mhurhangee/patent-ind-claim-en huggingface dataset:
A beverage machine comprising: a liquid supply tank configured to hold a liquid for forming a beverage; a pump fluidly coupled to the liquid supply tank ; a liquid supply line configured to provide liquid from the liquid supply tank to the pump ; the beverage machine being characterized by a vent fluidly coupled to the liquid supply line to vent at least a portion of the liquid supply line to ambient pressure such that, for at least some fill levels of the liquid supply tank , a liquid level in the liquid supply line is at a same height as a liquid level in the liquid supply tank ; and a sensor configured to detect presence and absence of liquid in the liquid supply line . a liquid supply tank configured to hold a liquid for forming a beverage; a pump fluidly coupled to the liquid supply tank ; a liquid supply line configured to provide liquid from the liquid supply tank to the pump ; the beverage machine being characterized by a vent fluidly coupled to the liquid supply line to vent at least a portion of the liquid supply line to ambient pressure such that, for at least some fill levels of the liquid supply tank , a liquid level in the liquid supply line is at a same height as a liquid level in the liquid supply tank ; and a sensor configured to detect presence and absence of liquid in the liquid supply line .
Applicator for applying an application material, in particular for applying a damping material, a sealing material or adhesive, grease, oil, silicone or a spray film, in particular for seam sealing on a flanged seam of a component, in particular a motor vehicle bodywork component, having a) a base element , in particular for mounting on an application robot for movable positioning and orientation of the applicator by the application robot, or for mounting on a stationary stand, b) a nozzle head with at least one outlet nozzle for the delivery of the application material through the outlet nozzle, c) a rotary drive , which is supported on the base element and acts upon the nozzle head , d) an eccentric which is rotated by the rotary drive and acts on the nozzle head , so that the nozzle head carries out an eccentric movement relative to the base element , and e) a torque bracket (20-23) which is supported on one side against the nozzle head and on the other side against the base element , so that the torque bracket (20-23) prevents a rotation movement of the nozzle head , characterised in that the torque bracket (20-23) comprises the following: f) a rod which is mounted on the nozzle head and is oriented transversely to the rotation axis of the rotary drive , and g) a rod guide which is mounted on the base element and guides the rod displaceably. a) a base element , in particular for mounting on an application robot for movable positioning and orientation of the applicator by the application robot, or for mounting on a stationary stand, b) a nozzle head with at least one outlet nozzle for the delivery of the application material through the outlet nozzle, c) a rotary drive , which is supported on the base element and acts upon the nozzle head , d) an eccentric which is rotated by the rotary drive and acts on the nozzle head , so that the nozzle head carries out an eccentric movement relative to the base element , and e) a torque bracket (20-23) which is supported on one side against the nozzle head and on the other side against the base element , so that the torque bracket (20-23) prevents a rotation movement of the nozzle head , f) a rod which is mounted on the nozzle head and is oriented transversely to the rotation axis of the rotary drive , and g) a rod guide which is mounted on the base element and guides the rod displaceably.
Motor vehicle lock for a motor vehicle door arrangement , wherein a lock latch and a pawl assigned to the lock latch are provided, wherein the lock latch can be brought into an open position and into a closed position, wherein the lock latch in the closed position is or can be brought into engagement with a striker or the like, wherein the pawl can be brought into an engaged position in which it fixes the lock latch in the closed position and wherein the pawl can be lifted out into a release position in which it releases the lock latch , wherein the pawl can be brought into the release position by means of an actuating arrangement , wherein a crash element is provided which, in order to avoid a crash-induced lifting-out of the pawl , can be adjusted by the crash-induced deformation of said component by a component of the motor vehicle door arrangement , in particular a door outer skin , into a crash position, and in that, for this purpose, the crash element in the crash position blocks the pawl wherein a crash element mounting is provided which is configured as a linear guide and in which the crash element is displaceably guided.
