mhurhangee/patent-ind-claim-en huggingface dataset:
A method for monitoring post-translational modifications of protein, the method comprising: providing a first microbead by binding a protein antibody to a surface of a base bead; providing a second microbead by binding a target protein having a first post-translational modification or a second post-translational modification, which are inversely proportional to each other, to the protein antibody of the first microbead, wherein the first post-translational modification is phosphorylated tau protein, and the second post-translational modification is O-glycosylated tau protein; providing a third microbead by binding the second microbead to a first post-translational modification antibody that selectively binds to the first post-translational modification of the target protein; providing a fourth microbead by binding the second microbead to a second post-translational modification antibody that selectively binds to the second post-translational modification of the target protein; and measuring impedances of the third microbead and the fourth microbead, respectively; obtaining a ratio of a first difference to a second difference, wherein the first difference is a difference between the impedances of the third microbead and a reference impedance, and the second difference is a difference between the impedances of the fourth microbead and the reference impedance; determining whether the first post-translational modification or the second post-translational modification is increased or decreased based on the ratio of the first difference to the second difference. providing a first microbead by binding a protein antibody to a surface of a base bead; providing a second microbead by binding a target protein having a first post-translational modification or a second post-translational modification, which are inversely proportional to each other, to the protein antibody of the first microbead, wherein the first post-translational modification is phosphorylated tau protein, and the second post-translational modification is O-glycosylated tau protein; providing a third microbead by binding the second microbead to a first post-translational modification antibody that selectively binds to the first post-translational modification of the target protein; providing a fourth microbead by binding the second microbead to a second post-translational modification antibody that selectively binds to the second post-translational modification of the target protein; and measuring impedances of the third microbead and the fourth microbead, respectively; obtaining a ratio of a first difference to a second difference, wherein the first difference is a difference between the impedances of the third microbead and a reference impedance, and the second difference is a difference between the impedances of the fourth microbead and the reference impedance; determining whether the first post-translational modification or the second post-translational modification is increased or decreased based on the ratio of the first difference to the second difference.
Torque transmission device for a drive train of a vehicle having - a flywheel or another rotational part which has at least one flywheel mass , and - a centrifugal force pendulum module which has a plurality of pendulum masses and a carrier device which supports the pendulum masses , which centrifugal force pendulum module is connected to the rotational part , characterized by a disc-shaped plate element which is connected to the carrier device and/or the rotational part and in which at least one balance recess for balancing or for setting of a predefined unbalance is configured. - a flywheel or another rotational part which has at least one flywheel mass , and - a centrifugal force pendulum module which has a plurality of pendulum masses and a carrier device which supports the pendulum masses , which centrifugal force pendulum module is connected to the rotational part ,
Laboratory balance comprising a base body , a weighing chamber with a weighing chamber floor and a weighing chamber rear wall , and further comprising a draft shield (5,5',5") with a top wall , a first side wall , a second side wall arranged parallel to the first side wall , and a front wall , wherein the weighing chamber floor , the draft shield (5,5',5") and the weighing chamber rear wall together enclose the weighing chamber , characterized in that the weighing chamber rear wall comprises a base module and a top module (16,16',16"), and further that the base module is connected to the base body , and that the top module (16,16',16") is connected to the top wall of the draft shield (5,5',5").
A gynecological brachytherapy applicator comprising an elongate cylindrical body having a proximal end and a distal end, the elongate body comprising a modular support matrix having a plurality of source lumens extending at least partially therethrough and defining an arrangement of the source lumens within the elongate body, wherein the modular support matrix comprises a plurality of segments , each segment including a matrix comprising an array of channels , whereby the collective alignment of the channels forms a pathway for the insertion of source lumens therethrough, characterized in that : each segment is radially compressible, providing the elongate body an uncompressed configuration and a radially compressed configuration when subject to a compressive force.
