mhurhangee/patent-ind-claim-en huggingface dataset:
An in-vitro method for polyclonal stimulation of T cells comprising contacting a population of T cells with a humanized anti-CD3 antibody fragment, wherein said antibody fragment comprises a heavy chain variable domain comprising the sequence of SEQ ID NO: 16 , and a light chain variable domain comprising the sequence of SEQ ID NO: 17, and wherein said anti-CD3 antibody fragment is linked to particles.
An electrode assembly , comprising: an electrode body, wherein the electrode body is configured for dispensing a conductive fluid or gel from a reservoir; one or more tubular members extending from the electrode body and having a distal tip, at least some of the one or more tubular members having a tissue-contacting surface , a distribution channel formed within and extending along the tissue-contacting surface , and a lumen with a distal opening in the distal tip, wherein the one or more tubular members receive the conductive fluid or gel from the lumen so that the conductive fluid or gel may flow through the distribution channel over the patient tissue to form an electrically conductive path, wherein the fluid or gel is configured to enter each distribution channel directly from the lumen ; and means on the electrode body for dispensing the conductive fluid or gel from the reservoir through the lumen(s) and out of the distal opening(s) of the tubular member(s) ; wherein the electrode body defines a flow path for the conductive fluid or gel from the reservoir through the lumen(s) and out of the distal opening(s) of the tubular member . an electrode body, wherein the electrode body is configured for dispensing a conductive fluid or gel from a reservoir; one or more tubular members extending from the electrode body and having a distal tip, at least some of the one or more tubular members having a tissue-contacting surface , a distribution channel formed within and extending along the tissue-contacting surface , and a lumen with a distal opening in the distal tip, wherein the one or more tubular members receive the conductive fluid or gel from the lumen so that the conductive fluid or gel may flow through the distribution channel over the patient tissue to form an electrically conductive path, wherein the fluid or gel is configured to enter each distribution channel directly from the lumen ; and means on the electrode body for dispensing the conductive fluid or gel from the reservoir through the lumen(s) and out of the distal opening(s) of the tubular member(s) ; wherein the electrode body defines a flow path for the conductive fluid or gel from the reservoir through the lumen(s) and out of the distal opening(s) of the tubular member .
A process for preparing adipic acid, the process comprising reacting 1,6-hexanediol and oxygen in the presence of a catalyst comprising platinum on a support comprising zirconia or stabilized zirconia thereby producing a reaction mixture comprising adipic acid.
A transparency comprising: a plurality of sheets joined together to provide a laminated window having a vision area, the window having a moisture seal on the peripheral and marginal edge portions of the sheets; a moisture sensor positioned between the sheets and/or between the sheets and the moisture seal, wherein the moisture sensor comprises an electrolyte member between a first electrode and a second electrode wherein the electrolyte material is in ionic contact with the first and second electrodes and maintains the first and the second electrodes spaced from one another and out of surface contact with one another, and sensor electronics operatively connected to the electrodes of the sensor to measure a potential between the first and the second electrode and/or to measure the current through the sensor to determine amount of moisture absorbed by the electrolyte member, wherein the potential between the first and the second electrode and/or the current through the sensor measures the amount of moisture within the laminated window in the area of the moisture sensor. a plurality of sheets joined together to provide a laminated window having a vision area, the window having a moisture seal on the peripheral and marginal edge portions of the sheets; a moisture sensor positioned between the sheets and/or between the sheets and the moisture seal, wherein the moisture sensor comprises an electrolyte member between a first electrode and a second electrode wherein the electrolyte material is in ionic contact with the first and second electrodes and maintains the first and the second electrodes spaced from one another and out of surface contact with one another, and sensor electronics operatively connected to the electrodes of the sensor to measure a potential between the first and the second electrode and/or to measure the current through the sensor to determine amount of moisture absorbed by the electrolyte member, wherein the potential between the first and the second electrode and/or the current through the sensor measures the amount of moisture within the laminated window in the area of the moisture sensor.
A linear stepper motor comprising a rotor, two plain bearings (13, 15; 14, 16), two motor bearing shields , a spindle nut , and a fork-shaped actuating rod ; wherein the rotor comprises a rotor shaft that comprises a motive thread and is configured to drive a linearly guided actuator, the rotor shaft comprises plain bearing journals at ends thereof, which each comprise an end radially and axially enclosed in the plain bearings (13, 15; 14, 16) seated in the motor bearing shields , and, by the motive thread , axially drives the spindle nut connected with the fork-shaped actuating rod in a rotation-proof manner; characterised in that the rotor shaft comprises a flexurally and torsionally rigid plastic threaded spindle with a plastic core with coaxially arranged metallic shaft ends so as to act as metallic journals on opposite ends for concurrent plain bearing support and axial support.
