mhurhangee/patent-ind-claim-en huggingface dataset:
A method for identifying and quantifying an overrepresented nucleic acid impurity in a composition comprising a parvoviral vector and wherein the method comprises the steps of: a) subjecting the composition to nucleic acid sequencing to obtain random reads of nucleotide sequences, wherein the nucleic acid sequencing comprises high-througput sequencing; b) comparing the random reads from step a) with a nucleotide sequence of a biological component used in the process for producing the composition whereby a match between a random read and a nucleotide sequence of a biological component identifies a nucleic acid impurity; c) determining the average number of reads per parvoviral vector; and d) determining the number of reads per nucleotide of the overrepresented nucleic acid impurity, wherein a nucleic acid impurity is identified as an overrepresented impurity when the distribution of reads is not random and the overrepresented impurity comprises 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20 or 50 times the average number of reads of the biological component, or when the number of reads per nucleotide of a nucleic acid impurity is at least 0.001, 0.01, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 2.0, 3.0, 5.0, 7.0 or 10% of the average number of reads per parvoviral vector. a) subjecting the composition to nucleic acid sequencing to obtain random reads of nucleotide sequences, wherein the nucleic acid sequencing comprises high-througput sequencing; b) comparing the random reads from step a) with a nucleotide sequence of a biological component used in the process for producing the composition whereby a match between a random read and a nucleotide sequence of a biological component identifies a nucleic acid impurity; c) determining the average number of reads per parvoviral vector; and d) determining the number of reads per nucleotide of the overrepresented nucleic acid impurity, wherein a nucleic acid impurity is identified as an overrepresented impurity when the distribution of reads is not random and the overrepresented impurity comprises 2, 3, 4, 5, 6, 7, 8, 9, 10, 15, 20 or 50 times the average number of reads of the biological component, or when the number of reads per nucleotide of a nucleic acid impurity is at least 0.001, 0.01, 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1.0, 2.0, 3.0, 5.0, 7.0 or 10% of the average number of reads per parvoviral vector.
A pipe-laying vessel including a pipe-laying tower extending upwardly from the vessel, the vessel comprising: - at least two clamping assemblies for clamping a pipeline, the clamping assemblies being mounted along the length of the tower, and - at least three separate workstations spaced apart along the length of the tower , - at least one workstation which is • mounted on the tower below a lowermost clamping assembly , and • a flexible product attaching station for attaching a flexible conduit alongside the pipeline. - at least two clamping assemblies for clamping a pipeline, the clamping assemblies being mounted along the length of the tower, and - at least three separate workstations spaced apart along the length of the tower , - at least one workstation which is • mounted on the tower below a lowermost clamping assembly , and • a flexible product attaching station for attaching a flexible conduit alongside the pipeline. • mounted on the tower below a lowermost clamping assembly , and • a flexible product attaching station for attaching a flexible conduit alongside the pipeline.
