mhurhangee/patent-ind-claim-en huggingface dataset:
A method for monitoring and detection of early relapse or metastasis of a tumor in a cancer patient, wherein the method comprises the steps of: a) selecting one or more patient-specific mutations based on somatic mutations identified in a tumor sample of a patient who has been diagnosed with a cancer; b) longitudinally collecting one or more blood samples from the patient after the patient has been treated with surgery, first-line chemotherapy, and/or adjuvant therapy; c) generating a set of amplicons from cellular DNA isolated from one or more circulating cells that are suspected to be circulating tumor cells and are obtained from a blood sample of the patient, wherein the set of amplicons are generated by multiplex amplification of genomic loci encompassing the patient-specific mutations associated with cancer; d) sequencing the set of amplicons by next-generation sequencing and determining the origin of the one or more circulating cells based on the presence of one or more patient-specific mutations in the set of amplicons, wherein the detection of one or more circulating tumor cells comprising the one or more patient-specific mutations is indicative of early relapse or metastasis of the cancer. a) selecting one or more patient-specific mutations based on somatic mutations identified in a tumor sample of a patient who has been diagnosed with a cancer; b) longitudinally collecting one or more blood samples from the patient after the patient has been treated with surgery, first-line chemotherapy, and/or adjuvant therapy; c) generating a set of amplicons from cellular DNA isolated from one or more circulating cells that are suspected to be circulating tumor cells and are obtained from a blood sample of the patient, wherein the set of amplicons are generated by multiplex amplification of genomic loci encompassing the patient-specific mutations associated with cancer; d) sequencing the set of amplicons by next-generation sequencing and determining the origin of the one or more circulating cells based on the presence of one or more patient-specific mutations in the set of amplicons, wherein the detection of one or more circulating tumor cells comprising the one or more patient-specific mutations is indicative of early relapse or metastasis of the cancer.
A modular dental system comprising: a control module including a first end, a second end, a control sub-system configured to communicatively couple to an attachment , detect an attachment identifier associated with the attachment when the attachment is removably attached to the first end of the control module, and control the attachment based on the attachment identifier, and a charging sub-system; and a battery module configured to removably attach to the second end of the control module; and a driver module configured to removably attach to the first end of the control module and removably attach to a first attachment . a control module including a first end, a second end, a control sub-system configured to communicatively couple to an attachment , detect an attachment identifier associated with the attachment when the attachment is removably attached to the first end of the control module, and control the attachment based on the attachment identifier, and a charging sub-system; and a first end, a second end, a control sub-system configured to communicatively couple to an attachment , detect an attachment identifier associated with the attachment when the attachment is removably attached to the first end of the control module, and control the attachment based on the attachment identifier, and a charging sub-system; and a battery module configured to removably attach to the second end of the control module; and a driver module configured to removably attach to the first end of the control module and removably attach to a first attachment .
An assembly for controlling a travel direction of a self-balancing double-wheeled electrical scooter, wherein the travel direction of the self-balancing double-wheeled electrical scooter is controlled via a handle on a scooter body , the assembly comprising the handle, the scooter body and a resilient recoverable component that is provided between the scooter body and the handle, the handle is adapted for driving the resilient recoverable component to control the travel direction of the scooter, the resilient recoverable component comprises a stator , a rotor and a resilient recoverable unit , the rotor is mechanically connected to the handle in a fixed manner directly or indirectly, the stator is mechanically connected to the scooter body in a fixed manner directly or indirectly, the stator and the rotor are connected in a resilient manner via the resilient recoverable unit, the resilient recoverable component between the scooter body and the handle further comprises an angle limiting device which limits rotation of the rotor to a certain angle range, the angle limiting device comprises a limiting cover and a limiting pin , the limiting cover is mechanically connected to the stator in a fixed manner directly or indirectly, a limiting hole is provided on the limiting cover , the limiting pin is mechanically connected to the rotor in a fixed manner directly or indirectly, and the rotation of the rotor causes the limiting pin to rotate within a certain angle range inside the limiting hole on the limiting cover , characterized in that a position limiting component is provided between the stator and the rotor for preventing all movements of the rotor relative to the stator other than rotation, and the resilient recoverable unit is a rubber unit or a silicone unit injection molded between the stator and the rotor , the contact surfaces between the stator and the resilient recoverable unit and between the rotor and the resilient recoverable unit are formed as a rough surface or a dented patterned surface. characterized in that a position limiting component is provided between the stator and the rotor for preventing all movements of the rotor relative to the stator other than rotation, and the resilient recoverable unit is a rubber unit or a silicone unit injection molded between the stator and the rotor , the contact surfaces between the stator and the resilient recoverable unit and between the rotor and the resilient recoverable unit are formed as a rough surface or a dented patterned surface.
