mhurhangee/patent-ind-claim-en huggingface dataset:
A chemical compound or a salt or solvate thereof having the structure (II) wherein X is -C(=O)-, -C(=S)-, or -S(=O) 2 -, R 1 is an organic side chain comprising at least 2 C-atoms if X is C(=O), and at least 1 C-atom if X is C(=S) or S(=O) 2 , R 1 is an organic side chain comprising at least 2 C-atoms, R 3 is H or an organic side chain, wherein at least one of R 1 , R 1 and R 3 is a hydrophilic side chain having an octanol/water coefficient (logK OW ) of ≤ 2, wherein R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and R 10 are, independently of each other, selected from the group consisting of H; substituted or unsubstituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkinyl, aryl, heterocycloalkyl, heteroaryl, halogen; -NO 2 , -SO 3 - , -CN, -CH=CH-COOH, and -Y 3 -R 13 with Y 3 being -O-, -C(=O)- or -N(R 14 )-, with R 13 and R 14 being, independently of each other, selected from the group consisting of unsubstituted or substituted, alkyl and aryl, and wherein said organic side chain is an, optionally substituted, alkyl, alkenyl, alkinyl, aryl, aralkyl, cycloalkyl, heterocycloalkyl, or heteroaryl side chain. X is -C(=O)-, -C(=S)-, or -S(=O) 2 -, R 1 is an organic side chain comprising at least 2 C-atoms if X is C(=O), and at least 1 C-atom if X is C(=S) or S(=O) 2 , R 1 is an organic side chain comprising at least 2 C-atoms, R 3 is H or an organic side chain, wherein at least one of R 1 , R 1 and R 3 is a hydrophilic side chain having an octanol/water coefficient (logK OW ) of ≤ 2, wherein R 4 , R 5 , R 6 , R 7 , R 8 , R 9 and R 10 are, independently of each other, selected from the group consisting of H; substituted or unsubstituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkinyl, aryl, heterocycloalkyl, heteroaryl, halogen; -NO 2 , -SO 3 - , -CN, -CH=CH-COOH, and -Y 3 -R 13 with Y 3 being -O-, -C(=O)- or -N(R 14 )-, with R 13 and R 14 being, independently of each other, selected from the group consisting of unsubstituted or substituted, alkyl and aryl, and wherein said organic side chain is an, optionally substituted, alkyl, alkenyl, alkinyl, aryl, aralkyl, cycloalkyl, heterocycloalkyl, or heteroaryl side chain.
A system for lowering a core body temperature of a patient to be used in combination with an external ventilator configured to deliver a breathing gas to a bronchus of a lung of the patient, said system comprising: a tubular device configured for advancement through the patient's trachea to the bronchus, said tubular device having a breathing lumen and a frozen particle, FSP, lumen isolated from the breathing lumen; an external FSP source configured to disperse FSP in a dispersion gas and deliver the dispersed FSP to the FSP lumen of the tubular device; a vent to release an excess portion of the dispersion gas prior to delivery of the dispersed FSP to the FSP lumen of the tubular device; and a controller configured to (a) receive a temperature of an exhaled gas or a body temperature of the patient from a sensor and (b) adjust the amount or rate of delivery of FSP from the external FSP source through the at least one FSP lumen, whereby a target core temperature of the patient can be achieved and maintained by adjusting the amount or rate of delivery of the FSP. a tubular device configured for advancement through the patient's trachea to the bronchus, said tubular device having a breathing lumen and a frozen particle, FSP, lumen isolated from the breathing lumen; an external FSP source configured to disperse FSP in a dispersion gas and deliver the dispersed FSP to the FSP lumen of the tubular device; a vent to release an excess portion of the dispersion gas prior to delivery of the dispersed FSP to the FSP lumen of the tubular device; and a controller configured to (a) receive a temperature of an exhaled gas or a body temperature of the patient from a sensor and (b) adjust the amount or rate of delivery of FSP from the external FSP source through the at least one FSP lumen, whereby a target core temperature of the patient can be achieved and maintained by adjusting the amount or rate of delivery of the FSP.
