mhurhangee/patent-ind-claim-en huggingface dataset:
A combination medicament, comprising - an IL-12 polypeptide, or a nucleic acid expression vector comprising a sequence encoding said IL-12 polypeptide, and - a non-agonist ligand selected from the group consisting of an antibody, an antibody fragment, and an antibody-like molecule, wherein said non-agonist ligand is capable of binding to one of PD-1, PD-L1 or PD-L2 with a dissociation constant of at least 10 -7 M -1 , and wherein said non-agonist ligand is provided as a dosage form for systemic delivery, for use in the therapy of a malignant neoplastic disease, wherein - said IL-12 polypeptide, or said nucleic acid expression vector, is provided by administration into a tumour, into the vicinity of a tumour, or to the lymph node associated with a tumour. - an IL-12 polypeptide, or a nucleic acid expression vector comprising a sequence encoding said IL-12 polypeptide, and - a non-agonist ligand selected from the group consisting of an antibody, an antibody fragment, and an antibody-like molecule, wherein said non-agonist ligand is capable of binding to one of PD-1, PD-L1 or PD-L2 with a dissociation constant of at least 10 -7 M -1 , and wherein said non-agonist ligand is provided as a dosage form for systemic delivery, - said IL-12 polypeptide, or said nucleic acid expression vector, is provided by administration into a tumour, into the vicinity of a tumour, or to the lymph node associated with a tumour.
A laminated polyester film comprising: a polyester film and a coating layer which is formed on at least one surface of the polyester film and is produced by applying a coating solution comprising a polyester resin having a naphthalene skeleton, a metal oxide, and two or more kinds of crosslinking agents, thereonto, wherein the two or more kinds of crosslinking agents comprise an isocyanate compound and an oxazoline compound. a polyester film and a coating layer which is formed on at least one surface of the polyester film and is produced by applying a coating solution comprising a polyester resin having a naphthalene skeleton, a metal oxide, and two or more kinds of crosslinking agents, thereonto, wherein the two or more kinds of crosslinking agents comprise an isocyanate compound and an oxazoline compound.
A semiconductor device comprising: a semiconductor substrate; a first coil formed on the semiconductor substrate via a first insulation film; a second insulation film formed on the semiconductor substrate so as to cover the first insulation film and the first coil; a first pad formed on the second insulation film and disposed at a position not overlapped with the first coil in a planar view; a laminated insulation film formed on the second insulation film, the laminated insulation film having a first opening from which the first pad is exposed; a second coil formed on the laminated insulation film and disposed above the first coil; and a first wiring formed on the laminated insulation film including an upper portion of the first pad exposed from the first opening, the first wiring being electrically connected to the first pad, wherein the laminated insulation film is composed of a silicon oxide film, a silicon nitride film on the silicon oxide film, and a resin film on the silicon nitride film, the first coil and the second coil are not connected by a conductor but magnetically coupled to each other, and a part of the first pad is covered by the laminated insulation film. a semiconductor substrate; a first coil formed on the semiconductor substrate via a first insulation film; a second insulation film formed on the semiconductor substrate so as to cover the first insulation film and the first coil; a first pad formed on the second insulation film and disposed at a position not overlapped with the first coil in a planar view; a laminated insulation film formed on the second insulation film, the laminated insulation film having a first opening from which the first pad is exposed; a second coil formed on the laminated insulation film and disposed above the first coil; and a first wiring formed on the laminated insulation film including an upper portion of the first pad exposed from the first opening, the first wiring being electrically connected to the first pad, wherein the laminated insulation film is composed of a silicon oxide film, a silicon nitride film on the silicon oxide film, and a resin film on the silicon nitride film, the first coil and the second coil are not connected by a conductor but magnetically coupled to each other, and a part of the first pad is covered by the laminated insulation film.
1. Method for the optimized use of a parking area , wherein vehicles which are intended to be parked in the parking area are each allocated a parking space , wherein the vehicles head for the respectively allocated parking space , in particular autonomously, wherein the vehicles carry out a change of the parking space during the parking duration in order to enable improved use of the available parking area , characterized in that a plurality of vehicles are moved and an available range is determined for each vehicle involved in an operation, and a change of the parking space during the parking duration is carried out on the basis of the available range of the individual vehicles involved in the respective operation, wherein the available range of a vehicle is newly determined by means of a calculation model for determining the fuel consumption and/or the power consumption of the vehicle from a starting position until reaching the target point of a change of the parking space of the vehicle before and/or after a change of the parking space , wherein the calculation model is dependent on the vehicle type.
