mhurhangee/patent-ind-claim-en huggingface dataset:
A state changing tongue actuator , arranged to be implanted at least in part helically into a tongue to treat obstructive sleep apnea, wherein the actuator comprises a helical section extending along a helix axis, the helical section of the actuator having compression portions and widening portions alternatingly provided along the helical section of the actuator, the helical section of the actuator being controllable between: a first state in which the helical section of the actuator has a relatively low stiffness to allow unhindered movement of the tongue when implanted; and a second state in which the helical section of the actuator has a higher stiffness than in the first state, and is deformed in such a way that the compression portions have moved away from the helix axis, and the widening portions have moved towards the helix axis. a first state in which the helical section of the actuator has a relatively low stiffness to allow unhindered movement of the tongue when implanted; and a second state in which the helical section of the actuator has a higher stiffness than in the first state, and is deformed in such a way that the compression portions have moved away from the helix axis, and the widening portions have moved towards the helix axis.
A prosthesis for transcatheter correction of cardiovascular abnormalities comprising: a radially expandable mesh body that is configured to self-expand into at least one disc after becoming radially unconstrained, the radially expandable mesh body defining a volume therein when expanded; a tension coil spring disposed within the volume of the mesh, the tension coil spring being attached to a proximal end and distal end of the prosthesis along an axis that defines a central region of the prosthesis , characterized in the tension coil spring being configured to contract into a relaxed state when not being stretched that results in the prosthesis being shortened along the axis and expanded radially. a radially expandable mesh body that is configured to self-expand into at least one disc after becoming radially unconstrained, the radially expandable mesh body defining a volume therein when expanded; a tension coil spring disposed within the volume of the mesh, the tension coil spring being attached to a proximal end and distal end of the prosthesis along an axis that defines a central region of the prosthesis , characterized in the tension coil spring being configured to contract into a relaxed state when not being stretched that results in the prosthesis being shortened along the axis and expanded radially.
A passive partial aerodynamic lift marine propulsion multihull ship (10; 110; 210), intended to transport people and/or goods, having a ratio of a length of the ship to a width of the ship smaller than two, and with which an orthogonal frame of reference XYZ is associated, whereof a longitudinal axis Z, oriented from the back to the front of the ship, corresponds to a roll axis of the ship, a transverse axis Y corresponds to a pitch axis of the ship and an axis X corresponds to a yaw axis of the ship, the ship including a superstructure and two hulls, the superstructure of the ship forming a wing able to passively generate an aerodynamic lift comprised between 20 and 90% of the total weight of the ship at a cruising speed of the ship, said wing including curved ends connected to each of the hulls and having a developed surface of an extrados of the wing substantially equal to the product of the length of the ship multiplied by the width of the ship, characterized in that : - each hull (50, 60 ; 150, 160, 190 ; 250, 260, 290) is of the planing hull type, the hulls defining together at least one hydrodynamic center of lift (H2) behind the center of gravity (G) and at least one hydrodynamic center of lift (H1) in front of the center of gravity (G), and - a point A, of application of the aerodynamic lift generated by the superstructure (12 ; 112 ; 212), is located behind a center of gravity G, of application of the gravitational forces on the ship, a point H, of application of the resultant of the hydrodynamic forces generated by the hulls (50, 60 ; 150, 160, 190 ; 250, 260, 290) being located in front of the center of gravity G. - each hull (50, 60 ; 150, 160, 190 ; 250, 260, 290) is of the planing hull type, the hulls defining together at least one hydrodynamic center of lift (H2) behind the center of gravity (G) and at least one hydrodynamic center of lift (H1) in front of the center of gravity (G), and - a point A, of application of the aerodynamic lift generated by the superstructure (12 ; 112 ; 212), is located behind a center of gravity G, of application of the gravitational forces on the ship, a point H, of application of the resultant of the hydrodynamic forces generated by the hulls (50, 60 ; 150, 160, 190 ; 250, 260, 290) being located in front of the center of gravity G.
