mhurhangee/patent-ind-claim-en huggingface dataset:
A tubing retention device usable with a peristaltic pump , the tubing retention device comprising: a movable tubing retainer having a tubing engaging portion capable of engaging with a first surface of a tube and a track receiving portion ; a second tubing engaging portion capable of engaging with a second surface of the tube ; a track portion for movably supporting the tubing retainer , wherein the track portion is located within a cavity , the track portion comprising a pair of opposing tracks configured to slidably engage opposite sides of the track receiving portion of the movable tubing retainer , and a cover plate configured to cover the movable tubing retainer and the track portion , wherein at least a portion of the cover plate facing the tubing retainer has a surface with a reduced friction coefficient; and a biasing member biasing the movable tubing retainer towards the second tubing engagement portion , wherein engagement of the tubing retainer and the second tubing engaging portion is capable of reducing longitudinal movement of the tube , and wherein at least one of the track receiving portion of the movable tubing retainer or the track portion have a surface with a friction reducing coating. a movable tubing retainer having a tubing engaging portion capable of engaging with a first surface of a tube and a track receiving portion ; a second tubing engaging portion capable of engaging with a second surface of the tube ; a track portion for movably supporting the tubing retainer , wherein the track portion is located within a cavity , the track portion comprising a pair of opposing tracks configured to slidably engage opposite sides of the track receiving portion of the movable tubing retainer , and a cover plate configured to cover the movable tubing retainer and the track portion , wherein at least a portion of the cover plate facing the tubing retainer has a surface with a reduced friction coefficient; and a biasing member biasing the movable tubing retainer towards the second tubing engagement portion ,
A composition for use in the treatment of an ear disorder comprising (+)-azasetron, of Formula ( R )-I: or a pharmaceutically acceptable salt and/or solvate thereof, and at least one pharmaceutically acceptable excipient, wherein the composition comprises at least a 90: 10 w/w mixture of (+)-azasetron of Formula ( R )-I:(-)-azasetron, or pharmaceutically acceptable salts and/or solvates thereof. and at least one pharmaceutically acceptable excipient, wherein the composition comprises at least a 90: 10 w/w mixture of (+)-azasetron of Formula ( R )-I:(-)-azasetron, or pharmaceutically acceptable salts and/or solvates thereof.
Calibrated rotary pressing device for ground coffee powder, of the type called lever dynamometric tamper and intended to exert compression and rotation on the dose of coffee (202 - 203) that is ground and dispensed inside the filter of a filter-holding bowl , which comprises a load-bearing structure with a lever that vertically translates a cylindrical rotary pressing unit that integrates telescopic means, which are connected at the lower end to a circular disc and which are intended to compact in a controlled way the coffee in said filter and comprise a pushing spring that, by activating said lever , transfers onto said telescopic means and thus onto said disc a calibrated, that is to say dynamometric, pressure; said rotary pressing unit also integrating means for rotation simultaneous to the activation of said lever and to said calibrated pressure; said rotary pressing device being characterised in that said rotary pressing unit transfers said rotation to the disc only in the phase of return of the activation lever , that is to say, lifting it, by means of internal movement means (101 - 110) vertically integrated along a longitudinal barycentric axis ; said rotary pressing unit (100 - 110), of the compact type and consisting of an internally hollow cylindrical body , being closed on the top and open on the bottom for housing a pushing spring of the gas piston type arranged in abutment on the top so that the rod protrudes downwards and pushes, along said axis , a shaft constrained to it in such a way as to slide on the same axis transferring to said disc (110, 202 - 203) a calibrated and regular compression during its stroke , and wherein said shaft is also provided with a helical passing-through slot , which is crossed by a transverse pin that is integral with the cylindrical body being horizontally fixed on two holes obtained in it, said slot causing said shaft to rotate on itself simultaneously to said vertical sliding , like one single integrated track; and wherein between said shaft and said disc a bearing is interposed, which is of the one-way type, that is to say, freewheeling in one direction of rotation, and which is housed in a bushing connected to the disc , in such a way as to transfer to it the rotary motion of said shaft (104 - 105) only in the phase of return of said lever and not in the operation movement, thus freewheeling during the lowering of the lever only with compression on said powder .
