mhurhangee/patent-ind-claim-en huggingface dataset:
A method for manufacturing a high strength aluminum alloy extruded material, the aluminum alloy extruded material comprising, by mass: 6.0 to 8.0% of Zn, 1.50 to 2.70% of Mg, 0.20 to 1.50% of Cu, 0.005 to 0.05% of Ti, and 0.10 to 0.25% of Zr, 0.3% or less of Mn, 0.05% or less of Cr, 0.25% or less of Sr, and 0.10 to 0.50% in total among Zr, Mn, Cr and Sr, with the balance being Al and unavoidable impurities including 0.2% or less Fe and 0. 1% or less Si, characterized in that a columnar billet casted at a casting rate of 50 mm/min or more and having an average crystalized grain diameter of 250 μm or less is subjected to homogenization treatment at a temperature of 470 to 530°C for two to 24 hours, the homogenized billet is then pre-heated to a temperature of 400 to 480°C to obtain a cast billet, the resulting cast billet is subjected to extrusion processing, fan air cooling the extruded material at an average cooling rate of 100 to 450°C/min immediately after the extrusion processing, and the extruded material is then subjected to artificial aging treatment, and the artificial aging treatment comprises a first-stage aging at a temperature of 90 to 120°C for one to 24 hours, and a subsequent second-stage aging at a temperature of 130 to 180°C for one to 24 hours. 6.0 to 8.0% of Zn, 1.50 to 2.70% of Mg, 0.20 to 1.50% of Cu, 0.005 to 0.05% of Ti, and 0.10 to 0.25% of Zr, 0.3% or less of Mn, 0.05% or less of Cr, 0.25% or less of Sr, and 0.10 to 0.50% in total among Zr, Mn, Cr and Sr, with the balance being Al and unavoidable impurities including 0.2% or less Fe and 0. 1% or less Si, characterized in that a columnar billet casted at a casting rate of 50 mm/min or more and having an average crystalized grain diameter of 250 μm or less is subjected to homogenization treatment at a temperature of 470 to 530°C for two to 24 hours, the homogenized billet is then pre-heated to a temperature of 400 to 480°C to obtain a cast billet, the resulting cast billet is subjected to extrusion processing, fan air cooling the extruded material at an average cooling rate of 100 to 450°C/min immediately after the extrusion processing, and the extruded material is then subjected to artificial aging treatment, and the artificial aging treatment comprises a first-stage aging at a temperature of 90 to 120°C for one to 24 hours, and a subsequent second-stage aging at a temperature of 130 to 180°C for one to 24 hours.
An agricultural distributor for distributing liquid active agents , preferably crop protection means and/or fertilizers, comprising a carrier vehicle having at least two running wheels ; and a spray boom arranged indirectly or directly on the carrier vehicle , and on which a plurality of spaced-apart nozzle carriers are arranged, which are designed for receiving at least one spray nozzle each for distributing the active agent to be distributed; a control device which is designed to activate the spray nozzles held in the nozzle carriers ; characterized in that the plurality of nozzle carriers comprise a plurality of first nozzle carriers in which at least one asymmetrically operating spray nozzle is in each case held, wherein the first nozzle carriers are arranged in regions of the spray boom that - as seen in the direction of travel (F) of the distributor - are arranged laterally adjacent to a travel lane provided for the running wheels of the carrier vehicle .
