mhurhangee/patent-ind-claim-en huggingface dataset:
A liquid formulation for use in a method of treating a pediatric cancer in a subject in need thereof, wherein the formulation comprises a therapeutically effective amount of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide having the formula (I) : a pharmaceutically acceptable salt thereof, or combinations thereof; a solubilizing agent comprising a β-cyclodextrin derivative; and a base; wherein: the formulation has a pH of about 2.5 to about 5.5; and the compound of formula (I), or a pharmaceutically acceptable salt thereof, or combinations thereof, has a concentration of about 15 mg/mL to about 35 mg/mL in the liquid formulation. a pharmaceutically acceptable salt thereof, or combinations thereof; a solubilizing agent comprising a β-cyclodextrin derivative; and a base; wherein: the formulation has a pH of about 2.5 to about 5.5; and a solubilizing agent comprising a β-cyclodextrin derivative; and a base; wherein: the formulation has a pH of about 2.5 to about 5.5; and the compound of formula (I), or a pharmaceutically acceptable salt thereof, or combinations thereof, has a concentration of about 15 mg/mL to about 35 mg/mL in the liquid formulation.
A carbon composite composition for manufacturing a resistance heating element , comprising: a binder; a lubricant; a specific resistance controlling agent; and a base material which comprises silicon carbide, wherein the base material determines a specific resistance of the resistance heating element at a high temperature; characterized in that the binder comprises a novolac resin, the specific resistance controlling agent comprises aluminum oxide and/or silicon oxide, and the lubricant comprises graphite. a binder; a lubricant; a specific resistance controlling agent; and a base material which comprises silicon carbide, wherein the base material determines a specific resistance of the resistance heating element at a high temperature; characterized in that the binder comprises a novolac resin, the specific resistance controlling agent comprises aluminum oxide and/or silicon oxide, and the lubricant comprises graphite.
A transmitter configured to transmit a first data sequence and a second data sequence by orthogonal frequency division multiplexing OFDM, the transmitter comprising: a mapper configured to obtain the first data sequence and the second data sequence, and combine and map the first data sequence and the second data sequence obtained onto a plurality of subcarriers which are OFDM subcarriers; and a framer configured to generate an OFDM signal from the plurality of subcarriers, wherein the mapper is configured to: map the first data sequence onto a plurality of first subcarriers out of the plurality of subcarriers, as a high power signal; and map the second data sequence onto the plurality of first subcarriers and a plurality of second subcarriers different from the plurality of first subcarriers, out of the plurality of subcarriers, as a low power signal, wherein power of the low power signal is lower than power of the high power signal, the first data sequence is not mapped onto the plurality of second subcarriers, and the plurality of first subcarriers consists of every n-th subcarrier of the plurality of subcarriers along the frequency axis, n being a predetermined integer larger than 1. a mapper configured to obtain the first data sequence and the second data sequence, and combine and map the first data sequence and the second data sequence obtained onto a plurality of subcarriers which are OFDM subcarriers; and a framer configured to generate an OFDM signal from the plurality of subcarriers, wherein the mapper is configured to: map the first data sequence onto a plurality of first subcarriers out of the plurality of subcarriers, as a high power signal; and map the second data sequence onto the plurality of first subcarriers and a plurality of second subcarriers different from the plurality of first subcarriers, out of the plurality of subcarriers, as a low power signal, wherein power of the low power signal is lower than power of the high power signal, the first data sequence is not mapped onto the plurality of second subcarriers, and the plurality of first subcarriers consists of every n-th subcarrier of the plurality of subcarriers along the frequency axis, n being a predetermined integer larger than 1. map the first data sequence onto a plurality of first subcarriers out of the plurality of subcarriers, as a high power signal; and map the second data sequence onto the plurality of first subcarriers and a plurality of second subcarriers different from the plurality of first subcarriers, out of the plurality of subcarriers, as a low power signal, wherein power of the low power signal is lower than power of the high power signal, the first data sequence is not mapped onto the plurality of second subcarriers, and the plurality of first subcarriers consists of every n-th subcarrier of the plurality of subcarriers along the frequency axis, n being a predetermined integer larger than 1.
A method of metal artefact reduction in x-ray dental volume tomography, the method comprising: a step (S1) of obtaining a sinogram of at least part (V) of a patient jaw , acquired through relatively rotating an x-ray source and a detector around the patient jaw ; the method being characterized by further comprising: a step (S2) of detecting metal objects in the sinogram by using at least a trained artificial intelligence algorithm to generate 3D masks which represent the metal objects in the sinogram ; and a step (S4;S5) of reconstructing a three dimensional tomographic image based on the sinogram and the 3D masks as generated. a step (S1) of obtaining a sinogram of at least part (V) of a patient jaw , acquired through relatively rotating an x-ray source and a detector around the patient jaw ; the method being characterized by further comprising: a step (S2) of detecting metal objects in the sinogram by using at least a trained artificial intelligence algorithm to generate 3D masks which represent the metal objects in the sinogram ; and a step (S4;S5) of reconstructing a three dimensional tomographic image based on the sinogram and the 3D masks as generated. a step (S2) of detecting metal objects in the sinogram by using at least a trained artificial intelligence algorithm to generate 3D masks which represent the metal objects in the sinogram ; and a step (S4;S5) of reconstructing a three dimensional tomographic image based on the sinogram and the 3D masks as generated.
