mhurhangee/patent-ind-claim-en huggingface dataset:
An in vitro method for identifying an anti-cancer agent, the therapeutic efficacy of which is enhanced upon administration with a second agent that increases the expression of opioid receptor kappa-1 (OPRK1), comprising the steps of: a. co-incubating a population of cells with a target anti-cancer agent and said second agent and b. measuring the cytotoxicity and/or cytostasis in the population of cells; wherein the therapeutic efficacy of the target anti-cancer agent is identified as enhanced if the cytotoxicity and/or cytostasis of the target anti-cancer agent is increased compared to a control, wherein the second agent is 6-β-naltrexol, naltrexone, methlynaltrexone or a pharmaceutically acceptable salt thereof and wherein the second agent is incubated with the population of cells prior to the addition of the target anti-cancer agent for a sufficient time to enable the level of expression of OPRK1 to increase by at least 25% compared to the normal basal levels expected in the specific cancer cell type. a. co-incubating a population of cells with a target anti-cancer agent and said second agent and b. measuring the cytotoxicity and/or cytostasis in the population of cells; wherein the therapeutic efficacy of the target anti-cancer agent is identified as enhanced if the cytotoxicity and/or cytostasis of the target anti-cancer agent is increased compared to a control, wherein the second agent is 6-β-naltrexol, naltrexone, methlynaltrexone or a pharmaceutically acceptable salt thereof and wherein the second agent is incubated with the population of cells prior to the addition of the target anti-cancer agent for a sufficient time to enable the level of expression of OPRK1 to increase by at least 25% compared to the normal basal levels expected in the specific cancer cell type. wherein the therapeutic efficacy of the target anti-cancer agent is identified as enhanced if the cytotoxicity and/or cytostasis of the target anti-cancer agent is increased compared to a control, wherein the second agent is 6-β-naltrexol, naltrexone, methlynaltrexone or a pharmaceutically acceptable salt thereof and wherein the second agent is incubated with the population of cells prior to the addition of the target anti-cancer agent for a sufficient time to enable the level of expression of OPRK1 to increase by at least 25% compared to the normal basal levels expected in the specific cancer cell type.
A metal mask material, the metal mask material is characterised by including, by mass%, C: 0.01% or less, Si: 0.5% or less, Mn: 1.0% or less, and Ni: 30 to 50%, with the balance being made up of Fe and inevitable impurities, wherein for the metal mask material, both a surface roughness in a rolling direction and a surface roughness in a direction perpendicular to the rolling direction have an arithmetic average roughness Ra of 0.05 μm or more and 0.25 μm or less and a maximum height Rz of 1.5 μm or less, and a skewness Rsk is less than 0, and wherein, when a sample with a length of 150 mm and a width of 30 mm is cut out from the metal mask material and 60% of the plate thickness of the sample is removed by etching the sample from one side, an amount of warpage is 15 mm or less, and the plate thickness is 0.01 mm or more and less than 0.10 mm.
An asphalt-based sealcoat composition comprising an asphalt emulsion, water, an extender, sand, a polymer emulsion, clay, fiber, and titanium oxide (TiOz) particles, wherein the asphalt emulsion is present in an amount of 5% to 40% by weight; the water is present in an amount of 15% to 45% by weight; the extender is present in an amount of 1% to 10% by weight; the sand is present in an amount of 5% to 20% by weight; polymer emulsion is present in an amount of 1% to 35% by weight; the clay is present in an amount of 1% to 10% by weight; the fiber is present in an amount of 0.1% to 5% by weight; and the TiO 2 particles are present in an amount of 20.5% to 60% by weight. the asphalt emulsion is present in an amount of 5% to 40% by weight; the water is present in an amount of 15% to 45% by weight; the extender is present in an amount of 1% to 10% by weight; the sand is present in an amount of 5% to 20% by weight; polymer emulsion is present in an amount of 1% to 35% by weight; the clay is present in an amount of 1% to 10% by weight; the fiber is present in an amount of 0.1% to 5% by weight; and the TiO 2 particles are present in an amount of 20.5% to 60% by weight.
