mhurhangee/patent-ind-claim-en huggingface dataset:
A method of modifying a non-human organism by manipulation of a target sequence in a genomic locus of interest comprising delivering a non-naturally occurring or engineered composition comprising a viral vector system comprising one or more viral vectors comprising one or more polynucleotides encoding the CRISPR-Cas system, the CRISPR-Cas system comprising a CRISPR enzyme comprising at least one or more nuclear localization sequences; a guide sequence capable of hybridizing to a target sequence in a eukaryotic cell; a tracr mate sequence; and a tracr sequence wherein said non-naturally occurring or engineered composition is delivered to a post-mitotic brain cell; and wherein the method is not a method of treatment or diagnosis.
A power converter for converting a DC input into an AC output for supply to a utility grid, the converter comprising: switching circuitry connected across a pair of DC supply lines and arranged to generate pulsed outputs at a switching frequency; and a controller configured to operate the switching circuitry to generate pulsed outputs at the switching frequency on a plurality of output lines corresponding to different phases of a multi-phase utility grid, the controller being responsive to the detection of an electrical disturbance in the utility grid when a grid voltage drops below a predetermined threshold, characterised in that the controller is responsive to the detection of an electrical disturbance in one phase of the utility grid to increase the switching frequency only in relation to the pulsed outputs to be provided to the output line corresponding to the disturbed phase. switching circuitry connected across a pair of DC supply lines and arranged to generate pulsed outputs at a switching frequency; and a controller configured to operate the switching circuitry to generate pulsed outputs at the switching frequency on a plurality of output lines corresponding to different phases of a multi-phase utility grid, the controller being responsive to the detection of an electrical disturbance in the utility grid when a grid voltage drops below a predetermined threshold, characterised in that the controller is responsive to the detection of an electrical disturbance in one phase of the utility grid to increase the switching frequency only in relation to the pulsed outputs to be provided to the output line corresponding to the disturbed phase.
A semiconductor die , comprising a vertical power transistor device , the vertical power transistor device having a source region and a drain region at opposite sides (10.a, 10.b) of a semiconductor body , forming a load terminal respectively, and a gate electrode (5.1); a pull-down transistor device , the pull-down transistor device having a control terminal and being switchable between a conducting state and a blocking state via the control terminal , and a capacitor (C), wherein the pull-down transistor device is connected between the gate electrode (5.1) of the vertical power transistor device and a ground terminal and connects the gate electrode (5.1) to the ground terminal in the conducting state, and wherein the capacitor (C) is connected between one of the load terminals of the vertical power transistor device and the control terminal of the pull-down transistor device and capacitively couples the one load terminal to the control terminal , characterized in that a second capacitor electrode of the capacitor (C), which is connected to the control terminal of the pull-down transistor device , comprises a trench electrode formed in a capacitor trench in the semiconductor body . a vertical power transistor device , the vertical power transistor device having a source region and a drain region at opposite sides (10.a, 10.b) of a semiconductor body , forming a load terminal respectively, and a gate electrode (5.1); a pull-down transistor device , the pull-down transistor device having a control terminal and being switchable between a conducting state and a blocking state via the control terminal , and a capacitor (C), wherein the pull-down transistor device is connected between the gate electrode (5.1) of the vertical power transistor device and a ground terminal and connects the gate electrode (5.1) to the ground terminal in the conducting state, and wherein the capacitor (C) is connected between one of the load terminals of the vertical power transistor device and the control terminal of the pull-down transistor device and capacitively couples the one load terminal to the control terminal , characterized in that a second capacitor electrode of the capacitor (C), which is connected to the control terminal of the pull-down transistor device , comprises a trench electrode formed in a capacitor trench in the semiconductor body .
A refuse container apparatus for an underground refuse collecting arrangement , having a refuse collecting container which comprises a lid element that closes off the refuse collecting container at the top, wherein a receiving opening for refuse is provided in said lid element , with a handling device for the refuse container apparatus and with a drop-in housing for refuse that is provided above the receiving opening , that is releasably connected or adapted to be connected to the lid element , said drop-in housing comprising a drop-in chute , wherein at least one drop-in opening for refuse is provided in said drop-in chute , characterised in that the receiving opening in the lid element has a diameter (X) that is greater than the dimension (Y) of the cross-section of the drop-in chute , and that the drop-in housing comprises a flange connection in the lower end region of the drop-in chute , which releasably connects the drop-in housing to the lid element by making contact with the lid element from inside the refuse collecting container by having the drop-in housing being pulled out from the interior of the refuse collecting container through the receiving opening .
