mhurhangee/patent-ind-claim-en huggingface dataset:
A method of preparing a stable liquid pharmaceutical formulation, comprising combining: (a) an antibody which binds specifically to human programmed death-1 (PD-1),wherein the antibody comprises three heavy chain complementarity determining regions (CDRs) (HCDR1, HCDR2 and HCDR3) contained in a heavy chain variable region (HCVR) and three light chain CDRs (LCDR1, LCDR2 and LCDR3) contained in a light chain variable region (LCVR), wherein HCDR1 comprises SEQ ID NO: 3, HCDR2 comprises SEQ ID NO: 4, HCDR3 comprises SEQ ID NO: 5, LCDR1 comprises SEQ ID NO: 6, LCDR2 comprises SEQ ID NO: 7, and LCDR3 comprises SEQ ID NO: 8; (b) a buffer comprising histidine; (c) an organic solvent comprising polysorbate; (d) sucrose as stabilizer; and (e) proline as viscosity modifier; wherein the stable liquid pharmaceutical formulation has a pH of 6.0 ± 0.3. (a) an antibody which binds specifically to human programmed death-1 (PD-1),wherein the antibody comprises three heavy chain complementarity determining regions (CDRs) (HCDR1, HCDR2 and HCDR3) contained in a heavy chain variable region (HCVR) and three light chain CDRs (LCDR1, LCDR2 and LCDR3) contained in a light chain variable region (LCVR), wherein HCDR1 comprises SEQ ID NO: 3, HCDR2 comprises SEQ ID NO: 4, HCDR3 comprises SEQ ID NO: 5, LCDR1 comprises SEQ ID NO: 6, LCDR2 comprises SEQ ID NO: 7, and LCDR3 comprises SEQ ID NO: 8; (b) a buffer comprising histidine; (c) an organic solvent comprising polysorbate; (d) sucrose as stabilizer; and (e) proline as viscosity modifier;
A socket comprising: a base member configured to hold a plurality of contacts ; a cover member configured to move in a direction to be close to or separated from the base member ; a latch member having a pressing portion located at a first end of the latch member , the pressing portion configured to press on an electronic device mounted on the socket ; a first link member , a first end of the first link member connected with the cover member , a second end of the first link member connected with the first end of the latch member ; and a first lever member rotatably fixed to the base member , a first end of the first lever member connected with the cover member , a second end of the first lever member connected with a second end of the latch member opposed to the first end of the latch member; wherein the first link member and the first lever member are configured to move the pressing portion of the latch member to an evacuated position when the cover member moves in a direction to be close to the base member , and the first link member and the first lever member are configured to move the pressing portion of the latch member to a position where the electronic device is pressed when the cover member moves in a direction to be separated from the base member . a base member configured to hold a plurality of contacts ; a cover member configured to move in a direction to be close to or separated from the base member ; a latch member having a pressing portion located at a first end of the latch member , the pressing portion configured to press on an electronic device mounted on the socket ; a first link member , a first end of the first link member connected with the cover member , a second end of the first link member connected with the first end of the latch member ; and a first lever member rotatably fixed to the base member , a first end of the first lever member connected with the cover member , a second end of the first lever member connected with a second end of the latch member opposed to the first end of the latch member; wherein the first link member and the first lever member are configured to move the pressing portion of the latch member to an evacuated position when the cover member moves in a direction to be close to the base member , and the first link member and the first lever member are configured to move the pressing portion of the latch member to a position where the electronic device is pressed when the cover member moves in a direction to be separated from the base member .
A yarn comprising: a fiber comprising an elastomeric propylene based polymer and an anti-tack agent, said fiber being substantially free of a silicone-based finish; wherein the fiber comprises 1% to 30% by weight of an anti-tack agent; wherein the anti-tack agent is a combination of a bis-stearamide and TiO 2 .
