mhurhangee/patent-ind-claim-en huggingface dataset:
A bone material dispensing system comprising a loading device having a perimeter surrounding a base plane and a rim , the perimeter comprising a side wall extending along a longitudinal axis (LLA) and a bar joining the side wall at a corner of the perimeter and extending in a direction transverse to the longitudinal axis (LLA), the base plane comprising a loading surface bordering the side wall along the longitudinal axis (LLA), the loading surface having an end edge extending in a direction transverse to the longitudinal axis (LLA) such that the side wall , the bar and the end edge form the rim adjacent to the loading surface and the bar , wherein the bar comprises a bar surface bordering the side wall , characterised in that a bar ridge divides the bar surface into two portions.
Air guidance device for a vehicle front , with a respective air guidance element , which is located in a transitional region between a front region and a side region (15 of the vehicle front and can be moved from a retracted into at least one extended position, wherein the air guidance element forms in the extended position together with a trim element of the vehicle front a flow passage , by means of which an air flow flowing across the transitional region between the front region and the side region of the vehicle front can be diverted, and wherein the flow passage is at least substantially blocked in the retracted position of the air guidance element , characterised in that the air guidance element adjoins with a rear end edge a wheel well of an associated front wheel , and in that , by moving the air guidance element into the extended position, an opening terminating into the wheel well in the region of a front outer edge of the wheel well or a flow passage terminating into the wheel well is opened, through which opening or flow passage an air flow can be guided.
Compound of formula (I) wherein: n is 0, 1, 2, 3 or 4 m is 0 or 1, R 1 and R 2 form together and with the carbon atoms linked thereto an aryl group, preferably a substituted or non-substituted phenyl group, thereby forming a quinoline structure, R 3 and R 4 are independently selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, CF 3 and an aryl group, R 5 is selected from the group consisting of a hydrogen atom, an alkyl group and an acyl group, R 6 is a hydrogen atom or an alkyl group, when present, and R 7 is selected from the group consisting of a hydrogen atom, a NH 2 group and a CF 3 group. n is 0, 1, 2, 3 or 4 m is 0 or 1, R 1 and R 2 form together and with the carbon atoms linked thereto an aryl group, preferably a substituted or non-substituted phenyl group, thereby forming a quinoline structure, R 3 and R 4 are independently selected from the group consisting of a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, CF 3 and an aryl group, R 5 is selected from the group consisting of a hydrogen atom, an alkyl group and an acyl group, R 6 is a hydrogen atom or an alkyl group, when present, and R 7 is selected from the group consisting of a hydrogen atom, a NH 2 group and a CF 3 group.
Print head for a printing device for the three-dimensional application of a material, comprising - a heated nozzle for melting the material and for dispensing the melted material , - wherein the print head is designed to apply, as said print head moves along a predefined direction of travel (V), the melted material in the form of a strand on a previously applied material , which has at least partly solidified, and/or on a substrate , wherein - the print head has a melting facility , - wherein the melting facility is designed to continuously apply heat locally to respective regions of the previously applied material , as the print head is moving, wherein the melting facility has an optical element for guiding laser light, characterised in that the print head has an annular lens , which surrounds the nozzle , as the optical element . - a heated nozzle for melting the material and for dispensing the melted material , - wherein the print head is designed to apply, as said print head moves along a predefined direction of travel (V), the melted material in the form of a strand on a previously applied material , which has at least partly solidified, and/or on a substrate , - the print head has a melting facility , - wherein the melting facility is designed to continuously apply heat locally to respective regions of the previously applied material , as the print head is moving, wherein the melting facility has an optical element for guiding laser light, characterised in that the print head has an annular lens , which surrounds the nozzle , as the optical element . wherein the melting facility has an optical element for guiding laser light, characterised in that the print head has an annular lens , which surrounds the nozzle , as the optical element .
A pharmaceutical composition containing, as active principles, aprocitentan, or a pharmaceutically acceptable salt thereof, in combination with: • an angiotensin receptor blocker, or a pharmaceutically acceptable salt thereof; • a calcium channel blocker, or a pharmaceutically acceptable salt thereof; and • a diuretic which is hydrochlorothiazide; as well as at least one pharmaceutically acceptable excipient. • an angiotensin receptor blocker, or a pharmaceutically acceptable salt thereof; • a calcium channel blocker, or a pharmaceutically acceptable salt thereof; and • a diuretic which is hydrochlorothiazide;
A solid pharmaceutical formulation comprising a therapeutic agent and one or more pharmaceutically acceptable excipients, wherein the therapeutic agent is N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide: or its salt, or a combination thereof, and wherein the one or more pharmaceutically acceptable excipients are selected from sodium starch glycolate, carmellose, carmellose calcium, croscarmellose sodium, low-substituted hydroxypropylcellulose, and a combination thereof.
