mhurhangee/patent-ind-claim-en huggingface dataset:
Siponimod of the formula (I), or a pharmaceutically acceptable salt thereof, for use in a method of treating a patient suffering from multiple sclerosis, said method comprising the steps of: (i) testing whether or not the patient has the poor metabolizer genotype selected from the CYP2C9*3*3 and CYP2C9*2*3 genotypes; and (ii) if the patient has been identified as not having the poor metaboliser genotype, administering siponimod, or a pharmaceutically acceptable salt thereof, to the patient at the standard therapeutic dose; or (iii) if the patient has been identified as having the poor metaboliser genotype, either (a) administering siponimod, or a pharmaceutically acceptable salt thereof, to the patient at a therapeutic dose below that of the standard therapeutic dose; or (b) not administering siponimod to the patient. (i) testing whether or not the patient has the poor metabolizer genotype selected from the CYP2C9*3*3 and CYP2C9*2*3 genotypes; and (ii) if the patient has been identified as not having the poor metaboliser genotype, administering siponimod, or a pharmaceutically acceptable salt thereof, to the patient at the standard therapeutic dose; or (iii) if the patient has been identified as having the poor metaboliser genotype, either (a) administering siponimod, or a pharmaceutically acceptable salt thereof, to the patient at a therapeutic dose below that of the standard therapeutic dose; or (b) not administering siponimod to the patient. (a) administering siponimod, or a pharmaceutically acceptable salt thereof, to the patient at a therapeutic dose below that of the standard therapeutic dose; or (b) not administering siponimod to the patient.
A motor rotor for a water pump, comprising: a hollow rotatable shaft having a first injection-molded part ; a magnet having an axial length and being disposed circumferentially around a portion of the first injection-molded part, wherein the portion of the first injection-molded part extends through the entire axial length of the magnet; an impeller integrally formed with the first injection-molded part, said impeller being located at an axial end of the hollow rotatable shaft; and characterized by : wherein the hollow rotatable shaft further comprises a second injection-molded part extending around the first injection-molded part and over the axial length of the magnet , the second injection-molded part cooperating with the first injection-molded part to fixedly clamp the magnet between the first injection-molded part and the second injection-molded part . a hollow rotatable shaft having a first injection-molded part ; a magnet having an axial length and being disposed circumferentially around a portion of the first injection-molded part, wherein the portion of the first injection-molded part extends through the entire axial length of the magnet; an impeller integrally formed with the first injection-molded part, said impeller being located at an axial end of the hollow rotatable shaft; and characterized by : wherein the hollow rotatable shaft further comprises a second injection-molded part extending around the first injection-molded part and over the axial length of the magnet , the second injection-molded part cooperating with the first injection-molded part to fixedly clamp the magnet between the first injection-molded part and the second injection-molded part .
A non-return valve mechanism mountable on a one-way valve device to regulate flow of a fluid, the one-way valve device including a flow channel in which the fluid flows and an on-off valve located in a middle portion of the flow channel and switchable between an open state and a closed state, the non-return valve mechanism being mountable in a mounting space (x) located downstream (Dd) from the on-off valve in the flow channel of the one-way valve device , the non-return valve mechanism comprising: a regulator valve movable forward and backward between a valve-closed position (Fig. 14B) and a valve-open position (Fig. 14C) in the mounting space (x), and movable backward to the valve-open position (Fig. 14C) under pressure of the fluid flowing upstream (Du); and a biasing member with a spring force to bias the regulator valve in a valve-closing direction from the valve-open position (Fig. 14C) to the valve-closed position (Fig. 14B), and to permit the regulator valve to move in a valve-opening direction from the valve-closed position (Fig. 14B) to the valve-open position (Fig. 14C) against the biasing in the valve-closing direction when the fluid flowing upstream has a predetermined pressure or greater, characterized in that the regulator valve includes, in an area of the regulator valve at the valve-closed position (Fig. 14B) communicating with an upstream space (Y), a valve-closing directional end for receiving a pressure (P) in the valve-closing direction and having a smaller projected area in an opening and closing direction than a valve-opening directional end for receiving a pressure (P) in the valve-opening direction. a regulator valve movable forward and backward between a valve-closed position (Fig. 14B) and a valve-open position (Fig. 14C) in the mounting space (x), and movable backward to the valve-open position (Fig. 14C) under pressure of the fluid flowing upstream (Du); and a biasing member with a spring force to bias the regulator valve in a valve-closing direction from the valve-open position (Fig. 14C) to the valve-closed position (Fig. 14B), and to permit the regulator valve to move in a valve-opening direction from the valve-closed position (Fig. 14B) to the valve-open position (Fig. 14C) against the biasing in the valve-closing direction when the fluid flowing upstream has a predetermined pressure or greater, characterized in that the regulator valve includes, in an area of the regulator valve at the valve-closed position (Fig. 14B) communicating with an upstream space (Y), a valve-closing directional end for receiving a pressure (P) in the valve-closing direction and having a smaller projected area in an opening and closing direction than a valve-opening directional end for receiving a pressure (P) in the valve-opening direction.
