mhurhangee/patent-ind-claim-en huggingface dataset:
A liquid forming and filling system for forming and filling a container with a liquid, the liquid forming and filling system comprising: a motor ; a gear box operably coupled to the motor configured to receive a driving output from the motor and outputting a gear box driving force; a linear screw operably coupled to the gear box configured to produce linear movement in response to rotational movement from the gear box ; a forming cylinder configured to output pressurized liquid for forming and filling the container, the forming cylinder being in an inverted orientation; the system being characterized by a top manifold plate and end cap vent valve assembly coupled to the forming cylinder for receiving the pressurize liquid; and a vent valve operably coupled to the top manifold plate and end cap vent valve assembly configured to vent air entrapped within the pressurized liquid. a motor ; a gear box operably coupled to the motor configured to receive a driving output from the motor and outputting a gear box driving force; a linear screw operably coupled to the gear box configured to produce linear movement in response to rotational movement from the gear box ; a forming cylinder configured to output pressurized liquid for forming and filling the container, the forming cylinder being in an inverted orientation; the system being characterized by a top manifold plate and end cap vent valve assembly coupled to the forming cylinder for receiving the pressurize liquid; and a vent valve operably coupled to the top manifold plate and end cap vent valve assembly configured to vent air entrapped within the pressurized liquid.
A compound for use in treating metastasizing cancer in a human being, wherein said compound comprises a peptide of the amino acid sequence X 1 -R-W-H-X 5 , wherein X 1 is selected from K, R, N, or Q and wherein X 5 is selected from E or D, wherein said metastasizing cancer shows expression of CD44v6, and wherein said treating causes regression of metastases that have already formed and spread across the body.
A pharmaceutical kit for use in a method of treatment of a human patient suffering from non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC), malignant glioma, breast cancer, esophageal cancer, gastric cancer, renal cancer, cervical cancer, prostate cancer, ovarian cancer, pancreatic cancer, hepatocellular cancer or colorectal cancer (CRC), including metastatic forms thereof, comprising a first compartment which comprises an effective amount of a Human Epidermal Growth Factor Receptor (Human EGFR) targeted monoclonal antibody (mAB) selected from the group consisting of cetuximab, panitumumab, zalutumumab, nimotuzumab, matuzumab and necitumumab, and a second compartment which comprises an effective amount of the irreversible tyrosine kinase inhibitor (TKI) BIBW 2992 or a pharmaceutically acceptable salt thereof.
A compound of the following Formula 1, or a pharmaceutically acceptable salt or isomer thereof: wherein R1 is C 2 -C 5 alkyl; and wherein isomer refers to the cis or trans isomers, R or S isomers, racemates, diastereoisomer mixtures and individual diastereoisomers. wherein R1 is C 2 -C 5 alkyl; and wherein isomer refers to the cis or trans isomers, R or S isomers, racemates, diastereoisomer mixtures and individual diastereoisomers.
A long-acting prodrug of Rasagiline or solvate thereof, wherein the long-acting prodrug of Rasagiline has a structure of formula I: wherein one of: (a) T is absent, or T is selected from each of R 1 and R 2 is independently selected from H, D, or C 1 - 4 alkyl; W is absent, or W is selected from (CH 2 ) n , wherein n is an integer selected from 1 to 15; X is absent, or X is selected from (CH 2 ) m , wherein m is an integer selected from 1 to 10; and Y is absent, orY is selected from -C(=O)NH-, or -NHC(=O)-; R 3 is selected from: (i) a substituted cholane aliphatic group selected from or (ii) R 3 is -CH=CHR 4 , wherein R 4 is selected from phenyl substituted with one or more groups selected from OH, or alkoxy; or (b) W, and T are absent; X is selected from (CH 2 ) m , wherein m is an integer selected from 1 to 10; Y is selected from -C(=O)NH-, or -NHC(=O)-; and R 3 is selected from aryl, substituted C 1 -C 6 alkyl, or linear or branched, saturated or unsaturated C 7 -C 27 alkyl. wherein each substituted alkyl comprises 1, 2, 3 or 4 substituents independently selected from oxo (=O), thio (=S), F, Cl, amino, carbonyl, cycloalkyl, aryl, or heteroaryl. wherein one of: (a) T is absent, or T is selected from each of R 1 and R 2 is independently selected from H, D, or C 1 - 4 alkyl; W is absent, or W is selected from (CH 2 ) n , wherein n is an integer selected from 1 to 15; X is absent, or X is selected from (CH 2 ) m , wherein m is an integer selected from 1 to 10; and Y is absent, orY is selected from -C(=O)NH-, or -NHC(=O)-; R 3 is selected from: (i) a substituted cholane aliphatic group selected from or (ii) R 3 is -CH=CHR 4 , wherein R 4 is selected from phenyl substituted with one or more groups selected from OH, or alkoxy; or (b) W, and T are absent; X is selected from (CH 2 ) m , wherein m is an integer selected from 1 to 10; Y is selected from -C(=O)NH-, or -NHC(=O)-; and R 3 is selected from aryl, substituted C 1 -C 6 alkyl, or linear or branched, saturated or unsaturated C 7 -C 27 alkyl. wherein each substituted alkyl comprises 1, 2, 3 or 4 substituents independently selected from oxo (=O), thio (=S), F, Cl, amino, carbonyl, cycloalkyl, aryl, or heteroaryl.