A process for the preparation of compound of Formula (I) and its pharmaceutically acceptable salts: wherein: R 1 is selected from the group consisting of halogen, alkyl having 1 to 2 carbon atoms, phenylalkynyl- having 2 to 3 carbon atoms in the alkynyl chain, phenyl-alkenyl- having 1 to 3 carbon atoms in the alkenyl chain, phenyl-alkyl-having 1-3 carbon atoms in the alkyl chain and wherein the phenyl moiety may be further substituted by an oxygen or a sulphur atom in any position, pyridyl-alkyl- having 1 to 2 carbon atoms in the alkyl chain, and trifluoromethyl, R 2 is selected from the group consisting of hydrogen and halogen, and R 3 is selected from the group consisting of hydrogen, halogen, and alkyl having 1 to 2 carbon atoms; comprising: in Step 1, reacting a compound of Formula (II) with a compound of Formula (III) under conditions sufficient to form a compound of Formula (IV): in Step 2, reacting a compound of Formula (V) under conditions sufficient to form a compound of Formula (VI): in Step 3, reacting a compound of Formula (VI) with a zinc reagent of Formula (XI) under conditions sufficient to form a compound of Formula (VII): in Step 4, reacting a compound of Formula (VII) under conditions sufficient to form a compound of Formula (VIII): in Step 5, reacting a compound of Formula (VIII) with a compound of Formula (IV) under conditions sufficient to form a compound of Formula (IX): in Step 6, reacting a compound of Formula (IX) under conditions sufficient to form a compound of Formula (X): in Step 7, reacting a compound of Formula (X) under conditions sufficient to form a compound of Formula (I): R 1 is selected from the group consisting of halogen, alkyl having 1 to 2 carbon atoms, phenylalkynyl- having 2 to 3 carbon atoms in the alkynyl chain, phenyl-alkenyl- having 1 to 3 carbon atoms in the alkenyl chain, phenyl-alkyl-having 1-3 carbon atoms in the alkyl chain and wherein the phenyl moiety may be further substituted by an oxygen or a sulphur atom in any position, pyridyl-alkyl- having 1 to 2 carbon atoms in the alkyl chain, and trifluoromethyl, R 2 is selected from the group consisting of hydrogen and halogen, and R 3 is selected from the group consisting of hydrogen, halogen, and alkyl having 1 to 2 carbon atoms; in Step 1, reacting a compound of Formula (II) with a compound of Formula (III) under conditions sufficient to form a compound of Formula (IV): in Step 2, reacting a compound of Formula (V) under conditions sufficient to form a compound of Formula (VI): in Step 3, reacting a compound of Formula (VI) with a zinc reagent of Formula (XI) under conditions sufficient to form a compound of Formula (VII): in Step 4, reacting a compound of Formula (VII) under conditions sufficient to form a compound of Formula (VIII): in Step 5, reacting a compound of Formula (VIII) with a compound of Formula (IV) under conditions sufficient to form a compound of Formula (IX): in Step 6, reacting a compound of Formula (IX) under conditions sufficient to form a compound of Formula (X): in Step 7, reacting a compound of Formula (X) under conditions sufficient to form a compound of Formula (I):
An air conditioner configured to condition air by connecting an indoor unit including a first heat exchanger , in which a refrigerant exchanging heat with room air flows, to an outdoor unit including a second heat exchanger in which a refrigerant exchanging heat with outdoor air flows, the first heat exchanger including a first heat transfer tube (11a1; 61a1; 81a1; 121a) made of aluminum or aluminum alloy, the second heat exchanger including a second heat transfer tube made of aluminum or aluminum alloy, a first sacrificial layer (45a; 75a; 95a; 132) being formed on an outer circumferential surface of the first heat transfer tube (11a1; 61a1; 81a1; 121a), a second sacrificial layer being formed on an outer circumferential surface of the second heat transfer tube , and characterized by the maximum thickness (to) of the second sacrificial layer being larger than the maximum thickness (ti1; ti3; ti5; ti8) of the first sacrificial layer (45a; 75a; 95a; 132). the first heat exchanger including a first heat transfer tube (11a1; 61a1; 81a1; 121a) made of aluminum or aluminum alloy, the second heat exchanger including a second heat transfer tube made of aluminum or aluminum alloy, a first sacrificial layer (45a; 75a; 95a; 132) being formed on an outer circumferential surface of the first heat transfer tube (11a1; 61a1; 81a1; 121a), a second sacrificial layer being formed on an outer circumferential surface of the second heat transfer tube , and characterized by the maximum thickness (to) of the second sacrificial layer being larger than the maximum thickness (ti1; ti3; ti5; ti8) of the first sacrificial layer (45a; 75a; 95a; 132).
