mhurhangee/patent-ind-claim-en huggingface dataset:
An assembly comprising a shaft extending along an axial direction and an element configured to be coupled to the shaft by shrink-fitting, the shaft and the element being intended to form a rotor of a turbomachine, the shaft and the element each including an axial shrink-fitting portion (P12, P12A, P12B, P12C, P14, P16, P18, P28, P30), the shaft comprising an inner cavity in the axial shrink-fitting portion (P12, P12A, P12B, P12C), an internal diameter (Di20, Di20A, Di20B, Di20C) of the inner cavity being greater than or equal to 50% of an external diameter (De12) of the axial shrink-fitting portion (P12, P12A, P12B, P12C) of the shaft , characterized in that a difference (H) between the external diameter (De12) of the axial shrink-fitting portion (P12, P12A, P12B, P12C) of the shaft and an internal diameter (Di16) of the axial shrink-fitting portion (P14, P16, P18, P28, P30) of the element is less than or equal to 50 μm when the element is not coupled to the shaft , the external diameter (De12) of the axial shrink-fitting portion (P12, P12A, P12B, P12C) of the shaft being greater than the internal diameter (Di16) of the axial shrink-fitting portion (P14, P16, P18, P28, P30) of the element .
Installation for casting under pressure with a permanent casting mould consisting of at least two casting mould parts, in particular of two casting mould halves, wherein at least one casting mould part can be pivoted, after opening the permanent casting mould, into a position in which the inner surface of this casting mould part can be handled, preferably by one person , in a work-facilitating and time-saving manner, characterized in that a rail system sunk in the floor or positioned on the floor is provided on which there is arranged at least one carriage for fully automatically receiving or removing and fully automatically delivering or transferring a furnace , wherein the carriage swings between a casting device of the counter-pressure or low-pressure die casting installation and a standby position situated remotely therefrom in such a way that the carriage receives a furnace at the standby position and transfers it into the casting device not yet provided with a furnace , or that the carriage removes a furnace from the casting device and delivers it to a free point of the standby position , in particular for reloading with melt, and the carriage is additionally provided for fully automatically receiving or removing and fully automatically delivering or transferring a casting mould or casting mould half, wherein the carriage swings between the casting device and a standby position situated remotely therefrom in such a way that the carriage receives a casting mould or casting mould half at the standby position and transfers it into the casting device not yet provided with a casting mould or casting mould half, or that the carriage receives a casting mould or casting mould half from the casting device and delivers it to a free point of the standby position for further use, in particular for intermediate storage or for exchange, wherein the carriage has at least two planes, wherein a lower plane is provided for fully automatically receiving or removing and fully automatically delivering or transferring the furnace , and an upper plane is provided for fully automatically receiving or removing and fully automatically delivering or transferring the casting mould or casting mould half.
A surgical tissue shaver comprising: a shaft extending from a proximal shaft end to a distal shaft end , the shaft comprising a tubular body defining a cannula extending from the proximal shaft end to the distal shaft end ; and a cutter head at the distal shaft end and extending along a longitudinal axis , the cutter head having a cutter opening in fluid communication with the cannula , wherein at least a portion of the cutter opening extending along the longitudinal axis is defined between a first row of teeth and a second row of teeth opposite the first row of teeth with respect to the longitudinal axis ; wherein a first tooth selected from the first row of teeth is defined by a respective proximal tooth surface and a respective distal tooth surface that intersect at a respective tooth edge , and wherein the respective tooth edge of the first tooth is oriented at a first angle of less than 90° relative to the longitudinal axis ; characterized in that a second tooth selected from the first row of teeth and the second row of teeth is defined by a respective proximal tooth surface and a respective distal tooth surface that intersect at a respective tooth edge , and wherein the respective tooth edge of the second tooth is oriented at a second angle relative to the longitudinal axis , the second angle being different from the first angle. a shaft extending from a proximal shaft end to a distal shaft end , the shaft comprising a tubular body defining a cannula extending from the proximal shaft end to the distal shaft end ; and a cutter head at the distal shaft end and extending along a longitudinal axis , the cutter head having a cutter opening in fluid communication with the cannula , wherein at least a portion of the cutter opening extending along the longitudinal axis is defined between a first row of teeth and a second row of teeth opposite the first row of teeth with respect to the longitudinal axis ; wherein a first tooth selected from the first row of teeth is defined by a respective proximal tooth surface and a respective distal tooth surface that intersect at a respective tooth edge , and wherein the respective tooth edge of the first tooth is oriented at a first angle of less than 90° relative to the longitudinal axis ; characterized in that a second tooth selected from the first row of teeth and the second row of teeth is defined by a respective proximal tooth surface and a respective distal tooth surface that intersect at a respective tooth edge , and wherein the respective tooth edge of the second tooth is oriented at a second angle relative to the longitudinal axis , the second angle being different from the first angle.
