mhurhangee/patent-ind-claim-en huggingface dataset:
Composition comprising an alpha 7 nicotinic acetylcholine receptor agonist for use in treatment of cognitive impairments, psychotic and/or neurodegenerative disorders in a selected patient population, wherein the patient population is selected on the basis of having at least one indicative SNP of the human acetylcholine receptor subunit alpha-5 ( CHRNA5) gene or the human acetylcholine receptor subunit alpha-3 ( CHRNA3) gene, wherein any of a homozygous genotype of rs55853698-T/T or a SNP forming a haplotype with said SNP, are indicative SNPs of the CHRNA5 gene, wherein any of a homozygous genotype of rs1051730-C/C, a homozygous genotype of rs6495308-C/C, a heterozygous genotype of rs6495308-C/T, or a SNP forming a haplotype with any of said SNPs are indicative SNPs of the CHRNA3 gene, and wherein the alpha 7 nicotinic acetylcholine receptor agonist is (R)-3-(6-p-tolyl-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane in free base form or in acid addition salt form. wherein the patient population is selected on the basis of having at least one indicative SNP of the human acetylcholine receptor subunit alpha-5 ( CHRNA5) gene or the human acetylcholine receptor subunit alpha-3 ( CHRNA3) gene, wherein any of a homozygous genotype of rs55853698-T/T or a SNP forming a haplotype with said SNP, are indicative SNPs of the CHRNA5 gene, wherein any of a homozygous genotype of rs1051730-C/C, a homozygous genotype of rs6495308-C/C, a heterozygous genotype of rs6495308-C/T, or a SNP forming a haplotype with any of said SNPs are indicative SNPs of the CHRNA3 gene, and wherein the alpha 7 nicotinic acetylcholine receptor agonist is (R)-3-(6-p-tolyl-pyridin-3-yloxy)-1-aza-bicyclo[2.2.2]octane in free base form or in acid addition salt form.
A method, performed by a wireless communication device , for handling paging messages for paging of wireless communication devices in a wireless communication system , wherein the method comprises: receiving (A065), from a radio network node , at a first paging occasion within a paging frame, a first paging message characterised by : a parameter indicating existence of at least one second paging occasion, wherein a first subframe location of the first paging occasion within the paging frame is different from at least one second subframe location of the at least one second paging occasion; monitoring (A095) the at least one second paging occasion, and receiving (A100), at the at least one second paging occasion, the second paging message from the radio network node , wherein at least one of the at least one second paging occasion is located in a radio frame subsequent to the paging frame. receiving (A065), from a radio network node , at a first paging occasion within a paging frame, a first paging message characterised by : a parameter indicating existence of at least one second paging occasion, wherein a first subframe location of the first paging occasion within the paging frame is different from at least one second subframe location of the at least one second paging occasion; monitoring (A095) the at least one second paging occasion, and receiving (A100), at the at least one second paging occasion, the second paging message from the radio network node , wherein at least one of the at least one second paging occasion is located in a radio frame subsequent to the paging frame.
A method performed by at least one processor that implements a first server, the method comprising: obtaining a group identifier of a pair of an unmanned aerial vehicle, UAV, and a controller of the UAV, and a respective subgroup identifier for each of the UAV and the controller; based on requesting a second server to create one or more groups for the pair; provisioning Quality of Service, QoS, for communication of the pair, using the group identifier of the pair and the respective subgroup identifier for each of the UAV and the controller; determining whether a condition of the communication satisfies a pre-defined QoS requirement for the communication of the UAV and the controller; and triggering , based on determining that a condition of the communication does not satisfy the pre-defined QoS requirement, a third server to perform adaptation of the QoS for the UAV and the controller. obtaining a group identifier of a pair of an unmanned aerial vehicle, UAV, and a controller of the UAV, and a respective subgroup identifier for each of the UAV and the controller; based on requesting a second server to create one or more groups for the pair; provisioning Quality of Service, QoS, for communication of the pair, using the group identifier of the pair and the respective subgroup identifier for each of the UAV and the controller; determining whether a condition of the communication satisfies a pre-defined QoS requirement for the communication of the UAV and the controller; and triggering , based on determining that a condition of the communication does not satisfy the pre-defined QoS requirement, a third server to perform adaptation of the QoS for the UAV and the controller.
