mhurhangee/patent-ind-claim-en huggingface dataset:
An ex-vivo method of modifying a genomic sequence within a cell comprising the steps of: introducing into said cell a single-stranded chemically modified oligonucleotide, wherein said modification(s) is one or more backbone modification(s), wherein said oligonucleotide comprises an editing site that is substantially complementary to a target sequence in said genomic sequence, wherein said modifications of said oligonucleotide increase the efficiency, nuclease stability and/or hybrid affinity as compared to unmodified oligonucleotides, wherein said oligonucleotide further comprises one or more sugar modification(s), wherein said one or more sugar modifications are 2' modified sugars , wherein said 2' modifications are 2'-O-methyl, 2'F, or a combination of 2'-O-methyl and 2'F. introducing into said cell a single-stranded chemically modified oligonucleotide, wherein said modification(s) is one or more backbone modification(s), wherein said oligonucleotide comprises an editing site that is substantially complementary to a target sequence in said genomic sequence, wherein said modifications of said oligonucleotide increase the efficiency, nuclease stability and/or hybrid affinity as compared to unmodified oligonucleotides, wherein said oligonucleotide further comprises one or more sugar modification(s), wherein said one or more sugar modifications are 2' modified sugars , wherein said 2' modifications are 2'-O-methyl, 2'F, or a combination of 2'-O-methyl and 2'F.
A dry-expansion tube bundle heat exchanger comprising a shell , a front end head , a rear end head , a first and a second mouth for inlet of a shell-side secondary circulating fluid and a single secondary fluid outlet mouth , said tube bundle comprising at least a first refrigerating circuit internal of the shell , characterised in said first and respectively said second inlet mouth having respective axes (B1, B2) that are orientated towards the front end head and respectively towards the rear end head .
A handheld device for withdrawing bodily fluid from a subject, the device comprising: a housing having an opening ; a skin-piercing assembly positioned at least partially within the housing and having a skin-piercing feature configured to pierce the skin of the subject; an actuator coupled to the skin-piercing assembly , wherein the actuator is movable relative to the housing , and wherein movement of the actuator toward the opening drives the skin-piercing feature toward the opening ; a biasing member coupled to the skin-piercing assembly , wherein the biasing member is configured to drive the skin-piercing assembly away from the opening , and wherein movement of the skin-piercing assembly away from the opening draws a vacuum within at least a portion of the housing ; and a flexible membrane coupled to the housing and covering at least a portion of the opening , wherein the membrane is configured to be drawn at least partially through the opening when the vacuum is drawn. a housing having an opening ; a skin-piercing assembly positioned at least partially within the housing and having a skin-piercing feature configured to pierce the skin of the subject; an actuator coupled to the skin-piercing assembly , wherein the actuator is movable relative to the housing , and wherein movement of the actuator toward the opening drives the skin-piercing feature toward the opening ; a biasing member coupled to the skin-piercing assembly , wherein the biasing member is configured to drive the skin-piercing assembly away from the opening , and wherein movement of the skin-piercing assembly away from the opening draws a vacuum within at least a portion of the housing ; and a flexible membrane coupled to the housing and covering at least a portion of the opening , wherein the membrane is configured to be drawn at least partially through the opening when the vacuum is drawn.
