mhurhangee/patent-ind-claim-en huggingface dataset:
Fast dispersible pharmaceutical composition in the form of tablet(s), said fast dispersible pharmaceutical composition comprising tyrosine-kinase inhibitor with at least one pharmaceutically acceptable excipient intended to be dispersed in water and/or other aqueous liquids before oral administration, wherein said tyrosine kinase inhibitor is monomesylate salt of imatinib, wherein a combination of lubricants sodium stearyl fumarate and magnesium stearate or sodium stearyl fumarate as lubricant is used, and wherein a combination of at least two disintegrants is used, said fast dispersible pharmaceutical composition being characterized with disintegration time of less than 3 minutes using purified water at 25°C, the disintegration test being carried out in accordance with European Pharmacopoeia 8.0, and characterized in that in the combination of at least two disintegrants calcium silicate is one of the disintegrants, a combination of crospovidone and calcium silicate being used, and in that the proportion of active ingredient is between 5 and 50 % by weight of the final composition, and in that a mixture of at least one water insoluble and at least one water soluble diluent is used. wherein said tyrosine kinase inhibitor is monomesylate salt of imatinib, wherein a combination of lubricants sodium stearyl fumarate and magnesium stearate or sodium stearyl fumarate as lubricant is used, and wherein a combination of at least two disintegrants is used, said fast dispersible pharmaceutical composition being characterized with disintegration time of less than 3 minutes using purified water at 25°C, the disintegration test being carried out in accordance with European Pharmacopoeia 8.0, and characterized in that in the combination of at least two disintegrants calcium silicate is one of the disintegrants, a combination of crospovidone and calcium silicate being used, and in that the proportion of active ingredient is between 5 and 50 % by weight of the final composition, and in that a mixture of at least one water insoluble and at least one water soluble diluent is used.
A ligand characterized by a general formula I: R 1 -D-X-D-X-D-X-D-E-R 2 (I) , wherein - D is C(O)N(OH) or N(OH)C(O), or in particular D is (in text: C(O)N(OH)), - each X independently of any other X is a saturated or partially unsaturated, substituted or unsubstituted linker comprising a chain of 9 to 11 atoms selected from any of N, C, O - R 1 is a H, C 1 -C 5 alkyl, a C 3 -C 6 cycloalkyl, an arene, and/or a heteroarene, - E is a linker comprising 1 - 50 atoms selected from C, O, N and S, and - R 2 is a) OH, NH 2 , SH, COOH, CHO, N 3 , SCN, CH 2 X, activated ester, an ene-one-system, a diene/dienophile, an alkene, or an alkyne, with X being Cl, Br or I, or b) a first click moiety capable of forming a covalent bond selectively with a second click moiety R 3 under reaction conditions not leading to a covalent reaction of R 2 or R 3 with natural occurring polypeptides, in particular said click moiety R 2 is selected from an azide, an alkyne, a tetrazine, a cyclooctine and a trans-cyclooctene. - D is C(O)N(OH) or N(OH)C(O), or in particular D is (in text: C(O)N(OH)), - each X independently of any other X is a saturated or partially unsaturated, substituted or unsubstituted linker comprising a chain of 9 to 11 atoms selected from any of N, C, O - R 1 is a H, C 1 -C 5 alkyl, a C 3 -C 6 cycloalkyl, an arene, and/or a heteroarene, - E is a linker comprising 1 - 50 atoms selected from C, O, N and S, and - R 2 is a) OH, NH 2 , SH, COOH, CHO, N 3 , SCN, CH 2 X, activated ester, an ene-one-system, a diene/dienophile, an alkene, or an alkyne, with X being Cl, Br or I, or b) a first click moiety capable of forming a covalent bond selectively with a second click moiety R 3 under reaction conditions not leading to a covalent reaction of R 2 or R 3 with natural occurring polypeptides, in particular said click moiety R 2 is selected from an azide, an alkyne, a tetrazine, a cyclooctine and a trans-cyclooctene. a) OH, NH 2 , SH, COOH, CHO, N 3 , SCN, CH 2 X, activated ester, an ene-one-system, a diene/dienophile, an alkene, or an alkyne, with X being Cl, Br or I, or b) a first click moiety capable of forming a covalent bond selectively with a second click moiety R 3 under reaction conditions not leading to a covalent reaction of R 2 or R 3 with natural occurring polypeptides, in particular said click moiety R 2 is selected from an azide, an alkyne, a tetrazine, a cyclooctine and a trans-cyclooctene.
