mhurhangee/patent-ind-claim-en huggingface dataset:
An inhaler for oral delivery of medication , the inhaler comprising: an actuation detector configured to provide an actuation signal in response to release of the medication from the inhaler ; an accelerometer configured to measure an orientation of the inhaler, and a processor coupled to the actuation detector and the accelerometer , characterized in that the processor is configured with processor-executable instructions to: determine an activation duration based on a total period in which the medication is released, wherein the total period is identified based on the actuation signal; determine an improper usage duration, wherein the improper usage duration is a period during the activation duration in which the orientation of the inhaler deviates from a preferred orientation by an amount that exceeds a predetermined proper orientation threshold; and determine a quality of use of the inhaler based on a difference between the actuation duration and the improper usage duration. an actuation detector configured to provide an actuation signal in response to release of the medication from the inhaler ; an accelerometer configured to measure an orientation of the inhaler, and a processor coupled to the actuation detector and the accelerometer , characterized in that the processor is configured with processor-executable instructions to: determine an activation duration based on a total period in which the medication is released, wherein the total period is identified based on the actuation signal; determine an improper usage duration, wherein the improper usage duration is a period during the activation duration in which the orientation of the inhaler deviates from a preferred orientation by an amount that exceeds a predetermined proper orientation threshold; and determine a quality of use of the inhaler based on a difference between the actuation duration and the improper usage duration. determine an activation duration based on a total period in which the medication is released, wherein the total period is identified based on the actuation signal; determine an improper usage duration, wherein the improper usage duration is a period during the activation duration in which the orientation of the inhaler deviates from a preferred orientation by an amount that exceeds a predetermined proper orientation threshold; and determine a quality of use of the inhaler based on a difference between the actuation duration and the improper usage duration.
InP/ZnSe/ZnS core-shell nanostructures, wherein the thickness of at least one of the ZnSe and ZnS shells is between 0.7nm and 3.5nm, wherein the nanostructures exhibit a photoluminescence quantum yield of 60-99%, wherein the photoluminescence spectrum of the population of core-shell nanostructures exhibits a full width half maximum of 35nm to 45nm; and wherein the nanostructures exhibit an OD 450 /peak ratio of about 1.0 to about 2.0, wherein the OD 450 /peak ratio is defined as the optical density of a sample of the nanostructures measured at 450 nm divided by the optical density at the first exciton peak absorption wavelength of the sample of nanostructures.
A compound for use in a method for treating hepatic ischemia/reperfusion injury, wherein said compound is a thiosulfate.
A method for detecting a target object, comprising: generating a signal by energizing a shaped coil with an AC signal; receiving at a sensor a signal reflected by a target in response to the signal from the shaped coil , characterized in that : the shaped coil has a varying width; the sensor includes a first sensing element aligned with the shaped coil at a first width and a second sensing element aligned with shaped coil at a second width; and the method further comprises selecting a first one of the first and second sensing elements based upon a ratio of coil width and a distance from the target to the shaped coil . generating a signal by energizing a shaped coil with an AC signal; receiving at a sensor a signal reflected by a target in response to the signal from the shaped coil , the shaped coil has a varying width; the sensor includes a first sensing element aligned with the shaped coil at a first width and a second sensing element aligned with shaped coil at a second width; and the method further comprises selecting a first one of the first and second sensing elements based upon a ratio of coil width and a distance from the target to the shaped coil .
Braking system for at least one railway vehicle (RV), wherein said braking system is arranged to provide to at least one trackside signaling system (TS), or to at least one on-board vehicle signaling system (OB), or to both at least one trackside signaling system (TS) and at least one on-board vehicle signaling system (OB), information regarding respective factors affecting braking of the railway vehicle; wherein said information regarding respective factors affecting the braking of the railway vehicle includes: - information regarding a correction factor to be applied to a predefined nominal deceleration value of the at least one railway vehicle in conditions of low adhesion, k wet ; wherein said information regarding factors affecting the braking of the railway vehicle is determined in real time by said braking system. wherein said information regarding respective factors affecting the braking of the railway vehicle includes: - information regarding a correction factor to be applied to a predefined nominal deceleration value of the at least one railway vehicle in conditions of low adhesion, k wet ; - information regarding a correction factor to be applied to a predefined nominal deceleration value of the at least one railway vehicle in conditions of low adhesion, k wet ; wherein said information regarding factors affecting the braking of the railway vehicle is determined in real time by said braking system.
