mhurhangee/patent-ind-claim-en huggingface dataset:
A polypeptide comprising a fibronectin type III tenth domain ( 10 Fn3) wherein the 10 Fn3 domain comprises a) AB, BC, CD, DE, EF, and FG loops, b) a CD loop comprising an amino acid sequence according to the formula G-X 1 -X 2 -V-X 3 -X 4 -X 5 -S-X 6 -X 7 -G-X 8 -X 9 -Y-X 10 -X 11 -X 12 -E (SEQ ID NO: 170), wherein, (a) X 1 is selected from the group consisting of R or W; (b) X 2 is selected from the group consisting of H, E, D, Y, or Q; (c) X 3 is selected from the group consisting of Q or H; (d) X 4 is selected from the group consisting of I, K, M, Q, L, or V; (e) X 5 is selected from the group consisting of Y, F, or N; (f) X 6 is selected from the group consisting of D, V, or E; (g) X 7 is selected from the group consisting of L, W, or F; (h) X 8 is selected from the group consisting of P or T; (i) X 9 is selected from the group consisting of L or M; (j) X 10 is selected from the group consisting of I or V; (k) X 11 is selected from the group consisting of Y or F; and (l) X 12 is selected from the group consisting of T, S, Q, N, or A, c) wherein the polypeptide binds to human serum albumin with a K D of less than 500 nM, and d) wherein the 10 Fn3 domain further binds to one or more of rhesus serum albumin, cynomolgus serum albumin, mouse serum albumin, and rat serum albumin with a K D of less than 500 nM, for example, less than 100 nM, or less than 10 nM (a) X 1 is selected from the group consisting of R or W; (b) X 2 is selected from the group consisting of H, E, D, Y, or Q; (c) X 3 is selected from the group consisting of Q or H; (d) X 4 is selected from the group consisting of I, K, M, Q, L, or V; (e) X 5 is selected from the group consisting of Y, F, or N; (f) X 6 is selected from the group consisting of D, V, or E; (g) X 7 is selected from the group consisting of L, W, or F; (h) X 8 is selected from the group consisting of P or T; (i) X 9 is selected from the group consisting of L or M; (j) X 10 is selected from the group consisting of I or V; (k) X 11 is selected from the group consisting of Y or F; and (l) X 12 is selected from the group consisting of T, S, Q, N, or A,
An orthopaedic prosthetic component , comprising: a base , a fixation peg extending away from the base to a distal tip , the fixation peg including a porous three-dimensional structure configured to permit bone in-growth, the porous three-dimensional structure having an outer surface boundary , wherein the fixation peg includes a plurality of plates attached to the porous three-dimensional structure at the outer surface boundary , each plate including a tapered body having an outer wall that faces away from the porous three-dimensional structure and is devoid of any openings; wherein the tapered body of each plate extends longitudinally along the porous three-dimensional structure ; wherein the outer wall of each plate includes a concave surface that defines a tapered channel . a base , a fixation peg extending away from the base to a distal tip , the fixation peg including a porous three-dimensional structure configured to permit bone in-growth, the porous three-dimensional structure having an outer surface boundary , wherein the fixation peg includes a plurality of plates attached to the porous three-dimensional structure at the outer surface boundary , each plate including a tapered body having an outer wall that faces away from the porous three-dimensional structure and is devoid of any openings; wherein the tapered body of each plate extends longitudinally along the porous three-dimensional structure ; wherein the outer wall of each plate includes a concave surface that defines a tapered channel .
A separation device for a spacecraft or launcher, the separation device comprising an inner housing divided into at least two portions locked to each other by a locking device in a locking position and thereby hindering the at least two portions from separating, the locking device is engaging the inner housing by locking means and is arranged to move between a locking position and a releasing position, the separation device comprising an initiator comprising means for providing high pressure fluid to an expansion chamber when the separation device is switched from a locked state to a released state, wherein the high pressure fluid in the expansion chamber moves the locking device from the locking position to the releasing position when the separation device is switched from the locked state to the released state, characterized in that the separation device comprises a dampening arrangement arranged to attenuate a peak load when the separation device is switched from the locked state to the released state, wherein the dampening arrangement comprises a dampening plate in an end position in connection to the releasing position, wherein the dampening arrangement comprises at least one dampening pin arranged between the locking device and the dampening plate , wherein the dampening pin is arranged to hit and plastically deform the dampening plate during movement of the locking device from the locking position to the releasing position for absorbing energy from the locking device which attenuates the peak load.
