A system for treating a diseased heart valve, the system comprising: - a prosthetic heart valve with a self-expandable anchoring support; and - a catheter for transvascular implantation of the prosthetic heart valve with the self-expandable anchoring support, wherein the catheter comprises: a) a cartridge unit for receiving the anchoring support and the prosthetic heart valve in folded form; and b) an internally hollow guide system to which the cartridge unit is releasably attached at the proximal end, the cartridge unit being adjoined by a bendable portion shaped and dimensioned to allow movement of the guide system through a patient's aortic arch characterized by c) a manipulating part fastened to the distal end of the hollow guide system and having operating elements (13.1, 20, 25) for exerting tensile or compressive forces on actuating elements running through the guide system to the cartridge unit and for selectively manipulating parts of the cartridge unit in such a way that individual parts of the prosthetic heart valve with the anchoring support can be released sequentially, wherein for the sequential release of the individual parts of the prosthetic heart valve with the anchoring support, the parts of the cartridge unit are moved radially about their longitudinal axis and/or laterally in proximal and distal directions, wherein the actuating elements are designed as traction and pressure means and are guided through the interior of the guide system ; wherein a movement of the actuating elements can be triggered via the operating elements (13.1, 20, 25), wherein the movement of the corresponding actuating elements takes place in a metered form, for example with corresponding transmission ratios, and is limited at least by end stops or detent settings. - a prosthetic heart valve with a self-expandable anchoring support; and - a catheter for transvascular implantation of the prosthetic heart valve with the self-expandable anchoring support, a) a cartridge unit for receiving the anchoring support and the prosthetic heart valve in folded form; and b) an internally hollow guide system to which the cartridge unit is releasably attached at the proximal end, the cartridge unit being adjoined by a bendable portion shaped and dimensioned to allow movement of the guide system through a patient's aortic arch characterized by c) a manipulating part fastened to the distal end of the hollow guide system and having operating elements (13.1, 20, 25) for exerting tensile or compressive forces on actuating elements running through the guide system to the cartridge unit and for selectively manipulating parts of the cartridge unit in such a way that individual parts of the prosthetic heart valve with the anchoring support can be released sequentially, wherein for the sequential release of the individual parts of the prosthetic heart valve with the anchoring support, the parts of the cartridge unit are moved radially about their longitudinal axis and/or laterally in proximal and distal directions, wherein the actuating elements are designed as traction and pressure means and are guided through the interior of the guide system ; wherein a movement of the actuating elements can be triggered via the operating elements (13.1, 20, 25), wherein the movement of the corresponding actuating elements takes place in a metered form, for example with corresponding transmission ratios, and is limited at least by end stops or detent settings. <EOS>