Drainage actuation device for drain valves of bathtubs, washbasins and sinks with an actuation element , which is operable in a rotatory manner and by which the drain valve can be transferred from a closed position to an open position and from an open position to a closed position, characterised in that return means are provided for the actuation element , so that following actuation of the drain valve from the closed position to the open position and from the open position to the closed position, the actuation element returns autonomously to a starting position.
A user equipment , comprising: a reception unit configured to receive higher layer signaling including first information relating to a measurement object; and a measurement unit configured to perform, based on the measurement object, a Radio Resource Management, RRM, measurement; wherein in a case where the measurement object indicates a Channel State Information reference signal, CSI-RS, measurement, the first information includes a first parameter indicating a subcarrier spacing of the CSI-RS that is used for the RRM measurement. a reception unit configured to receive higher layer signaling including first information relating to a measurement object; and a measurement unit configured to perform, based on the measurement object, a Radio Resource Management, RRM, measurement; wherein in a case where the measurement object indicates a Channel State Information reference signal, CSI-RS, measurement, the first information includes a first parameter indicating a subcarrier spacing of the CSI-RS that is used for the RRM measurement.
Apparatus for making a technical netting comprising - at least a belt manufacturing unit , and - a knitting machine , wherein - the belt manufacturing unit is configured to manufacture an endless belt strap , - the knitting machine having at least a belt strap feeding unit , which is configured to feed the belt strap provided by the belt manufacturing unit to the knitting machine , and - the knitting machine having at least a knitting unit to knit a thread group with a belt strap section of the fed belt strap to manufacture a technical netting with crossing belt straps and knitting straps characterized in that the at least one knitting unit is movable transversely to the processing direction and/or in processing direction . - at least a belt manufacturing unit , and - a knitting machine , - the belt manufacturing unit is configured to manufacture an endless belt strap , - the knitting machine having at least a belt strap feeding unit , which is configured to feed the belt strap provided by the belt manufacturing unit to the knitting machine , and - the knitting machine having at least a knitting unit to knit a thread group with a belt strap section of the fed belt strap to manufacture a technical netting with crossing belt straps and knitting straps
A hearing aid device configured to communicate wirelessly with an external device where the hearing aid device comprises a housing with a microphone and an amplifier , where the hearing aid device further comprises an antenna and: further comprising a hook provided with a through-going bore configured to deliver air-borne sound acoustically from a receiver in the housing to an ear mould or dome via a tube connected to the hook, the tube configured to be attached to the distal end of the hook , wherein the antenna extends along a portion of the hook and that the antenna is embedded into the wall of the hook . further comprising a hook provided with a through-going bore configured to deliver air-borne sound acoustically from a receiver in the housing to an ear mould or dome via a tube connected to the hook, the tube configured to be attached to the distal end of the hook , wherein the antenna extends along a portion of the hook and that the antenna is embedded into the wall of the hook .
Method for determining a driving behavior of a driver in relation to a driving behavior of an automated driving system of a vehicle , characterized in that during a manual driving operation of the vehicle - actuating commands (SB) from the driver and a manually driven trajectory (r) of the vehicle are detected, - in a first calculation path (R1), it is determined which automated actuating commands the automated driving system would generate at a current actual position of the vehicle on the manually driven trajectory (r) if the automated driving system were active, - in a second calculation path (R2), a trajectory (β, β', β 0 to β 2 ) of the vehicle , which the vehicle would cover when the automated driving system is active, is simulated, and - depending on the detected actuating commands (SB) from the driver as well as the automated actuating commands and/or the manually driven trajectory (r) as well as the simulated trajectory (β, β', β 0 to β 2 ), at least one score value (SW1 to SW4) is determined as a measure of a discrepancy between the driving behavior of the driver and the driving behavior of the automated driving system, the score value (SW1 to SW4) being determined based on a probability that the automated driving system would have, at an earlier point in time (t 0 , t 1 , t 2 ), specified a trajectory (β, β', β 0 to β 2 ) which at least substantially corresponds to the manually driven trajectory (r) as the target trajectory. - actuating commands (SB) from the driver and a manually driven trajectory (r) of the vehicle are detected, - in a first calculation path (R1), it is determined which automated actuating commands the automated driving system would generate at a current actual position of the vehicle on the manually driven trajectory (r) if the automated driving system were active, - in a second calculation path (R2), a trajectory (β, β', β 0 to β 2 ) of the vehicle , which the vehicle would cover when the automated driving system is active, is simulated, and - depending on the detected actuating commands (SB) from the driver as well as the automated actuating commands and/or the manually driven trajectory (r) as well as the simulated trajectory (β, β', β 0 to β 2 ), at least one score value (SW1 to SW4) is determined as a measure of a discrepancy between the driving behavior of the driver and the driving behavior of the automated driving system, the score value (SW1 to SW4) being determined based on a probability that the automated driving system would have, at an earlier point in time (t 0 , t 1 , t 2 ), specified a trajectory (β, β', β 0 to β 2 ) which at least substantially corresponds to the manually driven trajectory (r) as the target trajectory.
