mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of the formula: or a pharmaceutically acceptable salt thereof, wherein Y 2 is selected from N and C-R y2 ; Z 2 is selected from N and C-R z2 ; Z 4 is selected from N and C-R z4 ; R † is independently selected from hydrogen and C 1-6 aliphatic optionally substituted with -OR, - C(O)N(R) 2 , or -C(O)OR; R y1 , R y2 , R z2 , R z1 and R z4 are independently selected from hydrogen, halogen, -CN, -OR, - C(O)OR, and C 1-6 aliphatic optionally substituted with halogen, -CN, -OR, -N(R) 2 , -C(O)OR, or -C(O)N(R) 2 ; and each R is independently selected from hydrogen and C 1-6 aliphatic, or two instances of R, together with the atom to which they are attached, form a 3- to 6-membered saturated or partially unsaturated heterocyclic ring, for use in the treatment or prevention of axonal degeneration. or a pharmaceutically acceptable salt thereof, wherein Y 2 is selected from N and C-R y2 ; Z 2 is selected from N and C-R z2 ; Z 4 is selected from N and C-R z4 ; R † is independently selected from hydrogen and C 1-6 aliphatic optionally substituted with -OR, - C(O)N(R) 2 , or -C(O)OR; R y1 , R y2 , R z2 , R z1 and R z4 are independently selected from hydrogen, halogen, -CN, -OR, - C(O)OR, and C 1-6 aliphatic optionally substituted with halogen, -CN, -OR, -N(R) 2 , -C(O)OR, or -C(O)N(R) 2 ; and each R is independently selected from hydrogen and C 1-6 aliphatic, or two instances of R, together with the atom to which they are attached, form a 3- to 6-membered saturated or partially unsaturated heterocyclic ring, for use in the treatment or prevention of axonal degeneration.
A condition monitoring system for monitoring a condition of equipment configuring a wind turbine, the wind turbine including a nacelle rotatably supported on a top of a tower and being rotatable about the center axis of the tower, the condition monitoring system comprising: a first detector configured to detect the condition of the equipment; a monitor device configured to generate a diagnosis parameter based on a detection result of the first detector; a controller configured to diagnose a failure of the equipment based on the diagnosis parameter; and a second detector configured to detect a rotation speed of the nacelle about the center axis, the controller being configured to diagnose whether the equipment has a failure by correcting the diagnosis parameter based on a detection result of the second detector and comparing the corrected diagnosis parameter with a predetermined threshold value. a first detector configured to detect the condition of the equipment; a monitor device configured to generate a diagnosis parameter based on a detection result of the first detector; a controller configured to diagnose a failure of the equipment based on the diagnosis parameter; and a second detector configured to detect a rotation speed of the nacelle about the center axis, the controller being configured to diagnose whether the equipment has a failure by correcting the diagnosis parameter based on a detection result of the second detector and comparing the corrected diagnosis parameter with a predetermined threshold value.
A zipper tape comprising: a pair of belt-shaped bases comprising a first belt-shaped base and a second belt-shaped base each configured to be bonded to a film of a bag body ; and an engagement portion comprising a mutually engageable first engagement portion and second engagement portion , the first and second engagement portions being provided integrally with the first and second belt-shaped bases, respectively, wherein the first belt-shaped base comprises at least two portions comprising a first portion (S1) exhibiting a first bonding strength and a second portion (S2) exhibiting a second bonding strength different from the first bonding strength when the zipper tape is bonded to the film , the first bonding strength of the first portion (SI) to the film being larger than the second bonding strength of the second portion (S2) to the film (11 A, 11B), characterized in that the at least two portions (S1, S2) are provided on a first side of the first belt-shaped base opposite a second side of the first belt-shaped base provided with the first engagement portion and between a point at which the first engagement portion is provided and an edge in a width direction orthogonal to a longitudinal direction of the first belt-shaped base. a pair of belt-shaped bases comprising a first belt-shaped base and a second belt-shaped base each configured to be bonded to a film of a bag body ; and an engagement portion comprising a mutually engageable first engagement portion and second engagement portion , the first and second engagement portions being provided integrally with the first and second belt-shaped bases, respectively, wherein the first belt-shaped base comprises at least two portions comprising a first portion (S1) exhibiting a first bonding strength and a second portion (S2) exhibiting a second bonding strength different from the first bonding strength when the zipper tape is bonded to the film , the first bonding strength of the first portion (SI) to the film being larger than the second bonding strength of the second portion (S2) to the film (11 A, 11B), characterized in that the at least two portions (S1, S2) are provided on a first side of the first belt-shaped base opposite a second side of the first belt-shaped base provided with the first engagement portion and between a point at which the first engagement portion is provided and an edge in a width direction orthogonal to a longitudinal direction of the first belt-shaped base.