A disposable absorbent hygiene product comprising a main part having a body facing surface intended to face the body of a user and a garment facing surface intended to face away from the body of a user, the main part comprising a liquid permeable topsheet at the body facing surface, a liquid impermeable backsheet at the garment facing surface, and an absorbent assembly arranged between the topsheet and the backsheet, main part having a having a front end and a back end , and defining a longitudinal direction (L) from said front end towards said back end and defining a transversal direction (T) perpendicular to the longitudinal direction, wherein the absorbent assembly is divided by two, imaginary, transversally extending lines (T1, T2) into a front region (Rf) towards said front end, having a longitudinal length of from 10 to 40% of the absorbent assembly longitudinal length; a back region (Rb) towards said back end, having a longitudinal length of from 10 to 40% of the absorbent assembly longitudinal length; and a central region (Rc) between said front region and said back region, the front, back, and central regions being non-overlapping; wherein in the front and back regions, the absorbent assembly comprises cellulosic fibers optionally mixed with super absorbent polymers, with a super absorbent polymer concentration of from 0 to 30 weight%, based on the total weight of cellulosic fibers and super absorbent polymer, and a cellulosic fiber basis weight of from 50 to 200 g/m 2 ; wherein said absorbent assembly comprises a first absorbent core comprising cellulosic fibers, optionally mixed with super absorbent polymers, with a super absorbent polymer concentration of from 0 to 30 wt%, and having a cellulosic fiber basis weight of from 50 to 200 g/m 2 , said first core extending over the full longitudinal length of the absorbent assembly, and a second absorbent core positioned in said central region and in stacked relationship with said first absorbent core; and wherein said central region provides from 70% to 100% of the total retention capacity of the absorbent assembly as measured according to NWSP 241.0R2 , wherein the liquid permeable topsheet material comprises a hydrophilically treated polypropylene spunbond nonwoven or spunbond/meltblown composite nonwoven, having a basis weight of from 8 to 20 g/m 2 ; and wherein an acquisition layer material is provided sandwiched between said topsheet and said absorbent assembly, being a through air bonded nonwoven having a basis weight of from 40 to 60 g/m 2 and a caliper of at least 0.9 mm as measured according the method NWSP 120.6, option A, at 0.5 kPa pressure.
A method for three-dimensionally printing an article comprising the steps of: (a) forming a layer of a build material powder , the build material powder having a first mean particle size diameter; (b) selectively printing by jet deposition on the layer a binder fluid , the binder fluid comprising a particulate matter having a second mean particle size diameter which is one-seventh or less of the first mean particle size diameter and greater than 1 micron; and (c) repeating steps (a) and (b) until the article is formed. (a) forming a layer of a build material powder , the build material powder having a first mean particle size diameter; (b) selectively printing by jet deposition on the layer a binder fluid , the binder fluid comprising a particulate matter having a second mean particle size diameter which is one-seventh or less of the first mean particle size diameter and greater than 1 micron; and (c) repeating steps (a) and (b) until the article is formed.
A process for purifying virus-like particles (VLPs) comprising Enterobacteria phage MS2 capsid protein defined by SEQ ID NO:3, and enclosing at least one heterologous cargo molecule, the process comprising: (a) obtaining a cell lysate comprising a plurality of the VLPs; (b) contacting the cell lysate with a protease for a time and under a condition sufficient to hydrolyze cell lysis products other than the VLPs to form a hydrolysate; and (c) isolating the VLPs from the hydrolysate.