A method comprising: removing heat from a refrigerant using a high side heat exchanger ; storing the refrigerant using a flash tank ; sending the refrigerant from the flash tank to a tube of an integrated subcooler and accumulator , the integrated subcooler and accumulator comprising a chamber defined by an exterior housing and configured to operate as an accumulator, the tube positioned within the chamber, wherein heat is removed from the refrigerant from the flash tank and in the tube; using the refrigerant from the tube to remove heat from a space proximate a low temperature load ; using the refrigerant from the flash tank to remove heat from a second space proximate a medium temperature load ; sending the refrigerant from the low temperature load into the chamber between the exterior housing and the tube to accumulate liquid refrigerant in the chamber; and sending the refrigerant from the chamber between the exterior housing and the tube to a low temperature compressor , the low temperature compressor configured to compress the refrigerant; and sending the refrigerant from the medium temperature load to a medium temperature compressor through an accumulator. removing heat from a refrigerant using a high side heat exchanger ; storing the refrigerant using a flash tank ; sending the refrigerant from the flash tank to a tube of an integrated subcooler and accumulator , the integrated subcooler and accumulator comprising a chamber defined by an exterior housing and configured to operate as an accumulator, the tube positioned within the chamber, wherein heat is removed from the refrigerant from the flash tank and in the tube; using the refrigerant from the tube to remove heat from a space proximate a low temperature load ; using the refrigerant from the flash tank to remove heat from a second space proximate a medium temperature load ; sending the refrigerant from the low temperature load into the chamber between the exterior housing and the tube to accumulate liquid refrigerant in the chamber; and sending the refrigerant from the chamber between the exterior housing and the tube to a low temperature compressor , the low temperature compressor configured to compress the refrigerant; and sending the refrigerant from the medium temperature load to a medium temperature compressor through an accumulator.
A medical device system for controlling delivery of a ventricular pacing during cardiac resynchronization therapy, comprising: a sensing device configured to sense a cardiac signal and to emit a trigger signal in response to the sensed cardiac signal; a delivery device configured to receive the trigger signal and deliver the ventricular pacing to the patient in response to the emitted trigger signal; and a processor positioned within the sensing device, characterized in that the processor is configured to: identify a fiducial point of the cardiac signal sensed in real-time, set a window comprising a start point positioned a first distance prior to the fiducial point and an endpoint positioned a second distance subsequent to the fiducial point, the second distance being less than the first distance, determine a signal characteristic of the cardiac signal within the window, determine whether a P-wave is detected in response to the signal characteristic, determine a change in slope of the cardiac signal, and determine a local maximum of the cardiac signal as the fiducial point, determine whether a timer associated with an atrio-ventricular interval has expired, and emit a trigger signal via the sensing device, the trigger signal being received by the delivery device and instructing the delivery device to deliver the ventricular pacing timed off of the local maximum in response to the P-wave being detected and not timed off of the local maximum in response to the timer being expired. a sensing device configured to sense a cardiac signal and to emit a trigger signal in response to the sensed cardiac signal; a delivery device configured to receive the trigger signal and deliver the ventricular pacing to the patient in response to the emitted trigger signal; and a processor positioned within the sensing device, characterized in that the processor is configured to: identify a fiducial point of the cardiac signal sensed in real-time, set a window comprising a start point positioned a first distance prior to the fiducial point and an endpoint positioned a second distance subsequent to the fiducial point, the second distance being less than the first distance, determine a signal characteristic of the cardiac signal within the window, determine whether a P-wave is detected in response to the signal characteristic, determine a change in slope of the cardiac signal, and determine a local maximum of the cardiac signal as the fiducial point, determine whether a timer associated with an atrio-ventricular interval has expired, and emit a trigger signal via the sensing device, the trigger signal being received by the delivery device and instructing the delivery device to deliver the ventricular pacing timed off of the local maximum in response to the P-wave being detected and not timed off of the local maximum in response to the timer being expired.
Inner ring for a guide vane ring for fastening to, in particular adjustable, guide vanes of a turbomachine, in particular of a compressor stage or turbine stage of a gas turbine, the inner ring comprising a plurality of guide vane receptacles which are each arranged spaced from each other in the circumferential direction and are in each case designed for receiving a fastening element of a guide vane , the inner ring comprising, between at least two adjacent guide vane receptacles , at least one recess having a wall thickness that is reduced in the radial direction (y) in comparison to a region which adjoins the recess and is outside the recess , the recess comprising, in relation to an axis of rotation of the turbomachine in a functionally installed state of the inner ring in a turbomachine, a greater extension in the axial direction (x) than in the circumferential direction characterized in that at least one recess comprises an hourglass-shaped or hourglass-like shaped peripheral contour , in particular in relation to a projection of the peripheral contour of the recess in a tangential plane of the inner ring. the inner ring comprising a plurality of guide vane receptacles which are each arranged spaced from each other in the circumferential direction and are in each case designed for receiving a fastening element of a guide vane , the inner ring comprising, between at least two adjacent guide vane receptacles , at least one recess having a wall thickness that is reduced in the radial direction (y) in comparison to a region which adjoins the recess and is outside the recess , the recess comprising, in relation to an axis of rotation of the turbomachine in a functionally installed state of the inner ring in a turbomachine, a greater extension in the axial direction (x) than in the circumferential direction characterized in that at least one recess comprises an hourglass-shaped or hourglass-like shaped peripheral contour , in particular in relation to a projection of the peripheral contour of the recess in a tangential plane of the inner ring.
