mhurhangee/patent-ind-claim-en huggingface dataset:
A method for purifying an Fc-containing monoclonal antibody, the method comprising: (a) providing a load fluid comprising said antibody and one or more impurities; (b) contacting the load fluid with a medium, wherein said medium is a Protein A chromatography column, and wherein the antibody binds to the medium under suitable conditions, thereby providing a bound medium; (c) contacting the bound medium with a first wash solution through the bound medium, wherein said first wash solution comprises arginine or an arginine derivative selected from acetyl arginine, agmatine, arginic acid, N-alpha-butyroyl-L-arginine, N-alpha-pyvaloyl arginine, at a concentration of at least 0.5 M but less than 1.0 M, and wherein the pH of the wash solution is between 5.0 and 8.0, thereby providing a washed medium; (d) contacting the washed medium with an elution solution under conditions suitable for eluting the antibody thereby generating an eluate comprising the antibody, and (e) collecting the eluate comprising the antibody. (a) providing a load fluid comprising said antibody and one or more impurities; (b) contacting the load fluid with a medium, wherein said medium is a Protein A chromatography column, and wherein the antibody binds to the medium under suitable conditions, thereby providing a bound medium; (c) contacting the bound medium with a first wash solution through the bound medium, wherein said first wash solution comprises arginine or an arginine derivative selected from acetyl arginine, agmatine, arginic acid, N-alpha-butyroyl-L-arginine, N-alpha-pyvaloyl arginine, at a concentration of at least 0.5 M but less than 1.0 M, and wherein the pH of the wash solution is between 5.0 and 8.0, thereby providing a washed medium; (d) contacting the washed medium with an elution solution under conditions suitable for eluting the antibody thereby generating an eluate comprising the antibody, and (e) collecting the eluate comprising the antibody.
A superconducting wire, comprising: a low-temperature superconducting filament ; a stabilizing matrix encompassing the filament ; and a sheath of a Metal-Insulator Transition (MIT) material, which encompasses the stabilizing matrix on the exterior of the stabilizing matrix, wherein the MIT material has a transition temperature of a room temperature or lower and the transition temperature of the MIT is higher than a critical temperature of the super-conducting material of the filament . a low-temperature superconducting filament ; a stabilizing matrix encompassing the filament ; and a sheath of a Metal-Insulator Transition (MIT) material, which encompasses the stabilizing matrix on the exterior of the stabilizing matrix, wherein the MIT material has a transition temperature of a room temperature or lower and the transition temperature of the MIT is higher than a critical temperature of the super-conducting material of the filament .
A formulation for use in treating Alzheimer's disease wherein the formulation is a cyclopropanated PUFA-cholesterol conjugate and at least one retinoid, wherein the cyclopropanated PUFA-cholesterol conjugate is: wherein the at least one retinoid is selected from retinoic acid, N-(4-hydroxyphenyl) retinamide ("4-HPR"), 4-( 5, 5, 8, 8-Tetramethyl-5, 6, 7, 8-tetrahydronaphthalen-2-ylethynyl) benzoic acid ("ec23"), 9-cis retinoic acid, 13-cis retinoic acid, all-trans-4-hydroxyretinoic acid, all-trans-4-oxoretinoic acid, 3,4, didehydroretinoic acid, retinol, retroretinol, all-trans-4-hydroxyretinol, all-trans-4-oxoretinol, 14-hydroxy-4, 14-retroretinol, retinaldehyde,lycopene, apo-1 0' -lycopenoic acid, and acycloretinoic acid.
A cold generator , comprising a refrigerant circuit with a refrigerant compressor arranged in the refrigerant circuit , a heat-emitting heat exchanger connected to a highpressure connection of the refrigerant compressor , an expansion member following on from the heat-emitting heat exchanger , and a heat-absorbing heat exchanger following on from the expansion member , which heat-absorbing heat exchanger is in turn connected on the output side to an intake connection of the refrigerant compressor , wherein the cold generator comprises a heat exchanger unit in which the heat-emitting heat exchanger and the heat-absorbing heat exchanger are integrated, wherein the heat exchanger unit comprises a flow path layer stack which is built up in a stacked construction and has flow path layers arranged successively in a stack direction , wherein, in order to form the heat-emitting heat exchanger in the flow path layer stack , at least one heat-emitting refrigerant flow path and at least one heat-absorbing second heat transport flow path are provided, wherein a second heat transport medium guided in a second heat transport circuit is arranged to flow through the second heat transport flow path , wherein at least one heat-absorbing refrigerant flow path and at least one heat-emitting first heat transport flow path are provided in order to form the heat-absorbing heat exchanger in the flow path layer stack , and wherein a first heat transport medium guided in a first heat transport circuit is arranged to flow through the first heat transport flow path , characterised in that the heat-emitting refrigerant flow path and the heat-emitting first heat transport flow path are arranged in a flow path layer of the flow path layer stack , and/or the heat-absorbing refrigerant flow path and the heat-absorbing second heat transport flow path are arranged in a flow path layer of the flow path layer stack .
