mhurhangee/patent-ind-claim-en huggingface dataset:
A method for reprogramming a fibroblast or skin cell into a pluripotent stem cell, comprising: (a) culturing the fibroblast or skin cell; (b) transfecting the cell with one or more synthetic RNA molecules, wherein the one or more synthetic RNA molecules include at least one RNA molecule encoding one or more reprogramming factors and wherein the transfecting results in the fibroblast or skin cell expressing the one or more reprogramming factors; and (c) repeating step (b) between one and nine times, wherein the amount of one or more synthetic RNA molecules transfected in one or more later transfections is greater than the amount transfected in one or more earlier transfections, thereby resulting in the fibroblast or skin cell being reprogrammed into a pluripotent stem cell, wherein steps (a)-(c) are performed without using feeder cells; preferably, the fibroblast or skin cell is derived from a biopsy; optionally, the biopsy is a full-thickness dermal punch biopsy. (a) culturing the fibroblast or skin cell; (b) transfecting the cell with one or more synthetic RNA molecules, wherein the one or more synthetic RNA molecules include at least one RNA molecule encoding one or more reprogramming factors and wherein the transfecting results in the fibroblast or skin cell expressing the one or more reprogramming factors; and (c) repeating step (b) between one and nine times, wherein the amount of one or more synthetic RNA molecules transfected in one or more later transfections is greater than the amount transfected in one or more earlier transfections, thereby resulting in the fibroblast or skin cell being reprogrammed into a pluripotent stem cell,
An accessory for an inhaler , the inhaler having an air inlet for the entry of air into the inhaler and an air outlet for communication with the mouth of a patient, such that inhalation by a patient through the air outlet causes an inhalation air flow (F1) through the inhaler from the air inlet to the air outlet, the inhaler further defining a mixing zone between the air inlet and the air outlet for mixing the inhalation air flow (F1) with a drug, the accessory comprising an accessory housing ; a pressure port ; an electronic sensor for determining a flow rate of the inhalation air flow (F1), the electronic sensor being received in the accessory housing , the electronic sensor being in communication with the pressure port , the electronic sensor being sensitive to a pressure change at the pressure port caused by the inhalation air flow (F1); and a fastening structure for fastening the accessory to the inhaler , the fastening structure being configured to fasten the accessory to an exterior of the inhaler in such a manner that the pressure port is arranged upstream from the air inlet of the inhaler and the mixing zone with respect to the inhalation air flow (F1), characterized in that the pressure port is formed by a plurality of openings in the accessory housing , the openings being distributed circumferentially along a circumference of the air inlet of the inhaler when the accessory is fastened to the inhaler . an accessory housing ; a pressure port ; an electronic sensor for determining a flow rate of the inhalation air flow (F1), the electronic sensor being received in the accessory housing , the electronic sensor being in communication with the pressure port , the electronic sensor being sensitive to a pressure change at the pressure port caused by the inhalation air flow (F1); and a fastening structure for fastening the accessory to the inhaler , the fastening structure being configured to fasten the accessory to an exterior of the inhaler in such a manner that the pressure port is arranged upstream from the air inlet of the inhaler and the mixing zone with respect to the inhalation air flow (F1), characterized in that the pressure port is formed by a plurality of openings in the accessory housing , the openings being distributed circumferentially along a circumference of the air inlet of the inhaler when the accessory is fastened to the inhaler .
A long steel pipe for reel-lay installation comprising a plurality of electric resistance welded steel pipes joined in a pipe longitudinal direction with a girth weld provided therebetween, wherein the plurality of electric resistance welded steel pipes include adjacent electric resistance welded steel pipes that are adjacent to other, characterized in that a seam position of one of the adjacent electric resistance welded steel pipes being defined as a 0 o'clock cross-sectional position and positions that evenly divide a pipe cross section of other of the adjacent electric resistance welded steel pipes into 12 sections around a pipe axis being defined as the 0 o'clock cross-sectional position to an 11 o'clock cross-sectional position in a clockwise order, and in that the plurality of electric resistance welded steel pipes are joined such that the 0 o'clock cross-sectional position of the one of the adjacent electric resistance welded steel pipes faces an area from the 2 o'clock cross-sectional position to the 4 o'clock cross-sectional position or an area from the 8 o'clock cross-sectional position to the 10 o'clock cross-sectional position of the other of the adjacent electric resistance welded steel pipes.
