mhurhangee/patent-ind-claim-en huggingface dataset:
An oral film consisting essentially of dexamethasone and hydroxypropyl methylcellulose, wherein the concentration of dexamethasone is 30% w/w or more and the concentration of hydroxypropyl methylcellulose is between 35 and 70% w/w based on total dry matter.
A split collet of which the central opening designed to receive a balance staff is noncircular, the split collet comprising a split , wherein the contour of the central opening comprises a limited number greater than two of bearing portions designed to interact with said balance staff, wherein at least two bearing portion (4, 5 or 14, 15) are situated on arms (6, 7 or 27, 28) and wherein the collet comprises recesses between: - the arms, and - the portions that are adjacent to the arms, the adjacent portions being constituted by the collet, the recesses maximizing the length of the elastic zone of the collet, which then extends up to the split and covers an arc of almost 180° on each half of the collet. - the arms, and - the portions that are adjacent to the arms, the adjacent portions being constituted by the collet, the recesses maximizing the length of the elastic zone of the collet, which then extends up to the split and covers an arc of almost 180° on each half of the collet. the adjacent portions being constituted by the collet, the recesses maximizing the length of the elastic zone of the collet, which then extends up to the split and covers an arc of almost 180° on each half of the collet.
A pharmaceutical composition comprising an antibody or antigen-binding fragment thereof that specifically binds to interleukin-4 receptor (IL-4R) for use in treating moderate to severe uncontrolled asthma in a subject, wherein the treatment comprises administering to the subject a combination therapy comprising: i) one or more maintenance doses of an inhaled corticosteroid (ICS), ii) one or more maintenance doses of a long-acting beta2-adrenergic agonist (LABA), and iii) a loading dose of about 600 mg of the antibody or antigen-binding fragment thereof, and one or more maintenance doses of about 300 mg of the antibody or antigen-binding fragment thereof, wherein the antibody or antigen-binding fragment thereof comprises a heavy chain variable region (HCVR) comprising the amino acid sequence of SEQ ID NO: 1 and a light chain variable region (LCVR) comprising the amino acid sequence of SEQ ID NO: 2, wherein the one or more maintenance doses of the antibody or antigen-binding fragment thereof are administered every other week (q2w), and wherein the ICS and LABA are administered for the duration of administration of the IL-4R antagonist. i) one or more maintenance doses of an inhaled corticosteroid (ICS), ii) one or more maintenance doses of a long-acting beta2-adrenergic agonist (LABA), and iii) a loading dose of about 600 mg of the antibody or antigen-binding fragment thereof, and one or more maintenance doses of about 300 mg of the antibody or antigen-binding fragment thereof, wherein the antibody or antigen-binding fragment thereof comprises a heavy chain variable region (HCVR) comprising the amino acid sequence of SEQ ID NO: 1 and a light chain variable region (LCVR) comprising the amino acid sequence of SEQ ID NO: 2, wherein the one or more maintenance doses of the antibody or antigen-binding fragment thereof are administered every other week (q2w), and wherein the ICS and LABA are administered for the duration of administration of the IL-4R antagonist.
An ultrasound imaging system comprising: an ultrasound transducer array comprising a plurality of ultrasound transducer tiles (101a-d), each of said tiles having an independently adjustable orientation such as to conform an ultrasound transmitting surface of the tile to a region of a body ; and a user interface including a processing arrangement coupled to the ultrasound transducer array and configured to register the ultrasound transducer tiles by: receiving respective ultrasound images (111a-d) from at least some of the ultrasound transducer tiles when the ultrasound transducer array is positioned on said region; identifying, using a known spatial arrangement of a plurality of features (201-204) of a foreign object located within the body, the position and location of said foreign object in a set of received individual ultrasound images each comprising at least some of said features; and generating a composite ultrasound image from the individual ultrasound images in said set by superimposing the identified respective positions and orientations of the foreign object in the individual ultrasound images. an ultrasound transducer array comprising a plurality of ultrasound transducer tiles (101a-d), each of said tiles having an independently adjustable orientation such as to conform an ultrasound transmitting surface of the tile to a region of a body ; and a user interface including a processing arrangement coupled to the ultrasound transducer array and configured to register the ultrasound transducer tiles by: receiving respective ultrasound images (111a-d) from at least some of the ultrasound transducer tiles when the ultrasound transducer array is positioned on said region; identifying, using a known spatial arrangement of a plurality of features (201-204) of a foreign object located within the body, the position and location of said foreign object in a set of received individual ultrasound images each comprising at least some of said features; and generating a composite ultrasound image from the individual ultrasound images in said set by superimposing the identified respective positions and orientations of the foreign object in the individual ultrasound images. receiving respective ultrasound images (111a-d) from at least some of the ultrasound transducer tiles when the ultrasound transducer array is positioned on said region; identifying, using a known spatial arrangement of a plurality of features (201-204) of a foreign object located within the body, the position and location of said foreign object in a set of received individual ultrasound images each comprising at least some of said features; and generating a composite ultrasound image from the individual ultrasound images in said set by superimposing the identified respective positions and orientations of the foreign object in the individual ultrasound images.
