mhurhangee/patent-ind-claim-en huggingface dataset:
A method for analyzing the interaction between a binding protein and a target material, comprising: (a) providing a cell comprising a construct, which comprises a polynucleotide encoding a fusion protein consisting of a binding protein and an active inclusion body protein; (b) expressing the fusion protein in the cell thereby forming interaction trapper (IT) cell, wherein the binding protein is displayed on the inclusion body; (c) introducing a fluorescence material-conjugated target material into the cell by increasing permeability of the cell according to step (b), wherein the cell maintains the activity and genetic information of the binding protein; and (d) measuring the interaction between the binding protein and the target material, which is introduced from the outside of the cell, based on the fluorescence intensity of the fluorescence material conjugated to the target material; wherein the increasing of permeability comprises making the cell membrane or the cell wall cracked, and the making comprises: (i) freezing the cell according to step (b); (ii) thawing the frozen cell; and (iii) treating the thawed cell with an acidic solution or a chelating agent. (a) providing a cell comprising a construct, which comprises a polynucleotide encoding a fusion protein consisting of a binding protein and an active inclusion body protein; (b) expressing the fusion protein in the cell thereby forming interaction trapper (IT) cell, wherein the binding protein is displayed on the inclusion body; (c) introducing a fluorescence material-conjugated target material into the cell by increasing permeability of the cell according to step (b), wherein the cell maintains the activity and genetic information of the binding protein; and (d) measuring the interaction between the binding protein and the target material, which is introduced from the outside of the cell, based on the fluorescence intensity of the fluorescence material conjugated to the target material; (i) freezing the cell according to step (b); (ii) thawing the frozen cell; and (iii) treating the thawed cell with an acidic solution or a chelating agent.
A method of forming a coated article, said method comprising: i) applying the undercoating composition comprising: a) from 20 to 40 wt.% of a vinyl chloride-vinyl acetate copolymer obtained by polymerization of a co-monomer mixture comprising, based on the total weight of the co-monomers, from 85 to 98 wt.% of vinyl chloride, from 2 to 10 wt.% of vinyl acetate and from 0 to 5 % by weight of a co-monomer selected from C 2 to C 8 olefins, vinylidene chloride and styrene; b) at least 2 wt.% of plasticizer selected from epoxidized natural oil(s); and, c) at least 2 wt.% of at least one aliphatic, cycloaliphatic or aromatic compound having a blocked isocyanate group, wherein said isocyanate group is blocked with a blocking agent capable of de-blocking at a temperature in the range of +/- 20°C compared to the de-blocking temperature of the corresponding isocyanate being blocked with nonylphenol. to at least one surface of said article; ii) applying at least one further coating composition onto said undercoating composition; and iii) curing said undercoating and said at least one further coating composition, wherein the undercoating composition is in an uncured state upon application of the coating composition immediately contacting it. i) applying the undercoating composition comprising: a) from 20 to 40 wt.% of a vinyl chloride-vinyl acetate copolymer obtained by polymerization of a co-monomer mixture comprising, based on the total weight of the co-monomers, from 85 to 98 wt.% of vinyl chloride, from 2 to 10 wt.% of vinyl acetate and from 0 to 5 % by weight of a co-monomer selected from C 2 to C 8 olefins, vinylidene chloride and styrene; b) at least 2 wt.% of plasticizer selected from epoxidized natural oil(s); and, c) at least 2 wt.% of at least one aliphatic, cycloaliphatic or aromatic compound having a blocked isocyanate group, wherein said isocyanate group is blocked with a blocking agent capable of de-blocking at a temperature in the range of +/- 20°C compared to the de-blocking temperature of the corresponding isocyanate being blocked with nonylphenol. to at least one surface of said article; a) from 20 to 40 wt.% of a vinyl chloride-vinyl acetate copolymer obtained by polymerization of a co-monomer mixture comprising, based on the total weight of the co-monomers, from 85 to 98 wt.% of vinyl chloride, from 2 to 10 wt.% of vinyl acetate and from 0 to 5 % by weight of a co-monomer selected from C 2 to C 8 olefins, vinylidene chloride and styrene; b) at least 2 wt.% of plasticizer selected from epoxidized natural oil(s); and, c) at least 2 wt.% of at least one aliphatic, cycloaliphatic or aromatic compound having a blocked isocyanate group, wherein said isocyanate group is blocked with a blocking agent capable of de-blocking at a temperature in the range of +/- 20°C compared to the de-blocking temperature of the corresponding isocyanate being blocked with nonylphenol. ii) applying at least one further coating composition onto said undercoating composition; and iii) curing said undercoating and said at least one further coating composition,
