mhurhangee/patent-ind-claim-en huggingface dataset:
An in vitro method for detecting the presence of a recombinant human insulin (rHI) neutralizing antibody by analyzing a serum sample, comprising the steps of: (a) pre-treating the serum sample to dissociate a complex of the antibody with insulin, the pre-treating comprising: i. acid dissociation and charcoal treatment; ii. neutralization and PEG treatment; and iii. pellet re-suspension; (b) performing a cell-based assay, wherein the cell-based assay comprises the steps of: i. seeding of cells having a receptor for rHI; ii. starving the cells for 18 hours to 26 hours in a Glucose free medium; iii. contacting a population of the starved cells with rHI and the pre-treated serum sample; iv. lysing the cells and preparing a clear lysate; and v. evaluating the lysate for phosphorylation of the insulin receptor; and (c) correlating the amount of phosphorylation with a floating cut point, being a level of response where an amount of phosphorylation that is lower than or equal to the floating cut point indicates that the sample contains quantities of a rHI antibody. (a) pre-treating the serum sample to dissociate a complex of the antibody with insulin, the pre-treating comprising: i. acid dissociation and charcoal treatment; ii. neutralization and PEG treatment; and iii. pellet re-suspension; i. acid dissociation and charcoal treatment; ii. neutralization and PEG treatment; and iii. pellet re-suspension; (b) performing a cell-based assay, wherein the cell-based assay comprises the steps of: i. seeding of cells having a receptor for rHI; ii. starving the cells for 18 hours to 26 hours in a Glucose free medium; iii. contacting a population of the starved cells with rHI and the pre-treated serum sample; iv. lysing the cells and preparing a clear lysate; and v. evaluating the lysate for phosphorylation of the insulin receptor; and i. seeding of cells having a receptor for rHI; ii. starving the cells for 18 hours to 26 hours in a Glucose free medium; iii. contacting a population of the starved cells with rHI and the pre-treated serum sample; iv. lysing the cells and preparing a clear lysate; and v. evaluating the lysate for phosphorylation of the insulin receptor; and (c) correlating the amount of phosphorylation with a floating cut point, being a level of response where an amount of phosphorylation that is lower than or equal to the floating cut point indicates that the sample contains quantities of a rHI antibody.
Method for determining phase currents (i a , i b , i c ) of a rotating multiphase electrical machine fed by means of a PWM-controlled inverter, comprising the method steps of: a. determining injection voltages at a time point during one controller sampling period that are applied for drive of the electrical machine in at least one PWM period following this time point, the injection voltages here are composed of specified voltages, which generate a corresponding fundamental wave current, together with additional, high-frequency voltages, b. determining an evaluation direction of a phase current vector of the electrical machine depending on the injection voltages determined in step a and/or on an operating point of the electrical machine and/or on a temperature-dependency of the phase current vector, c. determining, for each of the phase currents (i a , i b , i c ), a number of current measurements that should be carried out in each case in at least one passive switching state of the inverter within the at least one PWM period , depending on the evaluation direction determined in method step b, d. determining the phase currents (i a , i b , i c ) that flow in the at least one PWM period in the electrical machine, depending on the respective number of current measurements determined in method step c. a. determining injection voltages at a time point during one controller sampling period that are applied for drive of the electrical machine in at least one PWM period following this time point, the injection voltages here are composed of specified voltages, which generate a corresponding fundamental wave current, together with additional, high-frequency voltages, b. determining an evaluation direction of a phase current vector of the electrical machine depending on the injection voltages determined in step a and/or on an operating point of the electrical machine and/or on a temperature-dependency of the phase current vector, c. determining, for each of the phase currents (i a , i b , i c ), a number of current measurements that should be carried out in each case in at least one passive switching state of the inverter within the at least one PWM period , depending on the evaluation direction determined in method step b, d. determining the phase currents (i a , i b , i c ) that flow in the at least one PWM period in the electrical machine, depending on the respective number of current measurements determined in method step c.
