mhurhangee/patent-ind-claim-en huggingface dataset:
( Currently Amended ) An improved process for the preparation of fluvoxamine maleate of formula I, comprising the steps of: a) condensing the compound of formula II, with hydroxylamine hydrochloride in organic solvent selected from alcohol, ketone, nitrile, hydrocarbons or mixtures thereof, with improvement comprising the reaction is conducted in the presence of sodium carbonate granules at temperature 45-50°C to form a compound of formula III; b) isolating compound of formula III; c) treating compound of formula III with 2-chloroethylamine hydrochloride in the presence of base in solvent with improvement comprising the reaction is conducted at temperature 40-45°C to form compound of formula IV; d) extracting compound of formula IV with solvent to form an organic layer; e) treating organic layer of step d) with maleic acid; f) isolating crude fluvoxamine maleate of formula I; and g) optionally purifying fluvoxamine maleate of formula I a) condensing the compound of formula II, with hydroxylamine hydrochloride in organic solvent selected from alcohol, ketone, nitrile, hydrocarbons or mixtures thereof, with improvement comprising the reaction is conducted in the presence of sodium carbonate granules at temperature 45-50°C to form a compound of formula III; b) isolating compound of formula III; c) treating compound of formula III with 2-chloroethylamine hydrochloride in the presence of base in solvent with improvement comprising the reaction is conducted at temperature 40-45°C to form compound of formula IV; d) extracting compound of formula IV with solvent to form an organic layer; e) treating organic layer of step d) with maleic acid; f) isolating crude fluvoxamine maleate of formula I; and g) optionally purifying fluvoxamine maleate of formula I
Polymer blend for producing a packaging material with low gas permeability, characterized in that the polymer blend comprises polyvinyl alcohol (PVOH) and/or a PVOH copolymer as well as a further polymer, wherein - the mass-related mixing ratio lies in the range from 15 to 70 % w/w polyvinyl alcohol (PVOH) and/or a PVOH copolymer; and 30 to 85 % w/w of the further polymer, and - the further polymer is selected from the group consisting of polyethylene (PE), polypropylene (PP), and polystyrene (PS), or is a biodegradable polymer - the mass-related mixing ratio lies in the range from 15 to 70 % w/w polyvinyl alcohol (PVOH) and/or a PVOH copolymer; and 30 to 85 % w/w of the further polymer, and - the further polymer is selected from the group consisting of polyethylene (PE), polypropylene (PP), and polystyrene (PS), or is a biodegradable polymer
A photonic integrated circuit, PIC, configured for a three-dimensional, 3D. laser Doppler vibrometer, LDV, the PIC comprising: - a splitter to split a laser beam into a measurement signal and a reference signal; - a phase-amplitude modulator array coupled to a transmitting array to generate, from the measurement signal, n output signals to be directed to a single target location and to output the n output signals from substantially a single location, each output signal having a different direction and a different carrier frequency, n being a natural number greater than or equal to three; - a receiving array comprising m receiving antennas (123 1 , 123 2 , 123 3 ), each receiving antenna being configured to receive a reflection signal from a different receiving direction, each reflection signal being indicative of one or more of the output signals having been reflected at the single target location, m being a natural number greater than or equal to three; - for each receiving antenna, a mixer connected thereto to mix the reference signal with the received reflected signal; and - for each mixer, at least one photo-diode connected thereto to generate a photo-current signal from the mixed signal. - a splitter to split a laser beam into a measurement signal and a reference signal; - a phase-amplitude modulator array coupled to a transmitting array to generate, from the measurement signal, n output signals to be directed to a single target location and to output the n output signals from substantially a single location, each output signal having a different direction and a different carrier frequency, n being a natural number greater than or equal to three; - a receiving array comprising m receiving antennas (123 1 , 123 2 , 123 3 ), each receiving antenna being configured to receive a reflection signal from a different receiving direction, each reflection signal being indicative of one or more of the output signals having been reflected at the single target location, m being a natural number greater than or equal to three; - for each receiving antenna, a mixer connected thereto to mix the reference signal with the received reflected signal; and - for each mixer, at least one photo-diode connected thereto to generate a photo-current signal from the mixed signal.