One or more non-transitory computer-readable media storing instructions executed by one or more processors to perform a sequence comprising: detecting shot boundaries to segment video, wherein each segment includes a plurality of frames; for each frame of a set, V , of frames in a segment, determining a set of features of the frame using an object detection technique to compute a feature vector for each frame of the set of frames; for each frame of the set of frames, determining a coverage score as: c i = max w ij ; j ∈ V , where c is a coverage vector for the set of frames V, w ij is a measure of similarity between a pair of frames i and j in V,; joining the coverage vector, c, with coverage scores of a set of frames previously selected from the plurality of frames as summary frames for the video so that the coverage vector, c, encompasses candidate frames, where the candidate frames are the frames of the set of frames and the set of frames previously selected; for each frame of the candidate frames, compute a diversity score as: D i j = d ij where D is a diversity matrix, d ij is a distance metric between frames i and j based on the feature vectors, where each of frames i and j are in the candidate frames; and selecting summary frames from the set of frames, V, and the set of previously selected frames, the selecting based on an optimization vector x, that satisfies: max x c T x + 1 2 x T D x where x T is the transpose of x , x i ∈ ∀ i , with ∑ i = 1 n + k x i = k , where there are n frames in the set of frames and k frames in the set of previously selected frames. detecting shot boundaries to segment video, wherein each segment includes a plurality of frames; for each frame of a set, V , of frames in a segment, determining a set of features of the frame using an object detection technique to compute a feature vector for each frame of the set of frames; for each frame of the set of frames, determining a coverage score as: c i = max w ij ; j ∈ V , where c is a coverage vector for the set of frames V, w ij is a measure of similarity between a pair of frames i and j in V,; joining the coverage vector, c, with coverage scores of a set of frames previously selected from the plurality of frames as summary frames for the video so that the coverage vector, c, encompasses candidate frames, where the candidate frames are the frames of the set of frames and the set of frames previously selected; for each frame of the candidate frames, compute a diversity score as: D i j = d ij where D is a diversity matrix, d ij is a distance metric between frames i and j based on the feature vectors, where each of frames i and j are in the candidate frames; and selecting summary frames from the set of frames, V, and the set of previously selected frames, the selecting based on an optimization vector x, that satisfies: max x c T x + 1 2 x T D x where x T is the transpose of x , x i ∈ ∀ i , with ∑ i = 1 n + k x i = k , where there are n frames in the set of frames and k frames in the set of previously selected frames.
An inductive-capacitive filter assembly , comprising a plurality of insulating-conductive strips , concentrically wound around a winding axis , each of the insulating-conductive strips, firstly, having an insulating strip joined with a conductive strip and, secondly, forming a respective inductive-capacitive filter with a resonant frequency, and, thirdly, implementing a band stop filter which blocks signals with frequencies within a certain frequency band centered around the respective inductive capacitive filter's resonant frequency when connected to a power source at a first terminal end of the conductive strip and to a load connected to a second terminal end of the conductive strip.
An additive manufacturing method, comprising: electronically segmenting an electronic file representative of a component along a build interface to define at least a first component segment and a second component segment , so that each of the first component segment and the second component segment are sized to fit within an additive manufacturing build chamber ; simultaneously additive manufacturing the first component segment and the second component segment within the additive manufacturing build chamber ; welding the first component segment and the second component segment to form the component ; adding sacrificial material to the first component segment and/or the second component segment beyond the build interface ; and removing the sacrificial material during said welding. electronically segmenting an electronic file representative of a component along a build interface to define at least a first component segment and a second component segment , so that each of the first component segment and the second component segment are sized to fit within an additive manufacturing build chamber ; simultaneously additive manufacturing the first component segment and the second component segment within the additive manufacturing build chamber ; welding the first component segment and the second component segment to form the component ; adding sacrificial material to the first component segment and/or the second component segment beyond the build interface ; and removing the sacrificial material during said welding.
A laundry treating apparatus comprising: a cabinet ; a drum provided inside the cabinet and formed of a metal material for accommodating a treatment target; and an induction module inducing and heating the drum through a magnetic field generated as a current is applied to a coil in which a wire is wound, wherein the induction module includes: a base housing for accommodating the coil ; a cover housing comprising a through portion for discharging heat generated from the coil ; a permanent magnet housing provided between the base housing and the cover housing , jointed to an upper portion of the base housing and comprising a plurality of holders in which permanent magnets are accommodated, a connector provided with through portions for connecting the plurality of holders and a through portion communicated with the through portion of the cover housing . a cabinet ; a drum provided inside the cabinet and formed of a metal material for accommodating a treatment target; and an induction module inducing and heating the drum through a magnetic field generated as a current is applied to a coil in which a wire is wound, wherein the induction module includes: a base housing for accommodating the coil ; a cover housing comprising a through portion for discharging heat generated from the coil ; a permanent magnet housing provided between the base housing and the cover housing , jointed to an upper portion of the base housing and comprising a plurality of holders in which permanent magnets are accommodated, a connector provided with through portions for connecting the plurality of holders and a through portion communicated with the through portion of the cover housing . a base housing for accommodating the coil ; a cover housing comprising a through portion for discharging heat generated from the coil ; a permanent magnet housing provided between the base housing and the cover housing , jointed to an upper portion of the base housing and comprising a plurality of holders in which permanent magnets are accommodated, a connector provided with through portions for connecting the plurality of holders and a through portion communicated with the through portion of the cover housing .
