mhurhangee/patent-ind-claim-en huggingface dataset:
A method of predicting a likelihood of a clinical outcome selected from cancer recurrence, upgrading or upstaging of cancer, adverse pathology, non-organ-confined disease, high-grade disease, and/or high-grade non-organ-confined disease for a patient with prostate cancer, comprising: determining a level of RNA transcripts, or expression products thereof, normalized relative to the mean of one or more reference genes in a biological sample containing cancer cells obtained from said patient, wherein the RNA transcripts, or expression products thereof, comprise BGN and COL1A1; calculating a recurrence score for the patient using any one of algorithms RS0, RS1, RS2, RS3, RS4, RS17, RS18, RS19, RS20, RS21, RS22, RS23, RS24, RS25, RS26, or RS27 shown in Table 4; and predicting the likelihood of cancer recurrence, upgrading or upstaging of cancer, adverse pathology, non-organ-confined disease, high-grade disease, and/or high-grade non-organ-confined disease for the patient based on the recurrence score. determining a level of RNA transcripts, or expression products thereof, normalized relative to the mean of one or more reference genes in a biological sample containing cancer cells obtained from said patient, wherein the RNA transcripts, or expression products thereof, comprise BGN and COL1A1; calculating a recurrence score for the patient using any one of algorithms RS0, RS1, RS2, RS3, RS4, RS17, RS18, RS19, RS20, RS21, RS22, RS23, RS24, RS25, RS26, or RS27 shown in Table 4; and predicting the likelihood of cancer recurrence, upgrading or upstaging of cancer, adverse pathology, non-organ-confined disease, high-grade disease, and/or high-grade non-organ-confined disease for the patient based on the recurrence score.
A method of detecting Quick User Datagram Protocol Internet Connections, QUIC, traffic in a telecommunication network between a User Equipment , UE, and a Content Provider , CP, wherein said UE has an established application session with said CP, for a particular application, using QUIC as transport protocol, wherein said method comprises: - receiving , by a User Plane Function, UPF , comprised by said telecommunication network, from said CP, a list of QUIC connection identifiers that identify said established application session between said UE and said CP, wherein the list comprises three to five, five to eight, or eight to twenty QUIC connection identifiers; - receiving , by said UPF, a QUIC packet comprising a QUIC connection identifier; - detecting , by said UPF, said QUIC traffic by determining that said QUIC connection identifier of said received QUIC packet is comprised by said list of QUIC connection identifiers. - receiving , by a User Plane Function, UPF , comprised by said telecommunication network, from said CP, a list of QUIC connection identifiers that identify said established application session between said UE and said CP, wherein the list comprises three to five, five to eight, or eight to twenty QUIC connection identifiers; - receiving , by said UPF, a QUIC packet comprising a QUIC connection identifier; - detecting , by said UPF, said QUIC traffic by determining that said QUIC connection identifier of said received QUIC packet is comprised by said list of QUIC connection identifiers.
Layer construction apparatus for the additive manufacturing of at least one component region of a component using an additive layer construction method, the apparatus comprising: - at least one coater for applying at least one powder layer of a material to a build-up and joining region ; - at least one radiation source for generating at least one energy beam for layer-wise and local melting and/or sintering of the material to form a component layer by selective irradiation of the material with the at least one energy beam in accordance with a predetermined exposure strategy; and - a flow device by means of which a fluid flow can be generated over the powder layer, which for this purpose has a nozzle-like outlet opening and an inlet opening , arranged opposite the outlet opening , for the fluid, between which openings the fluid flow is generated characterized by at least one flow guide device , which comprises at least one guide element for guiding the fluid flow over at least one region of the powder layer, at least the at least one guide element of the flow guide device being arranged within a process chamber of the layer construction apparatus , the at least one guide element being designed in the manner of a wall or plate, the at least one guide element being aligned perpendicularly to the powder layer and the guide surface of the at least one guide element being arranged parallel to the fluid flow and the flow guide device comprising a drive device which can be controlled in an open-loop and/or closed-loop manner and by means of which the at least one guide element is moved relative to the powder layer when it is in the traversing path of the coater during application of a new layer of powder. - at least one coater for applying at least one powder layer of a material to a build-up and joining region ; - at least one radiation source for generating at least one energy beam for layer-wise and local melting and/or sintering of the material to form a component layer by selective irradiation of the material with the at least one energy beam in accordance with a predetermined exposure strategy; and - a flow device by means of which a fluid flow can be generated over the powder layer, which for this purpose has a nozzle-like outlet opening and an inlet opening , arranged opposite the outlet opening , for the fluid, between which openings the fluid flow is generated
A composition comprising at least one pentacyclic triterpene or one of the pharmaceutically acceptable salts thereof for use in the treatment and/or prevention of an oral-dental pathology, wherein the at least one pentacyclic triterpene is a mix of celastrol, tingenin A, and tingenin B.
