mhurhangee/patent-ind-claim-en huggingface dataset:
Method for transfer of containers , such as vials, between a freeze dryer that is located at a first location and a separate transport vehicle that is mobile with respect to the freeze dryer, wherein the freeze dryer comprises a freeze dryer housing with an access opening towards an inner freeze drying chamber inside the freeze dryer housing, multiple shelves (21-24) that are arranged spaced apart above each other inside the freeze dryer chamber and each provided with a horizontally extending first flat supporting surface for supporting the containers, wherein the mobile transport vehicle comprises a mobile undercarriage supporting a storage housing with an access opening towards an inner storage chamber , a carrier provided with a second flat supporting surface for supporting the containers inside the storage housing, and a container shifter , wherein the container shifter comprises a container pushing shovel for pushing out containers away from the second flat supporting surface in a pushing out direction (G, H) parallel to the second flat supporting surface, and a container pulling shovel that is moveable in the pulling in direction (J,K) parallel to the second flat support surface and opposite to the pushing out direction (G, H), and that is moveable in a direction transverse to the pulling in direction (J, k) between a passing over position in which the container pulling shovel passes freely over a first or second container pack in an extending direction opposite the pulling in direction and a lower shovel position in which the container pulling shovel engages a side of the first or second container pack in the pulling in direction, wherein the method comprises for a first shelf aligning the carrier and the shelf and by means of the pushing shovel pushing out (G) the first container pack of multiple mutually abutting containers from the second flat supporting surface onto the first flat supporting surface of the first shelf, reversing the pushing shovel and subsequently pushing out (H) the second container pack of multiple mutually abutting containers from the second flat supporting surface onto the first flat supporting surface of the first shelf while leaving an elongated separation space free between the first container pack and the second container pack on the first shelf , wherein the width of the elongated separation space is sufficient for free movement of the container pulling shovel therein, and the method comprises moving the container pulling shovel in its passing over position in the extending direction towards and past the side of the first or second container pack, moving the container pulling shovel in the shovel position and moving the container pulling shovel in the pulling in direction for engagement of the side of the first or second container pack, and pulling in the container pack along the first flat support surface.
Connector suitable for being fitted on a shield wall , the connector comprising - a sleeve made of electrically insulating plastic material and having a wall with an inner surface and an outer surface , the sleeve being moulded in a single piece with a support , - a shield contact ring made of electrically conductive material, fitted in the sleeve , the shield contact ring being formed by a section of metal strip wound around a longitudinal axis parallel to that of the sleeve in which it is fitted and having ∘ an inner portion parallel to the longitudinal axis of the sleeve and located inside the sleeve , bearing on a first section of the inner surface of the wall of the sleeve , and intended to be in electrical contact with a ferrule placed around the shielding sheath of an electrical cable ; ∘ an outer portion located outside the sleeve , made in one piece with the inner portion and intended to be linked electrically to a shield wall , - characterized by the fact that the outer portion extends the inner portion , through at least one opening formed in the wall of the sleeve , parallel to the longitudinal axis of the sleeve . - a sleeve made of electrically insulating plastic material and having a wall with an inner surface and an outer surface , the sleeve being moulded in a single piece with a support , - a shield contact ring made of electrically conductive material, fitted in the sleeve , the shield contact ring being formed by a section of metal strip wound around a longitudinal axis parallel to that of the sleeve in which it is fitted and having ∘ an inner portion parallel to the longitudinal axis of the sleeve and located inside the sleeve , bearing on a first section of the inner surface of the wall of the sleeve , and intended to be in electrical contact with a ferrule placed around the shielding sheath of an electrical cable ; ∘ an outer portion located outside the sleeve , made in one piece with the inner portion and intended to be linked electrically to a shield wall , ∘ an inner portion parallel to the longitudinal axis of the sleeve and located inside the sleeve , bearing on a first section of the inner surface of the wall of the sleeve , and intended to be in electrical contact with a ferrule placed around the shielding sheath of an electrical cable ; ∘ an outer portion located outside the sleeve , made in one piece with the inner portion and intended to be linked electrically to a shield wall , - characterized by the fact that the outer portion extends the inner portion , through at least one opening formed in the wall of the sleeve , parallel to the longitudinal axis of the sleeve .
