mhurhangee/patent-ind-claim-en huggingface dataset:
A cross-flow apparatus for producing an emulsion or dispersion by dispersing a first phase in a second phase; said cross-flow apparatus comprising: an outer tubular sleeve provided with a first inlet at a first end ; an emulsion outlet ; and a second inlet , distal from and inclined relative to the first inlet ; a tubular membrane provided with a plurality of pores and adapted to be positioned inside the tubular sleeve ; and an insert adapted to be located inside the tubular membrane , said insert comprising an inlet end and an outlet end, characterized in that each of the inlet end and the outlet end is provided with chamfered region, the chamfered region being provided with a plurality of orifices and a furcation plate. an outer tubular sleeve provided with a first inlet at a first end ; an emulsion outlet ; and a second inlet , distal from and inclined relative to the first inlet ; a tubular membrane provided with a plurality of pores and adapted to be positioned inside the tubular sleeve ; and an insert adapted to be located inside the tubular membrane , said insert comprising an inlet end and an outlet end, characterized in that each of the inlet end and the outlet end is provided with chamfered region, the chamfered region being provided with a plurality of orifices and a furcation plate.
A pool of adaptors, each adaptor comprising a double-stranded portion at one end and a single stranded portion comprising two non-hybridizable strands at the opposite end, and further comprising at least one primer-binding site and at least one barcode in each single-stranded portion, wherein the barcodes on each adaptor in the pool are in a known relationship, wherein the relationship between the barcodes is reverse complementarity,
A method for performing an in situ proximity assay, comprising: (a) labeling a biological sample with a plurality of conjugates that each comprise: i. a binding agent that binds to a site or sequence in the sample and ii. a first oligonucleotide; (b) ligating pairs of first oligonucleotides together, in situ, in the presence of a splint oligonucleotide to produce a first product, wherein the ligation is splinted by the splint oligonucleotide; (c) ligating the ends of the splint oligonucleotide to a first reporter oligonucleotide and a second reporter oligonucleotide, in situ, to produce a reporter probe, wherein: i. the ligation is splinted by the first product, ii. the first reporter oligonucleotide has a 5' end that is exonuclease resistant and a 3' hydroxyl; iii. the second reporter oligonucleotide has a 3' end that is exonuclease resistant and a 5' phosphate; and iv. the reporter probe is exonuclease resistant; and (d) treating the sample with an exonuclease to remove unligated reporter oligonucleotides, splint oligonucleotide, and first oligonucleotide. (a) labeling a biological sample with a plurality of conjugates that each comprise: i. a binding agent that binds to a site or sequence in the sample and ii. a first oligonucleotide; (b) ligating pairs of first oligonucleotides together, in situ, in the presence of a splint oligonucleotide to produce a first product, wherein the ligation is splinted by the splint oligonucleotide; (c) ligating the ends of the splint oligonucleotide to a first reporter oligonucleotide and a second reporter oligonucleotide, in situ, to produce a reporter probe, wherein: i. the ligation is splinted by the first product, ii. the first reporter oligonucleotide has a 5' end that is exonuclease resistant and a 3' hydroxyl; iii. the second reporter oligonucleotide has a 3' end that is exonuclease resistant and a 5' phosphate; and iv. the reporter probe is exonuclease resistant; and i. the ligation is splinted by the first product, ii. the first reporter oligonucleotide has a 5' end that is exonuclease resistant and a 3' hydroxyl; iii. the second reporter oligonucleotide has a 3' end that is exonuclease resistant and a 5' phosphate; and iv. the reporter probe is exonuclease resistant; and (d) treating the sample with an exonuclease to remove unligated reporter oligonucleotides, splint oligonucleotide, and first oligonucleotide.
A laundry dryer comprising a body ; a drum which is disposed in the body and wherein the laundry is loaded; a motor which is configured to drive and rotate the drum ; a belt which is configured to transmit the movement of the motor to the drum ; a fan which is configured to provide the circulation of the drying air in the drying cycle; an evaporator which is configured to dehumidify the drying air; a condenser which is configured to heat the dehumidified drying air; a first temperature sensor which is disposed at the air outlet of the drum and which is configured to measure the temperature of the drying air at the outlet of the drum ; and a second temperature sensor which is disposed between the evaporator and the condenser and which is configured to measure the temperature of the drying air passed over the evaporator characterized by a control unit which is configured to determine whether the rotation of the drum is locked or not by using the temperature difference value between the temperature value received from the first temperature sensor and the temperature value received from the second temperature sensor .
