mhurhangee/patent-ind-claim-en huggingface dataset:
A method for nucleic acid sequencing comprising: providing a substrate comprising an array of nanoFETs, each comprising a source, a drain, and a gate, wherein a plurality of the nanoFETs comprise a single polymerase enzyme complex comprising a polymerase enzyme and a template nucleic acid, the complex attached to the gate of the nanoFET, wherein the polymerase enzyme is attached to the gate in an orientation whereby the nucleotide exit region of the polymerase enzyme is toward the gate of the nanoFET; exposing the substrate to a plurality of types of nucleotide analogs, each comprising a different conductivity label attached to the phosphate portion of the nucleotide analog through a linker under conditions whereby polymerase mediated nucleic acid synthesis occurs, resulting in cleavage of the conductivity label and the growth of a nascent nucleic acid strand; applying a voltage between the source and drain, whereby when a nucleotide analog resides in the active site of the enzyme, the conductivity label on the nucleotide analog produces a measurable change in the electrical signal at the gate; monitoring an electrical signal at the gate over time, whereby the electrical signal indicates an incorporation event for a type of nucleotide analog having a specific conductivity label; and using the electrical signal to determine a sequence of the template nucleic acid. providing a substrate comprising an array of nanoFETs, each comprising a source, a drain, and a gate, wherein a plurality of the nanoFETs comprise a single polymerase enzyme complex comprising a polymerase enzyme and a template nucleic acid, the complex attached to the gate of the nanoFET, wherein the polymerase enzyme is attached to the gate in an orientation whereby the nucleotide exit region of the polymerase enzyme is toward the gate of the nanoFET; exposing the substrate to a plurality of types of nucleotide analogs, each comprising a different conductivity label attached to the phosphate portion of the nucleotide analog through a linker under conditions whereby polymerase mediated nucleic acid synthesis occurs, resulting in cleavage of the conductivity label and the growth of a nascent nucleic acid strand; applying a voltage between the source and drain, whereby when a nucleotide analog resides in the active site of the enzyme, the conductivity label on the nucleotide analog produces a measurable change in the electrical signal at the gate; monitoring an electrical signal at the gate over time, whereby the electrical signal indicates an incorporation event for a type of nucleotide analog having a specific conductivity label; and using the electrical signal to determine a sequence of the template nucleic acid.
A chair for a cable transportation system; the chair comprising: - a row of seats placed side by side; - a protection device movable with respect to the seats between a first distal position wherein it does not hinder the embarkation and disembarkation of passengers and a second position proximal to the seats wherein it performs the function of protecting passengers during transportation; and - a plurality of cord devices coupled to the protection device ; each cord device being configured to be grasped and moved manually by the passengers seated on the seats for moving the protection device by pulling from the first position to the second position; characterized in that each cord device is configured in such a way that for a first movement section it has an elastic behaviour generating an elongation without pulling the protection device and for a second movement section, subsequent to the first one, it has a rigid behaviour generating the pulling of the protection device ; wherein the cord device comprises: - a cord made of a material configured to elongate elastically due to manual pulling by the passengers until reaching a maximum elongation which is at least equal to about 10% of the length at rest; or a spring device connected to the protection device and a cord made of non-extendible material; the spring device being configured to elongate elastically due to manual pulling by the passengers until a maximum elongation is reached. - a row of seats placed side by side; - a protection device movable with respect to the seats between a first distal position wherein it does not hinder the embarkation and disembarkation of passengers and a second position proximal to the seats wherein it performs the function of protecting passengers during transportation; and - a plurality of cord devices coupled to the protection device ; each cord device being configured to be grasped and moved manually by the passengers seated on the seats for moving the protection device by pulling from the first position to the second position; each cord device is configured in such a way that for a first movement section it has an elastic behaviour generating an elongation without pulling the protection device and for a second movement section, subsequent to the first one, it has a rigid behaviour generating the pulling of the protection device ; wherein the cord device comprises: - a cord made of a material configured to elongate elastically due to manual pulling by the passengers until reaching a maximum elongation which is at least equal to about 10% of the length at rest; or - a cord made of a material configured to elongate elastically due to manual pulling by the passengers until reaching a maximum elongation which is at least equal to about 10% of the length at rest; or a spring device connected to the protection device and a cord made of non-extendible material; the spring device being configured to elongate elastically due to manual pulling by the passengers until a maximum elongation is reached.