A method for constructing a next-generation sequencing DNA library for detecting DNA low-frequency mutations, comprising: step A: end-repairing DNA fragments to be sequenced in a sample containing low-frequency mutant DNA to obtain blunt-end DNA fragments; step B: A-tailing of a 3' end to the blunt-end DNA fragments to obtain DNA fragments with A-tail at the 3' end; step C: adding adapters to the DNA fragments with A-tail to the 3' end to obtain adapter-added DNA fragments; and step D: subjecting the adapter-added DNA fragments to PCR amplification to obtain amplification products, wherein in said step C, annealing products of a single-stranded DNA having a nucleotide sequence of SEQ ID NO: 1 and a single-stranded DNA having a nucleotide sequence of SEQ ID NO: 2 are used as the adapter; in said step D, a single-stranded DNA having a nucleotide sequence of SEQ ID NO: 3 is used as a PCR amplification primer; and the PCR amplification is conducted only once in step D in this method. step A: end-repairing DNA fragments to be sequenced in a sample containing low-frequency mutant DNA to obtain blunt-end DNA fragments; step B: A-tailing of a 3' end to the blunt-end DNA fragments to obtain DNA fragments with A-tail at the 3' end; step C: adding adapters to the DNA fragments with A-tail to the 3' end to obtain adapter-added DNA fragments; and step D: subjecting the adapter-added DNA fragments to PCR amplification to obtain amplification products, wherein in said step C, annealing products of a single-stranded DNA having a nucleotide sequence of SEQ ID NO: 1 and a single-stranded DNA having a nucleotide sequence of SEQ ID NO: 2 are used as the adapter; in said step D, a single-stranded DNA having a nucleotide sequence of SEQ ID NO: 3 is used as a PCR amplification primer; and the PCR amplification is conducted only once in step D in this method.
A Streptomyces avermitilis strain C63-51, deposited on December 22, 2016 in the China General Microbiological Culture Collection Center (CGMCC) with an accession number CGMCC NO. 13370.
A method of updating firmware in a plurality of endpoints configured as an advanced metering infrastructure "AMI" network configured for automated meter reading "AMR", the method comprising: sending, by a data collector , an announcement of a firmware update to the plurality of endpoints, wherein sending the announcement of the update comprises: unicasting the announcement to each endpoint from among the plurality of endpoints; wherein the announcement tells each respective endpoint when to receive the firmware update; broadcasting, by the data collector, the firmware update to the plurality of endpoints according to the announcement; receiving, at the data collector, indications of missing blocks from at least one endpoint of the plurality of endpoints that did not successfully receive all blocks of the broadcast firmware update; and sending, by the data collector, missing blocks to the at least one endpoint that did not successfully receive all blocks of the broadcast firmware update according to the indications, wherein sending the missing blocks to the at least one endpoint comprises selecting between a first transmission type and a second transmission type, based on how many of the plurality of endpoints are missing the missing blocks, wherein the first transmission type comprises unicasting, and the second transmission type comprises one of broadcasting and multicasting. sending, by a data collector , an announcement of a firmware update to the plurality of endpoints, wherein sending the announcement of the update comprises: unicasting the announcement to each endpoint from among the plurality of endpoints; wherein the announcement tells each respective endpoint when to receive the firmware update; unicasting the announcement to each endpoint from among the plurality of endpoints; wherein the announcement tells each respective endpoint when to receive the firmware update; broadcasting, by the data collector, the firmware update to the plurality of endpoints according to the announcement; receiving, at the data collector, indications of missing blocks from at least one endpoint of the plurality of endpoints that did not successfully receive all blocks of the broadcast firmware update; and sending, by the data collector, missing blocks to the at least one endpoint that did not successfully receive all blocks of the broadcast firmware update according to the indications, wherein sending the missing blocks to the at least one endpoint comprises selecting between a first transmission type and a second transmission type, based on how many of the plurality of endpoints are missing the missing blocks, wherein the first transmission type comprises unicasting, and the second transmission type comprises one of broadcasting and multicasting.
A fastener cartridge for use with a fastening instrument to fasten tissue, said fastener cartridge comprising: a cartridge body , including: a deck ; a plurality of fastener cavities ; and a member cavity ; fasteners removably stored in said fastener cavities , wherein said fasteners are deployable from said fastener cavities during a firing stroke of the fastening instrument , and wherein said fasteners are not stored in said member cavity ; and a deployable tissue flow control member movably positioned in said member cavity , wherein said tissue flow control member is movable between an undeployed position and a deployed position to engage the tissue during the firing stroke of the fastening instrument , wherein said fastener cartridge further comprises a sled configured to eject said fasteners from said cartridge body during the firing stroke of the fastening instrument , wherein said sled is also configured to deploy said tissue flow control member during the firing stoke of the fastening instrument characterized in that the deployable tissue flow control member is deployed to grip a portion of tissue in advance of the tissue portion being fastened. a cartridge body , including: a deck ; a plurality of fastener cavities ; and a member cavity ; a deck ; a plurality of fastener cavities ; and a member cavity ; fasteners removably stored in said fastener cavities , wherein said fasteners are deployable from said fastener cavities during a firing stroke of the fastening instrument , and wherein said fasteners are not stored in said member cavity ; and a deployable tissue flow control member movably positioned in said member cavity , wherein said tissue flow control member is movable between an undeployed position and a deployed position to engage the tissue during the firing stroke of the fastening instrument , wherein said fastener cartridge further comprises a sled configured to eject said fasteners from said cartridge body during the firing stroke of the fastening instrument , wherein said sled is also configured to deploy said tissue flow control member during the firing stoke of the fastening instrument characterized in that the deployable tissue flow control member is deployed to grip a portion of tissue in advance of the tissue portion being fastened.
