mhurhangee/patent-ind-claim-en huggingface dataset:
A can body take-away assembly for a can bodymaker with a vertically oriented, reciprocating, elongated ram assembly and a domer , said ram assembly reciprocating over a generally vertical path and moving between a retracted, lower first position and an extended, upper second position, said ram assembly supporting a can body when in said second position, said take-away assembly comprising: a drive assembly including a motor and a support member ; said take-away assembly motor operatively coupled to said support member and structured to move said drive assembly support member in a generally horizontal direction; a can body transport assembly including a number of gripping assemblies , each gripping assembly coupled to said drive assembly support member ; and said gripping assemblies structured to travel across the path of said ram assembly and to selectively grip a can body ; characterised in that . each gripping assembly includes a number of pairs of opposed, resilient elongated gripping members ; and wherein said pairs of opposed, resilient elongated gripping members are horizontally separated by a distance that is smaller than the horizontal cross-sectional area of can body such that the resilient elongated gripping members flex outwardly to grip a can. a drive assembly including a motor and a support member ; said take-away assembly motor operatively coupled to said support member and structured to move said drive assembly support member in a generally horizontal direction; a can body transport assembly including a number of gripping assemblies , each gripping assembly coupled to said drive assembly support member ; and said gripping assemblies structured to travel across the path of said ram assembly and to selectively grip a can body ; characterised in that . each gripping assembly includes a number of pairs of opposed, resilient elongated gripping members ; and wherein said pairs of opposed, resilient elongated gripping members are horizontally separated by a distance that is smaller than the horizontal cross-sectional area of can body such that the resilient elongated gripping members flex outwardly to grip a can.
An isolated or recombinant peptide comprising a sequence selected from the group comprising SFEWIYKQIFKLWA [SEQ ID NO:1], SFEWIKYQIKKLWA [SEQ ID NO:2], SFEWIYKQIWKLKRGLA [SEQ ID NO:3], formyl-SFKWIYKQIKKLWA [SEQ ID NO:4], SFKWIYKQIKKLWA [SEQ ID NO:5], SFEWIYKQIKKLWAK [SEQ ID NO:6] and SFEWIYKQIKKLWAKKK [SEQ ID NO:7], wherein the isolated or recombinant peptides are bactericidal and/or bacteriostatic.
A method of determining a presence and estimating type, depth, quality and/or volume of a subsurface hydrocarbon accumulation from a hydrocarbon sample related thereto, the method comprising: obtaining sample data associated with a subsurface hydrocarbon accumulation, wherein the sample data comprises a noble gas signature of the sample, a clumped isotope signature of the sample and an ecology signature of the sample, integrating the sample data by using a biogeoinformatic database; identifying one or more relationships between the obtained noble gas signature, the clumped isotope signature and the ecology signature, wherein the identified relationships relate to hydrocarbon accumulation materiality, wherein identifying one or more relationships comprises comparing the noble gas signature, the clumped isotope signature and the ecology signature with a calibration dataset that comprises noble gas signatures, the clumped isotope signatures and the ecology signatures for known subsurface accumulation, and wherein in-situ pressure and/or temperature data is used to calibrate the obtained noble gas signature; the clumped isotope signature and the ecology signature; storing the identified relationships and the sample data in a memory, using the identified relationships to estimate the type, depth, quality and/or volume of the subsurface hydrocarbon accumulation, determining to access hydrocarbons from the hydrocarbon accumulation based on the estimated type, depth, quality and/or volume of the subsurface hydrocarbon accumulation, and producing hydrocarbons based on the determination. obtaining sample data associated with a subsurface hydrocarbon accumulation, wherein the sample data comprises a noble gas signature of the sample, a clumped isotope signature of the sample and an ecology signature of the sample, integrating the sample data by using a biogeoinformatic database; identifying one or more relationships between the obtained noble gas signature, the clumped isotope signature and the ecology signature, wherein the identified relationships relate to hydrocarbon accumulation materiality, wherein identifying one or more relationships comprises comparing the noble gas signature, the clumped isotope signature and the ecology signature with a calibration dataset that comprises noble gas signatures, the clumped isotope signatures and the ecology signatures for known subsurface accumulation, and wherein in-situ pressure and/or temperature data is used to calibrate the obtained noble gas signature; the clumped isotope signature and the ecology signature; storing the identified relationships and the sample data in a memory, using the identified relationships to estimate the type, depth, quality and/or volume of the subsurface hydrocarbon accumulation, determining to access hydrocarbons from the hydrocarbon accumulation based on the estimated type, depth, quality and/or volume of the subsurface hydrocarbon accumulation, and producing hydrocarbons based on the determination.