A method for identifying functionally interacting amino acid residues in a protein of interest, said method comprising: a. obtaining a first library of single mutation variants of said protein of interest by single-site saturation mutagenesis, wherein said each variant contains an amino acid substitution at a single residue position, and at least 70% of each possible amino acid substitution at each residue position of said protein of interest is represented in said first library; b. identifying a first subpopulation of variants from the first library, wherein said first subpopulation comprises a population enriched in single amino acid substitution variants, each of which decreases the activity of said protein of interest compared to wild-type levels; c. introducing at least five mutations at different residue positions from said first subpopulation singly in to each variant of the first library to obtain a second library of variants having two or one amino acid substitution in said protein of interest; d. identifying a second subpopulation from said second library, comprising variants, each of which has two amino acid substitutions in said protein of interest; e. identifying a third subpopulation, which is a subset of the said second subpopulation of said second library, wherein in each variant of said third subpopulation, the mutation as identified from each variant of said first library suppresses the altered activity of the variant of the first subpopulation, wherein the two substituted amino acids in each variant of the said third subpopulation are indicative that the two amino acids at corresponding positions in wild-type said protein of interest are functionally interacting. a. obtaining a first library of single mutation variants of said protein of interest by single-site saturation mutagenesis, wherein said each variant contains an amino acid substitution at a single residue position, and at least 70% of each possible amino acid substitution at each residue position of said protein of interest is represented in said first library; b. identifying a first subpopulation of variants from the first library, wherein said first subpopulation comprises a population enriched in single amino acid substitution variants, each of which decreases the activity of said protein of interest compared to wild-type levels; c. introducing at least five mutations at different residue positions from said first subpopulation singly in to each variant of the first library to obtain a second library of variants having two or one amino acid substitution in said protein of interest; d. identifying a second subpopulation from said second library, comprising variants, each of which has two amino acid substitutions in said protein of interest; e. identifying a third subpopulation, which is a subset of the said second subpopulation of said second library, wherein in each variant of said third subpopulation, the mutation as identified from each variant of said first library suppresses the altered activity of the variant of the first subpopulation,
A wireless field device assembly comprising: a process sensor configured to monitor a process variable and produce a sensor signal; a housing enclosing an interior space of the wireless field device ; a transmitter enclosed within the interior space, and configured to process the sensor signal; and a power module configured to be housed in the interior space, the power module comprising: an energy storage device ; a connection to a local power source ; and a processor configured to provide the transmitter with a diagnostic report of the energy storage device and the local power source , wherein the power module further comprises first and second voltage sensors configured to sense first and second output voltages of the energy storage device and the local power source , respectively; wherein the diagnostic report comprises an identification of at least one of the energy storage device and the local power source ; wherein the identification of at least one of the energy storage device and the local power source comprises an identification of the local power source based on the first and second output voltages. a process sensor configured to monitor a process variable and produce a sensor signal; a housing enclosing an interior space of the wireless field device ; a transmitter enclosed within the interior space, and configured to process the sensor signal; and a power module configured to be housed in the interior space, the power module comprising: an energy storage device ; a connection to a local power source ; and a processor configured to provide the transmitter with a diagnostic report of the energy storage device and the local power source , wherein the power module further comprises first and second voltage sensors configured to sense first and second output voltages of the energy storage device and the local power source , respectively; wherein the diagnostic report comprises an identification of at least one of the energy storage device and the local power source ; wherein the identification of at least one of the energy storage device and the local power source comprises an identification of the local power source based on the first and second output voltages. an energy storage device ; a connection to a local power source ; and a processor configured to provide the transmitter with a diagnostic report of the energy storage device and the local power source , wherein the power module further comprises first and second voltage sensors configured to sense first and second output voltages of the energy storage device and the local power source , respectively; wherein the diagnostic report comprises an identification of at least one of the energy storage device and the local power source ; wherein the identification of at least one of the energy storage device and the local power source comprises an identification of the local power source based on the first and second output voltages.
A power cable assembly for transferring high voltage alternating current over long distances, comprising a plurality of power cables where each power cable comprises a core , a conductor and a cable insulation , the power cable assembly further comprising shunt inductances connected to each conductor at regular intervals along the conductors , characterised in that the cables are continuous.
A polypropylene composition comprising: a first polymer phase comprising a polypropylene polymer, the polypropylene polymer having a xylene soluble content of less than 10% by weight and having a melt flow rate of from 20 g/10 min to 50 g/10 min; and a second polymer phase combined with the first polymer phase, the second polymer phase comprising a propylene and alpha olefin copolymer; and wherein the polypropylene composition has a melt flow rate of 3 g/10 min or greater, and wherein the ratio of the melt flow rate of the first polymer phase to the melt flow rate of the polypropylene composition is greater than or equal to 1, the polypropylene composition having a xylene soluble portion and a xylene insoluble portion, the polypropylene composition having a total xylene soluble content of from 12% to 25% by weight, the xylene soluble portion containing the alpha olefin in an amount from 55% to 70% by weight, the xylene insoluble portion containing the alpha olefin in an amount from 15% to 40% by weight, the polypropylene composition having a Gardner impact strength at -20°C of greater than 200 inch-lbs (22.6 J); wherein the melt flow rates are measured in accordance with the ASTM D 1238 test method at 230°C with a 2.16 kg weight for propylene-based polymers, and the Gardner impact strength is measured in accordance with ASTM D5420. a first polymer phase comprising a polypropylene polymer, the polypropylene polymer having a xylene soluble content of less than 10% by weight and having a melt flow rate of from 20 g/10 min to 50 g/10 min; and a second polymer phase combined with the first polymer phase, the second polymer phase comprising a propylene and alpha olefin copolymer; and wherein the polypropylene composition has a melt flow rate of 3 g/10 min or greater, and wherein the ratio of the melt flow rate of the first polymer phase to the melt flow rate of the polypropylene composition is greater than or equal to 1, the polypropylene composition having a xylene soluble portion and a xylene insoluble portion, the polypropylene composition having a total xylene soluble content of from 12% to 25% by weight, the xylene soluble portion containing the alpha olefin in an amount from 55% to 70% by weight, the xylene insoluble portion containing the alpha olefin in an amount from 15% to 40% by weight, the polypropylene composition having a Gardner impact strength at -20°C of greater than 200 inch-lbs (22.6 J); wherein the melt flow rates are measured in accordance with the ASTM D 1238 test method at 230°C with a 2.16 kg weight for propylene-based polymers, and the Gardner impact strength is measured in accordance with ASTM D5420.
