mhurhangee/patent-ind-claim-en huggingface dataset:
A method for use in a User Equipment, UE, for performing measurements in a wireless communication network, the method comprising: - acquiring system information, SI, of a cell during autonomous gaps created by the UE; and - performing a non-SI measurement related to a serving cell and/or to one or more neighbour cells during a time period comprising the autonomous gaps, wherein the non-SI measurement is performed in-between the created autonomous gaps, and wherein a non-SI measurement related to a serving cell is at least a Radio Link Monitoring measurement. - acquiring system information, SI, of a cell during autonomous gaps created by the UE; and - performing a non-SI measurement related to a serving cell and/or to one or more neighbour cells during a time period comprising the autonomous gaps, wherein the non-SI measurement is performed in-between the created autonomous gaps, and wherein a non-SI measurement related to a serving cell is at least a Radio Link Monitoring measurement.
A multi-gear brightness adjustment circuit board, comprising a plurality of gear conductive contact pieces disposed sequentially along a circumferential direction of a top surface of a circuit board and with gradually increased gear, characterized in that the circuit board is also disposed with an automatic control gear AUTO conductive contact piece and a light spot dot-circle pattern composite conductive contact piece disposed along the circumferential direction of the circuit board in the circumferential direction.
A compound which is the following compound: wherein m equals 1 and z is an integer selected from the following group: z = 1 to 5.
A mammalian cell having enhanced secretion of a recombinant therapeutic protein comprising (a) reduced expression of the host cell proteins TBC1 domain family member 20 (TBC1D20) and ceramide synthase 2 (CERS2); or (b) reduced expression of the host cell protein activating transcription factor 6 beta (ATF6B), wherein the mammalian cell further comprises one or more expression cassette(s) encoding a recombinant secreted therapeutic protein, wherein: (a) the gene encoding the host cell protein comprises a genetic modification that inhibits expression of said host cell protein, or (b) the mammalian cell comprises a RNA oligonucleotide that inhibits expression of the gene encoding said host cell protein by RNA-interference, and wherein the protein expression of TBC 1D20 and CERS2 or the protein expression of ATF6B in the mammalian cell is reduced compared to the same mammalian cell not containing said genetic modification(s) or RNA oligonucleotide(s). (a) reduced expression of the host cell proteins TBC1 domain family member 20 (TBC1D20) and ceramide synthase 2 (CERS2); or (b) reduced expression of the host cell protein activating transcription factor 6 beta (ATF6B), wherein the mammalian cell further comprises one or more expression cassette(s) encoding a recombinant secreted therapeutic protein, wherein: (a) the gene encoding the host cell protein comprises a genetic modification that inhibits expression of said host cell protein, or (b) the mammalian cell comprises a RNA oligonucleotide that inhibits expression of the gene encoding said host cell protein by RNA-interference, and wherein the protein expression of TBC 1D20 and CERS2 or the protein expression of ATF6B in the mammalian cell is reduced compared to the same mammalian cell not containing said genetic modification(s) or RNA oligonucleotide(s). (a) the gene encoding the host cell protein comprises a genetic modification that inhibits expression of said host cell protein, or (b) the mammalian cell comprises a RNA oligonucleotide that inhibits expression of the gene encoding said host cell protein by RNA-interference, and
An authenticity determining member comprising: a substrate layer that is a reflective circular polarizer; a first print layer that contains a resin pigment including flakes of a resin layer A1 having cholesteric regularity, the first print layer being provided on the substrate layer ; and a second print layer that contains a metal pigment having no circularly polarized light separation function, the second print layer being provided on the substrate layer . a substrate layer that is a reflective circular polarizer; a first print layer that contains a resin pigment including flakes of a resin layer A1 having cholesteric regularity, the first print layer being provided on the substrate layer ; and a second print layer that contains a metal pigment having no circularly polarized light separation function, the second print layer being provided on the substrate layer .