A cutter bar for mounting on a harvester with a frame , the frame having swing arms pointing in the working direction, at the front ends of which cutting elements for cutting the crop are fastened, the swing arms with the cutting elements fastened thereto being movable in height relative to the frame and one or more support elements are mounted on the swing arms , which support conveying surfaces located above the swing arm , characterized in that at least one of the support elements is longitudinally movably connected to the swing arm .
An orthodontic appliance (20, 20 1 , 202) for moving and aligning at least one tooth of a set of teeth of at least one of an upper jaw and a lower jaw of a patient, the orthodontic appliance (20, 20 1 , 20 2 ) comprising: A mouthpiece ; a force exerting member for applying a force to and moving the at least one tooth ; a tooth movement sensor member or arrangement (80, 84, 86 1 , 86 2 , 88) attached to or partially embedded in an interior surface of a facial wall and/or a lingual wall or a base wall of the mouthpiece , or attached to or embedded in the interior surface of the facial wall and/or the lingual wall or the base wall of the mouthpiece , or attached to, partially embedded in, or fully embedded in an exterior surface of the base wall of the mouthpiece , or attached to or embedded in an inner surface of the facial wall and/or the lingual wall and/or the base wall of the mouthpiece , the tooth movement sensor member or arrangement (80, 84, 86 1 , 86 2 , 88) for obtaining at least one of tooth movement data, tooth position data, and tooth identification data; and a tooth movement monitor (82, 82 1 , 82 2 ) for calculating at least one of an amount of tooth movement and a tooth position from the at least one of the tooth movement data, the tooth position data, and the tooth identification data obtained with the tooth movement sensor member (80, 84, 86 1 , 86 2 , 88). A mouthpiece ; a force exerting member for applying a force to and moving the at least one tooth ; a tooth movement sensor member or arrangement (80, 84, 86 1 , 86 2 , 88) attached to or partially embedded in an interior surface of a facial wall and/or a lingual wall or a base wall of the mouthpiece , or attached to or embedded in the interior surface of the facial wall and/or the lingual wall or the base wall of the mouthpiece , or attached to, partially embedded in, or fully embedded in an exterior surface of the base wall of the mouthpiece , or attached to or embedded in an inner surface of the facial wall and/or the lingual wall and/or the base wall of the mouthpiece , the tooth movement sensor member or arrangement (80, 84, 86 1 , 86 2 , 88) for obtaining at least one of tooth movement data, tooth position data, and tooth identification data; and a tooth movement monitor (82, 82 1 , 82 2 ) for calculating at least one of an amount of tooth movement and a tooth position from the at least one of the tooth movement data, the tooth position data, and the tooth identification data obtained with the tooth movement sensor member (80, 84, 86 1 , 86 2 , 88).
A fuel cell system comprising: power modules comprising cabinets, hot boxes located in the cabinets, and fuel cells located in the hot boxes; and an exhaust flue comprising: an outer duct configured to receive relatively cool cabinet exhaust from the cabinets of the power modules; and an inner duct disposed inside of the outer duct and configured to receive relatively hot reaction exhaust from the hot boxes of the power modules. power modules comprising cabinets, hot boxes located in the cabinets, and fuel cells located in the hot boxes; and an exhaust flue comprising: an outer duct configured to receive relatively cool cabinet exhaust from the cabinets of the power modules; and an inner duct disposed inside of the outer duct and configured to receive relatively hot reaction exhaust from the hot boxes of the power modules. an outer duct configured to receive relatively cool cabinet exhaust from the cabinets of the power modules; and an inner duct disposed inside of the outer duct and configured to receive relatively hot reaction exhaust from the hot boxes of the power modules.
