mhurhangee/patent-ind-claim-en huggingface dataset:
A fluid transfer device for interconnecting vessels (8; 91; 92; 93), the fluid transfer device comprising: a main body with a first body part providing a first hollow interior merging into a first open end for receiving a fluid obtaining vessel , such as a blood collection tube , and a second body part providing a second hollow interior merging into a second open end for receiving a fluid supplying vessel (91; 92; 93), such as a vial (91; 92; 93), a connection assembly with a double-ended cannula for connecting the first hollow interior with the second hollow interior , and a first encasing member encasing a first cannula part arranged within the first hollow interior , and an actuating member provided inside the first hollow interior , the actuating member being movably arranged along a longitudinal axis of the first body part , wherein the actuating member is in contact with the first encasing member for piercing the first encasing member by the cannula during a movement of the actuating member towards the second body part . a main body with a first body part providing a first hollow interior merging into a first open end for receiving a fluid obtaining vessel , such as a blood collection tube , and a second body part providing a second hollow interior merging into a second open end for receiving a fluid supplying vessel (91; 92; 93), such as a vial (91; 92; 93), a connection assembly with a double-ended cannula for connecting the first hollow interior with the second hollow interior , and a first encasing member encasing a first cannula part arranged within the first hollow interior , and an actuating member provided inside the first hollow interior , the actuating member being movably arranged along a longitudinal axis of the first body part , wherein the actuating member is in contact with the first encasing member for piercing the first encasing member by the cannula during a movement of the actuating member towards the second body part .
A sliding member that configures a mechanical seal comprising sliding faces (S) configured to slide in relation to one another, at least one of the sliding faces (S) being provided with a plurality of dimples (11; 12; 13; 14; 15; 16; 17; 21; 41; 51; 52; 53), wherein the plurality of the dimples (11; 12; 13; 14; 15; 16; 17; 21; 41; 51; 52; 53) each include a bottom portion (11d; 21e; 21f; 21h; 21j; 41d) recessed from the sliding face and have multi-sided shapes whose edges (A1-B1, A1-C1, B1-C1; A2-B2, A2-C2, B2-C2; A3-B3, A3-C3, B3-C3; A4-B4, A4-C4, B4-C4; A5-B5, A5-C5, B5-C5; A6-B6, A6-C6, B6-C6; A7-B7, A7-C7, B7-C7; A8-B8, A8-C8, B8-C8; A9-B9, A9-C9, B9-C9; A10-B10, B10-C10, C10-D10, D10-A10; A11-B11, B11-C11, C11-D11, D11-E11, Ell-All; A12-B12, B12-C12, C12-D12, D12-E12, E12-F12, F12-A12) are uninterruptedly surrounded by the sliding face (S), wherein a pair of the edges (A1-B1, A1-C1; A2-B2, A2-C2; A3-B3, A3-C3; A4-B4, A4-C4; A5-B5, A5-C5; A6-B6, A6-C6; A7-B7, A7-C7; A8-B8, A8-C8; A9-B9, A9-C9; A10-B10, D10-C10; A11-B11, A11-E11; B11-C11, E11-D11; A12-B12, F12-E12; B12-C12, E12-D12) of each of the multi-sided dimples (11; 12; 13; 14; 15; 16; 17; 21; 41; 51; 52; 53), extending radially on opposite sides of a radial axis of the sliding member, are sloped to become farther apart as they extend toward a radially outer side, characterized in that another of the edges, which connects end points on the radially outer side of the pair of the edges, is formed such that its length is not greater than each length of the pair of the edges.
A compound for use in a method of treating an acute myeloid leukemia in a subject, wherein the compound is a mutant isocitrate dehydrogenase 2 (IDH2) inhibitor 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{ [2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol having the following formula: or a pharmaceutically acceptable salt, solvate, tautomer, stereoisomer, isotopologue, or a polymorph thereof (COMPOUND 1), wherein the acute myeloid leukemia is characterized by the presence of a mutant allele of IDH2 and the absence of a mutant allele of NRAS.
A device for fixing accessories on doors or windows, the door or window having a fixed frame and a mobile frame , each equipped with a perimeter channel defined by a pair of parallel wings protruding from a bottom of a profile; the pair of wings being equipped with corresponding end stretches parallel to the bottom of the profile and facing each other to delimit an upper opening ; the fixing device comprising at least one body-plate and a connecting element configured to be rotatably connected to a body of an accessory to be fixed to the channel ; the body-plate being equipped with a rhomboid perimeter profile forming two end heads , configured in the fashion of a cam, for the contact on both sides, with interference, on corresponding inside walls of the pair of wings following a rotation of the body-plate inside the channel and about an axis (Z) which is transversal relative to the bottom of the channel ; the fixing device further comprising a prismatic body , made between the body-plate and the connecting element , and having a rhomboid perimeter profile forming two further cam end heads configured for a contact on both sides, with interference, on corresponding side walls of the end stretches , following the rotation, in such a way as to form a further second point for locking the body of the accessory in the channel characterised in that the body-plate is connected to the prismatic body with a surface which is inclined relative to the axis (Z) of rotation, at least along the portions of the two bodies forming the corresponding end heads ; the inclined surface forming a third locking zone on both sides inside the channel , following the rotation, by the contact with interference of the inclined surface on the vertex formed by the side and lower walls of the end stretches .
