mhurhangee/patent-ind-claim-en huggingface dataset:
A method of forming an organic transistor comprising the steps of: providing a substrate; forming a gate electrode on the substrate; forming a gate insulating film on the gate electrode; forming source and drain electrodes on the gate insulating film and forming an organic semiconductor layer on the source and drain electrodes and on the gate insulating film, wherein the drain electrode includes a first part disposed in a first region which is directly above the gate electrode, and a second part disposed in a second region which is not above the gate electrode, the drain electrode further comprising a connecting part connecting said first and second parts, said connecting part having a width smaller than both the width of the first part and the width of the second part, the method being characterised in that the organic semiconductor layer is formed by an inkjet printing process of an organic semiconductor material dissolved in an organic solvent, wherein the surface area of the gate insulating film on which the source-drain electrodes are not disposed has a surface energy of 40 mN/m or less. providing a substrate; forming a gate electrode on the substrate; forming a gate insulating film on the gate electrode; forming source and drain electrodes on the gate insulating film and forming an organic semiconductor layer on the source and drain electrodes and on the gate insulating film, wherein the drain electrode includes a first part disposed in a first region which is directly above the gate electrode, and a second part disposed in a second region which is not above the gate electrode, the drain electrode further comprising a connecting part connecting said first and second parts, said connecting part having a width smaller than both the width of the first part and the width of the second part, the method being characterised in that the organic semiconductor layer is formed by an inkjet printing process of an organic semiconductor material dissolved in an organic solvent, wherein the surface area of the gate insulating film on which the source-drain electrodes are not disposed has a surface energy of 40 mN/m or less.
A method of removing an undesired sequence from a double stranded nucleic acid library comprising: (a) providing said double stranded nucleic acid library, comprising a plurality of double stranded nucleic acid molecules, wherein each double stranded nucleic acid molecule comprises a first adapter region, a target sequence region, and a second adapter region, and wherein at least one of said double stranded nucleic acid molecules comprises said undesired sequence; (b) contacting said double stranded nucleic acid library with a nucleic acid modifying moiety that specifically binds to said undesired sequence; wherein said nucleic acid modifying moiety comprises a guide RNA molecule-directed endonuclease; (c) cleaving said undesired sequence such that said first adapter region and said second adapter region are not physically joined through said target sequence region; and (d) sequencing said double stranded nucleic acid library using a sequencing approach that requires said first adapter region and said second adapter region spanning said target sequence region. (a) providing said double stranded nucleic acid library, comprising a plurality of double stranded nucleic acid molecules, wherein each double stranded nucleic acid molecule comprises a first adapter region, a target sequence region, and a second adapter region, and wherein at least one of said double stranded nucleic acid molecules comprises said undesired sequence; (b) contacting said double stranded nucleic acid library with a nucleic acid modifying moiety that specifically binds to said undesired sequence; wherein said nucleic acid modifying moiety comprises a guide RNA molecule-directed endonuclease; (c) cleaving said undesired sequence such that said first adapter region and said second adapter region are not physically joined through said target sequence region; and (d) sequencing said double stranded nucleic acid library using a sequencing approach that requires said first adapter region and said second adapter region spanning said target sequence region.
