mhurhangee/patent-ind-claim-en huggingface dataset:
A cytotoxic protein comprising: a) an immunoglobulin-type binding region comprising one or more polypeptides and capable of specifically binding at least one extracellular target biomolecule, wherein said immunoglobulin-type binding region is derived from an antibody, wherein said extracellular target biomolecule is HER2/neu/ErbB2; and b) a Shiga toxin effector region comprising a polypeptide that is capable of effectuating Shiga toxin A Subunit cytotoxicity, and comprises: an amino acid sequence that is at least 90% identical to the amino acid sequence shown in any of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3; or an amino acid sequence selected from: (i) amino acids 75 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (ii) amino acids 1 to 241 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (iii) amino acids 1 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; and (iv) amino acids 1 to 261 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; wherein the protein is capable of causing death of a cell physically coupled with said HER2/neu/ErbB2; and wherein the binding region and the Shiga toxin effector region are oriented within the protein such that the binding region is located at a position that is more proximal to the carboxyterminus of the Shiga toxin effector region than the amino-terminus of the Shiga toxin effector region. a) an immunoglobulin-type binding region comprising one or more polypeptides and capable of specifically binding at least one extracellular target biomolecule, wherein said immunoglobulin-type binding region is derived from an antibody, wherein said extracellular target biomolecule is HER2/neu/ErbB2; and b) a Shiga toxin effector region comprising a polypeptide that is capable of effectuating Shiga toxin A Subunit cytotoxicity, and comprises: an amino acid sequence that is at least 90% identical to the amino acid sequence shown in any of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3; or an amino acid sequence selected from: (i) amino acids 75 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (ii) amino acids 1 to 241 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (iii) amino acids 1 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; and (iv) amino acids 1 to 261 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; an amino acid sequence that is at least 90% identical to the amino acid sequence shown in any of SEQ ID NO: 1, SEQ ID NO: 2, or SEQ ID NO: 3; or an amino acid sequence selected from: (i) amino acids 75 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (ii) amino acids 1 to 241 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (iii) amino acids 1 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; and (iv) amino acids 1 to 261 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (i) amino acids 75 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (ii) amino acids 1 to 241 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; (iii) amino acids 1 to 251 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3; and (iv) amino acids 1 to 261 of SEQ ID NO:1, SEQ ID NO:2, or SEQ ID NO:3;
Device for selecting and controlling functions of a horological movement, comprising a selector member arranged such that, when it is acted on, it causes a column wheel comprising a plurality of coaxial cams which are integral with one another for rotation as one, to rotate in a single direction of rotation, said device comprising a plurality of transmission yokes , each of which is arranged such that it bears against a cam specific thereto so as to be able to successively occupy, depending on the angular position of said cam , a rest position and an active position, characterised in that each transmission yoke is configured such that when it occupies the active position, it is disposed in the path of a control member which is intended, when it is acted on from a rest position, to drive the transmission yoke located in an active position, towards a position for controlling a function specific thereto.
An injection device adapted for injecting particles into a bone cavity , said injection device comprising: - a reservoir capable of containing at least in part the particles; - an injection needle having a tubular shape around a main axis (AP) and provided with a proximal end fixed to a base of the reservoir and open to the reservoir , and a distal end opposite to the proximal end and open; and characterized in that the device further comprises :- a worm screw movable in rotation around the main axis (AP) inside the injection needle and extending at least from the proximal end up to at least the distal end of the injection needle ; and - an actuator coupled to the worm screw to drive it in rotation. - a reservoir capable of containing at least in part the particles; - an injection needle having a tubular shape around a main axis (AP) and provided with a proximal end fixed to a base of the reservoir and open to the reservoir , and a distal end opposite to the proximal end and open; - an actuator coupled to the worm screw to drive it in rotation.
