mhurhangee/patent-ind-claim-en huggingface dataset:
A method for searching for a modification site of a peptide molecule, the method comprising: calculating, by a computer, a second steric structure of the peptide molecule by using data of a first steric structure of the peptide molecule, the first steric structure being a steric structure of the peptide molecule in a complex structure of a target molecule and the peptide molecule, the second steric structure being a stable steric structure of the peptide molecule in a state where a steric configuration of a main chain of the peptide molecule in the first steric structure is fixed; and comparing data of the second steric structure with the data of the first steric structure in order to search for a side chain having a difference in steric configuration between the two steric structures, and determining the side chain as the modification site, the method further comprising: calculating the second steric structure by performing a ground state search using an annealing method for an Ising model converted based on a restriction condition of a side chain of the peptide molecule to calculate a minimum energy of the Ising model so that the calculation of the second steric structure is reduced to a combinatorial optimization problem of steric configurations of the side chains. calculating, by a computer, a second steric structure of the peptide molecule by using data of a first steric structure of the peptide molecule, the first steric structure being a steric structure of the peptide molecule in a complex structure of a target molecule and the peptide molecule, the second steric structure being a stable steric structure of the peptide molecule in a state where a steric configuration of a main chain of the peptide molecule in the first steric structure is fixed; and comparing data of the second steric structure with the data of the first steric structure in order to search for a side chain having a difference in steric configuration between the two steric structures, and determining the side chain as the modification site, the method further comprising: calculating the second steric structure by performing a ground state search using an annealing method for an Ising model converted based on a restriction condition of a side chain of the peptide molecule to calculate a minimum energy of the Ising model so that the calculation of the second steric structure is reduced to a combinatorial optimization problem of steric configurations of the side chains.
A method of performing cell reselection by a wireless communications device , the method comprising: measuring a signal strength of radio signals received from a serving cell , determining whether the signal strength of the signals received from the serving cell is lower than a first predetermined signal strength threshold, if the signal strength is lower than the first predetermined signal strength threshold measuring signals received from a neighbour cell operating on the same frequency as the serving cell to generate neighbour cell measurements at a first rate, and in accordance with the neighbour cell measurements of the neighbour cell generated at the first rate determining whether to reselect to the neighbour cell, and if the signal strength of the signals received from the serving cell is greater than the first predetermined signal strength threshold and the radio signals received from the serving cell satisfy one or more predetermined conditions based on at least one of the measured signal strength of the signals received from the serving cell and a measured signal quality of the signals received from the serving cell, measuring the signals received from the neighbour cell to generate neighbour cell measurements at a second rate, and in accordance with the neighbour cell measurements of the neighbour cell generated at the second rate determining whether to reselect to the neighbour cell, wherein the second rate is less than the first rate. measuring a signal strength of radio signals received from a serving cell , determining whether the signal strength of the signals received from the serving cell is lower than a first predetermined signal strength threshold, if the signal strength is lower than the first predetermined signal strength threshold measuring signals received from a neighbour cell operating on the same frequency as the serving cell to generate neighbour cell measurements at a first rate, and in accordance with the neighbour cell measurements of the neighbour cell generated at the first rate determining whether to reselect to the neighbour cell, and if the signal strength of the signals received from the serving cell is greater than the first predetermined signal strength threshold and the radio signals received from the serving cell satisfy one or more predetermined conditions based on at least one of the measured signal strength of the signals received from the serving cell and a measured signal quality of the signals received from the serving cell, measuring the signals received from the neighbour cell to generate neighbour cell measurements at a second rate, and in accordance with the neighbour cell measurements of the neighbour cell generated at the second rate determining whether to reselect to the neighbour cell, wherein the second rate is less than the first rate.
