mhurhangee/patent-ind-claim-en huggingface dataset:
A method for manufacturing a microneedle array, comprising: a positioning adjustment step (s11) of adjusting positioning of a mold having a plurality of needle-like recessed portions on a front surface , and a drug solution ejection nozzle which ejects a drug solution in a first direction; a relative movement step (s12) of moving the mold and the drug solution ejection nozzle relative to each other to cause a position of each of the plurality of needle-like recessed portions and a position of the drug solution ejection nozzle to coincide with each other in a plan view in the first direction; an ejection step (s13) of ejecting one or more droplets of the drug solution from the drug solution ejection nozzle so as to cause the drug solution to fly and land on each of the plurality of needle-like recessed portions ; and a suction step (s16) of suctioning a rear surface of the mold ; wherein each needle-like recessed portion has an opening diameter of 600 μm or more, and an angle of 30.0 degrees or more with respect to a flat portion of the mold , and an ejection amount of the drug solution ejected to one needle-like recessed portion is 30 nL or more. a positioning adjustment step (s11) of adjusting positioning of a mold having a plurality of needle-like recessed portions on a front surface , and a drug solution ejection nozzle which ejects a drug solution in a first direction; a relative movement step (s12) of moving the mold and the drug solution ejection nozzle relative to each other to cause a position of each of the plurality of needle-like recessed portions and a position of the drug solution ejection nozzle to coincide with each other in a plan view in the first direction; an ejection step (s13) of ejecting one or more droplets of the drug solution from the drug solution ejection nozzle so as to cause the drug solution to fly and land on each of the plurality of needle-like recessed portions ; and a suction step (s16) of suctioning a rear surface of the mold ; wherein each needle-like recessed portion has an opening diameter of 600 μm or more, and an angle of 30.0 degrees or more with respect to a flat portion of the mold , and an ejection amount of the drug solution ejected to one needle-like recessed portion is 30 nL or more.
A Melanoma Differentiation-Associated gene 5 (MDA-5)-encoding polynucleotide or a MDA-5 polypeptide, or a functional-conservative derivative thereof in a therapeutically effective amount for use in treating and preventing recurrence of cancer in a subject in need thereof.
Arrangement with a filter , in particular extractor device, wherein the filter has a first electrically conducting layer , at least one second electrically conducting layer and at least one filter layer arranged between the first layer and the second layer , wherein the filter has at least one third electrically conducting layer , characterised in that the arrangement has an evaluation device , that the first layer is electrically isolated from the filter layer and from the second layer , wherein the second layer is electrically isolated from the filter layer and wherein the evaluation device has at least one capacitance measuring facility which is electrically connected to the first layer and the second layer , that the third layer is electrically isolated from the first layer and from the second layer and from the filter layer , that the evaluation device has at least one further capacitance measuring facility and that the further capacitance measuring facility is electrically connected to the first layer and the third layer .
A method of masking wind turbine noise from a wind turbine , the method comprising: generating masking noise to produce resultant noise with a modulation depth which is less than a modulation depth of the wind turbine noise and an average level which is greater than an average level of the wind turbine noise, wherein the masking noise is un-modulated masking noise with a substantially constant level, the method further comprising measuring a parameter which is directly or indirectly indicative of the modulation depth of the wind turbine noise and controlling an average level of the masking noise in accordance with the parameter so that the average level of the masking noise is greater than or equal to the average level of the wind turbine noise.
Bracket for a transport frame , configured to hold a hub of a wind turbine in place at the transport frame during transport of the hub , characterized by holding means for holding the hub during the transport of the hub and tensioning means mechanically connectable with the holding means and the transport frame for attaching the holding means at the transport frame , for moving the holding means relative to the transport frame , and for moving a contacting portion of the holding means against the hub , which is arranged in a predetermined position on the transport frame .
An ethylene homopolymer having: a melt index determined in accordance with ASTM D1238 at 190°C with a 2160 gram weight greater than or equal to 50 g/10 min; a density of less than or equal to 0.970 g/cm 3 ; a Mn in a range from 5,000 to 20,000 g/mol; and a ratio of Mw/Mn of less than or equal to 4. a melt index determined in accordance with ASTM D1238 at 190°C with a 2160 gram weight greater than or equal to 50 g/10 min; a density of less than or equal to 0.970 g/cm 3 ; a Mn in a range from 5,000 to 20,000 g/mol; and a ratio of Mw/Mn of less than or equal to 4.