A sampling face mask for collecting substances exhaled from the nose of a subject, the sampling mask comprises, a mask body having a front side substantially conforms to the shape of the nose of the subject, and a bottom ; a removable cartridge removably coupled to the mask body comprising a cartridge body having a chamber for housing the substances exhaled from the nose of the subject; and characterized by : one or more clamping blocks disposed on the bottom of the mask body; the cartridge body comprising a door disposed above the chamber and adapted for opening or closing the chamber; and the sampling mask further comprising a driving means operably coupled to the mask body, the cartridge body and the door, and configured for driving the door to move laterally or vertically with respect to the cartridge body, thereby opening or closing the chamber, wherein the one or more clamping blocks of the mask body can hold the door in place thereby keeping the door from closing and wherein the chamber is disposed substantially underneath the nose and kept open and when the one or more clamping blocks does not hold the door in place, the door is driven close via the driving means thereby closing the chamber, and allowing the removable cartridge to be separated from the mask body. subject, the sampling mask comprises, a mask body having a front side substantially conforms to the shape of the nose of the subject, and a bottom ; a removable cartridge removably coupled to the mask body comprising a cartridge body having a chamber for housing the substances exhaled from the nose of the subject; and characterized by : one or more clamping blocks disposed on the bottom of the mask body; the cartridge body comprising a door disposed above the chamber and adapted for opening or closing the chamber; and the sampling mask further comprising a driving means operably coupled to the mask body, the cartridge body and the door, and configured for driving the door to move laterally or vertically with respect to the cartridge body, thereby opening or closing the chamber, wherein the one or more clamping blocks of the mask body can hold the door in place thereby keeping the door from closing and wherein the chamber is disposed substantially underneath the nose and kept open and when the one or more clamping blocks does not hold the door in place, the door is driven close via the driving means thereby closing the chamber, and allowing the removable cartridge to be separated from the mask body.
A computer-implemented method for managing data traffic, comprising the steps of connecting at least two telematic devices to a computer system ; managing by the computer system connection of the at least two telematic devices to a communication network for receiving packet-based data and voice data from the communication network by the at least two telematic devices ; and wherein the computer system controls one of the at least two telematic devices to receive the packet-based data from the communication network to run a telematic application on the one of the at least two telematic devices and another one of the at least two telematic devices to receive the voice data from the communication network to run another telematic application on the other one of the at least two telematic devices .
Pistol comprising a firing device arranged in a slide , said device comprising a striker comprising a striker head , characterized in that said striker comprises at least two bearing surfaces arranged perpendicularly to the axis of the striker and in that said device comprises at least two parallel striker springs arranged laterally on the side of the striker axis and bearing on the at least two bearing surfaces .
A method for managing custom code within a data computing platform comprising: determining that a request for one or more uniform resource identifiers external to the data computing platform is being made by custom code executing in the data computing platform; in response to the determination, checking a whitelist of allowable external uniform resource identifiers against the requested one or more uniform resource identifiers; allowing access to the requested one or more uniform resource identifiers if a match is detected with the whitelist, otherwise preventing access by the custom code to the requested one or more uniform resource identifiers; linking a manifest file to a project identifier related to the custom code, the manifest file including the whitelist that lists the allowable uniform resource identifiers that are external to the data computing platform, the allowable uniform resource identifiers being approved to be accessed by the custom code during execution of the custom code; and checking a blacklist of uniform resource identifiers external to the data computing network on a per registered organization level and denying access to a whitelisted uniform resource identifier if the whitelisted uniform resource identifier is on the blacklist, wherein the method is performed using one or more processors. determining that a request for one or more uniform resource identifiers external to the data computing platform is being made by custom code executing in the data computing platform; in response to the determination, checking a whitelist of allowable external uniform resource identifiers against the requested one or more uniform resource identifiers; allowing access to the requested one or more uniform resource identifiers if a match is detected with the whitelist, otherwise preventing access by the custom code to the requested one or more uniform resource identifiers; linking a manifest file to a project identifier related to the custom code, the manifest file including the whitelist that lists the allowable uniform resource identifiers that are external to the data computing platform, the allowable uniform resource identifiers being approved to be accessed by the custom code during execution of the custom code; and checking a blacklist of uniform resource identifiers external to the data computing network on a per registered organization level and denying access to a whitelisted uniform resource identifier if the whitelisted uniform resource identifier is on the blacklist, wherein the method is performed using one or more processors.
