mhurhangee/patent-ind-claim-en huggingface dataset:
A non-therapeutic method of induction of superovulation in a cow, comprising the administration of a modified glycoprotein hormone comprising an alpha subunit polypeptide of bovine follicle-stimulating hormone ("FSH") of SEQ ID NO:2, wherein said alpha subunit polypeptide comprises A. an amino acid insert that provides a potential glycosylation site, wherein said insert is placed immediately after position 6 or 7 of said alpha subunit polypeptide; and B. one or more of the following substitutions of a wild-type amino acid of said alpha subunit polypeptide (SEQ ID NO:2) with a basic amino acid: (i) the wild-type amino acid at position 15 is substituted with arginine (R), (ii) the wild-type amino acid at position 17 is substituted with arginine (R), (iii) the wild-type amino acid at position 18 is substituted with arginine (R), lysine (K) or histidine (H), (iv) wild-type amino acid at position 20 is substituted with arginine (R), (v) the wild-type amino acid at position 24 is substituted with arginine (R), and wherein a single dose or two split doses of the modified glycoprotein hormone is/are administered. A. an amino acid insert that provides a potential glycosylation site, wherein said insert is placed immediately after position 6 or 7 of said alpha subunit polypeptide; and B. one or more of the following substitutions of a wild-type amino acid of said alpha subunit polypeptide (SEQ ID NO:2) with a basic amino acid: (i) the wild-type amino acid at position 15 is substituted with arginine (R), (ii) the wild-type amino acid at position 17 is substituted with arginine (R), (iii) the wild-type amino acid at position 18 is substituted with arginine (R), lysine (K) or histidine (H), (iv) wild-type amino acid at position 20 is substituted with arginine (R), (v) the wild-type amino acid at position 24 is substituted with arginine (R), and (i) the wild-type amino acid at position 15 is substituted with arginine (R), (ii) the wild-type amino acid at position 17 is substituted with arginine (R), (iii) the wild-type amino acid at position 18 is substituted with arginine (R), lysine (K) or histidine (H), (iv) wild-type amino acid at position 20 is substituted with arginine (R), (v) the wild-type amino acid at position 24 is substituted with arginine (R), and
One-component thermosetting epoxy resin composition comprising at least one solid epoxy resin EP; at least one latent curing agent for epoxy resins; at least one blowing agent; 0.25% to 4.5% by weight of aerogel particles, based on the total weight of the one-component thermosetting epoxy resin composition, wherein the one-component thermosetting epoxy resin composition has a melt flow index (MFI) of 10-80 g/10 min, especially 20-80 g/10 min, preferably 30-50 g/10 min, the MFI being determined at 110°C and 2.16 kg in accordance with ASTM D1238. at least one solid epoxy resin EP; at least one latent curing agent for epoxy resins; at least one blowing agent; 0.25% to 4.5% by weight of aerogel particles, based on the total weight of the one-component thermosetting epoxy resin composition,
A conversion kit for converting a firearm for firing live rounds to fire only non-lethal training ammunition which comprises a barrel assembly and a slide assembly which replaces the host weapon slide assembly, wherein the barrel assembly includes a barrel which interfaces with the slide assembly , and a projection , the barrel having a chamber for receiving training ammunition only, whereas live rounds will project from the rear of the barrel and hold the slide assembly rearwards a distance from the barrel , and the slide assembly includes a gate which interacts with the projection , the gate comprising a member which has a first end and a second end , wherein the first end interacts in direct manner with the projection and the second end interacts with a biasing means , wherein the member is movable between a first 'safe' position wherein a firing pin of the firearm is blocked from impacting on a cartridge in the chamber and the member is movable to a second 'fire' position wherein the firing pin is not blocked from impacting upon a cartridge in the chamber .
