mhurhangee/patent-ind-claim-en huggingface dataset:
A method of manufacturing a highly glycosylated human chorionic gonadotropin carboxy terminal peptide (CTP)-modified human growth hormone (hGH) polypeptide, said polypeptide consisting of two CTPs attached to the carboxy terminus of the hGH and one CTP attached to the amino terminus of the hGH, wherein the amino acid sequence of said polypeptide is set forth in SEQ ID NO: 7, and wherein the highly glycosylated CTP-modified hGH is glycosylated at between 12 and 18 O-linked glycosylation sites, the method comprising the steps of: (a) stably transfecting a predetermined number of cells with an expression vector comprising a coding portion encoding said CTP-modified hGH, wherein said transfected cell expresses and secretes said CTP-modified hGH; (b) obtaining cell clones that overexpress said CTP-modified hGH; (c) expanding said clones in solution to a predetermined scale by culturing at a dissolved oxygen (DO) content of 20-30%; (d) harvesting said solution containing said clones; (e) filtering said solution containing said clones to obtain a clarified harvest solution; and, (f) purifying said clarified harvest solution to obtain a purified protein solution of the CTP-modified hGH, wherein at least 60% of the purified CTP-modified hGH in the clarified harvest is the highly glycosylated form of the CTP-modified hGH; thereby manufacturing a highly glycosylated CTP-modified hGH. (a) stably transfecting a predetermined number of cells with an expression vector comprising a coding portion encoding said CTP-modified hGH, wherein said transfected cell expresses and secretes said CTP-modified hGH; (b) obtaining cell clones that overexpress said CTP-modified hGH; (c) expanding said clones in solution to a predetermined scale by culturing at a dissolved oxygen (DO) content of 20-30%; (d) harvesting said solution containing said clones; (e) filtering said solution containing said clones to obtain a clarified harvest solution; and, (f) purifying said clarified harvest solution to obtain a purified protein solution of the CTP-modified hGH, wherein at least 60% of the purified CTP-modified hGH in the clarified harvest is the highly glycosylated form of the CTP-modified hGH;
Method for producing a coated steel strip for producing tailored blanks suitable for thermomechanical shaping comprising the following steps: providing a hot-rolled steel strip; coating the strip with a metallic coating; characterized in that , after the step of coating the strip, cold rolling the strip such that the strip obtains a variable thickness in its length direction, having at least thicker sections, thinner sections and transitional sections between the thicker and thinner sections, with the thinner sections being at least 15 % thinner than a thickness of the thicker sections. providing a hot-rolled steel strip; coating the strip with a metallic coating; characterized in that , after the step of coating the strip, cold rolling the strip such that the strip obtains a variable thickness in its length direction, having at least thicker sections, thinner sections and transitional sections between the thicker and thinner sections, with the thinner sections being at least 15 % thinner than a thickness of the thicker sections.