Method for controlling a drive apparatus of a micro-oscillation mirror , in which - at least one actuation signal is generated, and the drive apparatus is actuated therewith in such a way that it drives the micro-oscillation mirror in an oscillating fashion, - at least one position signal which characterizes the deflection of the micro-oscillation mirror is sensed, - the at least one actuation signal is closed-loop controlled on the basis of the at least one position signal in such a way that the micro-oscillation mirror is driven at its resonant frequency, characterized in that the amplitude of the at least one position signal is continuously compared with at least one threshold value , and at least one time interval between at least two passes of the at least one position signal through at least one threshold value is determined, and the at least one actuation signal is closed-loop controlled on the basis of the at least one time interval , wherein a time interval between a pass of the at least one position signal through a first threshold value and the next pass through a second threshold value on the same edge is determined and a deflection of the micro-oscillation mirror is determined therefrom. - at least one actuation signal is generated, and the drive apparatus is actuated therewith in such a way that it drives the micro-oscillation mirror in an oscillating fashion, - at least one position signal which characterizes the deflection of the micro-oscillation mirror is sensed, - the at least one actuation signal is closed-loop controlled on the basis of the at least one position signal in such a way that the micro-oscillation mirror is driven at its resonant frequency,
A polysaccharide derivative substituted (a) at a degree of substitution (DS1) of from at least 0.05 to 1.50 by a fluorescent group (FG) comprising a mono or polycyclic ring system comprising at least one heteroatom selected from N, O and S and conjugated double bonds, and having an absorption band in the UV region of light and an emission band in the visible region of light, and a bonded via a first linker to any one of the native functional groups of the polysaccharide repeating units; and (b) at a degree of substitution (DS2) of from at least 0.05 to 1.50 by a charged group (CG) bonded via a second linker to any one of the native functional groups of the polysaccharide repeating units. (a) at a degree of substitution (DS1) of from at least 0.05 to 1.50 by a fluorescent group (FG) comprising a mono or polycyclic ring system comprising at least one heteroatom selected from N, O and S and conjugated double bonds, and having an absorption band in the UV region of light and an emission band in the visible region of light, and a bonded via a first linker to any one of the native functional groups of the polysaccharide repeating units; and (b) at a degree of substitution (DS2) of from at least 0.05 to 1.50 by a charged group (CG) bonded via a second linker to any one of the native functional groups of the polysaccharide repeating units.
A method for implementing automatic instantiation of relevant code segments in a service mesh environment comprising: snooping at least one Uniform Resource Identifier from one or more response packets generated by an execution of a code segment from a plurality of code segments having a preferred execution sequence, wherein the at least one Uniform Resource Identifier at least identifies a next code segment in the preferred execution sequence; in response to snooping the at least one identifier and prior to receiving a request to instantiate the next code segment, preemptively instantiating the next code segment in the preferred execution sequence, wherein an initial code segment from the plurality of code segments is instantiated in response to a trigger. snooping at least one Uniform Resource Identifier from one or more response packets generated by an execution of a code segment from a plurality of code segments having a preferred execution sequence, wherein the at least one Uniform Resource Identifier at least identifies a next code segment in the preferred execution sequence; in response to snooping the at least one identifier and prior to receiving a request to instantiate the next code segment, preemptively instantiating the next code segment in the preferred execution sequence, wherein an initial code segment from the plurality of code segments is instantiated in response to a trigger.