A tetracarboxylic dianhydride, which is a compound represented by the following general formula : [in the formula , multiple R 1 s each independently represent one selected from the group consisting of a hydrogen atom, alkyl groups having 1 to 10 carbon atoms, a hydroxy group, and a nitro group, or two R 1 s connected to a common carbon atom may together form a methylidene group, and R 2 and R 3 each independently represent one selected from the group consisting of a hydrogen atom and alkyl groups having 1 to 10 carbon atoms]. [in the formula , multiple R 1 s each independently represent one selected from the group consisting of a hydrogen atom, alkyl groups having 1 to 10 carbon atoms, a hydroxy group, and a nitro group, or two R 1 s connected to a common carbon atom may together form a methylidene group, and R 2 and R 3 each independently represent one selected from the group consisting of a hydrogen atom and alkyl groups having 1 to 10 carbon atoms].
Method for manufacturing an internal shell of a composite type IV reservoir delimiting an internal cavity intended to accommodate a pressurized fluid and comprising at least one metal baseplate allowing connection between said internal cavity and the outside of the internal shell, said baseplate or baseplates being secured to the internal shell, said method comprising the following steps: a) a step of applying at least one adhesive layer of a first polymer to the part or parts of the metal baseplate or baseplates intended to be in direct contact with the material of which the internal shell is made, said first polymer being a polymer comprising groups capable of adhering to a metal surface by the formation of covalent bonds, said groups being chosen from among maleic anhydride groups, silane groups, silanol groups, acrylic groups, peroxide groups and combinations of these groups; b) a step of incorporating said baseplate or baseplates thus coated into a mould the internal cavity of which has a shape that corresponds to the shape of the internal shell that is to be obtained; c) a step of forming, on the internal wall of the mould and on the part or parts of the baseplate or baseplates intended to be in contact with the material of which the internal shell is made, at least one layer of a second polymer different from said first polymer and adhering to the first polymer, thus forming the aforementioned internal shell equipped with the aforementioned baseplate or baseplates, said second polymer being a polymer in which some of its repetitive units are identical to these of the first polymer. a) a step of applying at least one adhesive layer of a first polymer to the part or parts of the metal baseplate or baseplates intended to be in direct contact with the material of which the internal shell is made, said first polymer being a polymer comprising groups capable of adhering to a metal surface by the formation of covalent bonds, said groups being chosen from among maleic anhydride groups, silane groups, silanol groups, acrylic groups, peroxide groups and combinations of these groups; b) a step of incorporating said baseplate or baseplates thus coated into a mould the internal cavity of which has a shape that corresponds to the shape of the internal shell that is to be obtained; c) a step of forming, on the internal wall of the mould and on the part or parts of the baseplate or baseplates intended to be in contact with the material of which the internal shell is made, at least one layer of a second polymer different from said first polymer and adhering to the first polymer, thus forming the aforementioned internal shell equipped with the aforementioned baseplate or baseplates, said second polymer being a polymer in which some of its repetitive units are identical to these of the first polymer.
An elevator system , comprising: an elevator car having an inner wall and a passenger space ; and an electronic visual display mounted to the inner wall so as to define a gap between the inner wall and the electronic visual display , wherein fluid (F 2 ) is configured to flow through the gap to cool the electronic visual display ; a first flow path through which fluid (F 1 ) is configured to flow to cool the passenger space ; and a second flow path through which fluid (F 2 ) is configured to flow to cool the electronic visual display ; wherein the passenger space is fluidly coupled to a source of fluid by a first flow path inlet configured to direct fluid (F 1 ) into the passenger space beneath the electronic visual display , and the passenger space is fluidly coupled to a location outside the elevator car by a first flow path outlet arranged above the electronic visual display . an elevator car having an inner wall and a passenger space ; and an electronic visual display mounted to the inner wall so as to define a gap between the inner wall and the electronic visual display , wherein fluid (F 2 ) is configured to flow through the gap to cool the electronic visual display ; a first flow path through which fluid (F 1 ) is configured to flow to cool the passenger space ; and a second flow path through which fluid (F 2 ) is configured to flow to cool the electronic visual display ; wherein the passenger space is fluidly coupled to a source of fluid by a first flow path inlet configured to direct fluid (F 1 ) into the passenger space beneath the electronic visual display , and the passenger space is fluidly coupled to a location outside the elevator car by a first flow path outlet arranged above the electronic visual display .