Method for controlling a drive apparatus of a micro-oscillation mirror , wherein the drive apparatus has at least two comb drives which are arranged on different radial sides of a pivoting axis of the micro-oscillation mirror , wherein in the method: - at least two actuation signals (AS1, AS2) are generated, and the at least two comb drives are therefore actuated at least temporarily in such a way that they drive the micro-oscillation mirror in an oscillating fashion, - at least one elongation signal (P1, P2), which characterizes the elongation of the micro-oscillation mirror is generated using at least one comb drive , - at least one of the actuation signals (AS1, AS2) is adapted to the oscillation of the micro-oscillation mirror on the basis of at least one of the elongation signals (P1, P2), - during a transient recovery time of the micro-oscillation mirror at least one of the comb drives is connected, by means of at least one switching apparatus , alternately to an actuation apparatus for receiving at least one actuation signal (AS1, AS2) or to an elongation-detection apparatus for generating at least one elongation signal (P1, P2), characterized in that after a transient recovery time of the micro-oscillation mirror at least one of the comb drives is used exclusively to drive the micro-oscillation mirror , and at least one of the comb drives is used exclusively to detect the elongation of the micro-oscillation mirror . - at least two actuation signals (AS1, AS2) are generated, and the at least two comb drives are therefore actuated at least temporarily in such a way that they drive the micro-oscillation mirror in an oscillating fashion, - at least one elongation signal (P1, P2), which characterizes the elongation of the micro-oscillation mirror is generated using at least one comb drive , - at least one of the actuation signals (AS1, AS2) is adapted to the oscillation of the micro-oscillation mirror on the basis of at least one of the elongation signals (P1, P2), - during a transient recovery time of the micro-oscillation mirror at least one of the comb drives is connected, by means of at least one switching apparatus , alternately to an actuation apparatus for receiving at least one actuation signal (AS1, AS2) or to an elongation-detection apparatus for generating at least one elongation signal (P1, P2),
An ultrasound imaging apparatus for inspecting a volume of a subject , comprising: - an ultrasound probe including a plurality of ultrasound transducer elements for acquiring two-dimensional ultrasound image data in two intersecting image planes in the field of view, - an image processing unit coupled to the ultrasound probe for receiving the two-dimensional ultrasound image data in the two intersecting image planes and for determining an anatomical feature in the two intersecting image planes of the two-dimensional ultrasound image data, - an evaluation unit for evaluating the two-dimensional ultrasound image data and for determining a quality parameter based on a positional relation of the anatomical feature with respect to each of the image planes of the two-dimensional ultrasound image data in the field of view, wherein the positional relation is an outline of the anatomical feature with respect to the field of view in each of the image planes or a position of the anatomical feature with respect to an image depth of the two-dimensional ultrasound image data, and - an alignment unit for aligning or indicating an alignment of the image planes or the field of view based on the positional relation and the quality parameter, such that a position of the ultrasound probe can be aligned to the anatomical feature , wherein the ultrasound probe is further adapted to acquire three-dimensional ultrasound data in a field of view in the aligned position of the ultrasound probe . - an ultrasound probe including a plurality of ultrasound transducer elements for acquiring two-dimensional ultrasound image data in two intersecting image planes in the field of view, - an image processing unit coupled to the ultrasound probe for receiving the two-dimensional ultrasound image data in the two intersecting image planes and for determining an anatomical feature in the two intersecting image planes of the two-dimensional ultrasound image data, - an evaluation unit for evaluating the two-dimensional ultrasound image data and for determining a quality parameter based on a positional relation of the anatomical feature with respect to each of the image planes of the two-dimensional ultrasound image data in the field of view, wherein the positional relation is an outline of the anatomical feature with respect to the field of view in each of the image planes or a position of the anatomical feature with respect to an image depth of the two-dimensional ultrasound image data, and - an alignment unit for aligning or indicating an alignment of the image planes or the field of view based on the positional relation and the quality parameter, such that a position of the ultrasound probe can be aligned to the anatomical feature ,
