mhurhangee/patent-ind-claim-en huggingface dataset:
A method of identifying a therapeutic agent for cancer in an individual, the method comprising: a. providing an adipocyte differentiation signal to human preadipocytes; b. preparing a solid or semi-solid stromal bio-ink, the stromal bio-ink comprising a plurality of stromal cell types, the stromal cell types comprising the human preadipocytes of (a); c. preparing a solid or semi-solid tumor bio-ink, the tumor bio-ink comprising primary cancer cells from the individual; d. bioprinting the stromal bio-ink and the tumor bio-ink from a bioprinter, such that the tumor bio-ink is embedded in the stromal bio-ink and in contact with the stromal bio-ink on all sides; e. maturing the bioprinted stromal and tumor bio-inks in a cell culture media to allow the cells to cohere to form a three-dimensional, engineered, biological construct; f. applying a candidate therapeutic agent to the construct; g. measuring viability of the cancer cells; and h. selecting a therapeutic agent for the individual based on the measured viability of the cancer cells; wherein the bio-inks comprise cells, cells combined with an excipient or extrusion compound, or aggregates of cells, and wherein the stromal bio-ink comprises differentiating human preadipocytes at the time of bioprinting that differentiate into human adipocytes post-bioprinting. a. providing an adipocyte differentiation signal to human preadipocytes; b. preparing a solid or semi-solid stromal bio-ink, the stromal bio-ink comprising a plurality of stromal cell types, the stromal cell types comprising the human preadipocytes of (a); c. preparing a solid or semi-solid tumor bio-ink, the tumor bio-ink comprising primary cancer cells from the individual; d. bioprinting the stromal bio-ink and the tumor bio-ink from a bioprinter, such that the tumor bio-ink is embedded in the stromal bio-ink and in contact with the stromal bio-ink on all sides; e. maturing the bioprinted stromal and tumor bio-inks in a cell culture media to allow the cells to cohere to form a three-dimensional, engineered, biological construct; f. applying a candidate therapeutic agent to the construct; g. measuring viability of the cancer cells; and h. selecting a therapeutic agent for the individual based on the measured viability of the cancer cells; wherein the bio-inks comprise cells, cells combined with an excipient or extrusion compound, or aggregates of cells, and wherein the stromal bio-ink comprises differentiating human preadipocytes at the time of bioprinting that differentiate into human adipocytes post-bioprinting. wherein the bio-inks comprise cells, cells combined with an excipient or extrusion compound, or aggregates of cells, and wherein the stromal bio-ink comprises differentiating human preadipocytes at the time of bioprinting that differentiate into human adipocytes post-bioprinting.
A base station for use in a wireless communication network comprising a relay station capable of relaying communications between the base station and a subscriber station, the base station comprising: a plurality of antennas; and a transmitter coupled to the plurality of antennas and configured to transmit, in a subframe, a plurality of transport blocks for a plurality of Hybrid Automatic Repeat Request, HARQ, processes to the relay station, wherein each transport block corresponds to a different HARQ process. a plurality of antennas; and a transmitter coupled to the plurality of antennas and configured to transmit, in a subframe, a plurality of transport blocks for a plurality of Hybrid Automatic Repeat Request, HARQ, processes to the relay station, wherein each transport block corresponds to a different HARQ process.
A method in a terminal for acquiring paging information during a set of two or more paging occasions, one paging occasion corresponding to a subframe, wherein the method comprises: determining a first subframe of the set of two or more paging occasions, wherein the first subframe is a subframe of a Discovery Reference Signal, DRS, Transmission Window, DTxW; and determining a last subframe of the set of two or more paging occasions, wherein determining the last subframe comprises detecting a DRS transmission from a serving cell of the terminal , and wherein: the terminal is required to attempt to acquire the paging information in any subframe between the first subframe and the last subframe of the set of two of more paging occasions. determining a first subframe of the set of two or more paging occasions, wherein the first subframe is a subframe of a Discovery Reference Signal, DRS, Transmission Window, DTxW; and determining a last subframe of the set of two or more paging occasions, wherein determining the last subframe comprises detecting a DRS transmission from a serving cell of the terminal , and wherein: the terminal is required to attempt to acquire the paging information in any subframe between the first subframe and the last subframe of the set of two of more paging occasions.
