mhurhangee/patent-ind-claim-en huggingface dataset:
CAIX binding polypeptide, comprising a CAIX binding motif BM, which motif consists of an amino acid sequence selected from: i) EX 2 X 3 X 4 AX 6 X 7 EIX 10 X 11 LPNLX 16 X 17 X 18 QX 20 X 21 AFIYX 26 LWD whe rein, independently from each other, X 2 is selected from D, H, N, Q and W; X 3 is selected from I, L, Q, R, S and W; X 4 is selected from A, F, N, W and Y; X 6 is selected from A, G, S and W; X 7 is selected from G, I, V and W; X 10 is selected from A, D, E, G, H, N, Q, R, S and T; X 11 is selected from D, E and S; X 16 is selected from N and T; X 17 is selected from A, D, E, G, I, Q, S, T, V and W; X 18 is selected from A, D, E, F, G, H, I, N, Q, R, T and Y; X 20 is selected from Q and R; X 21 is selected from D, H, N and Q; X 26 is selected from K and S; and ii) an amino acid sequence which has at least 97 % identity to the sequence defined in i), the polypeptide being capable of binding to CAIX such that the K D value of the interaction is at most 1 x 10 -6 M as measured using surface plasmon resonance. i) EX 2 X 3 X 4 AX 6 X 7 EIX 10 X 11 LPNLX 16 X 17 X 18 QX 20 X 21 AFIYX 26 LWD whe rein, independently from each other, X 2 is selected from D, H, N, Q and W; X 3 is selected from I, L, Q, R, S and W; X 4 is selected from A, F, N, W and Y; X 6 is selected from A, G, S and W; X 7 is selected from G, I, V and W; X 10 is selected from A, D, E, G, H, N, Q, R, S and T; X 11 is selected from D, E and S; X 16 is selected from N and T; X 17 is selected from A, D, E, G, I, Q, S, T, V and W; X 18 is selected from A, D, E, F, G, H, I, N, Q, R, T and Y; X 20 is selected from Q and R; X 21 is selected from D, H, N and Q; X 26 is selected from K and S; and X 2 is selected from D, H, N, Q and W; X 3 is selected from I, L, Q, R, S and W; X 4 is selected from A, F, N, W and Y; X 6 is selected from A, G, S and W; X 7 is selected from G, I, V and W; X 10 is selected from A, D, E, G, H, N, Q, R, S and T; X 11 is selected from D, E and S; X 16 is selected from N and T; X 17 is selected from A, D, E, G, I, Q, S, T, V and W; X 18 is selected from A, D, E, F, G, H, I, N, Q, R, T and Y; X 20 is selected from Q and R; X 21 is selected from D, H, N and Q; X 26 is selected from K and S; ii) an amino acid sequence which has at least 97 % identity to the sequence defined in i),
A multirotor wind turbine comprising: - a tower formed by a tower wall extending between a tower bottom and a tower top, - a yaw arrangement carried by the tower and comprising an outer wall being rotationally suspended about the tower , - at least two energy generating units , each carried by an arm extending from the outer wall , and - a load management system for hoisting articles from the tower bottom to each energy generating unit via the yaw arrangement , wherein a yaw space is formed between the tower wall and the outer wall , the yaw space being accessible for the load management system for hoisting the articles from the tower bottom to each energy generating unit through the yaw space, and wherein the yaw space is a closed space which can only be entered from the tower or from the arms . - a tower formed by a tower wall extending between a tower bottom and a tower top, - a yaw arrangement carried by the tower and comprising an outer wall being rotationally suspended about the tower , - at least two energy generating units , each carried by an arm extending from the outer wall , and - a load management system for hoisting articles from the tower bottom to each energy generating unit via the yaw arrangement ,
A production method of a rubber composition based on an elastomer matrix, a reinforcing filler, and reinforcing fibers selected from the group consisting of basalt fibers, glass fibers, carbon fibers and the mixtures thereof, comprising at least a step of incorporating at least the reinforcing fibers into the rubber composition in a mixer provided with at least two rolls having a roll nip which is equal to or above the volume average length of reinforcing fibers before incorporating the reinforcing fibers into the rubber composition, wherein the volume average length of reinforcing fibers before incorporating the reinforcing fibers into the rubber composition is at least 1.0 mm.
Supply unit configured to supply a specific type of coffee beans, said supply unit being provided with at least a containing device in which the coffee beans of the specific type of coffee are contained, with a first volumetric feed device configured to feed a volumetrically metered quantity of coffee beans of a specific type of coffee beans from said containing device , and with a second singularized feed device configured to remove coffee beans, one at a time, in a singularized manner, from said containing device , said supply unit being characterized in that said containing device comprises a containing compartment of said type of coffee beans, and in that said second singularized feed device is installed in said compartment .