An automatic analyzer for analyzing samples, comprising an immersion tube configured to retrieve a reagent stored in a reagent vessel , a lifting device configured to lift and to lower the immersion tube , wherein the lifting device comprises - a guide rail on which the immersion tube is slidably moveable between a lowered position, in which the immersion tube is configured to be immersed into the reagent vessel , and a lifted position, in which the immersion tube is configured to be retracted from the reagent vessel , and - at least one biasing member configured to bias the immersion tube towards the lowered position with a predetermined biasing force, a detector configured to detect an identity of the reagent, and a locking device configured to lock the immersion tube in the lifted position and to allow the immersion tube to be moved towards the lowered position only if the identity of the reagent detected by the detector corresponds to a target identity of the reagent. a lifting device configured to lift and to lower the immersion tube , wherein the lifting device comprises - a guide rail on which the immersion tube is slidably moveable between a lowered position, in which the immersion tube is configured to be immersed into the reagent vessel , and a lifted position, in which the immersion tube is configured to be retracted from the reagent vessel , and - at least one biasing member configured to bias the immersion tube towards the lowered position with a predetermined biasing force, - a guide rail on which the immersion tube is slidably moveable between a lowered position, in which the immersion tube is configured to be immersed into the reagent vessel , and a lifted position, in which the immersion tube is configured to be retracted from the reagent vessel , and - at least one biasing member configured to bias the immersion tube towards the lowered position with a predetermined biasing force, a detector configured to detect an identity of the reagent, and a locking device configured to lock the immersion tube in the lifted position and to allow the immersion tube to be moved towards the lowered position only if the identity of the reagent detected by the detector corresponds to a target identity of the reagent.
A lateral flow device comprising: a wicking pad composed of a porous material, the wicking pad having a region for applying a substrate comprising immobilized analytes; and wherein the wicking pad has a first end , a second end and two lateral edges ; a first reservoir comprising a stack of a plurality of reagent layers located on the first end of the wicking pad ; and a second reservoir comprising an absorbent pad located on the second end of the wicking pad . a wicking pad composed of a porous material, the wicking pad having a region for applying a substrate comprising immobilized analytes; and wherein the wicking pad has a first end , a second end and two lateral edges ; a first reservoir comprising a stack of a plurality of reagent layers located on the first end of the wicking pad ; and a second reservoir comprising an absorbent pad located on the second end of the wicking pad .
A liquid tank configured to be fixed to or hauled by a vehicle, the liquid tank comprising an internal network of cells formed from layers of cells, each of the cells of the network of cells comprises liquid flow control means (27; 38; 54; 58) in a wall (16; 16A, 16B, 16C; 50; 56) thereof to allow for the minor flow of liquid laterally from cell to cell such that in use, movement of liquid between laterally adjacent cells of the network of cells is retarded such that under conditions of liquid movement within the tank , kinetic energy transferred from the liquid to the lateral tank wall is reduced as compared with the case where no cells are present wherein three or more layers of cells are formed by two or more horizontal dividers, characterised by each of the two or more horizontal dividers comprising a series of relatively small apertures arranged such that each cell has a relatively small aperture , and each of the two or more horizontal dividers comprising a relatively large central aperture , the relatively small apertures having a sufficiently small diameter so as to substantially inhibit the upward movement of liquid in the tank during cornering but allowing the liquid to filter upwardly during tank filling, and the relatively large aperture having a sufficiently large diameter to allow for rapid entry of liquid during tank filling.
A contact device comprising: a contacts mechanism unit including a sealed receptacle and a drive unit , said sealed receptacle configured to house a fixed contact and a movable contact , and said drive unit being configured to move said movable contact between an on position where said movable contact is kept in contact with said fixed contact and an off position where said movable contact is kept away from said fixed contact ; an extinguishing unit including a pair of permanent magnets and a yoke configured to hold said pair of said permanent magnets , said permanent magnets in said pair being arranged on opposite sided of said sealed receptacle with respect to a direction crossing a direction along which said movable contact moves toward and away from said fixed contact ; and, a housing including a base on which said contacts mechanism unit is mounted, and a cover configured to attached to said base such that said contacts mechanism unit and said extinguishing unit are housed between said base and said cover , characterized in that any one of said yoke and said base is provided with an attachment protrusion with the other being provided with an attachment recess configured to receive said attachment protrusion. a contacts mechanism unit including a sealed receptacle and a drive unit , said sealed receptacle configured to house a fixed contact and a movable contact , and said drive unit being configured to move said movable contact between an on position where said movable contact is kept in contact with said fixed contact and an off position where said movable contact is kept away from said fixed contact ; an extinguishing unit including a pair of permanent magnets and a yoke configured to hold said pair of said permanent magnets , said permanent magnets in said pair being arranged on opposite sided of said sealed receptacle with respect to a direction crossing a direction along which said movable contact moves toward and away from said fixed contact ; and, a housing including a base on which said contacts mechanism unit is mounted, and a cover configured to attached to said base such that said contacts mechanism unit and said extinguishing unit are housed between said base and said cover , characterized in that any one of said yoke and said base is provided with an attachment protrusion with the other being provided with an attachment recess configured to receive said attachment protrusion.
