mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of Formula III or a pharmaceutically acceptable ester, amide, solvate, or salt thereof, or a salt of such an ester or amide or a solvate of such an ester amide or salt, wherein: R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , and R 11 are chosen independently from hydrogen, halogen, hydroxyl, cyano, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, and C 1 -C 6 haloalkoxy; R 12 is hydrogen, C 1 -C 6 alkyl, or C 1 -C 6 haloalkyl; L 1 is -(CH 2 ) m - wherein m is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; L 2 is -(CH 2 ) n - wherein n is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; L 3 is -(CH 2 ) p - wherein p is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; and L 4 is -(CH 2 ) q - wherein q is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; and R 13 is a chelating group comprising 177 Lu, and R 13 is and R 14 is R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , and R 11 are chosen independently from hydrogen, halogen, hydroxyl, cyano, C 1 -C 6 alkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkyl, and C 1 -C 6 haloalkoxy; R 12 is hydrogen, C 1 -C 6 alkyl, or C 1 -C 6 haloalkyl; L 1 is -(CH 2 ) m - wherein m is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; L 2 is -(CH 2 ) n - wherein n is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; L 3 is -(CH 2 ) p - wherein p is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; and L 4 is -(CH 2 ) q - wherein q is an integer from 0 to 12, wherein each CH 2 can be individually replaced with -O-, -NH(CO)-, or -(CO)-NH-, providing no two adjacent CH 2 groups are replaced; and R 13 is a chelating group comprising 177 Lu, and R 13 is and R 14 is
A sheet having a tensile strength of ≥ 600 MPa determined by a tensile test using a micro dumbbell sample and a tension rate of 2 mm/min., comprising: - a carbon fiber and, disposed around a carbon monofilament constituting the carbon fiber, - a fluororesin layer, wherein a fluororesin constituting the fluororesin layer is polyvinylidene fluoride (PVdF). - a carbon fiber and, disposed around a carbon monofilament constituting the carbon fiber, - a fluororesin layer,
A water-soluble spearmint extract for use in increasing the rate of neurogenesis in a patient in need thereof, wherein the spearmint extract is in the form of a dry powder and is administered at least once a day in an amount ranging from 300 to 1200 mg, wherein said spearmint extract comprises Mentha spicata L. line KI-MsEM0110 which has been deposited with ATCC and assigned accession number PTA-122652 and/or Mentha spicata L. line KI-MsEM0042 which has been deposited with ATCC and assigned accession number PTA-122651.
A nursing bed with a dimension in a longitudinal direction and a dimension in a width direction, comprising: an upper surface forming member which forms a bed upper surface on which a care receiver lies; and a driving mechanism configured to move at least a portion of the upper surface forming member , wherein the bed upper surface includes a curved surface which is curved downwardly in the width direction, characterized in that the driving mechanism is configured so that a rotational driving force is transmitted from a rotational driver mounted on a distal end portion of a robot arm , and wherein the driving mechanism has a plurality of rotated drivers which are selectively and separatably connected to the rotational driver , the plurality of rotated drivers being respectively installed corresponding to mutually different moving motions in the upper surface forming member . an upper surface forming member which forms a bed upper surface on which a care receiver lies; and a driving mechanism configured to move at least a portion of the upper surface forming member , wherein the bed upper surface includes a curved surface which is curved downwardly in the width direction, characterized in that the driving mechanism is configured so that a rotational driving force is transmitted from a rotational driver mounted on a distal end portion of a robot arm , and wherein the driving mechanism has a plurality of rotated drivers which are selectively and separatably connected to the rotational driver , the plurality of rotated drivers being respectively installed corresponding to mutually different moving motions in the upper surface forming member .
A process for making food granules comprising a lipid, salt, starch, a hygroscopic food material and optionally dry spices, the process comprising the steps of: a) coating the hygroscopic food material with the lipid or part of the lipid; b) mixing the coated hygroscopic food material with the salt, the starch and optionally the dry spices; c) adjusting the moisture content of the mixture of step b) to a water content of 7 - 13 wt% (wet weight) by adding water and/or an aqueous composition to result in a wet mass; d) cold extruding the wet mass through a sieve into granules at a temperature below 35°C ; e) drying the granules to a moisture content of 1 - 7 wt% (wet weight). a) coating the hygroscopic food material with the lipid or part of the lipid; b) mixing the coated hygroscopic food material with the salt, the starch and optionally the dry spices; c) adjusting the moisture content of the mixture of step b) to a water content of 7 - 13 wt% (wet weight) by adding water and/or an aqueous composition to result in a wet mass; d) cold extruding the wet mass through a sieve into granules at a temperature below 35°C ; e) drying the granules to a moisture content of 1 - 7 wt% (wet weight).
