mhurhangee/patent-ind-claim-en huggingface dataset:
A method for roughening a metal molded body surface comprising: a laser light irradiation step of irradiating a surface of the metal molded body with laser light at an irradiation rate of 2000 mm/sec or more with an energy density of 1 MW/cm 2 or more using a laser apparatus, characterized in that the laser light irradiation step is a step of irradiating laser light so that laser light-irradiated portions and non-laser light-irradiated portions are generated alternately when the laser light is irradiated to be in a straight line, a curved line, or a combination of a straight line and a curved line on the surface of the metal molded body to be roughened; and, in that the metal molded body is a molded body having a thickness of 10 mm or less at a portion to be irradiated with laser light. a laser light irradiation step of irradiating a surface of the metal molded body with laser light at an irradiation rate of 2000 mm/sec or more with an energy density of 1 MW/cm 2 or more using a laser apparatus, characterized in that the laser light irradiation step is a step of irradiating laser light so that laser light-irradiated portions and non-laser light-irradiated portions are generated alternately when the laser light is irradiated to be in a straight line, a curved line, or a combination of a straight line and a curved line on the surface of the metal molded body to be roughened; and, in that the metal molded body is a molded body having a thickness of 10 mm or less at a portion to be irradiated with laser light.
A method of detecting decreased expression of miR-18b and increased methylation of the 2.5 kilo base (kB) region upstream of miR-18b in a tissue biological sample from a subject, comprising: (i) measuring the expression level of miR-18b in the tissue biological sample and determining the methylation status of the 2.5 kB region upstream of the miR-18b gene in the sample using methylation specific primers following bisulphite treatment, wherein the methylation-specific primers consist of the sequence of SEQ ID NO: 4 and 5; (ii) comparing the expression level of miR-18b in the subject's sample with the mean expression level of miR-18b from one or more control biological samples; (iii) identifying whether the expression level for miR-18b in the sample is decreased in comparison to the mean expression level for miR-18b in one or more control samples, and determining whether the sample has increased methylation for the 2.5 kB region in comparison to the methylation status for the 2.5 kB region in the one or more control samples. (i) measuring the expression level of miR-18b in the tissue biological sample and determining the methylation status of the 2.5 kB region upstream of the miR-18b gene in the sample using methylation specific primers following bisulphite treatment, wherein the methylation-specific primers consist of the sequence of SEQ ID NO: 4 and 5; (ii) comparing the expression level of miR-18b in the subject's sample with the mean expression level of miR-18b from one or more control biological samples; (iii) identifying whether the expression level for miR-18b in the sample is decreased in comparison to the mean expression level for miR-18b in one or more control samples, and determining whether the sample has increased methylation for the 2.5 kB region in comparison to the methylation status for the 2.5 kB region in the one or more control samples.
A single-lobe filter bag for infusion products, the filter bag comprising a length of filter material forming a chamber containing a charge of the infusion product; the length comprising at least: a first closed top end formed by a first join (S1) between two first end edges of the length ; a second closed bottom end ; two sides connecting the first end and the second end of the length , the two sides connecting the first and second ends being at least partly folded onto each other to form a fold towards the inside of the chamber ; characterised in that the second bottom end of the filter bag is closed by a second join (S2) designed to form a stiff flat bottom surface of the filter bag such as to define a stable base for supporting the filter bag , characterised in that the filter bag has a substantially triangular vertical cross section, the second end having two second edges defining a central extension of the second bottom end , said second edges being positioned face to face with each other and being joined in such a way as to form a tab that protrudes from the bottom supporting base and that is elastically compliant in such a way as to be folded and joined stably, by a seal (S4), to the bottom supporting base , thus forming a larger, stiff longitudinal area onto the bottom supporting base to increase its stiffness. a first closed top end formed by a first join (S1) between two first end edges of the length ; a second closed bottom end ; two sides connecting the first end and the second end of the length , the two sides connecting the first and second ends being at least partly folded onto each other to form a fold towards the inside of the chamber ; characterised in that the second bottom end of the filter bag is closed by a second join (S2) designed to form a stiff flat bottom surface of the filter bag such as to define a stable base for supporting the filter bag , characterised in that the filter bag has a substantially triangular vertical cross section, the second end having two second edges defining a central extension of the second bottom end , said second edges being positioned face to face with each other and being joined in such a way as to form a tab that protrudes from the bottom supporting base and that is elastically compliant in such a way as to be folded and joined stably, by a seal (S4), to the bottom supporting base , thus forming a larger, stiff longitudinal area onto the bottom supporting base to increase its stiffness.
