mhurhangee/patent-ind-claim-en huggingface dataset:
An agent comprising hyaluronic acid or a pharmaceutically acceptable salt thereof having an aminoalkyl cinnamate covalently bonded thereto for use in improving ocular subjective symptoms in a human, wherein the human is a person with dry eye, wherein the ocular subjective symptoms are at least one selected from the group consisting of ocular discomfort, dryness, and grittiness, and wherein the agent is in the form of a solution and the hyaluronic acid or pharmaceutically acceptable salt thereof having an aminoalkyl cinnamate covalently bonded thereto is contained in the solution at a concentration of 0.3% (w/v).
A drive system for a vehicle driveable by muscle force, in particular a skateboard, with at least one axle and at least one wheel , having an electric motor , wherein the electric motor comprises a stator connectable to the axle and a rotor rotatable around the stator , and the wheel comprises a roller which forms a running surface , characterized in that the roller is replaceably connected to the rotor and the rotor comprises a bushing with a front plate , wherein the rotor is connected to a retaining plate non-rotatably coupled to the front plate and the roller is fixed along a longitudinal axis.
A carrier system for carrying a plate-like object (W) to a holding member provided with an object mounting surface on an upper surface, the system comprising: the holding member; a support section provided at the holding member; a vertically-movable suction unit having a plurality of suction members able to suction a plurality of places including at least an area at an outer circumference section of a surface of the object, the carrier system being configured to carry the suction unit to above the holding member located at a predetermined carry-in position, the suction members each being configured to generate a suction force to suction a surface of the object from above in a non-contact manner, the support section being vertically movable and configured to support from below a part of the center section area at another surface of the object; and a driving device configured to drive the suction unit and the support section downward so that the other surface of the object moves toward the object mounting surface of the holding member, in a state where a suction state by the suction unit and a support state by the support section with respect to the object is maintained. the holding member; a support section provided at the holding member; a vertically-movable suction unit having a plurality of suction members able to suction a plurality of places including at least an area at an outer circumference section of a surface of the object, the carrier system being configured to carry the suction unit to above the holding member located at a predetermined carry-in position, the suction members each being configured to generate a suction force to suction a surface of the object from above in a non-contact manner, the support section being vertically movable and configured to support from below a part of the center section area at another surface of the object; and a driving device configured to drive the suction unit and the support section downward so that the other surface of the object moves toward the object mounting surface of the holding member, in a state where a suction state by the suction unit and a support state by the support section with respect to the object is maintained.
A method for activating Coagulation Factor X (FX) comprising; a) contacting an aqueous solution comprising FX with an anion-exchange material under binding conditions for a contact period of at least 5 hours; and b) eluting the activated FX (FXa) from the anion-exchange material with an elution buffer, optionally wherein the FX in the aqueous solution is a FX isolated from mammalian plasma or tissue culture cell supernatant. a) contacting an aqueous solution comprising FX with an anion-exchange material under binding conditions for a contact period of at least 5 hours; and b) eluting the activated FX (FXa) from the anion-exchange material with an elution buffer,
A valve sealing arrangement, comprising: a valve body , and a closing member comprising a closing member contact surface , and a seat , having a center axis , and provided with a sealing portion with a first sealing surface for making contact with the closing member and a back sealing portion with a second sealing surface for making contact with a surface of the valve body , wherein the seat is further provided with a bellows between the first sealing surface and the second sealing surface wherein the bellows comprises bellow members wherein adjacent bellow walls form either inwardly open fold or outwardly open fold , and one or more of the bellow members extends in a direction that is oblique to the center axis of said seat characterized in that the seat is provided with several bent bellow members having an arrow-like formation to form a tree-like bellows structure, wherein the bent bellow members comprise two folds, or fold sections, which extend in different directions, said directions being substantially perpendicular to each other. a valve body , and a closing member comprising a closing member contact surface , and a seat , having a center axis , and provided with a sealing portion with a first sealing surface for making contact with the closing member and a back sealing portion with a second sealing surface for making contact with a surface of the valve body , wherein the seat is further provided with a bellows between the first sealing surface and the second sealing surface wherein the bellows comprises bellow members wherein adjacent bellow walls form either inwardly open fold or outwardly open fold , and one or more of the bellow members extends in a direction that is oblique to the center axis of said seat characterized in that the seat is provided with several bent bellow members having an arrow-like formation to form a tree-like bellows structure, wherein the bent bellow members comprise two folds, or fold sections, which extend in different directions, said directions being substantially perpendicular to each other.
