mhurhangee/patent-ind-claim-en huggingface dataset:
An in vitro method of diagnosing hormone refractory prostate cancer on the basis of a biomarker being a protein or a polynucleotide having an alteration in the expression level or activity that is associated with hormone refractory prostate cancer, the method comprising: (i) determining the level of expression of a nucleic acid having a sequence that is or is complementary to androgen receptor (AR) gene variant having SEQ ID NO:1 (AR-V7) or a sequence being at least 90%, 95% or 99% identical thereto in a sample taken from a subject, or; (ii) determining the level of expression of a polypeptide having an amino acid sequence encoded by an androgen receptor (AR) gene variant having SEQ ID NO:8 (AR-V7) or a sequence being at least 90%, 95% or 99% identical thereto in a sample taken from a subject, wherein an increased level of expression relative to a reference selected from a control subject sample or a subject sample obtained at an earlier time point is indicative of hormone refractory prostate cancer. (i) determining the level of expression of a nucleic acid having a sequence that is or is complementary to androgen receptor (AR) gene variant having SEQ ID NO:1 (AR-V7) or a sequence being at least 90%, 95% or 99% identical thereto in a sample taken from a subject, or; (ii) determining the level of expression of a polypeptide having an amino acid sequence encoded by an androgen receptor (AR) gene variant having SEQ ID NO:8 (AR-V7) or a sequence being at least 90%, 95% or 99% identical thereto in a sample taken from a subject, wherein an increased level of expression relative to a reference selected from a control subject sample or a subject sample obtained at an earlier time point is indicative of hormone refractory prostate cancer.
Layer system for thin film solar cells , comprising: - an absorber layer , which contains a chalcogenide compound semiconductor and - a buffer layer , which is arranged on the absorber layer and contains halogen-enriched In x S y with 2/3 ≤ x/y ≤ 1, wherein elements of the buffer layer other than indium, sulphur, the metal of a metal halide compound and the halogen are present in a proportion of less than or equal to 5 mol%, wherein the buffer layer consists of a first layer region (5.1) with a halogen molar fraction A 1 adjacent to the absorber layer and a second layer region (5.2) with a halogen molar fraction A 2 adjacent to the first layer region (5.1), and the ratio A 1 /A 2 is from 9 to 1000, and the layer thickness (d 1 ) of the first layer region (5.1) is ≤ 50% of the layer thickness (d) of the buffer layer , wherein the amount of halogen in the first layer region (5.1) corresponds to an occupancy area of 1·10 13 atoms/cm 2 to 1·10 17 atoms/cm 2 , and wherein the halogen molar fraction in the buffer layer has a gradient which falls from a surface facing the absorber layer to the interior of the buffer layer . - an absorber layer , which contains a chalcogenide compound semiconductor and - a buffer layer , which is arranged on the absorber layer and contains halogen-enriched In x S y with 2/3 ≤ x/y ≤ 1, wherein elements of the buffer layer other than indium, sulphur, the metal of a metal halide compound and the halogen are present in a proportion of less than or equal to 5 mol%, wherein the buffer layer consists of a first layer region (5.1) with a halogen molar fraction A 1 adjacent to the absorber layer and a second layer region (5.2) with a halogen molar fraction A 2 adjacent to the first layer region (5.1), and the ratio A 1 /A 2 is from 9 to 1000, and the layer thickness (d 1 ) of the first layer region (5.1) is ≤ 50% of the layer thickness (d) of the buffer layer , wherein the amount of halogen in the first layer region (5.1) corresponds to an occupancy area of 1·10 13 atoms/cm 2 to 1·10 17 atoms/cm 2 , and wherein the halogen molar fraction in the buffer layer has a gradient which falls from a surface facing the absorber layer to the interior of the buffer layer .
