mhurhangee/patent-ind-claim-en huggingface dataset:
A method for determining the sequence of a nucleic acid comprising: - providing at least one nucleic acid bound to a support; - contacting the nucleic acid with an enzyme in the presence of (i) at least two primers able to hybridise to the same strand of said at least one nucleic acid at different positions and (ii) four labelled moieties each comprising a different nucleotide analogue selected from dGTP, dCTP, dTTP, dUTP, and dATP, each of the four labelled moieties having a unique label which is different from the unique labels of the other three labelled moieties, under conditions permitting hybridisation; - hybridising the at least two primers to the same strand of the nucleic acid; - performing primer extensions on said same strand of the nucleic acid at each of the at least two primers to give a plurality of extension reads, each extension read extending from one of the at least two primers, wherein the same set of four labelled moieties are used for each extension read; - obtaining signal data corresponding to at least one nucleotide base incorporated at each of the primer extensions; and - determining from said signal data the identity of the nucleotide bases and allocating said bases to an extension read; wherein the at least two primers comprise blocked and unblocked primers to chemically differentiate between each extension read; wherein the at least two primers comprise differing levels of blocked and unblocked primers such that plurality of extension reads are chemically differentiated by making one of the reads brighter than the other. - providing at least one nucleic acid bound to a support; - contacting the nucleic acid with an enzyme in the presence of (i) at least two primers able to hybridise to the same strand of said at least one nucleic acid at different positions and (ii) four labelled moieties each comprising a different nucleotide analogue selected from dGTP, dCTP, dTTP, dUTP, and dATP, each of the four labelled moieties having a unique label which is different from the unique labels of the other three labelled moieties, under conditions permitting hybridisation; - hybridising the at least two primers to the same strand of the nucleic acid; - performing primer extensions on said same strand of the nucleic acid at each of the at least two primers to give a plurality of extension reads, each extension read extending from one of the at least two primers, wherein the same set of four labelled moieties are used for each extension read; - obtaining signal data corresponding to at least one nucleotide base incorporated at each of the primer extensions; and - determining from said signal data the identity of the nucleotide bases and allocating said bases to an extension read;
A method for preparing a hydrophobic silica aerogel, the method comprising Soxhlet extracting a hydrophobic silica wet gel, wherein the hydrophobic silica wet gel is a hydrophobic silica lyogel or a hydrophobic silica hydrogel, solvent substitution, washing, and drying are simultaneously performed on the hydrophobic silica wet gel during the Soxhlet extraction, and the Soxhlet extraction is performed in a pressure of 40 bar to 70 bar by using carbon dioxide as an extraction solvent, or in a pressure of 5 bar to 20 bar by using dimethyl ether as an extraction solvent.
An isolated monoclonal antibody that specifically binds to a human Siglec-7 polypeptide and to a human Siglec-9 polypeptide, wherein the antibody causes an increase in CD137 expression in Siglec-expressing NK cells when the NK cells are brought into contact with a target human cell bearing a ligand of the Siglec on the target cell surface.
Nozzle for a vacuum cleaner , the nozzle comprising: - a rotatable member for picking up particles from a surface to be cleaned, the rotatable member being arranged around a longitudinal axis , and - a cleaning arrangement for removing articles entangled to the rotatable member , the nozzle being characterized in that it further comprises: - a nozzle cover that at least partly is made of transparent material such that the rotatable member may be visible through the nozzle cover . - a rotatable member for picking up particles from a surface to be cleaned, the rotatable member being arranged around a longitudinal axis , and - a cleaning arrangement for removing articles entangled to the rotatable member , the nozzle being characterized in that it further comprises: - a nozzle cover that at least partly is made of transparent material such that the rotatable member may be visible through the nozzle cover .
A dispensing unit, comprising: a housing comprising a first end and a second end; and a plurality of storage assemblies, wherein the plurality of storage assemblies are arranged in parallel with one another within the housing, each storage assembly comprising: a plurality of compartments arranged linearly along an axis of the housing, each of the compartments being configured to store an item; a cover coupled with the housing and extending between the first end and the second end such that the cover is positioned over the plurality of compartments; and an actuator coupled with the cover, the actuator being configured to retract the cover to draw a distal end of the cover from the first end toward the second end to expose a selected number of the plurality of compartments, and an optical sensor coupled with a leading edge of the cover, the optical sensor being configured to determine whether one or more of the plurality of compartments are empty as the cover is moved along a length of the housing. a housing comprising a first end and a second end; and a plurality of storage assemblies, wherein the plurality of storage assemblies are arranged in parallel with one another within the housing, each storage assembly comprising: a plurality of compartments arranged linearly along an axis of the housing, each of the compartments being configured to store an item; a cover coupled with the housing and extending between the first end and the second end such that the cover is positioned over the plurality of compartments; and an actuator coupled with the cover, the actuator being configured to retract the cover to draw a distal end of the cover from the first end toward the second end to expose a selected number of the plurality of compartments, and an optical sensor coupled with a leading edge of the cover, the optical sensor being configured to determine whether one or more of the plurality of compartments are empty as the cover is moved along a length of the housing. a plurality of compartments arranged linearly along an axis of the housing, each of the compartments being configured to store an item; a cover coupled with the housing and extending between the first end and the second end such that the cover is positioned over the plurality of compartments; and an actuator coupled with the cover, the actuator being configured to retract the cover to draw a distal end of the cover from the first end toward the second end to expose a selected number of the plurality of compartments, and an optical sensor coupled with a leading edge of the cover, the optical sensor being configured to determine whether one or more of the plurality of compartments are empty as the cover is moved along a length of the housing.