A method for tuning the production level and composition of carotenoids in a fungal host comprising: (a) genetically manipulating one or more polynucleotides in carotenoid biosynthesis in a fungal host, wherein the one or more polynucleotides are selected from (i) the polynucleotides set forth in SEQ ID NOs:1, 3, 5, 7, 8, 10, 11, 13, 14, 16, 17, 19 and 20 or a homologous sequence sharing at least 75% identity thereto or (ii) one or more polynucleotides encoding one or more polypeptides set forth in SEQ ID NOs:2, 4, 6, 12, 15, 18 and 21 or a homologous sequence sharing at least 75% identity thereto, and wherein the fungal host is Rhodospordium or Rhodotorula , and (b) growing the fungal host to produce carotenoids, wherein the carotenoids are selected from the group consisting of lycopene, beta-carotene, gamma-carotene, torulene and torularhodin or derivatives thereof, whereby the production level or composition of the carotenoids is tuned. (a) genetically manipulating one or more polynucleotides in carotenoid biosynthesis in a fungal host, wherein the one or more polynucleotides are selected from (i) the polynucleotides set forth in SEQ ID NOs:1, 3, 5, 7, 8, 10, 11, 13, 14, 16, 17, 19 and 20 or a homologous sequence sharing at least 75% identity thereto or (ii) one or more polynucleotides encoding one or more polypeptides set forth in SEQ ID NOs:2, 4, 6, 12, 15, 18 and 21 or a homologous sequence sharing at least 75% identity thereto, and wherein the fungal host is Rhodospordium or Rhodotorula , and (b) growing the fungal host to produce carotenoids, wherein the carotenoids are selected from the group consisting of lycopene, beta-carotene, gamma-carotene, torulene and torularhodin or derivatives thereof,
An apparatus for treating urinary incontinence comprising: a plurality of interconnected pieces of tubing , each piece of tubing comprising a proximal section, a midsection and a distal section; a device for interconnecting the plurality of pieces of tubing together; and a cover enclosing the pieces of tubing and the device for interconnecting; wherein the proximal and distal sections of each piece of tubing radiate outwards from the midsection of the piece of tubing ; wherein the device for interconnecting comprises an anchor base and a support base , the anchor base and the support base configured to engage and retain each piece of tubing at the proximal section and the midsection, respectively; and the apparatus further comprises an expansion mechanism configured to engage and retain each piece of tubing at the distal section. a plurality of interconnected pieces of tubing , each piece of tubing comprising a proximal section, a midsection and a distal section; a device for interconnecting the plurality of pieces of tubing together; and a cover enclosing the pieces of tubing and the device for interconnecting; wherein the proximal and distal sections of each piece of tubing radiate outwards from the midsection of the piece of tubing ; wherein the device for interconnecting comprises an anchor base and a support base , the anchor base and the support base configured to engage and retain each piece of tubing at the proximal section and the midsection, respectively; and the apparatus further comprises an expansion mechanism configured to engage and retain each piece of tubing at the distal section.
A resin sheet formed from a thermoplastic resin, comprising: a core layer , the core layer being a foam resin layer; and a skin layer located outward of the core layer as determined along a thickness direction, the core layer and the skin layer forming a continuity, wherein the core layer includes a first region (A1) and a second region (A2) located between the first region (A1) and the skin layer , the second region (A2) has a lower average porosity than the first region (A1), said average porosity being lower than 50 %, the average porosity of the second region (A2) decreases going from a center of the core layer as determined along the thickness direction toward a surface of the resin sheet , the thermoplastic resin has a deflection temperature under load not lower than 90 °C, the resin sheet has a thickness of 1 to 40 mm, and the skin layer has a thickness of 5 to 50 % of the thickness of the resin sheet , characterized in that the average porosity of the resin sheet gradually decreases going from a center of the core layer as determined along the thickness direction toward a surface of the resin sheet . a core layer , the core layer being a foam resin layer; and a skin layer located outward of the core layer as determined along a thickness direction, the core layer and the skin layer forming a continuity, wherein the core layer includes a first region (A1) and a second region (A2) located between the first region (A1) and the skin layer , the second region (A2) has a lower average porosity than the first region (A1), said average porosity being lower than 50 %, the average porosity of the second region (A2) decreases going from a center of the core layer as determined along the thickness direction toward a surface of the resin sheet , the thermoplastic resin has a deflection temperature under load not lower than 90 °C, the resin sheet has a thickness of 1 to 40 mm, and the skin layer has a thickness of 5 to 50 % of the thickness of the resin sheet , characterized in that the average porosity of the resin sheet gradually decreases going from a center of the core layer as determined along the thickness direction toward a surface of the resin sheet .