A pharmaceutical composition comprising: 3-(6-(1-(2,2-difluorobenzo[d] dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid characterized as Form I; a pharmaceutically acceptable carrier; and an additional therapeutic agent selected from a mucolytic agent, bronchodialator, an anti-biotic, an anti-infective agent, an anti-inflammatory agent, a cystic fibrosis transmembrane conductance regulator (CFTR) modulator, or a nutritional agent, wherein Form I is characterized as a crystal form having a monoclinic crystal system, a P2 1 /n space group, and the following unit cell dimensions: a = 4.9626 Å α = 90° b = 12.2994 Å β = 93.938 ° c = 33.075 Å γ = 90°, and/or wherein Form I is characterized by one or more peaks at 15.4 degrees ± 0.2 degrees, 16.3 degrees ± 0.2 degrees, and 14.5 degrees ± 0.2 degrees in an X-ray powder diffraction obtained using Cu K alpha radiation at 40 kV, 35 mA. 3-(6-(1-(2,2-difluorobenzo[d] dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid characterized as Form I; a pharmaceutically acceptable carrier; and an additional therapeutic agent selected from a mucolytic agent, bronchodialator, an anti-biotic, an anti-infective agent, an anti-inflammatory agent, a cystic fibrosis transmembrane conductance regulator (CFTR) modulator, or a nutritional agent, wherein Form I is characterized as a crystal form having a monoclinic crystal system, a P2 1 /n space group, and the following unit cell dimensions: a = 4.9626 Å α = 90° b = 12.2994 Å β = 93.938 ° c = 33.075 Å γ = 90°, and/or wherein Form I is characterized by one or more peaks at 15.4 degrees ± 0.2 degrees, 16.3 degrees ± 0.2 degrees, and 14.5 degrees ± 0.2 degrees in an X-ray powder diffraction obtained using Cu K alpha radiation at 40 kV, 35 mA.
An optical slicer for generating an output spot comprising: a beam compressor configured to receive a substantially collimated input beam and to produce a substantially collimated compressed beam; a beam reformatter configured to receive the compressed beam and to divide the beam into a plurality of sliced beam portions and to vertically stack the portions substantially parallel to each other to create a substantially collimated reformatted beam that is larger in the vertical direction and smaller in the horizontal direction compared to the compressed beam; and a beam expander configured to expand the reformatted beam to produce a substantially collimated output beam which, if passed through a focusing lens, produces in the focal plane of the focusing lens the output spot that is expanded in a first dimension and compressed in a second dimension relative to a spot produced in the focal plane of the focusing lens by passing the input beam through the focusing lens in the same manner. a beam compressor configured to receive a substantially collimated input beam and to produce a substantially collimated compressed beam; a beam reformatter configured to receive the compressed beam and to divide the beam into a plurality of sliced beam portions and to vertically stack the portions substantially parallel to each other to create a substantially collimated reformatted beam that is larger in the vertical direction and smaller in the horizontal direction compared to the compressed beam; and a beam expander configured to expand the reformatted beam to produce a substantially collimated output beam which, if passed through a focusing lens, produces in the focal plane of the focusing lens the output spot that is expanded in a first dimension and compressed in a second dimension relative to a spot produced in the focal plane of the focusing lens by passing the input beam through the focusing lens in the same manner.
A negative-pressure continuous grain dryer with a built-in heating device, comprising a dryer bin , a heating device , and a centrifugal fan , wherein a plurality of levels of the heating devices are disposed from top to bottom in the dryer bin, a grain mixing device is provided below the heating device at each level, an auxiliary heating device and a natural air inlet are provided outside the bin and in correspondence with the heating device at each level, the heating devices being uniformly distributed in the dryer bin, the auxiliary heating devices and the natural air inlets are in communication with the grains and the heating devices in the dryer bin through a perforated baffle plate , the centrifugal fan is in communication with each of moisture exhaust vents at each level through an air duct . a dryer bin , a heating device , and a centrifugal fan , wherein a plurality of levels of the heating devices are disposed from top to bottom in the dryer bin, a grain mixing device is provided below the heating device at each level, an auxiliary heating device and a natural air inlet are provided outside the bin and in correspondence with the heating device at each level, the heating devices being uniformly distributed in the dryer bin, the auxiliary heating devices and the natural air inlets are in communication with the grains and the heating devices in the dryer bin through a perforated baffle plate , the centrifugal fan is in communication with each of moisture exhaust vents at each level through an air duct .
