mhurhangee/patent-ind-claim-en huggingface dataset:
An implantable device comprising: a body, the body defining a designed surface topography of bone-contacting features and being sized for placement into an intravertebral disc space, the designed surface topography having a defined, repeating, three-dimensional pattern, the three dimensional pattern resulting from the application to the surface of first and second two-dimensional dimple surface patterns; each said first and second patterns having a depth dimension, the first said pattern depth dimension being greater than the second depth dimension to create a surface area of bone-contacting features that allow for in-growth and biological attachment to a biocompatible material, the body having a top surface , a bottom surface , opposing lateral sides , and opposing anterior and posterior portions. wherein the designed surface topography is provided on at least a portion of the top surface , the bottom surface , or both the top and bottom surfaces , and being produced by overlapping several features, wherein the designed surface topography on the top surface in the anterior portion has larger and sharper features, while the designed surface topography on the top surface in the posterior portion has smaller and less sharp features, the designed surface topography allowing for initial stabilization and long-term bone in-growth and fusion. a body, the body defining a designed surface topography of bone-contacting features and being sized for placement into an intravertebral disc space, the designed surface topography having a defined, repeating, three-dimensional pattern, the three dimensional pattern resulting from the application to the surface of first and second two-dimensional dimple surface patterns; each said first and second patterns having a depth dimension, the first said pattern depth dimension being greater than the second depth dimension to create a surface area of bone-contacting features that allow for in-growth and biological attachment to a biocompatible material, the body having a top surface , a bottom surface , opposing lateral sides , and opposing anterior and posterior portions. wherein the designed surface topography is provided on at least a portion of the top surface , the bottom surface , or both the top and bottom surfaces , and being produced by overlapping several features, wherein the designed surface topography on the top surface in the anterior portion has larger and sharper features, while the designed surface topography on the top surface in the posterior portion has smaller and less sharp features, the designed surface topography allowing for initial stabilization and long-term bone in-growth and fusion.
A fusion polypeptide, comprising an arginine deiminase (ADI) that is covalently linked to a Tumor Necrosis Factor (TNF) superfamily ligand, wherein the TNF superfamily ligand is a TNF-related apoptosis-inducing ligand (TRAIL) polypeptide, and wherein the ADI comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to any one of SEQ ID NOs: 9, 37, 38, 50, and 57-68, and wherein the TRAIL polypeptide comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to a sequence selected from SEQ ID NO: 70 and 69, and wherein the fusion polypeptide forms a hexameric complex of six ADI-TRAIL and/or TRAIL-ADI fusion polypeptides. wherein the TNF superfamily ligand is a TNF-related apoptosis-inducing ligand (TRAIL) polypeptide, and wherein the ADI comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to any one of SEQ ID NOs: 9, 37, 38, 50, and 57-68, and wherein the TRAIL polypeptide comprises, consists, or consists essentially of an amino acid sequence that is at least 98%, or 99% identical to a sequence selected from SEQ ID NO: 70 and 69, and wherein the fusion polypeptide forms a hexameric complex of six ADI-TRAIL and/or TRAIL-ADI fusion polypeptides.
Illuminating device comprising - a substrate , - a non-transparent spacer connected to the substrate in a hermetically sealed manner, - an opening in the spacer opposite to the substrate , and - a lighting element located below the spacer and below the opening, wherein electrical connections of the lighting element are passed through the substrate in a hermetically sealed manner, wherein the opening of the spacer is closed in a hermetically sealed manner with an optical element made of a glass material, the volume of which comprises at least one luminescent substance and as such is a luminescent glass composite material, characterized in that the glass composite material contains filling materials for adjusting a viscosity of a glass matrix during production of the illuminating device . - a substrate , - a non-transparent spacer connected to the substrate in a hermetically sealed manner, - an opening in the spacer opposite to the substrate , and - a lighting element located below the spacer and below the opening, wherein electrical connections of the lighting element are passed through the substrate in a hermetically sealed manner,
A task resource scheduling method, comprising: determining priority levels and set task deadline times of multiple tasks; determining a preset resource upper bound for a computing cluster executing the multiple tasks; and scheduling a successive order of executing the multiple tasks based on the task priority levels and a comparison between the preset resource upper bound and a sum of the amount of resources of the computing cluster being occupied by each overlapping task in a section on a time series where more than one task overlaps, so that the scheduled tasks satisfy a first condition, the first condition being that a time resource conflict does not exist between tasks, the time resource conflict being that a section exists on a time series where more than one task overlaps, and a sum of the resources occupied in the section having the overlap is greater than the resource upper bound. determining priority levels and set task deadline times of multiple tasks; determining a preset resource upper bound for a computing cluster executing the multiple tasks; and scheduling a successive order of executing the multiple tasks based on the task priority levels and a comparison between the preset resource upper bound and a sum of the amount of resources of the computing cluster being occupied by each overlapping task in a section on a time series where more than one task overlaps, so that the scheduled tasks satisfy a first condition, the first condition being that a time resource conflict does not exist between tasks, the time resource conflict being that a section exists on a time series where more than one task overlaps, and a sum of the resources occupied in the section having the overlap is greater than the resource upper bound.