An electrolyte composition comprising a compound of Formula I or Formula II: wherein R 1 , R 2 , and R 3 are the same or different and are independently selected from the group consisting of C 1 to C 6 linear or branched alkyl and fluorine, and wherein at least one of R 1 , R 2 , or R 3 is fluorine; "Spacer" is absent or is selected from the group consisting of C 2 alkylene, alkenylene, or alkynylene, provided that when "Spacer" is absent, Y is present; wherein each n is independently from 1 to 15, Y is absent or is wherein subscript "x" is an integer from 1 to 15; and each R 4 is the same or different and is selected from the group consisting of cyano (-CN), cyanate (-OCN), isocyanate (-NCO), thiocyanate (-SCN) and isothiocyanate (-NCS); in combination with a lithium-containing salt.
Composable machine tool comprising a kit for cylindrical and conical turning machining operations comprising an element which may be fixed on a workpiece , wherein a flange is rotatably mounted on the element , wherein the flange is connected, by means of at least three elongated elements of which an element is hollow, to a ring , wherein the element is fixed to a machine that generates the rotation motion of the flange and of the ring connected to said flange , characterized in that the hollow element is equipped with a worm screw and a scroll nut , that the rotation of the worm screw is actuated by a gearmotor fixed on the flange , that a tool head slidable in a guide is mounted on the scroll nut and that the ring is equipped with at least three stabilization elements that can be in contact with the surface of the work piece during machining of the workpiece .
A multilayer film comprising a multi-layer structure unit which is a 51-layered or more multiple layer formed by alternately layering a layer (A layer) a main component of which is a polyester resin (resin A) having a dicarboxylic component and a diol component, and a layer (B layer) a main component of which is a thermoplastic resin (resin B) different from the resin A in optical properties; wherein at least one surface of said multi-layer structure unit has a refractive index of 1.68 or more and 1.80 or less, wherein said surface has a critical load of 15 mN or less at 100°C in a scratch test measured using the method according to the description, and wherein said multilayer film has at least one reflection bandwidth having a reflectance of 30% or more continuous over a wavelength width of 20 nm or more in a profile of reflectance measured on at least one surface side of said multi-layer structure unit. wherein at least one surface of said multi-layer structure unit has a refractive index of 1.68 or more and 1.80 or less, wherein said surface has a critical load of 15 mN or less at 100°C in a scratch test measured using the method according to the description, and wherein said multilayer film has at least one reflection bandwidth having a reflectance of 30% or more continuous over a wavelength width of 20 nm or more in a profile of reflectance measured on at least one surface side of said multi-layer structure unit.
A device for use in measuring glucose in a host, the device comprising: a transcutaneous sensor operably connected to sensor electronics , the sensor electronics configured for measuring glucose in a host; at least one electrical contact configured to operably connect the sensor to the sensor electronics; a sealing member having a durometer hardness of from about 20 Shore A to about 50 Shore A, said sealing member at least partially surrounding at least one of the sensor and the electrical contact, wherein the sealing member is configured to seal the electrical contact from moisture when the sensor is operably connected to the sensor electronics; and, a housing on which the sealing member is disposed; wherein the sealing member is mechanically maintained on the housing by means of male-female mechanical structures so that there is no substantial translation, deformation and/or compression of the sealing member during insertion of the sensor into subcutaneous tissue of the host using an applicator. a transcutaneous sensor operably connected to sensor electronics , the sensor electronics configured for measuring glucose in a host; at least one electrical contact configured to operably connect the sensor to the sensor electronics; a sealing member having a durometer hardness of from about 20 Shore A to about 50 Shore A, said sealing member at least partially surrounding at least one of the sensor and the electrical contact, wherein the sealing member is configured to seal the electrical contact from moisture when the sensor is operably connected to the sensor electronics; and, a housing on which the sealing member is disposed; wherein the sealing member is mechanically maintained on the housing by means of male-female mechanical structures so that there is no substantial translation, deformation and/or compression of the sealing member during insertion of the sensor into subcutaneous tissue of the host using an applicator.