A heavy goods vehicle having: a rear axle ; a vehicle frame which is designed as a ladder-type frame and has two main longitudinal members which are spaced apart in parallel; and an electrical drive unit which is arranged between the two main longitudinal members and is arranged behind the rear axle with respect to a forward direction of travel of the heavy goods vehicle , characterized in that an output shaft of the electrical drive unit is oriented in a longitudinal direction of the heavy goods vehicle . a rear axle ; a vehicle frame which is designed as a ladder-type frame and has two main longitudinal members which are spaced apart in parallel; and an electrical drive unit which is arranged between the two main longitudinal members and is arranged behind the rear axle with respect to a forward direction of travel of the heavy goods vehicle , characterized in that an output shaft of the electrical drive unit is oriented in a longitudinal direction of the heavy goods vehicle .
A device for effecting compression of a ciliary muscle of an eye in at least four quadrants, wherein the device comprises a self-expanding wire device , wherein the unexpanded device fits into a hypodermic needle or cannula, wherein the wire device is configured to self-expand within the posterior chamber of the eye between an iris and an anterior capsule , wherein the wire device is expandable circumferentially, characterized in that the wire device comprises four oblique meridians , 45 degree portions of the wire device , and cardinal meridians , vertical and horizontal portions of the wire device , wherein the circumferential expansion is greater in the oblique meridians than in the cardinal meridians , such that the maximally expanded oblique meridians apply pressure to the ciliary muscle while the maximally expanded cardinal meridians do not apply pressure to the horizontal and vertical anterior ciliary blood vessels.
A machine tool including: movement means having a first feed axis (A) and a second feed axis (B) that mutually intersect; a tool post movable with the movement means , a plurality of tools supported on a tool post , a spindle holding a work (W) to be machined by the plurality of tools ; wherein the movement means is composed of two feed mechanisms of one feed mechanism having the first feed axis (A) and another feed mechanism having the second feed axis (B); the plurality of tools is movable as a unit along with movement of the tool post with the movement means , the tool post is movable in a cut-in direction (X1) so that machining with a particular one of the tools is executed, each of the plurality of tools is arranged in parallel along a direction (Y1) orthogonal to the cut-in direction (X1), the tool post is movable on a straight line along a selection axis of the plurality of tools intersecting with the cut-in direction (X1) so that the plurality of tools supported by the tool post is selectively switched, and the cut-in direction (X1) intersects with the first feed axis (A) and the second feed axis (B), characterized in that the plurality of tools is arranged such that blade edges thereof are aligned with the straight line (L) along the selection axis of the tools , one of the first feed axis (A) and the second feed axis (B) is arranged along the straight line (L) along the selection axis of the tools , and respective blade edges of the plurality of tools are staggered in a stepwise fashion in the cut-in direction (X1). movement means having a first feed axis (A) and a second feed axis (B) that mutually intersect; a tool post movable with the movement means , a plurality of tools supported on a tool post , a spindle holding a work (W) to be machined by the plurality of tools ; wherein the movement means is composed of two feed mechanisms of one feed mechanism having the first feed axis (A) and another feed mechanism having the second feed axis (B); the plurality of tools is movable as a unit along with movement of the tool post with the movement means , the tool post is movable in a cut-in direction (X1) so that machining with a particular one of the tools is executed, each of the plurality of tools is arranged in parallel along a direction (Y1) orthogonal to the cut-in direction (X1), the tool post is movable on a straight line along a selection axis of the plurality of tools intersecting with the cut-in direction (X1) so that the plurality of tools supported by the tool post is selectively switched, and the cut-in direction (X1) intersects with the first feed axis (A) and the second feed axis (B), characterized in that the plurality of tools is arranged such that blade edges thereof are aligned with the straight line (L) along the selection axis of the tools , one of the first feed axis (A) and the second feed axis (B) is arranged along the straight line (L) along the selection axis of the tools , and respective blade edges of the plurality of tools are staggered in a stepwise fashion in the cut-in direction (X1).