A method for controlling a gearless wind turbine , the wind turbine having a generator with a stator and a generator rotor and in between an air gap with an air gap thickness, wherein - the generator is designed as an internal rotor, with the stator as the outer part and the generator rotor as the inner part, or - the generator is designed as an external rotor, with the generator rotor as the outer part and the stator as the inner part, comprising the steps of: - detecting a temperature of the outer part as an outer part temperature (T A ), - detecting a temperature of the inner part as an inner part temperature (T I ), - forming a temperature difference as the difference between the outer part temperature and the inner part temperature, - controlling the generator in dependence on the temperature difference in such a way that a reduction in the air gap thickness due to thermal expansion of the generator is counteracted, characterized in that - the air gap thickness is monitored and, when a specifiable minimum thickness is undershot, a safety shutdown is initiated, in order to prevent contact between the outer part and the inner part, and - every time the safety shutdown is initiated, a overshooting temperature, which indicates a temperature value by which the outer part temperature is intended to lie above the inner part temperature, is increased, wherein - the overshooting temperature is reduced again step by step if the safety shutdown has not been initiated within a testing time period. - the generator is designed as an internal rotor, with the stator as the outer part and the generator rotor as the inner part, or - the generator is designed as an external rotor, with the generator rotor as the outer part and the stator as the inner part, comprising the steps of: - detecting a temperature of the outer part as an outer part temperature (T A ), - detecting a temperature of the inner part as an inner part temperature (T I ), - forming a temperature difference as the difference between the outer part temperature and the inner part temperature, - controlling the generator in dependence on the temperature difference in such a way that a reduction in the air gap thickness due to thermal expansion of the generator is counteracted, characterized in that - the air gap thickness is monitored and, when a specifiable minimum thickness is undershot, a safety shutdown is initiated, in order to prevent contact between the outer part and the inner part, and - every time the safety shutdown is initiated, a overshooting temperature, which indicates a temperature value by which the outer part temperature is intended to lie above the inner part temperature, is increased, wherein - the overshooting temperature is reduced again step by step if the safety shutdown has not been initiated within a testing time period.
Force measurement device , comprising: a first magnetic field generating unit configured to generate a magnetic field for being applied to a test object; a first magnetic field sensing unit configured to sense the generated magnetic field; a second magnetic field sensing unit configured to sense the generated magnetic field; a flux concentrator having a first pole , a second pole and a third pole ; a control unit ; wherein the first pole, the second pole and the third pole extend in the same direction; wherein the first magnetic field generating unit is arranged at the first pole; wherein the first magnetic field sensing unit is arranged at the second pole; wherein the second magnetic field sensing unit is a coil wound around the third pole; wherein a line enveloping a first end face of the first pole, a second end face of the second pole and a third end face of the third pole is concave shaped; wherein the control unit is adapted to determine a force applied to a test object based on the sensed magnetic field; wherein a cross section of the first pole is greater than a cross section of the second pole and greater than a cross section of the third pole; characterized in that a first connection line between the first pole and the second pole and a second connection line between the first pole and the third pole intersect at an angle between 80° and 100°. a first magnetic field generating unit configured to generate a magnetic field for being applied to a test object; a first magnetic field sensing unit configured to sense the generated magnetic field; a second magnetic field sensing unit configured to sense the generated magnetic field; a flux concentrator having a first pole , a second pole and a third pole ; a control unit ; wherein the first pole, the second pole and the third pole extend in the same direction; wherein the first magnetic field generating unit is arranged at the first pole; wherein the first magnetic field sensing unit is arranged at the second pole; wherein the second magnetic field sensing unit is a coil wound around the third pole; wherein a line enveloping a first end face of the first pole, a second end face of the second pole and a third end face of the third pole is concave shaped; wherein the control unit is adapted to determine a force applied to a test object based on the sensed magnetic field; wherein a cross section of the first pole is greater than a cross section of the second pole and greater than a cross section of the third pole; characterized in that a first connection line between the first pole and the second pole and a second connection line between the first pole and the third pole intersect at an angle between 80° and 100°.
