mhurhangee/patent-ind-claim-en huggingface dataset:
A cartridge device for lubricating a machine (M), preferably a clipping machine, the machine (M) having a pneumatic system (S) and a pump unit (P) driven by the pneumatic system (S), the cartridge device comprising: - a cartridge container for accommodating a collapsible reservoir containing a supply of lubricant, the cartridge container having a longitudinal axis (L) defining a longitudinal direction, wherein the cartridge container comprises a first end portion and a second end portion located opposite the first end portion in the longitudinal direction, and - a first closure element for detachably coupling the first end portion of the cartridge container to a suction side of the pump unit (P), wherein the first closure element has a delivery opening for supplying lubricant contained within the cartridge container to the suction side of the pump unit (P), - wherein the first closure element is detachably coupleable to the first end portion of the cartridge container , the first end portion of the cartridge container being configured so as to allow for the collapsible reservoir to be inserted into and removed from the cartridge container , characterized in that the first closure element comprises at least one bar bridging over the delivery opening of the first closure element for detaining the collapsible reservoir within the cartridge container . - a cartridge container for accommodating a collapsible reservoir containing a supply of lubricant, the cartridge container having a longitudinal axis (L) defining a longitudinal direction, wherein the cartridge container comprises a first end portion and a second end portion located opposite the first end portion in the longitudinal direction, and - a first closure element for detachably coupling the first end portion of the cartridge container to a suction side of the pump unit (P), wherein the first closure element has a delivery opening for supplying lubricant contained within the cartridge container to the suction side of the pump unit (P), - wherein the first closure element is detachably coupleable to the first end portion of the cartridge container , the first end portion of the cartridge container being configured so as to allow for the collapsible reservoir to be inserted into and removed from the cartridge container ,
An optical fiber comprising: a core ; and a clad coating the core , wherein the clad includes a refractive-index varying region in which a refractive index increases in a direction from an inner circumferential side toward an outer circumferential side, and a predetermined region in which the refractive index is constant, and the predetermined region being adjacent to the core ; and wherein in the refractive-index varying region , an amount of change in the refractive index per unit length in a radial direction is larger on the inner circumferential side than on the outer circumferential side. a core ; and a clad coating the core , wherein the clad includes a refractive-index varying region in which a refractive index increases in a direction from an inner circumferential side toward an outer circumferential side, and a predetermined region in which the refractive index is constant, and the predetermined region being adjacent to the core ; and wherein in the refractive-index varying region , an amount of change in the refractive index per unit length in a radial direction is larger on the inner circumferential side than on the outer circumferential side.
An apparatus for the shaping of plastics material preforms into plastics material containers with a transport device which transports the plastics material preforms along a pre-set transport path, wherein the transport device has a movable station carrier which is arranged at least indirectly on a stationary base carrier and on which are arranged a plurality of shaping stations , wherein these shaping stations have in each case blow moulding devices which form cavities in each case inside which the plastics material preforms are capable of being shaped to form the plastics material containers and these blow moulding devices are arranged in each case on blow mould carriers , wherein the apparatus has a changing device which is suitable for and intended for removing at least the blow moulding devices from the blow mould carriers thereof and/or arranging blow moulding devices on the blow mould carriers , wherein this changing device has a gripping device for gripping the blow moulding device , wherein this gripping device is movable in at least two different directions and is pivotable about at least three different pivot axes (A1, A2...A6) and wherein the gripping device comprises active elements which are configured and intended to establish a form and force fit with the blow moulding device, wherein the gripping device is configured to establish a form fit connection between the two side parts of the blow moulding device and further to establish a force fit connection between said blow mould halves and the bottom form , characterized in that this second connection with the bottom form is achieved via corresponding engagement elements of the bottom form .
A polymerization process for the production of high density polyethylene by polymerization of ethylene in the presence of a catalyst composition comprising a chromium compound, an alcohol and a support material characterized in that the alcohol is a secondary cyclic alcohol, the support material is silica support material, the chromium compound is selected from chromium acetate, chromium acetyl acetonate, chromium acetate hydroxide and chromium trioxide and the catalyst composition comprises additionally a titanium compound.
Stimulation device for a pressure wave massage for the clitoris, comprising a chamber with an outer end forming an opening for being situated on the clitoris, and an inner end provided with generating means for generating pressure waves in a longitudinal direction (L), wherein the chamber comprises a side wall arranged between the outer end and the inner end , provided with deflector means for deflecting pressure waves which protrude from the side wall to cause turbulences in the pressure waves, characterised in that the thickness in the longitudinal direction of the deflector means decreases in the transverse direction towards the central longitudinal axis of the chamber .
