mhurhangee/patent-ind-claim-en huggingface dataset:
A compound according to Formula I: wherein: Ring A is aryl or heterocyclyl; n is 0, 1, 2, 3 or 4; R 1 is independently selected from: (C 1 -C 4 )alkyl, (C 3 -C 6 )cycloalkyl, heterocyclyl, CF 3 , CHF 2 , CN, halo, said alkyl, cycloalkyl and heterocyclyl optionally substituted with halo, OH, CH 3 , and OCH 3 ; R 2 is H and R 3 is independently selected from: (C 1 -C 6 )alkyl, (C 3 -C 8 )cycloalkyl, and heterocyclyl each optionally substituted with one or more halo, OH, N(R b ) 2 , or morpholinyl, or R 2 and R 3 can be taken together with the nitrogen to which they are attached to form a heterocyclyl, said heterocyclyl optionally substituted with one or more substituents selected from R a ; R a is independently selected from (C 1 -C 4 )alkyl, (C 3 -C 6 )cycloalkyl, CF 3 , CHF 2 , OH, halo and NH 2 , said alkyl optionally substituted with (C 3 -C 6 )cycloalkyl and CF 3 ; and R b is independently selected from H and (C 1 -C 4 )alkyl; or a pharmaceutically acceptable salt thereof. Ring A is aryl or heterocyclyl; n is 0, 1, 2, 3 or 4; R 1 is independently selected from: (C 1 -C 4 )alkyl, (C 3 -C 6 )cycloalkyl, heterocyclyl, CF 3 , CHF 2 , CN, halo, said alkyl, cycloalkyl and heterocyclyl optionally substituted with halo, OH, CH 3 , and OCH 3 ; R 2 is H and R 3 is independently selected from: (C 1 -C 6 )alkyl, (C 3 -C 8 )cycloalkyl, and heterocyclyl each optionally substituted with one or more halo, OH, N(R b ) 2 , or morpholinyl, or R 2 and R 3 can be taken together with the nitrogen to which they are attached to form a heterocyclyl, said heterocyclyl optionally substituted with one or more substituents selected from R a ; R a is independently selected from (C 1 -C 4 )alkyl, (C 3 -C 6 )cycloalkyl, CF 3 , CHF 2 , OH, halo and NH 2 , said alkyl optionally substituted with (C 3 -C 6 )cycloalkyl and CF 3 ; and R b is independently selected from H and (C 1 -C 4 )alkyl;
A laser generator comprising: a laser source producing a beam of light; and an optical assembly downstream of the laser source, wherein the optical assembly receives the beam of light, wherein the optical assembly comprises: a waveplate receiving the beam of light; a thin film polarizer downstream of the waveplate and receiving the beam of light and reflecting a first portion of the beam of light and allowing a second portion of the beam of light to pass therethrough characterised in that the optical assembly further comprises: a beam dump receiving the first portion of the beam of light; a beam expander downstream of the waveplate and receiving the second portion of the beam of light; a diffuser downstream of the beam expander and receiving the second portion of the beam of light; and a mixing fiber downstream of the diffuser and receiving the second portion of the beam of light, wherein the mixing fiber emits the second portion of the beam of light. a laser source producing a beam of light; and an optical assembly downstream of the laser source, wherein the optical assembly receives the beam of light, wherein the optical assembly comprises: a waveplate receiving the beam of light; a thin film polarizer downstream of the waveplate and receiving the beam of light and reflecting a first portion of the beam of light and allowing a second portion of the beam of light to pass therethrough a waveplate receiving the beam of light; a thin film polarizer downstream of the waveplate and receiving the beam of light and reflecting a first portion of the beam of light and allowing a second portion of the beam of light to pass therethrough characterised in that the optical assembly further comprises: a beam dump receiving the first portion of the beam of light; a beam expander downstream of the waveplate and receiving the second portion of the beam of light; a diffuser downstream of the beam expander and receiving the second portion of the beam of light; and a mixing fiber downstream of the diffuser and receiving the second portion of the beam of light, wherein the mixing fiber emits the second portion of the beam of light. a beam dump receiving the first portion of the beam of light; a beam expander downstream of the waveplate and receiving the second portion of the beam of light; a diffuser downstream of the beam expander and receiving the second portion of the beam of light; and a mixing fiber downstream of the diffuser and receiving the second portion of the beam of light, wherein the mixing fiber emits the second portion of the beam of light.
