mhurhangee/patent-ind-claim-en huggingface dataset:
Composition comprising, in a cosmetically acceptable medium, at least one continuous oil phase, characterized in that the oil phase comprises a) at least one non-volatile non-cyclic silicone oil with a viscosity at 25°C ranging from 4 to 5000 mm 2 /s, better still from 4 to 1000 mm 2 /s and even better still from 4 to 200 mm 2 /s and corresponding to formula (II) below: x being an integer ranging from 1 to 50, better still from 1 to 20 and more specifically from 1 to 10 ; and b) at least one lipophilic organic UV-screening agent; and c) hydrophobic silica aerogel particles with a specific surface area per unit of mass (SM) ranging from 200 to 1500 m 2 /g, preferably from 600 to 1200 m 2 /g and better still from 600 to 800 m 2 /g, and a size, expressed as the volume mean diameter (D[0.5]), of less than 1500 μm, preferably ranging from 1 to 30 μm, more preferentially from 5 to 25 μm, better still from 5 to 20 μm and even better still from 5 to 15 μm. a) at least one non-volatile non-cyclic silicone oil with a viscosity at 25°C ranging from 4 to 5000 mm 2 /s, better still from 4 to 1000 mm 2 /s and even better still from 4 to 200 mm 2 /s and corresponding to formula (II) below: x being an integer ranging from 1 to 50, better still from 1 to 20 and more specifically from 1 to 10 ; and b) at least one lipophilic organic UV-screening agent; and c) hydrophobic silica aerogel particles with a specific surface area per unit of mass (SM) ranging from 200 to 1500 m 2 /g, preferably from 600 to 1200 m 2 /g and better still from 600 to 800 m 2 /g, and a size, expressed as the volume mean diameter (D[0.5]), of less than 1500 μm, preferably ranging from 1 to 30 μm, more preferentially from 5 to 25 μm, better still from 5 to 20 μm and even better still from 5 to 15 μm.
A compound of the formula I where: Ar 1 is phenyl and is substituted with 0-3 substituents selected from cyano, halo, alkyl, haloalkyl, and haloalkoxy; Ar 2 -OR is selected from R is hydrogen or a prodrug moiety selected from the group consisting of amino acid esters, phosphonic acids, alkoxyphosphononate acid, alkyl carabamates, amino acid carbamates, alkyl phosporamidates, aryl phosphoramidates, and sulfamates; X is a bond or C 1 -C 3 alkylene; n is 1 or 2; ring A is piperazinyl, homopiperazinyl, or 2,5-diazabicyclo[2.2.1]heptanes, piperazin-2-one and is substituted with 0-4 substituents selected from halo, alkyl, hydroxy, or alkoxy; or a pharmaceutically acceptable salt thereof. Ar 1 is phenyl and is substituted with 0-3 substituents selected from cyano, halo, alkyl, haloalkyl, and haloalkoxy; Ar 2 -OR is selected from R is hydrogen or a prodrug moiety selected from the group consisting of amino acid esters, phosphonic acids, alkoxyphosphononate acid, alkyl carabamates, amino acid carbamates, alkyl phosporamidates, aryl phosphoramidates, and sulfamates; X is a bond or C 1 -C 3 alkylene; n is 1 or 2; ring A is piperazinyl, homopiperazinyl, or 2,5-diazabicyclo[2.2.1]heptanes, piperazin-2-one and is substituted with 0-4 substituents selected from halo, alkyl, hydroxy, or alkoxy;
A component for an ultrasonic surgical instrument, the component comprising: a connector module for providing a rotatable electrical connection between a first conductor and a first link rotatable relative to the first conductor, the connector module structured to receive an ultrasonic hand piece, wherein the ultrasonic hand piece is configured to acoustically couple to a waveguide that extends along a longitudinal axis when received by the connector module, and wherein the connector module comprises: a first conductor extending at least partially around the longitudinal axis and defining a conductive path; and a first link rotatable about the longitudinal axis relative to the first conductor between a first position and a second position that is different from the first position, wherein the first link is configured to rotationally couple with the ultrasonic hand piece, and wherein the first link comprises: a first contact positioned to electrically contact the first conductor along the conductive path when the first link is in each of the first position and the second position; and a second contact electrically coupled to the first contact, wherein the second contact is configured to electrically contact the ultrasonic hand piece when the first link is in each of the first position and the second position. a first conductor extending at least partially around the longitudinal axis and defining a conductive path; and a first link rotatable about the longitudinal axis relative to the first conductor between a first position and a second position that is different from the first position, wherein the first link is configured to rotationally couple with the ultrasonic hand piece, and wherein the first link comprises: a first contact positioned to electrically contact the first conductor along the conductive path when the first link is in each of the first position and the second position; and a second contact electrically coupled to the first contact, wherein the second contact is configured to electrically contact the ultrasonic hand piece when the first link is in each of the first position and the second position. a first contact positioned to electrically contact the first conductor along the conductive path when the first link is in each of the first position and the second position; and a second contact electrically coupled to the first contact, wherein the second contact is configured to electrically contact the ultrasonic hand piece when the first link is in each of the first position and the second position.
