mhurhangee/patent-ind-claim-en huggingface dataset:
A pharmaceutical composition, comprising an isolated effector protein of a type III secretion system (T3SS)-containing bacterium of the genus Salmonella or Shigella or a fragment thereof, linked to a cargo molecule selected from the group consisting of nucleic acids, polypeptides, organic molecules, small organic molecules, metals, nanoparticles, viruses, modified viruses, viral vectors, antibodies and/or plasmids , for use in a method of treatment, wherein the effector protein or fragment is characterized in that it has an amino acid sequence at least 80% identical to SEQ ID NOs 1-9, 19-27, 37-65 or 550; and a) is recombinantly produced or chemically synthesized, b) optionally comprises at least one Leucin-rich repeat, and c) is a cell-penetrating protein, which translocates into eukaryotic cells without the requirement of a bacterial T3SS; and wherein SEQ ID NOs 1-9 and 19-27 additionally comprise an E3 ubiquitin ligase domain; and wherein the pharmaceutical composition comprises no bacterial T3SS and the effector protein delivers the cargo molecule across the membrane of a eukaryotic cell without the requirement of the bacterial T3SS. a) is recombinantly produced or chemically synthesized, b) optionally comprises at least one Leucin-rich repeat, and c) is a cell-penetrating protein, which translocates into eukaryotic cells without the requirement of a bacterial T3SS; and wherein SEQ ID NOs 1-9 and 19-27 additionally comprise an E3 ubiquitin ligase domain; and
A method for producing an optical waveguide; said method comprising steps of: (a) depositing on a substrate a first composition comprising: (i) a first polysiloxane comprising epoxy groups and alkenyl groups, (ii) a first silane crosslinker comprising at least two silicon-hydrogen bonds, (iii) at least one first compound comprising an epoxy group, having molecular weight no greater than 1000 10 -3 kg/mol and a refractive index at least 0.002 higher than a weight average refractive index of the first polysiloxane and the first silane crosslinker, (iv) at least one hydrosilylation catalyst, (v) at least one inhibitor for hydrosilylation, and (vi) at least one photo acid generator; (b) heating to produce a cured first composition; (c) depositing on the cured first composition a second composition comprising: (i) a second polysiloxane comprising epoxy groups and alkenyl groups, (ii) a second silane crosslinker comprising at least two silicon-hydrogen bonds, (iii) at least one hydrosilylation catalyst, and (iv) at least one inhibitor for hydrosilylation, to produce a composite; (d) curing the second composition by heating to produce a composite; (e) exposing the composite to ultraviolet light through a mask to produce a patterned core layer comprising a cured portion of the first composition and an uncured portion of the first composition; and (f) heating to evaporate at least a part of the uncured portion of the first composition to produce a final patterned core layer. (a) depositing on a substrate a first composition comprising: (i) a first polysiloxane comprising epoxy groups and alkenyl groups, (ii) a first silane crosslinker comprising at least two silicon-hydrogen bonds, (iii) at least one first compound comprising an epoxy group, having molecular weight no greater than 1000 10 -3 kg/mol and a refractive index at least 0.002 higher than a weight average refractive index of the first polysiloxane and the first silane crosslinker, (iv) at least one hydrosilylation catalyst, (v) at least one inhibitor for hydrosilylation, and (vi) at least one photo acid generator; (b) heating to produce a cured first composition; (c) depositing on the cured first composition a second composition comprising: (i) a second polysiloxane comprising epoxy groups and alkenyl groups, (ii) a second silane crosslinker comprising at least two silicon-hydrogen bonds, (iii) at least one hydrosilylation catalyst, and (iv) at least one inhibitor for hydrosilylation, to produce a composite; (d) curing the second composition by heating to produce a composite; (e) exposing the composite to ultraviolet light through a mask to produce a patterned core layer comprising a cured portion of the first composition and an uncured portion of the first composition; and (f) heating to evaporate at least a part of the uncured portion of the first composition to produce a final patterned core layer.
Method for reducing an energy demand of a machine tool of a machine tool system , wherein the machine tool system comprises at least a first machine tool having a first machine cycle time and a second machine tool having a second machine cycle time, wherein identical workpieces are initially supplied to the first machine tool and then to the second machine tool in chronological order in order to be machined and wherein the second machine cycle time is shorter than the first machine cycle time, characterized in that the workpieces are collected after machining by the first machine tool before being supplied to the second machine tool , wherein a specified number of workpieces are collected after machining by the first machine tool .