A blade for an impeller designed according to the method of claim 13, the blade comprising: a blade with a front portion with a leading edge and a trailing portion with a trailing edge joined by spaced apart pressure and suction sides to form an exterior blade surface; wherein the blade pressure side is formed from an outer envelope of a first blade profile aligned in a first position, the blade profile being the design of a blade profile to align flow and ensure that flow remains attached to the blade surface during a set flow condition; and wherein at least a part of the front portion of the blade suction side is formed by rotating the first blade profile around the leading edge to match an angle of the incoming flow at a lower flowrate condition of the impeller. a blade with a front portion with a leading edge and a trailing portion with a trailing edge joined by spaced apart pressure and suction sides to form an exterior blade surface; wherein the blade pressure side is formed from an outer envelope of a first blade profile aligned in a first position, the blade profile being the design of a blade profile to align flow and ensure that flow remains attached to the blade surface during a set flow condition; and wherein at least a part of the front portion of the blade suction side is formed by rotating the first blade profile around the leading edge to match an angle of the incoming flow at a lower flowrate condition of the impeller.
A composition consisting of particles, the particles each comprising a high intensity sweetener, a non-sucrose bulk sweetener and a low digestible carbohydrate polymer, the particles being agglomerates of said components in one and the same particle, where the non-sucrose bulk sweetener is present in an amount of from 85% to 90 % by weight, where the low digestible carbohydrate polymer is present in an amount of from 9 % to 13 % by weight and the high intensity sweetener is present in an amount of from 0.01 % to 1% by weight, where the non-sucrose bulk sweetener is a polyol and where the low digestible carbohydrate polymer is selected from the group consisting of polydextrose, inulin, oligofructose and dextrin.
Use of the application of mechanical stress on megakaryocytes to promote the release of one or more platelet production promoting factors selected from MIF, NRDc, IGFBP2, TSP-1, PAI-1, and CCL5.
A process for welding copper components, selected from copper sheets and copper tubular profiles, comprising the steps of: providing a first component and a second component with respective edges facing each other, the first component being a component made of copper or copper alloy and the second component being a component made of copper or copper alloy or stainless steel; welding said edges by addition of a filler material and under protection of a shielding gas by Gas Metal Arc Welding (GMAW), or by Gas Tungsten Arc Welding (GTAW); the process being characterized in that the components are not pre-heated before the welding step; and in that the filler material is a copper-aluminum alloy containing aluminum in an amount ranging between 7 and 10% in weight, and the shielding gas contains helium in an amount greater than or equal to 90% in volume.
Use of a polyacrylamide resin as a papermaking additive, the polyacrylamide resin having at least one kind of a first unit represented by the following formulas to and a second unit represented by the following formula . (In the above-described formulas to , R1 represents a hydrogen atom, a methyl group, an ethyl group, or a benzyl group; R2 and R3 are independent and represent a hydrogen atom, a methyl group, an ethyl group, or a benzyl group; and X represents an anion.) (In the above-described formula , R4 represents a hydrogen atom or a methyl group and R5 represents a hydrogen atom, an alkali metal ion, or an ammonium ion.)
A vehicle suspension apparatus comprising: a shock absorber that has a cylinder outer tube ; a dust cover whose upper area is fixed on an upper support side; and a coil spring that surrounds the dust cover, wherein the cylinder outer tube has a plurality of first engagement units provided around the cylinder outer tube , and wherein the dust cover has a positioning member that abuts against the first engagement units and determines a relative position of the cylinder outer tube and a lower area of the dust cover in a shaft direction and a plurality of second engagement units that are provided around the lower area of the dust cover , wherein a circumferential width of the first engagement units is formed to be narrower than a circumferential interval of adjacent second engagement units , and a circumferential width of the second engagement units is formed to be narrower than a circumferential interval of adjacent first engagement units , and wherein, by the engagement of the first engagement units with the second engagement units , the lower area of the dust cover becomes locked to the cylinder outer tube in the shaft direction. wherein the cylinder outer tube has a plurality of first engagement units provided around the cylinder outer tube , and wherein the dust cover has a positioning member that abuts against the first engagement units and determines a relative position of the cylinder outer tube and a lower area of the dust cover in a shaft direction and a plurality of second engagement units that are provided around the lower area of the dust cover , wherein a circumferential width of the first engagement units is formed to be narrower than a circumferential interval of adjacent second engagement units , and a circumferential width of the second engagement units is formed to be narrower than a circumferential interval of adjacent first engagement units , and wherein, by the engagement of the first engagement units with the second engagement units , the lower area of the dust cover becomes locked to the cylinder outer tube in the shaft direction.