A valve plate for a fluid pump comprising: a body having a first surface and an oppositely disposed second surface , the body defining: - a first kidney slot extending through the first and second surfaces includes a first end and an oppositely disposed second end ; - a second kidney slot extending through the first and second surfaces ; - a first notch disposed in the first surface of the body extending outwardly from the first kidney slot ; - a second notch disposed in the first surface extending outwardly from the first kidney slot , characterized in that the second notch is separated from the first notch , and both, the first notch and the second notch extend from the first end of the first kidney slot in a direction towards the second kidney slot . a body having a first surface and an oppositely disposed second surface , the body defining: - a first kidney slot extending through the first and second surfaces includes a first end and an oppositely disposed second end ; - a second kidney slot extending through the first and second surfaces ; - a first notch disposed in the first surface of the body extending outwardly from the first kidney slot ; - a second notch disposed in the first surface extending outwardly from the first kidney slot , - a first kidney slot extending through the first and second surfaces includes a first end and an oppositely disposed second end ; - a second kidney slot extending through the first and second surfaces ; - a first notch disposed in the first surface of the body extending outwardly from the first kidney slot ; - a second notch disposed in the first surface extending outwardly from the first kidney slot , characterized in that the second notch is separated from the first notch , and both, the first notch and the second notch extend from the first end of the first kidney slot in a direction towards the second kidney slot .
A compound in a therapeutically effective amount for use in treating senile dementia of the Alzheimer's Type (SDAT), wherein the compound is selected from the group consisting of: 1-alkyl, 2-acyl-glyceraldehyde-3-phosphate (G3P); 1-alkyl, 2-acyl-glycerol; 1-alkyl, 2-acyl-glycerylphosphatidylethanolamine (GPE); and pharmaceutically acceptable salts thereof, wherein the side chains are selected from a saturated or unsaturated fatty acid of the following type: 16:0 or 18:0 as alkyl at the sn-1 position, and 16:0, 18:0, 18:1, 18:2, 18:3, 20:4, 22:4, 22:6 or 24:6 as acyl at the sn-2 position. 16:0 or 18:0 as alkyl at the sn-1 position, and 16:0, 18:0, 18:1, 18:2, 18:3, 20:4, 22:4, 22:6 or 24:6 as acyl at the sn-2 position.
A modular windshield , comprising: a central component ; a first side component and a second side component ; a first support pillar disposed primarily behind the central component and the first one side component to support the central component and the first one side component , wherein little or no portion of the first support pillar is disposed between the central component and the first one side component ; and a second support pillar disposed primarily behind the central component and the second side component to support the central component and the second side component , wherein little or no portion of the second support pillar is disposed between the central component and the second side component ; wherein i) the central component is constructed of polycarbonate and wherein at least one of the first side component and the second side component is constructed of acrylic and ii) the central component comprises a thickness greater than a thickness of at least one of the first side component and the second side component . a central component ; a first side component and a second side component ; a first support pillar disposed primarily behind the central component and the first one side component to support the central component and the first one side component , wherein little or no portion of the first support pillar is disposed between the central component and the first one side component ; and a second support pillar disposed primarily behind the central component and the second side component to support the central component and the second side component , wherein little or no portion of the second support pillar is disposed between the central component and the second side component ; wherein i) the central component is constructed of polycarbonate and wherein at least one of the first side component and the second side component is constructed of acrylic and ii) the central component comprises a thickness greater than a thickness of at least one of the first side component and the second side component .