A method of controlling device-to-device, D2D, communication, the method comprising: a wireless communication device (10; 1300; 1500; 1800) determining a Discontinuous Reception, DRX, configuration for D2D communication; the wireless communication device (10; 1300; 1500; 1800) aligning the DRX configuration with a further wireless communication device (10; 1300; 1500; 1800); and based on the DRX configuration, the wireless communication device (10; 1300; 1500; 1800) participating in D2D communication with the further wireless communication device (10; 1300; 1500; 1800), wherein said aligning of the DRX configuration comprises: the wireless communication device (10; 1300; 1500; 1800) determining configuration information for at least a part of the DRX configuration; the wireless communication device (10; 1300; 1500; 1800) indicating the determined configuration information to the further wireless communication device (10; 1300; 1500; 1800); and in response to said indicating the determined configuration information, the wireless communication device (10; 1300; 1500; 1800) receiving acknowledgement information indicating whether the determined configuration information is accepted. a wireless communication device (10; 1300; 1500; 1800) determining a Discontinuous Reception, DRX, configuration for D2D communication; the wireless communication device (10; 1300; 1500; 1800) aligning the DRX configuration with a further wireless communication device (10; 1300; 1500; 1800); and based on the DRX configuration, the wireless communication device (10; 1300; 1500; 1800) participating in D2D communication with the further wireless communication device (10; 1300; 1500; 1800), wherein said aligning of the DRX configuration comprises: the wireless communication device (10; 1300; 1500; 1800) determining configuration information for at least a part of the DRX configuration; the wireless communication device (10; 1300; 1500; 1800) indicating the determined configuration information to the further wireless communication device (10; 1300; 1500; 1800); and in response to said indicating the determined configuration information, the wireless communication device (10; 1300; 1500; 1800) receiving acknowledgement information indicating whether the determined configuration information is accepted. the wireless communication device (10; 1300; 1500; 1800) determining configuration information for at least a part of the DRX configuration; the wireless communication device (10; 1300; 1500; 1800) indicating the determined configuration information to the further wireless communication device (10; 1300; 1500; 1800); and in response to said indicating the determined configuration information, the wireless communication device (10; 1300; 1500; 1800) receiving acknowledgement information indicating whether the determined configuration information is accepted.
A crosslinked metallocene-catalyzed polyethylene copolymer having a higher molecular weight (HMW) component and lower molecular weight (LMW) component wherein the HMW component is present in an amount of from 10 wt.% to 30 wt.% and wherein the LMW component is present in an amount of from 70 wt.% to 90 wt.%, the copolymer when tested in accordance with ASTM D1238 under a force of 21.6 kg having a high load melt index of from 6 g/10 min to 25 g/10 min and having gels present in an amount of less than 3230/m 2 (300/sq. ft.), wherein the gels have a size greater than 200 microns.
A paint composition comprising: a. a carrier liquid; b. at least about 10% by weight of pigment having a minimum fineness of grind by Hegman gauge of 4 to 5; c. a latex binder polymer having a compatibility score of 0.7 or lower, wherein the compatibility of the binder is determined as described in the specification herein; and d. a quaternary ammonium compound. a. a carrier liquid; b. at least about 10% by weight of pigment having a minimum fineness of grind by Hegman gauge of 4 to 5; c. a latex binder polymer having a compatibility score of 0.7 or lower, wherein the compatibility of the binder is determined as described in the specification herein; and d. a quaternary ammonium compound.
Method for determining a sulfur trioxide content in a gas , in which a sample of the gas is taken and a gas pressure of the sample is reduced, and with a wave number tunable monochrome light source a wave number resolved transmission measurement is carried out on the sample and from the measurement a sulfur trioxide content is derived, characterized in that the measurement takes place in the sulfur trioxide absorption band between 1360 and 1410 cm -1 , characterized in that the measurement takes place in a window around the sulfur trioxide absorption at 1365.49 cm -1 , using this sulfur trioxide absorption.
