mhurhangee/patent-ind-claim-en huggingface dataset:
A method for expanding tumor infiltrating lymphocytes (TILs) into a therapeutic population of TILs comprising: (i) performing a first expansion by culturing a first population of TILs from at least one fine needle aspirate (FNA) or at least one small biopsy from a tumor in a patient in a cell culture medium comprising IL-2 to produce a second population of TILs, wherein the cell culture medium is supplemented with OKT-3 at any one of days 1-3, wherein the first expansion is performed for 3 days to 12 days in order to obtain the second population of TILs, wherein the second population of TILs comprises at least 5 × 10 7 TILs by 3 days to 12 days when the first population of TILs is from a small biopsy; and (ii) performing a second expansion by supplementing the cell culture medium of the second population of TILs with additional IL-2, OKT-3, and antigen presenting cells (APCs), to produce a third population of TILs, wherein the third population of TILs is at least 25-fold greater in number than the second population of TILs, and wherein the second expansion is performed for 3 days to 12 days in order to obtain the third population of TILs, wherein the third population of TILs is a therapeutic population of TILs. (i) performing a first expansion by culturing a first population of TILs from at least one fine needle aspirate (FNA) or at least one small biopsy from a tumor in a patient in a cell culture medium comprising IL-2 to produce a second population of TILs, wherein the cell culture medium is supplemented with OKT-3 at any one of days 1-3, wherein the first expansion is performed for 3 days to 12 days in order to obtain the second population of TILs, wherein the second population of TILs comprises at least 5 × 10 7 TILs by 3 days to 12 days when the first population of TILs is from a small biopsy; and the cell culture medium is supplemented with OKT-3 at any one of days 1-3, wherein the first expansion is performed for 3 days to 12 days in order to obtain the second population of TILs, wherein the second population of TILs comprises at least 5 × 10 7 TILs by 3 days to 12 days when the first population of TILs is from a small biopsy; and (ii) performing a second expansion by supplementing the cell culture medium of the second population of TILs with additional IL-2, OKT-3, and antigen presenting cells (APCs), to produce a third population of TILs, wherein the third population of TILs is at least 25-fold greater in number than the second population of TILs, and wherein the second expansion is performed for 3 days to 12 days in order to obtain the third population of TILs, wherein the third population of TILs is a therapeutic population of TILs.
A method of operation by a wireless communication device that communicates with a wireless communication network and performs radar transmissions for surrounding-environment sensing using a same or overlapping millimeter wave (mmW) frequency range, the method comprising: classifying , for a current orientation and position of the wireless communication device , individual radar beam directions among a plurality of radar beam directions as being restricted or unrestricted, where any given radar beam direction is classified as being restricted based on known or estimated Uplink (UL) reception interference arising in the wireless communication network from radar transmissions by the wireless communication device in the given radar beam direction ; and adapting radar transmissions by the wireless communication device in consideration of the classifications made for the individual radar beam directions , the adapting comprising muting or reducing radar-signal transmission power with respect to each restricted radar beam direction ; and chracterised by the classifying comprising: determining one or more radio network nodes of the wireless communication network to consider, and for each radio network node being considered and each radar beam direction being considered, estimating an UL received power that would be experienced at the considered radio network node for a radar transmission performed by the wireless communication device in the considered radar beam direction at a defined transmit power level. classifying , for a current orientation and position of the wireless communication device , individual radar beam directions among a plurality of radar beam directions as being restricted or unrestricted, where any given radar beam direction is classified as being restricted based on known or estimated Uplink (UL) reception interference arising in the wireless communication network from radar transmissions by the wireless communication device in the given radar beam direction ; and adapting radar transmissions by the wireless communication device in consideration of the classifications made for the individual radar beam directions , the adapting comprising muting or reducing radar-signal transmission power with respect to each restricted radar beam direction ;
Case for cooling of medicines consisting of a bottom part and a lid , characterized in that the bottom part comprises a cooling plate with cooling contact pins , suitable for receiving medicaments in a cooling-contacting manner, which can be arranged in a fixed manner or in a manually variable, stretchable manner, depending on the space requirement, whereby the cooling plate cooperates with a heat exchanger , whereby the cooling contact pins can be arranged with the cooling plate via a conical plug-in connection, whereby an evaporation hollow space is provided between the cooling plate and the heat exchanger .