A wind turbine rotor blade comprising • a blade tip , • a blade root for attachment to a rotor hub, the blade root defining a z-axis of a right-handed coordinate system, • an aerodynamic shell having a leading edge , a trailing edge , a pressure side , a suction side , and, at a longitudinal position close to the blade tip , an aerodynamic profile with a chord and a profile height , the chord defining a direction of a y-axis of the right-handed coordinate system and the profile height defining a direction of an x-axis of the right-handed coordinate system, and • a load carrying structure including a shear web connecting the pressure side and the suction side , wherein • the wind turbine rotor blade has a prebend towards the pressure side such that the blade tip is offset from the z-axis along the direction of the x-axi s, • the wind turbine rotor blade has a sweep towards the trailing edge such that the blade tip is offset from the z-axis along the direction of the y-axis, • the shear web is a planar shear web defining a shear web plane , and • the shear web plane comprises the z-axis or has a constant distance therefrom, characterized in that • the shear web plane is inclined with regard to the x-axis and • the shear web extends over a large part of a length of the wind turbine rotor blade , including a longitudinal section having the sweep and the prebend. • a blade tip , • a blade root for attachment to a rotor hub, the blade root defining a z-axis of a right-handed coordinate system, • an aerodynamic shell having a leading edge , a trailing edge , a pressure side , a suction side , and, at a longitudinal position close to the blade tip , an aerodynamic profile with a chord and a profile height , the chord defining a direction of a y-axis of the right-handed coordinate system and the profile height defining a direction of an x-axis of the right-handed coordinate system, and • a load carrying structure including a shear web connecting the pressure side and the suction side , wherein • the wind turbine rotor blade has a prebend towards the pressure side such that the blade tip is offset from the z-axis along the direction of the x-axi s, • the wind turbine rotor blade has a sweep towards the trailing edge such that the blade tip is offset from the z-axis along the direction of the y-axis, • the shear web is a planar shear web defining a shear web plane , and • the shear web plane comprises the z-axis or has a constant distance therefrom, characterized in that • the shear web plane is inclined with regard to the x-axis and • the shear web extends over a large part of a length of the wind turbine rotor blade , including a longitudinal section having the sweep and the prebend.
A method for manufacturing a piston housing, comprising: defining a piston housing design having a first fluid chamber design connected to a second fluid chamber design via a structural member design; manufacturing, by an additive manufacturing process, a piston housing (200;400;500) based on the piston housing design, the piston housing (230;330;430;530) comprising a first fluid chamber (230;330;430;530), manufactured based on the first fluid chamber design, in fluid communication with a second fluid chamber (230;330;430;530), manufactured based on the second fluid chamber design, via a structural member (420;520), manufactured based on the structural member design, wherein the structural member defines a non-linear fluid passage (220;320) between the first fluid chamber (230;330;430;530) and the second fluid chamber (230;330;430;530); and wherein the structural member includes a box beam (420-2) disposed between the first fluid chamber and the second fluid chamber, and a web disposed between the box beam and the non-linear fluid passage; wherein the additive manufacturing process includes at least one of fused deposition modeling, polyjet 3D printing, electron beam freeform fabrication, direct metal laser sintering, electron-beam melting, selective laser melting, selective heat sintering, selective laser sintering, stereolithography, multiphoton photopolymerization, and digital light processing.
An image capturing apparatus (M) comprising: a stage for supporting a sample (S); a stage control unit for moving the stage at a predetermined speed; a light source for outputting light; a light guiding optical system including a light dividing unit for dividing an optical image of the sample (S) into a first image for capturing an image and a second image for focus control; a first imaging unit for capturing the first image; a second imaging unit for capturing the second image; a focus control unit for analyzing the second image so as to control a focus position of the image pickup by the first imaging unit based on the analysis result; and an optical-path-difference changing unit for changing an optical path difference between the first image and the second image based on a predetermined target focus interval for capturing Z-stack images consisting of the first images at different layers in a depth direction of the sample (S), wherein the focus control unit is configured to control the focus position and the first imaging unit is configured to capture the first image during the movement of the stage by the stage control unit every time the optical path difference is changed by the optical-path-difference changing unit . a stage for supporting a sample (S); a stage control unit for moving the stage at a predetermined speed; a light source for outputting light; a light guiding optical system including a light dividing unit for dividing an optical image of the sample (S) into a first image for capturing an image and a second image for focus control; a first imaging unit for capturing the first image; a second imaging unit for capturing the second image; a focus control unit for analyzing the second image so as to control a focus position of the image pickup by the first imaging unit based on the analysis result; and an optical-path-difference changing unit for changing an optical path difference between the first image and the second image based on a predetermined target focus interval for capturing Z-stack images consisting of the first images at different layers in a depth direction of the sample (S), wherein the focus control unit is configured to control the focus position and the first imaging unit is configured to capture the first image during the movement of the stage by the stage control unit every time the optical path difference is changed by the optical-path-difference changing unit .
