mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of Formula I: or a pharmaceutically acceptable salt or a stereoisomer thereof, for use in a method of treating a disease or disorder associated with PD-1/PD-L1 interaction in combination with one or more other therapies, wherein the disease or disorder is cancer or an infection, wherein: R 1 is methyl, CN, F, Cl, or Br; R 2 is methyl, CN, F, Cl, or Br; and R 3 is H, C 1-4 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-2 alkyl-, C 6-10 aryl, C 6-10 aryl-C 1-2 alkyl, 5- to 6-membered heteroaryl, 5- to 6-membered heteroaryl-C 1-2 alkyl, 4- to 6-membered heterocycloalkyl or 4- to 6-membered heterocycloalkyl-C 1-2 alkyl-, wherein the 5- to 6-membered heteroaryl, 5- to 6-membered heteroaryl-C 1-2 alkyl, 4- to 6-membered heterocycloalkyl and 4- to 6-membered heterocycloalkyl-C 1-2 alkyl- each has one or two heteroatoms as ring members selected from O, N and S, and wherein the C 1-4 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-2 alkyl-, C 6-10 aryl, C 6-10 aryl-C 1-2 alkyl, 5- to 6-membered heteroaryl, 5- to 6-membered heteroaryl-C 1-2 alkyl, 4- to 6-membered heterocycloalkyl and 4- to 6-membered heterocycloalkyl-C 1-2 alkyl- of R 3 are each optionally substituted with 1 or 2 substituents independently selected from CONH 2 , SO 2 NH 2 , COOH, OH, CON(CH 3 ) 2 , CH 3 , F, Cl, Br, CN, ethyl, and propyl. R 1 is methyl, CN, F, Cl, or Br; R 2 is methyl, CN, F, Cl, or Br; and R 3 is H, C 1-4 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-2 alkyl-, C 6-10 aryl, C 6-10 aryl-C 1-2 alkyl, 5- to 6-membered heteroaryl, 5- to 6-membered heteroaryl-C 1-2 alkyl, 4- to 6-membered heterocycloalkyl or 4- to 6-membered heterocycloalkyl-C 1-2 alkyl-, wherein the 5- to 6-membered heteroaryl, 5- to 6-membered heteroaryl-C 1-2 alkyl, 4- to 6-membered heterocycloalkyl and 4- to 6-membered heterocycloalkyl-C 1-2 alkyl- each has one or two heteroatoms as ring members selected from O, N and S, and wherein the C 1-4 alkyl, C 3-8 cycloalkyl, C 3-8 cycloalkyl-C 1-2 alkyl-, C 6-10 aryl, C 6-10 aryl-C 1-2 alkyl, 5- to 6-membered heteroaryl, 5- to 6-membered heteroaryl-C 1-2 alkyl, 4- to 6-membered heterocycloalkyl and 4- to 6-membered heterocycloalkyl-C 1-2 alkyl- of R 3 are each optionally substituted with 1 or 2 substituents independently selected from CONH 2 , SO 2 NH 2 , COOH, OH, CON(CH 3 ) 2 , CH 3 , F, Cl, Br, CN, ethyl, and propyl.
A method for participating in beam management, the method being performed by a radio transceiver device , the method comprising: receiving (S102) a reference signal from another radio transceiver device as part of participating in the beam management, wherein the reference signal occupies time/frequency resources that extend over a first frequency interval, wherein the reference signal is received in a reception beam , and wherein the reception beam has a frequency-dependent polarization over the first frequency interval, and wherein the frequency-dependent polarization changes over the first frequency interval, characterized in that the reference signal is received using a first antenna element set of a first polarization and, with a time delay value δ, at a second antenna element set of a second polarization, the time delay value δ causing the frequency-dependent polarization over the first frequency interval, and in that the time delay value δ is implemented in a time delay component in the radio transceiver device . receiving (S102) a reference signal from another radio transceiver device as part of participating in the beam management, wherein the reference signal occupies time/frequency resources that extend over a first frequency interval, wherein the reference signal is received in a reception beam , and wherein the reception beam has a frequency-dependent polarization over the first frequency interval, and wherein the frequency-dependent polarization changes over the first frequency interval, characterized in that the reference signal is received using a first antenna element set of a first polarization and, with a time delay value δ, at a second antenna element set of a second polarization, the time delay value δ causing the frequency-dependent polarization over the first frequency interval, and in that the time delay value δ is implemented in a time delay component in the radio transceiver device .