A method for synchronizing a light grid having a transmitter unit with a plurality of transmitters , a receiver unit with a plurality of receivers , a transmitter control unit , and a receiver control unit , wherein each transmitter forms a transmitter/receiver pair with an associated receiver and a transmitter transmits a transmission beam to the associated receiver when the transmitter is activated, characterized in that the receiver control unit first activates all receivers and the transmitter control unit activates one after the other all transmitters once in a cycle (T) with a steady cycle having uniform interval spacing, wherein at least two transmission beams in the cycle (T) form a first and a second synchronization transmission beam which are transmitted at a defined time interval (D) from one another and have a common identifier by which they are distinguished from the other transmission beams , wherein the first synchronization transmission beam, the second synchronization transmission beam , and the transmission beams are transmitted in an order which forms a defined sequence which is known to the transmitter control unit and the receiver control unit, and the defined time interval (D) between two synchronization transmission beams in the cycle (T) is unique, so that in the cycle (T) a defined time interval (D) between two synchronization transmission beams occurs only once, and wherein the receiver control unit determines the time difference between the arrival of the first second synchronization transmission beam and the second synchronization transmission beam and, on the basis of the defined distance (D), unambiguously allocates the first synchronization transmission beam and the second synchronization transmission beam within the totality of the transmission beams in the cycle (T).
A compound of the formula (I), or a pharmaceutically acceptable salt thereof: wherein A 1 is N or CR 1 ; A 2 is N or CR 3 ; and wherein only a single one of A 1 and A 2 may be N; R 1 is selected from the group consisting of: H, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 3-4 cycloalkyl, -C 1-4 alkyl-OR A1 and -C(O)NR A1 R B1 ; R 2 is selected from the group consisting of: H, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 3-4 cycloalkyl, -C 1-4 alkyl-OR A2 and -C(O)NR A2 R B2 ; R 3 is selected from H, C 1-4 alkyl, C 1-4 haloalkyl, C 3-4 cycloalkyl, -C 1-4 alkyl-OH and - C(O)NR A3 R B3 ; each X is independently H or F, provided at least one X is F; B 1 and B 2 are independently CH or N; R 4 is halo; X 1 is O or CH 2 ; R A1 , R B1 , R A2 , R B2 , R A3 and R B3 are each independently selected from: H and C 1-4 alkyl; a is an integer selected from 0, 1 or 2; b is an integer selected from 0, 1 or 2; a + b is 0, 1, 2 or 3; and n is 0, 1 or 2; with the following provisos: (i) R 1 , R 2 and R 3 are not all H; (ii) when A 1 is N, at least one of R 2 and R 3 is C 1-4 alkyl or C 1-4 haloalkyl; (iii) when A 2 is N, at least one of R 1 and R 2 is C 1-4 alkyl or C 1-4 haloalkyl; (iv) when A 1 is CR 1 , R 1 is -CH 2 OH and B 1 is N, then R 2 is not H; and (v) when A 1 is CR 1 , R 1 is -CN and B 2 is N, then R 2 is not H. A 1 is N or CR 1 ; A 2 is N or CR 3 ; and wherein only a single one of A 1 and A 2 may be N; R 1 is selected from the group consisting of: H, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 3-4 cycloalkyl, -C 1-4 alkyl-OR A1 and -C(O)NR A1 R B1 ; R 2 is selected