A method of treating a maize or wheat plant with a triazole gibberellic acid-inhibitor, the method comprising administering the triazole to the plant by contacting the roots of the plant with the triazole prior to the formation of a visible reproductive structure: wherein the plant is treated at the V1, V2, V3, V4, or V5 stage and/or the plant is treated from about 5 days post germination to about 20 days post germination and the treatment induces tiller formation and/or increases tassel number; wherein the plant is treated at the V6, V7, V8, or V9 stage and/or the plant is treated from about 21 days post germination to about 35 days post germination and the treatment induces co-dominant ears on the main stem; and/or wherein the plant is treated at the V10, V11, or V12 stage and/or the plant is treated from about 35 days post germination to about 40 days post germination and wherein the treatment compresses the nodes above the primary ear, and wherein the treatment increases seed yield of the plant. wherein the plant is treated at the V6, V7, V8, or V9 stage and/or the plant is treated from about 21 days post germination to about 35 days post germination and the treatment induces co-dominant ears on the main stem; and/or wherein the plant is treated at the V10, V11, or V12 stage and/or the plant is treated from about 35 days post germination to about 40 days post germination and wherein the treatment compresses the nodes above the primary ear, and wherein the treatment increases seed yield of the plant.
A non-planar resistive memory cell, comprising: a substrate including two levels of interconnects (M1, M2) and an interconnect , all surrounded by a dielectric layer ; a first electrode disposed on opposing trench walls in an open region of the substrate over the interconnect and in contact with the interconnect ; a second electrode ; and a switching layer disposed between the first and second electrodes in the trench, the switching layer comprising at least one of a metal oxide and a metal oxide alloy; an oxygen exchange layer , OEL, between the switching layer and one of the first electrode and second electrode , the OEL extending above the memory cell; wherein the second electrode is substantially between opposing portions of the switching layer wherein the switching layer and the second electrode extend above and beyond the memory cell, a dielectric layer on the substrate, the dielectric layer comprising an interconnect in contact with the second electrode and an interconnect level M3 in contact with the two levels of interconnects (M1, M2). a substrate including two levels of interconnects (M1, M2) and an interconnect , all surrounded by a dielectric layer ; a first electrode disposed on opposing trench walls in an open region of the substrate over the interconnect and in contact with the interconnect ; a second electrode ; and a switching layer disposed between the first and second electrodes in the trench, the switching layer comprising at least one of a metal oxide and a metal oxide alloy; an oxygen exchange layer , OEL, between the switching layer and one of the first electrode and second electrode , the OEL extending above the memory cell; wherein the second electrode is substantially between opposing portions of the switching layer wherein the switching layer and the second electrode extend above and beyond the memory cell, a dielectric layer on the substrate, the dielectric layer comprising an interconnect in contact with the second electrode and an interconnect level M3 in contact with the two levels of interconnects (M1, M2).
A method comprising: providing a release liner having a release surface; printing an ink pattern onto the release surface of the release liner to form a passivation layer, the passivation layer including a pattern of passivation features projecting away from the release surface; and providing a layer of adhesive onto the release surface of the release liner, the passivation layer being sandwiched between the release liner and the layer of adhesive, wherein the passivation features are at least partially embedded in a major surface of the layer of adhesive such that when the release liner is peeled from the layer of adhesive, the passivation layer remains with the layer of adhesive to form one or more selected areas on the major surface of the layer of adhesive, the one or more selected areas having an adhesive functionality different from the remaining areas of the major surface of the layer of adhesive, wherein the passivation features have an exposed surface coplanar with the major surface of the layer of adhesive after the removal of the release liner. providing a release liner having a release surface; printing an ink pattern onto the release surface of the release liner to form a passivation layer, the passivation layer including a pattern of passivation features projecting away from the release surface; and providing a layer of adhesive onto the release surface of the release liner, the passivation layer being sandwiched between the release liner and the layer of adhesive, wherein the passivation features are at least partially embedded in a major surface of the layer of adhesive such that when the release liner is peeled from the layer of adhesive, the passivation layer remains with the layer of adhesive to form one or more selected areas on the major surface of the layer of adhesive, the one or more selected areas having an adhesive functionality different from the remaining areas of the major surface of the layer of adhesive, wherein the passivation features have an exposed surface coplanar with the major surface of the layer of adhesive after the removal of the release liner.
