mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of formula (I) wherein each R 1 is independently selected from the group consisting of halogen, -CN, -CF 3 , -OCF 3 , C 1-3 alkyl and C 1-3 alkoxy; t is 0, 1 or 2; ring A is selected from the group consisting of C 4-7 cycloalkylene, C 4-7 cycloalkenylene and 4-7 membered nitrogen-containing heterocyclylene, wherein said C 4-7 cycloalkylene, C 4-7 cycloalkenylene and 4-7 membered nitrogen-containing heterocyclylene is optionally substituted with one or more, identical or different substituent(s) selected from the group consisting of halogen, C 1-4 alkyl and oxo; G is selected from the group consisting of a bond, -NH-, -N(C 1-4 alkyl)- and -O-; LK is -U-V-W-, wherein U binds to G ; U is selected from the group consisting of a bond, carbonyl, C 1-12 alkylene, C 6-10 arylene, 5-10 membered heteroarylene, -(CH 2 ) n O- and -O(CH 2 ) n -; V is selected from the group consisting of a bond, carbonyl, C 1-12 alkylene, C 6-10 arylene, 5-10 membered heteroarylene, -(CH 2 ) n O- and -O(CH 2 ) n -; W is selected from the group consisting of a bond, carbonyl, C 1-12 alkylene, C 6-10 arylene, 5-10 membered heteroarylene, -(CH 2 ) n O- and -O(CH 2 ) n -; wherein each of said C 6-10 arylene and of said 5-10 membered heteroarylene in U, V and W is optionally independently substituted with one to three, identical or different substituent(s) selected from the group consisting of halogen, C 1-4 alkyl, C 1-4 alkoxy and -CN; wherein at least one of U , V and W is different from the other two; wherein U and W are not -O- if V is -O-; each n is independently selected from 0 to 8; or a salt thereof. each R 1 is independently selected from the group consisting of halogen, -CN, -CF 3 , -OCF 3 , C 1-3 alkyl and C 1-3 alkoxy; t is 0, 1 or 2; ring A is selected from the group consisting of C 4-7 cycloalkylene, C 4-7 cycloalkenylene and 4-7 membered nitrogen-containing heterocyclylene, wherein said C 4-7 cycloalkylene, C 4-7 cycloalkenylene and 4-7 membered nitrogen-containing heterocyclylene is optionally substituted with one or more, identical or different substituent(s) selected from the group consisting of halogen, C 1-4 alkyl and oxo; G is selected from the group consisting of a bond, -NH-, -N(C 1-4 alkyl)- and -O-; LK is -U-V-W-, wherein U binds to G ; U is selected from the group consisting of a bond, carbonyl, C 1-12 alkylene, C 6-10 arylene, 5-10 membered heteroarylene, -(CH 2 ) n O- and -O(CH 2 ) n -; V is selected from the group consisting of a bond, carbonyl, C 1-12 alkylene, C 6-10 arylene, 5-10 membered heteroarylene, -(CH 2 ) n O- and -O(CH 2 ) n -; W is selected from the group consisting of a bond, carbonyl, C 1-12 alkylene, C 6-10 arylene, 5-10 membered heteroarylene, -(CH 2 ) n O- and -O(CH 2 ) n -; wherein each of said C 6-10 arylene and of said 5-10 membered heteroarylene in U, V and W is optionally independently substituted with one to three, identical or different substituent(s) selected from the group consisting of halogen, C 1-4 alkyl, C 1-4 alkoxy and -CN; wherein at least one of U , V and W is different from the other two; wherein U and W are not -O- if V is -O-; each n is independently selected from 0 to 8; or a salt thereof.