A filling loop device for a pressurized heating system comprising: means comprising a dead man valve defining a fluid passage having, an inlet port connectable to a fluid supply and an outlet port connectable to a heating system fluid circuit; said dead man valve biased to a normally closed condition to shut off fluid flow through the fluid passage in either direction when unattended, and manually operable to an open condition to permit fluid to flow from the inlet port to the outlet port; said dead man valve having: a casing providing the fluid passage with the inlet port, the outlet port and, a spool chamber ; a spool slidably housed in the spool chamber , said spool including a through passage capable of communicating the inlet port and outlet port for fluid flow therebetween when manually operated, and bias means to urge the spool to the closed condition so that a lower part of the spool obstructs the fluid passage to shut off fluid flow through the inlet port , and characterised in that a drain passage is formed in the lower part of the spool isolated from the fluid passage to communicate between the outlet port and a drain port formed in the lower part of the spool chamber when the bias means displaces the spool to the closed condition. means comprising a dead man valve defining a fluid passage having, an inlet port connectable to a fluid supply and an outlet port connectable to a heating system fluid circuit; said dead man valve biased to a normally closed condition to shut off fluid flow through the fluid passage in either direction when unattended, and manually operable to an open condition to permit fluid to flow from the inlet port to the outlet port; said dead man valve having: a casing providing the fluid passage with the inlet port, the outlet port and, a spool chamber ; a spool slidably housed in the spool chamber , said spool including a through passage capable of communicating the inlet port and outlet port for fluid flow therebetween when manually operated, and bias means to urge the spool to the closed condition so that a lower part of the spool obstructs the fluid passage to shut off fluid flow through the inlet port , and a casing providing the fluid passage with the inlet port, the outlet port and, a spool chamber ; a spool slidably housed in the spool chamber , said spool including a through passage capable of communicating the inlet port and outlet port for fluid flow therebetween when manually operated, and bias means to urge the spool to the closed condition so that a lower part of the spool obstructs the fluid passage to shut off fluid flow through the inlet port , and characterised in that a drain passage is formed in the lower part of the spool isolated from the fluid passage to communicate between the outlet port and a drain port formed in the lower part of the spool chamber when the bias means displaces the spool to the closed condition.
A method of scanning a film of the type including a film substrate carrying a sequence of image frames and a multiplicity of transport perforations spaced apart along the film at a location adjacent the sequence of image frames in a predetermined positional relationship with said image frames, wherein said method includes: illuminating a portion of the film including at least a portion of one or more image frames to be scanned; capturing light transmitted through the film so as to acquire a digitised image including, a captured frame comprising a digitised image of at least a portion of at least one of said image frames, and a plurality of said transport perforations; processing the digitised image including the plurality of transport perforations to detect the location of a plurality of transport perforation edges therein; determining an image offset for the captured frame on the basis of a comparison between a plurality of said detected edges and a plurality of datum locations, each datum location representing a location of an edge of a transport perforation according to the transport perforation's predetermined positional relationship with the captured frame generating a signal representing the image offset to enable alignment of at least the captured frame. illuminating a portion of the film including at least a portion of one or more image frames to be scanned; capturing light transmitted through the film so as to acquire a digitised image including, a captured frame comprising a digitised image of at least a portion of at least one of said image frames, and a plurality of said transport perforations; processing the digitised image including the plurality of transport perforations to detect the location of a plurality of transport perforation edges therein; determining an image offset for the captured frame on the basis of a comparison between a plurality of said detected edges and a plurality of datum locations, each datum location representing a location of an edge of a transport perforation according to the transport perforation's predetermined positional relationship with the captured frame generating a signal representing the image offset to enable alignment of at least the captured frame.
A waste receptacle for animal excreta, the waste receptacle comprising: a housing having a base and at least one sidewall upstanding from the base so as to define an internal housing void ; and a liner insertable into said internal housing void , the housing liner having a liner base and at least one liner sidewall supportable in use so as to be generally upstanding from said liner base , the liner base and said at least one liner sidewall cooperating to define an internal liner void for the receipt of animal litter; wherein the housing and the liner (9; 114) each comprise access ports (5; 124) that cooperate with one another when the liner (9; 114) is received within said internal housing void to allow an animal to enter the housing and access litter provided within said liner void, characterised in that the at least one liner sidewall further comprises a pocket for the storage of a litter scoop , said pocket being provided on an external face of the at least one liner sidewall that is adjacent an internal face of said at least one housing sidewall when the liner (9; 114) is inserted into said internal housing void . a housing having a base and at least one sidewall upstanding from the base so as to define an internal housing void ; and a liner insertable into said internal housing void , the housing liner having a liner base and at least one liner sidewall supportable in use so as to be generally upstanding from said liner base , the liner base and said at least one liner sidewall cooperating to define an internal liner void for the receipt of animal litter; wherein the housing and the liner (9; 114) each comprise access ports (5; 124) that cooperate with one another when the liner (9; 114) is received within said internal housing void to allow an animal to enter the housing and access litter provided within said liner void, characterised in that the at least one liner sidewall further comprises a pocket for the storage of a litter scoop , said pocket being provided on an external face of the at least one liner sidewall that is adjacent an internal face of said at least one housing sidewall when the liner (9; 114) is inserted into said internal housing void .