A method comprising: executing , by a processor of a computing device , at least a portion of an application that includes a plurality of tabs , each tab associated with a respective document that is configured to be rendered for display by the application; determining if a particular tab of the plurality of tabs is permitted to record an audio and/or visual signal; and upon determining the particular tab of the plurality of tabs has been granted permission to and the application is capturing the audio and/or visual signal derived from an environment of the computing device, providing a graphical indication, associated with the particular tab and visible when the particular tab is in focus as well as when it is not in focus, that indicates to a user of the computing device that the particular tab is capturing the audio and/or visual signal, wherein providing the graphical indication associated with the particular tab includes: displaying the graphical indication within a notification center associated with an operating system executed by the processor of the computing device when a label handle for the particular tab is hidden; or displaying the graphical indication within a central or common area of the application when a label handle for the particular tab is hidden. executing , by a processor of a computing device , at least a portion of an application that includes a plurality of tabs , each tab associated with a respective document that is configured to be rendered for display by the application; determining if a particular tab of the plurality of tabs is permitted to record an audio and/or visual signal; and upon determining the particular tab of the plurality of tabs has been granted permission to and the application is capturing the audio and/or visual signal derived from an environment of the computing device, providing a graphical indication, associated with the particular tab and visible when the particular tab is in focus as well as when it is not in focus, that indicates to a user of the computing device that the particular tab is capturing the audio and/or visual signal, wherein providing the graphical indication associated with the particular tab includes: displaying the graphical indication within a notification center associated with an operating system executed by the processor of the computing device when a label handle for the particular tab is hidden; or displaying the graphical indication within a central or common area of the application when a label handle for the particular tab is hidden. displaying the graphical indication within a notification center associated with an operating system executed by the processor of the computing device when a label handle for the particular tab is hidden; or displaying the graphical indication within a central or common area of the application when a label handle for the particular tab is hidden.
A method of processing an image based on inter-prediction, comprising steps of: obtaining a first motion vector of a current block to which uni-directional inter-prediction using a single reference picture is applied, the first motion vector indicating a first reference block (A) in a first reference picture , obtaining a second motion vector of the first reference block, the second motion vector indicating a second reference block in a second reference picture ; determining a scale factor based on a ratio of a difference between a Picture Order Count, POC, of a current picture including the current block and a POC of the first reference picture and a difference between a POC of the current picture and the POC of the second reference picture; determining a scaled motion vector for each pixel within the current block to minimize a square of a pixel value difference of two corresponding pixels respectively included in the first and second reference blocks by using an optical flow method in consideration of the scale factor; deriving a predictor for the each pixel within the current block based on the scaled motion vector. obtaining a first motion vector of a current block to which uni-directional inter-prediction using a single reference picture is applied, the first motion vector indicating a first reference block (A) in a first reference picture , obtaining a second motion vector of the first reference block, the second motion vector indicating a second reference block in a second reference picture ; determining a scale factor based on a ratio of a difference between a Picture Order Count, POC, of a current picture including the current block and a POC of the first reference picture and a difference between a POC of the current picture and the POC of the second reference picture; determining a scaled motion vector for each pixel within the current block to minimize a square of a pixel value difference of two corresponding pixels respectively included in the first and second reference blocks by using an optical flow method in consideration of the scale factor; deriving a predictor for the each pixel within the current block based on the scaled motion vector.
A method of detecting alpha-synuclein phosphorylated at serine 129 (PS129 alpha-synuclein), comprising: (a) contacting a sample with a capture antibody that specifically binds to an epitope within residues 124-134 of PS129 alpha-synuclein and a reporter antibody that specifically binds to an epitope within residues 40-55 of alpha-synuclein; wherein if PS129 alpha-synuclein is present in the sample, the capture antibody and reporter antibody bind to the PS129 alpha-synuclein forming a sandwich complex; and (b) detecting the reporter antibody that binds to the PS129-alpha synuclein in step (a), if any, to indicate presence or absence of the PS129 alpha-synuclein. (a) contacting a sample with a capture antibody that specifically binds to an epitope within residues 124-134 of PS129 alpha-synuclein and a reporter antibody that specifically binds to an epitope within residues 40-55 of alpha-synuclein; wherein if PS129 alpha-synuclein is present in the sample, the capture antibody and reporter antibody bind to the PS129 alpha-synuclein forming a sandwich complex; and (b) detecting the reporter antibody that binds to the PS129-alpha synuclein in step (a), if any, to indicate presence or absence of the PS129 alpha-synuclein.
