mhurhangee/patent-ind-claim-en huggingface dataset:
A computer-implemented method for analyzing a bipartite graph data structure to condense reaction pathways of a metabolic network, comprising: Receiving a metabolic network in a bipartite graph data structure, comprising: a plurality of molecule nodes , wherein each molecule node comprises a molecule in a metabolic reaction; a plurality of edges connecting at least two of the plurality of molecule nodes, wherein each edge leading out of a first molecule node and into a second molecule node represents a metabolic reaction in which the first molecule is a reactant and the second molecule is a product; determining for each molecule node in the bipartite graph data structure a first number of metabolic reactions for which each molecule is a product based on a first number of edges leading into each molecule node; determining for each molecule node in the bipartite graph data structure a second number of metabolic reactions for which each molecule is a reactant based on a second number of edges leading out of each molecule node; and responsive to determining that none of the first number of edges leads into a third molecule node, or none of the second number of edges leads out of the third molecule node, blocking a first reaction pathway of all molecule nodes and edges connected to the third molecule node in the bipartite graph data structure. Receiving a metabolic network in a bipartite graph data structure, comprising: a plurality of molecule nodes , wherein each molecule node comprises a molecule in a metabolic reaction; a plurality of edges connecting at least two of the plurality of molecule nodes, wherein each edge leading out of a first molecule node and into a second molecule node represents a metabolic reaction in which the first molecule is a reactant and the second molecule is a product; a plurality of molecule nodes , wherein each molecule node comprises a molecule in a metabolic reaction; a plurality of edges connecting at least two of the plurality of molecule nodes, wherein each edge leading out of a first molecule node and into a second molecule node represents a metabolic reaction in which the first molecule is a reactant and the second molecule is a product; determining for each molecule node in the bipartite graph data structure a first number of metabolic reactions for which each molecule is a product based on a first number of edges leading into each molecule node; determining for each molecule node in the bipartite graph data structure a second number of metabolic reactions for which each molecule is a reactant based on a second number of edges leading out of each molecule node; and responsive to determining that none of the first number of edges leads into a third molecule node, or none of the second number of edges leads out of the third molecule node, blocking a first reaction pathway of all molecule nodes and edges connected to the third molecule node in the bipartite graph data structure.
A screening method for VEGF mRNAs with extended lifetime, said method comprising the following steps: i) performing pointwise deletions in the 3'-untranslated region (3'-UTR)of a VEGF gene, wherein the deleted nucleotide is either not substituted or substituted with cytosine at the substitution points of guanine and adenine, to produce a polynucleotide comprising said modified 3'-UTR sequence; ii) transcribing said polynucleotide into a mRNA transcript; iii) determining the mRNA lifetime of said mRNA transcript after each deletion; iv) analyzing said mRNA lifetime information. i) performing pointwise deletions in the 3'-untranslated region (3'-UTR)of a VEGF gene, wherein the deleted nucleotide is either not substituted or substituted with cytosine at the substitution points of guanine and adenine, to produce a polynucleotide comprising said modified 3'-UTR sequence; ii) transcribing said polynucleotide into a mRNA transcript; iii) determining the mRNA lifetime of said mRNA transcript after each deletion; iv) analyzing said mRNA lifetime information.
A gas turbine engine component comprising: an engine case structure surrounding an engine center axis (A); and a plurality of holes formed in the engine case structure , wherein the holes are circumferentially spaced apart from each other about the engine center axis (A); characterised in that : the plurality of holes include at least one balance hole configured to balance stiffness of the engine case structure and at least one service hole with an engine component passing through the at least one service hole with an air gap between an outer surface of the component passing through the service hole and the service hole perimeter such that cooling air is forced through the service hole to flow around and cool the component passing through the service hole ; and wherein at least one cover covers the at least one balance hole such that air is prevented from passing through the at least one balance hole ., wherein the cover is made from a flexible material. an engine case structure surrounding an engine center axis (A); and a plurality of holes formed in the engine case structure , wherein the holes are circumferentially spaced apart from each other about the engine center axis (A); the plurality of holes include at least one balance hole configured to balance stiffness of the engine case structure and at least one service hole with an engine component passing through the at least one service hole with an air gap between an outer surface of the component passing through the service hole and the service hole perimeter such that cooling air is forced through the service hole to flow around and cool the component passing through the service hole ; and wherein at least one cover covers the at least one balance hole such that air is prevented from passing through the at least one balance hole ., wherein the cover is made from a flexible material.
