mhurhangee/patent-ind-claim-en huggingface dataset:
A method for determining if a subject afflicted with bladder cancer is at risk for metastasis, wherein the method comprises: (a) detecting circulating tumor cells (CTCs) that express PD-L1 in a liquid biopsy sample from the subject afflicted with bladder cancer; (b) calculating what proportion of CTCs in the liquid biopsy that express PD-L1 is cytokeratin (CK)-negative; and (c) identifying the subject as a candidate at risk for metastasis based on an assessment that the proportion of CK-negative CTCs in the liquid biopsy that express PD-L1 exceeds a predetermined threshold level. (a) detecting circulating tumor cells (CTCs) that express PD-L1 in a liquid biopsy sample from the subject afflicted with bladder cancer; (b) calculating what proportion of CTCs in the liquid biopsy that express PD-L1 is cytokeratin (CK)-negative; and (c) identifying the subject as a candidate at risk for metastasis based on an assessment that the proportion of CK-negative CTCs in the liquid biopsy that express PD-L1 exceeds a predetermined threshold level.
An installation for heating cryogenic fuel supplying the combustion chamber of an aircraft turbine engine , this installation comprising: - a storage tank for said cryogenic fuel in the liquid state, - a supply line configured to connect said tank to said combustion chamber of the aircraft turbine engine, - a closed circuit for circulation of a heat-transfer fluid, - a cryogenic fuel/heat-transfer fluid heat exchanger and at least one heat-transfer fluid/working fluid heat exchanger , mounted in series in said closed circuit , the cryogenic fuel/heat-transfer fluid heat exchanger enabling heating of the cryogenic fuel by an input of heat delivered by the heat-transfer fluid, characterised in that the closed circuit for circulation of the heat-transfer fluid comprises a pump for circulating said heat-transfer fluid and a closed expansion vessel , connected to said closed circuit upstream of said pump with respect to the direction of circulation of the heat-transfer fluid in the closed circuit , and in that said pump is controlled by a central unit so as to ensure a heat-transfer fluid flow rate inside the closed circuit which enables cooling of the working fluid or fluids and heating of the cryogenic fuel according to the operating phases of the aircraft, and so that the closed expansion vessel keeps the heat-transfer fluid circulating in said closed circuit at a pressure such that it remains in the liquid state and does not change phase, in that the installation comprises at least two heat-transfer fluid/working fluid heat exchangers , including a heat exchanger between the heat-transfer fluid and the bleed air taken at the outlet of the turbine engine compressor and a heat exchanger between the heat-transfer fluid and the air cooling the turbine blade and in that the heat exchanger between the heat-transfer fluid and the bleed air taken at the outlet of the turbine engine compressor is disposed upstream of the heat exchanger between the heat-transfer fluid and the air cooling the turbine blades or upstream of the heat exchanger between the heat-transfer fluid and the air cooling the turbine blades and of the other heat-transfer fluid/working fluid heat exchangers , with respect to the direction of circulation of the heat-transfer fluid in the closed circuit . - a storage tank for said cryogenic fuel in the liquid state, - a supply line configured to connect said tank to said combustion chamber of the aircraft turbine engine, - a closed circuit for circulation of a heat-transfer fluid, - a cryogenic fuel/heat-transfer fluid heat exchanger and at least one heat-transfer fluid/working fluid heat exchanger , mounted in series in said closed circuit , the cryogenic fuel/heat-transfer fluid heat exchanger enabling heating of the cryogenic fuel by an input of heat delivered by the heat-transfer fluid,
A chilling panel comprising: a casing layer having thermal insulating properties and forming an exterior side of the chilling panel; a coolant compartment defined by thermally conductive side walls abutting an interior side of the casing layer and configured to contain a cooling element ; an inner wall layer constructed of thermally conductive material and forming the interior side of the chilling panel; a liquid reservoir compartment defined as the volume between the inner wall layer and a combination of the coolant compartment and the casing layer , the liquid reservoir compartment being substantially filled with water when in use; an internal thermal insulator layer positioned between the liquid reservoir compartment and the coolant compartment , the internal thermal insulator layer being positioned and sized such that water stored in the liquid reservoir compartment is thermally insulated from the cooling element in the coolant compartment on a surface of the coolant compartment parallel with a major plane of the chilling plane; and a means for selectively interconnecting the chilling panel with a number of other chilling panels having a similar structure to form a sealed container. a casing layer having thermal insulating properties and forming an exterior side of the chilling panel; a coolant compartment defined by thermally conductive side walls abutting an interior side of the casing layer and configured to contain a cooling element ; an inner wall layer constructed of thermally conductive material and forming the interior side of the chilling panel; a liquid reservoir compartment defined as the volume between the inner wall layer and a combination of the coolant compartment and the casing layer , the liquid reservoir compartment being substantially filled with water when in use; an internal thermal insulator layer positioned between the liquid reservoir compartment and the coolant compartment , the internal thermal insulator layer being positioned and sized such that water stored in the liquid reservoir compartment is thermally insulated from the cooling element in the coolant compartment on a surface of the coolant compartment parallel with a major plane of the chilling plane; and a means for selectively interconnecting the chilling panel with a number of other chilling panels having a similar structure to form a sealed container.
