mhurhangee/patent-ind-claim-en huggingface dataset:
A pharmaceutical composition for use in a method of reducing macrophage infiltration, scar formation, or stenosis at a site of graft implantation in a subject comprising: a) one or more inhibitors of lysosomal trafficking regulator (LYST) in an amount effective to reduce macrophage infiltration, natural killer cell activation, and/or platelet activation in the subject, and b) a physiologically acceptable carrier, wherein the composition is administered to the subject prior to surgery, at the time of surgery, and/or within days after surgery, and wherein the amount of one or more inhibitors of LYST is between 0.1 and 1000 mg/kg body weight of a human and does not prevent wound healing. a) one or more inhibitors of lysosomal trafficking regulator (LYST) in an amount effective to reduce macrophage infiltration, natural killer cell activation, and/or platelet activation in the subject, and b) a physiologically acceptable carrier,
A method of processing a video signal based on an inter prediction, the method comprising: constructing a first merge candidate list of a current block using a plurality of merge candidates including spatial merge candidates and a temporal merge candidate of the current block, the spatial merge candidates preceding the temporal merge candidate in the first merge candidate list; constructing a second merge candidate list by adding history-based merge candidates indicating motion information of blocks coded prior to the current block to the first merge candidate list; obtaining a merge index indicating a merge candidate applied to the current block within the second merge candidate list; and generating a prediction block of the current block using motion information of a merge candidate indicated by the merge index, wherein the history-based merge candidate is added to the first merge candidate list if the history-based merge candidate has motion information not overlapping motion information of a pre-defined merge candidate among merge candidates included in the first merge candidate list, wherein the history-based merge candidates are derived from a history-based buffer in an addition sequence different from an index order of the history-based buffer, the index order indicating an order in which the history-based merge candidates are added to the history-based buffer, and wherein information on the addition sequence is signaled through a higher level syntax. constructing a first merge candidate list of a current block using a plurality of merge candidates including spatial merge candidates and a temporal merge candidate of the current block, the spatial merge candidates preceding the temporal merge candidate in the first merge candidate list; constructing a second merge candidate list by adding history-based merge candidates indicating motion information of blocks coded prior to the current block to the first merge candidate list; obtaining a merge index indicating a merge candidate applied to the current block within the second merge candidate list; and generating a prediction block of the current block using motion information of a merge candidate indicated by the merge index, wherein the history-based merge candidate is added to the first merge candidate list if the history-based merge candidate has motion information not overlapping motion information of a pre-defined merge candidate among merge candidates included in the first merge candidate list, wherein the history-based merge candidates are derived from a history-based buffer in an addition sequence different from an index order of the history-based buffer, the index order indicating an order in which the history-based merge candidates are added to the history-based buffer, and wherein information on the addition sequence is signaled through a higher level syntax.
A device for the esophageal compression of a patient's aorta, comprising: an elongate tube ; an actuator handle at a proximal end of said elongate tube ; and a head assembly at a distal end of said elongate tube , said head assembly further comprising a pair of clamp blades that are mounted to said elongate tube for slidable movement along a first axis that is perpendicular to a second, longitudinal axis of said elongate tube , and that are mounted to said elongate tube for pivotable movement about said first axis; wherein said actuator handle engages said head assembly to cause said head assembly to move through at least one of three distinct degrees of freedom of movement to apply pressure to a patient's tissue. an elongate tube ; an actuator handle at a proximal end of said elongate tube ; and a head assembly at a distal end of said elongate tube , said head assembly further comprising a pair of clamp blades that are mounted to said elongate tube for slidable movement along a first axis that is perpendicular to a second, longitudinal axis of said elongate tube , and that are mounted to said elongate tube for pivotable movement about said first axis; wherein said actuator handle engages said head assembly to cause said head assembly to move through at least one of three distinct degrees of freedom of movement to apply pressure to a patient's tissue.
