A curable liquid silicone rubber composition comprising: (A) at least one organopolysiloxane A having at least two silicon-bonded alkenyl groups per molecule, said alkenyl groups each containing from 2 to 14 carbon atoms, preferably said alkenyl groups are chosen from the group consisting of vinyl, allyl, hexenyl, decenyl and tetradecenyl, and most preferably said alkenyl groups are vinyl groups, and (B) at least one organosilicon compound B having at least two and preferably at least three silicon-bonded hydrogen atoms per molecule, (C) at least one hydrosilylation catalyst C, and preferably at least one platinum-group metal catalyst C, and even more preferably hydrosilylation catalyst C is present in an amount such that the concentration is from 0.1 to 500 parts by weight of platinum-group metal, per million parts (ppm), based on the combined weight of ingredients (A) and (B), (D) eventually at least one filler D, and preferably the filler D is a surface treated silica, and even more preferably the filler D is a fumed silica in situ treated with hexamethyldisilazane and/or tetramethyldivinyldisilazane, (E) from 0.01% to 10 % by weight based on total weight of the curable liquid silicone rubber composition of a mixture M comprising at least one fatty acid ester G and at least one triazole compound E, (F) a therapeutically effective amount of at least one active pharmaceutical ingredient F comprising in its chemical structure at least one terminal alkene, at least one terminal alkyne or at least one terminal carbonyl, and wherein components (A) and (B) are present in an amount such that the molar ratio of silicon-bonded hydrogen atoms contained in components (B) to silicon-bonded alkenyl groups contained in component (A) ranges from 0.1 to 20, and preferably ranges from 0.25 to 5.0, and most preferably from 0.25 to 2.0, and (G) at least one cure rate controller G. (A) at least one organopolysiloxane A having at least two silicon-bonded alkenyl groups per molecule, said alkenyl groups each containing from 2 to 14 carbon atoms, preferably said alkenyl groups are chosen from the group consisting of vinyl, allyl, hexenyl, decenyl and tetradecenyl, and most preferably said alkenyl groups are vinyl groups, and (B) at least one organosilicon compound B having at least two and preferably at least three silicon-bonded hydrogen atoms per molecule, (C) at least one hydrosilylation catalyst C, and preferably at least one platinum-group metal catalyst C, and even more preferably hydrosilylation catalyst C is present in an amount such that the concentration is from 0.1 to 500 parts by weight of platinum-group metal, per million parts (ppm), based on the combined weight of ingredients (A) and (B), (D) eventually at least one filler D, and preferably the filler D is a surface treated silica, and even more preferably the filler D is a fumed silica in situ treated with hexamethyldisilazane and/or tetramethyldivinyldisilazane, (E) from 0.01% to 10 % by weight based on total weight of the curable liquid silicone rubber composition of a mixture M comprising at least one fatty acid ester G and at least one triazole compound E, (F) a therapeutically effective amount of at least one active pharmaceutical ingredient F comprising in its chemical structure at least one terminal alkene, at least one terminal alkyne or at least one terminal carbonyl, and wherein components (A) and (B) are present in an amount such that the molar ratio of silicon-bonded hydrogen atoms contained in components (B) to silicon-bonded alkenyl groups contained in component (A) ranges from 0.1 to 20, and preferably ranges from 0.25 to 5.0, and most preferably from 0.25 to 2.0, and (G) at least one cure rate controller G. <EOS>