A device for placement in vessels, appendages, and openings in a body, the device comprising: a self-expanding frame having a proximal end , a distal end , and a longitudinal axis, the self-expanding frame including: a face portion having a pre-loaded flat configuration and (i) a center frame portion arranged at the proximal end and (ii) a plurality of elongate members extending from the center frame portion , the self-expanding frame lacking any eyelet that extends beyond the face portion , and a body portion ; and a membrane attached to the self-expanding frame ; wherein the plurality of elongate members are configured to bend or flex in a plane orthogonal to the longitudinal axis and mitigate longitudinal movement of the face portion in response to a compressive force applied to the body portion of the self-expanding frame , wherein the center frame portion is formed by a plurality of arcs defining an inner and an outer circumference and which form a hole and the plurality of elongate members radiate outward from the outer circumference of the center frame portion , wherein the face portion has a surface without protrusions outward therefrom relative to the proximal end, wherein the center frame portion and the plurality of elongate members are arranged within a first plane substantially orthogonal to the longitudinal axis, and the self-expanding frame is formed from a cut-tube and said device being characterized in that the center frame portion is flattened from the cut-tube. a self-expanding frame having a proximal end , a distal end , and a longitudinal axis, the self-expanding frame including: a face portion having a pre-loaded flat configuration and (i) a center frame portion arranged at the proximal end and (ii) a plurality of elongate members extending from the center frame portion , the self-expanding frame lacking any eyelet that extends beyond the face portion , and a body portion ; and a face portion having a pre-loaded flat configuration and (i) a center frame portion arranged at the proximal end and (ii) a plurality of elongate members extending from the center frame portion , the self-expanding frame lacking any eyelet that extends beyond the face portion , and a body portion ; and a membrane attached to the self-expanding frame ; wherein the plurality of elongate members are configured to bend or flex in a plane orthogonal to the longitudinal axis and mitigate longitudinal movement of the face portion in response to a compressive force applied to the body portion of the self-expanding frame , wherein the center frame portion is formed by a plurality of arcs defining an inner and an outer circumference and which form a hole and the plurality of elongate members radiate outward from the outer circumference of the center frame portion , wherein the face portion has a surface without protrusions outward therefrom relative to the proximal end, wherein the center frame portion and the plurality of elongate members are arranged within a first plane substantially orthogonal to the longitudinal axis, and the self-expanding frame is formed from a cut-tube and said device being characterized in that the center frame portion is flattened from the cut-tube. <EOS>