mhurhangee/patent-ind-claim-en huggingface dataset:
Wearable sitting posture assisting device, comprising at least one leg unit featuring at least one knee joint and featuring at least one locking unit for the knee joint ; comprising at least one second leg unit featuring at least one second knee joint and featuring at least one second locking unit ; and comprising at least one actuation unit (14a; 14f; 14g; 14h; 14i; 14j) featuring at least one manually operable actuation element (16a; 16g; 16h; 16i; 16j) for mechanically controlling the locking unit and/or the second locking unit , characterized in that the actuation unit comprises at least one transmission unit , which transmission unit is configured for at least partly transmitting an actuation force from the actuation element to the locking unit and/or to the second locking unit and which transmission unit is at least partly implemented as a Bowden cable.
A computer-implemented method for detecting phase-encoding ghosting in a MR image of an object to be imaged and mitigating the corresponding artifact in said MR image, the computer-implemented method comprising: - acquiring MRI raw data of the object by means of a MRI apparatus, wherein the MRI apparatus comprises multiple receiver channels for acquiring said MRI raw data; - calculating an artifact map of at least one part of the object to be imaged from the MRI raw data, comprising - generating a duplicate k-space data set by using GRAPPA interpolation kernels on said MRI raw data, such that said duplicate k-space data set consists in a fully-sampled centric-ordered and non-interleaved k-space data set; - obtaining the artifact map by subtracting the inverse Fourier transformed duplicate k-space data set with the inverse Fourier transformed MRI raw data; - creating an outlier mask representing detected phase-encoding artifacts in said artifact map by applying a threshold t to separate high intensity ghosting from background noise in the artifact map; - mitigating phase-encode ghosting in the MR image by using the previously obtained artifact map and the outlier mask for obtaining an improved MR image by replacing each image voxel of the inverse Fourier transformed MRI raw data that is indicated as artifactual in the outlier mask by the corresponding image voxel of the inverse Fourier transformed duplicate k-space data set. - acquiring MRI raw data of the object by means of a MRI apparatus, wherein the MRI apparatus comprises multiple receiver channels for acquiring said MRI raw data; - calculating an artifact map of at least one part of the object to be imaged from the MRI raw data, comprising - generating a duplicate k-space data set by using GRAPPA interpolation kernels on said MRI raw data, such that said duplicate k-space data set consists in a fully-sampled centric-ordered and non-interleaved k-space data set; - obtaining the artifact map by subtracting the inverse Fourier transformed duplicate k-space data set with the inverse Fourier transformed MRI raw data; - generating a duplicate k-space data set by using GRAPPA interpolation kernels on said MRI raw data, such that said duplicate k-space data set consists in a fully-sampled centric-ordered and non-interleaved k-space data set; - obtaining the artifact map by subtracting the inverse Fourier transformed duplicate k-space data set with the inverse Fourier transformed MRI raw data; - creating an outlier mask representing detected phase-encoding artifacts in said artifact map by applying a threshold t to separate high intensity ghosting from background noise in the artifact map; - mitigating phase-encode ghosting in the MR image by using the previously obtained artifact map and the outlier mask for obtaining an improved MR image by replacing each image voxel of the inverse Fourier transformed MRI raw data that is indicated as artifactual in the outlier mask by the corresponding image voxel of the inverse Fourier transformed duplicate k-space data set.
