A method for processing, displaying and navigating breast tissue information, comprising: obtaining a plurality of tomosynthesis images (Tr) of a patient's breast, wherein the tomosynthesis images (Tr) are X,Y coordinate slices (Tr) at differing Z-axis locations of the breast, the images (Tr) have one or more corresponding X,Y coordinate locations; wherein the method comprises by the steps of: generating a synthesized 2D image (Ms) of the patient's breast only from the obtained plurality of tomosynthesis images (Tr), the synthesized 2D image (Ms) similar to that of a conventional 2D mammographic image (Mp), wherein generating the synthesized 2D image (Ms) comprises constructing a merged image (Imerge) by importing one or more regions from one or more of the plurality of tomosynthesis images (Tr) into the merged image (Imerge), in which the one or more regions imported into the merged image (Imerge) comprises at least a portion of one or more source tomosynthesis images (Tr) for that region, and wherein the regions are imported into the merged image (Imerge) at X,Y coordinate locations corresponding to the X,Y coordinate locations of the respective regions in their source image (Tr), wherein each image of the plurality of tomosynthesis images (Tr) contains one or more regions defined by their X,Y coordinate locations that are common for all images (Tr) of the plurality, and wherein one of each said common region is imported from the plurality of images into the merged image based upon a comparison of one or more attributes of the respective common region of each image (Tr); displaying the synthesized 2D image (Ms); receiving a user indication of a region of interest in the synthesized 2D image (Ms); and displaying at least the portion of one or more source tomosynthesis images (Tr). generating a synthesized 2D image (Ms) of the patient's breast only from the obtained plurality of tomosynthesis images (Tr), the synthesized 2D image (Ms) similar to that of a conventional 2D mammographic image (Mp), wherein generating the synthesized 2D image (Ms) comprises constructing a merged image (Imerge) by importing one or more regions from one or more of the plurality of tomosynthesis images (Tr) into the merged image (Imerge), in which the one or more regions imported into the merged image (Imerge) comprises at least a portion of one or more source tomosynthesis images (Tr) for that region, and wherein the regions are imported into the merged image (Imerge) at X,Y coordinate locations corresponding to the X,Y coordinate locations of the respective regions in their source image (Tr), wherein each image of the plurality of tomosynthesis images (Tr) contains one or more regions defined by their X,Y coordinate locations that are common for all images (Tr) of the plurality, and wherein one of each said common region is imported from the plurality of images into the merged image based upon a comparison of one or more attributes of the respective common region of each image (Tr); displaying the synthesized 2D image (Ms); receiving a user indication of a region of interest in the synthesized 2D image (Ms); and displaying at least the portion of one or more source tomosynthesis images (Tr). <EOS>