mhurhangee/patent-ind-claim-en huggingface dataset:
A non-glucocorticoidal compound which (a) is capable of binding to a T-cell adhesion molecule, and/or (b) is capable of blocking the binding site of a T-cell adhesion molecule, and which decreases or inhibits the binding of mammalian T-cells to mammalian endothelial cells, for use in a method of prophylaxis and/or treatment of neurological adverse events caused by the administration of a medicament which comprises re-directing of T-cells against target cells in a patient, wherein said medicament is a CD19 x CD3 bispecific single chain antibody, wherein the non-glucocorticoidal compound is to be administered prior to and concomitantly with (i) an initial dosing, (ii) a re-exposure; and/or (iii) an increase of said administration of a CD19 x CD3 bispecific single chain antibody, wherein said neurological adverse events are one or more of disorientation/confusion, word finding problems/aphasia, seizure, kinetic tremor, ataxia, dysarthria and handwriting problems, wherein said patient is a mammal. (a) is capable of binding to a T-cell adhesion molecule, and/or (b) is capable of blocking the binding site of a T-cell adhesion molecule,
Use of a material comprising at least one compound related to a ferrous-ferric lamellar double hydroxide (LDH), said compound having at least one divalent cation D II , and at least one trivalent cation T III , of the following general formula: [D II 3n(1-x) T III 3nx O 6n H n(7-3x) ] n+ [A n- , m H 2 O] n- (I) in which A n- is an anion of charge n, n having the values 1, 2 or 3, in particular 2, m is an integer in the range from 1 to 10, in particular from 1 to 4, advantageously 3, and x is comprised from 0 to 1, said compound comprising a minimum proportion of Fe II of 1% permitting the transformation of an Fe II ion into Fe III , for implementing an electrode in energy storage devices such as electric cells, batteries, accumulators or supercapacitors, the theoretical electrical energy capacity of said electrode is greater than or equal to 160 Ah/kg, in particular 245 Ah/kg. in which A n- is an anion of charge n, n having the values 1, 2 or 3, in particular 2, m is an integer in the range from 1 to 10, in particular from 1 to 4, advantageously 3, and x is comprised from 0 to 1, said compound comprising a minimum proportion of Fe II of 1% permitting the transformation of an Fe II ion into Fe III , for implementing an electrode in energy storage devices such as electric cells, batteries, accumulators or supercapacitors, the theoretical electrical energy capacity of said electrode is greater than or equal to 160 Ah/kg, in particular 245 Ah/kg.
A method of cooling at least a portion of a turbine bucket comprising a platform , the method comprising: during operation of a turbine, altering a swirl velocity of purge air beneath a platform lip extending axially from the platform of the turbine bucket , wherein altering the swirl velocity of the purge air includes interrupting a flow of the purge air with a plurality of voids disposed along a length of an angel wing extending axially from a face , of a shank portion of the turbine bucket , characterized in that said plurality of voids are disposed along an angel wing rim at a distal end of the angel wing or at a distal end of the platform lip such that the remaining portions of the angel wing rim or the platform lip form a plurality of column members . during operation of a turbine, altering a swirl velocity of purge air beneath a platform lip extending axially from the platform of the turbine bucket , wherein altering the swirl velocity of the purge air includes interrupting a flow of the purge air with a plurality of voids disposed along a length of an angel wing extending axially from a face , of a shank portion of the turbine bucket , characterized in that said plurality of voids are disposed along an angel wing rim at a distal end of the angel wing or at a distal end of the platform lip such that the remaining portions of the angel wing rim or the platform lip form a plurality of column members .
An oral care composition, comprising: zinc phosphate, wherein the zinc phosphate is added to the oral care composition as a preformed salt, and the amount of zinc phosphate is 0.8 to 2% by weight, relative to the weight of the oral care composition; and at least one anti-microbial agent chosen from eugenol, isoeugenol, eugenol acetate and isoeugenol acetate and the amount of the anti-microbial agent is from 0.3 to 0.7 % by weight, relative to the weight of the oral care composition; and an effective amount of a fluoride ion source; and an effective amount of one or more alkali phosphate salts, wherein the oral care composition is essentially free of thymol and terpineol. zinc phosphate, wherein the zinc phosphate is added to the oral care composition as a preformed salt, and the amount of zinc phosphate is 0.8 to 2% by weight, relative to the weight of the oral care composition; and at least one anti-microbial agent chosen from eugenol, isoeugenol, eugenol acetate and isoeugenol acetate and the amount of the anti-microbial agent is from 0.3 to 0.7 % by weight, relative to the weight of the oral care composition; and an effective amount of a fluoride ion source; and an effective amount of one or more alkali phosphate salts, wherein the oral care composition is essentially free of thymol and terpineol.