An applicator for attaching a body attachable unit to a human body, the applicator comprising: a main case having an inner space and an open side, wherein a pressure button is installed at one side of the main case ; a plunger body disposed in a first location inside the main case , wherein the plunger body is configured to be movable outwardly to a second location and is configured to be decoupled from the first location by the operation of the pressure button ; and a spring (S1) configured to apply an elastic force to the plunger body so that the plunger body can move from the first location and the second location; a body attachable unit configured to be attachable to a human body for blood glucose measurement, the body attachable unit being coupled to the plunger body so as to be movable from the first location to the second location together with the plunger body , wherein the pressure button is installed to be mode-changeable between a first mode, in which pressurizing movement by pressurizing manipulation is prevented, and a second mode, in which the pressurizing movement by the pressurizing manipulation is allowed, wherein the pressure button comprises a locking unit configured to block a mode change of the pressure button from the first mode to the second mode and to release blocking of the mode change, and wherein the pressure button is configured to be mode-changed from the first mode to the second mode by being slidably moved along an outer surface of the main case , and the locking unit is configured to block the mode change of the pressure button by limiting sliding movement of the pressure button . a main case having an inner space and an open side, wherein a pressure button is installed at one side of the main case ; a plunger body disposed in a first location inside the main case , wherein the plunger body is configured to be movable outwardly to a second location and is configured to be decoupled from the first location by the operation of the pressure button ; and a spring (S1) configured to apply an elastic force to the plunger body so that the plunger body can move from the first location and the second location; a body attachable unit configured to be attachable to a human body for blood glucose measurement, the body attachable unit being coupled to the plunger body so as to be movable from the first location to the second location together with the plunger body , wherein the pressure button is installed to be mode-changeable between a first mode, in which pressurizing movement by pressurizing manipulation is prevented, and a second mode, in which the pressurizing movement by the pressurizing manipulation is allowed, wherein the pressure button comprises a locking unit configured to block a mode change of the pressure button from the first mode to the second mode and to release blocking of the mode change, and wherein the pressure button is configured to be mode-changed from the first mode to the second mode by being slidably moved along an outer surface of the main case , and the locking unit is configured to block the mode change of the pressure button by limiting sliding movement of the pressure button .
A method of processing a long product on a numerical control machine including a machine bed and a gantry holding through a bevel head drive box a cutting torch extending along a torch center , the method comprising the steps of: moving the gantry along a substantial length of the long product and machine bed in the lengthwise direction while performing a step of cutting the long product with the cutting torch to process the long product, and moving the bevel head drive box, wherein the torch center is capable of moving in the directions of at least the X-axis , Y-axis and Z-axis, the method further comprising the step of controlling the torch center orientation, wherein the torch center is capable of rotating about a twist-axis extending along the X-axis, and about a tilt-axis extending along a Y-axis relative to an arbitrary coordinate system defining the dimensions of the long product, characterized in that the cutting torch is extended from a focal point , defined at the intersection of the torch center and the twist-axis, to a new torch tip point in order for the cutting torch to be able, while cutting horizontally, to cut long product flanges with respectively a clearance between the bevel head drive box and the long product flange being processed. moving the gantry along a substantial length of the long product and machine bed in the lengthwise direction while performing a step of cutting the long product with the cutting torch to process the long product, and moving the bevel head drive box, wherein the torch center is capable of moving in the directions of at least the X-axis , Y-axis and Z-axis, the method further comprising the step of controlling the torch center orientation, wherein the torch center is capable of rotating about a twist-axis extending along the X-axis, and about a tilt-axis extending along a Y-axis relative to an arbitrary coordinate system defining the dimensions of the long product, characterized in that the cutting torch is extended from a focal point , defined at the intersection of the torch center and the twist-axis, to a new torch tip point in order for the cutting torch to be able, while cutting horizontally, to cut long product flanges with respectively a clearance between the bevel head drive box and the long product flange being processed.
A pharmaceutical composition comprising an effective amount of plasminogen for use in preventing, treating and/or eliminating diabetic nephropathy in a subject, comprising administering an effective amount of plasminogen to the subject, wherein the amino acid sequence of plasminogen is as shown in SEQ ID No.2, or wherein the plasminogen has at least 90%, 95%, 96%, 97%, 98% or 99% sequence identity with SEQ ID No. 2, or at least 95%, 96%, 97%, 98% or 99% sequence identity with SEQ ID No. 6, 8, 10 or 12, and still has the activity of plasminogen. wherein the amino acid sequence of plasminogen is as shown in SEQ ID No.2, or wherein the plasminogen has at least 90%, 95%, 96%, 97%, 98% or 99% sequence identity with SEQ ID No. 2, or at least 95%, 96%, 97%, 98% or 99% sequence identity with SEQ ID No. 6, 8, 10 or 12, and still has the activity of plasminogen.
