mhurhangee/patent-ind-claim-en huggingface dataset:
Antibody Drug Conjugations (ADCs) with the formula (I) in which n stands for 1 to 8, AK stands for an anti-CD123 antibody, selected from the group consisting of TPP-8987, TPP-9476 and TPP-8988 , or AK stands for an anti-CXCR5 antibody, preferably selected from the group consisting of TPP-9574, TPP-9580 and TPP-9024 , or AK stands for an antigen-binding fragment of these antibodies, wherein the antibody or the antigen-binding fragment is bound by a sulphur atom of a cystein side group, as well as their salts, solvates and salts of these solvates. n stands for 1 to 8, AK stands for an anti-CD123 antibody, selected from the group consisting of TPP-8987, TPP-9476 and TPP-8988 , or AK stands for an anti-CXCR5 antibody, preferably selected from the group consisting of TPP-9574, TPP-9580 and TPP-9024 , or AK stands for an antigen-binding fragment of these antibodies, wherein the antibody or the antigen-binding fragment is bound by a sulphur atom of a cystein side group, as well as their salts, solvates and salts of these solvates.
A roof window comprising a sash and a frame , each of the sash and the frame having two side members, a top member and a bottom member, and delimiting a frame opening and a sash opening, respectively, said sash carrying a pane and being connected to the frame via a hinge device including a pair of hinges defining a hinge axis (α) located between a centre axis and the top of the roof window, such that the hinge axis (α) is positioned close to, or even coinciding with the centre of gravity of the roof window , each hinge (6; 306) of said pair of hinges comprising a sash hinge part and a frame hinge part of substantially equal width, the sash hinge part and the frame hinge part being coupled to each other such that relative movement is allowed, said frame being adapted to be connected to a load-bearing structure of a roof of a building, in which the pane has an exterior surface and an interior surface , and the sash and frame each has an interior side adapted to face the interior of the building in the mounted condition and an exterior side adapted to face the exterior of the building in the mounted condition, wherein the pair of hinges are arranged on either side of the pane between the frame and the sash , and in which the frame comprises a frame recess facing the sash and in which at least part of each hinge is arranged, the frame recess having a frame recess depth (df) and a frame recess width (wf), characterised in that the frame recess (44; 144; 244; 344) is provided with such a frame recess width (wf) that at least 60% of the width of each hinge is arranged in the frame recess.
Multi-functional electrical connection assembly for transmitting medium and high current densities, comprising - a plug socket with three contact openings , - a contact carrier , - three electrically conductive contact elements comprising a round contact plate and a contact pin which protrudes from the contact plate and is arranged eccentrically on the round contact plate , wherein the contact carrier has recesses for receiving the contact elements , and wherein - the connection between each contact pin and each round contact plate is an ultrasonically welded connection. - a plug socket with three contact openings , - a contact carrier , - three electrically conductive contact elements comprising a round contact plate and a contact pin which protrudes from the contact plate and is arranged eccentrically on the round contact plate , wherein the contact carrier has recesses for receiving the contact elements , and wherein - the connection between each contact pin and each round contact plate is an ultrasonically welded connection.
A system for treating a wall of a lung passageway comprising: a catheter comprising at least one electrode disposed near its distal end, wherein the at least one electrode is configured to be positioned within a lumen of the lung passageway so that the at least one electrode is able to transmit energy to a treatment area of the wall of the lung passageway having a collagen matrix structure; and a generator in electrical communication with the at least one electrode, wherein the generator includes at least one energy delivery algorithm configured to provide an electric signal of the energy for a treatment duration to the treatment area while maintaining the collagen matrix structure within the treatment area so as to provide a treatment of a condition of the lung passageway, and characterized in that the electric signal has a waveform comprising distinct energy packets. a catheter comprising at least one electrode disposed near its distal end, wherein the at least one electrode is configured to be positioned within a lumen of the lung passageway so that the at least one electrode is able to transmit energy to a treatment area of the wall of the lung passageway having a collagen matrix structure; and a generator in electrical communication with the at least one electrode, wherein the generator includes at least one energy delivery algorithm configured to provide an electric signal of the energy for a treatment duration to the treatment area while maintaining the collagen matrix structure within the treatment area so as to provide a treatment of a condition of the lung passageway, and characterized in that the electric signal has a waveform comprising distinct energy packets.
