mhurhangee/patent-ind-claim-en huggingface dataset:
A temperature difference power generation apparatus comprising: a thermoelectric conversion element configured to convert thermal energy into electric energy based on a temperature difference; radiation fins which are thermally connected to a low-temperature side of the thermoelectric conversion element and contactable to outside air; a pipe which is thermally connected to a high-temperature side of the thermoelectric conversion element and through which a high-temperature fluid at a higher temperature than the outside air is flowable; a plurality of first heat pipes which thermally connect the radiation fins and the low-temperature side of the thermoelectric conversion element to each other; and a base plate , wherein the radiation fins are supported by one end parts of the plurality of first heat pipes , wherein the other end parts of the plurality of first heat pipes are thermally connected to the low temperature side of the thermoelectric conversion element through the base plate , wherein the plurality of first heat pipes are installed in the base plate , and wherein the plurality of first heat pipes extend from side edge faces of both sides of the base plate in a width direction to both sides thereof in the width direction to support the radiation fins . a thermoelectric conversion element configured to convert thermal energy into electric energy based on a temperature difference; radiation fins which are thermally connected to a low-temperature side of the thermoelectric conversion element and contactable to outside air; a pipe which is thermally connected to a high-temperature side of the thermoelectric conversion element and through which a high-temperature fluid at a higher temperature than the outside air is flowable; a plurality of first heat pipes which thermally connect the radiation fins and the low-temperature side of the thermoelectric conversion element to each other; and a base plate , wherein the radiation fins are supported by one end parts of the plurality of first heat pipes , wherein the other end parts of the plurality of first heat pipes are thermally connected to the low temperature side of the thermoelectric conversion element through the base plate , wherein the plurality of first heat pipes are installed in the base plate , and wherein the plurality of first heat pipes extend from side edge faces of both sides of the base plate in a width direction to both sides thereof in the width direction to support the radiation fins .
An integrated circuit comprising: a magnetic tunnel junction (MTJ) comprising a fixed magnetic layer ; a first insulator layer formed over the fixed magnetic layer ; and a free magnetic layer formed over the first insulator layer ; a second insulator layer formed over the free magnetic layer ; an electrically conductive hardmask layer formed over the second insulator layer , wherein the hardmask layer has a width/diameter that is less than a width/diameter of the free magnetic layer ; a first dielectric spacer formed over the second insulator layer and covering sidewalls of the hardmask layer ; characterised by a second dielectric spacer formed over the fixed magnetic layer and covering sidewalls of the free magnetic layer . a magnetic tunnel junction (MTJ) comprising a fixed magnetic layer ; a first insulator layer formed over the fixed magnetic layer ; and a free magnetic layer formed over the first insulator layer ; a second insulator layer formed over the free magnetic layer ; an electrically conductive hardmask layer formed over the second insulator layer , wherein the hardmask layer has a width/diameter that is less than a width/diameter of the free magnetic layer ; a first dielectric spacer formed over the second insulator layer and covering sidewalls of the hardmask layer ; characterised by a second dielectric spacer formed over the fixed magnetic layer and covering sidewalls of the free magnetic layer .
An air brake control unit , comprising: a first electronic brake valve connector for receiving a first braking command signal from a first electronic brake valve of a first locomotive (A); a first electro-pneumatic control unit for operating a braking system of a train in response to the first braking command signal received from the first electronic brake valve; a relay for selectively connecting and disconnecting a power source of the first locomotive to the air brake control unit; and a first inter-unit connector interconnected to the power source and the first electronic brake valve and configured to establish a power supply connection between the first electronic brake valve and a second air brake control unit of a second locomotive (B) as well as between a second electronic brake valve of the second locomotive and the air brake control unit. a first electronic brake valve connector for receiving a first braking command signal from a first electronic brake valve of a first locomotive (A); a first electro-pneumatic control unit for operating a braking system of a train in response to the first braking command signal received from the first electronic brake valve; a relay for selectively connecting and disconnecting a power source of the first locomotive to the air brake control unit; and a first inter-unit connector interconnected to the power source and the first electronic brake valve and configured to establish a power supply connection between the first electronic brake valve and a second air brake control unit of a second locomotive (B) as well as between a second electronic brake valve of the second locomotive and the air brake control unit.