A medical device accessory , comprising: an interface configured to connect the medical device accessory with a medical device for administration of a medical treatment using the medical device and the medical device accessory; a plurality of electrical contacts (116, 118, 120, 122 and 124) proximate the interface, the electrical contacts comprising a lead electrical contact adapted to receive a voltage from a power source associated with the medical device and one or more identifying electrical contacts; and at least one conductor providing an electrical connection between the lead electrical contact and the one or more identifying electrical contacts; wherein a spatial arrangement of the one or more identifying electrical contacts connected to the lead electrical contact identifies a characteristic of the medical device accessory, wherein a conductor of the at least one conductor is configured for alignment with a severing element associated with the medical device and characterized in that said conductor is mechanically severable upon disconnection of the medical device accessory with the medical device. an interface configured to connect the medical device accessory with a medical device for administration of a medical treatment using the medical device and the medical device accessory; a plurality of electrical contacts (116, 118, 120, 122 and 124) proximate the interface, the electrical contacts comprising a lead electrical contact adapted to receive a voltage from a power source associated with the medical device and one or more identifying electrical contacts; and at least one conductor providing an electrical connection between the lead electrical contact and the one or more identifying electrical contacts; wherein a spatial arrangement of the one or more identifying electrical contacts connected to the lead electrical contact identifies a characteristic of the medical device accessory, wherein a conductor of the at least one conductor is configured for alignment with a severing element associated with the medical device and characterized in that said conductor is mechanically severable upon disconnection of the medical device accessory with the medical device.
A battery module , comprising: a battery cell arrangement structure comprising a plurality of battery cells stacked upon one another in a length direction (X); a cable tie , the cable tie surrounding outside the battery cell arrangement structure along the length direction (X), and at least comprising a first cable tie and a second cable tie of different materials, tensile strength of the first cable tie is greater than that of the second cable tie , and an elastic modulus of the first cable tie is greater than that of the second cable tie ; and an end plate , and the end plate is located on an end of the battery cell arrangement structure in the length direction (X), the end plate and the cable tie form a frame structure, and the frame structure is used for accommodating the battery cell arrangement structure , the end plate is provided with a first mounting groove , and a part of the first cable tie and a part of the second cable tie are located in the first mounting groove ; and wherein the first cable tie and the second cable tie have overlapping parts in a height direction (Z), and at least part of the first cable tie is abutted with the second cable tie in the height direction (Z), at least part of the first cable tie is located on inside of the second cable tie , the inside is a side of the second cable tie close to the battery cell arrangement structure . a battery cell arrangement structure comprising a plurality of battery cells stacked upon one another in a length direction (X); a cable tie , the cable tie surrounding outside the battery cell arrangement structure along the length direction (X), and at least comprising a first cable tie and a second cable tie of different materials, tensile strength of the first cable tie is greater than that of the second cable tie , and an elastic modulus of the first cable tie is greater than that of the second cable tie ; and an end plate , and the end plate is located on an end of the battery cell arrangement structure in the length direction (X), the end plate and the cable tie form a frame structure, and the frame structure is used for accommodating the battery cell arrangement structure , the end plate is provided with a first mounting groove , and a part of the first cable tie and a part of the second cable tie are located in the first mounting groove ; and wherein the first cable tie and the second cable tie have overlapping parts in a height direction (Z), and at least part of the first cable tie is abutted with the second cable tie in the height direction (Z), at least part of the first cable tie is located on inside of the second cable tie , the inside is a side of the second cable tie close to the battery cell arrangement structure .
The triazole or triazolothiadiazine derivative, characterized in that it is selected from the following group: 6-Phenyl-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(4-Nitrophenyl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(4-Fluorophenyl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(4-Chlorophenyl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(4-Bromophenyl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(4-Cyanophenyl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 3-(2-(Pyridine-3-yl)ethyl)-6-(4-(trifluoromethyl)phenyl)-7 H- triazolo[3,4- b ] thiadiazine 3-(2-(Pyridine-3-yl)ethyl)-6-( p -tolyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(4-Methoxyphenyl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 6-(Naphthalene-2-yl)-3-(2-(pyridine-3-yl)ethyl)-7 H - triazolo[3,4- b ] thiadiazine 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N- (thiazole-2-yl)acetamide 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N- (benzothiazole-2-yl)acetamide 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N -(6-fluorobenzothiazole-2-yl)acetamide 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N -(6-chlorobenzothiazole-2-yl)acetamide 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N -(6-bromobenzothiazole-2-yl)acetamide 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N -(6-methylbenzothiazole-2-yl)acetamide 2-((4-Amino-5-(2-(pyridine-3-yl)ethyl)-4 H -1,2,4-triazole-3-yl)thio)- N -(6-methoxybenzothiazole-2-yl)acetamide
A method to produce a secure hash value (R) from a plaintext (P), characterised in that said method comprising : - producing a first result (H) using an hash function of the plaintext (P), - obtaining an initial floating value (U0) by converting the first result (H) into a floating number representation of the first value (H), - updating a floating value (Un) by executing at least once a Transcendental function (TF) on the initial floating value (Un-1), - obtaining the secure hash value (R) by mixing the first result (H) with the updated floating value (Un), wherein the mixing comprises any mathematical operation such as addition, subtraction, multiplication or division, or a Boolean operation such a XOR, XNOR. - producing a first result (H) using an hash function of the plaintext (P), - obtaining an initial floating value (U0) by converting the first result (H) into a floating number representation of the first value (H), - updating a floating value (Un) by executing at least once a Transcendental function (TF) on the initial floating value (Un-1), - obtaining the secure hash value (R) by mixing the first result (H) with the updated floating value (Un), wherein the mixing comprises any mathematical operation such as addition, subtraction, multiplication or division, or a Boolean operation such a XOR, XNOR.