from the group consisting of: H, CN, C 1-4 alkyl, C 1-4 haloalkyl, C 3-4 cycloalkyl, -C 1-4 alkyl-OR A2 and -C(O)NR A2 R B2 ; R 3 is selected from H, C 1-4 alkyl, C 1-4 haloalkyl, C 3-4 cycloalkyl, -C 1-4 alkyl-OH and - C(O)NR A3 R B3 ; each X is independently H or F, provided at least one X is F; B 1 and B 2 are independently CH or N; R 4 is halo; X 1 is O or CH 2 ; R A1 , R B1 , R A2 , R B2 , R A3 and R B3 are each independently selected from: H and C 1-4 alkyl; a is an integer selected from 0, 1 or 2; b is an integer selected from 0, 1 or 2; a + b is 0, 1, 2 or 3; and n is 0, 1 or 2; with the following provisos: (i) R 1 , R 2 and R 3 are not all H; (ii) when A 1 is N, at least one of R 2 and R 3 is C 1-4 alkyl or C 1-4 haloalkyl; (iii) when A 2 is N, at least one of R 1 and R 2 is C 1-4 alkyl or C 1-4 haloalkyl; (iv) when A 1 is CR 1 , R 1 is -CH 2 OH and B 1 is N, then R 2 is not H; and (v) when A 1 is CR 1 , R 1 is -CN and B 2 is N, then R 2 is not H. (i) R 1 , R 2 and R 3 are not all H; (ii) when A 1 is N, at least one of R 2 and R 3 is C 1-4 alkyl or C 1-4 haloalkyl; (iii) when A 2 is N, at least one of R 1 and R 2 is C 1-4 alkyl or C 1-4 haloalkyl; (iv) when A 1 is CR 1 , R 1 is -CH 2 OH and B 1 is N, then R 2 is not H; and (v) when A 1 is CR 1 , R 1 is -CN and B 2 is N, then R 2 is not H.
A thrombectomy system comprising: an elongate shaft having a distal region that defines a distal end , the elongate shaft defining a high pressure lumen and a low pressure lumen , the low pressure lumen terminating at a low pressure lumen distal opening and the high pressure lumen terminating near an end of the low pressure lumen at a high pressure lumen distal opening ; and a suction source in fluid communication with the low pressure lumen ; and a source of pressurized fluid in fluid communication with the high pressure lumen ; wherein the low pressure lumen extends to the distal end of the elongate shaft ; wherein the high pressure lumen distal opening is a jet orifice that is proximal of said distal end of the elongate shaft and provides a fluid jet which traverses the low pressure lumen ; and characterized in that the system comprises an expandable capture basket disposed proximate the end of the low pressure lumen ; wherein the thrombectomy system further comprises one or more high pressure fluid jets disposed in or near the expandable capture basket . an elongate shaft having a distal region that defines a distal end , the elongate shaft defining a high pressure lumen and a low pressure lumen , the low pressure lumen terminating at a low pressure lumen distal opening and the high pressure lumen terminating near an end of the low pressure lumen at a high pressure lumen distal opening ; and a suction source in fluid communication with the low pressure lumen ; and a source of pressurized fluid in fluid communication with the high pressure lumen ; wherein the low pressure lumen extends to the distal end of the elongate shaft ; wherein the high pressure lumen distal opening is a jet orifice that is proximal of said distal end of the elongate shaft and provides a fluid jet which traverses the low pressure lumen ; and characterized in that the system comprises an expandable capture basket disposed proximate the end of the low pressure lumen ; wherein the thrombectomy system further comprises one or more high pressure fluid jets disposed in or near the expandable capture basket .