A catheter fixation device comprising: a body ; a catheter having a proximal portion and a distal portion that passes through an opening in said body ; and an anti-pull-out lock mechanism comprising an arcuate channel bounded by a pair of arcuate walls extending from a floor of said body , wherein a coiled portion of said catheter is constrained to move between said arcuate walls during movement of said proximal portion and said distal portion remains substantially in place; wherein said opening is positioned off-center of a floor of said body , and said anti-pull-out lock mechanism comprises one or more roof members that prevent vertical pull-out of said catheter with respect to said floor, and wherein some of said roof members extend arcuately inwards of one of said walls , while others of said roof members overlie near another one of said walls at several discrete positions. a body ; a catheter having a proximal portion and a distal portion that passes through an opening in said body ; and an anti-pull-out lock mechanism comprising an arcuate channel bounded by a pair of arcuate walls extending from a floor of said body , wherein a coiled portion of said catheter is constrained to move between said arcuate walls during movement of said proximal portion and said distal portion remains substantially in place; wherein said opening is positioned off-center of a floor of said body , and said anti-pull-out lock mechanism comprises one or more roof members that prevent vertical pull-out of said catheter with respect to said floor, and wherein some of said roof members extend arcuately inwards of one of said walls , while others of said roof members overlie near another one of said walls at several discrete positions.
An apparatus for carrying cargo, the apparatus being mountable in a subfloor region of an aircraft , comprising: a first bracket is adapted to be rigidly attached to a first structural component of the aircraft; a second bracket is adapted to be rigidly attached to a second structural component of the aircraft ; a cargo hook ; and a cargo sling beam that has a longitudinal axis in a longitudinal direction and first and second ends in the longitudinal direction, wherein the cargo sling beam has a tubular shape at the first and second ends and a constriction region at a predetermined location between the first and second ends that is narrower than the first and second ends, and wherein the cargo sling beam comprises: a suspension device in the constriction region that receives the cargo hook , and first and second attachments connect the first and second ends removably and at least partially pivotably around the longitudinal axis with the first and second brackets , respectively; wherein the suspension device further comprises a bolt that connects an attach point of the cargo hook with the cargo sling beam ; and a bolt bearing between the bolt and the attach point , characterized in that the bolt bearing has a section thinning on at least one side, the bolt bearing being adapted to ensure a turnout of the cargo hook during a crash of the aircraft .
A Tumor Micro-Environment (TME) responsive expression vector comprising: a nucleic acid sequence encoding a chimeric antigen receptor (CAR) operably linked to a synthetic promoter, said promoter comprising two or more different TME dependent promoter response elements (PRE), wherein said at least two PRE's are an interferon-gamma-(IFN-γ) PRE and an NEκB PRE, and wherein the IFN-γ promoter response element comprises the nucleic acid sequence set forth in SEQ ID NO: 1, and wherein the NEκB PRE comprises the nucleic acid sequence set forth in SEQ ID NO: 2 ("K"); wherein the TME responsive expression vector is so constructed that a) the presence of IFN-γ and TNFα in the TME, when binding to interferon-gamma-(IFN-γ) PRE and NEκB PRE, induces a higher expression level of CAR than when only IFN-γ or TNFα are present in the TME, and b) minimal or low expression of CAR occurs in the absence of IFN-γ and TNFα, so that the CAR is upregulated and directing activities against the tumor while sparing normal tissue. a nucleic acid sequence encoding a chimeric antigen receptor (CAR) operably linked to a synthetic promoter, said promoter comprising two or more different TME dependent promoter response elements (PRE), wherein said at least two PRE's are an interferon-gamma-(IFN-γ) PRE and an NEκB PRE, and wherein the IFN-γ promoter response element comprises the nucleic acid sequence set forth in SEQ ID NO: 1, and wherein the NEκB PRE comprises the nucleic acid sequence set forth in SEQ ID NO: 2 ("K"); wherein the TME responsive expression vector is so constructed that a) the presence of IFN-γ and TNFα in the TME, when binding to interferon-gamma-(IFN-γ) PRE and NEκB PRE, induces a higher expression level of CAR than when only IFN-γ or TNFα are present in the TME, and b) minimal or low expression of CAR occurs in the absence of IFN-γ and TNFα, a) the presence of IFN-γ and TNFα in the TME, when binding to interferon-gamma-(IFN-γ) PRE and NEκB PRE, induces a higher expression level of CAR than when only IFN-γ or TNFα are present in the TME, and b) minimal or low expression of CAR occurs in the absence of IFN-γ and TNFα,
A temperature sensor , comprising: a coil element serving as a part of a coil of an electric apparatus, the coil element having a rectangular cross-section; an element main body that includes a thermosensitive body detecting heat of the coil element , and paired electric wires connected to the thermosensitive body ; a housing that includes an electric insulating resin material, and is configured to house and hold the coil element , the element main body and the paired electric wires ; and a covering body that is configured to cover the element main body and the paired electric wires , the temperature sensor being characterized in that the housing includes, at a position corresponding to the thermosensitive body , a view window allowing for visual confirmation of the thermosensitive body from outside. a coil element serving as a part of a coil of an electric apparatus, the coil element having a rectangular cross-section; an element main body that includes a thermosensitive body detecting heat of the coil element , and paired electric wires connected to the thermosensitive body ; a housing that includes an electric insulating resin material, and is configured to house and hold the coil element , the element main body and the paired electric wires ; and a covering body that is configured to cover the element main body and the paired electric wires , the temperature sensor being characterized in that the housing includes, at a position corresponding to the thermosensitive body , a view window allowing for visual confirmation of the thermosensitive body from outside.
