mhurhangee/patent-ind-claim-en huggingface dataset:
A DUX4-fl antisense nucleic acid molecule or DUX4-fl RNAi molecule agent capable of inhibiting or suppressing the level of DUX4-fl expression, for use in a method of treating a human subject suffering from, or at risk for developing Facioscapulohumeral Dystrophy (FSHD), wherein the human subject has a functional polyadenylation signal sequence operationally linked to exon 3 of the DUX4 gene, wherein the DUX4 gene is located in a portion of the genomic DNA of the subject corresponding to the distal D4Z4-pLAM region on chromosome 4.
An ultrasonic imaging apparatus comprising: an ultrasonic probe configured to transmit an ultrasonic signal to an object (ob) and receive an echo signal reflected from the object (ob); a display configured to output an ultrasound image (A) output by the ultrasonic probe and a medical image (B) having a modality different from that of the ultrasound image (A) in a matched state; an inputter configured to receive a user input for adjusting a range of an output area of the medical image (B); and a controller configured to control an ultrasonic beam of the ultrasonic probe to adjust an output area of the ultrasound image (A) in response to detecting that the output area of the medical image (B) is adjusted by the user input; characterized in that the ultrasonic imaging apparatus is configured to output the ultrasound image (A) in real time in a state matched with the adjusted medical image (B) by controlling only the ultrasonic beam while the ultrasonic probe is fixed to the object (ob). an ultrasonic probe configured to transmit an ultrasonic signal to an object (ob) and receive an echo signal reflected from the object (ob); a display configured to output an ultrasound image (A) output by the ultrasonic probe and a medical image (B) having a modality different from that of the ultrasound image (A) in a matched state; an inputter configured to receive a user input for adjusting a range of an output area of the medical image (B); and a controller configured to control an ultrasonic beam of the ultrasonic probe to adjust an output area of the ultrasound image (A) in response to detecting that the output area of the medical image (B) is adjusted by the user input; characterized in that the ultrasonic imaging apparatus is configured to output the ultrasound image (A) in real time in a state matched with the adjusted medical image (B) by controlling only the ultrasonic beam while the ultrasonic probe is fixed to the object (ob).
A clamp for retaining an over-molded plastic component to a substrate , the clamp comprising: a generally annular band having an inner surface defining an inner cavity for receiving the substrate that is rotatable about a central axis and an opposing outer surface for receiving an over molded plastic component , and characterized in that , said band comprises a first end (46; 46'; 62) and a second end (48; 48'; 64), the second end is engageable with the first end to form a coupling portion ; and a plurality of retaining features formed in the generally annular band ; wherein the plurality of retaining features extend axially, and each of the plurality of retaining features (36; 50) defines a trough in the inner surface and a crest in the outer surface ; wherein at least one of the plurality of retaining features is defined by the coupling portion ; and wherein each trough defines a gap (D) extending axially the full width (W1) of the generally annular band such that each trough forms an elongated channel. a generally annular band having an inner surface defining an inner cavity for receiving the substrate that is rotatable about a central axis and an opposing outer surface for receiving an over molded plastic component , and characterized in that , said band comprises a first end (46; 46'; 62) and a second end (48; 48'; 64), the second end is engageable with the first end to form a coupling portion ; and a plurality of retaining features formed in the generally annular band ; wherein the plurality of retaining features extend axially, and each of the plurality of retaining features (36; 50) defines a trough in the inner surface and a crest in the outer surface ; wherein at least one of the plurality of retaining features is defined by the coupling portion ; and wherein each trough defines a gap (D) extending axially the full width (W1) of the generally annular band such that each trough forms an elongated channel.