Method for the event-controlled retrieval of process data, by using a message broker (MB) set up for a publication/subscription service, said method comprising the following steps: a) a data retrieval component (DQ) generating a request message that contains an associating subject and transmitting the request message to the message broker (MB), and the request message being published by the message broker (MB); b) the data retrieval component (DQ) and/or the message broker (MB) setting up a subscription for response messages to be received from a data provision component (DR) that contain the associating subject of the request message; c) the data provision component (DR) receiving the request message published with the associating subject and setting up a publication/subscription service for messages that contain the associating subject of the request message; d) the data provision component (DR) providing process data requested by the request message, generating a response message containing these process data and the associating subject of the request message, transmitting the response message to the message broker (MB); and conveying a response message published using the publication/subscription service to the data retrieval component (DQ) via the message broker (MB). a) a data retrieval component (DQ) generating a request message that contains an associating subject and transmitting the request message to the message broker (MB), and the request message being published by the message broker (MB); b) the data retrieval component (DQ) and/or the message broker (MB) setting up a subscription for response messages to be received from a data provision component (DR) that contain the associating subject of the request message; c) the data provision component (DR) receiving the request message published with the associating subject and setting up a publication/subscription service for messages that contain the associating subject of the request message; d) the data provision component (DR) providing process data requested by the request message, generating a response message containing these process data and the associating subject of the request message, transmitting the response message to the message broker (MB); and conveying a response message published using the publication/subscription service to the data retrieval component (DQ) via the message broker (MB).
A wave power plant comprising: - a frame construction ; - a plurality of rocking rotors arranged on the frame construction on at least one rotor shaft journaled on the frame construction ; - a drive shaft connected to a generator and journaled in said frame construction ; characterised in - at least one belt drive connection arranged between the rotor shaft and the drive shaft for each rocking rotor - at least one rotor drive wheel is arranged on or integrated with each rocking rotor ; and - at least one first shaft drive wheel arranged on the drive shaft for each rocking rotor , - wherein said at least one belt drive connection comprises a belt portion having - a first end connected to the rotor drive wheel ; and - an opposite end connected to the first shaft drive wheel , - and wherein said belt portion being arranged to wind and unwind on the rotor drive wheel and first shaft drive wheel . - a frame construction ; - a plurality of rocking rotors arranged on the frame construction on at least one rotor shaft journaled on the frame construction ; - a drive shaft connected to a generator and journaled in said frame construction ; characterised in - at least one belt drive connection arranged between the rotor shaft and the drive shaft for each rocking rotor - at least one rotor drive wheel is arranged on or integrated with each rocking rotor ; and - at least one first shaft drive wheel arranged on the drive shaft for each rocking rotor , - wherein said at least one belt drive connection comprises a belt portion having - a first end connected to the rotor drive wheel ; and - an opposite end connected to the first shaft drive wheel , - and wherein said belt portion being arranged to wind and unwind on the rotor drive wheel and first shaft drive wheel .
Optical signal generator comprising - an optical emitter configured to generate a beam of optical radiation, (R) - a first and second beam deflecting element, - a modulator being located between the beam deflecting elements, - a phase shifter located between the beam deflecting elements, - a control unit configured to control the phase-shift of the phase shifter, - wherein the first and second beam deflecting elements, the phase shifter and the modulator are located in the same plane, - wherein the beam generated by the optical emitter is angled relative to said plane, - wherein said first beam deflecting element is configured to deflect the emitter's beam (R) into the plane towards the modulator, said modulator being configured to modulate the emitter's radiation and outputting a modulated radiation, (R') - wherein said second beam deflecting element is configured to deflect the modulated radiation off the plane towards an output port of the signal generator, - wherein the modulator is configured to modulate the emitter's radiation in response to an electrical data signal that is applied to the modulator and comprises a data stream, - wherein the control unit is configured to generate a control signal in order to control the phase-shift of the phase shifter and in order to avoid or reduce an impact of reflected radiation on the emitter's emission characteristic, - wherein the signal generator comprises a memory where a target value is stored and - wherein a control unit is configured to control the phase-shift of the phase shifter according to the stored target value. - an optical emitter configured to generate a beam of optical radiation, (R) - a first and second beam deflecting element, - a modulator being located between the beam deflecting elements, - a phase shifter located between the beam deflecting elements, - a control unit configured to control the phase-shift of the phase shifter, - wherein the first and second beam deflecting elements, the phase shifter and the modulator are located in the same plane, - wherein the beam generated by the optical emitter is angled relative to said plane, - wherein said first beam deflecting element is configured to deflect the emitter's beam (R) into the plane towards the modulator, said modulator being configured to modulate the emitter's radiation and outputting a modulated radiation, (R') - wherein said second beam deflecting element is configured to deflect the modulated radiation off the plane towards an output port of the signal generator, - wherein the modulator is configured to modulate the emitter's radiation in response to an electrical data signal that is applied to the modulator and comprises a data stream, - wherein the control unit is configured to generate a control signal in order to control the phase-shift of the phase shifter and in order to avoid or reduce an impact of reflected radiation on the emitter's emission characteristic, - wherein the signal generator comprises a memory where a target value is stored and - wherein a control unit is configured to control the phase-shift of the phase shifter according to the stored target value.
