mhurhangee/patent-ind-claim-en huggingface dataset:
A method to select conformation-selective binding agents of a protein complex, the method comprising the steps of: a) Displaying a collection of binding agents at the extracellular surface of a population of cells b) Using cell sorting to separate, from said population of cells of a), cells displaying binding agents that i. specifically bind to a protein complex conformation and not to the individual members of the complex, and/or ii. specifically bind to one of the individual members of a protein complex and not to the protein complex conformation nor to the other individual member(s) of the complex, and/or iii. specifically bind to one of the individual members of a protein complex and to a protein complex conformation and not to the other individual member(s) of the complex wherein said protein complex is a protein-protein complex that is constituted of at least two interacting monomeric proteins, or wherein said protein complex is a protein-nucleic acid complex that is constituted of at least one monomeric protein interacting with at least one nucleic acid molecule. a) Displaying a collection of binding agents at the extracellular surface of a population of cells b) Using cell sorting to separate, from said population of cells of a), cells displaying binding agents that i. specifically bind to a protein complex conformation and not to the individual members of the complex, and/or ii. specifically bind to one of the individual members of a protein complex and not to the protein complex conformation nor to the other individual member(s) of the complex, and/or iii. specifically bind to one of the individual members of a protein complex and to a protein complex conformation and not to the other individual member(s) of the complex wherein said protein complex is a protein-protein complex that is constituted of at least two interacting monomeric proteins, or wherein said protein complex is a protein-nucleic acid complex that is constituted of at least one monomeric protein interacting with at least one nucleic acid molecule. i. specifically bind to a protein complex conformation and not to the individual members of the complex, and/or ii. specifically bind to one of the individual members of a protein complex and not to the protein complex conformation nor to the other individual member(s) of the complex, and/or iii. specifically bind to one of the individual members of a protein complex and to a protein complex conformation and not to the other individual member(s) of the complex
Projecting system for a display, especially a head-up display intended for a motor vehicle, said system projecting a virtual image that is visible only in a region called the eyebox, and comprising: - a semi-reflective optical element , - a back-lighting device , - a screen suitable for being backlit by said back-lighting device and suitable for illuminating the semi-reflective optical element via illumination cones , each illumination cone having an axis, called the indicator , that starts at a point , called the apex of the cone, located on the screen and that is directed toward the semi-reflective optical element , said projecting system comprising means for orienting directions of the indicators of the cones , said orienting means being suitable for orienting the indicators in a direction computed via an orientation function dependent on the distance of each cone apex from the centre of the screen , the back-lighting device comprising light sources , said projecting system being characterized in that the orientating means comprise a holder of the light sources that is suitable for orienting the light originating from each light source so that said light, when incident on a point of incidence on the screen , is in the direction of the indicator of the cone the apex of which is said point of incidence, so as to illuminate the eyebox without loss of illuminance. - a semi-reflective optical element , - a back-lighting device , - a screen suitable for being backlit by said back-lighting device and suitable for illuminating the semi-reflective optical element via illumination cones , each illumination cone having an axis, called the indicator , that starts at a point , called the apex of the cone, located on the screen and that is directed toward the semi-reflective optical element , said projecting system comprising means for orienting directions of the indicators of the cones , said orienting means being suitable for orienting the indicators in a direction computed via an orientation function dependent on the distance of each cone apex from the centre of the screen , the back-lighting device comprising light sources , said projecting system being characterized in that the orientating means comprise a holder of the light sources that is suitable for orienting the light originating from each light source so that said light, when incident on a point of incidence on the screen , is in the direction of the indicator of the cone the apex of which is said point of incidence, so as to illuminate the eyebox without loss of illuminance.
