A substrate coated with a multi-layer coating system comprising: a) optionally a primer layer applied to the substrate and deposited from a primer coating composition; b) a tie-coat layer applied to the substrate or to the optional primer layer, deposited from a tie-coat composition comprising a binder polymer obtainable by copolymerizing a mixture of ethylenically unsaturated monomers, the binder polymer comprising curable alkoxysilyl functional groups; and c) a topcoat layer applied to the tie-coat layer, the topcoat layer deposited from a non-aqueous liquid foul release coating composition comprising a curable resin system comprising i) a curable polymer having a backbone selected from a polyurethane, a polyether, a polyester, a polycarbonate or a hybrid of two or more thereof, and having at least one terminal or pendant alkoxysilyl group of formula -(C m H 2m )-Si(R 1 ) (3-n) (OR 2 ) n (I) wherein: n is 1, 2 or 3, preferably 2 or 3; each of R 1 and R 2 is, independently, an alkyl radical having 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms; m is an integer with a value in the range of from 1 to 20, and, optionally ii) a curing agent and/or a catalyst, wherein the non-aqueous liquid foul release coating composition is essentially free of a curable polysiloxane. a) optionally a primer layer applied to the substrate and deposited from a primer coating composition; b) a tie-coat layer applied to the substrate or to the optional primer layer, deposited from a tie-coat composition comprising a binder polymer obtainable by copolymerizing a mixture of ethylenically unsaturated monomers, the binder polymer comprising curable alkoxysilyl functional groups; and c) a topcoat layer applied to the tie-coat layer, the topcoat layer deposited from a non-aqueous liquid foul release coating composition comprising a curable resin system comprising i) a curable polymer having a backbone selected from a polyurethane, a polyether, a polyester, a polycarbonate or a hybrid of two or more thereof, and having at least one terminal or pendant alkoxysilyl group of formula -(C m H 2m )-Si(R 1 ) (3-n) (OR 2 ) n (I) wherein: n is 1, 2 or 3, preferably 2 or 3; each of R 1 and R 2 is, independently, an alkyl radical having 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms; m is an integer with a value in the range of from 1 to 20, and, optionally ii) a curing agent and/or a catalyst, wherein the non-aqueous liquid foul release coating composition is essentially free of a curable polysiloxane. i) a curable polymer having a backbone selected from a polyurethane, a polyether, a polyester, a polycarbonate or a hybrid of two or more thereof, and having at least one terminal or pendant alkoxysilyl group of formula -(C m H 2m )-Si(R 1 ) (3-n) (OR 2 ) n (I) wherein: n is 1, 2 or 3, preferably 2 or 3; each of R 1 and R 2 is, independently, an alkyl radical having 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms; m is an integer with a value in the range of from 1 to 20, and, optionally n is 1, 2 or 3, preferably 2 or 3; each of R 1 and R 2 is, independently, an alkyl radical having 1 to 6 carbon atoms, preferably 1 to 4 carbon atoms; m is an integer with a value in the range of from 1 to 20, and, optionally ii) a curing agent and/or a catalyst, <EOS>