A thermoplastic bottle comprising a bottom wall adapted to define a support plane (SP), a neck provided with an opening of the bottle, a shoulder connected to the neck , and a side wall extending longitudinally around a central axis (Z) of the bottle between the bottom wall and the shoulder ; wherein the side wall has a symmetry plane (P1) including the central axis (Z), a first line (PL1) of the side wall and a second line (PL2) of the side wall being defined in the symmetry plane (PL1), entirely below the shoulder; wherein the second line (PL2) is provided with a second point at a radial distance ds2 from the central axis (Z), which is the minimal distance between the side wall and the central axis (Z); wherein the first line (PL1) is provided with a first point at a radial distance ds1 from the central axis (Z) which is the minimal distance between the first line (PL1) and the central axis (Z); wherein the side wall comprises at the second line (PL2) at least one thick portion that extends at and above the second point , said thick portion having a thickness that is greater than an opposite thickness (E1) provided in the first line (PL1) at same height as the height of the second point ; characterized in that the following relations are satisfied: ds2 < ds1 hs1 < hs2 where hs1 is height of the first point and hs2 is height of the second point , each measured parallel to the central axis (Z) from the support plane (SP), wherein the side wall comprises: - a lower portion adjacent to the bottom wall and extending symmetrically around the central axis (Z); - a first annular part connected to the lower portion , the first annular part and the lower portion intersecting and interconnecting at a substantially circular peripheral intersection line that is perpendicular to the central axis (Z); - a second annular part having an upper annular end perpendicular to the central axis (Z);wherein the second point and the first point are located in a determined annular line tilted with respect to the support plane (SP), the determined annular line defining a peripheral intersection between the first annular part and the second annular part , at a distance from the upper annular end of the second annular part , the first annular part and the second annular part longitudinally tapering in opposite directions and defining a gripping portion of the bottle. ds2 < ds1 hs1 < hs2 - a lower portion adjacent to the bottom wall and extending symmetrically around the central axis (Z); - a first annular part connected to the lower portion , the first annular part and the lower portion intersecting and interconnecting at a substantially circular peripheral intersection line that is perpendicular to the central axis (Z); - a second annular part having an upper annular end perpendicular to the central axis (Z);wherein the second point and the first point are located in a determined annular line tilted with respect to the support plane (SP), the determined annular line defining a peripheral intersection between the first annular part and the second annular part , at a distance from the upper annular end of the second annular part , the first annular part and the second annular part longitudinally tapering in opposite directions and defining a gripping portion of the bottle. <EOS>