A system-on-chip contactless physiological sensor comprising: a capacitive-sensor electrode having a first capacitance (C1); an amplifier device connected to the capacitive-sensor electrode , the amplifier device having an inverting input (-) and a non-inverting input (+), the capacitive-sensor electrode and the amplifier device at least in part forming an amplifier circuit for the physiological sensor which has a gain determined by the values of a third capacitance (C3) of a bridging capacitor which spans the amplifier device between the inverting input (-) and an output of the amplifier device and a capacitance (C2) of an artefact-reducing capacitor ; wherein the artefact-reducing capacitor being connected in series between the capacitive-sensor electrode and an input of the amplifier device , wherein the second capacitance (C2) is less than the first capacitance (C1); wherein there is no impedance boosting input between the capacitive-sensor electrode and the inverting input (-) of the amplifier device , wherein the gain of the amplifier device is determined by the formula: gain = C 1 C 2 C 1 + C 2 C 3 = C 1 1 + C 2 C 1 C 3 ≅ C 2 C 3 where C1 is the first capacitance, C2 is the second capacitance, and C3 is the third capacitance. a capacitive-sensor electrode having a first capacitance (C1); an amplifier device connected to the capacitive-sensor electrode , the amplifier device having an inverting input (-) and a non-inverting input (+), the capacitive-sensor electrode and the amplifier device at least in part forming an amplifier circuit for the physiological sensor which has a gain determined by the values of a third capacitance (C3) of a bridging capacitor which spans the amplifier device between the inverting input (-) and an output of the amplifier device and a capacitance (C2) of an artefact-reducing capacitor ; wherein the artefact-reducing capacitor being connected in series between the capacitive-sensor electrode and an input of the amplifier device , wherein the second capacitance (C2) is less than the first capacitance (C1); wherein there is no impedance boosting input between the capacitive-sensor electrode and the inverting input (-) of the amplifier device , wherein the gain of the amplifier device is determined by the formula: gain = C 1 C 2 C 1 + C 2 C 3 = C 1 1 + C 2 C 1 C 3 ≅ C 2 C 3 where C1 is the first capacitance, C2 is the second capacitance, and C3 is the third capacitance.
A method for determining placement of a virtual serving gateway, the method comprising: obtaining a set of input information , the input information including: network information providing information about a physical network for mobile communications by a mobile device; and configuration information providing one or more parameters for placing the virtual serving gateway; determining placement of the virtual serving gateway at two or more physical hosts in the physical network in accordance with the network information and the configuration information, the virtual serving gateway being distributively placed across the two or more physical hosts, wherein a fraction of the virtual serving gateway is hosted by each physical host and a corresponding fraction of gateway traffic is served by each physical host; and generating a set of output information including: information identifying placement of the virtual serving gateway at the two or more physical hosts; and a respective hosting percentage for each physical host indicating a percentage of the gateway traffic served by each physical host. obtaining a set of input information , the input information including: network information providing information about a physical network for mobile communications by a mobile device; and configuration information providing one or more parameters for placing the virtual serving gateway; network information providing information about a physical network for mobile communications by a mobile device; and configuration information providing one or more parameters for placing the virtual serving gateway; determining placement of the virtual serving gateway at two or more physical hosts in the physical network in accordance with the network information and the configuration information, the virtual serving gateway being distributively placed across the two or more physical hosts, wherein a fraction of the virtual serving gateway is hosted by each physical host and a corresponding fraction of gateway traffic is served by each physical host; and generating a set of output information including: information identifying placement of the virtual serving gateway at the two or more physical hosts; and a respective hosting percentage for each physical host indicating a percentage of the gateway traffic served by each physical host. information identifying placement of the virtual serving gateway at the two or more physical hosts; and a respective hosting percentage for each physical host indicating a percentage of the gateway traffic served by each physical host.
A process kit for a plasma processing chamber , comprising: a conductive body having an orientation when the conductive body is in use in the plasma processing chamber such that a top of the conductive body and a vertical centerline are defined, the conductive body having an array of features formed in a surface of the conductive body that is exposed to a plasma when in use in the plasma processing chamber, the features having an opening in the surface, the features having a profile, the profile having a geometric centerline extending away from the top of the conductive body through the opening, the geometric centerline forming an obtuse angle with the vertical centerline of the conductive body, wherein the features are arranged in a downward facing orientation to create shadowed areas such that, in use, a significant portion of the shadowed areas remains deposition free and such that a ground return path for the plasma is maintained.
A filament refilling system for automatically loading into a 3-D printer extruder a refill filament to replace a first filament , the filament refilling system comprising: a filament guide configured to receive the first filament , receive the refill filament , and output received filaments to the extruder; and a preloading device (1100; 1200; 1400) configured to exert a first force on the refill filament in a direction towards the filament guide and the extruder, which first force, when exerted on the refill filament , causes the refill filament to automatically travel through the filament guide and into the extruder upon removal of a blocking force by the first filament , the filament guide being configured for the removal of the blocking force to occur upon depletion of the first filament . a filament guide configured to receive the first filament , receive the refill filament , and output received filaments to the extruder; and a preloading device (1100; 1200; 1400) configured to exert a first force on the refill filament in a direction towards the filament guide and the extruder, which first force, when exerted on the refill filament , causes the refill filament to automatically travel through the filament guide and into the extruder upon removal of a blocking force by the first filament , the filament guide being configured for the removal of the blocking force to occur upon depletion of the first filament .
