A system for treating a tissue site , comprising: a dressing assembly , comprising: a dressing bolster having a first side and a second side , a comfort layer coupled to the second side of the dressing bolster , a sealing member comprising: a first sealing member covering the first side of the dressing bolster , and a second sealing member covering a portion of the second side of the dressing bolster and extending outward from the dressing bolster , wherein a portion of the first sealing member is coupled to the second sealing member , and a sealing ring positioned at the second side of the dressing bolster , wherein the first sealing member , the second sealing member , and the sealing ring are configured to provide a sealed space at the tissue site ; an access portal coupled to an exterior surface of the sealing member , wherein the access portal is configurable between an open state and a closed state, wherein the access portal provides a passage into the sealed space in the open state and a fluid seal in the closed state; and a reduced-pressure subsystem comprising a reduced-pressure source configured to be coupled in fluid communication with the sealed space. a dressing assembly , comprising: a dressing bolster having a first side and a second side , a comfort layer coupled to the second side of the dressing bolster , a sealing member comprising: a first sealing member covering the first side of the dressing bolster , and a second sealing member covering a portion of the second side of the dressing bolster and extending outward from the dressing bolster , wherein a portion of the first sealing member is coupled to the second sealing member , and a sealing ring positioned at the second side of the dressing bolster , wherein the first sealing member , the second sealing member , and the sealing ring are configured to provide a sealed space at the tissue site ; a dressing bolster having a first side and a second side , a comfort layer coupled to the second side of the dressing bolster , a sealing member comprising: a first sealing member covering the first side of the dressing bolster , and a second sealing member covering a portion of the second side of the dressing bolster and extending outward from the dressing bolster , wherein a portion of the first sealing member is coupled to the second sealing member , and a first sealing member covering the first side of the dressing bolster , and a second sealing member covering a portion of the second side of the dressing bolster and extending outward from the dressing bolster , wherein a portion of the first sealing member is coupled to the second sealing member , and a sealing ring positioned at the second side of the dressing bolster , wherein the first sealing member , the second sealing member , and the sealing ring are configured to provide a sealed space at the tissue site ; an access portal coupled to an exterior surface of the sealing member , wherein the access portal is configurable between an open state and a closed state, wherein the access portal provides a passage into the sealed space in the open state and a fluid seal in the closed state; and a reduced-pressure subsystem comprising a reduced-pressure source configured to be coupled in fluid communication with the sealed space. <EOS>