A CD40/CD40L inhibitor for use in a method of treating ulcerative colitis in a subject, the method comprising administering to the subject the CD40/CD40L inhibitor in an ingestible device, wherein the ingestible device comprises: an ingestible housing comprising a reservoir having a therapeutically effective amount of the CD40/CD40L inhibitor stored therein; a release mechanism having a closed state which retains the CD40/CD40L inhibitor in the reservoir and an open state which allows for the release of the CD40/CD40L inhibitor from the reservoir to the exterior of the device; an actuator which controls the transition of the release mechanism from the closed to the open state; a detector for detecting the location of the ingestible device in the subject's gastrointestinal tract; and a processor which is coupled to the detector and to the actuator and which triggers the actuator to cause the release mechanism to transition from its closed state to its open state to release the CD40/CD40L inhibitor in the cecum when it is determined that the ingestible device is in the cecum of the subject, wherein the site of disease is in the colon, wherein determining the location of the ingestible device in the gastrointestinal tract comprises detecting a transition of the ingestible device from the ileum to the cecum. wherein the ingestible device comprises: an ingestible housing comprising a reservoir having a therapeutically effective amount of the CD40/CD40L inhibitor stored therein; a release mechanism having a closed state which retains the CD40/CD40L inhibitor in the reservoir and an open state which allows for the release of the CD40/CD40L inhibitor from the reservoir to the exterior of the device; an actuator which controls the transition of the release mechanism from the closed to the open state; a detector for detecting the location of the ingestible device in the subject's gastrointestinal tract; and an ingestible housing comprising a reservoir having a therapeutically effective amount of the CD40/CD40L inhibitor stored therein; a release mechanism having a closed state which retains the CD40/CD40L inhibitor in the reservoir and an open state which allows for the release of the CD40/CD40L inhibitor from the reservoir to the exterior of the device; an actuator which controls the transition of the release mechanism from the closed to the open state; a detector for detecting the location of the ingestible device in the subject's gastrointestinal tract; and a processor which is coupled to the detector and to the actuator and which triggers the actuator to cause the release mechanism to transition from its closed state to its open state to release the CD40/CD40L inhibitor in the cecum when it is determined that the ingestible device is in the cecum of the subject, wherein the site of disease is in the colon,
An electrode structure comprising: a current collector ; an active material layer comprising a main surface and a first end face other than the main surface ; and a separator layer , wherein the separator layer comprises a solid electrolyte and a binder, the active material layer covers a first part of at least one surface of the current collector , the separator layer covers the main surface of the active material layer , at least a part of the first end face and a second part of the at least one surface of the current collector , and the separator layer comprises a first end part which is brought into contact with the second part of the at least one surface of the current collector , and wherein the electrode structure satisfies a ratio b/a falling within a range of 0.0001 to 0.5, where a is a distance from the first end face of the active material layer to the first end part of the separator layer , and b is a distance in a direction parallel to the at least one surface of the current collector , which is from a first edge of the active material layer to a surface of the separator layer , the main surf ace of the active material layer and the first end face of the active material layer intersect at the first edge of the active material layer . a current collector ; an active material layer comprising a main surface and a first end face other than the main surface ; and a separator layer , wherein the separator layer comprises a solid electrolyte and a binder, the active material layer covers a first part of at least one surface of the current collector , the separator layer covers the main surface of the active material layer , at least a part of the first end face and a second part of the at least one surface of the current collector , and the separator layer comprises a first end part which is brought into contact with the second part of the at least one surface of the current collector , and wherein the electrode structure satisfies a ratio b/a falling within a range of 0.0001 to 0.5, where a is a distance from the first end face of the active material layer to the first end part of the separator layer , and b is a distance in a direction parallel to the at least one surface of the current collector , which is from a first edge of the active material layer to a surface of the separator layer , the main surf ace of the active material layer and the first end face of the active material layer intersect at the first edge of the active material layer .
A synapse circuit of a neural network for performing TD-lambda temporal difference learning, the neural network approximating a value function (V(s), Q(s,a)), the synapse circuit comprising: a first resistive memory device ; a second resistive memory device ; and a synapse control circuit configured to update a synaptic weight ( g θ , g θ+ , g θ - ) of the synapse circuit by programming a resistive state of the first resistive memory device based on a programmed conductance of the second resistive memory device which stores an eligibility trace of the synapse circuit, wherein the synapse control circuit is further configured to update the eligibility trace of the synapse circuit by programming a resistive state of the second resistive memory device based on a back-propagated derivative ( ∂V t / ∂θ t ) of an output value ( V t ) of the neural network . a first resistive memory device ; a second resistive memory device ; and a synapse control circuit configured to update a synaptic weight ( g θ , g θ+ , g θ - ) of the synapse circuit by programming a resistive state of the first resistive memory device based on a programmed conductance of the second resistive memory device which stores an eligibility trace of the synapse circuit, wherein the synapse control circuit is further configured to update the eligibility trace of the synapse circuit by programming a resistive state of the second resistive memory device based on a back-propagated derivative ( ∂V t / ∂θ t ) of an output value ( V t ) of the neural network .
