mhurhangee/patent-ind-claim-en huggingface dataset:
A pharmaceutical composition for use in treating or ameliorating the effects of a cancer in a subject, the pharmaceutical composition comprising a pharmaceutically acceptable diluent or carrier and an effective amount of (i) a first anti-cancer agent, which is BVD-523 or a pharmaceutically acceptable salt thereof, (ii) a second anti-cancer agent, which is (ii-1) selected from the group consisting of trametinib (Japan Tobacco), MEK162, pharmaceutically acceptable salts thereof, and combinations thereof; or (ii-2) GDC-0623 (Hoffmann-La Roche) or a pharmaceutically acceptable salt thereof, and (iii) at least one additional therapeutic agent selected from the group consisting of an antibody or fragment thereof, a toxin, a radionuclide, an immunomodulator, a radiosensitizing agent, a hormone, an anti-angiogenesis agent, and combinations thereof. (i) a first anti-cancer agent, which is BVD-523 or a pharmaceutically acceptable salt thereof, (ii) a second anti-cancer agent, which is (ii-1) selected from the group consisting of trametinib (Japan Tobacco), MEK162, pharmaceutically acceptable salts thereof, and combinations thereof; or (ii-2) GDC-0623 (Hoffmann-La Roche) or a pharmaceutically acceptable salt thereof, and (ii-1) selected from the group consisting of trametinib (Japan Tobacco), MEK162, pharmaceutically acceptable salts thereof, and combinations thereof; or (ii-2) GDC-0623 (Hoffmann-La Roche) or a pharmaceutically acceptable salt thereof, and (iii) at least one additional therapeutic agent selected from the group consisting of an antibody or fragment thereof, a toxin, a radionuclide, an immunomodulator, a radiosensitizing agent, a hormone, an anti-angiogenesis agent, and combinations thereof.
A plastomer spring for use in a fluid pump, the spring comprising a first end portion and a second end portion and one or more spring sections therebetween, connecting the first end portion to the second end portion and compressible in an axial direction of the spring from an initial condition to a compressed condition, wherein the first end portion defines a valve chamber for captively receiving a moveable valve element , the valve chamber including a valve seat against which the valve element may seal to prevent fluid flow through the valve chamber and a valve support element , characterised in that the valve chamber further comprises a lid , arranged to allow positioning of the valve element within the valve chamber during a fabrication process.
Sensor for detecting a physical measurement variable using a transmitter field , comprising: - a sensor circuit for detecting the transmitter field and for outputting a sensor signal that is dependent on the physical measurement variable, - a housing that houses the sensor circuit , and - a moisture measurement pickup between the sensor circuit and the housing , which moisture measurement pickup is configured to generate a monitoring signal , which is dependent on moisture ingressing between the sensor circuit and the housing , wherein the sensor circuit comprises a measurement pickup for converting the transmitter field to a transmitter signal and a signal processing circuit for outputting the sensor signal based on the transmitter signal, and wherein the moisture measurement pickup is arranged on a surface of the measurement pickup and/or the signal processing circuit . - a sensor circuit for detecting the transmitter field and for outputting a sensor signal that is dependent on the physical measurement variable, - a housing that houses the sensor circuit , and - a moisture measurement pickup between the sensor circuit and the housing , which moisture measurement pickup is configured to generate a monitoring signal , which is dependent on moisture ingressing between the sensor circuit and the housing , wherein the sensor circuit comprises a measurement pickup for converting the transmitter field to a transmitter signal and a signal processing circuit for outputting the sensor signal based on the transmitter signal, and wherein the moisture measurement pickup is arranged on a surface of the measurement pickup and/or the signal processing circuit .
Electronic unit for a hand-held machine tool, with a mounting frame comprising a receiving space into which a printed circuit board carrying a plurality of electronic components is inserted, and with at least one heat sink for the dissipation of heat loss occurring at the electronic components , characterized in that a shaft section , with at least one insertion shaft oriented perpendicularly to the printed circuit board , is formed on the mounting frame for receiving an electronic component along an insertion direction pointing away from the printed circuit board , wherein the shape and the height of the at least one insertion shaft is adapted to the electronic component received therein, and in that the at least one heat sink is assigned to the shaft section .