An embossed composite material, comprising: a polyurethane layer; an un-clickable foam layer having a top surface and an opposite bottom surface, wherein said top surface is bonded to said polyurethane layer; a backing that is bonded to said bottom surface of said un-clickable foam layer, wherein said polyurethane layer, said un-clickable foam layer and said backing each has an emboss pattern forming pillow-like cells, and wherein said pillow-like cells are delimited by emboss protuberances and emboss lines formed by said emboss pattern. a polyurethane layer; an un-clickable foam layer having a top surface and an opposite bottom surface, wherein said top surface is bonded to said polyurethane layer; a backing that is bonded to said bottom surface of said un-clickable foam layer, wherein said polyurethane layer, said un-clickable foam layer and said backing each has an emboss pattern forming pillow-like cells, and wherein said pillow-like cells are delimited by emboss protuberances and emboss lines formed by said emboss pattern.
A hair styling device (10; 210) for imparting a wave to a section of hair without clamping the section of hair in the wave form, the device having a first forming member and a second forming member comprising a first pair of neighbouring forming members, a first hair-receiving region between the first forming member and the second forming member, the device having a second pair of neighbouring forming members with a second hair-receiving region between the second pair of neighbouring forming members, the device having multiple driving members (20; 120) including at least a first driving member and a second driving member (20; 120), the first driving member being movable relative to the first forming member and the second forming member to deform the section of hair in the first hair-receiving region in use, the second driving member being movable relative to the second pair of neighbouring forming members to deform the section of hair in the second hair-receiving region in use, the first and second driving members (20; 120) undertaking a two-stage movement as they deform the section of hair, the driving members in a first stage being movable in a first direction (D1) to drive the section of hair into the respective hair-receiving region in use, the driving members (20; 120) in a second stage being movable in a second direction (D2), the second direction being at an angle to the first direction whereby in use to further move the section of hair in the respective hair-receiving region .
A process to produce a mono vinyl thioether by reacting acetylene with a compound comprising one thiol group and one hydroxy group, hereinafter referred to as thiol-hydroxy compound, wherein the reaction is performed at a pressure below 2 bars.
A non-anesthetic protective gas and a liquid anesthetic agent for use in a method of providing anesthesia and organ-protection to a subject in need thereof, said method comprising co-administering to the subject the non-anesthetic protective gas in an amount effective to provide organ protection, and the liquid anesthetic agent in an amount effective to provide anesthesia, at normobaric conditions, and wherein the non-anesthetic protective gas is argon.
A method of operating a fault detection unit to identify a fault condition in a digital subscriber line in a telecommunications network , said digital subscriber line comprising metallic wires, and said method comprising: determining an upstream line attenuation and a downstream line attenuation associated with the digital subscriber line; calculating a line attenuation ratio for said digital subscriber line based on the downstream and upstream line attenuations; comparing the calculated line attenuation ratio to the line attenuation ratio distribution calculated from a population of digital subscriber lines, and each of said population of digital subscriber lines comprises metallic wires; determining a fault condition of the digital subscriber line in dependence on the result of the comparison; characterised in that the line attenuation ratio distribution comprises an upper threshold of attenuation ratio and a lower threshold of attenuation ratio, said upper and lower thresholds defining a range of attenuation ratios within which a proportion of the population of digital subscriber lines reside, and the determined fault condition is either a high resistance connection if the calculated line attenuation ratio is below the lower threshold and a shunt if the calculated line attenuation ratio is above the upper threshold. determining an upstream line attenuation and a downstream line attenuation associated with the digital subscriber line; calculating a line attenuation ratio for said digital subscriber line based on the downstream and upstream line attenuations; comparing the calculated line attenuation ratio to the line attenuation ratio distribution calculated from a population of digital subscriber lines, and each of said population of digital subscriber lines comprises metallic wires; determining a fault condition of the digital subscriber line in dependence on the result of the comparison; characterised in that the line attenuation ratio distribution comprises an upper threshold of attenuation ratio and a lower threshold of attenuation ratio, said upper and lower thresholds defining a range of attenuation ratios within which a proportion of the population of digital subscriber lines reside, and the determined fault condition is either a high resistance connection if the calculated line attenuation ratio is below the lower threshold and a shunt if the calculated line attenuation ratio is above the upper threshold.
