A system for providing electroporation, the system comprising: a first electrode and a second electrode configured to be placed in a renal area of a patient ; a sensor; and a pulse generator coupled to the first electrode, the second electrode, and the sensor, the pulse generator comprising: a memory that is capable of storing computer executable instructions; and a processor that is configured to facilitate execution of the executable instructions stored in the memory, wherein the instructions cause the processor to: generate, via the pulse generator, a stimulation electrical current to cause stimulation between the first electrode and the second electrode for the renal area ; detect , via the sensor, a change in blood pressure of the patient resulting from the stimulation electrical current; and in response to detecting the change in blood pressure of the patient , generate an electroporation electrical current to cause reversible or irreversible electroporation between the first electrode and the second electrode for the renal area . a first electrode and a second electrode configured to be placed in a renal area of a patient ; a sensor; and a pulse generator coupled to the first electrode, the second electrode, and the sensor, the pulse generator comprising: a memory that is capable of storing computer executable instructions; and a processor that is configured to facilitate execution of the executable instructions stored in the memory, wherein the instructions cause the processor to: generate, via the pulse generator, a stimulation electrical current to cause stimulation between the first electrode and the second electrode for the renal area ; detect , via the sensor, a change in blood pressure of the patient resulting from the stimulation electrical current; and in response to detecting the change in blood pressure of the patient , generate an electroporation electrical current to cause reversible or irreversible electroporation between the first electrode and the second electrode for the renal area . a memory that is capable of storing computer executable instructions; and a processor that is configured to facilitate execution of the executable instructions stored in the memory, wherein the instructions cause the processor to: generate, via the pulse generator, a stimulation electrical current to cause stimulation between the first electrode and the second electrode for the renal area ; detect , via the sensor, a change in blood pressure of the patient resulting from the stimulation electrical current; and in response to detecting the change in blood pressure of the patient , generate an electroporation electrical current to cause reversible or irreversible electroporation between the first electrode and the second electrode for the renal area . generate, via the pulse generator, a stimulation electrical current to cause stimulation between the first electrode and the second electrode for the renal area ; detect , via the sensor, a change in blood pressure of the patient resulting from the stimulation electrical current; and in response to detecting the change in blood pressure of the patient , generate an electroporation electrical current to cause reversible or irreversible electroporation between the first electrode and the second electrode for the renal area . <EOS>