A recombinant microorganism comprising: (a) a first heterologous nucleic acid molecule comprising a nucleotide sequence encoding a D-2-hydroxyacid dehydrogenase; and (b) at least a second heterologous nucleic acid molecule comprising a sequence encoding a thioesterase; wherein a culture of the recombinant microorganism produces a greater amount of a lipid than is produced by a control culture of a microorganism identical in all respects to the recombinant microorganism that includes the first and second heterologous nucleotide sequences, except that the control microorganism does not include the first heterologous nucleotide sequence encoding a D-2-hydroxyacid dehydrogenase, and wherein the recombinant microorganism has a higher propagation and/or proliferation rate than the control microorganism under conditions in which inorganic carbon is the sole source of carbon for proliferation of the culture and production of the lipid. (a) a first heterologous nucleic acid molecule comprising a nucleotide sequence encoding a D-2-hydroxyacid dehydrogenase; and (b) at least a second heterologous nucleic acid molecule comprising a sequence encoding a thioesterase; wherein a culture of the recombinant microorganism produces a greater amount of a lipid than is produced by a control culture of a microorganism identical in all respects to the recombinant microorganism that includes the first and second heterologous nucleotide sequences, except that the control microorganism does not include the first heterologous nucleotide sequence encoding a D-2-hydroxyacid dehydrogenase, and wherein the recombinant microorganism has a higher propagation and/or proliferation rate than the control microorganism under conditions in which inorganic carbon is the sole source of carbon for proliferation of the culture and production of the lipid.
A vibration damping element for a vibration damping system for a turbine nozzle or blade , comprising: an elongated body ; characterised in that the vibration damping element further comprises: a wire mesh member surrounding the elongated body and having a first outer dimension in an inoperative state and a second, larger outer dimension in an operative state, wherein in the operative state, the wire mesh member frictionally engages with an inner surface of a body opening in the turbine nozzle or blade to damp vibration, and in the inoperative state, the wire mesh member slides freely in the body opening in the turbine nozzle or blade ; and a retention member on the elongated body to fix a first section of the wire mesh member relative to a length of the elongated body in the operative state in the body opening of the turbine nozzle or blade . a wire mesh member surrounding the elongated body and having a first outer dimension in an inoperative state and a second, larger outer dimension in an operative state, wherein in the operative state, the wire mesh member frictionally engages with an inner surface of a body opening in the turbine nozzle or blade to damp vibration, and in the inoperative state, the wire mesh member slides freely in the body opening in the turbine nozzle or blade ; and a retention member on the elongated body to fix a first section of the wire mesh member relative to a length of the elongated body in the operative state in the body opening of the turbine nozzle or blade .
A method for aligning sequence reads to a reference sequence, the method comprising: aligning a first set of sequence reads from an entire population of sequence reads to a reference sequence with a Burrows-Wheeler transform using a first seed length, wherein the first seed length is selected based on an error rate of the sequence reads; masking the first set of sequence reads such that the entire population of sequence reads comprises a subset of masked sequence reads and unmasked sequence reads; aligning a second set of sequence reads from the unmasked sequence reads to the reference sequence with the Burrow-Wheeler transform using a second seed length, wherein the second seed length is smaller than the first seed length; determining an alignment of the sequence reads to the reference sequence based on the first set of sequence reads and the second set of sequence reads; and wherein the method further comprises: iteratively masking and aligning additional sets of sequence reads with each subsequent set of reads having a smaller seed length, and determining the alignment of the sequence reads with the additional sets of sequence reads. aligning a first set of sequence reads from an entire population of sequence reads to a reference sequence with a Burrows-Wheeler transform using a first seed length, wherein the first seed length is selected based on an error rate of the sequence reads; masking the first set of sequence reads such that the entire population of sequence reads comprises a subset of masked sequence reads and unmasked sequence reads; aligning a second set of sequence reads from the unmasked sequence reads to the reference sequence with the Burrow-Wheeler transform using a second seed length, wherein the second seed length is smaller than the first seed length; determining an alignment of the sequence reads to the reference sequence based on the first set of sequence reads and the second set of sequence reads; and wherein the method further comprises: iteratively masking and aligning additional sets of sequence reads with each subsequent set of reads having a smaller seed length, and determining the alignment of the sequence reads with the additional sets of sequence reads.
