mhurhangee/patent-ind-claim-en huggingface dataset:
A method for determining a location of a target nucleic acid in a biological sample, the method comprising: (a) providing the biological sample placed on a first substrate; (b) contacting a plurality of first probes and second probes to the biological sample, wherein the plurality of first probes and second probes target a plurality of nucleic acids in the biological sample and wherein a first probe and a second probe of the plurality comprise sequences that are substantially complementary to sequences that are not adjacent to each other on the target nucleic acid, and wherein the second probe comprises a capture probe capture domain sequence that is complementary to all or a portion of a capture domain of a capture probe; (c) hybridizing the first probe and the second probe to the target nucleic acid; (d) generating a ligation product by ligating the first probe and the second probe; (e) releasing the ligation product from the target nucleic acid; (f) hybridizing the ligation product to the capture domain of the capture probe affixed on an array, wherein the capture probe further comprises a spatial barcode; and (g) determining (i) all or part of the sequence of the ligation product bound to the capture domain, or a complement thereof, and (ii) the sequence of the spatial barcode, or a complement thereof, and using the determined sequences of (i) and (ii) to determine the location of the target nucleic acid in the biological sample. (a) providing the biological sample placed on a first substrate; (b) contacting a plurality of first probes and second probes to the biological sample, wherein the plurality of first probes and second probes target a plurality of nucleic acids in the biological sample and wherein a first probe and a second probe of the plurality comprise sequences that are substantially complementary to sequences that are not adjacent to each other on the target nucleic acid, and wherein the second probe comprises a capture probe capture domain sequence that is complementary to all or a portion of a capture domain of a capture probe; (c) hybridizing the first probe and the second probe to the target nucleic acid; (d) generating a ligation product by ligating the first probe and the second probe; (e) releasing the ligation product from the target nucleic acid; (f) hybridizing the ligation product to the capture domain of the capture probe affixed on an array, wherein the capture probe further comprises a spatial barcode; and (g) determining (i) all or part of the sequence of the ligation product bound to the capture domain, or a complement thereof, and (ii) the sequence of the spatial barcode, or a complement thereof, and using the determined sequences of (i) and (ii) to determine the location of the target nucleic acid in the biological sample.
A bearing steel part comprising, in terms of % by mass: C: 0.76 to 1.20%, Si: 0.70 to 3.00%, Mn: 0.10 to 2.00%, Cr: 0.10 to 3.00%, Mo: 0.001 to 0.100%, S: 0.001 to 0.030%, N: 0.004 to 0.020%, Ca: 0.0002 to 0.0100%, Al: 0.001 to 0.010%, O: 0 to 0.005%, P: 0 to 0.030%, Ni: 0 to 3.00%, Cu: 0 to 1.00%, Co: 0 to 3.00%, W: 0 to 1.00%, V: 0 to 0.30%, Ti: 0 to 0.300%, Nb: 0 to 0.300%, B: 0 to 0.0050% Pb: 0 to 0.50%, Bi: 0 to 0.50%, Mg: 0 to 0.0100%, Zr: 0 to 0.0500%, Te: 0 to 0.1000%, rare earth elements: 0 to 0.0050%, Sn: 0 to 2.0%, In: 0 to 0.50%, and a balance consisting of Fe and impurities, wherein a number density of oxide particles, which have an equivalent circle diameter of 5 μm or more, and comprise CaO, Al 2 O 3 and SiO 2 , such that a content ratio of Al 2 O 3 with respect to a total mass of CaO, Al 2 O 3 , and SiO 2 is 50% by mass or more, is 3.0/cm 2 or less in an arbitrary cross-section of the part, wherein a Vickers hardness at a depth of 50 μm from a rolling surface is 750 or more, and wherein a compressive residual stress at the rolling surface is 900 MPa or more, wherein the number density is determined according to the description. C: 0.76 to 1.20%, Si: 0.70 to 3.00%, Mn: 0.10 to 2.00%, Cr: 0.10 to 3.00%, Mo: 0.001 to 0.100%, S: 0.001 to 0.030%, N: 0.004 to 0.020%, Ca: 0.0002 to 0.0100%, Al: 0.001 to 0.010%, O: 0 to 0.005%, P: 0 to 0.030%, Ni: 0 to 3.00%, Cu: 0 to 1.00%, Co: 0 to 3.00%, W: 0 to 1.00%, V: 0 to 0.30%, Ti: 0 to 0.300%, Nb: 0 to 0.300%, B: 0 to 0.0050% Pb: 0 to 0.50%, Bi: 0 to 0.50%, Mg: 0 to 0.0100%, Zr: 0 to 0.0500%, Te: 0 to 0.1000%, rare earth elements: 0 to 0.0050%, Sn: 0 to 2.0%, In: 0 to 0.50%, and a balance consisting of Fe and impurities, wherein a number density of oxide particles, which have an equivalent circle diameter of 5 μm or more, and comprise CaO, Al 2 O 3 and SiO 2 , such that a content ratio of Al 2 O 3 with respect to a total mass of CaO, Al 2 O 3 , and SiO 2 is 50% by mass or more, is 3.0/cm 2 or less in an arbitrary cross-section of the part, wherein a Vickers hardness at a depth of 50 μm from a rolling surface is 750 or more, and wherein a compressive residual stress at the rolling surface is 900 MPa or more, wherein the number density is determined according to the description.
