mhurhangee/patent-ind-claim-en huggingface dataset:
A method for selecting one or more antibodies with degradation stability comprising the following steps a) providing two or more antibodies, b) determining for each Asp and Asn residue in an antibody Fv region the conformational flexibility of the C α -atom using a homology model ensemble, c) determining for each Asp and Asn residue in an antibody Fv region the size of the amino acid residue C-terminal to the Asp or Asn residue, d) selecting one or more antibodies in which the C α -atom is conformationally inflexible and the Asp or Asn has a C-terminal amino acid residue with a solvent accessible surface area of 111 Å2 or more, wherein the conformational flexibility is the root mean square deviation (RMSD) of the respective Asn/Asp residues' C α -atoms in the homology model ensemble, and wherein i) conformational inflexible is a RMSD of 0.01 Å or less, ii) conformational flexible is a RMSD of more than 0.01 Å, iii) conformational moderate flexible is a RMSD between 0.145 Å and 0.485 Å, and iv) conformational highly flexible is a RMSD of more than 0.485 Å, and thereby selecting one or more antibodies with degradation stability. a) providing two or more antibodies, b) determining for each Asp and Asn residue in an antibody Fv region the conformational flexibility of the C α -atom using a homology model ensemble, c) determining for each Asp and Asn residue in an antibody Fv region the size of the amino acid residue C-terminal to the Asp or Asn residue, d) selecting one or more antibodies in which the C α -atom is conformationally inflexible and the Asp or Asn has a C-terminal amino acid residue with a solvent accessible surface area of 111 Å2 or more, i) conformational inflexible is a RMSD of 0.01 Å or less, ii) conformational flexible is a RMSD of more than 0.01 Å, iii) conformational moderate flexible is a RMSD between 0.145 Å and 0.485 Å, and iv) conformational highly flexible is a RMSD of more than 0.485 Å,
A cooling arrangement for cooling an electronic device in the passenger compartment of a motor vehicle , comprising an impeller based electric fan for cooling the electronic device , and an electronic fan controller adapted to use an algorithm to control said electric fan , wherein said electronic device is a camera for inspecting a vehicle environment, and wherein said fan controller has access to noise information correlating with the noise level in the surrounding of the electric fan and passenger presence information indicating the presence or absence of at least one passenger in the passenger compartment, wherein said noise information comprises information from a handsfree microphone of the motor vehicle and said passenger presence information comprises information from a seat occupancy sensor , wherein said fan controller is adapted to control said electric fan on the basis of said noise information and said passenger presence information, wherein the fan controller uses said noise information as an input to the algorithm, and whereby if no passenger presence is determined in the passenger compartment , or if the absence of the driver and/or co-driver is determined, the fan speed is controlled independently of the noise level in the passenger compartment , the cooling arrangement being characterised in that : the algorithm allows a noise level generated from the electric fan related to the noise level in the surrounding of the electric fan with a hysteresis.
A switching device , comprising: multiple Peripheral Component Interconnect Express, PCIe, upstream ports , configured to connect to at least one host ; at least one PCIe downstream port , configured to connect to at least one input/output, I/O, device ; and an internal processing apparatus , connected to the at least one PCIe downstream port by using an internal connection line of the switching device , characterized in that the internal processing apparatus is configured to: transmit a configuration read/write packet to the at least one PCIe downstream port by using the internal connection line; receive a configuration read/write response packet transmitted by the at least one PCIe downstream port by using the internal connection line, wherein the configuration read/write response packet carries a completer identification; and determine, according to the completer identification carried in the configuration read/write response packet, that the switching device is connected to an I/O device whose identification is the completer identification. multiple Peripheral Component Interconnect Express, PCIe, upstream ports , configured to connect to at least one host ; at least one PCIe downstream port , configured to connect to at least one input/output, I/O, device ; and an internal processing apparatus , connected to the at least one PCIe downstream port by using an internal connection line of the switching device , characterized in that the internal processing apparatus is configured to: transmit a configuration read/write packet to the at least one PCIe downstream port by using the internal connection line; receive a configuration read/write response packet transmitted by the at least one PCIe downstream port by using the internal connection line, wherein the configuration read/write response packet carries a completer identification; and determine, according to the completer identification carried in the configuration read/write response packet, that the switching device is connected to an I/O device whose identification is the completer identification. transmit a configuration read/write packet to the at least one PCIe downstream port by using the internal connection line; receive a configuration read/write response packet transmitted by the at least one PCIe downstream port by using the internal connection line, wherein the configuration read/write response packet carries a completer identification; and determine, according to the completer identification carried in the configuration read/write response packet, that the switching device is connected to an I/O device whose identification is the completer identification.