An injection device for an injectable solution (S), including: - a containment tubular body , closed at the front by a closing element and at the back by a grasping portion , inside which at least one containment chamber is defined; - a dosing reservoir suitable to contain a fraction of the injectable solution (S), and having an inlet opening in communication with the containment chamber and an outlet opening ; - at least one plug arranged inside the tubular body in order to delimit the containment chamber , said plug being suitable to slide inside the tubular body and including a projecting appendix suitable to pass through the inlet opening of the dosing reservoir and to enter inside the latter in order to eject said fraction of solution from the dosing reservoir ; - a vent outlet , provided with a vent channel , suitable to be passed through by a second fraction of solution to eject the second fraction and to allow the projecting appendix to pass through the inlet opening of the dosing reservoir ; characterized by including an accessory having a storing cannula being engageable with the vent opening , and provided with a first end and a second end between which a storing reservoir for the second fraction of solution is defined, wherein the cross-section of the storing cannula is such to retain the second fraction of solution by capillarity inside the storing reservoir . - a containment tubular body , closed at the front by a closing element and at the back by a grasping portion , inside which at least one containment chamber is defined; - a dosing reservoir suitable to contain a fraction of the injectable solution (S), and having an inlet opening in communication with the containment chamber and an outlet opening ; - at least one plug arranged inside the tubular body in order to delimit the containment chamber , said plug being suitable to slide inside the tubular body and including a projecting appendix suitable to pass through the inlet opening of the dosing reservoir and to enter inside the latter in order to eject said fraction of solution from the dosing reservoir ; - a vent outlet , provided with a vent channel , suitable to be passed through by a second fraction of solution to eject the second fraction and to allow the projecting appendix to pass through the inlet opening of the dosing reservoir ;
A heat exchanger comprising: a first heat exchanger provided in the form of a plate, the first heat exchanger including a plurality of first heat exchange elements , both ends of the first heat exchanger each having the shape of a staircase in which corners and planes are alternately formed; and a second heat exchanger provided in the form of a plate and arranged to be inclined to the first heat exchanger , the second heat exchanger including a plurality of second heat exchange elements , the ends of the second heat exchanger have the shape of a staircase in which corners and planes are alternately formed, wherein a corner of the end of at least one of the plurality of first heat exchange elements of the first heat exchanger is positioned to face a plane of the end of the plurality of second heat exchange elements of the second heat exchanger , and a corner of the end of at least one of the plurality of second heat exchange elements of the second heat exchanger is positioned to face a plane of the plurality of first heat exchange elements of the first heat exchanger , the first heat exchanger includes a first staircase-shaped end formed by ends of the plurality of first heat exchange elements , the plurality of first heat exchange elements are provided in the form of plates and layered to overlay along a face plane direction. a first heat exchanger provided in the form of a plate, the first heat exchanger including a plurality of first heat exchange elements , both ends of the first heat exchanger each having the shape of a staircase in which corners and planes are alternately formed; and a second heat exchanger provided in the form of a plate and arranged to be inclined to the first heat exchanger , the second heat exchanger including a plurality of second heat exchange elements , the ends of the second heat exchanger have the shape of a staircase in which corners and planes are alternately formed, wherein a corner of the end of at least one of the plurality of first heat exchange elements of the first heat exchanger is positioned to face a plane of the end of the plurality of second heat exchange elements of the second heat exchanger , and a corner of the end of at least one of the plurality of second heat exchange elements of the second heat exchanger is positioned to face a plane of the plurality of first heat exchange elements of the first heat exchanger , the first heat exchanger includes a first staircase-shaped end formed by ends of the plurality of first heat exchange elements , the plurality of first heat exchange elements are provided in the form of plates and layered to overlay along a face plane direction.