A lithium ion battery electrolyte, comprising a non-aqueous organic solvent, a lithium salt, and additives, wherein the additives comprise additive A cyclophosphazene compound, additive B lithium fluorophosphate compound, and additive C selected from at least one of silane phosphate compound, silane phosphite compound and silane borate compound.
A wine press comprising: - a vat with a grape pressing chamber , - at least one must collection chamber communicating with the pressing chamber by way of at least one grille , - at least one must discharge stub communicating with the must collection chamber, - at least one cleaning stub configured for introduction into the must collection chamber of a cleaning ferret, comprising: - at least one slender apertured ferret guide conduit associated with the cleaning stub , wherein: - the ferret guide conduit extends in the must collection chamber, - the ferret guide conduit is more confined than the must collection chamber, characterised in that - the ferret guide conduit comprises a plurality of aligned studs disposed in the must collection chamber between the wall of the vat and the grille , the studs supporting the grille and delimiting the ferret guide conduit. - a vat with a grape pressing chamber , - at least one must collection chamber communicating with the pressing chamber by way of at least one grille , - at least one must discharge stub communicating with the must collection chamber, - at least one cleaning stub configured for introduction into the must collection chamber of a cleaning ferret, comprising: - at least one slender apertured ferret guide conduit associated with the cleaning stub , wherein: - the ferret guide conduit extends in the must collection chamber, - the ferret guide conduit is more confined than the must collection chamber, characterised in that - the ferret guide conduit comprises a plurality of aligned studs disposed in the must collection chamber between the wall of the vat and the grille , the studs supporting the grille and delimiting the ferret guide conduit. - at least one slender apertured ferret guide conduit associated with the cleaning stub , wherein: - the ferret guide conduit extends in the must collection chamber, - the ferret guide conduit is more confined than the must collection chamber, characterised in that - the ferret guide conduit comprises a plurality of aligned studs disposed in the must collection chamber between the wall of the vat and the grille , the studs supporting the grille and delimiting the ferret guide conduit. - the ferret guide conduit extends in the must collection chamber, - the ferret guide conduit is more confined than the must collection chamber, characterised in that - the ferret guide conduit comprises a plurality of aligned studs disposed in the must collection chamber between the wall of the vat and the grille , the studs supporting the grille and delimiting the ferret guide conduit.
Fused tuckstone defining - a lower surface (20 3 ) comprising: - a support surface (20 14 ) intended to rest on the metallic structure of a glass furnace, - a tank surface (20 12 ) intended to face an upper edge of a tank of said glass furnace, - a lower transition surface (20 14-12 ) connecting the support surface and the tank surface, - an upper surface (20 5 ) comprising: - a superstructure surface (20 26 ) intended to receive a side wall of a superstructure of said glass furnace, - an upper transition surface (20 26-3 ) connecting the superstructure surface (20 26 ) and the lower surface (20 3 ), characterized in that at least a part of the lower transition surface has a crystal density of more than four times the crystal density at a depth of 4 centimeters below said lower transition surface, such a surface being described as a surface with "skin microstructure", a crystal density being evaluated by the number of crystals having a surface area of more than 12 μm 2 per mm 2 of surface after polishing, the crystal density at said depth being evaluated over the surface exposed after cutting of the tuckstone to said depth. - a lower surface (20 3 ) comprising: - a support surface (20 14 ) intended to rest on the metallic structure of a glass furnace, - a tank surface (20 12 ) intended to face an upper edge of a tank of said glass furnace, - a lower transition surface (20 14-12 ) connecting the support surface and the tank surface, - a support surface (20 14 ) intended to rest on the metallic structure of a glass furnace, - a tank surface (20 12 ) intended to face an upper edge of a tank of said glass furnace, - a lower transition surface (20 14-12 ) connecting the support surface and the tank surface, - an upper surface (20 5 ) comprising: - a superstructure surface (20 26 ) intended to receive a side wall of a superstructure of said glass furnace, - an upper transition surface (20 26-3 ) connecting the superstructure surface (20 26 ) and the lower surface (20 3 ), - a superstructure surface (20 26 ) intended to receive a side wall of a superstructure of said glass furnace, - an upper transition surface (20 26-3 ) connecting the superstructure surface (20 26 ) and the lower surface (20 3 ),
A method for predicting responsiveness to an antagonist of an inhibitory immune checkpoint and/or an agonist of a stimulatory immune checkpoint comprising: determining the RNA expression level of at least one gene selected from Table 2B in a sample comprising cancer cells or nucleic acids derived therefrom from the subject wherein the determined RNA expression level is used to identify the subject as having a cancer in which the STING/TBK1/IRF3 pathway is activated due to a deficiency in DNA damage repair and thereby predict responsiveness to an antagonist of an inhibitory immune checkpoint and/or an agonist of a stimulatory immune checkpoint.
