mhurhangee/patent-ind-claim-en huggingface dataset:
An implantable medical device, IMD, configured for use as part of a cardiac therapy system comprising a leadless cardiac pacemaker, LCP , for delivering pacing therapy and the IMD, the IMD comprising: a plurality of electrodes for sensing cardiac activity; communication circuitry configured to communicate with a LCP ; and operational circuitry configured to receive sensed cardiac signals from the plurality of electrodes and analyze cardiac activity, characterized in that the operational circuitry comprises: pace timing means configured to determine when pace therapy is delivered by a LCP; P-wave to Pace means configured to determine a P-wave to Pace interval by analysis of a segment of the sensed cardiac signals from the plurality of electrodes including a time period prior to pace therapy delivery from a LCP ; comparing means configured to determine whether the P-wave to Pace interval is in a desired range or requires adjustment; and adjustment means configured to adjust a parameter of the pacing therapy delivered by a LCP based on the determination of the comparing means . a plurality of electrodes for sensing cardiac activity; communication circuitry configured to communicate with a LCP ; and operational circuitry configured to receive sensed cardiac signals from the plurality of electrodes and analyze cardiac activity, characterized in that the operational circuitry comprises: pace timing means configured to determine when pace therapy is delivered by a LCP; P-wave to Pace means configured to determine a P-wave to Pace interval by analysis of a segment of the sensed cardiac signals from the plurality of electrodes including a time period prior to pace therapy delivery from a LCP ; comparing means configured to determine whether the P-wave to Pace interval is in a desired range or requires adjustment; and adjustment means configured to adjust a parameter of the pacing therapy delivered by a LCP based on the determination of the comparing means . pace timing means configured to determine when pace therapy is delivered by a LCP; P-wave to Pace means configured to determine a P-wave to Pace interval by analysis of a segment of the sensed cardiac signals from the plurality of electrodes including a time period prior to pace therapy delivery from a LCP ; comparing means configured to determine whether the P-wave to Pace interval is in a desired range or requires adjustment; and adjustment means configured to adjust a parameter of the pacing therapy delivered by a LCP based on the determination of the comparing means .
A pharmaceutical composition comprising a bispecific antibody comprising a first antigen-binding site that binds domain I of ErbB-2 and a second antigen-binding site that binds domain III of ErbB-3, wherein the antibody can reduce a ligand-induced receptor function of ErbB-3 on a ErbB-2 and ErbB-3 positive cell, wherein the pharmaceutical composition comprises 5-50 mM Histidine, 100-300 mM Trehalose, 0.1-0.3 g/L PolySorbate20 or a combination thereof.
A machine-readable medium including instructions for providing therapy to a patient, which when executed by a machine operably connected to a plurality of electrodes implanted within the patient, cause the machine to: receive, via a programmer for an electrical stimulator, user input that at least partially defines a neuromodulation field to provide the therapy; based on the received user input, determine a subset of the plurality of electrodes and current distributions for the subset to generate the field; compare an electrode limit to a number of electrodes in the determined subset and eliminate at least one of the number of electrodes in the determined subset based on the comparison to provide a reduced subset of the electrodes; and redistribute current associated with the at least one eliminated electrode to at least one of the electrodes in the reduced subset of electrodes. receive, via a programmer for an electrical stimulator, user input that at least partially defines a neuromodulation field to provide the therapy; based on the received user input, determine a subset of the plurality of electrodes and current distributions for the subset to generate the field; compare an electrode limit to a number of electrodes in the determined subset and eliminate at least one of the number of electrodes in the determined subset based on the comparison to provide a reduced subset of the electrodes; and redistribute current associated with the at least one eliminated electrode to at least one of the electrodes in the reduced subset of electrodes.
A pneumatically, high pressure gas powered emergency release coupling control and monitoring system (S) comprising a powered emergency released coupling (PERC) arranged when in use in a fluid-supply line for conveying hazardous fluids, said powered emergency released coupling comprising a couple of coupling members provided with mating faces for sealing engagement of the coupling members and formation of a pressurizable chamber between said coupling members , said system (S) comprising an actuation line connected at its one end to the pressurizable chamber and at its other end to a source (C) of high pressure gaseous media (G H ), preferably high pressure nitrogen gas, a first actuating device arranged in the actuation line , characterized in that said system (S) provides a gaseous media at a pilot pressure level to said pressurizable chamber and to said actuation line in a position downstream the first actuation device or via said pressurizable chamber for detection of any leakage of gas in the control and monitoring system (S), said pilot pressure gaseous media preferably being low pressure nitrogen gas. said system (S) comprising an actuation line connected at its one end to the pressurizable chamber and at its other end to a source (C) of high pressure gaseous media (G H ), preferably high pressure nitrogen gas, a first actuating device arranged in the actuation line , characterized in that said system (S) provides a gaseous media at a pilot pressure level to said pressurizable chamber and to said actuation line in a position downstream the first actuation device or via said pressurizable chamber for detection of any leakage of gas in the control and monitoring system (S), said pilot pressure gaseous media preferably being low pressure nitrogen gas.
