mhurhangee/patent-ind-claim-en huggingface dataset:
A method of detecting an analyte of interest in a sample comprising: a. binding the analyte to: (i) a capture reagent on a surface, said surface comprising the capture reagent for the analyte, wherein the capture reagent is an antibody; (ii) a first detection reagent for the analyte that is linked to a first nucleic acid probe; and (iii) a second detection reagent for the analyte that is linked to a second nucleic acid probe, wherein the first detection reagent and the second detection reagent are antibodies; thereby forming a complex on the surface comprising the capture reagent, the analyte and the first and second detection reagents, wherein the surface also comprises an anchoring reagent comprising an anchoring oligonucleotide sequence; b. using an extension process that requires the first and second nucleic acid probes to be in proximity to one or two connector sequences that hybridize to the first and second nucleic acid probes, ligating the one or two connector sequences to form a circular template, and extending the second nucleic acid probe, by rolling circle amplification of the circular template, to form an extended sequence comprising an anchoring sequence complement that is complementary to the anchoring oligonucleotide sequence; c. hybridizing the anchoring oligonucleotide sequence to the anchoring sequence complement of the extended sequence; and d. measuring the amount of extended sequence bound to the surface. a. binding the analyte to: (i) a capture reagent on a surface, said surface comprising the capture reagent for the analyte, wherein the capture reagent is an antibody; (ii) a first detection reagent for the analyte that is linked to a first nucleic acid probe; and (iii) a second detection reagent for the analyte that is linked to a second nucleic acid probe, wherein the first detection reagent and the second detection reagent are antibodies; thereby forming a complex on the surface comprising the capture reagent, the analyte and the first and second detection reagents, wherein the surface also comprises an anchoring reagent comprising an anchoring oligonucleotide sequence; b. using an extension process that requires the first and second nucleic acid probes to be in proximity to one or two connector sequences that hybridize to the first and second nucleic acid probes, ligating the one or two connector sequences to form a circular template, and extending the second nucleic acid probe, by rolling circle amplification of the circular template, to form an extended sequence comprising an anchoring sequence complement that is complementary to the anchoring oligonucleotide sequence; c. hybridizing the anchoring oligonucleotide sequence to the anchoring sequence complement of the extended sequence; and d. measuring the amount of extended sequence bound to the surface.
Device for inhibiting electrical activity of an excitable cell by application of a light pulse, characterised in that it consists of a substrate of electrically insulating material and a photoreactive film layered directly on one another, wherein the said photoreactive film includes a layer of semiconducting polymer material and a layer of dielectric material placed on the layer of semiconducting polymer material , and has an interface surface provided by the layer of dielectric material which can be placed in contact with an excitable cell and an electrolyte solution , said layer of semiconducting polymer material having a thickness of between 50 and 1000 nm, said semiconducting polymer material being an intrinsic semiconductor having a bandgap between 1 and 2 eV, an electrical conductivity of an order of magnitude which is less or equal to 10 -5 S/m and mobility of charge carriers of an order of magnitude less than or equal to 10 -4 cm 2 V/s at ambient temperature, in which the photoreactive film, when contacted with the said excitable cell and electrolyte solution, produces a potential difference across the said interface surface which will induce hyperpolarisation of the membrane of the said excitable cell after absorbing light, wherein the light radiation is within the absorption window for the semiconducting polymer material.
Apparatus for safeguarding the leaf movements of an automatic revolving door (36; 12) using sensors, having a sensor system comprising a sensor unit (42; 16) which can be arranged on the hinge side of the door leaf (38; 18) and/or a sensor unit (44; 22) which can be arranged on the counter-hinge side of the door leaf (38; 18) and having a door controller which communicates with the sensor system , wherein a respective sensor unit (42, 44; 16, 22) comprises an at least substantially flat distance scanner, wherein the sensor unit (42, 44; 16, 22) comprises a flat light scanner as the flat distance scanner, and the sensor system and/or the door controller is/are configured in such a manner that, in a respective automatically performed learning cycle during an opening and/or closing cycle of the door leaf (38; 18), a respective sensor unit (42, 44; 16, 22) measures the distances between the respective sensor unit (42, 44; 16, 22) and the surroundings of the door leaf (38; 18) for successive door opening angles (α) in each case in a hinge-side or counter-hinge-side plane , determines a three-dimensional image of the surroundings from the measured values obtained in the various planes on the basis of the door opening angle (α) as a function of the distances between the respective sensor unit (42, 44; 16, 22) and the surroundings, as measured in the various planes, and as a function of the door opening angle (α) and stores the three-dimensional image of the surroundings which is determined in this manner, characterized in that a respective sensor unit (42, 44; 14, 20) is configured in such a manner that, during a respective opening or closing cycle of the door leaf , it measures the distances (xn(t)) between the respective sensor unit (42, 44; 16, 22) and the surroundings along a line for a respective current door opening angle (α(t)) in the respective plane as a function of the respective current door opening angle (α(t)).