A film comprising: a polyether ketone ketone resin (A) having a repeating unit (a-1) represented by structural formula and a repeating unit (a-2) represented by structural formula ; and a polybiphenyl ether sulfone resin (B) having a repeating unit (b) represented by general formula , a content ratio of the polybiphenyl ether sulfone resin (B) occupied in the total of the polyether ketone ketone resin (A) and the polybiphenyl ether sulfone resin (B) being from 10 to 70% by mass: wherein in the formula , at least any one of R 1 to R 4 represents a sulfonyl group, and at least any one thereof represents an oxygen atom, with the balance each independently representing any of an oxygen atom, a sulfur atom, a sulfonyl group, and a carbonyl group; Ar 1 to Ar 3 each independently represent an arylene group having from 6 to 24 carbon atoms; m represents 0 or 1; and n represents 0 or 1.
A method for preparing a solid dosage form comprising at least one antibody or functional fragment thereof, a surfactant, an extrusion-spheronization aid, a buffer, a disintegrant and at least one further excipient selected from the group consisting of fillers, sustained release agents and combinations thereof, comprising the steps of a) providing a powder blend comprising the extrusion-spheronization aid, the disintegrant, and the at least one further excipient; b) wet granulating by adding a binding liquid to the powder blend of step a) to obtain a wet mass; c) extruding the wet mass of step b) and collecting an extrudate; d) spheronizing the extrudate of step c) to obtain wet spheroids; e) drying the wet spheroids to obtain the solid dosage form; wherein the powder blend and/or the binding liquid comprises the at least one antibody or functional fragment thereof, the buffer, and the surfactant; and wherein the amount of surfactant relative to the total volume of the binding liquid (w/v) is from 0.05 to 2.0 %. a) providing a powder blend comprising the extrusion-spheronization aid, the disintegrant, and the at least one further excipient; b) wet granulating by adding a binding liquid to the powder blend of step a) to obtain a wet mass; c) extruding the wet mass of step b) and collecting an extrudate; d) spheronizing the extrudate of step c) to obtain wet spheroids; e) drying the wet spheroids to obtain the solid dosage form; wherein the powder blend and/or the binding liquid comprises the at least one antibody or functional fragment thereof, the buffer, and the surfactant; and wherein the amount of surfactant relative to the total volume of the binding liquid (w/v) is from 0.05 to 2.0 %. wherein the powder blend and/or the binding liquid comprises the at least one antibody or functional fragment thereof, the buffer, and the surfactant; and wherein the amount of surfactant relative to the total volume of the binding liquid (w/v) is from 0.05 to 2.0 %.
Method for the preparation of ammonia synthesis gas comprising the steps of (a) providing a hydrocarbon feed stock; (b) preparing a separate hydrogen stream and a separate oxygen stream by electrolysis of water; (c) providing process air for use in autothermal reforming by enriching atmospheric air with the oxygen stream from step (b); (d) autothermal reforming at least a part of the hydrocarbon feed stock with the oxygen enriched process air to a process gas stream comprising hydrogen, nitrogen, carbon monoxide and carbon dioxide; (e) treating the process gas stream obtained in the autothermal reforming step (d) in one or more water gas shift reactions; (f) removing the carbon dioxide from the water gas shift treated process gas stream; and (g) purifying the process gas stream from step (f); and (h) obtaining the ammonia synthesis gas, wherein at least a part of the hydrogen stream obtained in step (b)is added to process gas stream after step (g)in an amount to provide a molar ratio of the hydrogen to the nitrogen of 2.7-3.3 in the ammonia synthesis gas. (a) providing a hydrocarbon feed stock; (b) preparing a separate hydrogen stream and a separate oxygen stream by electrolysis of water; (c) providing process air for use in autothermal reforming by enriching atmospheric air with the oxygen stream from step (b); (d) autothermal reforming at least a part of the hydrocarbon feed stock with the oxygen enriched process air to a process gas stream comprising hydrogen, nitrogen, carbon monoxide and carbon dioxide; (e) treating the process gas stream obtained in the autothermal reforming step (d) in one or more water gas shift reactions; (f) removing the carbon dioxide from the water gas shift treated process gas stream; and (g) purifying the process gas stream from step (f); and (h) obtaining the ammonia synthesis gas, wherein at least a part of the hydrogen stream obtained in step (b)is added to process gas stream after step (g)in an amount to provide a molar ratio of the hydrogen to the nitrogen of 2.7-3.3 in the ammonia synthesis gas.