An implant sized and adapted for insertion into an intervertebral space between adjacent vertebral bodies comprising: a non-resorbable, structural framework having top and bottom bone-contacting surfaces and a plurality of struts defining geometric openings between the top and bottom bone-contacting surfaces, the struts providing structural support for the framework ; and a resorbable material component embedded within and/or around the framework for resorption and formation of new bone to fuse the vertebral bodies together; characterized in that the resorbable material component is embedded within the struts and has top and bottom bone-contacting surfaces, the top and bottom bone-contacting surfaces of the resorbable material component being arranged to contact the vertebral endplates over a contact surface area such that the resorbable material component acts to distribute some contact loads between the implant and the vertebral bodies across an extent of the implant to reduce peak stresses between the framework and the vertebral bodies, thereby reducing or eliminating subsidence of the framework into the vertebral bodies; and in that the implant further comprises a bone anchor having a bladed portion and a keyed interconnection portion , and the framework includes at least one keyed opening sized and shaped to receive the keyed interconnection portion . a non-resorbable, structural framework having top and bottom bone-contacting surfaces and a plurality of struts defining geometric openings between the top and bottom bone-contacting surfaces, the struts providing structural support for the framework ; and a resorbable material component embedded within and/or around the framework for resorption and formation of new bone to fuse the vertebral bodies together; characterized in that the resorbable material component is embedded within the struts and has top and bottom bone-contacting surfaces, the top and bottom bone-contacting surfaces of the resorbable material component being arranged to contact the vertebral endplates over a contact surface area such that the resorbable material component acts to distribute some contact loads between the implant and the vertebral bodies across an extent of the implant to reduce peak stresses between the framework and the vertebral bodies, thereby reducing or eliminating subsidence of the framework into the vertebral bodies; and in that the implant further comprises a bone anchor having a bladed portion and a keyed interconnection portion , and the framework includes at least one keyed opening sized and shaped to receive the keyed interconnection portion .
An intraoral orthosis comprising - an upper splint and a lower splint designed to line teeth of an upper jaw and teeth of a lower jaw, respectively, - two tie rods connecting the splints , these tie rods having such a length that the lower jaw is maintained in an advanced position relative to the upper jaw, characterized in that the tie rods have fixed points of attachment to the splints - on the one hand, to the upper splint at the canines, and, - on the other hand, to the lower splint at the second mandibular molar, wherein the lower splint comprises means for fixation of the tie rods permitting to shift the point of attachment of the tie rods in the occlusal plane of contact of the lower and upper teeth. - an upper splint and a lower splint designed to line teeth of an upper jaw and teeth of a lower jaw, respectively, - two tie rods connecting the splints , these tie rods having such a length that the lower jaw is maintained in an advanced position relative to the upper jaw, characterized in that the tie rods have fixed points of attachment to the splints - on the one hand, to the upper splint at the canines, and, - on the other hand, to the lower splint at the second mandibular molar, wherein the lower splint comprises means for fixation of the tie rods permitting to shift the point of attachment of the tie rods in the occlusal plane of contact of the lower and upper teeth.
A sheet feeding apparatus comprising: at least one conveying belt that conveys an uppermost or lowermost sheet of a sheet stack placed on a conveying surface in a feed out direction and in which a plurality of airflow holes are formed; a suction unit that is arranged on a back surface side, which is the opposite side of the conveying surface of the conveying belt , and in which a first intake hole that sucks the sheet via the airflow holes is formed; at least one lifting plate that reciprocates between a first position located in a sheet accumulation direction with respect to the conveying surface and a second position located at the same height position as the conveying surface or on the back surface side with respect to the conveying surface; and a control unit that controls movement of the lifting plate , characterized in that the control unit is configured to move the lifting plate from the second position to the first position when the uppermost or lowermost sheet is being conveyed, the lifting plate being configured to open a second intake hole, which is different from the first intake hole, formed in the suction unit when the lifting plate is at the first position, and to close the second intake hole when the lifting plate is at the second position. at least one conveying belt that conveys an uppermost or lowermost sheet of a sheet stack placed on a conveying surface in a feed out direction and in which a plurality of airflow holes are formed; a suction unit that is arranged on a back surface side, which is the opposite side of the conveying surface of the conveying belt , and in which a first intake hole that sucks the sheet via the airflow holes is formed; at least one lifting plate that reciprocates between a first position located in a sheet accumulation direction with respect to the conveying surface and a second position located at the same height position as the conveying surface or on the back surface side with respect to the conveying surface; and a control unit that controls movement of the lifting plate , characterized in that the control unit is configured to move the lifting plate from the second position to the first position when the uppermost or lowermost sheet is being conveyed, the lifting plate being configured to open a second intake hole, which is different from the first intake hole, formed in the suction unit when the lifting plate is at the first position, and to close the second intake hole when the lifting plate is at the second position.
