mhurhangee/patent-ind-claim-en huggingface dataset:
A hollow fiber filtration membrane for removing impurities from protein solutions, said hollow fiber filtration membrane comprising a polysulfone-based polymer and a hydrophilic polymer and having a large number of pores, wherein the hollow fiber filtration membrane has a gradient asymmetric porous structure in which an average pore diameter of the pores increases from an outer surface portion toward an inner surface portion of the membrane, a content of the hydrophilic polymer of the membrane is from 6.0 to 10.0% by mass, and a ratio between a content of the hydrophilic polymer at the inner surface portion and the content of the hydrophilic polymer of the membrane is in the range of from 0.50 to 0.80, wherein the content of the hydrophilic polymer in the membrane and the ratio between the content of hydrophilic polymer at the inner surface portion and the content of the hydrophilic polymer of the membrane is determined as described in the description.
A coating composition comprising (A) organosiloxane obtainable from hydrosilylation reaction of organohydrogensiloxane having at least two hydrosilyl groups per molecule with alkenyl-containing alkoxysilane having the general formula : wherein m is an integer of 4 to 6, n is 0, 1 or 2, R 1 and R 2 are each independently C 1 -C 3 alkyl or C 6 -C 10 aryl, and (B) an organometallic catalyst. (A) organosiloxane obtainable from hydrosilylation reaction of organohydrogensiloxane having at least two hydrosilyl groups per molecule with alkenyl-containing alkoxysilane having the general formula : wherein m is an integer of 4 to 6, n is 0, 1 or 2, R 1 and R 2 are each independently C 1 -C 3 alkyl or C 6 -C 10 aryl, and (B) an organometallic catalyst.
An intermittent urinary catheter assembly comprising: - an intermittent urinary catheter comprising a catheter tube with a proximal insertion end and a distal outlet end , the catheter tube comprising at least two draining openings at a proximal portion, - a handle connected to the distal outlet end of the catheter tube, the handle comprising a first cavity and a second cavity , the first cavity being adapted to provide a through-going hole for draining liquid, and characterised in that the assembly further comprises - a protective tube adapted for being telescoped in a longitudinal direction between a first proximal position and a second distal position, wherein, in the first proximal position, the protective tube at least partly covers the catheter tube , and, in the second distal position, the protective tube is positioned in the second cavity of the handle thereby exposing the full length of the catheter tube for insertion. - an intermittent urinary catheter comprising a catheter tube with a proximal insertion end and a distal outlet end , the catheter tube comprising at least two draining openings at a proximal portion, - a handle connected to the distal outlet end of the catheter tube, the handle comprising a first cavity and a second cavity , the first cavity being adapted to provide a through-going hole for draining liquid, and characterised in that the assembly further comprises - a protective tube adapted for being telescoped in a longitudinal direction between a first proximal position and a second distal position, wherein, in the first proximal position, the protective tube at least partly covers the catheter tube , and, in the second distal position, the protective tube is positioned in the second cavity of the handle thereby exposing the full length of the catheter tube for insertion.
