mhurhangee/patent-ind-claim-en huggingface dataset:
A method for targeted modification of a genomic locus of interest in a pluripotent rat cell, comprising: (a) introducing into the pluripotent rat cell a large targeting vector (LTVEC) comprising an insert nucleic acid flanked by a 5' homology arm complementary to a first nucleic acid sequence at the genomic locus of interest and a 3' homology arm complementary to a second nucleic acid sequence at the genomic locus of interest, wherein the 5' homology arm is at least 5 kb and the 3' homology arm is at least 5 kb; and (b) identifying a genetically modified pluripotent rat cell comprising a targeted genetic modification at the genomic locus of interest, wherein the targeted genetic modification is capable of being transmitted through the germline, and wherein the pluripotent rat cell to be used for targeted modification of the genomic locus of interest is obtainable by culturing isolated rat embryonic stem cells on a feeder cell layer that is not modified to express leukemia inhibitory factor (LIF) with a medium comprising about 50 U/mL to about 150 U/mL LIF and a combination of inhibitors consisting of a MEK pathway inhibitor and a GSK3 inhibitor. (a) introducing into the pluripotent rat cell a large targeting vector (LTVEC) comprising an insert nucleic acid flanked by a 5' homology arm complementary to a first nucleic acid sequence at the genomic locus of interest and a 3' homology arm complementary to a second nucleic acid sequence at the genomic locus of interest, wherein the 5' homology arm is at least 5 kb and the 3' homology arm is at least 5 kb; and (b) identifying a genetically modified pluripotent rat cell comprising a targeted genetic modification at the genomic locus of interest, wherein the targeted genetic modification is capable of being transmitted through the germline, and wherein the pluripotent rat cell to be used for targeted modification of the genomic locus of interest is obtainable by culturing isolated rat embryonic stem cells on a feeder cell layer that is not modified to express leukemia inhibitory factor (LIF) with a medium comprising about 50 U/mL to about 150 U/mL LIF and a combination of inhibitors consisting of a MEK pathway inhibitor and a GSK3 inhibitor. wherein the targeted genetic modification is capable of being transmitted through the germline, and wherein the pluripotent rat cell to be used for targeted modification of the genomic locus of interest is obtainable by culturing isolated rat embryonic stem cells on a feeder cell layer that is not modified to express leukemia inhibitory factor (LIF) with a medium comprising about 50 U/mL to about 150 U/mL LIF and a combination of inhibitors consisting of a MEK pathway inhibitor and a GSK3 inhibitor.
A centrifugal pump comprising: at least two diffusers comprising a first diffuser and a second diffuser, the first diffuser axially adjacent the second diffuser; each of the first diffuser and the second diffuser comprising: a first axial end comprising a plurality of male register tabs circumferentially dispersed around the first end ; and a second axial end comprising a plurality of female register slots circumferentially dispersed around the second end ; a coupling ring extending circumferentially between the first diffuser and the second diffuser, the coupling ring comprising a plurality of radial projections , each projection of the plurality of projections mated: around one of the male register tabs of the first diffuser; and inside one of the female register slots of the second diffuser. at least two diffusers comprising a first diffuser and a second diffuser, the first diffuser axially adjacent the second diffuser; each of the first diffuser and the second diffuser comprising: a first axial end comprising a plurality of male register tabs circumferentially dispersed around the first end ; and a second axial end comprising a plurality of female register slots circumferentially dispersed around the second end ; a first axial end comprising a plurality of male register tabs circumferentially dispersed around the first end ; and a second axial end comprising a plurality of female register slots circumferentially dispersed around the second end ; a coupling ring extending circumferentially between the first diffuser and the second diffuser, the coupling ring comprising a plurality of radial projections , each projection of the plurality of projections mated: around one of the male register tabs of the first diffuser; and inside one of the female register slots of the second diffuser. around one of the male register tabs of the first diffuser; and inside one of the female register slots of the second diffuser.
Flushing system for an intelligent toilet, comprising a water inlet valve and a cistern , wherein the water inlet valve is a water inlet valve with an air gap separation function and blocks the water inlet path when the liquid level of the cistern rises to a high water level setting, and opens the water inlet path when the liquid level of the cistern drops to a low water level setting, wherein provided between the water outlet path of the water inlet valve and the liquid level rising to the high water level setting is an air gap, wherein furthermore provided is a water pump , wherein a water outlet opening of the cistern is connected to a water inlet opening of the water pump by a water line , and wherein the water outlet opening of the water pump is connected to a flushing water duct of a ceramic body by a water line , wherein provided on the upper side of the cistern is an assembly opening, characterized in that the water inlet valve is assembled through the assembly opening on an upper portion of the cistern , and in that the water line , which is connected to the flushing water duct , by way of its end is connected to an inner end of a connector by a push-fit, wherein the outer end of the connector penetrates an assembly opening of the ceramic body and protrudes into the flushing water duct , wherein formed on the outer end of the connector is a detent which is enlarged towards the outside, wherein the connector is encompassed by a rubber part which is guided through the assembly opening on the ceramic body , wherein provided on the external side of the connector are a thread and a threaded nut for a rotational connection, and wherein the threaded nut interacts with the detent in such a manner that, when tightening the threaded nut , the rubber part is compressed from the outside and the inside in such a manner that said rubber part expands and is jammed in a sealing manner in the assembly opening .
