A device for processing of a 2D X-ray image of an object , comprising: - an input unit ; and - a processing unit ; wherein the input unit is configured to provide shape related information from the object to be irradiated, wherein the shape related information is depth related information; and to provide a generic object model ; and to provide the actual 2D X-ray image of the object; wherein the processing unit is configured to convert X-ray image data in a predetermined area of the 2D X-ray image into specific transmission values based on actually applied X-ray radiation parameters; and the processing unit is configured to determine the shape related information based on the specific transmission values, wherein the X-ray radiation parameters are settings applied for generating X-ray radiation used in acquisition of the actual 2D X-ray image , and wherein the shape related information is water equivalent thickness; wherein the processing unit is configured to segment organs in the 2D X-ray image , and wherein the organs comprises bones or lungs; wherein the processing unit is configured to adapt the generic object model based on the shape related information in order to generate an individual object model , wherein the individual object model is a 3D model of the object and after the adaptation the individual object model matches the 2D X-ray image in terms of transmission and x and y dimensions of the segmented organs; and wherein the processing unit is configured to determine, based on the individual object model , an estimation at what distance a detector was to the object in acquisition of the actual 2D X-ray image and an individual image processing modificator for processing at least one part of the 2D X-ray image ; and the processing unit is configured to apply the individual image processing modificator for processing of the 2D X-ray image for feature analysis . - an input unit ; and - a processing unit ; wherein the input unit is configured to provide shape related information from the object to be irradiated, wherein the shape related information is depth related information; and to provide a generic object model ; and to provide the actual 2D X-ray image of the object; wherein the processing unit is configured to convert X-ray image data in a predetermined area of the 2D X-ray image into specific transmission values based on actually applied X-ray radiation parameters; and the processing unit is configured to determine the shape related information based on the specific transmission values, wherein the X-ray radiation parameters are settings applied for generating X-ray radiation used in acquisition of the actual 2D X-ray image , and wherein the shape related information is water equivalent thickness; wherein the processing unit is configured to segment organs in the 2D X-ray image , and wherein the organs comprises bones or lungs; wherein the processing unit is configured to adapt the generic object model based on the shape related information in order to generate an individual object model , wherein the individual object model is a 3D model of the object and after the adaptation the individual object model matches the 2D X-ray image in terms of transmission and x and y dimensions of the segmented organs; and wherein the processing unit is configured to determine, based on the individual object model , an estimation at what distance a detector was to the object in acquisition of the actual 2D X-ray image and an individual image processing modificator for processing at least one part of the 2D X-ray image ; and the processing unit is configured to apply the individual image processing modificator for processing of the 2D X-ray image for feature analysis . <EOS>