A control device for a construction machine, the control device comprising: an electronic joystick configured to generate a request signal for operation of a working device; a main controller configured to receive the request signal and generate a torque command and a pilot signal; an engine control unit configured to receive the torque command and generate an engine revolutions-per-minute (RPM) command; an engine configured to be operated in compliance with the engine RPM command; a hydraulic motor/pump configured to be operated by the engine and discharge a working fluid or to be driven by an entering working fluid and output power; an auxiliary power device additionally installed on the engine or hydraulic motor/pump , and configured to provide auxiliary power to the engine or hydraulic motor/pump ; and an engine load device including an air conditioner compressor powered by the engine ; characterized in that when the auxiliary power is provided from the auxiliary power device , the main controller or the engine control unit controls the engine RPM of the engine to be lowered to a first engine RPM adapted for the maintenance of the engine in an ON state. an electronic joystick configured to generate a request signal for operation of a working device; a main controller configured to receive the request signal and generate a torque command and a pilot signal; an engine control unit configured to receive the torque command and generate an engine revolutions-per-minute (RPM) command; an engine configured to be operated in compliance with the engine RPM command; a hydraulic motor/pump configured to be operated by the engine and discharge a working fluid or to be driven by an entering working fluid and output power; an auxiliary power device additionally installed on the engine or hydraulic motor/pump , and configured to provide auxiliary power to the engine or hydraulic motor/pump ; and an engine load device including an air conditioner compressor powered by the engine ;
A switching device for conducting and disconnecting electrical currents having - a first mechanical contact arrangement , - a second mechanical contact arrangement connected in series with the first mechanical contact arrangement, - a semiconductor switch connected in parallel to the first mechanical contact arrangement, and - a switching electronic system which is designed for switching the semiconductor switch on and off, - wherein the switching device is designed such that during a switching operation the two mechanical contact arrangements are closed with a time delay relative to one another, - a control circuit which is designed to determine a voltage across the first mechanical contact arrangement and, depending on the determined voltage, to generate a control signal for the switching electronic system which switches on the semiconductor switch characterized in that - the control circuit has a switch and a low-pass filter connected upstream thereof, wherein the switch generates the control signal for the switching electronic system . - a first mechanical contact arrangement , - a second mechanical contact arrangement connected in series with the first mechanical contact arrangement, - a semiconductor switch connected in parallel to the first mechanical contact arrangement, and - a switching electronic system which is designed for switching the semiconductor switch on and off, - wherein the switching device is designed such that during a switching operation the two mechanical contact arrangements are closed with a time delay relative to one another, - a control circuit which is designed to determine a voltage across the first mechanical contact arrangement and, depending on the determined voltage, to generate a control signal for the switching electronic system which switches on the semiconductor switch - the control circuit has a switch and a low-pass filter connected upstream thereof, wherein the switch generates the control signal for the switching electronic system .