A portable fluid spraying system comprising: a handheld fluid sprayer comprising: a fluid reservoir configured to store a fluid; a pump configured to pump the fluid from the fluid reservoir to an outlet of the handheld fluid sprayer ; a handle ; and a first trigger proximate the handle , configured to control fluid flow to the outlet ; a fluid hose having a coupling mechanism configured to removably couple to the handheld fluid sprayer proximate the outlet ; and a fluid spray gun comprising: a gun inlet configured to couple to the fluid hose and receive the fluid from the handheld fluid sprayer ; a gun outlet configured to expel the fluid in a spray pattern; and a second trigger configured to control fluid flow to the gun outlet , wherein the first trigger actuates a valve of the handheld fluid sprayer that controls the fluid flow; characterised in that the coupling mechanism comprises a pin configured to mechanically actuate the valve of the handheld fluid sprayer when the fluid hose is coupled to the handheld fluid sprayer. a fluid reservoir configured to store a fluid; a pump configured to pump the fluid from the fluid reservoir to an outlet of the handheld fluid sprayer ; a handle ; and a first trigger proximate the handle , configured to control fluid flow to the outlet ; a fluid hose having a coupling mechanism configured to removably couple to the handheld fluid sprayer proximate the outlet ; and a fluid spray gun comprising: a gun inlet configured to couple to the fluid hose and receive the fluid from the handheld fluid sprayer ; a gun outlet configured to expel the fluid in a spray pattern; and a second trigger configured to control fluid flow to the gun outlet , wherein the first trigger actuates a valve of the handheld fluid sprayer that controls the fluid flow; characterised in that the coupling mechanism comprises a pin configured to mechanically actuate the valve of the handheld fluid sprayer when the fluid hose is coupled to the handheld fluid sprayer. a gun inlet configured to couple to the fluid hose and receive the fluid from the handheld fluid sprayer ; a gun outlet configured to expel the fluid in a spray pattern; and a second trigger configured to control fluid flow to the gun outlet , wherein the first trigger actuates a valve of the handheld fluid sprayer that controls the fluid flow; characterised in that the coupling mechanism comprises a pin configured to mechanically actuate the valve of the handheld fluid sprayer when the fluid hose is coupled to the handheld fluid sprayer.
An antibody agent specific to Dengue virus, wherein the antibody agent binds to and neutralizes each of Dengue virus serotypes D1, D2 ,D3 and D4, which antibody agent comprises a heavy chain variable region and a light chain variable region, wherein the heavy chain framework region 1 (FR1), framework region 2 (FR2), framework region 3 (FR3), and framework region 4 (FR4) have more than 90% identity with SEQ ID NO: 3, SEQ ID NO: 4 ;SEQ ID NO: 5 and SEQ ID NO: 6, respectively and the light chain FR1, FR2, FR3 and FR4 have more than 90% sequence identity with SEQ ID NO:10; SEQ ID NO:11; SEQ ID NO:12 and SEQ ID NO:13 respectively, wherein the heavy chain variable region comprises a CDR1, a CDR2 and a CDR3 whose amino acid sequences are set forth in SEQ ID NO.: 23, SEQ ID NO.: 24, SEQ ID NO.: 25, respectively and the light chain variable region comprises a CDR1, a CDR2 and a CDR3 whose amino acid sequences are set forth in SEQ ID NO.: 26, SEQ ID NO.: 27 and SEQ ID NO.: 28, respectively..
An operating method for an electric heater, wherein the electric heater comprises: - at least one control unit with at least one temperature sensor measuring a reference temperature, and - at least one heating element having a PTC mode above a critical temperature and a NTC mode below the critical temperature; wherein - a fluid passing the electric heater is heated to an outlet temperature by the heating element, - the electric heater being operated either in a normal mode or in a protection mode, - in the normal mode, the heating element is supplied with direct current and/or direct voltage, - in the protection mode, the electrical power supplied to the heating element is regulated by pulse width modulation, - the electric heater is operated in the normal mode if the reference temperature is less than or equal to the critical temperature, - the electric heater is operated in the protection mode if the reference temperature is greater than the critical temperature. - at least one control unit with at least one temperature sensor measuring a reference temperature, and - at least one heating element having a PTC mode above a critical temperature and a NTC mode below the critical temperature; wherein - a fluid passing the electric heater is heated to an outlet temperature by the heating element, - the electric heater being operated either in a normal mode or in a protection mode, - in the normal mode, the heating element is supplied with direct current and/or direct voltage, - in the protection mode, the electrical power supplied to the heating element is regulated by pulse width modulation, - the electric heater is operated in the normal mode if the reference temperature is less than or equal to the critical temperature, - the electric heater is operated in the protection mode if the reference temperature is greater than the critical temperature.