Oxygen reduced stored blood for use in transfusion therapy for the treatment of hemorrhagic trauma in a hemorrhagic trauma subject having an elevated lactate level, wherein said oxygen reduced stored blood comprises an oxygen saturation (SO 2 ) level of 20% or less, and wherein said elevated lactate level is reduced to between 0.5 and 2.5 millimole per liter (mmol/L) after providing said oxygen reduced stored blood to said hemorrhagic trauma subject.
Multi-pole component for an electric machine , comprising - an upper side , - a lower side , - a first magnetic pole which possesses a surface on the upper side , - a second magnetic pole which possesses a surface in a tangential direction adjacent to the first magnetic pole on the upper side and - a soft-magnetic device , - wherein the soft-magnetic device has a recess between the first magnetic pole and the second magnetic pole , - wherein a vertical direction is aligned from the upper side to the lower side at right angles to a tangential direction , - wherein the first magnetic pole has a permanent magnet with a magnetization in one direction , - wherein the second magnetic pole does not have a permanent magnet, - wherein the surface of the second magnetic pole has a recess for actuating a fastening device for the multi-pole component , - wherein the fastening device has an actuation device for actuating the fastening device from the upper side or from the lower side of the multi-pole component and - wherein the recess on the surface of the second magnetic pole has a part of an edge, which can be extended to one edge by a further multi-pole component arranged consecutively in a tangential direction. - an upper side , - a lower side , - a first magnetic pole which possesses a surface on the upper side , - a second magnetic pole which possesses a surface in a tangential direction adjacent to the first magnetic pole on the upper side and - a soft-magnetic device , - wherein the soft-magnetic device has a recess between the first magnetic pole and the second magnetic pole , - wherein a vertical direction is aligned from the upper side to the lower side at right angles to a tangential direction , - wherein the first magnetic pole has a permanent magnet with a magnetization in one direction , - wherein the second magnetic pole does not have a permanent magnet, - wherein the surface of the second magnetic pole has a recess for actuating a fastening device for the multi-pole component , - wherein the fastening device has an actuation device for actuating the fastening device from the upper side or from the lower side of the multi-pole component and - wherein the recess on the surface of the second magnetic pole has a part of an edge, which can be extended to one edge by a further multi-pole component arranged consecutively in a tangential direction.
A method of manufacturing filter elements for aerosol generating products , especially filter plug elements for smoking articles, comprising: processing bulk filter material to provide or form a substantially continuous strand (D) of the filter material ; and covering the substantially continuous strand (D) of filter material with at least one layer of sheet material to form an elongate filter member (R, 20); the method comprising the step of forming perforations or holes in the elongate filter member (R, 20) by forming the perforations or holes in the at least one layer of sheet material and into or through the filter material covered or wrapped by the at least one layer of sheet material after the step of covering the strand (D) of filter material with the at least one layer of sheet material, characterized in that the method is a method of manufacturing discrete or individual filter elements . processing bulk filter material to provide or form a substantially continuous strand (D) of the filter material ; and covering the substantially continuous strand (D) of filter material with at least one layer of sheet material to form an elongate filter member (R, 20); the method comprising the step of forming perforations or holes in the elongate filter member (R, 20) by forming the perforations or holes in the at least one layer of sheet material and into or through the filter material covered or wrapped by the at least one layer of sheet material after the step of covering the strand (D) of filter material with the at least one layer of sheet material, characterized in that the method is a method of manufacturing discrete or individual filter elements .
Injector for fuel injection, comprising: an injector housing , a movable injection needle, which is arranged in the injector housing and has an injection needle tip, and an injection needle seat for accommodating the injection needle tip, wherein a contact pairing of injection needle and injection needle seat represents a mechanical switch , which assumes a closed state upon contact between injection needle tip and injection needle seat and an open state upon interruption of contact, the injector has an input line and an output line for controlling a movement of the injection needle, the input line and output line each represent a contact of a coil which forms part of an electromagnet , the injector is characterized in that the switch has a first connection which is connected to the input line and a second connection which is connected to the injector housing , and a resistor (R) is connected between the first connection of the switch and the input line , wherein the resistor (R) is a high-temperature resistor chip. an injector housing , a movable injection needle, which is arranged in the injector housing and has an injection needle tip, and an injection needle seat for accommodating the injection needle tip, wherein a contact pairing of injection needle and injection needle seat represents a mechanical switch , which assumes a closed state upon contact between injection needle tip and injection needle seat and an open state upon interruption of contact, the injector has an input line and an output line for controlling a movement of the injection needle, the input line and output line each represent a contact of a coil which forms part of an electromagnet , the injector is characterized in that the switch has a first connection which is connected to the input line and a second connection which is connected to the injector housing , and a resistor (R) is connected between the first connection of the switch and the input line , wherein the resistor (R) is a high-temperature resistor chip.