A computer implemented method of creating a dimensional printing file by programmatically calculating a dimensional layer for application to a source image within said file, comprising: selecting said source image; a processor applying a copy of said source image to a dimensional printing channel, the dimensional printing channel corresponding to a channel of the source image, and with said dimensional printing channel calculating said dimensional layer for dimensional printing by: said processor applying a convolution filter to said source image to extract edges; said processor converting said filtered source image to gray scale; said processor inverting said gray scaled and filtered source image; and said processor performing a histogram adjustment of said inverted gray scaled and filtered source image; and said processor subsequently inserting back into said file said source image with said calculated dimensional printing layer in said dimensional printing channel, wherein the histogram adjustment stretches the histogram such as to limit the amount of clear dry ink used during dimensional printing. selecting said source image; a processor applying a copy of said source image to a dimensional printing channel, the dimensional printing channel corresponding to a channel of the source image, and with said dimensional printing channel calculating said dimensional layer for dimensional printing by: said processor applying a convolution filter to said source image to extract edges; said processor converting said filtered source image to gray scale; said processor inverting said gray scaled and filtered source image; and said processor performing a histogram adjustment of said inverted gray scaled and filtered source image; and said processor applying a convolution filter to said source image to extract edges; said processor converting said filtered source image to gray scale; said processor inverting said gray scaled and filtered source image; and said processor performing a histogram adjustment of said inverted gray scaled and filtered source image; and said processor subsequently inserting back into said file said source image with said calculated dimensional printing layer in said dimensional printing channel, wherein the histogram adjustment stretches the histogram such as to limit the amount of clear dry ink used during dimensional printing.
A method of creating an adeno-associated virus (AAV) virion comprising contacting cells, under conditions for formation of AAV virions, with a first nucleic acid sequence and a second nucleic acid sequence, wherein the AAV virion is formed from at least AAV8 viral protein 1 (VP1), and AAV2 viral protein 3 (VP3) viral structural proteins, wherein the first nucleic acid encodes VP1 from AAV8 serotype only but is not capable of expressing VP3, and the second nucleic acid sequence encodes VP3 from a AAV2 serotype only and further is not capable of expressing VP1, and wherein, the AAV virion comprises VP1 from AAV8 serotype only and VP3 from AAV2 serotype only, and wherein if viral protein 2 (VP2) is expressed, it is only from AAV8 serotype.
An alignment assembly comprising: a base ; a support leg extending from the base , the leg configured to support a portion of a turbine system structure; a first support leg portion disposed on a surface of the base and coupleable thereto; a second support leg portion angularly oriented relative to the first support leg portion and coupleable to the turbine system structure; and a jack assembly moveable on the surface of the base and configured to vertically and laterally adjust the turbine system structure, characterised in that it comprises at least one low friction plate disposed on the surface of the base to provide slideable adjustment of the jack assembly . a base ; a support leg extending from the base , the leg configured to support a portion of a turbine system structure; a first support leg portion disposed on a surface of the base and coupleable thereto; a second support leg portion angularly oriented relative to the first support leg portion and coupleable to the turbine system structure; and a jack assembly moveable on the surface of the base and configured to vertically and laterally adjust the turbine system structure, characterised in that it comprises at least one low friction plate disposed on the surface of the base to provide slideable adjustment of the jack assembly .
A pressure transmitter for measuring a pressure (P1; P2) of a process fluid in an industrial process, comprising: a pressure sensor having an output related to an applied pressure (P1; P2); measurement circuitry (18; 20) coupled to the pressure sensor configured to provide a transmitter output related to the applied pressure (P1; P2); a pressure coupling face having an opening (28; 30) therein arranged to transfer the applied pressure (P1; P2) to the pressure sensor ; and a pressure coupling flange having a flange face abutting the pressure coupling face configured to convey the process fluid to the opening (28; 30) of the pressure coupling face ; and wherein at least one of the pressure coupling face and the flange face is curved to protrude in a direction toward another of the pressure coupling face and the flange face such that, application of a mounting force (N) to mount the pressure coupling face to the pressure coupling flange causes the curved one of the pressure coupling face and the flange face to bend to conform to a shape of the other of the pressure coupling face and the flange face . a pressure sensor having an output related to an applied pressure (P1; P2); measurement circuitry (18; 20) coupled to the pressure sensor configured to provide a transmitter output related to the applied pressure (P1; P2); a pressure coupling face having an opening (28; 30) therein arranged to transfer the applied pressure (P1; P2) to the pressure sensor ; and a pressure coupling flange having a flange face abutting the pressure coupling face configured to convey the process fluid to the opening (28; 30) of the pressure coupling face ; and wherein at least one of the pressure coupling face and the flange face is curved to protrude in a direction toward another of the pressure coupling face and the flange face such that, application of a mounting force (N) to mount the pressure coupling face to the pressure coupling flange causes the curved one of the pressure coupling face and the flange face to bend to conform to a shape of the other of the pressure coupling face and the flange face .