A system for surgery, comprising: a surgery unit including an operative tip connected to a console; and a foot pedal control in electronic communication with the console, including a base having an undercarriage arranged to lie flat on a ground surface and a treadle mounted for vertical pivoting movement relative to the base, the foot pedal control having a built-in sensor configured to track the pivoting movement of the treadle and to generate an electronic signal for communication to the console and subsequent control of the operative tip , characterized in that the foot pedal control comprises a carrying handle connected to the base and being convertible between at least two positions - a first position above the treadle and generally perpendicular to the undercarriage of the base, and a second position out of the way of the treadle and generally parallel to the undercarriage of the base. a surgery unit including an operative tip connected to a console; and a foot pedal control in electronic communication with the console, including a base having an undercarriage arranged to lie flat on a ground surface and a treadle mounted for vertical pivoting movement relative to the base, the foot pedal control having a built-in sensor configured to track the pivoting movement of the treadle and to generate an electronic signal for communication to the console and subsequent control of the operative tip ,
A solid-bowl screw centrifuge with at least one or more discharge weirs for discharging clarified liquid out of a drum which has a rotational axis (D) and a direction of rotation (K), having the following features: a. at least one or more outlet ports in a drum cover , b. wherein a weir plate , which has a recess , is associated with the at least one outlet port in each case, c. wherein an open discharge channel, by means of which a deflection from a direction parallel to the rotational axis (D) of the drum essentially into a circumferential direction opposite the direction of rotation (K) is carried out, is formed at the outlet opening in the recess , d. wherein the discharge channel is designed in such a way that discharging liquid is directed via the bottom of the discharge channel up to an overflow edge , characterized in that e. the bottom of the discharge channel is inclined inwardly toward the rotational axis (D) toward the overflow edge relative to the tangential direction (T) by an inclination angle δ > 0° at the location of the overflow edge . a. at least one or more outlet ports in a drum cover , b. wherein a weir plate , which has a recess , is associated with the at least one outlet port in each case, c. wherein an open discharge channel, by means of which a deflection from a direction parallel to the rotational axis (D) of the drum essentially into a circumferential direction opposite the direction of rotation (K) is carried out, is formed at the outlet opening in the recess , d. wherein the discharge channel is designed in such a way that discharging liquid is directed via the bottom of the discharge channel up to an overflow edge , characterized in that e. the bottom of the discharge channel is inclined inwardly toward the rotational axis (D) toward the overflow edge relative to the tangential direction (T) by an inclination angle δ > 0° at the location of the overflow edge .
A hybrid module for a drive train of a motor vehicle, comprising an electric machine , a clutch device and a separating clutch , wherein the separating clutch is coupled on the one hand to a dual mass flywheel and on the other hand to an intermediate shaft and has a frictionally engaging package comprising a pressure plate , a counter plate and at least one intermediate plate and clutch discs engaging therebetween, wherein the pressure plate , the intermediate plate and the clutch discs are axially movable, characterized in that an outer disc support is provided which is fixedly connected to the dual mass flywheel , wherein the pressure plate , the intermediate plate and the counter plate are connected in a non-rotatable but detachable manner to the outer disc support , and at least one alignment element is provided, which axially aligns the external toothing, which engages in an axially extending internal toothing of the outer disc support , formed on the pressure plate , the intermediate plate and the counter plate , at least during the insertion of the external toothing into the internal toothing of the outer disc support .