A welding device, the device comprising: - a torch holder ; - a torch body connected to the torch holder ; - an electrode connected to the torch body ; - a power source of the electrode ; the torch body comprising an upper portion connected to the torch holder , a lower portion , and a pivot link between the lower portion and the upper portion , and in that the power source comprises an electrical current lead through the upper portion , a current passage through the lower portion electrically connected to the electrode , and at least one flexible plate electrically connecting the current lead to the current passage ; characterized in that the torch body has a passage duct of the electrode , in that the welding device further comprises a protective gas source arranged to blow a protective gas into said passage duct , and in that the passage duct includes an upper duct through the upper portion of the torch body and a lower duct through the lower portion of the torch body , the upper and lower ducts both emerging in an interstice arranged between the upper and lower portions of the torch body , the power source comprising two flexible plates , positioned on either side of the interstice . - a torch holder ; - a torch body connected to the torch holder ; - an electrode connected to the torch body ; - a power source of the electrode ;
A work vehicle comprising: a positioning device for measuring the vehicle body's own position by receiving positional signals sent from a plurality of satellites ; an obstacle detection sensor for detecting an obstacle (P, E, U); and a control unit configured to have the vehicle autonomously travel by controlling steering on a planned travel path (R1) preliminarily set; wherein the control unit includes obstacle position information (D4) preliminarily stored; while traveling on the planned travel path (R1), when an obstacle (P, E, U) is detected by the obstacle detection sensor , , the control unit is configured to perform avoidance driving to avoid contact with an obstacle (P, E) and the autonomously travel is continued, when a position of the detected obstacle (P,E) is found in the obstacle position information (D4); characterized in that the control unit is configured to stop the travelling when the position of an obstacle (U) detected by the obstacle detection sensor is not found in the obstacle position information (D4). a positioning device for measuring the vehicle body's own position by receiving positional signals sent from a plurality of satellites ; an obstacle detection sensor for detecting an obstacle (P, E, U); and a control unit configured to have the vehicle autonomously travel by controlling steering on a planned travel path (R1) preliminarily set; wherein the control unit includes obstacle position information (D4) preliminarily stored; while traveling on the planned travel path (R1), when an obstacle (P, E, U) is detected by the obstacle detection sensor , , the control unit is configured to perform avoidance driving to avoid contact with an obstacle (P, E) and the autonomously travel is continued, when a position of the detected obstacle (P,E) is found in the obstacle position information (D4); characterized in that the control unit is configured to stop the travelling when the position of an obstacle (U) detected by the obstacle detection sensor is not found in the obstacle position information (D4).
Method for the state-based maintenance of a coupling arrangement of a track-bound vehicle , the coupling arrangement having at least one coupling head for coupling to a diametrically opposed coupling head of a mating coupling and optionally at least one line coupling for coupling to a line coupling of a mating coupling to transmit electrical charge and/or data and/or liquid or gaseous media, comprising: a) providing coupling arrangement data (KAD) in the form of operating data and optionally state data relating to the coupling arrangement; b) providing surroundings data (UD) for describing information relating to the ambient conditions to which the coupling arrangement is subject; c) transmitting the provided data - coupling arrangement data (KAD) and/or surroundings data (UD) - to a data processing system and determining a target specification (Xsoll) for a maintenance requirement of the coupling arrangement as a function of the provided coupling arrangement data (KAD) and surroundings data (UD); d) recording images (AB) of the coupling arrangement for optical reproduction of the actual state and transmission to the data processing system ; e) evaluating the optical actual state of the coupling arrangement from the images (AB) taking account of the target specification (Xsoll), which is formed from the operating and state data, in particular coupling arrangement data (KAD) and surroundings data (UD), for the maintenance requirement at an evaluation time and taking the evaluation as a basis for correcting (XK) the target specification (Xsoll) of the maintenance requirement. a) providing coupling arrangement data (KAD) in the form of operating data and optionally state data relating to the coupling arrangement; b) providing surroundings data (UD) for describing information relating to the ambient conditions to which the coupling arrangement is subject; c) transmitting the provided data - coupling arrangement data (KAD) and/or surroundings data (UD) - to a data processing system and determining a target specification (Xsoll) for a maintenance requirement of the coupling arrangement as a function of the provided coupling arrangement data (KAD) and surroundings data (UD); d) recording images (AB) of the coupling arrangement for optical reproduction of the actual state and transmission to the data processing system ; e) evaluating the optical actual state of the coupling arrangement from the images (AB) taking account of the target specification (Xsoll), which is formed from the operating and state data, in particular coupling arrangement data (KAD) and surroundings data (UD), for the maintenance requirement at an evaluation time and taking the evaluation as a basis for correcting (XK) the target specification (Xsoll) of the maintenance requirement.
