A screen calibration method comprising: acquiring a full screen image displayed on a screen Z comprising a plurality of regions by a camera to generate an acquired full screen image; acquiring first optical data of a first region (R1) of the screen by a sensor close to the screen and configured to acquire first optical data of the first region (R1) of the screen , wherein the first optical data acquired from the sensor is equivalent to a real luminous characteristic of the first region (R1) without introducing an ambient light signal; ; generating first calibration parameters according to target optical data and the first optical data; calibrating colors of the first region (R1) of the screen according to first calibration parameters to approach target optical data; the method being characterized by further comprising: determining a set of ambient light parameters for the first region (R1) according to the full screen image and the first optical data; estimating second optical data of a second region (R2) according to the acquired full screen image and the set of ambient light parameters for the first region (R1); generating second calibration parameters according to the target optical data and the second optical data; and calibrating colors of the second region (R2) of the screen according to the second calibration parameters to approach the target optical data. acquiring a full screen image displayed on a screen Z comprising a plurality of regions by a camera to generate an acquired full screen image; acquiring first optical data of a first region (R1) of the screen by a sensor close to the screen and configured to acquire first optical data of the first region (R1) of the screen , wherein the first optical data acquired from the sensor is equivalent to a real luminous characteristic of the first region (R1) without introducing an ambient light signal; ; generating first calibration parameters according to target optical data and the first optical data; calibrating colors of the first region (R1) of the screen according to first calibration parameters to approach target optical data; the method being characterized by further comprising: determining a set of ambient light parameters for the first region (R1) according to the full screen image and the first optical data; estimating second optical data of a second region (R2) according to the acquired full screen image and the set of ambient light parameters for the first region (R1); generating second calibration parameters according to the target optical data and the second optical data; and calibrating colors of the second region (R2) of the screen according to the second calibration parameters to approach the target optical data. determining a set of ambient light parameters for the first region (R1) according to the full screen image and the first optical data; estimating second optical data of a second region (R2) according to the acquired full screen image and the set of ambient light parameters for the first region (R1); generating second calibration parameters according to the target optical data and the second optical data; and calibrating colors of the second region (R2) of the screen according to the second calibration parameters to approach the target optical data. <EOS>