mhurhangee/patent-ind-claim-en huggingface dataset:
Method for operating a rear laser lamp installed in a motor vehicle , which comprises a laser source emitting laser light and an optical unit connected downstream thereof and which irradiates a light distribution producing a laser pattern on a substrate travelled on by the motor vehicle , wherein, as a function of driving situation data describing cornering (II, III) of the motor vehicle , by means of driving dynamics data of a driving dynamics device of the motor vehicle and/or environment data of an environmental sensing device of the motor vehicle , which describe the course of the lane, at least one display parameter which specifies a position of the laser pattern that is to be generated is determined, after which at least one irradiation parameter of the light distribution is changed as a function of the display parameter, wherein as irradiation parameter a horizontal irradiation angle of the light distribution is changed, in such a way that the lateral position of the laser pattern with respect to the longitudinal axis of the vehicle is adjusted, wherein the at least one display parameter specifies the position in such a way that the laser pattern is displayed on a lane currently being travelled on by the motor vehicle , wherein, for changing the at least one irradiation parameter of the light distribution , at least one deflector device that is arranged in the beam path of the laser light and/or that acts on the optical unit by twisting, pivoting and/or linear movement, in particular at least one micro-optoelectromechanical element and/or at least one acousto-optical modulator, is used, wherein the display parameter additionally specifies an orientation of the laser pattern in such a way that the laser pattern , which in a standard driving situation is generated in bar form, is displayed during cornering on the lane currently being travelled on by the vehicle, perpendicularly to a course of the lane .
Device for direction recognition in passages with a housing , a first PIR sensor and a second PIR sensor in the housing and with a viewing window in front of the PIR sensors which is transparent to infrared radiation, wherein the housing has a detection zone for reducing the detection range in each case between one of the PIR sensors and the viewing window of the PIR sensor , 4), characterised in that in each case a viewing window is in front of an associated PIR sensor and in that the detection zone is a slot-shaped tunnel in the housing , so that a viewing window and a slot-shaped tunnel are arranged in front of each PIR sensor , the slot-shaped tunnel having an IR-absorbing surface of the tunnel walls and extending with its tunnel walls adjacent to the respective viewing window towards the respective PIR sensor and limits IR radiation incident through the viewing window in such a way that the infrared radiation strikes the sensitive surface of the PIR sensor at a 90° angle with a tolerance deviation of up to +/- 20° and the reflection of laterally incident IR radiation within the housing is reduced.
Method for producing a plug-in connector for plug connection to an associated mating plug-in connector , wherein, in the method, a housing is produced in which a contact insert is to be accommodated, the contact insert forming a plug-in face for plug connection to the mating plug-in connector and having at least one electrical contact element for making electrical contact with at least one mating contact element of the mating plug-in connector , characterized in that a plurality of insert elements which are intended for use on the plug-in connector and are designed for providing different functionalities on the plug-in connector are provided, at least one insert element from the plurality of insert elements is selected, and the at least one selected insert element is connected to the housing during the production of the housing by the housing being produced by means of injection moulding, and, during the production of the housing , the at least one selected insert element being insert-moulded at least in certain sections in such a manner that the at least one selected insert element is connected in an integrally bonded manner to the housing .
Use of a variant Fc-region comprising the mutation Y436A for increasing the binding of a dimeric Fc-region polypeptide compriing a first polypeptide and a second polypeptide each comprising in N-terminal to C-terminal direction at least a portion of an immunoglobulin hinge region, which comprises one or more cysteine residues, an immunoglobulin CH2-domain and an immunoglobulin CH3-domain, wherein the first, the second or the first and the second polypeptide comprise the mutation Y436A (numbering according to the EU index) to protein A. a first polypeptide and a second polypeptide each comprising in N-terminal to C-terminal direction at least a portion of an immunoglobulin hinge region, which comprises one or more cysteine residues, an immunoglobulin CH2-domain and an immunoglobulin CH3-domain, wherein the first, the second or the first and the second polypeptide comprise the mutation Y436A (numbering according to the EU index) to protein A.
A lockable electronics cabinet , comprising a body and a door , said door being arranged to be opened in a sequence of motions, comprising, first, a linear motion perpendicular to the plane of the door and then, a rotational motion around a pivot axis, wherein said cabinet comprises a linear motion mechanism , said linear motion mechanism comprising a moving frame connected to said door , a stationary frame connected to a main part of said body , a first guiding track provided by one of said moving frame and said stationary frame, and a guiding arrangement provided by the other of said moving frame and said stationary frame, characterized by said first guiding track and said guiding arrangement thereby being movable with respect to each other in direction of said linear motion, said linear motion mechanism further comprising a driving member configured to drive said linear motion by running along a pre-determined path defined by the driving member engaging with the guiding arrangement while simultaneously engaging with said first guiding track , wherein, with a first location along said pre-determined path corresponding to a second location along said first guiding track such that said driving member , while running along said pre-determined path through said first location, engages with said first guiding track at said second location, a tangent direction of said first pre-determined path at said first location is different from a tangent direction of said first guiding track at said second location.