A powered midwheel drive, MWD, wheelchair (1; 1-1; 1-2; 1-3; 1-4; 1-5; 1-6) comprising: a chassis , a seating system attached to the chassis , the seating system being configured to be manoeuvred between a seated position and a standing position, a pair of drive wheels , a pair of front swing arms (5; 5-6) pivotally connected to the chassis , and front support wheels attached to a respective one of the front swing arms (5; 5-6), wherein each front swing arm (5; 5-6) is configured to pivot in relation to the chassis between a first position, in which the front support wheel is at its uppermost position in relation to the chassis , and a second position, in which the front support wheel is at its lowermost position in relation to the chassis , and wherein the front swing arms (5; 5-6) are configured to pivot to the first position when the seating system is in the standing position, whereby the chassis is tilted forward in relation to the ground or floor surface . a chassis , a seating system attached to the chassis , the seating system being configured to be manoeuvred between a seated position and a standing position, a pair of drive wheels , a pair of front swing arms (5; 5-6) pivotally connected to the chassis , and front support wheels attached to a respective one of the front swing arms (5; 5-6), wherein each front swing arm (5; 5-6) is configured to pivot in relation to the chassis between a first position, in which the front support wheel is at its uppermost position in relation to the chassis , and a second position, in which the front support wheel is at its lowermost position in relation to the chassis , and wherein the front swing arms (5; 5-6) are configured to pivot to the first position when the seating system is in the standing position, whereby the chassis is tilted forward in relation to the ground or floor surface .
An icon management method for a terminal, comprising: displaying a home screen, wherein the home screen comprises a first target icon and a second target icon , the first target icon has at least two non-overlapping function regions, the function regions are corresponding to different functions, and the functions are icon adjustment functions; receiving a first user instruction; determining a first target icon selected by the first user instruction and a target function selected by the first user instruction, wherein the target function is a function corresponding to a function region of the first target icon selected by the first user instruction; and executing the target function on the first target icon selected by the first user instruction, wherein the terminal receives a second user instruction for moving the first target icon on the home screen over the second target icon ; the target function is entering the icon combination mode or entering the icon position adjustment mode; when the target function is entering the icon combination mode, after entering the icon combination mode, the terminal then creates a folder that includes the first target icon and the second target icon ; when the target function is entering the icon position adjustment mode, after entering the icon position adjustment mode, the terminal then adjusts a position of the first target icon and a position of the second target icon . displaying a home screen, wherein the home screen comprises a first target icon and a second target icon , the first target icon has at least two non-overlapping function regions, the function regions are corresponding to different functions, and the functions are icon adjustment functions; receiving a first user instruction; determining a first target icon selected by the first user instruction and a target function selected by the first user instruction, wherein the target function is a function corresponding to a function region of the first target icon selected by the first user instruction; and executing the target function on the first target icon selected by the first user instruction, wherein the terminal receives a second user instruction for moving the first target icon on the home screen over the second target icon ; the target function is entering the icon combination mode or entering the icon position adjustment mode; when the target function is entering the icon combination mode, after entering the icon combination mode, the terminal then creates a folder that includes the first target icon and the second target icon ; when the target function is entering the icon position adjustment mode, after entering the icon position adjustment mode, the terminal then adjusts a position of the first target icon and a position of the second target icon .
Stabilising bar for an orthopaedic aid , the stabilising bar having a first portion and a second portion in the longitudinal direction, the first portion and the second portion being interconnected by a third flexible portion , wherein at least the third flexible portion has a plurality of material recesses , wherein the material recesses are deeper the further away they are from the central region of the third flexible portion , characterised in that the material recesses are formed by tooth-like material protrusions located between the material recesses.
Device for plasma treatment of containers , comprising a process-gas generator for generating a process-gas mixture and at least one plasma station comprising at least one plasma chamber with a treatment space , in which at least one container with a container interior space (5.1) can be used and positioned at the treatment space , wherein the respective plasma chamber is at least partially designed to be evacuable in order to suck a process gas provided by the process-gas generator through the container , which provides its interior space with an internal coating by means of plasma treatment, wherein a plurality of different process gases are present and each process gas is connected to the plasma chamber via its own process-gas line via a process-gas valve (81.1, 82.1, 83.1) located therein, wherein, in at least one process-gas line on the side of the assigned process-gas valve (81.1, 82.1, 83.1) facing away from the plasma chamber at a separately definable buffer distance to the process-gas valve (81.1, 82.1, 83.1), a throttle (81.2, 82.2, 83.2) is arranged, characterized in that the buffer distance is chosen in such a way that the buffer volume of the process gas between the process-gas valve (81.1, 82.1, 83.1) and the throttle (81.2, 82.2, 83.2) is 100 - 500 ml.
