mhurhangee/patent-ind-claim-en huggingface dataset:
A peptide for use in the reduction of side-effects in the form of immunostimulatory reactions/effects which occur with gene therapy, wherein the peptide is coupled to a nucleic acid molecule used in gene therapy, wherein the peptide consists of up to 300 amino acids, wherein the peptide comprises the cleavage sequence for Legumain (cleavage sequence: Ala-Ala-Asn).
Method for manufacturing a burner lance, the method comprises the step of: a) providing at least a nozzle insert produced by a machining method wherein the nozzle insert is configured for realizing a liquid fuel injection with an injecting spray pattern; b) additive manufacturing a first portion of the burner lance starting from the tip up to an intermediate built-height is reached, wherein at the liquid nozzle a through opening is obtained having a size suitable for receiving the nozzle insert; c) fitting the nozzle insert in the through opening realized during the previous step at the liquid nozzle; d) additive manufacturing the remaining portions of the burner lance wherein the base for the first additive layer of this step is the portion of the burner lance realized in step b) provided with the nozzle insert according to the step c) . a) providing at least a nozzle insert produced by a machining method wherein the nozzle insert is configured for realizing a liquid fuel injection with an injecting spray pattern; b) additive manufacturing a first portion of the burner lance starting from the tip up to an intermediate built-height is reached, wherein at the liquid nozzle a through opening is obtained having a size suitable for receiving the nozzle insert; c) fitting the nozzle insert in the through opening realized during the previous step at the liquid nozzle; d) additive manufacturing the remaining portions of the burner lance wherein the base for the first additive layer of this step is the portion of the burner lance realized in step b) provided with the nozzle insert according to the step c) .
A printing apparatus comprising: feeding means for feeding a printing sheet stacked on a stacking means ; conveying means for conveying the printing sheet fed by said feeding means; printing means for printing the printing sheet conveyed by said conveying means; and control means for controlling said feeding means and said conveying means; characterized in that the control means is capable of controlling conveyance of printing sheets so that an overlap state, in which a trailing edge of a preceding printing sheet and a leading edge of a succeeding printing sheet overlap each other, is formed by controlling the feeding means to form the overlap state and the conveying means to convey the printing sheets while keeping the overlap state, wherein when continuously printing on first surfaces of a plurality of printing sheets, said control means controls the conveyance of the printing sheets so that the overlap state is formed, and when performing double-sided printing on first surfaces and second surfaces of a plurality of printing sheets, said control means controls the conveyance of the printing sheets so that the overlap state is not formed by controlling the feeding means and the conveying means so that the feeding means does not form the overlap state. feeding means for feeding a printing sheet stacked on a stacking means ; conveying means for conveying the printing sheet fed by said feeding means; printing means for printing the printing sheet conveyed by said conveying means; and control means for controlling said feeding means and said conveying means; characterized in that the control means is capable of controlling conveyance of printing sheets so that an overlap state, in which a trailing edge of a preceding printing sheet and a leading edge of a succeeding printing sheet overlap each other, is formed by controlling the feeding means to form the overlap state and the conveying means to convey the printing sheets while keeping the overlap state, wherein when continuously printing on first surfaces of a plurality of printing sheets, said control means controls the conveyance of the printing sheets so that the overlap state is formed, and when performing double-sided printing on first surfaces and second surfaces of a plurality of printing sheets, said control means controls the conveyance of the printing sheets so that the overlap state is not formed by controlling the feeding means and the conveying means so that the feeding means does not form the overlap state.
A device for attaching a balancing weight to a mounting surface on an inner side of a rim dish of a wheel rim , comprising a mounting head which is dimensioned in such a way that it fits into the rim dish and which includes a support element , which is radially displaceable relative to the wheel rim and on which a feeler element is axially movably arranged, wherein the feeler element has at its free end a feeler head , which is configured such that it is movable into a cavity of the wheel rim and the feeler head comprises a receptacle for at least one balancing weight , that is aligned towards the rim inner side and has a convex curved surface, and the side of the feeler head facing the rim inner side is bent radially according to the curvature of the rim inner side , wherein adjacent to the receptacle a convex contact surface with a circularly curved edge region is arranged, and wherein the mounting head being configured in such a way that the contact surface can be brought into contact with a boundary surface of the inner side , and may be displaced along said boundary surface until the balancing weight comes radially into contact with the mounting surface .
