mhurhangee/patent-ind-claim-en huggingface dataset:
A method of determining the likelihood of increased tumor load of prostate cancer in a subject, comprising a. measuring the expression level of ZFP36 in a first sample from the subject comprising cancer cells collected from a tumor lesion, a draining lymph node, or a body fluid such as blood; and b. comparing the measured expression level of ZFP36 in the first sample from the subject to the expression level of ZFP36 in a first control sample; c. measuring an expression level of PTEN in a second sample from the subject comprising cancer cells collected from a tumor lesion, a draining lymph node, or a body fluid such as blood; and d. comparing the measured expression level of PTEN in the second sample to the expression level of PTEN in a second control sample, wherein the likelihood of increased tumor load of prostate cancer is higher if the expression level of ZFP36 in the first sample from the subject is lower than the expression level of ZFP36 in the first control sample, and the expression level of PTEN in the second sample from the subject is lower than the expression level of PTEN in the second control sample, and wherein the likelihood of increased tumor load of prostate cancer is lower if the expression level of ZFP36 in the first sample from the subject is about the same as or higher than the expression level of ZFP36 in the first control sample, and the expression level of PTEN in the second sample from the subject is about the same as or higher than the expression level of PTEN in the second control sample. a. measuring the expression level of ZFP36 in a first sample from the subject comprising cancer cells collected from a tumor lesion, a draining lymph node, or a body fluid such as blood; and b. comparing the measured expression level of ZFP36 in the first sample from the subject to the expression level of ZFP36 in a first control sample; c. measuring an expression level of PTEN in a second sample from the subject comprising cancer cells collected from a tumor lesion, a draining lymph node, or a body fluid such as blood; and d. comparing the measured expression level of PTEN in the second sample to the expression level of PTEN in a second control sample,
Jet regulator having a jet regulator housing in the housing interior space of which at least one flow rectifier is provided which has an inflow-side first insert part and a second insert part , disposed downstream in the flow direction, which are insertable into the housing interior space of the jet regulator housing and which have in each case one encircling external holding ring , wherein a mesh or net structure from mutually crossing or contacting webs is provided in each case on the internal circumference of the holding ring of the respective insert part , one mesh or net structure from mutually crossing or contacting webs which is oriented transversely to the flow direction in each case is provided, of which the at least one inflow-side first insert part has a group of radially oriented webs which at intersection points or contact points cross or contact a group of concentrically encircling webs, and having at least one aeration opening which penetrates a housing circumferential wall of the jet regulator , wherein at least one outlet opening that extends in the circumferential direction across the at least one aeration opening is provided in the mesh or net structure at least of the inflow-side first insert part characterized in that of the radially oriented webs of the first insert part , the webs that are oriented in the direction towards the at least one aeration opening terminate in each case by way of a free external end at a spacing from the encircling holding ring of the first insert part , and in that webs , which when viewed in a projection in the longitudinal direction of the jet regulator, are disposed on the first insert part in the extension of the webs , having a free external end, that are oriented in the direction toward at least one aeration opening , are held on the internal circumference on the holding ring of the second insert part , disposed downstream in the flow direction, and are configured as web stumps such that the stump ends thereof in the projection reach up to the free external end of the webs on the first insert part .
An electric machine, comprising: a stator having a plurality of coils ; and a rotor having a plurality of magnets , the plurality of coils and magnets circumferentially positioned around the electrical machine with respect to an axis of rotation of the rotor , the plurality of magnets configured to interact with the plurality of coils across an air gap to create flux paths parallel to the axis of rotation of the rotor when a respective magnet is aligned with a respective coil, wherein the coils and magnets have an alternating north-south pole arranged in the axis direction such that each of at least some of the plurality of coils simultaneously interact with two different magnets across two respective air gaps when the respective two different magnets are respectively aligned with the coil . a stator having a plurality of coils ; and a rotor having a plurality of magnets , the plurality of coils and magnets circumferentially positioned around the electrical machine with respect to an axis of rotation of the rotor , the plurality of magnets configured to interact with the plurality of coils across an air gap to create flux paths parallel to the axis of rotation of the rotor when a respective magnet is aligned with a respective coil, wherein the coils and magnets have an alternating north-south pole arranged in the axis direction such that each of at least some of the plurality of coils simultaneously interact with two different magnets across two respective air gaps when the respective two different magnets are respectively aligned with the coil .