Intake pipe for an internal combustion engine for the detachable connection with a fuel distributor rail , comprising a flange , which houses a valve section of a fuel injection valve , wherein the flange has an upper area facing the fuel injection valve , and a lower area facing the intake pipe , characterised in that in the upper area of the flange there is an element with a section that forms due to a provided material weakness in section a predetermined breaking point that has at least partially reduced strength compared with its respective adjacent areas.
A method for capturing charging current curves (16a-c) for electric vehicles (8a-c) at charging stations (2a-c) comprising: - capturing of a charging current curve at a charging station (2a-c), - storing of the charging current curve together with a vehicle identification of the charging vehicle (8a-c), characterized in that - for each vehicle identification a charging current curve (16a-c) at a plurality of charging stations (2a-c) is stored, - a charging current curve characterizing the vehicle (8a-c) is calculated for each respective vehicle (8a-c) identification from the stored charging current curves at different charging stations (2a-c), wherein - the charging current curve characterizing the vehicle (8a-c) is calculated as an average value of the stored charging current curves (16a-c) for the vehicle identification, and - for the respective vehicle identification, a present charging current curve is compared with charging current curve characterizing the vehicle (8a-c) and in case of a derivation of the present charging current curve from the charging current curve characterizing the vehicle (8a-c) which is greater than a threshold, a signal is output. - capturing of a charging current curve at a charging station (2a-c), - storing of the charging current curve together with a vehicle identification of the charging vehicle (8a-c), characterized in that - for each vehicle identification a charging current curve (16a-c) at a plurality of charging stations (2a-c) is stored, - a charging current curve characterizing the vehicle (8a-c) is calculated for each respective vehicle (8a-c) identification from the stored charging current curves at different charging stations (2a-c), wherein - the charging current curve characterizing the vehicle (8a-c) is calculated as an average value of the stored charging current curves (16a-c) for the vehicle identification, and - for the respective vehicle identification, a present charging current curve is compared with charging current curve characterizing the vehicle (8a-c) and in case of a derivation of the present charging current curve from the charging current curve characterizing the vehicle (8a-c) which is greater than a threshold, a signal is output.
A tube for making a roller, comprising: a cylindrical tube body , wherein in the tube body , a plurality of tube body support members are arranged at intervals along the length direction of the tube body ; wherein the tube body support member comprises a body ; wherein an outer edge of the body is connected to a connecting portion , and the other end of the connecting portion is connected to a support portion ; wherein the angle between the support portion and a horizontal plane is an acute angle, and the diameter of the circle formed by the outer edge of the support portion is greater than the diameter of the circle formed by the outer edge of the connecting portion ; a first support shaft ; wherein the body is provided with a shaft hole matching the first support shaft ; wherein the first support shaft passes through the shaft holes of at least two bodies ; characterized by further comprising, a second support shaft ; wherein the first support shaft is of a hollow structure, and a plurality of the tube body support members are arranged in the first support shaft ; wherein the tube body support members arranged in the first support shaft are provided with shaft holes matching the second support shaft , and the second support shaft passes through the shaft holes of at least two tube body support members . a cylindrical tube body , wherein in the tube body , a plurality of tube body support members are arranged at intervals along the length direction of the tube body ; wherein the tube body support member comprises a body ; wherein an outer edge of the body is connected to a connecting portion , and the other end of the connecting portion is connected to a support portion ; wherein the angle between the support portion and a horizontal plane is an acute angle, and the diameter of the circle formed by the outer edge of the support portion is greater than the diameter of the circle formed by the outer edge of the connecting portion ; wherein the tube body support member comprises a body ; wherein an outer edge of the body is connected to a connecting portion , and the other end of the connecting portion is connected to a support portion ; wherein the angle between the support portion and a horizontal plane is an acute angle, and the diameter of the circle formed by the outer edge of the support portion is greater than the diameter of the circle formed by the outer edge of the connecting portion ; a first support shaft ; wherein the body is provided with a shaft hole matching the first support shaft ; wherein the first support shaft passes through the shaft holes of at least two bodies ; characterized by further comprising, a second support shaft ; wherein the first support shaft is of a hollow structure, and a plurality of the tube body support members are arranged in the first support shaft ; wherein the tube body support members arranged in the first support shaft are provided with shaft holes matching the second support shaft , and the second support shaft passes through the shaft holes of at least two tube body support members .