A communication system in which a vehicle including a power storage device and a power supply device configured to supply power to the power storage device are connected to each other via a power supply line used for power supply and a control line for transmitting a control signal required for control of the power supply using the power supply line , wherein at least one of the vehicle and the power supply device includes a transmission section , characterized in that the transmission section is configured to transmit a communication signal different from the control signal as an electric signal superposed on carriers using the control line as a medium, and the transmission section includes adjustment means configured to adjust an output waveform relating to the transmission of the communication signal to an amplitude previously set for each frequency based on crosstalk characteristics with respect to the power supply line .
A computer-implemented wrinkle detection method, wherein the method comprises: obtaining, by a terminal device, an original image, wherein the original image comprises a face; determining (S401), by the terminal device, a Region Of Interest, ROI, region on the original image, wherein the ROI region is a region in which a wrinkle on the face is located; segmenting (S402), by the terminal device, the ROI region from the original image to obtain an ROI image; scaling (S402), by the terminal device, the ROI image to obtain at least two ROI images of different sizes; processing (S403), by the terminal device, all the at least two ROI images of different sizes to obtain at least two binary images, wherein a white region in each binary image is a region in which the wrinkle is suspected to appear; and fusing (S404), by the terminal device, the at least two binary images to obtain a final image, wherein a white region on the final image is recognized as the wrinkle, wherein before the fusing, by the terminal device, the at least two binary images to obtain a final image, the method further comprises: if the terminal device determines that a number P of images of the at least two binary images that have a white region at a same position is less than or equal to a preset value M, deleting the white region at the position from the P images, wherein M is greater than or equal to 2. obtaining, by a terminal device, an original image, wherein the original image comprises a face; determining (S401), by the terminal device, a Region Of Interest, ROI, region on the original image, wherein the ROI region is a region in which a wrinkle on the face is located; segmenting (S402), by the terminal device, the ROI region from the original image to obtain an ROI image; scaling (S402), by the terminal device, the ROI image to obtain at least two ROI images of different sizes; processing (S403), by the terminal device, all the at least two ROI images of different sizes to obtain at least two binary images, wherein a white region in each binary image is a region in which the wrinkle is suspected to appear; and fusing (S404), by the terminal device, the at least two binary images to obtain a final image, wherein a white region on the final image is recognized as the wrinkle, wherein before the fusing, by the terminal device, the at least two binary images to obtain a final image, the method further comprises: if the terminal device determines that a number P of images of the at least two binary images that have a white region at a same position is less than or equal to a preset value M, deleting the white region at the position from the P images, wherein M is greater than or equal to 2.
A method of forming a multi-layer dosage form having at least two layers comprising: (a) dosing a first formulation comprising a first non-gelling matrix forming agent and having a first density into a preformed mold; (b) dosing a second formulation comprising a second non-gelling matrix forming agent and having a second density not equal to the first density into the same preformed mold, wherein a difference between the density of the first formulation and the density of the second formulation is 0.005 g/ml to 0.475 g/ml; (c) freezing the first and second dosed formulations; and (d) freeze drying the frozen first and second formulations to form the multi-layered dosage form having at least two layers. (a) dosing a first formulation comprising a first non-gelling matrix forming agent and having a first density into a preformed mold; (b) dosing a second formulation comprising a second non-gelling matrix forming agent and having a second density not equal to the first density into the same preformed mold, wherein a difference between the density of the first formulation and the density of the second formulation is 0.005 g/ml to 0.475 g/ml; (c) freezing the first and second dosed formulations; and (d) freeze drying the frozen first and second formulations to form the multi-layered dosage form having at least two layers.