Earth drilling device having a percussion piston for drilling in the ground which has at least one housing portion for the percussion piston , wherein an insert is arranged in the housing between the drill head tip and the percussion piston in such a manner that said insert transmits at least part of the energy of the percussion piston to said housing , characterized in that the insert is held in the housing by means of a shrink-fit adhesive connection.
A filter holding device (1; 41; 75; 81) arranged for providing at least one filter (7; 43a, 43b; 85) inside a flexible bag (3; 71), said filter holding device comprising attaching means (19a-d, 21a-d; 79; 83) for attaching the filter holding device to an inner surface of the flexible bag, with a distancing means (31; 47a, 47b) provided on at least one side of the filter holding device to which side the at least one filter (7; 43a, 43b; 85) should be attached and arranged to provide the at least one filter held by the filter holding device at a distance from the inner surface of the flexible bag, wherein said filter holding device further comprises at least two flow deflector areas (23a, 23b; 53a, 53b) provided on opposite ends of the filter holding device, said flow deflector areas being angled in relation to the rest of the filter holding device such that they are pointing away from the surface of the flexible bag to which the filter holding device is attached when the filter holding device (1; 41; 75; 81) is provided in a flexible bag (3; 71).
A detergent composition for hard water scale control comprising: at least 50 wt-% of alkali metal hydroxide; and at least one copolymer (A) comprising the following monomers in copolymerized form: from 30 to 95% by weight of at least one monoethylenically unsaturated C 3 -C 8 -carboxylic acid, or an anhydride or salt thereof, and from 5 to 70% by weight of at least one nonionic monomer of the formula I H 2 C=C(R 1 )(CH 2 ) x O[R 2 -O] y -R 3 (I) in which R 1 is hydrogen or methyl, R 2 are identical or different, linear or branched C 2 -C 6 -alkylene wherein R 2 -O may be arranged in blocks or randomly, and R 3 is hydrogen or a straight-chain or branched C 1 -C 4 -alkyl, x is 0, 1 or 2 and y is a number from 3 to 50; wherein the detergent composition is free of phosphate, the copolymer (A) having a K value of 15 to 30 measured at pH 7 in 1% by weight aqueous solution at 25°C according to the specification. at least 50 wt-% of alkali metal hydroxide; and at least one copolymer (A) comprising the following monomers in copolymerized form: from 30 to 95% by weight of at least one monoethylenically unsaturated C 3 -C 8 -carboxylic acid, or an anhydride or salt thereof, and from 5 to 70% by weight of at least one nonionic monomer of the formula I H 2 C=C(R 1 )(CH 2 ) x O[R 2 -O] y -R 3 (I) in which R 1 is hydrogen or methyl, R 2 are identical or different, linear or branched C 2 -C 6 -alkylene wherein R 2 -O may be arranged in blocks or randomly, and R 3 is hydrogen or a straight-chain or branched C 1 -C 4 -alkyl, x is 0, 1 or 2 and y is a number from 3 to 50; from 30 to 95% by weight of at least one monoethylenically unsaturated C 3 -C 8 -carboxylic acid, or an anhydride or salt thereof, and from 5 to 70% by weight of at least one nonionic monomer of the formula I H 2 C=C(R 1 )(CH 2 ) x O[R 2 -O] y -R 3 (I) in which R 1 is hydrogen or methyl, R 2 are identical or different, linear or branched C 2 -C 6 -alkylene wherein R 2 -O may be arranged in blocks or randomly, and R 3 is hydrogen or a straight-chain or branched C 1 -C 4 -alkyl, x is 0, 1 or 2 and y is a number from 3 to 50; wherein the detergent composition is free of phosphate, the copolymer (A) having a K value of 15 to 30 measured at pH 7 in 1% by weight aqueous solution at 25°C according to the specification.
