mhurhangee/patent-ind-claim-en huggingface dataset:
A method for determining a cellular function of an active NFkB cellular signaling pathway in a cell sample containing cells with an active NFkB cellular signaling pathway, the method comprising: determining the expression level of two or more genes selected from the group 1 consisting of BCL2, BCL2L1, CCND2, SKP2, CSF1, NOX1 and SERPINE2; and determining the expression level of two genes selected from group 2 consisting of CYP27B1, IGHE/IGHG1; and determining the expression level of two or more genes selected from group 3 consisting of BIRC3, CCL2, GZMB, SOD2, CCL5 and MMP1, and determining the cellular function based on expression levels of the selected genes of groups 1, 2 and 3, wherein the cellular function is determined by differential expression analysis of the expression levels of the selected genes of groups 1, 2 and 3, wherein the cellular function is determined to be cell division if the genes selected from group 1 are differentially expressed, wherein the cellular function is determined to be apoptosis if the genes selected from group 2 are differentially expressed, and/or wherein the cellular function is determined to be protection against oxidative stress if the genes selected from group 3 are differentially expressed. determining the expression level of two or more genes selected from the group 1 consisting of BCL2, BCL2L1, CCND2, SKP2, CSF1, NOX1 and SERPINE2; and determining the expression level of two genes selected from group 2 consisting of CYP27B1, IGHE/IGHG1; and determining the expression level of two or more genes selected from group 3 consisting of BIRC3, CCL2, GZMB, SOD2, CCL5 and MMP1, and determining the cellular function based on expression levels of the selected genes of groups 1, 2 and 3, wherein the cellular function is determined by differential expression analysis of the expression levels of the selected genes of groups 1, 2 and 3, wherein the cellular function is determined to be cell division if the genes selected from group 1 are differentially expressed, wherein the cellular function is determined to be apoptosis if the genes selected from group 2 are differentially expressed, and/or wherein the cellular function is determined to be protection against oxidative stress if the genes selected from group 3 are differentially expressed.
A porous fibre material, containing or consisting of: - at least 50% of vegetable fibres, in particular cellulose fibres, in relation to the total weight of the material, - at least one layer of silicate compound impregnated in and/or between the fibres, - said at least one layer of silicate compound being in association with at least one multivalent cation which association reinforces the fibre system by forming an interconnected network, - less than 10% by weight of zincate or aluminate based on the silicate compound, provided that: • said at least one multivalent cation, in association with the silicate compound, compensates at least 10% of the negative charge carried by the silicate compound. - at least 50% of vegetable fibres, in particular cellulose fibres, in relation to the total weight of the material, - at least one layer of silicate compound impregnated in and/or between the fibres, - said at least one layer of silicate compound being in association with at least one multivalent cation which association reinforces the fibre system by forming an interconnected network, - less than 10% by weight of zincate or aluminate based on the silicate compound, • said at least one multivalent cation, in association with the silicate compound, compensates at least 10% of the negative charge carried by the silicate compound.
Secondary electrochemical cell having the features a. the cell comprises a positive electrode which is able to incorporate and release lithium reversibly, b. the cell comprises a negative electrode which is able to incorporate and release lithium reversibly, c. the cell comprises, in the electrodes, mobile lithium which is available for incorporation and release processes in the electrodes, d. the cell comprises an electrolyte via which the mobile lithium can migrate back and forth in the form of ions between the positive and the negative electrode, e. the cell comprises a housing which encloses an interior space in which the electrodes and the electrolyte are arranged, f. the cell comprises, in addition to the lithium present in the electrodes, a lithium depot in order to be able to compensate for lithium losses during formation of the cell and/or during operation, g. the cell is a button cell and h. the lithium depot is a lithium alloy composed of lithium and at least one alloying partner, characterized in that the proportion of lithium in the lithium alloy is in the range from 5% by weight to 46% by weight. a. the cell comprises a positive electrode which is able to incorporate and release lithium reversibly, b. the cell comprises a negative electrode which is able to incorporate and release lithium reversibly, c. the cell comprises, in the electrodes, mobile lithium which is available for incorporation and release processes in the electrodes, d. the cell comprises an electrolyte via which the mobile lithium can migrate back and forth in the form of ions between the positive and the negative electrode, e. the cell comprises a housing which encloses an interior space in which the electrodes and the electrolyte are arranged, f. the cell comprises, in addition to the lithium present in the electrodes, a lithium depot in order to be able to compensate for lithium losses during formation of the cell and/or during operation, g. the cell is a button cell and h. the lithium depot is a lithium alloy composed of lithium and at least one alloying partner, characterized in that the proportion of lithium in the lithium alloy is in the range from 5% by weight to 46% by weight.