Set made of a hollow body which comprises an inlet opening for the entry of an air stream to be purified and an outlet opening for the outlet of the purified air stream, and multiple purifying substructures for purifying the air stream by a deposition of particles and/or for a filtration of the airstream, which purifying substructures include deposition structures for purifying an airstream, wherein the deposition structures encompass at least two impact walls which are successive in the direction of the airstream, which are provided with openings , wherein the purifying substructures are successively arrangeable in the hollow body in the direction of the airstream, characterized in that at least two different combinations of purifying substructures are arrangeable in the hollow body , that the deposition structures , by the size of the openings , are matched to the deposition of particles of a different size, and that the deposition structures are provided in different thicknesses .
A zipped tarpaulin with at least one of its walls comprising a zipper with a slider wherein the zipper is arranged horizontally along the lower edge of the wall , between said wall and a longitudinal element in the lower part of the wall , characterised in that it has at least one additional row of teeth enabling the zipper to be fastened at various levels and the height of the tarpaulin to be adapted for semi-trailers with a raised roof.
Arrangement consisting of a glass syringe (303; 403) and an assembly auxiliary element (304; 404) for providing an interface element between the glass syringe (303; 403), which comprises, on the front end, a syringe cone part having a syringe needle (309; 409) and, on the rear end, a flange part, and a glass syringe operating means , the assembly auxiliary element (304; 404) being secured to the glass syringe (303; 403) in front of the flange part relative to the syringe needle (309; 409) such that a reference point of the assembly auxiliary element (304; 404) is always at a defined distance (318; 418) from the syringe needle tip (319; 419) and in the same axial and radial position relative to said syringe needle tip, the assembly auxiliary element (304; 404) being arranged on an outer contour (314; 414) of the glass syringe (303; 403), characterised in that the assembly auxiliary element (304; 404) is injection-moulded, adhered or welded onto the glass syringe (303; 403), the assembly element (304; 404) comprising a securing means by means of which the assembly auxiliary element (304; 404), arranged on the outer contour (314; 414) of the glass syringe (303; 403), is secured to the glass syringe (303; 403) in front of the flange part relative to the syringe needle (309; 409) such that a defined distance (318; 418) is always formed between a reference point of the assembly auxiliary element (304; 404) and the needle tip (319; 419) of the syringe needle (309; 409), the securing means having a receiving area for receiving the syringe cone part , by means of which the assembly auxiliary element is secured to the syringe cone part and thus to the glass syringe , or the securing means having a receiving area for receiving a shoulder region of the glass syringe , the assembly auxiliary element being secured to the shoulder region and thus to the glass syringe , the assembly auxiliary element (304; 404) comprising a holding device (321; 421) arranged on the outer peripheral side of the assembly auxiliary element (304; 404), by means of which the assembly auxiliary element (304; 404) is held on the glass syringe operating means , the holding device (321; 421) having a specific outer structure in the form of a tongue- and-groove configuration, respective grooves and tongues being arranged such that they extend in the peripheral direction and/or in the longitudinal direction of the assembly auxiliary element (304; 404), and a counter structure which interacts with the holding device (321; 421) being formed on the glass syringe operating means .