A drive system for a traction vehicle, the drive system comprising: a fuel powered motor ; a generator driven by the fuel powered motor , the generator being adapted for generating a multi-phase AC current, when driven by the fuel powered motor ; two generator side inverters supplied by the generator ; two DC links interconnectable with a DC supply network for supplying the traction vehicle with DC power; two drive motor side inverters ; a plurality of drive motors of the vehicle supplied by the drive motor side inverters ; characterised in that each generator side inverter supplies one of the DC links , which is interconnected with one of the drive motor side inverters ; the generator has two galvanically separated stator winding systems . each stator winding system supplying one of the generator side inverters ; the drive system comprises two controllers , each controller being adapted for controlling one of the generator side inverters ; the controllers are adapted for synchronizing each other as a master controller and a slave controller ; the master controller is adapted for evaluating measurement signals from the drive system , determining reference signals for stator voltages for both stator winding systems and for generating switching signals for its corresponding generator side inverter ; the slave controller is adapted for synchronizing with the master controller , receiving reference signals for the stator voltages and for generating switching signals for its corresponding generator side inverter . a fuel powered motor ; a generator driven by the fuel powered motor , the generator being adapted for generating a multi-phase AC current, when driven by the fuel powered motor ; two generator side inverters supplied by the generator ; two DC links interconnectable with a DC supply network for supplying the traction vehicle with DC power; two drive motor side inverters ; a plurality of drive motors of the vehicle supplied by the drive motor side inverters ; characterised in that each generator side inverter supplies one of the DC links , which is interconnected with one of the drive motor side inverters ; the generator has two galvanically separated stator winding systems . each stator winding system supplying one of the generator side inverters ; the drive system comprises two controllers , each controller being adapted for controlling one of the generator side inverters ; the controllers are adapted for synchronizing each other as a master controller and a slave controller ; the master controller is adapted for evaluating measurement signals from the drive system , determining reference signals for stator voltages for both stator winding systems and for generating switching signals for its corresponding generator side inverter ; the slave controller is adapted for synchronizing with the master controller , receiving reference signals for the stator voltages and for generating switching signals for its corresponding generator side inverter .
A process for manufacturing a high strength and high thermal conductivity wrought nickel alloy having a thermal conductivity of nearly 90W/m.K, the process comprising: providing a metal powder consisting of a blend of unalloyed nickel powder and an incoherent particle powder selected from the group consisting of metal oxides, metal nitrides, metal carbides and combinations thereof and having thermo-dynamic stability up to the melting point of nickel wherein the incoherent particles resist coarsening over the thermo-mechanical processing range of nickel, or alternatively providing a metal powder by providing a nickel oxide powder with ultra-fine oxide dispersion, that is proportionally blended with a nickel and aluminium alloy powder, wherein the proportion is determined by a need for the nickel oxide powder to react with the nickel and aluminum alloy powder to form nickel metal and aluminium oxide; as incoherent particles; subsequently, forming a composite powder from the metal powder; removing air and absorbed water from the composite powder; and hot extruding the composite powder to full density, wherein the forming the composite powder comprises ball milling the metal powder under a gaseous atmosphere or under a cryoliquid; and wherein the incoherent particles have a particle radius of about 10 to 20 nanometres, an interparticle spacing of about 100 nm or at least two times the particle size, and the nickel alloy has a volume fraction of 0.05 of the incoherent particles. providing a metal powder consisting of a blend of unalloyed nickel powder and an incoherent particle powder selected from the group consisting of metal oxides, metal nitrides, metal carbides and combinations thereof and having thermo-dynamic stability up to the melting point of nickel wherein the incoherent particles resist coarsening over the thermo-mechanical processing range of nickel, or alternatively providing a metal powder by providing a nickel oxide powder with ultra-fine oxide dispersion, that is proportionally blended with a nickel and aluminium alloy powder, wherein the proportion is determined by a need for the nickel oxide powder to react with the nickel and aluminum alloy powder to form nickel metal and aluminium oxide; as incoherent particles; subsequently, forming a composite powder from the metal powder; removing air and absorbed water from the composite powder; and hot extruding the composite powder to full density, wherein the forming the composite powder comprises ball milling the metal powder under a gaseous atmosphere or under a cryoliquid; and wherein the incoherent particles have a particle radius of about 10 to 20 nanometres, an interparticle spacing of about 100 nm or at least two times the particle size, and the nickel alloy has a volume fraction of 0.05 of the incoherent particles.
A dentifrice comprising: a source of stannous ions; a source of fluoride ions comprising sodium fluoride and amine fluoride; a non-crustacean derived chitosan, or pharmaceutically acceptable acid addition salt thereof; and an abrasive system, wherein said chitosan has a molecular weight of 15 to 40 kDa, and is present in an amount of 0.4 to 1.5 weight percent based on the total composition. a source of stannous ions; a source of fluoride ions comprising sodium fluoride and amine fluoride; a non-crustacean derived chitosan, or pharmaceutically acceptable acid addition salt thereof; and an abrasive system, wherein said chitosan has a molecular weight of 15 to 40 kDa, and is present in an amount of 0.4 to 1.5 weight percent based on the total composition.