A battery module with a stack of flat battery cells, and a mounting for the battery cells, wherein each of the battery cells has a contact tab , which is led through the mounting to a head side of the battery module, and wherein the contact tabs are connected to each other on the head side at a junction , characterised in that , the contact tabs , are routed from the battery cells to the junction , such that, at least in some sections, they move away from the junction .
A method of calculating a level of similarity of a first piece of data from a first party to a second piece of data from a second party without revealing the first and second pieces of data themselves, the method comprising: The first party creates a first fingerprint from a first piece of data, wherein the first fingerprint is a bit string that represents one of more properties associated with the first piece of data; The second party creates a second fingerprint from a second piece of data, wherein the second fingerprint is a bit string that represents one of more properties associated with the second piece of data; The first party generates a set of GM keys with associated public keys and private keys; The first party encrypts the first fingerprint with the public keys to create an encrypted first fingerprint; The first party sends the public keys to the second party; The second party encrypts the second fingerprint with the public keys to create an encrypted second fingerprint; The first party sends the encrypted first fingerprint to the second party; The second party performs an XOR operation on the encrypted first fingerprint and the encrypted second fingerprint, thereby creating an encrypted fingerprint XOR; The second party scrambles the encrypted fingerprint XOR, thereby creating a scrambled encrypted fingerprint XOR; The second party sends the scrambled encrypted fingerprint XOR to the first party; The first party decrypts the scrambled encrypted fingerprint XOR using the private keys, and counts the number of bits in the scrambled fingerprint XOR, thereby learning the level of similarity between the first and second fingerprints. The first party creates a first fingerprint from a first piece of data, wherein the first fingerprint is a bit string that represents one of more properties associated with the first piece of data; The second party creates a second fingerprint from a second piece of data, wherein the second fingerprint is a bit string that represents one of more properties associated with the second piece of data; The first party generates a set of GM keys with associated public keys and private keys; The first party encrypts the first fingerprint with the public keys to create an encrypted first fingerprint; The first party sends the public keys to the second party; The second party encrypts the second fingerprint with the public keys to create an encrypted second fingerprint; The first party sends the encrypted first fingerprint to the second party; The second party performs an XOR operation on the encrypted first fingerprint and the encrypted second fingerprint, thereby creating an encrypted fingerprint XOR; The second party scrambles the encrypted fingerprint XOR, thereby creating a scrambled encrypted fingerprint XOR; The second party sends the scrambled encrypted fingerprint XOR to the first party; The first party decrypts the scrambled encrypted fingerprint XOR using the private keys, and counts the number of bits in the scrambled fingerprint XOR, thereby learning the level of similarity between the first and second fingerprints.
A printed circuit board comprising; an insulating layer ; a pad formed on the insulating layer ; a solder resist disposed on the insulating layer and the pad and having an opening section exposing an upper surface of the pad ; a bump connection section disposed on the pad and filling the opening section of the solder resist , and protruded from an upper surface of the solder resist ; a plating seed layer disposed between an inner wall of the solder resist and a side surface of the bump connection section ; a bump disposed on the bump connection section and having a narrower width than the opening section of the solder resist ; and a solder disposed on the bump and having the same width as the width of the bump , wherein the bump connection section comprises a first portion on the pad and filling the opening section of the solder resist , and protruded from an upper surface of the solder resist , and a second portion on the first portion, wherein the upper surface of the first portion has a larger width than the lower surface of the second portion.
An information processing apparatus comprising: an image processing unit configured to generate a display image including a game image; a distribution processing unit configured to distribute the display image to one or more of information processing terminals through a shared server ; a participation processing unit configured to accept play requests of viewing users operating the information processing terminals and to approve a game play of one of the viewing users who has made a request for a play; and an application execution unit configured to process a game using operation information transmitted from the information processing terminal operated by the viewing user the game play of which has been approved, wherein the participation processing unit counts the number of play requests which have been accepted, and the image processing unit includes the counted number of the play requests in the display image, wherein the participation processing unit is configured to approve the game play of one of the viewing users who has made a request for a play based on a predetermined criterion, wherein the participation processing unit is configured to automatically select the viewing user who has the highest skill level or who is the first person expressing his intention to participate in the game. an image processing unit configured to generate a display image including a game image; a distribution processing unit configured to distribute the display image to one or more of information processing terminals through a shared server ; a participation processing unit configured to accept play requests of viewing users operating the information processing terminals and to approve a game play of one of the viewing users who has made a request for a play; and an application execution unit configured to process a game using operation information transmitted from the information processing terminal operated by the viewing user the game play of which has been approved, wherein the participation processing unit counts the number of play requests which have been accepted, and the image processing unit includes the counted number of the play requests in the display image, wherein the participation processing unit is configured to approve the game play of one of the viewing users who has made a request for a play based on a predetermined criterion, wherein the participation processing unit is configured to automatically select the viewing user who has the highest skill level or who is the first person expressing his intention to participate in the game.