A thermoacoustic imaging system for use in combination with an existing ultrasound imaging system for imaging features of tissue, the existing ultrasound imaging system including a transmit- receive transducer array comprising a plurality of transmit-receive array elements housed within a first ultrasound probe , wherein the transmit-receive transducer array receives and detects echoes from an ultrasound beam delivered into the tissue by the transmit-receive transducer array , and converts the echoes to ultrasound output signals, the thermoacoustic imaging system comprising: a source of electromagnetic energy; a receive-only transducer array comprising a plurality of receive-only array elements housed within a second ultrasound probe which is in the form of a sleeve that surrounds and is joined mechanically to the first ultrasound probe such that the plurality of receive-only array elements are configured to surround and are in physical alignment and in proximity to the plurality of transmit-receive array elements , wherein the receive-only transducer array receives and detects thermoacoustically-generated acoustic signals in response to electromagnetic energy delivered into the tissue by the source of electromagnetic energy, and converts the thermoacoustically-generated acoustic signals to thermoacoustic output signals; and an imaging assembly configured to process the ultrasound output signals and the thermoacoustic output signals to generate composite images of the features of tissue. a source of electromagnetic energy; a receive-only transducer array comprising a plurality of receive-only array elements housed within a second ultrasound probe which is in the form of a sleeve that surrounds and is joined mechanically to the first ultrasound probe such that the plurality of receive-only array elements are configured to surround and are in physical alignment and in proximity to the plurality of transmit-receive array elements , wherein the receive-only transducer array receives and detects thermoacoustically-generated acoustic signals in response to electromagnetic energy delivered into the tissue by the source of electromagnetic energy, and converts the thermoacoustically-generated acoustic signals to thermoacoustic output signals; and an imaging assembly configured to process the ultrasound output signals and the thermoacoustic output signals to generate composite images of the features of tissue.
A method of producing amplicons derived from a single template barcoded polynucleotide molecule that comprises an exclusion sequence and a barcode in a plurality of vessels comprising a plurality of template barcoded polynucleotide molecules the method comprising: (a) performing a first reaction, whereby a first extension primer comprising an activating sequence anneals to the exclusion sequence in the single template barcoded polynucleotide molecule and is extended, forming an activated barcoded polynucleotide, said activating sequence in the first extension primer comprising at least 2, 3, 4, 5, 6, 7, 8, 9, or 10 mismatches to the exclusion sequence in the template barcoded polynucleotide; (b) performing a second reaction whereby a second extension primer anneals to the activated barcoded polynucleotide, forming a polynucleotide complementary to the activated barcoded polynucleotide and lacking the exclusion sequence ("nonexclusionary template barcoded polynucleotide") and (c) amplifying the activated barcoded polynucleotide and the nonexclusionary template barcoded polynucleotide using a first amplification primer comprising the activating sequence of the first extension primer and a second amplification primer complementary to a sequence of the activated barcoded polynucleotide, forming amplicons comprising a barcode amplified from the single template barcoded polynucleotide molecule; wherein the plurality of vessels comprises at least 50 vessels. (a) performing a first reaction, whereby a first extension primer comprising an activating sequence anneals to the exclusion sequence in the single template barcoded polynucleotide molecule and is extended, forming an activated barcoded polynucleotide, said activating sequence in the first extension primer comprising at least 2, 3, 4, 5, 6, 7, 8, 9, or 10 mismatches to the exclusion