A method for the treatment of biosludge, wherein the method comprises - mixing biosludge with a bio-based material to form a mixture, wherein the dry matter of the biosludge is at least 0.01 % (w/w) of the total dry matter of the mixture, and wherein the bio-based material is bark; - treating the mixture at a temperature in the range of 160 -295°C under pressure in the presence of steam; and - releasing the pressure suddenly or explosively to disrupt the structure of the mixture. - mixing biosludge with a bio-based material to form a mixture, wherein the dry matter of the biosludge is at least 0.01 % (w/w) of the total dry matter of the mixture, and wherein the bio-based material is bark; - treating the mixture at a temperature in the range of 160 -295°C under pressure in the presence of steam; and - releasing the pressure suddenly or explosively to disrupt the structure of the mixture.
A system for percutaneous, transcatheter heart valve repair, the system comprising: a catheter configured to provide percutaneous access into a heart of a patient; an adjustable annuloplasty ring comprising: a body member that is transitionable from an elongate insertion geometry to an annular operable geometry, the elongate insertion geometry configured to allow percutaneous passage of the annuloplasty ring , via the catheter , into the heart of a patient, and the annular operable geometry having an expanded state to conform to an annulus of a target valve of the heart and a contracted state to reduce a diameter of the annulus of the target valve, and a plurality of anchors deployable in the annular operable geometry to engage the annulus of the target valve; and a stabilizer comprising a plurality of prongs configured to engage the annuloplasty ring in the annular operable geometry within the heart to enable percutaneous manipulation of the ring to orient and position the ring in intimate contact with the annulus of the target valve. a catheter configured to provide percutaneous access into a heart of a patient; an adjustable annuloplasty ring comprising: a body member that is transitionable from an elongate insertion geometry to an annular operable geometry, the elongate insertion geometry configured to allow percutaneous passage of the annuloplasty ring , via the catheter , into the heart of a patient, and the annular operable geometry having an expanded state to conform to an annulus of a target valve of the heart and a contracted state to reduce a diameter of the annulus of the target valve, and a plurality of anchors deployable in the annular operable geometry to engage the annulus of the target valve; and a stabilizer comprising a plurality of prongs configured to engage the annuloplasty ring in the annular operable geometry within the heart to enable percutaneous manipulation of the ring to orient and position the ring in intimate contact with the annulus of the target valve. a body member that is transitionable from an elongate insertion geometry to an annular operable geometry, the elongate insertion geometry configured to allow percutaneous passage of the annuloplasty ring , via the catheter , into the heart of a patient, and the annular operable geometry having an expanded state to conform to an annulus of a target valve of the heart and a contracted state to reduce a diameter of the annulus of the target valve, and a plurality of anchors deployable in the annular operable geometry to engage the annulus of the target valve; and a stabilizer comprising a plurality of prongs configured to engage the annuloplasty ring in the annular operable geometry within the heart to enable percutaneous manipulation of the ring to orient and position the ring in intimate contact with the annulus of the target valve.