A method for fabricating an integrated micro LED display comprising: for each of red, green and blue micro LED dies comprising respective red, green and blue arrays of micro LEDs fabricated on respective first substrates, attaching the micro LED array to a CMOS die , the CMOS die comprising an array of pixel drivers fabricated on a CMOS substrate , wherein attaching the micro LED array to the CMOS die comprises: transferring the micro LED array to a second substrate by use of an adhesive , including separating the first substrate from the micro LED array, the micro LED array supported by the second substrate; for the green and blue micro LED arrays: while the micro LED array is supported by the second substrate, removing adhesive in areas between the micro LEDs to increase a vertical clearance in the areas between the micro LEDs; aligning and bonding bonding metal pads for the micro LED array supported by the second substrate to corresponding bonding metal pads for the array of pixel drivers; and removing the second substrate by releasing the adhesive before bonding the next micro LED array; wherein the micro LED arrays are attached to the CMOS die in an order of the red micro LED array, then the green micro LED array, and then the blue micro LED array. transferring the micro LED array to a second substrate by use of an adhesive , including separating the first substrate from the micro LED array, the micro LED array supported by the second substrate; for the green and blue micro LED arrays: while the micro LED array is supported by the second substrate, removing adhesive in areas between the micro LEDs to increase a vertical clearance in the areas between the micro LEDs; aligning and bonding bonding metal pads for the micro LED array supported by the second substrate to corresponding bonding metal pads for the array of pixel drivers; and removing the second substrate by releasing the adhesive before bonding the next micro LED array; wherein the micro LED arrays are attached to the CMOS die in an order of the red micro LED array, then the green micro LED array, and then the blue micro LED array.
An adaptive beamforming system configured to process at least two input signals to provide an output signal, wherein a first input signal of the at least two input signals includes a desired signal as a main component and a second input signal of the at least two input signals includes an undesired signal as main component; the system comprising: an error extraction block configured to adaptively process the second input signal and at least one of the first input signal and the output signal to provide an estimated undesired signal representative of an estimate of undesired signal components included in the first input signal; a subtractor configured to take the difference between the estimated undesired signal and the first input signal to provide the output signal; a beamforming block configured to process two or more microphone signals to provide one or more beam signals; and a beamsteering block configured to process the one or more beam signals, wherein processing the one or more beam signals comprises detecting the desired signal and the undesired signal from the one or more beam signals, the desired signal representative of a beam of sound waves pointing towards a desired source, and the undesired signal representative of a beam of sound waves pointing towards a noise source. an error extraction block configured to adaptively process the second input signal and at least one of the first input signal and the output signal to provide an estimated undesired signal representative of an estimate of undesired signal components included in the first input signal; a subtractor configured to take the difference between the estimated undesired signal and the first input signal to provide the output signal; a beamforming block configured to process two or more microphone signals to provide one or more beam signals; and a beamsteering block configured to process the one or more beam signals, wherein processing the one or more beam signals comprises detecting the desired signal and the undesired signal from the one or more beam signals, the desired signal representative of a beam of sound waves pointing towards a desired source, and the undesired signal representative of a beam of sound waves pointing towards a noise source.
A ball joint comprising a ring-shaped outer housing which consists of at least one sheet metal sleeve, a ring-shaped inner housing which is firmly received in the outer housing in the axial direction and which consists of at least one metal sleeve, a bearing shell received in the inner housing , and a ball stud which is received in the bearing shell , characterized in that two support rings are provided between the inner housing and the outer housing , which are welded to the inner housing and the outer housing , a free space (F) being provided between the inner wall of the outer housing and the outer wall of the inner housing .
A multilayered laminate, comprising (a) a support substrate having at least one releasable major surface; (b) a transparent overcoat formed of a first coating composition on the releasable major surface of the support substrate, wherein the first coating composition comprises an aqueous polymer dispersion having a particle size in the range of 30 to 400 nm; (c) a stone-like topcoat system on the transparent overcoat, wherein the stone-like topcoat system comprises a multicolored spot layer and a background color layer, wherein the multicolored spot layer is formed from a third coating composition comprising color concentrate particles protected by a hydrophilic clay colloid and having one or more hues; (d) an adhesive primer coat formed of a second coating composition on the stone-like topcoat system, wherein the second coating composition comprises an aqueous polymer dispersion selected from aqueous acrylic dispersions, aqueous organic silicone dispersions and aqueous vinyl acetate dispersions, wherein the transparent overcoat in the multilayered laminate, when released from the support substrate, has a gloss of at least 60% at 60°, measured according to GB/T 1743-1989. (a) a support substrate having at least one releasable major surface; (b) a transparent overcoat formed of a first coating composition on the releasable major surface of the support substrate, wherein the first coating composition comprises an aqueous polymer dispersion having a particle size in the range of 30 to 400 nm; (c) a stone-like topcoat system on the transparent overcoat, wherein the stone-like topcoat system comprises a multicolored spot layer and a background color layer, wherein the multicolored spot layer is formed from a third coating composition comprising color concentrate particles protected by a hydrophilic clay colloid and having one or more hues; (d) an adhesive primer coat formed of a second coating composition on the stone-like topcoat system, wherein the second coating composition comprises an aqueous polymer dispersion selected from aqueous acrylic dispersions, aqueous organic silicone dispersions and aqueous vinyl acetate dispersions,
Method for communication between an application and a physical object by way of a digital twin of the physical object , wherein description data that contain properties of digital data of the physical object are produced based on a description metamodel, wherein communication information is created and, in order to create the digital twin , the description data and the communication information and a name of the physical object are combined and stored in a directory as information that gives the application the ability to communicate with the digital twin , wherein the application thus receives all of the information required for a data exchange with the physical object by reading the directory and uses it for a data exchange with the physical object .