An acoustical assembly adapted to be inserted into an ear canal, said acoustical assembly comprising - a receiver unit adapted to generate sound pressure waves, - a microphone unit adapted to detect sound pressure waves inside the ear canal when the acoustical assembly is inserted in the ear canal, and - a nozzle comprising a receiver unit mount adapted to house at least part of the receiver unit , wherein the nozzle comprises at least one sound channel adapted to guide generated sound pressure waves from a receiver unit outlet opening to at least one sound outlet opening of the nozzle , wherein the nozzle further comprises a microphone unit mount adapted to house at least part of the microphone unit , characterised in that the microphone unit is arranged in the microphone unit mount in such a way that a sound inlet opening of the microphone unit is not oriented towards the ear drum when the acoustical assembly is inserted in the ear canal. - a receiver unit adapted to generate sound pressure waves, - a microphone unit adapted to detect sound pressure waves inside the ear canal when the acoustical assembly is inserted in the ear canal, and - a nozzle comprising a receiver unit mount adapted to house at least part of the receiver unit , wherein the nozzle comprises at least one sound channel adapted to guide generated sound pressure waves from a receiver unit outlet opening to at least one sound outlet opening of the nozzle ,
A valve system for an engine having an engine block, the valve system comprising two coaxially mounted cams each having a respective follower , a summation lever coupled to the followers of both cams so as to be movable in proportion to the sum of the instantaneous lifts of the respective cams, and a valve actuating rocker pivotably coupled to the summation lever and operative to displace an engine valve in dependence upon the movement of the summation lever , wherein the actuating rocker rests on a hydraulic lash adjuster , and wherein a control spring is provided to urge the summation lever in a direction to compress the hydraulic lash adjuster , a stop being provided to limit expansion of the control spring , characterised in that the control spring acts on the summation lever by way of a plunger ('42) that is constrained to reciprocate linearly within a bore that is stationary relative to the engine block and an end of the plunger ('42) is in sliding engagement with the summation lever , whereby a point of contact between the plunger ('42) and the summation rocker is displaced in a direction transverse to the axis of the plunger during pivoting movement of the summation lever , and the plunger ('42) has a shoulder ('46) at a predetermined distance from the end in sliding engagement with the summation lever , the shoulder ('46) contacting an abutment surface ('48) that is stationary relative to the engine block to limit the displacement of the plunger ('42) in a direction to compress the lash adjuster.
A resin component comprising: a curable resin; and nanoparticles dispersed in the resin, the nanoparticles each independently comprising surface-bonded hydrophobically-modifying (C 1 -C 50 )hydrocarbyl groups, wherein at least one of the (C 1 -C 50 )hydrocarbyl groups is a (C 1 -C 50 )alkyl group and at least one of the surface-bonded hydrophobically-modifying (C 1 -C 50 )hydrocarbyl groups is a (C 6 -C 50 )aryl group. a curable resin; and nanoparticles dispersed in the resin, the nanoparticles each independently comprising surface-bonded hydrophobically-modifying (C 1 -C 50 )hydrocarbyl groups, wherein at least one of the (C 1 -C 50 )hydrocarbyl groups is a (C 1 -C 50 )alkyl group and at least one of the surface-bonded hydrophobically-modifying (C 1 -C 50 )hydrocarbyl groups is a (C 6 -C 50 )aryl group.
A method for the automated application of labels successively from a backing layer onto successive articles , said method comprising feeding a supply of labels defined by a first sheet material , which is adhered to the backing layer of sheet material , towards an application point , said labels in said supply of labels joined to adjacent labels in the supply by a line of weakening and a first, leading, label is connected to a following label (8") by a line of weakening , and lines of weakening are provided between successive labels, advancing the label supply and backing layer towards the application point and to apply the leading label to a said article the backing layer is detached from a leading portion of the leading label and said leading portion is applied to the said article and the strength of the line of weakening is provided to be such that the line of weakening between the first, leading label and the following label (8") remains intact until the remainder of the leading label is released from the backing layer , characterised in that the retention strength of the said lines of weakening is greater than the adhesive strength of the attachment of the first sheet material to the backing layer sheet material such that the force required to break the line of weakening is greater than the force required to detach the first sheet material from the backing layer sheet material .