Pultrusion method for producing a fibre-reinforced plastic profile, comprising at least the following steps: - arranging a number of fibre rovings so as to form a unidirectional preliminary fibre profile with a defined first cross section, - applying at least one scrim to the unidirectional preliminary fibre profile to produce a layered structure , preferably a multidirectional layered structure, each scrim comprising lateral edge portions , - arranging two lateral edge portions in an overlapping manner to produce a common overlapping portion , characterized in that the method additionally comprises a step of form- and/or force-fittingly connecting the two overlapping lateral edge portions in the overlapping portion by means of sewing, tufting and/or clamping. - arranging a number of fibre rovings so as to form a unidirectional preliminary fibre profile with a defined first cross section, - applying at least one scrim to the unidirectional preliminary fibre profile to produce a layered structure , preferably a multidirectional layered structure, each scrim comprising lateral edge portions , - arranging two lateral edge portions in an overlapping manner to produce a common overlapping portion , characterized in that the method additionally comprises a step of form- and/or force-fittingly connecting the two overlapping lateral edge portions in the overlapping portion by means of sewing, tufting and/or clamping.
A suturing device needle, comprising: a flywheel portion ; at least one curved arm extending from the flywheel portion , the at least one curved arm comprising a ferrule engaging tip at an end of the at least one curved arm away from the flywheel portion , characterized in that a mass of the flywheel portion is greater than or equal to the mass of the one or more curved arms of the needle . a flywheel portion ; at least one curved arm extending from the flywheel portion , the at least one curved arm comprising a ferrule engaging tip at an end of the at least one curved arm away from the flywheel portion , characterized in that a mass of the flywheel portion is greater than or equal to the mass of the one or more curved arms of the needle .
A method comprising: transmitting and receiving a test signal for calibration between a plurality of electrodes of a device , the plurality of electrodes being coupled to the body of a user ; obtaining impedance of the body of the user based on the test signal; determining calibration information based on the impedance of the body of the user, and storing the determined calibration information in a profile for the user; receiving, by at least one of the plurality of electrodes coupled to the body of the user , an electromagnetic interference, EMI, signal through the body of the user, the EMI signal being emitted by an object that is external to the device ; comparing, by one or more processors , the received EMI signal to stored data, wherein the stored data includes the profile for the user and a data store associating EMI signals with a particular noise, environmental factor or location; and determining, by the one or more processors , a context surrounding the device based on the result of the comparison. transmitting and receiving a test signal for calibration between a plurality of electrodes of a device , the plurality of electrodes being coupled to the body of a user ; obtaining impedance of the body of the user based on the test signal; determining calibration information based on the impedance of the body of the user, and storing the determined calibration information in a profile for the user; receiving, by at least one of the plurality of electrodes coupled to the body of the user , an electromagnetic interference, EMI, signal through the body of the user, the EMI signal being emitted by an object that is external to the device ; comparing, by one or more processors , the received EMI signal to stored data, wherein the stored data includes the profile for the user and a data store associating EMI signals with a particular noise, environmental factor or location; and determining, by the one or more processors , a context surrounding the device based on the result of the comparison.
A ceramic vaporization core, comprising: a porous body ; and a heating body disposed on the porous body , wherein the porous body comprises at least one porous ceramic layer doped with hydroxyl group-containing matrix; characterized in that the at least one porous ceramic layer doped with hydroxyl group-containing matrix comprises components in parts by weight as follows: 35 to 55 parts by the weight of ceramic powder doped with hydroxyl group compound; and 25 to 45 parts by the weight of pore-forming agent; and wherein the ceramic powder doped with hydroxyl group compound comprises components in parts by weight as follows: 70 to 80 parts by the weight of main blank material; 10 to 15 parts by the weight of albite; 10 to 15 parts by the weight of fat clay; and 1 to 5 parts by the weight of hydroxyapatite. a porous body ; and a heating body disposed on the porous body , wherein the porous body comprises at least one porous ceramic layer doped with hydroxyl group-containing matrix; characterized in that the at least one porous ceramic layer doped with hydroxyl group-containing matrix comprises components in parts by weight as follows: 35 to 55 parts by the weight of ceramic powder doped with hydroxyl group compound; and 25 to 45 parts by the weight of pore-forming agent; and wherein the ceramic powder doped with hydroxyl group compound comprises components in parts by weight as follows: 70 to 80 parts by the weight of main blank material; 10 to 15 parts by the weight of albite; 10 to 15 parts by the weight of fat clay; and 1 to 5 parts by the weight of hydroxyapatite. 35 to 55 parts by the weight of ceramic powder doped with hydroxyl group compound; and 25 to 45 parts by the weight of pore-forming agent; and wherein the ceramic powder doped with hydroxyl group compound comprises components in parts by weight as follows: 70 to 80 parts by the weight of main blank material; 10 to 15 parts by the weight of albite; 10 to 15 parts by the weight of fat clay; and 1 to 5 parts by the weight of hydroxyapatite. 70 to 80 parts by the weight of main blank material; 10 to 15 parts by the weight of albite; 10 to 15 parts by the weight of fat clay; and 1 to 5 parts by the weight of hydroxyapatite.
