A compound of Formula (I) N-oxide, stereoisomers, tautomers, solvates or a salt thereof, wherein: L is -L 1 -NR x C(O)-(CH 2 )t-C(O)NR x -L 2 -; L 1 and L 2 are independently -(CH 2 ) 1-3 -; t is an integer in the range of 2 to 24; G 1 and G 2 are each: R 1a and R 1b are independently H, Cl, -CN, C 1-4 alkyl, C 1-3 fluoroalkyl, C 1-3 hydroxyalkyl, C 1-3 hydroxy-fluoroalkyl, C 3-6 cycloalkyl, -CH 2 (C 3-6 cycloalkyl), -C(O)O(C 1-3 alkyl), or tetrahydropyranyl; each R 2 is independently halo, -CN, -OH, -NO 2 , C 1-4 alkyl, C 1 - 2 fluoroalkyl, C 1 - 2 cyanoalkyl, C 1-3 hydroxyalkyl, C 1-3 aminoalkyl, -O(CH 2 ) 1-2 OH, -(CH 2 ) 0-4 O(C 1-4 alkyl), C 1-3 fluoroalkoxy, -(CH 2 ) 1-4 O(C 1-3 alkyl), -O(CH 2 ) 1-2 OC(O)(C 1-3 alkyl), -O(CH 2 ) 1-2 NR x R x , -C(O)O(C 1-3 alkyl), -(CH 2 ) 0-2 C(O)NR y R y , -C(O)NR x (C 1-5 hydroxyalkyl), -C(O)NR x (C 2-6 alkoxyalkyl), -C(O)NR x (C 3-6 cycloalkyl), -NR y R y , -NR y (C 1-3 fluoroalkyl), -NR y (C 1-4 hydroxyalkyl), -NR x CH 2 (phenyl), -NR x S(O) 2 (C 3-6 cycloalkyl), -NR x C(O)(C 1-3 alkyl), -NR x CH 2 (C 3-6 cycloalkyl), -(CH 2 ) 0-2 S(O) 2 (C 1-3 alkyl), -(CH 2 ) 0-2 (C 3-6 cycloalkyl), -(CH 2 ) 0-2 (phenyl), morpholinyl, dioxothiomorpholinyl, dimethyl pyrazolyl, methylpiperidinyl, methylpiperazinyl, amino-oxadiazolyl, imidazolyl, triazolyl, or -C(O)(thiazolyl); each R 4 is independently F, -OH, C 1 - 2 alkyl, or -OCH 3 ; or two R 4 attached to the same carbon atom form =O; or wherein when m or n is at least 2, two R 4 , each attached to a different carbon atom adjacent to the nitrogen atom in a piperidinyl ring, can form a -CH 2 CH 2 - bridge; each R 5 is independently F, Cl, -CN, C 1-3 alkyl, C 1 - 2 fluoroalkyl, or -OCH 3 ; each R x is independently H or -CH 3 ; each R y is independently H or C 1-6 alkyl; m is zero, 1, 2, 3, or 4; n is zero, 1, 2, 3, or 4; each p is independently zero, 1, 2, 3, or 4; x is zero, 1, or 2; and y is zero, 1, or 2. L is -L 1 -NR x C(O)-(CH 2 )t-C(O)NR x -L 2 -; L 1 and L 2 are independently -(CH 2 ) 1-3 -; t is an integer in the range of 2 to 24; G 1 and G 2 are each: R 1a and R 1b are independently H, Cl, -CN, C 1-4 alkyl, C 1-3 fluoroalkyl, C 1-3 hydroxyalkyl, C 1-3 hydroxy-fluoroalkyl, C 3-6 cycloalkyl, -CH 2 (C 3-6 cycloalkyl), -C(O)O(C 1-3 alkyl), or tetrahydropyranyl; each R 2 is independently halo, -CN, -OH, -NO 2 , C 1-4 alkyl, C 1 - 2 fluoroalkyl, C 1 - 2 cyanoalkyl, C 1-3 hydroxyalkyl, C 1-3 aminoalkyl, -O(CH 2 ) 1-2 OH, -(CH 2 ) 0-4 O(C 1-4 alkyl), C 1-3 fluoroalkoxy, -(CH 2 ) 1-4 O(C 1-3 alkyl), -O(CH 2 ) 1-2 OC(O)(C 1-3 alkyl), -O(CH 2 ) 1-2 NR x R x , -C(O)O(C 1-3 alkyl), -(CH 2 ) 0-2 C(O)NR y R y , -C(O)NR x (C 1-5 hydroxyalkyl), -C(O)NR x (C 2-6 alkoxyalkyl), -C(O)NR x (C 3-6 cycloalkyl), -NR y R y , -NR y (C 1-3 fluoroalkyl), -NR y (C 1-4 hydroxyalkyl), -NR x CH 2 (phenyl), -NR x S(O) 2 (C 3-6 cycloalkyl), -NR x C(O)(C 1-3 alkyl), -NR x CH 2 (C 3-6 cycloalkyl), -(CH 2 ) 0-2 S(O) 2 (C 1-3 alkyl), -(CH 2 ) 0-2 (C 3-6 cycloalkyl), -(CH 2 ) 0-2 (phenyl), morpholinyl, dioxothiomorpholinyl, dimethyl pyrazolyl, methylpiperidinyl, methylpiperazinyl, amino-oxadiazolyl, imidazolyl, triazolyl, or -C(O)(thiazolyl); each R 4 is independently F, -OH, C 1 - 2 alkyl, or -OCH 3 ; or two R 4 attached to the same carbon atom form =O; or wherein when m or n is at least 2, two R 4 , each attached to a different carbon atom adjacent to the nitrogen atom in a piperidinyl ring, can form a -CH 2 CH 2 - bridge; each R 5 is independently F, Cl, -CN, C 1-3 alkyl, C 1 - 2 fluoroalkyl, or -OCH 3 ; each R x is independently H or -CH 3 ; each R y is independently H or C 1-6 alkyl; m is zero, 1, 2, 3, or 4; n is zero, 1, 2, 3, or 4; each p is independently zero, 1, 2, 3, or 4; x is zero, 1, or 2; and y is zero, 1, or 2. <EOS>