A method for manufacturing an interconnect structure, the method comprising: providing a substrate structure including a substrate and a first dielectric layer on the substrate , the first dielectric layer having an opening for a first interconnect layer extending to the substrate ; forming a first mask layer on a portion of the first dielectric layer spaced apart from the opening ; forming a first metal layer filling the opening and covering a portion of the first dielectric layer not covered by the first mask layer , the first metal layer having a first portion in the opening and a second portion in contact with the first portion and on a portion of the first dielectric layer adjacent to the opening ; removing the first mask layer exposing a portion of the first dielectric layer ; forming a second dielectric layer on the exposed portion of the first dielectric layer and on the first metal layer , removing a portion of the second dielectric layer to form a trench for a second interconnect layer; and forming a second metal layer filling the trench to form an upper portion of the second interconnect layer, wherein forming the trench comprises exposing the second portion of the first metal layer , wherein the first portion of the first metal layer forms the first interconnect layer and the second portion of the first metal layer forms a lower portion of the second interconnect layer that is in contact with the upper portion of the second interconnect layer. providing a substrate structure including a substrate and a first dielectric layer on the substrate , the first dielectric layer having an opening for a first interconnect layer extending to the substrate ; forming a first mask layer on a portion of the first dielectric layer spaced apart from the opening ; forming a first metal layer filling the opening and covering a portion of the first dielectric layer not covered by the first mask layer , the first metal layer having a first portion in the opening and a second portion in contact with the first portion and on a portion of the first dielectric layer adjacent to the opening ; removing the first mask layer exposing a portion of the first dielectric layer ; forming a second dielectric layer on the exposed portion of the first dielectric layer and on the first metal layer , removing a portion of the second dielectric layer to form a trench for a second interconnect layer; and forming a second metal layer filling the trench to form an upper portion of the second interconnect layer, wherein forming the trench comprises exposing the second portion of the first metal layer , wherein the first portion of the first metal layer forms the first interconnect layer and the second portion of the first metal layer forms a lower portion of the second interconnect layer that is in contact with the upper portion of the second interconnect layer.
A method for manufacturing a blade outer airseal comprising a body comprising: an inner diameter (ID) surface ; an outer diameter (OD) surface; a leading end; a trailing end; a metallic substrate ; and a coating system along the substrate along at least a portion of the inner diameter surface , wherein at least over a first area of the inner diameter surface , the coating system comprises an abradable layer , the method comprising thermal spray of a metallic matrix and a filler to produce the abradable layer, wherein the filler comprises oxide particles, and the filler is sprayed from a source having agglomerates or aggregates of said oxide particles, said particles having a D50 size of 10nm to 50nm, wherein a D50 size of the agglomerates or aggregates is 6 to 45 micrometers, and the metallic matrix is sprayed from a source having particles of the matrix with a D50 size of 22-90 micrometers, wherein the agglomerates or aggregates of said oxide particles form at least 20% by volume of the abradable layer . an inner diameter (ID) surface ; an outer diameter (OD) surface; a leading end; a trailing end; a metallic substrate ; and a coating system along the substrate along at least a portion of the inner diameter surface , wherein at least over a first area of the inner diameter surface , the coating system comprises an abradable layer , the method comprising thermal spray of a metallic matrix and a filler to produce the abradable layer, wherein the filler comprises oxide particles, and the filler is sprayed from a source having agglomerates or aggregates of said oxide particles, said particles having a D50 size of 10nm to 50nm, wherein a D50 size of the agglomerates or aggregates is 6 to 45 micrometers, and the metallic matrix is sprayed from a source having particles of the matrix with a D50 size of 22-90 micrometers, wherein the agglomerates or aggregates of said oxide particles form at least 20% by volume of the abradable layer .