A toy system comprising - a toy spinning top ; and - a toy figurine , wherein said toy spinning top comprises a spinner body with an elongate axis (A); a sidewall ; and a bottom wall , wherein said sidewall of the spinner body comprises a top rim ; an outside surface ; and an inside surface , wherein said bottom wall comprises an outside bottom surface ; and an inside bottom surface , characterized in that the inner bottom surface comprises first connection means for releasably connecting second connection means of said toy figurine to the toy spinning top, and allowing transfer of torque from said toy figurine to said toy spinning top ; and wherein said sidewall has a height (h1) from said inner bottom surface to said top rim which extends over a major part of the height of said toy figurine . - a toy spinning top ; and - a toy figurine , wherein said toy spinning top comprises a spinner body with an elongate axis (A); a sidewall ; and a bottom wall , wherein said sidewall of the spinner body comprises a top rim ; an outside surface ; and an inside surface , wherein said bottom wall comprises an outside bottom surface ; and an inside bottom surface , characterized in that the inner bottom surface comprises first connection means for releasably connecting second connection means of said toy figurine to the toy spinning top, and allowing transfer of torque from said toy figurine to said toy spinning top ; and wherein said sidewall has a height (h1) from said inner bottom surface to said top rim which extends over a major part of the height of said toy figurine .
Heat exchanger comprising at least two plates overlapping and reciprocally joined to each other in correspondence with respective coupling surfaces , and in which, between said coupling surfaces , at least one passage channel for a heat-carrying fluid is made, by deforming at least one of said plates , wherein said plates are joined to each other by means of heating and rolling in correspondence with respective coupling surfaces by means of the Roll Bond technique, characterized in that it comprises at least one hole made through through only one of said plates in order to intercept said channel , and a tubular connection element which is connected to said hole in an angled direction with respect to said plates to allow the passage of said heat-carrying fluid through said channel .
A method for producing a 3D item by means of fused deposition modelling using a fused deposition modeling 3D printer , the method comprising a 3D printing stage comprising layer-wise depositing core-shell-shell material via a printer nozzle on a receiver item , wherein the core-shell-shell material comprises a hollow tube comprising a hollow core and a first shell enclosing the hollow core , and 3D printable material at least partly enclosing the first shell , to provide the 3D item comprising a core-shell-shell layer , wherein the core-shell-shell layer comprises the hollow tube comprising the hollow core and the first shell enclosing the hollow core , and 3D printed material at least partly enclosing the first shell , characterized in that the first shell comprises a first shell material having a first glass transition temperature Tg1, the 3D printable material has a second glass transition temperature Tg2, and Tg2<Tg1, wherein the method comprises 3D printing the 3D printable material with a printer nozzle temperature lower than the first glass transition temperature Tg1 and higher than the second glass transition temperature Tg2, and wherein the method further comprises a cutting stage comprising temporarily heating the printer nozzle to a temperature above the first glass transition temperature Tg1. the first shell comprises a first shell material having a first glass transition temperature Tg1, the 3D printable material has a second glass transition temperature Tg2, and Tg2<Tg1, wherein the method comprises 3D printing the 3D printable material with a printer nozzle temperature lower than the first glass transition temperature Tg1 and higher than the second glass transition temperature Tg2, and wherein the method further comprises a cutting stage comprising temporarily heating the printer nozzle to a temperature above the first glass transition temperature Tg1.