Contact-adhesive product comprising a substrate and a polyurethaneurea obtainable by reacting at least A) an aliphatic polyisocyanate component having an average isocyanate functionality of ≥ 1.8 and ≤ 2.6, B) a polymeric polyetherpolyol component which contains or consists of a mixture of poly(tetramethylene glycol) polyetherpolyols, where the poly(tetramethylene glycol) polyetherpolyols differ in their number-average molecular weights, C) an amino-functional chain extender component having at least 2 isocyanate-reactive amino groups, containing at least one amino-functional compound C1) that has no ionic or ionogenic groups and an amino-functional compound C2) that has ionic or ionogenic groups, D) optionally further hydrophilizing components other than C2), E) optionally hydroxy-functional compounds having a molecular weight of 62 to 399 mol/g, F) optionally at least one further polymeric polyol other than B), G) a compound having exactly one isocyanate-reactive group or a compound having more than one isocyanate-reactive group, where only one of the isocyanate-reactive groups reacts with the isocyanate groups present in the reaction mixture under the reaction conditions chosen, and H) an aliphatic polyisocyanate component having an average isocyanate functionality of > 2.6 and ≤ 4, where the molar ratio of component G) to component H) is 5:1 to 1:5 and where components B) and F) together contain ≤ 30% by weight of component F), based on the total mass of components B) and F). A) an aliphatic polyisocyanate component having an average isocyanate functionality of ≥ 1.8 and ≤ 2.6, B) a polymeric polyetherpolyol component which contains or consists of a mixture of poly(tetramethylene glycol) polyetherpolyols, where the poly(tetramethylene glycol) polyetherpolyols differ in their number-average molecular weights, C) an amino-functional chain extender component having at least 2 isocyanate-reactive amino groups, containing at least one amino-functional compound C1) that has no ionic or ionogenic groups and an amino-functional compound C2) that has ionic or ionogenic groups, D) optionally further hydrophilizing components other than C2), E) optionally hydroxy-functional compounds having a molecular weight of 62 to 399 mol/g, F) optionally at least one further polymeric polyol other than B), G) a compound having exactly one isocyanate-reactive group or a compound having more than one isocyanate-reactive group, where only one of the isocyanate-reactive groups reacts with the isocyanate groups present in the reaction mixture under the reaction conditions chosen, and H) an aliphatic polyisocyanate component having an average isocyanate functionality of > 2.6 and ≤ 4, where the molar ratio of component G) to component H) is 5:1 to 1:5 and where components B) and F) together contain ≤ 30% by weight of component F), based on the total mass of components B) and F).
Multi-step planetary transmission for a wind power plant, comprising an input-side first planetary stage which is accommodated in a common transmission housing and downstream of which at least one second planetary stage is connected via a spline system of a sun gear shaft of the first planetary stage , the following being provided, starting from an oil feed duct which is configured in a stationary manner in the transmission housing : - a first oil-conveying duct which is loaded via the said oil feed duct for supplying the planetary gear bearings of the first planetary stage with oil, - a second oil-conveying duct which is loaded via the said oil feed duct for supplying the planetary gear bearings of the second planetary stage with oil, and - a third oil-conveying duct which is loaded via the said oil feed duct for supplying the spline system with oil; characterized in that , in order to supply the spline system with oil, the third oil-conveying duct branches off in the radial direction from the second oil-conveying duct which runs at least partially through the planetary carrier of the second planetary stage in the axial direction and is longer than the latter, in order to open out in the region of the spline system . - a first oil-conveying duct which is loaded via the said oil feed duct for supplying the planetary gear bearings of the first planetary stage with oil, - a second oil-conveying duct which is loaded via the said oil feed duct for supplying the planetary gear bearings of the second planetary stage with oil, and - a third oil-conveying duct which is loaded via the said oil feed duct for supplying the spline system with oil;