A formulation suitable for transdermal delivery of an active agent through the skin, nail or hair follicle of a subject, which formulation comprises at least one active agent in an amount effective for treatment of a condition in said subject and benzyl alcohol is present at 0.5-2% w/w of said formulation; and lecithin organogel is present at 25-70% w/w of said formulation; wherein: i) the formulation further comprises a nonionic surfactant present at 2-25% w/w of said formulation; and a polar solvent at least in an amount in molar excess of the nonionic surfactant; or ii) the formulation is essentially anhydrous and further comprises a nonionic surfactant and a bile salt, wherein the bile salt is present at 1-15% w/w of said formulation and the surfactant is provided in powdered form at 20-60% w/w of said formulation. i) the formulation further comprises a nonionic surfactant present at 2-25% w/w of said formulation; and a polar solvent at least in an amount in molar excess of the nonionic surfactant; or ii) the formulation is essentially anhydrous and further comprises a nonionic surfactant and a bile salt, wherein the bile salt is present at 1-15% w/w of said formulation and the surfactant is provided in powdered form at 20-60% w/w of said formulation.
A curable protective coating composition, comprising a film forming binder, a pigment, a stripping agent, and a solvent, wherein the film forming binder is an organosilicon polymer comprising T-functional and D-functional siloxane units, the molar ratio of T-functional to D-functional siloxane units is from 20:1 to 5:1, and wherein the stripping agent is selected from the group consisting of graphite, a oxide mixture, and combination thereof, in which the oxide mixture comprises, based on the weight of the oxide mixture, 80.0% to 99.9% of Al 2 O 3 , 0.01% to 20% of SiO 2 , 0.001% to 0.5% of Fe 2 O 3 , 0.01% to 1% of CaO, and 0.01% to 1% of MgO.
A temperature increase testing method for a reactor (L1), characterized by comprising: a step (S3) of calculating a target copper loss (Wcut) based on a copper loss (Wcu21) during energization of a fundamental wave current at a predetermined current value and respective copper losses (Wcu22m) during energization of respective harmonic currents of predetermined orders at predetermined current values; a step (S4) of calculating a target iron loss (Wfet) based on an iron loss (Wfe21) during energization of the fundamental wave current and iron losses (Wfe22m) during energization of the respective harmonic currents; a step (S5) of calculating a frequency and a current value of a current that creates the target copper loss (Wcut) and the target iron loss (Wfet), respectively as a test frequency (fex) and a test current value (Iex); and a step (S6) of energizing the reactor (L1) with a test current having the test frequency (fex) and the test current value (Iex), until a temperature of a predetermined part of the reactor (L1) becomes constant. a step (S3) of calculating a target copper loss (Wcut) based on a copper loss (Wcu21) during energization of a fundamental wave current at a predetermined current value and respective copper losses (Wcu22m) during energization of respective harmonic currents of predetermined orders at predetermined current values; a step (S4) of calculating a target iron loss (Wfet) based on an iron loss (Wfe21) during energization of the fundamental wave current and iron losses (Wfe22m) during energization of the respective harmonic currents; a step (S5) of calculating a frequency and a current value of a current that creates the target copper loss (Wcut) and the target iron loss (Wfet), respectively as a test frequency (fex) and a test current value (Iex); and a step (S6) of energizing the reactor (L1) with a test current having the test frequency (fex) and the test current value (Iex), until a temperature of a predetermined part of the reactor (L1) becomes constant.
