A culture apparatus comprising: a heat-insulated casing including an inner case surrounding a culture space , an outer case surrounding the inner case , and a front surface, the heat-insulated casing having an opening in the front surface; a box-shaped heat-insulated door configured to open and close the opening of the heat-insulated casing ; one or more heaters provided to one or more inner surfaces of the inner case and an inner wall surface of the heat-insulated door and configured to heat the culture space , the inner wall surface being adapted to face the culture space when the door is closed ; and a control unit configured for turning on the heaters , the heaters including one or more first heaters and one or more second heaters , characterized in that the control unit is further configured so that the first heaters are turned on, when a temperature of the culture space is controlled to a first temperature to incubate a culture in the culture space and when a temperature of the culture space is controlled to a second temperature to make the culture space sterile, the second temperature being higher than the first temperature, and the second heaters are turned on when a temperature of the culture space is controlled to the second temperature to make the culture space sterile. a heat-insulated casing including an inner case surrounding a culture space , an outer case surrounding the inner case , and a front surface, an inner case surrounding a culture space , an outer case surrounding the inner case , and a front surface, the heat-insulated casing having an opening in the front surface; a box-shaped heat-insulated door configured to open and close the opening of the heat-insulated casing ; one or more heaters provided to one or more inner surfaces of the inner case and an inner wall surface of the heat-insulated door and configured to heat the culture space , the inner wall surface being adapted to face the culture space when the door is closed ; and a control unit configured for turning on the heaters , the heaters including one or more first heaters and one or more second heaters , characterized in that the control unit is further configured so that the first heaters are turned on, when a temperature of the culture space is controlled to a first temperature to incubate a culture in the culture space and when a temperature of the culture space is controlled to a second temperature to make the culture space sterile, the second temperature being higher than the first temperature, and the second heaters are turned on when a temperature of the culture space is controlled to the second temperature to make the culture space sterile. one or more first heaters and one or more second heaters , characterized in that the control unit is further configured so that the first heaters are turned on, when a temperature of the culture space is controlled to a first temperature to incubate a culture in the culture space and when a temperature of the culture space is controlled to a second temperature to make the culture space sterile, the second temperature being higher than the first temperature, and the second heaters are turned on when a temperature of the culture space is controlled to the second temperature to make the culture space sterile. <EOS>