mhurhangee/patent-ind-claim-en huggingface dataset:
A method of deconvoluting genomes of prokaryotic organisms in a microbiome sample, said method comprising the steps of: a) sequencing nucleic acids of the prokaryotic organisms comprised in a sample obtained from a subject using single-molecule long reads sequencing technology, wherein the sequencing comprises the step of identifying methylated nucleotides, and at least one of the steps of: i. sequencing single molecule reads of nucleic acids; ii. assembling contigs from single molecule reads of the nucleic acids; and b) assigning a methylation score reflecting the extent of methylation for sequence motifs of the nucleic acids on the assembled contig and/or the single molecule read; c) applying motif filtering to identify sequence motifs with methylation scores indicating methylation on the assembled contigs and/or the single molecule reads; d) determining nucleic acid methylation profiles of the assembled contigs or the single molecule reads in the microbiome sample based on motifs identified in step (c); e) separating the assembled contigs and/or the single molecule reads into bins corresponding to distinct prokaryotic organisms based on the methylation profiles of step (d); f) assembling the bins of step (e), thereby obtaining assembled genomes of the distinct bacterial organisms in the microbiome sample, thereby deconvoluting genomes of the prokaryotic organisms in a microbiome sample. a) sequencing nucleic acids of the prokaryotic organisms comprised in a sample obtained from a subject using single-molecule long reads sequencing technology, wherein the sequencing comprises the step of identifying methylated nucleotides, and at least one of the steps of: i. sequencing single molecule reads of nucleic acids; ii. assembling contigs from single molecule reads of the nucleic acids; and i. sequencing single molecule reads of nucleic acids; ii. assembling contigs from single molecule reads of the nucleic acids; and b) assigning a methylation score reflecting the extent of methylation for sequence motifs of the nucleic acids on the assembled contig and/or the single molecule read; c) applying motif filtering to identify sequence motifs with methylation scores indicating methylation on the assembled contigs and/or the single molecule reads; d) determining nucleic acid methylation profiles of the assembled contigs or the single molecule reads in the microbiome sample based on motifs identified in step (c); e) separating the assembled contigs and/or the single molecule reads into bins corresponding to distinct prokaryotic organisms based on the methylation profiles of step (d); f) assembling the bins of step (e), thereby obtaining assembled genomes of the distinct bacterial organisms in the microbiome sample,
Agent for use in the treatment of excessive LDL levels in humans, containing propionic acid or a physiologically acceptable propionic acid salt in a daily dosage of 0.5 to 1.5 g.
A generation device comprising: a sensing unit configured to sense anomaly of a network based on information having a plurality of items related to communication in the network; an identification unit configured to identify a cause of anomaly corresponding to each piece of the information when anomaly is sensed by the sensing unit; and a pattern generation unit configured to generate, based on values of the items in the information and the cause of anomaly identified by the identification unit, a cause-of-anomaly pattern for each predetermined set of pieces of the information; a determination unit to determine whether the cause-of-anomaly pattern is identical to a previously generated cause-of-anomaly pattern; and wherein the identification unit identifies, as a cause of anomaly, the cause-of-anomaly pattern determined to be identical by the determination unit . a sensing unit configured to sense anomaly of a network based on information having a plurality of items related to communication in the network; an identification unit configured to identify a cause of anomaly corresponding to each piece of the information when anomaly is sensed by the sensing unit; and a pattern generation unit configured to generate, based on values of the items in the information and the cause of anomaly identified by the identification unit, a cause-of-anomaly pattern for each predetermined set of pieces of the information; a determination unit to determine whether the cause-of-anomaly pattern is identical to a previously generated cause-of-anomaly pattern; and wherein the identification unit identifies, as a cause of anomaly, the cause-of-anomaly pattern determined to be identical by the determination unit .