sequence in the template barcoded polynucleotide; (b) performing a second reaction whereby a second extension primer anneals to the activated barcoded polynucleotide, forming a polynucleotide complementary to the activated barcoded polynucleotide and lacking the exclusion sequence ("nonexclusionary template barcoded polynucleotide") and (c) amplifying the activated barcoded polynucleotide and the nonexclusionary template barcoded polynucleotide using a first amplification primer comprising the activating sequence of the first extension primer and a second amplification primer complementary to a sequence of the activated barcoded polynucleotide, forming amplicons comprising a barcode amplified from the single template barcoded polynucleotide molecule;
A modular system of intravenous catheters comprising: a cannula assembly comprising: a cannula and a cannula hub ; a needle ; a sleeve defining an internal cavity with an opening at a front end of the sleeve; a needle support attached to the needle at a rear portion of the needle , the needle support being slidably mounted within the internal cavity of the sleeve for movement of the needle from an extended position to a retracted position, the needle support comprising a first engaging element and a second engaging element ; a retractor that applies a force to the needle support biasing the needle support toward the retracted position; and a group of activation hubs comprising a first activation hub and a second activation hub ; wherein the first activation hub is configured to be connected to the front end of the sleeve and comprises a manually actuated release mechanism that engages the first engaging element of the needle support to secure the needle support against the biasing force of the retractor ; and wherein the second activation hub is configured to be connected to the front end of the sleeve and comprises an automatically actuated release mechanism that engages the second engaging element of the needle support to secure the needle support against the biasing force of the retractor . a cannula and a cannula hub ; a needle ; a sleeve defining an internal cavity with an opening at a front end of the sleeve; a needle support attached to the needle at a rear portion of the needle , the needle support being slidably mounted within the internal cavity of the sleeve for movement of the needle from an extended position to a retracted position, the needle support comprising a first engaging element and a second engaging element ; a retractor that applies a force to the needle support biasing the needle support toward the retracted position; and a group of activation hubs comprising a first activation hub and a second activation hub ; wherein the first activation hub is configured to be connected to the front end of the sleeve and comprises a manually actuated release mechanism that engages the first engaging element of the needle support to secure the needle support against the biasing force of the retractor ; and wherein the second activation hub is configured to be connected to the front end of the sleeve and comprises an automatically actuated release mechanism that engages the second engaging element of the needle support to secure the needle support against the biasing force of the retractor .
Fastening arrangement for fastening a component to a groove of a window, a door, or the like, with a component and a clamping element into which a screw is screwed, which protrudes through the component , wherein the screw has a positive and/or non-positive locking end for generating a positive and/or non-positive locking with the groove, characterized in that a clamping piece is provided, a portion of which is arranged between the clamping element and the component , wherein, by means of a rotary motion of the screw , the clamping element can initially be displaced into a clamping position and in its clamping position strikes against a groove wall, for which reason it cannot be turned further, wherein further turning of the screw causes displacement of the clamping element in the direction of the component and the clamping piece is carried along in the direction of the component by the clamping element when the clamping element is displaced, thereby clamping a groove undercut.
