mhurhangee/patent-ind-claim-en huggingface dataset:
A method of making a stiffened composite structure , comprising: fabricating a first fiber preform ; placing the first fiber preform in a mold recess having the geometry of a stiffener ; placing a second fiber preform over the mold recess covering the first preform ; co-infusing the first and second fiber preforms with a polymer resin; and curing the resin-infused preforms, wherein fabricating the first fiber preform includes braiding fibers into a flexible tubular shell , and filling the shell with continuous unidirectional fibers, and placing the first fiber preform in the mold recess includes conforming the tubular shell to the geometry of the recess . fabricating a first fiber preform ; placing the first fiber preform in a mold recess having the geometry of a stiffener ; placing a second fiber preform over the mold recess covering the first preform ; co-infusing the first and second fiber preforms with a polymer resin; and curing the resin-infused preforms, wherein fabricating the first fiber preform includes braiding fibers into a flexible tubular shell , and filling the shell with continuous unidirectional fibers, and placing the first fiber preform in the mold recess includes conforming the tubular shell to the geometry of the recess .
A topical formulation composition comprising one or more UV absorbing conjugate compounds comprising a UV absorbing compound conjugated with a conjugate compound, wherein the a UV absorbing compound is selected from a group consisting of a benzophenone compound conjugated to a conjugate compound via a sulfonamide linker wherein the benzophenone conjugate compound has a molecular weight of at least 800 daltons; a benzimidazole compound conjugated to a conjugate compound via a sulfonamide linker wherein the benzimidazole conjugate compound has a molecular weight of at least 800 daltons; a benzotriazole compound conjugated to a conjugate compound via an amide linker wherein the benzotriazole conjugate compound has a molecular weight of at least 800 daltons; a benzotriazole compound conjugated to a conjugate compound through the product of a Michael addition reaction wherein the benzotriazole conjugate compound has a molecular weight of at least 800 daltons; a benzotriazole functionalized polymer wherein benzotriazole functionalized polymer has a molecular weight of at least 800 daltons and wherein the benzotriazole is bonded to the polymer as a methacrylate, acrylate or acrylamide derivative of a benzotriazole compound; and a benzotriazole compound conjugated to a polysaccharide wherein the benzotriazole polysaccharide conjugate compound has a molecular weight of at least 800 daltons, wherein the UV absorbing conjugate compound is not transported or absorbed through the skin.
An in vitro method for quantitative determination of the expression of Programmed Death Ligand 1 ( PD-L1 ) in a liquid biopsy sample of Circulating Tumor Cells (CTC), said method comprising the steps: i. subjecting the liquid biopsy sample to reverse transcription using RNA present in the sample as a template in order to synthesize a corresponding cDNA sequence, ii. forming a reaction mixture comprising the sample, nucleic acid amplification reagents, a target primer pair, a target hydrolysis probe, said target primer pair and target hydrolysis probe being capable of hybridizing to PD-L1 mRNA, and said target primer pair consisting of a forward target primer comprising the sequence 5'-GCTGAATTGGTCATCCCAGAA-3' (SEQ ID NO: 4) and a reverse target primer comprising the sequence 5'-TTTCACATCCATCATTCTCCCTT-3' (SEQ ID NO: 6) iii. subjecting the reaction mixture to amplification conditions optimized to generate at least one copy of a nucleic acid sequence complementary to a target sequence, said target sequence being a mRNA transcript of the PD-L1 mRNA sequence (SEQ ID NO: 1), and iv. determining the amount of PD-L1 mRNA in the liquid biopsy sample, v. normalizing the expression of PD-L1 with respect to an expression of a reference gene whose expression levels remain constant between different cell types, vi. comparing the amount of PD-L1 mRNA expressed in the said sample to a positive control which is a sample comprising PD-L1 mRNA and a negative control which is a sample without comprising PD-L1 mRNA in order to estimate an overexpression of the PD-L1 mRNA sequence. i. subjecting the liquid biopsy sample to reverse transcription using RNA present in the sample as a template in order to synthesize a corresponding cDNA sequence, ii. forming a reaction mixture comprising the sample, nucleic acid amplification reagents, a target primer pair, a target hydrolysis probe, said target primer pair and target hydrolysis probe being capable of hybridizing to PD-L1 mRNA, and said target primer pair consisting of a forward target primer comprising the sequence 5'-GCTGAATTGGTCATCCCAGAA-3' (SEQ ID NO: 4) and a reverse target primer comprising the sequence 5'-TTTCACATCCATCATTCTCCCTT-3' (SEQ ID NO: 6) iii. subjecting the reaction mixture to amplification conditions optimized to generate at least one copy of a nucleic acid sequence complementary to a target sequence, said target sequence being a mRNA transcript of the PD-L1 mRNA sequence (SEQ ID NO: 1), and iv. determining the amount of PD-L1 mRNA in the liquid biopsy sample, v. normalizing the expression of PD-L1 with respect to an expression of a reference gene whose expression levels remain constant between different cell types, vi. comparing the amount of PD-L1 mRNA expressed in the said sample to a positive control which is a sample comprising PD-L1 mRNA and a negative control which is a sample without comprising PD-L1 mRNA in order to estimate an overexpression of the PD-L1 mRNA sequence.