A device comprising: - equipment configured for extracting first preliminary timing information from a first circular polarized component of a radio signal and for extracting second preliminary timing information from a second circular polarized component of the radio signal, the second circular polarized component of the radio signal having an opposite handedness and a time-delay with respect to the first circular polarized component of the radio signal, and - a processing system configured for producing timing information based on at least one of the following: the first preliminary timing information and the second preliminary timing information, wherein the processing system is configured to use stored correction data for reducing an effect of the time-delay on the timing information when producing the timing information based on at least the second preliminary timing information, characterized in that the processing system is configured to monitor a power level of the first circular polarized component of the radio signal, measure the time-delay on the basis of the second preliminary timing information and the first preliminary timing information when monitoring the power level, and form and store the correction data based on the measured time-delay at each time when the monitored power level exceeds a power level corresponding to previously stored correction data. - equipment configured for extracting first preliminary timing information from a first circular polarized component of a radio signal and for extracting second preliminary timing information from a second circular polarized component of the radio signal, the second circular polarized component of the radio signal having an opposite handedness and a time-delay with respect to the first circular polarized component of the radio signal, and - a processing system configured for producing timing information based on at least one of the following: the first preliminary timing information and the second preliminary timing information, wherein the processing system is configured to use stored correction data for reducing an effect of the time-delay on the timing information when producing the timing information based on at least the second preliminary timing information,
A coalescing filter for water/oil disperse system separation comprising a chamber with an inlet, an outlet and a chamber cavity filled with at least one coalescing medium , wherein the coalescing medium comprises a product of mechanical machining of synthetic cord-based rubber products into flow spiral chips and/or flow strip-shaped chips having longitudinal surface roughness with medium size in the range of 0.1 to 20 μm, through-perforation of the surface, thickness in the range of 0.05 mm to 5 mm, width in the range of 0.05 mm to 20 mm and length at least 100 mm, wherein said mechanical machining are selected from the group comprising lathe turning, drilling, shaping and milling, and said synthetic cord-based rubber products are selected from the group comprising worn motor tires, tire casings, conveyor belts, scrap rubber hoses and driving belts.
Method of removing a liquid adhering to a convex bottom of a container for accommodating an ophthalmic lens, in particular a contact lens such as a soft contact lens, during transporting the container , which enables the flow of liquid into and out of the container , from a liquid bath to a subsequent processing station , the method comprising the steps of: - transporting the container from the liquid bath to the subsequent processing station , - providing an aspirator comprising a suction cup having a concave wall with at least one suction orifice arranged in the concave wall , the concave wall of the suction cup having a shape which corresponds to the shape of the convex bottom of the container, - generating suction , - applying the suction through the at least one suction orifice arranged in the concave wall of the suction cup , - moving the suction cup towards the convex bottom of the container with the concave wall of the suction cup facing the convex bottom of the container , applying the suction to the convex bottom of the container during the step of transporting the container from the liquid bath to the subsequent processing station, thereby removing from the container the liquid adhering to the convex bottom of the container, - wherein the suction cup is moved towards the convex bottom of the container only to an extent that the suction cup does not contact the convex bottom of the container , and - wherein applying the suction to the convex bottom of the container allows a leakage stream to flow between the bottom of the container and the concave wall of the suction cup towards the at least one suction orifice in the concave wall of the suction cup . - transporting the container from the liquid bath to the subsequent processing station , - providing an aspirator comprising a suction cup having a concave wall with at least one suction orifice arranged in the concave wall , the concave wall of the suction cup having a shape which corresponds to the shape of the convex bottom of the container, - generating suction , - applying the suction through the at least one suction orifice arranged in the concave wall of the suction cup , - moving the suction cup towards the convex bottom of the container with the concave wall of the suction cup facing the convex bottom of the container , applying the suction to the convex bottom of the container during the step of transporting the container from the liquid bath to the subsequent processing station, thereby removing from the container the liquid adhering to the convex bottom of the container, - wherein the suction cup is moved towards the convex bottom of the container only to an extent that the suction cup does not contact the convex bottom of the container , and - wherein applying the suction to the convex bottom of the container allows a leakage stream to flow between the bottom of the container and the concave wall of the suction cup towards the at least one suction orifice in the concave wall of the suction cup .
A cylinder block for an internal combustion engine, comprising: a bore having an iron-based sprayed coating for coating a bore inner surface of a cylinder block for an internal combustion engine, wherein the cylinder block body is made from aluminum alloy, wherein a surface of the coating contains pits, and the amount of the pits is within a range of 0.01% to 2.1%, wherein the amount of pits means a total sum (percentage) of an area occupied by all the pits present in a unit coating surface area when observing the sprayed coating by plane observation; an average roughness Ra of the coating surface is within a range of 0.01 μm to 0.15 μm; the iron-based sprayed coating has pores, and whose cross section porosity is within a range of 0.01% to 2.1%, wherein the cross-section porosity means a total sum (percentage) of an area occupied by all the pores present in the unit cross-section area when observing the sprayed coating as a cross-section; an average hardness of the iron-based sprayed coating is within a range of HV280 to HV500; and the iron-based sprayed coating, comprises: iron as its main component; and carbon in an amount of 0.05 mass% to 0.25 mass%, on an inner surface thereof; and a cylinder block body having said bore.