A kit for modular spine stabilization, comprising: an implantable modular spine stabilization system comprising: one or more flexible couplers for dynamic stabilization of a spinal segment of a patient's spine, each flexible coupler having a flexible main body at a first end and a stem extending therefrom and terminating at a second end; one or more rigid rods for rigid stabilization of a spinal segment of the patient's spine, each rigid rod having an elongated shaft ; and one or more bone fasteners for attaching the one or more flexible couplers or rigid rods to the patient's spine; and an instrument set for use with the implantable modular spine stabilization system , characterized in that the instrument set includes a bending instrument for bending a stem of one of the flexible couplers , the bending instrument comprising a base , a pivoting arm , and a pivoting rod holder , the pivoting arm having a pusher head extending from a lower surface of the pivoting arm , and the pivoting rod holder further having a portal for receiving the stem of the one or more flexible couplers , wherein the bending instrument has an open position and a fully closed position in which the stem of the flexible coupler is bent, the pivoting rod holder swiveling upward when the bending instrument is moved to the open position. an implantable modular spine stabilization system comprising: one or more flexible couplers for dynamic stabilization of a spinal segment of a patient's spine, each flexible coupler having a flexible main body at a first end and a stem extending therefrom and terminating at a second end; one or more rigid rods for rigid stabilization of a spinal segment of the patient's spine, each rigid rod having an elongated shaft ; and one or more bone fasteners for attaching the one or more flexible couplers or rigid rods to the patient's spine; and one or more flexible couplers for dynamic stabilization of a spinal segment of a patient's spine, each flexible coupler having a flexible main body at a first end and a stem extending therefrom and terminating at a second end; one or more rigid rods for rigid stabilization of a spinal segment of the patient's spine, each rigid rod having an elongated shaft ; and one or more bone fasteners for attaching the one or more flexible couplers or rigid rods to the patient's spine; and an instrument set for use with the implantable modular spine stabilization system , characterized in that the instrument set includes a bending instrument for bending a stem of one of the flexible couplers , the bending instrument comprising a base , a pivoting arm , and a pivoting rod holder , the pivoting arm having a pusher head extending from a lower surface of the pivoting arm , and the pivoting rod holder further having a portal for receiving the stem of the one or more flexible couplers , wherein the bending instrument has an open position and a fully closed position in which the stem of the flexible coupler is bent, the pivoting rod holder swiveling upward when the bending instrument is moved to the open position.
A method for adaptively storing distance information for volume rendering a first volumetric dataset, the first volumetric dataset including voxels having respective values, the method comprising: generating, by a processor, a second volumetric dataset, the second volumetric dataset identifying a first subset of the voxels of the first volumetric dataset representing empty space and a second subset of the voxels of the first volumetric dataset representing non-empty space; generating, by the processor, a distance field based on the second volumetric dataset, the distance field identifying, for each voxel of the first subset of voxels, a distance to a closest voxel of the second subset of voxels; identifying, by the processor, a third volumetric dataset, the third volumetric dataset identifying, for each of the voxels, to which portion or portions of the first volumetric dataset the respective voxel belongs; selecting, by the processor, at least one compression method based on available storage or an available value range within the third volumetric dataset; characterized by compressing, by the processor, the distance field based on the at least one compression method; and merging, by the processor, the compressed distance field with the third volumetric dataset. generating, by a processor, a second volumetric dataset, the second volumetric dataset identifying a first subset of the voxels of the first volumetric dataset representing empty space and a second subset of the voxels of the first volumetric dataset representing non-empty space; generating, by the processor, a distance field based on the second volumetric dataset, the distance field identifying, for each voxel of the first subset of voxels, a distance to a closest voxel of the second subset of voxels; identifying, by the processor, a third volumetric dataset, the third volumetric dataset identifying, for each of the voxels, to which portion or portions of the first volumetric dataset the respective voxel belongs; selecting, by the processor, at least one compression method based on available storage or an available value range within the third volumetric dataset; characterized by compressing, by the processor, the distance field based on the at least one compression method; and merging, by the processor, the compressed distance field with the third volumetric dataset.
Thrust nozzle system for a satellite intended to be stabilized in autorotation over a geostationary orbit, the said satellite comprising three reference axes X, Y and Z, the Y axis representing the north/south axis and the Z axis corresponding to a pointing direction towards Earth, comprising a first set of thrust nozzles configured for maintaining the satellite in station, the first set comprising an even number of thrust nozzles using electrical propulsion, with a pre-adjusted orientation, the said even number being equal to at least 4, the said first set of thrust nozzles comprising a pair of thrust nozzles on either side of the XZ plane, characterized in that the said thrust nozzles are oriented along three spatial components, both thrust nozzles of each pair having X components of different signs and Y components of the same sign, two thrust nozzles belonging to two different pairs having Y components of different sign.