A brazed superabrasive assembly , comprising: a superabrasive layer ; a stress relieving layer coupled to the superabrasive layer by a first braze layer ; and a substrate coupled to the stress relieving layer by a last braze layer ; wherein the stress relieving layer has a solidus or melting temperature that is greater than a solidus temperature of the first braze layer and the last braze layer ; characterised in that : the first braze layer comprises Ag, Cu and Ti, the stress relieving layer comprises Cu, and the last braze layer comprises Ag and Cu, wherein the first braze layer , the stress relieving layer , and the last braze layer was, prior to brazing, a pre-brazed assembly having the following layers in sequence: an Ag-Cu braze alloy as the first braze layer ; a Ti layer as a second layer; a Ag-Cu braze alloy as a third layer; the stress relieving layer being a Cu layer as a fourth layer; and a Ag-Cu braze alloy as the last braze layer . a superabrasive layer ; a stress relieving layer coupled to the superabrasive layer by a first braze layer ; and a substrate coupled to the stress relieving layer by a last braze layer ; wherein the stress relieving layer has a solidus or melting temperature that is greater than a solidus temperature of the first braze layer and the last braze layer ; characterised in that : the first braze layer comprises Ag, Cu and Ti, the stress relieving layer comprises Cu, and the last braze layer comprises Ag and Cu, wherein the first braze layer , the stress relieving layer , and the last braze layer was, prior to brazing, a pre-brazed assembly having the following layers in sequence: an Ag-Cu braze alloy as the first braze layer ; a Ti layer as a second layer; a Ag-Cu braze alloy as a third layer; the stress relieving layer being a Cu layer as a fourth layer; and a Ag-Cu braze alloy as the last braze layer . an Ag-Cu braze alloy as the first braze layer ; a Ti layer as a second layer; a Ag-Cu braze alloy as a third layer; the stress relieving layer being a Cu layer as a fourth layer; and
A liquid, highly concentrated, stable pharmaceutical anti-HER2 antibody formulation of a pharmaceutically active anti-HER2 antibody for subcutaneous injection comprising: a. about 50 to 350 mg/ml anti-HER2 antibody; b. about 1 to 100 mM of a buffering agent providing a pH of 5.5 ± 2.0; c. about 1 to 500 mM of a stabilizer or a mixture of two or more stabilizers; d. about 0.01 to 0.08 % (w/v) of a nonionic surfactant; and e. about 1500 to about 12000 U/ml of a hyaluronidase enzyme, wherein the term "about" means variations of +/- 10% of the specific value. a. about 50 to 350 mg/ml anti-HER2 antibody; b. about 1 to 100 mM of a buffering agent providing a pH of 5.5 ± 2.0; c. about 1 to 500 mM of a stabilizer or a mixture of two or more stabilizers; d. about 0.01 to 0.08 % (w/v) of a nonionic surfactant; and e. about 1500 to about 12000 U/ml of a hyaluronidase enzyme, wherein the term "about" means variations of +/- 10% of the specific value.
Apparatus for washing contaminated aggregate comprising: at least one channel arranged in use to receive a liquid containing contaminated aggregate, the channel having a base comprising agitators spaced along the length of the channel; and characterized by a plurality of jets spaced along the length of the channel for directing pressurised fluid at the contaminated aggregate in order to agitate the contaminated aggregate thereby promoting separation of aggregate from debris and/or contaminate and urging the aggregate over and against the agitators and through the channel(s) .
A composition comprising a heat transfer portion and a lubricant portion comprising a compound of formula (I): wherein W is independently selected from the group consisting of H, F, Cl, Br and I; X is independently selected from the group consisting of H, F, Cl, Br, I, CW 3 and OR on the basis that at least one X is OR; R is independently selected from the group consisting of C(O)(CH 2 ) m (CF 2 ) n Y and CW 2 C(CW 2 OC(O)(CH 2 ) m (CF 2 ) n Y) 3 ; m is an integer from 0 to 2; n is an integer from 2 to 8; Y is C(Z) 3 ; and Z is independently selected from the group consisting of H, F, Cl, Br and I; wherein the heat transfer portion comprises one or more compounds selected from the group consisting of (hydro)fluoroolefins (HFOs), hydrofluorocarbons (HFCs), chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), propane, propylene, n-butane and isobutane . W is independently selected from the group consisting of H, F, Cl, Br and I; X is independently selected from the group consisting of H, F, Cl, Br, I, CW 3 and OR on the basis that at least one X is OR; R is independently selected from the group consisting of C(O)(CH 2 ) m (CF 2 ) n Y and CW 2 C(CW 2 OC(O)(CH 2 ) m (CF 2 ) n Y) 3 ; m is an integer from 0 to 2; n is an integer from 2 to 8; Y is C(Z) 3 ; and Z is independently selected from the group consisting of H, F, Cl, Br and I; wherein the heat transfer portion comprises one or more compounds selected from the group consisting of (hydro)fluoroolefins (HFOs), hydrofluorocarbons (HFCs), chlorofluorocarbons (CFCs), hydrochlorofluorocarbons (HCFCs), propane, propylene, n-butane and isobutane .