mhurhangee/patent-ind-claim-en huggingface dataset:
A method to obtain a composition comprising 1-amino-3-[ 18 F]-fluorocyclobutanecarboxylic acid ([ 18 F]-FACBC) wherein said composition comprises acetonitrile (MeCN) at a concentration of no greater than 50 μg/mL and wherein said composition has a radioactive concentration (RAC) of between 500-5000 MBq/ml wherein said method comprises: (i) reacting in a reaction vessel [ 18 F]fluoride with a precursor compound of Formula I: wherein: LG is a leaving group; PG 1 is carboxy protecting group; and, PG 2 is an amine protecting group; wherein said reacting step is carried out in acetonitrile; to obtain a reaction mixture comprising a compound of Formula II: wherein: PG 1 and PG 2 are as defined for Formula I; (ii) transferring said compound of Formula II out of said reaction vessel onto a solid phase extraction (SPE) column; (iii) carrying out removal of PG 1 on the SPE column to thereby obtain a compound of Formula III while simultaneously applying heat to the empty reaction vessel: wherein PG 2 is as defined for Formula I; and, (iv) transferring said compound of Formula III back into said heat treated reaction vessel to carry out removal of PG 2 and thereby obtain [ 18 F]-FACBC. (i) reacting in a reaction vessel [ 18 F]fluoride with a precursor compound of Formula I: wherein: LG is a leaving group; PG 1 is carboxy protecting group; and, PG 2 is an amine protecting group; wherein said reacting step is carried out in acetonitrile; to obtain a reaction mixture comprising a compound of Formula II: wherein: PG 1 and PG 2 are as defined for Formula I; LG is a leaving group; PG 1 is carboxy protecting group; and, PG 2 is an amine protecting group; wherein said reacting step is carried out in acetonitrile; to obtain a reaction mixture comprising a compound of Formula II: wherein: PG 1 and PG 2 are as defined for Formula I; (ii) transferring said compound of Formula II out of said reaction vessel onto a solid phase extraction (SPE) column; (iii) carrying out removal of PG 1 on the SPE column to thereby obtain a compound of Formula III while simultaneously applying heat to the empty reaction vessel: wherein PG 2 is as defined for Formula I; and, (iv) transferring said compound of Formula III back into said heat treated reaction vessel to carry out removal of PG 2 and thereby obtain [ 18 F]-FACBC.
An inhaler article comprising: a body extending along a longitudinal center axis (A) from a mouthpiece end to a distal end ; a capsule cavity defined within the body; and a distal end element disposed at the distal end of the inhaler article and extending to the capsule cavity, the distal end element comprising an element distal end , an element inner end , a solid core portion , and at least two grooves , wherein the solid core portion comprises a central portion of the distal end element, wherein the central portion is solid and extends along the longitudinal center axis from the element distal end to the element inner end, wherein the at least two grooves are helical grooves that rotate about the solid core portion along the longitudinal center axis from the element distal end to the element inner end, and wherein the at least two helical grooves extend along an outer surface of the distal end element. a body extending along a longitudinal center axis (A) from a mouthpiece end to a distal end ; a capsule cavity defined within the body; and a distal end element disposed at the distal end of the inhaler article and extending to the capsule cavity, the distal end element comprising an element distal end , an element inner end , a solid core portion , and at least two grooves , wherein the solid core portion comprises a central portion of the distal end element, wherein the central portion is solid and extends along the longitudinal center axis from the element distal end to the element inner end, wherein the at least two grooves are helical grooves that rotate about the solid core portion along the longitudinal center axis from the element distal end to the element inner end, and wherein the at least two helical grooves extend along an outer surface of the distal end element.
Method for monitoring the diffusion of a fluorescent marker within a biological tissue , this method comprising at least one operation of acquiring fluorescence images, using a camera, each operation of acquiring fluorescence images comprising capturing and storing at least one image of fluorescence in a region of the biological tissue and each fluorescence image corresponding to a set of pixels, a relative value of a signal that is representative of the intensity of the fluorescence emission at a point in the region of the biological tissue being associated with at least certain pixels, characterized in that it comprises, during the same operation of perfusion of the fluorescent marker, a step consisting in automatically determining, after comparing the area of diffusion of the biological marker measured in at least two fluorescence images, whether all or part at least one of these fluorescence images for which the diffusion area has been measured must be displayed.