A process for producing a crushed foam coating on a substrate comprising (a) introducing gas into an aqueous coating composition to produce a wet foam, (b) applying a layer of the wet foam to a substrate, (c) drying the layer of wet foam to a water content of 2% to 20% by weight, to produce a layer of dried foam, and (d) crushing the layer of dried foam to produce a layer of crushed dried foam, wherein the aqueous coating composition comprises one or more binder polymers and a collection of multi-stage copolymer particles having a core and a shell, having a weight average diameter of 2-20 μm, wherein said multi-stage copolymer particles are multi-stage graded refractive index (GRIN) copolymer particles comprising a core having a glass transition temperature (Tg) of 20°C or less, determined by differential scanning calorimetry (DSC) at 10°C, using the midpoint method. (a) introducing gas into an aqueous coating composition to produce a wet foam, (b) applying a layer of the wet foam to a substrate, (c) drying the layer of wet foam to a water content of 2% to 20% by weight, to produce a layer of dried foam, and (d) crushing the layer of dried foam to produce a layer of crushed dried foam,
A method for manufacturing a portable data carrier , wherein the portable data carrier contains a foil , an electronic component and an interface , wherein the foil serves as a carrier of at least one electronic component and at least one interface , characterized in that a transparent foil is used as the foil, wherein electrical conductor paths are printed on the foil by means of a transparent, electrically conductive material in order to electrically conductively connect the electronic component to the interface , wherein a cover is applied to the side of the foil opposite the electronic component such that the electronic component is not recognizable through the transparent foil .
Apparatus for cooling a structure , comprising: an assembly of configurable, thermally conductive cooling blocks configured to be placed against a surface of the structure and fit within a predetermined volume of space adjacent the structure , wherein the cooling blocks include interconnections coupling the cooling blocks together, wherein the interconnections are releasable to allow the shape of the assembly of the cooling blocks to be reconfigured. an assembly of configurable, thermally conductive cooling blocks configured to be placed against a surface of the structure and fit within a predetermined volume of space adjacent the structure , wherein the cooling blocks include interconnections coupling the cooling blocks together, wherein the interconnections are releasable to allow the shape of the assembly of the cooling blocks to be reconfigured.
System of statically loadable components for building structures comprising at least two different tension elements , each with at least one end region , having an outer thread in their end region , and at least one connecting component with an inner thread which is designed to interact with the outer thread of one of the tension elements as a tension member, characterised in that the outer threads of the at least two different tension elements have the same thread load rating and determine a respective limit tension load of the at least two different tension elements , wherein the outer thread can absorb less load than, or can absorb the same load as, the calculated breaking strength of the respective tension element . at least two different tension elements , each with at least one end region , having an outer thread in their end region , and at least one connecting component with an inner thread which is designed to interact with the outer thread of one of the tension elements as a tension member, characterised in that the outer threads of the at least two different tension elements have the same thread load rating and determine a respective limit tension load of the at least two different tension elements , wherein the outer thread can absorb less load than, or can absorb the same load as, the calculated breaking strength of the respective tension element .