Apparatus for the automated separation of small colourless untreated natural diamonds from: a) colourless diamond imitations; b) colourless treated natural diamonds; c) colourless untreated synthetic diamonds and d) colourless treated synthetic diamonds; wherein the small diamonds are round and polished and have a mean diameter smaller than about 3.5 mm; comprising: supporting means for supporting diamonds or diamond imitations, wherein said supporting means is a disk; feeding means for bringing diamonds or diamond imitations on said supporting means ; moving means for moving said supporting means , wherein the moving means is a rotating means for rotating the disk; detection means for submitting colourless diamonds or diamond imitations to a Raman Shift Detection (RSD), first removing means for removing the colourless diamonds or diamond imitations having, at a predetermined wavelength (W e ), an emission signal, the intensity of which is lower than a predetermined value (V e ); measurement means for carrying out a UVc transmission measurement on the remaining colourless diamonds, second removing means for removing the colourless diamonds having, in a predetermined wavelength region (R a ), a transmission value (V T ) higher than a predetermined value (V T' ), and means for recovering the colourless untreated natural diamonds. a) colourless diamond imitations; b) colourless treated natural diamonds; c) colourless untreated synthetic diamonds and d) colourless treated synthetic diamonds; supporting means for supporting diamonds or diamond imitations, wherein said supporting means is a disk; feeding means for bringing diamonds or diamond imitations on said supporting means ; moving means for moving said supporting means , wherein the moving means is a rotating means for rotating the disk; detection means for submitting colourless diamonds or diamond imitations to a Raman Shift Detection (RSD), first removing means for removing the colourless diamonds or diamond imitations having, at a predetermined wavelength (W e ), an emission signal, the intensity of which is lower than a predetermined value (V e ); measurement means for carrying out a UVc transmission measurement on the remaining colourless diamonds, second removing means for removing the colourless diamonds having, in a predetermined wavelength region (R a ), a transmission value (V T ) higher than a predetermined value (V T' ), and means for recovering the colourless untreated natural diamonds.
A medical tube clamp for clamping a flexible medical tube , comprising: a tube receiving area which is adapted to receive the medical tube , a first clamping portion including a first clamping jaw which is movable relative to a second clamping portion including a second clamping jaw , wherein the first clamping jaw and the second clamping jaw are respectively formed as a wall-shaped clamping edge, and a closure system for safely positioning the two clamping portions in more than one snap-fit position relative to each other so that, when the closure system is unlocked, the medical tube can be inserted in and removed from the tube clamp , in an open snap-fit position the inserted medical tube cannot be removed and is not clamped, and in a clamping snap-fit position the medical tube is clamped between the first clamping jaw and the second clamping jaw , characterized in that the first clamping jaw is configured to be elastically movable relative to the first clamping portion via a connecting member and/or the second clamping jaw is configured to be elastically movable relative to the second clamping portion via a connecting member . a tube receiving area which is adapted to receive the medical tube , a first clamping portion including a first clamping jaw which is movable relative to a second clamping portion including a second clamping jaw , wherein the first clamping jaw and the second clamping jaw are respectively formed as a wall-shaped clamping edge, and a closure system for safely positioning the two clamping portions in more than one snap-fit position relative to each other so that, when the closure system is unlocked, the medical tube can be inserted in and removed from the tube clamp , in an open snap-fit position the inserted medical tube cannot be removed and is not clamped, and in a clamping snap-fit position the medical tube is clamped between the first clamping jaw and the second clamping jaw , characterized in that the first clamping jaw is configured to be elastically movable relative to the first clamping portion via a connecting member and/or the second clamping jaw is configured to be elastically movable relative to the second clamping portion via a connecting member .
An automated or semi-automated module-based cartilage cell processing device for preparing a cell seeded carrier from a biological material, comprising at least a cartilage preparation module, a cell isolation module, a cell mixing module and a carrier cell seeding module, wherein the cell mixing module and the carrier cell seeding module are integrated; characterised in that the cell seeding module is arranged to measure a volume of the cell suspension in order not to overflow the carrier using a measuring device.
A method of monitoring a flow meter, the method characterized by the steps of: capturing a substantially continuous flow meter output into a pre-error memory , with the substantially continuous flow meter output overwriting an oldest flow meter output stored in the pre-error memory; detecting a predetermined start triggering condition in the substantially continuous flow meter output; transferring a pre-error memory data into an error log when the predetermined start triggering condition is detected; and capturing the substantially continuous flow meter output in the error log after the predetermined start triggering condition is detected; detecting a predetermined end triggering condition in the substantially continuous flow meter output; and reverting to capturing the substantially continuous flow meter output into the pre-error memory after the predetermined end triggering condition is detected, wherein the error log stores pre-error data and post-error data, with the post-error data comprising all flow meter output generated between the predetermined start triggering condition and the predetermined end triggering condition. capturing a substantially continuous flow meter output into a pre-error memory , with the substantially continuous flow meter output overwriting an oldest flow meter output stored in the pre-error memory; detecting a predetermined start triggering condition in the substantially continuous flow meter output; transferring a pre-error memory data into an error log when the predetermined start triggering condition is detected; and capturing the substantially continuous flow meter output in the error log after the predetermined start triggering condition is detected; detecting a predetermined end triggering condition in the substantially continuous flow meter output; and reverting to capturing the substantially continuous flow meter output into the pre-error memory after the predetermined end triggering condition is detected, wherein the error log stores pre-error data and post-error data, with the post-error data comprising all flow meter output generated between the predetermined start triggering condition and the predetermined end triggering condition.