A carrier for holding a plurality of containers (C), the carrier comprising: a plurality of panels that extends at least partially around an interior of the carrier, the panels comprising at least one bottom panel , a front panel , a back panel , and at least two side panels ; at least one central panel dividing the interior of the carrier into a front portion and a back portion; and at least one divider flap foldably attached to the at least one central panel and extending to one of the front panel and the back panel to divide one of the front portion and the back portion into at least two container-receiving spaces , the at least one divider flap having a main panel foldably connected to the at least one central panel and at least one beveled portion foldably connected to the main panel and oblique to the main panel. a plurality of panels that extends at least partially around an interior of the carrier, the panels comprising at least one bottom panel , a front panel , a back panel , and at least two side panels ; at least one central panel dividing the interior of the carrier into a front portion and a back portion; and at least one divider flap foldably attached to the at least one central panel and extending to one of the front panel and the back panel to divide one of the front portion and the back portion into at least two container-receiving spaces , the at least one divider flap having a main panel foldably connected to the at least one central panel and at least one beveled portion foldably connected to the main panel and oblique to the main panel.
Guided light source , comprising: - at least one quantum box associated with a discoid wave guide to achieve cylindrical propagation of a wave front emitted by the at least one quantum box in the discoid wave guide; - an annular wave guide surrounding said discoid wave guide and having a grating coupler (T) formed on its internal periphery to receive said wave front in normal incidence; - an output wave guide optically coupled to the annular wave guide. - at least one quantum box associated with a discoid wave guide to achieve cylindrical propagation of a wave front emitted by the at least one quantum box in the discoid wave guide; - an annular wave guide surrounding said discoid wave guide and having a grating coupler (T) formed on its internal periphery to receive said wave front in normal incidence; - an output wave guide optically coupled to the annular wave guide.
A CD24 protein for use in treating immune-related adverse events (irAEs) associated with a cancer therapy in a subject.
Method for producing a bead wire intended for the reinforcement of a tyre, such as a pneumatic tyre, said method comprising a braiding step (S1) during which a braid wire is wound in helical turns about, and along, a generatrix line (L3) which is closed in a ring on itself about an axis called "main axis" (Z3), and several successive complete turns in azimuth about the main axis are thus described with said braid wire , so as to form, about said main axis (Z3), a bead wire element called "braided torus" within which the braid wire has, on the one hand, a portion of length called "winding section" which corresponds to the helical turns and which occupies a volume called "braid volume" (V5), and, on the other hand, in an extension of said winding section , a surplus length of braid wire called "excess section" (6, 6_in, 6_out), said method comprising, after the braiding step (S1), a folding step (S2) during which the excess section (6, 6_in, 6_out) is deformed plastically by folding, so as to form an elbow (17, 17_in, 17_out) which makes the excess section (6, 6_in, 6_out) diverge with respect to the helical turns and makes said excess section (6, 6_in, 6_out) protrude at least partly with respect to the braid volume (V5) of the braided torus .
A floor beam of steel with a section showing at least two in principal vertically oriented webs , one to the webs upper part fixed horizontal top flange , one to the webs lower parts fixed horizontal bottom flange extended outside the webs, acting as support for a floor preferably of concrete elements, wherein one extra horizontal flange is fixed between the webs at a distance above the bottom flange at the same time as a space between the bottom flange and the flange contains a fire protective heat insulating material , characterized by that the fire protective heat insulating material is fixed inside the beam already when producing the same.
A method of fabricating a holographic security label comprising steps of: dot-matrix laser patterning of a hologram in defined design areas and of alignment marks in a photoresist layer on a glass substrate; development of the exposed photoresist areas with the alignment marks on a far side of the photoresist layer on the glass substrate forming a specimen; vacuum deposition of an auxiliary aluminium film with a thickness of 100-200 nm; spin coating of a single layer of PMMA ; precise alignment and angle correction between dot-matrix and electron beam patterning areas by scanning electron microscope; electron beam patterning; development of PMMA ; Ce(NH 4 ) 2 (NO 3 ) 6 :HNO 3 etching of the aluminium film ; photoresist exposure ( λ = 405 nm); lift-off of the PMMA and of the etched aluminium layer ; final development of the photoresist fabricating aligned areas of dot-matrix and electron beam patterned hologram ; vacuum deposition of a silver film ; electrochemical deposition of a nickel film ; producing of a nickel shim for roll-to-roll replication; replication of the holograms in a multilayer metallized or transparent polymer film ; coating the film with pressure-sensitive, thermoplastic or thermosetting adhesive and dividing into individual labels. dot-matrix laser patterning of a hologram in defined design areas and of alignment marks in a photoresist layer on a glass substrate; development of the exposed photoresist areas with the alignment marks on a far side of the photoresist layer on the glass substrate forming a specimen; vacuum deposition of an auxiliary aluminium film with a thickness of 100-200 nm; spin coating of a single layer of PMMA ; precise alignment and angle correction between dot-matrix and electron beam patterning areas by scanning electron microscope; electron beam patterning; development of PMMA ; Ce(NH 4 ) 2 (NO 3 ) 6 :HNO 3 etching of the aluminium film ; photoresist exposure ( λ = 405 nm); lift-off of the PMMA and of the etched aluminium layer ; final development of the photoresist fabricating aligned areas of dot-matrix and electron beam patterned hologram ; vacuum deposition of a silver film ; electrochemical deposition of a nickel film ; producing of a nickel shim for roll-to-roll replication; replication of the holograms in a multilayer metallized or transparent polymer film ; coating the film with pressure-sensitive, thermoplastic or thermosetting adhesive and dividing into individual labels.