A fastening jig suitable for securing a rare earth sintered magnet block as workpiece in a method for multiple cutoff machining the magnet block using a multiple blade assembly to machine the magnet block at a work surface thereof and cut it into multiple pieces, the fastening jig comprising a first clamp member and a second clamp member each having a workpiece-engaging face, for engaging respective opposite surfaces of said magnet block to clamp it between them in use, with sides of the clamp members positioned to correspond to respective opposite work surfaces of the magnet block, and a press unit for pressing the first and second clamp members to apply a pressing force to hold the magnet block between the first and second clamp members, and wherein a portion of at least one of said clamp members having said workpiece-engaging face is provided with a resilient cantilever portion by means of a channel extending inward behind said workpiece-engaging face from a said side of the clamp member , whereby the magnet block is held between the first and second clamp members against the resilient repulsion force created by the movement of the resilient cantilever portion.
Housing for a scanning optoelectronic measuring device, in particular laser scanner for a motor vehicle, having a window cap with a window transparent to electromagnetic measurement beams of the measuring device and with an edge wall formed at an angle to the window and forming an encircling contour, wherein the window cap has a window heater with heating loops for heating the transparent window , is pushed onto the outside of an encircling window edge of the housing and is fastened in a portion of the edge wall overlapping the window edge , characterized in that the housing has contact springs for contact-connecting conductor tracks of the heating loops to an electrical power supply of the heating device.
A plastic film, including: a supporting substrate; a first coating layer which is formed on one side of the supporting substrate; and a second coating layer which is formed on another side of the supporting substrate, wherein a first and a second coating layers include a crosslinking copolymer of a 3- to 6-functional acrylate compound and a thiol-containing compound, and inorganic particles independently equally or differently, and the plastic film shows a pencil hardness of 7H or more measured according to the Japanese Standard JIS K 5400 at the load of 1 kg, wherein the thicknesses of the first coating layer and the second coating layer is 50 to 150 μ m independently equally or differently. a supporting substrate; a first coating layer which is formed on one side of the supporting substrate; and a second coating layer which is formed on another side of the supporting substrate, wherein a first and a second coating layers include a crosslinking copolymer of a 3- to 6-functional acrylate compound and a thiol-containing compound, and inorganic particles independently equally or differently, and the plastic film shows a pencil hardness of 7H or more measured according to the Japanese Standard JIS K 5400 at the load of 1 kg, wherein the thicknesses of the first coating layer and the second coating layer is 50 to 150 μ m independently equally or differently.
A speech encoding apparatus comprising: a first encoding section for generating, from a speech signal (S11), first encoded information (S12) by CELP scheme speech encoding; a generating section for generating, as a parameter (S13) representing a feature of a generation model of the speech signal (S11), a quantized LSP, Line Spectral Pairs, from the first encoded information (S12); and a second encoding section for taking the speech signal as an input and encoding the inputted speech signal (S11) by CELP scheme speech encoding using the parameter (S13), and generating second encoded information (S14), wherein the second encoding section is further adapted to encode a difference between an LSP obtained by a linear prediction analysis on the speech signal (S11) and a quantized LSP generated by the generating section . a first encoding section for generating, from a speech signal (S11), first encoded information (S12) by CELP scheme speech encoding; a generating section for generating, as a parameter (S13) representing a feature of a generation model of the speech signal (S11), a quantized LSP, Line Spectral Pairs, from the first encoded information (S12); and a second encoding section for taking the speech signal as an input and encoding the inputted speech signal (S11) by CELP scheme speech encoding using the parameter (S13), and generating second encoded information (S14), wherein the second encoding section is further adapted to encode a difference between an LSP obtained by a linear prediction analysis on the speech signal (S11) and a quantized LSP generated by the generating section .
Vehicle comprising a tailgate pivotingly mounted between a closed position in which it closes a rear luggage compartment of said vehicle and an open position in which it gives access to said rear luggage compartment , said tailgate including a panel and a shell forming an internal lining of said tailgate and which is fastened to said panel , a storage area extending along a transverse axis Y of the vehicle is formed in the shell and closed off by the panel , characterized in that each of the two ends of said storage area , considered along said transverse axis Y, opens on the outside of said shell .