A method for information display, comprising: specifying information pertaining to a target location; encoding the specified information in a machine-readable symbol comprising a set of three or more color elements , which have different, respective colors that encode a first part of the information and are contained within a non-rectangular border , which has a shape characteristic that encodes a second part of the information; and positioning the symbol in the target location. specifying information pertaining to a target location; encoding the specified information in a machine-readable symbol comprising a set of three or more color elements , which have different, respective colors that encode a first part of the information and are contained within a non-rectangular border , which has a shape characteristic that encodes a second part of the information; and positioning the symbol in the target location.
A wound care system for reduced pressure therapy comprising a covering device that can be fixed to the skin surrounding a wound and serving to produce a closed wound space containing the wound and a valve system, , said valve system being assigned to the covering device, and said valve system being operable on the one hand to suck gases out of the wound space and on the other hand to counter the penetration of gases into the wound space after fixing the covering device to the skin surrounding the wound, the valve system being able to be coupled detachably to a suction device that can be operated to suck gases out of the wound space, characterised in that the valve system comprises a film valve.
A vent for venting exhaust gases from a component of a respiratory therapy system, the vent comprising: a substrate having an inner surface and an outer surface; and a plurality of vent holes arranged in a vent hole array extending through the substrate, each vent hole comprising an exhaust gas inlet at the inner surface of the substrate and an exhaust gas outlet at an outer surface of the substrate , the exhaust gas inlet and the exhaust gas outlet each having a respective centre; wherein the exhaust gas inlet and the exhaust gas outlet define a draft direction being the direction that exhausted air flows out of each of the vent holes and which is defined by an axis that extends through the centre of the exhaust gas inlet and the centre of the exhaust gas outlet of each of the vent holes ; wherein the draft direction of at least some of the vent holes is not aligned with a draw direction , the draw direction , being the direction at which a mould tool is opened or removed relative to the vent during manufacture; wherein the vent holes have the same draw direction ; at least one vent hole has a different draft direction from at least one other vent hole ; the vent hole(s) further from a centre of the vent have a draft direction which is inclined at a greater angle from the draw direction relative to the vent hole(s) nearer the centre of the vent ; and the exhaust gas outlet of each vent hole has a larger diameter than the exhaust gas inlet . a substrate having an inner surface and an outer surface; and a plurality of vent holes arranged in a vent hole array extending through the substrate, each vent hole comprising an exhaust gas inlet at the inner surface of the substrate and an exhaust gas outlet at an outer surface of the substrate , the exhaust gas inlet and the exhaust gas outlet each having a respective centre; wherein the exhaust gas inlet and the exhaust gas outlet define a draft direction being the direction that exhausted air flows out of each of the vent holes and which is defined by an axis that extends through the centre of the exhaust gas inlet and the centre of the exhaust gas outlet of each of the vent holes ; wherein the draft direction of at least some of the vent holes is not aligned with a draw direction , the draw direction , being the direction at which a mould tool is opened or removed relative to the vent during manufacture; wherein the vent holes have the same draw direction ; at least one vent hole has a different draft direction from at least one other vent hole ; the vent hole(s) further from a centre of the vent have a draft direction which is inclined at a greater angle from the draw direction relative to the vent hole(s) nearer the centre of the vent ; and the exhaust gas outlet of each vent hole has a larger diameter than the exhaust gas inlet .
A positron tomography imaging apparatus for a multiphase flow in an oil pipeline, the positron tomography imaging apparatus comprising at least one set of probes configured to produce positron and electron annihilation and detect time-coincidence gamma ray events, wherein each set of probes comprises a pair of parallel gamma-ray detector arrays , a positron radioactive source and a radioactive source shield , characterized in that, the pair of parallel gamma-ray detector arrays are configured to be respectively disposed on both sides of an oil pipeline under detection and perpendicular to an axial direction of the oil pipeline , the positron radioactive source configured to be located between the oil pipeline and a row of gamma-ray detector arrays in the pair of parallel gamma-ray detector arrays and parallel to the pair of parallel gamma-ray detector arrays , the radioactive source shield configured to undertake a gap shielding of the positron radioactive source in the axial direction of the oil pipeline , the pair of parallel gamma-ray detector arrays included in the each set of probes configured to determine plurality of detection intervals, each of which is determined by a pair of gamma-ray detectors, an average absorption coefficient of gamma-ray being acquired from each detection interval such that average absorption coefficients of different detection intervals acquired simultaneously may be used to reconstruct a tomography image of fluid.