A compound represented by a formula: or a pharmaceutically acceptable salt thereof; wherein is wherein the ring N atom is attached to Ring B; (Ring A) is an optionally substituted pyridin-di-yl, which is substituted with 0, 1, 2, or 3 substituents and each substituent is independently R A , F, Cl, Br, I, CN, -OR A , CF 3 , -NO 2 , -NR A R B , -COR A , -CO 2 R A , -OCOR A , -OCONR A R B , -NR A COR B , or-CONR A R B ; (Ring B) is an optionally substituted pyrazolo[1,5-a]pyrimidin-3,5-di-yl, which is substituted with 0, 1, 2, or 3 substituents and each substituent is independently R A , F, Cl, Br, I, CN, -OR A , CF 3 , -NO 2 , -NR A R B , -COR A , -CO 2 R A , -OCOR A , -OCONR A R B , -NR A COR B , or -CONR A R B ; L is -C(O)NR A , wherein the carbon atom is attached to Ring B E is C 1-3 alkylene having, as chemically appropriate, 0, 1, 2, 3, 4, 5, or 6 substituents, wherein the substituents of E are independently F, Cl, Br, I, OH, =O, C 1-6 alkyl or C 1-6 cycloalkyl, wherein two of the substituents of E may connect together with the attached carbon atom of E to form a 3-membered saturated ring; W is a covalent bond, O, NR A , CR A1 R B1 , CR A1 =CR B1 , or C=CR A1 R B1 ; R A1 and R B1 are independently H, F, Cl, Br, I, or C 1-6 hydrocarbyl; and R A and R B are independently H or C 1-6 hydrocarbyl; R 1a and R 2a are independently H, OH, C 1-3 alkyl, F, Cl, or Br; and R represents 0, 1, 2, 3, 4, or 5 substituents at any ring carbon atom of the pyrrolidine ring and each R is independently H, OH, C 1-3 alkyl, F, Cl, or Br. (Ring A) is an optionally substituted pyridin-di-yl, which is substituted with 0, 1, 2, or 3 substituents and each substituent is independently R A , F, Cl, Br, I, CN, -OR A , CF 3 , -NO 2 , -NR A R B , -COR A , -CO 2 R A , -OCOR A , -OCONR A R B , -NR A COR B , or-CONR A R B ; (Ring B) is an optionally substituted pyrazolo[1,5-a]pyrimidin-3,5-di-yl, which is substituted with 0, 1, 2, or 3 substituents and each substituent is independently R A , F, Cl, Br, I, CN, -OR A , CF 3 , -NO 2 , -NR A R B , -COR A , -CO 2 R A , -OCOR A , -OCONR A R B , -NR A COR B , or -CONR A R B ; L is -C(O)NR A , wherein the carbon atom is attached to Ring B E is C 1-3 alkylene having, as chemically appropriate, 0, 1, 2, 3, 4, 5, or 6 substituents, wherein the substituents of E are independently F, Cl, Br, I, OH, =O, C 1-6 alkyl or C 1-6 cycloalkyl, wherein two of the substituents of E may connect together with the attached carbon atom of E to form a 3-membered saturated ring; W is a covalent bond, O, NR A , CR A1 R B1 , CR A1 =CR B1 , or C=CR A1 R B1 ; R A1 and R B1 are independently H, F, Cl, Br, I, or C 1-6 hydrocarbyl; and R A and R B are independently H or C 1-6 hydrocarbyl; R 1a and R 2a are independently H, OH, C 1-3 alkyl, F, Cl, or Br; and R represents 0, 1, 2, 3, 4, or 5 substituents at any ring carbon atom of the pyrrolidine ring and each R is independently H, OH, C 1-3 alkyl, F, Cl, or Br.
