mhurhangee/patent-ind-claim-en huggingface dataset:
Ignition system for an internal combustion engine having a cylinder head and at least one combustion chamber , said ignition system comprising: a housing defined in the cylinder head of the internal combustion engine , said housing defining a pre-chamber ; an ignition device supported in said housing and having an igniter portion that substantially faces said pre-chamber ; an injector supported in said housing and having a nozzle that substantially faces said pre-chamber ; said pre-chamber defining a proximal portion and a pre-chamber nozzle disposed spaced from said proximal portion of said pre-chamber , said pre-chamber nozzle including a plurality of orifices disposed spaced from one another and providing fluid communication between said pre-chamber and the combustion chamber , and said pre-chamber defining a predetermined volume ; said igniter portion of said ignition device and said nozzle of said injector being operatively supported in the proximal portion of the pre-chamber such that said injector delivers a predetermined quantity of fuel into said pre-chamber , said igniter portion ignites the fuel in said pre-chamber such that the ignited fuel is forced through said orifices of said pre-chamber nozzle and extinguished, but dispersed through the combustion chamber so as to ignite the main fuel charge therein, characterised in that the orifices have a diameter in a range between 0.7 mm and 2.0 mm, and the ratio of the orifices diameter to the pre-chamber volume is in a range between 0.048 1/cm 2 and 0.067 1/cm 2 . therein. a housing defined in the cylinder head of the internal combustion engine , said housing defining a pre-chamber ; an ignition device supported in said housing and having an igniter portion that substantially faces said pre-chamber ; an injector supported in said housing and having a nozzle that substantially faces said pre-chamber ; said pre-chamber defining a proximal portion and a pre-chamber nozzle disposed spaced from said proximal portion of said pre-chamber , said pre-chamber nozzle including a plurality of orifices disposed spaced from one another and providing fluid communication between said pre-chamber and the combustion chamber , and said pre-chamber defining a predetermined volume ; said igniter portion of said ignition device and said nozzle of said injector being operatively supported in the proximal portion of the pre-chamber such that said injector delivers a predetermined quantity of fuel into said pre-chamber , said igniter portion ignites the fuel in said pre-chamber such that the ignited fuel is forced through said orifices of said pre-chamber nozzle and extinguished, but dispersed through the combustion chamber so as to ignite the main fuel charge therein, characterised in that the orifices have a diameter in a range between 0.7 mm and 2.0 mm, and the ratio of the orifices diameter to the pre-chamber volume is in a range between 0.048 1/cm 2 and 0.067 1/cm 2 . therein.
A compound having the formula: or a pharmaceutically acceptable salt thereof, wherein the subscript n is 1 or 2; each R 1 is a member selected from the group consisting of fluoro, chloro, optionally substituted C 1 -C 4 alkyl, optionally substituted C 1 -C 4 haloalkyl, optionally substituted C 1 -C 4 alkoxy, optionally substituted C 1 -C 4 haloalkoxy, and optionally substituted C 2 -C 4 alkynyl; wherein at least one R 1 is fluoro; and one of R 2a and R 2b is fluoro and the other of R 2a and R 2b is H. or a pharmaceutically acceptable salt thereof, wherein the subscript n is 1 or 2; each R 1 is a member selected from the group consisting of fluoro, chloro, optionally substituted C 1 -C 4 alkyl, optionally substituted C 1 -C 4 haloalkyl, optionally substituted C 1 -C 4 alkoxy, optionally substituted C 1 -C 4 haloalkoxy, and optionally substituted C 2 -C 4 alkynyl; wherein at least one R 1 is fluoro; and one of R 2a and R 2b is fluoro and the other of R 2a and R 2b is H.
A device configured as a woven, self-expanding stent for insertion into an anatomical structure, the device comprising: a plurality of strands woven together to form a stent body, each of said plurality of strands having two strand end portions ; a respective coupling structure coupled to each pair of strand end portions such that the number of coupling structures corresponds to the number of strands, the pair of strand end portions being aligned end-to-end and comprising strand end portions from a same strand or two different strands; wherein the pair of strand end portions includes nickel and titanium, and the coupling structure is not a strand of the device, wherein the coupling structure is secured to a first strand end portion of the pair of strand end portions by a first weld that forms a first welded region , the coupling structure is secured to a second strand end portion of the pair of strand end portions by a second weld that forms a second welded region , and the first and second welded regions are not directly connected to each other along a longitudinal axis of the coupling structure by another welded region, and wherein the coupling structure is positioned beneath a strand of the device such that the strand is positioned radially outward from the coupling structure . a plurality of strands woven together to form a stent body, each of said plurality of strands having two strand end portions ; a respective coupling structure coupled to each pair of strand end portions such that the number of coupling structures corresponds to the number of strands, the pair of strand end portions being aligned end-to-end and comprising strand end portions from a same strand or two different strands; wherein the pair of strand end portions includes nickel and titanium, and the coupling structure is not a strand of the device, wherein the coupling structure is secured to a first strand end portion of the pair of strand end portions by a first weld that forms a first welded region , the coupling structure is secured to a second strand end portion of the pair of strand end portions by a second weld that forms a second welded region , and the first and second welded regions are not directly connected to each other along a longitudinal axis of the coupling structure by another welded region, and wherein the coupling structure is positioned beneath a strand of the device such that the strand is positioned radially outward from the coupling structure .