Rewinding machine comprising one drive unit for supplying a paper veil , one winding unit for winding the paper veil supplied by the drive unit into a coil (W) around a winding core comprising a primary roller , a secondary roller rotating in contact with the core that is being wound, and a pressure unit equipped with a pressure roller (A, B, C) rotating on to the coil (W) that is being formed, one core exchange unit for ejecting a formed coil (W) from the machine at the end of a winding cycle and inserting one new core to be wound, separation means for interrupting the continuity of the paper veil at the end of a winding cycle, means for winding a drawing flap of the veil on the new core at the start of a new winding cycle, wherein said pressure unit comprises at least two motorized pressure rollers (A, B, C) arranged to alternate in position with respect to the coil (W) and rotate simultaneously while being in contact with the coil that is being formed, at least during part of the winding phase, both having a peripheral speed that is substantially equal to the winding speed of the veil , characterized in that said pressure unit comprises three pressure rollers (A, B, C) with respective rotation axes (A1, B1, C1) integral with a common rotation axis . one drive unit for supplying a paper veil , one winding unit for winding the paper veil supplied by the drive unit into a coil (W) around a winding core comprising a primary roller , a secondary roller rotating in contact with the core that is being wound, and a pressure unit equipped with a pressure roller (A, B, C) rotating on to the coil (W) that is being formed, one core exchange unit for ejecting a formed coil (W) from the machine at the end of a winding cycle and inserting one new core to be wound, separation means for interrupting the continuity of the paper veil at the end of a winding cycle, means for winding a drawing flap of the veil on the new core at the start of a new winding cycle, wherein said pressure unit comprises at least two motorized pressure rollers (A, B, C) arranged to alternate in position with respect to the coil (W) and rotate simultaneously while being in contact with the coil that is being formed, at least during part of the winding phase, both having a peripheral speed that is substantially equal to the winding speed of the veil , characterized in that said pressure unit comprises three pressure rollers (A, B, C) with respective rotation axes (A1, B1, C1) integral with a common rotation axis .
Shaft shredder 1 with a machine frame and a shredding unit which comprises at least one shredder shaft mounted therein and driven via a drive, wherein a material delivery region is formed adjacent the shredding unit and comprises a plurality of side walls wherein at least one of the side walls , in particular at least one side wall arranged at the end side in relation to the axial direction of the shredder shaft , can be brought, in particular folded or displaced, from an operative position into a maintenance position, characterised in that in the maintenance position bearing and/or coupling areas of the at least one shredder shaft are accessible wherein the at least one shredder shaft can be dismantled by a releasable form-locking coupling, in particular a screw-on flange coupling (15, 16; 17, 18) at each end of the shredder shaft in a mainly vertical direction from a shredder housing of the shredding unit and the bearings of the shafts remain on or in the shredder housing.
A process to produce an implant , especially an intraluminal endoprosthesis, with a body containing metal material, preferably iron, especially an iron alloy, this process comprising the following steps: a) Preparing the body of the implant ; b) Producing a pore structure with at least some closed pores in one part of the near-surface structure of the implant body; c) Incorporating NOx into the hollow spaces of the pore structure; characterized in that the pore structure is produced by means of heat treatment of the implant body in an oxygen-containing and/or carbon-containing atmosphere. a) Preparing the body of the implant ; b) Producing a pore structure with at least some closed pores in one part of the near-surface structure of the implant body; c) Incorporating NOx into the hollow spaces of the pore structure; characterized in that the pore structure is produced by means of heat treatment of the implant body in an oxygen-containing and/or carbon-containing atmosphere.
A thermoplastic elastomer compound comprising: (a) high vinyl styrene-(ethylene/butylene)-styrene block copolymer having a vinyl content of greater than 50 mole percent and having a Copolymer Tan Delta Peak Temperature, the high vinyl styrene-(ethylene/butylene)-styrene block copolymer has a weight average molecular weight ranging from 200,000 to 1 million; and (b) tackifier having a softening point of at least 80 °C according to ASTM 6493; and wherein the compound has a Compound Tan Delta Peak Temperature, and the Compound Tan Delta Peak Temperature is greater than the Copolymer Tan Delta Peak Temperature. (a) high vinyl styrene-(ethylene/butylene)-styrene block copolymer having a vinyl content of greater than 50 mole percent and having a Copolymer Tan Delta Peak Temperature, the high vinyl styrene-(ethylene/butylene)-styrene block copolymer has a weight average molecular weight ranging from 200,000 to 1 million; and (b) tackifier having a softening point of at least 80 °C according to ASTM 6493; and wherein the compound has a Compound Tan Delta Peak Temperature, and the Compound Tan Delta Peak Temperature is greater than the Copolymer Tan Delta Peak Temperature.