Medical product , preferably for use in treating, in particular filling and/or closing a bone cavity, wherein the product comprises a plurality of interconnected members , wherein each member has a peripheral boundary and the boundaries of adjacent members interlock, wherein the product comprises a three-dimensional structure composed of the members , wherein the three-dimensional structure has a multilayer construction, wherein each layer has interconnected members , wherein the boundaries of members engage with adjacent layers, characterized in that a part of the members are interconnected such that they are not moveable relative to one another, wherein the members have a single-part or monolithic configuration and are produced by means of an additive or generative production method.
A composition comprising: HFO-1234ze and optionally HFO-1234yf; HFC-134a and optionally HFC-134; and HCFC-1122, HCFC-124, CFC-1113, and 3,3,3-trifluoropropyne. HFO-1234ze and optionally HFO-1234yf; HFC-134a and optionally HFC-134; and HCFC-1122, HCFC-124, CFC-1113, and 3,3,3-trifluoropropyne.
A variant PD-L1 polypeptide, comprising an IgV domain or both an IgV domain and an IgC domain, wherein the variant PD-L1 polypeptide comprises an amino acid substitution in an unmodified human PD-L1 corresponding to amino acid substitution N45D with reference to the numbering of SEQ ID NO:30, wherein the variant PD-L1 polypeptide specifically binds to the ectodomain of PD-1 with increased affinity compared to the binding of the unmodified human PD-L1 to the ectodomain of PD-1; wherein the unmodified PD-L1 comprises the sequence of amino acids set forth in SEQ ID NO:30 or a portion thereof comprising the IgV domain or the IgV domain and IgC domain; and wherein the variant PD-L1 polypeptide comprises a sequence of amino acids that exhibits at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% sequence identity to SEQ ID NO:30, 55, 309 or 1728. wherein the unmodified PD-L1 comprises the sequence of amino acids set forth in SEQ ID NO:30 or a portion thereof comprising the IgV domain or the IgV domain and IgC domain; and wherein the variant PD-L1 polypeptide comprises a sequence of amino acids that exhibits at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% or 99% sequence identity to SEQ ID NO:30, 55, 309 or 1728.
Functional chip (PFL) comprising: - a substrate (P2) comprising a first face and a second face (S2), the second face of the substrate (P2) forming the front face (S2) of the functional chip; - a first oxide layer (OXC) on the first face of the substrate (P2); - a second oxide layer (BOX) on the first oxide layer (OXC); - a first routing level (NM1) formed on the surface of the second oxide layer (BOX) in contact with the first oxide layer (OXC); - a third oxide layer (OX) on the second oxide layer (BOX) wherein at least one semiconductor component (QB) is inserted; - a rear face (S1) formed by the surface of the third oxide layer opposite the second oxide layer (BOX), the rear face (S1) comprising a plurality of superconductor routing tracks (NS) surrounded at least partially by one or more conductor routing tracks (NM2), the semiconductor component (QB) being connected to the superconductor routing tracks (NS) via superconductor vias (VQS) and the conductor routing tracks (NM2) of the rear face (S1) being connected to the first routing level (NM1) via conductor vias (V12). - a substrate (P2) comprising a first face and a second face (S2), the second face of the substrate (P2) forming the front face (S2) of the functional chip; - a first oxide layer (OXC) on the first face of the substrate (P2); - a second oxide layer (BOX) on the first oxide layer (OXC); - a first routing level (NM1) formed on the surface of the second oxide layer (BOX) in contact with the first oxide layer (OXC); - a third oxide layer (OX) on the second oxide layer (BOX) wherein at least one semiconductor component (QB) is inserted; - a rear face (S1) formed by the surface of the third oxide layer opposite the second oxide layer (BOX), the rear face (S1) comprising a plurality of superconductor routing tracks (NS) surrounded at least partially by one or more conductor routing tracks (NM2), the semiconductor component (QB) being connected to the superconductor routing tracks (NS) via superconductor vias (VQS) and the conductor routing tracks (NM2) of the rear face (S1) being connected to the first routing level (NM1) via conductor vias (V12).
