mhurhangee/patent-ind-claim-en huggingface dataset:
A catheter, comprising: a flexible tubing; and a control handle proximal of the flexible tubing, the control handle having: a barrel housing and a piston in a telescopic configuration, the piston having a thumb control, the piston configured for longitudinal movement relative to the barrel housing by a user via the thumb control for deflecting the tubing; and a tension adjustment assembly including: a force member adapted for applying a force on the piston; a knob rotationally coupled to the force member, the knob adapted for rotation by the user to adjust the force applied on the piston by the force member, and characterized in that the tension adjustment assembly further comprises a guide configured to limit the range of rotation of the knob so as to prevent damage to the piston or barrel housing, or disassembly or detachment of the tension adjustment assembly. a flexible tubing; and a control handle proximal of the flexible tubing, the control handle having: a barrel housing and a piston in a telescopic configuration, the piston having a thumb control, the piston configured for longitudinal movement relative to the barrel housing by a user via the thumb control for deflecting the tubing; and a tension adjustment assembly including: a force member adapted for applying a force on the piston; a knob rotationally coupled to the force member, the knob adapted for rotation by the user to adjust the force applied on the piston by the force member, and characterized in that the tension adjustment assembly further comprises a guide configured to limit the range of rotation of the knob so as to prevent damage to the piston or barrel housing, or disassembly or detachment of the tension adjustment assembly. a barrel housing and a piston in a telescopic configuration, the piston having a thumb control, the piston configured for longitudinal movement relative to the barrel housing by a user via the thumb control for deflecting the tubing; and a tension adjustment assembly including: a force member adapted for applying a force on the piston; a knob rotationally coupled to the force member, the knob adapted for rotation by the user to adjust the force applied on the piston by the force member, and characterized in that the tension adjustment assembly further comprises a guide configured to limit the range of rotation of the knob so as to prevent damage to the piston or barrel housing, or disassembly or detachment of the tension adjustment assembly. a force member adapted for applying a force on the piston; a knob rotationally coupled to the force member, the knob adapted for rotation by the user to adjust the force applied on the piston by the force member, and characterized in that the tension adjustment assembly further comprises a guide configured to limit the range of rotation of the knob so as to prevent damage to the piston or barrel housing, or disassembly or detachment of the tension adjustment assembly.
A method of making a modified IgG2 anti-EGFR antibody comprising: modifying a nucleotide sequence encoding the heavy chain polypeptide of an IgG2 anti-EGFR antibody such that at least one encoded amino acid is modified; introducing said nucleic acid into a host cell; and culturing said host cell such that a plurality of modified IgG2 anti-EGFR antibodies is expressed and secreted, wherein a substantial population that is at least 50% of the total population of said plurality of modified IgG2 antibodies are a single conformational isoform, wherein said modification comprises a heavy chain polypeptide modification of said antibody, and wherein said heavy chain polypeptide modification comprises a substitution of the cysteine residue at Eu position 131 of said heavy chain polypeptide with serine (C131S), and wherein said heavy chain polypeptide modification further comprises a mutation of a cysteine residue within the hinge region, and wherein said mutation of a cysteine residue within said hinge region of said heavy chain polypeptide comprises a mutation of the cysteine residue at Eu position 219 or 220 of said heavy chain polypeptide to serine (C219S or C220S), and wherein the heavy chain of said modified IgG2 anti-EGFR antibody comprises the variable region SEQ ID NO: 57. modifying a nucleotide sequence encoding the heavy chain polypeptide of an IgG2 anti-EGFR antibody such that at least one encoded amino acid is modified; introducing said nucleic acid into a host cell; and culturing said host cell such that a plurality of modified IgG2 anti-EGFR antibodies is expressed and secreted, wherein a substantial population that is at least 50% of the total population of said plurality of modified IgG2 antibodies are a single conformational isoform, wherein said modification comprises a heavy chain polypeptide modification of said antibody, and wherein said heavy chain polypeptide modification comprises a substitution of the cysteine residue at Eu position 131 of said heavy chain polypeptide with serine (C131S), and wherein said heavy chain polypeptide modification further comprises a mutation of a cysteine residue within the hinge region, and wherein said mutation of a cysteine residue within said hinge region of said heavy chain polypeptide comprises a mutation of the cysteine residue at Eu position 219 or 220 of said heavy chain polypeptide to serine (C219S or C220S), and wherein the heavy chain of said modified IgG2 anti-EGFR antibody comprises the variable region SEQ ID NO: 57.
