mhurhangee/patent-ind-claim-en huggingface dataset:
An antisense oligonucleotide conjugate comprising a. an antisense oligomer (A) of between 16 - 22 nucleotides in length, which comprises a contiguous sequence of 16 nucleotides which are complementary to a corresponding length of SEQ ID NO 31, and wherein said antisense oligomer is a LNA gapmer, and b. at least one asialoglycoprotein receptor targeting conjugate moiety (C) covalently attached to said oligomer (A). a. an antisense oligomer (A) of between 16 - 22 nucleotides in length, which comprises a contiguous sequence of 16 nucleotides which are complementary to a corresponding length of SEQ ID NO 31, and wherein said antisense oligomer is a LNA gapmer, and b. at least one asialoglycoprotein receptor targeting conjugate moiety (C) covalently attached to said oligomer (A).
A method of preparation of polycyclic, fused aromatic and heteroaromatic hydrocarbons with the formula 1, where: W = oxygen or sulfur Z and Y - are the same or different and stand for atoms of carbon or sulphur, R - stands for hydrogen, R2 - stands for alkyl, allyl, ArI and ArII - are the same or different and stand for an aromatic ring, chosen from benzene, naphthalene, anthracene, phenantrene, or pyrene, or a five-membered heteroaromatic ring chosen from pyrrole, thiophene, furan, or six-membered heteroaromatic ring chosen pyridine, pyrimidine, pyran, thiopyran, or a mixed aromatic-heteroaromatic ring chosen from indole, benzothiophene, or benzofuran; mono- or multi-substituted with alkyl group containing 1 to 20 atoms of carbon, allyl group, benzyl group, aryl group, with dialkylamine or diarylamine group , halide groups F, Cl, Br, I, ketone, aldehyde, acyl, carboxyl, imine, alkoxy, aryloxy, nitrile, nitro, and/or heteroaryl groups, characterized by that, compounds with the formula 2, or with the formula 3, where Z, Y, R, R 2 , ArI, ArII are defined as above and R---R stands for a cyclic acetal derivative are transformed by an intramolecular cyclization reaction to compounds of formula 1 in a reaction time of up to 3 hrs whereby the reaction of transformation being carried out with the use of ultrasounds at room temperature or up to 60°C, in acidic environment, in a single reaction vessel, without separation of intermediate products. W = oxygen or sulfur Z and Y - are the same or different and stand for atoms of carbon or sulphur, R - stands for hydrogen, R2 - stands for alkyl, allyl, ArI and ArII - are the same or different and stand for an aromatic ring, chosen from benzene, naphthalene, anthracene, phenantrene, or pyrene, or a five-membered heteroaromatic ring chosen from pyrrole, thiophene, furan, or six-membered heteroaromatic ring chosen pyridine, pyrimidine, pyran, thiopyran, or a mixed aromatic-heteroaromatic ring chosen from indole, benzothiophene, or benzofuran; mono- or multi-substituted with alkyl group containing 1 to 20 atoms of carbon, allyl group, benzyl group, aryl group, with dialkylamine or diarylamine group , halide groups F, Cl, Br, I, ketone, aldehyde, acyl, carboxyl, imine, alkoxy, aryloxy, nitrile, nitro, and/or heteroaryl groups, characterized by that, compounds with the formula 2, or with the formula 3, where Z, Y, R, R 2 , ArI, ArII are defined as above and R---R stands for a cyclic acetal derivative are transformed by an intramolecular cyclization reaction to compounds of formula 1 in a reaction time of up to 3 hrs whereby the reaction of transformation being carried out with the use of ultrasounds at room temperature or up to 60°C, in acidic environment, in a single reaction vessel, without separation of intermediate products.
