mhurhangee/patent-ind-claim-en huggingface dataset:
A nucleic acid molecule comprising a nucleotide sequence, which encodes a miniaturized dystrophin polypeptide comprising from N terminus to C terminus hinge 1 (H1) domain, spectrin repeat 1 (R1) domain, spectrin repeat 3 (R3) domain, hinge 2 (H2) domain, spectrin repeat 16 (R16) domain, spectrin repeat 17 (R17) domain, spectrin repeat 24 (R24) domain, and hinge 4 (H4) domain of dystrophin, wherein the miniaturized dystrophin polypeptide does not comprise spectrin repeat 2 of dystrophin, wherein the R1 domain and the R3 domain are fused by amino acids ARG-VAL (RV) and wherein the H2 domain and the R16 domain are fused by the amino acid sequence set forth in SEQ ID NOs: 74-75 in combination, and wherein (i) the H1 domain and the R1 domain are fused directly, (ii) the R3 domain and the H2 domain are fused directly, (iii) the R16 and R17 domains are fused directly, (iv) the R17 and R24 domains are fused directly, and (v) the R24 and H4 domains are fused directly.
Endonasal drug delivery device suitable for inhalation by a patient comprising a shaped body having: - at least one first portion located at a first end of said shaped body , shaped to be inserted in a nasal cavity and having at least one air delivery duct towards the nasal cavity; - at least one second intermediate portion having at least one supply duct to allow the air inflow from the outside towards the inside of said endonasal delivery device ; - at least one third portion located at the opposite end of said first portion and comprising at least one mixing chamber , wherein said mixing chamber is in fluid communication with: - said at least one supply duct to receive air from the outside; - at least one drug reservoir separated from said mixing chamber and in fluid connection with it to allow the drugs to flow into said mixing chamber to be drawn from the air by disturbance; - said at least one delivery duct for allowing the flow of drugs mixed with air into the nasal cavity, said fluid communication identifying a fluidic path that provides the air to inflow from the outside towards the inside of said endonasal delivery device by said supply duct , then walking towards said one mixing chamber , then collect the drugs by disturbance, so the drugs flow to said mixing chamber by the pressure differential between said mixing chamber and said reservoir and finally the mix air-drugs flows towards said delivery duct towards the nasal cavity. - at least one first portion located at a first end of said shaped body , shaped to be inserted in a nasal cavity and having at least one air delivery duct towards the nasal cavity; - at least one second intermediate portion having at least one supply duct to allow the air inflow from the outside towards the inside of said endonasal delivery device ; - at least one third portion located at the opposite end of said first portion and comprising at least one mixing chamber , wherein said mixing chamber is in fluid communication with: - said at least one supply duct to receive air from the outside; - at least one drug reservoir separated from said mixing chamber and in fluid connection with it to allow the drugs to flow into said mixing chamber to be drawn from the air by disturbance; - said at least one delivery duct for allowing the flow of drugs mixed with air into the nasal cavity, - said at least one supply duct to receive air from the outside; - at least one drug reservoir separated from said mixing chamber and in fluid connection with it to allow the drugs to flow into said mixing chamber to be drawn from the air by disturbance; - said at least one delivery duct for allowing the flow of drugs mixed with air into the nasal cavity, said fluid communication identifying a fluidic path that provides the air to inflow from the outside towards the inside of said endonasal delivery device by said supply duct , then walking towards said one mixing chamber , then collect the drugs by disturbance, so the drugs flow to said mixing chamber by the pressure differential between said mixing chamber and said reservoir and finally the mix air-drugs flows towards said delivery duct towards the nasal cavity.
