mhurhangee/patent-ind-claim-en huggingface dataset:
A computer-implemented method for identifying a mutation in a nucleic acid, the method comprising: sequencing nucleic acid to generate a plurality of sequence reads; assembling a contig from the reads; aligning the contig to a reference sequence to provide a contig-to-reference alignment, such that both a genomic position of the contig and any differences between the contig and the reference sequence are determined, wherein the differences include both positional and variant information; aligning the individual reads back to the contig in a local, contig-specific alignment to provide read-to-contig alignments such that both a position of the reads with respect to the contig and any differences between the reads and the contig are determined, wherein the differences include both positional and variant information; mapping the read-to-contig alignments to the reference sequence using the contig-to-reference specific alignment to provide positional information relative to the reference sequence for each read, as well as any differences between the reference sequence and the reads, wherein the differences between the reference sequence and the reads are determined by: combining the differences between the reads and the contig and the differences between the contig and the reference sequence for each read, wherein each of the differences is expressed in the same format; and identifying a mutation for each read based on the combined differences. sequencing nucleic acid to generate a plurality of sequence reads; assembling a contig from the reads; aligning the contig to a reference sequence to provide a contig-to-reference alignment, such that both a genomic position of the contig and any differences between the contig and the reference sequence are determined, wherein the differences include both positional and variant information; aligning the individual reads back to the contig in a local, contig-specific alignment to provide read-to-contig alignments such that both a position of the reads with respect to the contig and any differences between the reads and the contig are determined, wherein the differences include both positional and variant information; mapping the read-to-contig alignments to the reference sequence using the contig-to-reference specific alignment to provide positional information relative to the reference sequence for each read, as well as any differences between the reference sequence and the reads, wherein the differences between the reference sequence and the reads are determined by: combining the differences between the reads and the contig and the differences between the contig and the reference sequence for each read, wherein each of the differences is expressed in the same format; and identifying a mutation for each read based on the combined differences. combining the differences between the reads and the contig and the differences between the contig and the reference sequence for each read, wherein each of the differences is expressed in the same format; and identifying a mutation for each read based on the combined differences.
A turbine stator assembly extending around an axis (A1) and comprising: - a sealing ring extending around the axis (A1) and comprising an abradable element intended to cooperate with sealing wipers carried by a rotor rotatably mounted around the axis (A1), - a plurality of crown sectors disposed circumferentially end-to-end around the axis (A1) so as to together form a crown, each crown sector being bladed, - sliding means enabling a relative movement radially with respect to the axis (A1) between the sealing ring and each of the crown sectors , the sliding means being disposed at a radially inner end of the crown formed by the plurality of crown sectors , characterised in that it comprises sealing means located radially outward from the sliding means so as to reduce leaks originating from circumferential spaces located between the circumferentially adjacent crown sectors . - a sealing ring extending around the axis (A1) and comprising an abradable element intended to cooperate with sealing wipers carried by a rotor rotatably mounted around the axis (A1), - a plurality of crown sectors disposed circumferentially end-to-end around the axis (A1) so as to together form a crown, each crown sector being bladed, - sliding means enabling a relative movement radially with respect to the axis (A1) between the sealing ring and each of the crown sectors , the sliding means being disposed at a radially inner end of the crown formed by the plurality of crown sectors ,
An immunogenic composition comprising: (a) a glycan conjugate comprising at least one glycan with a linker and a carrier, the at least one glycan being conjugated to the carrier through the linker; and (b) an adjuvant, wherein the at least one glycan with the linker has a chemical structure of formula (II): wherein: R 1 is selected from the group consisting of -F, -N 3 , -NO 2 , and R 2 is -CH 3 ; or R 1 is -OH, and R 2 is selected from the group consisting of -CH 2 F, -CH 2 N 3 , -CH 2 OH and -C≡CH. (a) a glycan conjugate comprising at least one glycan with a linker and a carrier, the at least one glycan being conjugated to the carrier through the linker; and (b) an adjuvant, wherein the at least one glycan with the linker has a chemical structure of formula (II): wherein: R 1 is selected from the group consisting of -F, -N 3 , -NO 2 , and R 2 is -CH 3 ; or R 1 is -OH, and R 2 is selected from the group consisting of -CH 2 F, -CH 2 N 3 , -CH 2 OH and -C≡CH. R 1 is selected from the group consisting of -F, -N 3 , -NO 2 , and R 2 is -CH 3 ; or R 1 is -OH, and R 2 is selected from the group consisting of -CH 2 F, -CH 2 N 3 , -CH 2 OH and -C≡CH.