An inkjet recording apparatus, comprising: an ink container that is adapted to store an ink for printing on a printing object ; a magnetic stirring bar disposed in the ink container ; and a stirring mechanism that is adapted to stir the ink stored in the ink container , wherein the stirring mechanism includes a stationary shaft and a rotating body that is adapted to rotate around the stationary shaft , the rotating body is adapted to spin in tandem with the magnetic stirring bar , and the stationary shaft and the rotating body are disposed under the ink container . an ink container that is adapted to store an ink for printing on a printing object ; a magnetic stirring bar disposed in the ink container ; and a stirring mechanism that is adapted to stir the ink stored in the ink container , wherein the stirring mechanism includes a stationary shaft and a rotating body that is adapted to rotate around the stationary shaft , the rotating body is adapted to spin in tandem with the magnetic stirring bar , and the stationary shaft and the rotating body are disposed under the ink container . the stirring mechanism includes a stationary shaft and a rotating body that is adapted to rotate around the stationary shaft , the rotating body is adapted to spin in tandem with the magnetic stirring bar , and the stationary shaft and the rotating body are disposed under the ink container .
A dry sprinkler comprising: a fluid conduit that is configured to couple to a fluid supply, the conduit having a first end and a second end ; a valve that is positioned proximate to the first end of the conduit , the valve having (i) a closed state that prevents fluid from the fluid supply from flowing through the conduit , and (ii) an open state that allows fluid from the fluid supply to flow through the conduit ; a fire sprinkler head positioned proximate to the second end of the conduit , the fire sprinkler head having a thermally responsive element that reacts to an elevated temperature condition; an unbiased tie positioned within the conduit and being operably coupled to the valve and the thermally responsive element, the unbiased tie having at least an unengaged state and an engaged state and; a sheath member that is located within the conduit and surrounds the unbiased tie over most of its length; wherein (i) the unbiased tie is not biased towards the sprinkler head in the unengaged state, (ii) the reaction of the thermally responsive element to the elevated temperature condition causes the tie to change from the unengaged state to the engaged state, and (iii) changing the tie to the engaged state from the unengaged state allows the valve to change from the closed state to the open state; wherein the tie is flexible. a fluid conduit that is configured to couple to a fluid supply, the conduit having a first end and a second end ; a valve that is positioned proximate to the first end of the conduit , the valve having (i) a closed state that prevents fluid from the fluid supply from flowing through the conduit , and (ii) an open state that allows fluid from the fluid supply to flow through the conduit ; a fire sprinkler head positioned proximate to the second end of the conduit , the fire sprinkler head having a thermally responsive element that reacts to an elevated temperature condition; an unbiased tie positioned within the conduit and being operably coupled to the valve and the thermally responsive element, the unbiased tie having at least an unengaged state and an engaged state and; a sheath member that is located within the conduit and surrounds the unbiased tie over most of its length; wherein (i) the unbiased tie is not biased towards the sprinkler head in the unengaged state, (ii) the reaction of the thermally responsive element to the elevated temperature condition causes the tie to change from the unengaged state to the engaged state, and (iii) changing the tie to the engaged state from the unengaged state allows the valve to change from the closed state to the open state; wherein the tie is flexible.
