mhurhangee/patent-ind-claim-en huggingface dataset:
A method for detecting an underfill condition in an electrochemical biosensor, comprising: applying a pulsed test excitation signal to a sample of a biological fluid, the test excitation signal including at least first and second test pulses separated by a test relaxation where the electrical signal is off; switching the test excitation signal to at least one different amplitude; generating during a first time interval a first test output electrical signal from the first test pulse and during a second time interval a second test output electrical signal from the second test pulse; measuring the first test output signal from the first test pulse; measuring the second test output signal from the second test pulse; subtracting a value of the first test output electrical signal from a value of the second test output electrical signal to determine a value change between the first test output electrical signal and the second test output electrical signal; comparing the value change to a value of at least one underfill threshold; and detecting if the electrochemical biosensor is underfilled based on the comparing between the value change and the at least one underfill threshold. applying a pulsed test excitation signal to a sample of a biological fluid, the test excitation signal including at least first and second test pulses separated by a test relaxation where the electrical signal is off; switching the test excitation signal to at least one different amplitude; generating during a first time interval a first test output electrical signal from the first test pulse and during a second time interval a second test output electrical signal from the second test pulse; measuring the first test output signal from the first test pulse; measuring the second test output signal from the second test pulse; subtracting a value of the first test output electrical signal from a value of the second test output electrical signal to determine a value change between the first test output electrical signal and the second test output electrical signal; comparing the value change to a value of at least one underfill threshold; and detecting if the electrochemical biosensor is underfilled based on the comparing between the value change and the at least one underfill threshold.
A cartridge system , comprising a tubular bag containing a viscous material, a cylindrical sleeve having a sleeve wall which completely surrounds the tubular bag , the sleeve having a dispensing-side end and a distal end opposite the dispensing-side end , a closure element which is arranged at the distal end of the sleeve and is releasably connected to the sleeve , and a shoulder element which is arranged at the dispensing-side end of the sleeve and is detachably connected to the sleeve , the shoulder element comprising a central through-flow channel and an outlet opening for dispensing the viscous material from the cartridge system and having at least one piercing point for piercing the tubular bag , the shoulder element having a compression ring which protrudes concentrically to the sleeve wall into an interior of the sleeve delimited by the sleeve wall , and the outer diameter of which compression ring is reduced compared to the inner diameter of the sleeve such that an annular gap is formed between the sleeve wall and the compression ring , a compression chamber being formed inside the compression ring , into which compression chamber the at least one piercing point protrudes, characterized in that the compression ring protrudes further into the interior of the sleeve than the at least one piercing point .
A substrate comprising a base layer having a first principal surface defining a plurality of first trenches and intervening first lands , characterized in that the substrate includes a cover layer of thickness greater than 5μm provided over said first principal surface of the base layer and covering the first trenches and first lands substantially conformally, wherein: the surface of the cover layer remote from the first principal surface of the base layer comprises a plurality of second trenches and intervening second lands defined at a smaller scale than the first trenches and first lands, the width of the first lands is greater than 1μm, and a ratio R = D/H is greater than 0.5 where D is the size of the free space between the surfaces of the cover layer covering two adjacent first lands , whereby the surfaces are provided by sidewalls of the trenches facing each other, and H is the height of the first lands measured from the first principal surface . the surface of the cover layer remote from the first principal surface of the base layer comprises a plurality of second trenches and intervening second lands defined at a smaller scale than the first trenches and first lands, the width of the first lands is greater than 1μm, and a ratio R = D/H is greater than 0.5 where D is the size of the free space between the surfaces of the cover layer covering two adjacent first lands , whereby the surfaces are provided by sidewalls of the trenches facing each other, and H is the height of the first lands measured from the first principal surface .
A process for producing a nanocellulose material, said process comprising: (a) providing a lignocellulosic biomass feedstock; (b) digesting said feedstock with a reaction solution consisting essentially of (i) steam and/or (ii) hot water in a digestor under effective reaction conditions to produce a digested stream containing cellulose-rich solids, hemicellulose oligomers, and lignin, wherein step (b) is conducted at a digestion temperature from 140°C to 210°C; (c) optionally washing said cellulose-rich solids to remove at least a portion of said hemicellulose oligomers and/or at least a portion of said lignin from said cellulose-rich solids; (d) mechanically treating said cellulose-rich solids to form a nanocellulose material containing cellulose nanofibrils and/or cellulose nanocrystals; and (e) recovering said nanocellulose material. (a) providing a lignocellulosic biomass feedstock; (b) digesting said feedstock with a reaction solution consisting essentially of (i) steam and/or (ii) hot water in a digestor under effective reaction conditions to produce a digested stream containing cellulose-rich solids, hemicellulose oligomers, and lignin, wherein step (b) is conducted at a digestion temperature from 140°C to 210°C; (c) optionally washing said cellulose-rich solids to remove at least a portion of said hemicellulose oligomers and/or at least a portion of said lignin from said cellulose-rich solids; (d) mechanically treating said cellulose-rich solids to form a nanocellulose material containing cellulose nanofibrils and/or cellulose nanocrystals; and (e) recovering said nanocellulose material.