A functionalized optical element comprising: an optical base element; and a functionalized layered structure incorporating at least one functional layer which is glued directly to the optical base element to form a functionalized optical element, characterized in that the optical element further includes a bi-layer adhesive structure which comprises a layer of gamma-aminopropyltriethoxysilane adhesive disposed on a surface of said functionalized layered structure and a layer of hot melt adhesive (HMA) disposed between the gamma-aminopropyltriethoxysilane layer and the optical base element to form a bi-layer adhesive that permanently retains the functionalized layered structure on the optical base element while maintaining optical quality. an optical base element; and a functionalized layered structure incorporating at least one functional layer which is glued directly to the optical base element to form a functionalized optical element, characterized in that the optical element further includes a bi-layer adhesive structure which comprises a layer of gamma-aminopropyltriethoxysilane adhesive disposed on a surface of said functionalized layered structure and a layer of hot melt adhesive (HMA) disposed between the gamma-aminopropyltriethoxysilane layer and the optical base element to form a bi-layer adhesive that permanently retains the functionalized layered structure on the optical base element while maintaining optical quality.
Nimotuzumab for use in a method of treating pancreatic ductal adenocarcinoma (PDAC) in a patient having PDAC, wherein the PDAC expresses KRAS wild-type.
A glass-ceramic container , comprising: a body formed of a glass-ceramic material and comprising a hollow interior defined by a circumferential sidewall formed symmetrically around a central vertical axis , an open top end , and a bottom end , wherein the circumferential sidewall comprises: a peripheral region defined by a volume of the circumferential sidewall , the peripheral region comprising secondary crystal phases of the glass-ceramic material and a fracture toughness of Y MPa ∗ m^1/2, wherein the secondary crystal phases of the glass-ceramic material are not optically transparent, and a contracted region defined by a volume of the circumferential sidewall disposed closer to the central axis than the peripheral region and comprising primary crystal phases of the glass-ceramic material and a fracture toughness of X MPa ∗ m^1/2, wherein the primary crystal phases of glass-ceramic material are optically transparent, and wherein Y is greater than X. a body formed of a glass-ceramic material and comprising a hollow interior defined by a circumferential sidewall formed symmetrically around a central vertical axis , an open top end , and a bottom end , wherein the circumferential sidewall comprises: a peripheral region defined by a volume of the circumferential sidewall , the peripheral region comprising secondary crystal phases of the glass-ceramic material and a fracture toughness of Y MPa ∗ m^1/2, wherein the secondary crystal phases of the glass-ceramic material are not optically transparent, and a contracted region defined by a volume of the circumferential sidewall disposed closer to the central axis than the peripheral region and comprising primary crystal phases of the glass-ceramic material and a fracture toughness of X MPa ∗ m^1/2, wherein the primary crystal phases of glass-ceramic material are optically transparent, and wherein Y is greater than X. a peripheral region defined by a volume of the circumferential sidewall , the peripheral region comprising secondary crystal phases of the glass-ceramic material and a fracture toughness of Y MPa ∗ m^1/2, wherein the secondary crystal phases of the glass-ceramic material are not optically transparent, and a contracted region defined by a volume of the circumferential sidewall disposed closer to the central axis than the peripheral region and comprising primary crystal phases of the glass-ceramic material and a fracture toughness of X MPa ∗ m^1/2, wherein the primary crystal phases of glass-ceramic material are optically transparent, and wherein Y is greater than X.
Use of a free radical initiator composition in melt processing of polyethylene materials comprising at least one ethylene copolymer with a density ≥ 850 kg/m 3 and < 905 kg/m 3 for the reduction of gels in polyethylene materials characterized in that the free radical initiator composition is added in quantities ≥ 0.001 wt% and ≤ 0.029 wt% compared to the total weight of the polyethylene material, wherein further the melt processing is performed in a melt processing unit, wherein the free radical initiator composition is dosed to the melt processing unit in a stage where the polyethylene material is in a molten condition and melt processing is conducted at a temperature of ≥ 160 °C and ≤ 240 °C, the density being determined according to ISO 1183-1 , method A.
A pressure relief system including a pressure relief assembly and a duct, the duct having an interior volume defined by a sidewall and a relief aperture defined through the sidewall of the duct, the pressure relief system comprising: a cover configured to seal the relief aperture when positioned in a closed configuration and to expose the relief aperture to an external environment when positioned in an open configuration; a first chamber at least partially defined by the sidewall and having a first volume fluidly coupled to the interior volume of the duct through a first orifice ; a second chamber at least partially defined by the sidewall and having a second volume fluidly coupled to the interior volume of the duct through a second orifice , the second orifice having a larger area than an area of the first orifice; and a piston coupled to the cover, positioned between the first chamber and the second chamber and defining a wall of the first chamber and the second chamber, and configured to change the first volume and the second volume in response to a change in pressure in at least the first chamber or the second chamber, the piston also configured to move the cover between the open and the closed configuration. a cover configured to seal the relief aperture when positioned in a closed configuration and to expose the relief aperture to an external environment when positioned in an open configuration; a first chamber at least partially defined by the sidewall and having a first volume fluidly coupled to the interior volume of the duct through a first orifice ; a second chamber at least partially defined by the sidewall and having a second volume fluidly coupled to the interior volume of the duct through a second orifice , the second orifice having a larger area than an area of the first orifice; and a piston coupled to the cover, positioned between the first chamber and the second chamber and defining a wall of the first chamber and the second chamber, and configured to change the first volume and the second volume in response to a change in pressure in at least the first chamber or the second chamber, the piston also configured to move the cover between the open and the closed configuration.