A computer implemented method of designing a dental restoration for a patient, wherein the method comprises: - providing one or more 2D images showing the patient's teeth before preparing the teeth, where at least one 2D image comprises at least one facial feature wherein the facial feature(s) are present in an image of the patient and wherein the facial features comprise(s) the lips of the patient; - cutting out the part of the 2D image which is inside the edge of the lips; - providing a 3D virtual model of at least part of the patient's oral cavity; - arranging the 2D image and the 3D virtual model in the virtual 3D space as separate representations at a distance between each other so that the 2D image and the 3D virtual model are aligned when viewed from a front viewpoint; - scaling the one or more 2D digital image and the 3D virtual model to show at least part of the teeth in the same size; and - digitally designing a restoration on the 3D virtual model. - providing one or more 2D images showing the patient's teeth before preparing the teeth, where at least one 2D image comprises at least one facial feature wherein the facial feature(s) are present in an image of the patient and wherein the facial features comprise(s) the lips of the patient; - cutting out the part of the 2D image which is inside the edge of the lips; - providing a 3D virtual model of at least part of the patient's oral cavity; - arranging the 2D image and the 3D virtual model in the virtual 3D space as separate representations at a distance between each other so that the 2D image and the 3D virtual model are aligned when viewed from a front viewpoint; - scaling the one or more 2D digital image and the 3D virtual model to show at least part of the teeth in the same size; and - digitally designing a restoration on the 3D virtual model.
An intracardiac ventricular pacemaker , comprising: a pulse generator configured to generate and deliver a pacing pulse to a ventricle of a patient's heart via electrodes coupled to the pacemaker; a motion sensor configured to produce an electrical signal correlated to movement of blood within the ventricle; and a control circuit comprising an atrial event detector circuit coupled to the motion sensor and a pace timing circuit coupled to the pulse generator; wherein the atrial event detector circuit is configured to detect an atrial mechanical event from the motion sensor signal and pass an atrial event signal to the pace timing circuit in response to detecting the atrial mechanical event, the pace timing circuit configured to schedule the pacing pulse by starting a pacing interval in response to receiving the atrial event signal, the pulse generator configured to deliver the scheduled pacing pulse to a ventricle of the patient's heart in response to the pacing interval expiring. a pulse generator configured to generate and deliver a pacing pulse to a ventricle of a patient's heart via electrodes coupled to the pacemaker; a motion sensor configured to produce an electrical signal correlated to movement of blood within the ventricle; and a control circuit comprising an atrial event detector circuit coupled to the motion sensor and a pace timing circuit coupled to the pulse generator; wherein the atrial event detector circuit is configured to detect an atrial mechanical event from the motion sensor signal and pass an atrial event signal to the pace timing circuit in response to detecting the atrial mechanical event, the pace timing circuit configured to schedule the pacing pulse by starting a pacing interval in response to receiving the atrial event signal, the pulse generator configured to deliver the scheduled pacing pulse to a ventricle of the patient's heart in response to the pacing interval expiring.