A quick connect refill friction stir spot welding tool , comprising: a clamp ; a friction sleeve located coaxially within the clamp ; a friction pin located coaxially within the clamp and friction sleeve ; and characterized by : wherein the clamp comprises a first radially-projecting mounting tab configured for engaging a first mounting slot in a clamp receiver of a refill friction stir spot welding weld head ; wherein the friction sleeve comprises a second radially-projecting mounting tab configured for engaging a second mounting slot in a spindle of the refill friction stir spot welding weld head , wherein the second radially-projecting mounting tab is located at a different axial location along an axis of the tool than the first radially-projecting mounting tab , and radially inward thereof; and wherein the clamp is attachable to and detachable from the refill friction stir spot welding weld head by rotations of the clamp through less than 360 degrees, and wherein the friction sleeve is attachable to and detachable from the refill friction stir spot welding weld head by rotations of the friction sleeve through less than 360 degrees. a clamp ; a friction sleeve located coaxially within the clamp ; a friction pin located coaxially within the clamp and friction sleeve ; and characterized by : wherein the clamp comprises a first radially-projecting mounting tab configured for engaging a first mounting slot in a clamp receiver of a refill friction stir spot welding weld head ; wherein the friction sleeve comprises a second radially-projecting mounting tab configured for engaging a second mounting slot in a spindle of the refill friction stir spot welding weld head , wherein the second radially-projecting mounting tab is located at a different axial location along an axis of the tool than the first radially-projecting mounting tab , and radially inward thereof; and wherein the clamp is attachable to and detachable from the refill friction stir spot welding weld head by rotations of the clamp through less than 360 degrees, and wherein the friction sleeve is attachable to and detachable from the refill friction stir spot welding weld head by rotations of the friction sleeve through less than 360 degrees. wherein the clamp comprises a first radially-projecting mounting tab configured for engaging a first mounting slot in a clamp receiver of a refill friction stir spot welding weld head ; wherein the friction sleeve comprises a second radially-projecting mounting tab configured for engaging a second mounting slot in a spindle of the refill friction stir spot welding weld head , wherein the second radially-projecting mounting tab is located at a different axial location along an axis of the tool than the first radially-projecting mounting tab , and radially inward thereof; and wherein the clamp is attachable to and detachable from the refill friction stir spot welding weld head by rotations of the clamp through less than 360 degrees, and wherein the friction sleeve is attachable to and detachable from the refill friction stir spot welding weld head by rotations of the friction sleeve through less than 360 degrees.
A ballast sweeping installation for picking up and distributing ballast located on a track, consisting of a sweeping brush rotatable about an axis of rotation , a ballast conveyor belt arranged preceding the same with regard to a brush rotation direction and having a transport direction extending parallel to the axis of rotation , and with a ballast guiding plate positioned between the sweeping brush and ballast conveyor belt for passing the ballast on to the ballast conveyor belt , characterized in that a length of the ballast conveyor belt delimited by two deflection ends is designed to be shorter than a length of the sweeping brush extending in the axis of rotation , and that the ballast conveyor belt is designed to be displaceable in the transport direction relative to the sweeping brush by means of a drive and that the length of the ballast conveyor belt is designed to correspond approximately to a gauge of the track .
A server computing device configured to execute a coordination agent to automatically provide remote access to one or more serial port interfaces of one or more virtual machines of a cloud application , the server computing device comprising: a determination module for determining an Internet Protocol, IP, address of a Virtual Serial Port Concentrator, VSPC, module deployed with the one or more virtual machines within the cloud application and that is specific to the cloud application ; a coupling module for causing a serial port interface of each of the one or more virtual machines to be communicatively coupled with the VSPC module ; an acquisition module for acquiring, from the VSPC module , one or more port numbers of the VSPC module that are associated with the one or more virtual machines , wherein each of the one or more port numbers can be used to remotely access the serial port interface of the corresponding virtual machine through the VSPC module ; and a providing module for causing the one or more port numbers and the IP address of the VSPC module to be provided to a client by transmission of an email message via a mail server to thereby enable the client to remotely access the one or more serial port interfaces . a determination module for determining an Internet Protocol, IP, address of a Virtual Serial Port Concentrator, VSPC, module deployed with the one or more virtual machines within the cloud application and that is specific to the cloud application ; a coupling module for causing a serial port interface of each of the one or more virtual machines to be communicatively coupled with the VSPC module ; an acquisition module for acquiring, from the VSPC module , one or more port numbers of the VSPC module that are associated with the one or more virtual machines , wherein each of the one or more port numbers can be used to remotely access the serial port interface of the corresponding virtual machine through the VSPC module ; and a providing module for causing the one or more port numbers and the IP address of the VSPC module to be provided to a client by transmission of an email message via a mail server to thereby enable the client to remotely access the one or more serial port interfaces .
