mhurhangee/patent-ind-claim-en huggingface dataset:
A thermal sensing system comprising: an electrical contact including a shaft that defines a channel , the channel extending into the shaft from an opening along an outer surface of the shaft ; and a sensing element disposed at least partially outside of the channel and operably connected to the channel through the opening , characterised in that : the sensing element is configured to move relative to the electrical contact based on a temperature change within the channel ; and the thermal sensing system further comprises a non-contact position sensor spaced apart from the electrical contact and the sensing element , the position sensor being configured to detect a position change of a portion of the sensing element outside of the channel responsive to the temperature change within the channel . an electrical contact including a shaft that defines a channel , the channel extending into the shaft from an opening along an outer surface of the shaft ; and a sensing element disposed at least partially outside of the channel and operably connected to the channel through the opening , characterised in that : the sensing element is configured to move relative to the electrical contact based on a temperature change within the channel ; and the thermal sensing system further comprises a non-contact position sensor spaced apart from the electrical contact and the sensing element , the position sensor being configured to detect a position change of a portion of the sensing element outside of the channel responsive to the temperature change within the channel . the sensing element is configured to move relative to the electrical contact based on a temperature change within the channel ; and the thermal sensing system further comprises a non-contact position sensor spaced apart from the electrical contact and the sensing element , the position sensor being configured to detect a position change of a portion of the sensing element outside of the channel responsive to the temperature change within the channel .
A method for use in an analog front end component (210; 804) of a modem, the method comprising: receiving, by the analog front end component (210; 804), a digital modulated signal having a first frequency from a system on chip, SoC of the modem, wherein the digital modulated signal is synchronized with a master clock signal; remodulating the digital modulated signal to a remodulated signal having a target frequency by a remodulation circuitry (250; 350; 450; 550) of the analog front end component (210; 804), wherein the remodulated signal is synchronized with the master clock signal; and converting the remodulated signal to an analog output signal of the analog front end component by an analog-to-digital converter of the analog front end component (210; 804), the method further comprising: pre-correcting the digital modulated signal such that the first frequency is selected to compensate for frequency offset with respect to the master clock that is caused by the remodulating of the digital modulated signal, and determining the frequency offset using a demodulator (230; 630) in the SoC . receiving, by the analog front end component (210; 804), a digital modulated signal having a first frequency from a system on chip, SoC of the modem, wherein the digital modulated signal is synchronized with a master clock signal; remodulating the digital modulated signal to a remodulated signal having a target frequency by a remodulation circuitry (250; 350; 450; 550) of the analog front end component (210; 804), wherein the remodulated signal is synchronized with the master clock signal; and converting the remodulated signal to an analog output signal of the analog front end component by an analog-to-digital converter of the analog front end component (210; 804), the method further comprising: pre-correcting the digital modulated signal such that the first frequency is selected to compensate for frequency offset with respect to the master clock that is caused by the remodulating of the digital modulated signal, and determining the frequency offset using a demodulator (230; 630) in the SoC .
A pharmaceutical composition comprising as an active ingredient a compound of formula 1 wherein R 1 is H, C 1-6 -alkyl, C 0-4 -alkyl-C 3-6 -cycloalkyl, C 1-6 -haloalkyl; R 2 is H, C 1-6 -alkyl; X is an anion selected from the group consisting of chloride or 1⁄2 dibenzoyltartrate j is 1 or 2, and a first diluent, a second diluent, a binder, a disintegrant, and a lubricant and optionally a binder, wherein the pharmaceutical composition comprises 10-90% active ingredient 5-70% first diluent, 5-30% second diluent, 0-30% binder, 1-12% disintegrant, and 0.1-3% lubricant wherein the first and the second diluents are selected from the group consisting of cellulose powder, dibasic calciumphosphate anhydrous, dibasic calciumphosphate dihydrate, erythritol, low substituted hydroxypropyl cellulose, mannitol, pregelatinized starch or xylitol, wherein at least one of the first and the second diluent is dibasic calcium phosphate anhydrous, and wherein the pharmaceutical composition is in the dosage form of a film-coated tablet comprising 2-4% film coat for use in prevention or treatment of one of the following diseases: atopic dermatitis, ulcerative colitis, dermatitis, allergic contact dermatitis, and urticaria. R 1 is H, C 1-6 -alkyl, C 0-4 -alkyl-C 3-6 -cycloalkyl, C 1-6 -haloalkyl; R 2 is H, C 1-6 -alkyl; X is an anion selected from the group consisting of chloride or 1⁄2 dibenzoyltartrate j is 1 or 2, 10-90% active ingredient 5-70% first diluent, 5-30% second diluent, 0-30% binder, 1-12% disintegrant, and 0.1-3% lubricant