A memory device , comprising: a command address interface (CA) a plurality of bank group clusters ; each of the bank group clusters comprising a plurality of respective bank groups ; each of the bank groups comprising a plurality of respective memory banks (151a, 151b, 151c, 152a, 152b, 152c, 153a, 153b, 153c, ); wherein successive accesses to different memory banks (151a, 151b, 151c, 152a, 152b, 152c,) that are members of the same bank group have a first command to command delay interval for a first type of command received via the command address interface (CA); successive accesses to memory banks that are members of different bank groups and of the same bank group cluster have a second command to command delay interval for the first type of command received via the command address interface (CA); and characterized by successive accesses to memory banks that are members of different bank group clusters have a third command to command delay interval for the first type of command received via the command address interface (CA), wherein the first command to command delay interval, the second command to command delay interval, and the third command to command delay interval are all not equal. a command address interface (CA) a plurality of bank group clusters ; each of the bank group clusters comprising a plurality of respective bank groups ; each of the bank groups comprising a plurality of respective memory banks (151a, 151b, 151c, 152a, 152b, 152c, 153a, 153b, 153c, ); wherein successive accesses to different memory banks (151a, 151b, 151c, 152a, 152b, 152c,) that are members of the same bank group have a first command to command delay interval for a first type of command received via the command address interface (CA); successive accesses to memory banks that are members of different bank groups and of the same bank group cluster have a second command to command delay interval for the first type of command received via the command address interface (CA); and characterized by successive accesses to memory banks that are members of different bank group clusters have a third command to command delay interval for the first type of command received via the command address interface (CA), wherein the first command to command delay interval, the second command to command delay interval, and the third command to command delay interval are all not equal.
Calibration body for calibrating a camera system , comprising: - an optical calibration element , which is suitable for a calibration of extrinsic and/or intrinsic parameters of the camera system , and - an optical position indicator , which is suitable for sensing an orientation of the optical position indicator with respect to the camera system by the camera system , - wherein the optical calibration element is arranged in a predefined relative position with respect to the optical position indicator , characterized in that the optical position indicator comprises a laser unit , which has a diffractive optical element and is designed to display a pattern independently of a transversal displacement of the camera system with respect to the optical position indicator . - an optical calibration element , which is suitable for a calibration of extrinsic and/or intrinsic parameters of the camera system , and - an optical position indicator , which is suitable for sensing an orientation of the optical position indicator with respect to the camera system by the camera system , - wherein the optical calibration element is arranged in a predefined relative position with respect to the optical position indicator ,
A diagnostic and/or prognostic method comprising: a. analysing the levels of CD5L in a sample using the monoclonal antibody produced by the hybridoma deposited at the BCCM and assigned Accession No. LMBP 12584CB and the monoclonal antibody produced by the hybridoma deposited at the BCCM and assigned Accession No. LMBP 12583 CB; b. comparing the levels of CD5L obtained in step (a) with those analysed in control samples; and c. arriving to a diagnosis/prognosis where the levels in the sample are consistent with those in subjects who have been diagnosed previously. a. analysing the levels of CD5L in a sample using the monoclonal antibody produced by the hybridoma deposited at the BCCM and assigned Accession No. LMBP 12584CB and the monoclonal antibody produced by the hybridoma deposited at the BCCM and assigned Accession No. LMBP 12583 CB; b. comparing the levels of CD5L obtained in step (a) with those analysed in control samples; and c. arriving to a diagnosis/prognosis where the levels in the sample are consistent with those in subjects who have been diagnosed previously.
An aqueous solution for use as disinfectant comprising chlorous acid and at least one compound selected from the group consisting of inorganic and organic acids and their salts and combinations of the inorganic and organic acids and their salts, wherein the pH of said aqueous solution is in the range of 3.2 to 7.0, wherein the aqueous solution comprises chlorous acid produced by a process comprising the steps of reacting an aqueous sodium chlorate solution with a volume and concentration of sulfuric acid or aqueous solution thereof appropriate for maintaining pH of said aqueous solution at 2.3 to 3.4, thereby generating chloric acid, and subsequently adding thereto at least an amount of hydrogen peroxide required for reducing said chloric acid to produce chlorous acid.