A disinfection apparatus, comprising: a germicidal pulsed light source arranged within the disinfection apparatus such that germicidal light generated from the germicidal pulsed light source is projected exterior to the disinfection apparatus; power regulator circuitry for applying a trigger voltage to the germicidal pulsed light source at a set frequency greater than approximately 20 Hz; power supply circuitry; one or more electrical charge storage devices coupled to the power supply circuitry and to the germicidal pulsed light source; pulse duration circuitry coupled between the one or more electrical charge storage devices and the germicidal pulsed light source, wherein the one or more electrical charge storage devices and the pulse duration circuitry are configured to discharge a set amount of stored energy in a set amount of time such that energy flux of ultraviolet light in the wavelength range between 200 nm and 320 nm generated at the germicidal pulsed light source is between approximately 20 J/m 2 and approximately 1000 J/m 2 ; an occupancy sensor for determining presence of an individual in a region extending at least 1.0 meter from the disinfection apparatus; a processor; and program instructions executable by the processor for inhibiting and terminating the generation of light from the germicidal pulsed light source upon the occupancy sensor detecting presence of an individual. a germicidal pulsed light source arranged within the disinfection apparatus such that germicidal light generated from the germicidal pulsed light source is projected exterior to the disinfection apparatus; power regulator circuitry for applying a trigger voltage to the germicidal pulsed light source at a set frequency greater than approximately 20 Hz; power supply circuitry; one or more electrical charge storage devices coupled to the power supply circuitry and to the germicidal pulsed light source; pulse duration circuitry coupled between the one or more electrical charge storage devices and the germicidal pulsed light source, wherein the one or more electrical charge storage devices and the pulse duration circuitry are configured to discharge a set amount of stored energy in a set amount of time such that energy flux of ultraviolet light in the wavelength range between 200 nm and 320 nm generated at the germicidal pulsed light source is between approximately 20 J/m 2 and approximately 1000 J/m 2 ; an occupancy sensor for determining presence of an individual in a region extending at least 1.0 meter from the disinfection apparatus; a processor; and program instructions executable by the processor for inhibiting and terminating the generation of light from the germicidal pulsed light source upon the occupancy sensor detecting presence of an individual.
An apparatus configured to be employed in a UE, User Equipment, comprising a processor configured to: generate a beam failure recovery, BFR, request that indicates a new candidate beam; process a CORESET-BFR, Control Resource Set-BFR, of a set of configured CORESETs, wherein the CORESET-BFR is dedicated to deliver a response to the BFR request; receive a response to the BFR request; generate an ACK, Acknowledgement, for the response to the BFR request; process scheduling information for a first PDSCH, Physical Downlink Shared Channel based on the BFR request, wherein the first PDSCH is scheduled by a first CORESET of the set of configured CORESETs, wherein the first CORESET is different than the CORESET-BFR, wherein the first PDSCH is scheduled after the response to the BFR request is received and before a TCI, Transmission Configuration Information, state is one of reconfigured, reactivated, or re-indicated; determine a spatial assumption for the first PDSCH based on an offset between the ACK and the first PDSCH, wherein when the offset is X or more slots the spatial assumption is based on the new candidate beam and wherein when the offset is less than X slots the spatial assumption for the first PDSCH is based on an original beam associated with the first CORESET; wherein X is one of predefined in a specification or configured via higher layer signaling; and process the first PDSCH based on the determined spatial assumption for the first PDSCH. generate a beam failure recovery, BFR, request that indicates a new candidate beam; process a CORESET-BFR, Control Resource Set-BFR, of a set of configured CORESETs, wherein the CORESET-BFR is dedicated to deliver a response to the BFR request; receive a response to the BFR request; generate an ACK, Acknowledgement, for the response to the BFR request; process scheduling information for a first PDSCH, Physical Downlink Shared Channel based on the BFR request, wherein the first PDSCH is scheduled by a first CORESET of the set of configured CORESETs, wherein the first CORESET is different than the CORESET-BFR, wherein the first PDSCH is scheduled after the response to the BFR request is received and before a TCI, Transmission Configuration Information, state is one of reconfigured, reactivated, or re-indicated; determine a spatial assumption for the first PDSCH based on an offset between the ACK and the first PDSCH, wherein when the offset is X or more slots the spatial assumption is based on the new candidate beam and wherein when the offset is less than X slots the spatial assumption for the first PDSCH is based on an original beam associated with the first CORESET; wherein X is one of predefined in a specification or configured via higher layer signaling; and process the first PDSCH based on the determined spatial assumption for the first PDSCH.
