Compounds of the formula Ia or Ib in which R 1 denotes H, Het, Ar, (CH 2 ) n OH, 1-methylsulfonyl-cycloprop-1-yl, CONH 2 , CONHA, CONA 2 , Cyc, OA or CH(A)SO 2 A, R 2 denotes H, A, (CH 2 ) n Ar, (CH 2 ) n Cyc or (CH 2 ) n Het, R 3 denotes H or A, Het denotes denotes a mono- or bicyclic aromatic, unsaturated or saturated heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono-, di- or trisubstituted by NH 2 , NHA, NA 2 , COOH, COOA, CONH 2 , CONHA, CONA 2 , CONHAr, CN, OH, (CH 2 ) n Ar 1 , O(CH 2 ) n Ar 1 , A, SOA, SO 2 A, Hal, =NH and/or =O, Ar denotes phenyl, napthyl or biphenyl, each of which is unsubstituted or mono-, di- or trisubstituted by NH 2 , NHA, NA 2 , COOH, COOA, CONH 2 , CONHA, CONA 2 , NHCOA, CHO, COA, SO 3 H, SO 2 NH 2 , O(CH 2 ) p NH 2 , (CH 2 ) n Het 1 , O(CH 2 ) n Het 1 , (CH 2 ) n Ar 1 , O(CH 2 ) n Ar 1 , O(CH 2 ) p CONH 2 , O(CH 2 ) p NHCOA, Hal, SOA, S(=O, =NH)A, SO 2 A, A, CN and/or (CH 2 ) n OH, Ar 1 denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, A, OH and/or OA, Het 1 denotes a mono- or bicyclic aromatic, unsaturated or saturated heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono-, di- or trisubstituted by Hal, A, COOA, NH 2 , NHA and/or NA 2 , A denotes unbranched or branched alkyl having 1-6 C-atoms, in which 1-7 H atoms may be replaced by OH, F, Cl and/or Br and/or in which one or two non-adjacent CH 2 groups may be replaced by O and/or NH groups, Cyc denotes cyclic alkyl with 3, 4, 5, 6 or 7 C-atoms, Hal denotes F, Cl, Br or I, n denotes 0, 1, 2, 3 or 4, p denotes 1, 2, 3 or 4, and pharmaceutically acceptable salts, tautomers and stereoisomers thereof, including mixtures thereof in all ratios. R 1 denotes H, Het, Ar, (CH 2 ) n OH, 1-methylsulfonyl-cycloprop-1-yl, CONH 2 , CONHA, CONA 2 , Cyc, OA or CH(A)SO 2 A, R 2 denotes H, A, (CH 2 ) n Ar, (CH 2 ) n Cyc or (CH 2 ) n Het, R 3 denotes H or A, Het denotes denotes a mono- or bicyclic aromatic, unsaturated or saturated heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono-, di- or trisubstituted by NH 2 , NHA, NA 2 , COOH, COOA, CONH 2 , CONHA, CONA 2 , CONHAr, CN, OH, (CH 2 ) n Ar 1 , O(CH 2 ) n Ar 1 , A, SOA, SO 2 A, Hal, =NH and/or =O, Ar denotes phenyl, napthyl or biphenyl, each of which is unsubstituted or mono-, di- or trisubstituted by NH 2 , NHA, NA 2 , COOH, COOA, CONH 2 , CONHA, CONA 2 , NHCOA, CHO, COA, SO 3 H, SO 2 NH 2 , O(CH 2 ) p NH 2 , (CH 2 ) n Het 1 , O(CH 2 ) n Het 1 , (CH 2 ) n Ar 1 , O(CH 2 ) n Ar 1 , O(CH 2 ) p CONH 2 , O(CH 2 ) p NHCOA, Hal, SOA, S(=O, =NH)A, SO 2 A, A, CN and/or (CH 2 ) n OH, Ar 1 denotes phenyl which is unsubstituted or mono-, di- or trisubstituted by Hal, A, OH and/or OA, Het 1 denotes a mono- or bicyclic aromatic, unsaturated or saturated heterocycle having 1 to 4 N, O and/or S atoms, which may be unsubstituted or mono-, di- or trisubstituted by Hal, A, COOA, NH 2 , NHA and/or NA 2 , A denotes unbranched or branched alkyl having 1-6 C-atoms, in which 1-7 H atoms may be replaced by OH, F, Cl and/or Br and/or in which one or two non-adjacent CH 2 groups may be replaced by O and/or NH groups, Cyc denotes cyclic alkyl with 3, 4, 5, 6 or 7 C-atoms, Hal denotes F, Cl, Br or I, n denotes 0, 1, 2, 3 or 4, p denotes 1, 2, 3 or 4, <EOS>