A vacuum cleaner, comprising: a dirt inlet ; a motor and fan for delivering suction to the dirt inlet ; a cyclone unit for separating particles from a flow generated by the suction of the motor and fan, comprising a vortex finder extending along a cyclone axis of rotation and an annular chamber formed around the outside of the vortex finder , the annular chamber having a ceiling wall; and a delivery duct for delivering air to the cyclone unit such that it can flow to the annular chamber, wherein the delivery duct extends in a forward airflow direction, and the outlet from the vortex finder is at a backward end thereof such that outlet from the vortex finder has a component in the opposite direction to the forward airflow direction, characterized in that : a space is provided between a forward end of the vortex finder and the ceiling wall, and in that the vacuum cleaner further comprises: a filter located forward of the vortex finder; and a passageway from a backward end of the vortex finder to the filter . a dirt inlet ; a motor and fan for delivering suction to the dirt inlet ; a cyclone unit for separating particles from a flow generated by the suction of the motor and fan, comprising a vortex finder extending along a cyclone axis of rotation and an annular chamber formed around the outside of the vortex finder , the annular chamber having a ceiling wall; and a delivery duct for delivering air to the cyclone unit such that it can flow to the annular chamber, wherein the delivery duct extends in a forward airflow direction, and the outlet from the vortex finder is at a backward end thereof such that outlet from the vortex finder has a component in the opposite direction to the forward airflow direction, characterized in that : a space is provided between a forward end of the vortex finder and the ceiling wall, and in that the vacuum cleaner further comprises: a filter located forward of the vortex finder; and a passageway from a backward end of the vortex finder to the filter . a space is provided between a forward end of the vortex finder and the ceiling wall, and in that the vacuum cleaner further comprises: a filter located forward of the vortex finder; and a passageway from a backward end of the vortex finder to the filter . a filter located forward of the vortex finder; and a passageway from a backward end of the vortex finder to the filter .
A fiber width adjustment device comprising: a feeder configured to feed a tape material (T) in a length direction of the tape material (T), the tape material (T) consisting of fibers for a fiber reinforced resin after or before the fibers are impregnated with a resin; and an adjuster having a path for the tape material (T), the path being formed by at least a bottom and a pair of wall surfaces, an interval of the wall surfaces decreasing gradually such that a width of the tape material (T) which passed the path can be changed by adjusting a part of the path , the tape material (T) passing through the part of the path while contacting with the bottom and the wall surfaces, the bottom having a convex surface, wherein the width of the tape material (T) can be adjusted by adjusting a position where the tape material (T) departs from the path , and wherein the adjuster is configured to adjust the position, at which the tape material (T) departs, by moving the path in a direction parallel to a thickness direction of the tape material (T), the path being moveable relatively to the tape material (T). a feeder configured to feed a tape material (T) in a length direction of the tape material (T), the tape material (T) consisting of fibers for a fiber reinforced resin after or before the fibers are impregnated with a resin; and an adjuster having a path for the tape material (T), the path being formed by at least a bottom and a pair of wall surfaces, an interval of the wall surfaces decreasing gradually such that a width of the tape material (T) which passed the path can be changed by adjusting a part of the path , the tape material (T) passing through the part of the path while contacting with the bottom and the wall surfaces, the bottom having a convex surface, wherein the width of the tape material (T) can be adjusted by adjusting a position where the tape material (T) departs from the path , and wherein the adjuster is configured to adjust the position, at which the tape material (T) departs, by moving the path in a direction parallel to a thickness direction of the tape material (T), the path being moveable relatively to the tape material (T).
A medical device for treating hip joint osteoarthritis, said medical device comprising: at least one artificial hip joint surface configured to replace an articulating carrying surface of at least one of an acetabulum and a caput femur, wherein said artificial hip joint surface comprises a first sealing member , wherein the medical device being adapted to seal a hollow space together with at least one of: the acetabulum surface, an artificial acetabulum surface, the caput femur surface and an artificial caput femur surface, and wherein the medical device is adapted to receive injected material into the sealed hollow space for creating an articulating artificial hip joint surface. at least one artificial hip joint surface configured to replace an articulating carrying surface of at least one of an acetabulum and a caput femur, wherein said artificial hip joint surface comprises a first sealing member , wherein the medical device being adapted to seal a hollow space together with at least one of: the acetabulum surface, an artificial acetabulum surface, the caput femur surface and an artificial caput femur surface, and wherein the medical device is adapted to receive injected material into the sealed hollow space for creating an articulating artificial hip joint surface.