A carbene compound represented by the following Chemical Formula 1 or 2 substituted with polyethylene glycol (PEG) having nitrogen-containing functional groups at a terminal: wherein Chemical Formulas 1 and 2 above, R1, R2, R5 and R6 are equal to or different from each other, and each independently hydrogen, an alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 30 carbon atoms, or a heteroaryl group having 2 to 30 carbon atoms, R3, R4, R7, R8, R9 and R10 are equal to or different from each other, and each independently hydrogen, an alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 30 carbon atoms, a heteroaryl group having 2 to 30 carbon atoms, or a structure represented by the following Chemical 3, or two or more substituents adjacent to each other in R7 to R10 bind to form a hydrocarbon ring, at least one of R3 and R4 has a structure represented by the following Chemical Formula 3, at least one of R7 to R10 is a structure represented by the following Chemical Formula 3, or when two or more substituents adjacent to each other in R7 to R10 bind to form the hydrocarbon ring, at least one of hydrogens bound to carbons forming the hydrocarbon ring is substituted with a structure represented by the following Chemical Formula 3, in Chemical Formula 3 above, n is an integer of 1 to 30 as the number of repeated units in parentheses, and A is an alkyl group having 1 to 20 carbon atoms containing nitrogen (N) atoms or a heteroaryl group having 2 to 30 carbon atoms containing nitrogen (N) atoms. wherein Chemical Formulas 1 and 2 above, R1, R2, R5 and R6 are equal to or different from each other, and each independently hydrogen, an alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 30 carbon atoms, or a heteroaryl group having 2 to 30 carbon atoms, R3, R4, R7, R8, R9 and R10 are equal to or different from each other, and each independently hydrogen, an alkyl group having 1 to 20 carbon atoms, a cycloalkyl group having 3 to 20 carbon atoms, an aryl group having 6 to 30 carbon atoms, a heteroaryl group having 2 to 30 carbon atoms, or a structure represented by the following Chemical 3, or two or more substituents adjacent to each other in R7 to R10 bind to form a hydrocarbon ring, at least one of R3 and R4 has a structure represented by the following Chemical Formula 3, at least one of R7 to R10 is a structure represented by the following Chemical Formula 3, or when two or more substituents adjacent to each other in R7 to R10 bind to form the hydrocarbon ring, at least one of hydrogens bound to carbons forming the hydrocarbon ring is substituted with a structure represented by the following Chemical Formula 3, in Chemical Formula 3 above, n is an integer of 1 to 30 as the number of repeated units in parentheses, and A is an alkyl group having 1 to 20 carbon atoms containing nitrogen (N) atoms or a heteroaryl group having 2 to 30 carbon atoms containing nitrogen (N) atoms.
Computer implemented method for training an agent (AG1, AGn) for a method, wherein the agent (AG1, AGn) is trained by reinforcement learning to control a manufacturing schedule for manufacturing a product (1, n) based on an environment model (M100) of an industrial manufacturing environment , wherein an agent (AG1, AGn) corresponding to each product (1, n) is provided, the agent (AG1, AGn) comprising a neural network based actor (act1, actn) with actor-parameters, wherein training the agent (AG1, AGn) comprises the steps: - disabling machine objects (M10,...,M31) by the environment model (M100) randomly during training the agents (AG1, AGn), determining, by the actor (act1, actn), an action (a1, an) for the product (1, n) based on a product specific state observation (s1, sn), - determining, by the environment model (M100), an agent specific reward for the action (a1, an) and a global reward (GR) based on all agent specific rewards of all agents (AG1, AGn), - determining, by a neural network based critic (crit1, critn), an activation value based on a global state observation (GS), a global reward (GR) and a subsequent global state observation (GS+1), - updating the parameters of the actor (act1, actn) based on the activation value of the critic (crit1, critn). wherein an agent (AG1, AGn) corresponding to each product (1, n) is provided, the agent (AG1, AGn) comprising a neural network based actor (act1, actn) with actor-parameters, wherein training the agent (AG1, AGn) comprises the steps: - disabling machine objects (M10,...,M31) by the environment model (M100) randomly during training the agents (AG1, AGn), - disabling machine objects (M10,...,M31) by the environment model (M100) randomly during training the agents (AG1, AGn), determining, by the actor (act1, actn), an action (a1, an) for the product (1, n) based on a product specific state observation (s1, sn), - determining, by the environment model (M100), an agent specific reward for the action (a1, an) and a global reward (GR) based on all agent specific rewards of all agents (AG1, AGn), - determining, by a neural network based critic (crit1, critn), an activation value based on a global state observation (GS), a global reward (GR) and a subsequent global state observation (GS+1), - updating the parameters of the actor (act1, actn) based on the activation value of the critic (crit1, critn). - determining, by the environment model (M100), an agent specific reward for the action (a1, an) and a global reward (GR) based on all agent specific rewards of all agents (AG1, AGn), - determining, by a neural network based critic (crit1, critn), an activation value based on a global state observation (GS), a global reward (GR) and a subsequent global state observation (GS+1), - updating the parameters of the actor (act1, actn) based on the activation value of the critic (crit1, critn).