Bearing system , in particular for supporting a motor vehicle assembly on a motor vehicle body, said system comprising a fluid working chamber , which is fluidically connected by means of at least one fluid channel to a fluid compensation chamber provided in a housing of the bearing system , the fluid working chamber and the fluid compensation chamber being separated by a divider , in which the at least one fluid channel lies, wherein the divider is decoupled from the housing by means of an elastic element engaging around the periphery of the divider , wherein the housing has a cover , which accommodates the fluid compensation chamber , and a supporting part , which holds a flexible member of the bearing system, characterised in that the cover engages between the supporting part and the elastic element , such that the elastic element , the cover and the supporting part follow one another directly in sequence when viewed in radial direction with respect to a longitudinal centre axis of the bearing system , and that an elastic membrane , which separates a fluid damping chamber rheologically from the fluid working chamber , is fastened on the divider , wherein the fluid damping chamber is fluidically connected by way of a throttle channel with an outer surrounding of the bearing system , wherein the fluid damping chamber is arranged in the divider and the throttle channel is formed in a protrusion of the cover encompassed annularly at least in some regions by the fluid compensation chamber , said protrusion protruding towards the divider .
A T cell comprising a chimeric intracellular signaling molecule, wherein the chimeric intracellular signaling molecule comprises: a) an intracellular domain of a co-stimulatory molecule, and b) a detectable tag or a hinge/transmembrane domain, wherein the chimeric intracellular signaling molecule substantially lacks an extracellular ligand-binding domain, wherein the intracellular domain of the chimeric intracellular signaling molecule comprises at least one signaling domain selected from the group consisting of CD3 signaling domain, CD27 signaling domain, CD28 signaling domain, ICOS signaling domain, 4-1BB signaling domain, T cell receptor (TCR) signaling domain, and any combination thereof, wherein the T cell expresses the chimeric intracellular signaling molecule, wherein expression of the chimeric intracellular signaling molecule metabolically enhances the T cell and improves cytotoxicity and resistance to immunosuppression when in a tumor microenvironment, and wherein the T cell further comprises a bispecific antibody, wherein the bispecific antibody comprises a first antigen binding domain that binds to a first antigen and a second antigen binding domain that binds to a second antigen, and wherein the first antigen binding domain binds to a target cell and the second antigen binding domain binds to an activated T cell. a) an intracellular domain of a co-stimulatory molecule, and b) a detectable tag or a hinge/transmembrane domain, wherein the intracellular domain of the chimeric intracellular signaling molecule comprises at least one signaling domain selected from the group consisting of CD3 signaling domain, CD27 signaling domain, CD28 signaling domain, ICOS signaling domain, 4-1BB signaling domain, T cell receptor (TCR) signaling domain, and any combination thereof, wherein the T cell expresses the chimeric intracellular signaling molecule, wherein expression of the chimeric intracellular signaling molecule metabolically enhances the T cell and improves cytotoxicity and resistance to immunosuppression when in a tumor microenvironment, and wherein the T cell further comprises a bispecific antibody, wherein the bispecific antibody comprises a first antigen binding domain that binds to a first antigen and a second antigen binding domain that binds to a second antigen, and wherein the first antigen binding domain binds to a target cell and the second antigen binding domain binds to an activated T cell.
Dalcetrapib for use in the treatment or the prevention of a cardiovascular disorder in a subject, wherein the subject is known to carry an improved response genotype rs11647778/CC or rs11647778/CG and optionally an improved response genotype at one or more of the following sites: rs1967309, rs12595857, rs2239310, rs11647828, rs8049452, rs12935810, rs74702385, rsl7136707, rs8061182, rs111590482, rs4786454, rs2283497, rs2531967, rs3730119, rs13337675, rs12920508, rs12599911, rs2531971 and rs2238448.