An in vitro method for diagnosis of NASH, Non-alcoholic steato-hepatitis, in a patient comprising the step of: a) combining the values as measured from markers present in the serum or plasma of said patient through a logistic function, so as to obtain an index, wherein said index is to be compared to a reference index, wherein said first logistic function is a1 + a2 x Log (alpha2-macroglobulin (A2M), g/l) + a3 x Age (years) + a4 x Log (alanine aminotransferase (ALT), IU / l) + a5 x (apolipoprotein A-1 (Apoa1), g/l) + a6 x Log (Aspartate transaminase (AST), IU/l) + a7 x Log (total bilirubin (BILl), μmol/l) + a8 x Log (cholesterol (CT), mmol/l) + a9 x Gender (0 for women, 1 for men) + a10 x Log(gamma-glutamyl transpeptidase (GGT), IU / l) + a11 x Log (Haptoglobin (Hapto), g/l) + a12 x Log (Triglycerides (TG), mmol/l) wherein i. − 8 ≤ a 1 ≤ − 7 ii. 0.1 ≤ a2 ≤ 0.6 preferably 0.15 ≤ a2 ≤ 0.55 iii. 0.02 ≤ a3 ≤ 0.05 preferably 0.03 ≤ a3 ≤ 0.04 iv. 1.1 ≤ a4 ≤ 1.5 preferably 1.2 ≤ a4 ≤ 1.4 v. − 0.2 ≤ a 5 ≤ 1.0 vi. 1.8 ≤ a6 ≤ 2.3 preferably 1.95 ≤ a6 ≤ 2.2 vii. 0.8 ≤ a7 ≤ 1.6 preferably 0.9 ≤ a7 ≤ 1.5 viii. -1.7 ≤ a8 ≤ -1.3 preferably -1.6 ≤ a8 ≤ -1.4 ix. 0.015 ≤ a9 ≤ 0.20 x. 0.15 ≤ a10 ≤ 0.25 preferably 0.20 ≤ a10 ≤ 0.22 xi. − 0.3 ≤ a 11 ≤ 0.1 xii. 0.9 ≤ a12 ≤ 1.2 preferably 1.0 ≤ a12 ≤ 1.1. a) combining the values as measured from markers present in the serum or plasma of said patient through a logistic function, so as to obtain an index, wherein said index is to be compared to a reference index, wherein said first logistic function is a1 + a2 x Log (alpha2-macroglobulin (A2M), g/l) + a3 x Age (years) + a4 x Log (alanine aminotransferase (ALT), IU / l) + a5 x (apolipoprotein A-1 (Apoa1), g/l) + a6 x Log (Aspartate transaminase (AST), IU/l) + a7 x Log (total bilirubin (BILl), μmol/l) + a8 x Log (cholesterol (CT), mmol/l) + a9 x Gender (0 for women, 1 for men) + a10 x Log(gamma-glutamyl transpeptidase (GGT), IU / l) + a11 x Log (Haptoglobin (Hapto), g/l) + a12 x Log (Triglycerides (TG), mmol/l) wherein i. − 8 ≤ a 1 ≤ − 7 ii. 0.1 ≤ a2 ≤ 0.6 preferably 0.15 ≤ a2 ≤ 0.55 iii. 0.02 ≤ a3 ≤ 0.05 preferably 0.03 ≤ a3 ≤ 0.04 iv. 1.1 ≤ a4 ≤ 1.5 preferably 1.2 ≤ a4 ≤ 1.4 v. − 0.2 ≤ a 5 ≤ 1.0 vi. 1.8 ≤ a6 ≤ 2.3 preferably 1.95 ≤ a6 ≤ 2.2 vii. 0.8 ≤ a7 ≤ 1.6 preferably 0.9 ≤ a7 ≤ 1.5 viii. -1.7 ≤ a8 ≤ -1.3 preferably -1.6 ≤ a8 ≤ -1.4 ix. 0.015 ≤ a9 ≤ 0.20 x. 0.15 ≤ a10 ≤ 0.25 preferably 0.20 ≤ a10 ≤ 0.22 xi. − 0.3 ≤ a 11 ≤ 0.1 xii. 0.9 ≤ a12 ≤ 1.2 preferably 1.0 ≤ a12 ≤ 1.1. i. − 8 ≤ a 1 ≤ − 7 ii. 0.1 ≤ a2 ≤ 0.6 preferably 0.15 ≤ a2 ≤ 0.55 iii. 0.02 ≤ a3 ≤ 0.05 preferably 0.03 ≤ a3 ≤ 0.04 iv. 1.1 ≤ a4 ≤ 1.5 preferably 1.2 ≤ a4 ≤ 1.4 v. − 0.2 ≤ a 5 ≤ 1.0 vi. 1.8 ≤ a6 ≤ 2.3 preferably 1.95 ≤ a6 ≤ 2.2 vii. 0.8 ≤ a7 ≤ 1.6 preferably 0.9 ≤ a7 ≤ 1.5 viii. -1.7 ≤ a8 ≤ -1.3 preferably -1.6 ≤ a8 ≤ -1.4 ix. 0.015 ≤ a9 ≤ 0.20 x. 0.15 ≤ a10 ≤ 0.25 preferably 0.20 ≤ a10 ≤ 0.22 xi. − 0.3 ≤ a 11 ≤ 0.1 xii. 0.9 ≤ a12 ≤ 1.2 preferably 1.0 ≤ a12 ≤ 1.1.
A medical apparatus for performing ablation, comprising: a probe configured for insertion into a body of a patient and comprising three or more electrodes arrayed along a distal portion of the probe and configured to contact tissue within the body; an electrical signal generator configured to apply, between a selected pair of the electrodes, signals having an amplitude sufficient to ablate the tissue contacted by the pair of the electrodes; and a controller , which is configured to measure an electrical current flowing through at least one of the electrodes not included in the selected pair while applying the signals, and to issue a notification indicating that the tissue was inadequately ablated if the measured electrical current exceeds a preset threshold. a probe configured for insertion into a body of a patient and comprising three or more electrodes arrayed along a distal portion of the probe and configured to contact tissue within the body; an electrical signal generator configured to apply, between a selected pair of the electrodes, signals having an amplitude sufficient to ablate the tissue contacted by the pair of the electrodes; and a controller , which is configured to measure an electrical current flowing through at least one of the electrodes not included in the selected pair while applying the signals, and to issue a notification indicating that the tissue was inadequately ablated if the measured electrical current exceeds a preset threshold.