A device to operate several functions in a motor vehicle, with an actuating element which is mounted on a rotary shaft so that it can swivel and can be moved between at least two positions, with a switching function allocated to at least one of the positions, so that different functions can be initiated by manual actuations of the actuating element whereby the actuating element is located centrally at a bearing point in relation to the direction of the vertical axis (z) and whereby the end-sections of the rotary shaft to the actuating element are mounted at two lateral bearing points in two slots directed along an vertical axis (z), characterized by the fact that when operated the actuating element gives a tactile feedback via an electromagnetic actuator which displaces the actuating element temporarily in the axial direction (y) of the rotary shaft , the actuating element is held centrally at a middle bearing point , where the middle bearing point is held at the upper and lower sides of the operating strip by centering pegs made up of two housing sections which are aligned on both sides of the actuating element along the vertical axis (z) and the actuating element is supported on the swivel studs by at least two articulated links and floats on these.
A method performed by a User Equipment, in the following also referred to as UE, the method comprising: receiving an indication from a base station, wherein: the indication is indicative of monitoring a power saving signal in one or more monitoring occasions; and at least one monitoring occasion of the one or more monitoring occasions is associated with a Discontinuous Reception, in the following also referred to as DRX, ON duration and is within Active Time associated with the UE; and monitoring a Physical Downlink Control Channel, in the following also referred to as PDCCH, during the DRX ON duration, characterized by at least one of not monitoring or skipping monitoring the power saving signal in the at least one monitoring occasion. receiving an indication from a base station, wherein: the indication is indicative of monitoring a power saving signal in one or more monitoring occasions; and at least one monitoring occasion of the one or more monitoring occasions is associated with a Discontinuous Reception, in the following also referred to as DRX, ON duration and is within Active Time associated with the UE; and the indication is indicative of monitoring a power saving signal in one or more monitoring occasions; and at least one monitoring occasion of the one or more monitoring occasions is associated with a Discontinuous Reception, in the following also referred to as DRX, ON duration and is within Active Time associated with the UE; and monitoring a Physical Downlink Control Channel, in the following also referred to as PDCCH, during the DRX ON duration, characterized by at least one of not monitoring or skipping monitoring the power saving signal in the at least one monitoring occasion.
A method of producing hydrocarbons comprising: (a) obtaining one or more samples from a well in a region of interest; (b) analyzing the sample to determine a ratio of at least two isotopes of a first metal; (c) analyzing the sample to determine a ratio of at least two isotopes of a second metal; (d) analyzing the sample to determine a ratio of at least two isotopes of a third metal; (e) integrating the isotope ratios of the first metal, second metal, and third metal to form a multiple metal isotope signature; (f) using the multiple metal isotope signature in bulk and compound specific metal isotope ratios to determine one or more of type of hydrocarbon in the subsurface accumulation, quality of hydrocarbon in the subsurface accumulation, and source of the hydrocarbon; and (g) developing or refining a hydrocarbon exploration, hydrocarbon development, or hydrocarbon production strategy based on the determined one or more of type of hydrocarbon, quality of hydrocarbon, and source of the hydrocarbon. (a) obtaining one or more samples from a well in a region of interest; (b) analyzing the sample to determine a ratio of at least two isotopes of a first metal; (c) analyzing the sample to determine a ratio of at least two isotopes of a second metal; (d) analyzing the sample to determine a ratio of at least two isotopes of a third metal; (e) integrating the isotope ratios of the first metal, second metal, and third metal to form a multiple metal isotope signature; (f) using the multiple metal isotope signature in bulk and compound specific metal isotope ratios to determine one or more of type of hydrocarbon in the subsurface accumulation, quality of hydrocarbon in the subsurface accumulation, and source of the hydrocarbon; and (g) developing or refining a hydrocarbon exploration, hydrocarbon development, or hydrocarbon production strategy based on the determined one or more of type of hydrocarbon, quality of hydrocarbon, and source of the hydrocarbon.
