mhurhangee/patent-ind-claim-en huggingface dataset:
Holding element for a duct, comprising: a first holding part with a first frame element having a first arch-shaped area and with a first elastic damping element provided at the first frame element ; and a second holding part with a second frame element having a second arch-shaped area and with a second elastic damping element provided at the second frame element , wherein the first holding part and the second holding part are moveable relative to each other between a closed state, in which the first frame element and the second frame element together form a receiving opening for circumferentially receiving the duct and being delimited by the first and second arch-shaped areas , and an open state releasing the duct; wherein the receiving opening has a circular opening cross section; and wherein each of the first and second elastic damping elements comprises an elastic plate extending in a circumferential direction of the circular receiving opening along the corresponding arch-shaped area , characterised in that the elastic plates each have such a curvature that in the closed state of the holding element they are bulged from the corresponding arch-shaped area towards a middle axis (M) of the circular receiving opening along their whole extension in the circumferential direction of the circular receiving opening along the corresponding arch-shaped area . a first holding part with a first frame element having a first arch-shaped area and with a first elastic damping element provided at the first frame element ; and a second holding part with a second frame element having a second arch-shaped area and with a second elastic damping element provided at the second frame element , wherein the first holding part and the second holding part are moveable relative to each other between a closed state, in which the first frame element and the second frame element together form a receiving opening for circumferentially receiving the duct and being delimited by the first and second arch-shaped areas , and an open state releasing the duct; wherein the receiving opening has a circular opening cross section; and wherein each of the first and second elastic damping elements comprises an elastic plate extending in a circumferential direction of the circular receiving opening along the corresponding arch-shaped area , characterised in that the elastic plates each have such a curvature that in the closed state of the holding element they are bulged from the corresponding arch-shaped area towards a middle axis (M) of the circular receiving opening along their whole extension in the circumferential direction of the circular receiving opening along the corresponding arch-shaped area .
Guide RNA for targeted RNA editing having at least the following nucleotide segments coupled to one another, listed from the 5' terminus: - Segment A: Nucleotide sequence having a length of three to five bases, wherein a guanosine is always in position 1 and a uridine is always in position 2; - Segment B: Nucleotide sequence having a length of three to five bases, wherein an adenosine is always in position 1; - Segment C: Nucleotide sequence having a length of eight to ten bases, wherein a guanosine is always in position 1; - Segment D: Nucleotide sequence UAUGCUAAAUG or UAUGCUCAAUG; - Segment E: Nucleotide sequence having a length of eight to ten bases, wherein a guanosine is always in the ultimate position; - Segment F: Nucleotide sequence having a length of three to five bases, wherein a cytosine is always in the ultimate position; - Segment G: Nucleotide sequence having a length of three to five bases, wherein an adenosine is always in the next-to-the-ultimate position and a cytosine is in the ultimate position; - Segment H: Nucleotide sequence having a length of five to nine bases, wherein a cytosine or a uridine is always in the ultimate position; - Segment I: Nucleotide sequence having a length of eight to twenty bases, wherein individual nucleotides of the segments A and G, B and F, or C and E pair to form a double helix and the nucleotides of segment D form a hairpin structure and wherein segments H and I are designed such that they pair with the mRNA to be edited. - Segment A: Nucleotide sequence having a length of three to five bases, wherein a guanosine is always in position 1 and a uridine is always in position 2; - Segment B: Nucleotide sequence having a length of three to five bases, wherein an adenosine is always in position 1; - Segment C: Nucleotide sequence having a length of eight to ten bases, wherein a guanosine is always in position 1; - Segment D: Nucleotide sequence UAUGCUAAAUG or UAUGCUCAAUG; - Segment E: Nucleotide sequence having a length of eight to ten bases, wherein a guanosine is always in the ultimate position; - Segment F: Nucleotide sequence having a length of three to five bases, wherein a cytosine is always in the ultimate position; - Segment G: Nucleotide sequence having a length of three to five bases, wherein an adenosine is always in the next-to-the-ultimate position and a cytosine is in the ultimate position; - Segment H: Nucleotide sequence having a length of five to nine bases, wherein a cytosine or a uridine is always in the ultimate position; - Segment I: Nucleotide sequence having a length of eight to twenty bases,
