A cannulation device for administering an active agent containing composition to an eye comprising: an elongated body with a proximal end and a distal end; a needle with a proximal end, a distal end and a lumen, wherein the proximal end of the needle is fixed to the distal end of the elongated body and the distal end of the needle is bevelled or sharpened for tissue penetration; a flexible cannula comprising an elongated tubular element with a proximal end, a distal end, a lumen and a rounded atraumatic tip to be deployed through the needle; a pathway for transfer of liquid or semi-solid materials from the elongated body to the proximal lumen of the tubular element; and a deployment mechanism coupled to the proximal end of the elongated tubular element to advance the elongated tubular element through the needle; wherein: the elongated tubular element is configured to be illuminated by transmitting light from the proximal portion of the tubular element to the distal tip of the elongated tubular element; and the distal portion of the elongated tubular element is contained in the lumen of the needle prior to deployment of the elongated tubular element; wherein the deployment mechanism comprises a force element configured to apply a deployment force on the elongated tubular element to advance the elongated tubular element through the needle lumen and an actuator to activate the force element. an elongated body with a proximal end and a distal end; a needle with a proximal end, a distal end and a lumen, wherein the proximal end of the needle is fixed to the distal end of the elongated body and the distal end of the needle is bevelled or sharpened for tissue penetration; a flexible cannula comprising an elongated tubular element with a proximal end, a distal end, a lumen and a rounded atraumatic tip to be deployed through the needle; a pathway for transfer of liquid or semi-solid materials from the elongated body to the proximal lumen of the tubular element; and a deployment mechanism coupled to the proximal end of the elongated tubular element to advance the elongated tubular element through the needle; wherein: the elongated tubular element is configured to be illuminated by transmitting light from the proximal portion of the tubular element to the distal tip of the elongated tubular element; and the distal portion of the elongated tubular element is contained in the lumen of the needle prior to deployment of the elongated tubular element; wherein the deployment mechanism comprises a force element configured to apply a deployment force on the elongated tubular element to advance the elongated tubular element through the needle lumen and an actuator to activate the force element. the elongated tubular element is configured to be illuminated by transmitting light from the proximal portion of the tubular element to the distal tip of the elongated tubular element; and the distal portion of the elongated tubular element is contained in the lumen of the needle prior to deployment of the elongated tubular element; wherein the deployment mechanism comprises a force element configured to apply a deployment force on the elongated tubular element to advance the elongated tubular element through the needle lumen and an actuator to activate the force element. <EOS>