Vacuum drum for a labelling unit of a labelling machine, in particular for labelling containers or the like, comprising a plurality of segments which are rotatable in a direction of rotation (B) about a drum axis (TA) of the vacuum drum , and which each have at least one pair of vacuum holders which are arranged on a corresponding carrier plate and which comprise vacuum holders (9.1, 9.2) which are provided offset in relation to one another at a circumferential surface of the vacuum drum about the drum axis (TA) in the direction of rotation (B), each with a vacuum holder housing (36.1, 36.2), wherein a front vacuum holder (9.1), in relation to the direction of rotation (B), is provided in order to hold in each case a front label end (3.1) of a corresponding label , and a rear vacuum holder (9.2), in relation to the direction of rotation (B), is provided for holding an associated rear label end (3.2) at the circumferential surface of the vacuum drum , and wherein the circumferential surface of the corresponding segment of the vacuum drum is formed between the respective front and rear vacuum holders (9.1, 9.2) by means of a circular-arc shaped segment surface portion , characterised in that at least the carrier plate and/or the respective vacuum holder housing (36.1, 36.2) of the vacuum holder pair and/or the segment surface portion extending between the front and rear vacuum holders (9.1, 9.2) of this pair of vacuum holders of at least one segment is/are produced by means of an additive manufacturing method, and that at least one vacuum holder housing (9.1, 9.2) of the pair of vacuum holders is arranged on the carrier plate by means of at least one vacuum line (21.1, 21.2), wherein the at least one vacuum line (21.1, 21.2) is produced by means of an additive manufacturing process.
Natural composition with UV radiation absorption capacity, comprising a colloidal hydroalcoholic concentrate extract of Amphipteryngium adstringens bark and leaves and between 12 and 36% w/w of tannins measured as tannic acid concentration, for use in the prevention and treatment of induced skin lesions due to an overexposure to sun radiation.
Energy storage device for storage of electrical energy comprising at least one storage element, wherein at least one storage element comprises at least one electroplax or at least one electroplax fibre, characterized in that the energy storage device has at least one container , that an electrically non-conducting fluid is accommodated in the container , that the electroplax and/or the electroplax fibres are arranged in the container at least in sections, that the electroplax and/or the electroplax fibres are surrounded by a fluid at least in sections, in particular completely, that the fluid has preserving properties, that the fluid consists at least partially of an alcohol, in particular of ethanol, that the electroplax or the electroplax fibres are produced artificially by cultivation from cell cultures, that the container is manufactured from a non-electrically conductive material and that the container has at least two contact regions on its outer wall wherein each contact region is connected in an electrically conductive manner to one of the electric poles of at least one electroplax and/or an electroplax fibre. characterized in that the energy storage device has at least one container , that an electrically non-conducting fluid is accommodated in the container , that the electroplax and/or the electroplax fibres are arranged in the container at least in sections, that the electroplax and/or the electroplax fibres are surrounded by a fluid at least in sections, in particular completely, that the fluid has preserving properties, that the fluid consists at least partially of an alcohol, in particular of ethanol, that the electroplax or the electroplax fibres are produced artificially by cultivation from cell cultures, that the container is manufactured from a non-electrically conductive material and that the container has at least two contact regions on its outer wall wherein each contact region is connected in an electrically conductive manner to one of the electric poles of at least one electroplax and/or an electroplax fibre.
