A polyurethane composition (P) comprising: a) from 80 to 99.9% by weight, based on the total weight of the polyurethane composition (P), of at least one polyurethane component (A); b) from 0.05 to 1.5% by weight (500 to 15,000 ppm), based on the total weight of the polyurethane composition (P), of at least one complexing agent (B); c) from 0.005 to 5% by weight (50 to 50,000 ppm), based on the total weight of the polyurethane composition (P), of at least one organic antimicrobially active component (C) comprising at least one nitrogen atom; d) optionally up to 15% by weight, based on the total weight of the polyurethane composition (P), of one or more polymers (D) different from the at least one polyurethane component (A) and e) optionally up to 5% by weight, based on the total weight of the polyurethane composition (P), of one or more additives (E); wherein the at least one complexing agent (B) is selected from the group consisting of organic compounds having at least two functional moieties, of which at least one functional moiety is a carboxylic acid moiety or a salt thereof; and wherein the at least one organic antimicrobially active component (C) comprising at least one nitrogen atom is selected from the group consisting of quaternary ammonium salts having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, primary, secondary or tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, N-oxides of tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, tertiary amines having a C 8 -C 30 hydrocarbon moiety and two aminoalkyl moieties attached to the tertiary nitrogen atom, and polymers having repeating units comprising quaternary ammonium moieties or amine moieties. a) from 80 to 99.9% by weight, based on the total weight of the polyurethane composition (P), of at least one polyurethane component (A); b) from 0.05 to 1.5% by weight (500 to 15,000 ppm), based on the total weight of the polyurethane composition (P), of at least one complexing agent (B); c) from 0.005 to 5% by weight (50 to 50,000 ppm), based on the total weight of the polyurethane composition (P), of at least one organic antimicrobially active component (C) comprising at least one nitrogen atom; d) optionally up to 15% by weight, based on the total weight of the polyurethane composition (P), of one or more polymers (D) different from the at least one polyurethane component (A) and e) optionally up to 5% by weight, based on the total weight of the polyurethane composition (P), of one or more additives (E); wherein the at least one complexing agent (B) is selected from the group consisting of organic compounds having at least two functional moieties, of which at least one functional moiety is a carboxylic acid moiety or a salt thereof; and wherein the at least one organic antimicrobially active component (C) comprising at least one nitrogen atom is selected from the group consisting of quaternary ammonium salts having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, primary, secondary or tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, N-oxides of tertiary amines having at least one C 8 -C 30 hydrocarbon moiety attached to the nitrogen atom, tertiary amines having a C 8 -C 30 hydrocarbon moiety and two aminoalkyl moieties attached to the tertiary nitrogen atom, and polymers having repeating units comprising quaternary ammonium moieties or amine moieties. <EOS>