A timer management method, applied to a terminal device, the method comprising: obtaining, by the terminal device, a first physical downlink control channel, PDCCH; and determining, by the terminal device, whether to stop or start or restart a timer, when the first PDCCH is scrambled by using a cell radio network temporary identifier, C-RNTI, wherein the timer is a semi-persistent scheduling, SPS, timer; wherein the determining whether to stop or start or restart the timer comprises: determining, by the terminal device, when meeting a second condition, to start or restart the timer, the second condition being a criterion for the terminal device to determine whether to start the timer; wherein the determining, by the terminal device, when meeting a second condition, to start or restart the timer comprises: starting or restarting the timer, by the terminal device, when determining that the terminal device is configured with SPS resources, wherein the configured SPS resources are not used to perform any transmission when the SPS timer is running. obtaining, by the terminal device, a first physical downlink control channel, PDCCH; and determining, by the terminal device, whether to stop or start or restart a timer, when the first PDCCH is scrambled by using a cell radio network temporary identifier, C-RNTI, wherein the timer is a semi-persistent scheduling, SPS, timer; wherein the determining whether to stop or start or restart the timer comprises: determining, by the terminal device, when meeting a second condition, to start or restart the timer, the second condition being a criterion for the terminal device to determine whether to start the timer; wherein the determining, by the terminal device, when meeting a second condition, to start or restart the timer comprises: starting or restarting the timer, by the terminal device, when determining that the terminal device is configured with SPS resources, wherein the configured SPS resources are not used to perform any transmission when the SPS timer is running. determining, by the terminal device, when meeting a second condition, to start or restart the timer, the second condition being a criterion for the terminal device to determine whether to start the timer; wherein the determining, by the terminal device, when meeting a second condition, to start or restart the timer comprises: starting or restarting the timer, by the terminal device, when determining that the terminal device is configured with SPS resources, wherein the configured SPS resources are not used to perform any transmission when the SPS timer is running.
An acellular tissue matrix comprising an extracellular matrix of a decellularized tissue for use in a method to prevent the formation of a seroma or hematoma by approximating separated tissue by implanting the acellular tissue matrix into a space between two or more separated tissue planes. wherein the implanted acellular tissue matrix comprises a foam capable of supporting migration and proliferation of cells from surrounding tissue following implantation.
A tracheostoma heat and moisture exchanging device, comprising: a housing having a first opening that is adapted to open to a tracheostoma and a second opening that opens to ambient; a foam filter disposed in the housing ; a closure member mounted to the housing and adapted to close a passage extending through the housing ; a locking mechanism engageable to prevent movement of the closure member to close the passage and disengageable to allow movement of the closure member to close the passage; characterized by the closure member including a body portion and a plurality of legs each engaged with a corresponding channel in an inner surface of the housing , the body portion being movable from an open position spaced from the housing to a closed position engaging the housing and the locking mechanism including at least one ledge disposed in the inner surface of the housing that in a first position is engageable with at least one of the legs of the closure member to prevent movement of the closure member to close the passage and wherein the closure member is rotatable relative to the housing to a second position wherein the at least one leg is out of alignment with the at least one ledge to allow movement of the closure member to the closed position. a housing having a first opening that is adapted to open to a tracheostoma and a second opening that opens to ambient; a foam filter disposed in the housing ; a closure member mounted to the housing and adapted to close a passage extending through the housing ; a locking mechanism engageable to prevent movement of the closure member to close the passage and disengageable to allow movement of the closure member to close the passage; characterized by the closure member including a body portion and a plurality of legs each engaged with a corresponding channel in an inner surface of the housing , the body portion being movable from an open position spaced from the housing to a closed position engaging the housing and the locking mechanism including at least one ledge disposed in the inner surface of the housing that in a first position is engageable with at least one of the legs of the closure member to prevent movement of the closure member to close the passage and wherein the closure member is rotatable relative to the housing to a second position wherein the at least one leg is out of alignment with the at least one ledge to allow movement of the closure member to the closed position.