Hydraulic braking device comprising a master cylinder and a brake booster , wherein - a piston of the master cylinder defines a chamber of the master cylinder , said chamber being arranged to contain a pressurized fluid and a control pressure transmitted to one or more vehicle brakes being generated in said chamber; - a piston of the brake booster defines a first and a second pressurized chamber of the brake booster , said chambers being associated to communication means arranged to establish, under rest conditions of the braking device, a communication between the first and the second pressurized chambers of the brake booster and to interrupt such communication during braking; - a control piston (12; 212), driven by actuating a brake pedal, is mounted so as to be tightly slidable in a plunger of the piston of the brake booster , said control piston (12; 212) comprising a first end portion (12a; 212a) having a certain cross-sectional area (A m ) and being arranged to cooperate with a gasket so as to establish, during braking, a modulated communication between the first chamber of the brake booster and a discharge chamber of the master cylinder ; characterized in that it has an effective cross-sectional area (A spool ), counter-acting a pressure existing in a region comprised between the piston of the master cylinder and the control piston , different from said cross-sectional area (A m ) of the first end portion (12a; 212a) of the control piston (12; 212). - a piston of the master cylinder defines a chamber of the master cylinder , said chamber being arranged to contain a pressurized fluid and a control pressure transmitted to one or more vehicle brakes being generated in said chamber; - a piston of the brake booster defines a first and a second pressurized chamber of the brake booster , said chambers being associated to communication means arranged to establish, under rest conditions of the braking device, a communication between the first and the second pressurized chambers of the brake booster and to interrupt such communication during braking; - a control piston (12; 212), driven by actuating a brake pedal, is mounted so as to be tightly slidable in a plunger of the piston of the brake booster , said control piston (12; 212) comprising a first end portion (12a; 212a) having a certain cross-sectional area (A m ) and being arranged to cooperate with a gasket so as to establish, during braking, a modulated communication between the first chamber of the brake booster and a discharge chamber of the master cylinder ; characterized in that it has an effective cross-sectional area (A spool ), counter-acting a pressure existing in a region comprised between the piston of the master cylinder and the control piston , different from said cross-sectional area (A m ) of the first end portion (12a; 212a) of the control piston (12; 212).
A method, comprising: determining , based on input to one or more microphones of a mobile computing device , that a user has provided a spoken utterance , wherein the mobile computing device includes one or more first motors that maneuver the mobile computing device across an area ; determining , based on the input to the one or more microphones, that the user is requesting the mobile computing device to perform an action that is associated with an automated assistant rendering content via one or more speakers and/or a display panel of the mobile computing device; determining, based on the input to the one or more microphones, an additional input to the one or more microphones, and/or one or more other sensors of the mobile computing device, a location of the user relative to the mobile computing device; characterised by : in response to determining that the user has requested graphical content to be rendered at the mobile computing device and determining that the location of the user is not within a distance for perceiving the graphical content: causing the first motor of the mobile computing device to maneuver the mobile computing device toward the location of the user, subsequently, when the location of the user is within the distance for perceiving the graphical content, causing one or more one or more second motors of the mobile computing device to maneuver the display panel of the mobile computing device in furtherance of rendering the graphical content toward the user, and causing the display panel to render the graphical content in furtherance of performing the action. determining , based on input to one or more microphones of a mobile computing device , that a user has provided a spoken utterance , wherein the mobile computing device includes one or more first motors that maneuver the mobile computing device across an area ; determining , based on the input to the one or more microphones, that the user is requesting the mobile computing device to perform an action that is associated with an automated assistant rendering content via one or more speakers and/or a display panel of the mobile computing device; determining, based on the input to the one or more microphones, an additional input to the one or more microphones, and/or one or more other sensors of the mobile computing device, a location of the user relative to the mobile computing device; causing the first motor of the mobile computing device to maneuver the mobile computing device toward the location of the user, subsequently, when the location of the user is within the distance for perceiving the graphical content, causing one or more one or more second motors of the mobile computing device to maneuver the display panel of the mobile computing device in furtherance of rendering the graphical content toward the user, and causing the display panel to render the graphical content in furtherance of performing the action.
A motor , comprising: a first connection terminal comprising a circuit board , wherein the circuit board comprises a coil circuit ; a second connection terminal comprising a permanent magnet , wherein the permanent magnet is adjacent to the coil circuit , wherein there is a gap between the permanent magnet and the coil circuit , and the permanent magnet has an axial magnetization structure; and a lens module ; wherein one of the first connection terminal and the second connection terminal is a rotator, and wherein the other of the first connection terminal and the second connection terminal is a stator, characterized in that the rotator is fixedly connected to the lens module and sleeved over the lens module , and the stator is movably connected to the lens module and sleeved over the lens module . a first connection terminal comprising a circuit board , wherein the circuit board comprises a coil circuit ; a second connection terminal comprising a permanent magnet , wherein the permanent magnet is adjacent to the coil circuit , wherein there is a gap between the permanent magnet and the coil circuit , and the permanent magnet has an axial magnetization structure; and a lens module ; wherein one of the first connection terminal and the second connection terminal is a rotator, and wherein the other of the first connection terminal and the second connection terminal is a stator, characterized in that the rotator is fixedly connected to the lens module and sleeved over the lens module , and the stator is movably connected to the lens module and sleeved over the lens module .