A valvetrain for an internal combustion engine of a type that has a combustion chamber, and a moveable valve having a seat formed in the combustion chamber, comprising: a rocker shaft ; a camshaft ; a rocker arm assembly comprising a cam follower configured to engage a cam mounted on the camshaft as the camshaft rotates and a first rocker arm pivotally mounted on the rocker shaft ; and an electromagnetic latch assembly comprising an electromagnet and a pin that translates between a first position and a second position to alter a configuration of the rocker arm assembly; wherein the electromagnetic latch assembly is powered by a circuit that passes through the rocker shaft . a rocker shaft ; a camshaft ; a rocker arm assembly comprising a cam follower configured to engage a cam mounted on the camshaft as the camshaft rotates and a first rocker arm pivotally mounted on the rocker shaft ; and an electromagnetic latch assembly comprising an electromagnet and a pin that translates between a first position and a second position to alter a configuration of the rocker arm assembly; wherein the electromagnetic latch assembly is powered by a circuit that passes through the rocker shaft .
A light engine for reducing stress and anxiety in animals comprising; a light emitter that emits a UVA1 light having a wavelength in a first range of 360 nm to 400 nm; a light element that emits green light having a wavelength in a second range of 490 nm to 580 nm; and a controller coupled to the light emitter and the light element, the controller configured to control the duration and intensity of the UVA1 light emitted by the light emitter and the duration and intensity of the green light emitted by the light element; characterized in that the percent of UVA1 light compared to the total light output from the light engine is 10% or more, wherein the amount of UVA1 light and green light emitted is at least 75% of the spectral output of the light engine. a light emitter that emits a UVA1 light having a wavelength in a first range of 360 nm to 400 nm; a light element that emits green light having a wavelength in a second range of 490 nm to 580 nm; and a controller coupled to the light emitter and the light element, the controller configured to control the duration and intensity of the UVA1 light emitted by the light emitter and the duration and intensity of the green light emitted by the light element; characterized in that the percent of UVA1 light compared to the total light output from the light engine is 10% or more, wherein the amount of UVA1 light and green light emitted is at least 75% of the spectral output of the light engine.
A prosthetic mitral valve comprising: a valve frame configured to expand from a collapsed configuration to an expanded configuration and having a proximal anchor , a distal anchor , and a central portion therebetween; and the proximal anchor , distal anchor and central portion being formed of wire, the wire being joined at joints; a plurality of leaflets secured to the valve frame; characterized in that the valve frame further has a plurality of curved retention hooks located on the distal anchor to extend toward the center of the frame from joints of the distal anchor when the valve frame is in the expanded configuration, the plurality of retention hooks being configured to flatten and collapse when the valve frame is in the collapsed configuration. a valve frame configured to expand from a collapsed configuration to an expanded configuration and having a proximal anchor , a distal anchor , and a central portion therebetween; and the proximal anchor , distal anchor and central portion being formed of wire, the wire being joined at joints; a plurality of leaflets secured to the valve frame; characterized in that the valve frame further has a plurality of curved retention hooks located on the distal anchor to extend toward the center of the frame from joints of the distal anchor when the valve frame is in the expanded configuration, the plurality of retention hooks being configured to flatten and collapse when the valve frame is in the collapsed configuration.
Device for attaching a cabin (A, B) designed to be hauled by a cable , comprising attachment means to couple the device to the cable according to a coupling axis extending along the cable , at least one arm configured to attach the cabin (A, B) in removable manner and mounted mobile on the attachment means to move the cabin (A, B) with respect to the attachment means , characterized in that it comprises at least one slide fixed to the attachment means , and in that said at least one arm is mounted sliding in said at least one slide along an axis perpendicular to the coupling axis of the attachment means and perpendicular to the vertical axis in a position where the attachment means is coupled to the cable.
A method for indexing handwritten information, comprising a step of providing a user with a collection of stationery products each bearing a color and a machine-readable code that is uniquely associated with the color, steps of taking handwritten notes by said user, each on a different product in the collection selected by the user based on the color borne by said product, taking photographs of the products showing the notes which are taken with a sensor incorporated in a mobile device, steps of decoding the machine-readable codes so as to determine their respective values and storing the photographs in a memory with indexing of said images depending on the value of the code.
Medical instrument having a surface coating , comprising an interference filter having at least one dielectric layer and at least one metallic layer (12, 12-1, 12-2) arranged one above another, wherein: - in a first state the surface coating has a first spectral reflectivity ; - the at least one metallic layer (12, 12-1, 12-2) and/or the at least one dielectric layer are/is configured to be structurally altered by the influence of the corrosive environment on the surface coating , as a result of which the surface coating is able to be converted into a second state; and - in the second state the surface coating has a second spectral reflectivity , which is different from the first spectral reflectivity , - the interference filter comprises a plurality of dielectric layers and/or a plurality of metallic layers . - in a first state the surface coating has a first spectral reflectivity ; - the at least one metallic layer (12, 12-1, 12-2) and/or the at least one dielectric layer are/is configured to be structurally altered by the influence of the corrosive environment on the surface coating , as a result of which the surface coating is able to be converted into a second state; and - in the second state the surface coating has a second spectral reflectivity , which is different from the first spectral reflectivity , - the interference filter comprises a plurality of dielectric layers and/or a plurality of metallic layers .