An isolated antibody that binds CD30L comprising a CDRH1, a CDRH2 and a CDRH3 and a CDRL1, a CDRL2 and a CDRL3, wherein CDRL1 is the CDRL1 consensus sequence of SEQ ID NO:30, wherein CDRL2 is the CDRL2 consensus sequence of SEQ ID NO:31, wherein CDRL3 is the CDRL3 consensus sequence of SEQ ID NO:32, wherein CDRH1 is the CDRH1 consensus sequence of SEQ ID NO:33, wherein CDRH2 is the CDRH2 consensus sequence of SEQ ID NO:34 and wherein CDRH3 is the CDRH3 consensus sequence of SEQ ID NO:35.
A computing system implemented method for providing selectively extendable and acceptable access tokens to users of a data management system based on access policies, the method comprising: receiving initial access request data from a user requesting access to secured data or services of a data management system, the initial access request data including authentication data from a user of the data management system; verifying that the authentication data is valid; if the authentication data is valid, generating access token data representing an access token for accessing the data management system; providing the access token data to the user; receiving , from the user, subsequent access request data including the access token data; retrieving access policy data corresponding to an access policy associated with the access token data, the access policy defining one or more access policy rules including a lifetime of the access token and conditions for accepting and extending the lifetime of the access token; comparing the subsequent access request data and the access token data to the access policy rules; determining whether the subsequent access request data satisfies the access policy rules; and if the subsequent access request data and the access token data satisfy the policy rules, allowing the user to access the secured data or services and extending the lifetime of the access token by a selected amount of time based on the access policy data. receiving initial access request data from a user requesting access to secured data or services of a data management system, the initial access request data including authentication data from a user of the data management system; verifying that the authentication data is valid; if the authentication data is valid, generating access token data representing an access token for accessing the data management system; providing the access token data to the user; receiving , from the user, subsequent access request data including the access token data; retrieving access policy data corresponding to an access policy associated with the access token data, the access policy defining one or more access policy rules including a lifetime of the access token and conditions for accepting and extending the lifetime of the access token; comparing the subsequent access request data and the access token data to the access policy rules; determining whether the subsequent access request data satisfies the access policy rules; and if the subsequent access request data and the access token data satisfy the policy rules, allowing the user to access the secured data or services and extending the lifetime of the access token by a selected amount of time based on the access policy data.
Engine comprising a propeller unit with a pair of contrarotating propellers , a gas generator supplying a power turbine , the pair of propellers being rotationally driven by the shaft of the power turbine via a speed reduction gearbox , the axis of rotation (XX) of the pair of propellers not being coaxial with that (YY) of the power turbine , the speed reduction gearbox comprising a differential gearset and a first stage comprising a simple gearset connecting the turbine shaft and the differential gearset , the air intake of the engine comprising an air intake duct , the air intake duct being in the shape of a lobe adjacent to the assembly formed by the simple gearset and the differential gearset , wherein the first stage with a simple gearset comprises a first toothed wheel , integral with the turbine shaft , said first toothed wheel meshing with a second toothed wheel of the first stage , said second toothed wheel being mounted so as to rotate about the axis (XX) of the pair of propellers.
A mitral valve prosthesis comprising: a) an expandable inflow region formed of a plurality of cells and configured to expand within and support against the walls of the left atrium, wherein the expandable inflow region has a cross-sectional diameter larger than the annulus of the native mitral valve; b) an expandable outflow region formed of a plurality of cells and configured to expand within and support against the native mitral valve annulus, wherein the expandable outflow region comprises: i) two or more engagement arms ; and ii) at least two anchor attachment points ; and c) a prosthetic valve , wherein each anchor attachment point is attached to a proximal end of one or more anchor , wherein a distal end of each anchor is further attached to an anchoring element , wherein the anchoring element can be adjusted to adjust tension on the anchor , wherein the anchoring element is a clip and includes jaws , wherein the anchoring element comprises a releasable lock , wherein anchors pass across the lock of the anchoring element . a) an expandable inflow region formed of a plurality of cells and configured to expand within and support against the walls of the left atrium, wherein the expandable inflow region has a cross-sectional diameter larger than the annulus of the native mitral valve; b) an expandable outflow region formed of a plurality of cells and configured to expand within and support against the native mitral valve annulus, wherein the expandable outflow region comprises: i) two or more engagement arms ; and ii) at least two anchor attachment points ; and i) two or more engagement arms ; and ii) at least two anchor attachment points ; and c) a prosthetic valve , wherein each anchor attachment point is attached to a proximal end of one or more anchor , wherein a distal end of each anchor is further attached to an anchoring element , wherein the anchoring element can be adjusted to adjust tension on the anchor , wherein the anchoring element is a clip and includes jaws , wherein the anchoring element comprises a releasable lock , wherein anchors pass across the lock of the anchoring element .