An object comprising a. a layer of carbon fiber reinforced plastic , b. an inner layer of ceramic material , c. a layer of aluminum and d. a outer layer of ceramic material , wherein the layer of aluminium is positioned between and is bound to the inner layer of ceramic material and the outer layer of ceramic material and wherein the inner layer of ceramic material is bound to the layer of carbon fiber reinforced plastic wherein the ceramic material is prepared by plasma electrolytic oxidation of aluminium, and wherein said ceramic material has a hardness according to Vickers (HV) of at least 750 measured according to DIN EN ISO 6507. a. a layer of carbon fiber reinforced plastic , b. an inner layer of ceramic material , c. a layer of aluminum and d. a outer layer of ceramic material , wherein the layer of aluminium is positioned between and is bound to the inner layer of ceramic material and the outer layer of ceramic material and wherein the inner layer of ceramic material is bound to the layer of carbon fiber reinforced plastic wherein the layer of aluminium is positioned between and is bound to the inner layer of ceramic material and the outer layer of ceramic material and wherein the inner layer of ceramic material is bound to the layer of carbon fiber reinforced plastic wherein the ceramic material is prepared by plasma electrolytic oxidation of aluminium, and wherein said ceramic material has a hardness according to Vickers (HV) of at least 750 measured according to DIN EN ISO 6507.
A device comprising: a circuit board ; a filter component ; at least one wire electrically connected to the circuit board and passing through the filter component to extend off the circuit board; a filter component housing , the filter component being housed in the filter component housing ; a wire-to-board electrical connector coupled to the circuit board and electrically connecting the at least one wire that extends off the circuit board to the circuit board; and a mount that is attached to the circuit board and that acts an intermediary member between the filter component housing and the circuit board coupling the filter component housing to the circuit board , wherein the mount surrounds the wire-to-board electrical connector and the filter component housing is reversibly coupled to the mount. a circuit board ; a filter component ; at least one wire electrically connected to the circuit board and passing through the filter component to extend off the circuit board; a filter component housing , the filter component being housed in the filter component housing ; a wire-to-board electrical connector coupled to the circuit board and electrically connecting the at least one wire that extends off the circuit board to the circuit board; and a mount that is attached to the circuit board and that acts an intermediary member between the filter component housing and the circuit board coupling the filter component housing to the circuit board , wherein the mount surrounds the wire-to-board electrical connector and the filter component housing is reversibly coupled to the mount.
A venting valve for venting the interior of a vehicle, comprising a housing having at least one passage opening , and comprising at least one venting flap which is mounted on the housing by means of a pivot mounting so as to be pivotable between a closed position and an open position, wherein, in the closed position, the at least one venting flap closes off the at least one passage opening and, in the open position, opens up the at least one passage opening for an air stream from the interior of the vehicle to the outside, wherein the pivot mounting is arranged on an inner side of the housing , which inner side, in the assembled state, faces the interior of the vehicle, wherein the pivot mounting comprises at least one pivot arm which is connected to the at least one venting flap and is pivotably articulated on at least one pivot bearing arranged on the inner side of the housing , wherein, in the closed position of the at least one venting flap , the at least one pivot arm guides in the direction of at least one venting flap an air stream coming from the vehicle interior, and wherein, in the open position, the at least one pivot arm guides in the direction of at least one passage opening of the housing an air stream coming from the vehicle interior.
A composition comprising an IL-13Rα2 peptide and an EphA2 peptide for use in a method of treating, preventing, or managing cancer in a subject in need thereof comprising (i) administering said composition to said subject and (ii) measuring the amount of cancer stem cells in said subject. (i) administering said composition to said subject and (ii) measuring the amount of cancer stem cells in said subject.