A plant control supporting apparatus comprising: a segment selector configured to select, from among a plurality of segments defined in a plant , a segment for which learning for acquiring an optimal value of at least one parameter representing an operation state is executed; a reward function definer configured to define a reward function used for the learning; a parameter extractor configured to extract at least one parameter that is a target for the learning in the selected segment on the basis of input and output diagram of a device used in the plant and segment information representing a configuration of a device included in the selected segment; and a learner configured to perform the learning for acquiring the optimal value of the at least one parameter for each segment on the basis of the reward function and the extracted at least one parameter; wherein the segment selector is configured to sequentially select the plurality of segments defined in the plant in accordance with a flow of processes in the plant . a segment selector configured to select, from among a plurality of segments defined in a plant , a segment for which learning for acquiring an optimal value of at least one parameter representing an operation state is executed; a reward function definer configured to define a reward function used for the learning; a parameter extractor configured to extract at least one parameter that is a target for the learning in the selected segment on the basis of input and output diagram of a device used in the plant and segment information representing a configuration of a device included in the selected segment; and a learner configured to perform the learning for acquiring the optimal value of the at least one parameter for each segment on the basis of the reward function and the extracted at least one parameter; wherein the segment selector is configured to sequentially select the plurality of segments defined in the plant in accordance with a flow of processes in the plant .
Drug delivery device for selecting and dispensing a number of user variable doses of a medicament, the device comprising a housing , a dose selector operable to set a dose by rotation relative to the housing , a number sleeve arranged within the housing such that at least a portion of the number sleeve is visible through a first aperture in the housing , and a piston rod coupled to the housing and to a drive sleeve such that rotation of the drive sleeve relative to the housing causes the piston rod to translate relative to the housing , characterized in that the piston rod is rotationally constrained to the drive sleeve via a splined interface and is coupled to the housing via a threaded interface with at least two different pitches, such that the piston rod is translated a larger amount relative to the housing during the first revolution of the drive sleeve relative to the housing than during the subsequent revolutions, wherein the threaded interface comprises a first threaded portion on the piston rod having a larger pitch compared with a second threaded portion on the piston rod such that the axial displacement of the piston rod upon rotation relative to the housing is larger when the thread of the housing engages the first threaded portion compared with the axial displacement of the piston rod upon rotation relative to the housing when the thread of the housing engages the second threaded portion.
A piston type pump , comprising: a pump housing having at least one pump inlet and one pump outlet and a piston arrangement connected to a driving shaft which, when driven, sets the piston arrangement into movement, wherein the piston arrangement comprises: a first primary stage piston , the first primary stage piston being slidably seated in a first primary stage cylinder formed in the pump housing ; a first secondary stage piston ; wherein the first secondary stage piston being slidably seated in a first secondary stage cylinder formed in the first primary stage piston , wherein the piston arrangement further comprises a second primary stage piston , whereas the second primary stage piston being slidably seated in a second primary stage cylinder formed in the pump housing ; and a second secondary stage piston , the second secondary stage piston being slidably seated in a second secondary stage cylinder formed in the second primary stage piston , characterized in that the first secondary stage piston is attached to the second primary stage piston ; and the second secondary stage piston is attached to the first primary stage piston . a first primary stage piston , the first primary stage piston being slidably seated in a first primary stage cylinder formed in the pump housing ; a first secondary stage piston ; a second primary stage piston , whereas the second primary stage piston being slidably seated in a second primary stage cylinder formed in the pump housing ; and a second secondary stage piston , the second secondary stage piston being slidably seated in a second secondary stage cylinder formed in the second primary stage piston , characterized in that the first secondary stage piston is attached to the second primary stage piston ; and the second secondary stage piston is attached to the first primary stage piston .