A tandem photovoltaic cell, comprising: (A) at least one core semiconductor nanowire on a graphene layer, said at least one core nanowire having been grown epitaxially on said graphene layer wherein said nanowire comprises at least one group III-V compound; a semiconductor shell surrounding said core nanowire, said shell comprising at least one group III-V compound such that said core nanowire and said shell form an n-type semiconductor and a p-type semiconductor respectively or vice versa; further comprising: an outer conducting coating surrounding said shell which forms an electrode contact; or an outer conducting layer which contacts the top of the semiconductor shell on said nanowire and which forms an electrode; and (B) a thin-film p-n junction cell having a bottom electrode and a top electrode; wherein said graphene layer serves as the top electrode for the thin-film p-n junction cell. (A) at least one core semiconductor nanowire on a graphene layer, said at least one core nanowire having been grown epitaxially on said graphene layer wherein said nanowire comprises at least one group III-V compound; a semiconductor shell surrounding said core nanowire, said shell comprising at least one group III-V compound such that said core nanowire and said shell form an n-type semiconductor and a p-type semiconductor respectively or vice versa; further comprising: an outer conducting coating surrounding said shell which forms an electrode contact; or an outer conducting layer which contacts the top of the semiconductor shell on said nanowire and which forms an electrode; and a semiconductor shell surrounding said core nanowire, said shell comprising at least one group III-V compound such that said core nanowire and said shell form an n-type semiconductor and a p-type semiconductor respectively or vice versa; further comprising: an outer conducting coating surrounding said shell which forms an electrode contact; or an outer conducting layer which contacts the top of the semiconductor shell on said nanowire and which forms an electrode; and an outer conducting coating surrounding said shell which forms an electrode contact; or an outer conducting layer which contacts the top of the semiconductor shell on said nanowire and which forms an electrode; and (B) a thin-film p-n junction cell having a bottom electrode and a top electrode; wherein said graphene layer serves as the top electrode for the thin-film p-n junction cell.
Seed drill having a movable coulter carrier on which a multiplicity of sowing coulters are arranged, having a coulter pressure adjustment device for adjusting the coulter pressure of the sowing coulters , and having a coulter lifting device for lifting the sowing coulters out of a working position into a transport position by means of the coulter carrier, wherein the movement of the coulter carrier for setting the coulter pressure and the coulter lifting are brought about by a common assembly of the coulter pressure adjustment device and of the coulter lifting device , wherein the common assembly comprises at least one cylinder that is connected to at least one assembly each of the coulter lifting device and the coulter pressure adjustment device , wherein the cylinder is connected to the coulter lifting device and the coulter pressure adjustment device via a movable joint , comprising an adjustment lever and a distance lever connected movably thereto, wherein the joint and the cylinder form the common assembly, wherein the coulter pressure adjustment device comprises a first, rotatably mounted beam which is arranged transversely to the direction of travel of the seed drill and on which spring elements , connected to the sowing coulters, for changing the coulter pressure of the sowing coulters are arranged, characterized in that the coulter lifting device comprises a second beam , wherein the second beam is mounted in a movable manner and the beam being moved by the common assembly can bring about lifting of the coulter carrier, in that the adjusting lever of the joint is arranged so as to be rotatable about the second beam , wherein the second beam comprises a stop , wherein the joint moving against the stop can bring about lifting of the coulter carrier.
A stretching device for stretching a film made of a synthetic material, comprising: - a guide rail including a first guide surface (15.1) intended to be directed towards the film and a second guide surface (15.2) opposite to the first guide surface (15.1), - a plurality of first clamps and a plurality of second clamps each intended to grasp the same longitudinal edge of the film, the first and second clamps being disposed alternately along the guide rail and being configured to be guided by the guide rail , and - a first endless chain connected to the first clamps and configured to drive the first clamps along the guide rail , the stretching device further comprises a second endless chain connected to the second clamps and configured to drive the second clamps along the guide rail , the first and second endless chains being distinct from each other such that the first clamps are not mechanically connected to the second endless chain and such that the second clamps are not mechanically connected to the first endless chain, and in that the first and second endless chains are deformable between a first state in which the first and second clamps are disposed proximate to one another, and a second state in which the first and second clamps are away from one another. - a guide rail including a first guide surface (15.1) intended to be directed towards the film and a second guide surface (15.2) opposite to the first guide surface (15.1), - a plurality of first clamps and a plurality of second clamps each intended to grasp the same longitudinal edge of the film, the first and second clamps being disposed alternately along the guide rail and being configured to be guided by the guide rail , and - a first endless chain connected to the first clamps and configured to drive the first clamps along the guide rail , the stretching device further comprises a second endless chain connected to the second clamps and configured to drive the second clamps along the guide rail , the first and second endless chains being distinct from each other such that the first clamps are not mechanically connected to the second endless chain and such that the second clamps are not mechanically connected to the first endless chain, and in that the first and second endless chains are deformable between a first state in which the first and second clamps are disposed proximate to one another, and a second state in which the first and second clamps are away from one another.
