mhurhangee/patent-ind-claim-en huggingface dataset:
Anlotinib or a pharmaceutically acceptable salt thereof, for use in inhibiting osteosarcoma and/or chondrosarcoma in a patient in need of treatment.
A method for producing sausage-shaped products (S), like sausages, containing a flowable filling material in a tubular or bag-shaped packaging casing (M), on a clipping machine , the method comprises the steps of: - feeding the filling material in a feeding direction (F) into the tubular or bag-shaped packaging casing (M) stored on a filling tube having a front end , and being closed at the front end by closure means, like a closing clip (C); - limiting the movement of the tubular or bag-shaped packaging casing (M) while being pulled-off from the filling tube by a casing brake assembly arranged on the filling tube ; - gathering the filled tubular or bag-shaped packaging casing (M) by gathering means arranged downstream the filling tube , for forming a plait-like portion (P) thereto; and - placing and closing at least one closure means (C) on the plait-like portion (P) for closing the filled tubular or bag-shaped packaging casing (M); wherein the casing brake assembly can reversibly be moved between a second position (II) in which the casing brake assembly is positioned close to the front end of the filling tube , and a first position (I) in which the casing brake assembly is positioned a predefined distance upstream the second position (II), wherein the casing brake assembly is moved from the first position (I) into the second position (II) during the feeding of the filling material into the tubular or bag-shaped packaging casing (M), and is moved back into the first position (I) after the feeding of filling material has been stopped. - feeding the filling material in a feeding direction (F) into the tubular or bag-shaped packaging casing (M) stored on a filling tube having a front end , and being closed at the front end by closure means, like a closing clip (C); - limiting the movement of the tubular or bag-shaped packaging casing (M) while being pulled-off from the filling tube by a casing brake assembly arranged on the filling tube ; - gathering the filled tubular or bag-shaped packaging casing (M) by gathering means arranged downstream the filling tube , for forming a plait-like portion (P) thereto; and - placing and closing at least one closure means (C) on the plait-like portion (P) for closing the filled tubular or bag-shaped packaging casing (M); wherein the casing brake assembly can reversibly be moved between a second position (II) in which the casing brake assembly is positioned close to the front end of the filling tube , and a first position (I) in which the casing brake assembly is positioned a predefined distance upstream the second position (II), wherein the casing brake assembly is moved from the first position (I) into the second position (II) during the feeding of the filling material into the tubular or bag-shaped packaging casing (M), and is moved back into the first position (I) after the feeding of filling material has been stopped.
Follicle-stimulating hormone (FSH) ligand which potentiates the bioactivity of FSH, of luteinizing hormone (LH), and of chorionic gonadotropin (CG), characterized in that said ligand is an antibody or a fragment thereof and in that : the heavy chain variable domain contains the following CDRs: - VH-CDR1, defined by the sequence GFTFSSSY (SEQ ID NO: 5); - VH-CDR2, defined by the sequence IYAGTGGT (SEQ ID NO: 6); - VH-CDR3, defined by the sequence ARHGSYFDY (SEQ ID NO: 7); and the light chain variable domain contains the following CDRs: - VL-CDR1, defined by the sequence QSVDYDGDSY (SEQ ID NO: 8); - VL-CDR2, defined by the sequence AAS; - VL-CDR3, defined by the sequence QQSNEDPYT (SEQ ID NO: 9). the heavy chain variable domain contains the following CDRs: - VH-CDR1, defined by the sequence GFTFSSSY (SEQ ID NO: 5); - VH-CDR2, defined by the sequence IYAGTGGT (SEQ ID NO: 6); - VH-CDR3, defined by the sequence ARHGSYFDY (SEQ ID NO: 7); and - VH-CDR1, defined by the sequence GFTFSSSY (SEQ ID NO: 5); - VH-CDR2, defined by the sequence IYAGTGGT (SEQ ID NO: 6); - VH-CDR3, defined by the sequence ARHGSYFDY (SEQ ID NO: 7); and the light chain variable domain contains the following CDRs: - VL-CDR1, defined by the sequence QSVDYDGDSY (SEQ ID NO: 8); - VL-CDR2, defined by the sequence AAS; - VL-CDR3, defined by the sequence QQSNEDPYT (SEQ ID NO: 9). - VL-CDR1, defined by the sequence QSVDYDGDSY (SEQ ID NO: 8); - VL-CDR2, defined by the sequence AAS; - VL-CDR3, defined by the sequence QQSNEDPYT (SEQ ID NO: 9).