A hemodialysis machine defining a closed loop fluid path for dialysate solution, the fluid path comprising: a first pump chamber having a pump inlet and a pump outlet; a dialyser having a dialyser inlet and a dialyser outlet ; a conduit connected between the outlet of the first pump chamber and the inlet of the dialyser; a second pump chamber having a pump inlet and a pump outlet; a conduit connected between the outlet of the dialyser and the inlet of the second pump chamber; a dialysate regeneration device having an inlet and an outlet ; a conduit connected between the outlet of the second pump chamber and the inlet of the dialysate regeneration device; a reservoir having a reservoir inlet and a reservoir outlet ; a conduit connected between the outlet of the dialysate regeneration device and the inlet of the reservoir ; and, a conduit connected between the outlet of the reservoir and the inlet of the first pump chamber, characterized in that the reservoir comprises a housing defining a continuous side wall , a top , a bottom , the inlet of the reservoir and the outlet of the reservoir , and an overflow device mounted therein. a first pump chamber having a pump inlet and a pump outlet; a dialyser having a dialyser inlet and a dialyser outlet ; a conduit connected between the outlet of the first pump chamber and the inlet of the dialyser; a second pump chamber having a pump inlet and a pump outlet; a conduit connected between the outlet of the dialyser and the inlet of the second pump chamber; a dialysate regeneration device having an inlet and an outlet ; a conduit connected between the outlet of the second pump chamber and the inlet of the dialysate regeneration device; a reservoir having a reservoir inlet and a reservoir outlet ; a conduit connected between the outlet of the dialysate regeneration device and the inlet of the reservoir ; and, a conduit connected between the outlet of the reservoir and the inlet of the first pump chamber, characterized in that the reservoir comprises a housing defining a continuous side wall , a top , a bottom , the inlet of the reservoir and the outlet of the reservoir , and an overflow device mounted therein.
Document (DC1), comprising: - a stack of layers comprising at least one upper layer (LY1), one lower layer (LY3) and one inner layer (LY2) which is interposed between the upper layer and the lower layer, the inner layer being transparent or translucent so as to form a waveguide to guide light (LG1) in a first wavelength spectrum (SP1) through the inner layer, the inner layer forming, collectively with the upper layer and the lower layer, an edge which delimits an outline of the stack; and - an array of lenses ; the document being characterized in that the lenses are formed on at least part of the edge of the stack , said lenses being positioned along the edge in order to make the light (LG1) in the first wavelength spectrum converge or diverge when it propagates through the inner layer until it emerges from the document through said edge , so as to make a series of coloured zones (Z1, Z2) of at least two distinct colours (C1, C2, C4) appear on the edge. - a stack of layers comprising at least one upper layer (LY1), one lower layer (LY3) and one inner layer (LY2) which is interposed between the upper layer and the lower layer, the inner layer being transparent or translucent so as to form a waveguide to guide light (LG1) in a first wavelength spectrum (SP1) through the inner layer, the inner layer forming, collectively with the upper layer and the lower layer, an edge which delimits an outline of the stack; and - an array of lenses ; - an array of lenses ; the document being characterized in that the lenses are formed on at least part of the edge of the stack , said lenses being positioned along the edge in order to make the light (LG1) in the first wavelength spectrum converge or diverge when it propagates through the inner layer until it emerges from the document through said edge , so as to make a series of coloured zones (Z1, Z2) of at least two distinct colours (C1, C2, C4) appear on the edge.
A system for balloon inflation , the system comprising: a catheter having an inflow lumen and an outflow lumen ; a balloon positioned at a distal end of the catheter, the balloon being in fluid communication with the inflow and the outflow lumen; an infusion device in fluid communication with the balloon through the inflow and outflow lumens, the infusion device configured for continuously circulating a fluid into and out of the balloon via the inflow lumen and the outflow lumen at matching flow rates in order to keep the balloon volume and pressure constant during an entire infusion; wherein the infusion device comprises: an inflow chamber being in fluid communication with the balloon via the inflow lumen ; and an outflow chamber being in fluid communication with the balloon via the outflow lumen wherein the inflow chamber and outflow chamber each comprise: a piston , wherein each piston is configured to control the volume of fluid in the respective inflow chamber or outflow chamber; and an associated drive mechanism ; and wherein the inflow and outflow chambers are mechanically linked via their drive mechanisms so that, once the balloon is inflated, each piston has a movement that is equal and opposite to the other piston . a catheter having an inflow lumen and an outflow lumen ; a balloon positioned at a distal end of the catheter, the balloon being in fluid communication with the inflow and the outflow lumen; an infusion device in fluid communication with the balloon through the inflow and outflow lumens, the infusion device configured for continuously circulating a fluid into and out of the balloon via the inflow lumen and the outflow lumen at matching flow rates in order to keep the balloon volume and pressure constant during an entire infusion; wherein the infusion device comprises: an inflow chamber being in fluid communication with the balloon via the inflow lumen ; and an outflow chamber being in fluid communication with the balloon via the outflow lumen an inflow chamber being in fluid communication with the balloon via the inflow lumen ; and an outflow chamber being in fluid communication with the balloon via the outflow lumen wherein the inflow chamber and outflow chamber each comprise: a piston , wherein each piston is configured to control the volume of fluid in the respective inflow chamber or outflow chamber; and an associated drive mechanism ; a piston , wherein each piston is configured to control the volume of fluid in the respective inflow chamber or outflow chamber; and an associated drive mechanism ; and wherein the inflow and outflow chambers are mechanically linked via their drive mechanisms so that, once the balloon is inflated, each piston has a movement that is equal and opposite to the other piston .