A method, comprising: presenting a credential to a non-networked local host , said local host comprising a reader configured to communicate with the credential and being associated with an access control system for controlling access to an asset; performing authentication between said local host and said credential , using a control key (KD1) shared between said credential and said local host, prior to said local host transmitting data; said local host transmitting data comprising a host identifier and a timestamp to said credential ; said credential analyzing the host identifier and the timestamp using an application stored on said credential , wherein the application compares the received host identifier and the timestamp to data stored in the credential to determine whether access to the asset for that host identifier and at that time of the timestamp is authorized; said credential making an access control decision for itself related to said access control system based on said analyzing step; said credential generating a message containing results of said access control decision; and said credential sending said message to said local host . presenting a credential to a non-networked local host , said local host comprising a reader configured to communicate with the credential and being associated with an access control system for controlling access to an asset; performing authentication between said local host and said credential , using a control key (KD1) shared between said credential and said local host, prior to said local host transmitting data; said local host transmitting data comprising a host identifier and a timestamp to said credential ; said credential analyzing the host identifier and the timestamp using an application stored on said credential , wherein the application compares the received host identifier and the timestamp to data stored in the credential to determine whether access to the asset for that host identifier and at that time of the timestamp is authorized; said credential making an access control decision for itself related to said access control system based on said analyzing step; said credential generating a message containing results of said access control decision; and said credential sending said message to said local host .
Profiled section system comprising at least two profiled elements with a guide device and at least one connecting device for connecting two profiled elements, whereby - the profiled elements have retaining grooves which run in the longitudinal direction and which receive the connecting device in a longitudinally movable manner and are open at the end face in order to insert the connecting device, and - the connecting device has a longitudinal piece with two longitudinal edges , running substantially parallel, which are insertable in a slidable way into opposite, parallel running, retaining grooves of a profile element and which has a rotatable fixing element at opposite ends of the longitudinal piece in each case for fixing to a profiled element (100; 100'), and whereby the fixing elements are provided at opposite ends of the longitudinal piece in such a way that they are to be rotated in opposite directions from an insertion position into a fixing position , characterized in that - the fixing elements are rotatably borne on the longitudinal piece relative to the longitudinal piece, whereby the fixing element comprises an engagement piece which lies in a plane with the longitudinal edges of the longitudinal piece of the connecting device and which is rotated in an insertion position out of engagement with the profile element and in a fixing position in engagement with the profile element in this plane. - the profiled elements have retaining grooves which run in the longitudinal direction and which receive the connecting device in a longitudinally movable manner and are open at the end face in order to insert the connecting device, and - the connecting device has a longitudinal piece with two longitudinal edges , running substantially parallel, which are insertable in a slidable way into opposite, parallel running, retaining grooves of a profile element and which has a rotatable fixing element at opposite ends of the longitudinal piece in each case for fixing to a profiled element (100; 100'), and whereby the fixing elements are provided at opposite ends of the longitudinal piece in such a way that they are to be rotated in opposite directions from an insertion position into a fixing position , - the fixing elements are rotatably borne on the longitudinal piece relative to the longitudinal piece, whereby the fixing element comprises an engagement piece which lies in a plane with the longitudinal edges of the longitudinal piece of the connecting device and which is rotated in an insertion position out of engagement with the profile element and in a fixing position in engagement with the profile element in this plane.