A composition, comprising: at least one polyester matrix resin which is a polyethylene terephthalate resin (PET) that has an amount of isophthalic acid (IPA) monomer units of up to 6% by mole based upon the total number of moles dicarboxylic acid monomer units, at least one filler selected from the group consisting of an organo-clay exfoliated in a polyamide comprising polymerized units of m-xylene diamine (MXDA) and an organo-clay in the form of nano-platelets, and a co-polyamide co-barrier resin in a amount of from 2 to 6 wt% based on the total weight of the composition, wherein the co-polyamide co-barrier resin further comprises reacted units of meta-xylene diamine, adipic acid, and isophthalic acid and is dispersed in the polyester matrix resin. wherein the polyester matrix resin is obtained by polymerizing a mixture comprising at least one dicarboxylic acid and at least one diol, and wherein the polyester matrix resin has an intrinsic viscosity determined in accordance with ASTM D4603 of from 0.7 to 0.9 at 30 °C in a mixed solvent of 60% phenol and 40% 1,1,2,2-tetrachloroethane, wherein % is wt % based on the total weight of phenol and 1,1,2,2-tetrachloroethane. at least one polyester matrix resin which is a polyethylene terephthalate resin (PET) that has an amount of isophthalic acid (IPA) monomer units of up to 6% by mole based upon the total number of moles dicarboxylic acid monomer units, at least one filler selected from the group consisting of an organo-clay exfoliated in a polyamide comprising polymerized units of m-xylene diamine (MXDA) and an organo-clay in the form of nano-platelets, and a co-polyamide co-barrier resin in a amount of from 2 to 6 wt% based on the total weight of the composition, wherein the co-polyamide co-barrier resin further comprises reacted units of meta-xylene diamine, adipic acid, and isophthalic acid and is dispersed in the polyester matrix resin. wherein the polyester matrix resin is obtained by polymerizing a mixture comprising at least one dicarboxylic acid and at least one diol, and wherein the polyester matrix resin has an intrinsic viscosity determined in accordance with ASTM D4603 of from 0.7 to 0.9 at 30 °C in a mixed solvent of 60% phenol and 40% 1,1,2,2-tetrachloroethane, wherein % is wt % based on the total weight of phenol and 1,1,2,2-tetrachloroethane.
A printed circuit board, PCB, configured with radio-frequency functionality, the PCB comprising: a PCB structure comprising a plurality of layers, wherein at least one internal layer arranged within the PCB structure comprises one or more printed radio-frequency, RF, structures comprising an antenna and a transmission line; and at least one embedded element comprising an absorbing material provided within the PCB structure, further comprising a conductive structure configured to substantially surround the absorbing material , wherein the conductive structure is configured to generate a reflection coefficient and/or loss to improve a match of the antenna to the transmission line via holes placed around the circumference of the absorbing material. a PCB structure comprising a plurality of layers, wherein at least one internal layer arranged within the PCB structure comprises one or more printed radio-frequency, RF, structures comprising an antenna and a transmission line; and at least one embedded element comprising an absorbing material provided within the PCB structure, further comprising a conductive structure configured to substantially surround the absorbing material , wherein the conductive structure is configured to generate a reflection coefficient and/or loss to improve a match of the antenna to the transmission line via holes placed around the circumference of the absorbing material.
A build plate assembly for a three-dimensional printer comprising: a lighting panel having individually addressable pixels configured to selectively emit light and/or transmit light from illumination below the pixels to a top surface of the lighting panel; a rigid, optically transparent, gas-impermeable planar base having an upper surface and a lower surface that is affixed to the top surface of the lighting panel; a flexible, optically transparent, gas-permeable sheet having upper and lower surfaces, the upper surface comprising a build surface for forming a three-dimensional object, the sheet lower surface positioned opposite the base, wherein the build plate assembly is configured to permit gas flow to the build surface, and wherein the lighting panel is a grey scale lighting panel; wherein the base upper surface and/or the sheet lower surface have a surface topology forming a channel layer that increases gas flow to the gas permeable sheet; the build plate assembly further comprising an adhesive layer between the gas-permeable sheet and the base; wherein the adhesive layer comprises a poly(dimethylsiloxane), PDMS, film. a lighting panel having individually addressable pixels configured to selectively emit light and/or transmit light from illumination below the pixels to a top surface of the lighting panel; a rigid, optically transparent, gas-impermeable planar base having an upper surface and a lower surface that is affixed to the top surface of the lighting panel; a flexible, optically transparent, gas-permeable sheet having upper and lower surfaces, the upper surface comprising a build surface for forming a three-dimensional object, the sheet lower surface positioned opposite the base, wherein the build plate assembly is configured to permit gas flow to the build surface, and wherein the lighting panel is a grey scale lighting panel; wherein the base upper surface and/or the sheet lower surface have a surface topology forming a channel layer that increases gas flow to the gas permeable sheet; the build plate assembly further comprising an adhesive layer between the gas-permeable sheet and the base; wherein the adhesive layer comprises a poly(dimethylsiloxane), PDMS, film.