An aerosol generating device, comprising an aerosol generator including: a container having a liquid chamber , an aerosol chamber , and an insertion slot for a plug , the insertion slot defines an insertion direction (S); and an atomizing module assembled in the container , wherein the liquid chamber and the aerosol chamber are respectively arranged at two opposite sides of the atomizing module , and are in spatial communication with each other through the atomizing module , and wherein the atomizing module includes two electrode regions having the same polarity and being electrically connected to each other, characterized in that , the two electrode regions are located on a plane, the plane and the insertion direction (S) of the insertion slot have an acute angle (σ) therebetween, and a central axis (C2) of the aerosol chamber is substantially perpendicular to the plane. a container having a liquid chamber , an aerosol chamber , and an insertion slot for a plug , the insertion slot defines an insertion direction (S); and an atomizing module assembled in the container , wherein the liquid chamber and the aerosol chamber are respectively arranged at two opposite sides of the atomizing module , and are in spatial communication with each other through the atomizing module , and wherein the atomizing module includes two electrode regions having the same polarity and being electrically connected to each other, characterized in that , the two electrode regions are located on a plane, the plane and the insertion direction (S) of the insertion slot have an acute angle (σ) therebetween, and a central axis (C2) of the aerosol chamber is substantially perpendicular to the plane.
A device for mounting a retaining clip on a line element , having clamping device for clamping the retaining clip and alignment of the retaining clip with respect to the line element , having a bundling head for guiding a band connected or connectable to the retaining clip around the line element , wherein the clamping device has a disc element with a centric recess for the line element , characterized in that the clamping device has two disc elements with a centric recess for the line element , which disc elements are arranged in parallel and can be rotated against each other about a common axis of rotation, and that the disc elements in each case have a clamping jaw for holding the retaining clip between the clamping jaws , wherein the disc elements can be rotated against each other, in order to move the clamping jaws towards or away from each other.
A strut-holding clip , comprising: an end wall ; a first leg and a second leg extending from the end wall , the first leg and the second leg configured to straddle the gear selection strut ; a first prong configured to flex within the first leg ; a second prong configured to flex within the second leg ; characterized in that the end wall is configured to block a gear selection strut from travelling; the first prong terminates in a first barb; the second prong terminates in a second barb ; the strut-holding clip further comprising: a first foot angled with respect to the first leg and configured to elastically oppose the first barb; and a second foot angled with respect to the second leg and configured to elastically oppose the second barb . an end wall ; a first leg and a second leg extending from the end wall , the first leg and the second leg configured to straddle the gear selection strut ; a first prong configured to flex within the first leg ; a second prong configured to flex within the second leg ; characterized in that the end wall is configured to block a gear selection strut from travelling; the first prong terminates in a first barb; the second prong terminates in a second barb ; the strut-holding clip further comprising: a first foot angled with respect to the first leg and configured to elastically oppose the first barb; and a second foot angled with respect to the second leg and configured to elastically oppose the second barb . a first foot angled with respect to the first leg and configured to elastically oppose the first barb; and a second foot angled with respect to the second leg and configured to elastically oppose the second barb .