A braking and/or clamping device for a shaft which is guided relative to a main body , having an actuating assembly and a shaft coupling assembly , - wherein the actuating assembly has a split housing , which has an attachment zone and a bending zone which can bulge elastically in some regions and has two bending plates spaced by a pressure space , - wherein the bending plates each have jaws in two mutually opposing clamping zones , said jaws having friction faces with surface normals pointing inwards, - wherein there is a sealed pressure space between the bending plates and at least one supporting element , which sealed pressure space can be filled with a pressure medium in order to push the friction faces apart elastically, - wherein the shaft coupling assembly has a coupling region which has two mutually spaced friction faces with surface normals pointing outwards, - wherein the shaft coupling assembly has a flange region via which it is arranged on the shaft either directly or indirectly via a clamping mechanism, and - wherein, when the pressure space is relieved of load, the friction faces of the actuating assembly are applied to the friction faces of the shaft coupling assembly , providing the clamping and/or braking force, characterised in that - at least one deformation measurement means is arranged in the transition region between the attachment zone and the bending zone , - each bending plate has an axial groove from the pressure space in order to support at least one supporting element , and - the shaft coupling assembly has a slotted or multiply split ring as the brake disc . - wherein the actuating assembly has a split housing , which has an attachment zone and a bending zone which can bulge elastically in some regions and has two bending plates spaced by a pressure space , - wherein the bending plates each have jaws in two mutually opposing clamping zones , said jaws having friction faces with surface normals pointing inwards, - wherein there is a sealed pressure space between the bending plates and at least one supporting element , which sealed pressure space can be filled with a pressure medium in order to push the friction faces apart elastically, - wherein the shaft coupling assembly has a coupling region which has two mutually spaced friction faces with surface normals pointing outwards, - wherein the shaft coupling assembly has a flange region via which it is arranged on the shaft either directly or indirectly via a clamping mechanism, and - wherein, when the pressure space is relieved of load, the friction faces of the actuating assembly are applied to the friction faces of the shaft coupling assembly , providing the clamping and/or braking force, characterised in that - at least one deformation measurement means is arranged in the transition region between the attachment zone and the bending zone , - each bending plate has an axial groove from the pressure space in order to support at least one supporting element , and - the shaft coupling assembly has a slotted or multiply split ring as the brake disc .
A method of identifying a plurality of target-reactive T-cell receptors (TCRs) from a population of cells expressing a plurality TCRs, comprising: (a) providing a population of cells expressing a plurality of TCRs, each cell of the population of cells expressing a TCR of the plurality of TCRs, wherein the plurality of TCRs comprises at least 50 different cognate pairs and comprises V regions from a plurality of V genes, and wherein the plurality of TCRs is exogenous to the population of cells; (b) contacting the population of cells expressing a plurality TCRs from (a) with one or more target antigens in complex with a major histocompatibility complex (MHC) molecule, wherein a subset of the population of cells express a plurality of target reactive TCRs that bind to the one or more target antigens in complex with the MHC molecule; and (c) identifying at least two cells of the subset of the population of cells that express the plurality of target-reactive TCRs from (b) which express at least two target-reactive TCRs of the plurality of target-reactive TCRs, thereby identifying the at least two target-reactive TCRs of the plurality of target-reactive TCRs. (a) providing a population of cells expressing a plurality of TCRs, each cell of the population of cells expressing a TCR of the plurality of TCRs, wherein the plurality of TCRs comprises at least 50 different cognate pairs and comprises V regions from a plurality of V genes, and wherein the plurality of TCRs is exogenous to the population of cells; (b) contacting the population of cells expressing a plurality TCRs from (a) with one or more target antigens in complex with a major histocompatibility complex (MHC) molecule, wherein a subset of the population of cells express a plurality of target reactive TCRs that bind to the one or more target antigens in complex with the MHC molecule; and (c) identifying at least two cells of the subset of the population of cells that express the plurality of target-reactive TCRs from (b) which express at least two target-reactive TCRs of the plurality of target-reactive TCRs, thereby identifying the at least two target-reactive TCRs of the plurality of target-reactive TCRs.