Support element for spacers comprising a base provided for being placed on a surface elevation pedestal or a joist , which basis is provided with at least a first (10-1) and a second (10-2) window each having a geometry curved according to a line of curvature, each window being provided for applying therein one of the spacers , the first and second window each having a start section and a final section, wherein the windows are provided in such a manner that the spacer can be freely moved in the window in which it is applied and be guided by that window when being moved, characterised in that the line of curvature of the first and second window inclines in a continuous manner towards a centre of the basis, the final section of the first window (10-1b) and the start section of the second window (10-2a) being juxtaposed one to each other in such a manner that a linear axis (I) starting from a centre of the basis in a direction towards an external border of the basis crosses successively the final section of the first window and the start section of the second window.
A textile machine producing cross-wound packages, said machine being equipped with a plurality of workstations arranged next to one another on both longitudinal sides of the machine and having a cross-wound package transport apparatus , the cross-wound package transport apparatus having a first transport device , arranged between the two rows of workstations for conveying cross-wound packages , and a handling apparatus (23, 26; 29, 30) for moving cross-wound packages from the first transport device to a second transport device , characterised in that the handling apparatus is arranged between the end regions of the first transport device .
A heat transport device comprising a circulation route enclosing a refrigerant containing at least one of hydrofluoroolefins (HFOs), hydrochlorofluoroolefins (HCFOs), or hydrochloroolefins (HCOs), wherein heat is transferred by passing through each device disposed in the circulation route, the circulation route comprising a condenser ; an expansion mechanism ; an evaporator ; a compressor ; and a stabilizer container containing an acid scavenger and optionally an antioxidant, the optional antioxidant being at least one member selected from the group consisting of alkylcatechols, alkoxyphenols, benzoquinones, phenothiazines, and phthalates; and the acid scavenger being at least one member selected from the group consisting of aliphatic alcohols, polyhydric alcohols, amines, terpenes, alkyl epoxides, and alkenyl tolyls; wherein the stabilizer container is disposed between the evaporator and the expansion mechanism in case of cooling, or between the evaporator and the expansion mechanism in case of heating, or between the evaporator and the expansion mechanism , between which the refrigerant flows in the circulation route as a refrigerant in a low-pressure gas-liquid mixing state. the optional antioxidant being at least one member selected from the group consisting of alkylcatechols, alkoxyphenols, benzoquinones, phenothiazines, and phthalates; and the acid scavenger being at least one member selected from the group consisting of aliphatic alcohols, polyhydric alcohols, amines, terpenes, alkyl epoxides, and alkenyl tolyls; wherein the stabilizer container is disposed between the evaporator and the expansion mechanism in case of cooling, or between the evaporator and the expansion mechanism in case of heating, or between the evaporator and the expansion mechanism , between which the refrigerant flows in the circulation route as a refrigerant in a low-pressure gas-liquid mixing state.