A multi-aperture vacuum tool comprising: a distributed vacuum tool portion , the distributed vacuum tool portion comprised of a plate having a plurality of apertures that extend through an interior plate surface and an exterior plate surface , wherein air is able to pass through the plurality of apertures from the exterior plate surface towards the interior plate surface when the distributed vacuum tool portion is activated; and a refined vacuum tool portion , wherein the refined vacuum tool portion is physically coupled to the distributed vacuum tool portion , the refined vacuum tool portion has fewer apertures than the plurality of apertures of the distributed vacuum tool portion , the distributed vacuum tool portion is configured to manipulate a portion of material, the refined vacuum tool portion is configured to manipulate a smaller portion of material than the portion of material which the distributed vacuum tool portion manipulates, and characterized in that a material-contacting surface of the refined vacuum tool portion is in a common plane as the plate . a distributed vacuum tool portion , the distributed vacuum tool portion comprised of a plate having a plurality of apertures that extend through an interior plate surface and an exterior plate surface , wherein air is able to pass through the plurality of apertures from the exterior plate surface towards the interior plate surface when the distributed vacuum tool portion is activated; and a refined vacuum tool portion , wherein the refined vacuum tool portion is physically coupled to the distributed vacuum tool portion , the refined vacuum tool portion has fewer apertures than the plurality of apertures of the distributed vacuum tool portion , the distributed vacuum tool portion is configured to manipulate a portion of material, the refined vacuum tool portion is configured to manipulate a smaller portion of material than the portion of material which the distributed vacuum tool portion manipulates, and characterized in that a material-contacting surface of the refined vacuum tool portion is in a common plane as the plate .
A composite material comprising: • a resin, wherein the resin is a polyimide having a thermal conductivity; and • a plurality of passivated aluminum nitride particles substantially uniformly dispersed in the resin to provide the composite material with a thermal conductivity of 0.4 W/mK to 2.5 W/mK, wherein each of the plurality of passivated aluminum nitride particles comprises a passivation layer disposed over an aluminum nitride particle core to inhibit oxidation and thermal degradation of a surface of the aluminum nitride particle core; wherein the plurality of passivated aluminum nitride particles are present in an amount ranging from 0.01 weight % to 50 weight % of the total weight of the composite material. • a resin, wherein the resin is a polyimide having a thermal conductivity; and • a plurality of passivated aluminum nitride particles substantially uniformly dispersed in the resin to provide the composite material with a thermal conductivity of 0.4 W/mK to 2.5 W/mK,
A method for forming a vacuum in an X-ray tube assembly, the method comprising: providing the X-ray tube assembly defining an internal vacuum chamber in fluid communication with an exterior of the X-ray tube assembly via a conduit in the X-ray tube assembly between the vacuum chamber and the exterior of the X-ray tube assembly ; positioning a plug in the conduit to at least partially occlude the conduit such that at least one space between the plug and the X-ray tube assembly permits fluid to travel between the vacuum chamber and the exterior of the X-ray tube assembly ; evacuating the vacuum chamber so that gas in the vacuum chamber exits the vacuum chamber through the at least one space between the plug and the X-ray tube assembly ; respositioning the plug further into the conduit towards the vacuum chamber ; and sealing the evacuated vacuum chamber with the plug and conduit such that the vacuum chamber is sealed from the exterior of the X-ray tube assembly . providing the X-ray tube assembly defining an internal vacuum chamber in fluid communication with an exterior of the X-ray tube assembly via a conduit in the X-ray tube assembly between the vacuum chamber and the exterior of the X-ray tube assembly ; positioning a plug in the conduit to at least partially occlude the conduit such that at least one space between the plug and the X-ray tube assembly permits fluid to travel between the vacuum chamber and the exterior of the X-ray tube assembly ; evacuating the vacuum chamber so that gas in the vacuum chamber exits the vacuum chamber through the at least one space between the plug and the X-ray tube assembly ; respositioning the plug further into the conduit towards the vacuum chamber ; and sealing the evacuated vacuum chamber with the plug and conduit such that the vacuum chamber is sealed from the exterior of the X-ray tube assembly .
