A kit for screening a compound for enzyme inhibition activity, the kit comprising: a first multiwell plate 150 having a plurality of enzymes disposed within a first plurality of wells; a second multiwell plate 160 having a plurality of enzyme substrates disposed within a second plurality of wells, wherein the order in which the enzymes are disposed on the first plate is determined by the order in which the corresponding enzyme substrates are disposed on the second plate; a phosphate source 162 disposed within each well of the second plate, the phosphate source disposed in the well at a concentration specific for the enzyme disposed in the corresponding well of the first plate; and a cofactor 164 disposed within each well of the second plate, the cofactor disposed in each well at a concentration specific for the enzyme disposed in the corresponding well of the first plate, characterised in that the first plurality of wells of the first multiwell plate are disposed evenly upon the plate in 24 columns 250, each column including a different enzyme disposed within the wells of the column wherein: (i) the order in which the enzymes are disposed on the first plate from column 1 to column 24 is MAPKAPK2, AurA, PKCζ, RSK1, MAPKAPK5, Erk1, PKD2, CK1δ, CHK1, ABL, FYN, LYNa, CHK2, MET, LCK, SRC, GSK3β, Erk2, PKACα, AKT2, INSR, p38α, AKT1, and MSK1; or (ii) the order in which the enzymes are disposed on the first plate from column 1 to column 24 is PKCβ2, ROCK2, CDK2, MST2, PKG1α, PAK2, IGF1R, FGFR1, MARK1, CAMK2δ, PIM2, BTK, c-TAK1, DYRKIa, CaMK4, FLT3, HGK, KDR, Raf-1, P70S6K, IRAK4, SGK, and SYK. a first multiwell plate 150 having a plurality of enzymes disposed within a first plurality of wells; a second multiwell plate 160 having a plurality of enzyme substrates disposed within a second plurality of wells, wherein the order in which the enzymes are disposed on the first plate is determined by the order in which the corresponding enzyme substrates are disposed on the second plate; a phosphate source 162 disposed within each well of the second plate, the phosphate source disposed in the well at a concentration specific for the enzyme disposed in the corresponding well of the first plate; and a cofactor 164 disposed within each well of the second plate, the cofactor disposed in each well at a concentration specific for the enzyme disposed in the corresponding well of the first plate, characterised in that the first plurality of wells of the first multiwell plate are disposed evenly upon the plate in 24 columns 250, each column including a different enzyme disposed within the wells of the column wherein: (i) the order in which the enzymes are disposed on the first plate from column 1 to column 24 is MAPKAPK2, AurA, PKCζ, RSK1, MAPKAPK5, Erk1, PKD2, CK1δ, CHK1, ABL, FYN, LYNa, CHK2, MET, LCK, SRC, GSK3β, Erk2, PKACα, AKT2, INSR, p38α, AKT1, and MSK1; or (ii) the order in which the enzymes are disposed on the first plate from column 1 to column 24 is PKCβ2, ROCK2, CDK2, MST2, PKG1α, PAK2, IGF1R, FGFR1, MARK1, CAMK2δ, PIM2, BTK, c-TAK1, DYRKIa, CaMK4, FLT3, HGK, KDR, Raf-1, P70S6K, IRAK4, SGK, and SYK. (i) the order in which the enzymes are disposed on the first plate from column 1 to column 24 is MAPKAPK2, AurA, PKCζ, RSK1, MAPKAPK5, Erk1, PKD2, CK1δ, CHK1, ABL, FYN, LYNa, CHK2, MET, LCK, SRC, GSK3β, Erk2, PKACα, AKT2, INSR, p38α, AKT1, and MSK1; or (ii) the order in which the enzymes are disposed on the first plate from column 1 to column 24 is PKCβ2, ROCK2, CDK2, MST2, PKG1α, PAK2, IGF1R, FGFR1, MARK1, CAMK2δ, PIM2, BTK, c-TAK1, DYRKIa, CaMK4, FLT3, HGK, KDR, Raf-1, P70S6K, IRAK4, SGK, and SYK. <EOS>