Shrink pipe shoe for easy to handle setting and reliable stabilising of the orientation of a shrink pipe that is connectable to a joint strip which is preferably internal in a construction j oint, comprising a. a panel , a, preferably tubular, receiving device is moulded onto the top of the panel , which device is provided for being received in the shrink pipe , characterised in that b. two ridges which are oriented in parallel with one another and are spaced apart from one another, forming a ridge interior , are moulded onto the bottom of the panel facing away from a top , which ridges are intended for receiving the joint strip or at least a part thereof, c. two strip-shaped crack guidance ridges having a mutually corresponding central longitudinal axis (M) are moulded onto the bottom of the panel and onto the opposing outsides of the ridges , d. the ridge interior is provided for receiving the joint strip or at least a part thereof, e. the ridges are provided for, e.g. close, connection, preferably thermal welding, to the joint strip in an end position. a. a panel , a, preferably tubular, receiving device is moulded onto the top of the panel , which device is provided for being received in the shrink pipe , characterised in that b. two ridges which are oriented in parallel with one another and are spaced apart from one another, forming a ridge interior , are moulded onto the bottom of the panel facing away from a top , which ridges are intended for receiving the joint strip or at least a part thereof, c. two strip-shaped crack guidance ridges having a mutually corresponding central longitudinal axis (M) are moulded onto the bottom of the panel and onto the opposing outsides of the ridges , d. the ridge interior is provided for receiving the joint strip or at least a part thereof, e. the ridges are provided for, e.g. close, connection, preferably thermal welding, to the joint strip in an end position.
A plate for use in a heat exchanger , the plate comprising: a first surface ; a second surface extending parallel to and spaced from the first surface ; first, second and third discrete flow passages passing through the plate from the first surface to the second surface , the second flow passage extending around the first flow passage and the third flow passage extending around the second flow passage ; a plurality of fins extending parallel to the first surface across the third flow passage and having a first fin surface extending parallel to the first surface of the plate and a second fin surface extending parallel to and spaced from the first fin surface ; and one or more pins protruding from the first fin surface of at least some of the fins , the pins extending away from the second fin surfaces , wherein a first distance (d 1 ) from the second fin surfaces to an end of the pins removed from the first fin surfaces is less than or equal to a second distance d 2 from the second surface of the plate to the first surface thereof. a first surface ; a second surface extending parallel to and spaced from the first surface ; first, second and third discrete flow passages passing through the plate from the first surface to the second surface , the second flow passage extending around the first flow passage and the third flow passage extending around the second flow passage ; a plurality of fins extending parallel to the first surface across the third flow passage and having a first fin surface extending parallel to the first surface of the plate and a second fin surface extending parallel to and spaced from the first fin surface ; and one or more pins protruding from the first fin surface of at least some of the fins , the pins extending away from the second fin surfaces , wherein a first distance (d 1 ) from the second fin surfaces to an end of the pins removed from the first fin surfaces is less than or equal to a second distance d 2 from the second surface of the plate to the first surface thereof.
A computer-implemented method for understanding and resolving references to visual elements in a visual context of a conversational computing system, the method comprising: identifying a plurality of visual elements available for user interaction in the visual context on a display; receiving speech input including one or more words spoken by a user; extracting lexical features from the speech input by computing, for each visual element of the plurality of visual elements, a lexical similarity between the speech input and text associated with a respective visual element of the plurality of visual elements and computing a probability for each lexical similarity; receiving, from a tracking component a gaze input ; determining , from the gaze input, a heat map representing a probabilistic model of objects the user is looking at in the visual context on the display, the objects including the plurality of visual elements; determining that a particular visual element of the plurality of visual elements is an intended visual element of the speech input using a combination of the computed probabilities for lexical similarities and the heat map; determining, by one or more processors, that the speech input comprises a command directed to the particular visual element; and causing an action associated with the particular visual element to be performed. identifying a plurality of visual elements available for user interaction in the visual context on a display; receiving speech input including one or more words spoken by a user; extracting lexical features from the speech input by computing, for each visual element of the plurality of visual elements, a lexical similarity between the speech input and text associated with a respective visual element of the plurality of visual elements and computing a probability for each lexical similarity; receiving, from a tracking component a gaze input ; determining , from the gaze input, a heat map representing a probabilistic model of objects the user is looking at in the visual context on the display, the objects including the plurality of visual elements; determining that a particular visual element of the plurality of visual elements is an intended visual element of the speech input using a combination of the computed probabilities for lexical similarities and the heat map; determining, by one or more processors, that the speech input comprises a command directed to the particular visual element; and causing an action associated with the particular visual element to be performed.