A hydrocarbon soluble metal composition comprising of reaction products of a metal source, a lipophilic phenolic acid, a surfactant and an organophosphorus compound and is having formula: MLxQyPz, wherein: M is a metal source; L is a ligand selected from the group containing lipophilic phenolic acid; x ranges from 0.5 to 2; Q is a surfactant selected from the group containing quaternary ammonium phosphonium salt and combination thereof; y ranges from 0.5 to 1.5; P is an organophosphorus compound; and z ranges from 0.5 to 1.5; wherein the metal source is salt of metal selected from the group consisting of vanadium (V), molybdenum (Mo), tungsten (W) and combinations thereof; wherein the organophosphorus compound is selected from the group consisting of organophosphine, organophosphine oxide, organophosphinite, organophosphonite, organophosphinate, organophosphite, organophosphonate, organophosphate and organophosphoramidate, organic trithiophosphites, organic thiophosphates, triphenylphosphine sulfide, triphenylphosphine selenide, triphenylphosphine phenylimide, and combinations thereof. M is a metal source; L is a ligand selected from the group containing lipophilic phenolic acid; x ranges from 0.5 to 2; Q is a surfactant selected from the group containing quaternary ammonium phosphonium salt and combination thereof; y ranges from 0.5 to 1.5; P is an organophosphorus compound; and z ranges from 0.5 to 1.5; wherein the metal source is salt of metal selected from the group consisting of vanadium (V), molybdenum (Mo), tungsten (W) and combinations thereof; wherein the organophosphorus compound is selected from the group consisting of organophosphine, organophosphine oxide, organophosphinite, organophosphonite, organophosphinate, organophosphite, organophosphonate, organophosphate and organophosphoramidate, organic trithiophosphites, organic thiophosphates, triphenylphosphine sulfide, triphenylphosphine selenide, triphenylphosphine phenylimide, and combinations thereof.
A light comprising - a light head having a light source arranged therein, - a holding element , wherein the light head is mounted rotatably about an axis of rotation (D) on the holding element , wherein the light head has a pivot pin and the holding element has two receiving jaws which are arranged to encompass the pivot pin so that the pivot pin is arranged so as to be rotationally movable about the axis of rotation (D) relative to the receiving jaws , characterized in that the light furthermore has a spring element which is arranged to encompass the two receiving jaws in such a way that it compresses the receiving jaws in order to inhibit the rotational mobility of the pivot pin . - a light head having a light source arranged therein, - a holding element , wherein the light head is mounted rotatably about an axis of rotation (D) on the holding element ,
A game board comprising: a field plate ; a rod-shaped manipulation lever disposed under the field plate ; and a player figure which is disposed above the field plate and make a play on a ball located on the field plate , wherein the field plate has a long through-hole , wherein the player figure is attached to the manipulation lever through the through-hole , wherein the player figure is movable above the field plate as the manipulation lever is moved in its axial direction, and is rotatable about a pivot portion of the player figure by a rotation manipulation on the manipulation lever , characterised in that the field plate has, beside the through-hole , a ball holding portion to allow the ball to stay, and wherein part of the player figure is capable of coming into contact with the ball staying in the ball holding portion. a field plate ; a rod-shaped manipulation lever disposed under the field plate ; and a player figure which is disposed above the field plate and make a play on a ball located on the field plate , wherein the field plate has a long through-hole , wherein the player figure is attached to the manipulation lever through the through-hole , wherein the player figure is movable above the field plate as the manipulation lever is moved in its axial direction, and is rotatable about a pivot portion of the player figure by a rotation manipulation on the manipulation lever , characterised in that the field plate has, beside the through-hole , a ball holding portion to allow the ball to stay, and wherein part of the player figure is capable of coming into contact with the ball staying in the ball holding portion.
Riding surface having a tread layer and a mat which is arranged between a base and the tread layer , wherein the tread layer substantially comprises sand with aggregates and drip tubes for watering the tread layer are preferably embedded in grooves at the side of the mat facing the tread layer , characterised in that the mat is produced from a solid material, whereby a pressure distribution is ensured and the tread layer is positioned directly on the mat and the drip tubes so that the volume of the tread layer is minimised.
