A biomedical device for the therapeutic treatment of ulcers or lesions, particularly diabetic ulcers, said device consisting of a kit comprising in combination an electro-stimulator device and a dressing comprising a pharmaceutical composition and wherein the electro-stimulating device and the said dressing are applied simultaneously for treating an ulcer and which device comprises: - at least an electrical pulses generator , said electrical pulses being organized in sequences of electrical pulses having prefixed values of typical parameters, said typical parameters comprising one or more of the following parameters: amplitude, duration, frequency and/or waveform of said pulses and said parameters being configured according to the technology called FREMS acronym for Frequency Rhythmic Electric Modulation; - said generator comprising at least two separate stimulation channels, through which said sequences are delivered to body areas of an organism independently for each channel; - at least two stimulation electrodes , each of which is connected or connectable to a respective stimulation channel and each of which is intended to be removably applied to one of two different prefixed body zones of an organism; - each electrode being applied externally to the patient's skin in correspondence with said prefixed area and with a prefixed position relationship with respect to the position of the remaining electrode or electrodes; - a control unit (14; 130) of said at least one electric pulse generator communicating with said electric pulse generator; - a command and/or data entry interface for setting and/or displaying setting data and/or setting settings of said one or more generator ; - said dressing consisting of a film comprising a solution of povidone iodine (PVP-I) and sodium alginate (NaAlq) and intended to be applied while treating the ulcer; and wherein - the at least two electrodes are intended to be arranged on diametrically opposite sides of the lesion at a prefixed distance therefrom. - at least an electrical pulses generator , said electrical pulses being organized in sequences of electrical pulses having prefixed values of typical parameters, said typical parameters comprising one or more of the following parameters: amplitude, duration, frequency and/or waveform of said pulses and said parameters being configured according to the technology called FREMS acronym for Frequency Rhythmic Electric Modulation; - said generator comprising at least two separate stimulation channels, through which said sequences are delivered to body areas of an organism independently for each channel; - at least two stimulation electrodes , each of which is connected or connectable to a respective stimulation channel and each of which is intended to be removably applied to one of two different prefixed body zones of an organism; - each electrode being applied externally to the patient's skin in correspondence with said prefixed area and with a prefixed position relationship with respect to the position of the remaining electrode or electrodes; - a control unit (14; 130) of said at least one electric pulse generator communicating with said electric pulse generator; - a command and/or data entry interface for setting and/or displaying setting data and/or setting settings of said one or more generator ; - said dressing consisting of a film comprising a solution of povidone iodine (PVP-I) and sodium alginate (NaAlq) and intended to be applied while treating the ulcer; - the at least two electrodes are intended to be arranged on diametrically opposite sides of the lesion at a prefixed distance therefrom. <EOS>