An orthopedic device , comprising: a body having a monolithic structure and arranged to form a closed circumference in a secured configuration, the body having a predetermined shape in an unsecured configuration; wherein the body is formed continuously without interruption from at least one polymeric material, the body defining a band disposed about a periphery of the body , the band enclosing at least one fenestration region defining at least two fenestrations formed by the body and arranged in a predetermined pattern the body defining at least one rib extending from the band and adjacent to the at least one fenestration region , the at least one rib exhibiting greater rigidity than the at least one fenestration region , the body defining a thumb column sized and configured for supporting a thumb; wherein the band and the at least one rib combine to form a frame that extends around the at least one fenestration region , such that the frame is substantially more rigid than the at least one fenestration region , the frame having a varying width about the periphery of the body ; wherein the body defines an opening bordered by the at least one rib and the band , and formed along a wall of the body , the opening being greater in size than the at least two fenestrations of the at least two fenestration regions , the opening located within a length of the thumb column , the thumb column defines an outlet from which a portion of a distal phalange of the thumb extends, the orthopedic device being characterised by the thumb Column defining a lip extending about the opening and having a greater thickness than the at least one rib and/or band . a body having a monolithic structure and arranged to form a closed circumference in a secured configuration, the body having a predetermined shape in an unsecured configuration; wherein the body is formed continuously without interruption from at least one polymeric material, the body defining a band disposed about a periphery of the body , the band enclosing at least one fenestration region defining at least two fenestrations formed by the body and arranged in a predetermined pattern the body defining at least one rib extending from the band and adjacent to the at least one fenestration region , the at least one rib exhibiting greater rigidity than the at least one fenestration region , the body defining a thumb column sized and configured for supporting a thumb; wherein the band and the at least one rib combine to form a frame that extends around the at least one fenestration region , such that the frame is substantially more rigid than the at least one fenestration region , the frame having a varying width about the periphery of the body ; wherein the body defines an opening bordered by the at least one rib and the band , and formed along a wall of the body , the opening being greater in size than the at least two fenestrations of the at least two fenestration regions , the opening located within a length of the thumb column , the thumb column defines an outlet from which a portion of a distal phalange of the thumb extends, the orthopedic device being characterised by the thumb Column defining a lip extending about the opening and having a greater thickness than the at least one rib and/or band . <EOS>