A process for tanning animal hides comprising the steps of: - providing a container comprising a pickled hide, a tanning agent and optionally an aqueous solution, where the total amount of water in the container is no more than 110% of the total water that can be retained by the pickled animal hide, and where the total amount of tanning agent in the container is no more than 110% of the total tanning agent that can be retained by the pickled animal hide, and - basifying the animal hide to bind the tanning agent in the animal hide, - where the pressure inside the container is within the range of 50-150% of the pressure outside the container or is at atmospheric pressure. - providing a container comprising a pickled hide, a tanning agent and optionally an aqueous solution, where the total amount of water in the container is no more than 110% of the total water that can be retained by the pickled animal hide, and where the total amount of tanning agent in the container is no more than 110% of the total tanning agent that can be retained by the pickled animal hide, and - basifying the animal hide to bind the tanning agent in the animal hide, - where the pressure inside the container is within the range of 50-150% of the pressure outside the container or is at atmospheric pressure.
A robotic system comprising: a soft robot comprising (i) a plurality of actuators each including at least one of a plurality of fluid channels, and (ii) a pressurizing inlet coupled to the plurality of fluid channels , wherein the pressurizing inlet is configured to receive a pressurized fluid to pressurize the plurality of fluid channels to cause a movement of the soft robot; and wherein the robotic system further comprises: a hard robot coupled to the soft robot , configured to provide locomotion to the robotic system ; the robotic system characterized in that it further comprises a robotic control system coupled to the soft robot and the hard robot , wherein the robotic control system is configured to provide the pressurized fluid to the pressurizing inlet. (i) a plurality of actuators each including at least one of a plurality of fluid channels, and (ii) a pressurizing inlet coupled to the plurality of fluid channels , wherein the pressurizing inlet is configured to receive a pressurized fluid to pressurize the plurality of fluid channels to cause a movement of the soft robot; and wherein the robotic system further comprises: a hard robot coupled to the soft robot , configured to provide locomotion to the robotic system ; the robotic system characterized in that it further comprises a robotic control system coupled to the soft robot and the hard robot , wherein the robotic control system is configured to provide the pressurized fluid to the pressurizing inlet. a hard robot coupled to the soft robot , configured to provide locomotion to the robotic system ; the robotic system characterized in that it further comprises a robotic control system coupled to the soft robot and the hard robot , wherein the robotic control system is configured to provide the pressurized fluid to the pressurizing inlet.
A computer implemented method comprising: processing data from a digital design for an orthodontic aligner to determine a probability that the orthodontic aligner associated with the digital design will be damaged during manufacturing of the orthodontic aligner or subsequent use of the orthodontic aligner ; making a comparison of the probability that the orthodontic aligner associated with the digital design will be damaged to a probability threshold ; determining whether the orthodontic aligner is a high risk orthodontic aligner based on a result of the comparison ; and responsive to determining that the orthodontic aligner is a high risk orthodontic aligner, performing at least one of a) a corrective action or b) selecting a manufacturing flow for high risk orthodontic aligners to reduce the probability that the orthodontic aligner associated with the digital design will be damaged. processing data from a digital design for an orthodontic aligner to determine a probability that the orthodontic aligner associated with the digital design will be damaged during manufacturing of the orthodontic aligner or subsequent use of the orthodontic aligner ; making a comparison of the probability that the orthodontic aligner associated with the digital design will be damaged to a probability threshold ; determining whether the orthodontic aligner is a high risk orthodontic aligner based on a result of the comparison ; and responsive to determining that the orthodontic aligner is a high risk orthodontic aligner, performing at least one of a) a corrective action or b) selecting a manufacturing flow for high risk orthodontic aligners to reduce the probability that the orthodontic aligner associated with the digital design will be damaged.
