mhurhangee/patent-ind-claim-en huggingface dataset:
An antibody molecule for use in treating systemic sclerosis, wherein the antibody molecule binds to and neutralizes human TGFβ1, TGFβ2 and TGFβ3, and wherein the antibody molecule comprises: (i) a heavy chain comprising a heavy chain variable (VH) domain, wherein the VH domain comprises the amino acid sequence of SEQ ID NO: 2, and a human IgG 4 constant region, and (ii) a light chain comprising a light chain variable (VL) domain, wherein the VL domain comprises the amino acid sequence of SEQ ID NO: 7. wherein the antibody molecule binds to and neutralizes human TGFβ1, TGFβ2 and TGFβ3, and wherein the antibody molecule comprises: (i) a heavy chain comprising a heavy chain variable (VH) domain, wherein the VH domain comprises the amino acid sequence of SEQ ID NO: 2, and a human IgG 4 constant region, and (ii) a light chain comprising a light chain variable (VL) domain, wherein the VL domain comprises the amino acid sequence of SEQ ID NO: 7. (i) a heavy chain comprising a heavy chain variable (VH) domain, wherein the VH domain comprises the amino acid sequence of SEQ ID NO: 2, and a human IgG 4 constant region, and (ii) a light chain comprising a light chain variable (VL) domain, wherein the VL domain comprises the amino acid sequence of SEQ ID NO: 7.
A method for asynchronous traceable data sharing between a sharing node and at least one recipient node for use in a communication network, wherein the communication network comprises a first gatekeeping server having access to a first metadata store , a first data store and a first repository comprising public keys associated with user entities, and wherein the method comprises the following steps: a) first, at the first gatekeeping server , receiving a request to share data with a recipient user entity from a sharing node associated with a sharing user entity; b) at the first gatekeeping server , retrieving a cryptographic public key associated with the recipient user entity from said repository and transmitting the key to the sharing node ; c) at the sharing node , receiving said public key , and encrypting at least part of the data using the recipient user entity's public key; d) transmitting said encrypted data , and metadata associated with said encrypted data, comprising a hash of the encrypted data or of said data, from the sharing node to the first gatekeeping server ; e) at the first gatekeeping server , receiving the encrypted data and storing it in the first data store ; f) at the first gatekeeping server , receiving the metadata and storing it in the first metadata store , including an address of said encrypted data in said first data store; g) at the first gatekeeping server , subsequently receiving a data retrieval request from a recipient node associated with said recipient user entity, retrieving said address from the first metadata store , retrieving said encrypted data at said address from said first data store , and transmitting said encrypted data to the recipient node . a) first, at the first gatekeeping server , receiving a request to share data with a recipient user entity from a sharing node associated with a sharing user entity; b) at the first gatekeeping server , retrieving a cryptographic public key associated with the recipient user entity from said repository and transmitting the key to the sharing node ; c) at the sharing node , receiving said public key , and encrypting at least part of the data using the recipient user entity's public key; d) transmitting said encrypted data , and metadata associated with said encrypted data, comprising a hash of the encrypted data or of said data, from the sharing node to the first gatekeeping server ; e) at the first gatekeeping server , receiving the encrypted data and storing it in the first data store ; f) at the first gatekeeping server , receiving the metadata and storing it in the first metadata store , including an address of said encrypted data in said first data store; g) at the first gatekeeping server , subsequently receiving a data retrieval request from a recipient node associated with said recipient user entity, retrieving said address from the first metadata store , retrieving said encrypted data at said address from said first data store , and transmitting said encrypted data to the recipient node .
A construction machine comprising: a lower travelling body ; an upper slewing body provided on the lower travelling body to be turnable with respect to the lower travelling body ; an obstacle detection sensor which is configured to detect presence/absence of an obstacle in a monitoring region set around the construction machine in advance and a distance to the obstacle; a first calculation portion which is configured to calculate first position information including positional coordinates of the obstacle relative to a reference position set in the construction machine in advance based on a detection result obtained by the obstacle detection sensor ; characterised in that the obstacle detection sensor is configured to further include a time information holding portion which has time information for specifying time when the obstacle is detected; and a storage unit which is configured to store log data that correlates the first position information with the time information. a lower travelling body ; an upper slewing body provided on the lower travelling body to be turnable with respect to the lower travelling body ; an obstacle detection sensor which is configured to detect presence/absence of an obstacle in a monitoring region set around the construction machine in advance and a distance to the obstacle; a first calculation portion which is configured to calculate first position information including positional coordinates of the obstacle relative to a reference position set in the construction machine in advance based on a detection result obtained by the obstacle detection sensor ; characterised in that the obstacle detection sensor is configured to further include a time information holding portion which has time information for specifying time when the obstacle is detected; and a storage unit which is configured to store log data that correlates the first position information with the time information.