A surveillance system for monitoring movement in a region of interest , said surveillance system including: a camera or a plurality of cameras having a field of view including a region of interest , and adapted to capture an image of the region of interest; wherein the camera or the plurality of cameras is configured to capture images, each image including at least two portions, said portions being captured at different apparent magnifications for at least a pair of corresponding zones within the region of interest in the field of view that are at different distances from the camera or the plurality of cameras, such that an object in a first position in a first zone will appear in an image as having substantially the same size that an image of the object would if the object were in a second position in a second zone, said first and second positions being at different distances from the camera or the plurality of cameras; a computer configured to process a time-sequential series of images of the field of view from the camera or the plurality of cameras where at least a portion of each processed image is analysed for detecting movement within the region of interest whereby an object's motion is tracked as it passes from one zone to another. a camera or a plurality of cameras having a field of view including a region of interest , and adapted to capture an image of the region of interest; wherein the camera or the plurality of cameras is configured to capture images, each image including at least two portions, said portions being captured at different apparent magnifications for at least a pair of corresponding zones within the region of interest in the field of view that are at different distances from the camera or the plurality of cameras, such that an object in a first position in a first zone will appear in an image as having substantially the same size that an image of the object would if the object were in a second position in a second zone, said first and second positions being at different distances from the camera or the plurality of cameras; a computer configured to process a time-sequential series of images of the field of view from the camera or the plurality of cameras where at least a portion of each processed image is analysed for detecting movement within the region of interest whereby an object's motion is tracked as it passes from one zone to another.
A cable feedthrough assembly for guiding at least one cable through an aperture in a vehicle body panel , the assembly comprising a first resiliently deformable elastomeric seal member and a second resiliently deformable elastomeric seal member for abutment with the first seal member, wherein the seal members define at least one cable passageway comprising a first through-hole in the first seal member and a corresponding second through-hole in the second seal member, characterized in the first seal member is configured for abutment with a vehicle body panel , the cable feedthrough assembly including a clamping member mountable to the vehicle body panel so as to clamp the second seal member to the first seal member and the first seal member to the body panel , wherein the first seal member has a first cable insertion slit extending from a peripheral edge of the first seal member to the first through-hole and the second seal member has a second cable insertion slit extending from a peripheral edge of the second seal member to the second through-hole , the first cable insertion slit and the second cable insertion slit being offset from one another, each of the first and second cable insertion slits being a narrow, cut-like, opening through the material of the seal member having a width smaller than the maximum diameter of its respective through-hole .
A method for sending multimedia content for display on a web page in a client (220; 310,320; 410,415) -server (205b; 305,335; 405) system in a network , the web page being rendered on a web browser provided on a client device, wherein the multimedia content comprises a plurality of image objects originating from a web server, the method comprising: in a first step, sending a first predetermined portion of each of the plurality of image objects from the server (205b; 305,335; 405) through the network , and after sending the first predetermined portion of each of the plurality of image objects, successively sending subsequent predetermined portions of each of the plurality of image objects, characterised in the first predetermined portion for at least one of the plurality of image objects being reconstructable to produce an image at a lower quality level than a quality of the image reconstructable from the complete image object; and the subsequent predetermined portions for the at least one of the plurality of image objects comprising image refinement data at a progressively higher quality level. in a first step, sending a first predetermined portion of each of the plurality of image objects from the server (205b; 305,335; 405) through the network , and after sending the first predetermined portion of each of the plurality of image objects, successively sending subsequent predetermined portions of each of the plurality of image objects, characterised in the first predetermined portion for at least one of the plurality of image objects being reconstructable to produce an image at a lower quality level than a quality of the image reconstructable from the complete image object; and the subsequent predetermined portions for the at least one of the plurality of image objects comprising image refinement data at a progressively higher quality level.