A method for the automatic calibration of slides comprising the steps: - Providing a slide frame (4; 210) having a plurality of slide seats, wherein the slide frame is calibrated which establishes the positioning coordinates of the slide seats with respect to a microscope scanning system , and wherein the positioning coordinates are saved in a storage medium that can be read out by the microscope scanning system ; - Providing at least one slide (212a - 212h; 300) with a calibration mark ; - Arranging the at least one slide (212a - 212h; 300) in one of the slide seats of the slide frame (4; 210); - Arranging the slide frame with the slide (212a - 212h; 300) on a scanning table (10; 200) of the microscope scanning system ; - Detecting mark coordinates of the calibration mark based on a detection of the calibration mark of the slide (212a -212h; 300) by the microscope scanning system ; - Detecting a deviation between the position coordinates of the slide seat and the mark coordinates of the slide (212a -212h; 300); and - Saving the detected deviation in a storage medium that can be connected to the slide (212a - 212h; 300). - Providing a slide frame (4; 210) having a plurality of slide seats, wherein the slide frame is calibrated which establishes the positioning coordinates of the slide seats with respect to a microscope scanning system , and wherein the positioning coordinates are saved in a storage medium that can be read out by the microscope scanning system ; - Providing at least one slide (212a - 212h; 300) with a calibration mark ; - Arranging the at least one slide (212a - 212h; 300) in one of the slide seats of the slide frame (4; 210); - Arranging the slide frame with the slide (212a - 212h; 300) on a scanning table (10; 200) of the microscope scanning system ; - Detecting mark coordinates of the calibration mark based on a detection of the calibration mark of the slide (212a -212h; 300) by the microscope scanning system ; - Detecting a deviation between the position coordinates of the slide seat and the mark coordinates of the slide (212a -212h; 300); and - Saving the detected deviation in a storage medium that can be connected to the slide (212a - 212h; 300).
An electromagnetic connect/disconnect system , comprising: an electromagnet comprising a coil and a coil housing ; a rotatable and axially slidable slide ring located between said coil housing and a sliding collar , said slide ring comprising a radially outer surface , a radially inner surface , a first end and a second end ; said sliding collar comprising a first portion and a second portion , said first portion is located directly radially inward from said slide ring , said second portion defining a first set of axially extending teeth ; a return spring ; and an output gear comprising a second set of axially extending teeth for selective engagement with said sliding collar first set of teeth wherein the return spring is configured to axially move the sliding collar to engage the first set of teeth on the sliding collar with the second set of teeth on the output gear . an electromagnet comprising a coil and a coil housing ; a rotatable and axially slidable slide ring located between said coil housing and a sliding collar , said slide ring comprising a radially outer surface , a radially inner surface , a first end and a second end ; said sliding collar comprising a first portion and a second portion , said first portion is located directly radially inward from said slide ring , said second portion defining a first set of axially extending teeth ; a return spring ; and an output gear comprising a second set of axially extending teeth for selective engagement with said sliding collar first set of teeth wherein the return spring is configured to axially move the sliding collar to engage the first set of teeth on the sliding collar with the second set of teeth on the output gear .
An apparatus (10; 102) comprising at least one processor (20; 110) and at least one memory (40; 42; 112) including computer program code, the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus to: initiate performance of an operation on a first device (10; 102; 200) prior to receiving an indication that a second device is proximate the first device; receive the indication that the second device is proximate the first device; receive an indication of at least one functional capability of the second device; and cause transfer of the operation from the first device to the second device based on a comparison of at least one functional capability of the first device with the at least one functional capability of the second device and further based on the operation. initiate performance of an operation on a first device (10; 102; 200) prior to receiving an indication that a second device is proximate the first device; receive the indication that the second device is proximate the first device; receive an indication of at least one functional capability of the second device; and cause transfer of the operation from the first device to the second device based on a comparison of at least one functional capability of the first device with the at least one functional capability of the second device and further based on the operation.
