mhurhangee/patent-ind-claim-en huggingface dataset:
A tympanostomy tube placement device comprising: a stem connected to a deployment mechanism or having a coupler for connection to a deployment mechanism; a needle having a tip configured to pierce a tympanic membrane, the needle having a longitudinal axis; and a tympanostomy tube comprising a proximal flange , an interlumen connector , and a distal flange , characterized in that , the device further comprises a retainer comprising a plurality of fingers extending axially and being at a distance from said longitudinal axis; the retainer is movable from a pre-deployment distal position at which it is adapted to press radially inwardly against the tube distal flange to retain said distal flange in an axially folded position, to a deployment proximal position at which the tube distal flange is free to spring out radially to a deployed position, and the tube proximal flange comprises passageways , and in a pre-deployment position the retainer fingers extend through the proximal flange passageways and press the tube distal flange inwardly. a stem connected to a deployment mechanism or having a coupler for connection to a deployment mechanism; a needle having a tip configured to pierce a tympanic membrane, the needle having a longitudinal axis; and a tympanostomy tube comprising a proximal flange , an interlumen connector , and a distal flange , characterized in that , the device further comprises a retainer comprising a plurality of fingers extending axially and being at a distance from said longitudinal axis; the retainer is movable from a pre-deployment distal position at which it is adapted to press radially inwardly against the tube distal flange to retain said distal flange in an axially folded position, to a deployment proximal position at which the tube distal flange is free to spring out radially to a deployed position, and the tube proximal flange comprises passageways , and in a pre-deployment position the retainer fingers extend through the proximal flange passageways and press the tube distal flange inwardly.
A process for producing the roll-up type capacitor which comprises the following steps of: forming a sacrificial layer on a substrate ; forming a lower electrode layer , a dielectric layer and an upper electrode layer on the sacrificial layer in this order to obtain a stack of layers; rolling-up the stack by removing the sacrificial layer to obtain a cylindrical part ; and forming a first external electrode on one side of the obtained cylindrical part such that the first external electrode is electrically connected to the upper electrode layer , and forming a second external electrode on the other side such that the second external electrode is electrically connected to the lower electrode layer . forming a sacrificial layer on a substrate ; forming a lower electrode layer , a dielectric layer and an upper electrode layer on the sacrificial layer in this order to obtain a stack of layers; rolling-up the stack by removing the sacrificial layer to obtain a cylindrical part ; and forming a first external electrode on one side of the obtained cylindrical part such that the first external electrode is electrically connected to the upper electrode layer , and forming a second external electrode on the other side such that the second external electrode is electrically connected to the lower electrode layer .
A bispecific antibody comprising a first binding part specifically binding to human CEACAM5 and a second binding part specifically binding to human CD47 characterized in that : a) the first binding part comprises as heavy chain variable region a heavy chain variable region comprising a CDRH1 of SEQ ID NO:1, a CDRH2 of SEQ ID NO:2 and a CDRH3 of SEQ ID NO:3, b) the first binding part comprises as light chain variable region a light chain variable region comprising a CDRL set selected from the group consisting of a CDRL1 of SEQ ID NO:17, CDRL2 of SEQ ID NO:18, and CDRL3 of SEQ ID NO:19, or a CDRL1 of SEQ ID NO:23, CDRL2 of SEQ ID NO:24, and CDRL3 of SEQ ID NO:25, and c) the second binding part comprises as heavy chain variable region a heavy chain variable region comprising a CDRH1 of SEQ ID NO:1, a CDRH2 of SEQ ID NO:2 and a CDRH3 of SEQ ID NO:3, and as light chain variable region a light chain variable region comprising a CDRL1 of SEQ ID NO:7, a CDRL2 of SEQ ID NO:8, and a CDRL3 of SEQ ID NO:9. a) the first binding part comprises as heavy chain variable region a heavy chain variable region comprising a CDRH1 of SEQ ID NO:1, a CDRH2 of SEQ ID NO:2 and a CDRH3 of SEQ ID NO:3, b) the first binding part comprises as light chain variable region a light chain variable region comprising a CDRL set selected from the group consisting of a CDRL1 of SEQ ID NO:17, CDRL2 of SEQ ID NO:18, and CDRL3 of SEQ ID NO:19, or a CDRL1 of SEQ ID NO:23, CDRL2 of SEQ ID NO:24, and CDRL3 of SEQ ID NO:25, and a CDRL1 of SEQ ID NO:17, CDRL2 of SEQ ID NO:18, and CDRL3 of SEQ ID NO:19, or a CDRL1 of SEQ ID NO:23, CDRL2 of SEQ ID NO:24, and CDRL3 of SEQ ID NO:25, and c) the second binding part comprises as heavy chain variable region a heavy chain variable region comprising a CDRH1 of SEQ ID NO:1, a CDRH2 of SEQ ID NO:2 and a CDRH3 of SEQ ID NO:3, and as light chain variable region a light chain variable region comprising a CDRL1 of SEQ ID NO:7, a CDRL2 of SEQ ID NO:8, and a CDRL3 of SEQ ID NO:9.