Carriage body for a rail vehicle, comprising: - a carriage body housing and - a connecting device , which is arranged in the longitudinal direction in or on the carriage body housing and which is configured to connect the carriage body to two adjacent carriage bodies, wherein the connecting device comprises: - a coupling rod, - a first outer joint for connection to an adjacent carriage body, and - a second outer joint for connection to an adjacent carriage body, wherein the coupling rod can be loaded both in tension and in compression and transmits longitudinal forces directly between the adjacent carriage bodies without loading the carriage body housing in the longitudinal direction, characterized in that the coupling rod comprises: - a central rod , - a first articulated arm , which is connected to the central rod via a first connection , wherein the first articulated arm has the first outer joint on an end facing away from the central rod , and - a second articulated arm , which is connected to the central rod via a second connection , wherein the second articulated arm has the second outer joint on an end facing away from the central rod . - a carriage body housing and - a connecting device , which is arranged in the longitudinal direction in or on the carriage body housing and which is configured to connect the carriage body to two adjacent carriage bodies, wherein the connecting device comprises: - a coupling rod, - a first outer joint for connection to an adjacent carriage body, and - a second outer joint for connection to an adjacent carriage body, - a coupling rod, - a first outer joint for connection to an adjacent carriage body, and - a second outer joint for connection to an adjacent carriage body, wherein the coupling rod can be loaded both in tension and in compression and transmits longitudinal forces directly between the adjacent carriage bodies without loading the carriage body housing in the longitudinal direction, characterized in that the coupling rod comprises: - a central rod , - a first articulated arm , which is connected to the central rod via a first connection , wherein the first articulated arm has the first outer joint on an end facing away from the central rod , and - a second articulated arm , which is connected to the central rod via a second connection , wherein the second articulated arm has the second outer joint on an end facing away from the central rod . - a central rod , - a first articulated arm , which is connected to the central rod via a first connection , wherein the first articulated arm has the first outer joint on an end facing away from the central rod , and - a second articulated arm , which is connected to the central rod via a second connection , wherein the second articulated arm has the second outer joint on an end facing away from the central rod .
A medical device, comprising: a fluid cartridge comprising a chamber and a piston , wherein a volume of the chamber is determined by a position of the piston ; an impeller located within the volume of the chamber ; a static mixer in fluid communication with the volume of the chamber , the static mixer including a tip configured for insertion into a body of a patient; and a first actuator configured to move at least one of the impeller and the piston ; and a lockout mechanism reversibly coupled to the fluid cartridge , wherein (a) the lockout mechanism is movable between a first configuration which prevents the movement of the piston and a second configuration which permits the movement of the piston and (b) the lockout mechanism is characterized in that it moves from the first configuration to the second configuration after the impeller has undergone a predetermined number of rotations within the chamber . a fluid cartridge comprising a chamber and a piston , wherein a volume of the chamber is determined by a position of the piston ; an impeller located within the volume of the chamber ; a static mixer in fluid communication with the volume of the chamber , the static mixer including a tip configured for insertion into a body of a patient; and a first actuator configured to move at least one of the impeller and the piston ; and a lockout mechanism reversibly coupled to the fluid cartridge , wherein (a) the lockout mechanism is movable between a first configuration which prevents the movement of the piston and a second configuration which permits the movement of the piston and (b) the lockout mechanism is characterized in that it moves from the first configuration to the second configuration after the impeller has undergone a predetermined number of rotations within the chamber .
A breathing apparatus having an inspiratory valve , an expiratory valve , and a control unit that is adapted to determine a change in transpulmonary pressure (ΔPtp) in a patient when connected to said breathing apparatus, wherein said control unit is operable to a) set said breathing apparatus in a first mode of operation for ventilating said patient with a first Positive End Expiratory Pressure (PEEP) level by controlling said inspiratory valve and expiratory valve ; b) set said breathing apparatus in a second mode of operation for ventilating said patient with a second PEEP level starting from said first PEEP level, wherein said second PEEP level is based on a target PEEP level different from said first PEEP level, by controlling said inspiratory valve and expiratory valve ; characterized in that the control unit is further operable to c) determine a change in end-expiratory lung volume (ΔEELV) from a difference of end-expiratory lung volume (EELV) present at said first PEEP level and said second PEEP level; and determine said change in transpulmonary pressure (ΔPtp) based on said change in end-expiratory lung volume (ΔEELV) and a difference between said first PEEP level and said second PEEP level (ΔPEEP), and wherein said first and/or second mode of operation comprise at least one breathing cycle. a) set said breathing apparatus in a first mode of operation for ventilating said patient with a first Positive End Expiratory Pressure (PEEP) level by controlling said inspiratory valve and expiratory valve ; b) set said breathing apparatus in a second mode of operation for ventilating said patient with a second PEEP level starting from said first PEEP level, wherein said second PEEP level is based on a target PEEP level different from said first PEEP level, by controlling said inspiratory valve and expiratory valve ; characterized in that the control unit is further operable to c) determine a change in end-expiratory lung volume (ΔEELV) from a difference of end-expiratory lung volume (EELV) present at said first PEEP level and said second PEEP level; and determine said change in transpulmonary pressure (ΔPtp) based on said change in end-expiratory lung volume (ΔEELV) and a difference between said first PEEP level and said second PEEP level (ΔPEEP), and wherein said first and/or second mode of operation comprise at least one breathing cycle.