Method (C) for converting a data signal (U) to a converted signal (X), comprising processes of - providing an input symbol stream (IB) of input symbols (Bj), the input symbol stream (IB) being representative for the data signal (U) to be converted and - applying to consecutive disjunct partial input symbol sequences (IBP) of a number of p consecutive input symbols (IBj) covering said input symbol stream (IB), with p being a fixed natural number, a distribution matching process (DM) in order to generate and output a final output symbol stream (OB) or a preform thereof, wherein - the distribution matching process (DM) is formed by a preceding shell mapping process (SM) and a succeeding amplitude mapping process (AM), - said shell mapping process (SM) is configured in order to form and output to said amplitude mapping process (AM) for each of said consecutive partial input symbol sequences (IB p ) a sequence (s q ) of a number of q shell indices (s), with q being a fixed natural number, - said amplitude mapping process (AM) is configured to assign to each shell index (s) a tuple of amplitude values (Ar, Ai), and - said amplitude values (Ar, Ai) or a sequence thereof are supplied to a probabilistic amplitude shaping process (PAS) in order to thereby generate and output constellation points or a sequence thereof, respectively, as a final output symbol stream (OB) being representative for the converted signal (X) and in forward error corrected form. - providing an input symbol stream (IB) of input symbols (Bj), the input symbol stream (IB) being representative for the data signal (U) to be converted and - applying to consecutive disjunct partial input symbol sequences (IBP) of a number of p consecutive input symbols (IBj) covering said input symbol stream (IB), with p being a fixed natural number, a distribution matching process (DM) in order to generate and output a final output symbol stream (OB) or a preform thereof, wherein - the distribution matching process (DM) is formed by a preceding shell mapping process (SM) and a succeeding amplitude mapping process (AM), - said shell mapping process (SM) is configured in order to form and output to said amplitude mapping process (AM) for each of said consecutive partial input symbol sequences (IB p ) a sequence (s q ) of a number of q shell indices (s), with q being a fixed natural number, - said amplitude mapping process (AM) is configured to assign to each shell index (s) a tuple of amplitude values (Ar, Ai), and - said amplitude values (Ar, Ai) or a sequence thereof are supplied to a probabilistic amplitude shaping process (PAS) in order to thereby generate and output constellation points or a sequence thereof, respectively, as a final output symbol stream (OB) being representative for the converted signal (X) and in forward error corrected form.
A method for manufacturing a blade of composite material for a turbomachine, in particular for an aircraft, this blade comprising a vane comprising a pressure side and a suction side which extend from a leading edge to a trailing edge of the vane, the blade further comprising a metal sheath extending along the leading edge of the vane, the method comprising the steps consisting in: a) placing a preform made by weaving fibres in three dimensions in a mould, the sheath being positioned on an edge of the preform intended to form the leading edge of the vane, b) injecting polymerizable resin into the mould to impregnate the preform so as to form the vane after solidification, characterised in that at least one double-sided adhesive film , coated or soaked on its both faces with a glue so as to be adhesive on its both faces, is interposed between the sheath and the edge of the preform during the step a). a) placing a preform made by weaving fibres in three dimensions in a mould, the sheath being positioned on an edge of the preform intended to form the leading edge of the vane, b) injecting polymerizable resin into the mould to impregnate the preform so as to form the vane after solidification,
Motor vehicle door handle assembly for operating a motor vehicle door, with a deflection lever which is mounted so as to be rotatable about an axis and which, when rotated about the axis from a rest position to an operating position, acts directly or indirectly on a motor vehicle door lock in order to cause the lock to be released and allow the motor vehicle door to be opened, the motor vehicle door handle assembly having an abutment , which blocks the deflection lever after plastic deformation of the motor vehicle door handle arrangement, characterised in that the deflection lever has at least one latching element which, when an external force occurs as a result of an impact, engages with an accident lock and blocks displacement of the deflection lever from the rest position into its actuating position.
Polymerisable composition containing (a) at least one benzoxazine compound and (b) at least one phosphorus-containing polymer selected from polycarboxylic acid (thio)esters or polycarboxylic acid amides, wherein the phosphorus-containing polymer comprises at least one structural element of the general formula (I), wherein R a , R b , R c , R d , R e , R f , R g and R h are selected, independently of one another, from hydrogen, alkyl, aryl, alkoxy, aryloxy, aralkyl, halogen, cyanide, thiol, amine, carboxyl or acyl. (a) at least one benzoxazine compound and (b) at least one phosphorus-containing polymer selected from polycarboxylic acid (thio)esters or polycarboxylic acid amides, wherein the phosphorus-containing polymer comprises at least one structural element of the general formula (I), wherein R a , R b , R c , R d , R e , R f , R g and R h are selected, independently of one another, from hydrogen, alkyl, aryl, alkoxy, aryloxy, aralkyl, halogen, cyanide, thiol, amine, carboxyl or acyl.