A sensor for determining a process variable in a container , the sensor comprising a housing and a process connection , the housing being rotatably arranged in the process connection in a connecting region , with the housing comprising a circumferential first groove on its outer circumference and the process connection comprising a circumferential second groove on its inner circumference, wherein the two grooves are arranged at a same height and thus merge radially into one another, and a fixing element is arranged in the cavity formed by the two grooves , characterized in that the fixing element is either originally inserted into the second groove and then displaced inwards to achieve an assembled position, or is originally inserted into the first groove and then pulled outwards to achieve an assembled position, wherein, in the assembled position, the fixing element is located with a respective radial portion both in the first groove and in the second groove , and in that there is at least one radial screw for displacing or pulling the fixing element from its original position. characterized in that the fixing element is either originally inserted into the second groove and then displaced inwards to achieve an assembled position, or is originally inserted into the first groove and then pulled outwards to achieve an assembled position, wherein, in the assembled position, the fixing element is located with a respective radial portion both in the first groove and in the second groove , and in that there is at least one radial screw for displacing or pulling the fixing element from its original position.
A system for aligning a patient interface for use in delivering a flow of a breathing gas to the airway of a patient, the system comprising: a primary adhesive arrangement structured to secure the patient interface to the patient, and a base structured to be disposed on a surface, the base comprising a central member protruding upward from the base to a contoured surface , the central member including a pair of protruding alignment elements extending further upward from the contoured surface, wherein the primary adhesive arrangement comprises a pair of first apertures which are adapted to be positioned such that the pair of protruding alignment elements of the base extend through the pair of first apertures; characterized in that the system comprises a secondary adhesive arrangement comprising a pair of second apertures which are adapted to be positioned such that the pair of protruding alignment elements of the base extend through the pair of second apertures; and the patient interface comprises a pair of nasal apertures which are adapted to be positioned such that the pair of protruding alignment elements of the base extend through the pair of nasal apertures. the primary adhesive arrangement comprises a pair of first apertures which are adapted to be positioned such that the pair of protruding alignment elements of the base extend through the pair of first apertures; characterized in that the system comprises a secondary adhesive arrangement comprising a pair of second apertures which are adapted to be positioned such that the pair of protruding alignment elements of the base extend through the pair of second apertures; and the patient interface comprises a pair of nasal apertures which are adapted to be positioned such that the pair of protruding alignment elements of the base extend through the pair of nasal apertures.
Method for loading a bicycle carrier detachably attached to the trailer coupling of a motor vehicle with at least one bicycle, wherein the bicycle carrier has a frame which is designed to be pivotable by means of a lever mechanism supported by at least one gas pressure spring in relation to a coupling device present on the bicycle carrier between a transport position and a loading position, characterized by the following method steps: - releasable fixing of a trolley equipped with wheels or rollers underneath the bicycle carrier , - approximation of the bicycle carrier with the transport carriage to the trailer coupling of the motor vehicle, - adjustment of the coupling device to a height level corresponding to the trailer coupling, so that the coupling device with its coupling opening directly receives the trailer coupling by horizontal movement of the bicycle carrier connected to the transport carriage , - fixing the bicycle carrier to the trailer coupling by means of an existing clamping and/or screwing mechanism , - release and remove the trolley from the bicycle carrier , - lowering the frame to the ground using the lever mechanism , - sliding the at least one bicycle into the at least one wheel holder provided for this purpose on the bicycle carrier and fixing the bicycle in or on the bicycle carrier , - lifting the frame of the bicycle carrier into the transport position by means of the existing lever mechanism . - releasable fixing of a trolley equipped with wheels or rollers underneath the bicycle carrier , - approximation of the bicycle carrier with the transport carriage to the trailer coupling of the motor vehicle, - adjustment of the coupling device to a height level corresponding to the trailer coupling, so that the coupling device with its coupling opening directly receives the trailer coupling by horizontal movement of the bicycle carrier connected to the transport carriage , - fixing the bicycle carrier to the trailer coupling by means of an existing clamping and/or screwing mechanism , - release and remove the trolley from the bicycle carrier , - lowering the frame to the ground using the lever mechanism , - sliding the at least one bicycle into the at least one wheel holder provided for this purpose on the bicycle carrier and fixing the bicycle in or on the bicycle carrier , - lifting the frame of the bicycle carrier into the transport position by means of the existing lever mechanism .