A compound of Formula (I): in the form of a hemisulfate salt.
A method for producing a spatially varied separation medium, the method comprising: exposing a separation medium precursor solution to light from a light source through a photomask comprising a semi-transparent region with varied light transmittance to produce the separation medium, wherein the photomask includes a grid pattern of an opaque material on a surface of an optically transmissive substrate, wherein the photomask is a gradient photomask that comprises a region of low light transmission and a region of high light transmission with an increasing light transmission from the region of low light transmission to the region of high light transmission. exposing a separation medium precursor solution to light from a light source through a photomask comprising a semi-transparent region with varied light transmittance to produce the separation medium, wherein the photomask includes a grid pattern of an opaque material on a surface of an optically transmissive substrate, wherein the photomask is a gradient photomask that comprises a region of low light transmission and a region of high light transmission with an increasing light transmission from the region of low light transmission to the region of high light transmission.
Sawing machine with a machining table and with a lifting device for a saw blade for processing workpieces made of wood, plastic, and the like, with a crank drive which has a crank , and with a push rod which is connected to a saw blade holder supporting the saw blade and is coupled to a transmission ratio , via which the crank is connected to the saw blade holder and which has a two-armed lever which is pivotable about a pivot axis , wherein the saw blade is a circular saw blade , and the saw blade holder is displaceable using the crank from an idle position, in which the circular saw blade is arranged underneath the machining table , into a working position, in which the circular saw blade processes the workpieces located on the machining table , characterized in that the lever arms of the two-armed lever are at an obtuse angle to one another, the pivot axis lies in the V-tip of the two-armed lever , the crank is hinged to the one lever arm , and the other lever arm for hinging the push rod has at least two connections , which have different distances from the pivot axis of the two-armed lever .
A vehicle steering angle detecting apparatus that connects a motor , which assist-controls a steering system of a vehicle, to a steering shaft via a reduction mechanism , and comprises a first angle sensor to detect a steering shaft angle of said steering shaft and a second angle sensor to detect a motor shaft angle of said motor , characterised in that the vehicle steering angle detecting apparatus further comprises: a function that updates a static characteristic map and a dynamic characteristic map by iteratively learning a static characteristic and a dynamic characteristic of nonlinear elements which include said reduction mechanism , and mutually estimates said steering shaft angle and said motor shaft angle by using said static characteristic map and said dynamic characteristic map .
A needleless valve system comprising a housing comprising a fluid port and a lower volume ; and a valve (100A-C) disposed in said housing , wherein said valve (100A-C) comprises: a body configured to be disposed in said needleless valve system and controlling fluid flow through said needleless valve system, wherein said body does not include a tail that protrudes down from the body toward the lower volume , said body comprising: a top surface comprising a smooth surface that is unbroken,; a retaining flange retaining the valve (100A-C) within the housing ; and a compression feature being a portion of a wall of the body , wherein a wall thickness of the compression feature is greater than a wall thickness of said wall proximate to the compression feature , wherein the compression feature is asymmetric along a center cross-section of the body ; and wherein said fluid port is fluidically sealed by an outer surface of the valve (100A-C) against an inner wall of the housing ; characterized in that the top surface of the body deforms based on the compression feature into a V-shape when a needleless device pushes down on the top surface and thereby the valve is deformed such that the port is unsealed. a top surface comprising a smooth surface that is unbroken,; a retaining flange retaining the valve (100A-C) within the housing ; and a compression feature being a portion of a wall of the body , wherein a wall thickness of the compression feature is greater than a wall thickness of said wall proximate to the compression feature , wherein the compression feature is asymmetric along a center cross-section of the body ; and