A cannabidiol (CBD) preparation for use in the treatment of seizures associated with autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) with DEPDC5 mutation.
A computer implemented method comprising: receiving an input defining a particular key phrase; receiving an audio data stream ; determining whether a portion of the audio data stream encodes a particular key phrase by analyzing the portion using an automated speech recognizer ; in response to determining that the portion of the audio data stream does not encode the particular key phrase, determining to skip modifying the audio data stream to include an audio watermark based on the portion of the audio data stream that does not encode the particular key phrase and after determining to skip modifying the audio data stream to include the audio watermark based on the portion of the audio data stream that does not encode the particular key phrase, providing the audio data stream for output ; and in response to determining that the portion of the audio data stream encodes the particular key phrase, modifying the audio data stream to include an audio watermark , and providing the modified audio data stream for output . receiving an input defining a particular key phrase; receiving an audio data stream ; determining whether a portion of the audio data stream encodes a particular key phrase by analyzing the portion using an automated speech recognizer ; in response to determining that the portion of the audio data stream does not encode the particular key phrase, determining to skip modifying the audio data stream to include an audio watermark based on the portion of the audio data stream that does not encode the particular key phrase and after determining to skip modifying the audio data stream to include the audio watermark based on the portion of the audio data stream that does not encode the particular key phrase, providing the audio data stream for output ; and in response to determining that the portion of the audio data stream encodes the particular key phrase, modifying the audio data stream to include an audio watermark , and providing the modified audio data stream for output .
Detection circuit comprising: - a detector having a stray capacitor (C PD ), and configured to deliver electric charges according to an observed phenomenon, - a bias circuit configured to bias the detector during a first period and to leave a first terminal of the detector at a floating potential during a second period, circuit characterized in that it comprises - a first capacitor (C INT ) having a first terminal connected to the first terminal of the detector to form an integration node (N) with the stray capacitor (C PD ), the integration node (N) being at a target value during the first period and at a changing value during the second period, - a transfer circuit configured to transfer electric charges from the stray capacitor (C PD ) to the first capacitor (C INT ), the transfer circuit being configured to bias a second terminal of the first capacitor (C INT ) so as to shift the potential of the integration node (N) to the target value and to disable transfer of the electric charges when the potential of the integration node reaches a predefined value, - an output terminal delivering a voltage representative of the potential present on the second terminal of the first capacitor (C INT ). - a detector having a stray capacitor (C PD ), and configured to deliver electric charges according to an observed phenomenon, - a bias circuit configured to bias the detector during a first period and to leave a first terminal of the detector at a floating potential during a second period, - a first capacitor (C INT ) having a first terminal connected to the first terminal of the detector to form an integration node (N) with the stray capacitor (C PD ), the integration node (N) being at a target value during the first period and at a changing value during the second period, - a transfer circuit configured to transfer electric charges from the stray capacitor (C PD ) to the first capacitor (C INT ), the transfer circuit being configured to bias a second terminal of the first capacitor (C INT ) so as to shift the potential of the integration node (N) to the target value and to disable transfer of the electric charges when the potential of the integration node reaches a predefined value, - an output terminal delivering a voltage representative of the potential present on the second terminal of the first capacitor (C INT ).
A heat exchanger comprising (i) a set of plates made of a plastic material, including two end plates and a plurality of juxtaposed intermediate plates extending between the two end plates , a set of first spaces and, isolated from the set of first spaces , a set of second spaces delimited by the adjacent plates , the first spaces being intended for a circulation of a first fluid between the plates and the second spaces being intended for a circulation of a second fluid between the plates , the heat exchanger being characterized in that it comprises (ii) a base portion against which the two end plates are fastened, the plurality of plates extending in a curvilinear manner between the two ends plates .
