mhurhangee/patent-ind-claim-en huggingface dataset:
Apparatus for the automated management of the assembly of a machine for processing and/or packaging pharmaceutical products inside a clean room , comprising: - a chamber delimited by walls , at least one of said walls being provided with at least one access aperture which can be selectively closed by means of a primary closing unit ; - a processing system for processing the pharmaceutical products comprising at least one modular assemblable element , which can be removably coupled to other elements to obtain said processing system, said processing system being housed in said chamber ; - a transport container configured to be associated with said access aperture from the outside of said chamber and provided with a secondary closing unit able to cooperate with the primary closing unit of said chamber so that they can be opened in order to put the inside of the transport container in communication with the inside of the chamber , said transport container being configured to contain said at least one modular assemblable element that has to be coupled to other elements to obtain said processing system , said apparatus being characterized in that it comprises a handling device housed in said chamber and comprising a mobile work tool configured to alternately grip or release said assemblable element to respectively remove it from said transport container and assemble it in a predeterminate position in order to couple it to other elements so as to obtain said processing system and/or de-couple it from said other elements with which it forms said processing system and return it into said transport container . - a chamber delimited by walls , at least one of said walls being provided with at least one access aperture which can be selectively closed by means of a primary closing unit ; - a processing system for processing the pharmaceutical products comprising at least one modular assemblable element , which can be removably coupled to other elements to obtain said processing system, said processing system being housed in said chamber ; - a transport container configured to be associated with said access aperture from the outside of said chamber and provided with a secondary closing unit able to cooperate with the primary closing unit of said chamber so that they can be opened in order to put the inside of the transport container in communication with the inside of the chamber , said transport container being configured to contain said at least one modular assemblable element that has to be coupled to other elements to obtain said processing system , said apparatus being characterized in that it comprises a handling device housed in said chamber and comprising a mobile work tool configured to alternately grip or release said assemblable element to respectively remove it from said transport container and assemble it in a predeterminate position in order to couple it to other elements so as to obtain said processing system and/or de-couple it from said other elements with which it forms said processing system and return it into said transport container .
Use of b) a calcium alkylsalicylate detergent in an amount of 0.1 to 1 wt.% in terms of a sulfated ash content, the calcium alkylsalicylate detergent having a sulfur content of not more than 3 wt.% and a total base number in the range of 10 to 350 mg KOH/g, containing an organic acid calcium salt under the condition that the lubricating oil composition contains the organic acid calcium salt in an amount of 0.2 to 7 wt.% based on the amount of the oil composition, and comprising an unsulfurized calcium alkylsalicylate detergent having an alkyl group having 14 to 18 carbon atoms, in a lubricating oil composition for lubricating an internal combustion engine which is operated by the use of a fuel oil having a sulfur content of not more than 0.005 wt.%, to improve high temperature detergency at temperatures of 300°C or greater as determined in accordance with the hot tube test (KES-07-803), wherein the lubricating oil composition comprises the following components a), c) and d), along with b), dissolved or dispersed in a base oil having a sulfur content of not more than 0.1 wt.% and has a sulfated ash content in a range of 0.1 to 1.1 wt.%, a phosphorus content in a range of 0.01 to 0.12 wt.%, a sulfur content in a range of 0.01 to 0.5 wt.% and a chlorine content of not more than 150 ppm: a) an ashless dispersant in an amount of 0.01 to 0.3 wt.% in terms of a nitrogen content, the ashless dispersant being selected from the group consisting of an alkenyl succinimide and an alkyl succinimide; c) a zinc phosphate anti-wear agent in an amount of 0.01 to 0.12 wt.% in terms of a phosphorus content, the zinc phosphate being selected from the group consisting of a zinc dialkyldithiophosphate and a zinc dihydrocarbylphosphate, and d) an oxidation inhibitor in an amount of 0.01 to 5 wt.%, the oxidation inhibitor being selected from the group consisting of an oxidation inhibiting phenol compound and an oxidation inhibiting amine compound, wherein the sulfated ash content, phosphorus content, sulfur content, and the wt.% given in a) to d) above are values based on the amount of the lubricating oil composition. a) an ashless dispersant in an amount of 0.01 to 0.3 wt.% in terms of a nitrogen content, the ashless dispersant being selected from the group consisting of an alkenyl succinimide and an alkyl succinimide; c) a zinc phosphate anti-wear agent in an amount of 0.01 to 0.12 wt.% in terms of a phosphorus content, the zinc phosphate being selected from the group consisting of a zinc dialkyldithiophosphate and a zinc dihydrocarbylphosphate, and d) an oxidation inhibitor in an amount of 0.01 to 5 wt.%, the oxidation inhibitor being selected from the group consisting of an oxidation inhibiting phenol compound and an oxidation inhibiting amine compound,