A method comprising: i) controlling a set of transducers to create an acoustic field exhibiting desired amplitude at a plurality of control points so as to generate haptic feedback in midair; ii) encoding a dominant eigenvector of an eigensystem that describes an effect that one control point of given phase and amplitude has on other control points of given phases and amplitudes to approximate a basis vector of a set of linear modifications that have different overall effects on constructive and destructive interference across the control points; and characterized by , iii) creating a synchronized pseudo-random binary sequence that only requires communication between the transducers to initialize and synchronize; and, iv) once initialized, applying a pseudorandom phase walk approach to each control point, whereby transducers contributing to the same control point produce the same pseudo-random phase walk, so as to reduce communication between the transducers to be able to contribute to the same control point in the acoustic field. i) controlling a set of transducers to create an acoustic field exhibiting desired amplitude at a plurality of control points so as to generate haptic feedback in midair; ii) encoding a dominant eigenvector of an eigensystem that describes an effect that one control point of given phase and amplitude has on other control points of given phases and amplitudes to approximate a basis vector of a set of linear modifications that have different overall effects on constructive and destructive interference across the control points; and characterized by , iii) creating a synchronized pseudo-random binary sequence that only requires communication between the transducers to initialize and synchronize; and, iv) once initialized, applying a pseudorandom phase walk approach to each control point, whereby transducers contributing to the same control point produce the same pseudo-random phase walk, so as to reduce communication between the transducers to be able to contribute to the same control point in the acoustic field.
A process for producing an aluminum-alloyed and/or aluminum-containing zinc coating on an iron-based component, wherein the process comprises the following process steps in the order listed below: (a) increasing and/or adjusting the surface roughness of at least one surface of the iron-based component by mechanical treatment by means of an abrasive process, the increase and/or adjustment of the surface roughness being carried out in such a way that the surface has a mean (average) roughness Ra according to DIN EN ISO 4288:1998-04 in the range from 0.3 to 15 μm; then (b) hot-dip galvanizing the iron-based component in an aluminum-alloyed and/or aluminum-containing zinc melt, the zinc melt containing at least 0.1% by weight of aluminum, based on the zinc melt, wherein, after carrying out process step (b), an iron-based component provided with the aluminum-alloyed and/or aluminum-containing zinc layer and/or coated and/or covered is obtained with a zinc layer thickness in the range from 3 to 30 μm. (a) increasing and/or adjusting the surface roughness of at least one surface of the iron-based component by mechanical treatment by means of an abrasive process, the increase and/or adjustment of the surface roughness being carried out in such a way that the surface has a mean (average) roughness Ra according to DIN EN ISO 4288:1998-04 in the range from 0.3 to 15 μm; then (b) hot-dip galvanizing the iron-based component in an aluminum-alloyed and/or aluminum-containing zinc melt, the zinc melt containing at least 0.1% by weight of aluminum, based on the zinc melt,
A floor drain kit, comprising a floor drain comprising a drain bowl , wherein an adapted through hole in the bottom of the drain bowl enables the drain bowl to be guided over an open upper end of a drainpipe protruding upwards from inside a floor, wherein a ring shaped sealing around the circumference of the through hole in the bottom of the drain bowl is arranged providing a water tight sliding fit around an outer surface of the drain pipe when the drain pipe is located inside the through hole in the bottom of the drain bowl , the floor drain kit characterised by further comprising an installation cover for covering the upper opening of the drain bowl , wherein a through hole in the installation cover is adapted to a diameter of the drainpipe ; at least two upwardly protruding patches are attached in one end to an upper surface of the installation cover adjacent to the through hole in the installation cover ; a fastening strip is attachable around the drainpipe and the protruding patches , thereby locking the drain bowl firmly to the drainpipe while the drain bowl is being installed at a defined height relative to the floor. floor drain comprising a drain bowl , wherein an adapted through hole in the bottom of the drain bowl enables the drain bowl to be guided over an open upper end of a drainpipe protruding upwards from inside a floor, wherein a ring shaped sealing around the circumference of the through hole in the bottom of the drain bowl is arranged providing a water tight sliding fit around an outer surface of the drain pipe when the drain pipe is located inside the through hole in the bottom of the drain bowl , the floor drain kit characterised by further comprising an installation cover for covering the upper opening of the drain bowl , wherein a through hole in the installation cover is adapted to a diameter of the drainpipe ; at least two upwardly protruding patches are attached in one end to an upper surface of the installation cover adjacent to the through hole in the installation cover ; a fastening strip is attachable around the drainpipe and the protruding patches , thereby locking the drain bowl firmly to the drainpipe while the drain bowl is being installed at a defined height relative to the floor.