Cooling circuit comprising a refrigerant compressor incorporating a suction port and a pressure chamber incorporating a pressure port , a condenser which is arranged in the cooling circuit downstream of the pressure port and comprises a fluid collecting chamber in which a refrigerant reservoir of refrigerant is formed, an evaporator located in the cooling circuit between the condenser and the suction port , a feed unit which is connected at one side to the refrigerant reservoir and to the pressure chamber at the other side and which serves for supplying refrigerant from the refrigerant reservoir to the pressure chamber and which incorporates a pumping unit for the refrigerant, wherein the pumping unit comprises a pressure-tight closed pumping chamber housing which is provided with only one inlet and one outlet as access points, and in that a pumping element which is movable for pumping the refrigerant is arranged in the pumping chamber thereof, characterized in that the pumping element has no mechanical feed-through for a drive of the pumping element , in that the pumping chamber is arranged in a pressure-tight closed pumping chamber housing and in that the pumping element is driven by an electromagnetic force that acts through the pumping chamber housing which, by means of an electromagnet arranged outside the pumping chamber , excites movements in a direction of oscillation of the pumping element configured as a piston , the electromagnet acting by means of its magnetic field on the piston so that this moves in a reciprocating manner in the direction of oscillation or in that the pumping element is driven by a magnetic force acting through the pumping chamber housing , wherein for this purpose the drive of the pumping element results from magnetic coupling between a rotor of a drive motor , in that the rotor is arranged coaxially to the pumping element in an inner chamber of a motor housing , that adjoins the pumping chamber housing , so that the magnetic interaction between the rotor and the pumping element occurs through the motor housing and the pumping chamber housing , and in that in the inner chamber of the motor housing there is arranged a stator surrounding the rotor , the stator causing the rotary movement of the rotor .
A formulation comprising: (2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide), or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, solvate, hydrate, co-crystal, clathrate, or polymorph thereof in an amount of about 0.01 to about 0.15%, and hydroxypropyl β-cyclodextrin or sulfobutyl ether-beta-cyclodextrin in an amount of about 99.1 to about 99.99%, based on the total weight of the formulation, wherein the term "about" contemplates weight percent within 10%, or 5% of the weight percent which is encompassed.
Compounds of formula I R-NR 1 -CO-A-CO-O-X-CO-A-CO-NR 1 -R (I) wherein X is selected from: - a polyoxyethylene chain of formula -(C 2 H 4 O) n -, wherein n is a number corresponding to a molecular weight of said chain ranging from 200 to 4000 Da; - a polyoxypropylene chain of formula -(C 3 H 6 O) m -, wherein m is a number corresponding to a molecular weight of said chain ranging from 200 to 4000 Da; - a mixed polyoxyethylene-polyoxypropylene chain containing n oxyethylene units of formula -(C 2 H 4 O)- and m oxypropylene units of formula -(C 3 H 6 O)-, wherein n and m are two numbers the sum of which determines a molecular weight of said mixed chain ranging from 200 to 4000 Da; R is C 1 -C 4 alkyl, phenyl, C 2 -C 4 aminoalkyl, C 2 -C 4 hydroxyalkyl, benzyl, or a group of formula -CH 2 -CH 2 -NH-(CH 2 -CH 2 -NH) p -CH 2 -CH 2 -NH 2 wherein p is zero or 1; R 1 is hydrogen or C 1 -C 4 alkyl; A is a 1,2-phenylene, ethylene, propylene or vinylene group or a group of formula X is selected from: - a polyoxyethylene chain of formula -(C 2 H 4 O) n -, wherein n is a number corresponding to a molecular weight of said chain ranging from 200 to 4000 Da; - a polyoxypropylene chain of formula -(C 3 H 6 O) m -, wherein m is a number corresponding to a molecular weight of said chain ranging from 200 to 4000 Da; - a mixed polyoxyethylene-polyoxypropylene chain containing n oxyethylene units of formula -(C 2 H 4 O)- and m oxypropylene units of formula -(C 3 H 6 O)-, wherein n and m are two numbers the sum of which determines a molecular weight of said mixed chain ranging from 200 to 4000 Da; - a polyoxyethylene chain of formula -(C 2 H 4 O) n -, wherein n is a number corresponding to a molecular weight of said chain ranging from 200 to 4000 Da; - a polyoxypropylene chain of formula -(C 3 H 6 O) m -, wherein m is a number corresponding to a molecular weight of said chain ranging from 200 to 4000 Da; - a mixed polyoxyethylene-polyoxypropylene chain containing n oxyethylene units of formula -(C 2 H 4 O)- and m oxypropylene units of formula -(C 3 H 6 O)-, wherein n and m are two numbers the sum of which determines a molecular weight of said mixed chain ranging from 200 to 4000 Da; R is C 1 -C 4 alkyl, phenyl, C 2 -C 4 aminoalkyl, C 2 -C 4 hydroxyalkyl, benzyl, or a group of formula -CH 2 -CH 2 -NH-(CH 2 -CH 2 -NH) p -CH 2 -CH 2 -NH 2 wherein p is zero or 1; R 1 is hydrogen or C 1 -C 4 alkyl; A is a 1,2-phenylene, ethylene, propylene or vinylene group or a group of formula
Screw-spindle pump having a spindle housing in which a drive spindle and at least one running spindle , which meshes with said drive spindle, are accommodated in spindle bores and which has an axial fluid inlet and an axial fluid outlet, and having an outer housing which accommodates the spindle housing , characterized in that either provision is made at the spindle housing , which consists of plastic, in the region of the fluid outlet of a supporting device which axially supports the at least one running spindle and which comprises an axially projecting supporting pin , or provision is made at a housing plate consisting of plastic, which is mounted onto the outer housing and which axially closes the outer housing , of a supporting device which axially supports the at least one running spindle and which comprises an axially projecting supporting pin .