A blower comprising: a fan which is rotated about a rotation axis (C); and a plurality of stationary blades which are installed to be a radial shape about the rotation axis (C) in a direction in which the airflow generated by the rotation of the fan is discharged, and are curved in a direction opposite to the rotation direction of the fan as they extend from an inner circumferential portion to an outer circumferential portion, wherein the plurality of stationary blades each comprise an inlet edge through which the airflow generated by the fan is introduced; and an outlet edge through which the airflow introduced into the inlet edge is discharged, wherein an inlet angle (θ1) is formed between the rotation axis (C) and a virtual straight line (T1) extending at a tangent, at the inlet edge , from a curved virtual centre line (L1) passing through the centre of the thickness of the stationary blade from the inlet edge to the outlet edge in a cross-section of the stationary blade , and a chord angle (θ3) is formed between a chord (S) and the rotation axis (C), the chord (S) representing a virtual straight line connecting the inlet edge and the outlet edge in said cross-section of the stationary blade , characterised in that the inlet angle (θ1) and the chord angle (θ3) are larger at the inner circumferential portion and the outer circumferential portion than at a central portion between the inner circumferential portion and the outer circumferential portion. a fan which is rotated about a rotation axis (C); and a plurality of stationary blades which are installed to be a radial shape about the rotation axis (C) in a direction in which the airflow generated by the rotation of the fan is discharged, and are curved in a direction opposite to the rotation direction of the fan as they extend from an inner circumferential portion to an outer circumferential portion, wherein the plurality of stationary blades each comprise an inlet edge through which the airflow generated by the fan is introduced; and an outlet edge through which the airflow introduced into the inlet edge is discharged, wherein an inlet angle (θ1) is formed between the rotation axis (C) and a virtual straight line (T1) extending at a tangent, at the inlet edge , from a curved virtual centre line (L1) passing through the centre of the thickness of the stationary blade from the inlet edge to the outlet edge in a cross-section of the stationary blade , and a chord angle (θ3) is formed between a chord (S) and the rotation axis (C), the chord (S) representing a virtual straight line connecting the inlet edge and the outlet edge in said cross-section of the stationary blade , characterised in that the inlet angle (θ1) and the chord angle (θ3) are larger at the inner circumferential portion and the outer circumferential portion than at a central portion between the inner circumferential portion and the outer circumferential portion.
A resource mapping method, wherein the method comprises: generating (S101), by a network device, control information, wherein the network device communicates with a terminal device using a downlink transmission resource, wherein the downlink transmission resource is divided into a control region assigned to control channels and a data region assigned to data channels, wherein the control information is used to indicate the following information: at least one bandwidth region in which at least one frequency domain resource unit is located, wherein the at least one frequency domain resource unit is a scheduling unit of a frequency domain resource, is in the control region of the downlink transmission resource, and is used when the network device and a terminal device transmit a data channel, and wherein an operating bandwidth of the terminal device comprises a plurality of evenly spaced bandwidth regions, and the at least one bandwidth region is one or more of the plurality of bandwidth regions, a granularity of the at least one frequency domain resource unit, wherein the granularity of the at least one frequency domain resource unit is corresponding to a granularity of a resource unit used, when the network device and the terminal device transmit a control channel in the control region of the downlink transmission resource, and a location of the at least one frequency domain resource unit in the bandwidth region; and sending (S102), by the network device, the control information to the terminal device, whereby the data channel reuses an idle frequency domain resource in the control region of the downlink transmission resource for data transmission. at least one bandwidth region in which at least one frequency domain resource unit is located, wherein the at least one frequency domain resource unit is a scheduling unit of a frequency domain resource, is in the control region of the downlink transmission resource, and is used when the network device and a terminal device transmit a data channel, and wherein an operating bandwidth of the terminal device comprises a plurality of evenly spaced bandwidth regions, and the at least one bandwidth region is one or more of the plurality of bandwidth regions, a granularity of the at least one frequency domain resource unit, wherein the granularity of the at least one frequency domain resource unit is corresponding to a granularity of a resource unit used, when the network device and the terminal device transmit a control channel in the control region of the downlink transmission resource, and a location of the at least one frequency domain resource unit in the bandwidth region; and sending (S102), by the network device, the control information to the terminal device, whereby the data channel reuses an idle frequency domain resource in the control region of the downlink transmission resource for data transmission.
