An optical tomography scanning system for 3D imaging of an associated object , such as non-invasive 3D imaging of, at least part of, a patient or an animal, using Raman scattered light from said object, said system comprising: - a monochromatic light source arranged for illuminating said object, - an optical configuration for fixating said object and arranged for rotating to a plurality of relative rotational positions (Θ) between said object and the optical tomography scanning system, - an optical receiving part optically arranged relative to said object for receiving Raman scattered light from said object, the optical receiving part comprising: - a detector array arranged for receiving the Raman scattered light in two spatial dimensions (X, Z), and - a plurality of optical guide means arranged for receiving and conveying further said Raman scattered light to a spectrometer for recording into multiple spectra upon acquiring in said two spatial dimensions for each relative rotational position (Θ) of said object, and wherein the Raman scattered light from said object detected by said optical receiving part displays an anisotropic polar plot as a function of said relative rotational position (Θ) corresponding to the internal spatial structure of said object, and - a processing part arranged for 3D image reconstruction of said object based on said recorded multiple spectra based on a plurality of relative rotational positions (Θ) of said object, characterised by using said anisotropic polar plot as a function of said relative rotational position (Θ) corresponding to the internal spatial structure of said object. - a monochromatic light source arranged for illuminating said object, - an optical configuration for fixating said object and arranged for rotating to a plurality of relative rotational positions (Θ) between said object and the optical tomography scanning system, - an optical receiving part optically arranged relative to said object for receiving Raman scattered light from said object, the optical receiving part comprising: - a detector array arranged for receiving the Raman scattered light in two spatial dimensions (X, Z), and - a plurality of optical guide means arranged for receiving and conveying further said Raman scattered light to a spectrometer for recording into multiple spectra upon acquiring in said two spatial dimensions for each relative rotational position (Θ) of said object, and wherein the Raman scattered light from said object detected by said optical receiving part displays an anisotropic polar plot as a function of said relative rotational position (Θ) corresponding to the internal spatial structure of said object, and - a detector array arranged for receiving the Raman scattered light in two spatial dimensions (X, Z), and - a plurality of optical guide means arranged for receiving and conveying further said Raman scattered light to a spectrometer for recording into multiple spectra upon acquiring in said two spatial dimensions for each relative rotational position (Θ) of said object, and - a processing part arranged for 3D image reconstruction of said object based on said recorded multiple spectra based on a plurality of relative rotational positions (Θ) of said object, characterised by using said anisotropic polar plot as a function of said relative rotational position (Θ) corresponding to the internal spatial structure of said object. <EOS>