mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of formula (I) or a pharmaceutically acceptable salt thereof for use in treating irritable bowel syndrome or inflammatory bowel disease, wherein W, X, Y and Z each independently represent N, NH or CH, with the proviso that W, X, Y and Z do not each simultaneously represent a moiety CH; m is 0, 1, 2 or 3; each R 1 independently represents halogen, cyano, C 1 -C 6 alkoxy, C 3 -C 6 cycloalkyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylcarbonyl, or C 1 -C 6 alkyl optionally substituted by carboxyl or C 1 -C 6 alkoxycarbonyl; n is 0, 1, 2, 3 or 4; each R 2 independently represents halogen, cyano, carboxyl, hydroxyl, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 hydroxyalkyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkoxyC 1 -C 6 alkyl or a 5- to 9-membered heterocyclic ring system; R 6 represents a hydrogen or halogen atom or a cyano or C 1 -C 6 alkoxycarbonyl group; R 4 represents a 6- to 10-membered aromatic or heteroaromatic ring system, the ring system itself being optionally substituted by at least one substituent selected from halogen, hydroxyl, cyano, oxo (=O), C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 hydroxyalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulphinyl, C 1 -C 6 alkylsulphonyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkylcarbonyloxy, C 1 -C 6 alkoxycarbonyl, amino (-NH 2 ), -CON(R 9 ) 2 , C 1 -C 6 alkylamino, di-(C 1 -C 6 alkyl)amino, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyloxy or C 3 -C 6 cycloalkylmethyl; and each R 9 independently represents a hydrogen atom or a C 1 -C 6 alkyl group. W, X, Y and Z each independently represent N, NH or CH, with the proviso that W, X, Y and Z do not each simultaneously represent a moiety CH; m is 0, 1, 2 or 3; each R 1 independently represents halogen, cyano, C 1 -C 6 alkoxy, C 3 -C 6 cycloalkyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 haloalkyl, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylcarbonyl, or C 1 -C 6 alkyl optionally substituted by carboxyl or C 1 -C 6 alkoxycarbonyl; n is 0, 1, 2, 3 or 4; each R 2 independently represents halogen, cyano, carboxyl, hydroxyl, C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, C 1 -C 6 hydroxyalkyl, C 1 -C 6 alkoxycarbonyl, C 1 -C 6 alkoxyC 1 -C 6 alkyl or a 5- to 9-membered heterocyclic ring system; R 6 represents a hydrogen or halogen atom or a cyano or C 1 -C 6 alkoxycarbonyl group; R 4 represents a 6- to 10-membered aromatic or heteroaromatic ring system, the ring system itself being optionally substituted by at least one substituent selected from halogen, hydroxyl, cyano, oxo (=O), C 1 -C 6 alkyl, C 2 -C 6 alkenyl, C 2 -C 6 alkynyl, C 1 -C 6 haloalkyl, C 1 -C 6 hydroxyalkyl, C 1 -C 6 alkoxy, C 1 -C 6 haloalkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulphinyl, C 1 -C 6 alkylsulphonyl, C 1 -C 6 alkylcarbonyl, C 1 -C 6 alkylcarbonyloxy, C 1 -C 6 alkoxycarbonyl, amino (-NH 2 ), -CON(R 9 ) 2 , C 1 -C 6 alkylamino, di-(C 1 -C 6 alkyl)amino, C 3 -C 6 cycloalkyl, C 3 -C 6 cycloalkyloxy or C 3 -C 6 cycloalkylmethyl; and each R 9 independently represents a hydrogen atom or a C 1 -C 6 alkyl group.
Air bearing , in particular for a bearing unit of a compressor , comprising an outer ring which surrounds a central opening for accommodating a shaft , a spring foil which is arranged in the opening and is elastically deformable, and a top foil which is arranged in the opening , wherein the spring foil is arranged between the outer ring and the top foil , wherein the spring foil has a main body which is formed in one piece, wherein the spring foil has first material regions with a first spring stiffness and second material regions with a second spring stiffness, wherein each of the first material regions is arranged offset from each of the second material regions in a circumferential direction (U) of the opening , and wherein the first spring stiffness is greater than the second spring stiffness, wherein the second material regions comprise narrowing points in which a wall thickness of the main body is reduced, characterized in that the first material regions comprise beads which are stamped outwards from the main body .