A valved trocar cannula comprising: a cannula sized and shaped to be inserted into an eye, the cannula comprising a distal end configured to be positioned within the eye when in use and a proximal end configured to be positioned outside the eye when in use; and an elastomeric membrane comprising: a first surface at a proximal end of the elastomeric membrane; a second surface at a distal end of the elastomeric membrane; a thickness extending from the first surface to the second surface; and at least one slit extending through the elastomeric membrane, the slit forming a serpentine shape whereby a slope of the slit varies along all or a portion of the slit, said slope forming an oblique angle relative to the first surface and second surface of the elastomeric membrane, the slit having a length extending along the first surface and the second surface of the elastomeric membrane and arranged to permit the passage of a surgical instrument through the elastomeric membrane and into the cannula, the elastomeric membrane disposed at the proximal end of the cannula and connected to the cannula and restricting a free flow of fluid from within the cannula to outside the proximal end of the cannula. a cannula sized and shaped to be inserted into an eye, the cannula comprising a distal end configured to be positioned within the eye when in use and a proximal end configured to be positioned outside the eye when in use; and an elastomeric membrane comprising: a first surface at a proximal end of the elastomeric membrane; a second surface at a distal end of the elastomeric membrane; a thickness extending from the first surface to the second surface; and a first surface at a proximal end of the elastomeric membrane; a second surface at a distal end of the elastomeric membrane; a thickness extending from the first surface to the second surface; and at least one slit extending through the elastomeric membrane, the slit forming a serpentine shape whereby a slope of the slit varies along all or a portion of the slit, said slope forming an oblique angle relative to the first surface and second surface of the elastomeric membrane, the slit having a length extending along the first surface and the second surface of the elastomeric membrane and arranged to permit the passage of a surgical instrument through the elastomeric membrane and into the cannula, the elastomeric membrane disposed at the proximal end of the cannula and connected to the cannula and restricting a free flow of fluid from within the cannula to outside the proximal end of the cannula.
A multi-clutch device for a hybrid module for coupling an internal combustion engine, comprising a disconnect clutch , by means of which torque can be transmitted from the internal combustion engine to the multi-clutch device and by means of which the multi-clutch device can be disconnected from the internal combustion engine; a dual-clutch device , by means of which torque can be transmitted from an electric machine and/or from the disconnect clutch to a drive train, having a first partial clutch and a second partial clutch , wherein the clutches are coupled to one another in a non-rotatable manner via a common rotating part as well as a transmission element for forming a transmission between the electric machine and the multi-clutch device for the purpose of transmitting a rotational movement between the electric machine and the multi-clutch device , characterised in that the common rotating part is rotatably mounted in the axial and/or radial direction by means of a first rotary bearing and the transmission element is rotatably mounted in the axial and/or radial direction by means of a second rotary bearing , wherein the multi-clutch device further comprises a clamping device by means of which the common rotating part as well as the transmission element and consequently also the first rotary bearing and the second rotary bearing can be clamped against one another in the axial direction.