Method for processing a carcass part of slaughtered poultry, which carcass part comprises: - bone parts with at least a part of the rib cage and a part of the spine, - at least a part of the back meat that is naturally present on the rib cage and the spine, - at least a part of the abdominal muscle tissue , this method comprising the following steps: - making a first incision through the back meat near the abdominal muscle tissue at least up to the underlying bone parts of the carcass part , between the attachment of the back meat to the rib cage and the location of the neck of the carcass part, thereby severing the back meat to be harvested from the connection of the back meat from the rib cage, so that when the back meat is removed from the bone parts of the carcass part the abdominal muscle tissue remains behind on the bone parts, - detaching the back meat from the bone parts of the carcass part . - bone parts with at least a part of the rib cage and a part of the spine, - at least a part of the back meat that is naturally present on the rib cage and the spine, - at least a part of the abdominal muscle tissue , - making a first incision through the back meat near the abdominal muscle tissue at least up to the underlying bone parts of the carcass part , between the attachment of the back meat to the rib cage and the location of the neck of the carcass part, thereby severing the back meat to be harvested from the connection of the back meat from the rib cage, so that when the back meat is removed from the bone parts of the carcass part the abdominal muscle tissue remains behind on the bone parts, - detaching the back meat from the bone parts of the carcass part .
A base station apparatus used in a cellular communication network, the base station apparatus comprising: at least one wireless transceiver ; and a processor configured to: transmit Vehicle-to-Everything, V2X, support information to a first radio terminal via the at least one wireless transceiver , the V2X support information indicating that a V2X Service is supported by a serving network including the base station apparatus ; and after receiving V2X terminal information transmitted from the first radio terminal that has received the V2X support information, perform resource allocation for the V2X service, characterized in that the V2X support information indicates a list of V2X service areas in which the V2X service is available, and a radio resource pool per V2X service area to be used for autonomous resource selection for the V2X service by each of a plurality of radio terminals including the first radio terminal , wherein the V2X support information indicates a first radio resource pool is associated with a first V2X service area, and wherein the V2X support information indicates a second radio resource pool is associated with a second V2X service area. at least one wireless transceiver ; and a processor configured to: transmit Vehicle-to-Everything, V2X, support information to a first radio terminal via the at least one wireless transceiver , the V2X support information indicating that a V2X Service is supported by a serving network including the base station apparatus ; and after receiving V2X terminal information transmitted from the first radio terminal that has received the V2X support information, perform resource allocation for the V2X service, transmit Vehicle-to-Everything, V2X, support information to a first radio terminal via the at least one wireless transceiver , the V2X support information indicating that a V2X Service is supported by a serving network including the base station apparatus ; and after receiving V2X terminal information transmitted from the first radio terminal that has received the V2X support information, perform resource allocation for the V2X service, characterized in that the V2X support information indicates a list of V2X service areas in which the V2X service is available, and a radio resource pool per V2X service area to be used for autonomous resource selection for the V2X service by each of a plurality of radio terminals including the first radio terminal , wherein the V2X support information indicates a first radio resource pool is associated with a first V2X service area, and wherein the V2X support information indicates a second radio resource pool is associated with a second V2X service area.
A process for preparation of a liquid organomagnesium precursor having formula {Mg(OR')X}.a{MgX 2 }.b{Mg(OR') 2 }.c{R'OH}, wherein R' is selected from a hydrocarbon group, X is selected from a halide group and a:b:c is in range of 0.1-99.8 : 0.1-99.8 : 0.1-99.8, said process comprising contacting a magnesium source with an organohalide and an alcohol in a solvent to form the organomagnesium precursor, wherein the liquid organomagnesium precursor is synthesized through a single step; wherein the magnesium source is reacted with the organohalide in a molar ratio between 1:20 to 1:0.2 and the magnesium source along with organohalide is reacted with the alcohol in a molar ratio between 1:20 to 1:0.2.
A slider-equipped window glass comprising: a window glass mounted on a side door of a vehicle so as to be vertically movable up and down and having two sides, and a slider attached to a vehicle inner surface of at least one of said two sides of the window glass, along the up-and-down movement direction, and being movable up and down along an up-and-down movement guide member fixed to said side door, wherein said slider is an integrally molded product comprising an inner layer portion and an outer layer portion , said inner layer portion is bonded to said vehicle inner surface of the window glass , said outer layer portion is located at the vehicle inner surface side of the inner layer portion and made of a material harder than said inner layer portion, said outer layer portion has an engaging portion to engage with said up-and-down movement guide member , and said inner layer portion of the slider is made of a thermoplastic elastomer, and said outer layer portion is made of a thermoplastic elastomer containing fibers. a window glass mounted on a side door of a vehicle so as to be vertically movable up and down and having two sides, and a slider attached to a vehicle inner surface of at least one of said two sides of the window glass, along the up-and-down movement direction, and being movable up and down along an up-and-down movement guide member fixed to said side door, wherein said slider is an integrally molded product comprising an inner layer portion and an outer layer portion , said inner layer portion is bonded to said vehicle inner surface of the window glass , said outer layer portion is located at the vehicle inner surface side of the inner layer portion and made of a material harder than said inner layer portion, said outer layer portion has an engaging portion to engage with said up-and-down movement guide member , and said inner layer portion of the slider is made of a thermoplastic elastomer, and said outer layer portion is made of a thermoplastic elastomer containing fibers.
