Process for preparing nano- or microparticles comprising a carrier-polymer and a biologically active ingredient, wherein the process is a solvent emulsion process comprising an organic phase (OP) and an aqueous phase (AP) to form an emulsion, wherein, in the case of an oil-in-water emulsion (O/W), the organic phase (OP) comprises the biologically active ingredient dissolved or dispersed therein or wherein, in the case of a water-in-oil emulsion (W 1 /O), the aqueous phase (AP) comprises the biologically active ingredient dissolved or dispersed therein, comprising the steps: a) providing the organic phase (OP) comprising a partially water-miscible organic solvent or solvent mixture (S1), wherein the organic phase (OP) is saturated with the aqueous phase (AP) and wherein the organic phase (OP) comprises the carrier-polymer and optionally the biologically active ingredient dissolved or dispersed therein, b) providing the aqueous phase (AP), comprising an aqueous solvent or solvent mixture (S2), comprising water and a pharmaceutically acceptable salt dissolved therein, wherein the salt-containing aqueous phase is further saturated with the solvent or solvent mixture (S1) of the organic phase (OP) and is comprising an emulsion-stabilizing agent and optionally the biologically active ingredient dissolved or dispersed therein, c) mixing the organic phase (OP) and the aqueous phase (AP) to gain an oil-in-water emulsion (O/W) or a water-in-oil emulsion (W 1 /O), d) in the case of a water-in-oil emulsion (W 1 /O), addition of an excess of further aqueous phase (AP) to gain a water-in-oil-in-water emulsion (W 1 /O/W 2 ), e) removing the organic solvent or solvent mixture (S1) from the oil-in-water emulsion (O/W) from step c) or from the water-in-oil-in-water emulsion (W 1 /O/W 2 ) from step d) by evaporation and/or extraction to promote the formation of nano- or microparticles comprising the carrier polymer and the biologically active ingredient in a remaining aqueous suspension, f) separating the nano- or microparticles from the aqueous suspension. a) providing the organic phase (OP) comprising a partially water-miscible organic solvent or solvent mixture (S1), wherein the organic phase (OP) is saturated with the aqueous phase (AP) and wherein the organic phase (OP) comprises the carrier-polymer and optionally the biologically active ingredient dissolved or dispersed therein, b) providing the aqueous phase (AP), comprising an aqueous solvent or solvent mixture (S2), comprising water and a pharmaceutically acceptable salt dissolved therein, wherein the salt-containing aqueous phase is further saturated with the solvent or solvent mixture (S1) of the organic phase (OP) and is comprising an emulsion-stabilizing agent and optionally the biologically active ingredient dissolved or dispersed therein, c) mixing the organic phase (OP) and the aqueous phase (AP) to gain an oil-in-water emulsion (O/W) or a water-in-oil emulsion (W 1 /O), d) in the case of a water-in-oil emulsion (W 1 /O), addition of an excess of further aqueous phase (AP) to gain a water-in-oil-in-water emulsion (W 1 /O/W 2 ), e) removing the organic solvent or solvent mixture (S1) from the oil-in-water emulsion (O/W) from step c) or from the water-in-oil-in-water emulsion (W 1 /O/W 2 ) from step d) by evaporation and/or extraction to promote the formation of nano- or microparticles comprising the carrier polymer and the biologically active ingredient in a remaining aqueous suspension, f) separating the nano- or microparticles from the aqueous suspension. <EOS>