A humidifier for a test chamber, in particular a climate chamber, said humidifier comprising a container having a container interior for receiving a water bath , a heating device of a temperature-control system for controlling the temperature of the water bath, and a ventilation system for generating air bubbles in the water bath, a container opening being formed in the container above the water bath in order to connect the container interior to a test space of a test chamber, characterized in that the humidifier comprises a cooling device of the temperature-control system, the heating device and the cooling device each having a heat exchanger arranged in the water bath .
A combination comprising a first immune checkpoint inhibitor and an IRM compound for use in the treatment of a tumor; wherein the IRM compound is N-(4-{[4-amino-2-butyl-1 H -imidazo[4,5- c ]quinolin-1-yl]oxy}butyl)octadecanamide, or a pharmaceutically acceptable salt thereof, and wherein the immune checkpoint inhibitor compound is (i) a CTLA-4 receptor antibody or a fragment thereof or (ii) an anti-PD-L1 antibody or a fragment thereof.
A tube filter production device for producing a smoking article tube filter, the tube filter production device comprising: a tube filter exterior forming case into which one or more filter tows are to be introduced and from which a tubular rod (TF) formed from the one or more filter tows is to be discharged; a tube filter forming bar extending in an inner region of the tube filter exterior forming case in order to form a hollow of the tubular rod (TF); and a steam chamber having at least one steam nozzle in communication with the inner region of the tube filter exterior forming case and configured to supply steam to the one or more filter tows through the steam nozzle , wherein the tube filter forming bar has a duct extending in a longitudinal direction of the tube filter forming bar and a flavoring nozzle formed in a downstream end region of the tube filter forming bar to deliver a flavoring liquid or a moisturizing liquid supplied through the duct to the hollow of the tubular rod (TF), characterized in that the tube filter forming bar includes a forming bar body portion and a forming bar tip coupled to a downstream end of the forming bar body portion ; and a second duct that is in fluid communication with a first duct formed in the forming bar body portion and has a diameter smaller than or equal to a diameter of the first duct is formed in the forming bar tip . a tube filter exterior forming case into which one or more filter tows are to be introduced and from which a tubular rod (TF) formed from the one or more filter tows is to be discharged; a tube filter forming bar extending in an inner region of the tube filter exterior forming case in order to form a hollow of the tubular rod (TF); and a steam chamber having at least one steam nozzle in communication with the inner region of the tube filter exterior forming case and configured to supply steam to the one or more filter tows through the steam nozzle , characterized in that the tube filter forming bar includes a forming bar body portion and a forming bar tip coupled to a downstream end of the forming bar body portion ; and a second duct that is in fluid communication with a first duct formed in the forming bar body portion and has a diameter smaller than or equal to a diameter of the first duct is formed in the forming bar tip .
A solution of sacrosidase derived from Saccharomyces cerevisiae in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 IU/mL and a residual papain concentration of less than 10 ng/mL for use in a method to treat the symptoms of sucrase-isomaltase deficiency (SID) in a human patient, wherein a daily dose of the solution of about 2-10 mL per day does not induce an allergic reaction in the human patient, and wherein the primary structure of the sacrosidase is a 513 amino acid polypeptide that is glycosylated.
A method for operating a battery pack comprising a housing including an electromechanical interface for connecting to an electric tool, a stationary machine, a cleaning appliance, or a gardening tool, the method comprising the steps: - providing multiple different target settings relating to the battery pack , which are selectable by a user; - target-specific setting of at least one operating parameter of the battery pack by a battery management system , which is integrated into the housing of the battery pack , depending on which of the target settings is selected; characterized by the method step: - operating the battery pack by the battery management system , which controls and/or regulates the battery pack autonomously, according to the target-specifically set operating parameter. - providing multiple different target settings relating to the battery pack , which are selectable by a user; - target-specific setting of at least one operating parameter of the battery pack by a battery management system , which is integrated into the housing of the battery pack , depending on which of the target settings is selected; - operating the battery pack by the battery management system , which controls and/or regulates the battery pack autonomously, according to the target-specifically set operating parameter.
