mhurhangee/patent-ind-claim-en huggingface dataset:
A reporter composition, comprising: a nucleotide selected from the group consisting of a deoxyribonucleotide, a ribonucleotide, a peptide nucleotide, a morpholino, a locked nucleotide, a glycol nucleotide and a threose nucleotide; a high charge mass moiety comprising moiety a or moiety b; for triggering a detectable change in a sensitive biosensor when the reporter composition is operably coupled to the biosensor; wherein a net charge mass of the high charge mass moiety is positive in turn in an acidic pH and/or a net charge mass of the high charge mass moiety is negative in turn in an alkaline pH; and a linker molecule attached to the nucleotide and the high charge mass moiety, wherein the linker molecule comprises a molecule of the following general formula: R 1 -L-R 2 wherein L comprises a linear chain comprising 1 to 100 alkyl groups, oxy alkyl groups, or combinations thereof, and R 1 and R 2 are functional groups that are identical to or different from each other, each of which is selected from the group consisting of alcohol group, carboxyl group, amine group or amide group; characterised in that the reporter reports on charge mass and not enzymatic activity or fluorescence and the linker attaches to the nucleotide at the phosphate linkage in the nucleotide, or the sugar group or the base group so as to allow for polymerisation by a polymerase or hydrogen bonding between the bases of nucleotides when they hybridise with their compliment base. a nucleotide selected from the group consisting of a deoxyribonucleotide, a ribonucleotide, a peptide nucleotide, a morpholino, a locked nucleotide, a glycol nucleotide and a threose nucleotide; a high charge mass moiety comprising moiety a or moiety b; for triggering a detectable change in a sensitive biosensor when the reporter composition is operably coupled to the biosensor; wherein a net charge mass of the high charge mass moiety is positive in turn in an acidic pH and/or a net charge mass of the high charge mass moiety is negative in turn in an alkaline pH; and a linker molecule attached to the nucleotide and the high charge mass moiety, wherein the linker molecule comprises a molecule of the following general formula: R 1 -L-R 2 wherein L comprises a linear chain comprising 1 to 100 alkyl groups, oxy alkyl groups, or combinations thereof, and R 1 and R 2 are functional groups that are identical to or different from each other, each of which is selected from the group consisting of alcohol group, carboxyl group, amine group or amide group; characterised in that the reporter reports on charge mass and not enzymatic activity or fluorescence and the linker attaches to the nucleotide at the phosphate linkage in the nucleotide, or the sugar group or the base group so as to allow for polymerisation by a polymerase or hydrogen bonding between the bases of nucleotides when they hybridise with their compliment base.
A row unit for a header , comprising: a pair of gatherers being juxtaposed to one another and spaced apart from one another such that a space is formed in between the pair of gatherers for receiving a row of crop material therethrough, and being configured for conveying a crop material, each gatherer including: a chain ; a plurality of plates connected to the chain , characterized in that : the plurality of plates at least partially overlap to define a conveying floor (CF) that has a continuous upper portion (UP) for receiving and transporting a dislodged crop material and an outer periphery (OP) for gathering the crop material. a chain ; a plurality of plates connected to the chain , characterized in that : the plurality of plates at least partially overlap to define a conveying floor (CF) that has a continuous upper portion (UP) for receiving and transporting a dislodged crop material and an outer periphery (OP) for gathering the crop material. the plurality of plates at least partially overlap to define a conveying floor (CF) that has a continuous upper portion (UP) for receiving and transporting a dislodged crop material and an outer periphery (OP) for gathering the crop material.
An inspection device for an auto loading feeder having a tape guide main body , extending along a conveyance direction of a carrier tape , in which a cover tape for closing an accommodation section for accommodating an electronic component therein is affixed to a base tape on which the accommodation section is provided, and a peeling blade , extending in the conveyance direction with an cutting edge thereof directed towards an upstream side in the conveyance direction, which is configured to peel off the cover tape from the base tape of the carrier tape guided by the tape guide main body , the inspection device comprising: a height detection sensor configured to output a signal corresponding to a height position of the peeling blade with respect to a reference point on the tape guide main body ; and a height discrimination section configured to discriminate, based on an output signal of the height detection sensor , whether the height position of the peeling blade stays within a predetermined range with respect to the carrier tape guided by the tape guide main body . a height detection sensor configured to output a signal corresponding to a height position of the peeling blade with respect to a reference point on the tape guide main body ; and a height discrimination section configured to discriminate, based on an output signal of the height detection sensor , whether the height position of the peeling blade stays within a predetermined range with respect to the carrier tape guided by the tape guide main body .
