mhurhangee/patent-ind-claim-en huggingface dataset:
An aerosolization device for providing aerosolized medicament to a user, the aerosolization device comprising: a mouthpiece end by which a user may cause an inspiratory flow through a conduit ; an aerosol generator leading in to the conduit which includes a vibratable mesh ; a fluid receiving chamber leading into the aerosol generator for receiving a volume of a liquid medicament, wherein the fluid receiving chamber comprises a tapered chamber having a top opening and a smaller base opening for directing liquid medicament onto the vibratable mesh for aerosolization; an outer housing ; and a top cover over the top opening of the fluid receiving chamber, wherein the top cover defines an opening which provides fluid access to the fluid receiving chamber, characterised in that the top cover comprises a set of spokes which extend outwardly from the opening and extend beyond the top opening thereby to seat the top cover over the outer housing. a mouthpiece end by which a user may cause an inspiratory flow through a conduit ; an aerosol generator leading in to the conduit which includes a vibratable mesh ; a fluid receiving chamber leading into the aerosol generator for receiving a volume of a liquid medicament, wherein the fluid receiving chamber comprises a tapered chamber having a top opening and a smaller base opening for directing liquid medicament onto the vibratable mesh for aerosolization; an outer housing ; and a top cover over the top opening of the fluid receiving chamber, wherein the top cover defines an opening which provides fluid access to the fluid receiving chamber, characterised in that the top cover comprises a set of spokes which extend outwardly from the opening and extend beyond the top opening thereby to seat the top cover over the outer housing.
An apparatus , comprising: a first arbiter circuit associated with a first memory device ; a second arbiter circuit associated with a second memory device ; a resistor coupled in common to the first and second memory devices; characterized in that the first and second arbiter circuits are configured to use the resistor in an arbitration protocol that provides the first memory device access to the resistor in the event that the first and second arbiter circuits concurrently attempt to take control of the resistor for use in, respectively, a first calibration operation and a second calibration operation, wherein the first arbiter circuit is configured to sink a first amount of current from the resistor, causing the voltage at the resistor to sink below a second threshold voltage, to take control of the resistor for use by the a calibration circuit in response to a voltage at the resistor being equal to or above a first threshold voltage when executing the arbitration protocol, wherein, in executing the arbitration protocol, the second arbiter circuit is configured to sink a second amount of current from the resistor responsive to the voltage at the resistor being equal to or above a first threshold voltage, and to take control of the resistor for use by a second calibration circuit responsive to the voltage at the resistor being equal to or above the second threshold voltage. a first arbiter circuit associated with a first memory device ; a second arbiter circuit associated with a second memory device ; a resistor coupled in common to the first and second memory devices; characterized in that the first and second arbiter circuits are configured to use the resistor in an arbitration protocol that provides the first memory device access to the resistor in the event that the first and second arbiter circuits concurrently attempt to take control of the resistor for use in, respectively, a first calibration operation and a second calibration operation, wherein the first arbiter circuit is configured to sink a first amount of current from the resistor, causing the voltage at the resistor to sink below a second threshold voltage, to take control of the resistor for use by the a calibration circuit in response to a voltage at the resistor being equal to or above a first threshold voltage when executing the arbitration protocol, wherein, in executing the arbitration protocol, the second arbiter circuit is configured to sink a second amount of current from the resistor responsive to the voltage at the resistor being equal to or above a first threshold voltage, and to take control of the resistor for use by a second calibration circuit responsive to the voltage at the resistor being equal to or above the second threshold voltage.
A mold-clamping machine comprising: a stationary mount which is fastened to a base and which supports a stationary mold ; a movable mount which is mounted on the base so as to be movable, and which supports a movable mold ; a mold-clamping mechanism which is placed outwardly relative to the movable mount , is mounted on the base so as to be movable, and clamps the movable mold with the stationary mold ; a tie bar that extends so as to pass completely through at least the movable mount ; and a mold opening-and-closing mechanism that moves either one of the movable mount or the mold-clamping mechanism along the tie bar relative to the stationary mount , wherein the mold-clamping machine further comprises a constraining mechanism that causes the mold-clamping mechanism to be in a constrained state relative to the tie bar , wherein the constraining mechanism comprises a magnet mechanism that changes the mold-clamping mechanism to be in the constrained state or in an unconstrained state relative to the tie bar , and characterized in that the constraining mechanism comprises a cylindrical portion which encircles the tie bar , extends from the mold-clamping mechanism so as to pass completely through the movable mount , and has a tip protruding from the movable mount toward the stationary mount . a stationary mount which is fastened to a base and which supports a stationary mold ; a movable mount which is mounted on the base so as to be movable, and which supports a movable mold ; a mold-clamping mechanism which is placed outwardly relative to the movable mount , is mounted on the base so as to be movable, and clamps the movable mold with the stationary mold ; a tie bar that extends so as to pass completely through at least the movable mount ; and a mold opening-and-closing mechanism that moves either one of the movable mount or the mold-clamping mechanism along the tie bar relative to the stationary mount , wherein the mold-clamping machine further comprises a constraining mechanism that causes the mold-clamping mechanism to be in a constrained state relative to the tie bar , wherein the constraining mechanism comprises a magnet mechanism that changes the mold-clamping mechanism to be in the constrained state or in an unconstrained state relative to the tie bar , and characterized in that the constraining mechanism comprises a cylindrical portion which encircles the tie bar , extends from the mold-clamping mechanism so as to pass completely through the movable mount , and has a tip protruding from the movable mount toward the stationary mount .