An induction sealing device comprising a main body , a magnetic field concentrator held in said main body, a conductive element , characterized in that said magnetic field concentrator is injection molded, and said main body is provided with at least one hole for gating material for forming said magnetic field concentrator into an interior of said main body.
A method for establishing a backhaul link, performed by a base station, the method comprising: broadcasting system information to cause a specified terminal, which has established a first communication link with a core network, to receive the system information to return backhaul link establishment signaling; receiving the backhaul link establishment signaling returned by the specified terminal, the backhaul link establishment signaling being configured to indicate that the specified terminal has accessed the core network and may establish a backhaul link for the base station, the backhaul link establishment signaling being a Radio Resource Control, RRC, signaling, an information element of the signaling carrying a backhaul link establishment identifier; and sending a confirmation message to the specified terminal to cause the specified terminal to establish a second communication link with the base station after receiving the backhaul link establishment signaling, the second communication link and the first communication link forming the backhaul link; wherein different time resources are configured for a communication link between the base station and any terminal in coverage of the base station and the backhaul link. broadcasting system information to cause a specified terminal, which has established a first communication link with a core network, to receive the system information to return backhaul link establishment signaling; receiving the backhaul link establishment signaling returned by the specified terminal, the backhaul link establishment signaling being configured to indicate that the specified terminal has accessed the core network and may establish a backhaul link for the base station, the backhaul link establishment signaling being a Radio Resource Control, RRC, signaling, an information element of the signaling carrying a backhaul link establishment identifier; and sending a confirmation message to the specified terminal to cause the specified terminal to establish a second communication link with the base station after receiving the backhaul link establishment signaling, the second communication link and the first communication link forming the backhaul link; wherein different time resources are configured for a communication link between the base station and any terminal in coverage of the base station and the backhaul link.
A moisture-permeable film formed by a composition comprising polyurethane (A) and a hydrophilic acrylic polymer (B), wherein the hydrophilic acrylic polymer (B) is a polymer of a hydrophilic acrylic monomer (b1) containing an acrylic monomer (b1-1) having an amide group and an acrylic monomer (b1-2) having an oxyethylene group, the amide group having an alkyl-substituted nitrogen atom.
