mhurhangee/patent-ind-claim-en huggingface dataset:
An epitope-tagged antibody comprising an antibody and two epitope tag constructs, the epitope tag constructs comprising alternating spacers and epitope tags, wherein the epitope-tagged antibody comprises 8 epitope tags, wherein each of the epitope tags comprises a sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 4, wherein at least a portion of an amino acid sequence, which amino acid sequence constitutes at least one spacer of the epitope tag construct, is selected from the group consisting of SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, and SEQ ID NO: 14, wherein the two epitope tag constructs are expressed at a C-terminal end of a heavy chain constant region of the antibody, and wherein each epitope tag construct comprises four epitope tags. wherein the epitope-tagged antibody comprises 8 epitope tags, wherein each of the epitope tags comprises a sequence having at least 90% identity to the amino acid sequence of SEQ ID NO: 4, wherein at least a portion of an amino acid sequence, which amino acid sequence constitutes at least one spacer of the epitope tag construct, is selected from the group consisting of SEQ ID NO: 10, SEQ ID NO: 11, SEQ ID NO: 12, SEQ ID NO: 13, and SEQ ID NO: 14, wherein the two epitope tag constructs are expressed at a C-terminal end of a heavy chain constant region of the antibody, and wherein each epitope tag construct comprises four epitope tags.
A virtual machine system that includes a plurality of processors and executes a plurality of virtual machines , each processor being placed in any of: a first state in which the processor operates with a power supply; a second state; and a third state in which the processor is not in operation without any power supply, the virtual machine system comprising an allocation unit (2242; 3501) configured to allocate each virtual machine to any processor that is supplied with power, wherein allocating a virtual machine to a processor in the second state causes the processor to be placed in the first state; and a power supply unit (1911; 3502); in said second state, the processor operates with a power supply lower than in the first state, said power supply unit (1911; 3502) configured to, when the allocation unit (2242; 3501) allocates a virtual machine to a processor that is in the second state and does not have any virtual machine allocated thereto, and at least two processors are in the third state, supply power to at least one and less than all of the processors in the third state so as to cause the at least one and less than all of the processors to be placed in the second state, and maintain a remaining one or more of the processors in the third state, characterized in that the plurality of processors include type 1 processors and type 2 processors having a lower processing capability and a lower power consumption than the type 1 processors , for each virtual machine allocated to either type of processors between the type 1 processors and the type 2 processors , when processing of the virtual machine satisfies a predetermined condition, the allocation unit reallocates the virtual machine satisfying the predetermined condition to one of the other type of processors, when the allocation unit allocates a virtual machine to a type 1 processor that is in the second state and does not have any virtual machine allocated thereto, and at least two type 1 processors are in the third state, the power supply unit supplies power to at least one and less than all of the type 1 processors in the third state so as to cause the at least one and less than all of the type 1 processors to be placed in the second state, and maintains a remaining one or more of the type 1 processors in the third state, and when the allocation unit allocates a virtual machine to a type 2 processor that is in the second state and does not have any virtual machine allocated thereto, and at least two type 2 processors are in the third state, the power supply unit supplies power to at least one and less than all of the type 2 processors in the third state so as to cause the at least one and less than all of the type 2 processors to be placed in the second state, and maintains a remaining one or more of the type 2 processors in the third state.
A thermosetting resin composition comprising: (A) an addition reaction product of a maleimide compound having at least two N-substituted maleimide groups in one molecule (a1) and an amine compound having at least two primary amino groups in one molecule (a2), (B) a thermoplastic elastomer, and (C) a copolymer resin having a structural unit derived from an aromatic vinyl compound and a structural unit derived from a carboxylic acid anhydride, wherein the component (a2) contains a modified siloxane having an amino group at the end thereof. (A) an addition reaction product of a maleimide compound having at least two N-substituted maleimide groups in one molecule (a1) and an amine compound having at least two primary amino groups in one molecule (a2), (B) a thermoplastic elastomer, and (C) a copolymer resin having a structural unit derived from an aromatic vinyl compound and a structural unit derived from a carboxylic acid anhydride,
A method of controlling a wind turbine that is operating according to a control signal causing the wind turbine to be over-rated above the wind turbine's rated power, the method comprising: obtaining one or more signals, or values of variables, that indicate the fatigue lifetime of one or more of the wind turbine's components from turbine sensors ; and applying one or more lifetime usage estimator algorithms to the signals or values to determine measures of the fatigue life consumed by each of the turbine components; calculating, for each of the turbine components, a rate of consumption of fatigue life based on the measures of the fatigue life consumed by each of the turbine components; and characterised by controlling the turbine to reduce the amount of power by which the wind turbine is over-rated based on the rate of consumption of fatigue life for at least one of the turbine components, wherein the reduction of the amount of power by which the wind turbine is over-rated is determined by applying a predetermined function that reduces the over-rating amount in proportion to the rate of consumption of fatigue life for each of the at least one turbine components. obtaining one or more signals, or values of variables, that indicate the fatigue lifetime of one or more of the wind turbine's components from turbine sensors ; and applying one or more lifetime usage estimator algorithms to the signals or values to determine measures of the fatigue life consumed by each of the turbine components; calculating, for each of the turbine components, a rate of consumption of fatigue life based on the measures of the fatigue life consumed by each of the turbine components; and characterised by controlling the turbine to reduce the amount of power by which the wind turbine is over-rated based on the rate of consumption of fatigue life for at least one of the turbine components, wherein the reduction of the amount of power by which the wind turbine is over-rated is determined by applying a predetermined function that reduces the over-rating amount in proportion to the rate of consumption of fatigue life for each of the at least one turbine components.