A splash resistant multi-layered structure , the multi-layered structure comprising: an outer layer of material having an outer-facing surface and an inner-facing surface ; an inner layer of material having an outer-facing surface and an inner-facing surface ; and a first plurality of three-dimensional spacers disposed on a surface within the multi-layered structure , wherein the first plurality of three-dimensional spacers define a space between the outer layer of material and the inner layer of material , wherein the space spans a distance at least as great as a maximum height of the first plurality of three-dimensional spacers , further wherein the first plurality of three-dimensional spacers aid in absorbing energy associated with a fluid contacting the outer layer of material ; characterised in that : the first plurality of three-dimensional spacers comprise a binder, an ink, an adhesive, or a combination thereof, and an encapsulated functional additive contained within the binder, the ink, the adhesive, or the combination thereof, wherein the encapsulated functional additive comprises a phase change material. an outer layer of material having an outer-facing surface and an inner-facing surface ; an inner layer of material having an outer-facing surface and an inner-facing surface ; and a first plurality of three-dimensional spacers disposed on a surface within the multi-layered structure , wherein the first plurality of three-dimensional spacers define a space between the outer layer of material and the inner layer of material , wherein the space spans a distance at least as great as a maximum height of the first plurality of three-dimensional spacers , further wherein the first plurality of three-dimensional spacers aid in absorbing energy associated with a fluid contacting the outer layer of material ;
A preparation method of trisodium AHU-377 and Valsartan co-crystal hydrate Form II, wherein the X-ray powder diffraction pattern (CuKa radiation) of said Form II has characteristic peaks at 2theta values of 4.3°±0.2°, 5.0°±0.2° and 12.8°±0.2°, said preparation method comprises the following steps: Step 1: preparing a clear solution containing trisodium AHU-377 and Valsartan, wherein said clear solution comprises a first solvent and a second solvent; the first solvent is an anti-solvent of Form II, and can form azeotrope with water, the second solvent is a good solvent of Form II, and the boiling point of the second solvent is lower than that of the first solvent; Step 2: evaporating the clear solution obtained in Step 1 under vacuum or under nitrogen purging to remove the second solvent and water from the system; and Step 3: mixing the system obtained in Step 2 with water, a third solvent and with or without seed crystals of Form II, then stirring for crystallization, filtering, washing and drying to obtain Form II, wherein said third solvent is an anti-solvent of Form II, which is miscible in the first solvent, and water is soluble in said third solvent; wherein the first solvent is one or more solvents selected from methylbenzene, xylene, cyclohexane, isopropyl acetate and methyl isobutyl ketone, and/or the second solvent is methanol or ethanol or a combination thereof, and/or the third solvent is one or more solvents selected from ethyl acetate, acetone, 2-butanone, isopropyl acetate and methyl isobutyl ketone. Step 1: preparing a clear solution containing trisodium AHU-377 and Valsartan, wherein said clear solution comprises a first solvent and a second solvent; the first solvent is an anti-solvent of Form II, and can form azeotrope with water, the second solvent is a good solvent of Form II, and the boiling point of the second solvent is lower than that of the first solvent; Step 2: evaporating the clear solution obtained in Step 1 under vacuum or under nitrogen purging to remove the second solvent and water from the system; and Step 3: mixing the system obtained in Step 2 with water, a third solvent and with or without seed crystals of Form II, then stirring for crystallization, filtering, washing and drying to obtain Form II, wherein said third solvent is an anti-solvent of Form II, which is miscible in the first solvent, and water is soluble in said third solvent; wherein
Method for operating a cleaning system with a plurality of mobile cleaning devices and a base station for the cleaning devices , wherein the cleaning devices are emptied and/or filled with a cleaning agent by the base station according to a prioritization, wherein emptying and/or filling of a first cleaning device is interrupted when a second cleaning device is connected to the base station .