A method of forming a hydrolysis resistant aqueous emulsion comprising a hydrolyzable silicon containing compound, said method comprising the steps of: A. forming a seed emulsion comprising; an emulsifier, water, and a first oil phase; and B. adding a second oil phase comprising a hydrolyzable silicon containing compound to the seed emulsion; wherein a weight ratio of the second oil phase comprising a hydrolyzable silicon containing compound to the first oil phase of the seed emulsion is from 0.5 to 50, wherein a total weight of the two oil phases in the emulsion is at least 60 weight percent and wherein a ratio of a molar concentration of water to a total molar concentration of the hydrolyzable silicon containing compound in the aqueous emulsion is less than 2. A. forming a seed emulsion comprising; an emulsifier, water, and a first oil phase; and an emulsifier, water, and a first oil phase; and B. adding a second oil phase comprising a hydrolyzable silicon containing compound to the seed emulsion;
A method for obtaining an aqueous extract a Dunaliella salina microalgae in which said microalgae is cultivated in the absence of light in a culture medium comprising a yeast extract, sugar and salt according to the following steps: a) solubilising a yeast extract in water; b) adding glucose to the mixture obtained in a); c) adding Dead Sea salt; d) after total solubilisation of the salt in the mixture obtained in b), the culture medium thus obtained has a pH of between 5 and 8, and the microalgae Dunaliella salina is added thereto; e) moderately stirring the mixture obtained in d), in darkness and at room temperature, for a period of at least 12 hours, in order to allow the fermentation of the microalgae Dunaliella salina; f) grinding and then filtering the fermented Dunaliella salina mixture obtained in e) in order to separate the soluble and insoluble materials; g) recovering a soluble aqueous raw extract to which Dead Sea salt or a preservative such as sodium benzoate is added; h) carrying out sterilising filtration with a porosity threshold of less than or equal to 0.2 μm; and i) obtaining a fermented aqueous extract of Dunaliella salina in which the pH is between 3.5 and 4.5. a) solubilising a yeast extract in water; b) adding glucose to the mixture obtained in a); c) adding Dead Sea salt; d) after total solubilisation of the salt in the mixture obtained in b), the culture medium thus obtained has a pH of between 5 and 8, and the microalgae Dunaliella salina is added thereto; e) moderately stirring the mixture obtained in d), in darkness and at room temperature, for a period of at least 12 hours, in order to allow the fermentation of the microalgae Dunaliella salina; f) grinding and then filtering the fermented Dunaliella salina mixture obtained in e) in order to separate the soluble and insoluble materials; g) recovering a soluble aqueous raw extract to which Dead Sea salt or a preservative such as sodium benzoate is added; h) carrying out sterilising filtration with a porosity threshold of less than or equal to 0.2 μm; and i) obtaining a fermented aqueous extract of Dunaliella salina in which the pH is between 3.5 and 4.5.
A cosmetic non-therapeutic method of reducing fat mass on lean mass ratio in a subject in need thereof, comprising orally administering to the subject an effective amount of a ClpB protein or an effective amount of a bacterium that expresses the ClpB protein; wherein the ClpB protein comprises an amino acid sequence having at least 80% of identity with SEQ ID NO:1.
An organic electroluminescent device, comprising m kinds of light-emitting units having different light-emitting wavelengths, wherein the light-emitting units are organic light-emitting diodes , wherein the organic light-emitting diodes comprise single-colored organic light-emitting diodes and/or white-light organic light-emitting diodes provided with optical filters ; the m kinds of the organic light-emitting diodes have a microcavity structure; a microcavity optical length L i of the organic light-emitting diode having the microcavity structure and a light-emitting wavelength λ i , of the corresponding light-emitting unit meet the following relation formula: L i = n i λ i where n i ≥2, n i ; is a positive integer, and the n i corresponding to at least one of the m kinds of light-emitting units having different light-emitting wavelengths λ i is larger than or equal to 3; m≥i≥1, i and m are positive integers, characterized in that , m is 3, λ 1 > λ 2 > λ 3 , and n 2 > n 1 , n 2 > n 3 . the m kinds of the organic light-emitting diodes have a microcavity structure; a microcavity optical length L i of the organic light-emitting diode having the microcavity structure and a light-emitting wavelength λ i , of the corresponding light-emitting unit meet the following relation formula: L i = n i λ i where n i ≥2, n i ; is a positive integer, and the n i corresponding to at least one of the m kinds of light-emitting units having different light-emitting wavelengths λ i is larger than or equal to 3; m≥i≥1, i and m are positive integers, characterized in that , m is 3, λ 1 > λ 2 > λ 3 , and n 2 > n 1 , n 2 > n 3 .