An acupuncture needle , comprising: a needle body having a needle tip portion formed at a leading end thereof; and a needle grip attached to a base end portion of the needle body , wherein a cross-sectional shape of the needle grip crossing a longitudinal direction perpendicularly is an ellipse, the needle tip portion has a pointed shape and not a hook-shape, the needle body is in a linear shape without being curved in a middle thereof, and the needle body is not removable from the needle grip , wherein among straight lines crossing an outer peripheral edge of a cross section crossing the longitudinal direction of the needle grip perpendicularly, a first long diameter being a major axis (A; A') of the ellipse and having a length longest between one portion of an outer peripheral edge and another portion of the outer peripheral edge, and among straight lines orthogonal to the first long diameter and crossing the outer peripheral edge of the cross section, a second long diameter being a minor axis (B; B') of the ellipse having a length longest between one portion of the outer peripheral edge and another portion of the outer peripheral edge, wherein the first long diameter and the second long diameter are in a relation such that the length of the first long diameter is greater than the length of the second long diameter . a needle body having a needle tip portion formed at a leading end thereof; and a needle grip attached to a base end portion of the needle body , wherein a cross-sectional shape of the needle grip crossing a longitudinal direction perpendicularly is an ellipse, the needle tip portion has a pointed shape and not a hook-shape, the needle body is in a linear shape without being curved in a middle thereof, and the needle body is not removable from the needle grip , wherein among straight lines crossing an outer peripheral edge of a cross section crossing the longitudinal direction of the needle grip perpendicularly, a first long diameter being a major axis (A; A') of the ellipse and having a length longest between one portion of an outer peripheral edge and another portion of the outer peripheral edge, and among straight lines orthogonal to the first long diameter and crossing the outer peripheral edge of the cross section, a second long diameter being a minor axis (B; B') of the ellipse having a length longest between one portion of the outer peripheral edge and another portion of the outer peripheral edge, wherein the first long diameter and the second long diameter are in a relation such that the length of the first long diameter is greater than the length of the second long diameter .
Method for operating a pulsed laser system, comprising the steps of: - pumping a laser resonator with a laser rod of the pulsed laser system by means of a pump source in order to generate operating laser pulses at an operating energy level (LO) , wherein the operating energy level is in a range from 100 mJ to 3000 mJ suitable to treat a target area; - coupling the operating laser pulses with a focusing element into an optical fiber , and wherein a laser beam of the operating laser pulses and cleaning laser pulses is coupled into a proximal end face of the optical fiber, - controlling the pump source with a control unit at an operating voltage and/or operating current such that pump energy is provided to the laser resonator at a high level for generating the operating laser pulses at an operating energy level, characterized by - a step of cleaning the optical fiber prior to generating the operating laser pulses by means of the cleaning laser pulses, wherein the control unit controls the pump source at one or more cleaning voltages and/or one or more cleaning currents such that pump energy is provided to the laser resonator at one or more low levels, wherein the laser resonator of the pulsed laser system is pumped by means of the pump source in order to generate the cleaning laser pulses at one or more cleaning energy levels between a laser threshold (LT) and the operating energy level (LO) , wherein the pump pulse duration for the cleaning laser pulses is at least 600 μs, and wherein at least part of a plurality of contaminations is removed from the proximal end face of the optical fiber. - pumping a laser resonator with a laser rod of the pulsed laser system by means of a pump source in order to generate operating laser pulses at an operating energy level (LO) , wherein the operating energy level is in a range from 100 mJ to 3000 mJ suitable to treat a target area; - coupling the operating laser pulses with a focusing element into an optical fiber , and wherein a laser beam of the operating laser pulses and cleaning laser pulses is coupled into a proximal end face of the optical fiber, - controlling the pump source with a control unit at an operating voltage and/or operating current such that pump energy is provided to the laser resonator at a high level for generating the operating laser pulses at an operating energy level, - a step of cleaning the optical fiber prior to generating the operating laser pulses by means of the cleaning laser pulses, wherein the control unit controls the pump source at one or more cleaning voltages and/or one or more cleaning currents such that pump energy is provided to the laser resonator at one or more low levels, wherein the laser resonator of the pulsed laser system is pumped by means of the pump source in order to generate the cleaning laser pulses at one or more cleaning energy levels between a laser threshold (LT) and the operating energy level (LO) , wherein the pump pulse duration for the cleaning laser pulses is at least 600 μs, and wherein at least part of a plurality of contaminations is removed from the proximal end face of the optical fiber.