Connection profile for components , like window casings or door frames, jambs, roller shutters or the like, adjoining plasterwork, having a plaster leg on which the plasterwork comes into contact, and a retaining leg connecting to the plaster leg , and a sealing strip which is fixed to the retaining leg and with which the connection profile can be fixed to the component , characterized in that a front sealing leg , which is connected to the plaster leg via a sealing strap , is attached to the sealing strip , and the retaining leg comprises a rear sealing leg which lies behind the front sealing leg when viewed from the plaster leg and is attached to the sealing strip , wherein, upon reaching a predetermined tensile force, the rear sealing leg detaches from the sealing strip and the front sealing leg remains arranged on the sealing strip .
A method of operation of a terminal device, comprising: obtaining location information relating to a location of the terminal device, wherein the location information comprises first location information and second location information, wherein the first location information relates to a location of the terminal device within a region and the first location information identifies a cell within the region, and wherein the second location information identifies the region in which the terminal device is located; forming content for a proximity service discovery message, wherein the content for the proximity service discovery message includes the first location information; calculating a message integrity code based on the content for the proximity service discovery message and the second location information; and transmitting the proximity service discovery message, comprising the content for the proximity service discovery message and the computed message integrity code. obtaining location information relating to a location of the terminal device, wherein the location information comprises first location information and second location information, wherein the first location information relates to a location of the terminal device within a region and the first location information identifies a cell within the region, and wherein the second location information identifies the region in which the terminal device is located; forming content for a proximity service discovery message, wherein the content for the proximity service discovery message includes the first location information; calculating a message integrity code based on the content for the proximity service discovery message and the second location information; and transmitting the proximity service discovery message, comprising the content for the proximity service discovery message and the computed message integrity code.
A method of performing a de novo enzymatic synthesis using digital microfluidics (DMF), the method comprising: placing a cartridge having at least one substrate within an air gap of the cartridge, so that a hydrophobic base of the cartridge is in electrical contact with an array of drive electrodes in the DMF apparatus, wherein a plurality of polynucleotide initiator fragments are tethered to the at least one substrate; applying power to the drive electrodes to individually move a series of droplets over the substrate by electrowetting in order to repeat the process of: (a) passing a droplet comprising an enzymatic mix including a single dNTP type over the at least one substrate comprising the plurality of polynucleotide initiator fragments; (b) incubating a droplet on the at least one substrate to add one of the single dNTP type to an end of the polynucleotide initiator fragments; (c) removing the droplet from the at least one substrate; wherein steps (a)-(c) are repeated to synthesize a polynucleotide. placing a cartridge having at least one substrate within an air gap of the cartridge, so that a hydrophobic base of the cartridge is in electrical contact with an array of drive electrodes in the DMF apparatus, wherein a plurality of polynucleotide initiator fragments are tethered to the at least one substrate; applying power to the drive electrodes to individually move a series of droplets over the substrate by electrowetting in order to repeat the process of: (a) passing a droplet comprising an enzymatic mix including a single dNTP type over the at least one substrate comprising the plurality of polynucleotide initiator fragments; (b) incubating a droplet on the at least one substrate to add one of the single dNTP type to an end of the polynucleotide initiator fragments; (c) removing the droplet from the at least one substrate; (a) passing a droplet comprising an enzymatic mix including a single dNTP type over the at least one substrate comprising the plurality of polynucleotide initiator fragments; (b) incubating a droplet on the at least one substrate to add one of the single dNTP type to an end of the polynucleotide initiator fragments; (c) removing the droplet from the at least one substrate; wherein steps (a)-(c) are repeated to synthesize a polynucleotide.
Household refrigeration appliance with an interior , which is limited by walls of an inner container , wherein in the interior a displaceable support carriage is arranged, which is embodied for receiving at least one container for foodstuffs, and a guide apparatus is embodied, to which the support carriage is connected and with which the support carriage is guided in its movement in the depth direction of the interior , wherein the support carriage , in a rear region viewed in the depth direction of the household refrigeration appliance , has a recess which is embodied for coupling to a coupling element on the container in such a manner that the container is motion-coupled with the support carriage in the depth direction, characterised in that the support carriage has rollers (16 to 19), with which it can be displaced in the interior , and that the support carriage is a movable tray, and that the guide apparatus is embodied on a plate arranged below the support carriage , wherein the plate is arranged on opposite side walls of the inner container .