A sports shoe comprising: a sole to which are attached cleats used to prevent slippage along a ground surface; an upper part ; a flexible toe cap attached to the sole and the upper part and configured for primary contact with an object while kicking such object; wherein: the flexible toe cap is hollow and made from materials with elastic characteristics; the flexible toe cap is attached to the sole and the upper part in a vertical plane at attachment points that are adapted to reside at a tarsometatarsal joint of a wearer; characterized in that the flexible toe cap is otherwise unattached to the remainder of the sports shoe, wherein the flexible toe cap is unconnected to the sole at any point forward of the attachment points which are arranged forward of the tarsometatarsal joint of the wearer ; and wherein, in use, the flexible toe cap extends longitudinally forward of the toes of a wearer by a distance of at least two centimeters. a sole to which are attached cleats used to prevent slippage along a ground surface; an upper part ; a flexible toe cap attached to the sole and the upper part and configured for primary contact with an object while kicking such object; wherein: the flexible toe cap is hollow and made from materials with elastic characteristics; the flexible toe cap is attached to the sole and the upper part in a vertical plane at attachment points that are adapted to reside at a tarsometatarsal joint of a wearer; characterized in that the flexible toe cap is otherwise unattached to the remainder of the sports shoe, wherein the flexible toe cap is unconnected to the sole at any point forward of the attachment points which are arranged forward of the tarsometatarsal joint of the wearer ; and wherein, in use, the flexible toe cap extends longitudinally forward of the toes of a wearer by a distance of at least two centimeters. the flexible toe cap is hollow and made from materials with elastic characteristics; the flexible toe cap is attached to the sole and the upper part in a vertical plane at attachment points that are adapted to reside at a tarsometatarsal joint of a wearer; characterized in that the flexible toe cap is otherwise unattached to the remainder of the sports shoe, wherein the flexible toe cap is unconnected to the sole at any point forward of the attachment points which are arranged forward of the tarsometatarsal joint of the wearer ; and wherein, in use, the flexible toe cap extends longitudinally forward of the toes of a wearer by a distance of at least two centimeters.
An aerosol actuator , comprising: a body , comprising: a cap opening at one end of the body; an opening in at least a portion of the body adjacent a cap opening; a container opening at an opposite end of the body; and a raised boss ; a cap ; a discharge manifold opening defined by the cap and the opening in the body; a manifold seated within an interior of the body, the manifold comprising: an input end seated in the raised boss; a discharge end 147 positioned in the discharge manifold opening; and at least one manifold bearing rib positioned between the input end and the discharge end; a trigger pivotally seated with the body; and at least one trigger bearing rib extending from the trigger. a body , comprising: a cap opening at one end of the body; an opening in at least a portion of the body adjacent a cap opening; a container opening at an opposite end of the body; and a raised boss ; a cap opening at one end of the body; an opening in at least a portion of the body adjacent a cap opening; a container opening at an opposite end of the body; and a raised boss ; a cap ; a discharge manifold opening defined by the cap and the opening in the body; a manifold seated within an interior of the body, the manifold comprising: an input end seated in the raised boss; a discharge end 147 positioned in the discharge manifold opening; and at least one manifold bearing rib positioned between the input end and the discharge end; an input end seated in the raised boss; a discharge end 147 positioned in the discharge manifold opening; and at least one manifold bearing rib positioned between the input end and the discharge end; a trigger pivotally seated with the body; and at least one trigger bearing rib extending from the trigger.