An alkylated 3-hydroxydiphenylamine of formula II: wherein x is 0, 1 or 2 and y is 1, 2 or 3; each R is independently C 4-24 alkyl or C 4-24 alkyl substituted by one or more hydroxyl and/or interrupted by one or more oxygen atom, or two adjacent R groups together with the carbons to which they are attached form a 5 to 8 member heterocyclic ring or a 6 to 8 member non-aromatic carbocyclic ring, which heterocyclic or non-aromatic carbocyclic ring is optionally substituted by alkyl, hydroxyl or alkoxy; at least one carbon atom adjacent to the amine nitrogen is unsubstituted; and wherein the total number of carbon atoms of the combined groups R is 12 or higher. each R is independently C 4-24 alkyl or C 4-24 alkyl substituted by one or more hydroxyl and/or interrupted by one or more oxygen atom, or two adjacent R groups together with the carbons to which they are attached form a 5 to 8 member heterocyclic ring or a 6 to 8 member non-aromatic carbocyclic ring, which heterocyclic or non-aromatic carbocyclic ring is optionally substituted by alkyl, hydroxyl or alkoxy; at least one carbon atom adjacent to the amine nitrogen is unsubstituted; and wherein the total number of carbon atoms of the combined groups R is 12 or higher.
Rechargeable lithium battery cell having a housing, a positive electrode, a negative electrode, and an electrolyte which is based on SO 2 and contains a conducting salt, wherein the positive electrode contains LiFePO 4 as active material, characterised in that the electrolyte contains at least 2 mol SO 2 per mol conducting salt.
Aircraft area comprising: - an interior component ; - a textile display disposed on the interior component and including at least one textile fiber capable of changing a color at at least one section of the textile fiber ; - a controller operatively coupled to the textile display and configured to change the color of the at least one section of the textile fiber , such that the textile display displays information; and - a personal input unit configured to receive user inputs and operatively connected to the controller , wherein the personal input unit is integrated into the textile display . - an interior component ; - a textile display disposed on the interior component and including at least one textile fiber capable of changing a color at at least one section of the textile fiber ; - a controller operatively coupled to the textile display and configured to change the color of the at least one section of the textile fiber , such that the textile display displays information; and - a personal input unit configured to receive user inputs and operatively connected to the controller , wherein the personal input unit is integrated into the textile display .
A method of protecting a monument during manufacturing of a vehicle, the method comprising: attaching a plurality of brackets to the monument prior to installation in the vehicle, each of the plurality of brackets having corresponding fasteners facing outwardly relative to the monument ; connecting a blanket to the corresponding fasteners ; installing the monument in the vehicle ; disconnecting the blanket ; and removing the plurality of brackets from the monument . attaching a plurality of brackets to the monument prior to installation in the vehicle, each of the plurality of brackets having corresponding fasteners facing outwardly relative to the monument ; connecting a blanket to the corresponding fasteners ; installing the monument in the vehicle ; disconnecting the blanket ; and removing the plurality of brackets from the monument .
A method for diagnosing triple-negative breast cancer (TNBC) in a patient comprising the step of: determining the level of at least one miRNA representative for triple-negative breast cancer in a blood cellular fraction from the patient, wherein the at least one miRNA is selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 23, and a sequence having at least 80% sequence identity thereto. determining the level of at least one miRNA representative for triple-negative breast cancer in a blood cellular fraction from the patient, wherein the at least one miRNA is selected from the group consisting of SEQ ID NO: 1 to SEQ ID NO: 23, and a sequence having at least 80% sequence identity thereto.
A fluid management system for providing fluid from a fluid source to the body of a patient, including: a compressible chamber having an inlet end and an outlet end ; a fluid conduit in fluid communication with the fluid source and with an interior of the compressible chamber ; characterised by a bypass conduit having an inlet end in fluid communication with the fluid source and an outlet end adapted for providing fluid to a trocar , the bypass conduit passing either through or around the compressible chamber from the inlet end to the outlet end thereof; a first one way valve adapted to admit fluid from the fluid conduit into the interior of the compressible chamber and a second one way valve adapted to admit fluid within the interior of the compressible chamber into the bypass conduit ; wherein a portion of the bypass conduit upstream of the second one way valve is adapted to be collapsible under the force of selectively applied external pressure when the compressible chamber is at least partially filled with fluid from the fluid source , so as to selectively close off the bypass conduit upstream of the second one way valve . a compressible chamber having an inlet end and an outlet end ; a fluid conduit in fluid communication with the fluid source and with an interior of the compressible chamber ; characterised by a bypass conduit having an inlet end in fluid communication with the fluid source and an outlet end adapted for providing fluid to a trocar , the bypass conduit passing either through or around the compressible chamber from the inlet end to the outlet end thereof; a first one way valve adapted to admit fluid from the fluid conduit into the interior of the compressible chamber and a second one way valve adapted to admit fluid within the interior of the compressible chamber into the bypass conduit ; wherein a portion of the bypass conduit upstream of the second one way valve is adapted to be collapsible under the force of selectively applied external pressure when the compressible chamber is at least partially filled with fluid from the fluid source , so as to selectively close off the bypass conduit upstream of the second one way valve .