A compound represented by the following formula I, an optical isomer thereof or a pharmaceutically acceptable salt thereof: Wherein, X is a Heterocycloalkyl selected from the group consisting of {wherein Z and W are each independently C or N, at least one of Z and W is N, a, b, c and d are each independently 1, 2 or 3, and R 3 , R 4 , R 5 and R 6 are each independently -H or -C 1 -C 4 alkyl}; Y is C or N; A and B are each independently -C 1 -C 4 alkyl, -C 6 -C 10 aryl, -C 3 -C 12 heteroaryl, -C 3 -C 10 cycloalkyl, -C 2 -C 10 heterocycloalkyl, or -C 3 -C 10 cycloalkenyl {wherein one or more hydrogen atoms of the -C 1 -C 4 alkyl may be substituted with -OH or halogen, and the -C 6 -C 10 aryl, -C 3 -C 12 heteroaryl, -C 3 -C 10 cycloalkyl, -C 2 -C 10 heterocycloalkyl and -C 3 -C 10 cycloalkenyl may be each independently unsubstituted or substituted with -OH, -C 1 -C 4 alkyl, -OC 1 -C 4 alkyl, -CF 3 or halogen at one or more hydrogen atoms thereof}; Q is C=O or SO 2 ; R 1 is -H or -C 1 -C 4 alkyl; R 2 is -H, -OH, -C 1 -C 4 alkyl, -C 1 -C 4 alkylhydroxy, halogen or null {provided that when Y is C, R 2 is -H, -OH, -C 1 -C 4 alkyl or -C 1 -C 4 alkylhydroxy, and when Y is N, R 2 is null}; and n is 1, 2, 3 or 4. X is a Heterocycloalkyl selected from the group consisting of {wherein Z and W are each independently C or N, at least one of Z and W is N, a, b, c and d are each independently 1, 2 or 3, and R 3 , R 4 , R 5 and R 6 are each independently -H or -C 1 -C 4 alkyl}; Y is C or N; A and B are each independently -C 1 -C 4 alkyl, -C 6 -C 10 aryl, -C 3 -C 12 heteroaryl, -C 3 -C 10 cycloalkyl, -C 2 -C 10 heterocycloalkyl, or -C 3 -C 10 cycloalkenyl {wherein one or more hydrogen atoms of the -C 1 -C 4 alkyl may be substituted with -OH or halogen, and the -C 6 -C 10 aryl, -C 3 -C 12 heteroaryl, -C 3 -C 10 cycloalkyl, -C 2 -C 10 heterocycloalkyl and -C 3 -C 10 cycloalkenyl may be each independently unsubstituted or substituted with -OH, -C 1 -C 4 alkyl, -OC 1 -C 4 alkyl, -CF 3 or halogen at one or more hydrogen atoms thereof}; Q is C=O or SO 2 ; R 1 is -H or -C 1 -C 4 alkyl; R 2 is -H, -OH, -C 1 -C 4 alkyl, -C 1 -C 4 alkylhydroxy, halogen or null {provided that when Y is C, R 2 is -H, -OH, -C 1 -C 4 alkyl or -C 1 -C 4 alkylhydroxy, and when Y is N, R 2 is null}; and n is 1, 2, 3 or 4.
A method, comprising: forming two vertical transport field effect transistors stacked one atop the other and separated by a two resistive random access memory structure, wherein the two vertical transport field effect transistors comprise a source , a channel , and a drain, wherein a contact layer of the resistive random access memory structure functions as the drain of the two vertical transport field effect transistors, characterized in that the two resistive random access memory structure includes a faceted epitaxy defined by pointed tips, wherein the pointed tips of the faceted epitaxy extend vertically toward each other.
A Claus burner having a pit vapor pipe and allowing a combustion reaction to be generated by reacting acid gas with oxygen in combustion air, the Claus burner comprising: a combustion air space part having a pit vapor inlet, a combustion air inlet, and a fuel inlet; a pit vapor pipe extending from the pit vapor inlet to an inside of the combustion air space part; and an acid gas space part having an acid gas inlet and a mixed gas outlet and being in fluid communication with the combustion air space part, wherein, the mixed gas comprises combustion air, pit vapor, and acid gas, and at an end of the pit vapor pipe, at least one part selected from a group consisting of an elbow, a deflector, and a plurality of slits is formed in order to spray the pit vapor into the combustion air space part. a combustion air space part having a pit vapor inlet, a combustion air inlet, and a fuel inlet; a pit vapor pipe extending from the pit vapor inlet to an inside of the combustion air space part; and an acid gas space part having an acid gas inlet and a mixed gas outlet and being in fluid communication with the combustion air space part, wherein, the mixed gas comprises combustion air, pit vapor, and acid gas, and at an end of the pit vapor pipe, at least one part selected from a group consisting of an elbow, a deflector, and a plurality of slits is formed in order to spray the pit vapor into the combustion air space part.