A double-layered director, configured to be arranged directly above a corresponding high-frequency radiation unit, the double-layered director includes a first director and a second director installed above the first director , wherein the second director includes a dielectric substrate and a split copper foil installed on the dielectric substrate ; the split copper foil includes a plurality of small copper foils , and the plurality of small copper foils are circumferentially arranged at intervals around a center of the second director ; the small copper foils are of an annular sectoral shape; wherein the double-layered director is configured to weaken the influence of the resonant current of the director on the high-frequency radiation unit due to arrangement of the split copper on the electric substrate; and the first director is made of a whole piece of a metal sheet. the double-layered director includes a first director and a second director installed above the first director , wherein the second director includes a dielectric substrate and a split copper foil installed on the dielectric substrate ; the split copper foil includes a plurality of small copper foils , and the plurality of small copper foils are circumferentially arranged at intervals around a center of the second director ; the small copper foils are of an annular sectoral shape; wherein the double-layered director is configured to weaken the influence of the resonant current of the director on the high-frequency radiation unit due to arrangement of the split copper on the electric substrate; and the first director is made of a whole piece of a metal sheet.
A method at a network node in a wireless communication network , of selecting an interference-mitigation, IM, mode, to be used by a wireless device operating in the network , said method comprising: obtaining capability information for a wireless device , wherein the capability information indicates which particular IM modes the wireless device supports from among a plurality of defined IM modes that differ with respect to an amount of network assistance required; obtaining selection information bearing on the selection of IM modes for the wireless device , said selection information comprising one or more operating parameters associated with current operation of the network and/or the wireless device ; selecting one or more of the supported IM modes from the particular IM modes, as indicated by the capability information, based on evaluating the selection information; and sending IM configuration information for the wireless device , indicating the selected one or more IM modes. obtaining capability information for a wireless device , wherein the capability information indicates which particular IM modes the wireless device supports from among a plurality of defined IM modes that differ with respect to an amount of network assistance required; obtaining selection information bearing on the selection of IM modes for the wireless device , said selection information comprising one or more operating parameters associated with current operation of the network and/or the wireless device ; selecting one or more of the supported IM modes from the particular IM modes, as indicated by the capability information, based on evaluating the selection information; and sending IM configuration information for the wireless device , indicating the selected one or more IM modes.
Self-lubricating composite friction part being able to be subjected in operation to temperatures at least equal to 250°C, comprising, along the friction surface, a single layer of a fabric formed by weft and warp strands of polytetrafluoroethylene, this fabric being impregnated with a heat-stable resin having a glass transition temperature at least equal to 250°C, characterized in that the single layer is formed by the winding on a mandrel of a strip of fabric in a helical manner such that the strip comes edge-to-edge with itself after each turn.
Metering device for the metered introduction of a pourable cleaning agent into a treatment chamber of a program-controlled cleaning device, in particular a dishwasher, comprising a reservoir , intended to accommodate the cleaning agent, and a motor-rotatably mounted support unit , which receives the reservoir in an exchangeable manner, the reservoir having a storage chamber and a metering chamber , which opens into a metering opening , the metering chamber being fluidically connected to the storage chamber with the interposition of a passage opening , characterised by a closure means , by means of which the passage opening is closed at least until the reservoir is used for the first time as intended, the closure means having a closure element, which is movably arranged on the reservoir and can be transferred from a closed position to an open position and vice versa, and which is a wall portion that corresponds to the passage opening and is rotatably mounted on a turntable . characterised by a closure means , by means of which the passage opening is closed at least until the reservoir is used for the first time as intended, the closure means having a closure element, which is movably arranged on the reservoir and can be transferred from a closed position to an open position and vice versa, and which is a wall portion that corresponds to the passage opening and is rotatably mounted on a turntable .
Vacuum cleaner nozzle (N) having left and right side openings (O) that are alternatingly open when the vacuum cleaner nozzle (N) is moved along a floor.
A system comprising: at least one computing device configured to model deformation in a set of manufactured components by performing actions including: forming a pre-exposure statistical distribution of measured coordinates describing the set of manufactured components from a pre-exposure three-dimensional depiction of a first sample of the manufactured component , and forming a post-exposure statistical distribution of measured coordinates describing the set of manufactured components from a post-exposure three-dimensional depiction of a second sample of the manufactured component ; calculating a difference between parameters of the pre-exposure statistical distribution and the post-exposure statistical distribution ; and adjusting an expected deformation model for the set of manufactured components based upon the difference between the parameters of the pre-exposure statistical distribution and the post-exposure statistical distribution , to model the deformation of the manufactured component . forming a pre-exposure statistical distribution of measured coordinates describing the set of manufactured components from a pre-exposure three-dimensional depiction of a first sample of the manufactured component , and forming a post-exposure statistical distribution of measured coordinates describing the set of manufactured components from a post-exposure three-dimensional depiction of a second sample of the manufactured component ; calculating a difference between parameters of the pre-exposure statistical distribution and the post-exposure statistical distribution ; and adjusting an expected deformation model for the set of manufactured components based upon the difference between the parameters of the pre-exposure statistical distribution and the post-exposure statistical distribution , to model the deformation of the manufactured component .