mhurhangee/patent-ind-claim-en huggingface dataset:
A method for processing a substrate , the method comprising: positioning a first major surface of a substrate on a chuck , the substrate having a plurality of structures formed on the first major surface, wherein each of the plurality of structures are positioned in a respective cavity of a plurality of cavities (510A-510C) formed in a chucking surface of the chuck ; applying a first pressure to the first major surface through a plurality of ports formed in the chucking surface while applying a second pressure in pairs of the cavities (510A-510C), the first pressure being different than the second pressure; and forming a plurality of structures on a second major surface of the substrate. positioning a first major surface of a substrate on a chuck , the substrate having a plurality of structures formed on the first major surface, wherein each of the plurality of structures are positioned in a respective cavity of a plurality of cavities (510A-510C) formed in a chucking surface of the chuck ; applying a first pressure to the first major surface through a plurality of ports formed in the chucking surface while applying a second pressure in pairs of the cavities (510A-510C), the first pressure being different than the second pressure; and forming a plurality of structures on a second major surface of the substrate.
A mower-conditioner for cutting and conditioning crop material, comprising a mower unit for cutting crop material and a conditioner unit that is configured to condition the cut crop material, a drive input that is configured to receive a rotational drive from an external drive unit, and a drive transmission system that is configured to transmit rotary drive from the drive input to the mower unit and the conditioner unit, wherein the drive transmission system includes a continuously variable transmission (CVT) that transmits rotary drive between the mower unit and the conditioner unit with a variable speed ratio, wherein the CVT includes an adjuster mechanism that includes at least one actuator for adjusting the speed ratio of the CVT; characterised by a control system for controlling operation of the actuator, wherein the control system includes a sensor that senses at least one operational condition of the mower-conditioner and a control unit that receives a sensor signal from the sensor and controls operation of the actuator so as to adjust the speed ratio of the CVT in response to said sensor signal.
Nucleic acid aptamer binding specifically to STAT5, preferably to STAT5B, said aptamer being caracterised in that it comprises the sequence SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 57, or a variant having at least 90% of sequence identity with SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 57.
A copolymer comprising a structural unit derived from 1,3,7-octatriene and a structural unit derived from styrene and having a molecular weight distribution (Mw/Mn) of 1.5 or less, wherein the molecular weight distribution is measured according to the description.
Calibration device for measuring the signal-inducing sensing deflection l Tr of a tactile measuring probe which is clamped on a tool head and has a deflectable sensing element having a sensing surface , the calibration device containing a detector , preferably a camera or a laser measuring instrument, having a field of view for detecting the sensing surface of the sensing element , a reference element having a reference surface , and a calculation unit , characterized in that the reference surface of the reference element is arranged with respect to the field of view of the detector in such a way that, in the event of signal-inducing contact of the sensing surface of the sensing element with the reference surface , the sensing surface or parts of the sensing surface lies or lie in the field of view of the detector , the detector and the calculation unit being suitable for calculating the precise position of the sensing element from the detected part of the sensing surface and the calculation unit further being suitable for calculating the signal-inducing sensing deflection from (a) the position of the clamping point of the measuring probe on the tool head and (b) the calculated position of the sensing element which in a deflected and signal-inducing state touches the reference surface and (c) a length, known in advance, of the measuring probe or a calculated position of the nondeflected sensing element .