Method of treatment of an organic waste material in a liquid form comprising: - subjecting the liquid waste material to a first solid/liquid separation step resulting in a clarified fraction and a concentrated fraction ; - subjecting said concentrated fraction to anaerobic fermentation in a biogas reactor resulting in a first digestate ; - subjecting said first digestate and said clarified fraction to an anaerobic fermentation in a UASB reactor resulting in a second digestate ; and - subjecting said second digestate to ultrafiltration and reverse osmosis. - subjecting the liquid waste material to a first solid/liquid separation step resulting in a clarified fraction and a concentrated fraction ; - subjecting said concentrated fraction to anaerobic fermentation in a biogas reactor resulting in a first digestate ; - subjecting said first digestate and said clarified fraction to an anaerobic fermentation in a UASB reactor resulting in a second digestate ; and - subjecting said second digestate to ultrafiltration and reverse osmosis.
A load-carrying vehicle part of a wheeled vehicle comprising, - a first wheel pair and a second wheel pair , wherein the wheels are tyred wheels and in each pair located in sequence and suspended in a respective bogie element on each side of a longitudinal frame member , which extends along a centre line (CL) between said first and second wheel pairs, - a suspension , which is arranged between each bogie element and the frame member on each side of the vehicle part to enable manipulation of the frame member state relative to the respective wheel pairs or to carry the frame member between them in a springing manner, characterized in that each suspension comprises - a first rocker arm and a second rocker arm , wherein the first rocker arm is located in front of the second rocker arm viewed in the vehicle part's normal forward direction of driving, - each rocker arm with its one end is pivotably fastened to a joint in the frame member and with its other end pivotably fastened in a joint in the bogie element . - a first spring leg and a second spring leg , wherein each spring leg with its one end is articulately fastened to the frame member and with its other end is articulately fastened to a rocker arm . - a motion conversion arrangement capable of converting a rotary motion in a joint for one of the rocker arms to a forward and backward translation motion to accommodate changes in distance between the rocker arms' joints. - a first wheel pair and a second wheel pair , wherein the wheels are tyred wheels and in each pair located in sequence and suspended in a respective bogie element on each side of a longitudinal frame member , which extends along a centre line (CL) between said first and second wheel pairs, - a suspension , which is arranged between each bogie element and the frame member on each side of the vehicle part to enable manipulation of the frame member state relative to the respective wheel pairs or to carry the frame member between them in a springing manner, characterized in that each suspension comprises - a first rocker arm and a second rocker arm , wherein the first rocker arm is located in front of the second rocker arm viewed in the vehicle part's normal forward direction of driving, - each rocker arm with its one end is pivotably fastened to a joint in the frame member and with its other end pivotably fastened in a joint in the bogie element . - a first spring leg and a second spring leg , wherein each spring leg with its one end is articulately fastened to the frame member and with its other end is articulately fastened to a rocker arm . - a motion conversion arrangement capable of converting a rotary motion in a joint for one of the rocker arms to a forward and backward translation motion to accommodate changes in distance between the rocker arms' joints.
A cartridge for use in the washing and separation of a sample comprising a barrel having a barrel first end that is open and a barrel second end opposite the barrel first end; a column segment , having a column segment first end connected to the barrel second end and a column segment second end opposite the column segment first end; a column spanning the column segment, the column containing a sorbent material and having a column first end in fluid communication with the barrel second end and a column second end opposite the column first end; and a mobile phase source port at the column segment first end; wherein the sorbent material includes particles that have antibodies attached to them to selectively retain analytes, proteins attached to them to retain certain classes of antibodies, or enzymes attached to them to perform specific modifications to certain classes of molecules, said cartridge being characterized in that the mobile phase source port is configured to bypass the barrel first end and an open volume of the barrel and fluidly connect directly with the column first end. a barrel having a barrel first end that is open and a barrel second end opposite the barrel first end; a column segment , having a column segment first end connected to the barrel second end and a column segment second end opposite the column segment first end; a column spanning the column segment, the column containing a sorbent material and having a column first end in fluid communication with the barrel second end and a column second end opposite the column first end; and a mobile phase source port at the column segment first end; wherein the sorbent material includes particles that have antibodies attached to them to selectively retain analytes, proteins attached to them to retain certain classes of antibodies, or enzymes attached to them to perform specific modifications to certain classes of molecules, said cartridge being characterized in that the mobile phase source port is configured to bypass the barrel first end and an open volume of the barrel and fluidly connect directly with the column first end.