A method of friction-stir welding, FSW, a joint between a first workpiece and a second workpiece, the method comprising: performing a first pass of FSW of the joint by moving therealong a first tool, comprising a first probe rotating in a first rotational direction, in a first movement direction defining a first line, on a first side of the joint, comprising: inserting the first probe to a first depth, thereby providing a first welded region; performing a second pass of FSW of the joint by moving therealong a second tool, comprising a second probe rotating in a second rotational direction, in a second movement direction defining a second line, on the first side of the joint, comprising: inserting the second probe to a second depth, thereby providing a second welded region; and fully withdrawing the second probe, thereby resulting in a second exit hole; the method being characterised by during the first pass of FSW withdrawing partially the first probe, thereby providing a first partially welded and/or unwelded region; and fully withdrawing the first probe, thereby resulting in a first exit hole; and in that the second welded region includes the first exit hole; the second exit hole is included in the first welded region wherein withdrawing partially the first probe comprises withdrawing the first probe from the first depth while moving the first tool in the first movement direction; wherein inserting the second probe to the second depth comprises inserting the second probe proximal to and/or into the first exit hole; and wherein the second welded region includes the first partially welded and/or unwelded region. performing a first pass of FSW of the joint by moving therealong a first tool, comprising a first probe rotating in a first rotational direction, in a first movement direction defining a first line, on a first side of the joint, comprising: inserting the first probe to a first depth, thereby providing a first welded region; performing a second pass of FSW of the joint by moving therealong a second tool, comprising a second probe rotating in a second rotational direction, in a second movement direction defining a second line, on the first side of the joint, comprising: inserting the second probe to a second depth, thereby providing a second welded region; and fully withdrawing the second probe, thereby resulting in a second exit hole; the method being characterised by during the first pass of FSW withdrawing partially the first probe, thereby providing a first partially welded and/or unwelded region; and fully withdrawing the first probe, thereby resulting in a first exit hole; and in that the second welded region includes the first exit hole; the second exit hole is included in the first welded region wherein withdrawing partially the first probe comprises withdrawing the first probe from the first depth while moving the first tool in the first movement direction; wherein inserting the second probe to the second depth comprises inserting the second probe proximal to and/or into the first exit hole; and wherein the second welded region includes the first partially welded and/or unwelded region.
A prosthetic heart valve system comprising: a prosthetic heart valve having an expandable stent and a prosthetic valve assembly disposed within the stent , the prosthetic valve assembly configured to allow blood to flow in a direction from an inflow end of the stent toward an outflow end of the stent and to substantially block blood from flowing from the outflow end of the stent toward the inflow end of the stent, the prosthetic heart valve including a tether connecting portion ; a collapsible and expandable anchor adapted to be disposed on or adjacent an epicardial surface of a heart of a patient; and a tether having a distal end coupled to the anchor , the tether extending proximally from the anchor , the tether defining a protrusion having a width greater than portions of the tether adjacent the protrusion , wherein the prosthetic heart valve is configured to translate along the tether toward the distal end of the tether , the protrusion of the tether configured to engage the tether connecting portion to prevent proximal movement of the prosthetic heart valve relative to the tether . a prosthetic heart valve having an expandable stent and a prosthetic valve assembly disposed within the stent , the prosthetic valve assembly configured to allow blood to flow in a direction from an inflow end of the stent toward an outflow end of the stent and to substantially block blood from flowing from the outflow end of the stent toward the inflow end of the stent, the prosthetic heart valve including a tether connecting portion ; a collapsible and expandable anchor adapted to be disposed on or adjacent an epicardial surface of a heart of a patient; and a tether having a distal end coupled to the anchor , the tether extending proximally from the anchor , the tether defining a protrusion having a width greater than portions of the tether adjacent the protrusion , wherein the prosthetic heart valve is configured to translate along the tether toward the distal end of the tether , the protrusion of the tether configured to engage the tether connecting portion to prevent proximal movement of the prosthetic heart valve relative to the tether .
A method for providing an instruction in operating a terminal device applied to a source terminal device, comprising: generating(S101), by the source terminal device, operation record information according to an obtained operation of a user performed on the source terminal device, wherein the operation record information comprises an operation page, an operation component, and an event type that correspond to the operation, wherein the operation page is a system interface of the source terminal device or interface of an application, and the operation component is a component that may be operated on the operation page to trigger entering another operation page or event; and sending(S 102), by the source terminal device, the operation record information to a target terminal device, wherein the operation record information is used to instruct the target terminal device to set, according to the operation page, the operation component, and the event type that correspond to the operation, an operation component that does not correspond to the operation component or the event type and that is on the operation page to a disabled state. generating(S101), by the source terminal device, operation record information according to an obtained operation of a user performed on the source terminal device, wherein the operation record information comprises an operation page, an operation component, and an event type that correspond to the operation, wherein the operation page is a system interface of the source terminal device or interface of an application, and the operation component is a component that may be operated on the operation page to trigger entering another operation page or event; and sending(S 102), by the source terminal device, the operation record information to a target terminal device, wherein the operation record information is used to instruct the target terminal device to set, according to the operation page, the operation component, and the event type that correspond to the operation, an operation component that does not correspond to the operation component or the event type and that is on the operation page to a disabled state.
