mhurhangee/patent-ind-claim-en huggingface dataset:
An isolated cell comprising an insertion or a deletion in an endogenous PD1 gene within or between the sequences shown in SEQ ID NO:56 and SEQ ID NO:60 of the endogenous PD1 gene, wherein the insertion or deletion is made following cleavage of the endogenous PD1 gene by first and second zinc finger nucleases, each zinc finger nuclease comprising a zinc finger DNA-binding domain and a nuclease domain, wherein the first zinc finger nuclease comprises a zinc finger DNA-binding domain that binds to the target site shown in SEQ ID NO:56, the zinc finger DNA-binding domain comprising a protein designated 12942 or 22237 as shown in Table 2 and the second zinc finger nuclease comprises a zinc finger DNA-binding domain that binds to the target site shown in SEQ ID NO:60, the zinc finger DNA-binding domain comprising a protein designated 18759, 25005, 25006, 25010, 25011, 25012, 25013, 25014, 25015, 25017, 25022, 25023, 25025, 25027, 25028, 25030, 25031, 25032, 25034, 25036, 25040 and 25041 as shown in Table 2.
A product order fulfillment system comprising: multiple decks arrayed at different levels and defining multilevel decks; at least one autonomous transport vehicle disposed on each of the multilevel decks, and configured for holding and transporting a pickface on each deck; more than one lift , traversing and connecting more than one level of the multilevel decks, and arranged for lifting and lowering the pickface from the multilevel decks; and at least one pickface transfer station (TS) on each deck interfacing between the autonomous transport vehicle on the deck and a respective lift of the more than one lift to effect transfer of the pickface between the autonomous transport vehicle and the lift ; characterized in that the more than one lift defines a fulfillment stream of mixed case pickfaces outbound from the multilevel decks to a load fill, and at least one stream of the fulfillment stream, from one of the more than one lift , has an ordered sequence of streaming pickfaces wherein the ordered sequence of streaming pickfaces in the least one stream is based on another stream of the fulfilment stream from another of the more than one lift . multiple decks arrayed at different levels and defining multilevel decks; at least one autonomous transport vehicle disposed on each of the multilevel decks, and configured for holding and transporting a pickface on each deck; more than one lift , traversing and connecting more than one level of the multilevel decks, and arranged for lifting and lowering the pickface from the multilevel decks; and at least one pickface transfer station (TS) on each deck interfacing between the autonomous transport vehicle on the deck and a respective lift of the more than one lift to effect transfer of the pickface between the autonomous transport vehicle and the lift ; characterized in that the more than one lift defines a fulfillment stream of mixed case pickfaces outbound from the multilevel decks to a load fill, and at least one stream of the fulfillment stream, from one of the more than one lift , has an ordered sequence of streaming pickfaces wherein the ordered sequence of streaming pickfaces in the least one stream is based on another stream of the fulfilment stream from another of the more than one lift .
A method for monitoring, during a flight, an aircraft engine in operation, the method being characterized in that it comprises performing steps of (a) For at least one characteristic frequency of the operation of the engine , measuring by a sensor disposed in the engine at least one vibration level value synchronous with said characteristic frequency; (b) For at least one module of said engine , estimating by data-processing means an unbalance value of said module as a function of the measured vibration level value(s) and of at least one sensitivity coefficient of said module associated with said characteristic frequency, said sensitivity coefficient being a predetermined, non-dimensional parameter, reflecting the perceptive impact of the vibrations caused by an unbalance on people or objects carried by the aircraft ; (c) Estimating by the data-processing means a balancing margin of said module as a function of the unbalance value of said module and a maximum threshold associated with the module; (d) Estimating a remaining number of flights of said aircraft before balancing and/or an indicator of quality of a previous balancing as a function of the estimated balancing margin(s) and of data representative of past balancings of the engine stored in a database stored on data-storage means , and transmitting to interface means . (a) For at least one characteristic frequency of the operation of the engine , measuring by a sensor disposed in the engine at least one vibration level value synchronous with said characteristic frequency; (b) For at least one module of said engine , estimating by data-processing means an unbalance value of said module as a function of the measured vibration level value(s) and of at least one sensitivity coefficient of said module associated with said characteristic frequency, said sensitivity coefficient being a predetermined, non-dimensional parameter, reflecting the perceptive impact of the vibrations caused by an unbalance on people or objects carried by the aircraft ; (c) Estimating by the data-processing means a balancing margin of said module as a function of the unbalance value of said module and a maximum threshold associated with the module; (d) Estimating a remaining number of flights of said aircraft before balancing and/or an indicator of quality of a previous balancing as a function of the estimated balancing margin(s) and of data representative of past balancings of the engine stored in a database stored on data-storage means , and transmitting to interface means .