A method for removing a substance comprising oxygen from a feedstock comprising a solid metal or metal compound, comprising the steps of: providing a fused-salt melt comprising a fused salt, a reactive-metal oxide and a reactive metal, the fused salt comprising a halide anion species, the reactive metal comprising Ca, Li, Na or Mg, and the reactive metal being capable of reaction to remove at least a portion of the substance from the feedstock; contacting the melt with a cathode; contacting the cathode and the melt with the feedstock; contacting the melt with an anode; and applying a current between the cathode and the anode such that at least a portion of the substance is removed from the feedstock; in which a quantity of the reactive metal in the melt is sufficient to prevent the Damkohler number, Da, as defined in the description of the application as filed between page 9, line 26, and page 11, line 16, from exceeding 1 at any time. providing a fused-salt melt comprising a fused salt, a reactive-metal oxide and a reactive metal, the fused salt comprising a halide anion species, the reactive metal comprising Ca, Li, Na or Mg, and the reactive metal being capable of reaction to remove at least a portion of the substance from the feedstock; contacting the melt with a cathode; contacting the cathode and the melt with the feedstock; contacting the melt with an anode; and applying a current between the cathode and the anode such that at least a portion of the substance is removed from the feedstock; in which a quantity of the reactive metal in the melt is sufficient to prevent the Damkohler number, Da, as defined in the description of the application as filed between page 9, line 26, and page 11, line 16, from exceeding 1 at any time.
A smokeless flavor inhalator comprising: a carbon heat source ; a tobacco material located downstream of the heat source ; and a heat source holder attached to at least a part of the heat source , the carbon heat source being attached to a distal end of the heat source holder , the heat source holder having heat resistance and being tubular in shape, a peripheral wall of the heat source holder having a laminated structure and including a metal layer which constitutes an inner surface of the peripheral wall, and a cooling element , characterized in that the peripheral wall of the heat source holder includes a paper layer which is superposed on the metal layer, and an incombustible material which is superposed on the paper layer, and the cooling element is coupled to downstream of the heat source ; wherein the cooling element includes internal passages. a carbon heat source ; a tobacco material located downstream of the heat source ; and a heat source holder attached to at least a part of the heat source , the carbon heat source being attached to a distal end of the heat source holder , the heat source holder having heat resistance and being tubular in shape, a peripheral wall of the heat source holder having a laminated structure and including a metal layer which constitutes an inner surface of the peripheral wall, and a cooling element , characterized in that the peripheral wall of the heat source holder includes a paper layer which is superposed on the metal layer, and an incombustible material which is superposed on the paper layer, and the cooling element is coupled to downstream of the heat source ; wherein the cooling element includes internal passages.
A pole support system comprising: a tubular lower support ; a guide member interior to the lower support , the guide member extending along a length of the lower support , such that an annular space is formed between the tubular lower support and the guide member ; a base coupled with the guide member and the lower support , the base being coupled to the guide member such that an interior of the guide member is isolated from the annular space ; a telescoping upper support inside the lower support and axially movable between an extended position and a retracted position, the upper support being at least partially received in the annular space between the lower support and the guide member ; a biasing member biasing the telescoping upper support to the extended position; and a locking assembly partially surrounding the lower support at the end of the lower support opposite the base , the locking assembly comprising: a body having a passage in which the telescoping upper support slides therethrough, the body attached to the lower support to enclose the passage at a first end while maintaining the passage in fluid communication with the interior of the lower support ; and a lock configured to selectably engage the telescoping upper support to constrain axial motion of the upper support . a tubular lower support ; a guide member interior to the lower support , the guide member extending along a length of the lower support , such that an annular space is formed between the tubular lower support and the guide member ; a base coupled with the guide member and the lower support , the base being coupled to the guide member such that an interior of the guide member is isolated from the annular space ; a telescoping upper support inside the lower support and axially movable between an extended position and a retracted position, the upper support being at least partially received in the annular space between the lower support and the guide member ; a biasing member biasing the telescoping upper support to the extended position; and a locking assembly partially surrounding the lower support at the end of the lower support opposite the base , the locking assembly comprising: a body having a passage in which the telescoping upper support slides therethrough, the body attached to the lower support to enclose the passage at a first end while maintaining the passage in fluid communication with the interior of the lower support ; and a lock configured to selectably engage the telescoping upper support to constrain axial motion of the upper support . a body having a passage in which the telescoping upper support slides therethrough, the body attached to the lower support to enclose the passage at a first end while maintaining the passage in fluid communication with the interior of the lower support ; and a lock configured to selectably engage the telescoping upper support to constrain axial motion of the upper support .