A communication method, implemented by an intermediate node, wherein the intermediate node is between a first provider edge, PE, node and a second PE node on a working segment routing traffic engineering, SR-TE, tunnel, the first PE node is connected to the second PE node by separately using the working SR-TE tunnel and a protection SR-TE tunnel, the first PE node is an ingress node of the working SR-TE tunnel, the second PE node is an egress node of the working SR-TE tunnel, and the method comprises: a.) determining (S 601) that a port bit error fault occurs on the intermediate node; b.) receiving (S 602), by using the working SR-TE tunnel, a first OAM packet from the first PE node; c.) encapsulating (S 603) identification information in the first OAM packet to obtain a second OAM packet, wherein the identification information is used to identify that signal degradation, SD, occurs in the working SR-TE tunnel, wherein the second OAM packet is a continuity check message, CCM; and d.) sending (S 604) the second OAM packet to the second PE node by using the working SR-TE tunnel, wherein the second OAM packet is used to instruct the second PE node to switch to the protection SR-TE tunnel to communicate with the first PE node. a.) determining (S 601) that a port bit error fault occurs on the intermediate node; b.) receiving (S 602), by using the working SR-TE tunnel, a first OAM packet from the first PE node; c.) encapsulating (S 603) identification information in the first OAM packet to obtain a second OAM packet, wherein the identification information is used to identify that signal degradation, SD, occurs in the working SR-TE tunnel, wherein the second OAM packet is a continuity check message, CCM; and d.) sending (S 604) the second OAM packet to the second PE node by using the working SR-TE tunnel,
A method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, wherein the method comprises the steps of: (a) providing a first liquid composition comprising at least one RNA, (b) providing a second liquid composition comprising at least one cationic or polycationic compound, (c) introducing the first liquid composition and the second liquid composition into at least one reactor, wherein the first liquid composition and the second liquid composition are mixed with a blend time of 5 seconds or less, measured by the method described in example 3 of the description, and (d) recovering the product liquid composition comprising the nanoparticle comprising the at least one RNA and the at least one cationic or polycationic compound from the reactor. (a) providing a first liquid composition comprising at least one RNA, (b) providing a second liquid composition comprising at least one cationic or polycationic compound, (c) introducing the first liquid composition and the second liquid composition into at least one reactor, wherein the first liquid composition and the second liquid composition are mixed with a blend time of 5 seconds or less, measured by the method described in example 3 of the description, and (d) recovering the product liquid composition comprising the nanoparticle comprising the at least one RNA and the at least one cationic or polycationic compound from the reactor.
A method for transmitting channel state information-reference signals, CSI-RSs, for 8 antenna ports at a base station, the method comprising: transmitting the CSI-RSs for the 8 antenna ports, the CSI-RSs being mapped, according to a predetermined pattern, to a data region of a downlink subframe having a normal cyclic prefix, CP, configuration, wherein the downlink subframe having the normal CP configuration has 14 orthogonal frequency division multiplexing, OFDM, symbols, where the OFDM symbol index starts from 0; wherein the predetermined pattern is defined such that the CSI-RSs for the 8 antenna ports are mapped to only two consecutive OFDM symbols in the data region of the downlink subframe and are mapped to four subcarrier locations in each of the two consecutive OFDM symbols, wherein the downlink subframe has: 14 OFDM symbols in a time domain and 12 subcarriers in a frequency domain, wherein the two consecutive OFDM symbols are OFDM symbols to which User Equipment-specific, UE-specific, reference signals are allowed to be mapped, wherein the four subcarrier locations defined in the predetermined pattern include two consecutive subcarrier locations and two other consecutive subcarrier locations separated therefrom by a predetermined number of subcarriers, wherein the CSI-RSs are subjected to code division multiplexing, CDM, using orthogonal codes, such that in the downlink subframe CSI-RSs for two antenna ports are mapped to the same OFDM symbol symbols and the same subcarrier, and wherein the CSI-RSs for two antenna ports are spread in the time domain by CDM over the two consecutive OFDM symbols at the same subcarrier location. transmitting the CSI-RSs for the 8 antenna ports, the CSI-RSs being mapped, according to a predetermined pattern, to a data region of a downlink subframe having a normal cyclic prefix, CP, configuration, wherein the downlink subframe having the normal CP configuration has 14 orthogonal frequency division multiplexing, OFDM, symbols, where the OFDM symbol index starts from 0; wherein the predetermined pattern is defined such that the CSI-RSs for the 8 antenna ports are mapped to only two consecutive OFDM symbols in the data region of the downlink subframe and are mapped to four subcarrier locations in each of the two consecutive OFDM symbols, wherein the downlink subframe has: 14 OFDM symbols in a time domain and 12 subcarriers in a frequency domain, wherein the two consecutive OFDM symbols are OFDM symbols to which User Equipment-specific, UE-specific, reference signals are allowed to be mapped, wherein the four subcarrier locations defined in the predetermined pattern include two consecutive subcarrier locations and two other consecutive subcarrier locations separated therefrom by a predetermined number of subcarriers, wherein the CSI-RSs are subjected to code division multiplexing, CDM, using orthogonal codes, such that in the downlink subframe CSI-RSs for two antenna ports are mapped to the same OFDM symbol symbols and the same subcarrier, and wherein the CSI-RSs for two antenna ports are spread in the time domain by CDM over the two consecutive OFDM symbols at the same subcarrier location.