Method for installing an offshore structure at an offshore site having a sea bottom and a water depth defining a sea level ; the offshore structure including a seabed fixation structure, a transition piece and a superstructure; the method comprising - installing the seabed fixation structure to the sea bottom, such that the seabed fixation structure at least partly extends above the sea bottom; - positioning the transition piece on the seabed fixation structure, wherein at least an upper side of the transition piece is above the sea level; - positioning the superstructure on the transition piece such that the superstructure is extending above the sea level; wherein at least one of the connection between the transition piece and the seabed fixation structure and of the connection between the transition piece and the superstructure is provided as an in-line connection comprising at least two sets of conical rings (38, 39; 40, 41) engaging each other; characterized in that the at least one in-line connection is at least partly below the sea level . - installing the seabed fixation structure to the sea bottom, such that the seabed fixation structure at least partly extends above the sea bottom; - positioning the transition piece on the seabed fixation structure, wherein at least an upper side of the transition piece is above the sea level; - positioning the superstructure on the transition piece such that the superstructure is extending above the sea level;
A thrombus extraction device for removal of a vascular thrombus from a blood vessel of a patient, the thrombus extraction device comprising: a catheter having a proximal end and a distal end , an outer shaft defining a first lumen , an intermediate shaft defining a second lumen , and an inner shaft , wherein the intermediate shaft is coaxial the first lumen (802 and the inner shaft is coaxial the second lumen ; a proximal self-expanding coring element formed of a unitary fenestrated structure having a proximal end and a distal end and configured to core and separate a portion of the vascular thrombus from the blood vessel, wherein the proximal end of the self-expanding coring element is coupled to the distal end of the intermediate shaft ; and a distal expandable cylindrical portion formed of a braided filament mesh structure having a proximal end and a distal end and configured to capture the vascular thrombus portion, wherein the proximal end of the mesh structure is attached to the distal end of the self-expanding coring element, and wherein the distal end of the mesh structure is coupled to the distal end of the inner shaft, wherein expansion of the mesh structure and self-expanding coring element varies based on a position of the intermediate shaft relative the inner shaft of the catheter. a catheter having a proximal end and a distal end , an outer shaft defining a first lumen , an intermediate shaft defining a second lumen , and an inner shaft , wherein the intermediate shaft is coaxial the first lumen (802 and the inner shaft is coaxial the second lumen ; a proximal self-expanding coring element formed of a unitary fenestrated structure having a proximal end and a distal end and configured to core and separate a portion of the vascular thrombus from the blood vessel, wherein the proximal end of the self-expanding coring element is coupled to the distal end of the intermediate shaft ; and a distal expandable cylindrical portion formed of a braided filament mesh structure having a proximal end and a distal end and configured to capture the vascular thrombus portion, wherein the proximal end of the mesh structure is attached to the distal end of the self-expanding coring element, and wherein the distal end of the mesh structure is coupled to the distal end of the inner shaft, wherein expansion of the mesh structure and self-expanding coring element varies based on a position of the intermediate shaft relative the inner shaft of the catheter.
Process to treat siliceous non-sulfidic ores with a collector composition that comprises a phosphate compound of the formula I wherein R is linear or branched, saturated or unsaturated hydrocarbon group containing 8 to 24 carbon atoms, A is an alkylene oxide unit; Y is H, Na, K or an ammonium or alkylated ammonium, n is 1 - 3, p is 0 - 25, X is chosen from the same groups as R-Ap or Y, or wherein R is linear or branched, saturated or unsaturated hydrocarbon group that contains 1 to 12 carbon atoms and at least one unit A is present that is a propylene oxide unit.
A construction system for wall cladding, comprising a series of uprights and a series of cross-members intended to be supported between two uprights that are not aligned vertically, wherein - the cross-members are elongated and have two opposing terminals made of an elastically deformable material and with at least two bends, and - the uprights are equipped with anchor means in which the terminals of the cross-members can be secured by restoring force, said anchor means, for this purpose, comprising, for each terminal , at least two entry parts (A, B), in the form of slots or openings, spatially arranged in relation to the at least two bends (a, b) of the terminal, each one of the at least two bends being able to be inserted simultaneously into one of these entry parts, first requiring that said terminal , said upright or both the terminal and the upright, be elastically deformed so that said bends are pressed tightly against said entry parts through elastic reaction, characterized in that the cross-members are made of one piece and the opposing terminals are filiform or shaped to generate elastic force. - the cross-members are elongated and have two opposing terminals made of an elastically deformable material and with at least two bends, and - the uprights are equipped with anchor means in which the terminals of the cross-members can be secured by restoring force, said anchor means, for this purpose, comprising, for each terminal , at least two entry parts (A, B), in the form of slots or openings, spatially arranged in relation to the at least two bends (a, b) of the terminal, each one of the at least two bends being able to be inserted simultaneously into one of these entry parts, first requiring that said terminal , said upright or both the terminal and the upright, be elastically deformed so that said bends are pressed tightly against said entry parts through elastic reaction, characterized in that the cross-members are made of one piece and the opposing terminals are filiform or shaped to generate elastic force.
A fastening bracket for fastening studs of an insulating facade mountable in front of an external wall of a building, having an abutting leg placeable against the external wall of the building and a fastening leg placeable against the stud and being provided with a trapezoidal portion characterized in that above the shorter one of the parallel sides of the trapezoidal portion on the side of the trapezoidal portion opposite the abutment leg a rectangular portion is provided, the trapezoidal portion being formed by an isosceles trapezoid.