Ground working machine , in particular a road milling machine, stabiliser or the like, comprising a milling drum which is rotatably mounted on a machine frame and which is or can be equipped on its outer periphery with working tools , wherein the working tools are provided to come into contact with the ground to be worked during working operation in order to remove the same, wherein a drive unit is provided which drives the milling drum by means of a drive motor , wherein a drive shaft is connected to the milling drum and can be coupled to the drive motor , and wherein a ballast element is provided as a kinetic mass for increasing the kinetic energy of the milling drum , characterised in that the kinetic mass can be coupled or uncoupled to or from the rotatable milling drum or to or from a rotational member coupled directly or indirectly to the milling drum via a shiftable coupling . wherein a drive unit is provided which drives the milling drum by means of a drive motor , wherein a drive shaft is connected to the milling drum and can be coupled to the drive motor , and wherein a ballast element is provided as a kinetic mass for increasing the kinetic energy of the milling drum , characterised in that the kinetic mass can be coupled or uncoupled to or from the rotatable milling drum or to or from a rotational member coupled directly or indirectly to the milling drum via a shiftable coupling .
Cabin module for an aircraft, the cabin module having a sanitary unit ; wherein the sanitary unit has a toilet cubicle with a toilet ; wherein the toilet cubicle is formed by four side walls and the toilet is arranged on a first side wall ; wherein a first access door is arranged in a second side wall , which extends transversely to the first side wall and adjoins the first side wall; wherein a surface which is designed to at least partially accommodate a wheelchair is provided within the toilet cubicle; wherein the cabin module is configured to be installed with the second side wall transversely to the direction of flight; wherein the first side wall is aligned with an external wall in the installed state; wherein a second access door is arranged in a third side wall , which extends transversely to the second side wall and adjoins the second side wall; wherein the second and the third side wall are connected at right angles by a connection region ; wherein a connecting door is provided, which adjoins the connection region and is designed to separate from an aisle region a secondary access region , which is situated in front of the second access door, outside the toilet cubicle; wherein a frame structure is provided, which adjoins the toilet cubicle on a side opposite the first side wall; wherein the frame structure can be connected to a primary structure of a fuselage structure; wherein the frame structure has at least two vertical structural elements , which form a first frame side , which adjoins the second side wall and in which the connecting door is provided; and wherein at least the first access door and the connecting door are secured on the frame structure.
Tyre sidewall, having a rubber composition based on at least one diene elastomer, a reinforcing filler comprising carbon black and a sulphur-based crosslinking system, characterized in that the carbon black has a CTAB specific surface area greater than or equal to 90 m 2 /g and that the proportion of this carbon black is between 30 and 40 phr, the carbon black constituting the predominant reinforcing filler, and in which the rubber composition comprises from 35 to 55% of natural rubber or of synthetic polyisoprene, and from 65 to 45% of a diene elastomer chosen from polybutadiene, styrene-butadiene copolymers, isoprene-butadiene copolymers, isoprene-styrene copolymers and isoprene-butadiene-styrene copolymers.
A display device capable of displaying an aerial image using retroreflection, the display device comprising: a first optical structure configured to form a multiple image by light diffused or scattered by a first light diffusion surface of a first light guide layer ; a second optical structure configured to retroreflect light diffused or scattered by a second light diffusion surface of a second light guide layer to form an aerial image , characterized in that the first optical structure and the second optical structure are in a stacked relationship, and the first light diffusion surface and the second light diffusion surface are disposed at positions not overlapping each other. a first optical structure configured to form a multiple image by light diffused or scattered by a first light diffusion surface of a first light guide layer ; a second optical structure configured to retroreflect light diffused or scattered by a second light diffusion surface of a second light guide layer to form an aerial image , characterized in that the first optical structure and the second optical structure are in a stacked relationship, and the first light diffusion surface and the second light diffusion surface are disposed at positions not overlapping each other.