A computer system for generating positional information about a stent in a lumen of a vessel, the computer system comprising: an electronic memory device and an electronic processor in communication with the electronic memory device, wherein the memory device comprises instructions that when executed by the processor cause the processor to: generate an optical coherence image data set in response to an OCT scan of a sample containing at least one stent, with an optical coherence image comprising a collection of scan lines acquired one scan line at a time as an OCT catheter rotates; determine a lumen boundary from the optical coherence image data set; identify one or more stent struts of the stent by detecting a one-dimensional local cue in one or more scan lines of the optical coherence image data set; measure a distance from one or more stent struts to an edge of the lumen boundary; calculate stent malapposition in response to the measured distance; and display calculated stent malapposition. an electronic memory device and an electronic processor in communication with the electronic memory device, wherein the memory device comprises instructions that when executed by the processor cause the processor to: generate an optical coherence image data set in response to an OCT scan of a sample containing at least one stent, with an optical coherence image comprising a collection of scan lines acquired one scan line at a time as an OCT catheter rotates; determine a lumen boundary from the optical coherence image data set; identify one or more stent struts of the stent by detecting a one-dimensional local cue in one or more scan lines of the optical coherence image data set; measure a distance from one or more stent struts to an edge of the lumen boundary; calculate stent malapposition in response to the measured distance; and display calculated stent malapposition. generate an optical coherence image data set in response to an OCT scan of a sample containing at least one stent, with an optical coherence image comprising a collection of scan lines acquired one scan line at a time as an OCT catheter rotates; determine a lumen boundary from the optical coherence image data set; identify one or more stent struts of the stent by detecting a one-dimensional local cue in one or more scan lines of the optical coherence image data set; measure a distance from one or more stent struts to an edge of the lumen boundary; calculate stent malapposition in response to the measured distance; and display calculated stent malapposition.
Method for manufacturing an integrated circuit (CI) capable of protecting data stored in a memory of the integrated circuit, comprising: - a manufacture of the memory (MEM) including a manufacture of at least one state transistor (TE) comprising a floating gate (FG), and a writing of a respective data in each state transistor (TE) comprising a storage of a charge representing the data in the floating gate (FG) of the state transistor (TE); - a manufacture of a protection device (DIS) comprising a production, for at least one state transistor (TE), of at least one capacitive structure (SC) comprising: -- a first electrically conductive body (CC1) coupled to the floating gate of the state transistor (FG), -- a dielectric body (IMD), and -- a second electrically conductive body (CC2) coupled to a ground terminal (GND), wherein the dielectric body (IMD) is configured: --- to electrically couple the floating gate (FG) and the ground terminal (GND) so as to modify the charge of the floating gate (FG) and to lose the corresponding data if an aqueous solution is put in contact with the dielectric body, and --- to electrically isolate the floating gate (FG) and the ground terminal (GND) otherwise. - a manufacture of the memory (MEM) including a manufacture of at least one state transistor (TE) comprising a floating gate (FG), and a writing of a respective data in each state transistor (TE) comprising a storage of a charge representing the data in the floating gate (FG) of the state transistor (TE); - a manufacture of a protection device (DIS) comprising a production, for at least one state transistor (TE), of at least one capacitive structure (SC) comprising: -- a first electrically conductive body (CC1) coupled to the floating gate of the state transistor (FG), -- a dielectric body (IMD), and -- a second electrically conductive body (CC2) coupled to a ground terminal (GND), wherein the dielectric body (IMD) is configured: --- to electrically couple the floating gate (FG) and the ground terminal (GND) so as to modify the charge of the floating gate (FG) and to lose the corresponding data if an aqueous solution is put in contact with the dielectric body, and --- to electrically isolate the floating gate (FG) and the ground terminal (GND) otherwise. -- a first electrically conductive body (CC1) coupled to the floating gate of the state transistor (FG), -- a dielectric body (IMD), and -- a second electrically conductive body (CC2) coupled to a ground terminal (GND), --- to electrically couple the floating gate (FG) and the ground terminal (GND) so as to modify the charge of the floating gate (FG) and to lose the corresponding data if an aqueous solution is put in contact with the dielectric body, and --- to electrically isolate the floating gate (FG) and the ground terminal (GND) otherwise.
A label having a lengthwise direction and a transverse direction, the label comprising: a back sheet having adhesive on its rear surface; a leaflet having a front sheet which extends from a first transverse edge to a second transverse edge spaced from said first transverse edge in said lengthwise direction, the leaflet being secured with respect to the front surface of the back sheet ; a laminate layer having an adhesive on its rear surface secured to and covering the front sheet, the laminate layer having an extended part projecting beyond the front sheet in the lengthwise direction away from said second transverse edge to a free edge , characterised by that the extended part of the laminate layer having a transverse line of weakening which is adjacent but spaced from said second transverse edge and which is spaced from the free edge of the laminate layer by a lengthwise distance at least the length between the first and second transverse edges . a back sheet having adhesive on its rear surface; a leaflet having a front sheet which extends from a first transverse edge to a second transverse edge spaced from said first transverse edge in said lengthwise direction, the leaflet being secured with respect to the front surface of the back sheet ; a laminate layer having an adhesive on its rear surface secured to and covering the front sheet, the laminate layer having an extended part projecting beyond the front sheet in the lengthwise direction away from said second transverse edge to a free edge , characterised by that the extended part of the laminate layer having a transverse line of weakening which is adjacent but spaced from said second transverse edge and which is spaced from the free edge of the laminate layer by a lengthwise distance at least the length between the first and second transverse edges .