A flow meter , comprising: a flow conduit ; a driver configured to vibrate the conduit ; a first pick-off including a first pick-off component and a second pick-off component ; a reference member disposed proximate the flow conduit , wherein the first pick-off component is coupled to the reference member and the second pick-off component is coupled to the conduit proximate the first pick-off component ; and characterized by : an active portion of the reference member adapted to vibrate about a bending axis (W-W); and a balancing element coupled to the reference member sized and located such that a momentum of the balancing element is substantially opposite and equal to or greater than a momentum of the active portion of the reference member . about the bending axis (W-W) a flow conduit ; a driver configured to vibrate the conduit ; a first pick-off including a first pick-off component and a second pick-off component ; a reference member disposed proximate the flow conduit , wherein the first pick-off component is coupled to the reference member and the second pick-off component is coupled to the conduit proximate the first pick-off component ; and characterized by : an active portion of the reference member adapted to vibrate about a bending axis (W-W); and a balancing element coupled to the reference member sized and located such that a momentum of the balancing element is substantially opposite and equal to or greater than a momentum of the active portion of the reference member . about the bending axis (W-W)
Device for cutting food, comprising a cutting unit having a rotatable carrier , a slicing knife associated with the carrier for slicing the food, , wherein the cutting unit furthermore comprises at least one dicing knife for dicing the food, and a protection element which is designed to be arranged vis-à-vis a side of the carrier where the dicing knife is present, for delimiting a dicing space for the dicing knife to move through during operation, and wherein the protection element is equipped with at least one annular groove at a side for facing the carrier , characterized in that the at least one dicing knife is associated with the carrier and in that the at least one annular groove is for receiving a free end of the dicing knife associated with the carrier .
Support bracket for supporting a slat of a garden wire panel of the type constructed from a wire mesh with vertical wires between which the slats are arranged and from horizontal transverse wires , the support bracket being carried out as a profile with a hook-shaped portion with which the support bracket can be hooked over a transverse wire and a support portion for supporting a slat , wherein the support portion substantially consists of a beamlike element, characterized in that the beamlike element comprises at least four sides with at least four ribs in between, the support portion being connected to the hook-shaped portion in a first rib.
A sonotrode for friction welding of at least two joining parts consisting at least partly of weldable plastic, comprising: a) a longitudinal axis, along which the sonotrode is deflectable during operation, b) a working surface, which is arranged laterally to the sonotrode with respect to the longitudinal axis, so that the working surface is arranged at an outer side surface of the sonotrode and that joining energy may be laterally introduced into a joining zone between a first and a second joining part and which can abut the first joining part during operation, wherein c) the working surface has a first structure, the shape of which is adaptable to a form of at least the second joining part . a) a longitudinal axis, along which the sonotrode is deflectable during operation, b) a working surface, which is arranged laterally to the sonotrode with respect to the longitudinal axis, so that the working surface is arranged at an outer side surface of the sonotrode and that joining energy may be laterally introduced into a joining zone between a first and a second joining part and which can abut the first joining part during operation, wherein c) the working surface has a first structure, the shape of which is adaptable to a form of at least the second joining part .
A buoyant element, comprising a rigid elongate buoyancy tube defining a floodable envelope that holds a mass of buoyant macrospheres within, the buoyancy tube having a void that extends between and around the mass of macrospheres inside the buoyancy tube and having multiple openings that are in fluid communication with the void, wherein each opening has a diameter that is smaller than the diameter of the macrospheres so as to retain the macrospheres in the buoyancy tube , and wherein the void is flooded with water , the buoyant element being characterised in that the openings penetrate a tubular wall of the buoyancy tube and are distributed longitudinally along the length of the buoyancy tube .
A pump to motor connection system for an implantable blood pump , comprising: a pump housing including an impeller disposed therein; a motor housing including a motor disposed therein, the motor housing being spaced a distance from the pump housing ; a flexible outer sheath coupling the pump housing to the motor housing , the outer sheath defining a maximum total length between 7 and 10 centimeters; and an inner shaft coaxial with the outer sheath , the inner shaft coupling the motor to the impeller ; wherein the pump housing is sized to be received and configured to be implanted within the left ventricle and the motor housing is sized to be received and configured to be implanted within the ascending aorta; or wherein the pump housing is sized to be received and configured to be implanted within the right ventricle and the motor housing is sized to be received and configured to be implanted downstream of a pulmonary valve. a pump housing including an impeller disposed therein; a motor housing including a motor disposed therein, the motor housing being spaced a distance from the pump housing ; a flexible outer sheath coupling the pump housing to the motor housing , the outer sheath defining a maximum total length between 7 and 10 centimeters; and a motor housing including a motor disposed therein, the motor housing being spaced a distance from the pump housing ; a flexible outer sheath coupling the pump housing to the motor housing , the outer sheath defining a maximum total length between 7 and 10 centimeters; and an inner shaft coaxial with the outer sheath , the inner shaft coupling the motor to the impeller ; wherein the pump housing is sized to be received and configured to be implanted within the left ventricle and the motor housing is sized to be received and configured to be implanted within the ascending aorta; or wherein the pump housing is sized to be received and configured to be implanted within the right ventricle and the motor housing is sized to be received and configured to be implanted downstream of a pulmonary valve.