A tissue capture anchor for attaching tissue to bone, the anchor comprising: an expandable anchor body ; and a spreader configured for displacement along an axis of the anchor body between a first position and a second position, the spreader comprising: a proximal end with a means for receiving an insertion tool; a central body and a distal end ; and an angled portion configured to expand the anchor body as the spreader is advanced from the first position to the second position, wherein the spreader further comprises a generally flat-shaped face at the distal end ; wherein the distal end comprises two openings for receiving limbs of a suture loop characterized in that the spreader includes a plurality of spikes that can engage with tissue. an expandable anchor body ; and a spreader configured for displacement along an axis of the anchor body between a first position and a second position, the spreader comprising: a proximal end with a means for receiving an insertion tool; a central body and a distal end ; and an angled portion configured to expand the anchor body as the spreader is advanced from the first position to the second position, wherein the spreader further comprises a generally flat-shaped face at the distal end ; wherein the distal end comprises two openings for receiving limbs of a suture loop characterized in that the spreader includes a plurality of spikes that can engage with tissue. a proximal end with a means for receiving an insertion tool; a central body and a distal end ; and an angled portion configured to expand the anchor body as the spreader is advanced from the first position to the second position, wherein the spreader further comprises a generally flat-shaped face at the distal end ; wherein the distal end comprises two openings for receiving limbs of a suture loop characterized in that the spreader includes a plurality of spikes that can engage with tissue.
Measuring device having a transmitter for transmitting a measurement signal, a receiver for receiving a response to the transmitted measurement signal and a signal processing device (7, 8, 9; 18) for determining a measurement result from the response, the transmitter and/or the receiver having a coil (3; 4; 16), characterized in that the measuring device comprises a calibration device for reducing an interference influence on the measurement result, wherein the calibration device is configured such that a current pulse can be introduced into the coil (3; 4; 16) of the receiver from a current source (DC) and the signal processing device (7, 8, 9; 18) can perform a measurement value correction using a calibration signal generated by the current pulse for determining the measurement result from the response and can determine a measurement result from the response and the measurement value correction, and/or a current pulse can be introduced into the coil (3; 16) of the transmitter from a current source (DC) and a signal processing device (7, 8, 9; 18) connected to the coil (3; 16) of the receiver can perform the measurement value correction using a calibration signal generated by the current pulse and determine the measurement result from the response and the measurement value correction. a current pulse can be introduced into the coil (3; 4; 16) of the receiver from a current source (DC) and the signal processing device (7, 8, 9; 18) can perform a measurement value correction using a calibration signal generated by the current pulse for determining the measurement result from the response and can determine a measurement result from the response and the measurement value correction, and/or a current pulse can be introduced into the coil (3; 16) of the transmitter from a current source (DC) and a signal processing device (7, 8, 9; 18) connected to the coil (3; 16) of the receiver can perform the measurement value correction using a calibration signal generated by the current pulse and determine the measurement result from the response and the measurement value correction.
A device for orbital processing of ends and non-rotating butt joints of a pipe configured for installation and movement around an outer surface of the pipe and comprising a clamping device and a flexible composite carriage consisting of at least two components (2, 3; 4; 23) joined together via a pivotal connection and configured to pivot only around a pivot pin of the pivotal connection lying parallel to an axis of the pipe, wherein each component of the flexible composite carriage comprises a group of at least two coaxial supporting rollers , an axis of which is situated at a distance from the pivotal connection that is less than or equal to 1/3 of a distance between the pivotal connections of the components and is parallel to the axis of the pipe, and wherein the components of the flexible composite carriage are connected to each other in series in such a way that each component bears on two groups of supporting rollers , - one of which is mounted on the component itself, and the other is mounted on an adjacent component, and one of two end components of the carriage bears on an additional group of supporting rollers installed on the said component or on the clamping device as an open chain of individual links , and wherein at least one component (2; 4) of the flexible composite carriage is equipped with a supporting-driven roller and a drive mechanism with a torque source configured to move the flexible composite carriage along the pipe surface around its axis by means of driven rollers, and wherein at least one component of the flexible composite carriage has at least one functional unit for pipe processing.