A surface-enhanced Raman scattering unit comprising: a measurement board used upon measurement; a surface-enhanced Raman scattering element , secured to the measurement board , having a substrate and an optical function part, formed on the substrate, for generating surface-enhanced Raman scattering; and a pressing member (4; 4a), secured to the measurement board , having a ring-shaped contact part contacting with a peripheral part of the surface-enhanced Raman scattering element and pressing the surface-enhanced Raman scattering element toward the measurement board , and which is further formed into a ring when seen in the thickness direction of the substrate, so that: an inner side face of the contact part and the surface of the surface-enhanced Raman scattering element form a space (S) on the surface-enhanced Raman scattering element , and upon measurement, a sample can be dropped or dispersed in the space (S) so as to be arranged on the optical function part, when the pressing member presses the surface-enhanced Raman scattering element . a measurement board used upon measurement; a surface-enhanced Raman scattering element , secured to the measurement board , having a substrate and an optical function part, formed on the substrate, for generating surface-enhanced Raman scattering; and a pressing member (4; 4a), secured to the measurement board , having a ring-shaped contact part contacting with a peripheral part of the surface-enhanced Raman scattering element and pressing the surface-enhanced Raman scattering element toward the measurement board , and which is further formed into a ring when seen in the thickness direction of the substrate, so that: an inner side face of the contact part and the surface of the surface-enhanced Raman scattering element form a space (S) on the surface-enhanced Raman scattering element , and upon measurement, a sample can be dropped or dispersed in the space (S) so as to be arranged on the optical function part, when the pressing member presses the surface-enhanced Raman scattering element . an inner side face of the contact part and the surface of the surface-enhanced Raman scattering element form a space (S) on the surface-enhanced Raman scattering element , and upon measurement, a sample can be dropped or dispersed in the space (S) so as to be arranged on the optical function part, when the pressing member presses the surface-enhanced Raman scattering element .
A method for producing manufactured T cells, comprising: inoculating a culture input population of cells comprising T cells from a subject in a culture medium comprising temsirolimus and an IL-2 signaling inhibitor, wherein said culture medium does not contain IL-2 and no IL-2 is added to said culture medium and wherein said temsirolimus is present in said culture medium at a concentration of at least 1 μM, and wherein said IL-2 signaling inhibitor is an anti-IL-2 receptor antibody or fragment thereof; adding IFN-α to said culture medium; incubating said T cells and culture medium to yield manufactured T cells; and harvesting said manufactured T cells. said temsirolimus is present in said culture medium at a concentration of at least 1 μM, and wherein said IL-2 signaling inhibitor is an anti-IL-2 receptor antibody or fragment thereof; adding IFN-α to said culture medium; incubating said T cells and culture medium to yield manufactured T cells; and harvesting said manufactured T cells.
A polyethylene yarn, wherein the polyethylene yarn includes a plurality of filaments each having a fineness of 1 to 5 g/9000m (denier), wherein the polyethylene yarn has a weight average molecular weight (Mw) of 50,000 to 99,000 g/mol and a polydispersity index (PDI) of 5 to 9, wherein in a strength-elongation curve of the polyethylene yarn obtained by measuring at ambient temperature, (i) elongation at strength of 1 g/d is 0.5 to 3 %, (ii) elongation at strength of 3 g/d is 5.5 to 10 %, and (iii) a difference between elongation at strength of 4 g/d and elongation at maximum strength is 5.5 to 25 %, and wherein the polyethylene yarn has toughness of 55 to 120 J/m 3 at ambient temperature and a crystallinity of 60 to 85%. wherein the polyethylene yarn includes a plurality of filaments each having a fineness of 1 to 5 g/9000m (denier), wherein the polyethylene yarn has a weight average molecular weight (Mw) of 50,000 to 99,000 g/mol and a polydispersity index (PDI) of 5 to 9, wherein in a strength-elongation curve of the polyethylene yarn obtained by measuring at ambient temperature, (i) elongation at strength of 1 g/d is 0.5 to 3 %, (ii) elongation at strength of 3 g/d is 5.5 to 10 %, and (iii) a difference between elongation at strength of 4 g/d and elongation at maximum strength is 5.5 to 25 %, and wherein the polyethylene yarn has toughness of 55 to 120 J/m 3 at ambient temperature and a crystallinity of 60 to 85%.