A method for preparing a tertiary hydroxyl functional alkoxysilane of the general formula (I) wherein R 1 is selected from the group consisting of hydrogen and a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R 2 and R 3 are same or different and are, independent from one another, selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R 4 is selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R 5 is selected from a linear or branched, substituted or unsubstituted C 1 -C 8 alkylene residue; R 6 and R 7 are same or different and are, independent from one another, selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; and n is 1, 2 or 3, said method comprising reacting at least one di-substituted lactone compound and at least one aminosilane having at least one primary or secondary amino group in the presence of a Lewis acid catalyst, wherein said di-substituted lactone compound has the general formula (II) and, wherein said aminosilane is an aminoalkylenealkoxysilane having the general formula (III) R 1 is selected from the group consisting of hydrogen and a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R 2 and R 3 are same or different and are, independent from one another, selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R 4 is selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R 5 is selected from a linear or branched, substituted or unsubstituted C 1 -C 8 alkylene residue; R 6 and R 7 are same or different and are, independent from one another, selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; and n is 1, 2 or 3, said method comprising reacting at least one di-substituted lactone compound and at least one aminosilane having at least one primary or secondary amino group in the presence of a Lewis acid catalyst,
An oral liquid pharmaceutical composition comprising berberine or a pharmaceutically acceptable salt form, pelargonium sidoides, propolis and at least one pharmaceutically acceptable excipient.
A foodstuff conveying and dispensing apparatus, comprising: - a housing ; - at least one feeding device in the housing , on which foodstuffs , in particular baking goods, can be conveyed in a horizontal direction, - a shaft extending vertically to the horizontal direction in the housing , - a motor-driven transport device which travels up and down in the shaft and which is able to be charged with at least one foodstuff by the at least one feeding device , and - a discharging point in or on the housing , the transport device conveying the at least one foodstuff in the direction of said discharging point , wherein the transport device has at least one platform which is able to travel in a vertical direction in the shaft , is pivotable about a horizontal pivot axle , and is able to be charged with at least one foodstuff , characterized in that the pivotable platform is pivotable by means of a stepper motor (32; 27a), and that the platform is configured and pivotably arranged such that it is able to be loaded from two sides, on one hand from the side of said feeding device and on the other hand from the opposite side by means of at least one further feeding device , conveying at least one further foodstuff in horizontal direction, which is likewise part of the apparatus. - a housing ; - at least one feeding device in the housing , on which foodstuffs , in particular baking goods, can be conveyed in a horizontal direction, - a shaft extending vertically to the horizontal direction in the housing , - a motor-driven transport device which travels up and down in the shaft and which is able to be charged with at least one foodstuff by the at least one feeding device , and - a discharging point in or on the housing , the transport device conveying the at least one foodstuff in the direction of said discharging point , wherein the transport device has at least one platform which is able to travel in a vertical direction in the shaft , is pivotable about a horizontal pivot axle , and is able to be charged with at least one foodstuff ,
An oxidative coloring or bleaching agent for keratin fibers, in particular for human hair, containing a) at least one saturated dicarboxylic acid having 2 to 10 carbon atoms and/or at least one salt of said acid(s), b) at least one amino acid of formula (VI) in which X represents a hydrogen atom or a monovalent or divalent cation; n represents zero, 1, 2 or 3; R 1 represents a radical selected from an amino group, a guanidine group, a (1H-imidazol-4-yl) group, a carboxamide group -CONH 2 , a 1H-indol-3-yl group, a thiol group -SH and a methylsulfanyl group -SCH 3 , or at least one salt of said amino acid, c) also at least one alkalizing agent, selected from ammonium hydroxide, monoethanolamine and sodium silicates, and mixtures thereof, d) optionally at least one oxidation dye precursor and/or at least one substantive dye, e) water, and f) at least one peroxide compound. a) at least one saturated dicarboxylic acid having 2 to 10 carbon atoms and/or at least one salt of said acid(s), b) at least one amino acid of formula (VI) in which X represents a hydrogen atom or a monovalent or divalent cation; n represents zero, 1, 2 or 3; R 1 represents a radical selected from an amino group, a guanidine group, a (1H-imidazol-4-yl) group, a carboxamide group -CONH 2 , a 1H-indol-3-yl group, a thiol group -SH and a methylsulfanyl group -SCH 3 , or at least one salt of said amino acid, X represents a hydrogen atom or a monovalent or divalent cation; n represents zero, 1, 2 or 3; R 1 represents a radical selected from an amino group, a guanidine group, a (1H-imidazol-4-yl) group, a carboxamide group -CONH 2 , a 1H-indol-3-yl group, a thiol group -SH and a methylsulfanyl group -SCH 3 , or at least one salt of said amino acid, c) also at least one alkalizing agent, selected from ammonium hydroxide, monoethanolamine and sodium silicates, and mixtures thereof, d) optionally at least one oxidation dye precursor and/or at least one substantive dye, e) water, and f) at least one peroxide compound.