A method of automatically controlling the mass flow rate of a gas through an orifice through which, in use, choked flow is arranged to occur, the method using a controller (350; 450) comprising an electronic valve located downstream of a gas source, a piezoelectric oscillator in contact with the gas upstream of the orifice and downstream of the electronic valve, a further piezoelectric oscillator in contact with the gas downstream of the orifice and a temperature sensor , wherein the piezoelectric oscillator has a resonant frequency which is proportional to the density of the gas upstream of the orifice, and wherein the density of gas upstream of the orifice is, under choked flow conditions, proportional to the mass flow rate through the orifice, the method comprising; a) driving the piezoelectric oscillator at a resonant frequency; b) driving the further piezoelectric oscillator at a resonant frequency; c) measuring the resonant frequency of the piezoelectric oscillator and the resonant frequency of the further piezoelectric oscillator; d) measuring, using the temperature sensor, the temperature of the gas; e) storing, in the controller, a pre-determined target value of a function derived from the resonant frequency of the piezoelectric oscillator, the resonant frequency of the further piezoelectric oscillator and the temperature and representative of a particular mass flow rate through the orifice; and f) controlling the electronic valve by means of an electronic feedback loop to minimise the difference between the target value and a function of the measured resonant frequency of the piezoelectric oscillator, the measured resonant frequency of the further piezoelectric oscillator and the measured temperature of the gas in order to maintain the particular mass flow rate of gas through said orifice. a) driving the piezoelectric oscillator at a resonant frequency; b) driving the further piezoelectric oscillator at a resonant frequency; c) measuring the resonant frequency of the piezoelectric oscillator and the resonant frequency of the further piezoelectric oscillator; d) measuring, using the temperature sensor, the temperature of the gas; e) storing, in the controller, a pre-determined target value of a function derived from the resonant frequency of the piezoelectric oscillator, the resonant frequency of the further piezoelectric oscillator and the temperature and representative of a particular mass flow rate through the orifice; and f) controlling the electronic valve by means of an electronic feedback loop to minimise the difference between the target value and a function of the measured resonant frequency of the piezoelectric oscillator, the measured resonant frequency of the further piezoelectric oscillator and the measured temperature of the gas in order to maintain the particular mass flow rate of gas through said orifice.
A self-recuperative burner comprising: a burner body having an exchanger ; said exchanger comprises a first duct for the combustion air and a second duct for the flue gases; it further comprises at least one first flue gas discharge pipe ; and an air inlet duct leading to a first annular chamber concentric to said at least one first flue gas discharge pipe ; characterized in that said first annular chamber being connected also to a Venturi tube positioned inside said at least one first flue gas discharge pipe .
Negotiation method for the delivery of a service to a terminal, comprising • sending (sp), from means for delivering the service to said terminal, a set of interaction propositions managed by the delivery means when said service is delivered, the set of propositions being configured so as to allow said terminal to indicate to said means for delivering said service that said terminal is able to accept at least one proposition from among the set of interaction propositions, each proposition of the set describing a list of at least two stimuli managed by the means for delivering the service to the terminal during the service session, the list of at least two stimuli for each proposition describing a list of interaction commands, one interaction command of which has to be transmitted by the terminal to the delivery means when the corresponding interaction is activated by the user by way of an interaction interface of the terminal, and each list of stimuli being different from the lists of stimuli of the other propositions and corresponding to a respective configuration of the interaction interface of the terminal. • sending (sp), from means for delivering the service to said terminal, a set of interaction propositions managed by the delivery means when said service is delivered, the set of propositions being configured so as to allow said terminal to indicate to said means for delivering said service that said terminal is able to accept at least one proposition from among the set of interaction propositions, each proposition of the set describing a list of at least two stimuli managed by the means for delivering the service to the terminal during the service session, the list of at least two stimuli for each proposition describing a list of interaction commands, one interaction command of which has to be transmitted by the terminal to the delivery means when the corresponding interaction is activated by the user by way of an interaction interface of the terminal, and each list of stimuli being different from the lists of stimuli of the other propositions and corresponding to a respective configuration of the interaction interface of the terminal.
