Theranostic apparatus for therapeutic transfer of molecules by means of electroporation comprising: - a main body provided with electronic processor means and data storage means, - input means , such as a keyboard and/or touch screen, - at least one treatment probe provided with an electrode, said electrode being configured to deliver electrical pulse sequences by means of electroporation, - a plurality of probe connectors , for said at least one treatment probe ,hardware and software means configured for displaying data, respectively for providing sound signals, - connection means with respect to an internet network for data transmission, by means of the same, - a power supply circuit, including batteries and a connection interface to an external power source, and - a micro-controller unit , operationally connected to said electronic processor means and data storage means, - at least one detection probe , configured for measuring a plurality of physiological parameters, wherein said probe comprises one or more sensors , configured for measuring a plurality of physiological parameters, having prognostic value, of a subject undergoing the treatment, and wherein said micro controller unit is configured for the acquisition and processing of said physiological parameters having prognostic value, measured by at least one detecting probe , and for the subsequent generation and control of an electroporation pulses sequence, on the basis of said processed physiological parameters having prognostic value, characterized in that said microcontroller unit is further configured for the determination and control of the electroporation pulses sequence for the loco-regional treatment of disorders comprised in the group of solid neoplasm, visceral and pararectal tumors, benign or low malignancy solid viral growths, benign or low malignancy lesions. - a main body provided with electronic processor means and data storage means, - input means , such as a keyboard and/or touch screen, - at least one treatment probe provided with an electrode, said electrode being configured to deliver electrical pulse sequences by means of electroporation, - a plurality of probe connectors , for said at least one treatment probe ,hardware and software means configured for displaying data, respectively for providing sound signals, - connection means with respect to an internet network for data transmission, by means of the same, - a power supply circuit, including batteries and a connection interface to an external power source, and - a micro-controller unit , operationally connected to said electronic processor means and data storage means, - at least one detection probe , configured for measuring a plurality of physiological parameters, wherein said probe comprises one or more sensors , configured for measuring a plurality of physiological parameters, having prognostic value, of a subject undergoing the treatment, and wherein said micro controller unit is configured for the acquisition and processing of said physiological parameters having prognostic value, measured by at least one detecting probe , and for the subsequent generation and control of an electroporation pulses sequence, on the basis of said processed physiological parameters having prognostic value, characterized in that said microcontroller unit is further configured for the determination and control of the electroporation pulses sequence for the loco-regional treatment of disorders comprised in the group of solid neoplasm, visceral and pararectal tumors, benign or low malignancy solid viral growths, benign or low malignancy lesions. <EOS>