A method for managing the power supply in an electronic circuit comprising a processing system (11; 11'), in particular a general purpose microcontroller or a System-on-Chip or a subsystem thereof, with a radio-frequency embedded circuit , said processing system (11; 11') comprising at least a processing core (30, V12I, V12O) and a first power regulation module supplying a first regulated voltage (V12) to said processing core , said radio frequency embedded circuit comprising a second power regulation module supplying a second regulated voltage (V reg ) to circuits of the radio-frequency embedded circuit including a radio frequency transceiving portion , said second power regulation module comprising a switched-mode power supply and generating a second regulated voltage (V reg ), said method comprising coupling said second regulated voltage (V reg ) as voltage input of said first power regulation module , said first power regulation module which generates as an output a respective first regulated voltage (V regm ) for said processing core , controlling said second power regulation module to operate according to a plurality of operation modes (LP1, LP2, A1, A2, LP3, LP4) including one or more sleep modes (LP1, LP2) in which both the DC-DC converter and the second linear regulator are off and one or more active modes (A1, A2) in which both the DC-DC converter and the second linear regulator are on, wherein said second power regulation module comprises a second linear regulator and said plurality of modes (LP1, LP2, A1, A2, LP3, LP4) includes a first further sleep mode (LP3) in which the switched-mode power supply is off and the second linear regulator is on and a second further sleep mode in which the switched-mode power supply is on and the second linear regulator is off, the first further sleep mode (LP3) and second further sleep mode (LP4) being controlled by the processing system . said processing system (11; 11') comprising at least a processing core (30, V12I, V12O) and a first power regulation module supplying a first regulated voltage (V12) to said processing core , said radio frequency embedded circuit comprising a second power regulation module supplying a second regulated voltage (V reg ) to circuits of the radio-frequency embedded circuit including a radio frequency transceiving portion , said second power regulation module comprising a switched-mode power supply and generating a second regulated voltage (V reg ), said method comprising coupling said second regulated voltage (V reg ) as voltage input of said first power regulation module , said first power regulation module which generates as an output a respective first regulated voltage (V regm ) for said processing core , controlling said second power regulation module to operate according to a plurality of operation modes (LP1, LP2, A1, A2, LP3, LP4) including one or more sleep modes (LP1, LP2) in which both the DC-DC converter and the second linear regulator are off and one or more active modes (A1, A2) in which both the DC-DC converter and the second linear regulator are on, wherein said second power regulation module comprises a second linear regulator and said plurality of modes (LP1, LP2, A1, A2, LP3, LP4) includes a first further sleep mode (LP3) in which the switched-mode power supply is off and the second linear regulator is on and a second further sleep mode in which the switched-mode power supply is on and the second linear regulator is off, the first further sleep mode (LP3) and second further sleep mode (LP4) being controlled by the processing system . <EOS>