A system for assisting a rescuer in providing resuscitative treatment to a victim , the system comprising: a processor , a memory , and associated circuitry configured to detect compression waveform features (901-908, 910, 912, 914, 920, 930, 935, 940, 945, 950) characteristic of manual chest compressions, automated chest compressions, and mechanically assisted active compression-decompression, ACD, chest compressions, at least one output device communicatively coupled to the processor, and at least one motion sensor , communicatively coupled to the processor and configured to generate signals indicative of motion of the chest of the victim during chest compressions, wherein the processor is further configured to: receive the signals indicative of the motion of the chest, generate a compression waveform based on the signals indicative of the motion of the chest, identify the compression waveform as one of a manual chest compression waveform, an automated chest compression waveform, and a mechanically assisted ACD chest compression waveform based on one or more compression waveform features in the compression waveform, and control the at least one output device to selectively provide chest compression feedback to the rescuer based at least in part on the identified compression waveform. a processor , a memory , and associated circuitry configured to detect compression waveform features (901-908, 910, 912, 914, 920, 930, 935, 940, 945, 950) characteristic of manual chest compressions, automated chest compressions, and mechanically assisted active compression-decompression, ACD, chest compressions, at least one output device communicatively coupled to the processor, and at least one motion sensor , communicatively coupled to the processor and configured to generate signals indicative of motion of the chest of the victim during chest compressions, wherein the processor is further configured to: receive the signals indicative of the motion of the chest, generate a compression waveform based on the signals indicative of the motion of the chest, identify the compression waveform as one of a manual chest compression waveform, an automated chest compression waveform, and a mechanically assisted ACD chest compression waveform based on one or more compression waveform features in the compression waveform, and control the at least one output device to selectively provide chest compression feedback to the rescuer based at least in part on the identified compression waveform. receive the signals indicative of the motion of the chest, generate a compression waveform based on the signals indicative of the motion of the chest, identify the compression waveform as one of a manual chest compression waveform, an automated chest compression waveform, and a mechanically assisted ACD chest compression waveform based on one or more compression waveform features in the compression waveform, and control the at least one output device to selectively provide chest compression feedback to the rescuer based at least in part on the identified compression waveform.
A system for tracking and analysing display case usage to determine the effectiveness of advertising content, the system comprising: a display case having a door capable of movement between an opened position, whereby a plurality of consumer products stored in the display case may be accessed, and a closed position, whereby the display case is substantially sealed; a transparent electronic display housed within the door and configured to display a variety of advertising content; a sensor configured to detect whether the door is in the opened position; and a CPU electrically connected to the transparent electronic display and the sensor, characterised in that the CPU is configured to receive data from the sensor indicating whether the door is in the opened position and data from the transparent electronic display representing the advertising content displayed on the transparent electronic display when the sensor indicates that the door is in the opened position and store the data from the transparent electronic display as an effective advertisement where the data from the sensor indicates that the door was placed in the opened position while the advertising content was displayed on the transparent electronic display an average number of times during a period of time exceeding a target number by at least a predetermined amount. a display case having a door capable of movement between an opened position, whereby a plurality of consumer products stored in the display case may be accessed, and a closed position, whereby the display case is substantially sealed; a transparent electronic display housed within the door and configured to display a variety of advertising content; a sensor configured to detect whether the door is in the opened position; and a CPU electrically connected to the transparent electronic display and the sensor, characterised in that the CPU is configured to receive data from the sensor indicating whether the door is in the opened position and data from the transparent electronic display representing the advertising content displayed on the transparent electronic display when the sensor indicates that the door is in the opened position and store the data from the transparent electronic display as an effective advertisement where the data from the sensor indicates that the door was placed in the opened position while the advertising content was displayed on the transparent electronic display an average number of times during a period of time exceeding a target number by at least a predetermined amount.