An electrical impedance tomography based flow monitoring system, comprising: a flow accepting pipe coupled to a cylindrical grid of m x n electrodes , wherein m is an integer greater than 3 representing a number of circumferential grid positions and n is an integer greater than 2 representing a number of axial grid positions, with each combination of adjacent circumferential grid positions and adjacent axial grid positions defining a cell comprising four electrodes electrically connectable in various combinations by a switch, wherein the switches are set to connect the electrodes into multiple axially-extending arrays ; and a controller coupled to the multiple axially-extending arrays to acquire multi-point electrical tomography measurements, wherein the controller processes the measurements to derive a monitored quantity. a flow accepting pipe coupled to a cylindrical grid of m x n electrodes , wherein m is an integer greater than 3 representing a number of circumferential grid positions and n is an integer greater than 2 representing a number of axial grid positions, with each combination of adjacent circumferential grid positions and adjacent axial grid positions defining a cell comprising four electrodes electrically connectable in various combinations by a switch, wherein the switches are set to connect the electrodes into multiple axially-extending arrays ; and a controller coupled to the multiple axially-extending arrays to acquire multi-point electrical tomography measurements, wherein the controller processes the measurements to derive a monitored quantity.
A non-aqueous electrolyte for a lithium-ion battery, comprising a lithium salt, a non-aqueous organic solvent, and one or more of a compound represented by Structural Formula 1, wherein R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are each independently selected from hydrogen, a fluorine atom or a group having 1 to 5 carbon atoms.
A compound of formula (I): or a tautomeric or a stereochemically isomeric form, a pharmaceutically acceptable salt or a solvate thereof; wherein X is CR 4 , N or NR 3 ; wherein • when X is CR 4 , then U represents nitrogen and R 6 represents oxo; or • when X is N, then U represents carbon and R 6 represents hydroxymethyl or - CH(OR x )CH 2 OR z ; or • when X is NR 3 , then U represents carbon and R 6 represents oxo; dashed bond (-------) represents a single or double bond wherein at least two of said dashed bonds represent a double bond; R 1 and R 2 independently represent hydrogen or methyl; R 3 represents hydrogen, methyl or-NH 2 ; R 4 represents hydrogen, methyl, hydroxymethyl, -NH 2 or fluorine; R 5 represents unsubstituted n-butyl or benzyl substituted on the phenyl group by one or two fluorines; and R x and R z independently represent hydrogen or methyl. • when X is CR 4 , then U represents nitrogen and R 6 represents oxo; or • when X is N, then U represents carbon and R 6 represents hydroxymethyl or - CH(OR x )CH 2 OR z ; or • when X is NR 3 , then U represents carbon and R 6 represents oxo; dashed bond (-------) represents a single or double bond wherein at least two of said dashed bonds represent a double bond; R 1 and R 2 independently represent hydrogen or methyl; R 3 represents hydrogen, methyl or-NH 2 ; R 4 represents hydrogen, methyl, hydroxymethyl, -NH 2 or fluorine; R 5 represents unsubstituted n-butyl or benzyl substituted on the phenyl group by one or two fluorines; and R x and R z independently represent hydrogen or methyl. dashed bond (-------) represents a single or double bond wherein at least two of said dashed bonds represent a double bond; R 1 and R 2 independently represent hydrogen or methyl; R 3 represents hydrogen, methyl or-NH 2 ; R 4 represents hydrogen, methyl, hydroxymethyl, -NH 2 or fluorine; R 5 represents unsubstituted n-butyl or benzyl substituted on the phenyl group by one or two fluorines; and R x and R z independently represent hydrogen or methyl.
An aqueous shop primer comprising: (A) 25 to 80 wt% of a polysilane sol obtained by the condensation reaction of at least one silane and comprising a 2D or 3D network of siloxane {Si-O-Si} bonds and a plurality of free silanol functionalities; (B) 0.5 to 15 wt% of an accelerator selected from at least one of zinc phosphate, zinc oxide, calcium strontium zinc phosphosilicate, zirconium hydrogen phosphate, iron phosphide, calcium zirconate, barium zirconate, zirconium nitride, zinc titanate and iron(II) titanate; (C) 15 to 40 wt% of at least one anticorrosive pigment comprising pure zinc or a zinc alloy ; (D) 0.5 to 10 wt% microspheres. (A) 25 to 80 wt% of a polysilane sol obtained by the condensation reaction of at least one silane and comprising a 2D or 3D network of siloxane {Si-O-Si} bonds and a plurality of free silanol functionalities; (B) 0.5 to 15 wt% of an accelerator selected from at least one of zinc phosphate, zinc oxide, calcium strontium zinc phosphosilicate, zirconium hydrogen phosphate, iron phosphide, calcium zirconate, barium zirconate, zirconium nitride, zinc titanate and iron(II) titanate; (C) 15 to 40 wt% of at least one anticorrosive pigment comprising pure zinc or a zinc alloy ; (D) 0.5 to 10 wt% microspheres.