A staple cartridge for use with a surgical stapling instrument, said staple cartridge comprising: a cartridge body , comprising: a deck ; staple cavities defined in said deck; a longitudinal slot defined in said deck and 2. configured to receive a tissue cutting member of the surgical stapling instrument; recesses defined in said deck; and a trough defined in said deck and connecting said recesses sensors positioned in said recesses, wherein said sensors are attached to said cartridge body; a conductive trace electrically connecting said sensors, wherein said conductive trace is positioned in said trough; and staples removably stored in said staple cavities, wherein said staples are ejected from said staple cavities during a staple firing stroke produced by the surgical stapling instrument. a deck ; staple cavities defined in said deck; a longitudinal slot defined in said deck and 2. configured to receive a tissue cutting member of the surgical stapling instrument; recesses defined in said deck; and a trough defined in said deck and connecting said recesses sensors positioned in said recesses, wherein said sensors are attached to said cartridge body; a conductive trace electrically connecting said sensors, wherein said conductive trace is positioned in said trough; and staples removably stored in said staple cavities, wherein said staples are ejected from said staple cavities during a staple firing stroke produced by the surgical stapling instrument.
A compound, or a pharmaceutically acceptable salt thereof, of formula (I): wherein R 1 is selected from H, C 1-6 alkyl, C 1-6 alkylamino, C 1-6 alkoxy, C 3-6 cycloalkylC 1-6 alkyl, C 3-6 cycloalkylC 1-6 alkylamino, C 3-6 cycloalkylC 1-6 alkoxy, C 1-6 alkoxyC 1-6 alkyl, C 1-6 alkoxyC 1-6 alkylamino and C 1-6 alkoxyC 1-6 alkoxy; wherein the C 1-6 alkyl, C 1-6 alkylamino, C 1-6 alkoxy, C 3-6 cycloalkylC 1-6 alkyl, C 3-6 cycloalkylC 1-6 alkylamino, C 3-6 cycloalkylC 1-6 alkoxy, C 1-6 alkoxyC 1-6 alkyl, C 1-6 alkoxyC 1-6 alkylamino or C 1-6 alkoxyC 1-6 alkoxy is branched or unbranched and optionally terminally substituted with a hydroxyl, amino, thio, hydrazino, hydrazido, azido, acetylenyl, carboxyl, or maleimido group; Z is selected from C 2 -C 6 alkyl and C 2 -C 6 alkenyl, wherein the C 2 -C 6 alkyl or C 2 -C 6 alkenyl is unsubstituted or terminally substituted by -(O-C 2 -C 6 alkyl) l-6 -; X is O or S; n is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20; R 2 is H or a straight or branched, optionally unsaturated, C 4 -C 24 alkyl, or a straight or branched, optionally unsaturated, C 4 -C 24 , acyl; R 3 is a straight or branched, optionally unsaturated, C 4 -C 24 alkyl or a straight or branched, optionally unsaturated, C 4 -C 24 acyl. R 1 is selected from H, C 1-6 alkyl, C 1-6 alkylamino, C 1-6 alkoxy, C 3-6 cycloalkylC 1-6 alkyl, C 3-6 cycloalkylC 1-6 alkylamino, C 3-6 cycloalkylC 1-6 alkoxy, C 1-6 alkoxyC 1-6 alkyl, C 1-6 alkoxyC 1-6 alkylamino and C 1-6 alkoxyC 1-6 alkoxy; wherein the C 1-6 alkyl, C 1-6 alkylamino, C 1-6 alkoxy, C 3-6 cycloalkylC 1-6 alkyl, C 3-6 cycloalkylC 1-6 alkylamino, C 3-6 cycloalkylC 1-6 alkoxy, C 1-6 alkoxyC 1-6 alkyl, C 1-6 alkoxyC 1-6 alkylamino or C 1-6 alkoxyC 1-6 alkoxy is branched or unbranched and optionally terminally substituted with a hydroxyl, amino, thio, hydrazino, hydrazido, azido, acetylenyl, carboxyl, or maleimido group; Z is selected from C 2 -C 6 alkyl and C 2 -C 6 alkenyl, wherein the C 2 -C 6 alkyl or C 2 -C 6 alkenyl is unsubstituted or terminally substituted by -(O-C 2 -C 6 alkyl) l-6 -; X is O or S; n is 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20; R 2 is H or a straight or branched, optionally unsaturated, C 4 -C 24 alkyl, or a straight or branched, optionally unsaturated, C 4 -C 24 , acyl; R 3 is a straight or branched, optionally unsaturated, C 4 -C 24 alkyl or a straight or branched, optionally unsaturated, C 4 -C 24 acyl.