Device for damping vibrations of a cable , the device comprising: - a support , - at least one first damper for damping the vibrations of the cable , the first damper comprising a first element and a second element movable telescopically with respect to one another, the second element being intended to be fastened to the cable , the first element having a distal end and a proximal end with respect to the cable , and - a fastener arranged on the support to fasten the first damper to the support , characterised in that the fastener is fastened to the first damper at a location along the first damper located away from the distal end of the first element in the direction of the proximal end , and wherein, in a configuration of use of the damping device in which the support is fastened to a receiving structure and the first damper is fastened to the cable and to the support , the first damper is inclined with respect to a vertical plane in which the cable extends and substantially in which the support is fastened to the receiving structure. - a support , - at least one first damper for damping the vibrations of the cable , the first damper comprising a first element and a second element movable telescopically with respect to one another, the second element being intended to be fastened to the cable , the first element having a distal end and a proximal end with respect to the cable , and - a fastener arranged on the support to fasten the first damper to the support ,
A monitoring system comprising: an acquirer configured to acquire, from one or more monitoring cameras that capture an image of a work area in which presented information to be input is input to an input terminal, a captured image captured by the one or more monitoring cameras; an extractor configured to extract the information to be input from the captured image acquired by the acquirer ; an encryption processor configured to encrypt the information to be input extracted by the extractor ; and a generator configured to: embed, in the encrypted information to be input, key information for decrypting the encrypted information to be input to generate a partial image; and replace the information to be input in the acquired captured image with the generated partial image to generate a replaced image in which the information to be input is made invisible. an acquirer configured to acquire, from one or more monitoring cameras that capture an image of a work area in which presented information to be input is input to an input terminal, a captured image captured by the one or more monitoring cameras; an extractor configured to extract the information to be input from the captured image acquired by the acquirer ; an encryption processor configured to encrypt the information to be input extracted by the extractor ; and a generator configured to: embed, in the encrypted information to be input, key information for decrypting the encrypted information to be input to generate a partial image; and replace the information to be input in the acquired captured image with the generated partial image to generate a replaced image in which the information to be input is made invisible. embed, in the encrypted information to be input, key information for decrypting the encrypted information to be input to generate a partial image; and replace the information to be input in the acquired captured image with the generated partial image to generate a replaced image in which the information to be input is made invisible.
A method of isolating barrel-like proteases, the method comprising isolating barrel-like proteases from a biological sample containing said barrel-like proteases under conditions that maintain the content of the barrel-like protease-processed peptides in said barrel-like proteases upon said isolation, thereby isolating the barrel-like proteases, wherein said conditions that maintain the content of the barrel-like protease-processed peptides in said barrel-like proteases comprise a chemical cross-linking agent and wherein said conditions that maintain the content of the barrel-like protease-processed peptides in said barrel-like proteases comprise contacting the barrel-like proteases with a peptidase inhibitor and wherein said barrel-like protease -processed peptides are non-tryptic peptides.
A process for preparing compounds of formula I, in which R 1 is in each case independently selected from hydrogen, halogen, C 1 -C 6 -alkyl and C 1 -C 6 -halogenalkyl; R 2 is in each case independently selected from hydrogen and halogen; R 10 is in each case independently selected from H, halogen, O(R 95 ), C 1 -C 6 -alkyl and C 1 -C 6 -halogenalkyl; wherein R 95 is C 1 -C 6 -alkyl, C 1 -C 6 -halogenalkyl; comprising the following steps: (i) selective chlorination of a compound of the formula II wherein R 1 , R 2 and R 10 are as defined above with a chlorinating agent, wherein the chlorinating agent is trichloroisocyanuric acid, to provide a compound of the formula III (ii) and a selective fluorination of the compound of the formula III using a fluorination agent, wherein the fluorination agent is KF or a polyhydrofluoride complex of a trialkylamine to provide the compound of the formula I. R 1 is in each case independently selected from hydrogen, halogen, C 1 -C 6 -alkyl and C 1 -C 6 -halogenalkyl; R 2 is in each case independently selected from hydrogen and halogen; R 10 is in each case independently selected from H, halogen, O(R 95 ), C 1 -C 6 -alkyl and C 1 -C 6 -halogenalkyl; wherein R 95 is C 1 -C 6 -alkyl, C 1 -C 6 -halogenalkyl; R 95 is C 1 -C 6 -alkyl, C 1 -C 6 -halogenalkyl; (i) selective chlorination of a compound of the formula II wherein R 1 , R 2 and R 10 are as defined above with a chlorinating agent, wherein the chlorinating agent is trichloroisocyanuric acid, to provide a compound of the formula III (ii) and a selective fluorination of the compound of the formula III using a fluorination agent, wherein the fluorination agent is KF or a polyhydrofluoride complex of a trialkylamine to provide the compound of the formula I.