An apparatus for intraocular lens selection, comprising: a biometer configured to obtain at least two pre-operative ocular measurement parameters for an eye; a user interface configured to obtain a lens selection parameter for the eye; an autorefractor configured to obtain a post-operative refraction of the eye; a memory ; and a processor communicatively coupled to the biometer, the user interface, the autorefractor, and the memory, and configured to: determine an intraocular lens power based on a formula using the at least two pre-operative ocular measurement parameters; determine an estimated error of the formula using a deep learning machine trained on verified post-operative results including post-operative refractions corresponding to intraocular lens powers that are associated with at least two pre-operative ocular measurement parameters; adjust the lens selection parameter based on the estimated error; redetermine a final intraocular lens power based on the formula and the adjusted lens selection parameter; and correlate the at least two pre-operative ocular measurement parameters, the intraocular lens power, and the post-operative refraction as a training set. a biometer configured to obtain at least two pre-operative ocular measurement parameters for an eye; a user interface configured to obtain a lens selection parameter for the eye; an autorefractor configured to obtain a post-operative refraction of the eye; a memory ; and a processor communicatively coupled to the biometer, the user interface, the autorefractor, and the memory, and configured to: determine an intraocular lens power based on a formula using the at least two pre-operative ocular measurement parameters; determine an estimated error of the formula using a deep learning machine trained on verified post-operative results including post-operative refractions corresponding to intraocular lens powers that are associated with at least two pre-operative ocular measurement parameters; adjust the lens selection parameter based on the estimated error; redetermine a final intraocular lens power based on the formula and the adjusted lens selection parameter; and correlate the at least two pre-operative ocular measurement parameters, the intraocular lens power, and the post-operative refraction as a training set. determine an intraocular lens power based on a formula using the at least two pre-operative ocular measurement parameters; determine an estimated error of the formula using a deep learning machine trained on verified post-operative results including post-operative refractions corresponding to intraocular lens powers that are associated with at least two pre-operative ocular measurement parameters; adjust the lens selection parameter based on the estimated error; redetermine a final intraocular lens power based on the formula and the adjusted lens selection parameter; and correlate the at least two pre-operative ocular measurement parameters, the intraocular lens power, and the post-operative refraction as a training set.
Beamforming antenna for multi-carrier transmission with multiple sub-carriers, the beamforming antenna comprising: a number of signal paths configured to transmit and receive communication signals, a calibration signal generator that is configured to generate for the signal paths a number of calibration signals with the sub-carriers of the multi-carrier transmission in the frequency domain, the calibration signals comprising a calibration sub-signal in at least one of the sub-carriers of the respective calibration signal , and a supply element configured to supply the calibration signals to the respective signal paths ; characterized in that when generating a calibration signal , the calibration signal generator is configured to generate for each one of the calibration sub-signals a signal stream, wherein the signal streams are mutually independent orthogonal signal streams or quasi-orthogonal signal streams, and to map the generated signal streams in each case to constellation symbols, and to perform a multi-carrier modulation based on the constellation symbols, and to convert the output of the multi-carrier modulation into a serial stream, wherein the serial stream represents the calibration signal in the time domain. a number of signal paths configured to transmit and receive communication signals, a calibration signal generator that is configured to generate for the signal paths a number of calibration signals with the sub-carriers of the multi-carrier transmission in the frequency domain, the calibration signals comprising a calibration sub-signal in at least one of the sub-carriers of the respective calibration signal , and a supply element configured to supply the calibration signals to the respective signal paths ; characterized in that when generating a calibration signal , the calibration signal generator is configured to generate for each one of the calibration sub-signals a signal stream, wherein the signal streams are mutually independent orthogonal signal streams or quasi-orthogonal signal streams, and to map the generated signal streams in each case to constellation symbols, and to perform a multi-carrier modulation based on the constellation symbols, and to convert the output of the multi-carrier modulation into a serial stream, wherein the serial stream represents the calibration signal in the time domain.
A control device for a vehicle, comprising: a recognition section that is configured to recognize information relating to an outward form of an occupant; and a control section that is configured to execute control, before the occupant boards the vehicle, to adjust a seat position in the vehicle to a specified position that is specified as being an optimal position according to information relating to the vehicle that the occupant is boarding and the information relating to the outward form of the occupant recognized by the recognition section , characterized in that the information relating to the outward form of the occupant includes information relating to a body type of the occupant and clothing of the occupant. a recognition section that is configured to recognize information relating to an outward form of an occupant; and a control section that is configured to execute control, before the occupant boards the vehicle, to adjust a seat position in the vehicle to a specified position that is specified as being an optimal position according to information relating to the vehicle that the occupant is boarding and the information relating to the outward form of the occupant recognized by the recognition section , characterized in that the information relating to the outward form of the occupant includes information relating to a body type of the occupant and clothing of the occupant.