mhurhangee/patent-ind-claim-en huggingface dataset:
A method of preparing an outer membrane vesicle (OMV) from a Gram-negative bacterium, wherein: - the OMV comprises a lipoprotein consisting of a heterologous protein, or an immunogenic fragment thereof, carrying an acylated N-terminal cysteine, - the lipoprotein is expressed in the membrane of the OMV - the OMV is capable of eliciting an immune response to the heterologous protein or to a fragment thereof when administered to a mammal, said method comprising the following steps: (i) expressing, in a Gram-negative bacterium, the heterologous protein fused to a leader sequence carrying a C-terminal Cysteine, wherein said leader sequence comprises the sequence Leu-(Ala/Ser)-(Gly/Ala)-Cys (lipobox), (ii) isolating the OMV containing the heterologous protein. - the OMV comprises a lipoprotein consisting of a heterologous protein, or an immunogenic fragment thereof, carrying an acylated N-terminal cysteine, - the lipoprotein is expressed in the membrane of the OMV - the OMV is capable of eliciting an immune response to the heterologous protein or to a fragment thereof when administered to a mammal, (i) expressing, in a Gram-negative bacterium, the heterologous protein fused to a leader sequence carrying a C-terminal Cysteine, wherein said leader sequence comprises the sequence Leu-(Ala/Ser)-(Gly/Ala)-Cys (lipobox), (ii) isolating the OMV containing the heterologous protein.
A clip used for removably attaching or restraining one member with respect to another member , the clip comprising a first head part disposed to close a through-hole of the one member among through-holes formed in the both members , and a leg part inserted into the through-holes and engageable with a back side of the other member , wherein the clip includes, at least, a first member that includes the first head part , a suction part protruding around the first head part and an axial insertion hole , and a second member that includes a second head part which overlaps with the first head part of the first member and forms a watertight structure with the first head part of the first member , and the leg part vertically provided from the second head part and inserted into the insertion hole , whereby the first head part and the suction part are molded by two-sided split upper and lower molds , the suction part protrudes in a form of an umbrella or dish from the lower circumference of the first head part and an inner surface of the suction part is formed as a seal surface adapted to be contacted with a surface of the one member , and the seal surface is formed so that a parting line (PL) does not enter therein.
A first software defined network, SDN, controller as a parent controller, the first SDN controller communicating with a second SDN controller as a first child controller of the first SDN controller and communicating with a third SDN controller as a second child controller of the first SDN controller according to a border gateway protocol, BGP, the first SDN controller being configured to: • receive a request to create an end-to-end, E2E, tunnel from a source to a destination; • compute a path for the E2E tunnel based on the topology of the domain controlled by the second SDN controller and based on the topology of the domain controlled by the third SDN controller ; • transmit, to the second SDN controller , a first request used to instruct the second SDN controller to create, through the domain controlled by the second SDN controller , a first tunnel segment of the E2E tunnel along the path, wherein the first request indicates at least a start node and an end node of the first tunnel segment; • transmit, to the third SDN controller , a second request used to instruct the third SDN controller to create, through the domain controlled by the third SDN controller , a second tunnel segment of the E2E tunnel along the path, wherein the second request indicates at least a start node and an end node of the second tunnel segment. • receive a request to create an end-to-end, E2E, tunnel from a source to a destination; • compute a path for the E2E tunnel based on the topology of the domain controlled by the second SDN controller and based on the topology of the domain controlled by the third SDN controller ; • transmit, to the second SDN controller , a first request used to instruct the second SDN controller to create, through the domain controlled by the second SDN controller , a first tunnel segment of the E2E tunnel along the path, wherein the first request indicates at least a start node and an end node of the first tunnel segment; • transmit, to the third SDN controller , a second request used to instruct the third SDN controller to create, through the domain controlled by the third SDN controller , a second tunnel segment of the E2E tunnel along the path, wherein the second request indicates at least a start node and an end node of the second tunnel segment.