Travel suitcase, which comprises: - a rigid or semi-rigid containment body ; - two or more wheels mechanically associated with said containment body susceptible of advancing on the ground and each comprising: - a hub connected by means of a pin to said containment body , and - an annular rolling tread , susceptible of coming into contact with the ground, externally mounted on said hub and delimiting an internal air chamber by means of two sidewalls of which at least one sidewall having a terminal portion and a curved connector portion ; - at least one handle for pulling said suitcase with the wheels that advance on the ground; characterized in that said hub comprises: - an annular support body provided with a through seat orthogonal to the radial extension of the annular support body and with a radially projecting retention crest , positioned so as to close said air chamber ; - at least one retention plate , mechanically coupled to said annular support body by means of anchorage means and provided with one peripheral portion interacting with said terminal portion of at least one sidewall of said annular rolling tread , in order to keep the latter in a retention relationship against the crest of said annular support body . - a rigid or semi-rigid containment body ; - two or more wheels mechanically associated with said containment body - a hub connected by means of a pin to said containment body , and - an annular rolling tread , susceptible of coming into contact with the ground, externally mounted on said hub and delimiting an internal air chamber by means of two sidewalls of which at least one sidewall having a terminal portion and a curved connector portion ; - at least one handle for pulling said suitcase with the wheels that advance on the ground; - an annular support body provided with a through seat orthogonal to the radial extension of the annular support body and with a radially projecting retention crest , positioned so as to close said air chamber ; - at least one retention plate , mechanically coupled to said annular support body by means of anchorage means and provided with one peripheral portion interacting with said terminal portion of at least one sidewall of said annular rolling tread , in order to keep the latter in a retention relationship against the crest of said annular support body .
Air-cooled electric machine comprising a housing , a rotor connected to a rotor shaft for conjoint rotation, a stator having axially arranged cooling channels , end shields which are arranged on the drive side (AS) and non-drive side (NAS) of the machine and contain bearings for rotatably receiving the rotor shaft , a coupling which is arranged on the drive-side end of the shaft and has a machine-side coupling part and a transmission-side coupling part for connection to a transmission , and comprising a fan connected to the rotor shaft for guiding the cooling air through the axial cooling channels , the coupling being arranged on the side of the bearing that faces the transmission , which bearing is contained in the end shield arranged on the drive side (AS), the fan being arranged on the drive side (AS) of the machine and being surrounded by the housing such that the cooling air (L) can be guided from an air inlet of the housing on the drive side (AS) through the axial cooling channels to an air outlet on the non-drive side (NAS), the housing surrounding the end shield arranged on the drive side (AS) and the transmission-side coupling part being arranged outside the housing , characterised in that the fan is arranged on the machine-side coupling part so as to be integrated in the coupling .
A method of identifying a selected phenotype associated with a synthetic modular polypeptide in a cell ex vivo / in vitro, the method comprising: a) introducing a barcoded library of nucleic acids into host cells, thereby generating a heterogeneous population of genetically modified host cells, wherein the barcoded library of nucleic acids comprises a plurality of members, each of which plurality of members comprises a nucleotide sequence encoding a different synthetic modular polypeptide, the nucleotide sequence comprising: a coding region comprising two or more coding sequences encoding two or more variable modules, wherein the two or more coding sequences are in-frame with each other; and a barcode region comprising two or more unique barcodes, wherein each variable module in the coding region is correlated with a specific unique barcode in the barcode region; b) identifying a genetically modified host cell within the heterogeneous population that displays the selected phenotype in response to a stimulus; and (c) from the identified host cell of (b), identifying and/or quantifying the barcode region by sequencing, thereby identifying the synthetic modular polypeptide and/or module thereof producing the selected phenotype; wherein the host cells are selected from mammalian primary cells and immortalized cell lines and the synthetic modular polypeptide is a modular receptor. a) introducing a barcoded library of nucleic acids into host cells, thereby generating a heterogeneous population of genetically modified host cells, wherein the barcoded library of nucleic acids comprises a plurality of members, each of which plurality of members comprises a nucleotide sequence encoding a different synthetic modular polypeptide, the nucleotide sequence comprising: a coding region comprising two or more coding sequences encoding two or more variable modules, wherein the two or more coding sequences are in-frame with each other; and a barcode region comprising two or more unique barcodes, wherein each variable module in the coding region is correlated with a specific unique barcode in the barcode region; b) identifying a genetically modified host cell within the heterogeneous population that displays the selected phenotype in response to a stimulus; and (c) from the identified host cell of (b), identifying and/or quantifying the barcode region by sequencing, thereby identifying the synthetic modular polypeptide and/or module thereof producing the selected phenotype;
R(-)-ketamine or a pharmacologically acceptable salt thereof for use in the treatment of a depressive symptom, the treatment comprising administering R(-)-ketamine or the pharmacologically acceptable salt thereof to a subject, wherein the subject has been diagnosed with having a depressive symptom, in an amount effective to treat the depressive symptom, wherein the R(-)-ketamine or the pharmacologically acceptable salt thereof does not contain S(+)-ketamine or a pharmacologically acceptable salt thereof, and wherein the depressive symptom accompanies depression in children or adults, obsessive-compulsive disorder, or post-traumatic stress disorder.