Method for tracking the in-vitro amplification of a nucleotide sequence contained in a sample, the amplification aiming to replicate the nucleotide sequence via a polymerase DNA enzyme, the amplification being loop-mediated isothermal amplification, also known by its acronym LAMP, the method including the following steps: a) mixing the sample with a reaction medium that is apt to obtain multiple replications of a preset nucleotide sequence called the target sequence, the mixing being carried out at an initial time ( t 0 ); b) illuminating the sample using a point light source , the light source emitting, in an illumination spectral band, an incident light wave that propagates towards the sample; c) acquiring, using an image sensor , a two-dimensional image ( I 0 ) of the sample, the sample being placed between the light source and the image sensor such that the image sensor is exposed to what is called an exposure light wave having passed through the sample, the acquisition being carried out at an acquisition time ( t ) subsequent to the initial time; d) on the basis of the acquired image ( I 0 ), forming an image of interest ( I 0 , ROI, I Z ) that is representative of the formation of a precipitate (10 p ) in the sample under the effect of the amplification; and e) determining an indicator (k, k(t)), called the amplification indicator, depending on a distribution of the intensity of the pixels in all or some of the image of interest, the amplification indicator being representative of a replicated amount of target sequences; the method being characterized in that , in step c), the two-dimensional image of the sample is acquired in the illumination spectral band and in that , in step e), the amplification indicator is determined depending on a dispersion of the intensity of the pixels in the image of interest. a) mixing the sample with a reaction medium that is apt to obtain multiple replications of a preset nucleotide sequence called the target sequence, the mixing being carried out at an initial time ( t 0 ); b) illuminating the sample using a point light source , the light source emitting, in an illumination spectral band, an incident light wave that propagates towards the sample; c) acquiring, using an image sensor , a two-dimensional image ( I 0 ) of the sample, the sample being placed between the light source and the image sensor such that the image sensor is exposed to what is called an exposure light wave having passed through the sample, the acquisition being carried out at an acquisition time ( t ) subsequent to the initial time; d) on the basis of the acquired image ( I 0 ), forming an image of interest ( I 0 , ROI, I Z ) that is representative of the formation of a precipitate (10 p ) in the sample under the effect of the amplification; and e) determining an indicator (k, k(t)), called the amplification indicator, depending on a distribution of the intensity of the pixels in all or some of the image of interest, the amplification indicator being representative of a replicated amount of target sequences;
A process for producing methanol, which process comprises contacting H 2 and CO 2 with a solid catalyst, at a temperature of from 200 °C to 300 °C and at a reactant pressure of from 150 bar to 500 bar, which reactant pressure is the sum of the partial pressures of the H 2 and the CO 2 , wherein: the molar ratio of the H 2 to the CO 2 is x:1.0, wherein x is from 2.5 to 3.5; and the catalyst comprises (i) a copper component which is Cu, CuO or Cu 2 O, or a mixture of two or three thereof, and (ii) ZnO, wherein the catalyst has a specific copper surface area (S Cu ) of at least 10 m 2 /g-catalyst. the molar ratio of the H 2 to the CO 2 is x:1.0, wherein x is from 2.5 to 3.5; and the catalyst comprises (i) a copper component which is Cu, CuO or Cu 2 O, or a mixture of two or three thereof, and (ii) ZnO, wherein the catalyst has a specific copper surface area (S Cu ) of at least 10 m 2 /g-catalyst.