A vane for a gas turbine engine , comprising: a purge flow interface that comprises a pocket located in communication with a feather seal slot in a mateface , the pocket having a cross sectional shape larger than that of the feather seal slot , wherein the pocket is contoured with respect to a gas path surface ; and a multiple of passages in communication with the pocket , wherein an entry to each of the multiple of passages receives a portion of a cooling airflow (S) that is also communicated into an airfoil . a purge flow interface that comprises a pocket located in communication with a feather seal slot in a mateface , the pocket having a cross sectional shape larger than that of the feather seal slot , wherein the pocket is contoured with respect to a gas path surface ; and a multiple of passages in communication with the pocket , wherein an entry to each of the multiple of passages receives a portion of a cooling airflow (S) that is also communicated into an airfoil .
An aqueous bleach-free cleaning composition comprising: (i) 1.5 to 5 % by weight surfactant system containing a. a first surfactant which is a linear alkyl benzene sulphonate; and b. a second surfactant which is an alkoxylated sulphate or a mixture of alkoxylated sulphate and up to 0.4 % by weight of non-ionic surfactant, the non-ionic surfactant having a HLB of 10 to 15; (ii) a non-phosphate alkaline builder in an amount sufficient to provide pH of 11 to 14 to said composition; and, (iii) 2 to 5 % by weight electrolyte which is a salt of a strong acid and a strong base and wherein said salt is at least once of sodium chloride, sodium nitrate, sodium sulphate, potassium chloride, potassium nitrate or potassium sulphate; wherein ratio of amount of said first surfactant to that of said second surfactant is 1:1 to 1:6.5 parts by weight, wherein the second surfactant keeps the first surfactant in micellar phase, and where viscosity of said composition is 250 to 2500 cP at 20 s -1 (0.25 Pa.s to 2.5 Pa.s) at 20 °C wherein bleach-free is defined as the composition comprising cumulatively less than 1 % by weight of bleaching ingredients. (i) 1.5 to 5 % by weight surfactant system containing a. a first surfactant which is a linear alkyl benzene sulphonate; and b. a second surfactant which is an alkoxylated sulphate or a mixture of alkoxylated sulphate and up to 0.4 % by weight of non-ionic surfactant, the non-ionic surfactant having a HLB of 10 to 15; a. a first surfactant which is a linear alkyl benzene sulphonate; and b. a second surfactant which is an alkoxylated sulphate or a mixture of alkoxylated sulphate and up to 0.4 % by weight of non-ionic surfactant, the non-ionic surfactant having a HLB of 10 to 15; (ii) a non-phosphate alkaline builder in an amount sufficient to provide pH of 11 to 14 to said composition; and, (iii) 2 to 5 % by weight electrolyte which is a salt of a strong acid and a strong base and wherein said salt is at least once of sodium chloride, sodium nitrate, sodium sulphate, potassium chloride, potassium nitrate or potassium sulphate;
A side airbag for installation in a motor vehicle to provide protection to an associated vehicle occupant, the side airbag comprising: an outer skin forming a single inflatable chamber having both an upper thorax portion adapted for contact with a thorax region of the associated vehicle occupant and a lower pelvic portion adapted for contact with a pelvic region of the associated vehicle occupant, and a loop diffuser adapted for placement about an inflator disposed at least in part within the inflatable chamber, wherein the loop diffuser has a truncated triangular outline in a flattened condition and has a truncated cone shape during inflation of the inflatable chamber with opposed small and large open ends of the truncated cone shape being offset and open relative to the upper side of the thorax region of the single inflatable chamber and the lower side of the pelvic portion of the single inflatable chamber respectively, wherein the small open end is adapted to permit communication of inflation gas from the inflator to the upper thorax portion of the inflatable chamber and the large open end is adapted to permit communication of inflation gas from the inflator to the lower pelvic portion of the inflatable chamber, wherein a cross sectional open area of the small open end is less than 10% of a cross sectional open area of the large open end . an outer skin forming a single inflatable chamber having both an upper thorax portion adapted for contact with a thorax region of the associated vehicle occupant and a lower pelvic portion