A measuring assembly for measuring a temperature and a voltage, comprising: - a contact element comprising a temperature sensing means and an electrically conductive portion ; - a voltage measurement conductor which is electrically connected to the conductive portion of the contact element ; characterized in that , the assembly further comprises an electrically conductive fixation element being a fixation clip, which is electrically connected to the conductive portion of the contact element , wherein the fixation element is adapted such that it extends through a fixation hole of a busbar in a fixed state and connects to the busbar by an elastic force provided by the fixation element in the fixed state; and wherein the fixation element being the fixation clip is adapted such that, in the fixed state, it presses the contact element to a measuring surface of the busbar by an elastic force provided by the fixation element in the fixed state. - a contact element comprising a temperature sensing means and an electrically conductive portion ; - a voltage measurement conductor which is electrically connected to the conductive portion of the contact element ; the assembly further comprises an electrically conductive fixation element being a fixation clip, which is electrically connected to the conductive portion of the contact element , wherein the fixation element is adapted such that it extends through a fixation hole of a busbar in a fixed state and connects to the busbar by an elastic force provided by the fixation element in the fixed state; and wherein the fixation element being the fixation clip is adapted such that, in the fixed state, it presses the contact element to a measuring surface of the busbar by an elastic force provided by the fixation element in the fixed state.
A liquid cyclopentene ring-opened polymer in the liquid state at 25°C having a weight average molecular weight (Mw) of 1,000 to 9,000 and a cis double bond content of 55% or more in repeating units, wherein the weight average molecular weight (Mw) is measured by gel permeation chromatography and is calibrated with polystyrene standards, and the cis double bond content is determined by 13 C-NMR spectrometry. the weight average molecular weight (Mw) is measured by gel permeation chromatography and is calibrated with polystyrene standards, and the cis double bond content is determined by 13 C-NMR spectrometry.
A decoding device comprising at least one circuit configured to: acquire a plurality of encoded audio signals for a plurality of objects, priority information for each of the plurality of objects and high frequency power values for the plurality of objects; select an encoded audio signal according to the priority information; decode the selected encoded audio signal; perform an inverse modified discrete cosine transform and overlappingly add the decoded audio signal; perform a gain adjustment of the decoded audio signal overlappingly added based on the priority information of the object at the time and the priority information of the object at the other time before or after the time; generate a high frequency component of the decoded signal overlappingly added based on the high frequency power value; synthesize the high frequency component and the decoded audio signal overlappingly added. acquire a plurality of encoded audio signals for a plurality of objects, priority information for each of the plurality of objects and high frequency power values for the plurality of objects; select an encoded audio signal according to the priority information; decode the selected encoded audio signal; perform an inverse modified discrete cosine transform and overlappingly add the decoded audio signal; perform a gain adjustment of the decoded audio signal overlappingly added based on the priority information of the object at the time and the priority information of the object at the other time before or after the time; generate a high frequency component of the decoded signal overlappingly added based on the high frequency power value; synthesize the high frequency component and the decoded audio signal overlappingly added.
A disposable diaper having a transverse and longitudinal dimension comprising a backsheet , a topsheet and an absorbent core disposed therebetween, wherein said absorbent core comprises at least one absorbent structure comprising a first substrate layer and an absorbent layer comprising absorbent polymer particles and cellulose, supported by, and immobilized on said substrate layer , said absorbent layer having: i. a transverse (N) and longitudinal dimension (M); and ii. a pair of opposing longitudinal edges extending in said longitudinal dimension; and iii. a pair of opposing transversal edges extending in said transverse dimension; and iv. a front, crotch and back regions arranged sequentially in said longitudinal dimension; and v. two longitudinal portions delimited by a central longitudinal axis of said absorbent layer ; wherein said absorbent layer comprises at least two channels substantially free of said absorbent polymeric particles extending through the thickness of said absorbent layer in its longitudinal dimension, wherein each longitudinal portion of said absorbent layer comprises one of said channels and wherein each of said channels : a. has a width of at least 3 mm or of at least 4% of the transverse dimension of said absorbent layer ; and b. extends over at least 15% of the longitudinal dimension of said absorbent layer ; and c. is at least present in said crotch region or part thereof; wherein said absorbent layer does not comprise channels substantially free of absorbent polymer particles extending in its transverse dimension in said crotch region , and wherein said absorbent layer does not comprise channels substantially free of absorbent polymeric particles extending up to its longitudinal and transverse edges ; and wherein the channels are formed by bonding of the first substrate layer to a second substrate layer through the channels so that the channels are at least partially maintained both in the dry state and in the wet state. i. a transverse (N) and longitudinal dimension (M); and ii. a pair of opposing longitudinal edges extending in said longitudinal dimension; and iii. a pair of opposing transversal edges extending in said transverse dimension; and iv. a front, crotch and back regions arranged sequentially in said longitudinal dimension; and v. two longitudinal portions delimited by a central longitudinal axis of said absorbent layer ; a. has a width of at least 3 mm or of at least 4% of the transverse dimension of said absorbent layer ; and b. extends over at least 15% of the longitudinal dimension of said absorbent layer ; and c. is at least present in said crotch region or part thereof;
An apparatus comprising a processor configured to: determine a number of future use cycles of an aircraft wheel brake based on a predicted condition of the brake , wherein the number of further use cycles is the number of use cycles for which the brake is allowed to be used, and a use cycle comprises all uses of the brake relating to a flight undertaken by the aircraft, and wherein the predicted condition comprises a predicted wear state of the brake , and the processor is configured to: determine a wear relationship between a wear state of the brake and a number of use cycles of the brake ; and determine the predicted wear state based on the wear relationship. determine a number of future use cycles of an aircraft wheel brake based on a predicted condition of the brake , wherein the number of further use cycles is the number of use cycles for which the brake is allowed to be used, and a use cycle comprises all uses of the brake relating to a flight undertaken by the aircraft, and wherein the predicted condition comprises a predicted wear state of the brake , and the processor is configured to: determine a wear relationship between a wear state of the brake and a number of use cycles of the brake ; and determine the predicted wear state based on the wear relationship.