An induction cooking apparatus comprising: a plate ; two metal members disposed on the plate ; a first coil (Lr1) disposed under the plate ; a second coil (Lr2) disposed under the plate and around the first coil (Lr1); and a temperature detector disposed on the plate and including a resistor element (420, Rv) having a resistance value changed according to a temperature of a cooking vessel which, in use, is induction-heated by the second coil (Lr2), characterized in that : the resistor element (420, Rv) is disposed between the two metal members , and the cooking vessel is placeable on the resistor element (420 or Rv), whereby the first coil (Lr1) intermittently operates to sense the temperature of the cooking vessel based on current flowing in the resistor element. a plate ; two metal members disposed on the plate ; a first coil (Lr1) disposed under the plate ; a second coil (Lr2) disposed under the plate and around the first coil (Lr1); and a temperature detector disposed on the plate and including a resistor element (420, Rv) having a resistance value changed according to a temperature of a cooking vessel which, in use, is induction-heated by the second coil (Lr2), characterized in that : the resistor element (420, Rv) is disposed between the two metal members , and the cooking vessel is placeable on the resistor element (420 or Rv), whereby the first coil (Lr1) intermittently operates to sense the temperature of the cooking vessel based on current flowing in the resistor element.
A swash plate compressor comprising a cylinder block configured to accommodate a piston for compressing a refrigerant, a front housing coupled to a front side of the cylinder block and having a crank chamber , a rear housing having a suction chamber and a discharge chamber and coupled to a rear side of the cylinder block , a gasket inserted into the cylinder block , and a suction reed plate inserted between a valve plate and the cylinder block , the swash plate compressor comprising: a first orifice hole through which the refrigerant in the crank chamber can pass; a second orifice hole configured to communicate with the suction chamber and discharge the refrigerant passing through the first orifice hole to the suction chamber ; an intermediate flow path configured to connect the first orifice hole and the second orifice hole ; and the valve plate inserted between the cylinder block and the rear housing and having a suction chamber pressure-maintaining space connected to the suction chamber and configured to maintain a pressure equal to a pressure in the suction chamber , characterized in that the valve plate comprises: a first valve plate through hole penetratively formed in the valve plate to connect the suction chamber pressure-maintaining space and the suction chamber ; and a second valve plate through hole penetratively formed in the valve plate and spaced apart from the first valve plate through hole . a first orifice hole through which the refrigerant in the crank chamber can pass; a second orifice hole configured to communicate with the suction chamber and discharge the refrigerant passing through the first orifice hole to the suction chamber ; an intermediate flow path configured to connect the first orifice hole and the second orifice hole ; and the valve plate inserted between the cylinder block and the rear housing and having a suction chamber pressure-maintaining space connected to the suction chamber and configured to maintain a pressure equal to a pressure in the suction chamber , characterized in that the valve plate comprises: a first valve plate through hole penetratively formed in the valve plate to connect the suction chamber pressure-maintaining space and the suction chamber ; and a second valve plate through hole penetratively formed in the valve plate and spaced apart from the first valve plate through hole . a first valve plate through hole penetratively formed in the valve plate to connect the suction chamber pressure-maintaining space and the suction chamber ; and a second valve plate through hole penetratively formed in the valve plate and spaced apart from the first valve plate through hole .
Composition for producing a thermoplastic moulding material, wherein the composition contains the following constituents: A) aromatic polycarbonate or polyestercarbonate, B) rubber-modified vinyl (co)polymer, C) a hydrocarbon resin containing aromatic and aliphatic structural units, D) optionally further additives distinct from component C, characterized in that for the component C the ratio of the integrated peak area of the FTIR spectrum in the wavenumber range 1630 cm-1 to 1560 cm-1 to the integrated peak area of the FTIR spectrum in the wavenumber range 1520 cm-1 to 1350 cm-1 is in the range of (80-160)·10 -3 . A) aromatic polycarbonate or polyestercarbonate, B) rubber-modified vinyl (co)polymer, C) a hydrocarbon resin containing aromatic and aliphatic structural units, D) optionally further additives distinct from component C,
Packaging system of at least one rigid product , wherein it is adapted to perform an on-site packaging of said rigid product by placing onto said rigid product at least one coating element by at least one user of said packaging system and/or at least one consumer of said rigid product , said packaging system being composed of: - at least one containing element adapted to wrap and to contain therein said coating element possibly equipped with at least one graphic representation; - at least one loading means equipped with at least one access element , adapted to enable an insertion and a withdrawal by said user and/or consumer of said rigid product inside said loading means ; - at least one actuator device, adapted to place said coating element onto said rigid product ; characterised in further comprising: - at least one rotor means equipped with a plurality of housings , each adapted to contain said containing element , said containing element having said coating element being placed in one of said plurality of housings placed in said rotor means in a final position, such that said rigid product is wrapped with said coating element . - at least one containing element adapted to wrap and to contain therein said coating element possibly equipped with at least one graphic representation; - at least one loading means equipped with at least one access element , adapted to enable an insertion and a withdrawal by said user and/or consumer of said rigid product inside said loading means ; - at least one actuator device, adapted to place said coating element onto said rigid product ; characterised in further comprising: - at least one rotor means equipped with a plurality of housings , each adapted to contain said containing element , said containing element having said coating element being placed in one of said plurality of housings placed in said rotor means in a final position, such that said rigid product is wrapped with said coating element . - at least one rotor means equipped with a plurality of housings , each adapted to contain said containing element , said containing element having said coating element being placed in one of said plurality of housings placed in said rotor means in a final position, such that said rigid product is wrapped with said coating element .