An organic light emitting display device comprising: an organic light emitting element layer in an active area (A/A); and a multi-layer face seal structure covering the organic light emitting element layer , the multi-layer face seal structure comprising one or more inorganic films (121-1, 121-2) and one or more organic films , wherein the one or more inorganic films (121-1, 121-2) and the one or more organic films covering the entire active area (A/A) and a part of an inactive area (I/A) surrounding the active area (A/A), and the one or more inorganic films (121-1, 121-2) are disposed only at a portion having a predetermined inward distance from an outermost periphery of the inactive area (I/A), characterized in that the one or more inorganic films (121-1, 121-2) have a chamfered shape at one or more corners of the organic light emitting display device (100-1, 100-2, 100-3, 100-4), such that, when viewed in a plan view, a square shape portion is cut at at least one of the corners between two adjoining sides of the one or more inorganic films (121-1, 121-2) forming a right angle, or a slope cut is formed at at least one of the corners between two adjoining sides of the one or more inorganic films (121-1, 121-2) forming a right angle, or a stepped shape is formed at at least one of the corners between two adjoining sides of the one or more inorganic films (121-1, 121-2) forming a right angle. an organic light emitting element layer in an active area (A/A); and a multi-layer face seal structure covering the organic light emitting element layer , the multi-layer face seal structure comprising one or more inorganic films (121-1, 121-2) and one or more organic films , wherein the one or more inorganic films (121-1, 121-2) and the one or more organic films covering the entire active area (A/A) and a part of an inactive area (I/A) surrounding the active area (A/A), and the one or more inorganic films (121-1, 121-2) are disposed only at a portion having a predetermined inward distance from an outermost periphery of the inactive area (I/A), characterized in that the one or more inorganic films (121-1, 121-2) have a chamfered shape at one or more corners of the organic light emitting display device (100-1, 100-2, 100-3, 100-4), such that, when viewed in a plan view, a square shape portion is cut at at least one of the corners between two adjoining sides of the one or more inorganic films (121-1, 121-2) forming a right angle, or a slope cut is formed at at least one of the corners between two adjoining sides of the one or more inorganic films (121-1, 121-2) forming a right angle, or a stepped shape is formed at at least one of the corners between two adjoining sides of the one or more inorganic films (121-1, 121-2) forming a right angle.
An adhesive composition comprising an antistatic agent that includes an ionic compound having a melting point of not less than 50°C, and a base polymer having a glass transition temperature Tg of not more than 0°C, wherein the base polymer is an acryl polymer including at least one selected from acrylate and/or methacrylate, which have 1 to 14 carbon atoms in an alkyl group, in an amount of 50% by weight ("wt.%") to 100wt, wherein the base polymer is cross-linked by cross-linking agent, and the cross-linking agent is combined with the base polymer in an amount ranging from 0.01 to 5wt. parts to 100wt. parts of the base polymer, wherein the antistatic agent is added in an amount ranging from 0.01 to 1.8wt.% relative to total weight of the base polymer and the antistatic agent, and wherein the base polymer contained in the adhesive composition has a cross-linking degree ranging from 50 to 80% in terms of gel fraction rate; wherein the ionic compound is at least one selected from a group consisting of imidazolium salts, pyridinium salts, alkylammonium salts, alkylpyrrolidium salts and alkylphosphonium salts, wherein the pyridinium salts are 1-butyl-3-methylpyridinium bromide, 1-butyl-4-methylpyridinium bromide, 1-butyl-4-methylpyridinium chloride; 1-butylpyridinium bromide, 1-butylpyridinium chloride, 1-butylpyridinium hexafluorophosphate, 1-ethylpyridinium bromide or 1-ethylpyridinium chloride, wherein the alkylammonium salts are cyclohexyltrimethylammonium bis(trifluoromethanesulfonyl)imide, tetra-n-butylammonium chloride, tetrabutylammonium bromide, tributylmethylammonium methylsulfate, tetrabutylammonium bis(trifluoromethylsulfonyl)imide, tetraethylammonium trifluoromethanesulfonate, tetrabutylammonium benzoate, tetrabutylammonium methanesulfate, tetrabutylammonium nonafluorobutanesulfonate, tetrabutylammonium trifluoroacetate, tetrahexylammonium tetrafluoroborate, tetrahexylammonium bromide, tetrahexylammonium iodide, tetraoctylammonium chloride, tetraoctylammonium bromide, tetraheptylammonium bromide, tetrapentylammonium bromide or n-hexadecyltrimethylammonium hexafluorophosphate. and wherein Tg and gel-fraction are measured using the methods described in this specification.