A method for the identification of a polynucleotide encoding an enzyme of interest in a microfluidic device, said method comprising the steps of: a) providing an emulsion of microfluidic droplets comprising a library of polynucleotides encoding one or more enzyme, wherein each droplet comprises at most a single member of the library, and expressing the library of polynucleotides to produce the one or more enzyme; b) introducing an aliquot comprising a substrate for the one or more enzyme into each droplet, wherein the presence of one or more active enzyme of interest will convert the substrate into a screenable product; c) determining positive droplets that contain the screenable product above a predetermined threshold level which, in turn, also determines the negative droplets; d) introducing an aliquot of concentrated PCR solution comprising nucleotides, a suitable DNA polymerase and a set of PCR primers which allows PCR amplification of the polynucleotides encoding the one or more enzyme of interest into each positive droplets determined in step (c); and introducing an aliquot of a solution which results in DNA denaturation as well as enzyme denaturation and cell lysis into the negative droplets determined in step (c); e) cloning or PCR amplifying the polynucleotide encoding the one or more enzyme of interest from the positive droplets; and f) identifying a polynucleotide encoding an enzyme of interest from the cloned or PCR amplified polynucleotides in step (e). a) providing an emulsion of microfluidic droplets comprising a library of polynucleotides encoding one or more enzyme, wherein each droplet comprises at most a single member of the library, and expressing the library of polynucleotides to produce the one or more enzyme; b) introducing an aliquot comprising a substrate for the one or more enzyme into each droplet, wherein the presence of one or more active enzyme of interest will convert the substrate into a screenable product; c) determining positive droplets that contain the screenable product above a predetermined threshold level which, in turn, also determines the negative droplets; d) introducing an aliquot of concentrated PCR solution comprising nucleotides, a suitable DNA polymerase and a set of PCR primers which allows PCR amplification of the polynucleotides encoding the one or more enzyme of interest into each positive droplets determined in step (c); and introducing an aliquot of a solution which results in DNA denaturation as well as enzyme denaturation and cell lysis into the negative droplets determined in step (c); e) cloning or PCR amplifying the polynucleotide encoding the one or more enzyme of interest from the positive droplets; and f) identifying a polynucleotide encoding an enzyme of interest from the cloned or PCR amplified polynucleotides in step (e).
A linker-drug compound of structure (I): wherein: X is a leaving group selected from the group consisting of; wherein the leaving group, X, and the sulfur atom, S, are bound via a disulfide bond; R 1 and R 2 together with the carbon atom to which they are bound form a four- to six-membered carbon ring or a four- to six-membered carbon ring comprising an oxygen heteroatom; Sp is a spacer wherein n is 0 or 1; and D is a drug moiety selected from a maytansine, an auristatin, a dolastatin, a pyrrolobenzodiazepine (PBD) monomer or dimer having the structure: wherein n is 0 or 1, a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) monomer or dimer, and a CBI-PBD dimer. X is a leaving group selected from the group consisting of; wherein the leaving group, X, and the sulfur atom, S, are bound via a disulfide bond; R 1 and R 2 together with the carbon atom to which they are bound form a four- to six-membered carbon ring or a four- to six-membered carbon ring comprising an oxygen heteroatom; Sp is a spacer wherein n is 0 or 1; and D is a drug moiety selected from a maytansine, an auristatin, a dolastatin, a pyrrolobenzodiazepine (PBD) monomer or dimer having the structure: wherein n is 0 or 1, a 1-(chloromethyl)-2,3-dihydro-1H-benzo[e]indole (CBI) monomer or dimer, and a CBI-PBD dimer.