A belt for suspending and/or driving an elevator car , comprising: a plurality of tension elements extending longitudinally along a length of the belt ; a plurality of fibers interlaced with the plurality of tension elements forming a composite belt structure; and a coating at least partially encapsulating the composite belt structure to improve two or more operational characteristics of the belt , characterised in that the coating comprises a base material and one or more additives . a plurality of tension elements extending longitudinally along a length of the belt ; a plurality of fibers interlaced with the plurality of tension elements forming a composite belt structure; and a coating at least partially encapsulating the composite belt structure to improve two or more operational characteristics of the belt ,
An installation member for a vehicle configured to be supported at a fixing member fixed to a vehicle body side, wherein a central axis extends from an upper side of the installation member to a lower side of the installation member when the installation member is mounted on a vehicle, said installation member comprising: an irradiating device , which is installed inside the installation member , including: an emitter that is disposed at the central axis and that emits light toward the lower side; and an irradiating body that is disposed at the lower side of the emitter , and at which a reflecting face and an irradiating face are provided, wherein the reflecting face surrounds the emitter and reflects light emitted by the emitter toward the central axis, wherein the irradiating face irradiates light reflected by the reflecting face toward the lower side of the installation member and is concave toward the upper side of the installation member , characterised in that an irradiating aperture which exposes the inside of the installation member to the lower side of the installation member is formed passing through a lower wall of the installation member , the light irradiated to the lower side from the irradiating face passing through the irradiating aperture , the irradiating aperture having a diameter that increases on progression toward the lower side, and in that the area of the inside of the concave irradiating face is in communication with the irradiating aperture and a lower end portion of the irradiating face is flush with a peripheral face of the irradiating aperture . an irradiating device , which is installed inside the installation member , including: an emitter that is disposed at the central axis and that emits light toward the lower side; and an irradiating body that is disposed at the lower side of the emitter , and at which a reflecting face and an irradiating face are provided, wherein the reflecting face surrounds an emitter that is disposed at the central axis and that emits light toward the lower side; and an irradiating body that is disposed at the lower side of the emitter , and at which a reflecting face and an irradiating face are provided, wherein the reflecting face surrounds the emitter and reflects light emitted by the emitter toward the central axis, wherein the irradiating face irradiates light reflected by the reflecting face toward the lower side of the installation member and is concave toward the upper side of the installation member , characterised in that an irradiating aperture which exposes the inside of the installation member to the lower side of the installation member is formed passing through a lower wall of the installation member , the light irradiated to the lower side from the irradiating face passing through the irradiating aperture , the irradiating aperture having a diameter that increases on progression toward the lower side, and in that the area of the inside of the concave irradiating face is in communication with the irradiating aperture and a lower end portion of the irradiating face is flush with a peripheral face of the irradiating aperture .
An electrosurgical wave generator , wherein when the electrosurgical wave generator is electrically coupled to an electrode to form an electrosurgical system: the wave generator is adapted to sense various parameters of the electrosurgical system and automatically adjust the level of electrical energy being transmitted from the electrode to the patient tissue based upon a customized power curve stored in the wave generator, the customized power curve being such that during an electrosurgical procedure, power to the electrode is rapidly increased up to a pre-determined tissue impedance level, and then as tissue impedance increases above the pre-determined tissue impedance level, the power to the electrode is rapidly reduced in inverse proportion to further increases in tissue impedance.
A positive electrode for a nonaqueous electrolyte battery comprising a positive electrode current collector and a positive electrode material layer that is formed on the positive electrode current collector and contains an active material, wherein, when the positive electrode material layer is subjected to pyrolysis GC/MS measurement under a temperature rise condition of 5°C/min, an area C1 (mL/g) of a first region having a peak top in a range of 100°C or more and less than 500°C and an area C2 (mL/g) of a second region having a peak top in a range of 500°C or more and 600°C or less satisfy a following Formula : 6 ≤ C 1 / C 2 ≤ 10 the positive electrode comprising, in a pore distribution curve attained by a mercury intrusion method, a first peak (PA) corresponding to a mode diameter appearing in a range where a pore diameter is 0.1 um or more and less than 0.3 um and a second peak (PB) corresponding to a mode diameter appearing in a range where a pore diameter is 0.3 um or more and 1 μm or less, and when pore volumes at peak tops of the peak (PA) and the peak (PB) are denoted as P1 [ml/g] and P2 [ml/g], respectively, these satisfy a following Formula : 0.60 ≤ P 1 / P 1 + P 2 ≤ 0.9 and when a pore volume V1 [ml/g] of pores having a pore diameter of 0.1 um or more and 1.0 um or less and a total pore volume V [ml/g], these satisfy a following Formula : 0.45 ≤ V 1 / V ≤ 0.7 the pore volume V1 [ml/g] is in a range of 0.057 ml/g to 0.071 ml/g, and the positive electrode material layer further contains a binder in an amount of 0.1 parts by weight or more and 4 parts by weight or less with respect to 100 parts by weight of the active material. when the positive electrode material layer is subjected to pyrolysis GC/MS measurement under a temperature rise condition of 5°C/min, an area C1 (mL/g) of a first region having a peak top in a range of 100°C or more and less than 500°C and an area C2 (mL/g) of a second region having a peak top in a range of 500°C or more and 600°C or less satisfy a following Formula : 6 ≤ C 1 / C 2 ≤ 10 the positive electrode comprising, in a pore distribution curve attained by a mercury intrusion method, a first peak (PA) corresponding to a mode diameter appearing in a range where a pore diameter is 0.1 um or more and less than 0.3 um and a second peak (PB) corresponding to a mode diameter appearing in a range where a pore diameter is 0.3 um or more and 1 μm or less, and when pore volumes at peak tops of the peak (PA) and the peak (PB) are denoted as P1 [ml/g] and P2 [ml/g], respectively, these satisfy a following Formula : 0.60 ≤ P 1 / P 1 + P 2 ≤ 0.9 and when a pore volume V1 [ml/g] of pores having a pore diameter of 0.1 um or more and 1.0 um or less and a total pore volume V [ml/g], these satisfy a following Formula : 0.45 ≤ V 1 / V ≤ 0.7 the pore volume V1 [ml/g] is in a range of 0.057 ml/g to 0.071 ml/g, and the positive electrode material layer further contains a binder in an amount of 0.1 parts by weight or more and 4 parts by weight or less with respect to 100 parts by weight of the active material.