A vehicle control system mounted on a vehicle , the system being configured to; detect an object external to the vehicle , determine a two-dimensional speed distribution area around the object extending at least in a lateral area of the object in a travelling direction of the vehicle as well as in a rearward area and/or a forward area of the object , and defining a distribution of an allowable upper limit (V lim ) of a relative speed of the vehicle with respect to the object in the travelling direction of the vehicle, wherein the allowable upper limit (V lim ) is defined at respective points in the speed distribution area according to the distance from the object , and execute an avoidance control for restricting the relative speed of the vehicle with respect to the object so that the relative speed does not exceed the allowable upper limit (V lim ) in the speed distribution area . detect an object external to the vehicle , determine a two-dimensional speed distribution area around the object extending at least in a lateral area of the object in a travelling direction of the vehicle as well as in a rearward area and/or a forward area of the object , and defining a distribution of an allowable upper limit (V lim ) of a relative speed of the vehicle with respect to the object in the travelling direction of the vehicle, wherein the allowable upper limit (V lim ) is defined at respective points in the speed distribution area according to the distance from the object , and execute an avoidance control for restricting the relative speed of the vehicle with respect to the object so that the relative speed does not exceed the allowable upper limit (V lim ) in the speed distribution area .
A method performed by a User Equipment, UE , for power saving operations, the method comprising: receiving a first Radio Resource Control, RRC, configuration indicating a set of one or more dormancy cell groups , wherein a group of serving cells belongs to a specific dormancy cell group in the set of one or more dormancy cell groups ; receiving a second RRC configuration indicating a first Bandwidth Part, BWP, on which the UE is configured with a dormant operation, for a serving cell , the dormant operation including performing a Channel State Information, CSI, measurement and stopping monitoring a Physical Downlink Control Channel, PDCCH, the serving cell 802, 804, 806, 808) belonging to the group of serving cells ; receiving a third RRC configuration indicating a second BWP, on which the UE is not configured with the dormant operation, for the serving cell; receiving a Power Saving Signal, PSS , on a Primary Cell, PCell, or a Special Cell, SpCell, when the UE is not in a Discontinuous Reception, DRX, active time , wherein the PSS includes a bitmap, and each bit (B1, B2) in the bitmap is associated with one dormancy cell group in the set of one or more dormancy cell groups ; determining an active BWP of the serving cell included in the group of serving cells as the first BWP after determining that a bit (B1, B2) associated with the specific dormancy cell group in the bitmap is set to a first value; and determining the active BWP of the serving cell as the second BWP after determining that the bit (B1, B2) is set to a second value. receiving a first Radio Resource Control, RRC, configuration indicating a set of one or more dormancy cell groups , wherein a group of serving cells belongs to a specific dormancy cell group in the set of one or more dormancy cell groups ; receiving a second RRC configuration indicating a first Bandwidth Part, BWP, on which the UE is configured with a dormant operation, for a serving cell , the dormant operation including performing a Channel State Information, CSI, measurement and stopping monitoring a Physical Downlink Control Channel, PDCCH, the serving cell 802, 804, 806, 808) belonging to the group of serving cells ; receiving a third RRC configuration indicating a second BWP, on which the UE is not configured with the dormant operation, for the serving cell; receiving a Power Saving Signal, PSS , on a Primary Cell, PCell, or a Special Cell, SpCell, when the UE is not in a Discontinuous Reception, DRX, active time , wherein the PSS includes a bitmap, and each bit (B1, B2) in the bitmap is associated with one dormancy cell group in the set of one or more dormancy cell groups ; determining an active BWP of the serving cell included in the group of serving cells as the first BWP after determining that a bit (B1, B2) associated with the specific dormancy cell group in the bitmap is set to a first value; and determining the active BWP of the serving cell as the second BWP after determining that the bit (B1, B2) is set to a second value.