A method for manufacturing a water-soluble laundry detergent sheet, the method comprising, consisting essentially of or consisting of the steps: (i) providing an aqueous liquid, preferably homogenous, composition comprising, consisting essentially of or consisting of the following components: (a) at least one acrylamide polymer, (b) at least one surfactant, (c) at least one water-soluble polymer, (d) optionally at least one washing booster selected from the group consisting of enzymes and polyalkyleneimines, (e) optionally at least one perfume component, and (f) optionally at least one adjunct detergent ingredient; (ii) applying the composition of step (i) onto a surface such that it forms a layer on said surface; (iii) drying said layer to obtain a laundry detergent sheet; and (iv) optionally cutting the laundry detergent sheet into pieces of a desired shape and size; and (v) optionally packaging one or more laundry detergent sheets obtained in step (iv), wherein the at least one acrylamide polymer is selected from the group consisting of 2-propenamide polymer with N,N,N-trimethyl-3-[(1-oxo-2-propenyl)amino]-1-propanaminium chloride; and is contained in the composition in amounts of from 0.1 to 20 wt.-%, preferably in 0.1 to 10 wt.-%, based on the total weight of the composition. (i) providing an aqueous liquid, preferably homogenous, composition comprising, consisting essentially of or consisting of the following components: (a) at least one acrylamide polymer, (b) at least one surfactant, (c) at least one water-soluble polymer, (d) optionally at least one washing booster selected from the group consisting of enzymes and polyalkyleneimines, (e) optionally at least one perfume component, and (f) optionally at least one adjunct detergent ingredient; (a) at least one acrylamide polymer, (b) at least one surfactant, (c) at least one water-soluble polymer, (d) optionally at least one washing booster selected from the group consisting of enzymes and polyalkyleneimines, (e) optionally at least one perfume component, and (f) optionally at least one adjunct detergent ingredient; (ii) applying the composition of step (i) onto a surface such that it forms a layer on said surface; (iii) drying said layer to obtain a laundry detergent sheet; and (iv) optionally cutting the laundry detergent sheet into pieces of a desired shape and size; and (v) optionally packaging one or more laundry detergent sheets obtained in step (iv), is selected from the group consisting of 2-propenamide polymer with N,N,N-trimethyl-3-[(1-oxo-2-propenyl)amino]-1-propanaminium chloride; and is contained in the composition in amounts of from 0.1 to 20 wt.-%, preferably in 0.1 to 10 wt.-%, based on the total weight of the composition.
Harvesting device , which is intended for arranging on a vehicle , for fruit-bearing plants, in particular for grapes on vines planted in rows, wherein the harvesting device is designed to be movable along the fruit-bearing plants in the direction of travel and working direction and has a plurality of shaking rods extending parallel to the direction of travel and arranged spaced apart one above another, wherein the shaking rods are in each case connected at a first end for conjoint rotation to a drive element , which, in turn, is rotatably mounted about its longitudinal axis in the harvesting device and extends vertically along a plurality of shaking rods , wherein the drive element is drivable in a rotational movement oscillating over a certain angular range about its longitudinal axis , as a result of which the shaking rods , which are connected to the drive element for conjoint rotation, perform a reciprocating shaking movement , which is directed at the plants, in a horizontal plane and transversely to its longitudinal extent, characterized in that the connection for conjoint rotation between the drive element and the first end of the respective shaking rod is designed as a releasable locking mechanism, which is remotely actuable by means of hydraulically, electromechanically or electromagnetically driven actuators , of a rotatable mounting of the shaking rod about the longitudinal axis of the drive element , the shaking rod being fixable relative to the drive element .