A method performed by an access node of establishing a relationship between access nodes in a wireless communications network comprising: registering an access node (HNB1) of a plurality of access nodes (HNB1, HNB2, HNB3)with a control node of a wireless communications network; detecting at the access node (HNB1) other access nodes (HNB2, HNB3)of said plurality in the network; reporting information to the control node about the access node (HNB1), said information including identification of other access nodes (HNB2, HNB3) of said plurality detected by said access node (HNB1); and receiving a neighbour list from the control node containing a list of access nodes which are neighbouring access nodes based on said information; this step further comprising receiving an update of the list of access nodes which are neighbouring access nodes; sending a request to a subscriber station accessing the network to perform a measurement to detect an available cell in the network; receiving the measurement of the detected available cell from the subscriber station ; comparing access nodes of the detected available cells with the neighbour list received from the control node ; and reporting the detected available cell to the control node if it does not have an access node contained in the neighbour list. registering an access node (HNB1) of a plurality of access nodes (HNB1, HNB2, HNB3)with a control node of a wireless communications network; detecting at the access node (HNB1) other access nodes (HNB2, HNB3)of said plurality in the network; reporting information to the control node about the access node (HNB1), said information including identification of other access nodes (HNB2, HNB3) of said plurality detected by said access node (HNB1); and receiving a neighbour list from the control node containing a list of access nodes which are neighbouring access nodes based on said information; this step further comprising receiving an update of the list of access nodes which are neighbouring access nodes; sending a request to a subscriber station accessing the network to perform a measurement to detect an available cell in the network; receiving the measurement of the detected available cell from the subscriber station ; comparing access nodes of the detected available cells with the neighbour list received from the control node ; and reporting the detected available cell to the control node if it does not have an access node contained in the neighbour list.
A connection device for an electrical apparatus (E), comprising: a conducting part which is adapted to come into contact with a terminal (Eb) projecting from an outer surface of the electrical apparatus (E) to establish an electrical connection for charging or communication; and a housing (H), wherein the housing (H) comprises: a wall part (F); and a hole which exposes the conducting part and is formed in the wall part (F) of the housing (H), characterized in that an outer surface of the conducting part is always located closer to an inside of the housing (H) than an outer surface (F1) of the wall part (F), or at the same surface level as the outer surface (F1) of the wall part (F), the conducting part being configured to retract. a conducting part which is adapted to come into contact with a terminal (Eb) projecting from an outer surface of the electrical apparatus (E) to establish an electrical connection for charging or communication; and a housing (H), wherein the housing (H) comprises: a wall part (F); and a hole which exposes the conducting part and is formed in the wall part (F) of the housing (H), characterized in that an outer surface of the conducting part is always located closer to an inside of the housing (H) than an outer surface (F1) of the wall part (F), or at the same surface level as the outer surface (F1) of the wall part (F), the conducting part being configured to retract. a wall part (F); and a hole which exposes the conducting part and is formed in the wall part (F) of the housing (H), characterized in that an outer surface of the conducting part is always located closer to an inside of the housing (H) than an outer surface (F1) of the wall part (F), or at the same surface level as the outer surface (F1) of the wall part (F), the conducting part being configured to retract.
A polyamide fiber having a degree of orientation equal to or higher than 0.7 and equal to or lower than 0.83, wherein the degree of orientation is calculated according to the method described in the description.
An information processing device comprising: a communication unit configured to communicate with a vehicle used by a user; and a control unit configured to receive user information on the user via the communication unit, determine a usage mode of the vehicle according to a use purpose of the vehicle, the use purpose being estimated based on the user information, and send usage mode information on the usage mode to the vehicle via the communication unit, characterized in that the user information includes application information on an application operated on a terminal device of the user, the control unit is configured to estimate the use purpose based on the application information, and wherein the application information includes type information on a type of the application determined based on an application identification of the application. a communication unit configured to communicate with a vehicle used by a user; and a control unit configured to receive user information on the user via the communication unit, determine a usage mode of the vehicle according to a use purpose of the vehicle, the use purpose being estimated based on the user information, and send usage mode information on the usage mode to the vehicle via the communication unit, receive user information on the user via the communication unit, determine a usage mode of the vehicle according to a use purpose of the vehicle, the use purpose being estimated based on the user information, and send usage mode information on the usage mode to the vehicle via the communication unit, characterized in that the user information includes application information on an application operated on a terminal device of the user, the control unit is configured to estimate the use purpose based on the application information, and wherein the application information includes type information on a type of the application determined based on an application identification of the application.