A touch sensor integrated type display device comprising: a plurality of data lines (DL1, ..., DLn) and a plurality of gate lines (GL1, ..., GLm) crossing over each other; a plurality of pixel electrodes (Px) to which data signals are supplied through the plurality of data lines (DL1, ..., DLn); and a touch electrode (Tx) configured to overlap the plurality of pixel electrodes (Px), wherein the touch sensor integrated type display device is configured to supply a touch driving signal (TSP) to the touch electrode (Tx) and then detect a touch position from sensing the touch electrode (Tx), characterized in that the display device is an electroluminescence display device and is configured to supply the touch driving signal (TSP) to the touch electrode (Tx) through the plurality of data lines (DL1, ..., DLn). a plurality of data lines (DL1, ..., DLn) and a plurality of gate lines (GL1, ..., GLm) crossing over each other; a plurality of pixel electrodes (Px) to which data signals are supplied through the plurality of data lines (DL1, ..., DLn); and a touch electrode (Tx) configured to overlap the plurality of pixel electrodes (Px), wherein the touch sensor integrated type display device is configured to supply a touch driving signal (TSP) to the touch electrode (Tx) and then detect a touch position from sensing the touch electrode (Tx), characterized in that the display device is an electroluminescence display device and is configured to supply the touch driving signal (TSP) to the touch electrode (Tx) through the plurality of data lines (DL1, ..., DLn).
A fiber draw furnace , comprising: a heated section configured to contain and heat a glass source from which an optical fiber is drawn; a lower extended muffle having a first end and a second end ; a gas screen coupled to the second end of the lower extended muffle configured to allow a gas to flow into the lower extended muffle ; and a reclaim cylinder coupled to the lower extended muffle , comprising: an outer housing defining a reclaim chamber , wherein a plurality of reclaim ports are tangentially coupled to the outer housing ; and an inner housing positioned within the outer housing ; characterised in that the reclaim cylinder is positioned between the first end of the lower extended muffle and the heated section . a heated section configured to contain and heat a glass source from which an optical fiber is drawn; a lower extended muffle having a first end and a second end ; a gas screen coupled to the second end of the lower extended muffle configured to allow a gas to flow into the lower extended muffle ; and a reclaim cylinder coupled to the lower extended muffle , comprising: an outer housing defining a reclaim chamber , wherein a plurality of reclaim ports are tangentially coupled to the outer housing ; and an inner housing positioned within the outer housing ; characterised in that the reclaim cylinder is positioned between the first end of the lower extended muffle and the heated section . an outer housing defining a reclaim chamber , wherein a plurality of reclaim ports are tangentially coupled to the outer housing ; and an inner housing positioned within the outer housing ; characterised in that the reclaim cylinder is positioned between the first end of the lower extended muffle and the heated section .
A cardiac device for creating a shunt in an atrial septum of a patient, comprising: a wire comprised of a shape memory alloy, wherein the wire is adapted to transform from a substantially straight wire to a coil shape upon heating or due to superelastic properties of the wire and wherein the wire, upon transforming to the coil shape, comprises at least two inner loops and at least two outer loops wherein a diameter of the at least two inner loops are each less than a diameter of each of the at least two outer loops, and wherein the wire, when in the coil shape, is adapted to exert a compressive force upon layers of tissue caught between the at least two inner loops; and characterized in that the device further comprises a plurality of magnets coupled to the at least two inner loops, wherein the plurality of magnets are adapted to provide a compressive force to adjacent inner loops of the wire in the coil shape, thereby further causing the wire or the magnets to cut through the layers of tissue and create a shunt of a diameter less than the diameter of the outer loops such that the at least two outer loops do not pass through said shunt. a wire comprised of a shape memory alloy, wherein the wire is adapted to transform from a substantially straight wire to a coil shape upon heating or due to superelastic properties of the wire and wherein the wire, upon transforming to the coil shape, comprises at least two inner loops and at least two outer loops wherein a diameter of the at least two inner loops are each less than a diameter of each of the at least two outer loops, and wherein the wire, when in the coil shape, is adapted to exert a compressive force upon layers of tissue caught between the at least two inner loops; and characterized in that the device further comprises a plurality of magnets coupled to the at least two inner loops, wherein the plurality of magnets are adapted to provide a compressive force to adjacent inner loops of the wire in the coil shape, thereby further causing the wire or the magnets to cut through the layers of tissue and create a shunt of a diameter less than the diameter of the outer loops such that the at least two outer loops do not pass through said shunt.