A method for visualizing an interaction between two nucleic acid sequences in a cell, the method comprising: a) contacting a prepared cell with a first nucleic acid probe comprising a first label and having complementarity to a first nucleic acid sequence and a second nucleic acid probe comprising a second label and having complementarity to a second nucleic acid sequence, wherein the prepared cell is fixed, permeabilized, and, optionally, comprises denatured chromosomal DNA and wherein the first and second labels are different and the first and second nucleic acid probes hybridize with the first and second nucleic acid sequences, respectively; b) contacting the cell from step a) with a first binding agent that binds to the first label and a second binding agent that binds to the second label; c) detecting the first and second binding agents by a proximity ligation assay to visualize the interaction between the two nucleic acid sequences in the cell. a) contacting a prepared cell with a first nucleic acid probe comprising a first label and having complementarity to a first nucleic acid sequence and a second nucleic acid probe comprising a second label and having complementarity to a second nucleic acid sequence, wherein the prepared cell is fixed, permeabilized, and, optionally, comprises denatured chromosomal DNA and wherein the first and second labels are different and the first and second nucleic acid probes hybridize with the first and second nucleic acid sequences, respectively; b) contacting the cell from step a) with a first binding agent that binds to the first label and a second binding agent that binds to the second label; c) detecting the first and second binding agents by a proximity ligation assay to visualize the interaction between the two nucleic acid sequences in the cell.
A device for recognizing an inscription on a tire , comprising: a driving surface plane ; at least one directional light source (61, 62, 63; 71, 72) which is configured to illuminate the tire ; at least one camera which is configured to record an image sequence comprising multiple images of a sidewall of a tire rolling on the driving surface plane ; an evaluation device which is configured, making use of the knowledge that individual points on the sidewall of the tire move along a cycloid during rolling, to determine movement of local image areas between two arbitrary images of the image sequence using an algorithm and to thus obtain parameters of the corresponding cycloid movement for each image area; and with the aid of the parameters thus determined, is configured to calculate the images of the image sequence back to an arbitrarily selected central image, and by fusion of the thus movement-compensated images, to synthesize a result image of the sidewall of the tire in which all edges of the inscription are represented with high contrast, and to evaluate the synthesized result image with the aid of a text recognition method. a driving surface plane ; at least one directional light source (61, 62, 63; 71, 72) which is configured to illuminate the tire ; at least one camera which is configured to record an image sequence comprising multiple images of a sidewall of a tire rolling on the driving surface plane ; an evaluation device which is configured, making use of the knowledge that individual points on the sidewall of the tire move along a cycloid during rolling, to determine movement of local image areas between two arbitrary images of the image sequence using an algorithm and to thus obtain parameters of the corresponding cycloid movement for each image area; and with the aid of the parameters thus determined, is configured to calculate the images of the image sequence back to an arbitrarily selected central image, and by fusion of the thus movement-compensated images, to synthesize a result image of the sidewall of the tire in which all edges of the inscription are represented with high contrast, and to evaluate the synthesized result image with the aid of a text recognition method.
A sanding tool , comprising: a machine body comprising a casing ; a battery pack disposed at a rear end of the machine body; a base plate assembly comprising a base plate ; a drive mechanism disposed in the casing and comprising a motor and an output shaft , wherein the motor has a motor shaft rotating around a first axis , the output shaft rotates around a second axis , and the output shaft transmits power to the base plate assembly to drive the base plate assembly to move; and a control mechanism electrically connected to the motor and configured to control the sanding tool to operate; wherein the battery pack and the motor are disposed on two sides of the output shaft, characterized in that the first axis and the second axis form an included angle and are not in a same plane. a machine body comprising a casing ; a battery pack disposed at a rear end of the machine body; a base plate assembly comprising a base plate ; a drive mechanism disposed in the casing and comprising a motor and an output shaft , wherein the motor has a motor shaft rotating around a first axis , the output shaft rotates around a second axis , and the output shaft transmits power to the base plate assembly to drive the base plate assembly to move; and a control mechanism electrically connected to the motor and configured to control the sanding tool to operate; wherein the battery pack and the motor are disposed on two sides of the output shaft, characterized in that the first axis and the second axis form an included angle and are not in a same plane.