A peptide which consists of i) LGTFLK (SEQ ID NO:19) or LGTFLKA (SEQ ID NO: 21) ii) or a sequence according to SEQ ID NO: 19 or 21 wherein the N-terminus is in the form of an acetyl group, and/or the C-terminus is in the form of an amide group; and wherein all the amino acids are in D configuration. i) LGTFLK (SEQ ID NO:19) or LGTFLKA (SEQ ID NO: 21) ii) or a sequence according to SEQ ID NO: 19 or 21 wherein the N-terminus is in the form of an acetyl group, and/or the C-terminus is in the form of an amide group;
An electrolytic capacitor comprising: a cathode comprising a conductive substrate and a conductive polymer layer placed on a surface of the conductive substrate; an anode comprising a substrate composed of a valve metal and a dielectric layer composed of an oxide of the valve metal that is placed on a surface of the substrate and is so placed that the dielectric layer and the conductive polymer layer of the cathode face each other through a space; and an ion conductive electrolyte having no electron conductivity which is filled in the space, characterized in that the conductive substrate comprises: an aluminum foil with an aluminum oxide film; and an inorganic conductive layer comprising an inorganic conductive material that is placed on a surface of the aluminum oxide film, the inorganic conductive layer and the aluminum foil are electrically connected to each other, and the inorganic conductive material is at least one material selected from a group consisting of carbon, titanium, titanium nitride, titanium carbide, and nickel, the conductive polymer layer is placed on a surface of the inorganic conductive layer , a contact resistance between the conductive substrate and the conductive polymer layer in the cathode is 1 Ωcm 2 or less, and the conductive polymer layer of the cathode that is in contact with the ion conductive electrolyte expresses a redox capacity when a voltage is applied between the anode and the cathode. a cathode comprising a conductive substrate and a conductive polymer layer placed on a surface of the conductive substrate; an anode comprising a substrate composed of a valve metal and a dielectric layer composed of an oxide of the valve metal that is placed on a surface of the substrate and is so placed that the dielectric layer and the conductive polymer layer of the cathode face each other through a space; and an ion conductive electrolyte having no electron conductivity which is filled in the space, characterized in that the conductive substrate comprises: an aluminum foil with an aluminum oxide film; and an inorganic conductive layer comprising an inorganic conductive material that is placed on a surface of the aluminum oxide film, the inorganic conductive layer and the aluminum foil are electrically connected to each other, and the inorganic conductive material is at least one material selected from a group consisting of carbon, titanium, titanium nitride, titanium carbide, and nickel, the conductive polymer layer is placed on a surface of the inorganic conductive layer , a contact resistance between the conductive substrate and the conductive polymer layer in the cathode is 1 Ωcm 2 or less, and the conductive polymer layer of the cathode that is in contact with the ion conductive electrolyte expresses a redox capacity when a voltage is applied between the anode and the cathode.
A chorionic gonadotropin carboxy terminal peptide (CTP)-modified polypeptide comprising a growth hormone for use in a method of treating a growth hormone deficiency in a human child subject as measured by maintaining insulin like growth factor (IGF-1) levels within a normal therapeutic range, wherein the CTP-modified polypeptide comprises one chorionic gonadotropin carboxy terminal peptide (CTP) attached to the amino terminus of the growth hormone, and two chorionic gonadotropin CTPs attached in tandem to the carboxy terminus of the growth hormone, wherein the method comprises administering to the human child subject a therapeutically effective amount of the CTP-modified polypeptide once per week at a dose of 1 to 60 milligrams per week (mg/week).
A polyolefin composition comprising: (A) a polyolefin homo- or copolymer, (B) a metal hydroxide in an amount of 30 to 60 wt% based on the weight of the polyolefin composition, (C) a borate in an amount of 5 to 25 wt% based on the weight of the polyolefin composition, wherein the borate comprises calcium borate; and (D) a silicone fluid or gum in an amount of 0.1 to 20 wt% based on the weight of the polyolefin composition. (A) a polyolefin homo- or copolymer, (B) a metal hydroxide in an amount of 30 to 60 wt% based on the weight of the polyolefin composition, (C) a borate in an amount of 5 to 25 wt% based on the weight of the polyolefin composition, wherein the borate comprises calcium borate; and (D) a silicone fluid or gum in an amount of 0.1 to 20 wt% based on the weight of the polyolefin composition.
A waste collection unit for collecting waste material through a plurality of suction lines during a medical procedure, said unit comprising: a portable cart ; a first waste container supported by said portable cart and adapted for connection to one of the suction lines to collect the waste material during the medical procedure; a second waste container supported by said portable cart and adapted for connection to another of the suction lines to collect the waste material during the medical procedure; a vacuum source in selective communication with both of said first and second waste containers for providing a vacuum in both of said first and second waste containers simultaneously to draw the waste materials into said waste containers through the suction lines; a first vacuum regulator in fluid communication with said vacuum source for regulating a vacuum level in said first waste container; and a second vacuum regulator in fluid communication with said vacuum source for regulating a vacuum level in said second waste container; wherein a control system is in communication with said first and second vacuum regulators and adapted for simultaneously controlling said first and second vacuum regulators to control the vacuum levels in said first and second waste containers such that different vacuum levels can be established in said first and second waste containers. a portable cart ; a first waste container supported by said portable cart and adapted for connection to one of the suction lines to collect the waste material during the medical procedure; a second waste container supported by said portable cart and adapted for connection to another of the suction lines to collect the waste material during the medical procedure; a vacuum source in selective communication with both of said first and second waste containers for providing a vacuum in both of said first and second waste containers simultaneously to draw the waste materials into said waste containers through the suction lines; a first vacuum regulator in fluid communication with said vacuum source for regulating a vacuum level in said first waste container; and a second vacuum regulator in fluid communication with said vacuum source for regulating a vacuum level in said second waste container; wherein a control system is in communication with said first and second vacuum regulators and adapted for simultaneously controlling said first and second vacuum regulators to control the vacuum levels in said first and second waste containers such that different vacuum levels can be established in said first and second waste containers.