A radio communication system supporting dual connectivity, wherein the radio communication system comprises a user device , a master node and a secondary node , wherein the master node and the secondary node are simultaneously connected to the user device, wherein the user device comprises: a radio communication unit configured to receive a measurement configuration from each of the master node and the secondary node; and a measuring unit configured to measure reception quality of a target cell based on the measurement configuration received from each of the master node and the secondary node, and the master node comprises a radio communication unit configured to transmit a measurement configuration to the user device, the secondary node comprises a radio communication unit configured to transmit a measurement configuration to the user device, the master node comprises a measurement controlling unit configured to share information on a number of carrier frequencies to be measured by the user device with the secondary node, and the master node and the secondary node are configured to adjust a number of carrier frequencies to be measured by the user device such that said number does not exceed the number of measurements of carrier frequencies of the target cell that the user device can perform simultaneously based on the shared information. the user device comprises: a radio communication unit configured to receive a measurement configuration from each of the master node and the secondary node; and a measuring unit configured to measure reception quality of a target cell based on the measurement configuration received from each of the master node and the secondary node, and a radio communication unit configured to receive a measurement configuration from each of the master node and the secondary node; and a measuring unit configured to measure reception quality of a target cell based on the measurement configuration received from each of the master node and the secondary node, and the master node comprises a radio communication unit configured to transmit a measurement configuration to the user device, the secondary node comprises a radio communication unit configured to transmit a measurement configuration to the user device, the master node comprises a measurement controlling unit configured to share information on a number of carrier frequencies to be measured by the user device with the secondary node, and the master node and the secondary node are configured to adjust a number of carrier frequencies to be measured by the user device such that said number does not exceed the number of measurements of carrier frequencies of the target cell that the user device can perform simultaneously based on the shared information.
A track shoe comprising: a one-piece track shoe body including a first set of pin lugs , a second set of pin lugs , and a roller pad positioned between the first set of pin lugs and the second set of pin lugs ; the roller pad including a roller contact surface extending in a fore-to-aft direction between a first roller pad end and a second roller pad end ; and the first roller pad end including a relatively softer material , and the second roller pad end including a relatively harder material that forms a trimming edge for trimming off interfering material of an adjacent track shoe in a machine track . a one-piece track shoe body including a first set of pin lugs , a second set of pin lugs , and a roller pad positioned between the first set of pin lugs and the second set of pin lugs ; the roller pad including a roller contact surface extending in a fore-to-aft direction between a first roller pad end and a second roller pad end ; and the first roller pad end including a relatively softer material , and the second roller pad end including a relatively harder material that forms a trimming edge for trimming off interfering material of an adjacent track shoe in a machine track .
A communication method, comprising: performing (S901, S1301), by a plurality of first antennas of a network device, listen before talk LBT on a first carrier, and determining, by the network device, a first time offset when at least one first antenna completes the LBT, wherein the plurality of first antennas are configured to send, on the first carrier, synchronization signal blocks SSBs of a first synchronization signal burst set SS Burst Set, and the first time offset is a time offset of an actual transmission time of the first SS Burst Set on the first carrier relative to a configured transmission time of the first SS Burst Set; and sending (S902, S1302), by the network device, the first time offset to a terminal; sending (S1303), by the network device, first indication information to the terminal, wherein the first indication information is used to indicate whether the plurality of first antennas separately complete the LBT when sending the SSBs of the first SS Burst Set, or the first indication information is used to indicate whether the SSBs of the first SS Burst Set are successfully sent. performing (S901, S1301), by a plurality of first antennas of a network device, listen before talk LBT on a first carrier, and determining, by the network device, a first time offset when at least one first antenna completes the LBT, wherein the plurality of first antennas are configured to send, on the first carrier, synchronization signal blocks SSBs of a first synchronization signal burst set SS Burst Set, and the first time offset is a time offset of an actual transmission time of the first SS Burst Set on the first carrier relative to a configured transmission time of the first SS Burst Set; and sending (S902, S1302), by the network device, the first time offset to a terminal; sending (S1303), by the network device, first indication information to the terminal, wherein the first indication information is used to indicate whether the plurality of first antennas separately complete the LBT when sending the SSBs of the first SS Burst Set, or the first indication information is used to indicate whether the SSBs of the first SS Burst Set are successfully sent.