A T cell therapy and an immunomodulatory compound for use in a method of treating cancer, wherein the method comprises: (a) administering a T cell therapy to a subject having a disease or condition that is cancer, wherein the T cell therapy is or comprises genetically engineered cells expressing a recombinant receptor that specifically binds to an antigen, wherein the recombinant receptor is a chimeric antigen receptor (CAR), and wherein the CAR comprises an extracellular domain comprising an antigen-binding domain that specifically binds to a tumor antigen, a spacer, and an intracellular signaling region; and (b) administering to the subject an immunomodulatory compound, wherein said immunomodulatory compound is thalidomide (2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3 -dione) or an analog or derivative of thalidomide, and wherein the immunomodulatory compound: (i) binds to cereblon (CRBN) and/or to the CRBN E3 ubiquitin-ligase complex, and (ii) enhances the degradation of both Ikaros (IKZF1) and Aiolos (IKZF3); wherein initiation of administration of the immunomodulatory compound is carried out 7 to 21 days after initiation of administration of the T cell therapy, and wherein the immunomodulatory compound is administered orally. (a) administering a T cell therapy to a subject having a disease or condition that is cancer, wherein the T cell therapy is or comprises genetically engineered cells expressing a recombinant receptor that specifically binds to an antigen, wherein the recombinant receptor is a chimeric antigen receptor (CAR), and wherein the CAR comprises an extracellular domain comprising an antigen-binding domain that specifically binds to a tumor antigen, a spacer, and an intracellular signaling region; and (b) administering to the subject an immunomodulatory compound, wherein said immunomodulatory compound is thalidomide (2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3 -dione) or an analog or derivative of thalidomide, and wherein the immunomodulatory compound: (i) binds to cereblon (CRBN) and/or to the CRBN E3 ubiquitin-ligase complex, and (ii) enhances the degradation of both Ikaros (IKZF1) and Aiolos (IKZF3); (i) binds to cereblon (CRBN) and/or to the CRBN E3 ubiquitin-ligase complex, and (ii) enhances the degradation of both Ikaros (IKZF1) and Aiolos (IKZF3); wherein initiation of administration of the immunomodulatory compound is carried out 7 to 21 days after initiation of administration of the T cell therapy, and wherein the immunomodulatory compound is administered orally.
Refrigerator and/or freezer , the refrigerator and/or freezer comprising a cabinet and at least one closure element closing an opening of the cabinet , a profile arrangement comprising at least one base , at least one fastening arrangement and at least one sealing arrangement , which has at least one hollow chamber produced from a flexible polymeric material having a Shore A hardness as defined by DIN ISO 868 of approximately 50 to 95, preferably 60 to 90, the profile arrangement having at least one functional element , the functional element being arranged in at least one hollow chamber of the sealing arrangement of the profile arrangement , the profile arrangement resting against the cabinet when the closure element is in the closed position around the opening of the refrigerator and/or freezer and sealing the gap between the closure element and the cabinet of the refrigerator and/or freezer , characterised in that the functional element is designed as a lighting element, the sealing arrangement is at least in part transparent or translucent and through the wall thickness thereof has a transmittance for visible light of approximately 50% to approximately 95%, preferably of approximately 60% to approximately 95%, measured in accordance with ISO 13468-2.
An electrical distribution circuit comprising: an input connectable to an AC source ; an output connectable to terminals of an electrical machine , the output configured to provide three-phase voltages and currents to the electrical machine ; and a diagnostic system configured to detect an excess voltage drop, in short EVD, in the electrical distribution circuit , the diagnostic system comprising a processor that is programmed to: receive measurements of the three-phase voltages and currents provided to the electrical machine ; compute a negative sequence voltage from the three-phase voltages and currents; determine a localization reference phase angle for each phase based in part on the three-phase voltages and currents; and calculate an EVD in the electrical distribution circuit based on the negative sequence voltage and the localization reference phase angles. an input connectable to an AC source ; an output connectable to terminals of an electrical machine , the output configured to provide three-phase voltages and currents to the electrical machine ; and a diagnostic system configured to detect an excess voltage drop, in short EVD, in the electrical distribution circuit , the diagnostic system comprising a processor that is programmed to: receive measurements of the three-phase voltages and currents provided to the electrical machine ; compute a negative sequence voltage from the three-phase voltages and currents; determine a localization reference phase angle for each phase based in part on the three-phase voltages and currents; and calculate an EVD in the electrical distribution circuit based on the negative sequence voltage and the localization reference phase angles. receive measurements of the three-phase voltages and currents provided to the electrical machine ; compute a negative sequence voltage from the three-phase voltages and currents; determine a localization reference phase angle for each phase based in part on the three-phase voltages and currents; and calculate an EVD in the electrical distribution circuit based on the negative sequence voltage and the localization reference phase angles.