A device comprising: circuitry configured to select a transmission weight for each of a plurality of signal points, by which the respective signal point is to be multiplied, based on an index of a power layer, from among a plurality of quasi-statically selected transmission weights; multiply signals corresponding to each of the plurality of signal points by the transmission weight selected for the respective signal point; multiplex the multiplied signals corresponding to each of the plurality of signal points on a same frequency and time resource; and modify a selection rule for selecting the transmission weight, by which each of the plurality of signal points is to be multiplied, by switching the selection rule, wherein a selection rule of the transmission weight, by which a signal point with a power level less than a predetermined value is to be multiplied, is switched. select a transmission weight for each of a plurality of signal points, by which the respective signal point is to be multiplied, based on an index of a power layer, from among a plurality of quasi-statically selected transmission weights; multiply signals corresponding to each of the plurality of signal points by the transmission weight selected for the respective signal point; multiplex the multiplied signals corresponding to each of the plurality of signal points on a same frequency and time resource; and modify a selection rule for selecting the transmission weight, by which each of the plurality of signal points is to be multiplied, by switching the selection rule, wherein a selection rule of the transmission weight, by which a signal point with a power level less than a predetermined value is to be multiplied, is switched.
A non-phospholipid paucilamellar liposome comprising a cavity having encapsulated therein hyaluronic acid, wherein said liposome is about 50 to 950 nm in size, wherein the hyaluronic acid is cross-linked.
An electrode catalyst layer configured to be bonded to a polymer electrolyte membrane in a polymer electrolyte fuel cell, the electrode catalyst layer comprising: a catalyst material ; a conductive carrier that supports the catalyst material; a polymer electrolyte containing a sulfonate group; and a fibrous material , wherein the electrode catalyst layer includes a first surface (S1) configured to be in contact with the polymer electrolyte membrane and a second surface (S2) facing away from the first surface, and wherein a value is obtained by dividing a peak intensity of HSO 4 (m/z97) by a peak intensity of carbon (m/z12), when the electrode catalyst layer is analyzed using time-of-flight secondary ion mass spectrometry (TOF-SIMS) at each of a plurality of positions in a thickness direction of the electrode catalyst layer from the first surface to the second surface, and a rate of change of the value with respect to a thickness of the electrode catalyst layer is -0.0080 or less, and wherein the analysis using the time-of-flight secondary ion mass spectrometry (TOF-SIMS) is conducted as explained in the description. a catalyst material ; a conductive carrier that supports the catalyst material; a polymer electrolyte containing a sulfonate group; and a fibrous material , wherein the electrode catalyst layer includes a first surface (S1) configured to be in contact with the polymer electrolyte membrane and a second surface (S2) facing away from the first surface, and wherein a value is obtained by dividing a peak intensity of HSO 4 (m/z97) by a peak intensity of carbon (m/z12), when the electrode catalyst layer is analyzed using time-of-flight secondary ion mass spectrometry (TOF-SIMS) at each of a plurality of positions in a thickness direction of the electrode catalyst layer from the first surface to the second surface, and a rate of change of the value with respect to a thickness of the electrode catalyst layer is -0.0080 or less, and wherein the analysis using the time-of-flight secondary ion mass spectrometry (TOF-SIMS) is conducted as explained in the description.
A method of wellbore operations comprising: a. forming perforations in a formation that surrounds the wellbore by detonating shaped charges that are strategically disposed in a perforating gun so that the resulting perforations are axially consolidated, the resulting perforations spanning an axial length of the wellbore that ranges up to 1.5 feet (0.46 m); and b. generating a fracture in the wellbore that is in communication with the perforations and that is substantially perpendicular with an axis (A x ) of the wellbore . a. forming perforations in a formation that surrounds the wellbore by detonating shaped charges that are strategically disposed in a perforating gun so that the resulting perforations are axially consolidated, the resulting perforations spanning an axial length of the wellbore that ranges up to 1.5 feet (0.46 m); and b. generating a fracture in the wellbore that is in communication with the perforations and that is substantially perpendicular with an axis (A x ) of the wellbore .
