mhurhangee/patent-ind-claim-en huggingface dataset:
A composition comprising: a CRISPR Type VI RNA-targeting effector protein; at least one guide polynucleotide comprising a guide sequence capable of hybridizing with a target nucleic acid sequence, and designed to form a complex with the CRISPR Type VI RNA-targeting effector protein; an RNA-based masking construct, and the composition further comprises an RNA polymerase and nucleic acid amplification reagents comprising a primer designed to bind the target nucleic acid sequence and further comprising an RNA polymerase promoter. a CRISPR Type VI RNA-targeting effector protein; at least one guide polynucleotide comprising a guide sequence capable of hybridizing with a target nucleic acid sequence, and designed to form a complex with the CRISPR Type VI RNA-targeting effector protein; an RNA-based masking construct,
An isolated humanized monoclonal antibody or antigen-binding fragment thereof comprising: (i) H-CDR1 having the sequence of FSLTSYGVS; (ii) H-CDR2 having the sequence of GVIWGEGSTNYHSVLISRL; and (iii) H-CDR3 having the sequence AMTGTAY, respectively; and comprising: (iv) L-CDR1 having the sequence of SASSSVSYMH; (v) L-CDR2 having the sequence of DTSKLSS; and (vi) L-CDR3 having the sequence of HQWSSSPHT, respectively, wherein the isolated humanized monoclonal antibody or the antigen-binding fragment further comprises: (i) H-FR1 having the sequence of QVQLQESGPGLVKPSETLSLTCTVSG; (ii) H-FR2 having the sequence of WIRQPPGKGLEWI; (iii) H-FR3 having the sequence of TISKDNSKSQVFLKLNSLQTDDTATYYC; (iv) H-FR4 having the sequence of WGQGTLVTVSS, respectively; and (v) L-FR1 having the sequence of QIVLTQSPAIMSASPGEKVTMTC; (vi) L-FR2 having the sequence of WYQQKPGLAPRLLIY; (vii) L-FR3 having the sequence of GVPGRFSGSGSGTSYSLTISRLEAEDAATYYC, (viii) L-FR4 having the sequence of FGGGTKVEIKR, respectively. (i) H-CDR1 having the sequence of FSLTSYGVS; (ii) H-CDR2 having the sequence of GVIWGEGSTNYHSVLISRL; and (iii) H-CDR3 having the sequence AMTGTAY, respectively; (iv) L-CDR1 having the sequence of SASSSVSYMH; (v) L-CDR2 having the sequence of DTSKLSS; and (vi) L-CDR3 having the sequence of HQWSSSPHT, respectively, (i) H-FR1 having the sequence of QVQLQESGPGLVKPSETLSLTCTVSG; (ii) H-FR2 having the sequence of WIRQPPGKGLEWI; (iii) H-FR3 having the sequence of TISKDNSKSQVFLKLNSLQTDDTATYYC; (iv) H-FR4 having the sequence of WGQGTLVTVSS, respectively; and (v) L-FR1 having the sequence of QIVLTQSPAIMSASPGEKVTMTC; (vi) L-FR2 having the sequence of WYQQKPGLAPRLLIY; (vii) L-FR3 having the sequence of GVPGRFSGSGSGTSYSLTISRLEAEDAATYYC, (viii) L-FR4 having the sequence of FGGGTKVEIKR, respectively.
A flame-retardant polybutylene terephthalate resin composition containing a polybutylene terephthalate resin and a halogenated benzyl acrylate-based flame retardant in which the content of a protic compound is 10-1,000 ppm as measured by headspace gas chromatography (180°C, 1 hour heating), wherein the protic compound is an alkoxy alcohol or an aromatic carboxylic acid, and the aromatic carboxylic acid is derived from a raw material of the halogenated benzyl acrylate-based flame retardant, and wherein the polybutylene terephthalate resin comprises 50-1,000 ppm of a linear low-molecular weight-body, determined as indicated in the description, and wherein the linear low-molecular weight-body is an oligomer of the polybutylene terephthalate.
A compound having the formula N-(4-{[4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl]oxylbutyl)octadecanamide, or a pharmaceutically acceptable salt thereof, for use in treating a viral, bacterial, fungal, or parasitic disease.
Method for controlling drying of wood in a compartment , the method comprising subjecting the wood to altering periods of hard drying and soft drying, repeatedly during drying of wood , receiving a measured value of an amount of condense water per time unit derived from air circulating through the wood during the drying, determining a control parameter value based at least on the measured value, controlling the drying of wood using the control parameter value, wherein the control parameter is for controlling of heating, of air flow within the compartment, or venting of air to or from the compartment, or combinations thereof and wherein the control parameter is for initiating the altering of periods of hard and soft drying and/or, during altering periods of hard and soft drying, for altering the drying from hard to soft drying and/or from soft to hard drying. subjecting the wood to altering periods of hard drying and soft drying, repeatedly during drying of wood , receiving a measured value of an amount of condense water per time unit derived from air circulating through the wood during the drying, determining a control parameter value based at least on the measured value, controlling the drying of wood using the control parameter value, wherein the control parameter is for controlling of heating, of air flow within the compartment, or venting of air to or from the compartment, or combinations thereof and wherein the control parameter is for initiating the altering of periods of hard and soft drying and/or, during altering periods of hard and soft drying, for altering the drying from hard to soft drying and/or from soft to hard drying.