A system comprising: twelve magnetic field detectors for spatial distribution across a dimension of a target containing both a hydrocarbon and a mixture comprised of water and hydrophilic magnetic nanoparticles , the twelve magnetic field detectors being configured to detect a magnetic field associated with the hydrophilic magnetic nanoparticles ; wherein the twelve magnetic field detectors are arranged circumferentially around a core in three arrays of four magnetic field detectors ; wherein each of the twelve magnetic field detectors is offset 90 degrees from its circumferential neighbor; and wherein the hydrophilic magnetic nanoparticles are immiscible in crude oil; the hydrophilic magnetic nanoparticles ; a core holder , wherein the twelve magnetic field detectors are on the core holder ; a means for forcing the mixture comprised of the water and the hydrophilic magnetic nanoparticles through the target; and a data processing system to determine a saturation profile of the target based on the magnetic field, wherein the target is the core of a reservoir formation comprised of porous rock, the core being held by the core holder . twelve magnetic field detectors for spatial distribution across a dimension of a target containing both a hydrocarbon and a mixture comprised of water and hydrophilic magnetic nanoparticles , the twelve magnetic field detectors being configured to detect a magnetic field associated with the hydrophilic magnetic nanoparticles ; wherein the twelve magnetic field detectors are arranged circumferentially around a core in three arrays of four magnetic field detectors ; wherein each of the twelve magnetic field detectors is offset 90 degrees from its circumferential neighbor; and wherein the hydrophilic magnetic nanoparticles are immiscible in crude oil; the hydrophilic magnetic nanoparticles ; a core holder , wherein the twelve magnetic field detectors are on the core holder ; a means for forcing the mixture comprised of the water and the hydrophilic magnetic nanoparticles through the target; and a data processing system to determine a saturation profile of the target based on the magnetic field, wherein the target is the core of a reservoir formation comprised of porous rock, the core being held by the core holder .
A variable area turbine arrangement (100;200), comprising: a first turbine section having at least a first variable vane row ; a second turbine section downstream from said first turbine section and having at least a second variable vane row ; and a transition duct disposed between said first turbine section and said second turbine section , the transition duct including a radially outer wall and a radially inner wall , each of the radially outer wall and radially inner wall including sloped portions sloped in the radially outboard direction and positioned between an outlet of the first turbine section and an inlet of the second turbine section , wherein the outlet and the inlet are both substantially parallel to the engine centerline longitudinal axis (A), characterised by at least one stationary vane positioned within said transition duct . a first turbine section having at least a first variable vane row ; a second turbine section downstream from said first turbine section and having at least a second variable vane row ; and a transition duct disposed between said first turbine section and said second turbine section , the transition duct including a radially outer wall and a radially inner wall , each of the radially outer wall and radially inner wall including sloped portions sloped in the radially outboard direction and positioned between an outlet of the first turbine section and an inlet of the second turbine section , wherein the outlet and the inlet are both substantially parallel to the engine centerline longitudinal axis (A), characterised by at least one stationary vane positioned within said transition duct .
A system for treating a patient, the system comprising: a cerebrospinal fluid, CSF, shunt configured for deployment through a venous system of the patient, the shunt comprising a proximal portion , a distal portion having a distal anchoring mechanism , and a shunt lumen in fluid communication with one or more distal openings in the distal portion and one or more proximal openings in the proximal portion ; and a delivery system configured for creating an anastomosis between an inferior petrosal sinus and a CSF-filled subarachnoid space of the patient, and for deploying the shunt in the anastomosis with the distal portion of the shunt positioned in the subarachnoid space , such that, when the shunt is deployed in the anastomosis , CSF flows from the subarachnoid space through the one or more distal openings , lumen , and one or more proximal openings of the shunt , respectively, into the venous system of the patient, the delivery system further comprising a delivery catheter having a tissue penetrating distal tip , a delivery catheter lumen , and an open distal end in communication with the delivery catheter lumen , wherein the delivery catheter lumen is configured to carry the shunt through a passage of the venous system of the patient for deployment in the anastomosis . a cerebrospinal fluid, CSF, shunt configured for deployment through a venous system of the patient, the shunt comprising a proximal portion , a distal portion having a distal anchoring mechanism , and a shunt lumen in fluid communication with one or more distal openings in the distal portion and one or more proximal openings in the proximal portion ; and a delivery system configured for creating an anastomosis between an inferior petrosal sinus and a CSF-filled subarachnoid space of the patient, and for deploying the shunt in the anastomosis with the distal portion of the shunt positioned in the subarachnoid space , such that, when the shunt is deployed in the anastomosis , CSF flows from the subarachnoid space through the one or more distal openings , lumen , and one or more proximal openings of the shunt , respectively, into the venous system of the patient, the delivery system further comprising a delivery catheter having a tissue penetrating distal tip , a delivery catheter lumen , and an open distal end in communication with the delivery catheter lumen , wherein the delivery catheter lumen is configured to carry the shunt through a passage of the venous system of the patient for deployment in the anastomosis .