mhurhangee/patent-ind-claim-en huggingface dataset:
An apparatus comprising: a thick waveguide comprising a first adiabatic tapering from a first location to a second location , wherein the first adiabatic tapering is wider at the first location than at the second location ; a thin slab waveguide comprising: a second adiabatic tapering from the first location to the second location , wherein the second adiabatic tapering is wider at the second location than at the first location ; and a third adiabatic tapering from the second location to a third location , wherein the third adiabatic tapering is wider at the second location than at the third location , and a low-index waveguide coupled to the thin slab waveguide at the third adiabatic tapering and optionally a cladding coupled to the thin slab waveguide at the third adiabatic tapering and disposed between the thin slab waveguide and the low-index waveguide ; wherein the height of the thin slab waveguide is about 10% to 90% of the height of the thick waveguide , and the thin slab waveguide is coupled to an optical fiber at the third location , wherein at least a portion of the first adiabatic tapering is adjacent to the second adiabatic tapering, wherein the first adiabatic tapering and the second adiabatic tapering are separated from each other by a constant gap . a thick waveguide comprising a first adiabatic tapering from a first location to a second location , wherein the first adiabatic tapering is wider at the first location than at the second location ; a thin slab waveguide comprising: a second adiabatic tapering from the first location to the second location , wherein the second adiabatic tapering is wider at the second location than at the first location ; and a third adiabatic tapering from the second location to a third location , wherein the third adiabatic tapering is wider at the second location than at the third location , and a second adiabatic tapering from the first location to the second location , wherein the second adiabatic tapering is wider at the second location than at the first location ; and a third adiabatic tapering from the second location to a third location , wherein the third adiabatic tapering is wider at the second location than at the third location , and a low-index waveguide coupled to the thin slab waveguide at the third adiabatic tapering and optionally a cladding coupled to the thin slab waveguide at the third adiabatic tapering and disposed between the thin slab waveguide and the low-index waveguide ; wherein the height of the thin slab waveguide is about 10% to 90% of the height of the thick waveguide , and the thin slab waveguide is coupled to an optical fiber at the third location , wherein at least a portion of the first adiabatic tapering is adjacent to the second adiabatic tapering, wherein the first adiabatic tapering and the second adiabatic tapering are separated from each other by a constant gap .
An adeno-associated virus (AAV) vector comprising a VP1 capsid protein comprising one or more lysine substitutions selected from K61R, K84R, K137R, K143R, K161R, K459R, K533R, and K707R of AAV1 VP1 capsid protein, said vector further comprising a minigene comprising AAV inverted terminal repeats and a heterologous nucleic acid sequence operably linked to regulatory sequences which direct expression of a product from the heterologous nucleic acid sequence in a host cell, said lysine substitution being effective to inhibit ubiquitination of said capsid protein, thereby increasing transduction of said AAV vector into a target cell, compared to an AAV vector comprising the AAV1 VP1 capsid protein without the one or more lysine substitutions.
An immobilized nuclear containing waste, wherein a composition is used to immobilize nuclear containing waste containing at least one radioactive element or alloy of uranium, graphite, magnesium, and aluminum, said composition comprising: at least one mineral phase forming element or compound that reacts with said at least one radioactive element or alloy; and at least one glass-forming element or compound to form a glass phase that incorporates waste radioisotopes and impurities that do not react with said least one mineral phase forming element or compound, wherein the composition immobilizes said nuclear containing waste in a solid wasteform; wherein said nuclear containing waste comprises a magnesium metal, carbonate or hydroxide, and the mineral phase is sufficient to convert the magnesium metal, carbonate or hydroxide to MgO, or wherein said nuclear containing waste comprises a uranium metal and/or hydrated and carbonated uranium, and the mineral phase is sufficient to convert the uranium oxide, or wherein nuclear containing waste comprises magnox sludges, clinoptilolite wastes, and combinations thereof. at least one mineral phase forming element or compound that reacts with said at least one radioactive element or alloy; and at least one glass-forming element or compound to form a glass phase that incorporates waste radioisotopes and impurities that do not react with said least one mineral phase forming element or compound, wherein the composition immobilizes said nuclear containing waste in a solid wasteform; wherein said nuclear containing waste comprises a magnesium metal, carbonate or hydroxide, and the mineral phase is sufficient to convert the magnesium metal, carbonate or hydroxide to MgO, or wherein said nuclear containing waste comprises a uranium metal and/or hydrated and carbonated uranium, and the mineral phase is sufficient to convert the uranium oxide, or wherein nuclear containing waste comprises magnox sludges, clinoptilolite wastes, and combinations thereof.