A wearable transdermal neurostimulator for modulating a subject's cognitive state, comprising an electrical and mechanical connection between first and second connectors located off-center on a first surface of a housing of the wearable transdermal neurostimulator with first and second connector mates on an electrode apparatus , wherein the first and second connectors are separated from each other on the first surface by between 1.78 cm (0.7 inches) and 2.03 cm (0.8 inches), wherein - the electrode apparatus is configured to be secured to the subject's temple or forehead; and - the electrode apparatus is configured to deliver an asymmetric, pulsed, biphasic current for applying electrical stimulation, wherein the electrode apparatus comprises a first portion and a second portion, wherein the first portion is configured to be adhesively secured to the subject's temple or forehead and the second portion of the electrode apparatus is configured to be adhesively secured to another portion of the subject's head or neck, characterized in that an adaptor unit couples to the first and second connectors and provides a second set of electrode connectors with a separation between them larger than an inter-connector distance on the neurostimulator unit. - the electrode apparatus is configured to be secured to the subject's temple or forehead; and - the electrode apparatus is configured to deliver an asymmetric, pulsed, biphasic current for applying electrical stimulation,
A urea and urethane group containing product comprising one or more species of formula (I) R 1 -O-(C=O)-NH-R 2 -NH-(C=O)-NH-R 3 -NH-[-(C=O)-NH-R 4 -NH-(C=O)-NH-R 3 -NH-] n -(C=O)-NH-R 2 -NH-(C=O)-O-R 1 (I) , wherein R 1 independently represent a non-aromatic hydrocarbyl groups having 14 to 30 carbon atoms; R 2 independently represent alkyl-substituted aromatic hydrocarbyl groups having 7 to 12 carbon atoms; R 3 independently represent hydrocarbyl groups having 2 to 36 carbon atoms, which can be interrupted by 1 to 17 ether oxygen atoms in case of aliphatic hydrocarbyl groups; R 4 independently represent hydrocarbyl groups having 2 to 36 carbon atoms; n is an integer from 0 to 200; and wherein on average from 40 mol-% to 100 mol-% of all R 3 and R 4 groups contained in the one or more species of formula (I) are acyclic aliphatic hydrocarbyl groups which, in case of R 3 , can be interrupted by 1 to 17 ether oxygen atoms. R 1 independently represent a non-aromatic hydrocarbyl groups having 14 to 30 carbon atoms; R 2 independently represent alkyl-substituted aromatic hydrocarbyl groups having 7 to 12 carbon atoms; R 3 independently represent hydrocarbyl groups having 2 to 36 carbon atoms, which can be interrupted by 1 to 17 ether oxygen atoms in case of aliphatic hydrocarbyl groups; R 4 independently represent hydrocarbyl groups having 2 to 36 carbon atoms; n is an integer from 0 to 200; and wherein on average from 40 mol-% to 100 mol-% of all R 3 and R 4 groups contained in the one or more species of formula (I) are acyclic aliphatic hydrocarbyl groups which, in case of R 3 , can be interrupted by 1 to 17 ether oxygen atoms.
A fuel cell system, comprising: a fuel cell configured to generate electricity by an electrochemical reaction of a fuel gas supplied to an anode with an oxidant gas supplied to a cathode; a supply channel configured to supply the fuel gas to the anode; a recycle channel configured to supply an anode off-gas discharged from the anode to the supply channel ; a circulation pump that is arranged in the recycle channel ; a discharge channel that is connected to the recycle channel between the anode and the circulation pump and configured to discharge the anode off-gas to outside; a purge valve that is provided on the discharge channel ; a pressure adjuster configured to adjust a pressure of the fuel gas flowing through the supply channel to be constant; and a controller , wherein: the controller is configured to determine whether a purge operation in which the purge valve is brought into an open state to discharge the anode off-gas to the outside is abnormal, and characterized in that when the controller determines that the purge operation is abnormal, the controller is configured to perform a decreasing operation to decrease a flow rate of the fuel gas supplied to the anode. a fuel cell configured to generate electricity by an electrochemical reaction of a fuel gas supplied to an anode with an oxidant gas supplied to a cathode; a supply channel configured to supply the fuel gas to the anode; a recycle channel configured to supply an anode off-gas discharged from the anode to the supply channel ; a circulation pump that is arranged in the recycle channel ; a discharge channel that is connected to the recycle channel between the anode and the circulation pump and configured to discharge the anode off-gas to outside; a purge valve that is provided on the discharge channel ; a pressure adjuster configured to adjust a pressure of the fuel gas flowing through the supply channel to be constant; and a controller , wherein: the controller is configured to determine whether a purge operation in which the purge valve is brought into an open state to discharge the anode off-gas to the outside is abnormal, and characterized in that the controller is configured to determine whether a purge operation in which the purge valve is brought into an open state to discharge the anode off-gas to the outside is abnormal, and characterized in that when the controller determines that the purge operation is abnormal, the controller is configured to perform a decreasing operation to decrease a flow rate of the fuel gas supplied to the anode.