Component of a system for the drainage of rainwater in underpressure , characterised in that the component is provided with control means suitable to control the flow rate through a drainpipe of the system for the drainage of rainwater in underpressure , wherein the component itself comprises at least a part of a drainpipe or pipe piece , wherein the component optionally comprises a part of a roof drain , which roof drain comprises an air shutoff member , wherein the control means are integrated partially or entirely in said part of a drainpipe or pipe piece and/or partially or entirely in a part of said roof drain , whereby the control means are such that they allow the flow rate through said part of the drainpipe or pipe piece concerned to be increasingly reduced as and when an underpressure (ΔP) in said part of the drainpipe or pipe piece concerned becomes greater and/or as and when the flow speed in said part of the drainpipe or pipe piece increases and vice versa, and whereby the control means comprise at least one movable or deformable control element intended to come into direct contact during operation with the drained away rainwater and whereby a movement or deformation of the control element which determines its position is the direct consequence of this contact with the drained away rainwater .
Method of preparing a non-covalently cross-linked polymer system comprising the steps of: preparing a melt of a copolymer based on a first comonomer and at least one second comonomer, the first comonomer being selected from L-lactide and D-lactide; and adding a lactide-containing stereocomplex forming agent to the melt, wherein the stereocomplex forming agent is selected such that the resulting polymer system comprises a combination of constitution units derived from L-lactide and constitution units derived from D-lactide forming stereocomplexes. preparing a melt of a copolymer based on a first comonomer and at least one second comonomer, the first comonomer being selected from L-lactide and D-lactide; and adding a lactide-containing stereocomplex forming agent to the melt, wherein the stereocomplex forming agent is selected such that the resulting polymer system comprises a combination of constitution units derived from L-lactide and constitution units derived from D-lactide forming stereocomplexes.
Film comprising a linear low density polyethylene - having a density in the range from 915 kg/m 3 to at most 925 kg/m 3 as determined using ISO1872-2, - having a molecular weight distribution (M w /M n ) in the range from 2.5 to 3.5 - having an area under the peak in the temperature range from 20 to 40°C determined using an analytical temperature rising elution fractionation analysis using 1,2-dichlorobenzene and a heating rate of 1°C/min, wherein the area is in the range from 5 to 20% of the sum of the areas under all peaks determined with the analytical temperature rising elution fractionation analysis, wherein the amount of zirconium us in the range from 0.01 to 10ppm based on the linear low density polyethylene. - having a density in the range from 915 kg/m 3 to at most 925 kg/m 3 as determined using ISO1872-2, - having a molecular weight distribution (M w /M n ) in the range from 2.5 to 3.5 - having an area under the peak in the temperature range from 20 to 40°C determined using an analytical temperature rising elution fractionation analysis using 1,2-dichlorobenzene and a heating rate of 1°C/min, wherein the area is in the range from 5 to 20% of the sum of the areas under all peaks determined with the analytical temperature rising elution fractionation analysis,
A component mounting machine , comprising: a movable base which is movable within an XY plane with respect to a base ; a rotary head which is configured to be attachable to and detachable from a drive unit supported by the movable base , which holds a plurality of suction nozzles on a circumference, and which is rotatable around an axial line, wherein the rotary head is any among at least two types of rotary heads , such as a first rotary head in which four suction nozzles are respectively held to be rotatable on the circumference, and a second rotary head in which the suction nozzles of which the number is more than four are respectively held to be rotatable on a pitch circle diameter which is the same as that of the suction nozzle of the first rotary head ; a component camera having a viewing field (IA) which can image all of the components (PB) suctioned to the plurality of suction nozzles of the second rotary head at once within the viewing field (IA); and a control device in which an angular position of the first rotary head and an angular position of the components (PA) suctioned to the suction nozzles are respectively controlled to be changed by 45 degrees when the first rotary head is attached to the drive unit , so that the components (PA) held by the suction nozzles are in the viewing field (IA) of the component camera , so that the components (PA) held by the suction nozzles can be imaged by the component camera . a movable base which is movable within an XY plane with respect to a base ; a rotary head which is configured to be attachable to and detachable from a drive unit supported by the movable base , which holds a plurality of suction nozzles on a circumference, and which is rotatable around an axial line, wherein the rotary head is any among at least two types of rotary heads , such as a first rotary head in which four suction nozzles are respectively held to be rotatable on the circumference, and a second rotary head in which the suction nozzles of which the number is more than four are respectively held to be rotatable on a pitch circle diameter which is the same as that of the suction nozzle of the first rotary head ; a component camera having a viewing field (IA) which can image all of the components (PB) suctioned to the plurality of suction nozzles of the second rotary head at once within the viewing field (IA); and a control device in which an angular position of the first rotary head and an angular position of the components (PA) suctioned to the suction nozzles are respectively controlled to be changed by 45 degrees when the first rotary head is attached to the drive unit , so that the components (PA) held by the suction nozzles are in the viewing field (IA) of the component camera , so that the components (PA) held by the suction nozzles can be imaged by the component camera .