Beverage preparation machine, comprising a tank , a feed pump , a heat exchanger , and provided with an infusion unit (1; 5) comprising an infusion chamber (101, 201; 105, 205), equipped with means for feeding the infusion liquid (251; 255) and dispensing means for the prepared drink (121; 125), formed by two complementary portions and suitable, once coupled, for receiving a prepackaged charge of edible material, in which the two portions of said infusion chamber are provided with movement relative to each other, and the movement is suitably guided, and means for coupling between the two portions are provided, releasable ; said two portions of said infusion chamber are one movable (201; 205) and one fixed (101; 105), being said movable portion (201; 205) equipped with actuation means comprising a hydraulic jack (501; 505) mechanically coupled to said movable portion (201; 205), and inserted in the circuit for feeding pressurized water to the infusion chamber, and releasable locking means being provided (481, 431, 491, 471; 435, 605, 625) of the coupling between said two portions of the infusion chamber, in which said jack (501; 505) is inserted in the pressurized water supply circuit downstream of the pump , upstream of the heat exchanger and in series with it, characterized in that the said jack (501; 505) is able to act as a distribution valve for the pressurized liquid fed by the pump, being provided with a duct (531; 515) which opens radially from the cylinder (501; 505) of said jack, and communicates with the heat exchanger of the machine.
A flange connection for a building services appliance comprising a storage tank with an opening to be closed, with - a connecting flange which can be connected to the storage tank , - a fixing flange which can be reversibly coupled to the connecting flange , and - a closing body arranged between the connecting flange and the fixing flange , wherein a sealing element for a sealing connection to at least the connecting flange is assigned to the closing body , wherein a spacer is assigned to the closing body , characterised in that the spacer is arranged for galvanic decoupling of the closing body from the connecting flange or the fixing flange , and in that the closing body has a first clamping surface as a receptacle for the sealing element and a second clamping surface as a contact surface for the spacer , wherein preferably the first clamping surface faces the connecting flange and the second clamping surface faces the fixing flange . - a connecting flange which can be connected to the storage tank , - a fixing flange which can be reversibly coupled to the connecting flange , and - a closing body arranged between the connecting flange and the fixing flange , wherein a sealing element for a sealing connection to at least the connecting flange is assigned to the closing body , wherein a spacer is assigned to the closing body , characterised in that the spacer is arranged for galvanic decoupling of the closing body from the connecting flange or the fixing flange , and in that the closing body has a first clamping surface as a receptacle for the sealing element and a second clamping surface as a contact surface for the spacer , wherein preferably the first clamping surface faces the connecting flange and the second clamping surface faces the fixing flange .
A passive multiphase separator configured to separate gas from a two-phase fluid in a wellbore, the passive multiphase separator comprising: an intake tube , wherein the intake tube comprises: an intake end ; a discharge end ; and an interior section between the intake end and the discharge end , wherein the interior section includes a rifled interior surface; and a head assembly connected to the discharge end of the intake tube , wherein the head assembly comprises: a crossover tube extending into the interior section ; one or more gas vents extending from an interior of the crossover tube to an exterior of the head assembly ; and a liquid discharge . an intake tube , wherein the intake tube comprises: an intake end ; a discharge end ; and an interior section between the intake end and the discharge end , wherein the interior section includes a rifled interior surface; and an intake end ; a discharge end ; and an interior section between the intake end and the discharge end , wherein the interior section includes a rifled interior surface; and a head assembly connected to the discharge end of the intake tube , wherein the head assembly comprises: a crossover tube extending into the interior section ; one or more gas vents extending from an interior of the crossover tube to an exterior of the head assembly ; and a liquid discharge . a crossover tube extending into the interior section ; one or more gas vents extending from an interior of the crossover tube to an exterior of the head assembly ; and a liquid discharge .