An autonomous floor-traversing robot , comprising: a wheeled body comprising a chassis and at least one motorized wheel configured to propel the chassis across a floor, the chassis defining an interior compartment disposed beneath a chassis ceiling ; a cover extending across at least a central area of the chassis ceiling ; and a graspable handle connected to the chassis and located outside the cover so as to be accessible from above the robot , the handle arranged to enable lifting of the robot ; characterized in that the chassis ceiling defines a primary drainage channel outside the cover configured to catch liquid from an outer surface of the cover and conduct the liquid away from the central area . a wheeled body comprising a chassis and at least one motorized wheel configured to propel the chassis across a floor, the chassis defining an interior compartment disposed beneath a chassis ceiling ; a cover extending across at least a central area of the chassis ceiling ; and a graspable handle connected to the chassis and located outside the cover so as to be accessible from above the robot , the handle arranged to enable lifting of the robot ; characterized in that the chassis ceiling defines a primary drainage channel outside the cover configured to catch liquid from an outer surface of the cover and conduct the liquid away from the central area .
A kit for sequencing a polynucleotide target, comprising: (a) two amplification primers for amplifying DNA by a polymerase chain reaction process, one that is complementary to a first locus on one strand of the DNA, and a second that is complementary to a different or second locus of the other strand of the DNA, said amplification primers each comprising (i) a 3' target-specific nucleotide sequence and (ii) a 5' non-target-specific universal sequencing tag comprising at least three contiguous non-natural nucleobases capable of complementary binding to a corresponding non-natural nucleobase, wherein at least three contiguous non-natural nucleobases are capable of being replicated during amplification by an amplification polymerase but are not capable of being sequenced by a sequencing polymerase, whereby the portion of (ii) that is 5' to the at least three contiguous non-natural nucleobases cannot be sequenced; and (b) corresponding universal sequencing primers each comprising an oligonucleotide of the sequence comprising the 5' non-target-specific universal sequencing tag of the corresponding amplification primer, wherein the tag comprises at least three contiguous non-natural nucleobase capable of hybridizing to complementary non-natural nucleobases and capable of being replicated during amplification. (a) two amplification primers for amplifying DNA by a polymerase chain reaction process, one that is complementary to a first locus on one strand of the DNA, and a second that is complementary to a different or second locus of the other strand of the DNA, said amplification primers each comprising (i) a 3' target-specific nucleotide sequence and (ii) a 5' non-target-specific universal sequencing tag comprising at least three contiguous non-natural nucleobases capable of complementary binding to a corresponding non-natural nucleobase, wherein at least three contiguous non-natural nucleobases are capable of being replicated during amplification by an amplification polymerase but are not capable of being sequenced by a sequencing polymerase, whereby the portion of (ii) that is 5' to the at least three contiguous non-natural nucleobases cannot be sequenced; and (i) a 3' target-specific nucleotide sequence and (ii) a 5' non-target-specific universal sequencing tag comprising (b) corresponding universal sequencing primers each comprising an oligonucleotide of the sequence comprising the 5' non-target-specific universal sequencing tag of the corresponding amplification primer, wherein the tag comprises at least three contiguous non-natural nucleobase capable of hybridizing to complementary non-natural nucleobases and capable of being replicated during amplification.