A computer-implemented method for providing information for selecting an anticancer agent using individual genome sequence variation, which comprises: a step of obtaining one or more sequence variations of a patient in genes determined to be involved in the pharmacodynamics or pharmacokinetics of an anticancer agent from individual genome sequence information; a step of calculating a protein damage score using [Equation 2], wherein S g v 1 , ... , v n = ∏ i = 1 n v i w i 1 / ∑ i = 1 n w i wherein Sg is the protein damage score of a protein encoded by a gene g, n is the number of the one or more sequence variations of the gene g, vi is a gene sequence variation score of an i th gene sequence variation, and w i is a weighting assigned to the gene sequence variation score vi of the i th gene sequence variation; and a step of calculating an individual drug score using [Equation 4], wherein S d g 1 , ... , g n = ∏ i = 1 n g i w i 1 / ∑ i = 1 n w i wherein S d is the individual drug score of an anticancer agent d, n is a number of proteins encoded by one or more genes involved in the pharmacodynamics or pharmacokinetics of the anticancer agent d, gi is a protein damage score of a protein encoded by one or more genes involved in the pharmacodynamics or pharmacokinetics of the anticancer agent d, and w i is a weighting assigned to the protein damage score gi of the protein encoded by one or more genes involved in the pharmacodynamics or pharmacokinetics of the anticancer agent d; and providing information for selecting an anticancer agent based on the calculation of the individual drug score. a step of obtaining one or more sequence variations of a patient in genes determined to be involved in the pharmacodynamics or pharmacokinetics of an anticancer agent from individual genome sequence information; a step of calculating a protein damage score using [Equation 2], wherein S g v 1 , ... , v n = ∏ i = 1 n v i w i 1 / ∑ i = 1 n w i wherein Sg is the protein damage score of a protein encoded by a gene g, n is the number of the one or more sequence variations of the gene g, vi is a gene sequence variation score of an i th gene sequence variation, and w i is a weighting assigned to the gene sequence variation score vi of the i th gene sequence variation; and a step of calculating an individual drug score using [Equation 4], wherein S d g 1 , ... , g n = ∏ i = 1 n g i w i 1 / ∑ i = 1 n w i wherein S d is the individual drug score of an anticancer agent d, n is a number of proteins encoded by one or more genes involved in the pharmacodynamics or pharmacokinetics of the anticancer agent d, gi is a protein damage score of a protein encoded by one or more genes involved in the pharmacodynamics or pharmacokinetics of the anticancer agent d, and w i is a weighting assigned to the protein damage score gi of the protein encoded by one or more genes involved in the pharmacodynamics or pharmacokinetics of the anticancer agent d; and providing information for selecting an anticancer agent based on the calculation of the individual drug score.
A water-insoluble drug for use in a method of reducing the risk of embolization of peripheral blood vessels, wherein the water-insoluble drug has a crystalline morphological form and wherein a plurality of crystal particles is regularly arranged and uniformly sized in a drug coating layer on the surface of a medical device having an expandable member, wherein the generation of microparticulates having a size that causes embolization of peripheral blood vessels is suppressed, wherein the plurality of crystal particles are elongated hollow bodies which are independently present and have one end fixed to the substrate surface, wherein the water-insoluble drug is selected from the group consisting of paclitaxel, rapamycin, docetaxel, and everolimus, and wherein the drug coating layer comprises excipient particles formed of an excipient that does not form a matrix, which are irregularly arranged between the crystal particles.
A cosmetic or dermatological composition comprising dihydromyricetin, a zinc salt and a lipophilic antioxidant, characterized in that the lipophilic antioxidant is chosen from propyl gallate, octyl gallate and dodecyl gallate.
Single device for shifting gears on a bicycle equipped with chainwheels and sprockets , a chain stretched between these chainwheels and sprockets, and a rear derailleur DR, said single device for shifting gears comprising a single casing which comprises: - means for changing chainwheels, comprising a chainwheel drum rotatably mounted about an axis XX', a track having an established profile formed in said drum, a drive finger capable of following the profile of said track , this finger being rigidly connected to a shaft carrying a fork which is capable of receiving the chain and causing the shifting of said chain from one chainwheel to another, - means for changing sprockets via the rear derailleur DR, and - means for controlling said means for changing chainwheels and said means for changing sprockets. - means for changing chainwheels, comprising a chainwheel drum rotatably mounted about an axis XX', a track having an established profile formed in said drum, a drive finger capable of following the profile of said track , this finger being rigidly connected to a shaft carrying a fork which is capable of receiving the chain and causing the shifting of said chain from one chainwheel to another, - means for changing sprockets via the rear derailleur DR, and - means for controlling said means for changing chainwheels and said means for changing sprockets.