A medical infusion fluid handling system, comprising: a carriage arranged to receive a plurality of solution lines each having a connector end and a cap , the carriage being arranged to move along a first direction so as to move the connector ends of the solution lines along the first direction; a cap stripper arranged to engage with caps on the solution lines on the carriage, to move in a second direction transverse to the first direction, and to move with the carriage along the first direction; and a housing that encloses components of the system and a door that is movably mounted to the housing; the cap stripper being arranged to move in the second direction to engage with caps on the solution lines on the carriage, and the carriage being mounted to the door. a carriage arranged to receive a plurality of solution lines each having a connector end and a cap , the carriage being arranged to move along a first direction so as to move the connector ends of the solution lines along the first direction; a cap stripper arranged to engage with caps on the solution lines on the carriage, to move in a second direction transverse to the first direction, and to move with the carriage along the first direction; and a housing that encloses components of the system and a door that is movably mounted to the housing; the cap stripper being arranged to move in the second direction to engage with caps on the solution lines on the carriage, and the carriage being mounted to the door.
A compound ABX196 of formula (I): or one of its pharmaceutically acceptable salts, for use in a method for the treatment of bladder cancer, wherein said method does not comprise the administration of a further chemotherapeutic agent and/or an immunotherapeutic agent and/or an antigen.
An M way cache memory, comprising: a plurality of ways, each way comprising an instruction memory portion, wherein the instruction memory portion comprises a plurality of instruction memory locations configured to store instruction data encoding a plurality of CPU instructions; a controller configured to determine that each of a predetermined number of cache memory hit conditions has occurred; and a replacement policy circuit configured to identify one of the plurality of ways as having experienced a fewest quantity of hits of the predetermined number of cache memory hit conditions, wherein the controller is further configured to determine that a cache memory miss condition has occurred, and, in response to the cache memory miss condition, to cause instruction data retrieved from a RAM memory to be written to the instruction memory portion of the way identified by the replacement policy circuit. a plurality of ways, each way comprising an instruction memory portion, wherein the instruction memory portion comprises a plurality of instruction memory locations configured to store instruction data encoding a plurality of CPU instructions; a controller configured to determine that each of a predetermined number of cache memory hit conditions has occurred; and a replacement policy circuit configured to identify one of the plurality of ways as having experienced a fewest quantity of hits of the predetermined number of cache memory hit conditions, wherein the controller is further configured to determine that a cache memory miss condition has occurred, and, in response to the cache memory miss condition, to cause instruction data retrieved from a RAM memory to be written to the instruction memory portion of the way identified by the replacement policy circuit.
A method of detecting trajectory information for a subsonic projectile, comprising: collecting detection signals from an array of detection microphones , the detection microphones being established in a non co-linear spatial relationship with respect to each other, determining from at least one of the detection signals the existence of an acoustic waveform, including a wake contribution, characteristic of the wake of a subsonic projectile passing on a trajectory nearby, and a muzzle blast waveform, characteristic of a muzzle blast; obtaining a plurality of time samples of the wake contribution over a time period; processing the plurality of time samples of the wake contribution and the detected muzzle blast waveform to determine geometric characteristics of the trajectory of the projectile. collecting detection signals from an array of detection microphones , the detection microphones being established in a non co-linear spatial relationship with respect to each other, determining from at least one of the detection signals the existence of an acoustic waveform, including a wake contribution, characteristic of the wake of a subsonic projectile passing on a trajectory nearby, and a muzzle blast waveform, characteristic of a muzzle blast; obtaining a plurality of time samples of the wake contribution over a time period; processing the plurality of time samples of the wake contribution and the detected muzzle blast waveform to determine geometric characteristics of the trajectory of the projectile.
Device for feeding a liquid odorant into a gas network, comprising a housing which is designed as a pipe section through which gas can flow, an odorant nozzle, an evaporation body, the odorant nozzle and the evaporation body being inserted in a sealed manner into the housing through an opening in the wall of the housing so that the evaporation body extends at least through a part of the free cross-section of the housing within the housing , the device being characterised in that it comprises a valve body which can be moved from a first, open position to a second, closed position, the valve body closing the cross-section of the housing through which gas can flow and opening the cross-section of the housing through which gas can flow in the second position, and wherein the valve body in the second position forms with the housing an extraction lock for the evaporation body and/or the odorant nozzle, wherein the housing comprises a first, second and third pipe outlet , wherein the valve body in the second closed position opens said third pipe outlet and wherein said third pipe outlet is preferably closed with an inspection lid .