An elastomer composite comprising a diene-based elastomer containing an antioxidant comprising a combination of tris(nonyl phenyl) phosphite (TNPP) and tetramethylethylene diamine (TMEDA), characterized in that the weight ratio of TNPP to TMEDA is in a range of from 4/1 to 50/1.
Combination of a profile and a hinge for a window or a door of a building, the hinge comprising an accessory for the sideways adjustment of the position of a hinge leaf of the hinge on the profile of the window or door, wherein the profile is provided with a first groove and with a second groove and the hinge leaf is provided with a thickened section that in the mounted situation of the position of the hinge leaf on the profile is slidably engaged in the first groove with a certain sideways play , characterised in that the hinge leaf is provided with a slot that, in the mounted situation of the hinge leaf on the profile , extends in a direction that runs obliquely with respect to the longitudinal direction of the profile , and in that the hinge is provided with an accessory that is constructed as a sliding piece that in the mounted situation of the hinge on the profile is affixed between the hinge leaf and the profile and which is provided with a guide rib with which the sliding piece is movably affixed in the second groove of the profile and which is provided with a peg that is guided in the slot of the hinge leaf .
A method for performing a localizated heating of metal pipes connected to each other by welding at one end and partially coated in lenght by a layer of plastic coating , each of said metal pipes being surrounded by at least a coil , , said method comprising the steps of: - heating directly by induction a central zone of the metal pipe corresponding to an end portion of two metal pipe connected to each other by welding, said central zone being free of protective plastic coating ; - heating indirectly and simultaneously by irradiation of two sectors , adjacent to said central zone of the metal pipes and provided with protective plastic coating . - heating directly by induction a central zone of the metal pipe corresponding to an end portion of two metal pipe connected to each other by welding, said central zone being free of protective plastic coating ; - heating indirectly and simultaneously by irradiation of two sectors , adjacent to said central zone of the metal pipes and provided with protective plastic coating .
Industrial truck (101; 201), comprising: a chassis (102; 202), a front axle (103; 203) mounted on the chassis (102; 202), two front wheels (VRL, VRR) provided on opposite longitudinal ends of the front axle (103; 203), one load-lifting means (106; 206) provided in a front region on the chassis (102; 202), preferably in front of the front wheels (VRL, VRR), a front drive motor (111; 211) coupled to the two front wheels (VRL, VRR) by means of a differential gear (110; 210) in order to drive these wheels, a rear wheel (HR; HRL, HRR) mounted on the chassis (102; 202) by means of a pivot plate (104; 204L, 204R) such that said rear wheel can rotate about a rear wheel vertical axis (A; AL, AR), a steering mechanism (120; 220) coupled to the pivot plate (104; 204L, 204R) for adjusting a steering angle of the rear wheel (HR; HRL, HRR), a rear drive motor (105; 205; 205R, 205L) coupled to the rear wheel (HR; HRL; HRR) in order to drive said rear wheel, and a control device (130; 230) which is designed to distribute a currently required driving torque for the industrial truck (101; 201) to the front drive motor (111; 211) and the rear drive motor (105; 205; 205R, 205L), specifically depending on at least one current steering angle of the rear wheel (HR, HRL, HRR).