Device for coating brake discs, in particular by laser cladding, comprising: - a base with a housing forming a working space , - a workpiece carrier in the working space , wherein the workpiece carrier is configured to hold a base body of a brake disc , - a coating head configured to produce a coating on the base body , in particular by thermally induced deposition of a powder material, - a handling device that generates relative movements between the workpiece carrier and the coating head , and - a suction device for sucking off excess material from the working space , characterized in that the suction is multi-stage and comprises at least two suction stages, a first suction unit is provided for a first of the suction stages, which generates a vertically oriented flow in the working space during operation, a second suction unit is provided for a second of the suction stages, and the second suction unit comprises a collar that is associated to a circumferential section of the base body during operation, connected to a suction line and that sucks off excess material from the circumferential section during operation. - a base with a housing forming a working space , - a workpiece carrier in the working space , wherein the workpiece carrier is configured to hold a base body of a brake disc , - a coating head configured to produce a coating on the base body , in particular by thermally induced deposition of a powder material, - a handling device that generates relative movements between the workpiece carrier and the coating head , and - a suction device for sucking off excess material from the working space , the suction is multi-stage and comprises at least two suction stages, a first suction unit is provided for a first of the suction stages, which generates a vertically oriented flow in the working space during operation, a second suction unit is provided for a second of the suction stages, and the second suction unit comprises a collar that is associated to a circumferential section of the base body during operation, connected to a suction line and that sucks off excess material from the circumferential section during operation.
A waste container monitoring system comprising: a waste compactor system comprising a waste container and a hydraulic line; a monitoring assembly configured to be connected to the waste compactor system or the waste container, wherein the monitoring assembly comprises a hub device and one or more sensors connected to the hub device via one or more wired and/or wireless connections, wherein the one or more sensors are positioned on or in the waste container or the waste compactor system ; a remote processing system ; and a communication connection connecting the monitoring assembly to the remote processing system ; wherein the one or more sensors are configured to monitor one or more conditions of the container, wherein the one or more sensors comprise a pressure sensor connected to the hydraulic line and a connection sensor configured to detect the presence or absence of a connection of the waste compactor system to power or to a fixed connection; the hub device comprises a controller configured to determine fullness of the waste container based on pressure data from the pressure sensor ; and the communication connection is configured to communicate the one or more conditions to the remote processing system . a waste compactor system comprising a waste container and a hydraulic line; a monitoring assembly configured to be connected to the waste compactor system or the waste container, wherein the monitoring assembly comprises a hub device and one or more sensors connected to the hub device via one or more wired and/or wireless connections, wherein the one or more sensors are positioned on or in the waste container or the waste compactor system ; a remote processing system ; and a communication connection connecting the monitoring assembly to the remote processing system ; wherein the one or more sensors are configured to monitor one or more conditions of the container, wherein the one or more sensors comprise a pressure sensor connected to the hydraulic line and a connection sensor configured to detect the presence or absence of a connection of the waste compactor system to power or to a fixed connection; the hub device comprises a controller configured to determine fullness of the waste container based on pressure data from the pressure sensor ; and the communication connection is configured to communicate the one or more conditions to the remote processing system .
Method for controlling a machine for processing a floor surface by means of a control apparatus , comprising the following steps: - Detecting a request for local cleaning on an area of the floor surface ; - Projecting an indication of boundaries of a planned area onto the floor surface by means of a projector of the control apparatus ; - Detecting a confirmation of the area , wherein the confirmation is determined if no predetermined operating input has been detected during a predetermined time; and - Starting the processing of the area within the boundaries by means of the machine ; - characterised in that the area is determined with reference to the machine and the predetermined operating input comprises changing the position of the machine . - Detecting a request for local cleaning on an area of the floor surface ; - Projecting an indication of boundaries of a planned area onto the floor surface by means of a projector of the control apparatus ; - Detecting a confirmation of the area , wherein the confirmation is determined if no predetermined operating input has been detected during a predetermined time; and - Starting the processing of the area within the boundaries by means of the machine ; - characterised in that the area is determined with reference to the machine and the predetermined operating input comprises changing the position of the machine .
A method for producing abienol, which comprises converting geranylgeranyl diphosphate (GGPP) to abienol in the presence of a combination of class II diterpene synthase (diTPS) with at least 50% identity to a polypeptide according to SEQ ID NO:1 or SEQ ID NO:2 and bifunctional class I/II abienol synthase (CAS) with at least 50% identity to a polypeptide according to SEQ ID NO:3.