A refrigerator comprising: a main body ; a storage compartment formed in the main body and having an open front side; a door provided to open and close the storage compartment ; an evaporator provided to generate cold air; a rear duct including a first guide passage configured to guide the cold air generated in the evaporator and a cooling discharge port through which the cold air is discharged from the first guide passage to an inside of the storage compartment to cool the storage compartment ; an upper duct including a second guide passage coupled with the first guide passage and an air curtain discharge port through which the cold air is discharged from the second guide passage to a front opening of the storage compartment to form an air curtain at the front opening of the storage compartment ; and a blade provided to close or open the air curtain discharge port ; characterized in that a cross-sectional area (S2) of an outlet of the first guide passage is greater than a cross-sectional area (S1) of an inlet of the first guide passage . a main body ; a storage compartment formed in the main body and having an open front side; a door provided to open and close the storage compartment ; an evaporator provided to generate cold air; a rear duct including a first guide passage configured to guide the cold air generated in the evaporator and a cooling discharge port through which the cold air is discharged from the first guide passage to an inside of the storage compartment to cool the storage compartment ; an upper duct including a second guide passage coupled with the first guide passage and an air curtain discharge port through which the cold air is discharged from the second guide passage to a front opening of the storage compartment to form an air curtain at the front opening of the storage compartment ; and a blade provided to close or open the air curtain discharge port ; characterized in that a cross-sectional area (S2) of an outlet of the first guide passage is greater than a cross-sectional area (S1) of an inlet of the first guide passage .
Procedure designed to determine a flow rate or a flow velocity of a medium , which at least interacts with a first and a second temperature sensor element (T 1 , T 2 ) and a heating element (H 1 ), wherein said procedure comprises the following steps: - Heating of the medium by means of the heating element (H 1 ) for a predefined heating period, wherein, prior to the heating, the medium is largely in thermal equilibrium with at least the first and the second temperature sensor element (T 1 , T 2 ); - Measurement of at least a first and a second measured value , wherein the second measured value is chronologically after the first measured value , with the aid of the first temperature sensor element (T 1 ) and at least a third and a fourth measured value , wherein the fourth measured value is chronologically after the third measured value , with the aid of the second temperature sensor element (T 2 ), for the purpose of characterizing a first and a second temperature increase of the medium ; - Determination of the flow rate or the flow velocity of the medium using the at least two temperature increases , characterized in that in order to characterize the two temperature increases , a first constant (a 1 ) and a first slope value (b 1 ) are determined for the first temperature increase , and a second constant (a 2 ) and a second slope value (b 2 ) are determined for the second temperature increase , wherein Ohmic resistance values (R 1 , R 2 ) for the temperature sensor element (T 1 , T 2 ) are determined in thermal equilibrium by means of the two constants (a 1 , a 2 ), and a temperature increase (ΔT 1 , ΔT 2 ) for the temperature sensor element (T 1 , T 2 ) is determined by means of the two slope values (b 1 , b 2 ), wherein the constants and the slope values are determined following a transformation of the time values for the linearization of the temperature increase. - Heating of the medium by means of the heating element (H 1 ) for a predefined heating period, wherein, prior to the heating, the medium is largely in thermal equilibrium with at least the first and the second temperature sensor element (T 1 , T 2 ); - Measurement of at least a first and a second measured value , wherein the second measured value is chronologically after the first measured value , with the aid of the first temperature sensor element (T 1 ) and at least a third and a fourth measured value , wherein the fourth measured value is chronologically after the third measured value , with the aid of the second temperature sensor element (T 2 ), for the purpose of characterizing a first and a second temperature increase of the medium ; - Determination of the flow rate or the flow velocity of the medium using the at least two temperature increases ,