Machine for the feeding of quadrupeds and in particular of calves, comprising a load-bearing frame , on which there are mounted: - motorized means for sliding on the ground, for the movement of said load-bearing frame ; - a first group configured for the automatic dispensing of solid feed, said first group comprising a first hopper for a solid feed with an upper loading opening and a bottom with an outlet opening , said first group comprising lifting means configured to lift said solid feed from said outlet opening to a discharge chute ; - a second group comprising a suction nozzle , said second group being configured for preparing and making available a feeding liquid by means of said suction nozzle ; characterized in that said discharge chute is telescopic, and is actuated by a corresponding actuator . - motorized means for sliding on the ground, for the movement of said load-bearing frame ; - a first group configured for the automatic dispensing of solid feed, said first group comprising a first hopper for a solid feed with an upper loading opening and a bottom with an outlet opening , said first group comprising lifting means configured to lift said solid feed from said outlet opening to a discharge chute ; - a second group comprising a suction nozzle , said second group being configured for preparing and making available a feeding liquid by means of said suction nozzle ;
A computer-implemented method for analyzing tread surface data to assess one or more parameters of a tread of a tire , comprising: obtaining a tread surface map for the tread of the tire , the tread surface map comprising a plurality of data points, each data point providing a tread height for the tread of the tire ; processing , with a computing device , the tread surface map to generate a convex hull , the convex hull being a three-dimensional shell that wraps the tread surface map, the convex hull being convex at all points around the convex hull ; determining , with the computing device , a relative tread depth map based at least in part on the tread surface map and the convex hull , the relative tread depth map being determined as the difference between the convex hull and the tread surface map ; and analyzing the relative tread depth map to assess one or more parameters of the tread of the tire ; wherein the method comprises modifying the tread surface map prior to processing the tread surface map to generate the convex hull ; wherein modifying the tread surface map prior to processing the tread surface map to generate a convex hull comprises extending the tread surface map in the circumferential direction at both circumferential ends of the initial tread surface map , wherein the extensions at each circumferential end includes data points of the opposite circumferential end. obtaining a tread surface map for the tread of the tire , the tread surface map comprising a plurality of data points, each data point providing a tread height for the tread of the tire ; processing , with a computing device , the tread surface map to generate a convex hull , the convex hull being a three-dimensional shell that wraps the tread surface map, the convex hull being convex at all points around the convex hull ; determining , with the computing device , a relative tread depth map based at least in part on the tread surface map and the convex hull , the relative tread depth map being determined as the difference between the convex hull and the tread surface map ; and analyzing the relative tread depth map to assess one or more parameters of the tread of the tire ; wherein the method comprises modifying the tread surface map prior to processing the tread surface map to generate the convex hull ; wherein modifying the tread surface map prior to processing the tread surface map to generate a convex hull comprises extending the tread surface map in the circumferential direction at both circumferential ends of the initial tread surface map , wherein the extensions at each circumferential end includes data points of the opposite circumferential end.
Compound of formula (I): where R 1 , R 2 , R 3 , R 4 are - (C 1 -C 12 ) -aryl.
Exhaust gas purification system for an internal combustion engine , having an exhaust system which is connectable to an outlet of the internal combustion engine , wherein the exhaust system comprises an exhaust gas channel in which, in the flow direction of an exhaust of the internal combustion engine through the exhaust gas channel , a particle filter is arranged proximal to the engine as a first emission-reducing component; a first three-way catalytic converter is arranged downstream of the particle filter , likewise in a position proximal to the engine; and a further three-way catalytic converter is arranged downstream of the first three-way catalytic converter ; wherein an exhaust gas burner is arranged downstream of the particle filter , with which burner hot exhaust can be introduced into the exhaust system to heat at least one of the three-way catalytic converters .