Building material for shielding electromagnetic waves by predominantly absorbing the electromagnetic waves, wherein the building material contains ferrous-oxide-containing aggregates and mineral binders, characterized in that electro-furnace slag is used as an aggregate, which is thermally treated as follows prior to being mixed with the mineral binder: - cooling of the electro-furnace slag removed from an electro-furnace in two phases, initially, in the air at 1000°C to 1200°C and subsequently in an abrupt manner, in a water bath; - reheating the electro-furnace slag to a temperature between 200°C and 700°C for a specified period of time in the air, resulting in a reduction of the FeO and Fe 2 O 3 content and an increase in the Fe 3 O 4 content in the electro-furnace slag. - cooling of the electro-furnace slag removed from an electro-furnace in two phases, initially, in the air at 1000°C to 1200°C and subsequently in an abrupt manner, in a water bath; - reheating the electro-furnace slag to a temperature between 200°C and 700°C for a specified period of time in the air, resulting in a reduction of the FeO and Fe 2 O 3 content and an increase in the Fe 3 O 4 content in the electro-furnace slag.
A method of verifying the integrity of a sensor signal, comprising: - establishing a noise signal on a signaling line of a sensor , - performing an analysis of the noise signal , and - transmitting check data indicative of a result of the analysis - receiving a sensor signal on a signaling line of a sensor , - receiving check data indicative of a result of an analysis of a noise signal on the signaling line , and - depending on the check data : selectively processing the sensor signal wherein the check data includes a cryptographic key, wherein the cryptographic key is required to process the sensor signal . - establishing a noise signal on a signaling line of a sensor , - performing an analysis of the noise signal , and - transmitting check data indicative of a result of the analysis - receiving a sensor signal on a signaling line of a sensor , - receiving check data indicative of a result of an analysis of a noise signal on the signaling line , and - depending on the check data : selectively processing the sensor signal wherein the check data includes a cryptographic key,
A system for inductive heating of an aircraft surface, characterised in that the system comprises: a conductive outer layer configured to be located on an outer portion of the aircraft surface ; a carbon nanotube, CNT, yarn configured to receive and conduct electrical current; and an insulator located between the conductive outer layer and the CNT yarn such that the electrical current flowing through the CNT yarn generates induction heating on the conductive outer layer. a conductive outer layer configured to be located on an outer portion of the aircraft surface ; a carbon nanotube, CNT, yarn configured to receive and conduct electrical current; and an insulator located between the conductive outer layer and the CNT yarn such that the electrical current flowing through the CNT yarn generates induction heating on the conductive outer layer.
A refrigeration cycle apparatus, comprising: a refrigeration cycle configured to circulate refrigerant; a heat exchanger unit configured to accommodate at least a heat exchanger of the refrigeration cycle ; and a controller configured to control the heat exchanger unit , the heat exchanger unit comprising an air-blowing fan , and a refrigerant detection unit configured to detect a concentration of leaked refrigerant and to output a detection signal to the controller , characterized in that the controller is configured to operate the air-blowing fan when detecting leakage of the refrigerant, and to stop the air-blowing fan triggered by becoming negative from positive of a temporal change of the concentration of the leaked refrigerant. a refrigeration cycle configured to circulate refrigerant; a heat exchanger unit configured to accommodate at least a heat exchanger of the refrigeration cycle ; and a controller configured to control the heat exchanger unit , the heat exchanger unit comprising an air-blowing fan , and a refrigerant detection unit configured to detect a concentration of leaked refrigerant and to output a detection signal to the controller , characterized in that an air-blowing fan , and a refrigerant detection unit configured to detect a concentration of leaked refrigerant and to output a detection signal to the controller , characterized in that the controller is configured to operate the air-blowing fan when detecting leakage of the refrigerant, and to stop the air-blowing fan triggered by becoming negative from positive of a temporal change of the concentration of the leaked refrigerant.
Tire building system comprising a first drum , a second drum and a plurality of first stations (S1) for performing tire building operations on said first drum and said second drum , wherein the tire building system further comprises a first support , a first carrier that carries the first drum with respect to the first support , a second support and a second carrier that carries the second drum with respect to the second support , wherein the first carrier is movable along the first support in a first positioning plane (P1) to position the first drum with respect to the plurality of first stations (S1), characterized in that the second carrier is movable along the second support in the same first positioning plane (P1) to position the second drum with respect to the plurality of first stations (S1), wherein the first support is arranged for supporting the first carrier from below the first positioning plane (P1) and wherein the second support is arranged for suspending the second carrier from above the first positioning plane (P1).