Device for application of a liquid medium (W) to a roll , particularly to a work roll of a roll stand and/or to rolling material, a slab or a pre-strip and/or for removal of the liquid medium (W), wherein the device comprises at least one spray nozzle , at least one spray nozzle row or at least one cooling bar for spraying the medium (W) and at least one plate element , which is constructed for collection of the medium (W), wherein the roll is constructed for the rolling of rolling material , wherein the rolling material, the slab or the pre-strip is conveyed in a conveying direction (F) and wherein the plate element has on its surfaces at least one guide element constructed for deflection of medium (W) in a transverse direction (Q), which lies horizontally (H) and transversely to the conveying direction (F) characterised in that the at least one guide element is formed to be flat and is arranged at angle (β) to the transverse direction on the plate element , wherein the angle (β) is between 5° and 80°, or the at least one guide element is formed to be curved.
A compound of formula Ia, Ib or Ic: wherein: n is 1 or 2; R N is H or Me; R 1 is optionally one or more halo or methyl groups; R 2a and R 2b are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH; R 2c and R 2d (if present) are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH; R 3a and R 3b are independently selected from H and Me; R 4a is selected from OH, -NH 2 , -C(=O)NH 2 , and -CH 2 OH; R 4b is either H or Me; R 5 is either H or Me; A is either (i) optionally substituted phenyl; (ii) optionally substituted naphthyl; or (iii) optionally substituted C 5-12 heteroaryl; wherein the optional substituents on A are independently selected from the group consisting of: C 1-4 alkyl, C 1-4 fluoroalkyl, C 3-6 cycloalkyl, C 5-6 heteroaryl, C 5-6 heteroaryl methyl, C 4-6 heterocyclyl, C 4-6 heterocyclyl methyl, phenyl, benzyl, halo, amido, amidomethyl, acylamido, acylamidomethyl, C 1-4 alkyl ester, C 1-4 alkyl ester methyl, C 1-4 alkyl carbamoyl, C 1-4 alkyl carbamoyl methyl, C 1-4 alkylacyl, C 1-4 alkylacyl methyl, phenylcarbonyl, carboxy, carboxymethyl, ether, amino, aminomethyl, sulfonamido, sulfonamino, sulfone, sulfoxide, nitrile and nitrilemethyl and when A is phenyl, the optional substituent may also be a fused C 5-6 N 1 -containing heterocyclic ring. n is 1 or 2; R N is H or Me; R 1 is optionally one or more halo or methyl groups; R 2a and R 2b are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH; (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH; R 2c and R 2d (if present) are independently selected from the group consisting of: (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH; (i) F; (ii) H; (iii) Me; and (iv) CH 2 OH; R 3a and R 3b are independently selected from H and Me; R 4a is selected from OH, -NH 2 , -C(=O)NH 2 , and -CH 2 OH; R 4b is either H or Me; R 5 is either H or Me; A is either (i) optionally substituted phenyl; (ii) optionally substituted naphthyl; or (iii) optionally substituted C 5-12 heteroaryl; (i) optionally substituted phenyl; (ii) optionally substituted naphthyl; or (iii) optionally substituted C 5-12 heteroaryl; wherein the optional substituents on A are independently selected from the group consisting of: C 1-4 alkyl, C 1-4 fluoroalkyl, C 3-6 cycloalkyl, C 5-6 heteroaryl, C 5-6 heteroaryl methyl, C 4-6 heterocyclyl, C 4-6 heterocyclyl methyl, phenyl, benzyl, halo, amido, amidomethyl, acylamido, acylamidomethyl, C 1-4 alkyl ester, C 1-4 alkyl ester methyl, C 1-4 alkyl carbamoyl, C 1-4 alkyl carbamoyl methyl, C 1-4 alkylacyl, C 1-4 alkylacyl methyl, phenylcarbonyl, carboxy, carboxymethyl, ether, amino, aminomethyl, sulfonamido, sulfonamino, sulfone, sulfoxide, nitrile and nitrilemethyl and when A is phenyl, the optional substituent may also be a fused C 5-6 N 1 -containing heterocyclic ring.