A location-measuring system , comprising: a medical probe comprising a plurality of electrodes; electrodes ; at least three electrode pads configured to define a circuit between the each of the plurality of electrodes for measurement of impedance from each circuit; a display; display ; a memory; and a processor operatively coupled to the memory, medical probe and display, the processor configured to: receive one or more impedance values from the plurality of electrodes in contact with a tissue of an organ; locate each of the plurality of electrodes within the organ based on triangulation by impedance measurements; select at least three electrodes of the plurality of electrodes such that the at least three electrodes have impedance values indicative of sufficient tissue contact with the organ; define a plane between the at least three electrodes; determine a centroid of the plane based at least in part on the locations of the at least three electrodes in the organ; and display, on the display, a visual representation of the at least three electrodes connected by the plane and the centroid of the plane with respect to an anatomical representation of the organ. a medical probe comprising a plurality of electrodes; electrodes ; at least three electrode pads configured to define a circuit between the each of the plurality of electrodes for measurement of impedance from each circuit; a display; display ; a memory; and a processor operatively coupled to the memory, medical probe and display, the processor configured to: receive one or more impedance values from the plurality of electrodes in contact with a tissue of an organ; locate each of the plurality of electrodes within the organ based on triangulation by impedance measurements; select at least three electrodes of the plurality of electrodes such that the at least three electrodes have impedance values indicative of sufficient tissue contact with the organ; define a plane between the at least three electrodes; determine a centroid of the plane based at least in part on the locations of the at least three electrodes in the organ; and display, on the display, a visual representation of the at least three electrodes connected by the plane and the centroid of the plane with respect to an anatomical representation of the organ. receive one or more impedance values from the plurality of electrodes in contact with a tissue of an organ; locate each of the plurality of electrodes within the organ based on triangulation by impedance measurements; select at least three electrodes of the plurality of electrodes such that the at least three electrodes have impedance values indicative of sufficient tissue contact with the organ; define a plane between the at least three electrodes; determine a centroid of the plane based at least in part on the locations of the at least three electrodes in the organ; and display, on the display, a visual representation of the at least three electrodes connected by the plane and the centroid of the plane with respect to an anatomical representation of the organ.
A method for characterizing the spectral phase of laser pulses, the method comprising: (') generating two replicas of each pulse to be characterized; (ii) applying predetermined nonlinear spectral phase shifts to the two replicas; (iii) optically combining the two signals of the preceding step; (iv) applying a nonlinear optical process to the combined signal of the preceding step; (v) measuring the amplitude spectrum of the resulting signal of the preceding step; (vi) performing steps (ii), (iii), (iv) and (v) with different predetermined non-linear spectral phase shifts so as to scan a dispersion range as well as a time delay range between the two replicas and to thereby generate a set of measured amplitude spectra, each spectrum corresponding to a respective predetermined non-linear spectral phase shift; determining the spectral phase of the pulse to be characterized, using the linear spectrum of the pulse to be characterised and a numerical iterative algorithm for iteratively approximating the spectral phase of the pulse to be characterized, whereby the iterative algorithm uses the approximated spectral phase to provide a set of simulated amplitude spectra, each corresponding to one of the respective applied predetermined nonlinear spectral phase shifts, whereby the simulated amplitude spectra are fitted to the measured amplitude spectra; wherein the nonlinear optical process comprises a nonlinear effect that affects the fundamental spectrum of the pulse, in particular second-harmonic generation, sum-frequency generation, difference-frequency generation, the optical Kerr effect, third-harmonic generation, or combinations thereof. (') generating two replicas of each pulse to be characterized; (ii) applying predetermined nonlinear spectral phase shifts to the two replicas; (iii) optically combining the two signals of the preceding step; (iv) applying a nonlinear optical process to the combined signal of the preceding step; (v) measuring the amplitude spectrum of the resulting signal of the preceding step; (vi) performing steps (ii), (iii), (iv) and (v) with different predetermined non-linear spectral phase shifts so as to scan a dispersion range as well as a time delay range between the two replicas and to thereby generate a set of measured amplitude spectra, each spectrum corresponding to a respective predetermined non-linear spectral phase shift; a numerical iterative algorithm for iteratively approximating the spectral phase of the pulse to be characterized, whereby the iterative algorithm uses the approximated spectral phase to provide a set of simulated amplitude spectra, each corresponding to one of the respective applied predetermined nonlinear spectral phase shifts, whereby the simulated amplitude spectra are fitted to the measured amplitude spectra; wherein the nonlinear optical process comprises a nonlinear effect that affects the fundamental spectrum of the pulse, in particular second-harmonic generation, sum-frequency generation, difference-frequency generation, the optical Kerr effect, third-harmonic generation, or combinations thereof.