A vehicle drivetrain assembly comprising: a housing assembly ; a shaft that is disposed in the housing assembly and that rotates about an axis ; a clutch collar that is moveably disposed on the shaft and configured to move along the axis ; a clutch collar actuator mechanism that actuates the clutch collar , the clutch collar actuator mechanism includes: an actuator rod that extends along an actuation axis ; a fork that operatively connects the actuator rod to the clutch collar ; characterized in that the vehicle drivetrain assembly further comprises a cap that is disposed on the housing assembly and that has a port disposed along the actuation axis , a cavity , and a coupling ring that extends around the port and the actuation axis ; and an air bellow that receives the coupling ring and is disposed between the actuator rod and the cap , the air bellow including a mounting panel that has a pin that extends along the actuation axis and is received in a hole in an enlarged head of the actuator rod and an inflatable bladder that extends between the mounting panel and the cap ; wherein the clutch collar moves from a first position to a second position when the air bellow is inflated. a housing assembly ; a shaft that is disposed in the housing assembly and that rotates about an axis ; a clutch collar that is moveably disposed on the shaft and configured to move along the axis ; a clutch collar actuator mechanism that actuates the clutch collar , the clutch collar actuator mechanism includes: an actuator rod that extends along an actuation axis ; a fork that operatively connects the actuator rod to the clutch collar ; characterized in that the vehicle drivetrain assembly further comprises a cap that is disposed on the housing assembly and that has a port disposed along the actuation axis , a cavity , and a coupling ring that extends around the port and the actuation axis ; and an air bellow that receives the coupling ring and is disposed between the actuator rod and the cap , the air bellow including a mounting panel that has a pin that extends along the actuation axis and is received in a hole in an enlarged head of the actuator rod and an inflatable bladder that extends between the mounting panel and the cap ; an actuator rod that extends along an actuation axis ; a fork that operatively connects the actuator rod to the clutch collar ; characterized in that the vehicle drivetrain assembly further comprises a cap that is disposed on the housing assembly and that has a port disposed along the actuation axis , a cavity , and a coupling ring that extends around the port and the actuation axis ; and an air bellow that receives the coupling ring and is disposed between the actuator rod and the cap , the air bellow including a mounting panel that has a pin that extends along the actuation axis and is received in a hole in an enlarged head of the actuator rod and an inflatable bladder that extends between the mounting panel and the cap ; wherein the clutch collar moves from a first position to a second position when the air bellow is inflated.
Motor vehicle comprising at least one aerodynamic deflector device comprising a deflector member positioned at the front part of said vehicle, and said member comprising a deflector blade having a surface able to deflect streams of air passing beneath the vehicle when the latter is running in a forwards direction, and which is mounted such as to be able to move, making it able to pass reversibly from a position extending towards the front of the vehicle and in the longitudinal direction of the vehicle to an aerodynamically active position as a function of the speed of the vehicle travelling in a forwards direction, characterized in that said device comprises guide means for guiding an air flow (A) arriving from the front of the vehicle towards said deflector blade , at least when said deflector blade is in the position extending towards the front of the vehicle and in the longitudinal direction of the vehicle, in the inactive position, and in that said guide means for guiding the air flow arriving from the front of the vehicle towards said deflector blade comprise at least one air inlet orifice formed by an upper orifice that allows an air flow arriving at the front of the vehicle to enter, and at least one air outlet orifice formed by a lower orifice opening above said blade in the position extending towards the front of the vehicle and in the longitudinal direction of the vehicle.
Method for compensation of an interference sound in a hearing aid by - determining a spectral band depending on a hearing ability , - filtering an input signal of the hearing aid , which represents a sound causing the interference sound , in the spectral band according to a transmission function (46,H'), which is measured in the spectral band according to a transmission function (47,H) for the sound on an interference sound path , and - generating a compensation sound by means of the input signal in inverted and filtered form. - determining a spectral band depending on a hearing ability , - filtering an input signal of the hearing aid , which represents a sound causing the interference sound , in the spectral band according to a transmission function (46,H'), which is measured in the spectral band according to a transmission function (47,H) for the sound on an interference sound path , and - generating a compensation sound by means of the input signal in inverted and filtered form.