A multi-use ophthalmic product comprising a container with an integral bacterial protection system, a reservoir a dispensing tip, the container having an ophthalmic composition that is dispensed from the tip into the eye of a patient, an outer diameter which is the diameter of the tip of the nozzle at the point the drop exits the nozzle; an inner diameter which is the diameter of the nozzle at the point the drop exits the nozzle and to which internally the ophthalmic composition moves from the reservoir to the tip; wherein the ratio of the inner to the outer diameter of the dispensing tip is from 1:1 to 1:6 with the inner diameter of the dispensing tip is more than 0.3 mm and less than 2 mm and the outer diameter of the dispensing tip is more than 1mm and less than 4 mm, wherein the ophthalmic composition is a preservative-free aqueous solution of Chloramphenicol as the active pharmaceutical ingredient and contains pharmaceutically acceptable excipients selected so as to provide the following physical parameters to the solution: a) viscosity of less than 200 cPat 25 °C as measured by European pharmacopoeia requirements (Capillary viscometer method; 01/2005:20209) b) surface tension of less than 22 mN/m and more than 10 mN/m at 25 °C wherein the integral bacterial protection system uses a mechanical tip-seal technology to prevent bacterial contamination and the mechanical tip-seal technology comprises a spring loaded valve located directly below the dispensing tip orifice configured to immediately close the orifice with an outward movement when the pressure drops at the end of an actuation; and wherein the combination of the dispensing tip and the properties of the composition produce a dispensed drop volume of between 22 μl and 31 μl when the tip is at 45 ° and the variability between each drop dispensed is ± 7 μl. a container with an integral bacterial protection system, a reservoir a dispensing tip, the container having an ophthalmic composition that is dispensed from the tip into the eye of a patient, an outer diameter which is the diameter of the tip of the nozzle at the point the drop exits the nozzle; an inner diameter which is the diameter of the nozzle at the point the drop exits the nozzle and to which internally the ophthalmic composition moves from the reservoir to the tip; wherein the ratio of the inner to the outer diameter of the dispensing tip is from 1:1 to 1:6 with the inner diameter of the dispensing tip is more than 0.3 mm and less than 2 mm and the outer diameter of the dispensing tip is more than 1mm and less than 4 mm, wherein the ophthalmic composition is a preservative-free aqueous solution of Chloramphenicol as the active pharmaceutical ingredient and contains pharmaceutically acceptable excipients selected so as to provide the following physical parameters to the solution: a) viscosity of less than 200 cPat 25 °C as measured by European pharmacopoeia requirements (Capillary viscometer method; 01/2005:20209) b) surface tension of less than 22 mN/m and more than 10 mN/m at 25 °C a) viscosity of less than 200 cPat 25 °C as measured by European pharmacopoeia requirements (Capillary viscometer method; 01/2005:20209) b) surface tension of less than 22 mN/m and more than 10 mN/m at 25 °C wherein the integral bacterial protection system uses a mechanical tip-seal technology to prevent bacterial contamination and the mechanical tip-seal technology comprises a spring loaded valve located directly below the dispensing tip orifice configured to immediately close the orifice with an outward movement when the pressure drops at the end of an actuation; and wherein the combination of the dispensing tip and the properties of the composition produce a dispensed drop volume of between 22 μl and 31 μl when the tip is at 45 ° and the variability between each drop dispensed is ± 7 μl. <EOS>