A carrying system comprising: a first carrying strap adapted to extend from a first position of an upper back section of said carrying system over a first shoulder of a user substantially diagonally downwards towards the stomach area or solar plexus of said user; a second carrying strap adapted to extend from a second position of said upper back section of said carrying system over a second shoulder of said user substantially diagonally downwards towards the stomach area or solar plexus of said user; a third carrying strap adapted to extend from a first position of a lower back section of said carrying system under a first arm of said user substantially diagonally upwards towards the stomach area or solar plexus of said user; and a fourth carrying strap adapted to extend from a second position of said lower back section of said carrying system under a second arm of said user substantially diagonally upwards towards the stomach area or solar plexus of said user; wherein said second and fourth carrying straps are provided with a connecting body which is connected to an end of each of the two carrying straps , and each and one of the remaining first and third carrying straps are provided with each a fastening body which is connected to the corresponding end of said carrying strap; wherein said connecting body is adapted to connect said respective fastening bodies ; and wherein each and one of said fastening bodies is adapted to be pressed into the connecting body and locked there; characterized in that each fastening body is arranged with a release portion adapted to disengage the fastening body from the connecting body so that the carrying system may be disengaged from a carrying user; that said release portions are arranged to be placed adjacent each other when locked in the connecting body to enable easy access to said release portions ; that said release portions are arranged in a recess (7") of said connecting body ; and that said recess (7") is arranged between said two respective fastening bodies when said fastening bodies are pressed into the connecting body to enable easy one-handed disengagement of the carrying system from said carrying user.
An optical diode comprising: a circular polarisation splitter arranged to receive at least partially unpolarised light and output right-handed circular polarised light along a first optical path and left-handed circular polarised light along a second optical path; a first circular polariser arranged on the first optical path, wherein the first polariser is arranged to transmit right-handed circular polarised light and reflect left-handed circular polarised light; and a second circular polariser arranged on the second optical path, wherein the second polariser is arranged to transmit left-handed circular polarised light and reflect right-handed circular polarised light. a circular polarisation splitter arranged to receive at least partially unpolarised light and output right-handed circular polarised light along a first optical path and left-handed circular polarised light along a second optical path; a first circular polariser arranged on the first optical path, wherein the first polariser is arranged to transmit right-handed circular polarised light and reflect left-handed circular polarised light; and a second circular polariser arranged on the second optical path, wherein the second polariser is arranged to transmit left-handed circular polarised light and reflect right-handed circular polarised light.
System for assembling a part in the aperture of a component the part being arranged to be integral with an arbour, the component being arranged to be rotated, the assembly system including a system for securing the component and the part to each other, which includes at least one pawl device for making the component and the part move integrally with each other, regardless of the rotational movement of the component, said at least one pawl device including an elastic arm forming a pawl, which locks a mortise and tenon type assembly in order to prevent any relative movements between the component and the part characterised in that : - the arm is formed in the component and also forms the tenon , the mortise being formed in the part , or - the arm is formed in the component and includes the mortise , the tenon being formed in the part , or - the arm is formed in the component and forms a wall of the mortise , the remainder of the mortise being formed in the component and the tenon being formed in the part , or - the arm is formed in the part and includes the mortise , the tenon being formed in the component , or - the arm is formed in the part and forms a wall of the mortise , the remainder of the mortise being formed in the part and the tenon being formed in the component . - the arm is formed in the component and also forms the tenon , the mortise being formed in the part , or - the arm is formed in the component and includes the mortise , the tenon being formed in the part , or - the arm is formed in the component and forms a wall of the mortise , the remainder of the mortise being formed in the component and the tenon being formed in the part , or - the arm is formed in the part and includes the mortise , the tenon being formed in the component , or - the arm is formed in the part and forms a wall of the mortise , the remainder of the mortise being formed in the part and the tenon being formed in the component .
A method for quick quantification assay of 25-hydroxyvitamin D based on fluorescence measurement using lateral flow cartridge comprising: (a) preparing a first reaction product by mixing a biological sample with a releasing buffer followed by reaction for 3 to 7 minutes at 32 to 37°C; (b) preparing a second reaction product by adding a detection buffer to the first reaction product of the step (a) followed by reaction for 13 to 17 minutes at 32 to 37°C; and (c) loading the second reaction product of the step (b) in a lateral flow cartridge followed by reaction for 6 to 10 minutes and measuring fluorescence intensity using a fluorescence meter, wherein the releasing buffer of the step (a) contains 0.4 to 0.6 N sodium hydroxide and 35 to 45% (v/v) DMSO (dimethyl sulfoxide), and wherein the detection buffer of the step (b) contains fluorescent-labeled anti-25-hydroxyvitamin D antibody, and wherein the lateral flow cartridge of the step (c) has test strip form in which a sample injection part to which a sample is injected; a test line placed at a certain distance from the sample injection part, to which a complex of bovine serum albumin and 25-hydroxyvitamin D is immobilized; and a control line to which rabbit IgG is immobilized are provided in order. (a) preparing a first reaction product by mixing a biological sample with a releasing buffer followed by reaction for 3 to 7 minutes at 32 to 37°C; (b) preparing a second reaction product by adding a detection buffer to the first reaction product of the step (a) followed by reaction for 13 to 17 minutes at 32 to 37°C; and (c) loading the second reaction product of the step (b) in a lateral flow cartridge followed by reaction for 6 to 10 minutes and measuring fluorescence intensity using a fluorescence meter, wherein the releasing buffer of the step (a) contains 0.4 to 0.6 N sodium hydroxide and 35 to 45% (v/v) DMSO (dimethyl sulfoxide), and wherein the detection buffer of the step (b) contains fluorescent-labeled anti-25-hydroxyvitamin D antibody, and wherein the lateral flow cartridge of the step (c) has test strip form in which a sample injection part to which a sample is injected; a test line placed at a certain distance from the sample injection part, to which a complex of bovine serum albumin and 25-hydroxyvitamin D is immobilized; and a control line to which rabbit IgG is immobilized are provided in order.