A method of determining a tire class of a tire mounted on a wheel of a driving vehicle, the method comprising: obtaining a set of estimated vehicle properties parameters, wherein said vehicle properties parameters are determined based at least one sensor signal received from sensors comprised in said vehicle; determining a tire class based on said set of vehicle properties parameters, characterized in that said vehicle properties parameters are determined based on sensor data indicative of individual tire longitudinal stiffness for at least one wheel or of inverse individual tire longitudinal stiffness for at least one wheel, and sensor data indicative of ambient temperature and/or of individual tire temperature for at least one wheel. obtaining a set of estimated vehicle properties parameters, wherein said vehicle properties parameters are determined based at least one sensor signal received from sensors comprised in said vehicle; determining a tire class based on said set of vehicle properties parameters, characterized in that said vehicle properties parameters are determined based on sensor data indicative of individual tire longitudinal stiffness for at least one wheel or of inverse individual tire longitudinal stiffness for at least one wheel, and sensor data indicative of ambient temperature and/or of individual tire temperature for at least one wheel. sensor data indicative of individual tire longitudinal stiffness for at least one wheel or of inverse individual tire longitudinal stiffness for at least one wheel, and sensor data indicative of ambient temperature and/or of individual tire temperature for at least one wheel.
A garment hanger comprising: a rail engaging portion in the form of a rail engaging hook ; and a stem , wherein, the stem comprises a first section extending from the rail engaging portion , a spacer section extending rearwardly from the stem in a direction that is non-parallel to the span of the rail engaging hook ; and a tail section extending from the spacer section and directed towards the first section , wherein an open loop is formed with an opening (G) between the end of the tail section and the first section of the stem ; and wherein the stem comprises a material that is able to elastically deform to allow a garment onto or off the open loop of the hanger. a rail engaging portion in the form of a rail engaging hook ; and a stem , wherein, the stem comprises a first section extending from the rail engaging portion , a spacer section extending rearwardly from the stem in a direction that is non-parallel to the span of the rail engaging hook ; and a tail section extending from the spacer section and directed towards the first section , wherein an open loop is formed with an opening (G) between the end of the tail section and the first section of the stem ; and wherein the stem comprises a material that is able to elastically deform to allow a garment onto or off the open loop of the hanger.
A semiconductor device comprising: an active pattern (AP1) on a substrate and extending in a first direction (X); a gate structure (GS) on the active pattern (AP1), the gate structure (GS) comprising a gate spacer and a gate electrode , the gate electrode extending in a second direction (Y) different from the first direction (X); a source/drain pattern on at least one side of the gate structure (GS); and a source/drain contact on the source/drain pattern and connected to the source/drain pattern , wherein with respect to an upper surface (AP1_US) of the active pattern (AP1), a height of an upper surface of the gate electrode is same as a height of an upper surface of the source/drain contact and a height of an upper surface of the gate spacer , and the source/drain contact comprises a lower source/drain contact and an upper source/drain contact on the lower source/drain contact , wherein the lower source/drain contact comprises a lower source/drain filling layer and a lower source/drain barrier layer extending along a sidewall of the lower source/drain filling layer , and wherein with respect to the upper surface (AP1_US) of the active pattern (AP1), an upper surface (171_BU) of the lower source/drain filling layer is higher than an upper surface (171_AU) of the lower source/drain barrier layer . an active pattern (AP1) on a substrate and extending in a first direction (X); a gate structure (GS) on the active pattern (AP1), the gate structure (GS) comprising a gate spacer and a gate electrode , the gate electrode extending in a second direction (Y) different from the first direction (X); a source/drain pattern on at least one side of the gate structure (GS); and a source/drain contact on the source/drain pattern and connected to the source/drain pattern , wherein with respect to an upper surface (AP1_US) of the active pattern (AP1), a height of an upper surface of the gate electrode is same as a height of an upper surface of the source/drain contact and a height of an upper surface of the gate spacer , and the source/drain contact comprises a lower source/drain contact and an upper source/drain contact on the lower source/drain contact , wherein the lower source/drain contact comprises a lower source/drain filling layer and a lower source/drain barrier layer extending along a sidewall of the lower source/drain filling layer , and wherein with respect to the upper surface (AP1_US) of the active pattern (AP1), an upper surface (171_BU) of the lower source/drain filling layer is higher than an upper surface (171_AU) of the lower source/drain barrier layer .