A fan blade of a turbomachine comprising a composite material structure comprising a foot configured to be inserted in a cavity of a fan disc, a vane adapted to extend in an air flow and a stilt extending between the foot and the vane ; wherein the composite material structure has a pressure face , a suction face and a total thickness (E) at the stilt , the total thickness (E) being measured between the pressure face and the suction face in the stilt portion in a plane normal to a stacking axis (Y) of the blade; wherein the composite material structure is obtained by three-dimensional weaving of weft strands and warp strands the fan blade being characterised in that the composite material structure has, within the root and/or the stilt , a first layer comprising the pressure face and having a first thickness (E1) of between 10% and 25% of the total thickness (E), a second layer comprising the suction face and having a second thickness (E2) of between 10% and 25% of the total thickness (E), and a central layer extending between the first layer and the second layer , and in that an entanglement of the warp strands in the first and second layers is greater than an entanglement of the warp strands in the central layer . wherein the composite material structure has a pressure face , a suction face and a total thickness (E) at the stilt , the total thickness (E) being measured between the pressure face and the suction face in the stilt portion in a plane normal to a stacking axis (Y) of the blade; wherein the composite material structure is obtained by three-dimensional weaving of weft strands and warp strands
A method for controlling a vapour compression system , the vapour compression system comprising a compressor unit , a heat rejecting heat exchanger , an ejector , a receiver , at least one expansion device and at least one evaporator arranged in a refrigerant path, the vapour compression system further comprising a liquid separating device arranged in a suction line of the vapour compression system and a liquid level sensor arranged in the liquid separating device , the liquid separating device comprising a gaseous outlet connected to the inlet of the compressor unit and a liquid outlet connected to a secondary inlet of the ejector , the method comprising the step of: - monitoring a liquid level in the liquid separating device by means of the liquid level sensor , characterized in that the method further comprises the step of: - in the case that the liquid level in the liquid separating device is above a predefined threshold level, adjusting a control parameter of the vapour compression system in order to decrease a flow rate of liquid refrigerant from the evaporator(s) to the liquid separating device by, for at least some of the evaporator(s) , selecting a positive setpoint for a superheat value and/or reducing a maximum allowable opening degree of the expansion device(s), thereby preventing said evaporator(s) from being operated in a flooded state. - monitoring a liquid level in the liquid separating device by means of the liquid level sensor , - in the case that the liquid level in the liquid separating device is above a predefined threshold level, adjusting a control parameter of the vapour compression system in order to decrease a flow rate of liquid refrigerant from the evaporator(s) to the liquid separating device by, for at least some of the evaporator(s) , selecting a positive setpoint for a superheat value and/or reducing a maximum allowable opening degree of the expansion device(s), thereby preventing said evaporator(s) from being operated in a flooded state.
An information processing device comprising: a data processing unit configured to acquire a transport stream, TS, file storing data to be processed, acquire video attribute information stored in a Program Map Table, PMT, in PSI/SI data inside the transport stream, TS, file, and execute format conversion applying the acquired video attribute information, wherein the video attribute information is video attribute information in video stream units stored in the transport stream, TS, file, and includes various attribute information related to individual video streams and comprises information enabling identification of whether each video stream is high dynamic range, HDR, video or standard dynamic range, SDR, video, the data processing unit is configured to execute format conversion for converting the transport stream, TS, file to an MP4 file, and to execute conversion control depending on whether the video stream to be subjected to the format conversion is HDR video or SDR video; wherein the data processing unit is further configured to execute a process of acquiring the video attribute information in video stream units stored in the Program Map Table, PMT, in PSI/SI data inside the transport stream, TS, file, and storing the acquired video attribute information in a metadata storage area of the MP4 file based on the conversion control. a data processing unit configured to acquire a transport stream, TS, file storing data to be processed, acquire video attribute information stored in a Program Map Table, PMT, in PSI/SI data inside the transport stream, TS, file, and execute format conversion applying the acquired video attribute information, wherein the video attribute information is video attribute information in video stream units stored in the transport stream, TS, file, and includes various attribute information related to individual video streams and comprises information enabling identification of whether each video stream is high dynamic range, HDR, video or standard dynamic range, SDR, video, the data processing unit is configured to execute format conversion for converting the transport stream, TS, file to an MP4 file, and to execute conversion control depending on whether the video stream to be subjected to the format conversion is HDR video or SDR video; wherein the data processing unit is further configured to execute a process of acquiring the video attribute information in video stream units stored in the Program Map Table, PMT, in PSI/SI data inside the transport stream, TS, file, and storing the acquired video attribute information in a metadata storage area of the MP4 file based on the conversion control.
Stopper rod for controlling the flow of molten metal and for supplying gas during casting of molten metal, said stopper rod comprising: 1.1 a rod-shaped stopper body , said rod-shaped stopper body 1.1.1 extending along a central longitudinal axis (L) from a first end to a second end , 1.1.2 said rod-shaped stopper body defining a nose adjacent to said second end , wherein 1.1.3 said nose provides an exterior surface; 1.2 a chamber , said chamber 1.2.1 extending along said central longitudinal axis (L) into said stopper body from said first end towards said second end and ending at a distance from said second end ; characterized by 1.3 a channel , said channel 1.3.1 being provided on said exterior surface of said nose , and 1.3.2 running around said longitudinal axis (L); 1.4 gas supply means , said gas supply means 1.4.1 leading from said chamber and through said rod-shaped stopper body into said channel . 1.1 a rod-shaped stopper body , said rod-shaped stopper body 1.1.1 extending along a central longitudinal axis (L) from a first end to a second end , 1.1.2 said rod-shaped stopper body defining a nose adjacent to said second end , wherein 1.1.3 said nose provides an exterior surface; 1.1.1 extending along a central longitudinal axis (L) from a first end to a second end , 1.1.2 said rod-shaped stopper body defining a nose adjacent to said second end , wherein 1.1.3 said nose provides an exterior surface; 1.2 a chamber , said chamber 1.2.1 extending along said central longitudinal axis (L) into said stopper body from said first end towards said second end and ending at a distance from said second end ; characterized by 1.3 a channel , said channel 1.3.1 being provided on said exterior surface of said nose , and 1.3.2 running around said longitudinal axis (L); 1.3.1 being provided on said exterior surface of said nose , and 1.3.2 running around said longitudinal axis (L); 1.4 gas supply means , said gas supply means 1.4.1 leading from said chamber and through said rod-shaped stopper body into said channel .