Flap for a motor vehicle front side air inlet shutter device , said flap corresponding to a hollow profile obtained by extrusion and having a convex front area intended to be placed in opposition to an airflow when the flap is in a closed end position and a rear area , opposite the front area , intended to be connected to at least one reinforcement borne by the shutter device , characterized in that the rear area has an engagement specific shape that is continuous over the entire length of the flap and the longitudinal axis of which is merged with the pivoting axis (P) of the flap , said engagement specific shape being intended to cooperate with at least one complementary shape borne by the at least one reinforcement , said cooperation being of male-female type such as to allow snap-fitting of the engagement specific shape and of the complementary shape in order to fix the flap on the reinforcement and allow it to be pivotably guided.
A method of assessing or monitor the efficacy of a treatment compound in treating a cancer, or predict responsiveness of a subject having or suspected of having a cancer to a treatment compound, comprising: (a) determining the level of a biomarker in a first sample from a subject having or suspected of having a cancer, who was administered a treatment compound; and (b) comparing the level of the biomarker from step (a) to the level of the same protein obtained from a reference sample, wherein a change in the biomarker level as compared to the reference sample is indicative of the efficacy of the compound in treating the cancer or responsiveness of the subject to the treatment compound, wherein the treatment compound is lenalidomide, thalidomide, pomalidomide, Compound A, or Compound B; wherein the biomarker is casein kinase 1, alpha 1 (CSNK1A1), or ZFP91; wherein the cancer is selected from a group consisting of (i) lymphoma, such as diffuse large B-cell lymphoma (DLBCL), (ii) multiple myeloma (MM), (iii) myelodysplastic syndrome (MDS) and (iv) acute myeloid leukemia (AML). (a) determining the level of a biomarker in a first sample from a subject having or suspected of having a cancer, who was administered a treatment compound; and (b) comparing the level of the biomarker from step (a) to the level of the same protein obtained from a reference sample, wherein a change in the biomarker level as compared to the reference sample is indicative of the efficacy of the compound in treating the cancer or responsiveness of the subject to the treatment compound, (ii) multiple myeloma (MM), (iii) myelodysplastic syndrome (MDS) and (iv) acute myeloid leukemia (AML).
A vehicle partition comprising an upper partition half and a lower partition half which are arranged relative to one another in such a way that they overlap in the vertical direction in an overlap region , so that a channel is formed in this overlapping region , characterized in that air gaps and/or air channels are provided in the channel to accomplish a venting function.
A system for improving the power efficiency of communications satellites having an array of RF receive antenna elements , the system comprising: a beamformer configured to generate a plurality of beamformed signals based on a plurality of input signals received via the RF receive antenna elements; a plurality of power amplifiers configured to amplify a first plurality of signals corresponding to the plurality of beamformed signals; an array of transmit antenna elements , wherein each transmit antenna element is configured to transmit an RF signal based on an output of one of the power amplifiers ; and an intermodulation decorrelator configured to decorrelate intermodulation products of the plurality of beamformed signals prior to conversion of the plurality of beamformed signals from linear signals to nonlinear signals, wherein the intermodulation products are spatially and/or temporally decorrelated by adding an in-band dither, an out-of-band dither, performing in-band crest-factor reduction, out-of-band-crest factor reduction, or using delta-sigma modulation. a beamformer configured to generate a plurality of beamformed signals based on a plurality of input signals received via the RF receive antenna elements; a plurality of power amplifiers configured to amplify a first plurality of signals corresponding to the plurality of beamformed signals; an array of transmit antenna elements , wherein each transmit antenna element is configured to transmit an RF signal based on an output of one of the power amplifiers ; and an intermodulation decorrelator configured to decorrelate intermodulation products of the plurality of beamformed signals prior to conversion of the plurality of beamformed signals from linear signals to nonlinear signals, wherein the intermodulation products are spatially and/or temporally decorrelated by adding an in-band dither, an out-of-band dither, performing in-band crest-factor reduction, out-of-band-crest factor reduction, or using delta-sigma modulation.
A casing for an exhaust turbocharger turbine, configured to accommodate a turbine rotor driven by exhaust gas and forming a spiral scroll as a path through which the exhaust gas is supplied to the turbine rotor, wherein the scroll has a tubular introduction portion introducing the exhaust gas and an annular portion extending from the introduction portion, and a surface area of an inner wall surface of the scroll decreases from a winding start position toward a winding end position, characterized in that the annular portion includes a first range from the winding start position to a predetermined angle and a second range from the predetermined angle to the winding end position wherein the first range is lower than the second range in surface roughness of the inner wall surface.