An ultrasound imaging system operable in different tissue specific modes of operation comprising: an ultrasound probe adapted to acquire ultrasound image signals; a beamformer adapted to receive ultrasound image signals and produce coherent echo signals; a B mode image processor , coupled to the beamformer, which is adapted to produce B mode ultrasound images; a Doppler processor , coupled to the beamformer, which is adapted to produce color Doppler image signals; a user interface that in response to user inputs is adapted to control operation of the ultrasound imaging system and which is further adapted to control display and workflow settings of the system; a tissue specific preset (TSP) settings controller adapted to optimize operation of the ultrasound imaging system for settings of different TSP modes of operation based on implementing for each of the different TSP modes default display and workflow settings pre-stored for the TSP mode; a display adapted to display ultrasound images optimized by different TSP settings; and a user control adapted to enable a user to choose either to save one or more display and workflow settings upon a change of TSP mode or to reset display and workflow settings to the default values for the new TSP mode upon a change of TSP mode, wherein the TSP settings controller is configured to maintain display and workflow settings of the system during a change of the TSP mode to a different TSP mode or to reset one or more of the display or workflow settings upon a change of the TSP mode to the default settings for the new TSP mode, in accordance the user choice at the user control. an ultrasound probe adapted to acquire ultrasound image signals; a beamformer adapted to receive ultrasound image signals and produce coherent echo signals; a B mode image processor , coupled to the beamformer, which is adapted to produce B mode ultrasound images; a Doppler processor , coupled to the beamformer, which is adapted to produce color Doppler image signals; a user interface that in response to user inputs is adapted to control operation of the ultrasound imaging system and which is further adapted to control display and workflow settings of the system; a tissue specific preset (TSP) settings controller adapted to optimize operation of the ultrasound imaging system for settings of different TSP modes of operation based on implementing for each of the different TSP modes default display and workflow settings pre-stored for the TSP mode; a display adapted to display ultrasound images optimized by different TSP settings; and a user control adapted to enable a user to choose either to save one or more display and workflow settings upon a change of TSP mode or to reset display and workflow settings to the default values for the new TSP mode upon a change of TSP mode, wherein the TSP settings controller is configured to maintain display and workflow settings of the system during a change of the TSP mode to a different TSP mode or to reset one or more of the display or workflow settings upon a change of the TSP mode to the default settings for the new TSP mode, in accordance the user choice at the user control.
A shift lever mounting bracket comprising: a vehicle-side fixing plate having a virtually flat shape; a lever-side fixing plate having a virtually flat shape; a connecting plate having a virtually flat shape, and extending virtually parallel to both a direction orthogonal to the vehicle-side fixing plate and a direction orthogonal to the lever-side fixing plate ; a vehicle-side bend part connecting a part of an edge of the vehicle-side fixing plate with a part of an edge of the connecting plate; and a lever-side bend part connecting a part of an edge of the lever-side fixing plate and a part of the edge of the connecting plate, wherein an entirety of the shift lever mounting bracket is constituted with a continuous flat plate which is shaped by pressing and bending, wherein the direction orthogonal to the vehicle-side fixing plate and the direction orthogonal to the lever-side fixing plate cross each other. a vehicle-side fixing plate having a virtually flat shape; a lever-side fixing plate having a virtually flat shape; a connecting plate having a virtually flat shape, and extending virtually parallel to both a direction orthogonal to the vehicle-side fixing plate and a direction orthogonal to the lever-side fixing plate ; a vehicle-side bend part connecting a part of an edge of the vehicle-side fixing plate with a part of an edge of the connecting plate; and a lever-side bend part connecting a part of an edge of the lever-side fixing plate and a part of the edge of the connecting plate, wherein an entirety of the shift lever mounting bracket is constituted with a continuous flat plate which is shaped by pressing and bending, wherein the direction orthogonal to the vehicle-side fixing plate and the direction orthogonal to the lever-side fixing plate cross each other.
A vacuum double structure comprising: a tubular and metal inner wall member ; a tubular and metal outer wall member in which the inner wall member is accommodated; and a sealing member provided between a facing surface of the inner wall member and a facing surface of the outer wall member , wherein the sealing member maintains a space between the inner wall member and the outer wall member in a vacuum state; characterised in that the sealing member includes an annular spacer , a first annular packing material , and a second annular packing material ; the annular spacer is provided between the facing surface of the inner wall member and the facing surface of the outer wall member ; the first annular packing material is accommodated in a first groove formed on a first opposed surface of the spacer with respect to the facing surface of the inner wall member and abuts with the facing surface of the inner wall member ; and the second annular packing material is accommodated in a second groove formed on a second opposed surface of the spacer with respect to the facing surface of the outer wall member and abuts with the facing surface of the outer wall member . a tubular and metal inner wall member ; a tubular and metal outer wall member in which the inner wall member is accommodated; and a sealing member provided between a facing surface of the inner wall member and a facing surface of the outer wall member , wherein the sealing member maintains a space between the inner wall member and the outer wall member in a vacuum state; characterised in that the sealing member includes an annular spacer , a first annular packing material , and a second annular packing material ; the annular spacer is provided between the facing surface of the inner wall member and the facing surface of the outer wall member ; the first annular packing material is accommodated in a first groove formed on a first opposed surface of the spacer with respect to the facing surface of the inner wall member and abuts with the facing surface of the inner wall member ; and the second annular packing material is accommodated in a second groove formed on a second opposed surface of the spacer with respect to the facing surface of the outer wall member and abuts with the facing surface of the outer wall member .