A method of fabricating a balloon catheter, comprising: providing an inner tubular member having a distal section , a distal end , and a lumen extending therein; forming a balloon having a working length , a distal neck , and a distal leg , the distal leg having a first segment with a first diameter and first wall thickness and a second segment with a second diameter and second wall thickness , the second diameter being larger than the first diameter and the second wall thickness being thinner than the first wall thickness ; positioning the distal end of the inner tubular member in the balloon , with the first segment of the distal leg disposed proximate the distal section of the inner tubular member and the second segment of the distal leg extending distally beyond the distal end of the inner tubular member ; heating the distal leg of the balloon to bond at least a portion of the first segment to the distal section of the inner tubular member and to reduce the second diameter of the second segment of the distal leg . providing an inner tubular member having a distal section , a distal end , and a lumen extending therein; forming a balloon having a working length , a distal neck , and a distal leg , the distal leg having a first segment with a first diameter and first wall thickness and a second segment with a second diameter and second wall thickness , the second diameter being larger than the first diameter and the second wall thickness being thinner than the first wall thickness ; positioning the distal end of the inner tubular member in the balloon , with the first segment of the distal leg disposed proximate the distal section of the inner tubular member and the second segment of the distal leg extending distally beyond the distal end of the inner tubular member ; heating the distal leg of the balloon to bond at least a portion of the first segment to the distal section of the inner tubular member and to reduce the second diameter of the second segment of the distal leg .
A photocurable composition comprising: a polymerizable compound; and a photopolymerization initiator, the photocurable composition containing a monofunctional (meth)acryl compound and a compound represented by General Formula shown below as the polymerizable compound wherein, in General Formula , Ar represents a monovalent aromatic group which may have a substituent, R 1 represents an alkyl group which may have a substituent or a hydrogen atom, R 2 represents an alkyl group having (m + n) valences which may have a substituent, m is an integer of 2 or more, and n is an integer of 1 or more. a polymerizable compound; and a photopolymerization initiator, the photocurable composition containing a monofunctional (meth)acryl compound and a compound represented by General Formula shown below as the polymerizable compound wherein, in General Formula , Ar represents a monovalent aromatic group which may have a substituent, R 1 represents an alkyl group which may have a substituent or a hydrogen atom, R 2 represents an alkyl group having (m + n) valences which may have a substituent, m is an integer of 2 or more, and n is an integer of 1 or more.
A method for determining a transmittance of electromagnetic radiation through a contact lens in direct contact with an ocular surface , comprising: measuring a first intensity of radiation reflected by at least a portion of an ocular surface with an intensity measuring device ; positioning a contact lens covering and in direct contact with at least a portion of the ocular surface ; measuring a second intensity of radiation transmitted through the contact lens that is reflected by at least one region of the ocular surface that is covered by the contact lens with the intensity measuring device ; and calculating a transmittance of electromagnetic radiation through the contact lens using the measurements of the first intensity and the second intensity. measuring a first intensity of radiation reflected by at least a portion of an ocular surface with an intensity measuring device ; positioning a contact lens covering and in direct contact with at least a portion of the ocular surface ; measuring a second intensity of radiation transmitted through the contact lens that is reflected by at least one region of the ocular surface that is covered by the contact lens with the intensity measuring device ; and calculating a transmittance of electromagnetic radiation through the contact lens using the measurements of the first intensity and the second intensity.
A permanent magnet synchronous motor comprising: a stator ; and a rotor rotatable relative to the stator, the rotor comprising a magnetic structure with a low coercive force magnet and a high coercive force magnet that are arranged magnetically in series with respect to each other to define a pole of the permanent magnet synchronous motor, a magnetization level of the low coercive force magnet being changeable by a stator current pulse, characterized by a stator magnetomotive force at a rated current being equal to or larger than a product of a magnetic field strength for fully magnetizing the low coercive force magnet and a thickness of the low coercive force magnet, wherein a minimum equivalent magnetization level that is defined by a total magnetomotive force of the low coercive force magnet and the high coercive force magnet is 60 % of a full magnetization level of the low coercive force magnet. a stator ; and a rotor rotatable relative to the stator, the rotor comprising a magnetic structure with a low coercive force magnet and a high coercive force magnet that are arranged magnetically in series with respect to each other to define a pole of the permanent magnet synchronous motor, a magnetization level of the low coercive force magnet being changeable by a stator current pulse, characterized by a stator magnetomotive force at a rated current being equal to or larger than a product of a magnetic field strength for fully magnetizing the low coercive force magnet and a thickness of the low coercive force magnet, wherein a minimum equivalent magnetization level that is defined by a total magnetomotive force of the low coercive force magnet and the high coercive force magnet is 60 % of a full magnetization level of the low coercive force magnet.