A rail vehicle with a wagon body unit (102.1) supported on a running gear unit via a secondary suspension arrangement , wherein - said secondary suspension arrangement comprises a secondary suspension device and an emergency spring device (105; 205; 305), - said emergency spring device (105; 205; 305) comprising an emergency spring unit (107; 207; 307) configured to provide resilient emergency support of a wagon body unit (102.1) of a wagon body of said vehicle on said running gear unit at least in a direction of a height axis of said wagon body in an emergency operation in case of a failure of said secondary suspension device; - said emergency spring device (105; 205; 305) further comprising a decoupling unit (110; 210; 310); wherein - said decoupling unit (110; 210; 310) and said emergency spring unit (107; 207; 307) are configured to be arranged kinematically in series between said wagon body unit (102.1) and said running gear unit ; - said decoupling unit (110; 210; 310) is configured to mechanically decouple said wagon body unit (102.1) from said running gear unit about a decoupling axis of rotation (105.1) extending along a longitudinal axis of said wagon body ; characterized in that - said emergency spring device (105; 205; 305) is located substantially centrally in a transverse direction of said rail vehicle. - said secondary suspension arrangement comprises a secondary suspension device and an emergency spring device (105; 205; 305), - said emergency spring device (105; 205; 305) comprising an emergency spring unit (107; 207; 307) configured to provide resilient emergency support of a wagon body unit (102.1) of a wagon body of said vehicle on said running gear unit at least in a direction of a height axis of said wagon body in an emergency operation in case of a failure of said secondary suspension device; - said emergency spring device (105; 205; 305) further comprising a decoupling unit (110; 210; 310); wherein - said decoupling unit (110; 210; 310) and said emergency spring unit (107; 207; 307) are configured to be arranged kinematically in series between said wagon body unit (102.1) and said running gear unit ; - said decoupling unit (110; 210; 310) is configured to mechanically decouple said wagon body unit (102.1) from said running gear unit about a decoupling axis of rotation (105.1) extending along a longitudinal axis of said wagon body ; - said emergency spring device (105; 205; 305) is located substantially centrally in a transverse direction of said rail vehicle.
Spectacle lens comprising an activable optical filter, the activable optical filter being configured to be actively switched between at least three configurations, - the activable optical filter comprising a first activable element and a second activable element, - the first activable element comprising a first electrochromic dye compound in an electrochromic cell, - the second activable element comprising at least a liquid crystal formulation associated with at least a first holographic grating configured to reflect light radiations over at least one predetermined range of wavelengths when activated, - the first configuration corresponding to all activable elements being non activated, - the second configuration corresponding to the first activable element being non activated and the second activable element being activated, and - the third configuration corresponding to the first activable element being activated and the second activable element being non activated wherein - in the first configuration, the color perception of the spectacle wearer is unaltered and light transmitted through the activable optical filter has a chroma C ∗ 1 and hue h°1, - in the second configuration light transmitted through the activable optical filter has a chroma C ∗ 2 and hue h°2, - in the third configuration vision of the spectacle wearer is protected against glare and light transmitted through the activable optical filter has a chroma C ∗ 3 and hue h°3, and - the chromaticity difference Δ Chrom between (C ∗ 2, h°2) and (C ∗ 3, h°3) is larger than or equal to 20. - the activable optical filter comprising a first activable element and a second activable element, - the first activable element comprising a first electrochromic dye compound in an electrochromic cell, - the second activable element comprising at least a liquid crystal formulation associated with at least a first holographic grating configured to reflect light radiations over at least one predetermined range of wavelengths when activated, - the first configuration corresponding to all activable elements being non activated, - the second configuration corresponding to the first activable element being non activated and the second activable element being activated, and - the third configuration corresponding to the first activable element being activated and the second activable element being non activated wherein - in the first configuration, the color perception of the spectacle wearer is unaltered and light transmitted through the activable optical filter has a chroma C ∗ 1 and hue h°1, - in the second configuration light transmitted through the activable optical filter has a chroma C ∗ 2 and hue h°2, - in the third configuration vision of the spectacle wearer is protected against glare and light transmitted through the activable optical filter has a chroma C ∗ 3 and hue h°3, and - the chromaticity difference Δ Chrom between (C ∗ 2, h°2) and (C ∗ 3, h°3) is larger than or equal to 20.
A system for inducing negative pressure in a portion of a urinary tract of a patient, the system comprising: (a) a ureteral catheter comprising a distal portion for insertion within the patient's kidney and a proximal portion; (b) a bladder catheter comprising a distal portion in the patient's bladder and a proximal portion for application of negative pressure, the proximal portion extending outside the patient's body; and (c) a pump external to the patient's body for application of negative pressure at the proximal end of the bladder catheter, wherein the pump induces negative pressure through both the bladder catheter and the ureteral catheter , which in turn causes fluid from the kidney to be drawn into the ureteral catheter , through both the ureteral catheter and the bladder catheter , and then outside the patient's body. (a) a ureteral catheter comprising a distal portion for insertion within the patient's kidney and a proximal portion; (b) a bladder catheter comprising a distal portion in the patient's bladder and a proximal portion for application of negative pressure, the proximal portion extending outside the patient's body; and (c) a pump external to the patient's body for application of negative pressure at the proximal end of the bladder catheter, wherein the pump induces negative pressure through both the bladder catheter and the ureteral catheter , which in turn causes fluid from the kidney to be drawn into the ureteral catheter , through both the ureteral catheter and the bladder catheter , and then outside the patient's body.