An assay to determine anticoagulants in a blood or blood plasma sample, wherein the anticoagulants determined in said assay are direct acting inhibitors of activated coagulation factors Ila and Xa, which are selected from a group consisting of dabigatran, apixaban, rivaroxaban or hirudin or indirect acting inhibitors of activated coagulation factors IIa and Xa, selected from a group consisting of fractionated or unfractionated heparins, wherein said assay comprises analyses with at least two wet chemistry prothrombine time (PT) methods, the assay comprising the steps of: a) in a first PT analysis with a first PT method measure PT in a first reaction mixture comprising a first volume of blood or blood plasma diluted in a first volume of a liquid reagent comprising thromboplastin, fibrinogen and coagulation factor V; b) in a second PT analysis with a second PT method measure PT in a second reaction mixture comprising a second volume of said blood or blood plasma diluted in a second volume of said liquid reagent comprising thromboplastin, fibrinogen and coagulation factor V, wherein the concentration of blood or blood plasma in the second reaction mixture differs from the concentration of blood or blood plasma in the first reaction mixture; characterized in that said at least two PT methods are calibrated to: - give the same or approximately the same PT results when used to analyze reference blood or blood plasma which lack anticoagulants of interest for said assay; and wherein the assay further comprises the step of: c) calculating a difference in PT from the measurements in step a) and b), wherein if said difference in PT is 1) significant, this is indicative of a presence of anticoagulants in the blood or blood plasma sample; or 2) non-significant, this is indicative of an absence of anti-coagulants above detectable level in the blood or blood plasma sample. a) in a first PT analysis with a first PT method measure PT in a first reaction mixture comprising a first volume of blood or blood plasma diluted in a first volume of a liquid reagent comprising thromboplastin, fibrinogen and coagulation factor V; b) in a second PT analysis with a second PT method measure PT in a second reaction mixture comprising a second volume of said blood or blood plasma diluted in a second volume of said liquid reagent comprising thromboplastin, fibrinogen and coagulation factor V, wherein the concentration of blood or blood plasma in the second reaction mixture differs from the concentration of blood or blood plasma in the first reaction mixture; - give the same or approximately the same PT results when used to analyze reference blood or blood plasma which lack anticoagulants of interest for said assay; 1) significant, this is indicative of a presence of anticoagulants in the blood or blood plasma sample; or 2) non-significant, this is indicative of an absence of anti-coagulants above detectable level in the blood or blood plasma sample.
A method for producing hypromellose acetate succinate, comprising: an esterification step of esterifying hypromellose with an acetylating agent and a succinoylating agent in the presence of an aliphatic carboxylic acid to obtain a reaction product solution containing hypromellose acetate succinate; a precipitation step of precipitating the hypromellose acetate succinate by mixing the reaction product solution with water to obtain a suspension of the precipitated hypromellose acetate succinate; a neutralization step of neutralizing the suspension with a basic substance to obtain a neutralized suspension; and a washing step of washing the hypromellose acetate succinate contained in the neutralized suspension to obtain the washed hypromellose acetate succinate. an esterification step of esterifying hypromellose with an acetylating agent and a succinoylating agent in the presence of an aliphatic carboxylic acid to obtain a reaction product solution containing hypromellose acetate succinate; a precipitation step of precipitating the hypromellose acetate succinate by mixing the reaction product solution with water to obtain a suspension of the precipitated hypromellose acetate succinate; a neutralization step of neutralizing the suspension with a basic substance to obtain a neutralized suspension; and a washing step of washing the hypromellose acetate succinate contained in the neutralized suspension to obtain the washed hypromellose acetate succinate.
A package of a liquid battery material comprising: a liquid battery material ; a container that contains the liquid battery material ; and a wrapping cover enclosing an outer surface of the container , wherein the wrapping cover includes a bag-shaped sheet constituted by a sheet including a resin layer and having a shape of a bag with an opening, a surface resistance value of the sheet is 10 11 Ω/sq. or less, the bag-shaped sheet includes a contracting portion provided around the opening so as to be capable of adjusting a size of the opening, the wrapping cover further comprises a fastening member provided along the opening so as to be capable of adjusting the size of the opening, the enclosing is in a manner of covering an outer surface at at least an upper portion of the container with the opening of the wrapping cover facing downward, and the opening is closed at the contracting portion . a liquid battery material ; a container that contains the liquid battery material ; and a wrapping cover enclosing an outer surface of the container , wherein the wrapping cover includes a bag-shaped sheet constituted by a sheet including a resin layer and having a shape of a bag with an opening, a surface resistance value of the sheet is 10 11 Ω/sq. or less, the bag-shaped sheet includes a contracting portion provided around the opening so as to be capable of adjusting a size of the opening, the wrapping cover further comprises a fastening member provided along the opening so as to be capable of adjusting the size of the opening, the enclosing is in a manner of covering an outer surface at at least an upper portion of the container with the opening of the wrapping cover facing downward, and the opening is closed at the contracting portion .