion of the waterproof cover , characterized in that the waterproof cover is made up of a hard layer and a flexible layer laminated on each of the inner side and outer side of the hard layer ; an inner sidewall of the sealing portion is provided with a sealing waterproof rib along a circumferential direction, and the sealing waterproofing rib is integrally formed with the flexible layer and is configured to be abutted on an outer sidewall of the connector .
A bioprinting system for printing tissue into a tissue enclosure comprising: a multi-dimensional printer; a delivery device operably coupled to the multi-dimensional printer, the delivery device comprising a tool having a tip for printing the tissue; a motion controller commanding the delivery device to print the tissue; and a delivery device locating subsystem returning the tip to a selected position within the printed tissue, wherein the delivery device locating subsystem comprises: a mounting plate including kinematic positioning features; a tissue enclosure being a repository for the printed tissue, the tissue enclosure including kinematic mounting features matably couplable with the kinematic positioning features, the mounting features and the positioning features ensuring consistent positioning of the tissue enclosure between mounting and remounting of the tissue enclosure; and at least one sensor enabling determining the position of the delivery device within the tissue enclosure. a multi-dimensional printer; a delivery device operably coupled to the multi-dimensional printer, the delivery device comprising a tool having a tip for printing the tissue; a motion controller commanding the delivery device to print the tissue; and a delivery device locating subsystem returning the tip to a selected position within the printed tissue, wherein the delivery device locating subsystem comprises: a mounting plate including kinematic positioning features; a tissue enclosure being a repository for the printed tissue, the tissue enclosure including kinematic mounting features matably couplable with the kinematic positioning features, the mounting features and the positioning features ensuring consistent positioning of the tissue enclosure between mounting and remounting of the tissue enclosure; and at least one sensor enabling determining the position of the delivery device within the tissue enclosure. a mounting plate including kinematic positioning features; a tissue enclosure being a repository for the printed tissue, the tissue enclosure including kinematic mounting features matably couplable with the kinematic positioning features, the mounting features and the positioning features ensuring consistent positioning of the tissue enclosure between mounting and remounting of the tissue enclosure; and at least one sensor enabling determining the position of the delivery device within the tissue enclosure.
Measuring tube for a measuring device, particularly for a flowmeter, wherein said measuring tube, which is particularly hollow cylindrical at least in sections, comprises: - a tubular meter body , particularly metal and/or at least partially hollow cylindrical, wherein said meter body has a wall and an interior channel surrounding said wall, particularly a cylindrical interior channel, wherein said channel is designed to conduct a fluid medium (FL1); - as well as a sensor holder which is arranged on an outer lateral surface - situated opposite the interior channel, particularly at least partially curved - of the wall of the meter body , wherein said channel is connected to said wall via a substance-to-substance connection, said sensor holder being particularly metal and/or designed as a connection nozzle, wherein said sensor holder is designed to be connected mechanically, particularly in a detachable manner, to at least one sensor component, particularly a component of a sensor serving to measure at least a measured variable of a medium located in the interior channel; - wherein the meter body is formed by means of a cast, pressed or welded pipe and/or is made by means of a forming process; - and wherein the sensor holder is made at least partially by means of an additive manufacturing technology, particularly production in free space and/or selective laser melting, directly on the lateral surface of the wall of the meter body. - a tubular meter body , particularly metal and/or at least partially hollow cylindrical, wherein said meter body has a wall and an interior channel surrounding said wall, particularly a cylindrical interior channel, wherein said channel is designed to conduct a fluid medium (FL1); - as well as a sensor holder which is arranged on an outer lateral surface - situated opposite the interior channel, particularly at least partially curved - of the wall of the meter body , wherein said channel is connected to said wall via a substance-to-substance connection, said sensor holder being particularly metal and/or designed as a connection nozzle, wherein said sensor holder is designed to be connected mechanically, particularly in a detachable manner, to at least one sensor component, particularly a component of a sensor serving to measure at least a measured variable of a medium located in the interior channel; - wherein the meter body is formed by means of a cast, pressed or welded pipe and/or is made by means of a forming process; - and wherein the sensor holder is made at least partially by means of an additive manufacturing technology, particularly production in free space and/or selective laser melting, directly on the lateral surface of the wall of the meter body.
A gas circuit breaker comprising: a rod-shaped fixed arc contact ; a cylindrical movable arc contact to contact or be separated from the fixed arc contact, the movable arc contact having a plurality of contact pieces provided on an end of the movable arc contact facing the fixed arc contact, the contact pieces being separated from one another by a plurality of slits arranged in a circumferential direction of the movable arc contact and extending in an axial direction of the movable arc contact, each of the contact pieces having a proximal part and a distal end part larger in radial thickness than the proximal part; and a puffer chamber (20;21)storing an arc-extinguishing gas to be blown to an arc generated between the fixed arc contact and the movable arc contact, characterized in that : an insulator is received within a receiving hole formed in the distal end parts of the plurality of contact pieces , the receiving hole being open on a side away from the fixed arc contact; a portion of an end surface of the insulator on a side of the insulator facing the fixed arc contact faces the fixed arc contact via openings at ends of the slits on the end of the movable arc contact facing the fixed arc contact; and the insulator is made of an ablation material to be vaporized by heat of the arc. a rod-shaped fixed arc contact ; a cylindrical movable arc contact to contact or be separated from the fixed arc contact, the movable arc contact having a plurality of contact pieces provided on an end of the movable arc contact facing the fixed arc contact, the contact pieces being separated from one another by a plurality of slits arranged in a circumferential direction of the movable arc contact and extending in an axial direction of the movable arc contact, each of the contact pieces having a proximal part and a distal end part larger in radial thickness than the proximal part; and a puffer chamber (20;21)storing an arc-extinguishing gas to be blown to an arc generated between the fixed arc contact and the movable arc contact, characterized in that : an insulator is received within a receiving hole formed in the distal end parts of the plurality of contact pieces , the receiving hole being open on a side away from the fixed arc contact; a portion of an end surface of the insulator on a side of the insulator facing the fixed arc contact faces the fixed arc contact via openings at ends of the slits on the end of the movable arc contact facing the fixed arc contact; and the insulator is made of an ablation material to be vaporized by heat of the arc. an insulator is received within a receiving hole formed in the distal end parts of the plurality of contact pieces , the receiving hole being open on a side away from the fixed arc contact; a portion of an end surface of the insulator on a side of the insulator facing the fixed arc contact faces the fixed arc contact via openings at ends of the slits on the end of the movable arc contact facing the fixed arc contact; and the insulator is made of an ablation material to be vaporized by heat of the arc.
A CDK9 inhibitor, selected from the group consisting of PHA 767491, DRB, SNS-032, flavopiridol and shRNAs against CDK9, for use in treating cancer in a subject overexpressing MYC wherein the cancer is hepatocellular carcinoma.