A pharmaceutical composition suitable for oral administration wherein the composition comprises spray-dried particles of a compound of Formula I or a pharmaceutically acceptable salt thereof 2-(1,5-dimethyl-3-phenyl-1H-pyrrol-2-yl)-N-(4-(4-(5-fluoropyrimidin-2-yl)piperazin-1-yl)phenyl)-2-oxoacetamide.
Axial ball stud for use in vehicle steering devices or vehicle suspensions, having a straight or curved metal rod, preferably made of steel or aluminium, a threaded section arranged at one end of the metal rod, and a joint ball (18, 18-2, 18-3, 18-4, 18-5, 18-6) arranged at the other end of the metal rod, wherein a kink region is provided between the threaded section and the end pin (22, 22-2, 22-3, 22-4, 22-5, 22-6), characterised in that the axial ball pin is designed in two parts, in that the joint ball (18, 18-2, 18-3, 18-4, 18-5, 18-6) has a longitudinal opening (20, 20-2, 20-3, 20-4, 20-5, 20-6) running at least to its centre, preferably through its centre, into which the metal rod with an end pin (22, 22-2, 22-3, 22-4, 22-5, 22-6) protrudes, wherein the joint ball (18, 18-2, 18-3, 18-4, 18-5, 18-6) and end pin (22, 22-2, 22-3, 22-4, 22-5, 22-6) are positively and/or non-positively connected to one another in this longitudinal opening (20, 20-2, 20-3, 20-4, 20-5, 20-6), wherein the end pin (22, 22-2, 22-3, 22-4, 22-5, 22-6) has a strength that is at least 100 N/mm 2 greater than an area of the metal rod that adjoins the end pin (22, 22-2, 22-3, 22-4, 22-5, 22-6) on the threaded section side.
A method for reconstructing an image of a subject while correcting for gradient nonlinearity effects using a magnetic resonance imaging ("MRI") system, the steps of the method comprising: (a) providing magnetic resonance data acquired from a subject using an MRI system; (b) providing an estimate of a gradient distortion field associated with the MRI system; (c) reconstructing at least one image of the subject from the magnetic resonance data while correcting for errors associated with a gradient nonlinearity by using an integrated image reconstruction and gradient nonlinearity correction technique which incorporates the estimate of the gradient distortion field into a magnetic resonance signal model to account for the errors associated with the gradient nonlinearity during image reconstruction, thereby simultaneously reconstructing the at least one image of the subject and correcting the at least one image for the errors associated with the gradient nonlinearity. (a) providing magnetic resonance data acquired from a subject using an MRI system; (b) providing an estimate of a gradient distortion field associated with the MRI system; (c) reconstructing at least one image of the subject from the magnetic resonance data while correcting for errors associated with a gradient nonlinearity by using an integrated image reconstruction and gradient nonlinearity correction technique which incorporates the estimate of the gradient distortion field into a magnetic resonance signal model to account for the errors associated with the gradient nonlinearity during image reconstruction, thereby simultaneously reconstructing the at least one image of the subject and correcting the at least one image for the errors associated with the gradient nonlinearity.
A device for positioning of a stent within coronary arteries, comprising a housing with a through hole for placing a coronary stent delivery system, said housing comprising a truncated front part with recesses for the operator's hand and a pressure surface , and a cylindrical rear part connected to the front part and provided with a circumferential thread in contact with a protrusion on a runner arranged inside the cylindrical rear part so as to be displaceable along guides inside the housing, characterized in that the pressure surface is on the outer lateral surface of the housing, the cylindrical rear part is connected to the front part rotatably relative to the front part and is displaceable also by means of a bushing connected to a gripping means provided with flaps with elastic members at the gripping point of the delivery system on the bushing side and with protrusions provided on the opposite side and arranged within a pressure roller comprising two halves and contacting a release means inner surface arranged inside the housing and comprising flaps in the forms of plates arranged at an angle to each other and to the pressure roller and fixedly connected to the release means having a pressure surface in the form of plates on an outer lateral surface of the truncated part of the housing.