Vehicle door with a handle arrangement , wherein the vehicle door comprises at least: - a door support structure , - a channel strip which is arranged on the upper side of the door support structure , wherein the handle arrangement is arranged movably, in particular pivotably, on the channel strip , and comprises a handle element which is grippable on an outer side of the vehicle door , and wherein the handle element is configured as a device which is actuable in at least one direction (R1, R2) for active actuation of at least two switching functions. - a door support structure , - a channel strip which is arranged on the upper side of the door support structure , wherein the handle arrangement is arranged movably, in particular pivotably, on the channel strip , and comprises a handle element which is grippable on an outer side of the vehicle door , and wherein the handle element is configured as a device which is actuable in at least one direction (R1, R2) for active actuation of at least two switching functions.
Unlocking mechanism for locking and unlocking a plug-in connection of a vacuum cleaner between a housing of the vacuum cleaner and a suction tube and/or between the housing and a suction nozzle and/or between the suction tube and the suction nozzle , the unlocking mechanism comprising an unlocking element for unlocking the plug-in connection , the unlocking element being movable between an unlocking position, in which it unlocks the unlocking mechanism , and a locking position, in which it locks the unlocking mechanism , the unlocking mechanism comprising at least one clamping wedge which, in the unlocking position, enters a recess of the unlocking element , in the locking position, the clamping wedge being supported against the unlocking element and locking the plug-in connection , characterised in that the unlocking element is displaceable between an unlocking position and a locking position.
Moulding machine comprising a workstation including a device for holding a sheet-shaped element during the introduction phase thereof in the workstation , said holding device comprising a suctioning member able to partially retain each sheet by the rear portion thereof during the phase of introducing said sheet in said workstation , characterised in that the holding device further includes blowing means capable of flattening the rear portion of each sheet against the suctioning member during the introduction phase.
A depalletizing system for picking up a plurality of objects to move the picked up objects to a predetermined position, comprising: a camera unit for acquiring image data of tops of the plurality of objects; a controller for performing vision recognition for the acquired image data of tops of the plurality of objects to determine whether two neighboring objects among the plurality of objects are simultaneously pickable; and a picking robot for simultaneously picking up the two objects determined as simultaneously pickable objects to move the picked up objects to the predetermined position, wherein the controller produces a depth map from the image data of tops of the plurality of objects and selects any object that has the highest top level among the plurality of objects as a reference object according to the produced depth map, characterized in that the controller determines whether the neighboring object of the reference object has the same size and surface image as the reference object to determine whether the reference object and the neighboring object are simultaneously pickable according to the determined result. a camera unit for acquiring image data of tops of the plurality of objects; a controller for performing vision recognition for the acquired image data of tops of the plurality of objects to determine whether two neighboring objects among the plurality of objects are simultaneously pickable; and a picking robot for simultaneously picking up the two objects determined as simultaneously pickable objects to move the picked up objects to the predetermined position, wherein the controller produces a depth map from the image data of tops of the plurality of objects and selects any object that has the highest top level among the plurality of objects as a reference object according to the produced depth map, characterized in that the controller determines whether the neighboring object of the reference object has the same size and surface image as the reference object to determine whether the reference object and the neighboring object are simultaneously pickable according to the determined result.
An adjustable friction slider assembly comprising: a rail member ; and a carriage assembly moveably coupled to the rail member , the carriage assembly comprising: a bracket member ; and a plurality of roller elements moveably coupled to the rail member and coupled to the bracket member using a plurality of attachment members , characterized in that the plurality of roller elements comprises at least one adjustable roller element coupled to the bracket member using a moveable attachment member , wherein moving the moveable attachment member adjusts a friction between the plurality of roller elements and the rail member . a rail member ; and a carriage assembly moveably coupled to the rail member , the carriage assembly comprising: a bracket member ; and a plurality of roller elements moveably coupled to the rail member and coupled to the bracket member using a plurality of attachment members , characterized in that the plurality of roller elements comprises at least one adjustable roller element coupled to the bracket member using a moveable attachment member , wherein moving the moveable attachment member adjusts a friction between the plurality of roller elements and the rail member . a bracket member ; and a plurality of roller elements moveably coupled to the rail member and coupled to the bracket member using a plurality of attachment members , characterized in that the plurality of roller elements comprises at least one adjustable roller element coupled to the bracket member using a moveable attachment member , wherein moving the moveable attachment member adjusts a friction between the plurality of roller elements and the rail member .