Method for the production of containers filled with liquid filling material made from thermally conditioned preforms , in which the filling material is fed into the preform under pressure at a forming and filling station through a filling valve, wherein the filling material is provided by a filling-material source and pumped into the preform by a positive displacement pump provided between the filling-material source and the forming and filling stations with the filling valve open, characterized in that at least two are assigned to each positive displacement pump with the forming and filling stations being supplied with filling material by the positive displacement pump , in particular, being supplied one after the other.
Method for transmitting data between a radio transponder reader and a radio transponder, in which - the radio transponder reader modulates at least one control command onto a radio carrier signal and transmits the modulated radio carrier signal to the radio transponder , - the radio transponder receives the modulated radio carrier signal by means of an inductive antenna arrangement to which a load modulation unit that comprises an alterable load impedance is connected, - a control unit of the radio transponder generates a response signal by controlling an alteration of the load impedance by means of a control signal that has a selected switching impulse frequency and a selected number of switching impulses, characterized in that - the control unit encodes multi-valued at least ternary symbols into the control signal , - symbol values (U-X) are each assigned to switching impulse sequences (10-13) that each have a unique combination of switching impulse frequency, number of switching impulses and phase shift, wherein only combinations whose quotient of the number of switching impulses and the switching impulse frequency is within a prescribed range of values are selected. - the radio transponder reader modulates at least one control command onto a radio carrier signal and transmits the modulated radio carrier signal to the radio transponder , - the radio transponder receives the modulated radio carrier signal by means of an inductive antenna arrangement to which a load modulation unit that comprises an alterable load impedance is connected, - a control unit of the radio transponder generates a response signal by controlling an alteration of the load impedance by means of a control signal that has a selected switching impulse frequency and a selected number of switching impulses, characterized in that - the control unit encodes multi-valued at least ternary symbols into the control signal , - symbol values (U-X) are each assigned to switching impulse sequences (10-13) that each have a unique combination of switching impulse frequency, number of switching impulses and phase shift, wherein only combinations whose quotient of the number of switching impulses and the switching impulse frequency is within a prescribed range of values are selected.
Use of a S1P receptor modulator or agonist in the manufacture of a medicament for the treatment of an autoimmune disease selected from the list consisting of multiple sclerosis, polymyositis, lupus nephritis, rheumatoid arthritis, inflammatory bowel disease and psoriasis, wherein, prior to commencing the administration of the S1P receptor modulator or agonist at the standard daily therapeutic dosage, said S1P receptor modulator or agonist is administered at a daily dosage which is lower than the standard daily therapeutic dosage during an initial period of treatment, wherein the initial period of treatment is 7 days, and wherein the daily dosage during the initial period of treatment is up to 10 fold less than the standard dailydosage.
Turbo engine assembly with a housing , a turbo expander comprising an expander impeller , a first turbo compressor comprising a first compressor impeller and a shaft rotatably mounted on the housing , which connects the expander impeller to the compressor impeller , wherein the first turbo compressor can be exclusively propelled by the turbo expander , characterized in that a second turbo compressor is arranged on the housing with a second compressor impeller , which is connected to the first turbo compressor in parallel or in series, that the second turbo compressor is mechanically decoupled from the first turbo compressor, and that the second compressor impeller can be propelled by means of a gearbox accommodated in the housing and a drive shaft connecting the gearbox to the second compressor impeller .