A device for continuously monitoring temperature of an artificially-created cavity in living body tissue that is bounded by a first hole in body tissue and a second hole in body tissue opposite the first hole, wherein the device comprises a distal portion and a proximal portion, wherein: the distal portion comprises: a body piercing device post for a body piercing device, the body piercing device post being configured for insertion and to be worn in an artificially-created cavity, said body piercing device post being dimensioned to be inserted into the artificially-created body tissue cavity, the body piercing device post comprising a means to sense temperature and provide a temperature measurement signal continuously or periodically using specified time intervals; and a spherical housing containing a transmitter configured to wirelessly transmit said temperature measurements continuously or periodically to a remote receiver for recording, the spherical housing being located at the distal end of the distal portion and being configured to be located outside of the first hole of the artificially-created cavity ; the proximal portion further comprises: a removable proximal portion that is removably attached to the body piercing device post at the further end from the transmitter and that is configured to be located outside of the second hole of the artificially-created cavity ; and the device further comprising: at least one power supply that powers said temperature sensor and said transmitter . a body piercing device post for a body piercing device, the body piercing device post being configured for insertion and to be worn in an artificially-created cavity, said body piercing device post being dimensioned to be inserted into the artificially-created body tissue cavity, the body piercing device post comprising a means to sense temperature and provide a temperature measurement signal continuously or periodically using specified time intervals; and a spherical housing containing a transmitter configured to wirelessly transmit said temperature measurements continuously or periodically to a remote receiver for recording, the spherical housing being located at the distal end of the distal portion and being configured to be located outside of the first hole of the artificially-created cavity ; the proximal portion further comprises: a removable proximal portion that is removably attached to the body piercing device post at the further end from the transmitter and that is configured to be located outside of the second hole of the artificially-created cavity ; and
A corrosion inhibition coating, comprising: a base comprising a matrix and a metal within the matrix; and an inhibitor comprising: zinc molybdate, cerium citrate, magnesium metasilicate, a metal phosphate silicate, or a combination thereof, wherein the metal within the matrix comprises aluminum, an aluminum alloy, zinc, a zinc alloy, magnesium, a magnesium alloy, or a combination thereof, wherein the base and the inhibitor are two distinct layers, wherein the inhibitor is coated on the base, further comprising a second matrix distinct from the base matrix, wherein the inhibitor is mixed within the second matrix. a base comprising a matrix and a metal within the matrix; and an inhibitor comprising: zinc molybdate, cerium citrate, magnesium metasilicate, a metal phosphate silicate, or a combination thereof, zinc molybdate, cerium citrate, magnesium metasilicate, a metal phosphate silicate, or a combination thereof, wherein the metal within the matrix comprises aluminum, an aluminum alloy, zinc, a zinc alloy, magnesium, a magnesium alloy, or a combination thereof, wherein the base and the inhibitor are two distinct layers, wherein the inhibitor is coated on the base, further comprising a second matrix distinct from the base matrix, wherein the inhibitor is mixed within the second matrix.
An access point of a wireless local area network, wherein an OFDMA time-frequency channel resource of the wireless local area network is divided into multiple child resources in a frequency domain, said child resources corresponding to orthogonal time-frequency resource blocks or resource block groups, wherein resource blocks are orthogonal in frequency and can be shared in time, and the access point comprises: a receiving unit , configured to receive resource status information sent by a station , wherein the resource status information indicates a busy/idle state of each of the child resources on the station ; an allocation unit , configured to allocate, according to the resource status information, the child resource used to transmit data between the access point and the station , and a sending unit , configured to send configuration information of the resource status information to the station , said configuration information including resource block group granularity indication information, wherein the resource block group granularity indication information indicates the number of resource blocks included by a resource block group, wherein the configuration information is used to instruct the station to determine the resource status information according to the configuration information. a receiving unit , configured to receive resource status information sent by a station , wherein the resource status information indicates a busy/idle state of each of the child resources on the station ; an allocation unit , configured to allocate, according to the resource status information, the child resource used to transmit data between the access point and the station , and a sending unit , configured to send configuration information of the resource status information to the station , said configuration information including resource block group granularity indication information, wherein the resource block group granularity indication information indicates the number of resource blocks included by a resource block group, wherein the configuration information is used to instruct the station to determine the resource status information according to the configuration information.
