An air cleaner assembly comprising: (a) a housing including: a housing body ; and, an access cover ; (i) the housing body having: an open service access end ; and, a main filter cartridge sealing shelf recessed from the open service access end ; (ii) the access cover comprising a precleaner assembly including a flow separator tube arrangement comprising a plurality of flow separator tubes ; (A) the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body ; and, (iii) the housing including: an air flow inlet arrangement; an air flow outlet arrangement ; and, a contaminant evacuation port arrangement ; and, (b) a main filter cartridge removably positioned within the housing body ; the main filter cartridge comprising; (i) a media pack having an inlet end and an opposite outlet end ; and, (ii) a housing seal arrangement comprising a perimeter pinch seal removably positioned sealingly biased against the main cartridge sealing shelf . (a) a housing including: a housing body ; and, an access cover ; (i) the housing body having: an open service access end ; and, a main filter cartridge sealing shelf recessed from the open service access end ; (ii) the access cover comprising a precleaner assembly including a flow separator tube arrangement comprising a plurality of flow separator tubes ; (A) the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body ; and, (iii) the housing including: an air flow inlet arrangement; an air flow outlet arrangement ; and, a contaminant evacuation port arrangement ; and, (i) the housing body having: an open service access end ; and, a main filter cartridge sealing shelf recessed from the open service access end ; (ii) the access cover comprising a precleaner assembly including a flow separator tube arrangement comprising a plurality of flow separator tubes ; (A) the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body ; and, (A) the access cover being removably mounted on the housing body over the service access end and with the flow separator tube arrangement projecting into the housing body to a location surrounded by the housing body ; and, (iii) the housing including: an air flow inlet arrangement; an air flow outlet arrangement ; and, a contaminant evacuation port arrangement ; and, (b) a main filter cartridge removably positioned within the housing body ; the main filter cartridge comprising; (i) a media pack having an inlet end and an opposite outlet end ; and, (ii) a housing seal arrangement comprising a perimeter pinch seal removably positioned sealingly biased against the main cartridge sealing shelf . (i) a media pack having an inlet end and an opposite outlet end ; and, (ii) a housing seal arrangement comprising a perimeter pinch seal removably positioned sealingly biased against the main cartridge sealing shelf . <EOS>