A method of making the compound AR-67 comprising: forming AP4622-1 from propane-1,3-dithiol and 3-hydroxybenzaldehyde; adding a solution of TBSCl ( tert -butyldimethylsilyl chloride) to a solution of AP4622-1 and imidazole to form AP4622-2 adding n-BuLi to a solution of AP4622-2 to form a first mixture and adding TBSCl to the mixture to form AP4622-3 adding a solution of AP4622-3 to a solution of NBS ( N bromosuccinimide to form AP4622-4 adding tetrabutylammonium fluoride trihydrate to a solution of AP4622-4 to form AP4622-5 adding HNO 3 to a solution of AP4622-5 to form AP4622-6 adding tin powder to a mixture of AP4622-6 to form AP4622 and combining AP4622 and s -Trione in the presence of TsOH (toluenesulfonic acid) to form AR67. forming AP4622-1 from propane-1,3-dithiol and 3-hydroxybenzaldehyde; adding a solution of TBSCl ( tert -butyldimethylsilyl chloride) to a solution of AP4622-1 and imidazole to form AP4622-2 adding n-BuLi to a solution of AP4622-2 to form a first mixture and adding TBSCl to the mixture to form AP4622-3 adding a solution of AP4622-3 to a solution of NBS ( N bromosuccinimide to form AP4622-4 adding tetrabutylammonium fluoride trihydrate to a solution of AP4622-4 to form AP4622-5 adding HNO 3 to a solution of AP4622-5 to form AP4622-6 adding tin powder to a mixture of AP4622-6 to form AP4622 and combining AP4622 and s -Trione in the presence of TsOH (toluenesulfonic acid) to form AR67.
Method for the continuous casting of metal strands, in particular of rolling ingots made of aluminium or an aluminium alloy, in which - the liquid metal is simultaneously cast via a plurality of moulds into a plurality of metal strands, - the moulds each have a narrow side and a broad side , wherein all moulds have a uniform length of the narrow side , so that the metal strands have equal thicknesses after casting, - at least one of the moulds used has a broad side , whose length differs from the length of the broad side of the other simultaneously used moulds , - for each mould used, a sprue stone is provided, which is arranged on a casting table and is provided for receiving the starter strands, - wherein the casting of the metal strands comprises a mould filling phase with fixed casting table , in which a plurality of starter strands is cast into the associated sprue stones , and - the casting comprises a continuous casting phase in which the casting table is lowered and a plurality of metal strands is cast, characterised in that the depth (T) of the sprue stone for each mould is at least 50 mm, the mould filling phase is started simultaneously for all moulds with an identical filling speed, the casting process is stopped for the moulds that have reached the necessary metal level for starting the continuous casting phase and the continuous casting phase is started as soon as all moulds have reached the necessary metal level for the continuous casting phase. - the liquid metal is simultaneously cast via a plurality of moulds into a plurality of metal strands, - the moulds each have a narrow side and a broad side , wherein all moulds have a uniform length of the narrow side , so that the metal strands have equal thicknesses after casting, - at least one of the moulds used has a broad side , whose length differs from the length of the broad side of the other simultaneously used moulds , - for each mould used, a sprue stone is provided, which is arranged on a casting table and is provided for receiving the starter strands, - wherein the casting of the metal strands comprises a mould filling phase with fixed casting table , in which a plurality of starter strands is cast into the associated sprue stones , and - the casting comprises a continuous casting phase in which the casting table is lowered and a plurality of metal strands is cast,
Convertible garment intended to be worn in several configurations of wearing by an individual/user (U) relative to which are defined a symmetric longitudinal plane (P1) and the terms front, back, left and right, the garment comprising: - and front panel and a back panel bound together at an intermediary area (P2) by a left junction and a right junction located on both sides of a central aperture, with an indentation extending from a front side of the central aperture, - a lash comprising a central section fixed on the edge of the central aperture but not on the edge of the indentation, and free sections extending from both sides of the central section, - the garment being deprived of a stitching connection joining the lateral borders of the front and back panels, - at least two seam connections, a right-hand and a left-hand seam connection, linking the front and back panels, the aforementioned seam connections being arranged symmetrical on both sides of the longitudinal plane of symmetry (P1), away from the lateral borders , wherein the developed length of the edge of the central aperture, excluding the indentation, denoted LD, is comprised between 60 and 100cm, preferably between 70cm and 95cm, and more