A machine with a tamping unit having a plurality of tamping unit segments arranged one behind the other with respect to a longitudinal direction of the machine for the simultaneous tamping of a plurality of sleepers of a track positioned directly one behind the other, wherein each tamping unit segment comprises a height-adjustable tamping tool carrier on which opposing tamping tools are mounted, which are coupled to a vibration drive arranged on the tamping tool carrier via squeezing cylinders , characterised in that the respective vibration drive comprises an eccentric shaft with a first eccentric disc and a second eccentric disc , whose axes of symmetry , together with a common axis of rotation span two eccentric planes which enclose a relative angle (δ) to one another, that a first of the squeezing cylinders is mounted on the first eccentric disc , an opposing second of the squeezing cylinders is mounted on the second eccentric disc , and that the cylinder axis of the first squeezing cylinder and that the cylinder axis of the opposing second squeezing cylinder enclose a position angle (β) which is approximated to the relative angle (δ) of the eccentric planes .
A device comprising a tactile screen , more especially for a display for visually impaired people, characterised in that said tactile sceen comprises imprints comprising exactly ten imprints located at positions corresponding to the ten spread fingers of a user's right and left hands to be able to write in Braille, each of the ten imprints having a recessed mark substantially corresponding to the tip of a user's finger, the ten imprints being configured to guide the positioning of the user's fingers.
Two-roller roll press having a machine frame with two rollers, which have shaft journals at their respective axial ends for mounting in a bearing construction, which said shaft journals are fastened in the machine frame, wherein at least one of the rollers is mounted at one or both shaft journals in a thrust bearing construction characterized in that , the thrust bearing construction comprises a thrust bearing , a thrust bearing housing ring , an outer thrust bearing cap and a bearing cap , the thrust bearing is shrunk onto a shaft journal , thrust bearing is surrounded by the ring-shaped thrust bearing housing in the circumferential direction, wherein the trust bearing housing ring can be removed while the trust bearing is still mounted, wherein the trust bearing is free accessible for heat shrinking or removing onto shaft journal with the ring-shaped thrust bearing housing removed and the outer thrust bearing cap removed, which makes it possible to heat shrink the thrust bearing during mounting, wherein thrust bearing housing ring and the bearing cap are detachably connected into one unit, which is detachably fastened to the outer thrust bearing cap , which is in turn detachably fastened to the bearing housing.
A microcracked ceramic body, comprising: a predominant phase of zirconium tin titanate a microcrack density Nb 3 , wherein Nb 3 ≥ k 1 [0.102 + ×6.00x10 4 (CTE m in) + 1.23×10 10 (CTE min ) 2 + 8.38×10 14 (CTE min ) 3 ] and wherein k 1 is at least 1, wherein CTE min is a minimum lattice axial coefficient of thermal expansion (CTE) from 25 to 1000°C of the zirconium tin titanate phase, and CTE min is in units of °C -1 ; and a dilatometric coefficient of thermal expansion (CTE) from 25 to 1000°C of not more than 4×10 -7 °C -1 as measured by dilatometry, wherein the microcrack density Nb 3 is at least one of (Nb 3 )lA and (Nb 3 )EM, and wherein (Nb 3 )lA is the microcrack density Nb 3 determined by image analysis and (Nb 3 )EM is the microcrack density Nb 3 determined by Young's modulus. a predominant phase of zirconium tin titanate a microcrack density Nb 3 , wherein Nb 3 ≥ k 1 [0.102 + ×6.00x10 4 (CTE m in) + 1.23×10 10 (CTE min ) 2 + 8.38×10 14 (CTE min ) 3 ] and wherein k 1 is at least 1, wherein CTE min is a minimum lattice axial coefficient of thermal expansion (CTE) from 25 to 1000°C of the zirconium tin titanate phase, and CTE min is in units of °C -1 ; and a dilatometric coefficient of thermal expansion (CTE) from 25 to 1000°C of not more than 4×10 -7 °C -1 as measured by dilatometry, wherein the microcrack density Nb 3 is at least one of (Nb 3 )lA and (Nb 3 )EM, and wherein (Nb 3 )lA is the microcrack density Nb 3 determined by image analysis and (Nb 3 )EM is the microcrack density Nb 3 determined by Young's modulus.