A needleless connector , comprising: a housing having a proximal end defining an inlet port of the housing, a distal end including a base defining an outlet port of the housing, and an inner surface defining an internal cavity extending between the inlet and outlet ports; and a compressible valve reciprocally disposed within the internal cavity and configured to contact at least a portion of the inner surface , the compressible valve comprising a head portion and a compressible body portion extending distally from the head portion, wherein: in a closed state of the compressible valve, a top section of the head portion of the compressible valve has a planar shape configured to contact and seal against the inner surface of the housing; and in an open state, where the compressible valve is subject to an axial force: the top section of the head portion is lodged between two pinch points (P) thereof between opposing walls of an inwardly angled portion of the internal surface ; and the top section of the head portion has a non-planar shape defining a fluid path extending at least partially between opposing walls on an outwardly angled portion of the internal surface . a housing having a proximal end defining an inlet port of the housing, a distal end including a base defining an outlet port of the housing, and an inner surface defining an internal cavity extending between the inlet and outlet ports; and a compressible valve reciprocally disposed within the internal cavity and configured to contact at least a portion of the inner surface , the compressible valve comprising a head portion and a compressible body portion extending distally from the head portion, in a closed state of the compressible valve, a top section of the head portion of the compressible valve has a planar shape configured to contact and seal against the inner surface of the housing; and in an open state, where the compressible valve is subject to an axial force: the top section of the head portion is lodged between two pinch points (P) thereof between opposing walls of an inwardly angled portion of the internal surface ; and the top section of the head portion has a non-planar shape defining a fluid path extending at least partially between opposing walls on an outwardly angled portion of the internal surface . the top section of the head portion is lodged between two pinch points (P) thereof between opposing walls of an inwardly angled portion of the internal surface ; and the top section of the head portion has a non-planar shape defining a fluid path extending at least partially between opposing walls on an outwardly angled portion of the internal surface .
A plug element for a connection system of a welding torch , which is connected to the connection system via at least one hose package , wherein a welding wire conveyed by a feed unit arranged on a motor plate and gas are guided to the welding torch via the hose package , wherein the plug-in element is provided at least with a bolt , at the free end of which an inlet nozzle for a welding wire is arranged, wherein at least the bolt is designed for fastening to a connecting device formed by an end region of the motor plate , characterized in that - the plug element has a connection arranged on a circle around the bolt in a first plane and formed for transmission of the gas as an obligatorily required medium, and thirteen additional connections are arranged on this circle for transmission of additional media in addition to the gas, namely eleven control signals , an air and a data bus , - the bolt has an area for transmitting a welding current as an obligatorily required medium in a second plane , - the inlet nozzle for the welding wire as an obligatorily required medium is arranged in a third plane , and - the bolt has a groove for a locking system of a current coupling between the first plane and the third plane . - the plug element has a connection arranged on a circle around the bolt in a first plane and formed for transmission of the gas as an obligatorily required medium, and thirteen additional connections are arranged on this circle for transmission of additional media in addition to the gas, namely eleven control signals , an air and a data bus , - the bolt has an area for transmitting a welding current as an obligatorily required medium in a second plane , - the inlet nozzle for the welding wire as an obligatorily required medium is arranged in a third plane , and - the bolt has a groove for a locking system of a current coupling between the first plane and the third plane .
A solid carbon dioxide sorbent for adsorbing carbon dioxide from a gas mixture, comprising a modified polyamine which is supported upon and within or bound to a solid support, wherein the modified polyamine is the reaction product of an amine and an epoxide; and wherein the amine being selected from the group consisting of tetraethylenepentaamine, pentaethylenehexamine, triethylenetetramine, diethylenetriamine, ethylenediamine, hexaethyleneheptamine, and mixtures thereof, and wherein the solid support is fumed silica or precipitated silica.
Motor-adjustable steering column for a motor vehicle, comprising a support unit which can be connected to a vehicle body and by which an actuating unit is held, which comprises a steering spindle which is mounted rotatably about a longitudinal axis (L) in a casing unit , the casing unit having at least two casing tubes which can be adjusted relative to one another and are connected to an adjustment drive , which has a coupling rod extending along its coupling axis (S), which engages on casing tubes which are adjustable relative to one another, and which is operatively connected to a motorized drive unit and can be adjusted by the drive unit relative to at least one of the casing tubes , a deflection limiting device being arranged between the casing unit and the coupling rod , characterized in in that the deflection-limiting device limits a deflection of the coupling rod transversely to the coupling axis (S), the deflection-limiting device having a guide opening which at least partially embraces the coupling rod , the coupling rod having a defined play in the guide opening , so that a loose form fit is realized in the transverse direction.