A laminating system for sandwiching a sheet medium in a two-ply sheet in which two sheets are overlapped and partially joined together and applying heat and pressure to bond the two-ply sheet, the laminating system comprising: a sheet separating device to separate the two sheets of the two-ply sheet and sandwich the sheet medium between the two sheets; a laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705) to heat and press the two-ply sheet sandwiching the sheet medium; and a conveyor to convey the two-ply sheet sandwiching the sheet medium from the sheet separating device to the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705), the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705) being disposed above the sheet separating device , characterized in that the conveyor includes a conveyance path to reverse and convey the two-ply sheet sandwiching the sheet medium to the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705), and a conveyance direction of the two-ply sheet in the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705) is opposite to a conveyance direction of the two-ply sheet in the sheet separating device . a sheet separating device to separate the two sheets of the two-ply sheet and sandwich the sheet medium between the two sheets; a laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705) to heat and press the two-ply sheet sandwiching the sheet medium; and a conveyor to convey the two-ply sheet sandwiching the sheet medium from the sheet separating device to the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705), the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705) being disposed above the sheet separating device , characterized in that the conveyor includes a conveyance path to reverse and convey the two-ply sheet sandwiching the sheet medium to the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705), and a conveyance direction of the two-ply sheet in the laminate-fixing device (205, 205', 205", 205′′′, 305, 605, 705) is opposite to a conveyance direction of the two-ply sheet in the sheet separating device .
A magnetron assembly , comprising: a rigid support structure ; a magnet bar structure movably attached to the rigid support structure; at least one actuation mechanism coupled to the rigid support structure and configured to change a distance of the magnet bar structure from a surface of a rotatable target cylinder; a position indicating mechanism associated with the actuation mechanism and operative to measure a position of the magnet bar structure relative to the surface of the rotatable target cylinder; an electronic controller in operative communication with the actuation mechanism; a communications device configured to receive command signals from outside of the magnetron assembly and transmit information signals to outside of the magnetron assembly; characterised in that the magnetron assembly further comprises: a power source fully self-contained within a volume of the magnetron assembly and coupled to the electronic controller, the power source configured to supply energy to the actuation mechanism. a rigid support structure ; a magnet bar structure movably attached to the rigid support structure; at least one actuation mechanism coupled to the rigid support structure and configured to change a distance of the magnet bar structure from a surface of a rotatable target cylinder; a position indicating mechanism associated with the actuation mechanism and operative to measure a position of the magnet bar structure relative to the surface of the rotatable target cylinder; an electronic controller in operative communication with the actuation mechanism; a communications device configured to receive command signals from outside of the magnetron assembly and transmit information signals to outside of the magnetron assembly; characterised in that the magnetron assembly further comprises: a power source fully self-contained within a volume of the magnetron assembly and coupled to the electronic controller, the power source configured to supply energy to the actuation mechanism.
Recovery system allowing a carrier aircraft to at least recover a carrier-borne aircraft in flight, the recovery system comprising a receiver able to be carried by the carrier aircraft and an attachment able to be carried by the carrier-borne aircraft , said receiver having an internal volume emerging into an external environment (EXT) via a through surface , said receiver comprising a hollow guide section , said guide section being flared, said attachment comprising a flared connection section able to be at least partially contained in said internal volume , said recovery system comprising a fixing device reversibly fixing the attachment to the receiver , characterised in that said attachment is rigidly connected to a mast configured to be attached to the carrier-borne aircraft , said mast comprising a segment arranged outside said receiver when said attachment is stowed in the receiver , said guide section being asymmetrical.
Torch for tungsten inert gas welding, in particular a narrow-gap head for tungsten inert gas narrow-gap welding, in which an electrode unit is held in a housing made of a metal by means of an electrode holder and there is a cooling device for cooling the electrode unit , by which liquid cooling medium can be conducted into the electrode holder and out of the electrode holder again, characterized in that - the cooling device comprises at least one electrically conductive separating wall within a shell of the electrode holder for forming cooling channels , at least the at least one separating wall being electrically connected to the electrode unit , the current transfer taking place either exclusively via the separating wall or via the shell and the separating wall , and - an outer surface of the electrode holder is provided with an insulating layer , at least in the region of the housing surrounding the electrode holder . - the cooling device comprises at least one electrically conductive separating wall within a shell of the electrode holder for forming cooling channels , at least the at least one separating wall being electrically connected to the electrode unit , the current transfer taking place either exclusively via the separating wall or via the shell and the separating wall , and - an outer surface of the electrode holder is provided with an insulating layer , at least in the region of the housing surrounding the electrode holder .