An antibacterial composition, comprising: water; alcohol, wherein the alcohol is present in an amount of 60 to 80% by weight of the overall antibacterial composition; a thickening agent; and a moisturizing oil, wherein at least 50% of droplets of the moisturizing oil present in the antibacterial composition have a D particle size of 50 micrometers to 2.5 millimeters. water; alcohol, wherein the alcohol is present in an amount of 60 to 80% by weight of the overall antibacterial composition; a thickening agent; and a moisturizing oil, wherein at least 50% of droplets of the moisturizing oil present in the antibacterial composition have a D particle size of 50 micrometers to 2.5 millimeters.
Control system a motor vehicle powertrain with a human driver with anti-skid function, the system comprising a first control module configured to generate a first engine torque setpoint for traction and speed. stability of the vehicle in reaction to a detection of a slip state of at least one wheel with respect to the ground , a second control module for defining a so-called coordinate torque command by limiting, if the first torque setpoint is generated by the first control module 100), a torque command defined by the human driver to at most the first torque setpoint , and a data transfer system (B) for transmitting setpoints from the first control module to a computer of the system control implementing the second control module , characterized in that the first module is further configured to generate a speed limitation setpoint for the powertrain according to a current vehicle speed and the system further includes a third control module implemented by said computer and configured to generate an advanced torque setpoint for propulsion of the vehicle based on the coordinated torque command which it limits as a function of the current speed of the powertrain (R) and said speed limitation instruction .
A cable tie having a desired length of flexible belt and a buckle connected to one longitudinal end of the belt , and configured to clamp a clamped article (W) by inserting the other longitudinal end of the belt into a through hole of the buckle and tightening the belt in loop shape, the cable tie comprising: rack teeth that are formed in one surface of the belt and are arranged in a longitudinal direction of the belt , an engagement strip that is positioned in the through hole of the buckle and is configured to be deformed about its proximal end connected to an inner wall of the buckle , and an engagement claw that is formed in the engagement strip in order to engage the rack teeth of the belt inserted into the through hole of the buckle , wherein the engagement claw has an engagement surface that faces in an insertion direction of the belt and that faces a tooth surface of one of the rack teeth in a condition in which the engagement claw engages one of the rack teeth upon insertion of the belt into the through hole of the buckle , characterized in that the engagement claw has a height greater than a height of each of the rack teeth , so that the engagement strip is configured to be deformed due to contact of the engagement claw with a bottom surface of one of tooth spaces of the rack teeth of the belt inserted into the through hole of the buckle , so that a crossing angle (A) is formed between the engagement surface of the engagement claw and the tooth surface of one of the rack teeth in a fastened condition in which the belt is inserted into the through hole of the buckle and is tightened. rack teeth that are formed in one surface of the belt and are arranged in a longitudinal direction of the belt , an engagement strip that is positioned in the through hole of the buckle and is configured to be deformed about its proximal end connected to an inner wall of the buckle , and an engagement claw that is formed in the engagement strip in order to engage the rack teeth of the belt inserted into the through hole of the buckle , wherein the engagement claw has an engagement surface that faces in an insertion direction of the belt and that faces a tooth surface of one of the rack teeth in a condition in which the engagement claw engages one of the rack teeth upon insertion of the belt into the through hole of the buckle , characterized in that the engagement claw has a height greater than a height of each of the rack teeth , so that the engagement strip is configured to be deformed due to contact of the engagement claw with a bottom surface of one of tooth spaces of the rack teeth of the belt inserted into the through hole of the buckle , so that a crossing angle (A) is formed between the engagement surface of the engagement claw and the tooth surface of one of the rack teeth in a fastened condition in which the belt is inserted into the through hole of the buckle and is tightened.