Route train trailer , comprising one or more driven roller conveyors aligned transversely to the longitudinal axis of the vehicle, by means of which a load carrier can be delivered either via one of the two vehicle sides of the route train trailer to a transfer station or can be accommodated by this, and a control and regulation device, characterized in that the route train trailer comprises - one or more data light barriers for wireless data exchange with the transfer station , and - one or more position distance sensors for detecting the position of the load carrier on the roller conveyor or roller conveyors , - wherein the control and regulation device is set up to control the roller rotation direction and/or the roller rotation speed of each of the roller conveyors individually as a function of the position of the load carrier on the roller conveyor or roller conveyors . - one or more data light barriers for wireless data exchange with the transfer station , and - one or more position distance sensors for detecting the position of the load carrier on the roller conveyor or roller conveyors , - wherein the control and regulation device is set up to control the roller rotation direction and/or the roller rotation speed of each of the roller conveyors individually as a function of the position of the load carrier on the roller conveyor or roller conveyors .
A purified T cell receptor (TCR) having affinity for a surface antigen on a target cell, wherein the TCR is a tyrosine-protein kinase HER2/Neu (ERBB2)-specific TCR comprising at least one selected from the group consisting of a TCR alpha chain comprising SEQ ID NOs: 2 or 6 and a TCR beta chain comprising SEQ ID NOs: 4 or 7.
A high-strength steel plate having a chemical composition containing, by mass%, C: 0.040% to 0.090%, Si: 0.05% to 0.30%, Mn: 1.50% to 2.50%, P: 0.020% or less, S: 0.002% or less, Mo: 0.20% to 0.60%, Nb: 0.020% to 0.070%, Ti: 0.020% or less, V: 0.080% or less, Al: 0.045% or less, N: 0.0100% or less, the chemical composition optionally further containing, by mass%, one, two, or more of Cu: 0.50% or less, Ni: 0.50% or less, Cr: 0.50% or less, and Ca: 0.0005% to 0.0040%, and the balance being Fe and inevitable impurities, wherein Ti/N is 2.0 to 4.0, and X calculated by using equation is 0.70% or more, and in which parameter P eff calculated by using equation below is 0.070% or more, satisfying the relationship (TSo - TS)/TSo ≤ 0.050, where TS is defined as tensile strength determined at a temperature of 350°C after aging has been performed under the condition of a Larson-Miller Parameter (LMP) of 15700, and where TSo is defined as tensile strength determined at a temperature of 350°C before the aging is performed, and having toughness represented by a vE- 20 of 100 J or more in a weld heat-affected zone, which is formed when welding is performed: P eff % = 0.13 Nb + 0.24 V − 0.125 Ti / C + 0.86 N X = 0.35 Cr + 0.9 Mo + 12 Nb + 8 V where the symbols of elements in equation and respectively denote the contents (mass%) of the corresponding chemical elements, and where the symbol of a chemical element which is not included is assigned a value of 0.
A lead-acid cell having a positive plate and a negative plate disposed with a container, a separator disposed within said container and separating said positive and negative plates, and an electrolyte within said container, said positive plate comprising a grid supporting structure having a layer of active material thereon, said grid supporting structure comprising a lead-based alloy consisting of lead, from 1.5% to 3.0% tin, from 0.01% to 0.02% copper, from 0.015% to 0.04% bismuth, and from 0.05% to 0.08% calcium, the percentages being based upon the total weight of said lead-based alloy.
A pharmaceutical formulation comprising an anti-epidermal growth factor receptor (EGFR) antibody, sodium acetate anhydrous, and polysorbate 80, wherein no sodium chloride (NaCl) is included in the pharmaceutical formulation, wherein the anti-EGFR antibody is GC1118A, wherein the anti-EGFR antibody is comprised in a concentration of 2 to 10 mg/ml, wherein the sodium acetate anhydrous is comprised in a concentration of 10 to 100 mM, and wherein the polysorbate 80 is comprised in a concentration of 0.05 to 2.0 mg/ml.