A discharge section for a discharge of products with at least one suspension element , in particular, for sausage-shaped products, along the discharge section , the discharge section comprising a catcher unit and a guide unit , wherein - the catcher unit comprises a catching end and is configured for catching at least one suspension element of the product with the catching end , and - the guide unit is configured for receiving the at least one suspension element of the product from the catcher unit and for transporting the product at its at least one suspension element along the discharge section , characterized in that the catcher unit and the guide unit are releasably attached to each other by means of an attachment mechanism , the attachment mechanism being configured to enable an adjustment of a position of the catcher unit's catching end relative to the guide unit . - the catcher unit comprises a catching end and is configured for catching at least one suspension element of the product with the catching end , and - the guide unit is configured for receiving the at least one suspension element of the product from the catcher unit and for transporting the product at its at least one suspension element along the discharge section , characterized in that the catcher unit and the guide unit are releasably attached to each other by means of an attachment mechanism , the attachment mechanism being configured to enable an adjustment of a position of the catcher unit's catching end relative to the guide unit .
A display apparatus comprising: a display panel configured to display an image in a forward direction thereof; a bezel disposed on an edge of the display panel ; and a light refraction member disposed in front of the bezel , the light refraction member including a transparent material, and configured to refract outside light, coming from a rear side of the display apparatus and obliquely inclined with respect to the forward direction, in the forward direction, wherein the bezel comprises a front part which covers edge portions of a front surface of the display panel and an edge part which covers side surfaces of the display panel , and the light refraction member includes a refraction surface disposed to be inclined relative to the forward direction from the front part of the bezel to the edge part of the bezel , wherein the refraction surface refracts the light coming from the rear side of the display apparatus and obliquely inclined with respect to the forward direction in the forward direction of the bezel; and a front end of the refraction surface is disposed further outward than the bezel ; and the rear end of the refraction surface is disposed on a region of the edge of the display panel and characterized in that the display apparatus further comprises a reflection member provided between a front side of the bezel and the light refraction member . a display panel configured to display an image in a forward direction thereof; a bezel disposed on an edge of the display panel ; and a light refraction member disposed in front of the bezel , the light refraction member including a transparent material, and configured to refract outside light, coming from a rear side of the display apparatus and obliquely inclined with respect to the forward direction, in the forward direction, wherein the bezel comprises a front part which covers edge portions of a front surface of the display panel and an edge part which covers side surfaces of the display panel , and the light refraction member includes a refraction surface disposed to be inclined relative to the forward direction from the front part of the bezel to the edge part of the bezel , wherein the refraction surface refracts the light coming from the rear side of the display apparatus and obliquely inclined with respect to the forward direction in the forward direction of the bezel; and a front end of the refraction surface is disposed further outward than the bezel ; and the rear end of the refraction surface is disposed on a region of the edge of the display panel and characterized in that the display apparatus further comprises a reflection member provided between a front side of the bezel and the light refraction member .
A method for providing railway safety, comprising: communicating between a personal alert device configured to be worn by a rail worker and a vehicle alert device disposed on a rail vehicle , the vehicle alert device and the personal alert device each having: a first radio ; and a second radio , the first radios (24. 34) configured to operate at a different frequency from the second radios ; operating the first radios of the personal alert device and the vehicle alert device at a first frequency to provide data communication between the rail worker and the rail vehicle ; operating the second radios of the personal alert device and the vehicle alert device at a second frequency to perform a ranging function; and operating the second radios to also provide a redundant data communication channel between the rail worker and the rail vehicle . communicating between a personal alert device configured to be worn by a rail worker and a vehicle alert device disposed on a rail vehicle , the vehicle alert device and the personal alert device each having: a first radio ; and a second radio , the first radios (24. 34) configured to operate at a different frequency from the second radios ; a first radio ; and a second radio , the first radios (24. 34) configured to operate at a different frequency from the second radios ; operating the first radios of the personal alert device and the vehicle alert device at a first frequency to provide data communication between the rail worker and the rail vehicle ; operating the second radios of the personal alert device and the vehicle alert device at a second frequency to perform a ranging function; and operating the second radios to also provide a redundant data communication channel between the rail worker and the rail vehicle .