A healthcare bed which comprises: - a frame surmounted by a lying surface which is articulated into multiple sections , corresponding to the regions of the back, buttocks, thighs and legs of the patient, and comprising a fixed part , substantially on the horizontal plane, and a moveable part which supports a first section , corresponding to the back region, which can be at least inclined with respect to said fixed part , - means for tilting said first section , said bed being characterized in that a second section , corresponding to the buttocks region, is pivoted at the side thereof that is adjacent to a third section , corresponding to the thigh region, and is free at the opposite side, there being means for supporting and moving said second section from a configuration that is coplanar with respect to said lying surface to a configuration that is inclined and with the free side lowered, and vice versa. - a frame surmounted by a lying surface which is articulated into multiple sections , corresponding to the regions of the back, buttocks, thighs and legs of the patient, and comprising a fixed part , substantially on the horizontal plane, and a moveable part which supports a first section , corresponding to the back region, which can be at least inclined with respect to said fixed part , - means for tilting said first section ,
A punch pin having a working end surface , wherein the working end surface comprises a plurality of lobes and a plurality of flutes , said working end surface having a major diameter extending between opposing lobes , and a minimum diameter extending between opposing flutes ; wherein: the major diameter is at least 46-49% larger than the minimum diameter; and each of the lobes and flutes generally elliptically curved.
A micro-electromechanical system, MEMS, microphone comprising: a membrane having a predetermined stiffness and a central region ; at least one spring , the at least one spring having a first end and a second end , wherein the first end of the at least one spring is connected to the membrane ; a backplate , wherein the second end of the at least one spring is connected to the backplate ; a support connected to the central region of the membrane and connected to the backplate , wherein the support is positioned between the central region of the membrane and the backplate , wherein the MEMS microphone comprises only a single spring as the at least one spring , wherein the membrane is circular and is configured to flex around the support when the membrane receives incident acoustic pressure, wherein the MEMS microphone is characterised in that the single spring is formed from a slice of the membrane along a portion of a perimeter of the membrane and is configured to provide an electrical connection point to the membrane . a membrane having a predetermined stiffness and a central region ; at least one spring , the at least one spring having a first end and a second end , wherein the first end of the at least one spring is connected to the membrane ; a backplate , wherein the second end of the at least one spring is connected to the backplate ; a support connected to the central region of the membrane and connected to the backplate , wherein the support is positioned between the central region of the membrane and the backplate , the MEMS microphone comprises only a single spring as the at least one spring , wherein the membrane is circular and is configured to flex around the support when the membrane receives incident acoustic pressure,
A composition for use in preventing, improving or treating a bone loss-related disease, comprising cyclo(his-pro) (CHP) or a pharmaceutically acceptable salt thereof; and parathyroid hormone (PTH).
A pulse wave detector comprising: a body portion including a pulse wave detection sensor which detects a pulse wave from an artery in a wrist of a user; and a strip-shaped band member for securing the body portion to the wrist, wherein in a secured state where the body portion is secured to the wrist with the band member , the body portion is placed in a position where a process of an ulna in the wrist or a process of a radius in the wrist is exposed, wherein the band member includes a first region , and a second region which is higher in stretchability than the first region , wherein in the secured state, the second region is at least in contact with the process of the ulna in the wrist or the process of the radius in the wrist, characterized in that a stretchability of the second region in a longitudinal direction of the band member is lower than a stretchability of the second region in a direction perpendicular to the longitudinal direction. a body portion including a pulse wave detection sensor which detects a pulse wave from an artery in a wrist of a user; and a strip-shaped band member for securing the body portion to the wrist, wherein in a secured state where the body portion is secured to the wrist with the band member , the body portion is placed in a position where a process of an ulna in the wrist or a process of a radius in the wrist is exposed, wherein the band member includes a first region , and a second region which is higher in stretchability than the first region , wherein in the secured state, the second region is at least in contact with the process of the ulna in the wrist or the process of the radius in the wrist, characterized in that a stretchability of the second region in a longitudinal direction of the band member is lower than a stretchability of the second region in a direction perpendicular to the longitudinal direction.