A method of preparing Compound (I) comprising the step of allowing an intermediate compound of formula (A7.1) : wherein PG is a protecting group selected from a tetrahydropyranyl group (THP), a tetrahydrofuranyl group (THF), and a 1-ethoxyethyl group (EE), to react with a compound of formula (xxx7) : optionally in a suitable aprotic solvent, by addition of pyridine, optionally under activation of the carboxylic acid group or by generation of an intermediate acid chloride using a suitable reagent, and either adding one or more reagents for cleaving the protecting group or isolating compound (A9.1) and subsequently adding a reagent for cleaving the protecting group, thereby providing Compound (I) wherein PG is a protecting group selected from a tetrahydropyranyl group (THP), a tetrahydrofuranyl group (THF), and a 1-ethoxyethyl group (EE), to react with a compound of formula (xxx7) : optionally in a suitable aprotic solvent, by addition of pyridine, optionally under activation of the carboxylic acid group or by generation of an intermediate acid chloride using a suitable reagent, and either adding one or more reagents for cleaving the protecting group or isolating compound (A9.1) and subsequently adding a reagent for cleaving the protecting group, thereby providing Compound (I)
A computing device , comprising: - a non-volatile storage storing device specific identifier (ID) base data ; and - a processor configured to: - validate a certificate of an application being executed on the computing device , the certificate containing a code signer identifier (ID) for a code signer of the application ; - receive a request for an application code signer-specific ID from the application , wherein the request for the application code signer-specific ID contains the code signer ID; - generate, on the computing device , the application code signer-specific ID from the code signer ID and the device specific ID base data , wherein to generate the application code signer-specific ID the processor is configured to combine the code signer ID with the device specific ID base data and calculate a one-way hash of the combination of the code signer ID and the device specific ID base data ; and - return the generated application code signer-specific ID to the application . - a non-volatile storage storing device specific identifier (ID) base data ; and - a processor configured to: - validate a certificate of an application being executed on the computing device , the certificate containing a code signer identifier (ID) for a code signer of the application ; - receive a request for an application code signer-specific ID from the application , wherein the request for the application code signer-specific ID contains the code signer ID; - generate, on the computing device , the application code signer-specific ID from the code signer ID and the device specific ID base data , wherein to generate the application code signer-specific ID the processor is configured to combine the code signer ID with the device specific ID base data and calculate a one-way hash of the combination of the code signer ID and the device specific ID base data ; and - return the generated application code signer-specific ID to the application . - validate a certificate of an application being executed on the computing device , the certificate containing a code signer identifier (ID) for a code signer of the application ; - receive a request for an application code signer-specific ID from the application , wherein the request for the application code signer-specific ID contains the code signer ID; - generate, on the computing device , the application code signer-specific ID from the code signer ID and the device specific ID base data , wherein to generate the application code signer-specific ID the processor is configured to combine the code signer ID with the device specific ID base data and calculate a one-way hash of the combination of the code signer ID and the device specific ID base data ; and - return the generated application code signer-specific ID to the application .
A system for feeder protection in an electrical power network (EPN) nodal point comprising at least three feeders (OF1, OF2, OF3, IF1, IF2), the system comprising at least one measurement instrument (MOF1, MOF2, MOF3, MIF1, MIF2) for each feeder (OF1, OF2, OF3, IF1, IF2) for measuring at least one electrical quantity (U, I) actual in the respective feeder (OF1, OF2, OF3, IF1, IF2), at least one intelligent electronic device (IED_OF1, IED_OF2, IED_OF3, IED_IF1, IED_IF2) for each feeder (OF1, OF2, OF3, IF1, IF2) for executing, on the basis of the at least one measured electrical quantity (U, I) actual in the respective feeder (OF1, OF2, OF3, IF1, IF2), at least one first protection function (PFL1) monitoring a power system related condition of the respective feeder (OF1, OF2, OF3, IF1, IF2), and at least one central intelligent electronic device (CIED) configured to execute for the at least one feeder (OF1, OF2, OF3, IF1, IF2), on the basis of the at least one measured electrical quantity (U, I) actual in the respective feeder (OF1, OF2, OF3, IF1, IF2), at least one second protection function (PFL2) monitoring the same power system related condition of the feeder (OF1, OF2, OF3, IF1, IF2), characterized in that the central intelligent electronic device (CIED) is configured to further execute for the at least one feeder (OF1, OF2, OF3, IF1, IF2), on the basis of the at least one measured electrical quantity (U, I) actual in the other feeders connected to the same nodal point, at least one third protection function (PFL3) monitoring the same power system related condition of the feeder (OF1, OF2, OF3).