A display screen for an electronic device , comprising: a functional area configured to achieve a function of the electronic device and comprising a plurality of pixel points , the plurality of pixel points defining a gap area therebetween; and a signal emitter received in the gap area , wherein the display screen further comprises a switch coupled to the signal emitter and at least one of the plurality of pixel points , the gap area is further provided with a signal receiver therein, the signal emitter is configured to emit a detecting signal and the signal receiver is configured to receive a reflected signal generated by the detecting signal being reflected by an external object, the signal emitter is an infrared emitter and the signal receiver is an infrared receiver, characterized in that the switch is configured to turn on the signal emitter and turn off the at least one of the plurality of pixel points when receiving a first drive signal, and the switch is further configured to turn on the at least one of the plurality of pixel points and turn off the signal emitter when receiving a second drive signal, wherein the first drive signal is received when the display screen enters into an object sensing mode and the second drive signal is received when the display screen enters into a display mode. a functional area configured to achieve a function of the electronic device and comprising a plurality of pixel points , the plurality of pixel points defining a gap area therebetween; and a signal emitter received in the gap area , wherein the display screen further comprises a switch coupled to the signal emitter and at least one of the plurality of pixel points , the gap area is further provided with a signal receiver therein, the signal emitter is configured to emit a detecting signal and the signal receiver is configured to receive a reflected signal generated by the detecting signal being reflected by an external object, the signal emitter is an infrared emitter and the signal receiver is an infrared receiver, characterized in that the switch is configured to turn on the signal emitter and turn off the at least one of the plurality of pixel points when receiving a first drive signal, and the switch is further configured to turn on the at least one of the plurality of pixel points and turn off the signal emitter when receiving a second drive signal, wherein the first drive signal is received when the display screen enters into an object sensing mode and the second drive signal is received when the display screen enters into a display mode.
A grinding cavity body of multiple vibration sources, comprising an abrasive slurry; a cavity body , configured to contain the abrasive slurry; and a plurality of ultrasonic vibration sources, with vibration frequencies and amplitudes that can be adjusted during a grinding process, disposed on a bottom of the cavity body , characterized in that the plurality of ultrasonic vibration sources are classified as at least a strong ultrasonic vibration source and weak ultrasonic vibration sources according to vibration frequencies, and the weak ultrasonic vibration sources are disposed farther from a center or a middle of the bottom of the cavity body than the at least a strong ultrasonic vibration source ; wherein the at least a strong ultrasonic vibration source and the plurality of weak ultrasonic vibration sources respectively generate ultrasonic vibrations in two different frequencies to make the abrasive slurry flow upward from the bottom of the cavity body and spread out from the center of the cavity body ; wherein the weak ultrasonic vibration sources have a lower vibration frequency than the at least a strong ultrasonic vibration source. a cavity body , configured to contain the abrasive slurry; and a plurality of ultrasonic vibration sources, with vibration frequencies and amplitudes that can be adjusted during a grinding process, disposed on a bottom of the cavity body , characterized in that the plurality of ultrasonic vibration sources are classified as at least a strong ultrasonic vibration source and weak ultrasonic vibration sources according to vibration frequencies, and the weak ultrasonic vibration sources are disposed farther from a center or a middle of the bottom of the cavity body than the at least a strong ultrasonic vibration source ; wherein the at least a strong ultrasonic vibration source and the plurality of weak ultrasonic vibration sources respectively generate ultrasonic vibrations in two different frequencies to make the abrasive slurry flow upward from the bottom of the cavity body and spread out from the center of the cavity body ; wherein the weak ultrasonic vibration sources have a lower vibration frequency than the at least a strong ultrasonic vibration source.
Device for producing a workpiece of a predetermined type, particularly of a hot-rolled material, comprising at least one first jet nozzle arrangement (14; 14.1) with a plurality of jet nozzles , from which a liquid , particularly water, can be applied to a surface of the workpiece under high pressure so as to thereby descale the workpiece , and a control device , characterised in that a data memory connected with a control device on a signal basis (23.4) is provided, wherein target data of a surface process model for the workpiece in accordance with at least one predetermined type can be stored in the data memory , wherein a specific energy intake (E), which for the descaling acts on a surface of the workpiece through the liquid sprayed from the jet nozzles , is controllable, preferably regulable, by means of the control device in dependence on the target data of the surface process model for the predetermined type of workpiece in such a way that the specific energy intake (E) and in connection therewith a temperature drop for the workpiece each assume a minimum value.