A device for subjecting a substance to heat treatment, the device comprising: . an enclosure having a lining of refractory material; . a screw mounted to rotate inside the lining about an axis of rotation in order to move the substance between an inlet to the lining and an outlet from the lining, the screw also forming heater means for applying heat treatment to the substance when the screw is electrically powered; the device being characterized in that it includes at least one heater element for heating the lining in service, the heater element being arranged within at least one of the walls of the lining, the lining being arranged inside the enclosure . . an enclosure having a lining of refractory material; . a screw mounted to rotate inside the lining about an axis of rotation in order to move the substance between an inlet to the lining and an outlet from the lining, the screw also forming heater means for applying heat treatment to the substance when the screw is electrically powered;
A vehicle parking payment system , comprising: a digital license plate attached to an exterior of a vehicle , the digital license plate having a display , and being wirelessly connectable to send and receive data; wherein the digital license plate comprises a processing device programmed to: detect parking of the vehicle; wirelessly search for information or data provided by at least one of a parking related facility , meter , and fine system ; request authorization to pay parking related payments to a payment authority; send the authorization to pay parking related payments to a payment authority , with the authorization at least partially incorporating information stored in the digital license plate; and present on the display a visual indicator of authorized parking of the vehicle. a digital license plate attached to an exterior of a vehicle , the digital license plate having a display , and being wirelessly connectable to send and receive data; wherein the digital license plate comprises a processing device programmed to: detect parking of the vehicle; wirelessly search for information or data provided by at least one of a parking related facility , meter , and fine system ; request authorization to pay parking related payments to a payment authority; send the authorization to pay parking related payments to a payment authority , with the authorization at least partially incorporating information stored in the digital license plate; and present on the display a visual indicator of authorized parking of the vehicle. detect parking of the vehicle; wirelessly search for information or data provided by at least one of a parking related facility , meter , and fine system ; request authorization to pay parking related payments to a payment authority; send the authorization to pay parking related payments to a payment authority , with the authorization at least partially incorporating information stored in the digital license plate; and present on the display a visual indicator of authorized parking of the vehicle.
Offshore machining device for rock and sand formations using machining tools such as mills, saws, drills and the like, with a geared motor comprising a drive, a transmission coupled to the drive, and at least one multipart housing for accommodating the drive and transmission, the transmission having at least one shaft, in particular driven shaft , which leads outwards through the housing and to which the machining tool can be attached outside the housing , the transmission motor being fitted with a housing encapsulation, configured to be watertight, for underwater operation, and the housing parts being sealed off along their joining faces by sealing means, and the faces, in particular shafts , which rotate on the drive side and driven side of the housing being sealed off from the housing by annular seals , which can be placed under pressure by way of an upstream chamber , which in each case connects to the face of the annular seal remote from the shaft, the upstream chamber being adjustable, by supplying pressure medium, to a pressure which compensates pressure differences with respect to the water pressure outside the housing as a function of the prescribed operating depth, characterised in that the offshore machining device comprises a pressure medium supply and a pressurised air source, the upstream chamber being fed, via the pressure medium supply line, with pressure medium from the pressurised air source provided outside the geared motor, in such a way that variable, dynamic pressure adjustment is made possible from the outside by supplying pressure medium to the upstream chamber or to the transmission interior in a corresponding manner in adaptation to different usage depths.
A high temperature superconducting, HTS, current lead comprising: an HTS cable comprising a plurality of HTS tapes ; a braided sleeve around the HTS cable; a stabiliser material impregnating the HTS cable and the braided sleeve , the stabiliser material having a melting point above 290K and below a thermal degradation temperature of the HTS tapes ; characterized by a terminal block at each end of the HTS cable, each terminal block being electrically connected to the HTS tape, and being configured for electrical connection to external components, wherein the HTS cable is bent and the terminal blocks are at an angle to each other. an HTS cable comprising a plurality of HTS tapes ; a braided sleeve around the HTS cable; a stabiliser material impregnating the HTS cable and the braided sleeve , the stabiliser material having a melting point above 290K and below a thermal degradation temperature of the HTS tapes ; characterized by a terminal block at each end of the HTS cable, each terminal block being electrically connected to the HTS tape, and being configured for electrical connection to external components, wherein the HTS cable is bent and the terminal blocks are at an angle to each other.