A filter device , comprising: a filter comprising a substrate made of a dielectric, a pair of wide walls being constituted by a first conductor layer and a second conductor layer , respectively, and covering respective opposite surfaces of the substrate , and narrow walls being constituted by post walls which are provided inside the substrate ; and a first waveguide tube and a second waveguide tube each including a tube wall made of a conductor and being placed along the substrate , the filter further comprising: a first columnar conductor passing through a first opening (13a1) which is provided in the first conductor layer , the first columnar conductor having one end portion located inside the substrate , a second columnar conductor passing through a second opening (13a2) which is provided in the first conductor layer or the second conductor layer , the second columnar conductor having one end portion located inside the substrate , the first waveguide tube being placed such that the first columnar conductor passes through an opening which is provided in the tube wall of the first waveguide tube and such that another end portion of the first columnar conductor is located inside the first waveguide tube , the second waveguide tube being placed such that the second columnar conductor passes through an opening which is provided in the tube wall of the second waveguide tube and such that another end portion of the second columnar conductor is located inside the second waveguide tube , wherein the filter further comprises one or more partition walls being constituted by post walls provided inside the substrate and dividing a region surrounded by the pair of wide walls and the narrow walls into a plurality of resonators (11a to 11d), the one or more partition walls having respective coupling windows . a first columnar conductor passing through a first opening (13a1) which is provided in the first conductor layer , the first columnar conductor having one end portion located inside the substrate , a second columnar conductor passing through a second opening (13a2) which is provided in the first conductor layer or the second conductor layer , the second columnar conductor having one end portion located inside the substrate , the first waveguide tube being placed such that the first columnar conductor passes through an opening which is provided in the tube wall of the first waveguide tube and such that another end portion of the first columnar conductor is located inside the first waveguide tube , the second waveguide tube being placed such that the second columnar conductor passes through an opening which is provided in the tube wall of the second waveguide tube and such that another end portion of the second columnar conductor is located inside the second waveguide tube , wherein the filter further comprises one or more partition walls being constituted by post walls provided inside the substrate and dividing a region surrounded by the pair of wide walls and the narrow walls into a plurality of resonators (11a to 11d), the one or more partition walls having respective coupling windows .
Method for detecting an obstacle in the surrounding region of a motor vehicle , in which the following steps are carried out by an evaluation device of the motor vehicle : - receiving ultrasonic sensor data from at least one ultrasonic sensor of the motor vehicle and at least one camera image from at least one camera of the motor vehicle , - detecting the obstacle and determining a position of the obstacle using the ultrasonic sensor data, - verifying the obstacle detected using the ultrasonic sensor data by way of the at least one camera image, characterized by the steps of: - determining a first free space by evaluating the at least one camera image with respect to a first criterion and determining a second free space by evaluating the at least one camera image with respect to a second criterion, wherein an obstacle-free partial region in the surrounding region is described by the free spaces , - determining a first spatial boundary of the first free space and a second spatial boundary of the second free space , wherein values of the first spatial boundary and of the second spatial boundary are determined within those partial capturing regions of the capturing region of the at least one camera in which detection points of an ultrasonic sensor are present, - verifying the obstacle if the first spatial boundary and the second spatial boundary deviate from one another at most by a predetermined threshold value and each of the first and second boundaries deviate from the position at most by the predetermined threshold value. - receiving ultrasonic sensor data from at least one ultrasonic sensor of the motor vehicle and at least one camera image from at least one camera of the motor vehicle , - detecting the obstacle and determining a position of the obstacle using the ultrasonic sensor data, - verifying the obstacle detected using the ultrasonic sensor data by way of the at least one camera image, - determining a first free space by evaluating the at least one camera image with respect to a first criterion and determining a second free space by evaluating the at least one camera image with respect to a second criterion, wherein an obstacle-free partial region in the surrounding region is described by the free spaces , - determining a first spatial boundary of the first free space and a second spatial boundary of the second free space , wherein values of the first spatial boundary and of the second spatial boundary are determined within those partial capturing regions of the capturing region of the at least one camera in which detection points of an ultrasonic sensor are present, - verifying the obstacle if the first spatial boundary and the second spatial boundary deviate from one another at most by a predetermined threshold value and each of the first and second boundaries deviate from the position at most by the predetermined threshold value.