A dispensing apparatus for dispensing pellets from a rotary press, comprising an inlet channel that can be connected to an ejection apparatus of the rotary press for pellets produced in the rotary press as well as a first dispensing channel and a second dispensing channel , further comprising a diverter arranged between the inlet channel on the one hand and the first and second dispensing channel on the other hand, wherein the diverter can be adjusted between a first position, in which pellets are conveyed from the inlet channel into the first dispensing channel , and a second position, in which pellets are conveyed from the inlet channel into the second dispensing channel , characterized in that a permanently open pressure compensation channel via which pressure compensation between the inlet channel on the one hand and the first and/or second dispensing channel on the other hand takes place is provided in parallel with the diverter .
A link configuration method for configuring a link between a first site and a second site, the method comprising: obtaining , by a controller, a first link profile for the first site and a second link profile for the second site from a link profile library, wherein the link profile library comprises a plurality of link profiles; obtaining , by the controller, preconfigured global configuration information, wherein the global configuration information comprises an address pool for configuring a link; generating (204, 305 to 308), by the controller, a first link configuration parameter of the first site and a second link configuration parameter of the second site based on the address pool, the first link profile, and the second link profile and according to a preset link configuration rule; sending , by the controller, the first link configuration parameter to the first site; and sending , by the controller, the second link configuration parameter to the second site; wherein a first access router of the first site serves as a first gateway of the first site to communicate with a second access router of the second site, and wherein the second access router serves as a second gateway of the second site to communicate with the first access router; characterized in that each of the plurality of link profiles comprises a gateway type, a link type, a link name, and a wide area network side physical port number of the corresponding gateway, wherein the gateway type includes a single gateway or dual gateways. obtaining , by a controller, a first link profile for the first site and a second link profile for the second site from a link profile library, wherein the link profile library comprises a plurality of link profiles; obtaining , by the controller, preconfigured global configuration information, wherein the global configuration information comprises an address pool for configuring a link; generating (204, 305 to 308), by the controller, a first link configuration parameter of the first site and a second link configuration parameter of the second site based on the address pool, the first link profile, and the second link profile and according to a preset link configuration rule; sending , by the controller, the first link configuration parameter to the first site; and sending , by the controller, the second link configuration parameter to the second site; wherein a first access router of the first site serves as a first gateway of the first site to communicate with a second access router of the second site, and wherein the second access router serves as a second gateway of the second site to communicate with the first access router; characterized in that each of the plurality of link profiles comprises a gateway type, a link type, a link name, and a wide area network side physical port number of the corresponding gateway, wherein the gateway type includes a single gateway or dual gateways.
Extruder for the viscosity-increasing preparation of meltable polymers, at least comprising a barrel having an inner barrel aperture in which an extruder screw having at least one extruder screw flight (31, ..., 35) in the form of a helical coil is rotatably arranged, which extruder screw is divided in terms of its external diameter into a diameter start region , a diameter middle region and a diameter end region, wherein: - the diameter middle region has a greater external diameter than the rest of the diameter regions; - a respective transition cone zone is formed between diameter regions of different diameter; - at least one degassing zone is formed in the diameter middle region and has a barrel aperture from which at least one suction-removal opening extends to an outer side of the barrel , said suction-removal opening being arranged in an end portion (23.2) at the end of the degassing zone , - characterized in that , in the diameter middle region of the extruder screw , a flow channel which is formed between an extruder screw shaft core and an inner wall of the barrel aperture is in the form of an annular expansion nozzle, wherein the external diameter of the at least one extruder screw flight is constant and the radial height of the flow channel becomes larger. - the diameter middle region has a greater external diameter than the rest of the diameter regions; - a respective transition cone zone is formed between diameter regions of different diameter; - at least one degassing zone is formed in the diameter middle region and has a barrel aperture from which at least one suction-removal opening extends to an outer side of the barrel , said suction-removal opening being arranged in an end portion (23.2) at the end of the degassing zone , - characterized in that , in the diameter middle region of the extruder screw , a flow channel which is formed between an extruder screw shaft core and an inner wall of the barrel aperture is in the form of an annular expansion nozzle, wherein the external diameter of the at least one extruder screw flight is constant and the radial height of the flow channel becomes larger.