A cam isolation system for a gas turbine engine compressor actuator comprising: a torque tube ; a cam bracket operatively coupled to an engine case structure , the cam bracket defining a slot ; and an actuator bracket operatively coupled to the torque tube at a first end of the actuator bracket, the actuator bracket having a pin disposed within the slot of the cam bracket; and wherein the cam bracket includes a first cam bracket side and a second cam bracket side , the first cam bracket side defining a first slot and the second cam bracket side defining a second slot , the actuator bracket having a first pin extending from a first side of the actuator bracket and into the first slot, the actuator bracket having a second pin extending from a second side of the actuator bracket and into the second slot. a torque tube ; a cam bracket operatively coupled to an engine case structure , the cam bracket defining a slot ; and an actuator bracket operatively coupled to the torque tube at a first end of the actuator bracket, the actuator bracket having a pin disposed within the slot of the cam bracket; and wherein the cam bracket includes a first cam bracket side and a second cam bracket side , the first cam bracket side defining a first slot and the second cam bracket side defining a second slot , the actuator bracket having a first pin extending from a first side of the actuator bracket and into the first slot, the actuator bracket having a second pin extending from a second side of the actuator bracket and into the second slot.
A catheter of an intravascular blood pump (P) for percutaneous insertion into a patient's blood vessel, the catheter having an elongate tubular body which extends between a proximal end and a distal end of the catheter and has an outer surface , the catheter characterised by including a porous three-dimensional structure on at least a portion of the outer surface which is located in the patient's blood vessel during operation of the blood pump (P), wherein the porous three-dimensional structure is directly formed onto the tubular body of the catheter , preferably by electrospinning or spraying.
A tank assembly comprising a tank for a heat exchanger, in particular for a motor vehicle, comprising: - a distribution body for delivering a coolant fluid into the heat exchanger; - a first opening disposed along the longitudinal direction of the distribution body , the first opening having a substantially rectangular shape for receiving a header with tubes; - a second opening disposed on the surface of the distribution body , the second opening having a circular shape; - at least one guiding means disposed in the vicinity of the second opening , and - a connector comprising at least one protruding portion cooperating with the guiding means , the connector being configured to be assembled with the tank , wherein the guiding means and the protruding portion are configured to engage the connector with the tank in a first angular position to prevent the connector from moving in the axis of the second opening , and to disengage the connector from the tank in a second angular position in the plane delimited by the second opening , wherein the guiding means comprise a guide and the protruding portion comprise a protrusion , wherein one of them is located on the tank and a second one is located on the connector , wherein the protrusion is adapted to be engaged in the guide , thereby restricting movement of the connector in the axis of the second opening , wherein the guide is configured to releasably fix the connector in the first angular position, characterised in that the protruding portion is in a form of a winglet , the winglet being of a flatted shape and comprising a slope configured to interact with the guide . - a distribution body for delivering a coolant fluid into the heat exchanger; - a first opening disposed along the longitudinal direction of the distribution body , the first opening having a substantially rectangular shape for receiving a header with tubes; - a second opening disposed on the surface of the distribution body , the second opening having a circular shape; - at least one guiding means disposed in the vicinity of the second opening , and - a connector comprising at least one protruding portion cooperating with the guiding means , the connector being configured to be assembled with the tank , wherein the guiding means and the protruding portion are configured to engage the connector with the tank in a first angular position to prevent the connector from moving in the axis of the second opening , and to disengage the connector from the tank in a second angular position in the plane delimited by the second opening , wherein the guiding means comprise a guide and the protruding portion comprise a protrusion , wherein one of them is located on the tank and a second one is located on the connector , wherein the protrusion is adapted to be engaged in the guide , thereby restricting movement of the connector in the axis of the second opening , wherein the guide is configured to releasably fix the connector in the first angular position, characterised in that the protruding portion is in a form of a winglet , the winglet being of a flatted shape and comprising a slope configured to interact with the guide .
Entity of a drive gear and a two-stage planetary gear for a transfer case of a motor vehicle, the planetary gear comprising an input shaft , a planet-gear carrier having planet gears , a ring gear , a sun gear , and an axially displaceable shift collar , wherein the shift collar is connected in a rotationally fixed manner to the input shaft , wherein the shift collar in a first terminal position couples the input shaft in a rotationally fixed manner to the sun gear , and in a second terminal position couples the input shaft in a rotationally fixed manner to the planet-gear carrier , characterized in that the sun gear is mounted so as to be rotatable on the input shaft , and the planetary gear is disposed so as to be concentric within the drive gear .