A chimeric protein comprising (i) a Factor VIII (FVIII) polypeptide and (ii) an XTEN wherein the FVIII polypeptide has reduced affinity for von Willebrand Factor (VWF), the FVIII polypeptide lacks amino acids 746-1685 corresponding to the mature FVIII polypeptide (SEQ ID NO: 4); the chimeric protein exhibits an extended half-life as compared to a FVIII polypeptide lacking an XTEN; and the chimeric protein retains procoagulant activity. (i) a Factor VIII (FVIII) polypeptide and (ii) an XTEN the FVIII polypeptide has reduced affinity for von Willebrand Factor (VWF), the FVIII polypeptide lacks amino acids 746-1685 corresponding to the mature FVIII polypeptide (SEQ ID NO: 4); the chimeric protein exhibits an extended half-life as compared to a FVIII polypeptide lacking an XTEN; and the chimeric protein retains procoagulant activity.
An electric propulsion system comprising: a prime mover ; an electric generator which is arranged to be driven by the prime mover to generate electric power; an electric propulsion motor ; and an integrated generator-motor controller arranged to control the supply of said electric power to the electric propulsion motor in response to a control signal ; wherein the integrated generator-motor controller is also arranged to feed-forward to the generator a power demand parameter associated with the control signal so as to control the power output of the generator ; characterised in that the prime mover is arranged to operate at a substantially constant speed; wherein the integrated generator-motor controller is arranged to control an inverter to control the supply of said electric power to the electric propulsion motor and wherein the electric propulsion system further comprises a first switching means arranged to allow the inverter to be selectably connected to the generator or to the propulsion motor . a prime mover ; an electric generator which is arranged to be driven by the prime mover to generate electric power; an electric propulsion motor ; and an integrated generator-motor controller arranged to control the supply of said electric power to the electric propulsion motor in response to a control signal ; wherein the integrated generator-motor controller is also arranged to feed-forward to the generator a power demand parameter associated with the control signal so as to control the power output of the generator ; characterised in that the prime mover is arranged to operate at a substantially constant speed; wherein the integrated generator-motor controller is arranged to control an inverter to control the supply of said electric power to the electric propulsion motor and wherein the electric propulsion system further comprises a first switching means arranged to allow the inverter to be selectably connected to the generator or to the propulsion motor .
A method for producing a component by forming a workpiece from sheet metal using a manufacturing device with two press beams oriented in parallel with one another, with bending tools mounted on the press beams , and with a controller having a manufacturing program for the semi-automatic operation of the manufacturing device , wherein at least two manufacturing steps (F1, F2) are each performed using bend-forming, and wherein one manufacturing step (F1, F2) comprises the measures: - positioning stops for orienting the workpiece in a processing region , wherein the positioning of the stops is carried out automatically by means of the controller based on commands of the manufacturing program ; - placing a workpiece into the processing region by placing it on a lower tool and positioning the workpiece against and/or placing it on the stops by means of an operator; - carrying out the bend-forming operation by pressing an upper tool against the workpiece and the lower tool by means of moving the press beams against each other; - moving the press beams apart; - removing the workpiece from the lower tool by means of the operator; wherein, after a first manufacturing step (F1), the performance of a subsequent, second manufacturing step (F2) of the manufacturing program is started, wherein the processing region is captured by at least one camera , characterized in that the position and orientation of the workpiece is determined by an image recognition program , and, based on the position and orientation of the workpiece determined by the image recognition program , the subsequent, second manufacturing step (F2) is started by the manufacturing program by repositioning the stops . - positioning stops for orienting the workpiece in a processing region , wherein the positioning of the stops is carried out automatically by means of the controller based on commands of the manufacturing program ; - placing a workpiece into the processing region by placing it on a lower tool and positioning the workpiece against and/or placing it on the stops by means of an operator; - carrying out the bend-forming operation by pressing an upper tool against the workpiece and the lower tool by means of moving the press beams against each other; - moving the press beams apart; - removing the workpiece from the lower tool by means of the operator; wherein, after a first manufacturing step (F1), the performance of a subsequent, second manufacturing step (F2) of the manufacturing program is started, wherein the processing region is captured by at least one camera , characterized in that the position and orientation of the workpiece is determined by an image recognition program , and, based on the position and orientation of the workpiece determined by the image recognition program , the subsequent, second manufacturing step (F2) is started by the manufacturing program by repositioning the stops .