A blood filter comprising a porous element; and a copolymer which exists in at least a part of a surface of the porous element, and which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b): wherein U a1 , U a2 , U b1 , U b2 and U b3 each independently represent a hydrogen atom or a linear or branched alkyl group having 1 to 5 carbon atoms, and An - represents an anion selected from the group consisting of a halide ion, an inorganic acid ion, a hydroxide ion and an isothiocyanate ion. a porous element; and a copolymer which exists in at least a part of a surface of the porous element, and which contains a recurring unit containing an organic group of the following formula (a) and a recurring unit containing an organic group of the following formula (b): wherein U a1 , U a2 , U b1 , U b2 and U b3 each independently represent a hydrogen atom or a linear or branched alkyl group having 1 to 5 carbon atoms, and An - represents an anion selected from the group consisting of a halide ion, an inorganic acid ion, a hydroxide ion and an isothiocyanate ion.
A sports training aid comprising two arm members joined together so that an angle between the two arm members is set or is able to be set to a predetermined angle, a first of the two arm members extending as an elongate handle member and the second of the two arm members forming part of a spacing member and being joined at a joint to a spacing arm extending from the joint to a positioning piece , the joint being angled such that the spacing arm is angled towards the first arm member and extends at a bend angle relative to the second arm member , wherein the joint permits the spacing arm to rotate relative to the first arm member about an axis substantially aligned with the second arm member .
A catalytic process for preparing an α,β-ethylenically unsaturated carboxylic acid salt, wherein a) an alkene and carbon dioxide are contacted with a carboxylation catalyst and an alkoxide in an aprotic organic solvent, the alkoxide having a secondary or tertiary carbon atom directly bound to a [O - ] group, to obtain a crude reaction product comprising the α,β-ethylenically unsaturated carboxylic acid salt and an alcohol byproduct which is the conjugate acid of the alkoxide, b) at least part of the crude reaction product is contacted with a polar solvent which is an aqueous phase such that a first liquid phase in which the α,β-ethylenically unsaturated carboxylic acid salt is enriched, and a second liquid phase in which the carboxylation catalyst is enriched, are obtained, and c) an alcohol byproduct is distilled off from the first liquid phase. a) an alkene and carbon dioxide are contacted with a carboxylation catalyst and an alkoxide in an aprotic organic solvent, the alkoxide having a secondary or tertiary carbon atom directly bound to a [O - ] group, to obtain a crude reaction product comprising the α,β-ethylenically unsaturated carboxylic acid salt and an alcohol byproduct which is the conjugate acid of the alkoxide, b) at least part of the crude reaction product is contacted with a polar solvent which is an aqueous phase such that a first liquid phase in which the α,β-ethylenically unsaturated carboxylic acid salt is enriched, and a second liquid phase in which the carboxylation catalyst is enriched, are obtained, and c) an alcohol byproduct is distilled off from the first liquid phase.
An anhydrous, non-solvated crystalline form of (10 R )-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2 H -8,4-(metheno)pyrazolo[4,3- h ] benzoxadiazacyclotetradecine-3-carbonitrile (lorlatinib) free base, having a 19 F solid state NMR spectrum comprising resonance (ppm) values of: -108.2 and -115.2 ppm ± 0.2 ppm, relative to an external standard of 50/50 volume/volume of trifluoroacetic acid and water, setting its resonances to -76.54 ppm.