A curable composition comprising 100 parts by mass of a flexible epoxy resin (A), 1 to 150 parts by mass of polymer fine particles (B), and 1 to 200 parts by mass of an epoxy curing agent (C), wherein a cured product obtained by curing a composition containing the flexible epoxy resin (A) has a type A durometer hardness value determined as defined in the description, of 1 to 95, the flexible epoxy resin (A) has an epoxy equivalent of from 350 to 4000 g/eq, the polymer fine particles have a core-shell structure and at least two layers of a core layer and a shell layer, the core layer of the polymer fine particles (B) has a glass transition temperature of more than 0 °C as calculated by the following numerical formula , the polymer fine particles have a volume average particle diameter (Mv) of 10 to 2000 nm, as measured by the method given in the present description, a cured product obtained by curing the curable composition has a type A durometer hardness of 5 to 95 at 23 °C as measured by JIS K6253-3, 1 / Tg = Σ M i / Tg i wherein M i represents a mass fraction of a monomer unit i selected from butadiene unit and a non-crosslinking monomer unit constituting the core layer of the polymer fine particles (B), and Tg i represents a glass transition temperature (K) of a homopolymer composed of the monomer unit i, where the values of Tg i are determined as described in the present description.
A measurement method for measuring the temperature of water, the method being performed at least in part in a meter and comprising the steps of: ▪ causing an emitter transducer of the meter to emit an ultrasonic measurement signal , and acquiring an electrical measurement signal (Sm) produced by a receiver transducer of the meter when it receives the ultrasonic measurement signal after the ultrasonic measurement signal has travelled along a path of defined length (L) in the water; characterized in that the method comprises the steps of : ▪ measuring a speed of the ultrasonic measurement signal in the water; ▪ measuring a level of the electrical measurement signal (Sm); ▪ using the level of the electrical measurement signal to determine whether the temperature of the water is less than or greater than an inflection temperature corresponding to a point of inflection in a curve plotting the speed of sound in water as a function of the temperature of the water; ▪ estimating the temperature of the water from the speed of the ultrasonic measurement signal by using a first formula if the temperature of the water is less than the inflection temperature, and by using a second formula if the temperature of the water is greater than the inflection temperature. ▪ causing an emitter transducer of the meter to emit an ultrasonic measurement signal , and acquiring an electrical measurement signal (Sm) produced by a receiver transducer of the meter when it receives the ultrasonic measurement signal after the ultrasonic measurement signal has travelled along a path of defined length (L) in the water; characterized in that the method comprises the steps of : ▪ measuring a speed of the ultrasonic measurement signal in the water; ▪ measuring a level of the electrical measurement signal (Sm); ▪ using the level of the electrical measurement signal to determine whether the temperature of the water is less than or greater than an inflection temperature corresponding to a point of inflection in a curve plotting the speed of sound in water as a function of the temperature of the water; ▪ estimating the temperature of the water from the speed of the ultrasonic measurement signal by using a first formula if the temperature of the water is less than the inflection temperature, and by using a second formula if the temperature of the water is greater than the inflection temperature. ▪ measuring a speed of the ultrasonic measurement signal in the water; ▪ measuring a level of the electrical measurement signal (Sm); ▪ using the level of the electrical measurement signal to determine whether the temperature of the water is less than or greater than an inflection temperature corresponding to a point of inflection in a curve plotting the speed of sound in water as a function of the temperature of the water; ▪ estimating the temperature of the water from the speed of the ultrasonic measurement signal by using a first formula if the temperature of the water is less than the inflection temperature, and by using a second formula if the temperature of the water is greater than the inflection temperature.
A consumer's facility equipment connected to a first network provided in a power consumer's facility, comprising: a receiver configured to receive a message of a process instruction for the equipment, through the first network from a control apparatus communicable with the first network and a second network other than the first network, wherein the message complies with a predetermined communication protocol, and the message includes an information element indicating whether or not the process instruction for the equipment is made through the second network, and a controller configured to execute a first process according to the message when the information element indicates that the process instruction is made through the second network, and execute a second process different from the first process according to the message when the information element indicates that the process instruction is not made through the second network. a receiver configured to receive a message of a process instruction for the equipment, through the first network from a control apparatus communicable with the first network and a second network other than the first network, wherein the message complies with a predetermined communication protocol, and the message includes an information element indicating whether or not the process instruction for the equipment is made through the second network, and a controller configured to execute a first process according to the message when the information element indicates that the process instruction is made through the second network, and execute a second process different from the first process according to the message when the information element indicates that the process instruction is not made through the second network. execute a first process according to the message when the information element indicates that the process instruction is made through the second network, and execute a second process different from the first process according to the message when the information element indicates that the process instruction is not made through the second network.
A composite functional cutting tool coating for cutting titanium alloys, characterized by comprising a bottom coating and a top coating, wherein the bottom coating consists of the following elements in atomic percentage: 10-40at.% of titanium, 5-20at.% of aluminum, 2-18at.% of tantalum and 40.16-55at.% of nitrogen, and the thickness is 1 to 4 micrometers ; and the top coating consists of the following elements in atomic percentage: 50-78.02at.% of oxygen, 8-35at.% of tantalum and the thickness is 50-1,500 nm.