A wireless communication apparatus comprising: a resource allocation unit to perform resource allocation of selecting a frequency channel with best transmission quality from a plurality of frequency channels on the basis of transmission quality of each frequency channel of the plurality of frequency channels, and allocating a time slot in a frequency hopping pattern corresponding to the selected frequency channel as a time slot to be used for transmission of a data sequence; and a control station to control transmission of the data sequence using the time slot allocated by the resource allocation unit and the frequency channel, characterized in that when performing a repeated transmission on a plurality of data sequences, the resource allocation unit is configured to perform the resource allocation such that the expression max ∏ j = 0 M − 1 P C i , j , i = 0 to N - 1 has a minimum value, where N denotes the number of data sequences, M denotes the number of repeated transmissions in one frame, C i,j represents a frequency channel of a slot used for an i-th data sequence in a j-th repeated transmission, P(C i,j ) represents a transmission error rate of the frequency channel C i,j , and max () is an operator for extracting the maximum value within i=0 to N-1. a resource allocation unit to perform resource allocation of selecting a frequency channel with best transmission quality from a plurality of frequency channels on the basis of transmission quality of each frequency channel of the plurality of frequency channels, and allocating a time slot in a frequency hopping pattern corresponding to the selected frequency channel as a time slot to be used for transmission of a data sequence; and a control station to control transmission of the data sequence using the time slot allocated by the resource allocation unit and the frequency channel, characterized in that when performing a repeated transmission on a plurality of data sequences, the resource allocation unit is configured to perform the resource allocation such that the expression max ∏ j = 0 M − 1 P C i , j , i = 0 to N - 1 has a minimum value, where N denotes the number of data sequences, M denotes the number of repeated transmissions in one frame, C i,j represents a frequency channel of a slot used for an i-th data sequence in a j-th repeated transmission, P(C i,j ) represents a transmission error rate of the frequency channel C i,j , and max () is an operator for extracting the maximum value within i=0 to N-1.
A multilayer identity article , comprising: a first multilayer substrate , comprising: greater than or equal to 16 layers of a first polymer, preferably 16 to 512 layers of a first polymer; and greater than or equal to 16 layers of a second polymer, preferably 16 to 512 layers of a second polymer; wherein the layers of the first polymer and the layers of the second polymer are present in a ratio of 1:4 to 4:1, preferably the ratio is 1:1; a first protective layer ; and a first identification layer between the first protective layer and the first multilayer substrate ; wherein the first identification layer comprises information, and wherein the first protective layer prevents alteration thereof; and wherein the first polymer has a different composition than the second polymer. a first multilayer substrate , comprising: greater than or equal to 16 layers of a first polymer, preferably 16 to 512 layers of a first polymer; and greater than or equal to 16 layers of a second polymer, preferably 16 to 512 layers of a second polymer; wherein the layers of the first polymer and the layers of the second polymer are present in a ratio of 1:4 to 4:1, preferably the ratio is 1:1; greater than or equal to 16 layers of a first polymer, preferably 16 to 512 layers of a first polymer; and greater than or equal to 16 layers of a second polymer, preferably 16 to 512 layers of a second polymer; wherein the layers of the first polymer and the layers of the second polymer are present in a ratio of 1:4 to 4:1, preferably the ratio is 1:1; a first protective layer ; and a first identification layer between the first protective layer and the first multilayer substrate ; wherein the first identification layer comprises information, and wherein the first protective layer prevents alteration thereof; and wherein the first polymer has a different composition than the second polymer.
An impact energy absorber for absorbing an impact energy on a vehicle, the impact energy absorber comprising: a first wedge shaped part having a first outer surface and a second outer surface ; a second wedge shaped part having a third outer surface and a fourth outer surface , and the first wedge shaped part and the second wedge shaped part are adjoined to form a wedge shaped opening between the second surface and the third surface , which second outer surface and third outer surface are facing each other; wherein at least a first rib element is arranged in the wedge shaped opening , the first rib element extending parallel to an impact line from the second outer surface in the direction of the third outer surface along an impact line, and at least one second rib element extending from the third outer surface in the direction of the second outer surface such that the second rib element is in line with the first rib element and wherein, in an undeformed condition, the first rib element and the second rib element are having a distance therebetween. a first wedge shaped part having a first outer surface and a second outer surface ; a second wedge shaped part having a third outer surface and a fourth outer surface , and the first wedge shaped part and the second wedge shaped part are adjoined to form a wedge shaped opening between the second surface and the third surface , which second outer surface and third outer surface are facing each other; wherein at least a first rib element is arranged in the wedge shaped opening , the first rib element extending parallel to an impact line from the second outer surface in the direction of the third outer surface along an impact line, and at least one second rib element extending from the third outer surface in the direction of the second outer surface such that the second rib element is in line with the first rib element and wherein, in an undeformed condition, the first rib element and the second rib element are having a distance therebetween.