A method of outputting review content (105a-c; 1310-1330; 1410-1430; 1510-1530; 1610-1630) by a device to a user, the method comprising: obtaining attribute information (D,I) of review content that is retrieved by the device; obtaining information regarding the user's memory (e), indicating a level of the user's ability of memorizing content from any one of the following sources: external data that stores bio information such as user's brain waves, an application from which the information in inferred, information of a number of times that the user has repeatedly referred to the content; characterized by obtaining reference information including a reference number of times (c) and a reference time (to) when the review content is selected, wherein the reference number of times (c) refers to the number of times that the review content has been referred to by the user and wherein the reference time (to) refers to when a user input for the review content is detected; estimating a parameter (R) indicative of a probability that the user memorizes the review content at a preset time based on the attribute information (D,I), the reference information (c, to) and the information regarding the user's memory (e); comparing the estimated parameter (R) and a threshold value; and changing an appearance of the review content in response to the comparison of the estimated parameter (R) being determined as equal to or less than the threshold value. obtaining attribute information (D,I) of review content that is retrieved by the device; obtaining information regarding the user's memory (e), indicating a level of the user's ability of memorizing content from any one of the following sources: external data that stores bio information such as user's brain waves, an application from which the information in inferred, information of a number of times that the user has repeatedly referred to the content; characterized by obtaining reference information including a reference number of times (c) and a reference time (to) when the review content is selected, wherein the reference number of times (c) refers to the number of times that the review content has been referred to by the user and wherein the reference time (to) refers to when a user input for the review content is detected; estimating a parameter (R) indicative of a probability that the user memorizes the review content at a preset time based on the attribute information (D,I), the reference information (c, to) and the information regarding the user's memory (e); comparing the estimated parameter (R) and a threshold value; and changing an appearance of the review content in response to the comparison of the estimated parameter (R) being determined as equal to or less than the threshold value.
An addition curable organopolysiloxane release coating composition, comprising: A) at least one organopolysiloxane bearing on average, at least two terminal aliphatically unsaturated groups; B) at least one organopolysiloxane crosslinker bearing silicon-bonded hydrogen ("Si-H") groups, wherein no more than 67 mol percent of siloxy groups in the organopolysiloxane crosslinker contain Si-H groups, wherein at least one organopolysiloxane crosslinker (B) has the formula: where R is a C 1-20 hydrocarbon group containing no aliphatic unsaturation, c is 0, d is 3, p is from 10 to 200, and q is from 5 to 60, where the p diorganosiloxy group, and q hydrogen organosiloxy groups are distributed in any manner; C) at least one hydrosilylation catalyst; and D) optionally, a hydrosilylation inhibitor, wherein the chain length of the organopolysiloxanes crosslinker B) exceeds the chain length of the organopolysiloxanes A), and the mol ratio of Si-H groups to aliphatically unsaturated groups is at least about 2:1. A) at least one organopolysiloxane bearing on average, at least two terminal aliphatically unsaturated groups; B) at least one organopolysiloxane crosslinker bearing silicon-bonded hydrogen ("Si-H") groups, wherein no more than 67 mol percent of siloxy groups in the organopolysiloxane crosslinker contain Si-H groups, wherein at least one organopolysiloxane crosslinker (B) has the formula: where R is a C 1-20 hydrocarbon group containing no aliphatic unsaturation, c is 0, d is 3, p is from 10 to 200, and q is from 5 to 60, where the p diorganosiloxy group, and q hydrogen organosiloxy groups are distributed in any manner; C) at least one hydrosilylation catalyst; and D) optionally, a hydrosilylation inhibitor,
A sensor means or module for determining a displacement, in particular an elastic displacement, of an insert in relation to a panel , in particular a glass or glass ceramic panel, the sensor means or module and the panel forming a weighing means, in particular a scale, the sensor means or module - being adapted to be integrated in or allocated to a household appliance , in particular a cooking hob, more in particular an induction cooking hob, and - comprising or being connected to at least one processing and/or interpretation and/or compilation means, preferably for providing a particular high sensor sensitivity and/or evaluation unit accuracy characterized in that the insert is displaced or moved in relation to the panel under the weight of an item to be weighed, wherein the insert is a, preferably removable, cover part of a downdraft device or system in or allocated to the household appliance , particularly a cover part or a lid of a downdraft cooking hob. - being adapted to be integrated in or allocated to a household appliance , in particular a cooking hob, more in particular an induction cooking hob, and - comprising or being connected to at least one processing and/or interpretation and/or compilation means, preferably for providing a particular high sensor sensitivity and/or evaluation unit accuracy