mhurhangee/patent-ind-claim-en huggingface dataset:
An optical element comprising an optical surface having a fine uneven structure, wherein the fine uneven structure is a microstructure with a period (P) smaller than a wavelength of light and includes a plurality of holes , and the plurality of holes has a hole depth H and a surface opening diameter φt which satisfy an expression of 0.3 ≤ H/φt ≤ 0.6; characterized in that the plurality of holes has a cylindrical shape proximal to a bottom surface and a circular truncated cone shape distal to the bottom surface and proximal to a top surface of the optical surface , the circular truncated cone shape having a diameter gradually increasing toward the top surface of the optical surface , and an angle θ between the top surface of the optical surface and a side surface of the circular truncated cone shape of the plurality of holes satisfies 78° ≤ θ ≤ 85°. the fine uneven structure is a microstructure with a period (P) smaller than a wavelength of light and includes a plurality of holes , and the plurality of holes has a hole depth H and a surface opening diameter φt which satisfy an expression of 0.3 ≤ H/φt ≤ 0.6; characterized in that the plurality of holes has a cylindrical shape proximal to a bottom surface and a circular truncated cone shape distal to the bottom surface and proximal to a top surface of the optical surface , the circular truncated cone shape having a diameter gradually increasing toward the top surface of the optical surface , and an angle θ between the top surface of the optical surface and a side surface of the circular truncated cone shape of the plurality of holes satisfies 78° ≤ θ ≤ 85°.
A bodily-fluid transfer device for obtaining bodily fluid from a patient, comprising: a housing ; a channel at least partially disposed in the housing, the channel defining at least a portion of a first fluid flow path for receiving a first volume of bodily fluid from the patient; and a valve disposed along the first fluid flow path, the valve configured to transition from a closed configuration to an open configuration in response to a difference in pressure between a proximal end and a distal end of the valve, the valve further configured to return to the closed configuration after the first volume of bodily fluid is received in the bodily-fluid transfer device, the bodily-fluid transfer device with the valve in the closed configuration configured to: sequester at least a portion of the first volume of bodily fluid and contaminants contained therein and to allow a second volume of bodily fluid to flow from the patient into a second fluid flow path at least partially disposed in the housing, at least a portion of the second fluid flow path being formed separately from the first fluid flow path; and provide a sample of bodily fluid into a sample container, the sample of bodily fluid having reduced contamination due to the sequestration of the portion of the first volume of bodily fluid and contaminants contained therein. a housing ; a channel at least partially disposed in the housing, the channel defining at least a portion of a first fluid flow path for receiving a first volume of bodily fluid from the patient; and a valve disposed along the first fluid flow path, the valve configured to transition from a closed configuration to an open configuration in response to a difference in pressure between a proximal end and a distal end of the valve, the valve further configured to return to the closed configuration after the first volume of bodily fluid is received in the bodily-fluid transfer device, the bodily-fluid transfer device with the valve in the closed configuration configured to: sequester at least a portion of the first volume of bodily fluid and contaminants contained therein and to allow a second volume of bodily fluid to flow from the patient into a second fluid flow path at least partially disposed in the housing, at least a portion of the second fluid flow path being formed separately from the first fluid flow path; and provide a sample of bodily fluid into a sample container, the sample of bodily fluid having reduced contamination due to the sequestration of the portion of the first volume of bodily fluid and contaminants contained therein. sequester at least a portion of the first volume of bodily fluid and contaminants contained therein and to allow a second volume of bodily fluid to flow from the patient into a second fluid flow path at least partially disposed in the housing, at least a portion of the second fluid flow path being formed separately from the first fluid flow path; and provide a sample of bodily fluid into a sample container, the sample of bodily fluid having reduced contamination due to the sequestration of the portion of the first volume of bodily fluid and contaminants contained therein.
An anti-IL23 antibody for use in a method of treating fumaric acid ester-resistant plaque psoriasis in a patient, said method comprising administering a therapeutically-effective amount of the anti-IL23 antibody to said patient, wherein said anti-IL23 antibody comprises a set of six CDRs, HCDR1, HCDR2, HCDR3, LCDR1, LCDR2 and LCDR3, wherein HCDR1 has the amino acid sequence of SEQ ID NO: 5; HCDR2 has the amino acid sequence of SEQ ID NO: 6; HCDR3 has the amino acid sequence of SEQ ID NO: 7; LCDR1 has the amino acid sequence of SEQ ID NO: 8; LCDR2 has the amino acid of SEQ ID NO: 9; and LCDR3 has the amino acid sequence of SEQ ID NO: 10.