A lifting system for a mobility device comprising: A bracket configured to be fixed to the mobility device, a hoist connector configured to removably connect to the bracket to provide lifting of the mobility device in use; where one of the bracket and the hoist connector comprises a pin and the other of the bracket and the hoist connector comprises a clip , the pin comprising a head formation and a neck formation, wherein the clip comprises an aperture configured to pass over the head formation in use when the aperture and head formation are aligned and to pass into engagement with the neck formation such that the clip is loosely held on the pin , where the aperture has a close fit with the head formation to prevent unintentional disengagement from the pin in use, wherein a biasing member is arranged to bias the clip away from a condition in which the aperture is aligned with the head formation when in engagement with the pin , characterised in that the biasing member comprises a magnet provided on the pin or clip , and where the other of the pin or clip comprises a magnet or magnetic material such that pin and clip are attracted together such as to retain the clip on the pin . A bracket configured to be fixed to the mobility device, a hoist connector configured to removably connect to the bracket to provide lifting of the mobility device in use; where one of the bracket and the hoist connector comprises a pin and the other of the bracket and the hoist connector comprises a clip , the pin comprising a head formation and a neck formation, wherein the clip comprises an aperture configured to pass over the head formation in use when the aperture and head formation are aligned and to pass into engagement with the neck formation such that the clip is loosely held on the pin , where the aperture has a close fit with the head formation to prevent unintentional disengagement from the pin in use, wherein a biasing member is arranged to bias the clip away from a condition in which the aperture is aligned with the head formation when in engagement with the pin , characterised in that the biasing member comprises a magnet provided on the pin or clip , and where the other of the pin or clip comprises a magnet or magnetic material such that pin and clip are attracted together such as to retain the clip on the pin .
A display assembly for attachment with a vulcanized rubber article comprising one or more display layers , an intermediate layer , and an adhesive layer : wherein the one or more display layers are of elastomeric material configured to provide a display indicia; wherein the intermediate layer is formed from an elastomeric material that is different from that of the one or more display layers, wherein the material is capable of acting as a barrier to minimize or prevent the migration of any constituents of the adhesive layer and/or the vulcanized rubber article to the one or more display layers, wherein the intermediate layer is interposed between the adhesive layer and the one or more display layers, wherein the intermediate layer is in direct contact with one of the one or more display layers and with the adhesive layer, and wherein the one or more display layers and the intermediate layer are joined together by vulcanizing; wherein the adhesive layer is formed from a material capable of forming a chemical bond or being vulcanized with a surface of the vulcanized rubber article; wherein the display assembly further comprises a cavity disposed therein; and wherein the intermediate layer is formed from an elastomeric material, and the elastomeric material includes gum rubber, vulcanized natural rubber, SBR, nitrile rubber, polyurethane, or combinations thereof. wherein the one or more display layers are of elastomeric material configured to provide a display indicia; wherein the intermediate layer is formed from an elastomeric material that is different from that of the one or more display layers, wherein the material is capable of acting as a barrier to minimize or prevent the migration of any constituents of the adhesive layer and/or the vulcanized rubber article to the one or more display layers, wherein the intermediate layer is interposed between the adhesive layer and the one or more display layers, wherein the intermediate layer is in direct contact with one of the one or more display layers and with the adhesive layer, and wherein the one or more display layers and the intermediate layer are joined together by vulcanizing; wherein the adhesive layer is formed from a material capable of forming a chemical bond or being vulcanized with a surface of the vulcanized rubber article; wherein the display assembly further comprises a cavity disposed therein; and wherein the intermediate layer is formed from an elastomeric material, and the elastomeric material includes gum rubber, vulcanized natural rubber, SBR, nitrile rubber, polyurethane, or combinations thereof.