A molecule comprising (i) a first domain, wherein said first domain is formed by a fragment of an antibody, wherein said fragment of an antibody specifically binds to a cell surface molecule at the cell surface of a tumor cell, wherein said cell surface molecule at the cell surface of the tumor cell is CD33; (ii) a second domain, wherein said second domain is formed by an IgG Fc domain that specifically binds to a cell surface molecule at the cell surface of an immune cell, wherein said cell surface molecule at the cell surface of the immune cell is CD16, CD32a or CD64; and (iii) a third domain, wherein said third domain is formed by one or more SirpIg domains that specifically bind to a checkpoint molecule at the cell surface of said tumor cell, wherein said checkpoint molecule at the cell surface of said tumor cell is CD47. (i) a first domain, wherein said first domain is formed by a fragment of an antibody, wherein said fragment of an antibody specifically binds to a cell surface molecule at the cell surface of a tumor cell, wherein said cell surface molecule at the cell surface of the tumor cell is CD33; (ii) a second domain, wherein said second domain is formed by an IgG Fc domain that specifically binds to a cell surface molecule at the cell surface of an immune cell, wherein said cell surface molecule at the cell surface of the immune cell is CD16, CD32a or CD64; and (iii) a third domain, wherein said third domain is formed by one or more SirpIg domains that specifically bind to a checkpoint molecule at the cell surface of said tumor cell, wherein said checkpoint molecule at the cell surface of said tumor cell is CD47.
A delivery device for delivering an implant to a target site, the delivery device comprising: a core member defining a proximal end and a distal end ; an outer winding defining a proximal end and a distal end , the outer winding surrounding and fixed to the core member, the outer winding extending between the proximal end of the core member and the distal end of the core member, the outer winding configured for displacement within a delivery catheter; and a coupling member at the distal end of the core member configured to releasably attach to an implant, wherein proximal and distal ends of the core member are respectively fixedly attached to proximal and distal ends of the outer winding, and respective distal ends of the core member and the outer winding are fixedly attached to the coupling member , such that a torque applied to a proximal end of the delivery device is transmitted to the coupling member to allow the coupling member to be detached from, or attached to, the implant. a core member defining a proximal end and a distal end ; an outer winding defining a proximal end and a distal end , the outer winding surrounding and fixed to the core member, the outer winding extending between the proximal end of the core member and the distal end of the core member, the outer winding configured for displacement within a delivery catheter; and a coupling member at the distal end of the core member configured to releasably attach to an implant, wherein proximal and distal ends of the core member are respectively fixedly attached to proximal and distal ends of the outer winding, and respective distal ends of the core member and the outer winding are fixedly attached to the coupling member , such that a torque applied to a proximal end of the delivery device is transmitted to the coupling member to allow the coupling member to be detached from, or attached to, the implant.
Data interruption device between a plurality of control units communicating through at least one communication protocol , characterized in that it is designed to produce an electromagnetic interference inhibiting a data communication between said plurality of control units , said device being equipped with at least one transformer designed to transfer at least one signal on at least one transmission means of said communication protocol , inducing said electromagnetic interference.
A working machine comprising: a ground engaging structure provided in the form of front and rear wheels or a pair of endless tracks; a body supported on the ground engaging structure ; a first working arm connected to the body for performing work functions, the first working arm comprising a first implement mount at a distal end thereof; a second implement mount connected to the body ; a milling device mounted to the second implement mount and configured to break up a surface, in use; and an apparatus mounted to the first implement mount for removing material from the surface, the apparatus comprising a collector having a first opening , and a sweeper trailing the collector in a preferred direction of operation of the apparatus , wherein the sweeper is configured and arranged to move surface material broken up by the milling device into the collector via the first opening . a ground engaging structure provided in the form of front and rear wheels or a pair of endless tracks; a body supported on the ground engaging structure ; a first working arm connected to the body for performing work functions, the first working arm comprising a first implement mount at a distal end thereof; a second implement mount connected to the body ; a milling device mounted to the second implement mount and configured to break up a surface, in use; and an apparatus mounted to the first implement mount for removing material from the surface, the apparatus comprising a collector having a first opening , and a sweeper trailing the collector in a preferred direction of operation of the apparatus , wherein the sweeper is configured and arranged to move surface material broken up by the milling device into the collector via the first opening .