An isolated Protoxin-II variant that inhibits human Nav1.7 activity, comprising: an amino acid sequence YCQKWMQTCDSERKCCEGMVCRLWCKKKLL-COOH (SEQ ID NO: 425), wherein residue Y1, S11, E12, K14, E17, G18, M19, and/or L29 is substituted with a non-natural amino acid, wherein residue number is according to SEQ ID NO: 1, wherein the amino acid sequence has an IC 50 for human Nav1.7 activity of about 30 x 10 -9 M or less, wherein the IC 50 value is measured using a membrane depolarization assay using fluorescence resonance energy transfer (FRET) in the presence of 25x10 -6 M 3-veratroylveracevine in HEK293 cells stably expressing human Nav1.7 and using bis-(1,3-diethylthiobarbituric acid) trimethine oxonol as an electron acceptor and Trisodium 8-octadecyloxypyrene-1,3,6-trisulfonate as a donor by exciting the donor at 390-420 nm and measuring FRET at 515-575 nm. an amino acid sequence YCQKWMQTCDSERKCCEGMVCRLWCKKKLL-COOH (SEQ ID NO: 425), wherein residue Y1, S11, E12, K14, E17, G18, M19, and/or L29 is substituted with a non-natural amino acid, wherein residue number is according to SEQ ID NO: 1, wherein the amino acid sequence has an IC 50 for human Nav1.7 activity of about 30 x 10 -9 M or less, wherein the IC 50 value is measured using a membrane depolarization assay using fluorescence resonance energy transfer (FRET) in the presence of 25x10 -6 M 3-veratroylveracevine in HEK293 cells stably expressing human Nav1.7 and using bis-(1,3-diethylthiobarbituric acid) trimethine oxonol as an electron acceptor and Trisodium 8-octadecyloxypyrene-1,3,6-trisulfonate as a donor by exciting the donor at 390-420 nm and measuring FRET at 515-575 nm.
A method performed by a device manager for controlling program components in a network device , wherein said controlling program components control the operation of said network device , and wherein the network device is used for handling data traffic in a communication network , the method comprising: - identifying a policy out of a set of predefined policies having priorities so that a policy with a first priority overrides a conflicting policy with a second priority lower than the first priority, the identified policy comprising rules which determine how the network device should operate in the communication network, - identifying program components for the network device required to fulfil the identified and prioritized policy, - determining existing program components present in the network device , and - pushing to the network device one or more of the required program components absent in said existing program components in the network device . - identifying a policy out of a set of predefined policies having priorities so that a policy with a first priority overrides a conflicting policy with a second priority lower than the first priority, the identified policy comprising rules which determine how the network device should operate in the communication network, - identifying program components for the network device required to fulfil the identified and prioritized policy, - determining existing program components present in the network device , and - pushing to the network device one or more of the required program components absent in said existing program components in the network device .
A machining apparatus comprising: a mechanism adapted to cause a workpiece (W) to oppose a tool mounted on a spindle, a mechanism adapted to move the workpiece (W) in three axial directions with computer numerical control, a housing unit adapted to house a plurality of types of tools, an automatic tool changing device adapted to pick up a tool from the housing unit and to replace a tool mounted on the spindle with the tool picked up, and a non-contact sensor adapted to measure the surface shape of the workpiece (W), wherein the non-contact sensor is housed in the housing unit , the automatic tool changing device is capable of picking up the non-contact sensor from the housing unit and replacing the tool mounted on the spindle with the non-contact sensor , the non-contact sensor comprises a light irradiation unit adapted to apply a line light to the workpiece (W), and an imaging unit adapted to capture an image of the line light reflected from the workpiece (W), and the light irradiation unit is configured to apply the line light in an oblique direction to the workpiece (W). a mechanism adapted to cause a workpiece (W) to oppose a tool mounted on a spindle, a mechanism adapted to move the workpiece (W) in three axial directions with computer numerical control, a housing unit adapted to house a plurality of types of tools, an automatic tool changing device adapted to pick up a tool from the housing unit and to replace a tool mounted on the spindle with the tool picked up, and a non-contact sensor adapted to measure the surface shape of the workpiece (W), wherein the non-contact sensor is housed in the housing unit , the automatic tool changing device is capable of picking up the non-contact sensor from the housing unit and replacing the tool mounted on the spindle with the non-contact sensor , the non-contact sensor comprises a light irradiation unit adapted to apply a line light to the workpiece (W), and an imaging unit adapted to capture an image of the line light reflected from the workpiece (W), and the light irradiation unit is configured to apply the line light in an oblique direction to the workpiece (W).