adapted for contact with a pelvic region of the associated vehicle occupant, and a loop diffuser adapted for placement about an inflator disposed at least in part within the inflatable chamber, wherein the loop diffuser has a truncated triangular outline in a flattened condition and has a truncated cone shape during inflation of the inflatable chamber with opposed small and large open ends of the truncated cone shape being offset and open relative to the upper side of the thorax region of the single inflatable chamber and the lower side of the pelvic portion of the single inflatable chamber respectively, wherein the small open end is adapted to permit communication of inflation gas from the inflator to the upper thorax portion of the inflatable chamber and the large open end is adapted to permit communication of inflation gas from the inflator to the lower pelvic portion of the inflatable chamber, wherein a cross sectional open area of the small open end is less than 10% of a cross sectional open area of the large open end .
A method for controlling a polyimide backbone structure, comprising: in preparation of a polyimide through reaction of a diamine component and -cyclohexanetetracarboxylic dianhydride in an organic solvent containing an aprotic amide solvent and a lactone solvent, keeping a mass ratio of the aprotic amide solvent and the lactone solvent ((aprotic amide solvent):(lactone solvent)) constant within a range of from 30:70 to 80:20, so as to convert a cis-structure derived from the -cyclohexanetetracarboxylic dianhydride in the formed polyimide to a trans-structure derived from -cyclohexanetetracarboxylic dianhydride corresponding to the reaction conditions, thereby controlling a proportion of the trans-structure.
Device for sintering a workpiece with an induction furnace, in which the workpiece and where applicable additives - directly or indirectly - can be inductively heated, characterised in that the induction furnace is constructed as a heating module , in that an introduction module for introducing the workpiece is arranged directly or indirectly upstream of the heating module and a cooling module for cooling the workpiece is arranged directly or indirectly downstream of the heating module and in that the device as a result of the releasability of the connections of the modules with each other is prepared, by exchanging adjacent modules, to arrange them at any angle with respect to each other and thus to adapt them to any desired spatial requirements and workpiece shapes.
Motor vehicle comprising an operating unit being arranged in said motor vehicle, wherein the operating unit is located below an elastic cover and the operation unit is designed such that it can be folded up from an at least approximately horizontal position, characterized in that the operating unit comprises a touch-sensitive operating panel ; and in that the operating unit is designed as a conveyor belt or integrated into a conveyor belt allowing the operating panel to have a displaced position. the operating unit comprises a touch-sensitive operating panel ; and in that the operating unit is designed as a conveyor belt or integrated into a conveyor belt allowing the operating panel to have a displaced position.
A method of prenatal screening for a recessive disorder and/or a disorder caused by a point mutation comprising: (a) amplifying a region encompassing the site of a mutation responsible for the disorder, the amplification being performed on a DNA sample obtained from a pregnant female which comprises both maternal and fetal DNA; and (b) sequencing a plurality of products from the amplification and determining whether or not the mutant allele is represented at a different frequency to that expected from the genotype of the pregnant female alone, wherein the amplification is performed by a two-step PCR, where the first step amplifies the amplicon of interest and the second step introduces additional sequences not present in the template. (a) amplifying a region encompassing the site of a mutation responsible for the disorder, the amplification being performed on a DNA sample obtained from a pregnant female which comprises both maternal and fetal DNA; and (b) sequencing a plurality of products from the amplification and determining whether or not the mutant allele is represented at a different frequency to that expected from the genotype of the pregnant female alone, wherein the amplification is performed by a two-step PCR, where the first step amplifies the amplicon of interest and the second step introduces additional sequences not present in the template.