System for monitoring the filling of a set of waste containers which are distributed over a site with a high density of passers-by, the monitoring system comprising: - an autonomous monitoring box which is provided on each waste container , each autonomous monitoring box including a power source which supplies power to at least one fill sensor of the waste container and to a transmitter suitable for transmitting data to a remote processing terminal ; - a relay unit which is positioned within a transmission radius of the transmitter of asub-set of waste containers , the relay unit being suitable for relaying, to the remote processing terminal , the data transmitted by the transmitter of each monitoring box ; characterized in that the monitoring system comprises: - at least one mobile terminal suitable for receiving, in real time, the fill rate of each waste container provided with an autonomous monitoring box , allowing at least one operator patrolling a site and provided with a mobile terminal to receive, in real time, information regarding the fill rate of the waste containers on the site, and - a monitoring interface which allows the progress of filling and emptying of each waste container to be monitored, the processing terminal being configured to transmit an alert to the mobile terminal when the fill level of a waste container reaches a threshold predefined by the monitoring interface . - an autonomous monitoring box which is provided on each waste container , each autonomous monitoring box including a power source which supplies power to at least one fill sensor of the waste container and to a transmitter suitable for transmitting data to a remote processing terminal ; - a relay unit which is positioned within a transmission radius of the transmitter of asub-set of waste containers , the relay unit being suitable for relaying, to the remote processing terminal , the data transmitted by the transmitter of each monitoring box ; - at least one mobile terminal suitable for receiving, in real time, the fill rate of each waste container provided with an autonomous monitoring box , allowing at least one operator patrolling a site and provided with a mobile terminal to receive, in real time, information regarding the fill rate of the waste containers on the site, and - a monitoring interface which allows the progress of filling and emptying of each waste container to be monitored, the processing terminal being configured to transmit an alert to the mobile terminal when the fill level of a waste container reaches a threshold predefined by the monitoring interface .
A gNodeB centralized unit comprising: means for receiving, from a gNodeB distributed unit, information indicating the gNodeB distributed unit's capability for generating other-system information, wherein the other-system information comprises system information other than master information block and system information block 1 information; means for transmitting, to the gNodeB distributed unit, a request for the other-system information, wherein the other-system information comprises time reference information generated by the gNodeB distributed unit; means for receiving a delivery of the other-system information from the gNodeB distributed unit; and means for generating system information broadcast information to be sent via dedicated signaling to at least one user equipment based at least in part on the other-system information. means for receiving, from a gNodeB distributed unit, information indicating the gNodeB distributed unit's capability for generating other-system information, wherein the other-system information comprises system information other than master information block and system information block 1 information; means for transmitting, to the gNodeB distributed unit, a request for the other-system information, wherein the other-system information comprises time reference information generated by the gNodeB distributed unit; means for receiving a delivery of the other-system information from the gNodeB distributed unit; and means for generating system information broadcast information to be sent via dedicated signaling to at least one user equipment based at least in part on the other-system information.
A cable routing system comprising: a duct comprising a continuous flange structure , a continuous rear surface , and two sequentially arranged duct segments each including opposing walls configured to provide some flexibility and defining a main fiber channel therebetween, the main fiber channel being configured to receive a drop fiber so that the drop fiber snugly fits within the main fiber channel ; wherein the main fiber channel comprises a longitudinal opening extending parallel to the longitudinal axis of the drop fiber and wherein the main fiber channel has a width that corresponds to a width slightly less than the diameter of the drop fiber; wherein the continuous flange structure is configured to provide support for the cable routing system as the cable routing system is installed on or fastened to a wall or other generally flat surface; wherein the continuous rear surface comprises a generally flat surface shaped to receive an adhesive backing having a removable liner ; and wherein the duct is formed of a polymeric material. a duct comprising a continuous flange structure , a continuous rear surface , and two sequentially arranged duct segments each including opposing walls configured to provide some flexibility and defining a main fiber channel therebetween, the main fiber channel being configured to receive a drop fiber so that the drop fiber snugly fits within the main fiber channel ; wherein the main fiber channel comprises a longitudinal opening extending parallel to the longitudinal axis of the drop fiber and wherein the main fiber channel has a width that corresponds to a width slightly less than the diameter of the drop fiber; wherein the continuous flange structure is configured to provide support for the cable routing system as the cable routing system is installed on or fastened to a wall or other generally flat surface; wherein the continuous rear surface comprises a generally flat surface shaped to receive an adhesive backing having a removable liner ; and wherein the duct is formed of a polymeric material.