An antibody construct comprising a first domain which binds to BCMA, a second domain which binds to CD3 and a third Fc-based domain which extends the half-life of the antibody construct, for use in the treatment or amelioration of a BCMA positive neoplasm in a human subject, wherein the antibody construct is administered at a minimum dose of 800 μg/day in at least one cycle, wherein one cycle comprises at least three individual administrations of the antibody construct, wherein the antibody construct is administered during the first cycle on day 1 and in one or two dose steps.
A measurement apparatus capable of measuring particles in a fluid, comprising: a flow path device including a first flow path with translucency, configured to allow a first fluid including the particles to pass through, and a second flow path with translucency, configured to allow a second fluid which does not include the particles to pass through; an optical sensor that faces the flow path device , and is configured to irradiate each of the first flow path and the second flow path with light, and to receive light passing through each of the first flow path and the second flow path ; and a controller configured to estimate the number of particles by comparing an intensity of light passing through the first flow path and an intensity of light passing through the second flow path obtained based on an output of the optical sensor , wherein the flow path device includes a non-reflection member which is configured to not reflect light emitted from the optical sensor and to block disturbance light entering the first flow path and the second flow path from an opposite side of the optical sensor , and the non-reflection member is disposed in a region overlapping the first flow path and the second flow path on the opposite side of the optical sensor . a flow path device including a first flow path with translucency, configured to allow a first fluid including the particles to pass through, and a second flow path with translucency, configured to allow a second fluid which does not include the particles to pass through; an optical sensor that faces the flow path device , and is configured to irradiate each of the first flow path and the second flow path with light, and to receive light passing through each of the first flow path and the second flow path ; and a controller configured to estimate the number of particles by comparing an intensity of light passing through the first flow path and an intensity of light passing through the second flow path obtained based on an output of the optical sensor , wherein the flow path device includes a non-reflection member which is configured to not reflect light emitted from the optical sensor and to block disturbance light entering the first flow path and the second flow path from an opposite side of the optical sensor , and the non-reflection member is disposed in a region overlapping the first flow path and the second flow path on the opposite side of the optical sensor .
A microfluidic radiopharmaceutical synthesis system comprising a reaction vessel adapted to receive a radioisotope and at least one reagent, said reaction vessel being in heat-transfer communication with a heat source, the heat source configured to reach a temperature sufficient to remove heavy water, whereby when said radioisotope and said at least one reagent are mixed in said reaction vessel and heat is applied to said reaction vessel from said heat source, a radiopharmaceutical solution is synthesized; a solid-phase extraction column adapted to purify said radiopharmaceutical solution; a filter adapted to sterilize said radiopharmaceutical solution; and sample vessels adapted to receive said radiopharmaceutical solution following its passage through said solid-phase extraction column and said filter, wherein said system is scaled to produce per run a quantity of purified radiopharmaceutical solution approximately equal to, but no less than, one unit dose of radiopharmaceutical, wherein the system comprises a chemical production module (CPM) with a dose synthesis card; a sample card, which contains a number of sample vessels adapted to receive multiple aliquots of said purified radiopharmaceutical solution; and a quality control module (QCM) with a number of test vessels for testing following said purified radiopharmaceutical solution's passage through said solid-phase extraction column and said filter, wherein the quality control module (QCM) is configured such that the sample card after separation from the dose synthesis card is insertable in the quality control module (QCM), wherein said reaction vessel, said solid-phase extraction column, and said filter are incorporated into a disposable card, said card being discarded after one run, characterized in that , the system is configured such that each dose is produced in a separate run, such that the quality control tests are performed for every dose that is produced.
A falling film evaporator for reducing a liquid content of a dairy product (DP), the evaporator comprising a housing having an inlet and an outlet for passing a heating media (H) through the housing , a number of heat transfer tubes that are vertically arranged inside the housing such that the heating media (H) can flow over outer surfaces of the heat transfer tubes , each heat transfer tube of the heat transfer tubes comprising an upper inlet and a lower outlet for passing the dairy product over an inner surface of the heat transfer tube , characterised in that each heat transfer tube comprises corrugations that extend along the length of the heat transfer tube . a housing having an inlet and an outlet for passing a heating media (H) through the housing , a number of heat transfer tubes that are vertically arranged inside the housing such that the heating media (H) can flow over outer surfaces of the heat transfer tubes , each heat transfer tube of the heat transfer tubes comprising an upper inlet and a lower outlet for passing the dairy product over an inner surface of the heat transfer tube , characterised in that each heat transfer tube comprises corrugations that extend along the length of the heat transfer tube .