A sterile formulation for injection comprising a thermosensitive hydrogel, tris (hydroxymethyl) amino methane in an amount sufficient to provide a neutral or slightly basic pH, and an effective amount of collagenase said formulation capable upon injection into a therapeutic target site in a subject having need of collagenase treatment, of providing to said site free, active collagenase and a gel capable of slow release of active collagenase over an extended period, wherein the thermosensitive hydrogel is a triblock polymer of the structure PLGA-PEG-PLGA, wherein PLGA represents poly (DL-lactic acid co-glycolic acid) and PEG represents poly (ethylene glycol).
A network device for estimating a location of a terminal device in a wireless network, wherein the network device is configured to: receive channel state information, CSI, associated with the terminal device ; obtain two or more neural network models ; input the CSI to each of the two or more neural network models ; obtain a set of estimations of the location of the terminal device as outputs of the two or more neural network models ; and determine a final estimation of the location of the terminal device based on the obtained set of estimations, wherein for obtaining the two or more neural network models , the network device is configured to: determine a signal strength based on the CSI ; estimate a coverage area of the CSI based on the signal strength; and determine the two or more neural network models based on the estimated coverage area. receive channel state information, CSI, associated with the terminal device ; obtain two or more neural network models ; input the CSI to each of the two or more neural network models ; obtain a set of estimations of the location of the terminal device as outputs of the two or more neural network models ; and determine a final estimation of the location of the terminal device based on the obtained set of estimations, wherein for obtaining the two or more neural network models , the network device is configured to: determine a signal strength based on the CSI ; estimate a coverage area of the CSI based on the signal strength; and determine the two or more neural network models based on the estimated coverage area. determine a signal strength based on the CSI ; estimate a coverage area of the CSI based on the signal strength; and determine the two or more neural network models based on the estimated coverage area.
Melting fuse with - a melting wire arranged between a first and a second terminal , wherein - a connecting pin is arranged on each of the first and second terminals , and - a printed circuit board is placed on the connection pins characterized in that - at least one integrated circuit is arranged on the printed circuit board on the side facing away from the melting wire , - the integrated circuit comprises at least one microcontroller , and - the integrated circuit is electrically powered via the connection pins , wherein the integrated circuit is operated by the voltage drop across the melting wire . - a melting wire arranged between a first and a second terminal , wherein - a connecting pin is arranged on each of the first and second terminals , and - a printed circuit board is placed on the connection pins - at least one integrated circuit is arranged on the printed circuit board on the side facing away from the melting wire , - the integrated circuit comprises at least one microcontroller , and - the integrated circuit is electrically powered via the connection pins ,
A conductive paste composition comprising: silver-coated copper nanowires with a core-shell structure; a binder mixture containing a silicone resin binder and a hydrocarbon-based resin binder; and an organic solvent, wherein the silver-coated copper nanowires of the core-shell structure are contained in an amount of 5 to 30% by weight based on the weight of the total composition, wherein the weight ratio of the binder mixture including the silicon resin binder and the hydrocarbon-based resin binder, to the silver-coated copper nanowire is 1:0.1 to 1.2. wherein the silver-coated copper nanowires of the core-shell structure are contained in an amount of 5 to 30% by weight based on the weight of the total composition, wherein the weight ratio of the binder mixture including the silicon resin binder and the hydrocarbon-based resin binder, to the silver-coated copper nanowire is 1:0.1 to 1.2.