A composition comprising a complement inhibitor for use in a method of treatment of a chronic respiratory disorder, a chronic complement-mediated disorder that affects the musculoskeletal system, a chronic complement-mediated disorder characterized by the presence of autoantibodies and/or immune complexes in the body, and/or a chronic complement-mediated disorder that affects the nervous system in a subject in need thereof, by administering multiple doses of a complement inhibitor to the subject according to a dosing schedule in which successive doses are administered (i) at least 2 weeks after the plasma concentration of the complement inhibitor decreases to no more than 20% of the maximum plasma concentration that was reached after the previous dose; (ii) at least 2 weeks after plasma complement activation capacity has returned to at least 50% of baseline after the previous dose; or (iii) at intervals equal to at least 3 times the terminal plasma half-life of the complement inhibitor when administered by the same route, wherein the complement inhibitor is administered by the intravenous route and wherein the complement inhibitor (i) comprises an antibody that binds to C5 and inhibits cleavage of C5 or (ii) comprises a compstatin analog that inhibits cleavage of C3. (i) comprises an antibody that binds to C5 and inhibits cleavage of C5 or (ii) comprises a compstatin analog that inhibits cleavage of C3.
An aerial cable transportation system comprising: - at least one hauling cable ; - at least a first fixed structure ; - at least one transportation unit ; - a plurality of sensors configured for detecting the passage of the transportation units ; - at least one control unit ; wherein the plurality of sensors comprises at least a first sensor arranged at the exit area of the first fixed structure and at least a second sensor downstream of the first sensor , respectively, at at least one distance (s1, s2, sn) from the first sensor measured in cable-meters; the control unit is connected to the sensors and is configured for a) upon the passage of each transportation unit at the first sensor , starting to count the meters of cable fed outside the first fixed structure ; b) when the counting of the meters of cable fed outside the first fixed structure reaches amounts about equal to the at least one distance (s1, s2, sn) between the first and the at least second sensor, autonomously activating safety procedures if the passage of the transportation unit is not detected by each corresponding second sensor downstream of the first sensor . - at least one hauling cable ; - at least a first fixed structure ; - at least one transportation unit ; - a plurality of sensors configured for detecting the passage of the transportation units ; - at least one control unit ; a) upon the passage of each transportation unit at the first sensor , starting to count the meters of cable fed outside the first fixed structure ; b) when the counting of the meters of cable fed outside the first fixed structure reaches amounts about equal to the at least one distance (s1, s2, sn) between the first and the at least second sensor, autonomously activating safety procedures if the passage of the transportation unit is not detected by each corresponding second sensor downstream of the first sensor .
A replaceable head cutting tool in which a cylindrical mounting unit of a coupling member , which is made of a metal material having hardness lower than the hardness of a hard material of a tool body , is inserted into a mounting hole , which is formed in the tool body made of the hard material and includes a concave portion formed on an inner peripheral surface thereof, the mounting unit being plastically deformed so as to increase in diameter, and an outer peripheral surface of the mounting unit coming into close contact with the inner peripheral surface of the mounting hole and engaging with the concave portion , so that the tool body and the coupling member are joined to each other, wherein the concave portion includes a first wall surface that is inclined toward an outer peripheral side as the first wall surface moves in an insertion direction (F) in which the mounting unit is inserted into the mounting hole , and a second wall surface that is opposite to the first wall surface and is inclined toward an inner peripheral side as the second wall surface moves in the insertion direction (F), wherein on the tool body from a front end side towards a rear end side, a cutting edge portion on which cutting edges are formed, the engagement portion with which a wrench or the like can be engaged at the time of the replacement of the cutting head, and a tapered shaft portion are formed in this order; wherein an outer diameter of the tapered shaft portion is smaller than that of the cutting edge portion , and is also smaller than that of the engagement portion , and decreases gradually toward a rear end side; and wherein the mounting hole is opened in the rear end face of the tapered shaft portion characterized in that a plurality of the concave portions are formed, with intervals between each other, from a rear end face of the tool body toward the bottom of the mounting hole ; one or more of the concave portions close to the front end portion among the concave portions are formed in a portion corresponding to an engagement portion of the tool body in the direction of a center line (O) of the mounting hole ; a first inclination angle (α), which is formed between the first wall surface and a plane (S) perpendicular to the center line (O) of the mounting hole at a position where the first wall surface intersects with the inner peripheral surface of the mounting hole , is smaller than a second inclination angle (β), which is formed between the second wall surface and a plane (S) perpendicular to the center line (O) at a position where the second wall surface intersects with the inner peripheral surface of the mounting hole .