Dust bag removal module for manual arrangement in a vacuum cleaner and for manual removal from the vacuum cleaner , the dust bag removal module having a first coupling interface which is repeatedly separable and connectable for separating from and connecting to the vacuum cleaner , and a second coupling interface which is repeatedly separable and connectable for separating from and connecting to a dust bag , the dust bag removal module having a grip surface for manually gripping the dust bag removal module when the first coupling interface is removed and separated from the vacuum cleaner , and when the first coupling interface is arranged and connected to the vacuum cleaner , and the dust bag removal module having a decoupling device for manually separating the connection to the dust bag at the second coupling interface , the dust bag removal module having an air guide for guiding an air flow from a coupled vacuum cleaner into a coupled dust bag , characterised in that at least one flap is arranged in the air guide , the at least one flap being configured to be moved by a differential pressure applied to the flap into an open position for the air flow of the coupled vacuum cleaner through the air guide .
A method of managing routing and replication of data at a first node of a network comprising a plurality of nodes, the method comprising: wirelessly establishing communication with one or more other nodes of the plurality of nodes; gathering operating parameters of the first node and of the one or more other nodes via one or more wireless communication links, the gathering producing a collection of context information at the first node; determining whether a data bundle is available for processing by the first node; and if a data bundle is available for processing by the first node, choosing to perform one of the following actions with the data bundle, based on the context information and a set of rules for the first node for a direction of communication of the data bundle: transmitting the data bundle from the first node towards a second node of the plurality of nodes via a number of communication links, storing the data bundle at the first node, and dropping the data bundle from memory of the first node; wherein transmitting the data bundle from the first node towards the second node of the plurality of nodes via the number of communication links comprises determining that the number of communication links is two or more, based on the context information indicative of quality of communication of the first node with neighbor nodes of the plurality of nodes. wirelessly establishing communication with one or more other nodes of the plurality of nodes; gathering operating parameters of the first node and of the one or more other nodes via one or more wireless communication links, the gathering producing a collection of context information at the first node; determining whether a data bundle is available for processing by the first node; and if a data bundle is available for processing by the first node, choosing to perform one of the following actions with the data bundle, based on the context information and a set of rules for the first node for a direction of communication of the data bundle: transmitting the data bundle from the first node towards a second node of the plurality of nodes via a number of communication links, storing the data bundle at the first node, and dropping the data bundle from memory of the first node; transmitting the data bundle from the first node towards a second node of the plurality of nodes via a number of communication links, storing the data bundle at the first node, and dropping the data bundle from memory of the first node; wherein transmitting the data bundle from the first node towards the second node of the plurality of nodes via the number of communication links comprises determining that the number of communication links is two or more, based on the context information indicative of quality of communication of the first node with neighbor nodes of the plurality of nodes.
An electromagnetic relay , comprising: a movable terminal including a movable contact ; a fixed terminal including a fixed contact that faces the movable contact , characterised in that it further comprises: two separate first irons disposed apart from each other on one of the fixed terminal and the movable terminal ; and a second iron disposed on another one of the fixed terminal and the movable terminal such that the second iron faces the first irons in a first direction, wherein in plan view seen from the first direction, the second iron partially overlaps both of the first irons . a movable terminal including a movable contact ; a fixed terminal including a fixed contact that faces the movable contact , characterised in that it further comprises: two separate first irons disposed apart from each other on one of the fixed terminal and the movable terminal ; and a second iron disposed on another one of the fixed terminal and the movable terminal such that the second iron faces the first irons in a first direction, wherein two separate first irons disposed apart from each other on one of the fixed terminal and the movable terminal ; and a second iron disposed on another one of the fixed terminal and the movable terminal such that the second iron faces the first irons in a first direction, wherein in plan view seen from the first direction, the second iron partially overlaps both of the first irons .