A food or beverage box comprising a container and a lid designed to hermetically close the container , a bottom of the container having protrusions extending outwards, the lid having recesses opening outwards, each protrusion being capable of entering at least partially into each recess , each protrusion is located respectively to the right of a corresponding recess when the lid hermetically closes the container , characterized in that the number of protrusions is less than the number of recesses .
Device to be inserted in a heeled shoe, said device comprising a base or sole, said base or sole comprising a transversal bar made of a flexible and damping material, delimited by two lines extending from the inside to the outside of the foot of a wearer and standing behind the metatarsal heads of the foot of the wearer and in front of the base of these metatarsals, so as to decrease the stresses on the metatarsal heads and to limit the sliding of the foot and the intensity of the impact on the ground, while walking.
A head protective member for placement in a child safety seat for restraining an infant , comprising, a block body configured to be placed between a sidewall of the child safety seat and a neck of the infant , wherein the block body includes a first side that is contactable with the neck of the infant , a second side that is contactable with the sidewall and whose height (H) is higher than the first side , and an inclined face placed between an upper end of the first side and an upper end of the second side ; wherein: the inclined face is contactable with a lower jaw or a cheek of the infant ; and the block body further includes a bottom that is placed between a lower end of the first side and a lower end of the second side and is contactable with a shoulder of the infant ; characterized in that : the block body is configured in such a manner that when a head of the infant starts to rotate after the neck moves sideways and a sideways movement of the neck is restricted by the first side , the block body becomes sandwiched between the shoulder and the lower jaw or the cheek of the infant and creates a reactive force (F1) from the inclined face and a reactive force (F2) from the bottom , allowing kinetic energy of the head to be absorbed. the inclined face is contactable with a lower jaw or a cheek of the infant ; and the block body further includes a bottom that is placed between a lower end of the first side and a lower end of the second side and is contactable with a shoulder of the infant ;
A hose storage unit for storing a hose at a tap , comprising: a storage hook adapted to receive the hose ; a tap connector adapted to fluidly connect the hose and the tap ; and an adaptor removably coupled with the tap and engaged with the tap connector , wherein the adaptor fluidly couples the tap with the tap connector , and wherein the storage hook is associated with the adaptor ; wherein a portion of the adapter at a first portion extends out partially in an upward direction from the storage hook to couple with an outlet portion of the tap and a portion of the adapter at a second portion extends out partially in a downward direction from the storage hook to receive the tap connector ; and wherein the storage hook includes a first end and a second end , and a hose receiving portion proximate to the second end ; wherein the hose receiving portion of the storage hook is inclined with respect to a central axis ("Al") of the adaptor ; wherein the storage hook further includes a hole to receive the adaptor , wherein the hole is disposed proximate the first end of the storage hook , characterized in that: a vertical portion extends between the first and the second end , wherein the storage hook comprises a through hole proximate to the first end , wherein the through hole is configured to receive a screw lock allowing selective locking of the storage hook , wherein the storage hook further comprises a first surface and a second surface , wherein the first surface and the second surface include a generally curved shaped profile. a storage hook adapted to receive the hose ; a tap connector adapted to fluidly connect the hose and the tap ; and an adaptor removably coupled with the tap and engaged with the tap connector , wherein the adaptor fluidly couples the tap with the tap connector , and wherein the storage hook is associated with the adaptor ; wherein a portion of the adapter at a first portion extends out partially in an upward direction from the storage hook to couple with an outlet portion of the tap and a portion of the adapter at a second portion extends out partially in a downward direction from the storage hook to receive the tap connector ; and wherein the storage hook includes a first end and a second end , and a hose receiving portion proximate to the second end ; wherein the hose receiving portion of the storage hook is inclined with respect to a central axis ("Al") of the adaptor ; wherein the storage hook further includes a hole to receive the adaptor , wherein the hole is disposed proximate the first end of the storage hook , characterized in that: a vertical portion extends between the first and the second end , wherein the storage hook comprises a through hole proximate to the first end , wherein the through hole is configured to receive a screw lock allowing selective locking of the storage hook , wherein the storage hook further comprises a first surface and a second surface , wherein the first surface and the second surface include a generally curved shaped profile.