A method for in vitro diagnosing infection by a Mycobacterium species in a subject, said method comprising incubating a blood sample comprising lymphocytes from said subject in the presence of at least one biomarker selected from the list consisting of: (i) protein Rv3239c, derived from a Mycobacterium species or related organism and comprising at least one T-cell epitope; (ii) an homolog of the protein Rv3239c having an amino acid sequence with at least 80% similarity to the protein Rv3239c after optimal alignment; and (iii) a peptide fragment of the protein as defined in (i) or (ii), the peptide fragment comprising or consisting of an amino acid sequence selected from PDLRGALLLAVTLGLVT (SEQ ID NO:54), PDWGWLSVATVGSFLA (SEQ ID NO:55), GAVLGVAVMVILIGKPEHGTA (SEQ ID NO:56), AAICFIAVAVAAAVL (SEQ ID NO:57), TKLVRLTKAQFDEIA (SEQ ID NO:58), ADLVLAGPAASREH (SEQ ID NO:59), YAYEYFIRHNPLSDYA (SEQ ID NO:60), and FPVRGLVRGRRTLTLLEA (SEQ ID NO:61); for a time and under conditions sufficient to stimulate the lymphocytes to produce an effector molecule, wherein the presence or level of the effector molecule is indicative of the lymphocytes derived from a subject infected with or prior exposed to the Mycobacterium species. (i) protein Rv3239c, derived from a Mycobacterium species or related organism and comprising at least one T-cell epitope; (ii) an homolog of the protein Rv3239c having an amino acid sequence with at least 80% similarity to the protein Rv3239c after optimal alignment; and (iii) a peptide fragment of the protein as defined in (i) or (ii), the peptide fragment comprising or consisting of an amino acid sequence selected from PDLRGALLLAVTLGLVT (SEQ ID NO:54), PDWGWLSVATVGSFLA (SEQ ID NO:55), GAVLGVAVMVILIGKPEHGTA (SEQ ID NO:56), AAICFIAVAVAAAVL (SEQ ID NO:57), TKLVRLTKAQFDEIA (SEQ ID NO:58), ADLVLAGPAASREH (SEQ ID NO:59), YAYEYFIRHNPLSDYA (SEQ ID NO:60), and FPVRGLVRGRRTLTLLEA (SEQ ID NO:61);
A dressing, comprising: a first foam layer having a pore density in a range between approximately 35.4 pores per cm (90 pores per inch) and approximately 141.7 pores per cm (360 pores per inch); a superabsorbent material deposited on the first foam layer; and a second foam layer having a pore density in a range between approximately 35.4 pores per cm (90 pores per inch) and approximately 141.7 pores per cm (360 pores per inch); wherein the superabsorbent material is confined between the first foam layer and the second foam layer. a first foam layer having a pore density in a range between approximately 35.4 pores per cm (90 pores per inch) and approximately 141.7 pores per cm (360 pores per inch); a superabsorbent material deposited on the first foam layer; and a second foam layer having a pore density in a range between approximately 35.4 pores per cm (90 pores per inch) and approximately 141.7 pores per cm (360 pores per inch); wherein the superabsorbent material is confined between the first foam layer and the second foam layer.
Housing-free electric traction machine , comprising a stator constructed from a stator laminated core , and a rotor shaft having a rotor which is constructed from a rotor laminated core and secured on said shaft, wherein the stator laminated core is arranged between two outer press plates and at least one bearing shield having a bearing for the rotor shaft in each case, and tension strips are arranged between the press plates , wherein, along part of the circumference of the stator laminated core between the press plates , at least two cooling bodies each having at least one cooling channel for guiding a cooling fluid are arranged opposite one another on the surface of the stator laminated core such that the housing-free electric traction machine has a smaller height (h) relative to its width (b), wherein each cooling body is connected to at least one tension strip and/or the press plates and/or the stator laminated core by securing screws or other securing members, characterized in that the cooling channels are provided for guiding a cooling liquid, and in that the press plates are substantially rectangular and the stator laminated core is substantially square.