A heavy truck tire tread having a longitudinal direction, a lateral direction and a thickness direction, said tread having a ground-engaging contact surface (CS) and having a main longitudinal center groove , two main longitudinal shoulder grooves and two main longitudinal intermediate grooves , said five main longitudinal grooves defining six main longitudinal ribs , said five main longitudinal grooves comprising two open grooves and two partially hidden grooves; wherein each of said two partially hidden grooves comprises openings to the ground-engaging contact surface (CS) and undersurface channels connecting adjacent openings , longitudinal sipes extending substantially along the longitudinal direction and connecting successive openings to the respective channel ; characterized in that the longitudinal sipes extend from bottoms of the openings into the tread in the thickness direction away from the ground-engaging contact surface (CS); and said five main longitudinal grooves further comprise one hidden groove, wherein said hidden groove comprises an undersurface duct , a longitudinal sipe extending substantially along the longitudinal direction and connecting said undersurface duct to the ground-engaging contact surface, said hidden groove being a groove where the undersurface duct is running under the ground-engaging contact surface (CS) and will only appear at a later stage in the wear life of the tread , said hidden groove being the main longitudinal center groove of the tread, wherein the longitudinal sipe of said hidden groove extends from the undersurface duct in the thickness direction to the ground-engaging contact surface (CS). wherein each of said two partially hidden grooves comprises openings to the ground-engaging contact surface (CS) and undersurface channels connecting adjacent openings , longitudinal sipes extending substantially along the longitudinal direction and connecting successive openings to the respective channel ; characterized in that the longitudinal sipes extend from bottoms of the openings into the tread in the thickness direction away from the ground-engaging contact surface (CS); and said five main longitudinal grooves further comprise one hidden groove, wherein said hidden groove comprises an undersurface duct , a longitudinal sipe extending substantially along the longitudinal direction and connecting said undersurface duct to the ground-engaging contact surface, said hidden groove being a groove where the undersurface duct is running under the ground-engaging contact surface (CS) and will only appear at a later stage in the wear life of the tread , said hidden groove being the main longitudinal center groove of the tread, wherein the longitudinal sipe of said hidden groove extends from the undersurface duct in the thickness direction to the ground-engaging contact surface (CS).
Batchwise process for aftertreatment of polyol esters prepared by reacting polyols of the general formula (II) H-(-O-[-CR 1 R 2 -] m -) o -OH (II) in which R 1 and R 2 are each independently hydrogen, an alkyl radical having 1 to 5 carbon atoms, preferably methyl, ethyl or propyl, or a hydroxyalkyl radical having 1 to 5 carbon atoms, preferably the hydroxymethyl radical, m is an integer from 1 to 10, preferably 1 to 8 and especially 1, 2, 3 or 4, o is an integer from 2 to 15, preferably 2 to 8 and especially 2, 3, 4 or 5, with excess linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms that have a lower boiling point than the polyols used, in the presence of a Lewis acid selected from the group of titanium, zirconium, hafnium, iron, zinc, boron, aluminum and tin as elements or in the form of compounds thereof as catalyst and in the presence of an adsorbent for sparingly soluble catalyst conversion products in an amount of 0.1 to 5, preferably 0.5 to 1.5, parts by weight per 100 parts by weight of a reaction mixture, while removing the water formed, characterized in that the excess monocarboxylic acid is removed by distillation and water is added to the crude ester obtained, at a temperature below the boiling point of water at the particular pressure and the crude ester with added water is aftertreated with avoidance of basic compounds, and the sparingly soluble conversion products and the adsorbent present in the esterification reaction are filtered off.
A foldable saw including at least a saw handle body a saw blade body pivotally supported in a freely foldable and retractable manner with respect to the saw handle body and configured to be latched and locked in a use position, and a latch body attached to the saw handle body and configured to latch and lock the saw blade body, wherein the latch body comprises at least a latch section configured to extend frontward, and an operation section configured to extend rearward from the latch section , the saw blade body comprises at least a latch groove to which the latch body is to be latched, and the saw handle body comprises at least a seating recess and a receiving groove for the latch section of the latch body and the latch groove of the saw blade body to be received therein, and wherein the latch body is configured, in the state of being attached to the saw handle body , such that the latch section is spring-biased to enter into the receiving groove of the saw handle body and that the latch section is responsive to an operation of the operation section to retreat against the spring bias, characterized in that the latch body is made of single spring wire and further comprises a coil section wound into a coil form and a stop pin section configured to extend from the coil section for pinning the coil section, in that the latch section is configured to extend frontward from the coil section so as to be positioned in front of the coil section, in that the operation section is positioned in rear of the coil section , in that the seating recess is for the coil section of the latch body to be seated therein, and in that the saw handle body further comprises a pin hole for the stop pin section of the latch body to be inserted and locked therein.