An orthotic for a foot having a top side and a bottom side as well as a medial side and a lateral side, comprising: a flexion zone (zone 8) in the bottom side of the orthotic located between the medial and the lateral side of the orthotic at a position corresponding to the location between a metatarsal phalangeal joint of the foot to 25mm behind the phalangeal joint, and/or a heel section (zone 7) in the bottom side of the orthotic which is pitched so that the height of the rear of the orthotic is greater than the height of the front of the heel section (zone 7); and further comprising a raised section in the top side of the orthotic located at a position corresponding to the cuboid area of the lateral side of the foot and extending in the anterior direction along one third of the shaft of the fifth metatarsal (zone 2), and/or a fascial groove located at a position corresponding to the area between the medial tubercle of the calcaneus to the insertion point of the medial cuneiform into the base of the first metatarsal (zone 3), wherein the top side of the orthotic further has a raised section located at a position corresponding to the medial side of the calcaneus of the foot (zone 1), and an indentation located at a position corresponding to the base of the first metatarsal of the foot (zone 4). a flexion zone (zone 8) in the bottom side of the orthotic located between the medial and the lateral side of the orthotic at a position corresponding to the location between a metatarsal phalangeal joint of the foot to 25mm behind the phalangeal joint, and/or a heel section (zone 7) in the bottom side of the orthotic which is pitched so that the height of the rear of the orthotic is greater than the height of the front of the heel section (zone 7); and further comprising a raised section in the top side of the orthotic located at a position corresponding to the cuboid area of the lateral side of the foot and extending in the anterior direction along one third of the shaft of the fifth metatarsal (zone 2), and/or a fascial groove located at a position corresponding to the area between the medial tubercle of the calcaneus to the insertion point of the medial cuneiform into the base of the first metatarsal (zone 3), wherein the top side of the orthotic further has a raised section located at a position corresponding to the medial side of the calcaneus of the foot (zone 1), and an indentation located at a position corresponding to the base of the first metatarsal of the foot (zone 4).
An external rearview assembly comprising: a housing pivotally coupled with a vehicle door and operable between an extended position and a retracted position ; an electro-optic element operably coupled with the housing , wherein the electro-optic element is heated and configured to darken when the housing is in the extended position and lighten when the housing is in the retracted position ; a display module disposed proximate the electro-optic element , wherein the display module is activated when the housing is in the retracted position , and wherein the display module is deactivated when the housing is in the extended position ; and an imager operably coupled with the housing and configured to capture image data when the housing is in the retracted position and display the image data on the activated display module . a housing pivotally coupled with a vehicle door and operable between an extended position and a retracted position ; an electro-optic element operably coupled with the housing , wherein the electro-optic element is heated and configured to darken when the housing is in the extended position and lighten when the housing is in the retracted position ; a display module disposed proximate the electro-optic element , wherein the display module is activated when the housing is in the retracted position , and wherein the display module is deactivated when the housing is in the extended position ; and an imager operably coupled with the housing and configured to capture image data when the housing is in the retracted position and display the image data on the activated display module .
A color information processing method comprising: inputting reference data including color information about each pixel or each pixel group of a reference medium and evaluation target data including color information about each pixel or each pixel group of an evaluation medium by an input means , wherein the reference medium is a printed matter and the evaluation medium is a printed matter, the reference data and the evaluation target data are obtained by input the reference medium and the evaluation medium by an image input equipment ; and performing an image matching process of image matching the input reference data and evaluation target data by an image processing means comprising positioning the images of the reference medium and the evaluation medium on a common coordinate axis of the images and removing a relative size difference and relative distortion, such that pixel levels thereof correspond to each other; characterized by setting a specific area which is a unit of evaluation and includes a plurality of pixel groups to each data item subjected to the image matching process by an area setting means , the specific area being able to arbitrarily be set by an operator; and comparing average color information items for each pixel group in the reference data and the evaluation target data in the set specific area to calculate a pixel group color difference and performing an averaging process to average the calculated pixel group color differences over the specific area to calculate an average evaluation result for the specific area by a calculation means . inputting reference data including color information about each pixel or each pixel group of a reference medium and evaluation target data including color information about each pixel or each pixel group of an evaluation medium by an input means , wherein the reference medium is a printed matter and the evaluation medium is a printed matter, the reference data and the evaluation target data are obtained by input the reference medium and the evaluation medium by an image input equipment ; and performing an image matching process of image matching the input reference data and evaluation target data by an image processing means comprising positioning the images of the reference medium and the evaluation medium on a common coordinate axis of the images and removing a relative size difference and relative distortion, such that pixel levels thereof correspond to each other; characterized by setting a specific area which is a unit of evaluation and includes a plurality of pixel groups to each data item subjected to the image matching process by an area setting means , the specific area being able to arbitrarily be set by an operator; and comparing average color information items for each pixel group in the reference data and the evaluation target data in the set specific area to calculate a pixel group color difference and performing an averaging process to average the calculated pixel group color differences over the specific area to calculate an average evaluation result for the specific area by a calculation means .