A method for predicting the risk of cardiovascular disease comprises: a. in a first urine sample that has been obtained from a Type-II diabetic patient at a first time period; b. determining the expression level of the genes coding for nephrin and podocin, and measuring the levels of albumin and podocin; c. comparing the expression levels of the genes coding for nephrin and podocin at the first time period to a baseline of nephrin and podocin of at least between 0.2 and 2 million copies/ml, wherein the first time period is before the onset of any cardiovascular disease event; and d. predicting the time until a cardiovascular disease event in the Type-II diabetic patient based on the outcome of the comparison of the expression levels of the at least two genes of interest at different time periods, wherein any statistical significant increase from about 0.2 to 2 million copies as measured in the urine sample of the Type-II diabetic patient having a normal albuminuria during the first time period indicates a subject is at risk for developing cardiovascular disease, and wherein the cardiovascular disease event is selected from the group consisting of coronary artery disease, myocardial infarction, heart failure, cerebrovascular accident (stroke) and PVD. a. in a first urine sample that has been obtained from a Type-II diabetic patient at a first time period; b. determining the expression level of the genes coding for nephrin and podocin, and measuring the levels of albumin and podocin; c. comparing the expression levels of the genes coding for nephrin and podocin at the first time period to a baseline of nephrin and podocin of at least between 0.2 and 2 million copies/ml, wherein the first time period is before the onset of any cardiovascular disease event; and d. predicting the time until a cardiovascular disease event in the Type-II diabetic patient based on the outcome of the comparison of the expression levels of the at least two genes of interest at different time periods, wherein any statistical significant increase from about 0.2 to 2 million copies as measured in the urine sample of the Type-II diabetic patient having a normal albuminuria during the first time period indicates a subject is at risk for developing cardiovascular disease, and wherein the cardiovascular disease event is selected from the group consisting of coronary artery disease, myocardial infarction, heart failure, cerebrovascular accident (stroke) and PVD.
A connection device for connecting a first tube end adapted to be connected to a vacuum pump to a second tube end adapted to be connected to a chamber to be evacuated, comprising a tube element for fluidically connecting said vacuum pump to said chamber to be evacuated, wherein said tube element comprises a connection element on each side for connection to a respective one of said tube ends , wherein, in operation, at least one of said two connection elements is exclusively suitable for transmitting torques, and a decoupling element for the mechanical axial decoupling of said at least one connection element , which is exclusively suitable for transmitting torques, from said corresponding tube end . characterized in that the decoupling element comprises at least one fluid chamber filled with a compressible fluid, in particular gas. a tube element for fluidically connecting said vacuum pump to said chamber to be evacuated, wherein said tube element comprises a connection element on each side for connection to a respective one of said tube ends , wherein, in operation, at least one of said two connection elements is exclusively suitable for transmitting torques, and a decoupling element for the mechanical axial decoupling of said at least one connection element , which is exclusively suitable for transmitting torques, from said corresponding tube end . characterized in that the decoupling element comprises at least one fluid chamber filled with a compressible fluid, in particular gas.
A liquid jet head comprising: a flow channel member provided with a flow channel for a liquid, and having a higher heat conduction part exposed to the inside of the flow channel so as to have contact with the liquid flowing inside the flow channel, and a lower heat conduction part having a lower thermal conductivity than a thermal conductivity of the higher heat conduction part; a temperature detection element disposed outside the flow channel, and attached to the higher heat conduction part; and a liquid jet section from which the liquid is jetted; characterized by a first adhesive disposed between the temperature detection element and the higher heat conduction part so as to bond the temperature detection element to the higher heat conduction part; and a second adhesive having a lower thermal conductivity than a thermal conductivity of the first adhesive, and being disposed in contact with at least a part of the temperature detection element other than a part bonded to the higher heat conduction part. a flow channel member provided with a flow channel for a liquid, and having a higher heat conduction part exposed to the inside of the flow channel so as to have contact with the liquid flowing inside the flow channel, and a lower heat conduction part having a lower thermal conductivity than a thermal conductivity of the higher heat conduction part; a temperature detection element disposed outside the flow channel, and attached to the higher heat conduction part; and a liquid jet section from which the liquid is jetted; characterized by a first adhesive disposed between the temperature detection element and the higher heat conduction part so as to bond the temperature detection element to the higher heat conduction part; and a second adhesive having a lower thermal conductivity than a thermal conductivity of the first adhesive, and being disposed in contact with at least a part of the temperature detection element other than a part bonded to the higher heat conduction part.
