An iontophoresis administration device , comprising: a power supply (110, 310, 410, 510; 610, 710) for generating electricity required to penetrate a medicament to be penetrated into an administered area of an organism; an integrated dielectric layer for covering the administered area , wherein the integrated dielectric layer comprises: a gel , and the polar, free-state medicament to be penetrated, wherein the gel comprises a matrix, an active medicament and an additive, the active medicament is the polar, free-state medicament to be penetrated; and a plurality of electrodes for electrically connecting with the power supply and the integrated dielectric layer respectively, such that the electricity generated by the power supply flows through the administered area and at least part of the integrated dielectric layer respectively, wherein the at least part of the integrated dielectric layer has a predetermined resistance value (R1) the predetermined resistance value (R1) of the integrated dielectric layer is 10%~90% of skin resistance (R2) of the administered area ; wherein the plurality of electrodes are flexible conductive electrode films separated from each other; the iontophoresis administration device further comprises: a back substrate layer for covering the plurality of electrodes, and the back substrate layer is an insulation material; and a plurality of connectors for electrically connecting the power supply and the plurality of electrodes respectively, each of the plurality of connectors is at least partially disposed in the back substrate layer. a power supply (110, 310, 410, 510; 610, 710) for generating electricity required to penetrate a medicament to be penetrated into an administered area of an organism; an integrated dielectric layer for covering the administered area , wherein the integrated dielectric layer comprises: a gel , and the polar, free-state medicament to be penetrated, wherein the gel comprises a matrix, an active medicament and an additive, the active medicament is the polar, free-state medicament to be penetrated; and a plurality of electrodes for electrically connecting with the power supply and the integrated dielectric layer respectively, such that the electricity generated by the power supply flows through the administered area and at least part of the integrated dielectric layer respectively, wherein the at least part of the integrated dielectric layer has a predetermined resistance value (R1) the predetermined resistance value (R1) of the integrated dielectric layer is 10%~90% of skin resistance (R2) of the administered area ; wherein the plurality of electrodes are flexible conductive electrode films separated from each other; the iontophoresis administration device further comprises: a back substrate layer for covering the plurality of electrodes, and the back substrate layer is an insulation material; and a plurality of connectors for electrically connecting the power supply and the plurality of electrodes respectively, each of the plurality of connectors is at least partially disposed in the back substrate layer. a back substrate layer for covering the plurality of electrodes, and the back substrate layer is an insulation material; and a plurality of connectors for electrically connecting the power supply and the plurality of electrodes respectively, each of the plurality of connectors is at least partially disposed in the back substrate layer. <EOS>