A compound represented by the following general formula (1-4): wherein R 1 is a single bond or a 2n-valent group of 1 to 30 carbon atoms; each R 4 is independently a halogen atom, a linear, branched, or cyclic alkyl group of 1 to 10 carbon atoms, an aryl group of 6 to 10 carbon atoms, an alkenyl group of 2 to 10 carbon atoms, an alkoxy group of 1 to 30 carbon atoms, or a thiol group; each m 4 is independently an integer of 0 to 5; provided that at least one selected from the group consisting of R 1 and R 4 is a group containing an iodine atom.
An apparatus for treating reflux disease in a human or animal mammal patient, characterized in that the apparatus comprises two or more separate movement restriction device segments (561a - 561d) adapted to be placed in contact with each other and be assembled in situ to an implantable assembled movement restriction device (560; 561) of a controlled size, wherein the assembled movement restriction device is adapted to rest with at least a part of its outer surface against the patient's stomach fundus wall such that movement of the cardiac notch of the patient's stomach towards the patient's diaphragm is restricted, when the movement restriction device is implanted in the patient, to thereby prevent the cardia from sliding through the patient's diaphragm opening into the patient's thorax, so as to maintain the supporting pressure against the patient's cardia sphincter muscle exerted from the patient's abdomen.
A method of identifying a cervical cell as neoplastic or predisposed to neoplasia in an isolated sample, comprising determining the methylation status of at least three marker genes selected from the group consisting of KCNIP4, GATA4, GFRA1, ST6GALNAC5, CDH6, ZSCAN1, ANKRD18CP and LHX8.
- A method for treating pea soluble fractions, comprising: a) a step of preparation of soluble fractions comprising (i) the preparation of a starch milk, by mixing pea flour and water in a kneading machine, (ii) the preparation of a protein-rich product by extraction of the starch and the fibers from said starch milk from step i), (iii) a flocculation operation on said protein-rich product from step ii); (iv) a separation operation of the product obtained from step iii) to obtain a floc and a supernatant called soluble fractions, b) a step of microfiltration or centrifugation of said soluble fractions resulting in a microfiltration permeate or a centrifugation supernatant, c) followed by a step of ultrafiltration of the microfiltration permeate or of the centrifugation supernatant, resulting in an ultrafiltration permeate and an ultrafiltration retentate, d) followed by an optional step of reverse osmosis of said ultrafiltration permeate, resulting in a permeate and a retentate from the reverse osmosis, e) a step of redirection of all or part of said microfiltration permeate, microfiltration retentate, ultrafiltration retentate, and/or reverse osmosis retentate to the floc, downstream of the separation step of the product obtained from step iii), wherein the globulins and phytic acid are recovered in the microfiltration retentate or the centrifugation pellet. a) a step of preparation of soluble fractions comprising (i) the preparation of a starch milk, by mixing pea flour and water in a kneading machine, (ii) the preparation of a protein-rich product by extraction of the starch and the fibers from said starch milk from step i), (iii) a flocculation operation on said protein-rich product from step ii); (iv) a separation operation of the product obtained from step iii) to obtain a floc and a supernatant called soluble fractions, (i) the preparation of a starch milk, by mixing pea flour and water in a kneading machine, (ii) the preparation of a protein-rich product by extraction of the starch and the fibers from said starch milk from step i), (iii) a flocculation operation on said protein-rich product from step ii); (iv) a separation operation of the product obtained from step iii) to obtain a floc and a supernatant called soluble fractions, b) a step of microfiltration or centrifugation of said soluble fractions resulting in a microfiltration permeate or a centrifugation supernatant, c) followed by a step of ultrafiltration of the microfiltration permeate or of the centrifugation supernatant, resulting in an ultrafiltration permeate and an ultrafiltration retentate, d) followed by an optional step of reverse osmosis of said ultrafiltration permeate, resulting in a permeate and a retentate from the reverse osmosis, e) a step of redirection of all or part of said microfiltration permeate, microfiltration retentate, ultrafiltration retentate, and/or reverse osmosis retentate to the floc, downstream of the separation step of the product obtained from step iii),