An immunoglobulin single variable domain that specifically binds to the EL1 extracellular loop of potassium channel 3 (Kv1.3), wherein the immunoglobulin single variable domain modulates the activity of Kv1.3 by reducing by at least 70% or even totally inhibiting the efflux of potassium ions from T-cells, as determined in Patch Clamp assay; wherein the immunoglobulin single variable domain essentially consists of 4 framework regions (FR1 to FR4, respectively) and 3 complementarity determining regions (CDR1 to CDR3, respectively), in which: i) CDR1 is chosen from the group consisting of SEQ ID NOs: 181-210; and ii) CDR2 is chosen from the group consisting of SEQ ID NOs: 268-289 and SEQ ID NOs: 541-555; and iii) CDR3 is chosen from the group consisting of SEQ ID NOs: 393-415. i) CDR1 is chosen from the group consisting of SEQ ID NOs: 181-210; and ii) CDR2 is chosen from the group consisting of SEQ ID NOs: 268-289 and SEQ ID NOs: 541-555; and iii) CDR3 is chosen from the group consisting of SEQ ID NOs: 393-415.
Measuring module for a diffuse reflectance photometric analysis of one or more samples, comprising the following features: - a transmitter device with a transmission channel for emitting measuring radiation toward the location of the sample ; - a first focusing device for focusing the measuring radiation on the sample; - a receiver device with a reception channel for receiving the radiation reflected by the sample; - a second focusing device for focusing the measuring radiation reflected by the sample onto the receiver device , wherein the second focusing device comprises a filter , characterized in that the second focusing device consists of plastic and the filter , which is vapour deposited onto the second focusing device, is embodied to filter secondary radiation, such as for example autofluorescence of the sample, secondary maxima of the light source or transmitter device, ambient light or the like from the sample, excited by the measuring radiation. - a transmitter device with a transmission channel for emitting measuring radiation toward the location of the sample ; - a first focusing device for focusing the measuring radiation on the sample; - a receiver device with a reception channel for receiving the radiation reflected by the sample; - a second focusing device for focusing the measuring radiation reflected by the sample onto the receiver device , wherein the second focusing device comprises a filter , characterized in that the second focusing device consists of plastic and the filter , which is vapour deposited onto the second focusing device, is embodied to filter secondary radiation, such as for example autofluorescence of the sample, secondary maxima of the light source or transmitter device, ambient light or the like from the sample, excited by the measuring radiation.
Method of detecting a change in process water flow of a circulation pump in an appliance for washing and rinsing goods, comprising: measuring (S101) a property indicating torque of the circulation pump; averaging (S102) a first set of values of the measured property, thereby creating a first average; averaging (S103) at least a further set of values of the measured property, thereby creating at least one further average; comparing (S104) the first average with the at least one further average; and detecting (S105) the change in process water flow of the circulation pump based on a difference between the first average and the at least one further average. measuring (S101) a property indicating torque of the circulation pump; averaging (S102) a first set of values of the measured property, thereby creating a first average; averaging (S103) at least a further set of values of the measured property, thereby creating at least one further average; comparing (S104) the first average with the at least one further average; and detecting (S105) the change in process water flow of the circulation pump based on a difference between the first average and the at least one further average.
Method for cooling a plate in a cooling section , wherein the cooling section has - a roller table for transporting the plate in the direction of transport (T) through the cooling section , - at least one variable-flow cooling nozzle , - at least one detector for determining the speed of the plate in the cooling section , and - an adjustment device for setting the volume of coolant through the cooling nozzle , characterised by the following method steps: - cutting off the plate from a finished strip after the final rolling stand of the finishing train and before the plate enters the cooling section , - accelerating the cut plate on the roller table , in order to generate as much intermediate space as possible between the finished strip and the plate , - transporting the plate through the cooling section , - detecting the speed of the plate in the cooling section , - supplying the speed to the adjustment device , and - setting the volume of coolant through the cooling nozzle as a function of the speed by means of the adjustment device , such that the plate is uniformly cooled. - a roller table for transporting the plate in the direction of transport (T) through the cooling section , - at least one variable-flow cooling nozzle , - at least one detector for determining the speed of the plate in the cooling section , and - an adjustment device for setting the volume of coolant through the cooling nozzle , - cutting off the plate from a finished strip after the final rolling stand of the finishing train and before the plate enters the cooling section , - accelerating the cut plate on the roller table , in order to generate as much intermediate space as possible between the finished strip and the plate , - transporting the plate through the cooling section , - detecting the speed of the plate in the cooling section , - supplying the speed to the adjustment device , and - setting the volume of coolant through the cooling nozzle as a function of the speed by means of the adjustment device , such that the plate is uniformly cooled.