A chip module , comprising a plurality of first ports and a first control module , wherein at least some of the plurality of first ports are first selection ports , and each first selection port acts as a read port or a write port; and the first control module is configured to control, based on a transmit/receive requirement of the chip module , the first selection port to be switched to a read port or a write port, to match the transmit/receive requirement of the chip module ; characterized in that : the first control module is further configured to: obtain a required ratio of write ports to read ports as a target ratio based on the transmit/receive requirement of the chip module , and to determine a current ratio of write ports to read ports in the current chip module ; and when the current ratio is different from the target ratio, the first control module is configured to control, based on a result of comparison between the target ratio and the current ratio, the first selection port to be switched to a read port or a write port, until the ratio of read ports to write ports of the chip module is consistent with the target ratio. at least some of the plurality of first ports are first selection ports , and each first selection port acts as a read port or a write port; and the first control module is configured to control, based on a transmit/receive requirement of the chip module , the first selection port to be switched to a read port or a write port, to match the transmit/receive requirement of the chip module ; characterized in that : the first control module is further configured to: obtain a required ratio of write ports to read ports as a target ratio based on the transmit/receive requirement of the chip module , and to determine a current ratio of write ports to read ports in the current chip module ; and when the current ratio is different from the target ratio, the first control module is configured to control, based on a result of comparison between the target ratio and the current ratio, the first selection port to be switched to a read port or a write port, until the ratio of read ports to write ports of the chip module is consistent with the target ratio. the first control module is further configured to: obtain a required ratio of write ports to read ports as a target ratio based on the transmit/receive requirement of the chip module , and to determine a current ratio of write ports to read ports in the current chip module ; and when the current ratio is different from the target ratio, the first control module is configured to control, based on a result of comparison between the target ratio and the current ratio, the first selection port to be switched to a read port or a write port, until the ratio of read ports to write ports of the chip module is consistent with the target ratio.
A child-resistant aerosol cap comprising a base which is attachable onto an aerosol container, and a lid which is attachable to the base, the lid includes locking means for releasably locking the lid onto the base, characterised in that the base is provided with means for preventing rotation relative to the aerosol container.
A splash guard for a grinder polisher having a base , a bowl , and a platen having an outer edge, the splash guard comprising: an inner sidewall having a first end and a second end , and configured to engage with the base such that the first end extends from the base and surrounds the bowl ; a lower rib having an inner edge and an outer edge (1 03b), and extending from the second end of the inner side wall ; an outer sidewall having a first end and a second end , and extending from the outer edge 103b) of the lower rib such that the first end of the outer sidewall is proximate the outer edge of the lower rib ; and an upper rib having an inner edge and an outer edge , and extending inwardly from the second end of the outer sidewall such that the outer edge of the upper rib is proximate the second end of the outer sidewall ; and wherein the inner edge of the lower rib is configured to be, in use, spaced at least 2.5 centimeters from the outer edge of the platen . an inner sidewall having a first end and a second end , and configured to engage with the base such that the first end extends from the base and surrounds the bowl ; a lower rib having an inner edge and an outer edge (1 03b), and extending from the second end of the inner side wall ; an outer sidewall having a first end and a second end , and extending from the outer edge 103b) of the lower rib such that the first end of the outer sidewall is proximate the outer edge of the lower rib ; and an upper rib having an inner edge and an outer edge , and extending inwardly from the second end of the outer sidewall such that the outer edge of the upper rib is proximate the second end of the outer sidewall ; and wherein the inner edge of the lower rib is configured to be, in use, spaced at least 2.5 centimeters from the outer edge of the platen .