Decontamination unit which is capable of being at least partially immersed in a basin of a water treatment plant, open at its upper part and capable of cooperating with said basin such that a contaminated aqueous flow containing dissolved organic matter and suspended solid matter and microorganisms can supply the upstream side of the aerated basin and provide, at the outlet of said unit , a flow of decontaminated, clarified water, the unit comprising: - an outlet (14, F1) which discharges the decontaminated water to the outside of the basin ; - at least one region separator crossed by the contaminated aqueous flow from the basin , one of the faces called the "upstream face" being designed to directly receive the contaminated aqueous flow from the basin, while the other face called the "downstream face" is designed to supply the outlet (14, F1), the region separator therefore delimiting two zones, one upstream and one downstream of the separator, the liquids of the two regions delimited by the separator being subjected to the same external pressure P 0 when it is in operation in the aerated basin ; on its upstream face, the separator comprising a grid covered, on the upstream side of the basin , by a fibrous or filamentary layer which is designed to stop the majority of the suspended solid matter from the feed stream of the basin ; the downstream face of the separator being covered with a screen which is permeable to the liquid of the basin that is at least partially decontaminated by its passage through the upstream face of the separator and designed to stop the solid matter having passed through the fibrous layer and the grid , a space being provided between the grid and the screen and opening out at the lower part of the screen on a device for discharging solid matter located in the lower part of the screen . - an outlet (14, F1) which discharges the decontaminated water to the outside of the basin ; - at least one region separator crossed by the contaminated aqueous flow from the basin , one of the faces called the "upstream face" being designed to directly receive the contaminated aqueous flow from the basin, while the other face called the "downstream face" is designed to supply the outlet (14, F1), the region separator therefore delimiting two zones, one upstream and one downstream of the separator, the liquids of the two regions delimited by the separator being subjected to the same external pressure P 0 when it is in operation in the aerated basin ;
A file storage method, applied to a terminal, characterized by comprising: obtaining a to-be-stored file, and performing splitting processing on the to-be-stored file to obtain N sub-files corresponding to the to-be-stored file (S101), wherein N is an integer greater than 1; sending the N sub-files to an InterPlanetary File System, IPFS, and receiving M pieces of address information corresponding to the N sub-files returned by the IPFS (S102), wherein M is an integer greater than 1 and less than or equal to N; generating an address set corresponding to the to-be-stored file according to the M pieces of address information, and encrypting the address set to obtain an address set ciphertext (S103); and sending the address set ciphertext to a blockchain network and receiving a target index value returned by the blockchain network (S104), wherein the target index value is used to identify the address set ciphertext. obtaining a to-be-stored file, and performing splitting processing on the to-be-stored file to obtain N sub-files corresponding to the to-be-stored file (S101), wherein N is an integer greater than 1; sending the N sub-files to an InterPlanetary File System, IPFS, and receiving M pieces of address information corresponding to the N sub-files returned by the IPFS (S102), wherein M is an integer greater than 1 and less than or equal to N; generating an address set corresponding to the to-be-stored file according to the M pieces of address information, and encrypting the address set to obtain an address set ciphertext (S103); and sending the address set ciphertext to a blockchain network and receiving a target index value returned by the blockchain network (S104), wherein the target index value is used to identify the address set ciphertext.
Hand-operated power tool (10; 110; 210), in particular grinder, cutting device or screwdriver, with a tool motor (12; 112; 212) for the motorised driving of a tool holder (13; 213) provided for holding a tool , and with a fan wheel (30; 130; 230) of a fan arrangement (50; 150; 250), mounted together with the tool motor (12; 112; 212) in a casing of the hand-operated power tool (10; 110; 210), for generating a cooling airflow for cooling the hand-operated power tool (10; 110; 210), in particular the tool motor (12; 112; 212), wherein it has a fan motor (31; 131; 231) separate from the tool motor (12; 112; 212) for the motorised drive of the fan wheel (30; 130; 230), characterised in that the fan wheel (30; 130; 230) driveable by the fan motor (31; 131; 231) and/or the fan motor (31; 131; 231) are mounted rotatably on the motor shaft of the tool motor (12; 112; 212) by means of a bearing assembly.