A network authentication method, comprising: obtaining (S301), by a network device, an identity of a terminal device; generating (S302), by the network device, a symmetric key on the network device side based on the identity of the terminal device and a first key of the network device; generating (S303), by the network device, a first sequence number for the terminal device; determining (S304), by the network device, a correct sequence number of the terminal device based on the first sequence number; generating (S305), by the network device, a first authentication token based on the symmetric key on the network device side, the correct sequence number, a first random number, and an authentication management field parameter configured by the network device for the terminal device, wherein the authentication management field parameter is used to limit parameters involved in the network authentication process of the terminal device; sending (S306), by the network device, the first random number and the first authentication token to the terminal device; receiving (S309), by the network device, an authentication response message sent by the terminal device, wherein the authentication response message comprises a first authentication parameter; generating (S310), by the network device, a second authentication parameter based on the symmetric key on the network device side and the first random number; and authenticating (S311), by the network device, the terminal device based on the first authentication parameter and the second authentication parameter. obtaining (S301), by a network device, an identity of a terminal device; generating (S302), by the network device, a symmetric key on the network device side based on the identity of the terminal device and a first key of the network device; generating (S303), by the network device, a first sequence number for the terminal device; determining (S304), by the network device, a correct sequence number of the terminal device based on the first sequence number; generating (S305), by the network device, a first authentication token based on the symmetric key on the network device side, the correct sequence number, a first random number, and an authentication management field parameter configured by the network device for the terminal device, wherein the authentication management field parameter is used to limit parameters involved in the network authentication process of the terminal device; sending (S306), by the network device, the first random number and the first authentication token to the terminal device; receiving (S309), by the network device, an authentication response message sent by the terminal device, wherein the authentication response message comprises a first authentication parameter; generating (S310), by the network device, a second authentication parameter based on the symmetric key on the network device side and the first random number; and authenticating (S311), by the network device, the terminal device based on the first authentication parameter and the second authentication parameter.
A hydraulic system for a construction machinery, comprising: a hydraulic pump ; a cylinder control valve adapted to control the flow of hydraulic fluid from the hydraulic pump to a hydraulic cylinder ; an operating device adapted to operate the cylinder control valve ; a regeneration motor adapted to be driven by return fluid from one hydraulic fluid port of the hydraulic cylinder ; a regeneration electric motor adapted to convert rotary power of the regeneration motor into electric energy; and a pilot hydraulic pressure source ; the hydraulic system characterized by comprising: at least one return fluid control valve adapted to control the flow of the return fluid according to pilot pressure that is led from the pilot hydraulic pressure source in conjunction with an operation on the operating device ; at least one solenoid valve for return fluid control valve adapted to control the pilot pressure for driving the return fluid control valve ; and a malfunction prevention device adapted to be capable of interrupting the delivery of the pilot pressure from the solenoid valve for return fluid control valve to the return fluid control valve . a hydraulic pump ; a cylinder control valve adapted to control the flow of hydraulic fluid from the hydraulic pump to a hydraulic cylinder ; an operating device adapted to operate the cylinder control valve ; a regeneration motor adapted to be driven by return fluid from one hydraulic fluid port of the hydraulic cylinder ; a regeneration electric motor adapted to convert rotary power of the regeneration motor into electric energy; and a pilot hydraulic pressure source ; the hydraulic system characterized by comprising: at least one return fluid control valve adapted to control the flow of the return fluid according to pilot pressure that is led from the pilot hydraulic pressure source in conjunction with an operation on the operating device ; at least one solenoid valve for return fluid control valve adapted to control the pilot pressure for driving the return fluid control valve ; and a malfunction prevention device adapted to be capable of interrupting the delivery of the pilot pressure from the solenoid valve for return fluid control valve to the return fluid control valve . at least one return fluid control valve adapted to control the flow of the return fluid according to pilot pressure that is led from the pilot hydraulic pressure source in conjunction with an operation on the operating device ; at least one solenoid valve for return fluid control valve adapted to control the pilot pressure for driving the return fluid control valve ; and a malfunction prevention device adapted to be capable of interrupting the delivery of the pilot pressure from the solenoid valve for return fluid control valve to the return fluid control valve .