Fly/drive vehicle having a road riding condition and a flying condition, and being easily convertible between the road riding condition and the flying condition, the vehicle comprising: a body with a passenger compartment and a drive compartment , at least one steered wheel and at least one driven wheel , and a propulsion propeller ; driving means arranged within the drive compartment of the car body , for driving the propeller in flying condition and for driving the driven wheels in road riding condition; wherein a portion of the drive compartment remote from the propeller is wider than a portion of the drive compartment close to the propeller; wherein the driving means comprise two separate engines arranged next to each other in the remote portion of the drive compartment ; wherein the propeller comprises a propeller base attached to a propeller gear wheel ; wherein the propeller gear wheel is in engagement with a first drive output gear wheel that is coupled to a first one of said engines via a first cardan axle , and in engagement with a second drive output gear wheel that is coupled to a second one of said engines via a second cardan axle ; wherein, the two cardan axles are oblique in horizontal direction and possibly in vertical direction such that, in the direction from the engines to the propeller, their mutual distance reduces and they possibly rise. a body with a passenger compartment and a drive compartment , at least one steered wheel and at least one driven wheel , and a propulsion propeller ; driving means arranged within the drive compartment of the car body , for driving the propeller in flying condition and for driving the driven wheels in road riding condition; wherein a portion of the drive compartment remote from the propeller is wider than a portion of the drive compartment close to the propeller; wherein the driving means comprise two separate engines arranged next to each other in the remote portion of the drive compartment ; wherein the propeller comprises a propeller base attached to a propeller gear wheel ; wherein the propeller gear wheel is in engagement with a first drive output gear wheel that is coupled to a first one of said engines via a first cardan axle , and in engagement with a second drive output gear wheel that is coupled to a second one of said engines via a second cardan axle ; wherein, the two cardan axles are oblique in horizontal direction and possibly in vertical direction such that, in the direction from the engines to the propeller, their mutual distance reduces and they possibly rise.
A display device , comprising: a display unit configured to display a video image playing a plurality of frames and a timeline interface corresponding to the video image; a control input sensing unit configured to detect a control input and deliver the detected control input to a processor ; and the processor configured to control the display unit and the control input sensing unit , characterized in that the processor is further configured to: determine a correlation of the plurality of frames contained in the video frame based on matched regions from images set to each of the plurality of frames, set frames of which correlation is greater than a predetermined ratio among the plurality of frames contained in the video image as a first frame group , set a first point and a second point on the timeline interface based on the first frame group , set a first panorama section between the set first point and the set second point, display a first panorama interface corresponding to the first panorama section in the timeline interface . a display unit configured to display a video image playing a plurality of frames and a timeline interface corresponding to the video image; a control input sensing unit configured to detect a control input and deliver the detected control input to a processor ; and the processor configured to control the display unit and the control input sensing unit , characterized in that the processor is further configured to: determine a correlation of the plurality of frames contained in the video frame based on matched regions from images set to each of the plurality of frames, set frames of which correlation is greater than a predetermined ratio among the plurality of frames contained in the video image as a first frame group , set a first point and a second point on the timeline interface based on the first frame group , set a first panorama section between the set first point and the set second point, display a first panorama interface corresponding to the first panorama section in the timeline interface . determine a correlation of the plurality of frames contained in the video frame based on matched regions from images set to each of the plurality of frames, set frames of which correlation is greater than a predetermined ratio among the plurality of frames contained in the video image as a first frame group , set a first point and a second point on the timeline interface based on the first frame group , set a first panorama section between the set first point and the set second point, display a first panorama interface corresponding to the first panorama section in the timeline interface .
Street furniture such as bollards , lights, signs, guardrails, hoop guards, bicycle stands, waste bins, benches, the street furniture comprising an embedding sleeve , or an embedding sleeve with a ground sleeve , insertable in the ground and a hollow pole or strut insertable therein in a form-fit manner and detachably connectable therewith, the embedding sleeve , respectively the embedding sleeve with the ground sleeve , intended for receiving the vertical hollow pole or strut being equipped with a first fixator and a second fixator , and the fixators each being disposed at different levels within the embedding sleeve , respectively the embedding sleeve with the ground sleeve , characterized in that the street furniture has a connecting piece , the fixators enabling receiving hollow poles or struts of a further piece of street furniture using differently designed connecting systems by the connecting piece being insertable in the lower end of the hollow pole or strut of the further piece of furniture, the lower end of the connecting piece being connectable to the embedding sleeve using a bayonet-like catch in an upper opening of the embedding sleeve forming the second fixator on the upper level .