A method for cooling an object (O), comprising the steps of: - providing at least one object (O) to be cooled, - spatially distributing a cryogenic cooling liquid (L) using at least one nozzle onto said at least one object (O) so that the at least one object (O) is cooled, characterized in that said at least one nozzle is a fluidic oscillating nozzle , which is configured to generate a spatially oscillating flow (F) of said cryogenic cooling liquid (L) while maintaining a constant flow rate of the cryogenic cooling liquid (L) through the nozzle . - providing at least one object (O) to be cooled, - spatially distributing a cryogenic cooling liquid (L) using at least one nozzle onto said at least one object (O) so that the at least one object (O) is cooled, said at least one nozzle is a fluidic oscillating nozzle , which is configured to generate a spatially oscillating flow (F) of said cryogenic cooling liquid (L) while maintaining a constant flow rate of the cryogenic cooling liquid (L) through the nozzle .
A process for manufacturing polymers of sulfur-containing heterocyclic compounds, the process comprising the steps of: isolating a sulfur-containing heterocyclic compound from cracked naphtha, and reacting the sulfur-containing heterocyclic compound with a super acid to produce a polymer of the sulfur-containing heterocyclic compound. isolating a sulfur-containing heterocyclic compound from cracked naphtha, and reacting the sulfur-containing heterocyclic compound with a super acid to produce a polymer of the sulfur-containing heterocyclic compound.
A system for displaying medical images , comprising: a user interface configured to display a view of a medical image on a display device and to provide a moveable indicator identifying a moveable point positioned in the displayed medical image; and a magnifying view engine configured to generate a localized enlargement of a region of interest within the displayed medical image in response to a selection of an existing end point or an existing contour in the displayed medical image according to a first input by one or more input devices and indicated by a current position of the moveable indicator, wherein the existing end point includes an end point of two previously entered end points of a measurement of a previously segmented lesion, and the existing contour includes a contour of a previously segmented lesion, wherein the magnifying view engine is further configured to determine a size, a zoom factor, and a shape of the localized enlargement of the region of interest according to a first distance between the selected existing end point and another end point or according to a second distance of a width across an area defined by the existing contour. a user interface configured to display a view of a medical image on a display device and to provide a moveable indicator identifying a moveable point positioned in the displayed medical image; and a magnifying view engine configured to generate a localized enlargement of a region of interest within the displayed medical image in response to a selection of an existing end point or an existing contour in the displayed medical image according to a first input by one or more input devices and indicated by a current position of the moveable indicator, wherein the existing end point includes an end point of two previously entered end points of a measurement of a previously segmented lesion, and the existing contour includes a contour of a previously segmented lesion,
A method of detection and monitoring of a fluid flow, in particular of a fluid flow in filtration processes, especially of leakage in constructions and/or in ground. characterized in that a prefabricated multi-sensor integrated cable (K) comprising secured in a cable tube a power line , a data line , a structure consisting of repeated sections; wherein each section is individually addressed and controlled, and each section comprises: a heat generator in the form of a point heater , a temperature sensor connected to an A/D converter, an amplifier and a memory, and where the sections are connected to the power line and the data line, and where the prefabricated multi-sensor integrated cable is terminated with parallel, serial, USB, or other suitable connectors, and where said cable is introduced into monitored environment and connected to a power source and to a control and recording unit comprising a means for acquisition, recording, processing and visualization of measurement data, then the spatial position of each temperature sensor is determined in monitored environment, and the heat generator is supplied with a current controlled by the control and recording unit according to selected algorithm, then the temperature of monitored environment in function of space and time is measured with use of the temperature sensors, and produced data are transferred to the control and recording unit where these data are recorded and processed to obtain spatial and temporal distribution of temperature in monitored environment, and this distribution is visualized and/or stored in a memory unit of the control and recording unit.
A method for an electronic device to authenticate a smart key device , the method comprising: transmitting a first authentication request ; receiving a first authentication response in response to the first authentication request from the smart key device ; transmitting a second authentication request after receiving the first authentication response; receiving a second authentication response in response to the second authentication request from the smart key device ; the method being characterized in that it further comprises: identifying that the relay attack does not occur in case that an interval between the received first and second authentication responses is within a pre-determined duration, and identifying that the relay attack occurs in case that the interval between the received first and second authentication responses exceeds the pre-determined duration; and authenticating the smart key device in case that the relay attack does not occur. transmitting a first authentication request ; receiving a first authentication response in response to the first authentication request from the smart key device ; transmitting a second authentication request after receiving the first authentication response; receiving a second authentication response in response to the second authentication request from the smart key device ; identifying that the relay attack does not occur in case that an interval between the received first and second authentication responses is within a pre-determined duration, and identifying that the relay attack occurs in case that the interval between the received first and second authentication responses exceeds the pre-determined duration; and authenticating the smart key device in case that the relay attack does not occur.