A method for a wireless device served by a first network node on a primary cell, PCell, the wireless device being capable of using at least two secondary serving cells, SCells, the method comprising: receiving a first request to perform a measurement on at least one cell on a first secondary component carrier, SCC, with a deactivated first SCell using at least a first measurement cycle (Block S100); receiving a second request to perform a measurement on at least one cell on a second SCC with a deactivated second SCell using at least a second measurement cycle (Block S102) , wherein the first measurement cycle is used by the wireless device for performing one of mobility measurements and positioning measurements on the first SCC; and the second measurement cycle is used by the wireless device for performing one of mobility measurements and positioning measurements; determining an effective serving cell interruption probability, Peff, of missed at least one of Acknowledgement, ACK, and Negative-Acknowledgement, NACK, signaling in an uplink, UL, direction based on at least the measurements of the first measurement cycle and the second measurement cycle (Block S104); and ensuring that when transmitting packets between a serving cell and the wireless device, a serving cell interruption probability of a missed at least one of ACK and NACK signaling in the UL direction does not exceed the determined effective serving cell interruption probability, Peff, of a missed at least one of ACK and NACK signaling in the UL direction while performing the measurements on the cells of the first SCC and the second SCC (Block S 106), wherein the ensuring that the serving cell interruption probability of missed at least one of ACK and NACK signaling in the UL direction does not exceed the determined effective serving cell interruption probability, Peff, of missed at least one of ACK and NACK signaling includes adapting at least one radio procedure to be performed by the wireless device. receiving a first request to perform a measurement on at least one cell on a first secondary component carrier, SCC, with a deactivated first SCell using at least a first measurement cycle (Block S100); receiving a second request to perform a measurement on at least one cell on a second SCC with a deactivated second SCell using at least a second measurement cycle (Block S102) , wherein the first measurement cycle is used by the wireless device for performing one of mobility measurements and positioning measurements on the first SCC; and the second measurement cycle is used by the wireless device for performing one of mobility measurements and positioning measurements; determining an effective serving cell interruption probability, Peff, of missed at least one of Acknowledgement, ACK, and Negative-Acknowledgement, NACK, signaling in an uplink, UL, direction based on at least the measurements of the first measurement cycle and the second measurement cycle (Block S104); and ensuring that when transmitting packets between a serving cell and the wireless device, a serving cell interruption probability of a missed at least one of ACK and NACK signaling in the UL direction does not exceed the determined effective serving cell interruption probability, Peff, of a missed at least one of ACK and NACK signaling in the UL direction while performing the measurements on the cells of the first SCC and the second SCC (Block S 106), wherein the ensuring that the serving cell interruption probability of missed at least one of ACK and NACK signaling in the UL direction does not exceed the determined effective serving cell interruption probability, Peff, of missed at least one of ACK and NACK signaling includes adapting at least one radio procedure to be performed by the wireless device. <EOS>