A surfactant composition comprising the following components (A), (B), and (C): (A) 45.0% by mass or more and 70.0% by mass or less of an internal olefin sulfonate having 16 or more and 18 or less carbon atoms, (B) 0.5% by mass or more and 25.0% by mass or less of an alpha-olefin sulfonate having 12 or more and 14 or less carbon atoms, and (C) water, wherein the total content of the component (A) and the component (B) is 66.0% by mass or more and 71.0% by mass or less. (A) 45.0% by mass or more and 70.0% by mass or less of an internal olefin sulfonate having 16 or more and 18 or less carbon atoms, (B) 0.5% by mass or more and 25.0% by mass or less of an alpha-olefin sulfonate having 12 or more and 14 or less carbon atoms, and (C) water,
A method for securing an object from forgery, comprising the steps: - supplying (S1) a seal element having an antenna structure ; - supplying (S3) an object to be secured ; - supplying (S2) at least one coupling element arranged at the object or arrangeable at the object , - arranging (S4) the seal element and, where applicable, the at least one coupling element at the object such that a relative arrangement of the antenna structure to the at least one coupling element at the object is fixed, wherein the coupling element is provided and suitable to influence a value of an oscillating circuit parameter of the antenna structure when the antenna structure is arranged relative to the at least one coupling element at the object , and by the arranging, the value of the oscillating circuit parameter of antenna structures arranged at the object is defined in dependence on the fixed relative arrangement, characterized by the further steps of: - measuring (S5) the value of the oscillating circuit parameter of the antenna structure arranged at the object relative to the at least one coupling element by means of a measuring apparatus and - associating (S6, S7) the measured value with the object having the seal element arranged thereto as an authentication feature of the object . - supplying (S1) a seal element having an antenna structure ; - supplying (S3) an object to be secured ; - supplying (S2) at least one coupling element arranged at the object or arrangeable at the object , - arranging (S4) the seal element and, where applicable, the at least one coupling element at the object such that a relative arrangement of the antenna structure to the at least one coupling element at the object is fixed, wherein - measuring (S5) the value of the oscillating circuit parameter of the antenna structure arranged at the object relative to the at least one coupling element by means of a measuring apparatus and - associating (S6, S7) the measured value with the object having the seal element arranged thereto as an authentication feature of the object .
A method of reducing redundant molecular barcodes from a template-dependent primer extension reaction, the method comprising: amplifying a plurality of target nucleic acids using a plurality of pairs of primers that are in a same reaction mixture for three cycles to form a plurality of double-stranded target-specific amplification DNA fragments, wherein each primer pair in said plurality of pairs of primers comprises a forward primer and a reverse primer, wherein the forward primer and reverse primer each includes a 3' end target specific region that is from 8-50 nucleotides, and both the forward primer and the reverse primer include a molecular barcode cassette having a molecular barcode region comprising a 12-40 random nucleotide sequence that is positioned between a 5' end fixed nucleotide sequence region and a 3' end fixed nucleotide sequence region; introducing, following the third cycle, one or a mix of single-stranded DNA specific exonucleases to cleave one or more single-stranded DNA regions on a 5' terminus and a 3' terminus of double-stranded target-specific amplification DNA fragments, wherein the single-stranded DNA regions comprise unmatched base pairs at either terminus of the double-stranded target-specific amplification DNA fragments, leaving a plurality of amplification products with double-stranded DNA termini and intact molecular barcode cassettes on both ends; and amplifying the plurality of amplification products with intact molecular barcode cassettes on both ends with a pair of primers that are complimentary to the 5' end fixed nucleotide sequence region of the molecular barcode cassette. amplifying a plurality of target nucleic acids using a plurality of pairs of primers that are in a same reaction mixture for three cycles to form a plurality of double-stranded target-specific amplification DNA fragments, wherein each primer pair in said plurality of pairs of primers comprises a forward primer and a reverse primer, wherein the forward primer and reverse primer each includes a 3' end target specific region that is from 8-50 nucleotides, and both the forward primer and the reverse primer include a molecular barcode cassette having a molecular barcode region comprising a 12-40 random nucleotide sequence that is positioned between a 5' end fixed nucleotide sequence region and a 3' end fixed nucleotide sequence region; introducing, following the third cycle, one or a mix of single-stranded DNA specific exonucleases to cleave one or more single-stranded DNA regions on a 5' terminus and a 3' terminus of double-stranded target-specific amplification DNA fragments, wherein the single-stranded DNA regions comprise unmatched base pairs at either terminus of the double-stranded target-specific amplification DNA fragments, leaving a plurality of amplification products with double-stranded DNA termini and intact molecular barcode cassettes on both ends; and amplifying the plurality of amplification products with intact molecular barcode cassettes on both ends with a pair of primers that are complimentary to the 5' end fixed nucleotide sequence region of the molecular barcode cassette.
Device for preparing or heating a liquid foodstuff, consisting of two components, specifically a foodstuff preparation container and a base station, characterised in that the drink preparation container can be rotated on the base station and comprises a triple axis digital compass which identifies the angle of rotation and/or the speed of rotation of the foodstuff preparation container and transmits the data to the device electronics unit.