Method for the manufacture of reduced graphene oxide from kish graphite comprising: A. The provision of kish graphite, B. A pre-treatment step of said kish graphite comprising the following successive sub-steps: i. A sieving step wherein the kish graphite is classified by size as follows: a) Kish graphite having a size below 50μm, b) Kish graphite having a size above or equal to 50μm, the fraction a) of kish graphite having a size below 50 μm being removed, ii. A flotation step with the fraction b) of kish graphite having a size above or equal to 50μm, iii. An acid leaching step wherein an acid is added so that the ratio in weight (acid amount)/(kish graphite amount) is between 0.25 and 1.0, iv. Optionally, the kish graphite is washed and dried, C. An oxidation step of the pre-treated kish-graphite obtained after step B) in order to obtain graphene oxide and D. A reduction of graphene oxide into reduced graphene oxide. A. The provision of kish graphite, B. A pre-treatment step of said kish graphite comprising the following successive sub-steps: i. A sieving step wherein the kish graphite is classified by size as follows: a) Kish graphite having a size below 50μm, b) Kish graphite having a size above or equal to 50μm, the fraction a) of kish graphite having a size below 50 μm being removed, ii. A flotation step with the fraction b) of kish graphite having a size above or equal to 50μm, iii. An acid leaching step wherein an acid is added so that the ratio in weight (acid amount)/(kish graphite amount) is between 0.25 and 1.0, iv. Optionally, the kish graphite is washed and dried, i. A sieving step wherein the kish graphite is classified by size as follows: a) Kish graphite having a size below 50μm, b) Kish graphite having a size above or equal to 50μm, the fraction a) of kish graphite having a size below 50 μm being removed, a) Kish graphite having a size below 50μm, b) Kish graphite having a size above or equal to 50μm, the fraction a) of kish graphite having a size below 50 μm being removed, ii. A flotation step with the fraction b) of kish graphite having a size above or equal to 50μm, iii. An acid leaching step wherein an acid is added so that the ratio in weight (acid amount)/(kish graphite amount) is between 0.25 and 1.0, iv. Optionally, the kish graphite is washed and dried, C. An oxidation step of the pre-treated kish-graphite obtained after step B) in order to obtain graphene oxide and D. A reduction of graphene oxide into reduced graphene oxide.
A weighing device comprising: a conveyance unit configured to convey an article; a hopper configured to receive the article conveyed by the conveyance unit, temporarily hold the received article, and then discharge the article downstream; a detection unit configured to detect the article between a conveyance end of the conveyance unit and the hopper; and a control unit configured to control driving of the conveyance unit; characterized in that the control unit is configured to drive the conveyance unit for a first period when the detection unit does not detect the article at a start of driving of the conveyance unit, and the control unit is configured to drive the conveyance unit for a second period longer than the first period when the detection unit detects the article at a start of driving of the conveyance unit. a conveyance unit configured to convey an article; a hopper configured to receive the article conveyed by the conveyance unit, temporarily hold the received article, and then discharge the article downstream; a detection unit configured to detect the article between a conveyance end of the conveyance unit and the hopper; and a control unit configured to control driving of the conveyance unit; characterized in that the control unit is configured to drive the conveyance unit for a first period when the detection unit does not detect the article at a start of driving of the conveyance unit, and the control unit is configured to drive the conveyance unit for a second period longer than the first period when the detection unit detects the article at a start of driving of the conveyance unit.
A multilayer barrier film, comprising: a smooth layer having a major surface; and a barrier layer directly disposed on the major surface of the smooth layer, wherein the smooth layer comprises a thiol-ene material as a polymeric matrix material, wherein the smooth layer further comprises particles having an average dimension in the range from 2 nm to 2 micron hosted by the polymeric matrix material, and wherein the thiol-ene material is formed by curing one or more polythiol monomers with one or more polyene monomers. a smooth layer having a major surface; and a barrier layer directly disposed on the major surface of the smooth layer, wherein the smooth layer comprises a thiol-ene material as a polymeric matrix material, wherein the smooth layer further comprises particles having an average dimension in the range from 2 nm to 2 micron hosted by the polymeric matrix material, and wherein the thiol-ene material is formed by curing one or more polythiol monomers with one or more polyene monomers.
A medical-device system , comprising: a stimulation control circuit configured to provide cardiac stimulation signals for delivery to a patient according to a set of stimulation parameters: determine a parameter update schedule indicating a timing at which to update at least a portion of the set of stimulation parameters using an atrioventricular conduction characteristic of the patient; and dynamically update at least the portion of the set of stimulation parameters according to the determined timing; wherein the stimulation control circuit is configured to determine the parameter update schedule using a variability metric of the atrioventricular conduction characteristic, and wherein the stimulation control circuit is configured to reduce a parameter update rate corresponding to a heart rate or heart rate range if the variability metric of the atrioventricular conduction characteristic values is below a variability threshold, and to increase the parameter update rate if the variability metric of the atrioventricular conduction characteristic is above the variability threshold. determine a parameter update schedule indicating a timing at which to update at least a portion of the set of stimulation parameters using an atrioventricular conduction characteristic of the patient; and dynamically update at least the portion of the set of stimulation parameters according to the determined timing; wherein the stimulation control circuit is configured to determine the parameter update schedule using a variability metric of the atrioventricular conduction characteristic, and wherein the stimulation control circuit is configured to reduce a parameter update rate corresponding to a heart rate or heart rate range if the variability metric of the atrioventricular conduction characteristic values is below a variability threshold, and to increase the parameter update rate if the variability metric of the atrioventricular conduction characteristic is above the variability threshold.