A flexible planar patch for multiplex detection of analytes, comprising a. a capture layer having a proximal surface and a distal surface , wherein said capture layer is characterized by a thickness of 10 μm to 2 mm, and wherein said capture layer comprises i. an analyte capture zone extending from said proximal surface to said distal surface , said analyte capture zone consisting of a first water permeable material, said first water permeable material comprising a ligand capable of binding specifically to an analyte, wherein said analyte capture zone is compartmentalized into a plurality of confined water permeable capture divisions , wherein each of said capture divisions comprises said ligand capable of binding specifically to an analyte and is separated by a first divider that is impermeable to water; and ii. a fastener zone which is impermeable to water and/or delimited from said analyte capture zone by a water impermeable barrier zone , said fastener zone comprising, on said proximal surface , an adhesive capable of fastening said capture layer removably to a surface, and b. a cover layer having a proximal surface and a distal surface , said cover layer comprising, on said proximal surface , an adhesive capable of fastening said cover layer removably to said capture layer . a. a capture layer having a proximal surface and a distal surface , wherein said capture layer is characterized by a thickness of 10 μm to 2 mm, and wherein said capture layer comprises i. an analyte capture zone extending from said proximal surface to said distal surface , said analyte capture zone consisting of a first water permeable material, said first water permeable material comprising a ligand capable of binding specifically to an analyte, wherein said analyte capture zone is compartmentalized into a plurality of confined water permeable capture divisions , wherein each of said capture divisions comprises said ligand capable of binding specifically to an analyte and is separated by a first divider that is impermeable to water; and ii. a fastener zone which is impermeable to water and/or delimited from said analyte capture zone by a water impermeable barrier zone , said fastener zone comprising, on said proximal surface , an adhesive capable of fastening said capture layer removably to a surface, and i. an analyte capture zone extending from said proximal surface to said distal surface , said analyte capture zone consisting of a first water permeable material, said first water permeable material comprising a ligand capable of binding specifically to an analyte, wherein said analyte capture zone is compartmentalized into a plurality of confined water permeable capture divisions , wherein each of said capture divisions comprises said ligand capable of binding specifically to an analyte and is separated by a first divider that is impermeable to water; and ii. a fastener zone which is impermeable to water and/or delimited from said analyte capture zone by a water impermeable barrier zone , said fastener zone comprising, on said proximal surface , an adhesive capable of fastening said capture layer removably to a surface, and b. a cover layer having a proximal surface and a distal surface , said cover layer comprising, on said proximal surface , an adhesive capable of fastening said cover layer removably to said capture layer . <EOS>