Sputtering target consisting of a NiSi alloy consisting of Ni, from 2 to 8 weight% Si, optionally dopant elements in an amount of 1000 ppm or less, and the remainder being unavoidable impurities, characterized in that the NiSi alloy has an average grain size of 150 to 400 μm and a grain size variation of lower than 30% both measured according to the specification.
A method of detecting particulate radiation using a semiconductor based pixelated detector, the detector pixels having a detector pixel size, the detector sensitive to the particulate radiation, each particle of the particulate radiation causing a multitude of electron/hole pairs in the semiconductor material of the detector, the multitude of electron/hole pairs having a centroid and a centroid extent, the extent of the centroid extent larger than the detector pixel size, the method comprising: • A step of intercepting a particle of the particulate radiation, • A step of estimating the number of electron/hole pairs for a number of adjacent detector pixels, • A step of estimating the position of the centroid of the number of electron/hole pairs using the estimates of electron/hole pairs in adjacent detector pixels, • A step of estimating the impact position of the particle using said estimated position of the centroid, • A step of forming a pixelated image using the estimated position of a multitude of estimated impact positions, the pixelated image consisting of image pixels having an intensity, wherein, • When estimating the impact position said estimate has a position dependent bias depending on the position within the detector pixel, and • The contribution of each estimated impact position to corresponding image pixels is adjusted to counter the effect of said position dependent bias, characterized in that , the adjustment of the contribution of each estimated impact position to corresponding image pixels comprises directly adding intensity to several image pixels, thereby spreading out the contribution of each estimated impact position to said several image pixels. • A step of intercepting a particle of the particulate radiation, • A step of estimating the number of electron/hole pairs for a number of adjacent detector pixels, • A step of estimating the position of the centroid of the number of electron/hole pairs using the estimates of electron/hole pairs in adjacent detector pixels, • A step of estimating the impact position of the particle using said estimated position of the centroid, • A step of forming a pixelated image using the estimated position of a multitude of estimated impact positions, the pixelated image consisting of image pixels having an intensity, wherein, • When estimating the impact position said estimate has a position dependent bias depending on the position within the detector pixel, and • The contribution of each estimated impact position to corresponding image pixels is adjusted to counter the effect of said position dependent bias, characterized in that , the adjustment of the contribution of each estimated impact position to corresponding image pixels comprises directly adding intensity to several image pixels, thereby spreading out the contribution of each estimated impact position to said several image pixels.
A piercer plug, comprising: a plug body ; and a sprayed coating formed on a surface of the plug body , the sprayed coating containing an iron-based alloy and an oxide of the iron-based alloy, a chromium concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis being 3 to 20 mass %, wherein the chromium concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis is measured such that an X-ray is directed into the sprayed coating through its surface, the resulting X-ray fluorescence is detected with a Si drift detector, and the incident X-ray is generated by a 3 mm ø spot collimator with a target of Rh and an output of 40 kV × 100 μA, the chromium concentration being determined as a mass percentage, where the denominator is a total amount of all elements detected, and the numerator includes both a Cr amount in the iron-based alloy and a Cr amount in the oxides, wherein a proportion of oxides in the sprayed coating is 25 to 80 vol%, and wherein an iron concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis is 50 mass % or higher, and wherein the iron concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis is measured by the same measurement method as for the chromium concentration. a plug body ; and a sprayed coating formed on a surface of the plug body , the sprayed coating containing an iron-based alloy and an oxide of the iron-based alloy, a chromium concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis being 3 to 20 mass %, wherein the chromium concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis is measured such that an X-ray is directed into the sprayed coating through its surface, the resulting X-ray fluorescence is detected with a Si drift detector, and the incident X-ray is generated by a 3 mm ø spot collimator with a target of Rh and an output of 40 kV × 100 μA, the chromium concentration being determined as a mass percentage, where the denominator is a total amount of all elements detected, and the numerator includes both a Cr amount in the iron-based alloy and a Cr amount in the oxides, wherein a proportion of oxides in the sprayed coating is 25 to 80 vol%, and wherein an iron concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis is 50 mass % or higher, and wherein the iron concentration determined by analyzing the sprayed coating with X-ray fluorescence analysis is measured by the same measurement method as for the chromium concentration.