A compressor system which is designed to provide compressed air with a reduced carbon dioxide concentration, with a compressor which comprises at least one compressor stage (3, 4, 5, 6,) at least one membrane separator which is arranged at the outlet side of the at least one compressor stage , a return conduit which connects a permeate outlet of the membrane separator to the inlet side of a compressor stage which is situated upstream of the membrane separator , as well as at least one carbon dioxide separator which is arranged in the return conduit and which is designed to reduce the carbon dioxide concentration in a rinsing airflow which is fed through the return conduit to the inlet side of the upstream compressor stages .
: A process for the preparation of Sugammadex or its salts, preferably Sugammadex sodium, which comprises: a) reacting 3-mercaptopropionic acid of formula (III) with an ionic base to obtain the mono-salt of formula (IV), wherein M is an alkaline metal; b) isolating the mono-salt of formula (IV); c) reacting the mono-salt of formula (IV) with the compound of formula (II) or a hydrate or solvate thereof, in the presence of an ionic base, wherein X is CI, Br, I, or OSO 2 R, wherein R is C 1 -C 4 alkyl, optionally substituted by F, Cl, Br or I; phenyl or C 1 -C 4 alkyl-phenyl. a) reacting 3-mercaptopropionic acid of formula (III) with an ionic base to obtain the mono-salt of formula (IV), wherein M is an alkaline metal; b) isolating the mono-salt of formula (IV); c) reacting the mono-salt of formula (IV) with the compound of formula (II) or a hydrate or solvate thereof, in the presence of an ionic base, wherein X is CI, Br, I, or OSO 2 R, wherein R is C 1 -C 4 alkyl, optionally substituted by F, Cl, Br or I; phenyl or C 1 -C 4 alkyl-phenyl.
Device for actuating a gearwheel (4 to 7), configured as a loose wheel, of a transmission device , which gearwheel (4 to 7) is rotatably mounted on a shaft and can be transferred, via at least one activating device having an actuator which is at least partially arranged in the interior of the shaft and can be operated by means of a fluid pressure medium, into an activated state in which the gearwheel (4 to 7) is connected to the shaft in a rotationally fixed manner, and wherein the actuating force required for activation or deactivation is applied to the gearwheel (4 to 7) from the interior of the shaft , characterized in that the at least one actuator is designed as a motor which is connected to the shaft in a rotationally fixed manner and is arranged therein, wherein the operative connection between a motor output shaft of the motor and the gearwheel (4 to 7) to be actuated is configured with a rotational speed decoupling between the motor output shaft and the shaft .
A subsea production fluid sample collection system comprising: a subsea hydraulic circuit having a subsea hydraulic circuit receptacle in fluid communication with a production fluid in a hydrocarbon production system, a connection apparatus and a sample collection vessel ; wherein the connection apparatus comprises a longitudinal body configured to be removably docked with the subsea hydraulic circuit receptacle to connect the hydraulic circuit to the hydrocarbon production system, the longitudinal body comprising a plurality of radial ports axially displaced along the body; wherein the body comprises an axial bore accommodating a spool having at least one fluid barrier ; and wherein the spool and fluid barrier are actuable to be axially moved in the bore to control axial flow paths along the bore between the plurality of radial ports ; and wherein the hydraulic circuit is configured to enable the production fluid to be delivered to the sample collection vessel via the connection apparatus . a subsea hydraulic circuit having a subsea hydraulic circuit receptacle in fluid communication with a production fluid in a hydrocarbon production system, a connection apparatus and a sample collection vessel ; wherein the connection apparatus comprises a longitudinal body configured to be removably docked with the subsea hydraulic circuit receptacle to connect the hydraulic circuit to the hydrocarbon production system, the longitudinal body comprising a plurality of radial ports axially displaced along the body; wherein the body comprises an axial bore accommodating a spool having at least one fluid barrier ; and wherein the spool and fluid barrier are actuable to be axially moved in the bore to control axial flow paths along the bore between the plurality of radial ports ; and wherein the hydraulic circuit is configured to enable the production fluid to be delivered to the sample collection vessel via the connection apparatus .