An electronic device comprising: a metallic plane comprising an opening ; and a radiofrequency communication or energy transfer antenna made of a planar conductive winding , wherein the planar winding is placed within said opening , one of the two ends of the planar winding being directly connected to the metal plane which continuously surrounds the planar winding, the opening of the metal plane being adapted to receive a camera, a microphone, or a light sensor. a metallic plane comprising an opening ; and a radiofrequency communication or energy transfer antenna made of a planar conductive winding , wherein the planar winding is placed within said opening , one of the two ends of the planar winding being directly connected to the metal plane which continuously surrounds the planar winding, the opening of the metal plane being adapted to receive a camera, a microphone, or a light sensor.
A process for making flour, comprising: (i) combining a wet-milled whole corn fraction composed of endosperm, germ and aleurone-bran with at least one enzyme selected from the group consisting of an endoamylase and endoxylanase, to produce an enzyme-added fraction; (ii) moist-heat precooking said enzyme-added fraction to obtain a pre-cooked enzyme-added fraction; (iii) high-solid conditioning said precooked enzyme-added fraction to partially hydrolyze starchy endosperm and aleurone-bran granules to produce acidic xylooligosaccahrides in enzymatically conditioned corn kernel particles; and (iv) milling said conditioned corn kernel particles to obtain flour. (i) combining a wet-milled whole corn fraction composed of endosperm, germ and aleurone-bran with at least one enzyme selected from the group consisting of an endoamylase and endoxylanase, to produce an enzyme-added fraction; (ii) moist-heat precooking said enzyme-added fraction to obtain a pre-cooked enzyme-added fraction; (iii) high-solid conditioning said precooked enzyme-added fraction to partially hydrolyze starchy endosperm and aleurone-bran granules to produce acidic xylooligosaccahrides in enzymatically conditioned corn kernel particles; and (iv) milling said conditioned corn kernel particles to obtain flour.
Method for supporting the load of a line section to be severed from a line by using a device for supporting the load of a line section to be severed from a line , comprising at least one holding element to be fastened to the line in a force-transmitting manner, a carrier arm fastened to the at least one holding element in a force-transmitting manner and having a pulling means , which can be connected to the line section to be severed in order to support the load of the same, in which at least one holding element of the device is fastened to the line in a force-transmitting manner, and the pulling means is connected to the line section to be severed.
A method for controlling an orthopedic device with an upper part and a lower part , which are connected to each other by a joint device so as to be pivotable about a joint axis and have fastening devices with which the orthopedic device can be secured to a limb, and with an actuator , which is secured to the upper part and the lower part at fastening points and influences a pivoting of the upper part relative to the lower part , and with at least one sensor coupled to a controller which activates or deactivates an adjustment device for adjusting an extension stop that limits a maximum joint angle, wherein the extension stop , in accordance with sensor data, is moved from a starting position, in which the upper part is located in a position of flexion relative to the lower part , to an end position, in which the upper part is located, relative to the lower part , in a position different than the starting position, characterized in that, when the extension stop is reached, the moment effective about the joint axis or the force effective between the upper part and the lower part is measured, and, if a threshold value is exceeded, the extension stop is moved in the direction of its end position, and, if the threshold value is not reached, the extension stop is moved in the opposite direction.
The process for the preparation of Quinazolinyl-xanthine of Formula 4 comprising reacting the compound Acetylphenylamino-But-Br-Me-xanthine of Formula 5 in an alcohol or in an aromatic hydrocarbon solvent using ammonia or an ammonium salt as N-source according to Scheme 9:
Downpipe sensor for single seed identification of seeds (S) in a downpipe having a predetermined measuring field (M), on which a transmitting device and a receiving device are arranged spaced with respect to one another, wherein the light beams (LS) that are emitted by the transmitting device are guided in the case of a clear beam path through the downpipe interior space to the receiving device and in the event of a seed (S) passing through, said light beams are at least in part attenuated, and wherein the receiving device is formed from a line element that comprises a predetermined number of receiving elements , characterised in that the transmitting device comprises one or multiple light-emitting diodes , which are arranged in a line and have perforated screens , and a prism-shaped reflector element that is embodied as a right-angled triangle in which the two surfaces that are perpendicular to one another form an entrance surface and exit surface and the third surface forms a reflection surface and the light beams (LS) are emitted by the light diodes transverse with respect to a receiving axis (E) of the receiving device and are bundled via the perforated screens and are subsequently guided via the entrance surface into the reflector element and are deflected via the reflection surface of said reflector element by means of total internal reflection towards the exit surface to form a light band (LB) of light beams (LS) that are oriented parallel with the result that the light band (LB) in the measuring field (M) entirely illuminates the entire downpipe interior space with an approximately identical intensity and said light band enters parallel to the receiving axis (E) of the receiving device , wherein the entire width of the downpipe interior space and therefore the light band (LB) is completely captured via the line element of said receiving device and that means are provided for the identification of surfaces of seeds (S) that are arranged in the light band (LB).