A system comprising: a network topology comprising a plurality of spine nodes (S1, S2), and a plurality of leaf nodes (L1, L2, L3), wherein a link between a first spine node (S2) and a first leaf node (L1) is inactive; the first spine node (S2) comprising one or more processors configured to: receive a packet to be transmitted to the first leaf node (L1); identify an alternative spine node (S1) at a same level in the network topology as the first spine node; and characterized by the one or more processors being further configured to: attach a tunnel label to the packet , wherein the tunnel label indicates the packet should be transmitted to the alternative spine node, the label comprises a route pointing to the alternative spine node and further indicates that the route is not a best path for reaching the first leaf node. a network topology comprising a plurality of spine nodes (S1, S2), and a plurality of leaf nodes (L1, L2, L3), wherein a link between a first spine node (S2) and a first leaf node (L1) is inactive; the first spine node (S2) comprising one or more processors configured to: receive a packet to be transmitted to the first leaf node (L1); identify an alternative spine node (S1) at a same level in the network topology as the first spine node; and characterized by the one or more processors being further configured to: attach a tunnel label to the packet , wherein the tunnel label indicates the packet should be transmitted to the alternative spine node, the label comprises a route pointing to the alternative spine node and further indicates that the route is not a best path for reaching the first leaf node. receive a packet to be transmitted to the first leaf node (L1); identify an alternative spine node (S1) at a same level in the network topology as the first spine node; and characterized by the one or more processors being further configured to: attach a tunnel label to the packet , wherein the tunnel label indicates the packet should be transmitted to the alternative spine node, the label comprises a route pointing to the alternative spine node and further indicates that the route is not a best path for reaching the first leaf node.
An air negative ion generating apparatus for generating air negative ions by bumping high-pressure gas flow carrying water molecules against a collision surface, the air negative ion generating apparatus comprising: a liquid container ; a high-pressure gas inlet pipe ; a core assembly having a liquid flow chamber and a liquid flow inlet ; the liquid flow inlet is in fluid communication with the liquid flow chamber , and a lower port of the liquid flow chamber is fixedly connected with a liquid conduit extending downwards; characterised in that the apparatus further comprises a cover body snapped onto a top opening end of the liquid container , and a water gas collision cabin provided inside the cover body ; wherein the core assembly is located inside the water gas collision cabin and the water gas collision cabin includes a cabin body having an open lower end, the water gas collision cabin being in fluid communication via the open lower end with an interior space of the cover body that is exterior to the water gas collision cabin ; wherein the cover body is provided with the high-pressure gas inlet pipe , the high-pressure gas inlet pipe being fixedly connected with the cover body and a lower end of the high-pressure gas inlet pipe extends into the water gas collision cabin ; wherein the core assembly further having a collision component , a lower port of the high-pressure gas inlet pipe being above and faces the collision component , and the liquid flow inlet being located between the lower port of the high-pressure gas inlet pipe and the collision component .
An immunoassay method of carrying out an antigen-antibody reaction under suppression of interference reaction of a rheumatoid factor using an immunoassay reagent in the presence of a sulfite, wherein the immunoassay reagent comprises a sulfite and a reducing substance.
A controlled release oral dosage form comprising: (i) a compound of formula (I): or a pharmaceutically acceptable polymorph, solvate or hydrate thereof; (ii) a swelling excipient; (iii) a cationic polymer in acidic pH; (iv) an anionic polymer in acidic pH; and wherein the swelling excipient is selected from the group consisting of hydroxyethylcellulose, polyethylene oxide, sodium carboxymethyl cellulose, hydroxypropyl cellulose, hydroxylpropyl methyl cellulose, methyl celluloses, croscarmellose sodium, sodium starch glycolate, wherein the cationic polymer in acidic pH is selected from the group consisting of chitosan, methacrylic acid-methyl methacrylate copolymer (1:1), methacrylic acid-methyl methacrylate copolymer (1:2), poly(butyl methacylate-co-2-dimethylaminoethyl methacrylate-co-methyl methacrylate) (1:2:1), and crosslinked acrylic acid copolymers, and wherein the anionic polymer in acidic pH is selected from the group consisting of an alginate, sodium carboxymethyl cellulose, chondroitin sulfate, carrageenan, glycosaminoglycans, mucopolysaccharides, pectin, gelatin and hyaluronic acid. (i) a compound of formula (I): or a pharmaceutically acceptable polymorph, solvate or hydrate thereof; (ii) a swelling excipient; (iii) a cationic polymer in acidic pH; (iv) an anionic polymer in acidic pH; and wherein the swelling excipient is selected from the group consisting of hydroxyethylcellulose, polyethylene oxide, sodium carboxymethyl cellulose, hydroxypropyl cellulose, hydroxylpropyl methyl cellulose, methyl celluloses, croscarmellose sodium, sodium starch glycolate, wherein the cationic polymer in acidic pH is selected from the group consisting of chitosan, methacrylic acid-methyl methacrylate copolymer (1:1), methacrylic acid-methyl methacrylate copolymer (1:2), poly(butyl methacylate-co-2-dimethylaminoethyl methacrylate-co-methyl methacrylate) (1:2:1), and crosslinked acrylic acid copolymers, and wherein the anionic polymer in acidic pH is selected from the group consisting of an alginate, sodium carboxymethyl cellulose, chondroitin sulfate, carrageenan, glycosaminoglycans, mucopolysaccharides, pectin, gelatin and hyaluronic acid.