A method, in a source base station , for providing a handover for a sub-set of bearers associated with a wireless terminal being served by the source base station, said sub-set of bearers being less than all bearers associated with the wireless terminal, the source base station being comprised in a wireless communications network, the method comprising: determining a need for a handover procedure; selecting the sub-set of bearers associated with the wireless terminal; and sending , by the source base station , to a target base station , a handover request for the sub-set of bearers, characterised in that at least one signaling radio bearer, SRB, of the wireless terminal remains connected to the source base station. determining a need for a handover procedure; selecting the sub-set of bearers associated with the wireless terminal; and sending , by the source base station , to a target base station , a handover request for the sub-set of bearers, characterised in that at least one signaling radio bearer, SRB, of the wireless terminal remains connected to the source base station.
A parking enforcement system configured to impair the view of a driver through a windshield of a vehicle , comprising: a plurality of covering assemblies , each of the covering assemblies having one or more suction assemblies configured for placement against a windshield of a vehicle ; a pump assembly configured for pneumatic communication with the one or more suction assemblies , the pump assembly configured to develop a partial vacuum between the suction assemblies and the windshield ; and a release assembly configured for pneumatic communication with the one or more suction assemblies , characterized in that each of the suction assemblies is positioned within a support ring , each of the support rings having a rim , wherein with the parking enforcement system in an installed arrangement, each of the rims is in contact with the windshield of the vehicle , and the release assembly having a servo motor configured to actuate release of the suction assemblies from the windshield . a plurality of covering assemblies , each of the covering assemblies having one or more suction assemblies configured for placement against a windshield of a vehicle ; a pump assembly configured for pneumatic communication with the one or more suction assemblies , the pump assembly configured to develop a partial vacuum between the suction assemblies and the windshield ; and a release assembly configured for pneumatic communication with the one or more suction assemblies , characterized in that each of the suction assemblies is positioned within a support ring , each of the support rings having a rim , wherein with the parking enforcement system in an installed arrangement, each of the rims is in contact with the windshield of the vehicle , and the release assembly having a servo motor configured to actuate release of the suction assemblies from the windshield .
A method of screening a cereblon modifying compound for treating a disease or disorder, comprising: (a) determining the interaction between SALL4 and cereblon in a sample to which the cereblon modifying compound has been administered; and (b) selecting the cereblon modifying compound that does not induce the interaction between SALL4 and cereblon or the cereblon modifying compound that induces reduced interaction between SALL4 and cereblon as compared with a reference compound, wherein the interaction between SALL4 and cereblon is determined by the interaction between amino acid residues 405-432 of SALL4 protein (SEQ ID NO:3) and cereblon or by the interaction between amino acid residues 410-432 of SALL4 protein (SEQ ID NO: 11) and cereblon. (a) determining the interaction between SALL4 and cereblon in a sample to which the cereblon modifying compound has been administered; and (b) selecting the cereblon modifying compound that does not induce the interaction between SALL4 and cereblon or the cereblon modifying compound that induces reduced interaction between SALL4 and cereblon as compared with a reference compound,
A fluid analyzer that analyzes a sample , the fluid analyzer comprising: an analyzer frame ; a test cell assembly that receives the sample; a laser assembly that generates a laser beam; a signal detector assembly ; and a self-check assembly that includes (i) a check frame ; (ii) a check substance coupled to the check frame; (iii) a first check director coupled to the check frame, wherein the first check director is a mirror; and (iv) a check frame mover that selectively moves the check frame and the first check director between a self-check position and a test position relative to the analyzer frame ; wherein in the self-check position, the first check director is positioned in the path of and redirects the laser beam so that the laser beam is directed through the check substance to create a check signal light that is collected by the signal detector assembly to evaluate the performance of the fluid analyzer; and wherein in the test position, the first check director is positioned outside the path of the laser beam and the laser beam is directed through the sample in the test cell assembly to create a test signal light that is collected by the signal detector assembly to evaluate the sample. an analyzer frame ; a test cell assembly that receives the sample; a laser assembly that generates a laser beam; a signal detector assembly ; and a self-check assembly that includes (i) a check frame ; (ii) a check substance coupled to the check frame; (iii) a first check director coupled to the check frame, wherein the first check director is a mirror; and (iv) a check frame mover that selectively moves the check frame and the first check director between a self-check position and a test position relative to the analyzer frame ; wherein in the self-check position, the first check director is positioned in the path of and redirects the laser beam so that the laser beam is directed through the check substance to create a check signal light that is collected by the signal detector assembly to evaluate the performance of the fluid analyzer; and wherein in the test position, the first check director is positioned outside the path of the laser beam and the laser beam is directed through the sample in the test cell assembly to create a test signal light that is collected by the signal detector assembly to evaluate the sample.