A method of manufacturing a tyre tread , the tread comprising a tread base and a number of lugs , each of which projects upwards from the tread base and extends substantially crosswise to a travelling direction of the tyre, the method comprising the steps of: (a) proving a tyre casing and tread belts ; (b) arranging a plurality of rubber blocks onto said tread belts , each of said rubber blocks being configured to make a respective lug of the final tread ; (c) winding a rubber ribbon about said rubber blocks and tread belts arranged onto a drum so as to shield said rubber blocks ; (d) curing said rubber blocks together with said wound ribbon in a curing mould negatively reproducing a desired pattern of the tread . (a) proving a tyre casing and tread belts ; (b) arranging a plurality of rubber blocks onto said tread belts , each of said rubber blocks being configured to make a respective lug of the final tread ; (c) winding a rubber ribbon about said rubber blocks and tread belts arranged onto a drum so as to shield said rubber blocks ; (d) curing said rubber blocks together with said wound ribbon in a curing mould negatively reproducing a desired pattern of the tread .
A coated substrate , comprising: a substrate ; and a barrier coating comprising a compound having the formula: LnzABOs where Ln comprises scandium, yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, or mixtures thereof; A comprises Si, Ti, Ge, Sn, Ce, Hf, Zr, or a combination thereof; and B comprises Mo or a combination of Mo with W, wherein the substrate comprises a ceramic matrix composite (CMC), and wherein the coated substrate further comprises a bond coat layer positioned between the substrate and the barrier coating . a substrate ; and a barrier coating comprising a compound having the formula: LnzABOs where Ln comprises scandium, yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, or mixtures thereof; A comprises Si, Ti, Ge, Sn, Ce, Hf, Zr, or a combination thereof; and B comprises Mo or a combination of Mo with W, wherein the substrate comprises a ceramic matrix composite (CMC), and wherein the coated substrate further comprises a bond coat layer positioned between the substrate and the barrier coating .
A set of panels comprising a first panel with a first main plane and a second panel with a second main plane, wherein a first edge of the first panel is configured to be locked to a second edge of the second panel, wherein the first main plane is essentially perpendicular to the second main plane, and wherein the first and the second edges are locked in a first direction (D1), which is perpendicular to the first main plane, and a second direction (D2), which is perpendicular to the second main plane, wherein the first edge comprises an edge tongue , with a longitudinal direction along the first edge, comprising a bottom edge , a first surface and an opposite second surface , wherein the second edge comprises an edge groove , with a longitudinal direction along the second edge, comprising a bottom , a first surface and an opposite second surface , wherein the edge tongue is configured to cooperate with the edge groove for locking together the first and the second edges in the first direction (D1), wherein the first surface of the edge tongue is configured to cooperate, at a longitudinal central part of the first edge and the second edge, with the first surface of the edge groove for said locking in the first direction (D1), wherein the first panel comprises a third edge which is adjacent to the first edge and the second panel comprises a fourth edge which is adjacent to the second edge, and wherein the edge groove extends to the fourth edge , characterized in : • that a second distance , which is between the bottom edge and the bottom and at an edge part of the first edge and the second edge at the third and fourth edges , is greater than a first distance , which is between the bottom edge and the bottom and at the longitudinal central part , in a locked position of the first and the second edges, • such that a greater force, is absorbed by the longitudinal central part than by the edge part , when a load is applied to the first and/or the second panel . • that a second distance , which is between the bottom edge and the bottom and at an edge part of the first edge and the second edge at the third and fourth edges , is greater than a first distance , which is between the bottom edge and the bottom and at the longitudinal central part , in a locked position of the first and the second edges, • such that a greater force, is absorbed by the longitudinal central part than by the edge part , when a load is applied to the first and/or the second panel .
A heating element comprising: a substrate; a conductive heating pattern provided on the substrate; and the cured pattern provided on the conductive heating pattern, wherein the cured pattern comprises a derivative in which an acid generated by a thermal acid generator and an epoxy group of an aromatic epoxy resin form bonds; and an organic dye. a substrate; a conductive heating pattern provided on the substrate; and the cured pattern provided on the conductive heating pattern, wherein the cured pattern comprises a derivative in which an acid generated by a thermal acid generator and an epoxy group of an aromatic epoxy resin form bonds; and an organic dye.