A voltage controlled oscillator, VCO, comprising: a resonant tank circuit (L1, L2, C), wherein the resonant tank circuit comprises an inductor-capacitor, LC, tank circuit; an active negative transconductance circuit (M1, M2, Z) connected with the resonant tank circuit, comprising: cross-coupled transistors having drains connected with the resonant tank circuit, wherein the cross-coupled transistors comprise n-channel metal oxide semiconductor, NMOS, field effect transistors (M1, M2), and wherein a body of each of the cross-coupled transistors is connected with a reference voltage; and an impedance (Z) connected between sources of the cross-coupled NMOS transistors and the reference voltage; and a bias current circuit for sourcing or sinking a bias current through the resonant tank circuit and the active negative transconductance circuit to generate an oscillating signal, characterized in that the bias current circuit comprises a current mirror; and the VCO further comprises a switch configured to programmably shunt the impedance. a resonant tank circuit (L1, L2, C), wherein the resonant tank circuit comprises an inductor-capacitor, LC, tank circuit; an active negative transconductance circuit (M1, M2, Z) connected with the resonant tank circuit, comprising: cross-coupled transistors having drains connected with the resonant tank circuit, wherein the cross-coupled transistors comprise n-channel metal oxide semiconductor, NMOS, field effect transistors (M1, M2), and wherein a body of each of the cross-coupled transistors is connected with a reference voltage; and an impedance (Z) connected between sources of the cross-coupled NMOS transistors and the reference voltage; and cross-coupled transistors having drains connected with the resonant tank circuit, wherein the cross-coupled transistors comprise n-channel metal oxide semiconductor, NMOS, field effect transistors (M1, M2), and wherein a body of each of the cross-coupled transistors is connected with a reference voltage; and an impedance (Z) connected between sources of the cross-coupled NMOS transistors and the reference voltage; and a bias current circuit for sourcing or sinking a bias current through the resonant tank circuit and the active negative transconductance circuit to generate an oscillating signal, characterized in that the bias current circuit comprises a current mirror; and the VCO further comprises a switch configured to programmably shunt the impedance.
An aqueous composition comprising: (a) 10% to 80% at least one poorly water soluble biocide, by solids weight, based on the total weight of said aqueous composition, (b) 0.1% to 30% at least one pH-sensitive dispersed polymer, by solids weight, based on the total weight of said aqueous composition, and (c) 0% to 10% pH-insensitive polymer, by solids weight, based on the total weight of said aqueous composition, wherein said pH-sensitive dispersed polymer is a polymer with weight-average molecular weight of 500,000 or greater, or is a crosslinked polymer, or is a mixture thereof. (a) 10% to 80% at least one poorly water soluble biocide, by solids weight, based on the total weight of said aqueous composition, (b) 0.1% to 30% at least one pH-sensitive dispersed polymer, by solids weight, based on the total weight of said aqueous composition, and (c) 0% to 10% pH-insensitive polymer, by solids weight, based on the total weight of said aqueous composition,
A stackable basket for dishwashing machines, comprising: - a bottom wall and four sidewalls , each sidewall of said four sidewalls having an upper portion and an opposite lower portion , said upper portion being more internal with respect to said lower portion in the direction of the central part of said basket , - each upper portion comprises at least one recess extending toward said bottom wall , - each lower portion comprises at least one pair of ribs spaced apart and connecting said lower portion to said bottom wall , - wherein two baskets can be stacked in an engagement position in which the lower portion of the upper basket at least partially overlaps the upper portion of the lower basket in said engagement position, and said at least one pair of ribs in the lower portion of the upper basket are at least partially inserted in a corresponding recess in the upper portion of the lower basket ; characterised in that: - each recess comprises a horizontal lower side and two vertical sides opposite to each other and orthogonal to said lower side and spaced apart by a first distance (D') which is comprised between 10% and 30% of the total length (L) of said sidewall . - a bottom wall and four sidewalls , each sidewall of said four sidewalls having an upper portion and an opposite lower portion , said upper portion being more internal with respect to said lower portion in the direction of the central part of said basket , - each upper portion comprises at least one recess extending toward said bottom wall , - each lower portion comprises at least one pair of ribs spaced apart and connecting said lower portion to said bottom wall , - wherein two baskets can be stacked in an engagement position in which the lower portion of the upper basket at least partially overlaps the upper portion of the lower basket in said engagement position, and said at least one pair of ribs in the lower portion of the upper basket are at least partially inserted in a corresponding recess in the upper portion of the lower basket ; characterised in that: - each recess comprises a horizontal lower side and two vertical sides opposite to each other and orthogonal to said lower side and spaced apart by a first distance (D') which is comprised between 10% and 30% of the total length (L) of said sidewall .