A dosing syringe assembly comprising: a syringe barrel comprising an inner chamber filled or adapted to be filled with medicament, and a channel in fluid communication with the chamber and through which medicament is dispensed; and an end cap configured to be removably attached to the syringe barrel , wherein the barrel comprises an internal threaded section which mutually engages with a threaded section on the end cap to thereby create a seal, which prevents the flow of medicament therethrough, characterised in that : the syringe assembly is a single unit dose syringe assembly pre-filled with medicament; the end cap comprises a body with at least two mutually opposing projections , which extend transversely therefrom and which are configured to facilitate removal of the cap from the barrel; the syringe barrel is incompatible with a Luer lock, or a Luer slip; the syringe barrel does not comprise an external screw thread at least adjacent or towards the end of the barrel from which medicament is dispensed; the syringe assembly comprises a plunger configured to slide in the chamber , which plunger comprises a rod ; and the syringe assembly comprises a transversely extending projection disposed on the side of the plunger rod , and an indentation disposed along the inside of the chamber , or vice versa, wherein alignment of the projection and indentation correlates with a defined volume of medicament and thereby a dosage. a syringe barrel comprising an inner chamber filled or adapted to be filled with medicament, and a channel in fluid communication with the chamber and through which medicament is dispensed; and an end cap configured to be removably attached to the syringe barrel , wherein the barrel comprises an internal threaded section which mutually engages with a threaded section on the end cap to thereby create a seal, which prevents the flow of medicament therethrough, characterised in that : the syringe assembly is a single unit dose syringe assembly pre-filled with medicament; the end cap comprises a body with at least two mutually opposing projections , which extend transversely therefrom and which are configured to facilitate removal of the cap from the barrel; the syringe barrel is incompatible with a Luer lock, or a Luer slip; the syringe barrel does not comprise an external screw thread at least adjacent or towards the end of the barrel from which medicament is dispensed; the syringe assembly comprises a plunger configured to slide in the chamber , which plunger comprises a rod ; and the syringe assembly comprises a transversely extending projection disposed on the side of the plunger rod , and an indentation disposed along the inside of the chamber , or vice versa, wherein alignment of the projection and indentation correlates with a defined volume of medicament and thereby a dosage. the syringe assembly is a single unit dose syringe assembly pre-filled with medicament; the end cap comprises a body with at least two mutually opposing projections , which extend transversely therefrom and which are configured to facilitate removal of the cap from the barrel; the syringe barrel is incompatible with a Luer lock, or a Luer slip; the syringe barrel does not comprise an external screw thread at least adjacent or towards the end of the barrel from which medicament is dispensed; the syringe assembly comprises a plunger configured to slide in the chamber , which plunger comprises a rod ; and the syringe assembly comprises a transversely extending projection disposed on the side of the plunger rod , and an indentation disposed along the inside of the chamber , or vice versa, wherein alignment of the projection and indentation correlates with a defined volume of medicament and thereby a dosage. <EOS>