A system for simulating bilateral injection of contrast agent into a patient, the system comprising: an x-ray imaging device; and a controller operative to: acquire a first image set of a first blood vessel having contrast agent therein via the x-ray imaging device; acquire a second image set of a second blood vessel having contrast agent therein via the x-ray imaging device; and generate a third image set based at least in part on the first image set and the second image set, wherein the third image set includes at least one composite image that depicts both the first blood vessel and the second blood vessel; wherein the controller is further operative to generate the at least one composite image by: identifying an image pair that includes a first image from the first image set and a second image from the second image set; splitting the first image and the second image into high-frequency components and low-frequency components; and combining the first image and the second image based at least in part on the high-frequency components and the low-frequency components. an x-ray imaging device; and a controller operative to: acquire a first image set of a first blood vessel having contrast agent therein via the x-ray imaging device; acquire a second image set of a second blood vessel having contrast agent therein via the x-ray imaging device; and generate a third image set based at least in part on the first image set and the second image set, wherein the third image set includes at least one composite image that depicts both the first blood vessel and the second blood vessel; wherein the controller is further operative to generate the at least one composite image by: identifying an image pair that includes a first image from the first image set and a second image from the second image set; splitting the first image and the second image into high-frequency components and low-frequency components; and combining the first image and the second image based at least in part on the high-frequency components and the low-frequency components. acquire a first image set of a first blood vessel having contrast agent therein via the x-ray imaging device; acquire a second image set of a second blood vessel having contrast agent therein via the x-ray imaging device; and generate a third image set based at least in part on the first image set and the second image set, wherein the third image set includes at least one composite image that depicts both the first blood vessel and the second blood vessel; wherein the controller is further operative to generate the at least one composite image by: identifying an image pair that includes a first image from the first image set and a second image from the second image set; splitting the first image and the second image into high-frequency components and low-frequency components; and combining the first image and the second image based at least in part on the high-frequency components and the low-frequency components. identifying an image pair that includes a first image from the first image set and a second image from the second image set; splitting the first image and the second image into high-frequency components and low-frequency components; and combining the first image and the second image based at least in part on the high-frequency components and the low-frequency components. <EOS>