Pallet truck comprising two forks for lifting and transporting a pallet, a hydraulic lifting system comprising a first hydraulic pump and a hydraulic cylinder , a tiller arm that is operable for powering the first hydraulic pump by a manual lifting an lowering movement of the tiller arm , such that a load is lifted by actuating of the hydraulic cylinder on the forks to a maximal height H and at a maximal weight M, further comprised are a main wheel that are hinged in a vertical axle to which they are attached, the tiller arm is connected to the wheels for steering them by rotating in the vertical axle , characterized in that the pallet truck comprises an electric motor and a second hydraulic pump powered by the electric motor , wherein the electric motor and the second hydraulic pump are operable to lift the forks to the maximal height h, wherein h < H, and/or wherein the electric motor and second hydraulic pump has a capacity to lift a maximal load of mass m, wherein m < M.
A medium or high voltage switchgear with a three position switch, characterized in that the three position switch comprises a tube shaped conductor for connection of a cable and the three position switch comprises an earthing contact , and wherein the earthing contact is arranged coaxial to the tube shaped conductor wherein the three position switch comprises a piston , and wherein the piston is configured to move axially within the tube shaped conductor; wherein in a connected position the piston is at a position axially within the tube shaped conductor configured to enable current to flow to the cable, wherein in the connected position the piston connects a busbar of the medium or high voltage switchgear to a cable contact of the tube shaped conductor for connection of the cable, thereby enabling current to flow from the busbar to the cable, and wherein in the connected position the piston is isolated from the earthing contact; wherein in an isolated position the piston is at a position axially within the tube shaped conductor such that current is not enabled to flow to the cable; and wherein in an earthed position the piston is at a position axially within the tube shaped conductor such that the piston connects the tube shaped conductor to the earthing contact, characterized in that the earthing contact is arranged inside the tube shaped conductor . the three position switch comprises a tube shaped conductor for connection of a cable and the three position switch comprises an earthing contact , and wherein the earthing contact is arranged coaxial to the tube shaped conductor wherein the three position switch comprises a piston , and wherein the piston is configured to move axially within the tube shaped conductor; wherein in a connected position the piston is at a position axially within the tube shaped conductor configured to enable current to flow to the cable, wherein in the connected position the piston connects a busbar of the medium or high voltage switchgear to a cable contact of the tube shaped conductor for connection of the cable, thereby enabling current to flow from the busbar to the cable, and wherein in the connected position the piston is isolated from the earthing contact; wherein in an isolated position the piston is at a position axially within the tube shaped conductor such that current is not enabled to flow to the cable; and wherein in an earthed position the piston is at a position axially within the tube shaped conductor such that the piston connects the tube shaped conductor to the earthing contact,
A data transmission method, comprising: receiving , by a terminal device, a plurality of indication information from a policy control function, PCF, network element, wherein each indication information comprises data network access identifier, DNAI, information corresponding to a respective application, wherein each application corresponds to an application function element included in a data network; and determining , by the terminal device based on each indication information, a packet data unit, PDU, session corresponding to each application for transmitting data of each application; characterised in that the determining comprises: transmitting, by the terminal device in a same PDU session, data of each application with a same DNAI information; and transmitting, by the terminal device in different PDU sessions, data of each application with different DNAI information. receiving , by a terminal device, a plurality of indication information from a policy control function, PCF, network element, wherein each indication information comprises data network access identifier, DNAI, information corresponding to a respective application, wherein each application corresponds to an application function element included in a data network; and determining , by the terminal device based on each indication information, a packet data unit, PDU, session corresponding to each application for transmitting data of each application; characterised in that the determining comprises: transmitting, by the terminal device in a same PDU session, data of each application with a same DNAI information; and transmitting, by the terminal device in different PDU sessions, data of each application with different DNAI information. transmitting, by the terminal device in a same PDU session, data of each application with a same DNAI information; and transmitting, by the terminal device in different PDU sessions, data of each application with different DNAI information.
Method for producing a vehicle component in the form of a chassis component for a motor vehicle, having the method steps of: introducing a fibre matrix semi-finished product with thermosetting matrix into a pressing mould, producing a bearing bushing by pressing the fibre matrix semi-finished product , producing a fibre preform for a connecting strut , introducing the fibre preform into a transfer mould, producing the connecting strut by impregnating the fibre preform with a thermosetting material, which is injected into the transfer mould for this purpose, and fixedly connecting the connecting strut to the bearing bushing , wherein the bearing bushing is produced with a connection region , and, for the purposes of fixedly connecting the connecting strut to the bearing bushing , an end region of the connecting strut is connected to the connection region of the bearing bushing in a positively-locking manner.