Wind turbine rotor blade having a blade outer side , a wall , a blade inner side , and at least a first and second rotor blade portion which are secured to each other by means of at least one securing unit in a dividing plane , wherein the wall has in the region of the first rotor blade portion a laminate having at least a first through-hole , wherein the wall has in the region of the second rotor blade portion a laminate having at least a second through-hole , wherein the at least one securing unit has a cable having a first end and second end and a tensioning element which is coupled to the first and second end of the cable and which is configured to pretension the cable , wherein the first end and second end of the cable and the tensioning element are arranged at the rotor blade inner side , wherein the cable is guided through the first and second through-holes , wherein the at least one securing unit has transverse pins in the first and second through-holes , wherein the transverse pins serve to redirect the cable in the first and second through-holes so that a portion of the cable abuts the rotor blade outer side and the first and second ends of the cable are provided on the rotor blade inner side . a blade outer side , a wall , a blade inner side , and at least a first and second rotor blade portion which are secured to each other by means of at least one securing unit in a dividing plane , wherein the wall has in the region of the first rotor blade portion a laminate having at least a first through-hole , wherein the wall has in the region of the second rotor blade portion a laminate having at least a second through-hole , wherein the at least one securing unit has a cable having a first end and second end and a tensioning element which is coupled to the first and second end of the cable and which is configured to pretension the cable , wherein the first end and second end of the cable and the tensioning element are arranged at the rotor blade inner side , wherein the cable is guided through the first and second through-holes , wherein the at least one securing unit has transverse pins in the first and second through-holes , wherein the transverse pins serve to redirect the cable in the first and second through-holes so that a portion of the cable abuts the rotor blade outer side and the first and second ends of the cable are provided on the rotor blade inner side .
A computing device for managing data elements in a cloud computing environment comprising: a communication module configured to transmit and receive data elements ; and a cloud data manager , coupled to the communication module, configured to facilitate the cloud computing environment to manage data elements in the cloud computing environment in accordance with management policies stored in management metadata associated with the data elements, wherein the management policies require that the data elements be encrypted, wherein the management metadata comprises trace metadata configured to track transmission of the data elements, wherein the management policies govern whether the data elements may be transmitted to a server (C2B) of the cloud computing environment that is located in a controlled country comprising a prevention of transmission if the data element would not be encrypted during transmission to the server (C2B) of the cloud computing environment that is located in the controlled country. a communication module configured to transmit and receive data elements ; and a cloud data manager , coupled to the communication module, configured to facilitate the cloud computing environment to manage data elements in the cloud computing environment in accordance with management policies stored in management metadata associated with the data elements, wherein the management policies require that the data elements be encrypted, wherein the management metadata comprises trace metadata configured to track transmission of the data elements, wherein the management policies govern whether the data elements may be transmitted to a server (C2B) of the cloud computing environment that is located in a controlled country comprising a prevention of transmission if the data element would not be encrypted during transmission to the server (C2B) of the cloud computing environment that is located in the controlled country.
An immune effector cell ( e.g. a population of immune effector cells), comprising: (a) a first chimeric antigen receptor (CAR) molecule or nucleic acid encoding the same, wherein said first CAR molecule is a CAR polypeptide comprising an antigen binding domain, a transmembrane domain, and an intracellular signaling domain comprising a costimulatory domain and/or a primary signaling domain, and wherein said antigen binding domain comprises a VHH domain and binds to a tumor antigen; and (b) a second CAR molecule or nucleic acid encoding the same, wherein said second CAR molecule is a CAR polypeptide having an antigen binding domain comprising an scFv. (a) a first chimeric antigen receptor (CAR) molecule or nucleic acid encoding the same, wherein said first CAR molecule is a CAR polypeptide comprising an antigen binding domain, a transmembrane domain, and an intracellular signaling domain comprising a costimulatory domain and/or a primary signaling domain, and wherein said antigen binding domain comprises a VHH domain and binds to a tumor antigen; and (b) a second CAR molecule or nucleic acid encoding the same, wherein said second CAR molecule is a CAR polypeptide having an antigen binding domain comprising an scFv.
A sealing element for sealing a housing opening in a housing , wherein the sealing element has at least one passage opening for the leading through of an electrical line into the housing, the sealing element is formed by a first part element and a second part element , wherein the first part element is at least partly covered by the second part element , wherein the first part element and the second part element have a different hardness, wherein the first part element has a greater hardness than the second part element , characterized in that both part elements are composed of silicone, with the first part element and the second part element being non-releasably connected to one another.