A system comprising: a photoplethysmogram, PPG, sensor disposed on an in-ear earpiece , the PPG sensor configured to measure signals from an ear of a subject wearing the in-ear earpiece , wherein the in-ear earpiece comprises: an earbud housing an acoustic driver module, a body substantially elliptical or circular in shape and coupled to the earbud, a positioning and retaining structure and a nozzle extending from the body towards a substantially frusto-conical sealing structure , the nozzle extending toward an ear canal of the subject and including an acoustic passage to conduct sound waves to the ear canal of the subject, wherein a light emitting diode, LED, and a photodetector, PD, included in the PPG sensor are housed on or inside the nozzle; and at least one processor; instructions, stored in a memory, that cause the at least one processor to: determine a sleep stage of the subject based, at least in part, on the signals; and provide an output based on the determined sleep stage. a photoplethysmogram, PPG, sensor disposed on an in-ear earpiece , the PPG sensor configured to measure signals from an ear of a subject wearing the in-ear earpiece , wherein the in-ear earpiece comprises: an earbud housing an acoustic driver module, a body substantially elliptical or circular in shape and coupled to the earbud, a positioning and retaining structure and a nozzle extending from the body towards a substantially frusto-conical sealing structure , the nozzle extending toward an ear canal of the subject and including an acoustic passage to conduct sound waves to the ear canal of the subject, wherein a light emitting diode, LED, and a photodetector, PD, included in the PPG sensor are housed on or inside the nozzle; and at least one processor; instructions, stored in a memory, that cause the at least one processor to: determine a sleep stage of the subject based, at least in part, on the signals; and provide an output based on the determined sleep stage. determine a sleep stage of the subject based, at least in part, on the signals; and provide an output based on the determined sleep stage.
A method for determining a functional significance of coronary artery stenosis comprising: performing a cardiac computed tomography scan of a patient or a computed tomography angiography scan of a patient; determining, based on the scan, a mathematical relationship between a spatial dispersion of contrast in the coronary artery of the patient (TAG, TCG) and a temporal contrast dispersion of an arterial input function of the patient; calculating the coronary flow velocity (CFV) within the coronary artery from the mathematical relationship; calculating an estimate of the pressure gradient (PG) within the coronary artery using the coronary flow velocity, the arterial input function and information on the coronary luminal area, position and location within the artery; and using the PG to determine the functional significance of the coronary artery stenosis. performing a cardiac computed tomography scan of a patient or a computed tomography angiography scan of a patient; determining, based on the scan, a mathematical relationship between a spatial dispersion of contrast in the coronary artery of the patient (TAG, TCG) and a temporal contrast dispersion of an arterial input function of the patient; calculating the coronary flow velocity (CFV) within the coronary artery from the mathematical relationship; calculating an estimate of the pressure gradient (PG) within the coronary artery using the coronary flow velocity, the arterial input function and information on the coronary luminal area, position and location within the artery; and using the PG to determine the functional significance of the coronary artery stenosis.
An in vitro method for increasing targeted genome modification efficiency and/or specificity in a eukaryotic cell, the method comprising introducing into the eukaryotic cell a composition comprising: a. a CRISPR system having binding activity and double-stranded cleavage activity, or a nucleic acid encoding said CRISPR system, the CRISPR system comprising (i) a catalytically active Type II CRISPR/Cas9 protein or a catalytically active Type V CRISPR/Cpf1 protein, and (ii) a guide RNA; and b. at least one CRISPR system having binding activity but lacking cleavage activity, or a nucleic acid encoding said CRISPR system, the CRISPR system comprising (i) a catalytically inactive Type II CRISPR/Cas9 protein, and (ii) a guide RNA; and c. a donor polynucleotide comprising a donor sequence, wherein the CRISPR system (a) is targeted to a target chromosomal sequence and each of the at least one CRISPR system (b) is targeted to a site proximal to the target chromosomal sequence, and binding of the at least one CRISPR system (b) to the site proximal to the target chromosomal sequence increases accessibility of CRISPR system (a) to the target chromosomal sequence, thereby increasing efficiency and/or specificity of integration or exchange of the donor sequence with the target chromosomal sequence thereby modifying the genome in the eukaryotic cell. a. a CRISPR system having binding activity and double-stranded cleavage activity, or a nucleic acid encoding said CRISPR system, the CRISPR system comprising (i) a catalytically active Type II CRISPR/Cas9 protein or a catalytically active Type V CRISPR/Cpf1 protein, and (ii) a guide RNA; and b. at least one CRISPR system having binding activity but lacking cleavage activity, or a nucleic acid encoding said CRISPR system, the CRISPR system comprising (i) a catalytically inactive Type II CRISPR/Cas9 protein, and (ii) a guide RNA; and c. a donor polynucleotide comprising a donor sequence, wherein
Device for the aggregation of cells, wherein the device comprises at least one cavity for receiving one or more than one cell, wherein the cavity is a pyramid with a rounded tip and wherein the pyramid has rounded edges between the pyramid sidewalls.