Electric motor , which comprises a stator ; which stator comprises slots , into which slots a concentrated winding is fitted; and which electric motor comprises a rotating rotor ; which rotor comprises arrow-shaped permanent magnets placed consecutively in a ring in the direction of the rotational movement, while an air gap between the stator and the rotor is essentially in the direction of the axis of rotation of the rotor; characterised in that a width of the permanent magnet is increasing with an increasing distance from the axis of rotation of the rotor, and that the ratio L M L P of a width of said permanent magnet at the center line of the magnet and a width (L P ) of the magnetic pole of the rotor is at least 2 3 and at most 4 5 . and which electric motor comprises a rotating rotor ; which rotor comprises arrow-shaped permanent magnets placed consecutively in a ring in the direction of the rotational movement, while an air gap between the stator and the rotor is essentially in the direction of the axis of rotation of the rotor; characterised in that a width of the permanent magnet is increasing with an increasing distance from the axis of rotation of the rotor, and that the ratio L M L P of a width of said permanent magnet at the center line of the magnet and a width (L P ) of the magnetic pole of the rotor is at least 2 3 and at most 4 5 .
An apparatus for use on a structural member having a longitudinal axis, the structural member being configured to propagate stress wave energy in an operational state, the stress wave energy having an operational frequency spectrum, the apparatus comprising: a housing assembly including a first end, a second end, and at least one protective enclosure configured to accommodate at least one device , the housing assembly being configured to be rotationally registered to the structural member when coupled to the structural member, the housing assembly having a predetermined housing mass; and a spring arrangement coupled between the structural member and the first end and/or coupled between the structural member and the second end in the operational state, the spring arrangement having a predetermined force-displacement relationship, the housing assembly and the spring arrangement forming an isolation filter having a predetermined spectral transfer function, the predetermined spectral transfer function being a function of the predetermined housing mass and the predetermined force-displacement relationship, the predetermined spectral transfer function including a passband having frequencies that are substantially outside the operational frequency spectrum wherein the stress wave energy is substantially attenuated in the operational state so that the housing assembly is substantially isolated from the stress wave energy. a housing assembly including a first end, a second end, and at least one protective enclosure configured to accommodate at least one device , the housing assembly being configured to be rotationally registered to the structural member when coupled to the structural member, the housing assembly having a predetermined housing mass; and a spring arrangement coupled between the structural member and the first end and/or coupled between the structural member and the second end in the operational state, the spring arrangement having a predetermined force-displacement relationship, the housing assembly and the spring arrangement forming an isolation filter having a predetermined spectral transfer function, the predetermined spectral transfer function being a function of the predetermined housing mass and the predetermined force-displacement relationship, the predetermined spectral transfer function including a passband having frequencies that are substantially outside the operational frequency spectrum wherein the stress wave energy is substantially attenuated in the operational state so that the housing assembly is substantially isolated from the stress wave energy.
A computer-aided machining method comprising: A) providing a material batch (M) with an undetermined machinability to a machining tool (MT), B) specifying a set of machining (c1) conditions comprising a machining speed, characterized in that the computer-aided machining method further comprises the steps: C) inserting a tool (TL) into the machining tool (MT), wherein the inserted tool (TL) is of a predetermined type and has a predetermined wear, D) machining the material batch (M) with the machining tool (MT), monitoring wear of the inserted tool (TL) during the machining, and determining a first tool life ( Tc 1) of the tool (TL), E) repeating Steps B, C and D to determine a second tool life (Tc2), while setting a different machining speed in Step B and inserting a tool of the same type in Step C, F) based on the machining speed, the different machining speed, the first and the second tool life ( Tc 1, Tc 2), determining coefficients of a model associated with the material batch (M), G) determining machinability of the material batch (M) based on the model. A) providing a material batch (M) with an undetermined machinability to a machining tool (MT), B) specifying a set of machining (c1) conditions comprising a machining speed, C) inserting a tool (TL) into the machining tool (MT), wherein the inserted tool (TL) is of a predetermined type and has a predetermined wear, D) machining the material batch (M) with the machining tool (MT), monitoring wear of the inserted tool (TL) during the machining, and determining a first tool life ( Tc 1) of the tool (TL), E) repeating Steps B, C and D to determine a second tool life (Tc2), while setting a different machining speed in Step B and inserting a tool of the same type in Step C, F) based on the machining speed, the different machining speed, the first and the second tool life ( Tc 1, Tc 2), determining coefficients of a model associated with the material batch (M), G) determining machinability of the material batch (M) based on the model.