A radiation detector comprising: a) a directly converting semiconductor layer for converting an incident radiation into electrical signals; b) a substrate comprising readout electronics for receiving said electrical signals via pixel pads arranged at said directly converting semiconductor layer ; and c) a plurality of infrared radiation sources (30; 32) connected or integrated to said substrate and adapted to irradiate said directly converting semiconductor layer ; characterized in that d) said plurality of infrared radiation sources (30; 32) are provided on an infrared source layer which is interposed between said directly converting semiconductor layer and a readout chip of said substrate and which is flip-chip bonded to said directly converting semiconductor layer via said pixel pads , wherein said infrared source layer comprises through connection portions for electrically connecting said pixel pads to related contact portions on said readout chip . a) a directly converting semiconductor layer for converting an incident radiation into electrical signals; b) a substrate comprising readout electronics for receiving said electrical signals via pixel pads arranged at said directly converting semiconductor layer ; and c) a plurality of infrared radiation sources (30; 32) connected or integrated to said substrate and adapted to irradiate said directly converting semiconductor layer ; characterized in that d) said plurality of infrared radiation sources (30; 32) are provided on an infrared source layer which is interposed between said directly converting semiconductor layer and a readout chip of said substrate and which is flip-chip bonded to said directly converting semiconductor layer via said pixel pads , wherein said infrared source layer comprises through connection portions for electrically connecting said pixel pads to related contact portions on said readout chip .
A pre-vapor formulation of an e-vaping device, the pre-vapor formulation comprising: an ion exchanger or an ion exchanger and a chelating agent; nicotine; and a vapor former configured to form a vapor of the pre-vapor formulation, wherein the ion exchanger comprises at least one of styrene-divinylbenzene, a crosslinked polyacrylate carboxylic acid and a styrene divinylbenzene copolymer. an ion exchanger or an ion exchanger and a chelating agent; nicotine; and a vapor former configured to form a vapor of the pre-vapor formulation, wherein the ion exchanger comprises at least one of styrene-divinylbenzene, a crosslinked polyacrylate carboxylic acid and a styrene divinylbenzene copolymer.
An apparatus comprising: a temperature control system (TCS, 205) configured to regulate temperatures of multiple stages of a multi-stage cryocooler , the temperature control system comprising: an input interface configured to receive (i) temperature setpoints for at least two of the stages of the multi-stage cryocooler and (ii) temperature information corresponding to temperatures measured at the at least two of the stages of the multi-stage cryocooler; processing circuitry configured to determine temperature errors for the at least two of the stages using the temperature setpoints and the temperature information, and to calculate for each of the at least two of the stages at least one of a compressor stroke error and a pressure-volume phase error, using the temperature errors; and at least one controller configured to adjust at least one of a compressor setting and a pressure-volume phase of the multi-stage cryocooler for each of the at least two of the stages, to regulate the temperatures of the at least two of the stages independently, using at least one of the compressor stroke error and the pressure-volume phase error. an input interface configured to receive (i) temperature setpoints for at least two of the stages of the multi-stage cryocooler and (ii) temperature information corresponding to temperatures measured at the at least two of the stages of the multi-stage cryocooler; processing circuitry configured to determine temperature errors for the at least two of the stages using the temperature setpoints and the temperature information, and to calculate for each of the at least two of the stages at least one of a compressor stroke error and a pressure-volume phase error, using the temperature errors; and at least one controller configured to adjust at least one of a compressor setting and a pressure-volume phase of the multi-stage cryocooler for each of the at least two of the stages, to regulate the temperatures of the at least two of the stages independently, using at least one of the compressor stroke error and the pressure-volume phase error.