A wire for weaving or knitting a catalyst gauze, said wire being characterized in that it is a twisted wire comprising an assembly of n intertwined filaments, n being an integer with 2 ≤ n ≤ 8, wherein each of said filaments comprises at least 50% by weight of Pt, said filaments being twisted together over their length so that each of the filaments is wound to at least one other filament.
A fifth wheel coupling with a camera , comprising a coupling plate and a bearing element , with which the coupling plate can be secured to a towing vehicle, wherein the coupling plate has a centrally arranged locking region for receiving a king pin, as well as an insertion opening running along a longitudinal axis (x) and bordered on both sides by two insertion flanges , characterized in that, the camera being secured to the bearing element .
A method of wireless communication of audio/video, AV, information between AV devices, comprising: receiving audio/video, AV, information comprising audio data, video data and interface specific control data from a first AV module via a first wired AV interface in a first AV device, wherein a certain portion of the interface specific control data is transmitted in data islands during H/V blanking periods of HDMI frames and a certain other portion of the interface specific control data is transmitted via a separate interface such as I 2 C, inter-integrated circuit; performing interface dependent processing on the AV information that comprises separation of the audio data, the video data and the interface specific control data for a first AV interface type, and conversion of the interface specific control data, the audio data and the video data, wherein the interface specific control data is converted to interface-independent control information; converting a first packet format to a second packet format for packetizing the audio data, the video data and the interface-independent control information; and transmitting the audio data, the video data and the interface-independent control information in the second packet format from a wireless transceiver over a wireless channel to a wireless receiver of a second AV device including a second wired AV interface, wherein the first wired AV interface is of a different type to the second wired AV interface. receiving audio/video, AV, information comprising audio data, video data and interface specific control data from a first AV module via a first wired AV interface in a first AV device, wherein a certain portion of the interface specific control data is transmitted in data islands during H/V blanking periods of HDMI frames and a certain other portion of the interface specific control data is transmitted via a separate interface such as I 2 C, inter-integrated circuit; performing interface dependent processing on the AV information that comprises separation of the audio data, the video data and the interface specific control data for a first AV interface type, and conversion of the interface specific control data, the audio data and the video data, wherein the interface specific control data is converted to interface-independent control information; converting a first packet format to a second packet format for packetizing the audio data, the video data and the interface-independent control information; and transmitting the audio data, the video data and the interface-independent control information in the second packet format from a wireless transceiver over a wireless channel to a wireless receiver of a second AV device including a second wired AV interface, wherein the first wired AV interface is of a different type to the second wired AV interface.
A monitoring system comprising a manually operable user interface device coupled, at least intermittently, to a speech-to-text component and a text phrase parser component in combination to extract user speech keywords that match a list of preprogrammed and adaptive real-time security commands ,wherein the monitoring system is adapted to execute the commands, and wherein the adaptive real-time security command comprises a combination of at least one word from a pre-loaded database of fixed words and one real time adaptive word from a real time vocabulary list , wherein the monitoring system is adapted to add real time adaptive words to the real time vocabulary list by users typing or speaking the words to the user interface device .
A carbon fiber reinforced polymer laminate with a cane shape for strengthening a reinforced concrete beam with an axis or concrete slab with a slab plane, the beam or slab having stirrups embedment into the interior and a concrete cover, which beam or slab comprises grooves and holes for the insertion of said carbon fiber reinforced polymer laminate and high fluidity adhesive material, wherein the cane shape comprises two rectilinear segments (Ls, Lb) and one transition zone (Tz) connecting the two rectilinear segments (Ls, Lb), wherein the outer segment (Ls) forms an extremity of the cane shape of the carbon fiber reinforced polymer laminate, wherein in use the inclination of the extremity ranges between 30 to 90 degrees regarding the beam axis or the slab plane of the reinforced concrete beam or concrete slab to be reinforced respectively.
