A compound according to the following Formula I, its individual enantiomers, its individual diastereoisomers, its hydrates, its solvates, its crystal forms, its individual tautomers or a pharmaceutically acceptable salt thereof, wherein: A is independently selected from B is independently selected from C is independently selected from -N= , -O- and -S-; F, if present, is independently selected from G, if present, is independently selected from and -N= ; H, if present, is independently selected from and -N= ; I, if present, is independently selected from and -N= ; wherein if F, G, H and I are present, then: D is E is s independently elected from and the ring formed by D, E, F, G, H and I is substituted by p substituents represented by R 2 , otherwise if F, G, H and I are absent, then: D is independently selected from -N= and and E is independently selected from and -N= , each X is independently selected form C(R a )R b , wherein one of the C(R a )R b groups can be replaced by a NR a group ; n is 1 or 2; m is 0, 1, 2 or 3; p is 0, 1, 2, or 3; L 1 is phenyl; L 2 is phenyl; R 1 is independently selected from Cl, F, OH, OCH 3 and COOH, and/or two R 1 groups together form part of a 1,3-benzodioxol ring or a 2,3-dihydro-1,4-benzodioxin ring; R 2 is COOH; each R 3 is independently selected from hydrogen, methyl, ethyl, propargyl, -CH 2 COOH, benzyl, unsubstituted phenyl, and substituted phenyl selected from 3-carboxyphenyl and 4-carboxyphenyl; and R a and R b are hydrogen; with the provisos that when the ring fragment is represented by then: R 3 is selected from hydrogen, methyl, benzyl, and substituted phenyl selected from 3-carboxyphenyl and 4-carboxyphenyl; when the ring fragment is represented by then at least one of m and p is larger than 0; and when the ring fragment is represented by then m is larger than 0. A is independently selected from B is independently selected from C is independently selected from -N= , -O- and -S-; F, if present, is independently selected from G, if present, is independently selected from and -N= ; H, if present, is independently selected from and -N= ; I, if present, is independently selected from and -N= ; wherein if F, G, H and I are present, then: D is E is s independently elected from and the ring formed by D, E, F, G, H and I is substituted by p substituents represented by R 2 , D is E is s independently elected from and the ring formed by D, E, F, G, H and I is substituted by p substituents represented by R 2 , otherwise if F, G, H and I are absent, then: D is independently selected from -N= and and E is independently selected from and -N= , D is independently selected from -N= and and E is independently selected from and -N= , each X is independently selected form C(R a )R b , wherein one of the C(R a )R b groups can be replaced by a NR a group ; n is 1 or 2; m is 0, 1, 2 or 3; p is 0, 1, 2, or 3; L 1 is phenyl; L 2 is phenyl; R 1 is independently selected from Cl, F, OH, OCH 3 and COOH, and/or two R 1 groups together form part of a 1,3-benzodioxol ring or a 2,3-dihydro-1,4-benzodioxin ring; R 2 is COOH; each R 3 is independently selected from hydrogen, methyl, ethyl, propargyl, -CH 2 COOH, benzyl, unsubstituted phenyl, and substituted phenyl selected from 3-carboxyphenyl and 4-carboxyphenyl; and R a and R b are hydrogen; with the provisos that when the ring fragment is represented by then: R 3 is selected from hydrogen, methyl, benzyl, and substituted phenyl selected from 3-carboxyphenyl and 4-carboxyphenyl; when the ring fragment is represented by then at least one of m and p is larger than 0; and when the ring fragment is represented by then m is larger than 0. <EOS>