Honeycomb for combating Varroa mites in bee colonies, - with a preferably dismantable cage for a queen bee, - with openings , preferably in a top portion of the cage for the passage of worker bees or drones, - with a central wall , and - with coupling devices on the cage for securing the cage in a honeycomb , characterized in that the central wall is disposed on an inner side , which faces the inner chamber of the cage, of a back wall of the cage opposite to the top portion and is removably retained on the cage . - with a preferably dismantable cage for a queen bee, - with openings , preferably in a top portion of the cage for the passage of worker bees or drones, - with a central wall , and - with coupling devices on the cage for securing the cage in a honeycomb ,
An air quality-monitoring system , comprising: at least one sensor configured to detect operation of a mechanism within or at a boundary of an indoor environment, wherein the mechanism is external to an air purifier associated with the indoor environment; a persistent memory for storing data about the indoor environment observed by the at least one sensor ; a controller communicatively coupled with the at least one sensor and characterized in that the controller is configured to: assemble the data into an air quality profile associated with that environment; determine, based on a signal from the at least one sensor and on the air quality profile, a likelihood that operation of the mechanism will cause a measure of air quality within the indoor environment to fail one or more air quality criteria; and selectively provide, based on the likelihood, an indication that operation of the mechanism will cause the measure of air quality within the indoor environment to fail the one or more air quality criteria. at least one sensor configured to detect operation of a mechanism within or at a boundary of an indoor environment, wherein the mechanism is external to an air purifier associated with the indoor environment; a persistent memory for storing data about the indoor environment observed by the at least one sensor ; a controller communicatively coupled with the at least one sensor and characterized in that the controller is configured to: assemble the data into an air quality profile associated with that environment; determine, based on a signal from the at least one sensor and on the air quality profile, a likelihood that operation of the mechanism will cause a measure of air quality within the indoor environment to fail one or more air quality criteria; and selectively provide, based on the likelihood, an indication that operation of the mechanism will cause the measure of air quality within the indoor environment to fail the one or more air quality criteria. assemble the data into an air quality profile associated with that environment; determine, based on a signal from the at least one sensor and on the air quality profile, a likelihood that operation of the mechanism will cause a measure of air quality within the indoor environment to fail one or more air quality criteria; and selectively provide, based on the likelihood, an indication that operation of the mechanism will cause the measure of air quality within the indoor environment to fail the one or more air quality criteria.
A catheter device comprising: an axially elongate tubular member comprising an inner lumen, an outer surface, a proximal region, and a distal region, the tubular member comprising a metal helix having a helical gap, and a polymeric potting material disposed within the helical gap; an inner liner extending through the inner lumen of the tubular member and defining an inner lumen of the catheter ; an outer cover on the outer surface of the tubular member ; and a balloon inflation channel disposed between the metal helix and the inner liner , wherein the polymeric potting material disposed within the helical gap is different from the materials of the inner liner and outer cover characterised in that the distal region has an inner diameter to wall thickness ratio of about 16:1 to about 24:1, and a) a lateral flexibility of greater than 1,200 degrees of deflection per 11.3 Newton-centimetres (1,200 degrees of deflection per pound-force inch) and/or b) a kink radius of about 4.4196 millimetres +/-0.2032 millimetres (0.174 inch +/-0.008 inch) or less and/or a tensile strength of 22N ultimate tensile strength (UTS). an axially elongate tubular member comprising an inner lumen, an outer surface, a proximal region, and a distal region, the tubular member comprising a metal helix having a helical gap, and a polymeric potting material disposed within the helical gap; an inner liner extending through the inner lumen of the tubular member and defining an inner lumen of the catheter ; an outer cover on the outer surface of the tubular member ; and a balloon inflation channel disposed between the metal helix and the inner liner , wherein the polymeric potting material disposed within the helical gap is different from the materials of the inner liner and outer cover characterised in that the distal region has an inner diameter to wall thickness ratio of about 16:1 to about 24:1, and a) a lateral flexibility of greater than 1,200 degrees of deflection per 11.3 Newton-centimetres (1,200 degrees of deflection per pound-force inch) and/or b) a kink radius of about 4.4196 millimetres +/-0.2032 millimetres (0.174 inch +/-0.008 inch) or less and/or a tensile strength of 22N ultimate tensile strength (UTS).
A laminate for biosensor comprising: a pressure-sensitive adhesive layer for attaching to a living body; and a substrate layer disposed on the upper face of the pressure-sensitive adhesive layer, wherein the laminate for biosensor includes a moisture barrier layer disposed inside the pressure-sensitive adhesive layer and having an exposed lower face, and a probe embedded in the moisture barrier layer and having a lower face exposed from the lower face of the moisture barrier layer. a pressure-sensitive adhesive layer for attaching to a living body; and a substrate layer disposed on the upper face of the pressure-sensitive adhesive layer, wherein the laminate for biosensor includes a moisture barrier layer disposed inside the pressure-sensitive adhesive layer and having an exposed lower face, and a probe embedded in the moisture barrier layer and having a lower face exposed from the lower face of the moisture barrier layer.