A material testing machine, which performs a three-point bending test on a testing piece , comprising: a support mechanism having a pair of support points for supporting the testing piece , an indenter that is connected to an ultrasonic oscillator and gives ultrasonic vibration to the testing piece by abutting against the testing piece , and a load mechanism that presses the indenter to the testing piece supported by the support mechanism ; characterized in that the support mechanism comprises: a spherical seat that has a lower member equipped with a spherical-surface-shaped concave portion or convex portion, and an upper member equipped with a spherical-surface-shaped concave portion or convex portion having a shape corresponding to the concave portion or convex portion in the lower member ; a holding portion that supports the testing piece on the upper member ; and a first movable member that causes the upper member to slide along the spherical surface with respect to the lower member . a support mechanism having a pair of support points for supporting the testing piece , an indenter that is connected to an ultrasonic oscillator and gives ultrasonic vibration to the testing piece by abutting against the testing piece , and a load mechanism that presses the indenter to the testing piece supported by the support mechanism ; characterized in that the support mechanism comprises: a spherical seat that has a lower member equipped with a spherical-surface-shaped concave portion or convex portion, and an upper member equipped with a spherical-surface-shaped concave portion or convex portion having a shape corresponding to the concave portion or convex portion in the lower member ; a holding portion that supports the testing piece on the upper member ; and a first movable member that causes the upper member to slide along the spherical surface with respect to the lower member . a spherical seat that has a lower member equipped with a spherical-surface-shaped concave portion or convex portion, and an upper member equipped with a spherical-surface-shaped concave portion or convex portion having a shape corresponding to the concave portion or convex portion in the lower member ; a holding portion that supports the testing piece on the upper member ; and a first movable member that causes the upper member to slide along the spherical surface with respect to the lower member .
A hydrocyclone (5a; 5c; 5d; 5d'; 5e) configured for separation of cells in a suspension, comprising: - a cell culture inlet ; - a hydrocyclone separation part into which a cell culture can be introduced from the cell culture inlet ; - a top outlet through which a part of the cell culture with decreased cell concentration can be transferred after separation in the hydrocyclone separation part ; - a bottom outlet through which a part of the cell culture with increased cell concentration can be transferred after separation in the hydrocyclone separation part ; and - a connection device which is provided to surround the bottom outlet of the hydrocyclone (5a; 5c; 5d; 5d'; 5e) leaving a free space around it such that the cell culture transferred out from the bottom outlet is allowed to freely discharge around the bottom outlet , wherein said connection device comprises an aseptic connector and wherein said connection device is a tubular part connected to the hydrocyclone (5a; 5c; 5d; 5d'; 5e) symmetrically around the bottom outlet , further characterised in that said hydrocyclone (5a; 5b; 5c; 5d, 5d'; 5e) is produced from plastic and is a pre-sterilized single-use component. - a cell culture inlet ; - a hydrocyclone separation part into which a cell culture can be introduced from the cell culture inlet ; - a top outlet through which a part of the cell culture with decreased cell concentration can be transferred after separation in the hydrocyclone separation part ; - a bottom outlet through which a part of the cell culture with increased cell concentration can be transferred after separation in the hydrocyclone separation part ; and - a connection device which is provided to surround the bottom outlet of the hydrocyclone (5a; 5c; 5d; 5d'; 5e) leaving a free space around it such that the cell culture transferred out from the bottom outlet is allowed to freely discharge around the bottom outlet , wherein said connection device comprises an aseptic connector and wherein said connection device is a tubular part connected to the hydrocyclone (5a; 5c; 5d; 5d'; 5e) symmetrically around the bottom outlet , further characterised in that said hydrocyclone (5a; 5b; 5c; 5d, 5d'; 5e) is produced from plastic and is a pre-sterilized single-use component.
A structural duct bearing system comprising stays or beams forming a plurality of bearing structures, at least one roller supporting structure , a plurality of motor driven rollers , at least one arresting type support , a plurality of metallic supports or inserts, wherein the stays or beams are accommodating in the bearing structure thereof the at least one roller supporting structure for bearing the motor driven rollers screwed to the stays or beams, the said at least one roller supporting structure further accommodating the arresting type support welded thereto for connecting the roller supporting structure to the stays or beams , the stays or beams having a substantially circular shape, made up of distinct or modular sections, following the geometrical contour of a tunnel having walls and a floor , wherein the same are placed, the stays or beams being installed in the tunnel by being directly fastened to the walls thereof, and wherein the structural duct bearing system further comprises fastening elements and screws , wherein the fastening to walls comprises the prior installation of the plurality of metallic supports using said fastening elements and screws for subsequently screwing the stays or beams to the walls of the tunnel.