A compound represented by Formula 2, stereoisomers thereof or pharmaceutically acceptable salts thereof: in Formula 2, R 1 is H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 hydroxyalkyl, C 1-6 cyanoalkyl, C 1-6 haloalkyl, hydroxy, cyano, halogen, C(=O)-OH, C(=O)-O-C 1-6 alkyl, S(=O) 2 -C 1-6 alkyl, aryl or heteroaryl; X is C-A 1 or N, Y is C-A 2 or N-A 4 , Z is C-A 3 or N-A 5 wherein at least one of X, Y and Z includes N; at least one of a bond between X and Y or a bond between Y and Z is a double bond, and if the bond between X and Y is the double bond, A 1 or A 4 is null; A 1 to As are each independently H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 hydroxyalkyl, C 1-6 haloalkyl, C 1-6 cyanoalkyl, C(=O)-OH, C(=O)-O-C 1-6 alkyl, S(=O) 2 -C 1-6 alkyl, -C(=O)-NH-C 1-6 haloalkyl, aryl or heteroaryl; R 2 is H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 hydroxyalkyl, C 1-6 cyanoalkyl, C 1-6 haloalkyl, hydroxy, cyano, halogen, C(=O)-OH, C(=O)-O-C 1-6 alkyl, S(=O) 2 -C 1-6 alkyl, aryl or heteroaryl; n and m are each independently 0 or 1; D 2 is -C(=O)-; D 3 is -NR 3 -, or a single bond; D 4 is H, C 1-6 alkyl, C 1-6 alkenyl, C 1-6 cyanoalkyl, C 3-7 cycloalkyl, 5-6-membered heterocycloalkyl, aryl or heteroaryl; wherein at least one H of C 1-6 alkyl, C 1-6 alkenyl or C 1-6 cyanoalkyl may be substituted with C 3-7 cycloalkyl, aryl, heteroaryl or cyano, at least one H of C 3-7 cycloalkyl or 5-6-membered heterocycloalkyl may be substituted with C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 cyanoalkyl, cyano or halogen, and at least one H of aryl or heteroaryl may be substituted with C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl, C 1-6 cyanoalkyl, C 1-6 thioalkyl, hydroxy, cyano, nitro or halogen; and R 3 and R 4 are each independently H, C 1-6 alkyl or C 1-6 haloalkyl; or wherein the compound is N-(4-(7-(2-(4-methylpiperazin-1-yl)propanamido)-1H-indol-3-yl)pyridin-2-yl)cyclopropanecarboxamide. R 1 is H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 hydroxyalkyl, C 1-6 cyanoalkyl, C 1-6 haloalkyl, hydroxy, cyano, halogen, C(=O)-OH, C(=O)-O-C 1-6 alkyl, S(=O) 2 -C 1-6 alkyl, aryl or heteroaryl; X is C-A 1 or N, Y is C-A 2 or N-A 4 , Z is C-A 3 or N-A 5 wherein at least one of X, Y and Z includes N; at least one of a bond between X and Y or a bond between Y and Z is a double bond, and if the bond between X and Y is the double bond, A 1 or A 4 is null; A 1 to As are each independently H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 hydroxyalkyl, C 1-6 haloalkyl, C 1-6 cyanoalkyl, C(=O)-OH, C(=O)-O-C 1-6 alkyl, S(=O) 2 -C 1-6 alkyl, -C(=O)-NH-C 1-6 haloalkyl, aryl or heteroaryl; R 2 is H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 hydroxyalkyl, C 1-6 cyanoalkyl, C 1-6 haloalkyl, hydroxy, cyano, halogen, C(=O)-OH, C(=O)-O-C 1-6 alkyl, S(=O) 2 -C 1-6 alkyl, aryl or heteroaryl; n and m are each independently 0 or 1; D 2 is -C(=O)-; D 3 is -NR 3 -, or a single bond; D 4 is H, C 1-6 alkyl, C 1-6 alkenyl, C 1-6 cyanoalkyl, C 3-7 cycloalkyl, 5-6-membered heterocycloalkyl, aryl or heteroaryl; wherein at least one H of C 1-6 alkyl, C 1-6 alkenyl or C 1-6 cyanoalkyl may be substituted with C 3-7 cycloalkyl, aryl, heteroaryl or cyano, at least one H of C 3-7 cycloalkyl or 5-6-membered heterocycloalkyl may be substituted with C 1-6 alkyl, C 1-6 haloalkyl, C 1-6 cyanoalkyl, cyano or halogen, and at least one H of aryl or heteroaryl may be substituted with C 1-6 alkyl, C 1-6 alkoxy, C 1-6 haloalkyl, C 1-6 hydroxyalkyl, C 1-6 cyanoalkyl, C 1-6 thioalkyl, hydroxy, cyano, nitro or halogen; and R 3 and R 4 are each independently H, C 1-6 alkyl or C 1-6 haloalkyl; or wherein the compound is N-(4-(7-(2-(4-methylpiperazin-1-yl)propanamido)-1H-indol-3-yl)pyridin-2-yl)cyclopropanecarboxamide. <EOS>