An anchor for implantation in a body, comprising: an anchor body adapted to be delivered through a hollow member or delivery device for placement against a tissue surface (F); and a locking mechanism adapted to be delivered through the hollow member or delivery device , wherein the locking mechanism comprises a body having a proximal end and a distal end, and defining a lumen for passage of a flexible member therethrough; wherein the locking mechanism comprises at least two arms , wherein a first arm of the at least two arms is arranged nearer to the proximal end of the body and a second arm of the at least two arms is arranged nearer to the distal end of the body, and wherein the at least two arms are biased to project in opposing directions into the lumen to cinch the flexible member by creating a tortuous path such that the flexible member is uni-directionally advanceable through the lumen relative to the anchor body . an anchor body adapted to be delivered through a hollow member or delivery device for placement against a tissue surface (F); and a locking mechanism adapted to be delivered through the hollow member or delivery device , wherein the locking mechanism comprises a body having a proximal end and a distal end, and defining a lumen for passage of a flexible member therethrough; wherein the locking mechanism comprises at least two arms , wherein a first arm of the at least two arms is arranged nearer to the proximal end of the body and a second arm of the at least two arms is arranged nearer to the distal end of the body, and wherein the at least two arms are biased to project in opposing directions into the lumen to cinch the flexible member by creating a tortuous path such that the flexible member is uni-directionally advanceable through the lumen relative to the anchor body .
Vessel selected from crucibles, pans, open cups and saggars comprising of two components, from which (A) one component being a monolithic ceramic material, (B) the second component being a ceramic matrix composite comprising fibers embedded in ceramic oxide or non-oxide matrices wherein non-oxide ceramics are selected from carbides and borides and nitrides, wherein at least 90% by weight of such vessels are either component (A) or component (B) and wherein component (A) is the inner part. (A) one component being a monolithic ceramic material, (B) the second component being a ceramic matrix composite comprising fibers embedded in ceramic oxide or non-oxide matrices wherein non-oxide ceramics are selected from carbides and borides and nitrides,
A non-transitory machine readable medium having stored thereon instructions for performing a method of migrating operations between CPU cores, comprising machine executable code that when executed by at least one machine (108.a), causes the machine to: during an initialization, execute a plurality of tasks and a plurality of interrupt service routines, ISRs, on a first core; after completing the initialization, migrate the plurality of tasks and the plurality of ISRs across a plurality of cores (204.a-204.d), including: accessing a mapping that associates the plurality of tasks and the plurality of ISRs with the plurality of cores; based on the mapping, assigning the plurality of tasks to the plurality of cores as assigned tasks; based on the mapping, assigning one or more interrupts to the plurality of cores as assigned interrupts, the one or more interrupts corresponding to the plurality of ISRs; handling the assigned interrupts on the plurality of cores; executing the assigned tasks on the plurality of cores; characterised in that : responsive to detecting that an operation request rate has decreased below a pre-configured or user-specified threshold, reducing a per operation latency by migrating the plurality of tasks and the plurality of ISRs to a single core of the plurality of cores. during an initialization, execute a plurality of tasks and a plurality of interrupt service routines, ISRs, on a first core; after completing the initialization, migrate the plurality of tasks and the plurality of ISRs across a plurality of cores (204.a-204.d), including: accessing a mapping that associates the plurality of tasks and the plurality of ISRs with the plurality of cores; based on the mapping, assigning the plurality of tasks to the plurality of cores as assigned tasks; based on the mapping, assigning one or more interrupts to the plurality of cores as assigned interrupts, the one or more interrupts corresponding to the plurality of ISRs; handling the assigned interrupts on the plurality of cores; executing the assigned tasks on the plurality of cores; characterised in that : responsive to detecting that an operation request rate has decreased below a pre-configured or user-specified threshold, reducing a per operation latency by migrating the plurality of tasks and the plurality of ISRs to a single core of the plurality of cores. accessing a mapping that associates the plurality of tasks and the plurality of ISRs with the plurality of cores; based on the mapping, assigning the plurality of tasks to the plurality of cores as assigned tasks; based on the mapping, assigning one or more interrupts to the plurality of cores as assigned interrupts, the one or more interrupts corresponding to the plurality of ISRs; handling the assigned interrupts on the plurality of cores; executing the assigned tasks on the plurality of cores; characterised in that : responsive to detecting that an operation request rate has decreased below a pre-configured or user-specified threshold, reducing a per operation latency by migrating the plurality of tasks and the plurality of ISRs to a single core of the plurality of cores.
Cable support for distribution boxes , in particular for FTTH environments, the cable support comprising at least one cable passage , the at least one cable passage adapted to receive at least one cable , wherein the cable support is a stackable modular assembly of at least two segment blocks , each of which form, at a respective end thereof pointing in or against a stacking direction (S), a part of the at least one cable passage , wherein at least one end of a segment block comprises at least one positive locking member , the positive locking member being formed complementary to a positive locking member at an end of another segment block ; characterized in that the cable support and each segment block is provided with access openings for inserting a rod-like dismounting tool , the access openings of adjacent segments blocks of the cable support are aligned with each other such that the dismounting tool may be inserted along an access axis (A) extending parallel to the stacking direction, the positive locking member including at least one resiliently deflectable latch member is located on the access axis (A), so that by inserting a dismounting tool into the cable support , the positive lock between the positive locking member and the complementary at least one resiliently deflectable latch member is released.