A method for detecting a presence of an RF signal, comprising: receive (S304) a series of data samples of an RF frequency channel output from a radio receiver; forming (S306) with at least one computer processor a sample correlation matrix A from said series of data samples of said radio frequency channel; calibrating the sample correlation matrix A by removing correlation effects introduced by radio receiver signal processing by multiplying the sample correlation matrix A by an inverted sample correlation matrix which is created based on a source of white noise; calculating (S308) with said at least one computer processor a trace tr( A ) of the calibrated sample correlation matrix; calculating (S310) with said at least one computer processor a determinant det( A ) of the calibrated sample correlation matrix; computing (S312) with said at least one computer processor S = T · det( A ) - (tr( A ) / N) N where N is the number of rows and the number of columns of the sample correlation matrix A and T is a threshold value; selectively determining (S314) a presence or absence of a signal on said radio frequency channel based on a calculated value of S; and selecting said value of T so that negative values of S are minimal when said series of data samples is comprised exclusively of white noise. receive (S304) a series of data samples of an RF frequency channel output from a radio receiver; forming (S306) with at least one computer processor a sample correlation matrix A from said series of data samples of said radio frequency channel; calibrating the sample correlation matrix A by removing correlation effects introduced by radio receiver signal processing by multiplying the sample correlation matrix A by an inverted sample correlation matrix which is created based on a source of white noise; calculating (S308) with said at least one computer processor a trace tr( A ) of the calibrated sample correlation matrix; calculating (S310) with said at least one computer processor a determinant det( A ) of the calibrated sample correlation matrix; computing (S312) with said at least one computer processor S = T · det( A ) - (tr( A ) / N) N where N is the number of rows and the number of columns of the sample correlation matrix A and T is a threshold value; selectively determining (S314) a presence or absence of a signal on said radio frequency channel based on a calculated value of S; and selecting said value of T so that negative values of S are minimal when said series of data samples is comprised exclusively of white noise.
Apparatus for preparing foam for incorporation into cementitious slurry, comprising a conduit having an inlet for receiving a gas feed and a surfactant feed , and an outlet for allowing the exit of foam, the conduit housing a porous plug that provides a partial barrier to fluid flow along the conduit, the plug comprising a plurality of particles that are packed in a regular array, the particles defining a three-dimensional network of pores extending therebetween, wherein the apparatus comprises a resilient component located between the plug and the conduit, wherein the resilient component comprises a sleeve disposed on a radially inward side of the conduit.
An alkaline water electrolysis method for electrolyzing an alkaline electrolytic solution using an alkaline water electrolyzer having an anode chamber housing an anode, a cathode chamber housing a cathode, and a diaphragm separating the anode chamber from the cathode chamber, the method comprising: an electrolysis step of performing alkaline water electrolysis in the alkaline water electrolyzer, including storing the electrolytic solution in a circulation tank, feeding the electrolytic solution stored in the circulation tank to the anode chamber and to the cathode chamber, returning a cathode-side electrolytic solution generated in the cathode chamber and an anode-side electrolytic solution generated in the anode chamber to the circulation tank, mixing together the cathode-side electrolytic solution and the anode-side electrolytic solution in the circulation tank, and circulating the mixed electrolytic solution between the cathode chamber and the circulation tank and between the anode chamber and the circulation tank; and a step of adding a catalyst activation material formed of a metal salt soluble in the electrolytic solution prior to starting of the electrolysis step, wherein in the electrolysis step, a metal component in the catalyst activation material is deposited on a surface of the cathode. an electrolysis step of performing alkaline water electrolysis in the alkaline water electrolyzer, including storing the electrolytic solution in a circulation tank, feeding the electrolytic solution stored in the circulation tank to the anode chamber and to the cathode chamber, returning a cathode-side electrolytic solution generated in the cathode chamber and an anode-side electrolytic solution generated in the anode chamber to the circulation tank, mixing together the cathode-side electrolytic solution and the anode-side electrolytic solution in the circulation tank, and circulating the mixed electrolytic solution between the cathode chamber and the circulation tank and between the anode chamber and the circulation tank; and a step of adding a catalyst activation material formed of a metal salt soluble in the electrolytic solution prior to starting of the electrolysis step, wherein in the electrolysis step, a metal component in the catalyst activation material is deposited on a surface of the cathode.
Profile rod for a sales counter , having an essentially rectangular, in particular square, cross section, having at least a first corner guidance and fastening groove and having at least a second corner guidance and fastening groove , wherein the corner guidance and fastening grooves are arranged axially, lengthwise, on two opposite corners and two abutting sides , wherein the two corner guidance and fastening grooves have an essentially L-shaped cross section, and in that the two sides in which there are no corner guidance and fastening grooves enclose a corner , in which an outer-corner profile is formed, wherein, in one side in which a corner guidance and fastening groove is arranged, a longitudinal-guidance and fastening groove is arranged, and wherein furthermore, in the other side in which a corner guidance and fastening groove is arranged, there is no longitudinal-guidance and fastening groove .
