A method for preparing a twist and seal flexible article, comprising: a) providing a flexible article comprising: i) a front panel and a back panel, each comprising a flexible substrate; ii) wherein the front panel and the back panel each have an inside surface and an outside surface ; iii) the inside surface of the front panel faces the inside surface of the back panel; iv) the front panel and the back panel are joined on three sides, and the fourth side is open; b) providing an adhesive composition; characterized by the step of: c) applying the adhesive composition: i) to the inside surface of the front panel and the inside surface of the back panel; wherein the article can be sealed by a twisting motion that brings the inside surface of the back panel and the inside surface of the front panel into contact that activates the adhesive composition; or ii) to the outside surface of the front panel and the inside surface of the back panel; wherein the article can be sealed by a twisting motion, or by a fold over and twisting motion that brings the outside surface of the front panel and the inside surface of the back panel into contact that activates the adhesive composition; or iii) to the inside surface of the front panel and the outside surface of the back panel; wherein the article can be sealed by a twisting motion, or by a fold over and twisting motion that brings the inside surface of the front panel and the outside surface; or iv) to the outside surface of the front panel and the outside surface of the back panel; wherein the article is inverted (turned inside out) prior to use so that the article can be sealed with a twisting motion that brings the adhesive coated surfaces of the front panel and the back panel into contact that activates the adhesive composition. a) providing a flexible article comprising: i) a front panel and a back panel, each comprising a flexible substrate; ii) wherein the front panel and the back panel each have an inside surface and an outside surface ; iii) the inside surface of the front panel faces the inside surface of the back panel; iv) the front panel and the back panel are joined on three sides, and the fourth side is open; i) a front panel and a back panel, each comprising a flexible substrate; ii) wherein the front panel and the back panel each have an inside surface and an outside surface ; iii) the inside surface of the front panel faces the inside surface of the back panel; iv) the front panel and the back panel are joined on three sides, and the fourth side is open; b) providing an adhesive composition; i) to the inside surface of the front panel and the inside surface of the back panel; wherein the article can be sealed by a twisting motion that brings the inside surface of the back panel and the inside surface of the front panel into contact that activates the adhesive composition; or ii) to the outside surface of the front panel and the inside surface of the back panel; wherein the article can be sealed by a twisting motion, or by a fold over and twisting motion that brings the outside surface of the front panel and the inside surface of the back panel into contact that activates the adhesive composition; or iii) to the inside surface of the front panel and the outside surface of the back panel; wherein the article can be sealed by a twisting motion, or by a fold over and twisting motion that brings the inside surface of the front panel and the outside surface; or iv) to the outside surface of the front panel and the outside surface of the back panel; wherein the article is inverted (turned inside out) prior to use so that the article can be sealed with a twisting motion that brings the adhesive coated surfaces of the front panel and the back panel into contact that activates the adhesive composition. <EOS>