Method for calibrating an MR control sequence comprising a first radio-frequency pulse and a second radio-frequency pulse for a magnetic resonance examination of an examination region comprising a first substance and a second substance of an examination object by means of the MR control sequence in accordance with the following method steps: - determination of a first reference value in the form of a first reference frequency and/or a first reference voltage for the first radio-frequency pulse for resonant excitation of the first substance , wherein the first reference frequency specifies a basic frequency of the first radio-frequency pulse and the first reference voltage specifies a measure for scaling an amplitude of the first radio-frequency pulse, - determination of a second reference value in the form of a second reference frequency and/or a second reference voltage for the second radio-frequency pulse for resonant excitation of the second substance , wherein the second reference frequency specifies a basic frequency of the second radio-frequency pulse and the second reference voltage specifies a measure for scaling an amplitude of the second radio-frequency pulse, wherein the determination of the second reference value comprises a selective excitation comprising a resonant excitation of the second substance and a determination of a spatial distribution of the second substance based on the selective excitation of the second substance and takes place taking into account the spatial distribution of the second substance and a spatial distribution of a BO field and/or a B1 field, - calibration of the MR control sequence by assignment of the first reference value to the first radio-frequency pulse and assignment of the second reference value to the second radio-frequency pulse . - determination of a first reference value in the form of a first reference frequency and/or a first reference voltage for the first radio-frequency pulse for resonant excitation of the first substance , wherein the first reference frequency specifies a basic frequency of the first radio-frequency pulse and the first reference voltage specifies a measure for scaling an amplitude of the first radio-frequency pulse, - determination of a second reference value in the form of a second reference frequency and/or a second reference voltage for the second radio-frequency pulse for resonant excitation of the second substance , wherein the second reference frequency specifies a basic frequency of the second radio-frequency pulse and the second reference voltage specifies a measure for scaling an amplitude of the second radio-frequency pulse, wherein the determination of the second reference value comprises a selective excitation comprising a resonant excitation of the second substance and a determination of a spatial distribution of the second substance based on the selective excitation of the second substance and takes place taking into account the spatial distribution of the second substance and a spatial distribution of a BO field and/or a B1 field, - calibration of the MR control sequence by assignment of the first reference value to the first radio-frequency pulse and assignment of the second reference value to the second radio-frequency pulse . <EOS>