A modular motor control system comprising: a master controller ; a first motor configured to control a first movement of a surgical instrument; and a first motor controller operatively coupled to the first motor, wherein the first motor controller and the master controller are in electrical communication, wherein the master controller provides a first control signal to the first motor controller, wherein the first motor controller controls the first motor in response to the first control signal, a second motor configured to control a second movement of the surgical instrument; a second motor controller operatively coupled to the second motor, wherein the second motor controller and the master controller are in electrical communication, wherein the master controller provides a second control signal to the second motor controller, wherein the second motor controller controls the second motor in response to the second control signal; wherein the first motor controller comprises a closed-loop control process having one or more independent controls for the first motor, and wherein the second motor controller comprises a closed-loop control process having one or more independent controls for the second motor, characterised in that the one or more independent controls of the first motor controller comprise a force limiting control process, and wherein the one or more independent controls of the second motor controller comprise a force limiting control process. a master controller ; a first motor configured to control a first movement of a surgical instrument; and a first motor controller operatively coupled to the first motor, wherein the first motor controller and the master controller are in electrical communication, wherein the master controller provides a first control signal to the first motor controller, wherein the first motor controller controls the first motor in response to the first control signal, a second motor configured to control a second movement of the surgical instrument; a second motor controller operatively coupled to the second motor, wherein the second motor controller and the master controller are in electrical communication, wherein the master controller provides a second control signal to the second motor controller, wherein the second motor controller controls the second motor in response to the second control signal; wherein the first motor controller comprises a closed-loop control process having one or more independent controls for the first motor, and wherein the second motor controller comprises a closed-loop control process having one or more independent controls for the second motor, characterised in that the one or more independent controls of the first motor controller comprise a force limiting control process, and wherein the one or more independent controls of the second motor controller comprise a force limiting control process.
Device for accommodating plant material from a group comprising seed, a cutting, a seedling or other plant material, the device comprising: more than one tubular holders (27-30) to contain the plant material and possibly a substrate material , wherein the bottoms of the holders are open, - a closing element to close the bottoms of the holders (27-30) and which can be removed to flush or blow the plant material from the bottoms of the holders, and - a coupling to mutually couple the holders, wherein the coupling comprises a foldable member for the purpose of setting out the holders to be exposed to light at predetermined mutual intermediate distances in an extended position of the foldable member or for allowing the holders to be transported in space-saving manner in a compressed position of the foldable member. - a closing element to close the bottoms of the holders (27-30) and which can be removed to flush or blow the plant material from the bottoms of the holders, and - a coupling to mutually couple the holders, wherein the coupling comprises a foldable member for the purpose of setting out the holders to be exposed to light at predetermined mutual intermediate distances in an extended position of the foldable member or for allowing the holders to be transported in space-saving manner in a compressed position of the foldable member.
An implant system comprising: a tool having a shaft , a first projection and a second projection ; a baseplate having a post and a first fastener aperture ; and an augment having a first opening configured to lockingly receive the post, wherein the first projection of the tool is rotatable about a longitudinal axis of the shaft of the tool and is insertable into the first fastener aperture of the baseplate and the second projection is fixed about a longitudinal axis of the shaft of the tool and whereinwhen the first projection of the tool is inserted into the first fastener aperture, the first projection acts as a guide that directs the post of the baseplate into the first opening of the augment along a pre-defined trajectory. a tool having a shaft , a first projection and a second projection ; a baseplate having a post and a first fastener aperture ; and an augment having a first opening configured to lockingly receive the post, wherein the first projection of the tool is rotatable about a longitudinal axis of the shaft of the tool and is insertable into the first fastener aperture of the baseplate and the second projection is fixed about a longitudinal axis of the shaft of the tool and whereinwhen the first projection of the tool is inserted into the first fastener aperture, the first projection acts as a guide that directs the post of the baseplate into the first opening of the augment along a pre-defined trajectory.
Axle drive apparatus for a motor vehicle, having at least one drive unit , which is operatively connected to an input shaft of a gearbox connecting the drive unit to a wheel axle , wherein the gearbox is designed as a multi-speed linear cam gearbox, which has a linear cam , which sets different ratios between the input shaft and an output shaft of the gearbox in different positions, wherein the linear cam is connected to a centrifugal governor , characterised in that the centrifugal governor displaces the linear cam as a function of a rotational speed of the input shaft , wherein the centrifugal governor has at least one centrifugal force element , which can be displaced in a radial direction, mounted on the input shaft , which is operatively connected to the linear cam via a lever assembly .
A process for converting alkylmethoxyphenols, wherein alkylmethoxyphenols are demethoxylated in the presence of an aromatic solvent and a first catalyst to form alkylphenols, wherein the first catalyst contains a metal selected from groups consisting of Group 5 (VB), Group 6 (VIB), Group 7 (VI IB), Group 8 (VIIIB), Group 9 (VIIIB), Group 10 (VIIIB), Group 11 (IB), Group 12 (IIB), Group 13 (IIIA), Group 14 (IVA), Group 15 (VA) and Group 16 (VIA), wherein the IUPAC group number appears first and an old system of group numbers appears in parenthesis, or any alloy or mixture thereof, combined with a support selected from the group consisting of activated carbon, mesoporous carbon, aluminum oxide, zeolites, titanium oxide, cerium oxide, molybdenum oxide, zinc oxide, iron oxide, vanadium, zirconium oxide and silicon oxide, wherein the aromatic solvents are selected from the group consisting of benzene, toluene, ethylbenzene, propylbenzene or combinations thereof.