Wind turbine installation comprising - a tower , - a nacelle , - a liquid immersed power electrical device having an expansion vessel , - an air dehydrating breather comprising a moisture absorbing agent , and - a conduit fluidly connecting the expansion vessel and the air dehydrating breather , wherein the wind turbine installation comprises a barrier separating a restricted zone from a non-restricted zone in said wind turbine installation , wherein the electrical device is located in the restricted zone , wherein the air dehydrating breather is located in the non-restricted zone and wherein the conduit extends through the barrier . - a tower , - a nacelle , - a liquid immersed power electrical device having an expansion vessel , - an air dehydrating breather comprising a moisture absorbing agent , and - a conduit fluidly connecting the expansion vessel and the air dehydrating breather ,
A surgical assembly, comprising: a housing ; a shaft comprising a longitudinal shaft axis; a shaft rotation joint configured to permit the shaft to rotate relative to the housing about the longitudinal shaft axis; an end effector comprising a longitudinal end effector axis; an articulation joint rotatably connecting the end effector to the shaft; an end effector rotation joint configured to permit the end effector to rotate relative to the shaft about the longitudinal end effector axis; a first electric motor configured to rotate the shaft about the longitudinal shaft axis; a first actuator configured to receive a first input from the user of the surgical assembly; a second electric motor configured to rotate the end effector about the longitudinal end effector axis; a second actuator configured to receive a second input from the user of the surgical instrument; and a motor control system configured to: rotate the first electric motor in response to the first input; rotate the second electric motor in response to the second input; and characterized in that the motor control system is further configured to: rotate the second electric motor in response to the first input to maintain a rotational alignment between the shaft and the end effector. a housing ; a shaft comprising a longitudinal shaft axis; a shaft rotation joint configured to permit the shaft to rotate relative to the housing about the longitudinal shaft axis; an end effector comprising a longitudinal end effector axis; an articulation joint rotatably connecting the end effector to the shaft; an end effector rotation joint configured to permit the end effector to rotate relative to the shaft about the longitudinal end effector axis; a first electric motor configured to rotate the shaft about the longitudinal shaft axis; a first actuator configured to receive a first input from the user of the surgical assembly; a second electric motor configured to rotate the end effector about the longitudinal end effector axis; a second actuator configured to receive a second input from the user of the surgical instrument; and a motor control system configured to: rotate the first electric motor in response to the first input; rotate the second electric motor in response to the second input; rotate the first electric motor in response to the first input; rotate the second electric motor in response to the second input;
Switch device with at least one contact point and one permanent magnetic arc blowing device associated with the contact point, wherein the arc blowing device comprises a first lateral pole plate (6.1), a second lateral pole plate (6.2), a central pole plate (6.3) arranged therebetween, and at least one first permanent magnet (2.1, 2.2) to generate a magnetic blow-out field, wherein the at least one first permanent magnet (2.1, 2.2) is arranged and is in contact with at least one of the pole plates (6.1, 6.2, 6.3) either directly or via a magnetic conductor such that a first magnetic field region of the blow-out field is provided between the first lateral pole plate (6.1) and the central pole plate (6.3), and such that a second magnetic field region of the blow-out field is provided between the second lateral pole plate (6.2) and the central pole plate (6.3), wherein the magnetic field lines of the first magnetic field region are aligned opposite the magnetic field lines of the second magnetic field region, and wherein the blow-out field additionally has a transition region which connects the first magnetic field region and the second magnetic field region together, wherein the magnetic field lines are aligned identically in each case starting from the first magnetic field region and the second magnetic field region toward the contact point in the transition region such that a switching arc (3.1, 3.2) produced within the transition region upon opening the contact point is conducted either into the first magnetic field region or into the second magnetic field region depending on the current direction from the contact point and in both cases is blown away in the same direction from the contact point in said region, characterized in that the arc blowing device has at least one second permanent magnet as an auxiliary magnet , wherein the auxiliary magnet is arranged in the direct vicinity of the contact point such that at least one section of the magnetic field of the auxiliary magnet amplifies the blow-out field in the transition region.
Portable container for free-flowing/spreadable material in its commercial packaging, for enabling the dosing and storage of the material and for opening the packaging wherein the container has a bottom wall on which it stands during storage, - wherein a side wall with a removal opening for the goods is provided in vertical or substantially vertical alignment with the base wall, - wherein a side wall is completely or largely missing or can be opened in vertical or largely vertical alignment to the base wall, opposite the side wall with the removal opening and aligned parallel or largely parallel thereto, in order to form the insertion opening for the packaging, - wherein the container has two side walls which are arranged perpendicularly or substantially perpendicularly to the side walls with removal opening and insertion opening and to the base wall, - wherein a cutting device projecting into the container is mounted around the removal opening in such a way that, after insertion of the commercial package into the container, a kind of flap is formed on the package which can be folded outwards without packaging material becoming completely detached, - wherein a metering device is attached to the outside of the container in front of the removal opening in such a way that material trickling out of the removal opening is collected by the latter, - wherein the cutting device does not run completely around the removal opening , but leaves out a section, characterized in that this recess is shorter than the maximum dimension of the removal opening, measured in the orientation of this recess. - wherein a side wall with a removal opening for the goods is provided in vertical or substantially vertical alignment with the base wall, - wherein a side wall is completely or largely missing or can be opened in vertical or largely vertical alignment to the base wall, opposite the side wall with the removal opening and aligned parallel or largely parallel thereto, in order to form the insertion opening for the packaging, - wherein the container has two side walls which are arranged perpendicularly or substantially perpendicularly to the side walls with removal opening and insertion opening and to the base wall, - wherein a cutting device projecting into the container is mounted around the removal opening in such a way that, after insertion of the commercial package into the container, a kind of flap is formed on the package which can be folded outwards without packaging material becoming completely detached, - wherein a metering device is attached to the outside of the container in front of the removal opening in such a way that material trickling out of the removal opening is collected by the latter, - wherein the cutting device does not run completely around the removal opening , but leaves out a section,
A tooling for the coating of lips of a turbomachine rotor sector , comprising a support for a rotor sector , a centering plate adapted to be inserted into a rotor sector , said centering plate having a central housing , a tool , characterized by said tool comprising a centering arm , adapted to be inserted into the central housing of the centering plate , a torch , adapted to spray a ceramic material, a machining tool , said tooling being configured so as to position the tool relative to the rotor sector via the centering plate , and to simultaneously perform on the rotor sector a spraying of ceramic material and a machining on two distinct sectors of the lips .