Method for the preparation of microporous organic POF (Porous Organic Framework) membranes, containing at least two different organic compounds, which contain aromatic modules, wherein at least one of the organic compounds comprises at least two functional groups and at least one of the other organic compounds comprises at least three functional groups, with the following method steps: a) preparing a sacrificial coating with a multiplicity of identical functional groups b) applying a first layer of an organic compound by reaction with the functional groups of the sacrificial coating c) applying of a first layer of a second organic compound by reaction with at least one of the functional groups of the organic compounds of the first layer d) dissolving the sacrificial coating e) removing of the POF membrane wherein at least one of the functional groups of a layer or of the sacrificial coating reacts with at least one of the functional groups of the subsequent layer, and the functional groups of the sequential layers are complementary and/or are protected by protective groups, wherein more than two different organic compounds are used in order to produce more than two different layers, wherein the sacrificial coating consists of an MOF (Metal-Organic Framework) or SURMOF (Surface Anchored Metal-Organic Framework) material, wherein the POF membrane is free-standing and comprises a homogeneous continuous coating thickness of at least 0.3 nm and a pore size of 0.01 - 2 nm. a) preparing a sacrificial coating with a multiplicity of identical functional groups b) applying a first layer of an organic compound by reaction with the functional groups of the sacrificial coating c) applying of a first layer of a second organic compound by reaction with at least one of the functional groups of the organic compounds of the first layer d) dissolving the sacrificial coating e) removing of the POF membrane wherein at least one of the functional groups of a layer or of the sacrificial coating reacts with at least one of the functional groups of the subsequent layer, and the functional groups of the sequential layers are complementary and/or are protected by protective groups, wherein more than two different organic compounds are used in order to produce more than two different layers, wherein the sacrificial coating consists of an MOF (Metal-Organic Framework) or SURMOF (Surface Anchored Metal-Organic Framework) material, wherein the POF membrane is free-standing and comprises a homogeneous continuous coating thickness of at least 0.3 nm and a pore size of 0.01 - 2 nm.
An apparatus for providing power to a multipole in a mass spectrometer , the apparatus comprising: a first resonant LC circuit ; at least one inductor for forming a second resonant LC circuit with said multipole , said second resonant LC circuit connected in cascade with said first resonant LC circuit , when said at least one inductor is connected to said multipole ; an RF power source for providing an RF signal; and a step-up transformer connected in parallel to said RF power source on a primary side and said first resonant LC circuit on a secondary side, said step-up transformer providing voltage gain (Vg) for said RF signal thereby reducing the loaded Q of said resonant LC circuits. a first resonant LC circuit ; at least one inductor for forming a second resonant LC circuit with said multipole , said second resonant LC circuit connected in cascade with said first resonant LC circuit , when said at least one inductor is connected to said multipole ; an RF power source for providing an RF signal; and a step-up transformer connected in parallel to said RF power source on a primary side and said first resonant LC circuit on a secondary side, said step-up transformer providing voltage gain (Vg) for said RF signal thereby reducing the loaded Q of said resonant LC circuits.
A pool cleaner, comprising: a canister body including an inner chamber within inner walls of the canister body; a filtering medium assembly disposed within the inner chamber of the canister body ; and a cyclone block disposed within the inner chamber of the canister body and at least partially surrounded by the filtering medium assembly , the cyclone block including a plurality of cyclone containers ; wherein a first cyclonic flow is generated between the inner walls of the canister body and the filtering medium assembly ; and wherein a second cyclonic flow is generated within each of the plurality of cyclone containers ; and characterized by a fine debris container disposed within the inner chamber of the canister body , the fine debris container including a dish and a central radial extension protruding from a bottom surface of the fine debris container . a canister body including an inner chamber within inner walls of the canister body; a filtering medium assembly disposed within the inner chamber of the canister body ; and a cyclone block disposed within the inner chamber of the canister body and at least partially surrounded by the filtering medium assembly , the cyclone block including a plurality of cyclone containers ; wherein a first cyclonic flow is generated between the inner walls of the canister body and the filtering medium assembly ; and wherein a second cyclonic flow is generated within each of the plurality of cyclone containers ; and characterized by a fine debris container disposed within the inner chamber of the canister body , the fine debris container including a dish and a central radial extension protruding from a bottom surface of the fine debris container . wherein a first cyclonic flow is generated between the inner walls of the canister body and the filtering medium assembly ; and wherein a second cyclonic flow is generated within each of the plurality of cyclone containers ; and characterized by a fine debris container disposed within the inner chamber of the canister body , the fine debris container including a dish and a central radial extension protruding from a bottom surface of the fine debris container .