A medical device (100; 800), comprising: a plurality of branch members (108; 808) having a proximal end and a distal end; and a first movable member (112; 812), and a second movable member (113; 813), wherein the plurality of branch members (108; 808) and the first and second movable members (112, 113; 812, 113) form a basket movable between a collapsed configuration and an expanded configuration, characterised in that the entireties of the first and second movable members (112, 113; 812, 113) are configured to move distally with respect to the plurality of branch members (108; 808). a plurality of branch members (108; 808) having a proximal end and a distal end; and a first movable member (112; 812), and a second movable member (113; 813), wherein the plurality of branch members (108; 808) and the first and second movable members (112, 113; 812, 113) form a basket movable between a collapsed configuration and an expanded configuration, characterised in that the entireties of the first and second movable members (112, 113; 812, 113) are configured to move distally with respect to the plurality of branch members (108; 808).
A computer-implemented method for validating a transaction in a blockchain system comprising a plurality of nodes, the method comprising: providing a partial signature for the transaction by a node in the blockchain system; broadcasting the partial signature to all other nodes in the blockchain system verifying , at each of the other nodes, the partial signature for the transaction; and validating the transaction by iteratively providing , broadcasting and verifying partial signatures provided by the other nodes in the blockchain system until it has been determined that a cumulative signature score based on the verified partial signatures reaches a signature threshold. providing a partial signature for the transaction by a node in the blockchain system; broadcasting the partial signature to all other nodes in the blockchain system verifying , at each of the other nodes, the partial signature for the transaction; and validating the transaction by iteratively providing , broadcasting and verifying partial signatures provided by the other nodes in the blockchain system until it has been determined that a cumulative signature score based on the verified partial signatures reaches a signature threshold.
A snow removal device comprising: a chassis supporting a power unit ; a mobility assembly operably coupled to the chassis to provide mobility for the snow removal device responsive to power provision from the power unit ; a working assembly configured to move snow to an ejection path responsive to power provision from the power unit ; and a chute assembly forming a portion of the ejection path, the chute assembly comprising a chute and a deflector , wherein the chute is rotatable via a chute rotator configured to provide at least 360 degree automated rotation of the chute , and wherein an orientation of the deflector is changeable via automated pivoting of the deflector via an electrically operable deflector adjuster ; wherein the chute rotator comprises a contact plate assembly configured to rotate with the chute and interface with a brush assembly to provide power from the power unit to the deflector adjuster . a chassis supporting a power unit ; a mobility assembly operably coupled to the chassis to provide mobility for the snow removal device responsive to power provision from the power unit ; a working assembly configured to move snow to an ejection path responsive to power provision from the power unit ; and a chute assembly forming a portion of the ejection path, the chute assembly comprising a chute and a deflector , wherein the chute is rotatable via a chute rotator configured to provide at least 360 degree automated rotation of the chute , and wherein an orientation of the deflector is changeable via automated pivoting of the deflector via an electrically operable deflector adjuster ; wherein the chute rotator comprises a contact plate assembly configured to rotate with the chute and interface with a brush assembly to provide power from the power unit to the deflector adjuster .