A disc brake comprising: an actuation mechanism comprising a piston for applying an actuating force to a brake pad, and a wear adjustment mechanism for adjusting extension of the piston to account for wear of said brake pad, the wear adjustment mechanism comprising a manual rewind apparatus having a manual adjuster shaft ; a brake caliper having a housing cavity for at least partly accommodating the actuation mechanism , the housing cavity being partially defined by an inboard wall of the brake caliper ; characterised by an inboard support interface and an outboard support interface where the manual adjuster shaft is supported; wherein the inboard support interface is located within the housing cavity , outboard of the inboard wall . an actuation mechanism comprising a piston for applying an actuating force to a brake pad, and a wear adjustment mechanism for adjusting extension of the piston to account for wear of said brake pad, the wear adjustment mechanism comprising a manual rewind apparatus having a manual adjuster shaft ; a brake caliper having a housing cavity for at least partly accommodating the actuation mechanism , the housing cavity being partially defined by an inboard wall of the brake caliper ; characterised by an inboard support interface and an outboard support interface where the manual adjuster shaft is supported; wherein the inboard support interface is located within the housing cavity , outboard of the inboard wall .
Actuator for producing a thrust force over a particular travel, comprising a nut , a screw , a bush configured to surround the screw in an axial direction (X-X) of the screw , a plurality of rollers , the nut being configured to cooperate with the screw , the nut being fastened to the rollers , free to rotate, each roller being configured to move in particular in one of at least one helical guide of the bush , the screw being configured so that when it is turned it causes the actuator to function to drive the nut in rotation when it bears via the rollers on a profile of the helical guide and therefore to advance in the axial direction (X-X) of the screw more or less quickly depending on the slope of the profile of the helical guide , the actuator further comprising a motor (M) configured to turn the screw , characterized in that successive values of the slope all along the profile or profiles of one or more respective helical guides are such that the slope systematically compensates at least one peak of the desired thrust force in order to clip maximum values of the thrust force so that the motor, the screw and the nut are sized for a motor torque value corresponding to the value of the thrust force after clipping. a nut , a screw , a bush configured to surround the screw in an axial direction (X-X) of the screw , a plurality of rollers , the nut being configured to cooperate with the screw , the nut being fastened to the rollers , free to rotate, each roller being configured to move in particular in one of at least one helical guide of the bush , the screw being configured so that when it is turned it causes the actuator to function to drive the nut in rotation when it bears via the rollers on a profile of the helical guide and therefore to advance in the axial direction (X-X) of the screw more or less quickly depending on the slope of the profile of the helical guide , the actuator further comprising a motor (M) configured to turn the screw , characterized in that successive values of the slope all along the profile or profiles of one or more respective helical guides are such that the slope systematically compensates at least one peak of the desired thrust force in order to clip maximum values of the thrust force so that the motor, the screw and the nut are sized for a motor torque value corresponding to the value of the thrust force after clipping.
The triple combination of active ingredients with the INN's vemurafenib, cobimetinib and atezolizumab for use in treating cancer in an individual, characterized by first administering to the individual an effective amount of vemurafenib and cobimetinib and second administering to the individual an effective amount of vemurafenib, cobimetinib and atezolizumab.
A packing device system for filling fuel elements , comprising: a fuel element including an outer shell defining a fill aperture the packing device system further comprising: a stationary base configured to be received on a support surface; a clamp assembly including a body defining a bore therein, the bore being configured to slidably receive the fuel element therein, and an adjustment member configured to exert force on a corresponding fuel element disposed within the bore of the body, wherein the clamp assembly is movable along a vertical axis with respect to the stationary base; characterised by a cam assembly including a cam and a drive motor configured to rotate the cam, wherein the cam assembly is mounted on the stationary base beneath the clamp assembly so that rotation of the cam alternatingly raises the clamp assembly up along the vertical axis and subsequently drops the clamp assembly; and a powder reservoir assembly including a powder reservoir , a fill needle in fluid communication with the powder reservoir, and a reservoir support that is adjustably secured to the body of the clamp assembly so that the powder reservoir can be adjusted vertically. a stationary base configured to be received on a support surface; a clamp assembly including a body defining a bore therein, the bore being configured to slidably receive the fuel element therein, and an adjustment member configured to exert force on a corresponding fuel element disposed within the bore of the body, wherein the clamp assembly is movable along a vertical axis with respect to the stationary base; characterised by a cam assembly including a cam and a drive motor configured to rotate the cam, wherein the cam assembly is mounted on the stationary base beneath the clamp assembly so that rotation of the cam alternatingly raises the clamp assembly up along the vertical axis and subsequently drops the clamp assembly; and a powder reservoir assembly including a powder reservoir , a fill needle in fluid communication with the powder reservoir, and a reservoir support that is adjustably secured to the body of the clamp assembly so that the powder reservoir can be adjusted vertically.