A solid state power controller, comprising a power supply line configured to be connected between a power source and a load ; a semiconductor switching unit provided on the power supply line and configured to switch between at least three states, including a conducting state, a non-conducting state and an intermediate state, according to a command signal, wherein the semiconductor switching unit is configured to, in the intermediate state, limit a current on the power supply line , according to the command signal, to be below a predetermined current threshold; and wherein the semiconductor switching unit is formed by one or more non-programmable electronic components; a state machine configured to exhibit at least three states including an ON state, an OFF state and a pre-charge state; output the command signal according to a current state of the state machine ; the command signal indicates the semiconductor switching unit to be in the intermediate state if the current state of the state machine is the pre-charge state; characterized in that the state machine is a non-programmable logic part formed by a plurality of non-programmable electronic components and is configured to allow for transitions from the OFF state to the pre-charge state, from the pre-charge state to the OFF state, from the pre-charge state to the ON state, and from the ON state to the OFF state. a power supply line configured to be connected between a power source and a load ; a semiconductor switching unit provided on the power supply line and configured to switch between at least three states, including a conducting state, a non-conducting state and an intermediate state, according to a command signal, wherein the semiconductor switching unit is configured to, in the intermediate state, limit a current on the power supply line , according to the command signal, to be below a predetermined current threshold; and wherein the semiconductor switching unit is formed by one or more non-programmable electronic components; a state machine configured to exhibit at least three states including an ON state, an OFF state and a pre-charge state; output the command signal according to a current state of the state machine ; exhibit at least three states including an ON state, an OFF state and a pre-charge state; output the command signal according to a current state of the state machine ; the command signal indicates the semiconductor switching unit to be in the intermediate state if the current state of the state machine is the pre-charge state; characterized in that the state machine is a non-programmable logic part formed by a plurality of non-programmable electronic components and is configured to allow for transitions from the OFF state to the pre-charge state, from the pre-charge state to the OFF state, from the pre-charge state to the ON state, and from the ON state to the OFF state.
A luminescent rare earth compound, selected from the group comprising: Eu 0.6 Y 0.4 (Benzoic acid) 3, Eu 0.6 Y 0.4 (Isophthalic acid) 1.5, Eu 0.2 Y 0.8 (1,3,5-Benzene-tricarboxylic acid) 1, Tb 0.2 Y 0.8 (1,3,5-Benzene-tricarboxylic acid) 1, Eu 0.5 Y 0.5 (1,2,4,5-Benzene-tetracarboxylic acid) 0.75, Eu (Pyridine-4-carboxylic acid) 3, and /or Eu 0.6 Y 0.4 (2,5-Pyridinedicarboxylic acid) 1.5. Eu 0.6 Y 0.4 (Benzoic acid) 3, Eu 0.6 Y 0.4 (Isophthalic acid) 1.5, Eu 0.2 Y 0.8 (1,3,5-Benzene-tricarboxylic acid) 1, Tb 0.2 Y 0.8 (1,3,5-Benzene-tricarboxylic acid) 1, Eu 0.5 Y 0.5 (1,2,4,5-Benzene-tetracarboxylic acid) 0.75, Eu (Pyridine-4-carboxylic acid) 3, and /or Eu 0.6 Y 0.4 (2,5-Pyridinedicarboxylic acid) 1.5.
Means for the destructive disposal of medical active ingredients present in transdermal therapeutic systems TTS, which means can be stored separate from the medical active ingredient intended for destructive disposal and can be contacted with the TTS after said TTS has been used, wherein the means possesses a multilayer construction, and comprises at least one layer with agent incorporated therein, wherein the layer with agent incorporated therein is a polymeric layer with agent incorporated therein or a pressure-sensitive adhesive layer with agent incorporated therein, characterized in that the means comprises at least one woven fabric, a knitted fabric or a nonwoven fabric made from mineral fibers, in particular glass, mineral wool, basalt, from animal fibers such as silk or wool, from plant fibers, in particular such as cotton or from chemical fibers composed of natural or synthetic polymers, in particular polyamide, polyimide, polytetrafluoroethylene, polyethylene, polypropylene, polyvinyl chloride, polyacrylate or polymethacrylate, polystyrene or polyester, wherein the agent is potassium permanganate or potassium nitrite in solid or pastelike form.