A resin composition containing a polyimide-based resin and a methylol-based compound, the resin composition being characterized in that the polyimide-based resin has an acid dianhydride residue and a diamine residue, and has as the diamine residue at least a residue of a polysiloxane-based diamine represented by General formula and a residue of an aromatic diamine having a hydroxyl group n is a natural number, and an average value thereof calculated from an average molecular weight of the polysiloxane-based diamine is in a range of 5 to 30; R 1 and R 2 may be individually the same or different, indicating an alkylene group or a phenylene group whose carbon number is 1 to 30; R 3 to R 6 may be individually the same or different, indicating an alkyl group, a phenyl group or a phenoxy group whose carbon number is 1 to 30, wherein as the diamine residue the residue of the aromatic diamine having a hydroxyl group is contained at 1 to 40 mol% in a total amount of the diamine residue, and wherein the aromatic diamine having a hydroxyl group is an aromatic diamine represented by any one of General formulas to : at least one of R 7 to R 10 is a hydroxyl group, and the others may be the same or different, indicating a group selected from a hydrogen atom, an alkyl group whose carbon number is 1 to 30, an alkoxy group whose carbon number 1 to 30, a halogen, a carboxyl group, a sulfone group, a nitro group, and a cyano group; X 1 indicates a group selected from a direct bond, O, S, SO, SO 2 , CO, CH 2 , C(CH 3 ) 2 and C(CF 3 ) 2 at least one of R 11 to R 18 is a hydroxyl group, and the others may be the same or different, indicating a group selected from a hydrogen atom, an alkyl group whose carbon number is 1 to 30, an alkoxy group whose carbon number 1 to 30, a halogen, a carboxyl group, a sulfone group, a nitro group, and a cyano group; X 2 and Y 2 may be individually the same or different, indicating a group selected from a direct bond, O, S, SO, SO 2 , CO, CH 2 , C(CH 3 ) 2 and C(CF 3 ) 2 ; at least one of R 19 to R 30 is a hydroxyl group, and the others may be the same or different, indicating a group selected from a hydrogen atom, an alkyl group whose carbon number is 1 to 30, an alkoxy group whose carbon number 1 to 30, a halogen, a carboxyl group, a sulfone group, a nitro group, and a cyano group; X 3 , Y 3 and Z 3 may be individually the same or different, indicating a group selected from a direct bond, O, S, SO, SO 2 , CO, CH 2 , C(CH 3 ) 2 and C(CF 3 ) 2 ; at least one of R 31 to R 46 is a hydroxyl group, and the others may be the same or different, indicating a group selected from a hydrogen atom, an alkyl group whose carbon number is 1 to 30, an alkoxy group whose carbon number 1 to 30, a halogen, a carboxyl group, a sulfone group, a nitro group, and a cyano group.
A process for preparing an aqueous suspension comprising precipitated calcium carbonate, the process comprising the steps of: a) providing at least one calcium source being essentially insoluble in water; b) providing at least one water-soluble manganese source; c) providing at least one carbonate source, and d) carbonating the at least one calcium source of step a) with the at least one carbonate source of step c) in the presence of the at least one water-soluble manganese source of step b) to convert the calcium source at least partially into precipitated calcium carbonate, wherein the at least one water-soluble manganese source of step b) is present in carbonating step d) in an amount from 100 ppm to 1000 ppm (d/d), based on the total dry weight of the at least one calcium source of step a). a) providing at least one calcium source being essentially insoluble in water; b) providing at least one water-soluble manganese source; c) providing at least one carbonate source, and d) carbonating the at least one calcium source of step a) with the at least one carbonate source of step c) in the presence of the at least one water-soluble manganese source of step b) to convert the calcium source at least partially into precipitated calcium carbonate,
An oven comprising a cooking cavity , a stirring member extending, in use, into foodstuff contained in a vessel disposed in the cooking cavity as well as drive means to provide, in use, relative movement between the stirring member and the vessel , characterized in that the oven comprises a displacement device to move the stirring member from outside the cooking cavity through an opening in a wall bounding the cooking cavity into the cooking cavity as well as, in use, into the vessel disposed in the cooking cavity .
A computing device , comprising: one or more processors configured to execute instructions that cause the one or more processors to: acquire pressure data measured by at least one pressure sensor disposed proximate to a filter house in an intake of a gas turbine engine system ; characterized in that the instructions cause the one or more processors to: derive an airflow or an air mass flow through a duct of the intake using a thermodynamic model of the gas turbine engine system based at least on the pressure data; derive an intake pressure drop in the duct using at least the pressure data; derive a loss parameter of the filter house by combining the air mass or air mass flow, and the intake pressure drop; derive a pressure loss model based on the loss parameter over a period of time; and determine a condition of the filter house based on the pressure loss model. derive an airflow or an air mass flow through a duct of the intake using a thermodynamic model of the gas turbine engine system based at least on the pressure data; derive an intake pressure drop in the duct using at least the pressure data; derive a loss parameter of the filter house by combining the air mass or air mass flow, and the intake pressure drop; derive a pressure loss model based on the loss parameter over a period of time; and determine a condition of the filter house based on the pressure loss model.
A method performed by a terminal (330; 430) in a communication system, the method comprising: identifying configuration information on a plurality of logical channel identifiers; identifying a resource for transmitting a scheduling request of uplink data to be transmitted, based on a logical channel identifier for the uplink data; and transmitting, to a base station (300; 400, 410), based on the identified resource, the scheduling request of the uplink data for requesting an uplink scheduling for the uplink data. identifying configuration information on a plurality of logical channel identifiers; identifying a resource for transmitting a scheduling request of uplink data to be transmitted, based on a logical channel identifier for the uplink data; and transmitting, to a base station (300; 400, 410), based on the identified resource, the scheduling request of the uplink data for requesting an uplink scheduling for the uplink data.