An apparatus for treating dairy manure that removes nitrogen and phosphorus from manure wastewater and discharges to farmland, the apparatus comprising: an anaerobic digester for converting organic matter of dairy manure into methane gas using an anaerobic digestion reaction; a fiber separator for separating fibers present in the organic matter not converted to the methane gas; an aeration tank is configured to supply air to improve the sedimentation and flocculation properties of the micro-solids and to remove some nitrogen and phosphorus by raising the pH of manure wastewater remaining in the treated water after the fibers are separated; a flotation tank for flocculating or floating the micro-solids; a nitritation tank for converting ammonia nitrogen remaining in the treated wastewater after the micro-solids have been removed into nitrite nitrogen; an anammox tank for removing the nitrite nitrogen using a shortcut nitrogen removal reaction; and a sedimentation/storage tank for removing nitrate nitrogen by inducing endogenous denitrification of the nitrate nitrogen, wherein the aeration tank is configured to retain the micro-solids for one to three days, maintain a dissolved oxygen concentration at 1.0 to 2.0 mg/L, and maintain an oxygen utilization rate at 22 to 26 mgO2/L/hr. an anaerobic digester for converting organic matter of dairy manure into methane gas using an anaerobic digestion reaction; a fiber separator for separating fibers present in the organic matter not converted to the methane gas; an aeration tank is configured to supply air to improve the sedimentation and flocculation properties of the micro-solids and to remove some nitrogen and phosphorus by raising the pH of manure wastewater remaining in the treated water after the fibers are separated; a flotation tank for flocculating or floating the micro-solids; a nitritation tank for converting ammonia nitrogen remaining in the treated wastewater after the micro-solids have been removed into nitrite nitrogen; an anammox tank for removing the nitrite nitrogen using a shortcut nitrogen removal reaction; and a sedimentation/storage tank for removing nitrate nitrogen by inducing endogenous denitrification of the nitrate nitrogen, wherein the aeration tank is configured to retain the micro-solids for one to three days, maintain a dissolved oxygen concentration at 1.0 to 2.0 mg/L, and maintain an oxygen utilization rate at 22 to 26 mgO2/L/hr.
A Programmed Cell Death 1 (PD-1) antagonist and a Death Receptor (DR) agonist for use in a method of treating cancer, wherein the DR agonist is an anti-DR5 antibody and the PD-1 antagonist is an anti-PD-1 antibody comprising (i) the CDR1, CDR2 and CDR3 domains in a heavy chain variable region having the sequence set forth in SEQ ID NO: 13, and the CDR1, CDR2 and CDR3 domains in a light chain variable region having the sequence set forth in SEQ ID NO: 15; or (ii) heavy chain variable region CDR1, CDR2 and CDR3 domains having the sequences set forth in SEQ ID NOs: 17, 18 and 19, respectively, and light chain variable region CDR1, CDR2 and CDR3 domains having the sequences set forth in SEQ ID NOs: 20, 21 and 22, respectively; or (iii) heavy and light chain variable regions having the sequences set forth in SEQ ID NOs: 13 and 15, respectively; or (iv) heavy and light chains having the sequences set forth in SEQ ID NOs: 11 and 12, respectively, wherein the anti-DR5 antibody and the anti-PD-1 antibody are for being administered in an amount that inhibits tumor growth in vivo. (i) the CDR1, CDR2 and CDR3 domains in a heavy chain variable region having the sequence set forth in SEQ ID NO: 13, and the CDR1, CDR2 and CDR3 domains in a light chain variable region having the sequence set forth in SEQ ID NO: 15; or (ii) heavy chain variable region CDR1, CDR2 and CDR3 domains having the sequences set forth in SEQ ID NOs: 17, 18 and 19, respectively, and light chain variable region CDR1, CDR2 and CDR3 domains having the sequences set forth in SEQ ID NOs: 20, 21 and 22, respectively; or (iii) heavy and light chain variable regions having the sequences set forth in SEQ ID NOs: 13 and 15, respectively; or (iv) heavy and light chains having the sequences set forth in SEQ ID NOs: 11 and 12, respectively,
Device for removing and crushing, in particular mulching, weeds, undersown crops or the like between crops planted in rows, with a plurality of tools associated with individual rows of plants, which are mounted on a carrier of an agricultural vehicle, characterized in that at least one tool , which tools each have at least one rotating blade , is mounted on or in a tool holder , which tool holder is connected to a tool carrier via a vertical axis and corresponding extensions and side pendulums provided and is articulated movably on the tool carrier , pivoting of the tool holder being prevented by the side pendulums provided on the tool carrier , which are provided on the tool carrier and which are displaceably guided about a substantially horizontal pivot axis oriented in the direction of travel of the vehicle and in the direction of the rows of plants extending substantially parallel to one another, and wherein the tool holders can be guided by means of lateral guide devices , in particular guide plates, at their outer peripheries in the direction of travel (X) of the vehicle through the plants of the rows of plants.