A latex dispersion comprising: polychloroprene, and, a vulcanization composition comprising: elemental sulfur, a single fugitive xanthate accelerator selected from the group consisting of diisopropyl xanthogen polysulfide, dibutyl xanthogen disulfide, and diisopropyl xanthogen disulfide, and a metal oxide selected from the group consisting of zinc oxide, magnesium oxide, lead oxide and combinations thereof in a range from 6 to 12 parts by dry weight rubber, wherein the composition does not include any additional compounds that function as accelerators for vulcanizing elastomers. polychloroprene, and, a vulcanization composition comprising: elemental sulfur, a single fugitive xanthate accelerator selected from the group consisting of diisopropyl xanthogen polysulfide, dibutyl xanthogen disulfide, and diisopropyl xanthogen disulfide, and a metal oxide selected from the group consisting of zinc oxide, magnesium oxide, lead oxide and combinations thereof in a range from 6 to 12 parts by dry weight rubber, wherein the composition does not include any additional compounds that function as accelerators for vulcanizing elastomers. elemental sulfur, a single fugitive xanthate accelerator selected from the group consisting of diisopropyl xanthogen polysulfide, dibutyl xanthogen disulfide, and diisopropyl xanthogen disulfide, and a metal oxide selected from the group consisting of zinc oxide, magnesium oxide, lead oxide and combinations thereof in a range from 6 to 12 parts by dry weight rubber, wherein the composition does not include any additional compounds that function as accelerators for vulcanizing elastomers.
A method of providing a metal seal in a subsurface borehole , the method comprising: transporting from surface in a fluid and/or a conduit material/s for sealing operation/s into the borehole; wherein the material/s comprise a metal for forming the metal seal and are transported in a non-unified indefinite form as a multiplicity of elements, with the metal being transported in particulate form to the portion of the borehole to be sealed; forming the metal seal in situ in a portion of the borehole from or by a unification of the multiplicity of elements of the material/s , the multiplicity of elements being discrete prior to formation of the seal; wherein the metal seal comprises an undefined or indefinite geometry prior to forming the seal in the borehole ; wherein the method comprises heating the metal and/or other material/s to a seal-forming temperature, without the temperature exceeding a seal-forming threshold temperature; wherein the seal-forming threshold temperature is determined by a material property of a material in or forming the borehole ; and wherein the borehole comprises a polymer with a baking temperature; and the method comprises ensuring the seal-forming threshold temperature is sufficiently lower than the polymer baking temperature to ensure no risk of the polymer undesirably reaching its baking temperature. transporting from surface in a fluid and/or a conduit material/s for sealing operation/s into the borehole; wherein the material/s comprise a metal for forming the metal seal and are transported in a non-unified indefinite form as a multiplicity of elements, with the metal being transported in particulate form to the portion of the borehole to be sealed; forming the metal seal in situ in a portion of the borehole from or by a unification of the multiplicity of elements of the material/s , the multiplicity of elements being discrete prior to formation of the seal; wherein the metal seal comprises an undefined or indefinite geometry prior to forming the seal in the borehole ; wherein the method comprises heating the metal and/or other material/s to a seal-forming temperature, without the temperature exceeding a seal-forming threshold temperature; wherein the seal-forming threshold temperature is determined by a material property of a material in or forming the borehole ; and wherein the borehole comprises a polymer with a baking temperature; and the method comprises ensuring the seal-forming threshold temperature is sufficiently lower than the polymer baking temperature to ensure no risk of the polymer undesirably reaching its baking temperature.