A process for preparing a product that comprises a physical component and a Silica Documentation , the physical component including diatomite, wherein a crystalline silica content of the physical component by weight is greater as measured according to Traditional Methods than as measured according to an LH Method as described in the description, wherein Traditional Methods is x-ray diffraction analysis that treats opal-C as cristobalite when measuring and quantifying crystalline silica phases, the Silica Documentation disclosing the crystalline silica content present in the physical component as measured according to the LH Method, the process for preparing the product comprising: manufacturing the physical component of the product from a selected diatomite ore, optionally with a fluxing additive; analyzing the physical component of the product for the crystalline silica content using the LH Method to determine a cristobalite content, and preparing the Silica Documentation based on a result of the analyzing of the physical component of the product for the crystalline silica content using the LH Method to determine the cristobalite content. the physical component including diatomite, wherein a crystalline silica content of the physical component by weight is greater as measured according to Traditional Methods than as measured according to an LH Method as described in the description, wherein Traditional Methods is x-ray diffraction analysis that treats opal-C as cristobalite when measuring and quantifying crystalline silica phases, the Silica Documentation disclosing the crystalline silica content present in the physical component as measured according to the LH Method, the process for preparing the product comprising: manufacturing the physical component of the product from a selected diatomite ore, optionally with a fluxing additive; analyzing the physical component of the product for the crystalline silica content using the LH Method to determine a cristobalite content, and preparing the Silica Documentation based on a result of the analyzing of the physical component of the product for the crystalline silica content using the LH Method to determine the cristobalite content. manufacturing the physical component of the product from a selected diatomite ore, optionally with a fluxing additive; analyzing the physical component of the product for the crystalline silica content using the LH Method to determine a cristobalite content, and preparing the Silica Documentation based on a result of the analyzing of the physical component of the product for the crystalline silica content using the LH Method to determine the cristobalite content.
A compound of formula (I) wherein: R 1 is alkyl or alkyl-R 7 or -aryl-R 7 ; R 2 , R 3 , R 4 , R 5 are independently H, halo, -B(O-R 11 ) 2 , alkyl, alkoxyl, hydroxycarbonyl, -COOR 11 , -CO-NR 8 R 9 or aryl; R 6 is H or alkyl; or R 1 and R 6 are bound together to form a 5 or 6-member heterocycle; R 7 is hydroxyl, alkylhydroxyl, -NR 8 R 9 , -CO-X-R 10 , -CN, -CF 3 , aryl; R 8 and R 9 are independently H, alkyl or form together with the nitrogen atom a 3 to 6-member cyclic group; X is -O- or -NR 11 -; R 10 is H, alkyl or hydroxyalkyl; R 11 is H or alkyl; or pharmaceutically acceptable salts thereof. R 1 is alkyl or alkyl-R 7 or -aryl-R 7 ; R 2 , R 3 , R 4 , R 5 are independently H, halo, -B(O-R 11 ) 2 , alkyl, alkoxyl, hydroxycarbonyl, -COOR 11 , -CO-NR 8 R 9 or aryl; R 6 is H or alkyl; or R 1 and R 6 are bound together to form a 5 or 6-member heterocycle; R 7 is hydroxyl, alkylhydroxyl, -NR 8 R 9 , -CO-X-R 10 , -CN, -CF 3 , aryl; R 8 and R 9 are independently H, alkyl or form together with the nitrogen atom a 3 to 6-member cyclic group; X is -O- or -NR 11 -; R 10 is H, alkyl or hydroxyalkyl; R 11 is H or alkyl; or pharmaceutically acceptable salts thereof.
A negative-pressure dressing for use on a tissue site, comprising: a manifold having a first surface and a second surface ; and a cover for disposing over the manifold , wherein the cover comprises: an interior surface that, when disposed over the manifold at least a portion of the interior surface faces towards the second surface of the manifold , an exterior surface , a port configured for introduction of negative pressure through the cover , and a plurality of channels on at least a portion of the interior surface and sized for capillary action. a manifold having a first surface and a second surface ; and a cover for disposing over the manifold , wherein the cover comprises: an interior surface that, when disposed over the manifold at least a portion of the interior surface faces towards the second surface of the manifold , an exterior surface , a port configured for introduction of negative pressure through the cover , and a plurality of channels on at least a portion of the interior surface and sized for capillary action. an interior surface that, when disposed over the manifold at least a portion of the interior surface faces towards the second surface of the manifold , an exterior surface , a port configured for introduction of negative pressure through the cover , and a plurality of channels on at least a portion of the interior surface and sized for capillary action.
An integrated sample acquisition and sample stabilization device comprising: (i) a sample acquisition component comprising one or more piercing elements; (ii) more than one paper stabilization matrix, wherein the more than one paper stabilization matrices are stacked, and wherein the more than one paper stabilization matrices do not contact each other; and (iii) a channel configured to allow a biological sample to move from an opening in the sample acquisition component through the channel onto the more than one paper stabilization matrices, wherein the more than one paper stabilization matrices are configured to stabilize one or more biological components. (i) a sample acquisition component comprising one or more piercing elements; (ii) more than one paper stabilization matrix, wherein the more than one paper stabilization matrices are stacked, and wherein the more than one paper stabilization matrices do not contact each other; and (iii) a channel configured to allow a biological sample to move from an opening in the sample acquisition component through the channel onto the more than one paper stabilization matrices, wherein the more than one paper stabilization matrices are configured to stabilize one or more biological components.