A heating element for a vaporization device , wherein the heating element comprises: a conductive layer , configured to be disposed on a substrate , wherein the heating element is configured to have an effective surface area for fluid vaporization that is greater than a planar surface area defined by dimensions of the heating element ; a protective layer , configured to be disposed on the conductive layer and the protective layer is made of a high temperature material that is substantially non-porous; and a porous layer , configured to be disposed on the protective layer and having a porosity of at least about 50%. a conductive layer , configured to be disposed on a substrate , wherein the heating element is configured to have an effective surface area for fluid vaporization that is greater than a planar surface area defined by dimensions of the heating element ; a protective layer , configured to be disposed on the conductive layer and the
Timepiece movement comprising a power source , a finishing going train , an escapement connected to the power source by the finishing going train , a resonator cooperating with the escapement , a driven mobile , a coupling lever and a coupling wheel controlled by the coupling lever in order, with the coupling lever in a coupled position, to mesh with the driven mobile in order to transmit the rotation of the finishing going train to the driven mobile and, with the coupling lever in a decoupled position, to be out of contact with the driven mobile , characterised in that the coupling wheel forms part of a mobile of the finishing going train .
Nanoparticles formed by emulsion of one or more core polymers, one or more surface altering materials, and one or more low molecular weight emulsifiers having a molecular weight less than 1500 amu, wherein the one or more surface altering materials are selected from the group consisting of polyethylene glycol (PEG) and poloxamer, or wherein the particles are formed from block copolymers containing PEG, wherein the nanoparticle possess a ζ-potential of between 10 mV and -10 mV when dispersed in 10 mM NaCl solution at pH 7; wherein the nanoparticles further comprise one or more therapeutic, prophylactic, or diagnostic agents, and wherein the nanoparticles penetrate cervicovaginal mucus (CVM) with effective speeds less than 25-fold slower than the same particles in water. wherein the one or more surface altering materials are selected from the group consisting of polyethylene glycol (PEG) and poloxamer, or wherein the particles are formed from block copolymers containing PEG, wherein the nanoparticle possess a ζ-potential of between 10 mV and -10 mV when dispersed in 10 mM NaCl solution at pH 7; wherein the nanoparticles further comprise one or more therapeutic, prophylactic, or diagnostic agents, and wherein the nanoparticles penetrate cervicovaginal mucus (CVM) with effective speeds less than 25-fold slower than the same particles in water.
A method of recycling film-to-film laminates, the film-to film laminates having a first polymeric film and at least one second polymeric or metal film, the first and second films are bonded to one another using a laminating adhesive, the method comprising detaching the first from the second film by treating the film-to-film laminate with an aqueous liquid with a pH of greater 8 at a temperature of 40 °C or more, wherein the first and the second films are bonded to one another with the laminating adhesive so firmly that the peel strength, measured 24 h after laminate production and at 23°C and 50% relative humidity, at an angle of 90° and a removal velocity of 100 mm/min, is 1 N/15 mm or more, and wherein the adhesive polymer of the laminating adhesive has a glass transition temperature of -30 to +15°C measured by Differential Scanning Calorimetry according to ASTM D 3418-08 as the midpoint temperature of the second heating curve at a heating rate of 20°C/min, characterized in that the surface energy of a film of the laminating adhesive is more than 30 mN/m if the water vapor transmission rate of each of the first and second films is less than or equal 10 g/m 2 d, and the surface energy of a film of the laminating adhesive is more than 19 mN/m if the water vapor transmission rate of at least one of the first and second films is more than 10 g/m 2 d, water vapor transmission rate is measured for 25 μm films at 38 °C and 90% relative humidity; and surface energy is measured as free surface energy as described in the examples. the method comprising detaching the first from the second film by treating the film-to-film laminate with an aqueous liquid with a pH of greater 8 at a temperature of 40 °C or more, wherein the first and the second films are bonded to one another with the laminating adhesive so firmly that the peel strength, measured 24 h after laminate production and at 23°C and 50% relative humidity, at an angle of 90° and a removal velocity of 100 mm/min, is 1 N/15 mm or more, and wherein the adhesive polymer of the laminating adhesive has a glass transition temperature of -30 to +15°C measured by Differential Scanning Calorimetry according to ASTM D 3418-08 as the midpoint temperature of the second heating curve at a heating rate of 20°C/min, characterized in that the surface energy of a film of the laminating adhesive is more than 30 mN/m if the water vapor transmission rate of each of the first and second films is less than or equal 10 g/m 2 d, and the surface energy of a film of the laminating adhesive is more than 19 mN/m if the water vapor transmission rate of at least one of the first and second films is more than 10 g/m 2 d, water vapor transmission rate is measured for 25 μm films at 38 °C and 90% relative humidity; and surface energy is measured as free surface energy as described in the examples.