preferably between 78 cm and 86 cm, and the developed length of the indentation denoted LF is comprised between 10 cm and 25 cm, preferably between 14 cm and 25 cm, and more preferably between 15 cm and 20 cm, whereby the garment can be worn either in a tunic configuration, a poncho configuration, a backless dress configuration, a skirt configuration, an asymmetric configuration, or in a sarouel configuration. - and front panel and a back panel bound together at an intermediary area (P2) by a left junction and a right junction located on both sides of a central aperture, with an indentation extending from a front side of the central aperture, - a lash comprising a central section fixed on the edge of the central aperture but not on the edge of the indentation, and free sections extending from both sides of the central section, - the garment being deprived of a stitching connection joining the lateral borders of the front and back panels, - at least two seam connections, a right-hand and a left-hand seam connection, linking the front and back panels, the aforementioned seam connections being arranged symmetrical on both sides of the longitudinal plane of symmetry (P1), away from the lateral borders , wherein the developed length of the edge of the central aperture, excluding the indentation, denoted LD, is comprised between 60 and 100cm, preferably between 70cm and 95cm, and more preferably between 78 cm and 86 cm, and the developed length of the indentation denoted LF is comprised between 10 cm and 25 cm, preferably between 14 cm and 25 cm, and more preferably between 15 cm and 20 cm, whereby the garment can be worn either in a tunic configuration, a poncho configuration, a backless dress configuration, a skirt configuration, an asymmetric configuration, or in a sarouel configuration.
Switching device , comprising: - a housing ; - a switching module (3, 3', 3") which is arranged inside the housing and has several switching elements and a cooling boxes with cooling channel enclosed therein, wherein the cooling channels of the various cooling boxes being hydraulically connected to one another via lines ; - an insulating liquid , which surrounds the switching module (3, 3', 3"), inside the housing ; and - a cooling circuit comprising a pump , the cooling channel and a heat exchanger ; wherein: - the inside of the housing and the cooling circuit are hydraulically connected to each other in such way that the insulating liquid is used in the cooling circuit for cooling the switching modules (3, 3', 3") and also inside the housing as insulating medium. - a housing ; - a switching module (3, 3', 3") which is arranged inside the housing and has several switching elements and a cooling boxes with cooling channel enclosed therein, wherein the cooling channels of the various cooling boxes being hydraulically connected to one another via lines ; - an insulating liquid , which surrounds the switching module (3, 3', 3"), inside the housing ; and - a cooling circuit comprising a pump , the cooling channel and a heat exchanger ; - the inside of the housing and the cooling circuit are hydraulically connected to each other in such way that the insulating liquid is used in the cooling circuit for cooling the switching modules (3, 3', 3") and also inside the housing as insulating medium.
A v-clamp , comprising: a band extending circumferentially from a first end to a second end , said band having a first side wall and a second side wall , said first side wall and second side wall establishing a v-angle therebetween in sectional profile; wherein said v-angle has a first value at a first circumferential position of said band and has a second value at a second circumferential position of said band , wherein said first circumferential position resides adjacent a closure mechanism and said second circumferential position resides at a location that is diametrically opposite the closure mechanism, characterized in that said first value being greater than said second value, and a value of said v-angle steadily increases along a circumferential extent of said band from said second circumferential position to said first circumferential position. a band extending circumferentially from a first end to a second end , said band having a first side wall and a second side wall , said first side wall and second side wall establishing a v-angle therebetween in sectional profile; wherein said v-angle has a first value at a first circumferential position of said band and has a second value at a second circumferential position of said band , wherein said first circumferential position resides adjacent a closure mechanism and said second circumferential position resides at a location that is diametrically opposite the closure mechanism, characterized in that said first value being greater than said second value, and a value of said v-angle steadily increases along a circumferential extent of said band from said second circumferential position to said first circumferential position.