A wireless detonation system , comprising: a blasting operation device disposed at a distanced from a blasting target , the blasting operation device being configured to wirelessly transmit a first downstream signal at a first frequency; a detonator loaded in a blast hole of the blasting target, characterised in that , the detonator including an explosive-side receiving antenna configured to wirelessly receive a second downstream signal at a second frequency lower than the first frequency; and a relay device including a first receiving antenna configured to wirelessly receive the first downstream signal, a relay processor configured to process the wirelessly received first downstream signal and configured to process the second downstream signal to be wirelessly transmitted at the second frequency, and a second transmitting antenna configured to wirelessly transmit the second downstream signal, wherein the second transmitting antenna is positioned within an insertion hole of the blasting target, the insertion hole being aligned with the blast hole . a blasting operation device disposed at a distanced from a blasting target , the blasting operation device being configured to wirelessly transmit a first downstream signal at a first frequency; a detonator loaded in a blast hole of the blasting target, characterised in that , the detonator including an explosive-side receiving antenna configured to wirelessly receive a second downstream signal at a second frequency lower than the first frequency; and a relay device including a first receiving antenna configured to wirelessly receive the first downstream signal, a relay processor configured to process the wirelessly received first downstream signal and configured to process the second downstream signal to be wirelessly transmitted at the second frequency, and a second transmitting antenna configured to wirelessly transmit the second downstream signal, wherein the second transmitting antenna is positioned within an insertion hole of the blasting target, the insertion hole being aligned with the blast hole .
A system for producing high pressure extracorporeal ballistic shockwaves , the system comprising: at least one high pressure ballistic shockwave applicator , comprising a projectile accelerating portion and at least one shockwave generating portion ; said shockwave is generated by a collision between an accelerated projectile disposed within said projectile accelerating portion against a shockwave generating surface disposed in said shockwave generating portion ; said shockwave generating surface is configured to withstand high pressure ballistic impact with said projectile ; wherein said shockwave generating portion comprises said shockwave generating surface that is configured to withstand high pressure ballistic impact with said projectile ; a focal surface configured for shaping the generated shockwaves according to required treatment parameters; and a shockwave propagating medium provided for propagating the shockwave from the focal surface onto a treatment area through a membrane ; the system further comprising a gaseous high pressure source and a high pressure flow controller to energize and accelerate said projectile in a controllable and directed manner; the system characterized in that said gaseous high pressure source and high pressure flow controller _is configured to provide an operational pressure of up to about 100 bar, wherein said operational pressure is utilized to accelerate said projectile ; wherein said projectile generates a shockwave having an intensity of from about 20 Joules up to about 80Joules (J). at least one high pressure ballistic shockwave applicator , comprising a projectile accelerating portion and at least one shockwave generating portion ; said shockwave is generated by a collision between an accelerated projectile disposed within said projectile accelerating portion against a shockwave generating surface disposed in said shockwave generating portion ; said shockwave generating surface is configured to withstand high pressure ballistic impact with said projectile ; wherein said shockwave generating portion comprises said shockwave generating surface that is configured to withstand high pressure ballistic impact with said projectile ; a focal surface configured for shaping the generated shockwaves according to required treatment parameters; and a shockwave propagating medium provided for propagating the shockwave from the focal surface onto a treatment area through a membrane ; the system further comprising a gaseous high pressure source and a high pressure flow controller to energize and accelerate said projectile in a controllable and directed manner; the system characterized in that said gaseous high pressure source and high pressure flow controller _is configured to provide an operational pressure of up to about 100 bar, wherein said operational pressure is utilized to accelerate said projectile ; wherein said projectile generates a shockwave having an intensity of from about 20 Joules up to about 80Joules (J).
A control and/or a regulating device , configured for controlling or regulating a medical blood treatment apparatus for performing a method to remove blood and/or a blood mixture from an extracorporeal blood circuit used for blood treatment of a patient with a blood filter after completion of a blood treatment session during a reinfusion process, wherein the blood filter comprises a blood chamber and a dialysate chamber , between which a membrane is arranged, wherein for blood treatment, the blood chamber is connected to an arterial blood line leading to the blood chamber and to a venous blood line leading away from the blood chamber as well as to a dialysis fluid inlet line leading to the dialysate chamber and to a dialysate outlet line leading away from the dialysate chamber , the method comprising the following step of: - displacing the blood and/or the blood mixture from the blood chamber by introducing substituate into the arterial blood line under formation of a blood-substituate mixture; and characterized by the step of: - generating a pressure difference in the blood filter with a lower pressure in the dialysate chamber and a higher pressure in the blood chamber during the reinfusion process for removing water from the blood-substituate mixture via the blood filter . - displacing the blood and/or the blood mixture from the blood chamber by introducing substituate into the arterial blood line under formation of a blood-substituate mixture; and - generating a pressure difference in the blood filter with a lower pressure in the dialysate chamber and a higher pressure in the blood chamber during the reinfusion process for removing water from the blood-substituate mixture via the blood filter .