A wireless power transfer apparatus comprising: an AC input port configured to be coupled to an AC power source ; a converter circuit having a first port coupled to the AC input port ; an energy storage circuit coupled to the converter circuit at a second port of the converter circuit ; a resonant circuit coupled to the converter circuit at the first port of the converter circuit and configured to inductively transfer power to an external device; and a control circuit configured to control the converter circuit responsive to a signal indicative of a state of the external device. an AC input port configured to be coupled to an AC power source ; a converter circuit having a first port coupled to the AC input port ; an energy storage circuit coupled to the converter circuit at a second port of the converter circuit ; a resonant circuit coupled to the converter circuit at the first port of the converter circuit and configured to inductively transfer power to an external device; and a control circuit configured to control the converter circuit responsive to a signal indicative of a state of the external device.
A method of forming an airfoil, comprising: forming a hybrid skin core , a tip flag core , and a trailing edge core , wherein the hybrid skin core , tip flag core , and trailing edge core are connected to form a contiguous first core portion; forming a leading edge core and a serpentine core ; assembling the first core portion, the leading edge core , and the serpentine core together to form an airfoil core ; and forming an airfoil around the airfoil core ; wherein: the hybrid skin core , tip flag core , trailing edge core , leading edge core , and serpentine core are injection molded; and the tip flag core , trailing edge core and hybrid skin core are formed concurrently in a first die. forming a hybrid skin core , a tip flag core , and a trailing edge core , wherein the hybrid skin core , tip flag core , and trailing edge core are connected to form a contiguous first core portion; forming a leading edge core and a serpentine core ; assembling the first core portion, the leading edge core , and the serpentine core together to form an airfoil core ; and forming an airfoil around the airfoil core ; wherein: the hybrid skin core , tip flag core , trailing edge core , leading edge core , and serpentine core are injection molded; and the tip flag core , trailing edge core and hybrid skin core are formed concurrently in a first die. the hybrid skin core , tip flag core , trailing edge core , leading edge core , and serpentine core are injection molded; and the tip flag core , trailing edge core and hybrid skin core are formed concurrently in a first die.
A method of wireless communication at a relay user equipment, UE, comprising: receiving , on a downlink channel from a network entity , at least one indication including resource allocation information for at least a remote UE , wherein the resource allocation information corresponds to downlink control information, DCI, including a resource allocation for the remote UE at a first time value representing a subframe slot plus a first time variable associated with the resource allocation; wherein the first time variable corresponds to at least one of a fixed value or a radio resource control, RRC, configured value; transmitting , on a sidelink channel to the remote UE, the resource allocation information for the remote UE, wherein transmitting the resource allocation information to the remote UE includes transmitting the DCI as a medium access control, MAC, control element, CE, as part of a sidelink shared channel, SL-SCH, data, and wherein the DCI is transmitted at a second time value representing the subframe slot plus a second time variable less than the first time variable. receiving , on a downlink channel from a network entity , at least one indication including resource allocation information for at least a remote UE , wherein the resource allocation information corresponds to downlink control information, DCI, including a resource allocation for the remote UE at a first time value representing a subframe slot plus a first time variable associated with the resource allocation; wherein the first time variable corresponds to at least one of a fixed value or a radio resource control, RRC, configured value; transmitting , on a sidelink channel to the remote UE, the resource allocation information for the remote UE, wherein transmitting the resource allocation information to the remote UE includes transmitting the DCI as a medium access control, MAC, control element, CE, as part of a sidelink shared channel, SL-SCH, data, and wherein the DCI is transmitted at a second time value representing the subframe slot plus a second time variable less than the first time variable.
