Method of assembling a structure in aircraft or spacecraft production, comprising: providing at least two components to be joined to each other at a joint in order to form a structural assembly , each of the components comprising a joining region ; applying sealant to at least one of the components in the joining region thereof; forming an arrangement by positioning the components relative to each other, whereby an uncured layer of the sealant is formed between associated joining regions ; clamping the associated joining regions against each other to achieve a clamped state using at least one clamping device (155a-155g) and maintaining the clamped state of the associated joining regions at least until the layer of sealant therebetween and contacting the associated joining regions has cured to a pre-defined degree, the clamping device (155a-155e) being installable on and transportable along with the arrangement ; and after the layer of sealant has cured at least to the pre-defined degree, performing drilling at at least a plurality (205; 205, 206) of fastening positions (105; 105, 106) within the joining regions in order to obtain a hole (135; 135, 136) of final dimension at each of the plurality of fastening positions (105; 105, 106), and performing installation of a final fastener (145; 145, 146) at each of the fastening positions (105; 105, 106), characterised in that the moment at which the sealant has cured to a pre-defined degree corresponds to a curing degree in which the sealant does not flow anymore and without external mechanical effect the joining regions with the sealant in the pre-defined degree of curing inbetween remain unchanged in terms of their spatial arrangement relative to each other. providing at least two components to be joined to each other at a joint in order to form a structural assembly , each of the components comprising a joining region ; applying sealant to at least one of the components in the joining region thereof; forming an arrangement by positioning the components relative to each other, whereby an uncured layer of the sealant is formed between associated joining regions ; clamping the associated joining regions against each other to achieve a clamped state using at least one clamping device (155a-155g) and maintaining the clamped state of the associated joining regions at least until the layer of sealant therebetween and contacting the associated joining regions has cured to a pre-defined degree, the clamping device (155a-155e) being installable on and transportable along with the arrangement ; and after the layer of sealant has cured at least to the pre-defined degree, performing drilling at at least a plurality (205; 205, 206) of fastening positions (105; 105, 106) within the joining regions in order to obtain a hole (135; 135, 136) of final dimension at each of the plurality of fastening positions (105; 105, 106), and performing installation of a final fastener (145; 145, 146) at each of the fastening positions (105; 105, 106), characterised in that the moment at which the sealant has cured to a pre-defined degree corresponds to a curing degree in which the sealant does not flow anymore and without external mechanical effect the joining regions with the sealant in the pre-defined degree of curing inbetween remain unchanged in terms of their spatial arrangement relative to each other. <EOS>