Beverage container comprising: - a cup with an inner wall which delimits a receiving space for liquid that is open on an upper side (O) of the cup , the cup further having an outer wall , wherein between the inner wall and the outer wall an open space is formed on the top (O) and - a lid , which is arranged removably on the top (O) of the cup in such a way that it closes a receiving space opening and an intermediate space opening in a fluid-tight manner, characterized in that - a sensor unit is arranged in the lid for detecting an amount of liquid removed from the cup by a user, and - the cover has a wireless communication unit which is set up to establish a data connection with a mobile terminal of the user and to transmit the detected amount of liquid to the user's mobile terminal for evaluation, and wherein - the lid has a lid flap and a folding mechanism on which the lid flap is pivotally mounted from a closed position to an open position and vice versa, and the folding mechanism and the wireless communication unit are formed such that the data connection with the mobile terminal is established when the lid flap is pivoted from the closed position to the open position. - a cup with an inner wall which delimits a receiving space for liquid that is open on an upper side (O) of the cup , the cup further having an outer wall , wherein between the inner wall and the outer wall an open space is formed on the top (O) and - a lid , which is arranged removably on the top (O) of the cup in such a way that it closes a receiving space opening and an intermediate space opening in a fluid-tight manner, characterized in that - a sensor unit is arranged in the lid for detecting an amount of liquid removed from the cup by a user, and - the cover has a wireless communication unit which is set up to establish a data connection with a mobile terminal of the user and to transmit the detected amount of liquid to the user's mobile terminal for evaluation, and wherein - the lid has a lid flap and a folding mechanism on which the lid flap is pivotally mounted from a closed position to an open position and vice versa, and the folding mechanism and the wireless communication unit are formed such that the data connection with the mobile terminal is established when the lid flap is pivoted from the closed position to the open position.
A vacuum pump comprising: a housing and a cooling element , the cooling element comprising: a base element , wherein by the base element an internal void is defined, an inlet connected to the base element and in fluid connection with the void and an outlet connected to the base element and in fluid connection with the void such that a coolant can flow from the inlet through the void to the outlet to dissipate heat, wherein the base element is connected to the housing of the vacuum pump, characterized in that the void has a flat shape such that the width of the void is more than twice as large as the height of the void , and the height of the void is less than 3mm; and in that the internal void comprises at least one corrugated surface to create turbulent flow within the void , wherein the at least one corrugated surface provides grooves or ribs which are arranged perpendicular to the direction of flow through the void . a housing and a cooling element , the cooling element comprising: a base element , wherein by the base element an internal void is defined, an inlet connected to the base element and in fluid connection with the void and an outlet connected to the base element and in fluid connection with the void such that a coolant can flow from the inlet through the void to the outlet to dissipate heat, wherein the base element is connected to the housing of the vacuum pump, a base element , wherein by the base element an internal void is defined, an inlet connected to the base element and in fluid connection with the void and an outlet connected to the base element and in fluid connection with the void such that a coolant can flow from the inlet through the void to the outlet to dissipate heat, wherein the base element is connected to the housing of the vacuum pump, characterized in that the void has a flat shape such that the width of the void is more than twice as large as the height of the void , and the height of the void is less than 3mm; and in that the internal void comprises at least one corrugated surface to create turbulent flow within the void , wherein the at least one corrugated surface provides grooves or ribs which are arranged perpendicular to the direction of flow through the void . the void has a flat shape such that the width of the void is more than twice as large as the height of the void , and the height of the void is less than 3mm; and in that the internal void comprises at least one corrugated surface to create turbulent flow within the void , wherein the at least one corrugated surface provides grooves or ribs which are arranged perpendicular to the direction of flow through the void .
A method of drinking from a drinking bottle , the drinking bottle comprising: a container for containing liquid therein; a handle for lifting the container; and a coupling mechanism rotatably coupling the handle to the container; wherein the coupling mechanism is arranged to provide limited rotation of the handle relative to the container between a first position in which the handle extends above the container, and a second position in which the handle is rotated to extend out to the side of the container; and wherein the handle is formed of a resilient material and is arranged to substantially maintain its shape during use so that the container depends from a distal end thereof; the method comprising: gripping the handle of the drinking bottle and lifting the drinking bottle thereby; rotating the handle relative to the container of the drinking bottle from a first position to a second position; tipping the container using the handle in the second position; and drinking from the container. gripping the handle of the drinking bottle and lifting the drinking bottle thereby; rotating the handle relative to the container of the drinking bottle from a first position to a second position; tipping the container using the handle in the second position; and drinking from the container.