Pharmaceutical composition for use in the treatment of allergy, asthma and autoimmune diseases, wherein the pharmaceutical composition consists of one or more preparations, wherein the pharmaceutical composition comprises: a) at least one antigen or allergen, b) one or more matrices suitable for locally restricted sustained release of therapeutically effective doses of the at least one antigen or allergen, consisting of a PLGA-PEG-PLGA hydrogel, c) liposomes tailored for effective phagocytosis, by exposing on their surface phosphatidylserine, optionally containing OVA, said liposomes further containing said at least one or more antigen or allergen, d) one or more immune modulators of phagocytosis, selected from 'find me' signals namely equimolar quantities of the nucleotides ATP and UTP, embedded in the PLGA-PEG-PLGA hydrogel. wherein the pharmaceutical composition consists of one or more preparations, wherein the pharmaceutical composition comprises: a) at least one antigen or allergen, b) one or more matrices suitable for locally restricted sustained release of therapeutically effective doses of the at least one antigen or allergen, consisting of a PLGA-PEG-PLGA hydrogel, c) liposomes tailored for effective phagocytosis, by exposing on their surface phosphatidylserine, optionally containing OVA, said liposomes further containing said at least one or more antigen or allergen, d) one or more immune modulators of phagocytosis, selected from 'find me' signals namely equimolar quantities of the nucleotides ATP and UTP, embedded in the PLGA-PEG-PLGA hydrogel. a) at least one antigen or allergen, b) one or more matrices suitable for locally restricted sustained release of therapeutically effective doses of the at least one antigen or allergen, consisting of a PLGA-PEG-PLGA hydrogel, c) liposomes tailored for effective phagocytosis, by exposing on their surface phosphatidylserine, optionally containing OVA, said liposomes further containing said at least one or more antigen or allergen, d) one or more immune modulators of phagocytosis, selected from 'find me' signals namely equimolar quantities of the nucleotides ATP and UTP, embedded in the PLGA-PEG-PLGA hydrogel.
An image processing device for medical device deployment prediction, comprising: - an input unit ; - a processing unit ; and - an output unit ; wherein the input unit is configured to provide to the processing unit 3D object data of a region of interest of an object; and 3D device model data of a device for deployment inside the object using an intervention device; and live intervention image data of the region of interest comprising spatial information of an intervention device provided for the deployment of the device for deployment; wherein the processing unit is configured to localize the intervention device within the 3D object data, and then to perform a spatial registration of the live intervention image data and the 3D object data; and wherein the output unit is configured to display the expected spatial relationship, characterized in that the localization of the intervention device within the 3D object data is exclusively based on a detection of the intervention device in the live intervention image data; and wherein the processing unit is configured to adapt the 3D device model data according to the 3D object data of the region of interest using the localization of the intervention device within the 3D object data, and to embed the adapted 3D device model data, representing the device for deployment, within the 3D data of the region of interest; thus generating an expected spatial relationship between the device for deployment and the region of interest of the object. - an input unit ; - a processing unit ; and - an output unit ;
A mobile communication terminal device having a tethering function of relaying between a tethered wireless communication terminal device and a mobile communication network , comprising: a mobile communication unit configured to perform mobile communication on the mobile communication network ; a first acquisition unit configured to acquire first network information from a network information providing device regarding one or more wireless local area networks for wireless communication that is different from the mobile communication, and a second acquisition unit configured to acquire state information indicating a state of each of said one or more wireless local area networks; a network selection unit configured to select (S1060) one wireless local area network among the one or more wireless local area networks based on the state information; an information providing unit configured to provide (S1080) second network information regarding the one selected wireless network to the tethered wireless communication terminal device , wherein each of the one or more wireless networks is a wireless local area network to which the tethered terminal device is connectable through an authentication procedure, and instruct (S1080) the tethered communication terminal device to switch communication characterized in that the switch communication is from communication using tethering to communication by way of the selected wireless local area network. a mobile communication unit configured to perform mobile communication on the mobile communication network ; a first acquisition unit configured to acquire first network information from a network information providing device regarding one or more wireless local area networks for wireless communication that is different from the mobile communication, and a second acquisition unit configured to acquire state information indicating a state of each of said one or more wireless local area networks; a network selection unit configured to select (S1060) one wireless local area network among the one or more wireless local area networks based on the state information; an information providing unit configured to provide (S1080) second network information regarding the one selected wireless network to the tethered wireless communication terminal device , wherein each of the one or more wireless networks is a wireless local area network to which the tethered terminal device is connectable through an authentication procedure, and instruct (S1080) the tethered communication terminal device to switch communication provide (S1080) second network information regarding the one selected wireless network to the tethered wireless communication terminal device , wherein each of the one or more wireless networks is a wireless local area network to which the tethered terminal device is connectable through an authentication procedure, and instruct (S1080) the tethered communication terminal device to switch communication characterized in that the switch communication is from communication using tethering to communication by way of the selected wireless local area network.