A method for enabling an applied key management operation at a client device, the method comprising: establishing a data connection with a file kernel driver of the client device to enable the applied key management operation; receiving from the file kernel driver a request pertaining to encryption key data; relaying the request pertaining to the encryption key data to an applied key management system ; and receiving a response to the request from the applied key management system based on at least one policy of the applied key management system , wherein the file kernel driver , the file kernel driver being a software module configured for providing configurations related to file access operations concerning the encryption key data, is configured to substitute a key file with a link to invoke the applied key management operation, and the link causes the applied key management operation to be executed in response to a file access operation being executed on an encryption key material. establishing a data connection with a file kernel driver of the client device to enable the applied key management operation; receiving from the file kernel driver a request pertaining to encryption key data; relaying the request pertaining to the encryption key data to an applied key management system ; and receiving a response to the request from the applied key management system based on at least one policy of the applied key management system , wherein the file kernel driver , the file kernel driver being a software module configured for providing configurations related to file access operations concerning the encryption key data, is configured to substitute a key file with a link to invoke the applied key management operation, and the link causes the applied key management operation to be executed in response to a file access operation being executed on an encryption key material.
An in vitro method to inhibit the DNA damage response in a mammalian cell damaged in at least one sequence-specific genomic locus, wherein the DNA damage occurs at telomeres and/or is caused by a sequence-specific DNA endonuclease, wherein the method comprises inhibiting the function and/or impairing the production of small RNAs (DDRNAs), said small RNAs being generated in cis by processing by DICER and/or DROSHA of a RNA transcript synthesized using the specific damaged genomic locus as template for transcription, wherein inhibiting the function of DDRNAs and/or impairing the production thereof is performed by a sequence-specific inhibitory oligonucleotide that specifically binds to said small RNAs (DDRNAs).
An air conditioning assembly for an environmental chamber , the air conditioning assembly comprising: - a suspended ceiling for suspending below a structural ceiling of the environmental chamber to create a plenum space therebetween, said suspended ceiling being configured to cover a substantially horizontal plane of the environmental chamber whilst leaving a first perimeter gap adjacent to a wall of the environmental chamber , and a second perimeter gap adjacent to an opposing wall of the environmental chamber ; - a substantially vertical wall for covering a vertical plane of the plenum space ; - at least one fan within the plenum space , said at least one fan being configured to draw air from one side of the substantially vertical wall to the other side, and therefore configured to draw air from the environmental chamber and into the plenum space through the first perimeter gap , and to blow air from the plenum space and into the environmental chamber through the second perimeter gap ; and, - at least one air conditioning means in fluid communication with the at least one fan , configured to condition the air flow passing through said at least one fan ; characterized in that the at least one air conditioning means comprises an altitude simulator for changing the oxygen content of the air flow, and the first perimeter gap and the second perimeter gap are configured such that they span along substantially the entire edge of the suspended ceiling such that, in use, the air conditioning assembly is configured to create substantially laminar air flow throughout the environmental chamber . - a suspended ceiling for suspending below a structural ceiling of the environmental chamber to create a plenum space therebetween, said suspended ceiling being configured to cover a substantially horizontal plane of the environmental chamber whilst leaving a first perimeter gap adjacent to a wall of the environmental chamber , and a second perimeter gap adjacent to an opposing wall of the environmental chamber ; - a substantially vertical wall for covering a vertical plane of the plenum space ; - at least one fan within the plenum space , said at least one fan being configured to draw air from one side of the substantially vertical wall to the other side, and therefore configured to draw air from the environmental chamber and into the plenum space through the first perimeter gap , and to blow air from the plenum space and into the environmental chamber through the second perimeter gap ; and, - at least one air conditioning means in fluid communication with the at least one fan , configured to condition the air flow passing through said at least one fan ;
A process comprising contacting 2-bromo-N-(2-bromobenzyl)-N-methylaniline with 2-((tetrahydro-2H-pyran-2-yl)oxy)-[1,1'-biphenyl]-3-yl lithium in a polar aprotic reaction medium under reaction conditions, thereby forming 2-(((2'-hydroxy-[1,1':3',1"-terphenyl]-2-yl)(methyl)amino)methyl)-[1,1':3',1"-terphenyl]-2'-ol.