An adjustable interface device for connecting two components of a medical device for an occlusion crossing or atherectomy procedure, comprising: an elongate body having a first end (62-1), a second end (62-2), an interior channel (62-4), and a side wall (62-3) that surrounds the interior channel, the interior channel configured to extend between the first end and the second end, the elongate body having a longitudinal axis that longitudinally extends through the interior channel, the side wall configured to define a first connector portion adjacent the second end, the first connector portion having an annular recess (68-2), the first connector portion configured to attach to a respective one of the two components of the medical device; an elongate member having a head end portion (64-1) and a shaft portion (64-2) that longitudinally extends from the head end portion, the shaft portion being located at least partially in the interior channel of the elongate body, the shaft portion configured to slidably move axially along the longitudinal axis to adjust a length of the adjustable interface device, the head end portion defining a second connector portion configured to attach to the other of the two components of the medical device; and an adapter having a threaded end portion (69-2) and a snap-fit end portion (69-3), the snap-fit end portion having an annular protrusion (69-4) configured for engagement with the annular recess of the first connector portion of the elongate body. an elongate body having a first end (62-1), a second end (62-2), an interior channel (62-4), and a side wall (62-3) that surrounds the interior channel, the interior channel configured to extend between the first end and the second end, the elongate body having a longitudinal axis that longitudinally extends through the interior channel, the side wall configured to define a first connector portion adjacent the second end, the first connector portion having an annular recess (68-2), the first connector portion configured to attach to a respective one of the two components of the medical device; an elongate member having a head end portion (64-1) and a shaft portion (64-2) that longitudinally extends from the head end portion, the shaft portion being located at least partially in the interior channel of the elongate body, the shaft portion configured to slidably move axially along the longitudinal axis to adjust a length of the adjustable interface device, the head end portion defining a second connector portion configured to attach to the other of the two components of the medical device; and an adapter having a threaded end portion (69-2) and a snap-fit end portion (69-3), the snap-fit end portion having an annular protrusion (69-4) configured for engagement with the annular recess of the first connector portion of the elongate body.
Slip joint apparatus, said slip joint apparatus including a first component having a first end and a second component having a second end , the second end of the second component arranged such that it can be brought into overlapping engagement with the first end of the first component in use, and an intermediate joining element for helping to join the first and second components together in use, and wherein movement limitation means are provided on or associated with, at or adjacent the first end of the first component for limiting movement of at least part of the intermediate joining element in at least one direction relative to said first component in use, characterised in that the intermediate joining element has a first skirt or platform provided at or adjacent a first end , and a second skirt or platform provided at or adjacent a second end , and an intermediate section provided between the first end, skirt or platform and the second end, skirt or platform, the intermediate section having larger dimensions and/or diameter compared to the second end, skirt or platform, and smaller dimensions and/or diameter compared to the first end, skirt or platform, and wherein the second end, skirt or platform of the intermediate joining element is engageable with or locatable in the movement limitation means provided on the first component in use.
An instrument fixation device for holding a medical instrument in a trocar system , the trocar system comprising a trocar cannula and a trocar housing , the instrument fixation device comprising a trocar housing connector adapted for connection between the instrument fixation device and the trocar housing , the instrument fixation device comprising a first side intended to face the trocar housing during use and a second side being an opposite side to the first side , the instrument fixation device comprising an instrument receiving opening extending in a longitudinal direction (L) of the instrument fixation device between the first and the second side of the instrument fixation device , the instrument fixation device having an open configuration allowing the medical instrument to move freely in the longitudinal direction (L) and a closed configuration wherein the medical instrument is restrained from movement in the longitudinal direction (L) by clamping of the medical instrument between a first and second opposing clamping surface of the instrument fixation device with a clamping force being directed in a transverse direction (T) being perpendicular to the longitudinal direction (L), the instrument fixation device comprising an actuation member configured for shifting the configuration of the instrument fixation device between the open configuration and the closed configuration, by means of a translational movement of the actuation member , the translational movement being in the transverse direction (T) of the instrument fixation device and wherein the closed configuration of the instrument fixation device includes a sub-set of positions with varying distances between the first and the second opposing clamping surface in each of the positions in the sub-set of positions, characterized in that the actuation member comprises a male threaded member and a female threaded member being engaged with each other, and wherein the instrument fixation device is shifted between the open configuration and the closed configuration by rotating the male threaded member relative to the female threaded member and wherein the instrument fixation device comprises a first clamping section and a second clamping section , the first and the second clamping sections being opposing sections forming together the opening , the first clamping section comprising the first opposing clamping surface and the second clamping section comprising the second opposing clamping surface of the instrument fixation device , wherein the male threaded member is connected to the first clamping section and the female threaded member is connected to the second clamping section , wherein the actuation device is configured for gradually moving, continuously or discontinuously, the first and second opposing clamping surface(s) in the transverse direction (T).