An ultrasound imaging device, comprising: a housing comprising an outer surface and an inner surface, wherein the outer surface is configured to be grasped by a user; an array of acoustic elements configured to transmit ultrasound energy and receive ultrasound echoes associated with the ultrasound energy, wherein the array of acoustic elements is disposed at an end of the housing ; a heat sink disposed within the housing and configured to receive heat generated by the array of acoustic elements; a heat pipe disposed within the housing and configured to transmit the heat away from the end of the housing, wherein the heat pipe comprises a proximal portion and a distal portion ; and a heat spreader material disposed on the inner surface of the housing and configured to dissipate the heat, wherein the distal portion of the heat pipe is in thermal contact with the heat sink and the proximal portion of the heat pipe is in thermal contact with the heat spreader material, characterised in that the heat pipe comprises a central portion between the proximal portion and the distal portion, and wherein the proximal portion and the distal portion comprise a flattened cross-sectional profile with a larger surface area for thermal contact, and the central portion comprises a non-flattened cross-sectional profile with a smaller surface area for thermal contact. a housing comprising an outer surface and an inner surface, wherein the outer surface is configured to be grasped by a user; an array of acoustic elements configured to transmit ultrasound energy and receive ultrasound echoes associated with the ultrasound energy, wherein the array of acoustic elements is disposed at an end of the housing ; a heat sink disposed within the housing and configured to receive heat generated by the array of acoustic elements; a heat pipe disposed within the housing and configured to transmit the heat away from the end of the housing, wherein the heat pipe comprises a proximal portion and a distal portion ; and a heat spreader material disposed on the inner surface of the housing and configured to dissipate the heat, wherein the distal portion of the heat pipe is in thermal contact with the heat sink and the proximal portion of the heat pipe is in thermal contact with the heat spreader material, characterised in that the heat pipe comprises a central portion between the proximal portion and the distal portion, and wherein the proximal portion and the distal portion comprise a flattened cross-sectional profile with a larger surface area for thermal contact, and the central portion comprises a non-flattened cross-sectional profile with a smaller surface area for thermal contact.
A Fabry-Perot sensor comprising: a base ; a cavity formed between the base and a pressure sensitive diaphragm , and closed by the base and the pressure sensitive diaphragm; the pressure sensitive diaphragm fixed to the base, wherein the pressure sensitive diaphragm has at least one local areas , each of the at least one local areas has a doping substance doped into a base material of the pressure sensitive diaphragm to generate stresses, any of the at least one local areas does not extend the entire thickness of the pressure sensitive diaphragm, and the pressure sensitive diaphragm exhibits a wavy structure under the action of the stresses generated by doping; and a fiber optic configured to conduct a light signal, wherein one end of the fiber optic is fixed to a fiber optic mounting portion of the base, and the fiber optic mounting portion is located at an end of the base opposite the cavity. a base ; a cavity formed between the base and a pressure sensitive diaphragm , and closed by the base and the pressure sensitive diaphragm; the pressure sensitive diaphragm fixed to the base, wherein the pressure sensitive diaphragm has at least one local areas , each of the at least one local areas has a doping substance doped into a base material of the pressure sensitive diaphragm to generate stresses, any of the at least one local areas does not extend the entire thickness of the pressure sensitive diaphragm, and the pressure sensitive diaphragm exhibits a wavy structure under the action of the stresses generated by doping; and a fiber optic configured to conduct a light signal, wherein one end of the fiber optic is fixed to a fiber optic mounting portion of the base, and the fiber optic mounting portion is located at an end of the base opposite the cavity.
A gas turbine combustor comprising a fuel nozzle for injecting mixed gas of fuel and air, a cylindrical liner for burning and reacting the mixed gas of fuel and air in a combustion chamber , a transition piece which is a flow path for leading combustion gas generated in the liner to turbine blades, and a transition piece flow sleeve for wrapping an outside surface of the transition piece , wherein a plurality of first air introduction holes are formed in regions which are corner portions of the transition piece flow sleeve in a sectional direction thereof, and a plurality of second air introduction holes are formed in regions of the transition piece flow sleeve excluding the regions which are the corner portions of the transition piece flow sleeve in a sectional direction thereof, characterized in that a diameter of the first air introduction holes formed in the regions of the corner portions of the section of the transition piece flow sleeve is made smaller than a diameter of all of air introduction holes including the second air introduction holes formed in the regions of the transition piece flow sleeve excluding the regions of the corner portions .