A neckwear, comprising: a neckband ; a neckband module ; at least one display segment ; at least one fastener ; and a first coin , medal or bullion bar , said neckband module including a compartment containing the first coin , medal or bullion bar , and said neckband module displaying the first coin , medal or bullion bar ; characterized in that : the neckwear further comprises a second coin , medal or bullion bar , said at least one display segment including a compartment containing the second coin , medal or bullion bar , and said at least one display segment displaying the second coin , medal or bullion bar , said neckband connects to said neckband module , and said neckband module connects to said at least one display segment ; said at least one fastener includes a first fastener, said first fastener pivotably connecting said neckband module to said at least one display segment ; said first coin , medal or bullion bar and said second coin , medal or bullion bar are intra-changeable with one another; and said first coin , medal or bullion bar and said second coin , medal or bullion bar comprise silver, gold or platinum. a neckband ; a neckband module ; at least one display segment ; at least one fastener ; and a first coin , medal or bullion bar , said neckband module including a compartment containing the first coin , medal or bullion bar , and said neckband module displaying the first coin , medal or bullion bar ; characterized in that : the neckwear further comprises a second coin , medal or bullion bar , said at least one display segment including a compartment containing the second coin , medal or bullion bar , and said at least one display segment displaying the second coin , medal or bullion bar , said neckband connects to said neckband module , and said neckband module connects to said at least one display segment ; said at least one fastener includes a first fastener, said first fastener pivotably connecting said neckband module to said at least one display segment ; said first coin , medal or bullion bar and said second coin , medal or bullion bar are intra-changeable with one another; and said first coin , medal or bullion bar and said second coin , medal or bullion bar comprise silver, gold or platinum. the neckwear further comprises a second coin , medal or bullion bar , said at least one display segment including a compartment containing the second coin , medal or bullion bar , and said at least one display segment displaying the second coin , medal or bullion bar , said neckband connects to said neckband module , and said neckband module connects to said at least one display segment ; said at least one fastener includes a first fastener, said first fastener pivotably connecting said neckband module to said at least one display segment ; said first coin , medal or bullion bar and said second coin , medal or bullion bar are intra-changeable with one another; and said first coin , medal or bullion bar and said second coin , medal or bullion bar comprise silver, gold or platinum.
An oscillator comprising: an amplifier array including a plurality of inverting amplifiers connected in parallel; a buffer coupled to the amplifier array and configured to generate an output signal of the oscillator , wherein the output signal is an oscillating signal at a desired frequency; a control logic unit coupled to the amplifier array and configured to activate and deactivate one or more inverting amplifiers of the plurality of inverting amplifiers based on both a controlled clock and the output signal ; a self-clock generating circuit coupled to the control logic unit and configured to generate a fixed clock; and a counter configured to receive the fixed clock from the self-clock generating circuit and configured to provide the controlled clock to the control logic unit ; wherein the control logic unit is configured to first activate the plurality of inverting amplifiers (204a, 204b, ..., 204n) upon receiving the controlled clock and then, if no oscillations are detected in the output signal , repeatedly, after each time t determined by the controlled clock, deactivate some inverting amplifiers of the plurality of inverting amplifiers until the control logic unit detects oscillations in the output signal . an amplifier array including a plurality of inverting amplifiers connected in parallel; a buffer coupled to the amplifier array and configured to generate an output signal of the oscillator , wherein the output signal is an oscillating signal at a desired frequency; a control logic unit coupled to the amplifier array and configured to activate and deactivate one or more inverting amplifiers of the plurality of inverting amplifiers based on both a controlled clock and the output signal ; a self-clock generating circuit coupled to the control logic unit and configured to generate a fixed clock; and a counter configured to receive the fixed clock from the self-clock generating circuit and configured to provide the controlled clock to the control logic unit ; wherein the control logic unit is configured to first activate the plurality of inverting amplifiers (204a, 204b, ..., 204n) upon receiving the controlled clock and then, if no oscillations are detected in the output signal , repeatedly, after each time t determined by the controlled clock, deactivate some inverting amplifiers of the plurality of inverting amplifiers until the control logic unit detects oscillations in the output signal .
A method for discharging a hybrid battery system in an electric vehicle, the battery system being designed to supply a discharging current to an electric motor for driving the electric vehicle and the battery system comprising at least one high energy battery and at least one high power battery , whereat the at least one high energy battery supplies a discharging current to the electric motor when a speed of the electric vehicle is higher than a determined first speed value, and whereat the at least one high power battery supplies a discharging current to the electric motor when the speed of the electric vehicle is lower than the determined first speed value or the high power battery exclusively supplies a discharging current to the electric motor when a state of charge of the high energy battery is lower than a determined first level and when the state of charge of the high power battery is higher than a determined second level. the battery system being designed to supply a discharging current to an electric motor for driving the electric vehicle and the battery system comprising at least one high energy battery and at least one high power battery , whereat the at least one high energy battery supplies a discharging current to the electric motor when a speed of the electric vehicle is higher than a determined first speed value, and whereat the at least one high power battery supplies a discharging current to the electric motor when the speed of the electric vehicle is lower than the determined first speed value or the high power battery exclusively supplies a discharging current to the electric motor when a state of charge of the high energy battery is lower than a determined first level and when the state of charge of the high power battery is higher than a determined second level.