A torque sensor comprising: a spindle including a first end which can be operatively connected to a first crank arm and including a second end which can be operatively connected to a second crank arm ; and, characterized by a pair of strain gauge grids , mounted to the spindle at a positive angle or at a negative angle of between about 37°-53° from an axis of the spindle , to measure shear strain in a direction perpendicular to a radius of the spindle , the pair of strain gauge grids including a first strain gauge grid oriented at a first angle of between about 37°-53° from the axis of the spindle and including a second strain gauge grid oriented at a second angle of between about 37°-53° from the axis of the spindle , wherein the first angle may be a positive angle or a negative angle from the axis of the spindle and the second angle may be a positive angle or a negative angle from the axis of the spindle , the pair of strain gauge grids , being electrically connectable to a Wheatstone Bridge arrangement so that bending strains in the spindle measured by the strain gauge grids result in subtractive voltages in the Wheatstone bridge arrangement and torsional strains in the spindle measured by the strain gauge grids result in additive voltages to provide, as strain data, an output voltage (e o ) proportional to torque. a spindle including a first end which can be operatively connected to a first crank arm and including a second end which can be operatively connected to a second crank arm ; and, characterized by a pair of strain gauge grids , mounted to the spindle at a positive angle or at a negative angle of between about 37°-53° from an axis of the spindle , to measure shear strain in a direction perpendicular to a radius of the spindle , the pair of strain gauge grids including a first strain gauge grid oriented at a first angle of between about 37°-53° from the axis of the spindle and including a second strain gauge grid oriented at a second angle of between about 37°-53° from the axis of the spindle , wherein the first angle may be a positive angle or a negative angle from the axis of the spindle and the second angle may be a positive angle or a negative angle from the axis of the spindle , the pair of strain gauge grids , being electrically connectable to a Wheatstone Bridge arrangement so that bending strains in the spindle measured by the strain gauge grids result in subtractive voltages in the Wheatstone bridge arrangement and torsional strains in the spindle measured by the strain gauge grids result in additive voltages to provide, as strain data, an output voltage (e o ) proportional to torque.
4-amino-7-{[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl}-5-[2-(trifluoromethyl)pyrimidin-5-yl]-7H-pyrrolo[2,3-d]pyrimidine-6-carbonitrile or a pharmaceutically acceptable salt thereof.
A method for uplink, UL, transmission in an unlicensed band, the method comprising: receiving, by a wireless device, an UL grant for the UL transmission in the unlicensed band from a base station, BS, wherein the UL grant comprises resource allocation of a physical uplink shared channel, PUSCH, and information on whether a PUSCH type is a truncated PUSCH whose last orthogonal frequency division multiplexing, OFDM, symbol is empty; and transmitting, by the wireless device, a PUSCH in a subframe in the unlicensed band based on the UL grant, wherein the subframe comprises a plurality of OFDM symbols. receiving, by a wireless device, an UL grant for the UL transmission in the unlicensed band from a base station, BS, wherein the UL grant comprises resource allocation of a physical uplink shared channel, PUSCH, and information on whether a PUSCH type is a truncated PUSCH whose last orthogonal frequency division multiplexing, OFDM, symbol is empty; and transmitting, by the wireless device, a PUSCH in a subframe in the unlicensed band based on the UL grant, wherein the subframe comprises a plurality of OFDM symbols.
Assembly comprising a launch motor vehicle and a drone that has a fuselage and wings , the launch motor vehicle being capable of traveling on a launch track so as to exceed a given speed threshold relative to a surrounding air mass, the launch motor vehicle being provided with a launching ramp which engages with the drone in order, in a launch position and while the motor vehicle is traveling on the launch track so as to exceed the given speed threshold relative to the surrounding air mass, to guide the drone in translation from a starting position in a launch direction toward the front of the launch motor vehicle , characterized in that the drone comprises one or more jet engines and does not comprise a landing gear, the wings having a wingspan that fulfils at least one of the following conditions: - the wingspan is greater than a lane width of the launch motor vehicle , - the wingspan is greater than two meters. - the wingspan is greater than a lane width of the launch motor vehicle , - the wingspan is greater than two meters.
