A Trace Microanalysis Microscope "TMM" comprising: a stationary supporting structure having a surface capable of holding a plurality of trace samples "TSs"; an electronically driven spatial translation platform, coupled to the stationary supporting structure, said platform holding a mechanical mount movable over any point of said surface; a Light Source Module "LSM", a Computer Processing Unit "CPU" ; characterized in that it further comprises, a Multimodal imaging Head "MIH" coupled to and disposed over said mount, said MIH comprising imaging optics means and configured to acquire Multimodal Imaging Data "MID", said MID comprising at least color and multispectral imaging data obtained from target objects contained in said TSs and in a Field-of-View "FoV" of said imaging optics means ; a Light Projection System "LPS" , mounted on a pole disposed over said supporting structure and configured to project light patterns over the surface of said TSs said light patterns characterizing the location of said target objects and their optical parameter values; said CPU is adapted for executing second program instructions for calculating Optical Parameter Maps "OPM" from said MID, wherein said OPM corresponding to the light patterns of the Light Projection System "LPS" ; wherein the Light Source Module "LSM" is coupled to said platform and comprises at least one broad band light source adapted for illuminating at least a portion of a TS in transmission geometry; and wherein the CPU is adapted for executing first program instructions for identifying a location and optical parameter values of the target objects. a stationary supporting structure having a surface capable of holding a plurality of trace samples "TSs"; an electronically driven spatial translation platform, coupled to the stationary supporting structure, said platform holding a mechanical mount movable over any point of said surface; a Light Source Module "LSM", a Computer Processing Unit "CPU" ; characterized in that it further comprises, a Multimodal imaging Head "MIH" coupled to and disposed over said mount, said MIH comprising imaging optics means and configured to acquire Multimodal Imaging Data "MID", said MID comprising at least color and multispectral imaging data obtained from target objects contained in said TSs and in a Field-of-View "FoV" of said imaging optics means ; a Light Projection System "LPS" , mounted on a pole disposed over said supporting structure and configured to project light patterns over the surface of said TSs said light patterns characterizing the location of said target objects and their optical parameter values; said CPU is adapted for executing second program instructions for calculating Optical Parameter Maps "OPM" from said MID, wherein said OPM corresponding to the light patterns of the Light Projection System "LPS" ; wherein the Light Source Module "LSM" is coupled to said platform and comprises at least one broad band light source adapted for illuminating at least a portion of a TS in transmission geometry; and wherein the CPU is adapted for executing first program instructions for identifying a location and optical parameter values of the target objects. <EOS>