A protective helmet, particularly for cyclists or motorcyclists, comprising a helmet body forming a protective shell adapted to be worn on the head of a user, a face visor mounted to the helmet body and adapted to be placed in front of the face of the user, said face visor being capable of defining, with the helmet body , an inner space adapted to receive the head of the user, an air inlet formed on the helmet body and adapted to convey air from the external environment towards said inner space, an air filter arranged at said air inlet, a ventilation system configured to purify the air in said inner space, said ventilation system comprising - an air outlet formed on the helmet body , and through which said inner space is in fluid communication with the external environment, and characterised by further comprising - a carbon dioxide sensor configured to provide a signal indicative of the concentration of carbon dioxide in the air in said inner space, and - an electric fan arranged at the air outlet and configured to suck the air from said inner space and discharge it into the external environment, said electric fan being operable as a function of the signal provided by the carbon dioxide sensor . a helmet body forming a protective shell adapted to be worn on the head of a user, a face visor mounted to the helmet body and adapted to be placed in front of the face of the user, said face visor being capable of defining, with the helmet body , an inner space adapted to receive the head of the user, an air inlet formed on the helmet body and adapted to convey air from the external environment towards said inner space, an air filter arranged at said air inlet, a ventilation system configured to purify the air in said inner space, said ventilation system comprising - an air outlet formed on the helmet body , and through which said inner space is in fluid communication with the external environment, and characterised by further comprising - a carbon dioxide sensor configured to provide a signal indicative of the concentration of carbon dioxide in the air in said inner space, and - an electric fan arranged at the air outlet and configured to suck the air from said inner space and discharge it into the external environment, said electric fan being operable as a function of the signal provided by the carbon dioxide sensor . - an air outlet formed on the helmet body , and through which said inner space is in fluid communication with the external environment, and characterised by further comprising - a carbon dioxide sensor configured to provide a signal indicative of the concentration of carbon dioxide in the air in said inner space, and - an electric fan arranged at the air outlet and configured to suck the air from said inner space and discharge it into the external environment, said electric fan being operable as a function of the signal provided by the carbon dioxide sensor .
An ignitor for use in a wellbore, the ignitor comprising: - a housing ; - a compartment provided within the housing ; - a first exothermic mixture of at least a metal and an oxide provided in the compartment , wherein the first exothermic mixture comprises fine-grained particles of metal and oxide particles having a particle size between 0.1 and 1 mm; - a first electrode connectable to a first terminal of a power supply; - a second electrode (4") connectable to a second terminal of the power supply; where at least parts of the first and second electrodes (4', 4") are in contact with the first exothermic mixture ; where the first electrode and the second electrode (4") are provided at a distance (d) from each other, wherein, upon appliance of a voltage above a predetermined threshold value between the first and second electrodes (4', 4"), an electromagnetic field is created in the first exothermic mixture between the first and second electrodes (4', 4"). - a housing ; - a compartment provided within the housing ; - a first exothermic mixture of at least a metal and an oxide provided in the compartment , wherein the first exothermic mixture comprises fine-grained particles of metal and oxide particles having a particle size between 0.1 and 1 mm; - a first electrode connectable to a first terminal of a power supply; - a second electrode (4") connectable to a second terminal of the power supply; where at least parts of the first and second electrodes (4', 4") are in contact with the first exothermic mixture ;
An aerosol-generating device comprising: a cavity for receiving an aerosol-generating article comprising an aerosol-forming substrate, wherein the cavity comprises a base , wherein the base comprises at least one air aperture ; an induction heating arrangement, wherein the induction heating arrangement comprises a susceptor arrangement and an induction coil , wherein the induction heating arrangement is arranged at least partly surrounding or forming the cavity; and a thermally insulating element , wherein the thermally insulating element is arranged between the susceptor arrangement and the induction coil, and wherein the thermally insulating element is sealingly attached to the base to prevent lateral airflow in a direction perpendicular to a longitudinal axis of the aerosol-generating device into the cavity at the base of the cavity, and wherein one or more sidewalls of the susceptor arrangement are permeable for lateral airflow to enter the cavity in a direction perpendicular to the longitudinal axis of the aerosol-generating device. a cavity for receiving an aerosol-generating article comprising an aerosol-forming substrate, wherein the cavity comprises a base , wherein the base comprises at least one air aperture ; an induction heating arrangement, wherein the induction heating arrangement comprises a susceptor arrangement and an induction coil , wherein the induction heating arrangement is arranged at least partly surrounding or forming the cavity; and a thermally insulating element , wherein the thermally insulating element is arranged between the susceptor arrangement and the induction coil, and wherein the thermally insulating element is sealingly attached to the base to prevent lateral airflow in a direction perpendicular to a longitudinal axis of the aerosol-generating device into the cavity at the base of the cavity, and wherein one or more sidewalls of the susceptor arrangement are permeable for lateral airflow to enter the cavity in a direction perpendicular to the longitudinal axis of the aerosol-generating device.