A heavy duty tire comprising: a recess portion formed in a buttress portion , the recess portion opening toward a tire outer side and including a floor portion ; a tire diameter-direction air entry and exit promotion portion disposed at one side in a tire diameter direction relative to the floor portion , the tire diameter-direction air entry and exit promotion portion including a slope that, from the floor portion toward a tire surface, gradually decreases in depth from the tire surface, and the tire diameter-direction air entry and exit promotion portion facilitating access of air toward the floor portion ; an air-catching wall portion disposed at an opposite side of the floor portion from the one side at which the tire diameter-direction air entry and exit promotion portion is disposed, an angle of the air-catching wall portion relative to the tire surface being greater than a corresponding angle of the slope ; and a second air entry and exit promotion portion disposed at a different location from the tire diameter-direction air entry and exit promotion portion , the second air entry and exit promotion portion including a slope that, from the floor portion toward the tire surface, gradually decreases in depth from the tire surface, and an angle of the slope of the second air entry and exit promotion portion relative to the tire surface being smaller than a corresponding angle of the air-catching wall portion . a recess portion formed in a buttress portion , the recess portion opening toward a tire outer side and including a floor portion ; a tire diameter-direction air entry and exit promotion portion disposed at one side in a tire diameter direction relative to the floor portion , the tire diameter-direction air entry and exit promotion portion including a slope that, from the floor portion toward a tire surface, gradually decreases in depth from the tire surface, and the tire diameter-direction air entry and exit promotion portion facilitating access of air toward the floor portion ; an air-catching wall portion disposed at an opposite side of the floor portion from the one side at which the tire diameter-direction air entry and exit promotion portion is disposed, an angle of the air-catching wall portion relative to the tire surface being greater than a corresponding angle of the slope ; and a second air entry and exit promotion portion disposed at a different location from the tire diameter-direction air entry and exit promotion portion , the second air entry and exit promotion portion including a slope that, from the floor portion toward the tire surface, gradually decreases in depth from the tire surface, and an angle of the slope of the second air entry and exit promotion portion relative to the tire surface being smaller than a corresponding angle of the air-catching wall portion .
Horological movement comprising: - a running train dedicated to the time division of said horological movement, said running train being driven by a first energy source ; - a regulating member for regulating the running train ; - a chronograph mechanism comprising a chronograph train driven by a second energy source ; - a coupling configured to couple the chronograph train , on demand, to the regulating member to regulate the chronograph train using the regulating member ; - a chronograph start/stop control device cooperating with the coupling ; characterised in that the coupling is a differential coupling comprising: - a first input wheel driven by said running train and having a rotational speed that is regulated by the regulating member ; - an output wheel meshed with said chronograph train ; - a second input wheel , which is an idle wheel, cooperating directly or indirectly with the chronograph start/stop control device ; the coupling comprising a drive assembly configured to rotate the output wheel at said rotational speed regulated by the regulating member , when the rotation of the second input wheel is blocked by the chronograph start/stop control device . - a running train dedicated to the time division of said horological movement, said running train being driven by a first energy source ; - a regulating member for regulating the running train ; - a chronograph mechanism comprising a chronograph train driven by a second energy source ; - a coupling configured to couple the chronograph train , on demand, to the regulating member to regulate the chronograph train using the regulating member ; - a chronograph start/stop control device cooperating with the coupling ; characterised in that the coupling is a differential coupling comprising: - a first input wheel driven by said running train and having a rotational speed that is regulated by the regulating member ; - an output wheel meshed with said chronograph train ; - a second input wheel , which is an idle wheel, cooperating directly or indirectly with the chronograph start/stop control device ; - a first input wheel driven by said running train and having a rotational speed that is regulated by the regulating member ; - an output wheel meshed with said chronograph train ; - a second input wheel , which is an idle wheel, cooperating directly or indirectly with the chronograph start/stop control device ; the coupling comprising a drive assembly configured to rotate the output wheel at said rotational speed regulated by the regulating member , when the rotation of the second input wheel is blocked by the chronograph start/stop control device .
