A biomarker monitoring system comprising: a communications network; a portable wellness device configured to form a communication link with the communications network, the portable wellness device including a detector configured to detect at least one biomarker in a biologic sample, wherein the at least one biomarker comprises: at least one first biomarker associated with a T helper 1 cell; at least one second biomarker associated with a T helper 2 cell; and at least one third biomarker associated with a T regulatory cell, a detector configured to detect at least one personal factor selected from the group consisting of temperature, heart rate, or respiration rate, a first memory, a plurality of program instructions stored in the first memory, and a processing circuit operably connected to the first memory and configured to execute the program instructions to generate wellness data over a period of time based upon detection of the at least one biomarker in the biologic sample; and a remote user interface operably connected to the communications network and configured to render the wellness data, wherein the rendered wellness data depicts a variation associated with the at least one biomarker and the at least one personal factor during the period of time along with one or more of a depiction of a variation of the at least one personal factor during the period of time and depiction of a variation of an environmental factor during the period of time. a communications network; a portable wellness device configured to form a communication link with the communications network, the portable wellness device including a detector configured to detect at least one biomarker in a biologic sample, wherein the at least one biomarker comprises: at least one first biomarker associated with a T helper 1 cell; at least one second biomarker associated with a T helper 2 cell; and at least one third biomarker associated with a T regulatory cell, a detector configured to detect at least one personal factor selected from the group consisting of temperature, heart rate, or respiration rate, a first memory, a plurality of program instructions stored in the first memory, and a processing circuit operably connected to the first memory and configured to execute the program instructions to generate wellness data over a period of time based upon detection of the at least one biomarker in the biologic sample; and a detector configured to detect at least one biomarker in a biologic sample, wherein the at least one biomarker comprises: at least one first biomarker associated with a T helper 1 cell; at least one second biomarker associated with a T helper 2 cell; and at least one third biomarker associated with a T regulatory cell, at least one first biomarker associated with a T helper 1 cell; at least one second biomarker associated with a T helper 2 cell; and at least one third biomarker associated with a T regulatory cell, a detector configured to detect at least one personal factor selected from the group consisting of temperature, heart rate, or respiration rate, a first memory, a plurality of program instructions stored in the first memory, and a processing circuit operably connected to the first memory and configured to execute the program instructions to generate wellness data over a period of time based upon detection of the at least one biomarker in the biologic sample; and a remote user interface operably connected to the communications network and configured to render the wellness data, <EOS>