A data packet forwarding method, applied to a virtual network in which control and forwarding are separated, wherein the virtual network comprises a controller and a forwarding device, and the method comprises: receiving (21-01), by the forwarding device, a first default flow entry of the virtual network from the controller; receiving, by the forwarding device, a second default flow entry of the virtual network from the controller; receiving (21-02), by the forwarding device, a first data packet from an end system, ES, in the virtual network; the method being characterised in that when the controller is faulty and the forwarding device looks up a first flow table based on a match item of the first data packet but no flow entry is hit, sending (21-03), by the forwarding device, the first data packet to a specified forwarding device by using the first default flow entry of the virtual network; when the controller works normally and the forwarding device looks up the first flow table based on the match item of the first data packet but no flow entry is hit, sending, by the forwarding device, the first data packet to the controller by using the second default flow entry of the virtual network. receiving (21-01), by the forwarding device, a first default flow entry of the virtual network from the controller; receiving, by the forwarding device, a second default flow entry of the virtual network from the controller; receiving (21-02), by the forwarding device, a first data packet from an end system, ES, in the virtual network; the method being characterised in that when the controller is faulty and the forwarding device looks up a first flow table based on a match item of the first data packet but no flow entry is hit, sending (21-03), by the forwarding device, the first data packet to a specified forwarding device by using the first default flow entry of the virtual network; when the controller works normally and the forwarding device looks up the first flow table based on the match item of the first data packet but no flow entry is hit, sending, by the forwarding device, the first data packet to the controller by using the second default flow entry of the virtual network.
An airfoil for a gas turbine engine , the airfoil comprising: an airfoil wall defining a leading end , a trailing end , and first and second sides joining the leading end and the trailing end , the first and second sides spanning in a radial direction; and first, second, and third ribs connecting the first and second sides of the airfoil wall , each of the first, second, and third ribs defining a tube portion circumscribing a rib passage , and first and second connector arms solely joining the tube portion to, respectively, the first and second sides of the airfoil wall ; the first rib and the airfoil wall bounding a first cooling channel there between that is flow isolated from the rib passage of the first rib ; characterized in that the first rib , the second rib , and the airfoil wall bounding a second cooling channel there between that is flow isolated from the first cooling channel , the first rib having a first cooling aperture fluidly connecting the rib passage and the second cooling channel ; and the second rib , the third rib , and the airfoil wall bounding a third cooling channel there between that is flow isolated from each of the first cooling channel and second cooling channel , the second rib having a second cooling aperture fluidly connecting the rib passage of the second rib and the third cooling channel . an airfoil wall defining a leading end , a trailing end , and first and second sides joining the leading end and the trailing end , the first and second sides spanning in a radial direction; and first, second, and third ribs connecting the first and second sides of the airfoil wall , each of the first, second, and third ribs defining a tube portion circumscribing a rib passage , and first and second connector arms solely joining the tube portion to, respectively, the first and second sides of the airfoil wall ; a tube portion circumscribing a rib passage , and first and second connector arms solely joining the tube portion to, respectively, the first and second sides of the airfoil wall ; the first rib and the airfoil wall bounding a first cooling channel there between that is flow isolated from the rib passage of the first rib ; characterized in that the first rib , the second rib , and the airfoil wall bounding a second cooling channel there between that is flow isolated from the first cooling channel , the first rib having a first cooling aperture fluidly connecting the rib passage and the second cooling channel ; and the second rib , the third rib , and the airfoil wall bounding a third cooling channel there between that is flow isolated from each of the first cooling channel and second cooling channel , the second rib having a second cooling aperture fluidly connecting the rib passage of the second rib and the third cooling channel .
A method performed by an electronic device, comprising: generating a plurality of bounding regions based on an image; determining a subset of the plurality of bounding regions based on a color difference criterion and a selected area in the image, wherein the color difference criterion distinguishes between bounding regions based on a color distance between a bounding region and a respective surrounding region, whereby any of the plurality of bounding regions that do not meet the color difference criterion are rejected; and processing the image based on the subset of the plurality of bounding regions. generating a plurality of bounding regions based on an image; determining a subset of the plurality of bounding regions based on a color difference criterion and a selected area in the image, wherein the color difference criterion distinguishes between bounding regions based on a color distance between a bounding region and a respective surrounding region, whereby any of the plurality of bounding regions that do not meet the color difference criterion are rejected; and processing the image based on the subset of the plurality of bounding regions.