A tissue collection device for collection of one or more tissue samples from a biopsy needle , the tissue collection device including a tissue sample positioning arrangement adapted to support a biopsy needle holding a tissue sample relative to a housing of the tissue collection device in a fixed position in a transverse direction of the biopsy needle , wherein the tissue collection device includes a sample storage with at least one sample compartment having the form of a channel, wherein the sample storage is configured as a drum , in which the sample compartments are arranged along the periphery of the drum, wherein the drum is arranged to be rotated a number of angular steps corresponding to the distance between two neighbouring sample compartments , and wherein the tissue collection device is adapted to perform a tissue collection operation by displacement of the drum relative to the housing in the direction of the biopsy needle and back again when the drum has been rotated one or more angular steps, wherein the tissue collection device includes a carrier medium , and the tissue collection device is adapted to perform the tissue collection operation by movement of the carrier medium in a transverse direction of the biopsy needle by relative movement between the carrier medium and the biopsy needle by firstly bringing the carrier medium into physical contact with a tissue sample held by a sample part of the biopsy needle , and by secondly bringing the carrier medium away from the sample part of the biopsy needle characterized in that the carrier medium is adapted to adhere to a tissue sample and in that the carrier medium is arranged in the channel forming the at least one sample compartment .
A method for controlling a paced breathing device , comprising: determining a flow rate for pumping air into an airbag of the paced breathing device in an exhalation phase of the paced breathing device ; and pumping , at the determined flow rate, the air into the airbag in the exhalation phase during which the airbag releases the air in order to control the exhalation time length of the exhalation phase. determining a flow rate for pumping air into an airbag of the paced breathing device in an exhalation phase of the paced breathing device ; and pumping , at the determined flow rate, the air into the airbag in the exhalation phase during which the airbag releases the air in order to control the exhalation time length of the exhalation phase.
A method performed by an appliance for washing and rinsing goods of detecting process water added to a sump of the appliance during interruption of operation of the appliance , upon recommence of appliance operation, the method comprising: increasing (S101) operating speed of a circulation pump of the appliance to a target speed; measuring (S102) a parameter indicating circulation pump pressure or process water flow rate through the circulation pump ; determining (S103) that process water has been added to the sump of the appliance during the interruption in case the measured pressure or flow rate is maintained at a sufficient level after the speed of the circulation pump has reached the target speed. increasing (S101) operating speed of a circulation pump of the appliance to a target speed; measuring (S102) a parameter indicating circulation pump pressure or process water flow rate through the circulation pump ; determining (S103) that process water has been added to the sump of the appliance during the interruption in case the measured pressure or flow rate is maintained at a sufficient level after the speed of the circulation pump has reached the target speed.
A spring steel having a superior fatigue life, wherein its chemical composition based on weight percentage is: C: 0.52-0.62%; Si: 1.20-1.45%; Mn: 0.25-0.75%; Cr: 0.30-0.80%; V: 0.01-0.15%; Nb: 0.001-0.05%; N: 0.001-0.009%; O: 0.0005-0.0040%; P: <_0.015%; S: <_0.015%; Al: <_0.0045%; a balance of Fe and unavoidable impurities, wherein the following relationship is satisfied: 0.02≤(2Nb+V)/(20N+C)≤0.40; the spring steel has a tensile strength ≥ 2020 MPa, an area reduction rate ≥ 40 %, and a fatigue life ≥ 800000 cycles according to GBT16947-2009 "Helical Spring Fatigue Testing Standard"; the spring steel has a microstructure that is a tempered troostite + sorbite structure, an original austenite grain size ≤ 80 μm, a size of alloying nitride and carbide precipitates in the range of 5-60 nm, and a maximum width of monoparticle inclusions ≤ 30 μm C: 0.52-0.62%; Si: 1.20-1.45%; Mn: 0.25-0.75%; Cr: 0.30-0.80%; V: 0.01-0.15%; Nb: 0.001-0.05%; N: 0.001-0.009%; O: 0.0005-0.0040%; P: <_0.015%; S: <_0.015%; Al: <_0.0045%; a balance of Fe and unavoidable impurities, wherein the following relationship is satisfied: 0.02≤(2Nb+V)/(20N+C)≤0.40; the spring steel has a tensile strength ≥ 2020 MPa, an area reduction rate ≥ 40 %, and a fatigue life ≥ 800000 cycles according to GBT16947-2009 "Helical Spring Fatigue Testing Standard"; the spring steel has a microstructure that is a tempered troostite + sorbite structure, an original austenite grain size ≤ 80 μm, a size of alloying nitride and carbide precipitates in the range of 5-60 nm, and a maximum width of monoparticle inclusions ≤ 30 μm