A magnesium ion selective membrane comprising: a polymer material; a magnesium-selective material which comprises an ionophore, wherein the ionophore comprises a triamide compound; and a plasticizer comprising a measured logP value of greater than 5.8 and less than 12.8, wherein the plasticizer comprises a nitrophenyl group and a hydrophobic chain extending therefrom with a structure of wherein R 1 is a straight-chain alkyl group having 10, 11, 12 or 14 carbons. a polymer material; a magnesium-selective material which comprises an ionophore, wherein the ionophore comprises a triamide compound; and a plasticizer comprising a measured logP value of greater than 5.8 and less than 12.8, wherein the plasticizer comprises a nitrophenyl group and a hydrophobic chain extending therefrom with a structure of wherein R 1 is a straight-chain alkyl group having 10, 11, 12 or 14 carbons.
Timepiece comprising a case having a middle , a back cover and a bezel , a movement and a vibration-generating device intended to produce at least one sound, the latter two accommodated in said case , a vibration-amplifying device for amplifying the vibrations generated by said vibration-generating device and a membrane arranged to receive said amplified vibrations and generate a sound from the inside to the outside of the timepiece, said vibration-amplifying device comprising a lever pivotally mounted on a support in a pivoting plane non-parallel to the plane of the membrane and arranged to be actuated by a transmission member cooperating with the vibration-generating device to transmit the vibrations to the lever , said lever likewise being integral with the membrane at least translationally in the pivoting plane such that a movement of the transmission member , generated by the vibration of said transmission member linked to the vibration-generating device and transmitted to the membrane by way of the lever actuated by said transmission member , generates an amplified movement of said membrane , so as to generate an amplified sound, the timepiece comprising a compression chamber which is arranged to amplify the sound which has been generated by the movement of the membrane before it emerges to the outside, the compression chamber being closed by a wall disposed downstream of the membrane and having at least one opening , the dimensions of which are selected in relation to the surface area of the membrane as a function of the desired sound amplification.
A method for selecting a variant of a reference antibody variable domain, wherein the reference antibody variable domain has at least one of i) an unpaired Cys-residue in the variable domain or the HVR, ii) a glycosylation site, or iii) a post-translationally modified Asp, Asn or Met amino acid residue, the method comprising the following steps: - aligning antibody variable domain encoding nucleic acids produced by sequencing nucleic acids from a multitude of B-cell clones each producing an antibody specifically binding to the same target as the reference antibody with the sequence of the reference antibody being the template sequence; and - selecting a sequence that has the highest similarity to the reference sequence wherein at least one of the at least one amino acid residue of i) an unpaired Cys-residue in the variable domain or the HVR, ii) a glycosylation site, or iii) a post-translationally modified Asp, Asn or Met amino acid residue of the reference antibody variable domain is replaced by/changed to an amino acid residue that is not post-translationally modified, wherein the B-cells are obtained from the same immunization campaign as the reference antibody, wherein the B-cells have been enriched for antigen-specific antibody expressing B-cells. - aligning antibody variable domain encoding nucleic acids produced by sequencing nucleic acids from a multitude of B-cell clones each producing an antibody specifically binding to the same target as the reference antibody with the sequence of the reference antibody being the template sequence; and - selecting a sequence that has the highest similarity to the reference sequence wherein at least one of the at least one amino acid residue of i) an unpaired Cys-residue in the variable domain or the HVR, ii) a glycosylation site, or iii) a post-translationally modified Asp, Asn or Met amino acid residue of the reference antibody variable domain is replaced by/changed to an amino acid residue that is not post-translationally modified,
A variable magnetization machine controller for a variable magnetization machine , - the variable magnetization machine comprising a rotor comprising a plurality of low-coercive-force magnets and - the variable magnetization machine controller comprising: - a current command module configured to compute a vector current command in a dq axis based on a torque command; - a magnetization module configured to apply a magnetization control pulse to a d-axis current of the vector current command; and characterized in that the variable magnetization machine controller comprising: - a reducing current module configured to apply a reducing current to a q-axis current of the vector current command based on the torque command and one of an estimated torque of the variable magnetization machine and a measured torque of the variable magnetization machine . - the variable magnetization machine comprising a rotor comprising a plurality of low-coercive-force magnets and - the variable magnetization machine controller comprising: - a current command module configured to compute a vector current command in a dq axis based on a torque command; - a magnetization module configured to apply a magnetization control pulse to a d-axis current of the vector current command; and - a current command module configured to compute a vector current command in a dq axis based on a torque command; - a magnetization module configured to apply a magnetization control pulse to a d-axis current of the vector current command; and - a reducing current module configured to apply a reducing current to a q-axis current of the vector current command based on the torque command and one of an estimated torque of the variable magnetization machine and a measured torque of the variable magnetization machine .