Ready-to-use device for affixing a visual marking to a face to be marked of a rigid substrate, in particular the face to be marked of a vehicle, more especially an aircraft or spacecraft, which, in the ready state for its implementation, comprises an assembly which is substantially inextensible, has a certain degree of flexibility and forms a thin and flat coherent multilayer stack including, from rear to front: - protective back , limited by a peripheral edge , on the front face of which is situated the multilayer stack, able to be removed by peeling in order to implement the device, - thin marked substrate , provided with the marking , limited by a peripheral edge situated short of the peripheral edge of the protective back, having an adhesive rear face cooperating with the front face of the protective back and able, during the implementation of the device, to secure the marked substrate to the face to be marked, - a stencil limited by a peripheral edge , comprising a window limited by an edge situated beyond the peripheral edge of the marked support which is situated level with the window , having an adhesive rear face cooperating with the front face of the protective back and able, during the implementation of the device , to ensure first of all a certain degree of securement of the stencil to the face to be marked and then to allow the removal of the stencil by peeling, - an application obverse , limited by a peripheral edge , with an adhesion of its rear face and of the front face of the stencil designed, during the implementation of the device to allow the removal of the application obverse by peeling. - protective back , limited by a peripheral edge , on the front face of which is situated the multilayer stack, able to be removed by peeling in order to implement the device, - thin marked substrate , provided with the marking , limited by a peripheral edge situated short of the peripheral edge of the protective back, having an adhesive rear face cooperating with the front face of the protective back and able, during the implementation of the device, to secure the marked substrate to the face to be marked, - a stencil limited by a peripheral edge , comprising a window limited by an edge situated beyond the peripheral edge of the marked support which is situated level with the window , having an adhesive rear face cooperating with the front face of the protective back and able, during the implementation of the device , to ensure first of all a certain degree of securement of the stencil to the face to be marked and then to allow the removal of the stencil by peeling, - an application obverse , limited by a peripheral edge , with an adhesion of its rear face and of the front face of the stencil designed, during the implementation of the device to allow the removal of the application obverse by peeling.
A method of detecting heavy rain or hail on a blade on a wind turbine generator , comprising the following acts: - measuring sensory input from the wind turbine generator ; - identifying signatures of heavy rain or hail on the blade from the sensory input , characterized in that , the act of measuring is performed by means of accelerometers as vibration sensors . - measuring sensory input from the wind turbine generator ; - identifying signatures of heavy rain or hail on the blade from the sensory input ,
Flexible water-based wall-surface heating and cooling system, comprising a heat-transfer medium pipe , a lower base-profile , an upper base-profile , a first guide-profile , a second guide-profile and a first to last horizontally placed heat-exchange profiles , in which the heat-transfer medium pipe is inserted, characterized in that the space between the heat exchange profiles in which the heat-transfer medium pipe is located has a circular closed shape.
An open roof construction for a vehicle having an opening in its fixed roof , comprising a stationary part to be attached to the vehicle roof and at least one closure element which is movably supported by said stationary part and which can be adjusted by means of a driving unit including a driving element , wherein said closure element is movable between a closed position for closing the roof opening, and an open, rearward position for being at least partially above the roof area behind the roof opening, in which the roof opening is at least partially released, wherein said stationary part is fitted with at least one front guide track extending at least along a part of the roof opening , and a fixed rear guide track substantially rearward of the roof opening, the closure element being supported near its front side by a front support which is movably guided by said front guide track , and which is supported rearwards thereof by a rear support including a lifting device and a guiding device for engagement in said rear guide track upon rearward movement of the closure element , the lifting device includes a height-adjustable, rotatable, movable element (16; 23) which has a slidable forcing mechanism determining the rotation of the lifting device, characterized in that the lifting device is rotatably connected to the stationary part and the guiding device is connected to the closure element , and in that at least the forcing mechanism , the guiding device , and the rear guide track are arranged such with respect to each other that they are substantially in the same lateral position.