A component , comprising: a first part having a first surface ; a second part having a second surface ; at least one shiplap interface formed between the first surface and the second surface, a brazed joint in the shiplap interface and joining the first part and the second part, the shiplap interface having a first corner and a second corner and a step surface disposed between the first corner and the second corner, the shiplap interface including a first cavity located at the first corner; the component characterised by a second cavity located at the second corner. a first part having a first surface ; a second part having a second surface ; at least one shiplap interface formed between the first surface and the second surface, a brazed joint in the shiplap interface and joining the first part and the second part, the shiplap interface having a first corner and a second corner and a step surface disposed between the first corner and the second corner, the shiplap interface including a first cavity located at the first corner; the component characterised by a second cavity located at the second corner.
Control device (DC) for a vehicle (V) comprising - i) a gearbox (BV) of the automatic type with planetary gear sets (TEj) defining ratios and each associated with a clutch (EMj) comprising a piston (Pj) exerting pressure on discs (DEj), and - ii) a prime mover (MT) supplying engine torque to said gearbox (BV), - iii) control means (MC) which, when a change from an outgoing gear to an incoming gear has been decided, determine a pressure to be exerted by the piston (Pj) associated with the incoming gear in order to fully transmit the engine torque, characterized in that the control means (MC) control: - either the engine torque at a torque setpoint value and the pressure at an optimum pressure to fully transmit the torque setpoint when an oil temperature in the gearbox (BV) is lower than a first chosen threshold and that a number of cumulative uses of the clutch (EMj) containing this piston (Pj) since the commissioning of the vehicle is less than a second chosen threshold, - either the engine torque at a reduced torque setpoint value and the pressure at a reduced pressure to fully transmit the reduced torque setpoint when the oil temperature is higher than the first chosen threshold or when the number of uses is higher than the second threshold chosen, the reduced torque setpoint value being equal to the torque setpoint value less a determined value and the reduced pressure being lower than the optimum pressure. - i) a gearbox (BV) of the automatic type with planetary gear sets (TEj) defining ratios and each associated with a clutch (EMj) comprising a piston (Pj) exerting pressure on discs (DEj), and - ii) a prime mover (MT) supplying engine torque to said gearbox (BV), - iii) control means (MC) which, when a change from an outgoing gear to an incoming gear has been decided, determine a pressure to be exerted by the piston (Pj) associated with the incoming gear in order to fully transmit the engine torque, characterized in that the control means (MC) control: - either the engine torque at a torque setpoint value and the pressure at an optimum pressure to fully transmit the torque setpoint when an oil temperature in the gearbox (BV) is lower than a first chosen threshold and that a number of cumulative uses of the clutch (EMj) containing this piston (Pj) since the commissioning of the vehicle is less than a second chosen threshold, - either the engine torque at a reduced torque setpoint value and the pressure at a reduced pressure to fully transmit the reduced torque setpoint when the oil temperature is higher than the first chosen threshold or when the number of uses is higher than the second threshold chosen, the reduced torque setpoint value being equal to the torque setpoint value less a determined value and the reduced pressure being lower than the optimum pressure.
An electronic device comprising: a sensor including a light emitter and a light receiver , wherein the light emitter includes a light source emitting infrared light, and the light receiver includes a plurality of photodiodes ; and a processor , wherein the processor is configured to: measure infrared light reflected by a skin surface of a user by using the light receiver, identify that a predetermined condition indicating that the sensor is disposed parallel to the skin surface is satisfied by determining whether amounts of the measured infrared light received through the respective photodiodes are at least partially symmetrical or not, and detect biometric information of the user if the predetermined condition indicating that the sensor is disposed parallel to the skin surface is satisfied. a sensor including a light emitter and a light receiver , wherein the light emitter includes a light source emitting infrared light, and the light receiver includes a plurality of photodiodes ; and a processor , wherein the processor is configured to: measure infrared light reflected by a skin surface of a user by using the light receiver, identify that a predetermined condition indicating that the sensor is disposed parallel to the skin surface is satisfied by determining whether amounts of the measured infrared light received through the respective photodiodes are at least partially symmetrical or not, and detect biometric information of the user if the predetermined condition indicating that the sensor is disposed parallel to the skin surface is satisfied. measure infrared light reflected by a skin surface of a user by using the light receiver, identify that a predetermined condition indicating that the sensor is disposed parallel to the skin surface is satisfied by determining whether amounts of the measured infrared light received through the respective photodiodes are at least partially symmetrical or not, and detect biometric information of the user if the predetermined condition indicating that the sensor is disposed parallel to the skin surface is satisfied.