An Arrangement comprising a device for recording biometric features of a persons' face , having a housing in which a camera having a first focal length for recording the biometric features and an optical mirror for folding a beam path running between the persons' face and the camera are arranged, with an evaluation and/or control unit which is designed to be in a wireless or wired communication connection with a digital mirror which is designed to display the image captured by the camera and which is arranged vertically offset with respect to the optical mirror , and with an illumination device , characterized in that the illumination device comprises a first illumination unit and a second illumination unit , the first illumination unit and the second illumination unit , when the arrangement is prepared for its intended use, being vertically offset with respect to the optical mirror , wherein the first illumination unit is vertically offset in a first direction with respect to the optical mirror , and wherein the second illumination unit is vertically offset in a second direction different from the first direction with respect to the optical mirror , and in that a rear wall is present which is spatially offset from the housing , which on its front side facing the housing comprises a light guide which is designed to couple out light, which has been coupled into it, via the front side of the rear wall , whereas the persons' face being located between the housing and the rear wall , when the arrangement is prepared for its intended use.
A bioerodible drug delivery device comprising a non-woven sheet having a length, width and thickness, said sheet in a rolled configuration comprising multiple turns along an axis parallel to the sheet length and perpendicular to the sheet width, wherein the non-woven sheet comprises a bioerodible polymer and at least one active agent, wherein the non-woven sheet is obtainable by electrospinning a solution comprising the bioerodible polymer at a concentration from 1-100mg/ml; and wherein the active agent is etonogestrel.
An optoelectronic apparatus comprising - an optical device having an optical structure which comprises a plurality of optical elements , and having a concentrator , - a radiation-emitting or radiation-receiving semiconductor chip with a contact structure which comprises a plurality of contact elements for electrically contacting the semiconductor chip and is spaced apart vertically from the optical structure , wherein the contact elements are arranged in interspaces between the optical elements upon a projection of the contact structure into the plane of the optical structure , and wherein - the concentrator has a smaller aperture on a side facing the semiconductor chip than on a side facing away from the semiconductor chip , - the optical structure is arranged on the side of the concentrator facing the semiconductor chip , - the concentrator is a solid body and characterized in that - the concentrator and the optical structure are embodied in one piece. - an optical device having an optical structure which comprises a plurality of optical elements , and having a concentrator , - a radiation-emitting or radiation-receiving semiconductor chip with a contact structure which comprises a plurality of contact elements for electrically contacting the semiconductor chip and is spaced apart vertically from the optical structure , wherein the contact elements are arranged in interspaces between the optical elements upon a projection of the contact structure into the plane of the optical structure , and wherein - the concentrator has a smaller aperture on a side facing the semiconductor chip than on a side facing away from the semiconductor chip , - the optical structure is arranged on the side of the concentrator facing the semiconductor chip , - the concentrator is a solid body and characterized in that - the concentrator and the optical structure are embodied in one piece.
A monitoring system for monitoring a container network interface of a container network namespace , the container network namespace associated with one or more containers , the monitoring system comprising: at least one memory configured to store instructions; and at least one processor disposed in communication with the at least one memory , wherein the at least one processor upon execution of the instructions is configured to: provide a network monitoring application ; use the network monitoring application to receive the container network namespace assigned to the one or more containers as established in a container runtime; switch the network monitoring application from a host network namespace to the container network namespace of the one or more containers; use the network monitoring application to open the container network interface of the container network namespace for allowing access to packets received or transmitted by the container network interface ; and use the network monitoring application to access the packets. at least one memory configured to store instructions; and at least one processor disposed in communication with the at least one memory , wherein the at least one processor upon execution of the instructions is configured to: provide a network monitoring application ; use the network monitoring application to receive the container network namespace assigned to the one or more containers as established in a container runtime; switch the network monitoring application from a host network namespace to the container network namespace of the one or more containers; use the network monitoring application to open the container network interface of the container network namespace for allowing access to packets received or transmitted by the container network interface ; and use the network monitoring application to access the packets. provide a network monitoring application ; use the network monitoring application to receive the container network namespace assigned to the one or more containers as established in a container runtime; switch the network monitoring application from a host network namespace to the container network namespace of the one or more containers; use the network monitoring application to open the container network interface of the container network namespace for allowing access to packets received or transmitted by the container network interface ; and use the network monitoring application to access the packets.