A decoding method comprising: - decoding (S220) a block of transform coefficients from a bitstream; - de-quantizing (S230, S240) the decoded block of transform coefficients responsive to a quantization step size and a scaling factor to obtain a dequantized block; and - transforming (S250) said dequantized block into an image block of bitdepth B, characterized in that , in the case where s 1 = 3 × 2 n 1 and s 2 = 2 n 2 , said scaling factor S IQ is substantially equal to 4 3 × 1 s 1 ∗ s 2 × 2 − B − 9 where s1 is the width and s2 the height of the block or vice versa and where s 1 * is the smallest integer equal to a power of 2 that is greater than s1; and wherein, in the case where s 1 = 3 × 2 n 1 and s 2 = 3 × 2 n2 , said scaling factor S IQ is substantially equal to 4 3 × 1 s 1 ∗ s 2 ∗ × 2 − B − 9 where s1 is the width and s2 the height of the block or vice versa and where s 1 * is the smallest integer equal to a power of 2 that is greater than s1 and where s 2 * is the smallest integer equal to a power of 2 that is greater than s2. - decoding (S220) a block of transform coefficients from a bitstream; - de-quantizing (S230, S240) the decoded block of transform coefficients responsive to a quantization step size and a scaling factor to obtain a dequantized block; and - transforming (S250) said dequantized block into an image block of bitdepth B,
Medical sensor assembly comprising a flexible plaster adapted for adhesion on the skin of a patient and a sensor configured for transdermal measuring a physiological parameter, wherein the sensor has a measuring part insertable into the skin and a contact part for providing a signal connection to a measuring unit, wherein the measuring part of the sensor is formed by a flexible flat substrate with electrode pads or conducting paths thereon and the plaster is adhered to an intermediate section of the sensor between the measuring part and the contact part , characterized in that a flap is formed as a partially cut-out or punched segment of the plaster , such that an opening is provided in the plaster for the passage of the intermediate section of the sensor , and the flap is connected to a flat side of the substrate.
A method of producing a printed security-enhanced document, the method comprising: (a) generating secure and non-secure portions of image data, the portions being encoded in PostScript vector graphics; (b) encrypting the secure portions using a one time pad with a generated encryption key , resulting in secure portion of ciphertexts; (c) saving the encryption key in at least one file separate from a PostScript file containing the image data; (d) linking both the encryption key file and the PostScript file in a Raster Image Processor (RIP) interpreting the image data to print PostScript graphics and merging at least one of the secure portion ciphertexts with at least one of the non-secure portions into a secure press run data file; (e) receiving the secure press run data file at the RIP along with an associated decryption key and decrypting the secure portion ciphertext utilizing the corresponding decryption key resulting in a secure cleartext; and (f) feeding the resulting secure cleartext into an imager to produce the printed security-enhanced document including imaging from both the secure and non-secure portions. (a) generating secure and non-secure portions of image data, the portions being encoded in PostScript vector graphics; (b) encrypting the secure portions using a one time pad with a generated encryption key , resulting in secure portion of ciphertexts; (c) saving the encryption key in at least one file separate from a PostScript file containing the image data; (d) linking both the encryption key file and the PostScript file in a Raster Image Processor (RIP) interpreting the image data to print PostScript graphics and merging at least one of the secure portion ciphertexts with at least one of the non-secure portions into a secure press run data file; (e) receiving the secure press run data file at the RIP along with an associated decryption key and decrypting the secure portion ciphertext utilizing the corresponding decryption key resulting in a secure cleartext; and (f) feeding the resulting secure cleartext into an imager to produce the printed security-enhanced document including imaging from both the secure and non-secure portions.