A display device (DD, DD-1, DD-2) comprising: a display panel (DP) defining a display area (DA) for displaying an image and a non-display area (NDA) adjacent to the display area (DA), and comprising: a base layer (SUB); a circuit layer (DP-CL) on the base layer (SUB); a light emitting device layer (DP-OLED) on the circuit layer (DP-CL); a thin film sealing layer (TFE) on the light emitting device layer (DP-OLED), and comprising a first upper surface (TFE-U1) and a second upper surface (TFE-U2); and a touch detection unit (TS) comprising: a first sensor part (SP-C) on the first upper surface (TFE-U1); and a second sensor part (SP-S) on the second upper surface (TFE-U2); characterized in that the second upper surface (TFE-U2) has a peak (PK) that protrudes from a reference surface (RL), which is an extension of the first upper surface (TFE-U1), in a direction away from the base layer (SUB), the second sensor part (SP-S) overlaps the peak (PK), and the second sensor part (SP-S) is closer to the non-display area (NDA) than the first sensor part (SP-C). a base layer (SUB); a circuit layer (DP-CL) on the base layer (SUB); a light emitting device layer (DP-OLED) on the circuit layer (DP-CL); a thin film sealing layer (TFE) on the light emitting device layer (DP-OLED), and comprising a first upper surface (TFE-U1) and a second upper surface (TFE-U2); and a touch detection unit (TS) comprising: a first sensor part (SP-C) on the first upper surface (TFE-U1); and a second sensor part (SP-S) on the second upper surface (TFE-U2); characterized in that the second upper surface (TFE-U2) has a peak (PK) that protrudes from a reference surface (RL), which is an extension of the first upper surface (TFE-U1), in a direction away from the base layer (SUB), the second sensor part (SP-S) overlaps the peak (PK), and the second sensor part (SP-S) is closer to the non-display area (NDA) than the first sensor part (SP-C). a first sensor part (SP-C) on the first upper surface (TFE-U1); and a second sensor part (SP-S) on the second upper surface (TFE-U2); characterized in that the second upper surface (TFE-U2) has a peak (PK) that protrudes from a reference surface (RL), which is an extension of the first upper surface (TFE-U1), in a direction away from the base layer (SUB), the second sensor part (SP-S) overlaps the peak (PK), and the second sensor part (SP-S) is closer to the non-display area (NDA) than the first sensor part (SP-C).
Method for determining an emergency stopping point of a motor vehicle , the method comprising the following steps: - determining a driving state of the motor vehicle ; - determining an emergency stopping point in the region of the motor vehicle on the basis of the driving state; characterized in that - the emergency stopping point is determined in such a way that a risk caused by stopping at the determined emergency stopping point does not exceed a predetermined value, the value being determined in dependence on the driving state. - determining a driving state of the motor vehicle ; - determining an emergency stopping point in the region of the motor vehicle on the basis of the driving state; - the emergency stopping point is determined in such a way that a risk caused by stopping at the determined emergency stopping point does not exceed a predetermined value, the value being determined in dependence on the driving state.
Pitch composition comprising a mixture of: - deasphalting pitch, which represents at least 50% by weight, and preferably at least 80% by weight, and preferentially at least 90% by weight, of the total weight of the composition, and - a hydroxide XOH with X = Na or K, which represents from 0.001 to 1% by weight, of the total weight of the composition. - deasphalting pitch, which represents at least 50% by weight, and preferably at least 80% by weight, and preferentially at least 90% by weight, of the total weight of the composition, and - a hydroxide XOH with X = Na or K, which represents from 0.001 to 1% by weight, of the total weight of the composition.