A meter electronics for detecting and identifying a change in a conduit of a vibratory meter , the meter electronics comprising: a processing system including a storage system configured to store a central tendency value of a meter verification parameter and a dispersion value of the meter verification parameter, said processing system being configured to: obtain the central tendency value and the dispersion value from the storage system ; and determine a probability based on the central tendency value and the dispersion value to detect if the central tendency value is different than a baseline value, characterized in that the probability comprises a confidence interval of the central tendency value. a processing system including a storage system configured to store a central tendency value of a meter verification parameter and a dispersion value of the meter verification parameter, said processing system being configured to: obtain the central tendency value and the dispersion value from the storage system ; and determine a probability based on the central tendency value and the dispersion value to detect if the central tendency value is different than a baseline value, characterized in that the probability comprises a confidence interval of the central tendency value.
A commutator of a motor comprising a body and hooks forming coil-receiving spaces(S) between the body and inner surfaces of the hooks , wherein the hooks comprise recesses concavely formed on the inner surfaces of the hooks , Characterized in that a ratio of a thickness of the hooks to a depth of the recesses is in the range of 1:0.1 to 1:0.5, and wherein each recess comprises a plurality of serrations which are disposed on an inner surface of the recess .
A primer set for polymerase chain reaction (PCR) for amplification of bacterial DNA, which comprises one primer pair which consists of a combination of a forward primer consisting of a sequence of SEQ ID: No. 43 and a reverse primer consisting of any one sequence of SEQ ID: No. 44, 46 to 48 and 50;
A decoding device , comprising: a unit configured to provide a sequence of information bits comprising context redundancy information within a content of the information bits, wherein the context redundancy information is a bit field in which at least one bit combination is invalid, wherein the sequence of information bits is encoded by a predefined channel code; a trellis generation logic configured to generate a plurality of trellis states based on the sequence of information bits and the channel code; a trellis reduction logic configured to reduce the plurality of trellis states by at least one trellis state based on the context redundancy information; and a decoder configured to decode the sequence of information bits by using a metric based on the reduced trellis states , wherein the context redundancy information comprises cross-context redundancy information, wherein the cross-context redundancy information indicates a correlation between a time division duplex uplink downlink, TDD-ULDL, configuration field and a side link synchronization sub-frame, SLSS, , such that for an SLSS in TDD mode the TDD-ULDL configuration field is restricted to indicate an uplink sub-frame. a unit configured to provide a sequence of information bits comprising context redundancy information within a content of the information bits, wherein the context redundancy information is a bit field in which at least one bit combination is invalid, wherein the sequence of information bits is encoded by a predefined channel code; a trellis generation logic configured to generate a plurality of trellis states based on the sequence of information bits and the channel code; a trellis reduction logic configured to reduce the plurality of trellis states by at least one trellis state based on the context redundancy information; and a decoder configured to decode the sequence of information bits by using a metric based on the reduced trellis states , wherein the context redundancy information comprises cross-context redundancy information, wherein the cross-context redundancy information indicates a correlation between a time division duplex uplink downlink, TDD-ULDL, configuration field and a side link synchronization sub-frame, SLSS, , such that for an SLSS in TDD mode the TDD-ULDL configuration field is restricted to indicate an uplink sub-frame.
A water-insoluble controlled-release pattern recognition receptor agonist ("PRRA") or its pharmaceutically acceptable salt or a pharmaceutical composition comprising such water-insoluble controlled-release PRRA or its pharmaceutically acceptable salt for use in the treatment of cancer, wherein the water-insoluble controlled-release PRRA is administered by intra-tumoral injection, wherein the water-insoluble controlled-release PRRA comprises a plurality of PRRA moieties covalently and reversibly conjugated to a carrier moiety, from which the PRRA moieties are released in aqueous buffer at pH 7.4 and 37°C with a half-life ranging from one day to three months, wherein the PRRA moieties are resiquimod moieties and wherein the carrier moiety is a hydrogel; and wherein the protein level of at least one cytokine selected from the group consisting of IL-6, CCL2 and IL-10 in plasma has a more than 10-fold lower maximum protein level within 24 hours compared to an equivalent molar dose of the corresponding free resiquimod upon intra-tumoral injection.