A method of identifying or profiling a target cellular kinase that phosphorylates a selected substrate, comprising: a) providing a plurality of test protein preparations comprising the target cellular kinase and at least one phosphatase inhibitor; b) incubating each test protein preparation with the selected substrate and a kinase inhibitor, wherein the kinase inhibitor is different for each test protein preparation; c) determining whether the selected substrate is phosphorylated in each of the test protein preparations of b), thereby obtaining an inhibition profile for the target cellular kinase; and d) comparing the target cellular kinase inhibition profile with the inhibition profiles of known kinases, wherein the most similar known kinase inhibition profile(s) identify or profile the target cellular kinase. a) providing a plurality of test protein preparations comprising the target cellular kinase and at least one phosphatase inhibitor; b) incubating each test protein preparation with the selected substrate and a kinase inhibitor, wherein the kinase inhibitor is different for each test protein preparation; c) determining whether the selected substrate is phosphorylated in each of the test protein preparations of b), thereby obtaining an inhibition profile for the target cellular kinase; and d) comparing the target cellular kinase inhibition profile with the inhibition profiles of known kinases, wherein the most similar known kinase inhibition profile(s) identify or profile the target cellular kinase.
System of a tank for storing a food or beverage powder and a powder refilling container for refilling said tank with powder, in which : - the tank comprises a storing chamber and a powder inlet , - the powder refilling container comprises a powder outlet , the powder outlet of the powder refilling container and the powder inlet of the tank being designed for cooperating together in order to create a connection and a path for powder between the powder outlet of the powder refilling container and the powder inlet of the tank, and characterized in that the connection between the powder outlet of the powder refilling container and the powder inlet of the tank is designed so that, once the powder inlet and the powder outlet are connected, the connection enables the positioning of the powder outlet of the powder refilling container: - in one first position wherein the powder outlet of the powder refilling container is oriented upwardly, - in one second position wherein the powder outlet of the powder refilling container is oriented downwardly. - the tank comprises a storing chamber and a powder inlet , - the powder refilling container comprises a powder outlet , - in one first position wherein the powder outlet of the powder refilling container is oriented upwardly, - in one second position wherein the powder outlet of the powder refilling container is oriented downwardly.
A curable resin composition, comprising: (A) a vinyl sulfide compound represented by the following general formula ; and (B) an isocyanate compound having an isocyanate group: in formula , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , and R 16 may be the same or different from one another, and represent a hydrogen atom, a halogen atom, or an alkyl group having 1 to 6 carbon atoms, and n represents an integer of 0 to 10. (A) a vinyl sulfide compound represented by the following general formula ; and (B) an isocyanate compound having an isocyanate group: in formula , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , R 14 , R 15 , and R 16 may be the same or different from one another, and represent a hydrogen atom, a halogen atom, or an alkyl group having 1 to 6 carbon atoms, and n represents an integer of 0 to 10.
A closing cap which is configured to seal a reagent bottle , wherein the closing cap comprises a recess with an opening, a bottom and a collar surrounding the opening of the recess , and a body extending between the bottom and the collar , wherein at least part of the body is made of flexible material that allows deformation of at least the body when the recess is set at a pressure below ambient, so that a first sealing surface formed by the outer surface of the cap is moved inwards and the seal between the neck of a bottle or other vessel is released characterized in that - the outer surface of said body has a barrel shape, and - the inner surface of said cap body includes a relief . - the outer surface of said body has a barrel shape, and - the inner surface of said cap body includes a relief .