Catheter for dialysis, in particular for long-term use, having a proximal end for insertion into a blood vessel, having a middle wall extending along a longitudinal axis l and forming a midplane E w , wherein the middle wall separates an introduction lumen from a removal lumen , and wherein the removal lumen has at the proximal end a removal opening for the removal of blood, and the introduction lumen has at the proximal end an introduction opening for the introduction of purified blood, characterized in that the removal opening is located in a plane E 1 which intersects the midplane E w in a section line s 1 at an acute angle w 1 , wherein the section line s 1 and the longitudinal axis 1 enclose an acute angle α, and that the introduction opening is located in a plane E 2 which intersects the midplane E w in a section line s 2 at an acute angle w 2 , wherein the section line s 1 and the section line s 2 enclose an angle β which lies in the range from 60° to 120°.
Tyre for a wheel intended to equip a manually transportable vehicle, comprising a composition based on at least one diene elastomer, at least one reinforcing filler, and a crosslinking system comprising at least one radical polymerization initiator, and a cocrosslinking agent selected from the group consisting of (meth)acrylate compounds, maleimide compounds, allyl compounds, vinyl compounds and their mixtures.
A flame-retardant vibration isolation rubber composition comprising: the following ingredient (A) as a rubber component; and the following ingredients (B) to (D), wherein (A) is diene-based rubber, (B) is a halogen-based flame retardant, (C) is a metal molybdate compound, and (D) is a metal hydroxide, and further comprising: a 12-hydroxystearic acid compound as ingredient (E). the following ingredient (A) as a rubber component; and the following ingredients (B) to (D), wherein (A) is diene-based rubber, (B) is a halogen-based flame retardant, (C) is a metal molybdate compound, and (D) is a metal hydroxide, and (A) is diene-based rubber, (B) is a halogen-based flame retardant, (C) is a metal molybdate compound, and (D) is a metal hydroxide, and further comprising: a 12-hydroxystearic acid compound as ingredient (E).
A system for manufacturing three-dimensional structures, the system comprising a plurality of printing stations for performing parallel printing in an confined space, wherein each printing station comprises a carrier , a deposition unit with at least one nozzle arranged for dispensing filaments of build material paste through an opening area thereof and a station controller configured to operate the deposition unit for deposition of filaments of a build material paste on the carrier in an interconnected arrangement in a plurality of stacked layers in order to form one or more three-dimensional structures, the at least one nozzle and the carrier being relatively moveable with respect to each other, characterized in that the system comprises a reservoir unit that is configured to house the build material paste, wherein the deposition unit is coupled to the reservoir unit , wherein the reservoir unit includes at least one reservoir arranged outside of the confined space, wherein the deposition unit includes at least a first nozzle and a second nozzle , wherein the first nozzle is coupled to a first reservoir for first feeding build material paste and the second nozzle is coupled to a second reservoir for second feeding build material paste, and wherein the first nozzle is further coupled to the second reservoir , and the second nozzle is further coupled to the first reservoir .
Porous catalyst support consisting of a material comprising a natural sheet silicate, with ZrO 2 being present in dispersed form in the material, characterized in that the natural sheet silicate is an acid-treated, calcined bentonite, with the ZrO 2 being uniformly distributed in the material and the ZrO 2 being present in particulate form, the catalyst support being configured as a sphere and having a hardness of greater than/equal to 20 N, where the hardness is determined as set forth in the description.
Cylinder head of piston engine extending longitudinally including a cylinder head body and a flange in at least one element , the flange to be interposed between a combustion chamber and the cylinder head body , comprising an upper face opposite the cylinder head body and an opposed lower face to be disposed facing the combustion chamber and being mounted on the cylinder head body , in which the flange and the body are assembled by bolts for fixing the flange to the cylinder head , which are situated towards the periphery of the flange and body , and by at least one component for fixing the cylinder head to the flange including one threaded end for fixing in a corresponding orifice in the flange , said orifice being located closer to the centre of the flange than the fixing bolts , characterised in that the cylinder head body is made of a material having a volumetric mass and hardness lower than those of the material that constitutes the flange and in that the clamping force of the fixing component or components is greater than or equal to twice the clamping force of the flange fixing bolts.