A method for manufacturing of steel articles, comprising the steps of: nitriding a steel article at a nitrification temperature in the interval 350-650°C; said step of nitriding a steel article resulting in a nitrided steel article; and quenching said nitrided steel article in a quenching oil from said nitrification temperature, characterized in that said quenching oil being a reactive quenching oil, containing one or more surface-reactive compounds serving as carriers of at least one of S, P, B, Mo and W; whereby said step of quenching additionally comprises coating of said nitrided steel article by a solid lubricant comprising at least one of S, P, B, Mo and W; said reactive quenching oil comprises at least 0.1% of weight of the total of S, P, B, Mo and W; said reactive quenching oil comprises at most 10% of weight of the total of S, P, B, Mo and W; and by the further step of: maintaining said nitrided steel article in an atmosphere of a nitrogen potential prohibiting de-nitriding an entire time between said step of nitriding and said step of quenching . nitriding a steel article at a nitrification temperature in the interval 350-650°C; said step of nitriding a steel article resulting in a nitrided steel article; and quenching said nitrided steel article in a quenching oil from said nitrification temperature, said quenching oil being a reactive quenching oil, containing one or more surface-reactive compounds serving as carriers of at least one of S, P, B, Mo and W; whereby said step of quenching additionally comprises coating of said nitrided steel article by a solid lubricant comprising at least one of S, P, B, Mo and W; said reactive quenching oil comprises at least 0.1% of weight of the total of S, P, B, Mo and W; said reactive quenching oil comprises at most 10% of weight of the total of S, P, B, Mo and W;
An apparatus comprising: a processor; a memory that stores code executable by the processor, the code comprising: code adapted to determine a data bandwidth limitation of a network connection of a first electronic device, wherein the first electronic device is a smart phone being setup as a mobile hotspot; code adapted to receive a request from a second electronic device to access the network connection of the first electronic device; code adapted to provide data corresponding to the data bandwidth limitation to the second electronic device in response to receiving the request from the second electronic device to access the network connection code adapted to determine a metering level for data provided to the second electronic device; code adapted to monitor an amount of data used by the second electronic device; and code adapted to limit the amount of data used by the second electronic device depending on how much data bandwidth has been used prior to the second electronic device using the network connection of the first electronic device according to the determined metering level. a processor; a memory that stores code executable by the processor, the code comprising: code adapted to determine a data bandwidth limitation of a network connection of a first electronic device, wherein the first electronic device is a smart phone being setup as a mobile hotspot; code adapted to receive a request from a second electronic device to access the network connection of the first electronic device; code adapted to provide data corresponding to the data bandwidth limitation to the second electronic device in response to receiving the request from the second electronic device to access the network connection code adapted to determine a metering level for data provided to the second electronic device; code adapted to monitor an amount of data used by the second electronic device; and code adapted to limit the amount of data used by the second electronic device depending on how much data bandwidth has been used prior to the second electronic device using the network connection of the first electronic device according to the determined metering level. code adapted to determine a data bandwidth limitation of a network connection of a first electronic device, wherein the first electronic device is a smart phone being setup as a mobile hotspot; code adapted to receive a request from a second electronic device to access the network connection of the first electronic device; code adapted to provide data corresponding to the data bandwidth limitation to the second electronic device in response to receiving the request from the second electronic device to access the network connection code adapted to determine a metering level for data provided to the second electronic device; code adapted to monitor an amount of data used by the second electronic device; and code adapted to limit the amount of data used by the second electronic device depending on how much data bandwidth has been used prior to the second electronic device using the network connection of the first electronic device according to the determined metering level.
A quick vehicle check system adopting multi-dose regional scanning for scanning a vehicle with a cab and a carriage, the system comprising: a radiation source configured to produce a first X ray with a first dose and a second X ray with a second dose, wherein the first dose is smaller than the second dose, and the first X ray is used for checking a first part of the checked vehicle having a predetermined distance and the second X ray is used for checking a second part of the checked vehicle; a first sensor configured to detect a set position of the checked vehicle; a second sensor configured to detect the passing distance of the checked vehicle which is a distance travelled by the checked vehicle since the detection of the set position of the checked vehicle; and a control unit coupled with the first sensor and the second sensor, configured to receive the set position of the checked vehicle from the first sensor and receive the passing distance of the checked vehicle from the second sensor, wherein the set position of the checked vehicle is the rear edge of a cab, front edge of a carriage or an arbitrary position therebetween and when it is determined that the set position of the checked vehicle reaches a scanning region, the control unit informs the radiation source to emit the first X ray such that the vehicle is scanned with the first X-ray immediately behind the cab; and when the passing distance of the checked vehicle reaches the predetermined distance, the control unit informs the radiation source to emit the second X ray so as to scan the second part. a radiation source configured to produce a first X ray with a first dose and a second X ray with a second dose, wherein the first dose is smaller than the second dose, and the first X ray is used for checking a first part of the checked vehicle having a predetermined distance and the second X ray is used for checking a second part of the checked vehicle; a first sensor configured to detect a set position of the checked vehicle; a second sensor configured to detect the passing distance of the checked vehicle which is a distance travelled by the checked vehicle since the detection of the set position of the checked vehicle; and a control unit coupled with the first sensor and the second sensor, configured to receive the set position of the checked vehicle from the first sensor and receive the passing distance of the checked vehicle from the second sensor, wherein the set position of the checked vehicle is the rear edge of a cab, front edge of a carriage or an arbitrary position therebetween and when it is determined that the set position of the checked vehicle reaches a scanning region, the control unit informs the radiation source to emit the first X ray such that the vehicle is scanned with the first X-ray immediately behind the cab; and when the passing distance of the checked vehicle reaches the predetermined distance, the control unit informs the radiation source to emit the second X ray so as to scan the second part.