A communication apparatus comprising: a circuitry operative to determine respective priorities of a plurality of target receivers to which data are transmitted, and to assign power for transmitting the data at least according to a power loss feature related to a particular target receiver of which the priority is the highest; and a transmitter operative to transmit, to the plurality of target receivers, the data with the assigned power; wherein data are transmitted to the plurality of target receivers simultaneously in a subframe including a plurality of resource blocks allocated to each target receiving unit. a circuitry operative to determine respective priorities of a plurality of target receivers to which data are transmitted, and to assign power for transmitting the data at least according to a power loss feature related to a particular target receiver of which the priority is the highest; and a transmitter operative to transmit, to the plurality of target receivers, the data with the assigned power; wherein data are transmitted to the plurality of target receivers simultaneously in a subframe including a plurality of resource blocks allocated to each target receiving unit.
A current detector capable of measuring a current circulating in an electrical conductor , the current detector including: - a probe including: - a converter capable of converting the magnetic field induced by the current to be measured in the conductor into a voltage, the converter being a magnetostrictive and piezoelectric composite material, and - a circuit for detecting the voltage converted by the converter , the probe further including an excitation winding arranged to generate a modulating magnetic field in the converter , the detection circuit including a unit for demodulating the voltage converted by the converter , the current detector being characterised by the converter having an electric voltage-magnetic field feature including a linear portion, the converter being capable of converting the magnetic field induced by the current to be measured in the linear portion of the electric voltage-magnetic field feature. - a probe including: - a converter capable of converting the magnetic field induced by the current to be measured in the conductor into a voltage, the converter being a magnetostrictive and piezoelectric composite material, and - a converter capable of converting the magnetic field induced by the current to be measured in the conductor into a voltage, the converter being a magnetostrictive and piezoelectric composite material, and - a circuit for detecting the voltage converted by the converter , the probe further including an excitation winding arranged to generate a modulating magnetic field in the converter , the detection circuit including a unit for demodulating the voltage converted by the converter , the current detector being characterised by the converter having an electric voltage-magnetic field feature including a linear portion, the converter being capable of converting the magnetic field induced by the current to be measured in the linear portion of the electric voltage-magnetic field feature.
Gear unit housing for a gear unit having a two-sided control lever for moving two switch contacts of a circuit breaker in opposite directions to one another, the gear unit housing comprising - a housing cassette with a housing base , - a cover plate that is connected in a detachable manner to the housing cassette by means of screw connections and lies opposite the housing base , - a bearing shaft that is connected to the housing cassette and the cover plate and extends between the housing base and the cover plate for mounting the control lever in such a manner that said control lever is able to rotate about the bearing shaft , characterized by at least one spigot element that connects the housing cassette and the cover plate in a positive-locking manner. - a housing cassette with a housing base , - a cover plate that is connected in a detachable manner to the housing cassette by means of screw connections and lies opposite the housing base , - a bearing shaft that is connected to the housing cassette and the cover plate and extends between the housing base and the cover plate for mounting the control lever in such a manner that said control lever is able to rotate about the bearing shaft ,
A pharmaceutical composition for use as a medicament, wherein the pharmaceutical composition is orally administered, and wherein the pharmaceutical composition comprises a superoxide dismutase produced by a Bacillus amyloliquefaciens GF423 strain which has been internationally deposited with the Korean Collection for Type Culture (KCTC) under accession number KCTC 13222BP, wherein the superoxide dismutase comprises an amino acid sequence of SEQ ID NO: 2. the pharmaceutical composition is orally administered, and wherein the pharmaceutical composition comprises a superoxide dismutase produced by a Bacillus amyloliquefaciens GF423 strain which has been internationally deposited with the Korean Collection for Type Culture (KCTC) under accession number KCTC 13222BP, wherein the superoxide dismutase comprises an amino acid sequence of SEQ ID NO: 2.