A system for measuring a physical property within a single cell in a nanopore array, comprising: a molecular complex comprising a nanopore; an electrode electrically coupled to the molecular complex, the electrode configured to output an electrical signal that is affected by an electrical property of the molecular complex and a molecule passing through the nanopore, wherein the electrical property is a current through the nanopore; and further characterized in that it comprises: an integrating amplifier configured to: receive the electrical signal from the electrode; initiate an integration of the electrical signal based on an initiation flag ; reset the integrating amplifier; selectively amplify and integrate a portion of the electrical signal overtime within abandwidth of interest; compare the selectively amplified and integrated electrical signal to a threshold ; output an indication that the selectively amplified and integrated electrical signal has reached the threshold; terminate the integration based on the indication; and a processor programmed to determine the physical property within the cell of the nanopore array based in part on a duration of time between an assertion of the initiation flag and an assertion of the indication. a molecular complex comprising a nanopore; an electrode electrically coupled to the molecular complex, the electrode configured to output an electrical signal that is affected by an electrical property of the molecular complex and a molecule passing through the nanopore, wherein the electrical property is a current through the nanopore; and further characterized in that it comprises: an integrating amplifier configured to: receive the electrical signal from the electrode; initiate an integration of the electrical signal based on an initiation flag ; reset the integrating amplifier; selectively amplify and integrate a portion of the electrical signal overtime within abandwidth of interest; compare the selectively amplified and integrated electrical signal to a threshold ; output an indication that the selectively amplified and integrated electrical signal has reached the threshold; terminate the integration based on the indication; and a processor programmed to determine the physical property within the cell of the nanopore array based in part on a duration of time between an assertion of the initiation flag and an assertion of the indication. an integrating amplifier configured to: receive the electrical signal from the electrode; initiate an integration of the electrical signal based on an initiation flag ; reset the integrating amplifier; selectively amplify and integrate a portion of the electrical signal overtime within abandwidth of interest; compare the selectively amplified and integrated electrical signal to a threshold ; output an indication that the selectively amplified and integrated electrical signal has reached the threshold; terminate the integration based on the indication; and receive the electrical signal from the electrode; initiate an integration of the electrical signal based on an initiation flag ; reset the integrating amplifier; selectively amplify and integrate a portion of the electrical signal overtime within abandwidth of interest; compare the selectively amplified and integrated electrical signal to a threshold ; output an indication that the selectively amplified and integrated electrical signal has reached the threshold; terminate the integration based on the indication; and a processor programmed to determine the physical property within the cell of the nanopore array based in part on a duration of time between an assertion of the initiation flag and an assertion of the indication. <EOS>