Use of an adhesive tape to sheath elongate material, wherein a) the adhesive tape is led helically around the elongate material or b) the elongate material is axially enveloped by the tape, wherein the adhesive tape comprises a biobased carrier material, wherein the biobased carrier material is in the form of sheetlike elements comprising spun, woven and/or molten sheetlike elements, comprising a biobased polyester wherein - either or both of the surfaces of the biobased carrier material is provided with - at least one adhesive material, which may be wholly or partly sunk into the carrier, and - optionally at least one facing material and/or transfer material, characterized in that the biobased polyester is based on at least two different biobased monomers derived from biomass-containing carbohydrates where at least one biobased monomer is a furan derivative of formula I where - R1 is independently a carboxyl group and by way of substituent contains a linear, branched and/or cyclic substituted or unsubstituted hydrocarbyl group having 1 to 20 carbon atoms which optionally contains O, N or S atoms, or is a carboxylic acid group or an anhydride, and - R2 is independently a carboxyl group and by way of substituent comprises a linear, branched and/or cyclic substituted or unsubstituted hydrocarbyl group having 1 to 20 carbon atoms, or is a carboxylic acid group or an anhydride, the second biobased monomer is a hydroxyl-functional compound comprising 1 to 100 carbon atoms, wherein the polyester has an average molecular weight Mw of greater than or equal to 1000 g/mol (measured by the measuring method specified in the description) and the proportion of biobased monomers in the biobased polyester is greater than or equal to 55 mol% relative to all monomers of the polyester, wherein the proportion of biobased monomers in the biobased polyester is determined via the ratio of 14 C/ 12 C carbon atoms. a) the adhesive tape is led helically around the elongate material or b) the elongate material is axially enveloped by the tape, - either or both of the surfaces of the biobased carrier material is provided with - at least one adhesive material, which may be wholly or partly sunk into the carrier, and - optionally at least one facing material and/or transfer material, - R1 is independently a carboxyl group and by way of substituent contains a linear, branched and/or cyclic substituted or unsubstituted hydrocarbyl group having 1 to 20 carbon atoms which optionally contains O, N or S atoms, or is a carboxylic acid group or an anhydride, and - R2 is independently a carboxyl group and by way of substituent comprises a linear, branched and/or cyclic substituted or unsubstituted hydrocarbyl group having 1 to 20 carbon atoms, or is a carboxylic acid group or an anhydride,
A temporary storage system storing articles temporarily between overhead transfer vehicles and at least a load port of processing equipment comprising: a travelling rail provided over the processing equipment except for an area over the load port and comprising longitudinal rails and lateral rails arranged with a gap so that openings through which articles may pass are formed by the gap; buffers provided under the openings of the travelling rail ; and local vehicles comprising a carriage configured to travel over and along said travelling rail and a transfer unit supported by the carriage , wherein the carriage is provided with at least a longitudinal travelling unit configured to travel longitudinally; at least a lateral travelling unit configured to travel laterally; and at least an advancement and retraction mechanism configured to selectively advance one of the longitudinal travelling unit and the lateral travelling unit to a position supported by said travelling rail , and configured to be capable of travelling along said travelling rail longitudinally and laterally, wherein said transfer unit is provided with a hoist to raise and lower an article and a hoist transport unit configured to move the hoist laterally, and wherein said local vehicles are configured to stop at a position corresponding to the load port and to advance the hoist transport unit towards the load port so as to transfer an article to and from the load port . a travelling rail provided over the processing equipment except for an area over the load port and comprising longitudinal rails and lateral rails arranged with a gap so that openings through which articles may pass are formed by the gap; buffers provided under the openings of the travelling rail ; and local vehicles comprising a carriage configured to travel over and along said travelling rail and a transfer unit supported by the carriage , wherein the carriage is provided with at least a longitudinal travelling unit configured to travel longitudinally; at least a lateral travelling unit configured to travel laterally; and at least an advancement and retraction mechanism configured to selectively advance one of the longitudinal travelling unit and the lateral travelling unit to a position supported by said travelling rail , and configured to be capable of travelling along said travelling rail longitudinally and laterally, wherein said transfer unit is provided with a hoist to raise and lower an article and a hoist transport unit configured to move the hoist laterally, and wherein said local vehicles are configured to stop at a position corresponding to the load port and to advance the hoist transport unit towards the load port so as to transfer an article to and from the load port .