A sheet detection device configured to detect a sheet that comprises a transparent portion and is transported along a transport path , the device comprising: at least one ultraviolet light source configured to apply ultraviolet light to the transport path ; at least one photodetector configured to detect the ultraviolet light applied by the at least one ultraviolet light source and transmitted through the sheet ; and a detector configured to detect at least one of passage, arrival, or presence of the sheet based on an output signal from the photodetector , the detector being configured to detect the sheet based on an attenuation rate of the output signal from the photodetector , based on characteristics that the sheet has a low ultraviolet light transmittance in the transparent portion in the direction in which ultraviolet light travels as compared with a case when no sheet is present in the direction in which ultraviolet light travels, and that the sheet has a transmittance of ultraviolet light having a wavelength of 280 nm of approximately 70% or lower in the transparent portion in the direction in which ultraviolet light travels. at least one ultraviolet light source configured to apply ultraviolet light to the transport path ; at least one photodetector configured to detect the ultraviolet light applied by the at least one ultraviolet light source and transmitted through the sheet ; and a detector configured to detect at least one of passage, arrival, or presence of the sheet based on an output signal from the photodetector , the detector being configured to detect the sheet based on an attenuation rate of the output signal from the photodetector , based on characteristics that the sheet has a low ultraviolet light transmittance in the transparent portion in the direction in which ultraviolet light travels as compared with a case when no sheet is present in the direction in which ultraviolet light travels, and that the sheet has a transmittance of ultraviolet light having a wavelength of 280 nm of approximately 70% or lower in the transparent portion in the direction in which ultraviolet light travels.
A system for verifying a face of a user registered in a user DataBase, DB, by using a light mask, comprising: an image input unit for receiving a specific facial image and transmitting the specific facial image to a facial feature extraction unit ; the facial feature extraction unit for extracting (S720) a facial feature vector from an entire facial area of the specific facial image as a single extraction unit; a non-user Gaussian Mixture Model, GMM, configuration unit for generating a non-user GMM from a non-user facial image of a non-user registered in a non-user DataBase, DB, and for storing the non-user GMM in the non-user DataBase, DB ; a user GMM configuration unit for generating (S730) and storing a user GMM in the user DB , wherein generating the user GMM comprises increasing the number of facial feature vectors by combining a user facial image of the user registered in the user DB with a plurality of light masks having an effect of directing illumination in various directions to create various facial images illuminated in various directions and generating the user GMM on the basis of the increased number of facial feature vectors and the non-user GMM; a log-likelihood value calculation unit for inputting the facial feature vector both to the non-user GMM and to the user GMM, thus calculating log- likelihood values (S740); and a user verification unit for comparing the calculated log-likelihood values with a predetermined threshold, thus verifying (S750) whether the specific facial image is a facial image of the user. an image input unit for receiving a specific facial image and transmitting the specific facial image to a facial feature extraction unit ; the facial feature extraction unit for extracting (S720) a facial feature vector from an entire facial area of the specific facial image as a single extraction unit; a non-user Gaussian Mixture Model, GMM, configuration unit for generating a non-user GMM from a non-user facial image of a non-user registered in a non-user DataBase, DB, and for storing the non-user GMM in the non-user DataBase, DB ; a user GMM configuration unit for generating (S730) and storing a user GMM in the user DB , wherein generating the user GMM comprises increasing the number of facial feature vectors by combining a user facial image of the user registered in the user DB with a plurality of light masks having an effect of directing illumination in various directions to create various facial images illuminated in various directions and generating the user GMM on the basis of the increased number of facial feature vectors and the non-user GMM; a log-likelihood value calculation unit for inputting the facial feature vector both to the non-user GMM and to the user GMM, thus calculating log- likelihood values (S740); and a user verification unit for comparing the calculated log-likelihood values with a predetermined threshold, thus verifying (S750) whether the specific facial image is a facial image of the user.