A three-dimensional memory device , comprising: a memory array structure ; and a staircase structure (102, 202-1, 202-2) in an intermediate of the memory array structure and dividing the memory array structure into a first memory array structure (104-1) and a second memory array structure (104-2) along a first lateral direction, the staircase structure (102, 202-1, 202-2) comprising (i) a plurality of stairs extending along the first lateral direction, and (ii) a bridge structure in contact with the first memory array structure (104-1) and the second memory array structure (104-2), each of the plurality of stairs comprising a stair above one or more pairs of dielectric layers, wherein each stair comprises a respective conductor portion on a top surface of the stair and in contact with and electrically connected to a respective conductive layer at the same level of the bridge structure , and a dielectric portion at a same level and in contact with the conductor portion , the stair being electrically connected to at least one of the first memory array structure (104-1) and the second memory array structure (104-2) through the respective conductive layer in the bridge structure ; and wherein a width (d) of conductor portion first decreases and then stays unchanged along a second lateral direction perpendicular to the first lateral direction and away from the bridge structure. a memory array structure ; and a staircase structure (102, 202-1, 202-2) in an intermediate of the memory array structure and dividing the memory array structure into a first memory array structure (104-1) and a second memory array structure (104-2) along a first lateral direction, the staircase structure (102, 202-1, 202-2) comprising (i) a plurality of stairs extending along the first lateral direction, and (ii) a bridge structure in contact with the first memory array structure (104-1) and the second memory array structure (104-2), each of the plurality of stairs comprising a stair above one or more pairs of dielectric layers, wherein each stair comprises a respective conductor portion on a top surface of the stair and in contact with and electrically connected to a respective conductive layer at the same level of the bridge structure , and a dielectric portion at a same level and in contact with the conductor portion , the stair being electrically connected to at least one of the first memory array structure (104-1) and the second memory array structure (104-2) through the respective conductive layer in the bridge structure ; and wherein a width (d) of conductor portion first decreases and then stays unchanged along a second lateral direction perpendicular to the first lateral direction and away from the bridge structure.
A process for the production of yogurt, comprising fermenting milk with lactic acid bacteria and contacting milk with a polypeptide having chymosin activity having a clotting activity divided by proteolytic activity (C/P ratio) higher than the C/P ratio of bovine chymosin and wherein the polypeptide having chymosin activity has an amino acid sequence which; a. when aligned with the chymosin comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue corresponding to amino acid 51 and/or 221 and wherein the polypeptide having chymosin activity shares at least about 90% sequence identity with a polypeptide according to SEQ ID NO: 2; and/or b. when aligned with SEQ ID NO: 4 comprises at least one substitution of an amino acid residue located in the S2 binding pocket, and wherein an amino acid residue located in the S2 binding pocket corresponds to position 219, 223, 288, 290, 295 or 297 when aligned with SEQ ID NO: 4, and wherein the polypeptide having chymosin activity shares at least about 90% sequence identity with a polypeptide according to SEQ ID NO: 4. a. when aligned with the chymosin comprising the sequence set out in SEQ ID NO: 2, comprises at least one substitution of an amino acid residue corresponding to amino acid 51 and/or 221 and wherein the polypeptide having chymosin activity shares at least about 90% sequence identity with a polypeptide according to SEQ ID NO: 2; and/or b. when aligned with SEQ ID NO: 4 comprises at least one substitution of an amino acid residue located in the S2 binding pocket, and wherein an amino acid residue located in the S2 binding pocket corresponds to position 219, 223, 288, 290, 295 or 297 when aligned with SEQ ID NO: 4, and wherein the polypeptide having chymosin activity shares at least about 90% sequence identity with a polypeptide according to SEQ ID NO: 4.