A borosilicate glass, comprising the following constituents based on oxide: SiO 2 70-77 wt%, B 2 O 3 9.0-12 wt%, Al 2 O 3 3.0-7.0 wt%, Na 2 O 5.0-8.0 wt%, K 2 O 0-2.0 wt%, Li 2 O 0-1.0 wt%, wherein ∑ (Na 2 O + K 2 O + LizO) 5.0-9.0 wt%, CaO 0-3.0 wt%, MgO 0-1.0 wt%, BaO 0-2.0 wt%, wherein ∑ (CaO+ MgO+ BaO) 0-5.0 wt%, CeO 2 0-1.0 wt%, NaCl 0-1.0 wt%, Y 2 O 3 0.25-4.0 wt%.
Method for operating a machine tool having a battery and an electric motor which is designed to rotationally drive an output shaft that can be coupled to a tool , a control device for actuating the electric motor and a device for determining a parameter being provided, it being possible for the machine tool to be operated in a first operating mode and a second operating mode, and the machine tool being transferred from the first operating mode into the second operating mode if the parameter determined by the device exceeds or falls below a defined threshold value, the electric motor being controlled in the second operating mode by an amperage profile, the amperage profile comprising first current pulses and second current pulses , and the level of a maximum amperage (A1, A1') of the first current pulses being greater than the level of a maximum amperage (A2) of the second current pulses , characterized in that the electric motor is controlled in the second operating mode alternately by a first current pulse and then a plurality of second current pulses , in particular two to twenty, preferably five to fourteen, more preferably eight to ten second current pulses.
Method for operating an elevator system , in particular an elevator system operated by means of linear motors, wherein the elevator system comprises a shaft system comprising at least one vertical elevator shaft ; and a plurality of elevator cars , each comprising a plurality of functional components for carrying out different functions, wherein in a special operating mode of the elevator system at least one auxiliary device is associated to a first elevator car , wherein the at least one auxiliary device provides a substitute function for at least one function of one of the functional components of the first elevator car , wherein the corresponding at least one function of a functional component of the first elevator car is replaced by the substitute function provided by the at least one auxiliary device , and the operation of the elevator system is continued by use of the substitute function provided; characterized in that a protected region is formed around the first elevator car , into which region only the at least one auxiliary device is allowed to be brought, wherein the at least one auxiliary device is brought to the first elevator car by use of means for monitoring the distance to the first elevator car . a shaft system comprising at least one vertical elevator shaft ; and a plurality of elevator cars , each comprising a plurality of functional components for carrying out different functions, wherein in a special operating mode of the elevator system at least one auxiliary device is associated to a first elevator car , wherein the at least one auxiliary device provides a substitute function for at least one function of one of the functional components of the first elevator car , wherein the corresponding at least one function of a functional component of the first elevator car is replaced by the substitute function provided by the at least one auxiliary device , and the operation of the elevator system is continued by use of the substitute function provided; characterized in that a protected region is formed around the first elevator car , into which region only the at least one auxiliary device is allowed to be brought, wherein the at least one auxiliary device is brought to the first elevator car by use of means for monitoring the distance to the first elevator car .
A communication method, comprising: receiving , by a second device, a first indication information carried in a physical broadcast channel in a first synchronization signal block sent by a first device, the first synchronization signal block not being associated with control information, the first indication information indicating a frequency domain resource location of a second synchronization signal block, and the second synchronization signal block being associated with the control information; and receiving , by the second device, the second synchronization signal block sent by the first device. receiving , by a second device, a first indication information carried in a physical broadcast channel in a first synchronization signal block sent by a first device, the first synchronization signal block not being associated with control information, the first indication information indicating a frequency domain resource location of a second synchronization signal block, and the second synchronization signal block being associated with the control information; and receiving , by the second device, the second synchronization signal block sent by the first device.
A method of cutting a product , in particular a food product, using a cutting apparatus for cutting a product, wherein the cutting apparatus comprises a product receiver for receiving the product; a feeding apparatus for feeding the product in a direction substantially perpendicular to a cutting plane defined by a cutting blade and by a cutting edge; and a gripper (10A-10L) having a suction device for gripping an end section of the product, characterized in that a vacuum which is variable in time and which may differ locally is generated by the suction device, with a first suction power being provided at the start of a gripping process for gripping the product in order to securely grip the product; and in that a second suction power which is smaller than the first suction power is provided during an adjoining cutting process of the product; and/or in that the suction power is increased in an end phase of a cutting process of the product.