A method of controlling an LED fixture comprising a plurality of LEDs , the plurality of LED comprising at least four LEDs, configured to emit light of different colors, the method comprising: - receiving a plurality of set points , each representing a desired color at a desired intensity for the light to be generated by the LED fixture; - determining , based on available color characteristics of the plurality of LEDs, at least two different subsets of the plurality of LEDs and a set of intensity set points for each of the at least two different subsets, wherein each set of intensity set points results in obtaining or approximating the desired color at the desired intensity of more than one of the plurality of set points by the LED fixture; - selecting one or more of the subsets of the plurality of LEDs with the corresponding set of intensity set points which meets a predetermined criterion; - using the one or more selected subsets to drive the plurality of LEDs with the corresponding set of intensity set points, whereby the predetermined criterion comprises a capability of realising the plurality of set points or a subset thereof. - receiving a plurality of set points , each representing a desired color at a desired intensity for the light to be generated by the LED fixture; - determining , based on available color characteristics of the plurality of LEDs, at least two different subsets of the plurality of LEDs and a set of intensity set points for each of the at least two different subsets, wherein each set of intensity set points results in obtaining or approximating the desired color at the desired intensity of more than one of the plurality of set points by the LED fixture; - selecting one or more of the subsets of the plurality of LEDs with the corresponding set of intensity set points which meets a predetermined criterion; - using the one or more selected subsets to drive the plurality of LEDs with the corresponding set of intensity set points, whereby the predetermined criterion comprises a capability of realising the plurality of set points or a subset thereof.
A recombinant fusion protein comprising a spidroin fragment and a cell-binding motif with selectivity for integrins, wherein the cell-binding motif is comprising the amino acid sequence C 1 X 1 X 2 RGDX 3 X 4 X 5 C 2 wherein X 1 is S or T; X 2 is G, A or V; X 3 is S or T; X 4 is G, A, V or P; and X 5 is G, A or V; and C 1 and C 2 are connected via a disulphide bond; and wherein the spidroin fragment is comprising the protein moiety CT, wherein CT is a fragment of from 70 to 120 amino acid residues, having at least 70% identity to any one of SEQ ID NO: 3 and 29-59. X 1 is S or T; X 2 is G, A or V; X 3 is S or T; X 4 is G, A, V or P; and X 5 is G, A or V; and
Heating apparatus having a combustion chamber that has a bottom (12.1), lateral walls (12.2 to 12.5) and an upper opening closed off by at least one removable plate , the heating apparatus also having a first circuit configured to convey combustion products from the combustion chamber to an exhaust duct , the heating apparatus comprising: - at least one air circuit for supplying the combustion chamber with air and having at least two air injection manifolds comprising one or more segments comprising injection orifices , which open into the combustion chamber , are separated from one another by a distance of less than or equal to 5 cm, and extend over at least 30% of the periphery of the combustion chamber , - a first enclosure around the combustion chamber , said first enclosure being spaced apart from at least some of the lateral walls (12.2 to 12.5) of the combustion chamber so as to form the first circuit for circulating combustion products from the combustion chamber to the exhaust duct , the combustion chamber comprising the first air injection manifold , positioned between 0.4 and 0.75 times the height of the combustion chamber from the bottom (12.1) of the combustion chamber , and the second air injection manifold positioned adjoining the bottom (12.1) of the combustion chamber, the orifices of said second air injection manifold being spaced apart from the bottom (12.1) of the combustion chamber . - at least one air circuit for supplying the combustion chamber with air and having at least two air injection manifolds comprising one or more segments comprising injection orifices , which open into the combustion chamber , are separated from one another by a distance of less than or equal to 5 cm, and extend over at least 30% of the periphery of the combustion chamber , - a first enclosure around the combustion chamber , said first enclosure being spaced apart from at least some of the lateral walls (12.2 to 12.5) of the combustion chamber so as to form the first circuit for circulating combustion products from the combustion chamber to the exhaust duct , the combustion chamber comprising the first air injection manifold , positioned between 0.4 and 0.75 times the height of the combustion chamber from the bottom (12.1) of the combustion chamber , and the second air injection manifold positioned adjoining the bottom (12.1) of the combustion chamber, the orifices of said second air injection manifold being spaced apart from the bottom (12.1) of the combustion chamber .