An integrated circuit, wherein the integrated circuit is configured to control steps of a process of a user equipment for being scheduled with uplink radio resources, wherein at least one unlicensed cell is configured for communication between the user equipment and a radio base station that is responsible for scheduling uplink radio resources on the unlicensed cell, wherein the steps of the process comprise: receiving (S102) from the radio base station a first-stage uplink resource scheduling message indicating uplink radio resources usable by the user equipment to perform an uplink transmission via the unlicensed cell, receiving (S103) from the radio base station a second-stage uplink resource scheduling message, which is related to the first-stage uplink resource scheduling message, determining (S104) whether the first-stage uplink resource scheduling message is valid or not determining, when receiving the second-stage uplink resource scheduling message, that the uplink transmission is scheduled in case the process has determined that the first-stage uplink resource scheduling message is valid, wherein the determination if the first-stage uplink resource scheduling message is valid is based on a determination as to whether the uplink transmission has been triggered by another second-stage uplink resource scheduling message within a predetermined time period prior to reception of the second-stage uplink resource scheduling message, and in case the process has determined that the uplink transmission is scheduled, performing (S107) the uplink transmission via the unlicensed cell. receiving (S102) from the radio base station a first-stage uplink resource scheduling message indicating uplink radio resources usable by the user equipment to perform an uplink transmission via the unlicensed cell, receiving (S103) from the radio base station a second-stage uplink resource scheduling message, which is related to the first-stage uplink resource scheduling message, determining (S104) whether the first-stage uplink resource scheduling message is valid or not determining, when receiving the second-stage uplink resource scheduling message, that the uplink transmission is scheduled in case the process has determined that the first-stage uplink resource scheduling message is valid, wherein the determination if the first-stage uplink resource scheduling message is valid is based on a determination as to whether the uplink transmission has been triggered by another second-stage uplink resource scheduling message within a predetermined time period prior to reception of the second-stage uplink resource scheduling message, and in case the process has determined that the uplink transmission is scheduled, performing (S107) the uplink transmission via the unlicensed cell.
A manual pulling instrument, in particular an accordion, comprising: a first housing part comprising operating elements which are configured to be operated by a player of the manual pulling instrument with one hand; a second housing part ; and a bellows by which the first housing part and the second housing part are movably connected to each other; wherein the operating elements occupy a spatial area extending to a first boundary line on a first side and to a second boundary line on a second side opposite the first side, wherein the second boundary line is further away from the bellows than the first boundary line , and wherein the second boundary line has a concave curvature, and wherein the spatial area occupied by the operating elements extends in a plane (T) which encloses an angle (α) of between 20° and 65°, preferably between 30° and 60°, with a center plane (M) of the manual pulling instrument which extends symmetrically with respect to the bellows between the first housing part and the second housing part when the bellows is in a folded state, wherein the first housing part comprises a rear surface area configured to face the torso of the player, characterized in that an upper end of the spatial area occupied by the operating elements is formed further away from the rear surface area than a lower end of the spatial area. a first housing part comprising operating elements which are configured to be operated by a player of the manual pulling instrument with one hand; a second housing part ; and a bellows by which the first housing part and the second housing part are movably connected to each other; wherein the operating elements occupy a spatial area extending to a first boundary line on a first side and to a second boundary line on a second side opposite the first side, wherein the second boundary line is further away from the bellows than the first boundary line , and wherein the second boundary line has a concave curvature, and wherein the spatial area occupied by the operating elements extends in a plane (T) which encloses an angle (α) of between 20° and 65°, preferably between 30° and 60°, with a center plane (M) of the manual pulling instrument which extends symmetrically with respect to the bellows between the first housing part and the second housing part when the bellows is in a folded state, wherein the first housing part comprises a rear surface area configured to face the torso of the player, characterized in that an upper end of the spatial area occupied by the operating elements is formed further away from the rear surface area than a lower end of the spatial area.