Fire-safety-training device for simulating a liquid fire, having - at least one first burner device , and having - a second burner device which has at least one gas line with multiple exit openings , characterized - in that the gas line of the second burner device is arranged at least partially in a channel which is configured to be filled, in the position of use, with water such that the at least one gas line is situated underwater. - at least one first burner device , and having - a second burner device which has at least one gas line with multiple exit openings , characterized - in that the gas line of the second burner device is arranged at least partially in a channel which is configured to be filled, in the position of use, with water such that the at least one gas line is situated underwater.
Illumination device for illuminating an interior of a motor vehicle , having a first and a second illumination subregion of the illumination device , and having at least one first light source with a first light cone and a second light source with a second light cone , wherein the first and second illumination subregions are embodied as regions of a cover element of the illumination device which immediately adjoin one another and are able to be backlit by the first or second light source , and the light sources are designed to be activated independently of one another and to illuminate the interior , wherein the first light source has a first light main emission direction and the second light source has a second light main emission direction , and having a diffuser element positioned in the beam paths of the light sources , and having a light shading element of the illumination device arranged at least partially on a connecting line between the first light source and the second light source in a manner such that a direct line of sight from the first light source to the second light source is interrupted, wherein the connecting line is located substantially at the height of the first light source and the second light source and connects the light main emission directions , characterized in that the first light source and the second light source have a multiplicity of lightemitting diodes and in that the light shading element is arranged, viewed in the direction of the connecting line , closer to the first light source than to the second light source in a manner such that, if the first light source is activated and the second light source is deactivated, only the first illumination subregion is illuminable by means of the first light cone , and if the second light source is activated, the second illumination subregion and at least partially the first illumination subregion are illuminable by means of the second light cone .
A fluorinated ether compound represented by the following formula : A 1 -O-(R f1 O) m1 -Q 1 -[C(O)N(R 1 )] p1 -R 11 -C[-R 12 -SiR 13 n1 X 1 3-n1 ] 3 wherein A 1 is a C 1-20 perfluoroalkyl group, R f1 is a fluoroalkylene group having no branched structure, m1 is an integer of from 2 to 210, (R f1 O) m1 may be one composed of at least two types of R f1 O, Q 1 is a single bond or a fluoroalkylene group having no branched structure, R 1 is a hydrogen atom or an alkyl group, p1 is 0 or 1, R 11 is a single bond, an alkylene group, an alkylene group having an etheric oxygen atom at its terminal (which is the terminal on the side bonded to C[-R 12 -SiR 13 n1 X 1 3-n1 ] 3 ), an alkylene group with at least two carbon atoms, having an etheric oxygen atom between its carbon-carbon atoms, or an alkylene group with at least two carbon atoms, having an etheric oxygen atom between its carbon-carbon atoms and at its terminal (which is the terminal on the side bonded to C[-R 12 -SiR 13 n1 X 1 3-n1 ] 3 ), R 12 is an alkylene group or an alkylene group with at least two carbon atoms, having an etheric oxygen atom between its carbon-carbon atoms, R 13 is a hydrogen atom or a monovalent hydrocarbon group, X 1 is a hydrolyzable group, n1 is an integer of from 0 to 2, and three [-R 12 -SiR 13 n 1 X 1 3-n1 ] may not be all the same group. A 1 is a C 1-20 perfluoroalkyl group, R f1 is a fluoroalkylene group having no branched structure, m1 is an integer of from 2 to 210, (R f1 O) m1 may be one composed of at least two types of R f1 O, Q 1 is a single bond or a fluoroalkylene group having no branched structure, R 1 is a hydrogen atom or an alkyl group, p1 is 0 or 1, R 11 is a single bond, an alkylene group, an alkylene group having an etheric oxygen atom at its terminal (which is the terminal on the side bonded to C[-R 12 -SiR 13 n1 X 1 3-n1 ] 3 ), an alkylene group with at least two carbon atoms, having an etheric oxygen atom between its carbon-carbon atoms, or an alkylene group with at least two carbon atoms, having an etheric oxygen atom between its carbon-carbon atoms and at its terminal (which is the terminal on the side bonded to C[-R 12 -SiR 13 n1 X 1 3-n1 ] 3 ), R 12 is an alkylene group or an alkylene group with at least two carbon atoms, having an etheric oxygen atom between its carbon-carbon atoms, R 13 is a hydrogen atom or a monovalent hydrocarbon group, X 1 is a hydrolyzable group, n1 is an integer of from 0 to 2, and three [-R 12 -SiR 13 n 1 X 1 3-n1 ] may not be all the same group.