A method of directing content preparation for a 5G media streaming, 5GMS, network performed by at least one processor implementing a 5GMS application provider, the method comprising: creating a content preparation template, by the 5GMS application provider, wherein the content preparation template includes first information specifying instructions for content preparation, and second information specifying instructions for content output; establishing a first provisioning session with a 5GMS application function; transmitting the content preparation template to the 5GMS application function in the first provisioning session, wherein the transmitting causes an instantiation of a content preparation process and resource allocation process, wherein the 5GMS application function requests to allocate 5GMS content preparation resources and 5GMS content distribution resources, and wherein the content preparation process is performed at the time of the request or right before downlink streaming of the content; and receiving a first acknowledgement from the 5GMS application function, wherein the first acknowledgement indicates an allocation of at least one of content preparation resources and content distribution resources. creating a content preparation template, by the 5GMS application provider, wherein the content preparation template includes first information specifying instructions for content preparation, and second information specifying instructions for content output; establishing a first provisioning session with a 5GMS application function; transmitting the content preparation template to the 5GMS application function in the first provisioning session, wherein the transmitting causes an instantiation of a content preparation process and resource allocation process, wherein the 5GMS application function requests to allocate 5GMS content preparation resources and 5GMS content distribution resources, and wherein the content preparation process is performed at the time of the request or right before downlink streaming of the content; and receiving a first acknowledgement from the 5GMS application function, wherein the first acknowledgement indicates an allocation of at least one of content preparation resources and content distribution resources.
A pouch product suitable for application in an oral cavity of a human comprising a sealable pouch material containing a filling material comprising i) 0 to 10wt% cannabis, ii) 0 to 10wt% nicotine, whereby nicotine is either iia) present in the form of tobacco or iib) present as nicotine pure and as nicotine salicylic acid salt at a ratio of pure to salt of 0.20-1:1, and up to 100wt% of one or more of iii) a sweetener, iv) a pH regulator, and optionally v) essential oil as taste agent, characterized in that the filling material further comprises vi) up to 76wt% of a filler consisting of vi-1) 42 to 60wt% microcrystalline cellulose and vi-2) 11 to 22wt % potato fibers, whereby a ratio between microcrystalline cellulose and potato fibers is 2.0-5:1, and vii) 0.1 to 5wt% of xanthan gum as a wetting agent, whereby a ratio between microcrystalline cellulose, potato fibers and xanthan gum is 2.0-4.8:1:0.001-0.4, wherein wt% are weight percentages of the total weight of the filling material. i) 0 to 10wt% cannabis, ii) 0 to 10wt% nicotine, whereby nicotine is either iia) present in the form of tobacco or iib) present as nicotine pure and as nicotine salicylic acid salt at a ratio of pure to salt of 0.20-1:1, and up to 100wt% of one or more of iii) a sweetener, iv) a pH regulator, and optionally v) essential oil as taste agent, iia) present in the form of tobacco or iib) present as nicotine pure and as nicotine salicylic acid salt at a ratio of pure to salt of 0.20-1:1, and up to 100wt% of one or more of iii) a sweetener, iv) a pH regulator, and optionally v) essential oil as taste agent, vi) up to 76wt% of a filler consisting of vi-1) 42 to 60wt% microcrystalline cellulose and vi-2) 11 to 22wt % potato fibers, whereby a ratio between microcrystalline cellulose and potato fibers is 2.0-5:1, and vi-1) 42 to 60wt% microcrystalline cellulose and vi-2) 11 to 22wt % potato fibers, whereby a ratio between microcrystalline cellulose and potato fibers is 2.0-5:1, and vii) 0.1 to 5wt% of xanthan gum as a wetting agent, whereby a ratio between microcrystalline cellulose, potato fibers and xanthan gum is 2.0-4.8:1:0.001-0.4, wherein wt% are weight percentages of the total weight of the filling material.
A process for producing a polymer comprising: polymerizing a monomer dissolved in a solvent in the presence of a catalyst system to obtain a first effluent stream, comprising a solution of polymer in the solvent; heating the first effluent stream in at least one spiral heat exchanger to produce a second effluent stream, wherein the first effluent stream flows through the at least one spiral heat exchanger in a cross-flow direction relative to spirals of the at least one spiral heat exchanger; and separating the second effluent stream in a vessel into: a third effluent stream comprising polymer substantially free of the solvent and a recycle stream comprising the solvent and unreacted monomer. polymerizing a monomer dissolved in a solvent in the presence of a catalyst system to obtain a first effluent stream, comprising a solution of polymer in the solvent; heating the first effluent stream in at least one spiral heat exchanger to produce a second effluent stream, wherein the first effluent stream flows through the at least one spiral heat exchanger in a cross-flow direction relative to spirals of the at least one spiral heat exchanger; and separating the second effluent stream in a vessel into: a third effluent stream comprising polymer substantially free of the solvent and a recycle stream comprising the solvent and unreacted monomer.