An integrated optofluidic device (10; 40; 50; 100; 110) for irradiating, along an irradiation direction (Y), a fluidic sample containing an object to be analysed, the device comprising: - a block (19; 41; 51; 80; 93; 111) comprising an entry surface (17b; 41b; 51b) and being made of a material apt to transmit a light beam incident through the entry surface (17b; 41b; 51b) along an irradiation direction (Y); - a microfluidic channel (11; 42; 52; 81; 98; 112) formed as a hollow structure in the block and comprising a first flow inlet port (13; 43; 54; 82; 113) for loading a fluidic sample therein, wherein the microfluidic channel comprises a channel portion (11a; 34; 57; 89; 117) intercepting the irradiation direction (Y) and extending in a longitudinal axis (X) perpendicular to the irradiation direction, and a first flow outlet port (14; 44; 53; 83; 115) for outputting the fluidic sample configured so as to define a flow path for the fluidic sample from the first inlet port (13; 43; 54; 82; 113) to the first outlet port (14; 44; 53; 83; 115), the flow path being perpendicular to the irradiation direction (Y) in the channel portion (11a; 34; 57; 89; 117) of the microfluidic channel, and - an elongated lens cavity (12; 96, 97) for an optofluidic lens extending along a main extension axis (Z) transverse to the irradiation direction (Y) defining the lens optical axis, wherein the lens cavity is formed as a hollow structure in the block and is arranged in the block to intercept the irradiation direction between the entry surface (17b; 41b; 51b) and the microfluidic channel portion (11a; 34; 57; 89; 117), and wherein the lens cavity (12; 96, 97) is in fluid communication with a lens inlet port formed in the block (19; 41; 51; 80; 93; 111) for loading a lens fluid, wherein the lens optical axis extends perpendicularly to both the longitudinal axis (X) of the channel portion (11a; 34; 57; 89; 117) and the main extension axis (Z), and the elongated lens cavity is configured so as to form a cylindrical lens when filled by a lens fluid. - a block (19; 41; 51; 80; 93; 111) comprising an entry surface (17b; 41b; 51b) and being made of a material apt to transmit a light beam incident through the entry surface (17b; 41b; 51b) along an irradiation direction (Y); - a microfluidic channel (11; 42; 52; 81; 98; 112) formed as a hollow structure in the block and comprising a first flow inlet port (13; 43; 54; 82; 113) for loading a fluidic sample therein, wherein the microfluidic channel comprises a channel portion (11a; 34; 57; 89; 117) intercepting the irradiation direction (Y) and extending in a longitudinal axis (X) perpendicular to the irradiation direction, and a first flow outlet port (14; 44; 53; 83; 115) for outputting the fluidic sample configured so as to define a flow path for the fluidic sample from the first inlet port (13; 43; 54; 82; 113) to the first outlet port (14; 44; 53; 83; 115), the flow path being perpendicular to the irradiation direction (Y) in the channel portion (11a; 34; 57; 89; 117) of the microfluidic channel, and - an elongated lens cavity (12; 96, 97) for an optofluidic lens extending along a main extension axis (Z) transverse to the irradiation direction (Y) defining the lens optical axis, wherein the lens cavity is formed as a hollow structure in the block and is arranged in the block to intercept the irradiation direction between the entry surface (17b; 41b; 51b) and the microfluidic channel portion (11a; 34; 57; 89; 117), and wherein the lens cavity (12; 96, 97) is in fluid communication with a lens inlet port formed in the block (19; 41; 51; 80; 93; 111) for loading a lens fluid, wherein the lens optical axis extends perpendicularly to both the longitudinal axis (X) of the channel portion (11a; 34; 57; 89; 117) and the main extension axis (Z), and the elongated lens cavity is configured so as to form a cylindrical lens when filled by a lens fluid. <EOS>