An array antenna system, wherein the array antenna system comprises M antenna radiation units , a strip line feed system , a strip line ground plane , and a strip line cavity , the strip line feed system comprises a phase shift circuit and N first printed circuit boards, PCBs , configured to implement a power allocation function and/or a phase compensation function, M is an integer greater than 1, 1 ≤ N ≤ M, and N is an integer; the phase shift circuit is located in the strip line cavity , P first PCBs are located on an outer surface of the strip line cavity , and P is an integer greater than 1 and less than or equal to N; all or some of the M antenna radiation units are connected to signal planes of the N first PCBs , and the signal planes of the N first PCBs are in a radio frequency connection to the phase shift circuit by using probes ; and ground planes of the N first PCBs are in a radio frequency connection to the strip line ground plane .
An electric machine comprising a cylindrical stator and a frame surrounding the stator , the stator comprising an axial centre line (Z1-Z1), a vertical centre plane (Y1-Y1) passing through the axial centre line (Z1-Z1) and dividing the stator into a left half and a right half, and a horizontal centre plane (X1-X1) passing through the axial centre line (Z1-Z1) and dividing the stator into an upper half (UH) and a lower half (LH), the stator being supported on the frame with support necks (P1, P2, P3, P4) in at least two axially (Z1-Z1) spaced support locations (S1, S2), a first support location (S1) being positioned at a first axial end portion of the stator and a second support location (S2) being positioned at a second axial end portion of the stator , the support necks (P1, P2, P3, P4) in the first support location (S1) and in the second support location (S2) comprising a first group of support necks (P1, P2) and a second group of support necks (P3, P4), the first group of the support necks (P1, P2) comprising at least one upper support neck (P1) positioned in the upper half (UH) of the stator in a first sector (C1) extending 35 degrees on opposite sides of the vertical centre plane (Y1-Y1) and at least one lower support neck (P2) positioned in the lower half (LH) of the stator in a second sector (C2) extending 35 degrees on opposite sides of the vertical centre plane (Y1-Y1), the second group of support necks (P3, P4) comprising a first side support neck (P3) and a second side support neck (P4) being positioned opposite to each other in relation to the vertical centre plane (Y1-Y1), characterized in the first side support neck (P3) being positioned in the left half of the stator at a first angular distance above or below the horizontal centre plane (X1-X1), the second side support neck (P4) being positioned in the right half of the stator at a second angular distance above or below the horizontal centre plane (X1-X1), the first angular distance and the second angular distance being equal and defined by a first angle (α1), which is in degrees within the range α1 = 1.2*90/P and α1 = 0.8*90/P, where P is the number of poles of the electric machine and P > 2.
A syringe assembly comprising: a fluid barrel including a sidewall having an inside surface defining a fluid chamber for retaining fluid and a retaining element; a plunger rod disposed within the fluid chamber comprising a distal end, a proximal end, a plunger rod body extending from the distal end to the proximal end, and a stopper disposed at the distal end of the plunger rod for forming a fluid-tight seal with the inside surface of the fluid barrel; a retraction barrel including a wall having an interior surface defining a needle chamber, an open distal end, a needle cannula attached to a needle hub, the needle cannula being biased to move in a proximal direction; and a trigger element having a distal end, a proximal end , and a trigger element body that extends from the distal end of the trigger element to the proximal end of the trigger element, the trigger element disposed within the retraction barrel being independently moveable from the plunger rod, the trigger element providing a trigger force causing the needle cannula to retract into the retraction barrel; and a snap disposed adjacent to the proximal end of the trigger element, wherein the snap engages the retraction barrel and wherein this engagement hinders movement of the trigger element in the distal direction, characterized in that the proximal end of the plunger rod includes a flat radial ring to deflect the snap so that the trigger element may be moved in the distal direction and retraction of the needle cannula can proceed. a fluid barrel including a sidewall having an inside surface defining a fluid chamber for retaining fluid and a retaining element; a plunger rod disposed within the fluid chamber comprising a distal end, a proximal end, a plunger rod body extending from the distal end to the proximal end, and a stopper disposed at the distal end of the plunger rod for forming a fluid-tight seal with the inside surface of the fluid barrel; a retraction barrel including a wall having an interior surface defining a needle chamber, an open distal end, a needle cannula attached to a needle hub, the needle cannula being biased to move in a proximal direction; and a trigger element having a distal end, a proximal end , and a trigger element body that extends from the distal end of the trigger element to the proximal end of the trigger element, the trigger element disposed within the retraction barrel being independently moveable from the plunger rod, the trigger element providing a trigger force causing the needle cannula to retract into the retraction barrel; and a snap disposed adjacent to the proximal end of the trigger element, wherein the snap engages the retraction barrel and wherein this engagement hinders movement of the trigger element in the distal direction, characterized in that the proximal end of the plunger rod includes a flat radial ring to deflect the snap so that the trigger element may be moved in the distal direction and retraction of the needle cannula can proceed.