A method for performing cell management in a heterogeneous network deployment scenario in which a macro Macro eNB provides macro coverage, and a local eNB provides hotspot coverage within a range of the macro coverage, said method comprising: receiving , by a User Equipment UE, a notification of managing cells controlled by the local eNB from the Macro eNB or the local eNB; wherein the UE aggregates resources of the Macro eNB and the local eNB, and a Radio Resource Control connection of the UE is maintained under the Macro eNB; wherein the cells controlled by the local eNB comprise a primary cell and a secondary cell for carrier aggregation by the UE; and managing , by the UE, cells controlled by the local eNB according to the notification; wherein managing the cells controlled by the local eNB comprises at least one of the following: selecting or changing the primary cell controlled by the local eNB, adding or deleting the secondary cell controlled by the local eNB, or modifying configuration information of the secondary cell controlled by the local eNB. receiving , by a User Equipment UE, a notification of managing cells controlled by the local eNB from the Macro eNB or the local eNB; wherein the UE aggregates resources of the Macro eNB and the local eNB, and a Radio Resource Control connection of the UE is maintained under the Macro eNB; wherein the cells controlled by the local eNB comprise a primary cell and a secondary cell for carrier aggregation by the UE; and managing , by the UE, cells controlled by the local eNB according to the notification; wherein managing the cells controlled by the local eNB comprises at least one of the following: selecting or changing the primary cell controlled by the local eNB, adding or deleting the secondary cell controlled by the local eNB, or modifying configuration information of the secondary cell controlled by the local eNB.
Capsule for preparing beverages, comprising: - an essentially closed housing which is at least partially filled with a substance to be extracted and/or dissolved, such as ground coffee, for preparing a beverage, wherein the housing is essentially closed, wherein the housing is defined at least by a peripheral wall , an end side connected to the peripheral wall , and a laterally protruding engaging edge connected to the peripheral wall at a distance from the end side in order to allow the capsule to be clamped into a capsule holder of a device for preparing beverages; and - at least one essentially closed closing element connected to the laterally protruding engaging edge for sealing the substance into the capsule in order to preserve it, characterized in that at least a part of the closing element is composed of a laminated film comprising a plurality of polymer layers (3, 5, 6, 13a, 13c, 13d, 13f, 21a-21f, 40a, 40b, 40c), which film comprises at least one polymer oxygen barrier layer , which barrier layer is essentially impermeable to oxygen, and which film comprises at least one polymer carrier layer connected to the oxygen barrier layer , wherein at least one carrier layer is provided with at least one weakened area , and wherein the film comprises at least one shielding layer connected to a side of the oxygen barrier layer facing away from the substance, wherein the shielding layer is closed, and wherein the shielding layer preferably forms a moisture barrier layer. - an essentially closed housing which is at least partially filled with a substance to be extracted and/or dissolved, such as ground coffee, for preparing a beverage, wherein the housing is essentially closed, wherein the housing is defined at least by a peripheral wall , an end side connected to the peripheral wall , and a laterally protruding engaging edge connected to the peripheral wall at a distance from the end side in order to allow the capsule to be clamped into a capsule holder of a device for preparing beverages; and - at least one essentially closed closing element connected to the laterally protruding engaging edge for sealing the substance into the capsule in order to preserve it,
A composition comprising a single-chain guide RNA (sgRNA) and a Streptococcus pyogenes Cas9 protein, wherein the sgRNA and the Cas9 protein are present in a molar ratio ranging from 29 : 14.0 to 29 : 1.4.
Tyre with a radial carcass reinforcement, made up of at least one layer of metal reinforcing elements inserted between two skim layers of elastomer compound containing a reinforcing filler made up of at least carbon black, the said tyre comprising a crown reinforcement, itself capped radially by a tread, the said tread being connected to two beads by two sidewalls, the said tyre forming an internal cavity intended to accept inflation air, characterized in that the tensile elastic modulus at 10% elongation of at least the skim layer closest to the internal cavity of at least the carcass reinforcement layer closest to the internal cavity is less than 8.5 MPa and in that at least the said skim layer closest to the internal cavity of at least the carcass reinforcement layer closest to the internal cavity has a macrodispersion value Z greater than 85, the value Z being measured, according to the method described by S. Otto et al. in Kautschuk Gummi Kunststoffe, 58 Jahrgang, NR 7-8/2005, in accordance with standard ISO 11345.