An optical impedance sensor comprising: a tube having an internal volume; a first light guide comprising a first optical fiber ; and a second light guide comprising a second optical fiber spaced apart from said first optical fiber , wherein said first optical fiber and said second optical fiber are placed inside said tube , and wherein said first optical fiber and said second optical fiber are substantially parallel, characterised in that at least one of said first and second optical fibers is encased by a tube which comprises a jacket having a longitudinal slot , said encased optical fiber comprising a cladding having a non-uniform surface in an area bounded by said longitudinal slot of said jacket ; and the other of said first and second optical fibers comprises a cladding having a non-uniform surface in an area confronting said longitudinal slot of said jacket of said encased optical fiber . a tube having an internal volume; a first light guide comprising a first optical fiber ; and a second light guide comprising a second optical fiber spaced apart from said first optical fiber , wherein said first optical fiber and said second optical fiber are placed inside said tube , and wherein said first optical fiber and said second optical fiber are substantially parallel, characterised in that at least one of said first and second optical fibers is encased by a tube which comprises a jacket having a longitudinal slot , said encased optical fiber comprising a cladding having a non-uniform surface in an area bounded by said longitudinal slot of said jacket ; and the other of said first and second optical fibers comprises a cladding having a non-uniform surface in an area confronting said longitudinal slot of said jacket of said encased optical fiber .
A CMOS image sensor comprising at least one pixel comprising: a photodiode having a first terminal connected to a node of application of a first reference potential (GND); a first MOS transistor connecting a second terminal of the photodiode to a sense node (SN) of the pixel; a second MOS transistor connecting the sense node (SN) to a node of application of a second reference potential (VDDH); and a third MOS transistor assembled as a source follower having its gate connected to the sense node (SN) and having its source intended to be connected to a readout circuit, the first , second , and third transistors having a same gate insulator thickness, wherein the third transistor has a gate length smaller than the gate lengths of the first and second transistors and/or a gate width smaller than the gate widths of the first and second transistors, wherein the difference between the first (GND) and second (VDDH) reference potentials is greater than the maximum voltage which may be applied between two terminals of the third MOS transistor , and wherein the body region or the drain region of the third transistor is connected to a node of application of a third reference potential (VL) between the first (GND) and second (VDDH) potentials. a photodiode having a first terminal connected to a node of application of a first reference potential (GND); a first MOS transistor connecting a second terminal of the photodiode to a sense node (SN) of the pixel; a second MOS transistor connecting the sense node (SN) to a node of application of a second reference potential (VDDH); and a third MOS transistor assembled as a source follower having its gate connected to the sense node (SN) and having its source intended to be connected to a readout circuit, the first , second , and third transistors having a same gate insulator thickness, wherein the third transistor has a gate length smaller than the gate lengths of the first and second transistors and/or a gate width smaller than the gate widths of the first and second transistors, wherein the difference between the first (GND) and second (VDDH) reference potentials is greater than the maximum voltage which may be applied between two terminals of the third MOS transistor , and wherein the body region or the drain region of the third transistor is connected to a node of application of a third reference potential (VL) between the first (GND) and second (VDDH) potentials.
A fusion protein comprising the cell-penetrating peptide derived from the HIV Tat protein (Tat) with the caspase activation and recruitment domain (CARD) from the Apoptosis-associated speck-like protein containing a CARD (ASC) gene (TatCARD protein) for use in the prevention, amelioration, or treatment of an ocular disease associated with oxidative stress or inflammation.
A process for producing a copolymer, comprising: contacting at least one isoolefin monomer with at least one multiolefin and/or β-pinene monomer in the presence of at least one Lewis acid and at least one initiator in a diluent comprising a tetrafluorinated propene selected from 2,3,3,3-tetrafluoro-1-propene (HFO-1234yf), 1,1,3,3-tetrafluoro-1-propene, 1,1,2,3-tetrafluoro-1-propene, 1,2,3,3-tetrafluoro-1-propene or mixtures thereof.
System for linear optical sampling and coherent detection of an optical signal comprising - a source able to emit a pulsed optical signal, - an input able to receive an optical signal, - at least a first optical hybrid circuit and a second hybrid circuit , - a device comprising balanced photodetectors (23A-23D) and an analogue-digital converter , characterized in that it further comprises - an optical coupler able to divide the pulsed optical signal into two replicas, the first replica of the pulsed optical signal is dispatched to said first optical hybrid circuit and the second replica of the pulsed optical signal is dispatched to said second optical hybrid circuit , - an optical coupler able to divide the incoming optical signal into two replicas, the first replica of the incoming optical signal is dispatched to said first optical hybrid circuit and the second replica of the incoming optical signal is dispatched to a wavelength recovery apparatus , whose output is a continuous-wave optical signal at the central wavelength of the incoming optical signal, which dispatches it to said second optical hybrid circuit , - the balanced photodetectors (23A-23D) being able to detect the optical signals at the output of the two optical hybrid circuits . - a source able to emit a pulsed optical signal, - an input able to receive an optical signal, - at least a first optical hybrid circuit and a second hybrid circuit , - a device comprising balanced photodetectors (23A-23D) and an analogue-digital converter , - an optical coupler able to divide the pulsed optical signal into two replicas, the first replica of the pulsed optical signal is dispatched to said first optical hybrid circuit and the second replica of the pulsed optical signal is dispatched to said second optical hybrid circuit , - an optical coupler able to divide the incoming optical signal into two replicas, the first replica of the incoming optical signal is dispatched to said first optical hybrid circuit and the second replica of the incoming optical signal is dispatched to a wavelength recovery apparatus , whose output is a continuous-wave optical signal at the central wavelength of the incoming optical signal, which dispatches it to said second optical hybrid circuit , - the balanced photodetectors (23A-23D) being able to detect the optical signals at the output of the two optical hybrid circuits .
