A system for navigating to a target , the system comprising: a therapeutic material application tool having a distal tip; an extended working channel defining a lumen extending therethrough for receiving a therapeutic material application tool; a computing device including a memory and at least one processor ; a tracking system for tracking the progression of the extended working channel through an airway; a plurality of images of the airway stored in the memory; a display device that displays a user interface ; and a program stored in the memory that, when executed by the at least one processor, presents the user interface, the user interface including: at least one image of the plurality of images depicting the target and a progression of the extended working channel through the airway; and a probability treatment zone defining a maximum probable distribution of a therapeutic medication distributed by the therapeutic material application tool once deployed beyond an opening of the extended working channel displayed in the at least one image, wherein the therapeutic material application tool is configured such that therapeutic medication exits the distal tip of the therapeutic material application tool in a three-dimensional volumetric cone shape followed by forming a volumetric spherical shape as the therapeutic medication continues to be dispersed; and wherein the maximum probable distribution represents a volumetric shape having a cone shape projection with a spherical cap emanating from a center point of a distal tip of the extended working channel, the volumetric shape corresponding to the maximum volume for which the therapeutic medication is therapeutically effective. a therapeutic material application tool having a distal tip; an extended working channel defining a lumen extending therethrough for receiving a therapeutic material application tool; a computing device including a memory and at least one processor ; a tracking system for tracking the progression of the extended working channel through an airway; a plurality of images of the airway stored in the memory; a display device that displays a user interface ; and a program stored in the memory that, when executed by the at least one processor, presents the user interface, the user interface including: at least one image of the plurality of images depicting the target and a progression of the extended working channel through the airway; and a probability treatment zone defining a maximum probable distribution of a therapeutic medication distributed by the therapeutic material application tool once deployed beyond an opening of the extended working channel displayed in the at least one image, at least one image of the plurality of images depicting the target and a progression of the extended working channel through the airway; and a probability treatment zone defining a maximum probable distribution of a therapeutic medication distributed by the therapeutic material application tool once deployed beyond an opening of the extended working channel displayed in the at least one image, wherein the therapeutic material application tool is configured such that therapeutic medication exits the distal tip of the therapeutic material application tool in a three-dimensional volumetric cone shape followed by forming a volumetric spherical shape as the therapeutic medication continues to be dispersed; and wherein the maximum probable distribution represents a volumetric shape having a cone shape projection with a spherical cap emanating from a center point of a distal tip of the extended working channel, the volumetric shape corresponding to the maximum volume for which the therapeutic medication is therapeutically effective. <EOS>