A multi-seat gate valve , which comprises: a body with a chamber and a fluid passage ; a gate positioned within the body , the gate including a pair of opposing non-parallel surfaces , a pair of opposing parallel surfaces (110a, 1 10b), and a bottom edge surface ; a pair of sealing members , wherein each sealing member is secured between the bottom edge surface on the gate and a pair of locking members until the gate valve is at a fully closed position; wherein each locking member is detachably coupled to i) the gate until the gate valve is at the fully closed position and ii) the body only when the gate valve is at the fully closed position and each sealing member is in position to seal the fluid passage , characterised in that each locking member is detachably coupled to a respective one of the pair of opposing parallel surfaces (110a, 11 0b) on the gate by a respective pin until the gate valve is at the fully closed position and each locking member is detachably coupled to a respective surface on the body by the respective pin when the gate valve is at the fully closed position. a body with a chamber and a fluid passage ; a gate positioned within the body , the gate including a pair of opposing non-parallel surfaces , a pair of opposing parallel surfaces (110a, 1 10b), and a bottom edge surface ; a pair of sealing members , wherein each sealing member is secured between the bottom edge surface on the gate and a pair of locking members until the gate valve is at a fully closed position; wherein each locking member is detachably coupled to i) the gate until the gate valve is at the fully closed position and ii) the body only when the gate valve is at the fully closed position and each sealing member is in position to seal the fluid passage , characterised in that each locking member is detachably coupled to a respective one of the pair of opposing parallel surfaces (110a, 11 0b) on the gate by a respective pin until the gate valve is at the fully closed position and each locking member is detachably coupled to a respective surface on the body by the respective pin when the gate valve is at the fully closed position.
An environmental control system comprising: a compression device including a compressor , a turbine , and an electric motor operably coupled by a shaft , characterised in that the electric motor and the turbine , are arranged in series relative to a flow of a first medium (A1); and the turbine , is arranged downstream from the electric motor relative to the flow of the first medium (A1). a compression device including a compressor , a turbine , and an electric motor operably coupled by a shaft , characterised in that the electric motor and the turbine , are arranged in series relative to a flow of a first medium (A1); and the turbine , is arranged downstream from the electric motor relative to the flow of the first medium (A1).
A closure cap for sealing an outlet end of a barrel of a medicament container , the outlet end having a radially widened rim and the outlet end being sealable by an elastomeric seal , wherein the elastomeric seal comprises a flange portion configured to abut in a longitudinal direction with the outlet end , the closure cap comprising: - a cap body comprising a retainer portion and a fastening portion , - wherein the retainer portion is configured to engage with the elastomeric seal , - wherein the fastening portion comprises a resiliently and radially deformable fastener comprising a snap feature configured to releasably engage with the radially widened rim of the outlet end , and - wherein a longitudinal distance (D) between the retainer portion and the snap feature is sized to receive the radially widened rim of the outlet end and the flange portion of the elastomeric seal between the retainer portion and the snap feature , characterized by - an outer flange portion protruding radially outwardly from at least one of the retainer portion and the fastening portion . - a cap body comprising a retainer portion and a fastening portion , - wherein the retainer portion is configured to engage with the elastomeric seal , - wherein the fastening portion comprises a resiliently and radially deformable fastener comprising a snap feature configured to releasably engage with the radially widened rim of the outlet end , and - wherein a longitudinal distance (D) between the retainer portion and the snap feature is sized to receive the radially widened rim of the outlet end and the flange portion of the elastomeric seal between the retainer portion and the snap feature , characterized by - an outer flange portion protruding radially outwardly from at least one of the retainer portion and the fastening portion .
A chemical method for the synthesis of phillyrin, characterized by comprising the following steps: 1) dissolving a glycosyl receptor phillygenin and a glycosyl donor in a first organic solvent for glycosylation in the presence of a catalyst and a molecular sieve under protection of an inert gas to obtain tetraacyl phillyrin, wherein the glycosyl donor is 2,3,4,6-tetra-O-acyl-D-glucopyranosyl trichloroacetimidate, the catalyst is a Lewis acid, the molecular sieve is an aluminosilicate molecular sieve or aluminosilicate powder, and the first organic solvent is dichloromethane, trichloromethane, 1,2-dichloroethane or toluene; 2) dissolving the tetraacyl phillyrin in a second organic solvent, adding sodium methoxide for deacylation, adding an acidic pH regulator to regulate pH value of the reaction mixture to neutral, and carrying out purification treatment to obtain phillyrin, wherein the second organic solvent is a mixed solution of dichloromethane and methanol. 1) dissolving a glycosyl receptor phillygenin and a glycosyl donor in a first organic solvent for glycosylation in the presence of a catalyst and a molecular sieve under protection of an inert gas to obtain tetraacyl phillyrin, wherein the glycosyl donor is 2,3,4,6-tetra-O-acyl-D-glucopyranosyl trichloroacetimidate, the catalyst is a Lewis acid, the molecular sieve is an aluminosilicate molecular sieve or aluminosilicate powder, and the first organic solvent is dichloromethane, trichloromethane, 1,2-dichloroethane or toluene; 2) dissolving the tetraacyl phillyrin in a second organic solvent, adding sodium methoxide for deacylation, adding an acidic pH regulator to regulate pH value of the reaction mixture to neutral, and carrying out purification treatment to obtain phillyrin, wherein the second organic solvent is a mixed solution of dichloromethane and methanol.