An anti-free-flow valve comprising: a tube extending from a first end of the tube to a second end of the tube, the tube defining a hollow cavity, and a membrane attached to an interior surface of the tube and extending across the hollow cavity to obstruct fluid flow through the hollow cavity, the membrane spaced apart from the first and second ends of the tube, wherein the membrane defines a slit therethrough that is configured to transition from a closed state that restricts fluid flow to an open state that permits fluid flow through the slit responsive to compression or expansion of the tube proximate to the membrane , characterised in that the membrane has a concave curved shape that extends to a center point of the membrane and the slit extends through the center point, the membrane oriented relative to a direction of the fluid flow through the tube such that the concave curved shape funnels the fluid flow towards the slit . a tube extending from a first end of the tube to a second end of the tube, the tube defining a hollow cavity, and a membrane attached to an interior surface of the tube and extending across the hollow cavity to obstruct fluid flow through the hollow cavity, the membrane spaced apart from the first and second ends of the tube, wherein the membrane defines a slit therethrough that is configured to transition from a closed state that restricts fluid flow to an open state that permits fluid flow through the slit responsive to compression or expansion of the tube proximate to the membrane , characterised in that the membrane has a concave curved shape that extends to a center point of the membrane and the slit extends through the center point, the membrane oriented relative to a direction of the fluid flow through the tube such that the concave curved shape funnels the fluid flow towards the slit .
A liquid dispenser, comprising: a container configured to store liquid and having an upper opening; a lid provided on the container to cover the upper opening, the lid and the container being configured to insulate the liquid stored in the container from a temperature outside the container ; a pump configured to pump liquid to an upper surface of the lid (300 and 400); and a base to support the container and having a thermoelectric assembly to change a temperature of the liquid in the container , characterised in that the thermoelectric assembly is at least partially exposed to the liquid in the container via openings in the base and the container . a container configured to store liquid and having an upper opening; a lid provided on the container to cover the upper opening, the lid and the container being configured to insulate the liquid stored in the container from a temperature outside the container ; a pump configured to pump liquid to an upper surface of the lid (300 and 400); and a base to support the container and having a thermoelectric assembly to change a temperature of the liquid in the container , characterised in that the thermoelectric assembly is at least partially exposed to the liquid in the container via openings in the base and the container .
A vessel for laying cables on or in a sea bed, comprising a device for reeling in a cable from a source and temporarily storing the cable, the device comprising - a first; and a second storage unit, each comprising a cylindrical body for arranging the cable, wherein a cylinder longitudinal axis of the first storage unit does not coincide with a rotation axis of the second storage unit; - support means for carrying the cable from the source to cable seizing means of the second storage unit and further to the first storage unit; wherein - the first storage unit is configured to reel in the cable from the source; - the second storage unit is rotatable around the rotation axis parallel to the cylinder longitudinal axis of the second storage unit in a reeling direction, in which the cable is reeled in from the source; and - the storage units are arranged such that the second storage unit when rotating in the reeling direction simultaneously reels in a part of the cable originating from the source and another part of the cable originating from the first storage unit, wherein further - the cable seizing means of the second storage unit comprise a centrally of the second storage unit disposed cylindrical core and are configured to seize the cable such that a rotation of the second storage unit winds the cable around the centrally disposed core from opposite sides of the core, and - the centrally disposed core of the cable seizing means is provided with a passage for the cable extending in a cross-direction of the core . - a first; and a second storage unit, each comprising a cylindrical body for arranging the cable, wherein a cylinder longitudinal axis of the first storage unit does not coincide with a rotation axis of the second storage unit; - support means for carrying the cable from the source to cable seizing means of the second storage unit and further to the first storage unit; - the first storage unit is configured to reel in the cable from the source; - the second storage unit is rotatable around the rotation axis parallel to the cylinder longitudinal axis of the second storage unit in a reeling direction, in which the cable is reeled in from the source; and - the storage units are arranged such that the second storage unit when rotating in the reeling direction simultaneously reels in a part of the cable originating from the source and another part of the cable originating from the first storage unit, wherein further - the cable seizing means of the second storage unit comprise a centrally of the second storage unit disposed cylindrical core and are configured to seize the cable such that a rotation of the second storage unit winds the cable around the centrally disposed core from opposite sides of the core, and - the centrally disposed core of the cable seizing means is provided with a passage for the cable extending in a cross-direction of the core .