A method for producing a layer containing impregnated and unidirectionally arranged fibres for use as a prepreg or for a prepreg intended for the production of a fibre-reinforced object, wherein fibres are cut through after production of the layer in several areas at a distance to one another, and wherein cuts formed in this way extend within limits of the prepreg, characterized by the method steps: - Impregnation of the fibres with a slip containing - 10 % v/v to 50 % v/v of ceramic particles, relative to the total volume of the slip, wherein the ceramic particles used are those from the group of oxides, mixed oxides, nitrides, carbonitrides of the elements Al, Si, Zr, Y, Mg, Ca, or carbon, - water, - 10 % v/v to 35 % v/v of alcoholic compound, such as glycerol, relative to the total weight of the ceramic particles in the slip, - Arrangement of the layer produced in this way on a carrier element and subsequent cutting through of the fibres. - Impregnation of the fibres with a slip containing - 10 % v/v to 50 % v/v of ceramic particles, relative to the total volume of the slip, wherein the ceramic particles used are those from the group of oxides, mixed oxides, nitrides, carbonitrides of the elements Al, Si, Zr, Y, Mg, Ca, or carbon, - water, - 10 % v/v to 35 % v/v of alcoholic compound, such as glycerol, relative to the total weight of the ceramic particles in the slip, - 10 % v/v to 50 % v/v of ceramic particles, relative to the total volume of the slip, wherein the ceramic particles used are those from the group of oxides, mixed oxides, nitrides, carbonitrides of the elements Al, Si, Zr, Y, Mg, Ca, or carbon, - water, - 10 % v/v to 35 % v/v of alcoholic compound, such as glycerol, relative to the total weight of the ceramic particles in the slip, - Arrangement of the layer produced in this way on a carrier element and subsequent cutting through of the fibres.
A gastrointestinal device comprising: (a) a sleeve configured to carry fluid from a proximal end to a distal end, wherein the proximal end is configured to be at or proximal to a pyloric orifice of a subject, wherein the distal end is configured to be at or distal to a duodenum of the subject; (b) a wave anchor connected to the sleeve, wherein the wave anchor is configured to be retained within a duodenal bulb of the subject; and (c) a flange positioned proximal to the wave anchor, wherein the flange is configured to resist distal migration of the gastrointestinal device, characterized in that the gastrointestinal device further comprises: (d) a coupling liner, wherein the coupling liner connects the wave anchor to the sleeve at a sleeve-coupling interface, wherein a proximal edge of the coupling liner matches a shape of the wave anchor, wherein the sleeve-coupling interface is at or distal to a distal-most end of the wave anchor. (a) a sleeve configured to carry fluid from a proximal end to a distal end, wherein the proximal end is configured to be at or proximal to a pyloric orifice of a subject, wherein the distal end is configured to be at or distal to a duodenum of the subject; (b) a wave anchor connected to the sleeve, wherein the wave anchor is configured to be retained within a duodenal bulb of the subject; and (c) a flange positioned proximal to the wave anchor, wherein the flange is configured to resist distal migration of the gastrointestinal device,
A system for receiving transportation system status information, comprising: a transaction card ; a card reader ; a display device comprising: a display screen , a driving circuit , an antenna , and a inductive coil ; characterised in that in response to the transaction card sending an informational signal to the card reader indicating that a user is located at a transportation stop, when the inductive coil is in the presence of a proximate electromagnetic field generated by the card reader and the antenna receives a data signal from the card reader generated in response to the informational signal, the data signal containing data that is representative of transportation system status information: the inductive coil delivers power to the driving circuit, in response to the data signal, the driving circuit causes the display screen to display the data that is representative of transportation system status information. a transaction card ; a card reader ; a display device comprising: a display screen , a driving circuit , an antenna , and a inductive coil ; characterised in that in response to the transaction card sending an informational signal to the card reader indicating that a user is located at a transportation stop, when the inductive coil is in the presence of a proximate electromagnetic field generated by the card reader and the antenna receives a data signal from the card reader generated in response to the informational signal, the data signal containing data that is representative of transportation system status information: the inductive coil delivers power to the driving circuit, in response to the data signal, the driving circuit causes the display screen to display the data that is representative of transportation system status information. a display screen , a driving circuit , an antenna , and a inductive coil ; characterised in that in response to the transaction card sending an informational signal to the card reader indicating that a user is located at a transportation stop, when the inductive coil is in the presence of a proximate electromagnetic field generated by the card reader and the antenna receives a data signal from the card reader generated in response to the informational signal, the data signal containing data that is representative of transportation system status information: the inductive coil delivers power to the driving circuit, in response to the data signal, the driving circuit causes the display screen to display the data that is representative of transportation system status information.
A filamentous fungal host cell producing and secreting a heterologous polypeptide of interest, said mutant host cell comprising and expressing a mutated ireA gene encoding a modified IreA polypeptide, said modified IreA polypeptide comprising amino acid substitutions of alanine residues in positions corresponding to positions 81 and 84 in the Aspergillus niger IreA amino acid sequence shown in SEQ ID NO:16 with threonine residues, wherein the modified IreA polypeptide comprises an amino acid sequence at least 70% identical to SEQ ID NO:16 or SEQ ID NO:19.