A guide for treating a knee joint of a patient, the guide comprising: a first portion , the first portion including at least one surface having a shape based, at least in part, on patient-specific information regarding a portion of a skin surface of the patient adjacent to the joint, so as to conform to said portion of a skin surface; and a second portion, the second portion comprising: a first surface shaped, at least in part, to conform to an anterior-facing portion of the tibial head of the patient; a second surface shaped, at least in part, to conform to the corresponding subchondral bone surface of the proximal tibia of the patient; and a guiding formation configured to guide a surgical instrument, the guiding formation having a predetermined position and orientation with respect to the at least one surface of the first portion and the first and second surface of the second portion. a first portion , the first portion including at least one surface having a shape based, at least in part, on patient-specific information regarding a portion of a skin surface of the patient adjacent to the joint, so as to conform to said portion of a skin surface; and a second portion, the second portion comprising: a first surface shaped, at least in part, to conform to an anterior-facing portion of the tibial head of the patient; a second surface shaped, at least in part, to conform to the corresponding subchondral bone surface of the proximal tibia of the patient; and a guiding formation configured to guide a surgical instrument, the guiding formation having a predetermined position and orientation with respect to the at least one surface of the first portion and the first and second surface of the second portion. a first surface shaped, at least in part, to conform to an anterior-facing portion of the tibial head of the patient; a second surface shaped, at least in part, to conform to the corresponding subchondral bone surface of the proximal tibia of the patient; and a guiding formation configured to guide a surgical instrument, the guiding formation having a predetermined position and orientation with respect to the at least one surface of the first portion and the first and second surface of the second portion.
An ophthalmic lens , comprising: an optic comprising an anterior surface , a posterior surface , and an optical axis , at least one of the anterior surface and the posterior surface comprising: a first zone extending from the optical axis to a first radial boundary; and a second zone extending from the first radial boundary to the edge of the optic; wherein: the first zone comprises an inner region and an outer region having a first curvature; and a phase shift feature separating the inner region and the outer region, the phase shift feature comprising a ridge extending outwardly from the inner region and the outer region , the ridge comprising a first phase shift step (Δ 1 ) extending outwardly from the inner region, and a second phase shift step (Δ 2 ) extending outwardly from the outer region. an optic comprising an anterior surface , a posterior surface , and an optical axis , at least one of the anterior surface and the posterior surface comprising: a first zone extending from the optical axis to a first radial boundary; and a second zone extending from the first radial boundary to the edge of the optic; a first zone extending from the optical axis to a first radial boundary; and a second zone extending from the first radial boundary to the edge of the optic; wherein: the first zone comprises an inner region and an outer region having a first curvature; and a phase shift feature separating the inner region and the outer region, the phase shift feature comprising a ridge extending outwardly from the inner region and the outer region , the ridge comprising a first phase shift step (Δ 1 ) extending outwardly from the inner region, and a second phase shift step (Δ 2 ) extending outwardly from the outer region. the first zone comprises an inner region and an outer region having a first curvature; and a phase shift feature separating the inner region and the outer region, the phase shift feature comprising a ridge extending outwardly from the inner region and the outer region , the ridge comprising a first phase shift step (Δ 1 ) extending outwardly from the inner region, and a second phase shift step (Δ 2 ) extending outwardly from the outer region.
Ophthalmic system comprising a variable-transmittance device including at least: - one battery, - one variable-transmittance lens and - one control circuit comprising at least one sensor suitable for measuring an ambient light level (E) periodically, the control circuit being suitable for automatically setting the transmittance value of the variable-transmittance lens depending on the light level (E) measured by the sensor , wherein the control circuit is suitable for: - defining at least three successive light-level plateaus (P), each light-level plateau (P) being bounded by a minimum light-level value (Emin) and a maximum light-level value (Emax), and being associated with one transmittance setpoint value of the lens, - determining the operational plateau in which the measured light-level value is located and then automatically commanding the transmittance setpoint value of the lens corresponding to the determined operational plateau, the control circuit being suitable for using a merit function depending on a plurality of criteria to define the successive light-level plateaus so as to define a large number of operational plateaus when the battery is completely charged and a lower number of operational plateaus when the battery is discharged in order to decrease the electrical power consumption of the device. - one battery, - one variable-transmittance lens and - one control circuit comprising at least one sensor suitable for measuring an ambient light level (E) periodically, the control circuit being suitable for automatically setting the transmittance value of the variable-transmittance lens depending on the light level (E) measured by the sensor , - defining at least three successive light-level plateaus (P), each light-level plateau (P) being bounded by a minimum light-level value (Emin) and a maximum light-level value (Emax), and being associated with one transmittance setpoint value of the lens, - determining the operational plateau in which the measured light-level value is located and then automatically commanding the transmittance setpoint value of the lens corresponding to the determined operational plateau,