A method for integrating tags with items , comprising: - turning a reel by an amount that allows a portion of an elongate narrow substrate that includes a first tag of a plurality of tags to be paid out, the elongate narrow substrate having a width of between 0.0254 mm (0.001 inches) and 0.0508 mm (0.002 inches) and a thickness of between 0.00254 mm (0.0001 inches) and 0.0635 mm (0.0025 inches), wherein each of the plurality of tags comprises at least one antenna formed of a trace or wire disposed on the elongate narrow substrate and a communication enabled device coupled to the elongate narrow substrate so as to have an electrical coupling or connection with the at least one antenna ; - dynamically tuning , by decreasing a thickness of the trace disposed on the elongate narrow substrate , the first tag to optimize tag performance in view of dielectric and tuning properties of a first item being fabricated; - cutting the elongate narrow substrate so as to cause the first tag to be placed on the first item being fabricated; and - coupling the first tag to the first item being fabricated, wherein a total tag thickness is 0.127 mm (0.005 inches) to 0.356 mm (0.014 inches). - turning a reel by an amount that allows a portion of an elongate narrow substrate that includes a first tag of a plurality of tags to be paid out, the elongate narrow substrate having a width of between 0.0254 mm (0.001 inches) and 0.0508 mm (0.002 inches) and a thickness of between 0.00254 mm (0.0001 inches) and 0.0635 mm (0.0025 inches), wherein each of the plurality of tags comprises at least one antenna formed of a trace or wire disposed on the elongate narrow substrate and a communication enabled device coupled to the elongate narrow substrate so as to have an electrical coupling or connection with the at least one antenna ; - dynamically tuning , by decreasing a thickness of the trace disposed on the elongate narrow substrate , the first tag to optimize tag performance in view of dielectric and tuning properties of a first item being fabricated; - cutting the elongate narrow substrate so as to cause the first tag to be placed on the first item being fabricated; and - coupling the first tag to the first item being fabricated,
A system for processing packets between a router and a transmission control protocol/Internet protocol (TCP/IP) network, comprising: a plurality of large scale network address translation (LSN) appliances (20a-20d); wherein a first LSN appliance arbitrarily selected from the plurality of LSN appliances is configured to: receive a request from the router , wherein the request includes a private IP address; apply a hash function to the private IP address to determine an owner appliance from the plurality of LSN appliances (20a-20d), and route the request to the owner appliance; wherein the owner appliance is configured to forward the request to the TCP/IP network using a public IP address associated with the owner appliance, wherein the owner appliance creates a session that translates between the public IP address and the private IP address; wherein a second LSN appliance arbitrarily selected from the plurality of LSN appliances (20a-20d) is configured to: receive a response from the TCP/IP network, wherein the response includes the public IP address; examine a look-up table to determine the owner appliance based on the public IP address; route the response to the owner appliance; wherein the owner appliance is configured to forward the response along with the private IP address to the router . a plurality of large scale network address translation (LSN) appliances (20a-20d); wherein a first LSN appliance arbitrarily selected from the plurality of LSN appliances is configured to: receive a request from the router , wherein the request includes a private IP address; apply a hash function to the private IP address to determine an owner appliance from the plurality of LSN appliances (20a-20d), and route the request to the owner appliance; receive a request from the router , wherein the request includes a private IP address; apply a hash function to the private IP address to determine an owner appliance from the plurality of LSN appliances (20a-20d), and route the request to the owner appliance; wherein the owner appliance is configured to forward the request to the TCP/IP network using a public IP address associated with the owner appliance, wherein the owner appliance creates a session that translates between the public IP address and the private IP address; wherein a second LSN appliance arbitrarily selected from the plurality of LSN appliances (20a-20d) is configured to: receive a response from the TCP/IP network, wherein the response includes the public IP address; examine a look-up table to determine the owner appliance based on the public IP address; route the response to the owner appliance; receive a response from the TCP/IP network, wherein the response includes the public IP address; examine a look-up table to determine the owner appliance based on the public IP address; route the response to the owner appliance; wherein the owner appliance is configured to forward the response along with the private IP address to the router .