Method of obtaining sound tuning layer that is polyethylene (PE) or polyethylene terephthalate (PET) based and obtained from the following steps: - sublimation of a PE or PET based starting material with an open cell structure, such sublimation comprising pressing a PE or PET based starting material under heat and pressure, against a sublimation transfer support, thereby obtaining a sublimated sound tuning layer, and characterised in that - subsequent cold pressing, said cold pressing being performed at a lower temperature as regards the sublimation step, and while the sublimated sound tuning layer is still hot, and thereby forming the sound tuning layer, maintaining said open cell structure. - sublimation of a PE or PET based starting material with an open cell structure, such sublimation comprising pressing a PE or PET based starting material under heat and pressure, against a sublimation transfer support, thereby obtaining a sublimated sound tuning layer, and characterised in that - subsequent cold pressing, said cold pressing being performed at a lower temperature as regards the sublimation step, and while the sublimated sound tuning layer is still hot, and thereby forming the sound tuning layer, maintaining said open cell structure.
A prosthetic device, comprising: a finger digit ; and a motor configured to move the finger digit based at least in part on one or more command signals received from a controller , wherein the controller is configured to: determine, based at least in part on a command signal, to move the finger digit , communicate a first command signal to alter a duty cycle of the motor to satisfy a first duty cycle level to overcome stiction associated with one or more components of the motor , and based at least in part on a determination that the duty cycle of the motor satisfies the first duty cycle level, communicate a second command signal to systematically increase the duty cycle of the motor over a predetermined duration of time to satisfy a second duty cycle level. a finger digit ; and a motor configured to move the finger digit based at least in part on one or more command signals received from a controller , wherein the controller is configured to: determine, based at least in part on a command signal, to move the finger digit , communicate a first command signal to alter a duty cycle of the motor to satisfy a first duty cycle level to overcome stiction associated with one or more components of the motor , and based at least in part on a determination that the duty cycle of the motor satisfies the first duty cycle level, communicate a second command signal to systematically increase the duty cycle of the motor over a predetermined duration of time to satisfy a second duty cycle level. determine, based at least in part on a command signal, to move the finger digit , communicate a first command signal to alter a duty cycle of the motor to satisfy a first duty cycle level to overcome stiction associated with one or more components of the motor , and based at least in part on a determination that the duty cycle of the motor satisfies the first duty cycle level, communicate a second command signal to systematically increase the duty cycle of the motor over a predetermined duration of time to satisfy a second duty cycle level.
Method for detecting biological objects by means of a surface plasmon resonance imaging detection system comprising: a functional surface having at least one sensitive site formed of ligands adapted to bind to biological objects; and an optical measurement device configured to generate surface plasmon resonance at the functional surface when the functional surface is exposed to a gas, and adapted to acquire an image of the sensitive site; the method comprising: ∘ an assimilation step, comprising exposing the functional surface to a sample of interest formed of an aqueous carrier liquid containing the biological objects, the biological objects thus binding to the ligands; ∘ a step of acquiring an image of the sensitive site using the optical measuring device ; ∘ a step of detecting the biological objects from the acquired image; ∘ the method being characterised in that it comprises a step, which is carried out between the assimilation step and the acquisition step, of removing the liquid in contact with the functional surface , and of exposing the functional surface to a gas not containing the biological objects, the biological objects remaining bound to the ligands, the acquisition step thus being carried out while the biological objects are bound to the ligands and while the gas is in contact with the functional surface . ∘ an assimilation step, comprising exposing the functional surface to a sample of interest formed of an aqueous carrier liquid containing the biological objects, the biological objects thus binding to the ligands; ∘ a step of acquiring an image of the sensitive site using the optical measuring device ; ∘ a step of detecting the biological objects from the acquired image; ∘ the method being characterised in that it comprises a step, which is carried out between the assimilation step and the acquisition step, of removing the liquid in contact with the functional surface , and of exposing the functional surface to a gas not containing the biological objects, the biological objects remaining bound to the ligands, the acquisition step thus being carried out while the biological objects are bound to the ligands and while the gas is in contact with the functional surface .