An ocular injection device, comprising: a housing defining an inner volume , a proximal end portion of the housing configured to be coupled to a medicament container , a distal end portion of the housing including a hub surface , the hub surface configured to contact a target surface of a target tissue; an adjustment member disposed within the inner volume such that the inner volume is separated into a first chamber and a second chamber , the first chamber in fluid communication with the medicament container when the proximal end portion of the housing is coupled to the medicament container , the adjustment member configured to transition within the inner volume between a first configuration and a second configuration; and a puncture member coupled to the adjustment member , a proximal end portion of the puncture member in fluid communication with the first chamber such that a substance can be conveyed from the medicament container through the puncture member via the first chamber , a distal tip of the puncture member extending from the hub surface by a first distance when the adjustment member is in the first configuration, the distal tip of the puncture member extending from the hub surface by a second distance when the adjustment member is in the second configuration, the second distance greater than the first distance, wherein: the adjustment member includes a seal member in sliding contact with an inner surface of the housing, the seal member fluidically isolating the first chamber from the second chamber; and the adjustment member is configured to move from a first position to a second position when the adjustment member transitions within the inner volume from the first configuration towards the second configuration. a housing defining an inner volume , a proximal end portion of the housing configured to be coupled to a medicament container , a distal end portion of the housing including a hub surface , the hub surface configured to contact a target surface of a target tissue; an adjustment member disposed within the inner volume such that the inner volume is separated into a first chamber and a second chamber , the first chamber in fluid communication with the medicament container when the proximal end portion of the housing is coupled to the medicament container , the adjustment member configured to transition within the inner volume between a first configuration and a second configuration; and a puncture member coupled to the adjustment member , a proximal end portion of the puncture member in fluid communication with the first chamber such that a substance can be conveyed from the medicament container through the puncture member via the first chamber , a distal tip of the puncture member extending from the hub surface by a first distance when the adjustment member is in the first configuration, the distal tip of the puncture member extending from the hub surface by a second distance when the adjustment member is in the second configuration, the second distance greater than the first distance, wherein: the adjustment member includes a seal member in sliding contact with an inner surface of the housing, the seal member fluidically isolating the first chamber from the second chamber; and the adjustment member is configured to move from a first position to a second position when the adjustment member transitions within the inner volume from the first configuration towards the second configuration. the adjustment member includes a seal member in sliding contact with an inner surface of the housing, the seal member fluidically isolating the first chamber from the second chamber; and the adjustment member is configured to move from a first position to a second position when the adjustment member transitions within the inner volume from the first configuration towards the second configuration. <EOS>