An apparatus comprising: a tilt motor fixed to a base and configured to cause a housing to tilt about a horizontal axis; a pan motor fixed to the base and configured to cause the housing to pan about a vertical axis without affecting the tilt of the housing ; a lift nut configured to traverse upwards from the base and downwards towards the base during operation of the tilt motor ; and a lift arm configured such that traversing of the lift nut up and down applies a force to the lift arm , the force operative to cause the housing to tilt about the horizontal axis; and wherein the lift arm is configured to rotate about the lift nut without causing the lift nut to rotate. a tilt motor fixed to a base and configured to cause a housing to tilt about a horizontal axis; a pan motor fixed to the base and configured to cause the housing to pan about a vertical axis without affecting the tilt of the housing ; a lift nut configured to traverse upwards from the base and downwards towards the base during operation of the tilt motor ; and a lift arm configured such that traversing of the lift nut up and down applies a force to the lift arm , the force operative to cause the housing to tilt about the horizontal axis; and wherein the lift arm is configured to rotate about the lift nut without causing the lift nut to rotate.
A method for producing a high strength coated steel sheet having an improved ductility and an improved formability, the sheet having a yield strength YS of at least 800 MPa, a tensile strength TS of at least 1180 MPa, a total elongation of at least 14% and a hole expansion ratio HER according to the ISO standard 16630:2009 of at least 30%, by heat treating and coating a steel sheet wherein the chemical composition of the steel contains in weight %: 0.15% ≤C ≤ 0.25% 1.2% ≤ Si ≤ 1.8% 2% ≤ Mn ≤ 2.4% 0.1% ≤ Cr ≤ 0.25% Al ≤ 0.5% the remainder being Fe and unavoidable impurities, including less than 0.05% for Ni, less than 0.02% Mo, less than 0.03% Cu, less than 0.007% V, less than 0.0010% B, less than 0.005% S, less than 0.02% P, less than 0.010% N, the Nb content being limited to 0.05% and the Ti content being limited to 0.05%, and wherein the heat treatment and the coating comprises the following steps: - annealing the sheet at an annealing temperature TA higher than Ac3 but less than 1000°C for a time of more than 30 s, - quenching the sheet by cooling it down to a quenching temperature QT between 250°C and 350°C, at a cooling speed sufficient to obtain a structure consisting of martensite and austenite just after quenching, the martensite content being at least 60 % and the austenite content being such that the final structure consists of 3 % to 15% of residual austenite and 85 % to 97% of martensite and bainite without ferrite, the structure comprising at least 65% of martensite, - heating the sheet up to a partitioning temperature PT between 430°C and 480°C and maintaining the sheet at this temperature for a partitioning time Pt between 10 s and 90 s, - hot dip coating the sheet and, - cooling the sheet down to the room temperature. 0.15% ≤C ≤ 0.25% 1.2% ≤ Si ≤ 1.8% 2% ≤ Mn ≤ 2.4% 0.1% ≤ Cr ≤ 0.25% Al ≤ 0.5% - annealing the sheet at an annealing temperature TA higher than Ac3 but less than 1000°C for a time of more than 30 s, - quenching the sheet by cooling it down to a quenching temperature QT between 250°C and 350°C, at a cooling speed sufficient to obtain a structure consisting of martensite and austenite just after quenching, the martensite content being at least 60 % and the austenite content being such that the final structure consists of 3 % to 15% of residual austenite and 85 % to 97% of martensite and bainite without ferrite, the structure comprising at least 65% of martensite, - heating the sheet up to a partitioning temperature PT between 430°C and 480°C and maintaining the sheet at this temperature for a partitioning time Pt between 10 s and 90 s, - hot dip coating the sheet and, - cooling the sheet down to the room temperature.