Method for controlling the stability conditions of a machine moveable on a ground (G) having at least an operational component , in particular a hydraulic cylinder, for moving a portion of the machine , and being maneuvered by an operator through operational commands, the method comprising: acquiring (S101) at least a first sensor signal defining the position of the portion of the machine ; acquiring (S102) at least a second sensor signal defining a variation of the position of the portion of the machine relative to the ground (G); acquiring (S103) at least a command signal defining the operational commands of the operator for actuating the operational component and for transmitting an operational velocity to said portion of the machine ; determining (S104) a stability condition of the machine based on the first sensor signal , the second sensor signal and the command signal , and outputting (S105) a control signal to control the operational component as a function of the determined stability condition, wherein the stability condition is determined by monitoring and estimating both the static and the dynamic stability conditions of the machine , by monitoring and estimating the position of the center of gravity and of an index of stability of the machine , relative to a contact area of the machine with the ground (G), characterized in that estimating the dynamic stability comprises an acceleration scaling process, the method comprising generating a corrected operational acceleration based on said acceleration scaling process. acquiring (S101) at least a first sensor signal defining the position of the portion of the machine ; acquiring (S102) at least a second sensor signal defining a variation of the position of the portion of the machine relative to the ground (G); acquiring (S103) at least a command signal defining the operational commands of the operator for actuating the operational component and for transmitting an operational velocity to said portion of the machine ; determining (S104) a stability condition of the machine based on the first sensor signal , the second sensor signal and the command signal , and outputting (S105) a control signal to control the operational component as a function of the determined stability condition, wherein the stability condition is determined by monitoring and estimating both the static and the dynamic stability conditions of the machine , by monitoring and estimating the position of the center of gravity and of an index of stability of the machine , relative to a contact area of the machine with the ground (G), characterized in that estimating the dynamic stability comprises an acceleration scaling process, the method comprising generating a corrected operational acceleration based on said acceleration scaling process.
A method of wireless communications by a wireless communications device , comprising: receiving information indicating whether a hybrid automatic repeat request, HARQ, re-transmission is permitted to use a first uplink waveform that is different from a second uplink waveform of a prior corresponding HARQ transmission or a prior corresponding HARQ re-transmission; and sending the HARQ re-transmission using either the first uplink waveform or the second uplink waveform based at least in part on the information indicating whether the HARQ re-transmission is permitted to use the first uplink waveform, wherein either the first uplink waveform is a DFT-s-OFDM-based waveform and the second uplink waveform is a CP-OFDM-based waveform or the first uplink waveform is a CP-OFDM-based waveform and the second uplink waveform is a DFT-s-OFDM-based waveform. receiving information indicating whether a hybrid automatic repeat request, HARQ, re-transmission is permitted to use a first uplink waveform that is different from a second uplink waveform of a prior corresponding HARQ transmission or a prior corresponding HARQ re-transmission; and sending the HARQ re-transmission using either the first uplink waveform or the second uplink waveform based at least in part on the information indicating whether the HARQ re-transmission is permitted to use the first uplink waveform, wherein either the first uplink waveform is a DFT-s-OFDM-based waveform and the second uplink waveform is a CP-OFDM-based waveform or the first uplink waveform is a CP-OFDM-based waveform and the second uplink waveform is a DFT-s-OFDM-based waveform.