A thermosiphon system for cooling electronic devices, comprising: an evaporator ; a condenser comprising a plurality of parallel vertically-extending chambers , wherein: the chambers have closed off top ends, the condenser comprises a bottom header and a plurality of condensate tubes projecting upwardly from the bottom header, the plurality of parallel vertically-extending chambers is located within the plurality of condensate tubes; the parallel vertically-extending chambers provide an interior volume bounded by interior surfaces; the interior surfaces include undulations forming a sinusoidal wave and projecting inwardly into the interior volume, wherein the undulations are formed by a plurality of curved segments in which dK/dS is equal to a constant value, where K is an inverse of the radius of curvature of the undulation and S is a distance along the curved segment; and the thermosiphon system further comprises a condensate line fluidically coupling the condenser to the evaporator. an evaporator ; a condenser comprising a plurality of parallel vertically-extending chambers , wherein: the chambers have closed off top ends, the condenser comprises a bottom header and a plurality of condensate tubes projecting upwardly from the bottom header, the plurality of parallel vertically-extending chambers is located within the plurality of condensate tubes; the parallel vertically-extending chambers provide an interior volume bounded by interior surfaces; the interior surfaces include undulations forming a sinusoidal wave and projecting inwardly into the interior volume, wherein the undulations are formed by a plurality of curved segments in which dK/dS is equal to a constant value, the chambers have closed off top ends, the condenser comprises a bottom header and a plurality of condensate tubes projecting upwardly from the bottom header, the plurality of parallel vertically-extending chambers is located within the plurality of condensate tubes; the parallel vertically-extending chambers provide an interior volume bounded by interior surfaces; the interior surfaces include undulations forming a sinusoidal wave and projecting inwardly into the interior volume, wherein the undulations are formed by a plurality of curved segments in which dK/dS is equal to a constant value, where K is an inverse of the radius of curvature of the undulation and S is a distance along the curved segment; and the thermosiphon system further comprises a condensate line fluidically coupling the condenser to the evaporator.
A method comprising using at least one processor to: rasterize a seed image; and generate a plurality of rasterized modified images from the rasterized seed image, where generating each rasterized modified image comprises: determining an image attribute modification; and applying, using a processor, the determined image attribute modification to at least a portion of the rasterized seed image to generate the rasterized modified image. rasterize a seed image; and generate a plurality of rasterized modified images from the rasterized seed image, where generating each rasterized modified image comprises: determining an image attribute modification; and applying, using a processor, the determined image attribute modification to at least a portion of the rasterized seed image to generate the rasterized modified image. determining an image attribute modification; and applying, using a processor, the determined image attribute modification to at least a portion of the rasterized seed image to generate the rasterized modified image.
Microtome having a cutting knife , an object holder mounted on a slide , the slide being movable relative to the cutting knife in a cutting direction and in a thickness defining direction, movement of the slide in the thickness defining direction being performed by a first electric motor controlled by a control unit, movement of the slide in the cutting direction being performed by a second electric motor controlled by the control unit, wherein the control unit is configured to control the movement of the slide in the thickness defining direction and in the cutting direction, wherein the control unit is configured to provide a memory position, and to move the slide in the thickness defining direction into the memory position in reaction to a corresponding command, wherein the memory position is a position horizontally apart from the cutting knife , wherein the control unit is configured to trigger image taking after a section when the slide is in the memory position. a cutting knife , an object holder mounted on a slide , the slide being movable relative to the cutting knife in a cutting direction and in a thickness defining direction, movement of the slide in the thickness defining direction being performed by a first electric motor controlled by a control unit, movement of the slide in the cutting direction being performed by a second electric motor controlled by the control unit, wherein the control unit is configured to control the movement of the slide in the thickness defining direction and in the cutting direction, wherein the control unit is configured to provide a memory position, and to move the slide in the thickness defining direction into the memory position in reaction to a corresponding command, wherein the memory position is a position horizontally apart from the cutting knife , wherein the control unit is configured to trigger image taking after a section when the slide is in the memory position.