A tire comprising: a projection disposed between a tread end (TE) and a maximum width position (PW) on a side surface of the tire , wherein the projection includes a single groove that extends through an outer side surface of the projection in a circumferential direction (A), and the groove is disposed in a region in which a distance from an outer side end of the tire is 15% to 45% of a cross-sectional height (H1) of the tire in a radial direction (X), characterized in that a width (GW) of the groove is not less than 1.5 mm and not greater than 3.0 mm, and a depth (GD) of the groove is not less than 15% of a thickness (T) of the projection and not greater than 30% of the thickness (T) of the projection . a projection disposed between a tread end (TE) and a maximum width position (PW) on a side surface of the tire , wherein the projection includes a single groove that extends through an outer side surface of the projection in a circumferential direction (A), and the groove is disposed in a region in which a distance from an outer side end of the tire is 15% to 45% of a cross-sectional height (H1) of the tire in a radial direction (X), characterized in that a width (GW) of the groove is not less than 1.5 mm and not greater than 3.0 mm, and a depth (GD) of the groove is not less than 15% of a thickness (T) of the projection and not greater than 30% of the thickness (T) of the projection .
An installation comprising a device and at least one piece of audio playback equipment , the device being configured to determine whether an audio stream is played back in the installation by only one piece of audio playback equipment or by a group of at least two pieces of audio playback equipment , the device being distinct from said pieces of audio playback equipment, the device also being configured: . if the device detects that the audio stream is played back by a single piece of audio playback equipment, to generate an order for said piece of equipment to apply a given set of equalization parameters; · if the device detects that the audio stream is played back by a group of at least two pieces of audio playback equipment, to determine the equalization parameters to be applied by each piece of audio playback equipment of said group, and to generate a respective order for each piece of audio playback equipment of said group to apply a respective given set of equalization parameters, the pieces of audio playback equipment applying the equalization parameters without intervention from an user and also without said pieces of audio playback equipment needing to determine whether they form part of a group or whether they are playing back the audio stream on their own. . if the device detects that the audio stream is played back by a single piece of audio playback equipment, to generate an order for said piece of equipment to apply a given set of equalization parameters; · if the device detects that the audio stream is played back by a group of at least two pieces of audio playback equipment, to determine the equalization parameters to be applied by each piece of audio playback equipment of said group, and to generate a respective order for each piece of audio playback equipment of said group to apply a respective given set of equalization parameters, · if the device detects that the audio stream is played back by a group of at least two pieces of audio playback equipment, to determine the equalization parameters to be applied by each piece of audio playback equipment of said group, and to generate a respective order for each piece of audio playback equipment of said group to apply a respective given set of equalization parameters,
A surface cleaning head comprising: a main body ; a neck pivotally coupled to the main body ; a stabilizer ; and a linkage pivotally coupled to the main body and the stabilizer , wherein the linkage is configured to cause the stabilizer to transition between an extended position and a retracted position in response to a pivotal movement of the neck between a storage position and an in-use position, characterized in that the linkage includes a pivot arm and a plunger , the pivot arm defining a channel for receiving the plunger . a main body ; a neck pivotally coupled to the main body ; a stabilizer ; and a linkage pivotally coupled to the main body and the stabilizer , wherein the linkage is configured to cause the stabilizer to transition between an extended position and a retracted position in response to a pivotal movement of the neck between a storage position and an in-use position, characterized in that the linkage includes a pivot arm and a plunger , the pivot arm defining a channel for receiving the plunger .