A device for thermoacoustic sensing, in particular thermoacoustic imaging, the device comprising a) an irradiation unit configured to - generate electromagnetic or particle radiation, - modulate an intensity and/or frequency of the electromagnetic or particle radiation, respectively, with a first modulation, the first modulation comprising at least two modulation components at distinct frequencies, and - continuously emit the modulated electromagnetic or particle radiation, respectively, towards a target , whereby acoustic waves are continuously generated in the target , the acoustic waves exhibiting a second modulation, the second modulation comprising acoustic wave components at the distinct frequencies of the at least two modulation components and/or at harmonic frequencies of the distinct frequencies of the at least two modulation components, b) a detection unit configured to simultaneously detect the acoustic waves exhibiting the second modulation while the modulated electromagnetic or particle radiation, respectively, is being continuously emitted towards the target , whereby the acoustic wave components at the distinct frequencies and/or at the harmonic frequencies are detected, and c) a processing unit configured to determine thermoacoustic values of an amplitude and/or a phase of each of the acoustic wave components at the distinct frequencies of the at least two modulation components and/or the harmonic frequencies of the distinct frequencies of the at least two modulation components. a) an irradiation unit configured to - generate electromagnetic or particle radiation, - modulate an intensity and/or frequency of the electromagnetic or particle radiation, respectively, with a first modulation, the first modulation comprising at least two modulation components at distinct frequencies, and - continuously emit the modulated electromagnetic or particle radiation, respectively, towards a target , whereby acoustic waves are continuously generated in the target , the acoustic waves exhibiting a second modulation, the second modulation comprising acoustic wave components at the distinct frequencies of the at least two modulation components and/or at harmonic frequencies of the distinct frequencies of the at least two modulation components, - generate electromagnetic or particle radiation, - modulate an intensity and/or frequency of the electromagnetic or particle radiation, respectively, with a first modulation, the first modulation comprising at least two modulation components at distinct frequencies, and - continuously emit the modulated electromagnetic or particle radiation, respectively, towards a target , whereby acoustic waves are continuously generated in the target , the acoustic waves exhibiting a second modulation, the second modulation comprising acoustic wave components at the distinct frequencies of the at least two modulation components and/or at harmonic frequencies of the distinct frequencies of the at least two modulation components, b) a detection unit configured to simultaneously detect the acoustic waves exhibiting the second modulation while the modulated electromagnetic or particle radiation, respectively, is being continuously emitted towards the target , whereby the acoustic wave components at the distinct frequencies and/or at the harmonic frequencies are detected, and c) a processing unit configured to determine thermoacoustic values of an amplitude and/or a phase of each of the acoustic wave components at the distinct frequencies of the at least two modulation components and/or the harmonic frequencies of the distinct frequencies of the at least two modulation components. <EOS>