Tool management system for coordinating and monitoring the use of at least a plurality of tools , in particular portable electric tools, wherein the tool management system comprises a user control system, which has: • user terminals for providing user data that identifies a user who wishes to use one of the tools , • data reception units in the tools for receiving the user data provided by the user terminals , • at least one data processing unit , which is designed to assign the user data received by one of the data reception units to one of a plurality of predefined user groups, stored in a memory unit , with different usage rights for the operation of the corresponding tool , wherein the tool management system has a central computer unit and a data transmission system and is designed to transmit data at least relating to users and/or usage rights and to transmit tool data identifying the tools between the central computer unit and the tools that are provided with the data reception units via the data transmission system , characterized in that the tool management system further comprises: • equipment-securing devices in at least some of the tools , wherein the equipment-securing devices and each comprise a safety mechanism for avoiding dangerous operating situations when using the tool and are designed such that they generate an alarm signal in the case of an accident detected with the aid of sensors and transmit said alarm signal via the data transmission system to the central computer unit , and the tool management system is designed to transmit the alarm signals via the data transmission system to further tools that are provided with data reception units . • user terminals for providing user data that identifies a user who wishes to use one of the tools , • data reception units in the tools for receiving the user data provided by the user terminals , • at least one data processing unit , which is designed to assign the user data received by one of the data reception units to one of a plurality of predefined user groups, stored in a memory unit , with different usage rights for the operation of the corresponding tool , wherein the tool management system has a central computer unit and a data transmission system and is designed to transmit data at least relating to users and/or usage rights and to transmit tool data identifying the tools between the central computer unit and the tools that are provided with the data reception units via the data transmission system , • equipment-securing devices in at least some of the tools , wherein the equipment-securing devices and each comprise a safety mechanism for avoiding dangerous operating situations when using the tool and are designed such that they generate an alarm signal in the case of an accident detected with the aid of sensors and transmit said alarm signal via the data transmission system to the central computer unit , and the tool management system is designed to transmit the alarm signals via the data transmission system to further tools that are provided with data reception units .
- Electric system comprising a light unit and a textile electrically conductive band , said light unit comprising at least a light source and electric connection means suitable for connecting said light unit to an electric power source, wherein said light unit comprises a supporting surface for said textile electrically conductive band and retention means for retaining said textile electrically conductive band on said supporting surface , said electric connection means comprising piercing means for piercing said textile electrically conductive band , wherein said piercing means are suitable for conducting an electric current; characterized in that said piercing means comprise two sets of needles emerging from said supporting surface and in that said textile electrically conductive band is made of double weaving and comprises two mutually parallel electrically conductive guides extending along said textile electrically conductive band, each of said electrically conductive guides being located between two layers of textile material of said double weaving and being formed by a plurality of metal threads which do not have any insulating covering.
End group-functionalized polymers, characterized in that the polymers have, at the end of the chain, a silane-containing carbinol group of the formula (I) where R 1 , R 2 are the same or different and are each alkyl and aryl radicals, R 3 , R 4 are the same or different and are each an H, alkyl, cycloalkyl, aryl, alkaryl and aralkyl radicals which may contain heteroatoms such as O, N, S, Si, A is a divalent organic radical which, as well as C and H, may contain heteroatoms such as O, N, S, Si, wherein the polymers are diene polymers or diene copolymers obtainable by copolymerization of dienes with vinylaromatic monomers. R 1 , R 2 are the same or different and are each alkyl and aryl radicals, R 3 , R 4 are the same or different and are each an H, alkyl, cycloalkyl, aryl, alkaryl and aralkyl radicals which may contain heteroatoms such as O, N, S, Si, A is a divalent organic radical which, as well as C and H, may contain heteroatoms such as O, N, S, Si, wherein the polymers are diene polymers or diene copolymers obtainable by copolymerization of dienes with vinylaromatic monomers.