Vehicle consisting of a rear frame having two side beams oriented in the longitudinal direction of the vehicle and connected with each other by at least two ties distributed in the longitudinal direction of the vehicle , the two backmost ties connected by a central beam , and the space defined by the crossings its and side beams being closed in part by a lower floor , the vehicle being characterized in that it also includes an absorption device placed between the center beam and the lower floor and comprising at least one absorber .
A system for creating a synthetic computed-tomography, CT, image volume, comprising: an affine registration module configured to register a first clinical image volume to each of a plurality of candidate CT image volumes and thereby obtain a plurality of corresponding candidate similarity metrics, and to register a reference CT image volume to a first clinical image volume and thereby produce a first registration, where the first clinical image volume is a magnetic resonance, MR, scan, a MR data portion of a positron emission tomography-MR, PET-MR, scan or a MR data portion of a single-proton emission tomography-MR, SPECT-MR, scan; a selection tool configured to select said reference CT image volume from among said plurality of candidate CT image volumes based on a comparison of each of said plurality of corresponding candidate similarity metrics to a desired similarity metric; a smoothing module configured to further refine said first registration and thereby produce a smoothed registration; a voxelwise intensity module configured to further refine said smoothed registration and thereby produce a synthetic CT image volume having characteristics correlated to those of said first clinical image volume ; a synthetic CT engine configured to derive a map of attenuation coefficients based on said synthetic CT image volume ; and an attenuation correction engine configured to correct the attenuation in a second clinical image volume based on said map, where the second clinical image volume is a PET scan, a PET data portion of the PET-MR scan, or a PET data portion of the SPECT-MR scan. an affine registration module configured to register a first clinical image volume to each of a plurality of candidate CT image volumes and thereby obtain a plurality of corresponding candidate similarity metrics, and to register a reference CT image volume to a first clinical image volume and thereby produce a first registration, where the first clinical image volume is a magnetic resonance, MR, scan, a MR data portion of a positron emission tomography-MR, PET-MR, scan or a MR data portion of a single-proton emission tomography-MR, SPECT-MR, scan; a selection tool configured to select said reference CT image volume from among said plurality of candidate CT image volumes based on a comparison of each of said plurality of corresponding candidate similarity metrics to a desired similarity metric; a smoothing module configured to further refine said first registration and thereby produce a smoothed registration; a voxelwise intensity module configured to further refine said smoothed registration and thereby produce a synthetic CT image volume having characteristics correlated to those of said first clinical image volume ; a synthetic CT engine configured to derive a map of attenuation coefficients based on said synthetic CT image volume ; and an attenuation correction engine configured to correct the attenuation in a second clinical image volume based on said map, where the second clinical image volume is a PET scan, a PET data portion of the PET-MR scan, or a PET data portion of the SPECT-MR scan.
A locking cylinder for an electronic key , having a core movable in a housing , having a locking channel arranged in the core for introducing the key and an antenna arranged in the housing for detecting electronic signals of the key and having an electronic blocking device for selectively blocking or releasing the movement of the core depending on the signals of the key , wherein electrical contacts are arranged in the core for making contact with corresponding contacts on the key , which electrical contacts of the core are connected via electrical conductors to a transmission antenna arranged in the core for transmitting the signals of the key to the antenna in the housing and the transmission antenna in the core and the antenna in the housing have coils , characterized in that the coils of the transmission antenna in the core and of the antenna in the housing are arranged concentrically to one another.