A compound having the structure: wherein R 1 , R 2 , R 3 , R 4 , and R 5 are each independently H, halogen, CF 3 or C 1 -C 4 alkyl, wherein two or more of R 1 , R 2 , R 3 , R 4 , or R 5 are other than H; R 6 is H, or halogen; and B has the structure: wherein n is an integer from 0-1; α, β, χ, δ, ε, and φ are each independently absent or present, and when present each is a bond; Z 1 is N; Z 2 is N or NR 7 ; wherein R 7 is H, C 1 -C 4 alkyl, or oxetane; X is C or N; Y 1 , Y 2 , Y 3 , and Y 4 are each independently CR 8 , CH 2 , N, or N-R 9 , wherein R 8 is H, halogen, OCH 3 , CN, or CF 3 ; and R 9 is H, CN, oxetane, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, (C 1 -C 4 alkyl)(C 3 -C 6 cycloalkyl), (C 1 -C 6 alkyl)-OCH 3 , (C 1 -C 6 alkyl)-CF 3 , C(O)-(C 1 -C 6 alkyl), C(O) 2 -(C 1 -C 6 alkyl), C(O)-NH 2 , C(O)NH-(C 1 -C 6 alkyl), C(O)-(C 6 aryl), C(O)-(C 6 heteroaryl), C(O)-pyrrolidine, C(O)-piperidine, C(O)-piperazine, (C 1 -C 6 alkyl)-CO 2 H, (C 1 -C 6 alkyl)-CO 2 (C 1 -C 6 alkyl) or SO 2 -(C 1 -C 6 alkyl), wherein when R 1 is CF 3 , R 2 is H, R 3 is F, R 4 is H, and R 5 is H, or R 1 is H, R 2 is CF 3 , R 3 is H, R 4 is CF 3 , and R 5 is H, or R 1 is Cl, R 2 is H, R 3 is H, R 4 is F, and R 5 is H, or R 1 is CF 3 , R 2 is H, R 3 is F, R 4 is H, and R 5 is H, or R 1 is CF 3 , R 2 is F, R 3 is H, R 4 is H, and R 5 is H, or R 1 is Cl, R 2 is F, R 3 is H, R 4 is H, and R 5 is H, then B is other than or a pharmaceutically acceptable salt thereof. R 1 , R 2 , R 3 , R 4 , and R 5 are each independently H, halogen, CF 3 or C 1 -C 4 alkyl, wherein two or more of R 1 , R 2 , R 3 , R 4 , or R 5 are other than H; R 6 is H, or halogen; and B has the structure: wherein n is an integer from 0-1; α, β, χ, δ, ε, and φ are each independently absent or present, and when present each is a bond; Z 1 is N; Z 2 is N or NR 7 ; wherein R 7 is H, C 1 -C 4 alkyl, or oxetane; X is C or N; Y 1 , Y 2 , Y 3 , and Y 4 are each independently CR 8 , CH 2 , N, or N-R 9 , wherein R 8 is H, halogen, OCH 3 , CN, or CF 3 ; and R 9 is H, CN, oxetane, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, (C 1 -C 4 alkyl)(C 3 -C 6 cycloalkyl), (C 1 -C 6 alkyl)-OCH 3 , (C 1 -C 6 alkyl)-CF 3 , C(O)-(C 1 -C 6 alkyl), C(O) 2 -(C 1 -C 6 alkyl), C(O)-NH 2 , C(O)NH-(C 1 -C 6 alkyl), C(O)-(C 6 aryl), C(O)-(C 6 heteroaryl), C(O)-pyrrolidine, C(O)-piperidine, C(O)-piperazine, (C 1 -C 6 alkyl)-CO 2 H, (C 1 -C 6 alkyl)-CO 2 (C 1 -C 6 alkyl) or SO 2 -(C 1 -C 6 alkyl), n is an integer from 0-1; α, β, χ, δ, ε, and φ are each independently absent or present, and when present each is a bond; Z 1 is N; Z 2 is N or NR 7 ; wherein R 7 is H, C 1 -C 4 alkyl, or oxetane; X is C or N; Y 1 , Y 2 , Y 3 , and Y 4 are each independently CR 8 , CH 2 , N, or N-R 9 , wherein R 8 is H, halogen, OCH 3 , CN, or CF 3 ; and R 9 is H, CN, oxetane, C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, (C 1 -C 4 alkyl)(C 3 -C 6 cycloalkyl), (C 1 -C 6 alkyl)-OCH 3 , (C 1 -C 6 alkyl)-CF 3 , C(O)-(C 1 -C 6 alkyl), C(O) 2 -(C 1 -C 6 alkyl), C(O)-NH 2 , C(O)NH-(C 1 -C 6 alkyl), C(O)-(C 6 aryl), C(O)-(C 6 heteroaryl), C(O)-pyrrolidine, C(O)-piperidine, C(O)-piperazine, (C 1 -C 6 alkyl)-CO 2 H, (C 1 -C 6 alkyl)-CO 2 (C 1 -C 6 alkyl) or SO 2 -(C 1 -C 6 alkyl), wherein when R 1 is CF 3 , R 2 is H, R 3 is F, R 4 is H, and R 5 is H, or R 1 is H, R 2 is CF 3 , R 3 is H, R 4 is CF 3 , and R 5 is H, or R 1 is Cl, R 2 is H, R 3 is H, R 4 is F, and R 5 is H, or R 1 is CF 3 , R 2 is H, R 3 is F, R 4 is H, and R 5 is H, or R 1 is CF 3 , R 2 is F, R 3 is H, R 4 is H, and R 5 is H, or R 1 is Cl, R 2 is F, R 3 is H, R 4 is H, and R 5 is H, then B is other than or a pharmaceutically acceptable salt thereof. <EOS>