An apparatus for pyrolysing or gasifying material containing an organic content; the apparatus comprising: an oven mounted for rotation on at least one support , said oven having an inlet for receiving hot gas having a low or zero oxygen content to heat the material therein so as to process it to produce syngas, and an outlet for said syngas; an electromagnet disposed in or adjacent said oven so as to create a magnetic field therein; a plurality of ferrous elements freely disposed within the oven ; and control means for controlling the electromagnet and the rotation of the oven such that when activated said electromagnet retains said ferrous elements as the oven rotates; characterised in that the apparatus further comprises at least one gas analyser configured to analyse the composition of the gas exiting said oven ; and wherein the control means is configured to receive signals from said gas analyser and when said signals indicate that processing of the material in said oven is substantially complete, control the electromagnet to release the ferrous elements when they are substantially at the top of the oven's rotation. an oven mounted for rotation on at least one support , said oven having an inlet for receiving hot gas having a low or zero oxygen content to heat the material therein so as to process it to produce syngas, and an outlet for said syngas; an electromagnet disposed in or adjacent said oven so as to create a magnetic field therein; a plurality of ferrous elements freely disposed within the oven ; and control means for controlling the electromagnet and the rotation of the oven such that when activated said electromagnet retains said ferrous elements as the oven rotates; characterised in that the apparatus further comprises at least one gas analyser configured to analyse the composition of the gas exiting said oven ; and wherein the control means is configured to receive signals from said gas analyser and when said signals indicate that processing of the material in said oven is substantially complete, control the electromagnet to release the ferrous elements when they are substantially at the top of the oven's rotation.
Dirt collecting device for a cleaning appliance in the form of a sweeping vehicle consisting of a housing driven to be displaceable over the roadway plane and in which is arranged at least one rotatably driven sweeping roller which removes the coarse dirt and fine dirt from the roadway plane and supported by a suction air stream of a suction fan conveys it into a collection container , wherein an intermediate container lying in the suction air stream of the suction fan for temporary intermediate storage of coarse dirt is arranged in the housing of the dirt collecting device , characterised in that the suction fan can be regulated in speed and/or power and is designed for carrying out the following steps: 1.1 in a first step, which corresponds to normal operation, the suction power of the suction fan is set so low that the suction pressure in the dirt collecting device is just sufficient in order to convey the picked-up coarse dirt into the intermediate container and to store it there and to convey the picked-up fine dirt into a downstream collection container , 1.2 in a second step, the filling level in the intermediate container is recorded with regard to the coarse dirt stored there, 1.3 in a third method step, which corresponds to an emptying operation, on exceeding the filling level in the intermediate container , the suction power of the suction fan is increased such that the coarse dirt stored temporarily in the intermediate container becomes dispersible and is conveyed into the downstream collection container (4 and/or 6). 1.1 in a first step, which corresponds to normal operation, the suction power of the suction fan is set so low that the suction pressure in the dirt collecting device is just sufficient in order to convey the picked-up coarse dirt into the intermediate container and to store it there and to convey the picked-up fine dirt into a downstream collection container , 1.2 in a second step, the filling level in the intermediate container is recorded with regard to the coarse dirt stored there, 1.3 in a third method step, which corresponds to an emptying operation, on exceeding the filling level in the intermediate container , the suction power of the suction fan is increased such that the coarse dirt stored temporarily in the intermediate container becomes dispersible and is conveyed into the downstream collection container (4 and/or 6).