A fireproof and non-toxic decorative panel for interior and/or exterior use, characterised in that it includes a first layer formed by a layer of iron oxides and mortars applied manually in a horizontal and transverse manner, forming a compact block, wherein the exposed face thereof incorporates the shape and/or motif of the decorative element and wherein there are added to said layer a second layer formed by a water-based acrylic polymer mixture mixed with calcium sulphate hemihydrate (CaSO 4 0.5H 2 O a third layer formed by a triaxial glass fibre sheet, and finally a fourth layer formed by the water-based acrylic polymer mixture mixed with calcium sulphate hemihydrate (CaSO 4 0.5H 2 O).
A lawn maintenance vehicle having a park brake and traction drive interlock comprising: a park brake mechanism mounted to said lawn maintenance vehicle , said park brake mechanism is selectively operable between an engaged position and a disengaged position; a traction drive mounted to said lawn maintenance vehicle , wherein said traction drive is a hydrostatic traction drive and comprises a disable mode which prohibits transmission of a driving force from said traction drive to a drive wheel of said lawn maintenance vehicle ; a first operable connection between said park brake mechanism and a wheel brake, wherein when said park brake mechanism is in the engaged position, said first operable connection activates said wheel brake; and a second operable connection between said park brake mechanism and said traction drive , wherein when said park brake mechanism is in the engaged position, said second operable connection activates said disable mode of said traction drive , characterized by comprising a sensor , which detects the activation of said disable mode of said traction drive , wherein said sensor is in electrical communication with a vehicle start system , wherein when said park brake mechanism is located in the engaged position, said vehicle start system is activated, and wherein said sensor is in electrical communication with a vehicle operator presence control , wherein when said park brake mechanism is located in the engaged position, said vehicle operator presence control is deactivated. a park brake mechanism mounted to said lawn maintenance vehicle , said park brake mechanism is selectively operable between an engaged position and a disengaged position; a traction drive mounted to said lawn maintenance vehicle , wherein said traction drive is a hydrostatic traction drive and comprises a disable mode which prohibits transmission of a driving force from said traction drive to a drive wheel of said lawn maintenance vehicle ; a first operable connection between said park brake mechanism and a wheel brake, wherein when said park brake mechanism is in the engaged position, said first operable connection activates said wheel brake; and a second operable connection between said park brake mechanism and said traction drive , wherein when said park brake mechanism is in the engaged position, said second operable connection activates said disable mode of said traction drive , characterized by comprising a sensor , which detects the activation of said disable mode of said traction drive , wherein said sensor is in electrical communication with a vehicle start system , wherein when said park brake mechanism is located in the engaged position, said vehicle start system is activated, and wherein said sensor is in electrical communication with a vehicle operator presence control , wherein when said park brake mechanism is located in the engaged position, said vehicle operator presence control is deactivated.
A peptide consisting of the amino acid sequence of any one of GLYSTVPHNV (SEQ ID NO: 1, TVLPGLTYL (SEQ ID NO: 3) and VLIQQLEKA (SEQ ID NO: 4), wherein the polypeptide forms a complex with a Major Histocompatibility Complex (MHC) molecule.
A multimodal sensor for detecting a temperature or a position on the sensor where a pressure is applied, comprising a plurality of first conductive electrodes that are arranged along a direction parallel with one another and spaced from one another with a certain distance, an insulating layer that is formed on the first conductive electrodes , a plurality of second conductive electrodes that are formed on the other side of the insulating layer than the first electrodes along a direction crossing the direction of the first conductive electrodes and parallel with one another and spaced from one another, a first substrate that is formed on a bottom portion of the first conductive electrodes , a second substrate formed on a top portion of the second conductive electrodes , and a controller configured to apply voltages to the first and second conductive electrodes and to detect capacitance formed between the first and second conductive electrodes for detecting an external temperature or a position where a pressure is applied in response to a variation of the capacitance, wherein the insulating layer is formed of any one of polydimethylsiloxane (PDMS), polyurethane (PU) and polyethylene phthalate (PET), characterized in that the first conductive electrodes and the second conductive electrodes are made of carbon nanotube fibers manufactured by winding a carbon nanotube film by means of a motor.