Electric or hybrid motor-vehicle (V) with a modular battery system comprising at least one fixed battery module (B1), permanently installed on board of the vehicle (V), at least one removable battery module (B2), and a battery management system (BMS) configured to manage the operation of said battery modules (B1, B2), wherein said at least one removable battery module (B2) comprises an outer casing , a first thermally conductive plate received inside said casing , at least one rechargeable battery pack , which is received inside said casing and is placed in contact with said first plate , an internal circuit which extends inside said first plate and is filled with a heat transfer fluid, and a second thermally conductive plate which is fluidly connected to said internal circuit so as to be flowed through by the heat transfer fluid flowing in said internal circuit and is arranged with an outer face thereof outside of said casing and wherein the motor-vehicle further comprises an auxiliary cooling circuit having at least one direct expansion plate which is fixed to the motor-vehicle (V) and is adapted to be placed in contact with said second plate of said at least one removable battery module (B2), when said at least one removable battery module (B2) is installed on the motor-vehicle (V). wherein said at least one removable battery module (B2) comprises an outer casing , a first thermally conductive plate received inside said casing , at least one rechargeable battery pack , which is received inside said casing and is placed in contact with said first plate , an internal circuit which extends inside said first plate and is filled with a heat transfer fluid, and a second thermally conductive plate which is fluidly connected to said internal circuit so as to be flowed through by the heat transfer fluid flowing in said internal circuit and is arranged with an outer face thereof outside of said casing and wherein the motor-vehicle further comprises an auxiliary cooling circuit having at least one direct expansion plate which is fixed to the motor-vehicle (V) and is adapted to be placed in contact with said second plate of said at least one removable battery module (B2), when said at least one removable battery module (B2) is installed on the motor-vehicle (V).
A connector for child safety seat fastening systems, comprising: - a support frame , provided with a seat adapted to accommodate an anchoring element secured to the seat of an automobile; - a pivotable hook , rotatably mounted on the support frame , said pivotable hook being movable between an inactive position, in which the connector is not fastened to said anchoring element, and an active position, in which a first indentation of the pivotable hook engages said anchoring element, securing the connector to the car seat; and - a locking element , slidable relative to the support frame between a distal position relative to the pivotable hook , wherein said pivotable hook is free to rotate around its axis, and an engagement position, in which one portion of the locking element engages a second indentation in the pivotable hook to block its rotation; characterized in that the locking element comprises a plastic bracket supporting a metal insert , said metal insert being adapted to engage said second indentation in the pivotable hook , so as to block its rotation; and in that a sensor is associated with the plastic bracket , said sensor being adapted to emit a signal indicating the relative position between the plastic bracket and the pivotable hook . - a support frame , provided with a seat adapted to accommodate an anchoring element secured to the seat of an automobile; - a pivotable hook , rotatably mounted on the support frame , said pivotable hook being movable between an inactive position, in which the connector is not fastened to said anchoring element, and an active position, in which a first indentation of the pivotable hook engages said anchoring element, securing the connector to the car seat; and - a locking element , slidable relative to the support frame between a distal position relative to the pivotable hook , wherein said pivotable hook is free to rotate around its axis, and an engagement position, in which one portion of the locking element engages a second indentation in the pivotable hook to block its rotation;
A compound of formula , , or or a pharmaceutically acceptable salt or solvate thereof, wherein: R 1 is C 1 -C 4 alkyl optionally substituted with up to five F atoms, C 3 -C 6 cycloalkyl optionally substituted with one methyl group, or C 4 -C 7 cycloalkylmethyl; R 2 is H, F, Cl or OMe; R 3 is H, OH, OMe, OPO(OH)OH or OCH 2 OPO(OH)OH; R 4 is H, OH, OMe, OPO(OH)OH or OCH 2 OPO(OH)OH; provided that R 3 and R 4 cannot both be H; or R 3 and R 4 combine, together with the phenyl ring to which they are attached, to form an indazole group as shown below R 5 is H, F, Cl or OMe; R 6 is H, F, Cl or OMe; X is N or C-R 7 , wherein R 7 is H or F; R 5 is SF 5 , Br, C 1 -C 3 alkyl optionally substituted with up to seven F atoms, C 3 -C 4 cycloalkyl, OCH 2 C=CH or OC 1 -C 3 alkyl optionally substituted with up to seven F atoms; R 9 is H; and R 10 is H, F or Me. R 1 is C 1 -C 4 alkyl optionally substituted with up to five F atoms, C 3 -C 6 cycloalkyl optionally substituted with one methyl group, or C 4 -C 7 cycloalkylmethyl; R 2 is H, F, Cl or OMe; R 3 is H, OH, OMe, OPO(OH)OH or OCH 2 OPO(OH)OH; R 4 is H, OH, OMe, OPO(OH)OH or OCH 2 OPO(OH)OH; provided that R 3 and R 4 cannot both be H; or R 3 and R 4 combine, together with the phenyl ring to which they are attached, to form an indazole group as shown below R 5 is H, F, Cl or OMe; R 6 is H, F, Cl or OMe; X is N or C-R 7 , wherein R 7 is H or F; R 5 is SF 5 , Br, C 1 -C 3 alkyl optionally substituted with up to seven F atoms, C 3 -C 4 cycloalkyl, OCH 2 C=CH or OC 1 -C 3 alkyl optionally substituted with up to seven F atoms; R 9 is H; and R 10 is H, F or Me.