A pixel unit cell comprising: four photodiode regions comprising an infrared light, IR, photodiode region (Z) and three visible light photodiode regions (R, G, B) arranged in a 2x2 matrix; an IR capacitance region (C2) associated with the IR photodiode region (Z); an IR transfer gate (Q2 Z) coupled between the IR photodiode region (Z) and the IR capacitance region (C2); a single visible light capacitance region (C1) associated with the three visible light photodiode regions (R, G, B); and for each of the three visible light photodiode regions (R, G, B), a respective visible light transistor gate (Q2 R, Q2 G, Q2 B) coupled between the visible light photodiode region and the single visible light capacitive region, wherein the single visible light capacitance region (C1) is positioned at a shared corner of the three visible light photodiode regions (R, G, B), and the IR capacitance region (C2) is positioned at a corner of the IR photodiode region (Z) that is not the shared corner of the three visible light photodiode regions. four photodiode regions comprising an infrared light, IR, photodiode region (Z) and three visible light photodiode regions (R, G, B) arranged in a 2x2 matrix; an IR capacitance region (C2) associated with the IR photodiode region (Z); an IR transfer gate (Q2 Z) coupled between the IR photodiode region (Z) and the IR capacitance region (C2); a single visible light capacitance region (C1) associated with the three visible light photodiode regions (R, G, B); and for each of the three visible light photodiode regions (R, G, B), a respective visible light transistor gate (Q2 R, Q2 G, Q2 B) coupled between the visible light photodiode region and the single visible light capacitive region, wherein the single visible light capacitance region (C1) is positioned at a shared corner of the three visible light photodiode regions (R, G, B), and the IR capacitance region (C2) is positioned at a corner of the IR photodiode region (Z) that is not the shared corner of the three visible light photodiode regions.
An apparatus, comprising: a probe , configured for insertion into a body cavity of a patient and comprising a location sensor for measuring a position of a distal end of the probe inside the body cavity; and a processor configured: to capture, from an imaging system, a three-dimensional image of the body cavity, to construct, using the captured 3D image, a simulated surface of the body cavity, to map, while inserting the probe into the body cavity, multiple positions within respective regions of the body cavity, in response to multiple location measurements received from the location sensor , so as to generate respective mapped regions of the simulated surface, and characterized by the processor being further configured: to configure the simulated surface of the body cavity to indicate one or more unmapped regions of the simulated surface by subtracting the respective mapped regions from the simulated surface. a probe , configured for insertion into a body cavity of a patient and comprising a location sensor for measuring a position of a distal end of the probe inside the body cavity; and a processor configured: to capture, from an imaging system, a three-dimensional image of the body cavity, to construct, using the captured 3D image, a simulated surface of the body cavity, to map, while inserting the probe into the body cavity, multiple positions within respective regions of the body cavity, in response to multiple location measurements received from the location sensor , so as to generate respective mapped regions of the simulated surface, and characterized by the processor being further configured: to configure the simulated surface of the body cavity to indicate one or more unmapped regions of the simulated surface by subtracting the respective mapped regions from the simulated surface. to capture, from an imaging system, a three-dimensional image of the body cavity, to construct, using the captured 3D image, a simulated surface of the body cavity, to map, while inserting the probe into the body cavity, multiple positions within respective regions of the body cavity, in response to multiple location measurements received from the location sensor , so as to generate respective mapped regions of the simulated surface, and characterized by the processor being further configured: to configure the simulated surface of the body cavity to indicate one or more unmapped regions of the simulated surface by subtracting the respective mapped regions from the simulated surface.
Electrical contact apparatus for an electrical machine with - a brush facility , which comprises a brush , - a shaft , which is mounted such that it can rotate in relation to the brush facility , and - a slip ring facility , which is arranged on the shaft in a rotationally fixed manner, wherein - the slip ring facility comprises a slip ring , which is in electrical contact with the brush of the brush facility , wherein - the slip ring facility has a carrier element for holding the slip ring and the carrier element has a plurality of second cooling channels for guiding the coolant, which extend substantially in the radial direction of the shaft , characterised in that - the electrical contact apparatus has a recess for guiding a coolant between the shaft and the slip ring facility , - the recess completely surrounds the shaft along its circumferential direction and wherein arranged between the shaft and the slip ring facility is at least one first cooling channel , which extends along an axial direction of the shaft from an end face of the slip ring facility to the recess . - a brush facility , which comprises a brush , - a shaft , which is mounted such that it can rotate in relation to the brush facility , and - a slip ring facility , which is arranged on the shaft in a rotationally fixed manner, wherein - the slip ring facility comprises a slip ring , which is in electrical contact with the brush of the brush facility , wherein - the slip ring facility has a carrier element for holding the slip ring and the carrier element has a plurality of second cooling channels for guiding the coolant, which extend substantially in the radial direction of the shaft , characterised in that - the electrical contact apparatus has a recess for guiding a coolant between the shaft and the slip ring facility , - the recess completely surrounds the shaft along its circumferential direction and