A system for automatically determining a neuromuscular blockade status for a patient to whom a muscle relaxant has been delivered, the system comprising a pressure cuff, wherein a plurality of neuromuscular blockade statuses are predefined in the system, and for each of the neuromuscular blockade statuses are predefined one or more stimulation cycles with a cycle periodicity and one or more criterions for changing from the neuromuscular blockade status to another neuromuscular blockade status, said criterions including a first criterion or first set of criterions for changing the neuromuscular blockade status to a first other neuromuscular blockade status; the system being configured to: automatically perform one or more stimulation cycles predefined for the neuromuscular blockade status; automatically determine, through the pressure cuff applied to a limb of the patient, one or more muscle responses to at least some of the performed stimulation cycles, each of said muscle responses having a form of pressure wave representative of how pressure varies over time in the cuff as a result of limb's muscle reaction to corresponding performed stimulation cycle; automatically compare the muscle responses with the predefined criterions for changing the neuromuscular blockade status; and if the muscle responses fulfil the predefined first criterion or first set of criterions, then automatically perform one or more stimulation cycles predefined for the first other neuromuscular blockade status. a plurality of neuromuscular blockade statuses are predefined in the system, and for each of the neuromuscular blockade statuses are predefined one or more stimulation cycles with a cycle periodicity and one or more criterions for changing from the neuromuscular blockade status to another neuromuscular blockade status, said criterions including a first criterion or first set of criterions for changing the neuromuscular blockade status to a first other neuromuscular blockade status; the system being configured to: automatically perform one or more stimulation cycles predefined for the neuromuscular blockade status; automatically determine, through the pressure cuff applied to a limb of the patient, one or more muscle responses to at least some of the performed stimulation cycles, each of said muscle responses having a form of pressure wave representative of how pressure varies over time in the cuff as a result of limb's muscle reaction to corresponding performed stimulation cycle; automatically compare the muscle responses with the predefined criterions for changing the neuromuscular blockade status; and if the muscle responses fulfil the predefined first criterion or first set of criterions, then automatically perform one or more stimulation cycles predefined for the first other neuromuscular blockade status. automatically perform one or more stimulation cycles predefined for the neuromuscular blockade status; automatically determine, through the pressure cuff applied to a limb of the patient, one or more muscle responses to at least some of the performed stimulation cycles, each of said muscle responses having a form of pressure wave representative of how pressure varies over time in the cuff as a result of limb's muscle reaction to corresponding performed stimulation cycle; automatically compare the muscle responses with the predefined criterions for changing the neuromuscular blockade status; and if the muscle responses fulfil the predefined first criterion or first set of criterions, then automatically perform one or more stimulation cycles predefined for the first other neuromuscular blockade status. <EOS>