An oral care device configured to assess a health parameter of gingival tissue of a user, the oral care device comprising: a force-generating module configured to apply a momentary force to the gingival tissue by applying a burst of compressed air or a burst of liquid to the gingival tissue; a sensor configured to obtain a plurality of optical signals from the gingival tissue over time after the momentary force has been applied; a controller configured to quantify, based at least in part on an analysis of the plurality of optical signals, a health parameter of the gingival tissue, wherein the health parameter is based at least in part on an amount of time the gingival tissue takes to recover to the application of force; and a feedback module configured to provide information to the user regarding the quantified health parameter. a force-generating module configured to apply a momentary force to the gingival tissue by applying a burst of compressed air or a burst of liquid to the gingival tissue; a sensor configured to obtain a plurality of optical signals from the gingival tissue over time after the momentary force has been applied; a controller configured to quantify, based at least in part on an analysis of the plurality of optical signals, a health parameter of the gingival tissue, wherein the health parameter is based at least in part on an amount of time the gingival tissue takes to recover to the application of force; and a feedback module configured to provide information to the user regarding the quantified health parameter.
A method, implemented at a computer system that includes one or more processors and system memory, of quantifying a nucleic acid sample comprising nucleic acid of two or more contributors, the method comprising: (a) extracting nucleic acid molecules from the nucleic acid sample; (b) amplifying the extracted nucleic acid molecules; (c) sequencing the amplified nucleic acid molecules using a nucleic acid sequencer to produce nucleic acid sequence reads; (d) mapping, by the one or more processors, the nucleic acid sequence reads to one or more polymorphism loci on a reference sequence; (e) determining, using the mapped nucleic acid sequence reads and by the one or more processors, allele counts of nucleic acid sequence reads for one or more alleles at the one or more polymorphism loci; and (f) quantifying, using a probabilistic mixture model and by the one or more processors, one or more fractions of nucleic acid of the two or more contributors in the nucleic acid sample, wherein using the probabilistic mixture model comprises applying a probabilistic mixture model to the allele counts of nucleic acid sequence reads, and wherein the probabilistic mixture model uses probability distributions to model the allele counts of nucleic acid sequence reads at the one or more polymorphism loci, the probability distributions accounting for errors in the nucleic acid sequence reads, wherein the two or more contributors comprise one or more donors of a transplant and a donee of the transplant, and wherein the nucleic acid sample comprises a sample obtained from the donee. (a) extracting nucleic acid molecules from the nucleic acid sample; (b) amplifying the extracted nucleic acid molecules; (c) sequencing the amplified nucleic acid molecules using a nucleic acid sequencer to produce nucleic acid sequence reads; (d) mapping, by the one or more processors, the nucleic acid sequence reads to one or more polymorphism loci on a reference sequence; (e) determining, using the mapped nucleic acid sequence reads and by the one or more processors, allele counts of nucleic acid sequence reads for one or more alleles at the one or more polymorphism loci; and (f) quantifying, using a probabilistic mixture model and by the one or more processors, one or more fractions of nucleic acid of the two or more contributors in the nucleic acid sample, wherein using the probabilistic mixture model comprises applying a probabilistic mixture model to the allele counts of nucleic acid sequence reads, and wherein the probabilistic mixture model uses probability distributions to model the allele counts of nucleic acid sequence reads at the one or more polymorphism loci, the probability distributions accounting for errors in the nucleic acid sequence reads,
A method of quantifying whether an adhesive agent leaks from a polarizing plate or a degree of leakage of the adhesive agent, the method comprising: (a) preparing a polarizing plate including an adhesive layer ; (b) providing the polarizing plate so that one end of the polarizing plate adjoins a guide unit ; (c) moving the polarizing plate on the guide unit; (d) measuring frictional force applied between the polarizing plate and the guide unit while moving the polarizing plate; and (e) deriving, based on the measured value of the frictional force, a determination criterion based on which whether the adhesive agent leaks from the polarizing plate or the degree of leakage of the adhesive agent is determined. (a) preparing a polarizing plate including an adhesive layer ; (b) providing the polarizing plate so that one end of the polarizing plate adjoins a guide unit ; (c) moving the polarizing plate on the guide unit; (d) measuring frictional force applied between the polarizing plate and the guide unit while moving the polarizing plate; and (e) deriving, based on the measured value of the frictional force, a determination criterion based on which whether the adhesive agent leaks from the polarizing plate or the degree of leakage of the adhesive agent is determined.
A method for reducing the viscosity of a liquid pharmaceutical formulation comprising a therapeutic protein at a concentration of at least 70 mg/ml, comprising the step of combining the therapeutic protein with a viscosity-reducing concentration of an excipient selected from the group consisting of the n-acetyl arginine, n-acetyl lysine, n-acetyl histidine, n-acetyl proline and mixtures thereof.