Valve for reciprocating compressors, the valve comprising: - a valve seat with first gas flow passages extending through said valve seat ; - a valve guard having second gas flow passages extending through said valve guard ; - at least one shutter ring arranged between said valve guard and said valve seat , the shutter ring being configured to move between a closed position in which the passage of fluid is prevented and an open position in which the passage of fluid is allowed, wherein said at least one shutter ring is resiliently biased by resilient members against the valve seat to close said first gas flow passages , wherein the valve seat and the valve guard are relatively movable to define a variable gap or lift for the shutter ring and characterized in that the valve further comprises an actuator (32, 2. 34, 42, 43) to adjust the relative position of the valve seat and the valve guard . - a valve seat with first gas flow passages extending through said valve seat ; - a valve guard having second gas flow passages extending through said valve guard ; - at least one shutter ring arranged between said valve guard and said valve seat , the shutter ring being configured to move between a closed position in which the passage of fluid is prevented and an open position in which the passage of fluid is allowed,
Resistance welding method in which - a metallic conductor is welded to a metallic terminal , wherein - the metallic terminal is placed with a first surface onto a first electrode , - the metallic conductor is placed on a bottom of a recess , wherein the recess is arranged in a second surface opposite the first surface, characterized in that - at least two side sliders are placed on the second surface lateral of the recess wherein a distance is formed between an edge of the recess and a surface of the side sliders facing the conductor , and wherein the side slides are moved in parallel to the second surface over the second surface into the region of the edge of the recess , a second electrode is moved in the direction of the first electrode onto the conductor , and - the conductor is welded to the terminal in the region of the recess by means of a current flowing between the first and the second electrode , wherein the side walls of the recess form a boundary for the material of the conductor which is plasticized by the welding operation, and the side sliders do not come into contact with the plasticized material. - a metallic conductor is welded to a metallic terminal , wherein - the metallic terminal is placed with a first surface onto a first electrode , - the metallic conductor is placed on a bottom of a recess , wherein the recess is arranged in a second surface opposite the first surface, characterized in that - at least two side sliders are placed on the second surface lateral of the recess wherein a distance is formed between an edge of the recess and a surface of the side sliders facing the conductor , and wherein the side slides are moved in parallel to the second surface over the second surface into the region of the edge of the recess , a second electrode is moved in the direction of the first electrode onto the conductor , and - the conductor is welded to the terminal in the region of the recess by means of a current flowing between the first and the second electrode , wherein the side walls of the recess form a boundary for the material of the conductor which is plasticized by the welding operation, and the side sliders do not come into contact with the plasticized material.
An ultrasonic inspection phantom (101;103) comprising a hydrogel: the hydrogel comprising water, a water soluble polymer, and characterised in that the hydrogel further comprises a water-swellable laminate clay mineral.
Personal electronic delivery unit, comprising: - a primary housing comprising an energy source and having a first end with an air inlet and a second end with a primary connector configured for connecting to a secondary housing configured for holding a cartridge with a delivery fluid and having an outlet or mouth piece ; - a fluid path substantially extending between the air inlet and the outlet or mouth piece ; - a heater element (30 that is provided in, at or close to the fluid path configured for heating the delivery fluid such that at least a part of a delivery fluid atomises and/or vaporises in the fluid path, wherein the heater element is in use connected to the energy source configured for providing energy to the heater element , and wherein the heater element is provided in and/or attached to the primary housing ; and - a delivery fluid transfer element that is configured for transferring delivery fluid from the cartridge to the fluid path; and wherein the heater comprises a conductor and a porous ceramic layer that is configured to control the atomizing and/or vaporizing, characterised in that the ceramic layer is provided on or at the conductor with plasma electrolytic oxidation. - a primary housing comprising an energy source and having a first end with an air inlet and a second end with a primary connector configured for connecting to a secondary housing configured for holding a cartridge with a delivery fluid and having an outlet or mouth piece ; - a fluid path substantially extending between the air inlet and the outlet or mouth piece ; - a heater element (30 that is provided in, at or close to the fluid path configured for heating the delivery fluid such that at least a part of a delivery fluid atomises and/or vaporises in the fluid path, wherein the heater element is in use connected to the energy source configured for providing energy to the heater element , and wherein the heater element is provided in and/or attached to the primary housing ; and - a delivery fluid transfer element that is configured for transferring delivery fluid from the cartridge to the fluid path; and