A respiratory system comprising: a respirator having a controller , and a pulse oximeter electrically coupled to the respirator , the pulse oximeter configured for measuring a photoplethysmograph signal, wherein the controller is configured to determine a respiratory rate from the photoplethysmograph signal using the steps of: (i) filtering the photoplethysmograph signal to create a filtered photoplethysmograph signal, (ii) detecting peaks and valleys in the filtered photoplethysmograph signal to extract predetermined features from the filtered photoplethysmograph signal, (iii) obtaining variation waveforms from the predetermined features, (iv) removing outliers from each of variation waveforms, (v) interpolating for the outliers removed from each of the variation waveforms to acquire a frequency estimation of each of the variation waveforms, (vi) determining a respiratory rate based on the frequency estimation of each of the variation waveforms, and (vii) determining a weighted average of the respiratory rate of the variation waveforms to determine an estimated respiratory rate. a respirator having a controller , and a pulse oximeter electrically coupled to the respirator , the pulse oximeter configured for measuring a photoplethysmograph signal, wherein the controller is configured to determine a respiratory rate from the photoplethysmograph signal using the steps of: (i) filtering the photoplethysmograph signal to create a filtered photoplethysmograph signal, (ii) detecting peaks and valleys in the filtered photoplethysmograph signal to extract predetermined features from the filtered photoplethysmograph signal, (iii) obtaining variation waveforms from the predetermined features, (iv) removing outliers from each of variation waveforms, (v) interpolating for the outliers removed from each of the variation waveforms to acquire a frequency estimation of each of the variation waveforms, (vi) determining a respiratory rate based on the frequency estimation of each of the variation waveforms, and (vii) determining a weighted average of the respiratory rate of the variation waveforms to determine an estimated respiratory rate. (i) filtering the photoplethysmograph signal to create a filtered photoplethysmograph signal, (ii) detecting peaks and valleys in the filtered photoplethysmograph signal to extract predetermined features from the filtered photoplethysmograph signal, (iii) obtaining variation waveforms from the predetermined features, (iv) removing outliers from each of variation waveforms, (v) interpolating for the outliers removed from each of the variation waveforms to acquire a frequency estimation of each of the variation waveforms, (vi) determining a respiratory rate based on the frequency estimation of each of the variation waveforms, and (vii) determining a weighted average of the respiratory rate of the variation waveforms to determine an estimated respiratory rate.
A device for intracellular transport of an active principle dissolved in a gel, wherein said device comprises two electrodes , wherein a first of said electrodes is configured to contain the active principle to be administered, the device further comprising a wave generator configured to generate a driving signal to be sent to said electrodes , wherein said driving signal includes a plurality of packets (P) grouped into trains of packets (Tr) and into groups of trains (TG), wherein each packet (P) consists of a unidirectional signal resulting from the combination of a modulating signal and a carrier signal , wherein each train of packets (Tr) consists of a series of packets (P), in which each group of trains (TG) comprises a series of trains of packets (Tr), and wherein said wave generator is configured to at least reverse the polarity of said trains of packets (Tr); the device being configured to generate said carrier signals , wherein the carrier signals of each train of packets (Tr) have a frequency f p dependent upon a penetration depth p, the frequency f p being calculated according to the following formula: ƒ p = 2000 − 180 ∗ p cm Hz , characterized in that the device further comprises a handpiece (200, said first electrode is connected to the handpiece and comprises a magnetic transducer, wherein said magnetic transducer is driven by means of said driving signal, said magnetic transducer comprising a solenoid having a ring shape and being built into said handpiece , said device being configured to generate at least a further driving signal generated by said wave generator to drive the solenoid and in that said device is configured to generate at least further modulating signals to build waveforms comprising packets (P) and trains of packets (Tr) and groups of trains of packets (Tg) and groups of groups of trains, said device being configured to generate a first train of packets (Tr1) having a first carrier signal frequency (fp11), a second train of packets (Tr4) having a second carrier signal frequency (fp14), said second carrier signal frequency (fp4) being lower than the first carrier signal frequency (fp1), and to generate intermediate train of packets (Tr2, Tr3) having carrier signal frequencies (fp12,fp13) that are intermediate between said first carrier signal frequency (fp11) and said second carrier signal frequency (fp14), said frequencies being calculated to act exclusively at the desired penetration depth.