A method for the surface oxidation of carbon black, the method comprising continuously mixing: a solution or slurry of the carbon black in an organic or other solvent with a liquid carrier containing a reagent for surface oxidation of the carbon black in a counter current mixing reactor whereby to obtain reaction of the carbon black with the reagent and the formation of a surface oxidised carbon black as a dispersion of nanoparticles in the liquid carrier and solvent mixture.
A probing apparatus arranged for detection of an electric signal generated by a device-under-test by tapping the electric signal from a connector on the device-under-test when the probing apparatus is applied on the device-under-test , the probing apparatus comprising: - a rigid support structure , - a probing instrument fixed to the support structure and being adapted to contact the connector for tapping the electric signal, and - at least two magnets fixed to the support structure , each magnet being adapted to apply attracting force on a mating metal element on the device-under-test such that the probing instrument can be aligned to contact the connector , characterized in that the rigid support structure has a contact surface adapted for sliding contact with the device-under-test , the magnets are configured such that a gap is formed between each magnet and mating metal element when said contact surface touches the device-under-test , wherein the contact surface on the support structure is adapted to allow a lateral movement by touching and sliding against a contact surface on the device-under-test so as to align the probing instrument to the connector , and wherein each magnet's position relative the support structure when in use is adjustable for regulating said gap so as to control the attracting force on the mating metal element . - a rigid support structure , - a probing instrument fixed to the support structure and being adapted to contact the connector for tapping the electric signal, and - at least two magnets fixed to the support structure , each magnet being adapted to apply attracting force on a mating metal element on the device-under-test such that the probing instrument can be aligned to contact the connector ,
A computer-implemented method of supporting a roaming note-taking application feature, the method comprising: operating, by a user (110-118), a note-taking application by way of interactions with a first user computing device (120-128) or a second user computing device (130-138), wherein the interactions involve storage and retrieval of content relative to a centralized database (104; 310), wherein the content comprises notes, wherein the centralized database (104; 310) includes a collection of application data that is a record of application configuration variables and settings, wherein the collection of application data includes a collection of custom tag data , the collection of custom tag data comprising at least one record selected from the group consisting of a record of a tag modification, a record of a tag application, and a record of a tag removal, wherein the user is enabled to selectively associate a tag with a note and then perform a search on a tag specific basis, wherein when a particular tag of the tag data is applied to a particular note utilizing the note-taking application at the first user computing device, said particular note surfaces when a search is subsequently conducted based on said particular tag utilizing the second user computing device (130-138).
A frame supporting structure for a commercial vehicle, preferably a lorry, in particular a semitrailer tractor, having: - a first longitudinally extending supporting construction and a second longitudinally extending supporting construction which are spaced apart from one another in the transverse direction (QR) of the frame supporting structure , and - two wheel suspensions (RA) for front wheels (Rv) of the commercial vehicle, in particular two wheel suspensions (RA) preferably having spring and/or damper elements, wherein - the frame supporting structure comprises a damper support (DT) which interconnects the two wheel suspensions (RA) and/or serves to take up forces from the two wheel suspensions (RA), characterized in that - the frame supporting structure comprises a third longitudinally extending supporting construction which extends between the first supporting construction and the second supporting construction ; and/or - the first supporting construction and the second supporting construction are routed laterally inwards in order to form a narrowed supporting structure , wherein the damper support (DT) extends over the narrowed supporting structure . - a first longitudinally extending supporting construction and a second longitudinally extending supporting construction which are spaced apart from one another in the transverse direction (QR) of the frame supporting structure , and - two wheel suspensions (RA) for front wheels (Rv) of the commercial vehicle, in particular two wheel suspensions (RA) preferably having spring and/or damper elements, - the frame supporting structure comprises a damper support (DT) which interconnects the two wheel suspensions (RA) and/or serves to take up forces from the two wheel suspensions (RA), - the frame supporting structure comprises a third longitudinally extending supporting construction which extends between the first supporting construction and the second supporting construction ; and/or - the first supporting construction and the second supporting construction are routed laterally inwards in order to form a narrowed supporting structure , wherein the damper support (DT) extends over the narrowed supporting structure .