Method for operating a plurality of antennas of a vehicle , in which the vehicle communicates wirelessly with an external radio station while travelling through a radio cell of the external radio station by means of a radio signal emitted by the multiple antennas , characterised in that a signal strength and a directional characteristic of the emitted radio signal is adjusted depending on the accuracy of a determined relative position of the external radio station .
An ultrasonic waveguide , comprising: a shaft comprising a proximal end and a distal end, wherein the proximal end is configured to couple to an ultrasonic transducer and the distal end defines cylindrical aperture with a flat perpendicular bottom configured to receive a proximal end of a blade; and a blade attached to the shaft, the blade comprising a distal end for treating tissue and a proximal end defining a conical male end defining a flat perpendicular bottom , wherein the conical male end defines a proximal diameter (Φ 1 ) and a distal diameter (Φ 2 ), wherein the proximal diameter is larger than the distal diameter, and wherein the conical male end is received into the cylindrical aperture defined by the distal end of the shaft. a shaft comprising a proximal end and a distal end, wherein the proximal end is configured to couple to an ultrasonic transducer and the distal end defines cylindrical aperture with a flat perpendicular bottom configured to receive a proximal end of a blade; and a blade attached to the shaft, the blade comprising a distal end for treating tissue and a proximal end defining a conical male end defining a flat perpendicular bottom , wherein the conical male end defines a proximal diameter (Φ 1 ) and a distal diameter (Φ 2 ), wherein the proximal diameter is larger than the distal diameter, and wherein the conical male end is received into the cylindrical aperture defined by the distal end of the shaft.
A medicament device sensor configured for removable attachment to a medicament device , the medicament device sensor comprising: a body comprising a first wall, a second wall, and a bottom surface: the bottom surface configured to mate to a complementary outer surface of a medicament device ; and the first wall coupled to an edge of the bottom surface and comprising: a securement clip configured to attach the first wall of the medicament device sensor to a ledge on a complementary surface of the medicament device in a fixed orientation; characterized by a release tab having a topmost surface contiguous with a topmost surface of the first wall, the release tab configured to rotate the securement clip when pressed such that the medicament device can slide relative to the medicament device sensor ; and one or more sensors coupled to the bottom surface , each of the one or more sensors configured to signals indicating a use of the medicament device . a body comprising a first wall, a second wall, and a bottom surface: the bottom surface configured to mate to a complementary outer surface of a medicament device ; and the first wall coupled to an edge of the bottom surface and comprising: a securement clip configured to attach the first wall of the medicament device sensor to a ledge on a complementary surface of the medicament device in a fixed orientation; characterized by a release tab having a topmost surface contiguous with a topmost surface of the first wall, the release tab configured to rotate the securement clip when pressed such that the medicament device can slide relative to the medicament device sensor ; and the bottom surface configured to mate to a complementary outer surface of a medicament device ; and the first wall coupled to an edge of the bottom surface and comprising: a securement clip configured to attach the first wall of the medicament device sensor to a ledge on a complementary surface of the medicament device in a fixed orientation; characterized by a release tab having a topmost surface contiguous with a topmost surface of the first wall, the release tab configured to rotate the securement clip when pressed such that the medicament device can slide relative to the medicament device sensor ; and a securement clip configured to attach the first wall of the medicament device sensor to a ledge on a complementary surface of the medicament device in a fixed orientation; characterized by a release tab having a topmost surface contiguous with a topmost surface of the first wall, the release tab configured to rotate the securement clip when pressed such that the medicament device can slide relative to the medicament device sensor ; and one or more sensors coupled to the bottom surface , each of the one or more sensors configured to signals indicating a use of the medicament device .