A cylinder lock with control key, including a stator , security pins, a rotor and a key , the rotor rotating in the stator under the action of the key , and, as additional means for authorizing the rotation of the rotor, an elastic leaf , the median plane of which contains the axis of the rotor, one end of which is attached in the rotor and the other end of which is free in radial movement, the free end of the elastic leaf being movable between an unstressed position, where it is completely housed in the rotor and where it allows the rotation of the rotor, and a stressed position, where it protrudes from the rotor and where it cooperates with a slot of the stator to prevent the rotation of the rotor, characterized in that the elastic leaf is made up of a first part parallel to the axis of the rotor and attached to the rotor , an intermediate part with a curved profile, extending toward the axis of the rotor , and an end part substantially perpendicular to the axis of the rotor and extending toward the outside of the rotor ; and in that the key includes, on its blade, an indentation whose profile encompasses that of the intermediate part and the end part of the elastic leaf , such that, after introduction of the key , the elastic leaf , housed in said indentation , is not subject to any stress.
A thermal exchange assembly comprising: a cold plate configured to be placed on a semiconductor device , the cold plate including a window section ; a heat pipe, HP, directly coupled to the cold plate , the HP including a window , the window being a recessed or depressed portion of the HP , wherein the window is disposed on the window section ; and. a wick structure disposed between the window and the window section , characterised in that the wick structure extends from inside the HP and out of the window , and attaches to the window section of the cold plate . a cold plate configured to be placed on a semiconductor device , the cold plate including a window section ; a heat pipe, HP, directly coupled to the cold plate , the HP including a window , the window being a recessed or depressed portion of the HP , wherein the window is disposed on the window section ; and. a wick structure disposed between the window and the window section , characterised in that the wick structure extends from inside the HP and out of the window , and attaches to the window section of the cold plate .
Bait box arrangement , comprising a bait box having a tubular housing that comprises on one side an entrance opening for rodents and that is closed on the other side by means of a lid , wherein a receiving device for poisonous bait is allocated to the lid , wherein the bait box is provided with a fastening device for fastening the bait box in a wastewater facility and it is possible by means of the fastening device to mount the bait box arrangement in the wastewater facility in such a manner that the one side is facing the fluid level of the wastewater that is guided in the wastewater facility and that the other side points, with the lid together with the receiving device , into the opposite direction, characterised in that the housing comprises at least two curved sections .
Laminate comprising a first layer and a second layer directly covering the first layer, the first layer being a layer of a silicone rubber composition comprising a micrometric silicone powder and a mixture of crosslinkable organopolysiloxanes, the second layer being a layer of a silicone rubber composition comprising a hydrophobic silica and a mixture of crosslinkable organopolysiloxanes, the first layer and the second layer being crosslinked.
: A partially lighted T-bar for a suspended ceiling, comprising in combination: an elongate spine extending between opposing ends; a rest shelf at a lower portion of said spine; a lighting module covering a portion of an underside of said rest shelf between an end wall at one end of the T-bar and a mid-wall at an end of the lighting module at a mid-point of the T-bar; a light housing covering said portion of the underside of said rest shelf; and a plain unlit surface on a remainder of said underside of said rest shelf. an elongate spine extending between opposing ends; a rest shelf at a lower portion of said spine; a lighting module covering a portion of an underside of said rest shelf between an end wall at one end of the T-bar and a mid-wall at an end of the lighting module at a mid-point of the T-bar; a light housing covering said portion of the underside of said rest shelf; and a plain unlit surface on a remainder of said underside of said rest shelf.