A substrate processing apparatus comprising: a substrate holding apparatus ; and a processing head configured to scrub an upper surface (US) of a substrate (W), the substrate holding apparatus comprises: a substrate holder configured to hold the substrate(W); and a substrate rotating mechanism configured to rotate the substrate(W) held by the substrate holder , characterized in that the substrate holder comprises a holding chuck configured to hold an outermost circumferential surface of the substrate (W), and the substrate holder including the holding chuck is disposed below the upper surface (US) of the substrate (W) so as not to project above the upper surface (US) of the substrate (W) in a state where the substrate (W) is held by the holding chuck . a substrate holding apparatus ; and a processing head configured to scrub an upper surface (US) of a substrate (W), the substrate holding apparatus comprises: a substrate holder configured to hold the substrate(W); and a substrate rotating mechanism configured to rotate the substrate(W) held by the substrate holder , characterized in that a substrate holder configured to hold the substrate(W); and a substrate rotating mechanism configured to rotate the substrate(W) held by the substrate holder , characterized in that the substrate holder comprises a holding chuck configured to hold an outermost circumferential surface of the substrate (W), and the substrate holder including the holding chuck is disposed below the upper surface (US) of the substrate (W) so as not to project above the upper surface (US) of the substrate (W) in a state where the substrate (W) is held by the holding chuck .
Panel for forming skylights in roofing structures, comprising at least one first layer made of a transparent material and at least one reinforcing layer constrained to the surface of said at least one first layer of transparent material , wherein said at least one reinforcing layer comprises at least one net, preferably a metal net, and the panel comprises constraining means for the constraint to said roofing structure , wherein said at least one reinforcing net extends at least partially at said constraining means for the constraint to the roofing structure, said constraining means comprising at least one protruding portion extending laterally from said panel, characterized in that said at least one protruding portion comprises three surfaces according to a substantially U-shaped configuration.
A co-stimulatory domain comprising an amino acid sequence set forth in SEQ ID NO: 8.
Cutting head for a hair clipper with an upper cutter formed by a plurality of webs and slots between the webs , which webs have a contact surface for skin contact and form a shearing surface opposite the contact surface , and with a lower cutter having a plurality of cutting blades , which can be driven to oscillating movement relative to the upper cutter and which is guided to lie against the shearing surface of the upper cutter , wherein at least one of the webs of the upper cutter is designed with an end which is free-standing in the plane of the contact surface , the at least one web with the free-standing end being adjoined by a prong which is different from the upper cutter , characterized in that the at least one web with the free-standing end in the plane of the contact surface is shortened in the direction of the plane of the contact surface , in particular by the length of the extension of the prong , compared to a web having a non-free-standing end in the plane of the contact surface .
Method for restoring license keys (PK1,...,PK10) in a modular automation station comprising a main unit (IM) with a backplane bus connection and a plurality of modules (M1,...,M6) similarly with a backplane bus connection, wherein the modules (M1,...,M6) or the main unit (IM) with the respective backplane bus connection communicate with one another via a backplane bus (RB), wherein the modules (M1,...,M6) are operated by means of a license key (PK1,...,PK10) to provide a software-based functionality (F1,...,F10) tied to the respective license key (PK1,...,PK10), wherein after a module (M3) is replaced with a replacement module (EM), in which the software-based functionality (F3) is not yet enabled, a restoration step is carried out, characterised in that a license key set (PKS) is restored, wherein the license key set (PKS) comprises all license keys (PK1,...,PK10) of the modules (M1,...,M6) of the automation station , for restoring the license key set (PKS), a first data block is read from a first storage location (S1) of the automation station , a second data block is read from a second storage location (S1) of the automation station and a third data block is read from a third storage location (S1) of the automation station , wherein the data blocks comprise data portions (Da,Db) of the license key set (PKS) as follows, the license key set (PKS) is divided into a first part (A) and a second part (B), wherein parity information (P1,P2,P3,P4) is formed from the two parts (A,B) and the data portions (Da,Db) and the parity information (P1,P2,P3,P4) are distributed in a balanced manner over the data blocks , wherein the license key set (PKS) is restored on the basis of the parity information even if only two of the three data blocks could be read and the license key (PK3) for the software-based functionality (F3) of the replaced module (M3) is assigned to the replacement module (EM) and thus the software-based functionality (F1) is enabled for the replacement module (EM).