A control method for a power supply apparatus comprising a first battery pack , a second battery pack , and a direct current converter , the control method being applicable to a battery management system BMS of a vehicle, and comprising: controlling (S410), under a condition that the vehicle is in a parking state, the first battery pack to supply power to a first load of the vehicle, and controlling the first battery pack and the second battery pack to stop supplying power to a second load of the vehicle; acquiring (S420), in a process of supplying power to the first load , a capacity parameter of the first battery pack ; controlling (S430), under a condition that the capacity parameter of the first battery pack is lower than a first preset capacity threshold, the direct current converter to transmit electric energy of the second battery pack to the first battery pack . controlling (S410), under a condition that the vehicle is in a parking state, the first battery pack to supply power to a first load of the vehicle, and controlling the first battery pack and the second battery pack to stop supplying power to a second load of the vehicle; acquiring (S420), in a process of supplying power to the first load , a capacity parameter of the first battery pack ; controlling (S430), under a condition that the capacity parameter of the first battery pack is lower than a first preset capacity threshold, the direct current converter to transmit electric energy of the second battery pack to the first battery pack .
A rear-view mirror assembly of a vehicle, which vehicle comprises an onboard air-conditioner, the rear-view mirror assembly comprising a rear-view mirror , a laser radar , and an air supply pipe , wherein the rear-view mirror is provided with a chamber, the laser radar is disposed in the chamber and a detection part of the laser radar is exposed to the outside of the rear-view mirror , an inlet of the air supply pipe is in communication with an air outlet of the onboard air-conditioner, wherein the air supply pipe extends into the chamber, and an outlet of the air supply pipe is arranged towards the laser radar, wherein the rear-view mirror assembly further comprises a snap-fit assembly disposed in the chamber, the air supply pipe being connected inside the chamber through the snap-fit assembly; and wherein the snap-fit assembly comprises a plurality of snap-fit members , the plurality of snap-fit members being arranged at intervals from one another and clamping the air supply pipe in the chamber. wherein the air supply pipe extends into the chamber, and an outlet of the air supply pipe is arranged towards the laser radar, wherein the rear-view mirror assembly further comprises a snap-fit assembly disposed in the chamber, the air supply pipe being connected inside the chamber through the snap-fit assembly; and wherein the snap-fit assembly comprises a plurality of snap-fit members , the plurality of snap-fit members being arranged at intervals from one another and clamping the air supply pipe in the chamber.
An imaging plan presentation apparatus comprising: an imaging condition acquisition unit that is configured to acquire an imaging condition necessary for detection of damage to a structure; an imaging plan generation unit that is configured to generate an imaging plan including a set of imaging ranges to cover an entirety of each check point for the structure on the basis of the imaging condition acquired by the imaging condition acquisition unit; an imaging plan presentation unit that is configured to present the imaging plan to a user; wherein the imaging plan presentation apparatus is characterized by further comprising an imaging plan update unit that is configured to update the imaging plan on the basis of an uncaptured imaging range identified on the basis of the imaging plan generated by the imaging plan generation unit and image data obtained by capturing the imaging range of each check point for the structure and to re-generate an imaging plan corresponding to the uncaptured imaging range, wherein the imaging plan presentation unit is configured to present the imaging plan re-generated by the imaging plan update unit to the user. an imaging condition acquisition unit that is configured to acquire an imaging condition necessary for detection of damage to a structure; an imaging plan generation unit that is configured to generate an imaging plan including a set of imaging ranges to cover an entirety of each check point for the structure on the basis of the imaging condition acquired by the imaging condition acquisition unit; an imaging plan presentation unit that is configured to present the imaging plan to a user; wherein the imaging plan presentation apparatus is characterized by further comprising an imaging plan update unit that is configured to update the imaging plan on the basis of an uncaptured imaging range identified on the basis of the imaging plan generated by the imaging plan generation unit and image data obtained by capturing the imaging range of each check point for the structure and to re-generate an imaging plan corresponding to the uncaptured imaging range, wherein the imaging plan presentation unit is configured to present the imaging plan re-generated by the imaging plan update unit to the user.