A method of two-stage combustion integrating in situ oxygen generation, the method characterized by the steps of: oxidizing, using an air reactor, a reduced oxygen carrier stream to form an oxidized oxygen carrier stream; separating, in a primary separator, an oxygen carrier and oxygen-depleted air from the oxidized oxygen carrier stream; dividing the oxidized oxygen carrier stream into a first stream fed to a primary fuel reactor and a second stream fed to an oxygen generation system; producing, in the oxygen generation system, gaseous oxygen; combusting, using the primary fuel reactor, fuel in the presence of the oxygen carrier; combusting, using a secondary fuel reactor, at least one of an additional fuel supply and an unburned fuel exiting the primary fuel reactor in the presence of the gaseous oxygen; wherein combusting fuel in the presence of the oxygen carrier forms the reduced oxygen carrier stream, which is conveyed to the air reactor for recycling. oxidizing, using an air reactor, a reduced oxygen carrier stream to form an oxidized oxygen carrier stream; separating, in a primary separator, an oxygen carrier and oxygen-depleted air from the oxidized oxygen carrier stream; dividing the oxidized oxygen carrier stream into a first stream fed to a primary fuel reactor and a second stream fed to an oxygen generation system; producing, in the oxygen generation system, gaseous oxygen; combusting, using the primary fuel reactor, fuel in the presence of the oxygen carrier; combusting, using a secondary fuel reactor, at least one of an additional fuel supply and an unburned fuel exiting the primary fuel reactor in the presence of the gaseous oxygen; wherein combusting fuel in the presence of the oxygen carrier forms the reduced oxygen carrier stream, which is conveyed to the air reactor for recycling.
An infusion set, comprising: a set , comprising a skin contacting surface and a catheter extending from a lower surface thereof; and a flexible ring , wherein the flexible ring is configured to expand to a first diameter to allow placement over said set , and contract to a second diameter to securely circumscribe an outer diameter of said set ; characterized in that the infusion set further comprises: a tubing length secured to said flexible ring ; and a fitting or spike , disposed at an end of said tubing length and extending into said flexible ring , said fitting or spike configured to sealably mate with an opening of said set to permit communication of a medicament therebetween. a set , comprising a skin contacting surface and a catheter extending from a lower surface thereof; and a flexible ring , wherein the flexible ring is configured to expand to a first diameter to allow placement over said set , and contract to a second diameter to securely circumscribe an outer diameter of said set ; characterized in that the infusion set further comprises: a tubing length secured to said flexible ring ; and a fitting or spike , disposed at an end of said tubing length and extending into said flexible ring , said fitting or spike configured to sealably mate with an opening of said set to permit communication of a medicament therebetween. a tubing length secured to said flexible ring ; and a fitting or spike , disposed at an end of said tubing length and extending into said flexible ring , said fitting or spike configured to sealably mate with an opening of said set to permit communication of a medicament therebetween.
A method (1400; 1500; 1600) of wireless communication at a base station comprising: determining (1405; 1505; 1605) a Doppler metric associated with a wireless channel and a user equipment, UE; selecting (1410; 1510; 1610) a first reference signal density configuration based at least in part on the Doppler metric; selecting, from a plurality of wireless channel estimation techniques and based at least in part on the Doppler metric, a wireless channel estimation technique for communication with the UE; wherein selecting the wireless channel estimation technique comprises: (i) selecting a causal wireless channel estimation technique if the Doppler metric is below a first threshold, and (ii) selecting a non-causal wireless channel estimation technique if the Doppler metric is above a second threshold; and transmitting to the UE an indication of the first reference signal density configuration and a further indication to communicate with the base station using the selected wireless channel estimation technique. determining (1405; 1505; 1605) a Doppler metric associated with a wireless channel and a user equipment, UE; selecting (1410; 1510; 1610) a first reference signal density configuration based at least in part on the Doppler metric; selecting, from a plurality of wireless channel estimation techniques and based at least in part on the Doppler metric, a wireless channel estimation technique for communication with the UE; wherein selecting the wireless channel estimation technique comprises: (i) selecting a causal wireless channel estimation technique if the Doppler metric is below a first threshold, and (ii) selecting a non-causal wireless channel estimation technique if the Doppler metric is above a second threshold; and (i) selecting a causal wireless channel estimation technique if the Doppler metric is below a first threshold, and (ii) selecting a non-causal wireless channel estimation technique if the Doppler metric is above a second threshold; transmitting to the UE an indication of the first reference signal density configuration and a further indication to communicate with the base station using the selected wireless channel estimation technique.
A peptide homodimer comprising: (a) at least one IgG1 Fc domain comprising the point mutations S267E, H268F, and S324T and further comprising (i) the point mutation N297A; (ii) the point mutation G236R; or (iii) the point mutations G236R and E233P; and (b) at least one multimerization domain capable of multimerizing the peptide homodimer; wherein the peptide homodimer exhibits preferential binding to complement relative to FcγRI, FcγRIIa, FcγRIIb and/or FcγRIII. (a) at least one IgG1 Fc domain comprising the point mutations S267E, H268F, and S324T and further comprising (i) the point mutation N297A; (ii) the point mutation G236R; or (iii) the point mutations G236R and E233P; and (i) the point mutation N297A; (ii) the point mutation G236R; or (iii) the point mutations G236R and E233P; and (b) at least one multimerization domain capable of multimerizing the peptide homodimer;