A dispenser for dispensing a sheet of web material from a stack of folded web material, the dispenser comprising: a web material storage section arranged to hold and support the stack of folded web material, in a generally vertical direction during dispensing of the web material; the web material storage section comprising an upper end portion a lower end portion , opposite to the upper end portion and being arranged to support the stack of folded web material in said generally vertical direction , at least when the dispenser is in said dispensing position, said upper end portion and lower end portion being arranged in a fixed spatial relationship; whereby the lower end portion of the web material storage section comprises - a loading opening and - a supporting arrangement , arranged to be movable between a support position wherein the supporting arrangement extends at least partially over said loading opening enabling said support of the stack of folded web material, and an insert position, wherein the supporting arrangement is at least partially removed from the loading opening; wherein said supporting arrangement is arranged to be movable from said support position to said insert position by pushing a stack to be introduced in the loading opening towards the supporting arrangement in a direction towards the upper end portion of the web material storage section , characterized in that the web material is arranged to be lead from the upper end portion for dispensing thereof. a web material storage section arranged to hold and support the stack of folded web material, in a generally vertical direction during dispensing of the web material; the web material storage section comprising an upper end portion a lower end portion , opposite to the upper end portion and being arranged to support the stack of folded web material in said generally vertical direction , at least when the dispenser is in said dispensing position, said upper end portion and lower end portion being arranged in a fixed spatial relationship; whereby the lower end portion of the web material storage section comprises - a loading opening and - a supporting arrangement , arranged to be movable between a support position wherein the supporting arrangement extends at least partially over said loading opening enabling said support of the stack of folded web material, and - a loading opening and - a supporting arrangement , arranged to be movable between a support position wherein the supporting arrangement extends at least partially over said loading opening enabling said support of the stack of folded web material, and an insert position, wherein the supporting arrangement is at least partially removed from the loading opening; wherein said supporting arrangement is arranged to be movable from said support position to said insert position by pushing a stack to be introduced in the loading opening towards the supporting arrangement in a direction towards the upper end portion of the web material storage section , characterized in that the web material is arranged to be lead from the upper end portion for dispensing thereof.
A therapeutic compound comprising an agent that inhibits the activity of FOXS1 gene, wherein said agent is selected from the group consisting of: anti-sense DNA or RNA, siRNA, shRNA, TALENS or ribozymes, either naked or in the form of plasmid or viral vectors, and antibodies, for use in the prevention and/or treatment of mammalian fibrosis, hypertrophic scar or keloid.
Assembly of a vehicle seat comprising a seat cushion and a backrest and of a safety belt comprising an upper-body strap and a lap strap as well as a seatbelt buckle tongue , wherein the seat comprises at least one airbag and a flexible retaining wall which are incorporated into the backrest of said seat , said airbag being fixed to said wall such that when the vehicle is involved in an impact with an external obstacle, the flexible retaining wall can deploy along the lap strap between the backrest and the upper-body strap and so that the airbag can inflate between the backrest and the flexible retaining wall while being driven into position by said flexible wall , characterized in that the lap strap acts as a guideway for the deployment of the flexible retaining wall .
A sun umbrella capable of emitting light in all directions comprising: an umbrella rod , and an umbrella disc, wherein the umbrella rod is connected to an opening-and-closing device , and is internally provided with a light strip, wherein circuit boards are fixedly assembled in the umbrella disc, wherein the opening-and-closing device comprises a plurality of light-transmitting tubes, wherein each light-transmitting tube is internally provided with a light strip, and the light strip is electrically connected to a power supply through a circuit board; wherein the light strip comprises a plurality of copper-wire lights , which are connected in series through an electric wire , wherein the tail end of the electric wire is connected to a connecting block for connecting the circuit board; characterised in that the umbrella rod is internally provided with a third light strip , wherein the umbrella disc comprises an upper umbrella disc and a lower umbrella disc, and a first circuit board and a second circuit board are respectively fixedly assembled in the upper umbrella disc and the lower umbrella disc, wherein the light-transmitting tubes comprise a first light-transmitting tube and a second light-transmitting tube which are hinged through a hinge member , wherein the first light-transmitting tube and the second light-transmitting tube are respectively internally provided with a first light strip and a second light strip . an umbrella rod , and an umbrella disc, wherein the umbrella rod is connected to an opening-and-closing device , and is internally provided with a light strip, wherein circuit boards are fixedly assembled in the umbrella disc, wherein the opening-and-closing device comprises a plurality of light-transmitting tubes, wherein each light-transmitting tube is internally provided with a light strip, and the light strip is electrically connected to a power supply through a circuit board; wherein the light strip comprises a plurality of copper-wire lights , which are connected in series through an electric wire , wherein the tail end of the electric wire is connected to a connecting block for connecting the circuit board; characterised in that the umbrella rod is internally provided with a third light strip , wherein the umbrella disc comprises an upper umbrella disc and a lower umbrella disc, and a first circuit board and a second circuit board are respectively fixedly assembled in the upper umbrella disc and the lower umbrella disc, wherein the light-transmitting tubes comprise a first light-transmitting tube and a second light-transmitting tube which are hinged through a hinge member , wherein the first light-transmitting tube and the second light-transmitting tube are respectively internally provided with a first light strip and a second light strip .
