A quality control (QC) method for a Huashibaidu (HSBD) composition, the HSBD composition mainly comprises the following components: ephedra, fried bitter almond, raw gypsum, licorice, PogostemonisHerba, Magnolia officinalis , bran-fried AtractylodesLancea, fried Amomum tsaoko fruit, RhizomaPinelliae, Poriacocos, Rheum palmatum, Astragalus membranaceus, Semen Lepidii, Paeoniae Radix Rubra, and an adjuvant; and characterized in that the QC method for an HSBD composition comprises: identifying ephedra, licorice, and Magnolia officinalis by thin-layer chromatography (TLC); and determining a total anthraquinone content, a free anthraquinone content, a total content of ephedrine hydrochloride and pseudoephedrine hydrochloride, and a paeoniflorin content in the HSBD composition by high-performance liquid chromatography (HPLC), and calculating a combined anthraquinone content, and the combined anthraquinone content = the total anthraquinone content - the free anthraquinone content; in determination of both the total anthraquinone content and the free anthraquinone content, the chromatography column is an octadecylsilane-bonded silica gel column, and the following elution program is adopted: mobile phase A is acetonitrile and mobile phase B is a phosphoric acid aqueous solution: 0 min to 10 min: mobile phase A: from 35% to 40%, and mobile phase B: from 65% to 60%; 10 min to 38 min: mobile phase A: from 40% to 60%, and mobile phase B: from 60% to 40%; and 38 min to 48 min: mobile phase A: 60%, and mobile phase B: 40%. characterized in that the QC method for an HSBD composition comprises: identifying ephedra, licorice, and Magnolia officinalis by thin-layer chromatography (TLC); and determining a total anthraquinone content, a free anthraquinone content, a total content of ephedrine hydrochloride and pseudoephedrine hydrochloride, and a paeoniflorin content in the HSBD composition by high-performance liquid chromatography (HPLC), and calculating a combined anthraquinone content, and the combined anthraquinone content = the total anthraquinone content - the free anthraquinone content; in determination of both the total anthraquinone content and the free anthraquinone content, the chromatography column is an octadecylsilane-bonded silica gel column, and the following elution program is adopted: mobile phase A is acetonitrile and mobile phase B is a phosphoric acid aqueous solution: 0 min to 10 min: mobile phase A: from 35% to 40%, and mobile phase B: from 65% to 60%; 10 min to 38 min: mobile phase A: from 40% to 60%, and mobile phase B: from 60% to 40%; and 38 min to 48 min: mobile phase A: 60%, and mobile phase B: 40%. identifying ephedra, licorice, and Magnolia officinalis by thin-layer chromatography (TLC); and determining a total anthraquinone content, a free anthraquinone content, a total content of ephedrine hydrochloride and pseudoephedrine hydrochloride, and a paeoniflorin content in the HSBD composition by high-performance liquid chromatography (HPLC), and calculating a combined anthraquinone content, and the combined anthraquinone content = the total anthraquinone content - the free anthraquinone content; in determination of both the total anthraquinone content and the free anthraquinone content, the chromatography column is an octadecylsilane-bonded silica gel column, and the following elution program is adopted: mobile phase A is acetonitrile and mobile phase B is a phosphoric acid aqueous solution: 0 min to 10 min: mobile phase A: from 35% to 40%, and mobile phase B: from 65% to 60%; 10 min to 38 min: mobile phase A: from 40% to 60%, and mobile phase B: from 60% to 40%; and 38 min to 48 min: mobile phase A: 60%, and mobile phase B: 40%. 0 min to 10 min: mobile phase A: from 35% to 40%, and mobile phase B: from 65% to 60%; 10 min to 38 min: mobile phase A: from 40% to 60%, and mobile phase B: from 60% to 40%; and 38 min to 48 min: mobile phase A: 60%, and mobile phase B: 40%. <EOS>