A method for detecting decreased preload in a ball screw , which is a method for detecting a decrease in a preload applied to the ball screw , the method comprising: a vibration measurement step of measuring vibration occurring in conjunction with rolling balls during operation of the ball screw ; a calculation processing step of acquiring a vibration value of a vibration signal in a specific frequency band among vibration signals obtained at the vibration measurement step; and an abnormality detection step of determining that a decrease in the preload has occurred in the ball screw when the vibration value is less than a previously determined threshold with respect to a reference value, the reference value being a vibration value in an initial stage of the operation of the ball screw or during a normal operation of the ball screw .
An elastomeric composition for tyre compounds comprising at least - 100 phr of a composition of elastomeric polymers (A) consisting of (A1) 35 to 65 phr of at least one isoprene polymer (IR) having a Tg of between -70 °C and -60 °C, (A2) 15 to 45 phr of at least one styrene-butadiene polymer (SBR) having a Tg of between -70 °C and -55 °C, (A3) 5 to 40 phr of at least one styrene-butadiene polymer (SBR) having a Tg of between -35 °C and -25 °C, the Tg values are measured by dynamo-mechanical analysis (DMA) as reported in the present description, - 5 to 25 phr of at least one resin (B), - 5 to 45 phr of at least one plasticising oil (C), - at least 10 phr of at least one reinforcing filler (D), and - at least 0.5 phr of the at least one vulcanising agent (E), wherein the total amount of plasticiser, including both the resin (B) and the oil (C), is from 25 to 55 phr. - 100 phr of a composition of elastomeric polymers (A) consisting of (A1) 35 to 65 phr of at least one isoprene polymer (IR) having a Tg of between -70 °C and -60 °C, (A2) 15 to 45 phr of at least one styrene-butadiene polymer (SBR) having a Tg of between -70 °C and -55 °C, (A3) 5 to 40 phr of at least one styrene-butadiene polymer (SBR) having a Tg of between -35 °C and -25 °C, the Tg values are measured by dynamo-mechanical analysis (DMA) as reported in the present description, (A1) 35 to 65 phr of at least one isoprene polymer (IR) having a Tg of between -70 °C and -60 °C, (A2) 15 to 45 phr of at least one styrene-butadiene polymer (SBR) having a Tg of between -70 °C and -55 °C, (A3) 5 to 40 phr of at least one styrene-butadiene polymer (SBR) having a Tg of between -35 °C and -25 °C, the Tg values are measured by dynamo-mechanical analysis (DMA) as reported in the present description, - 5 to 25 phr of at least one resin (B), - 5 to 45 phr of at least one plasticising oil (C), - at least 10 phr of at least one reinforcing filler (D), and - at least 0.5 phr of the at least one vulcanising agent (E),
A computer-implemented method for making a clinical diagnosis of a specific cancer type or providing associated information on a specific cancer therapy associated with clinically relevant gene fusion breakpoints, the method being based on disparate sequencing data sets and comprising: (a) detecting a first candidate breakpoint based on a DNA-SEQ data set by comparing the DNA-SEQ data set to a DNA reference sequence data set; (b) detecting a second candidate breakpoint based on a RNA-SEQ data set by comparing the RNA-SEQ data set to both a DNA reference sequence data set and a RNA reference data set; (c) correlating the first and second candidate breakpoints and filtering out weak candidate breakpoints from the correlation of the first and second candidate breakpoints to generate a combined breakpoint list, characterized by a higher threshold specificity and lower false-positive breakpoint detection rate compared to a false-positive breakpoint detection rate in the absence of the correlation; (d) annotating the combined breakpoint list with biologically and clinically relevant information including information related to specific cancer types associated with a detected breakpoint or specific cancer therapies for types of cancer associated with a detected breakpoint to generate an annotated gene fusion data set, wherein the annotated gene fusion data set is suitable for being usedto make a clinical diagnosis of a specific cancer type or providing associated information on a specific cancer therapy associated with a detected breakpoint. (a) detecting a first candidate breakpoint based on a DNA-SEQ data set by comparing the DNA-SEQ data set to a DNA reference sequence data set; (b) detecting a second candidate breakpoint based on a RNA-SEQ data set by comparing the RNA-SEQ data set to both a DNA reference sequence data set and a RNA reference data set; (c) correlating the first and second candidate breakpoints and filtering out weak candidate breakpoints from the correlation of the first and second candidate breakpoints to generate a combined breakpoint list, characterized by a higher threshold specificity and lower false-positive breakpoint detection rate compared to a false-positive breakpoint detection rate in the absence of the correlation; (d) annotating the combined breakpoint list with biologically and clinically relevant information including information related to specific cancer types associated with a detected breakpoint or specific cancer therapies for types of cancer associated with a detected breakpoint to generate an annotated gene fusion data set,