Display module comprising a fixed frame and at least two substantially rigid display members , wherein : - said display members each comprise a display portion of a pattern (M), said display portions being complementary to each other such that they form said pattern (M) in at least one relative position of said display members , - at least one of the display portions being integral with and movable relative to the frame by means of a deformable link at least between a first rest position in which said display portions are spaced apart from each other and a display position in which said display portions are counter-applied to each other to form and display said pattern (M), - said display member or members movable relative to the frame cooperate with an actuating push-button arranged to transmit a displacement force of this display member by elastic deformation around its deformable link or links from said rest position to said display position, characterized in that - said display members , the frame and the deformable link or links form a monolithic piece. - said display members each comprise a display portion of a pattern (M), said display portions being complementary to each other such that they form said pattern (M) in at least one relative position of said display members , - at least one of the display portions being integral with and movable relative to the frame by means of a deformable link at least between a first rest position in which said display portions are spaced apart from each other and a display position in which said display portions are counter-applied to each other to form and display said pattern (M), - said display member or members movable relative to the frame cooperate with an actuating push-button arranged to transmit a displacement force of this display member by elastic deformation around its deformable link or links from said rest position to said display position, characterized in that - said display members , the frame and the deformable link or links form a monolithic piece.
An apparatus for software attestation, comprising a processing circuitry configured to: initialize an enclave in a trusted execution environment, TEE, wherein the enclave includes an operation system, OS, library ; perform software attestation to verify an identity of the enclave ; and execute an application inside the enclave using the OS library ; characterized in that performing the software attestation includes attestation of a content of a disk image associated with the application . initialize an enclave in a trusted execution environment, TEE, wherein the enclave includes an operation system, OS, library ; perform software attestation to verify an identity of the enclave ; and execute an application inside the enclave using the OS library ; characterized in that performing the software attestation includes attestation of a content of a disk image associated with the application .
Radiation-emitting device, comprising - a substrate - an organic radiation-emitting functional layer , which emits a primary radiation, and - a radiation decoupling layer which is disposed in the beam path of the primary radiation, wherein - the radiation decoupling layer comprises a partial layer having light-scattering regions, - the radiation decoupling layer comprises, on the side remote from the radiation-emitting functional layer, a microstructure having regularly disposed geometric structural elements , so that the partial layer having the light-scattering regions is situated between the microstructure and the substrate, - the radiation decoupling layer includes the partial layer having the light-scattering regions, which effect a scattering of the primary radiation, - each planar curve, which extends from a maximum of the geometric structural element to the base thereof, comprises in its lowermost third facing the radiation-emitting layer only curvatures which are smaller than any curvature in the corresponding uppermost third of the planar curve, - curvatures in the central third are between the curvatures between the uppermost third and the lowermost third, - planar curves refer to such curves which extend on the outer surface of the corresponding geometric structural element such as degrees of longitude of a globe which extend from the pole to the equator, and - the maxima of mutually adjacent geometric structural elements comprise a spacing of 30 to 500 μm. - a substrate - an organic radiation-emitting functional layer , which emits a primary radiation, and - a radiation decoupling layer which is disposed in the beam path of the primary radiation, - the radiation decoupling layer comprises a partial layer having light-scattering regions, - the radiation decoupling layer comprises, on the side remote from the radiation-emitting functional layer, a microstructure having regularly disposed geometric structural elements , so that the partial layer having the light-scattering regions is situated between the microstructure and the substrate, - the radiation decoupling layer includes the partial layer having the light-scattering regions, which effect a scattering of the primary radiation, - each planar curve, which extends from a maximum of the geometric structural element to the base thereof, comprises in its lowermost third facing the radiation-emitting layer only curvatures which are smaller than any curvature in the corresponding uppermost third of the planar curve, - curvatures in the central third are between the curvatures between the uppermost third and the lowermost third, - planar curves refer to such curves which extend on the outer surface of the corresponding geometric structural element such as degrees of longitude of a globe which extend from the pole to the equator, and - the maxima of mutually adjacent geometric structural elements comprise a spacing of 30 to 500 μm.
A barrier layer assembly, the assembly comprising a support layer and a film layer bonded thereto, wherein the assembly has a bi-directionally corrugated surface, the support layer is an elastomeric composition, the film layer contains a thermoplastic resin, and the thermoplastic resin is present in the film layer in an amount of 20 wt% to 100 wt%.