An aligning device for aligning at least one rail for building tracks on permanent roadways, comprising a support block having a segment inside the track , a segment outside the track , and a rail receptacle , a first lifting unit comprising a first central axis (Z1) and implemented for lifting the support block in the direction of the first central axis (Z1), a second lifting unit comprising a second central axis (Z2) and implemented for lifting the support block in the direction of the second central axis (Z2), the support block comprising a transverse axis (Q) substantially perpendicular to the first central axis (Z1), and the rail receptacle comprising a support surface for a rail foot and enclosing a permanently preset setting angle (α) with the transverse axis (Q), the rail receptacle being disposed rigidly between the segment inside the track and the segment outside the track , the first lifting unit being disposed in the segment inside the track of the support block , and the second lifting unit being disposed in the segment outside the track of the support block , the rail receptacle being implemented as a recess in the support block , characterized by a clamping device disposed on a side outside the track and implemented for applying a clamping force (F) in a first clamping direction (R1) acting parallel to the transverse axis (Q) in the direction of the segment inside the track , and a second clamping device (R2) acting in the direction of the support surface , on a rail received in the rail receptacle . a support block having a segment inside the track , a segment outside the track , and a rail receptacle , a first lifting unit comprising a first central axis (Z1) and implemented for lifting the support block in the direction of the first central axis (Z1), a second lifting unit comprising a second central axis (Z2) and implemented for lifting the support block in the direction of the second central axis (Z2), the support block comprising a transverse axis (Q) substantially perpendicular to the first central axis (Z1), and the rail receptacle comprising a support surface for a rail foot and enclosing a permanently preset setting angle (α) with the transverse axis (Q), the rail receptacle being disposed rigidly between the segment inside the track and the segment outside the track , the first lifting unit being disposed in the segment inside the track of the support block , and the second lifting unit being disposed in the segment outside the track of the support block , the rail receptacle being implemented as a recess in the support block , characterized by a clamping device disposed on a side outside the track and implemented for applying a clamping force (F) in a first clamping direction (R1) acting parallel to the transverse axis (Q) in the direction of the segment inside the track , and a second clamping device (R2) acting in the direction of the support surface , on a rail received in the rail receptacle .
Process for preparing rivaroxaban or a pharmaceutically acceptable salt or solvate thereof comprising the following steps: a) dissolving rivaroxaban in a solvent or a mixture of solvents b) crystallization of rivaroxaban c) washing and drying the crystals and d) obtaining pure rivaroxaban wherein pure rivaroxaban has a purity at least 99,0 area % as determined by HPLC, wherein the crystallization according to b) is achieved either by (i) decreasing the temperature of a rivaroxaban crystallization mixture comprising rivaroxaban and a solvent from a temperature between room temperature and the reflux temperature of the solvent to a temperature within the range -20 °C to 40 °C, (ii) the addition of an anti-solvent to a solution of rivaroxaban in a solvent, or (iii) the addition of a solution of rivaroxaban in a solvent to an anti-solvent, the solvent from step (i) being selected from 2-butanone, 3-pentanone, acetonitrile, 1-butanol and mixtures thereof, and the solvent from steps (ii) and (iii) being selected from DMSO, DMF, DMA, acetic acid or mixtures thereof. a) dissolving rivaroxaban in a solvent or a mixture of solvents b) crystallization of rivaroxaban c) washing and drying the crystals and d) obtaining pure rivaroxaban (i) decreasing the temperature of a rivaroxaban crystallization mixture comprising rivaroxaban and a solvent from a temperature between room temperature and the reflux temperature of the solvent to a temperature within the range -20 °C to 40 °C, (ii) the addition of an anti-solvent to a solution of rivaroxaban in a solvent, or (iii) the addition of a solution of rivaroxaban in a solvent to an anti-solvent,