An intraluminal ultrasound imaging device , comprising: a cable comprising a proximal portion and a distal portion; an electrical connector coupled to the proximal portion of the cable; a flexible elongate member comprising a proximal portion and a distal portion, wherein the distal portion of the flexible elongate member is configured to be positioned within a body lumen of a patient, wherein the proximal portion of the flexible elongate member is coupled to the cable; an ultrasound transducer array coupled to the distal portion of the flexible elongate member; a first plurality of conductors extending within the cable; characterized in that a second plurality of conductors is extending within the flexible elongate member, wherein each conductor of the first plurality of conductors is electrically coupled to a respective conductor of the second plurality of conductors, wherein a conductor of the first plurality of conductors with a first cross section is electrically coupled to a conductor of the second plurality of conductors with a second cross section that is smaller than the first cross section, and wherein the first plurality of conductors and the second plurality of conductors are configured to transmit electrical signals between the ultrasound transducer array and the electrical connector. a cable comprising a proximal portion and a distal portion; an electrical connector coupled to the proximal portion of the cable; a flexible elongate member comprising a proximal portion and a distal portion, wherein the distal portion of the flexible elongate member is configured to be positioned within a body lumen of a patient, wherein the proximal portion of the flexible elongate member is coupled to the cable; an ultrasound transducer array coupled to the distal portion of the flexible elongate member; a first plurality of conductors extending within the cable; characterized in that a second plurality of conductors is extending within the flexible elongate member, wherein each conductor of the first plurality of conductors is electrically coupled to a respective conductor of the second plurality of conductors, wherein a conductor of the first plurality of conductors with a first cross section is electrically coupled to a conductor of the second plurality of conductors with a second cross section that is smaller than the first cross section, and wherein the first plurality of conductors and the second plurality of conductors are configured to transmit electrical signals between the ultrasound transducer array and the electrical connector.
A preform for making a carbon-carbon composite comprising: a plurality of layers comprising carbon fibers or carbon-precursor fibers, wherein the plurality of layers are stacked along a central axis to form a stack, wherein the plurality of layers comprise a first exterior layer defining a first major surface of the preform, a second exterior layer defining a second major surface of the preform opposite the first major surface, and at least one interior layer disposed between the first exterior layer and the second exterior layer, the at least one interior layer having a peripheral region that forms a portion of an outer surface of the preform; and a plurality of needled fibers, wherein at least some needled fibers of the plurality of needled fibers extend through two or more layers of the plurality of layers; wherein the preform has an exterior region and a core region, wherein the exterior region fully surrounds the core region, and wherein the exterior region includes at least the peripheral region of the at least one interior layer; wherein the plurality of needled fibers define a first needled fiber number density, NFND, in the exterior region and a second NFND in at least a portion of the core region, wherein the second NFND is greater than the first NFND. a plurality of layers comprising carbon fibers or carbon-precursor fibers, wherein the plurality of layers are stacked along a central axis to form a stack, wherein the plurality of layers comprise a first exterior layer defining a first major surface of the preform, a second exterior layer defining a second major surface of the preform opposite the first major surface, and at least one interior layer disposed between the first exterior layer and the second exterior layer, the at least one interior layer having a peripheral region that forms a portion of an outer surface of the preform; and a plurality of needled fibers, wherein at least some needled fibers of the plurality of needled fibers extend through two or more layers of the plurality of layers; wherein the preform has an exterior region and a core region, wherein the exterior region fully surrounds the core region, and wherein the exterior region includes at least the peripheral region of the at least one interior layer; wherein the plurality of needled fibers define a first needled fiber number density, NFND, in the exterior region and a second NFND in at least a portion of the core region, wherein the second NFND is greater than the first NFND.
A holding device , comprising: a supporter supporting a weight of a workpiece (W) in a first direction, the first direction being along a vertical direction; a limiter suppressing movement in a horizontal direction of the workpiece (W) supported by the supporter ; and a first driver moving the supporter with respect to the limiter in a second direction, the second direction being perpendicular to the first direction, a tilt of the supporter being changeable with respect to the limiter along a plane including the first and second directions, characterized in that , the holding device further comprises a second driver moving the limiter in the second direction. a supporter supporting a weight of a workpiece (W) in a first direction, the first direction being along a vertical direction; a limiter suppressing movement in a horizontal direction of the workpiece (W) supported by the supporter ; and a first driver moving the supporter with respect to the limiter in a second direction, the second direction being perpendicular to the first direction, a tilt of the supporter being changeable with respect to the limiter along a plane including the first and second directions, characterized in that , the holding device further comprises a second driver moving the limiter in the second direction.