Alight emitting diode, comprising: a first electrode ; an active layer on the first electrode ; and a second electrode on a side of the active layer away from the first electrode , wherein the second electrode comprises a first conductive layer and a second conductive layer sequentially arranged along a direction away from the active layer , the first conductive layer comprises a plurality of micropores ; the second conductive layer comprises a plurality of conductive nanoparticles , and at least a part of the plurality of conductive nanoparticles is in contact with the active layer through the plurality of micropores , which is characterized in that , a material of the first conductive layer comprises aluminum, and a material of the second conductive layer comprises silver. a first electrode ; an active layer on the first electrode ; and a second electrode on a side of the active layer away from the first electrode , wherein the second electrode comprises a first conductive layer and a second conductive layer sequentially arranged along a direction away from the active layer , the first conductive layer comprises a plurality of micropores ; the second conductive layer comprises a plurality of conductive nanoparticles , and at least a part of the plurality of conductive nanoparticles is in contact with the active layer through the plurality of micropores , which is characterized in that , a material of the first conductive layer comprises aluminum, and a material of the second conductive layer comprises silver.
A method for analysis of target nucleic acid, the method comprising the following steps: i. in a sample that has been provided and wherein target nucleic acids are present in an amount of 100 pg or less, wherein said target nucleic acids originate from an embryo or fetus or from a cancer or tumor cell, ii. generating a reduced representation library of said target nucleic acids by a method comprising • fragmenting said target nucleic acids using one or more restriction enzymes; • ligating adaptors to said fragments; and • selecting a subset of said adaptor-ligated fragments based on the size of said fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said target nucleic acids by analyzing results obtained by said sequencing. i. in a sample that has been provided and wherein target nucleic acids are present in an amount of 100 pg or less, wherein said target nucleic acids originate from an embryo or fetus or from a cancer or tumor cell, ii. generating a reduced representation library of said target nucleic acids by a method comprising • fragmenting said target nucleic acids using one or more restriction enzymes; • ligating adaptors to said fragments; and • selecting a subset of said adaptor-ligated fragments based on the size of said fragments, • fragmenting said target nucleic acids using one or more restriction enzymes; • ligating adaptors to said fragments; and • selecting a subset of said adaptor-ligated fragments based on the size of said fragments, iii. massively parallel sequencing said reduced representation library, and iv. identifying variants in said target nucleic acids by analyzing results obtained by said sequencing.
An agricultural vehicle comprising an operator environment having a roof portion , and an air treatment apparatus installed within the roof portion, wherein the air treatment apparatus comprises: a vehicle HVAC system having an inlet plenum, other HVAC components and an outlet to the operator environment; and an air filtration system having at least one external inlet and first and second filtration devices located in an air flow path between the at least one external inlet and the HVAC inlet plenum; wherein the roof portion is a hollow structure having upper and lower surfaces and front, rear, left and right sidewalls; the vehicle characterised by ; the first and second filtration devices both being disposed along a same one of the left and right sidewalls and the HVAC system being disposed along the rear sidewall within the hollow structure of the roof portion ; the air filtration system comprising a valve mechanism operative to selectively connect either the first filtration device to the HVAC inlet plenum or the second filtration device to the HVAC inlet plenum; the air treatment apparatus comprising a first blower connecting the filtration devices and the HVAC system inlet plenum, the first blower being connected to each of the filtration devices by a respective duct and a second blower configured to produce a higher throughput of air than the first blower , the inlet of the second blower being connected in series with the outlet of the first blower , the second blower being disposed adjacent one of the first and second filtration devices . a vehicle HVAC system having an inlet plenum, other HVAC components and an outlet to the operator environment; and an air filtration system having at least one external inlet and first and second filtration devices located in an air flow path between the at least one external inlet and the HVAC inlet plenum; wherein the roof portion is a hollow structure having upper and lower surfaces and front, rear, left and right sidewalls; the vehicle characterised by ; the first and second filtration devices both being disposed along a same one of the left and right sidewalls and the HVAC system being disposed along the rear sidewall within the hollow structure of the roof portion ; the air filtration system comprising a valve mechanism operative to selectively connect either the first filtration device to the HVAC inlet plenum or the second filtration device to the HVAC inlet plenum; the air treatment apparatus comprising a first blower connecting the filtration devices and the HVAC system inlet plenum, the first blower being connected to each of the filtration devices by a respective duct and a second blower configured to produce a higher throughput of air than the first blower , the inlet of the second blower being connected in series with the outlet of the first blower , the second blower being disposed adjacent one of the first and second filtration devices .