A method comprising: obtaining geographic position data of a device; identifying a current geographic location of the device based on the geographic position data; obtaining temporal data that is related to the geographic position data, wherein the temporal data identifies a current time of day at the current geographic location of the device; and selecting , from a history of operational modes selected for activation on the device for a particular time period of the day that corresponds to the current time of day, an operational mode for activation on the device, based on the current time of day and the current geographic location of the device, characterized in that the history of operational modes includes operational modes associated with a connection success confidence value exceeding a threshold value and defined by a ratio of successful connections to connection attempts, or one or more signal strength values associated with the current geographical location of the device. obtaining geographic position data of a device; identifying a current geographic location of the device based on the geographic position data; obtaining temporal data that is related to the geographic position data, wherein the temporal data identifies a current time of day at the current geographic location of the device; and selecting , from a history of operational modes selected for activation on the device for a particular time period of the day that corresponds to the current time of day, an operational mode for activation on the device, based on the current time of day and the current geographic location of the device, characterized in that the history of operational modes includes operational modes associated with a connection success confidence value exceeding a threshold value and defined by a ratio of successful connections to connection attempts, or one or more signal strength values associated with the current geographical location of the device.
A computer-implemented method executed by one or more processors, the method comprising: during execution of a software application by a processor , receiving , by a copy processor , which is separate from the processor, a request for an asynchronous data copy operation to copy data within a memory accessible by the copy processor, wherein the request is received from a copy manager accessible by the software application in a user space of an operating system managing execution of the software application, wherein the request includes a notification indication indicating how a notification that the asynchronous data copy operation has completed is to be handled, wherein the handling comprises setting a completion flag or passing an interrupt to the copy manager, and wherein the notification indication indicates that the copy processor should pass an interrupt to the copy manager upon completion of the asynchronous data copy operation; in response to the request, initiating , by the copy processor, the asynchronous data copy operation; continuing execution of the software application by the processor; determining , by the copy processor, that the asynchronous data copy operation has completed; and in response to determining that the asynchronous data copy operation has completed, selectively notifying , by the copy processor, the software application that the asynchronous data copy operation has completed, wherein, based on the notification indication in the request, the selectively notifying comprises the passing of the interrupt to the copy manager, which communicates with the software application. during execution of a software application by a processor , receiving , by a copy processor , which is separate from the processor, a request for an asynchronous data copy operation to copy data within a memory accessible by the copy processor, wherein the request is received from a copy manager accessible by the software application in a user space of an operating system managing execution of the software application, wherein the request includes a notification indication indicating how a notification that the asynchronous data copy operation has completed is to be handled, wherein the handling comprises setting a completion flag or passing an interrupt to the copy manager, and wherein the notification indication indicates that the copy processor should pass an interrupt to the copy manager upon completion of the asynchronous data copy operation; in response to the request, initiating , by the copy processor, the asynchronous data copy operation; continuing execution of the software application by the processor; determining , by the copy processor, that the asynchronous data copy operation has completed; and in response to determining that the asynchronous data copy operation has completed, selectively notifying , by the copy processor, the software application that the asynchronous data copy operation has completed, wherein, based on the notification indication in the request, the selectively notifying comprises the passing of the interrupt to the copy manager, which communicates with the software application.