A blade outer air seal for a gas turbine engine , comprising: a body including lateral edges , , radial edges , , and an outer surface , wherein the lateral edges , and the radial edges , provide sealing and containment for a rotating turbomachine blade, the outer surface of the body including a plurality of raised material surfaces that are spaced about the outer surface , the plurality of raised material surfaces extending beyond the outer surface of the body , the plurality of raised material surfaces comprising chamfered edges and being substantially smaller than the outer surface , a plurality of holes distributed among the plurality of raised material surfaces , wherein the plurality of holes are a plurality of raised inlet holes formed through the plurality of raised material surfaces and formed perpendicular to the body so that each of the plurality of holes is raised above the body , and wherein the plurality of raised surfaces create convoluted air flow paths to be received by the plurality of holes , and wherein the radial edges include exit holes in fluid communication with the plurality of raised inlet holes . a body including lateral edges , , radial edges , , and an outer surface , wherein the lateral edges , and the radial edges , provide sealing and containment for a rotating turbomachine blade, the outer surface of the body including a plurality of raised material surfaces that are spaced about the outer surface , the plurality of raised material surfaces extending beyond the outer surface of the body , the plurality of raised material surfaces comprising chamfered edges and being substantially smaller than the outer surface , a plurality of holes distributed among the plurality of raised material surfaces , wherein the plurality of holes are a plurality of raised inlet holes formed through the plurality of raised material surfaces and formed perpendicular to the body so that each of the plurality of holes is raised above the body , and wherein the plurality of raised surfaces create convoluted air flow paths to be received by the plurality of holes , and wherein the radial edges include exit holes in fluid communication with the plurality of raised inlet holes .
A method by a mobile node in a wireless network, comprising: receiving an indicator related to mobility of the mobile node; determining , from the received indicator, that the mobile node has a no-mobility status wherein the mobile node is determined to have the no-mobility status when an indicator of a connection to a stationary external power source is received; determining , in accordance with the indicator of the connection to the external power source, a charging status of the mobile node transmitting an indication of the determined no-mobility status to the wireless network; transmitting an indication of the mobile node's charging status to a node in the wireless network, wherein the indication of the mobile node's charging status comprises an identification of the power source type; and receiving , after transmitting the indication of the mobile node's no-mobility status to the wireless network, instructions from the wireless network that the mobile node is to function as a node for relaying signals between the wireless network and one or more other wireless nodes. receiving an indicator related to mobility of the mobile node; determining , from the received indicator, that the mobile node has a no-mobility status wherein the mobile node is determined to have the no-mobility status when an indicator of a connection to a stationary external power source is received; determining , in accordance with the indicator of the connection to the external power source, a charging status of the mobile node transmitting an indication of the determined no-mobility status to the wireless network; transmitting an indication of the mobile node's charging status to a node in the wireless network, wherein the indication of the mobile node's charging status comprises an identification of the power source type; and receiving , after transmitting the indication of the mobile node's no-mobility status to the wireless network, instructions from the wireless network that the mobile node is to function as a node for relaying signals between the wireless network and one or more other wireless nodes.
A method for preparing a glycan from a glycoprotein, comprising: (I) a step of obtaining a glycan-containing sample by bringing a glycan releasing solution that contains a hydroxylamine compound and a basic reagent into contact with the glycoprotein and releasing the glycan from the glycoprotein; (II) a step of adsorbing a glycan having a length of a monosaccharide or more on a purifying agent for purifying the glycan by bringing the glycan-containing sample into contact with the purifying agent, which is composed of a compound having a betaine structure; and (III) a step of eluting the glycan from the purifying agent. (I) a step of obtaining a glycan-containing sample by bringing a glycan releasing solution that contains a hydroxylamine compound and a basic reagent into contact with the glycoprotein and releasing the glycan from the glycoprotein; (II) a step of adsorbing a glycan having a length of a monosaccharide or more on a purifying agent for purifying the glycan by bringing the glycan-containing sample into contact with the purifying agent, which is composed of a compound having a betaine structure; and (III) a step of eluting the glycan from the purifying agent.