An adhesive preparation containing bisoprolol, comprising a backing and a pressure-sensitive adhesive layer formed on one side of the backing, wherein the pressure-sensitive adhesive layer contains the following component (A) to component (C): component (A): a polymer prepared through copolymerization of monomer components including a hydroxyl group-containing monomer, an alkyl (meth)acrylate monomer, and a N-vinyl-cyclic amide monomer; component (B): a polymer prepared through copolymerization of monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and component (C): bisoprolol. component (A): a polymer prepared through copolymerization of monomer components including a hydroxyl group-containing monomer, an alkyl (meth)acrylate monomer, and a N-vinyl-cyclic amide monomer; component (B): a polymer prepared through copolymerization of monomer components including a methyl methacrylate monomer and a butyl methacrylate monomer; and component (C): bisoprolol.
A control system for electrically controlled installations, comprising at least one electronic control device for monitoring and controlling an installation and/or installation components , at least one portable, mobile manual control unit for displaying information and for inputting control commands, with an internal power supply unit for the temporary, electrical power supply of the manual control unit , a wireless communication connection between the at least one control device and the manual control unit for transmitting information and control commands between the manual control unit and the control device , wherein at least one form-flexible, material coupling means with a limited maximum longitudinal extension is provided, which coupling means is provided via at least one coupling device that can be activated without the use of tools for the optional creation and disconnection of a physical link between the manual control unit and at least one spatially fixed machine-side coupling counterpart , characterized in that at least one coupling state monitoring device is designed for the continuous detection and monitoring of a mechanical coupling state of the at least one coupling device and/or for the continuous detection and monitoring of a signaling connection state via the coupling means between the manual control unit and the at least one coupling counterpart , wherein the control system is designed for enabling the input of supervisory-relevant control commands, in particular control commands to be monitored directly by an operator on the manual control unit in case of the detection of a created coupling state or an existing connection state and for blocking the input of supervisory-relevant control commands via the manual control unit in case of the detection of a disconnected coupling state or an interrupted connection state.
A composition to protect skin against contact with metal irritants and allergens that comprises, in a cosmetically acceptable medium, at least one metal capturing agent bearing carboxyl moieties, that does not dissociate at pH 4 to 8, wherein the agent bearing carboxyl moieties is a carbomer, and wherein the composition further comprising an agent chosen among calcium carbonate, magnesium carbonate, ferric orthophosphate, ferric phosphate, ferric pyrophosphate, ferric sodium pyrophosphate, magnesium phosphate, manganese carbonate, sodium aluminum phosphate, sodium bicarbonate, ammonium carbonate, ammonium phosphate.
A circuit breaker, comprising: a first current detecting circuit that is adapted to detect a load current; a second current detecting circuit that is adapted to detect the load current; and comparison means that is adapted to compare an output signal of the first current detecting circuit and an output signal of the second current detecting circuit, characterized in that the first current detecting circuit is adapted to detect the load current using a microcomputer in accordance with a signal output from a current detecting coil ; and the second current detecting circuit is adapted to detect the load current using an output current of a power supply CT ; wherein the output current of the power supply CT of the second current detecting circuit is supplied to the microcomputer of the first current detecting circuit as a drive power supply; and wherein the circuit breaker is adapted to determine whether an operation of the microcomputer is normal or abnormal based on an output of the comparison means. a first current detecting circuit that is adapted to detect a load current; a second current detecting circuit that is adapted to detect the load current; and comparison means that is adapted to compare an output signal of the first current detecting circuit and an output signal of the second current detecting circuit, characterized in that the first current detecting circuit is adapted to detect the load current using a microcomputer in accordance with a signal output from a current detecting coil ; and the second current detecting circuit is adapted to detect the load current using an output current of a power supply CT ; wherein the output current of the power supply CT of the second current detecting circuit is supplied to the microcomputer of the first current detecting circuit as a drive power supply; and wherein the circuit breaker is adapted to determine whether an operation of the microcomputer is normal or abnormal based on an output of the comparison means.
Endodontic system comprising: - a handpiece , to which an endodontic instrument can be connected that is intended to be inserted into a root canal; - a measurement unit , located in the handpiece , for measuring at least one magnitude related to the position of the endodontic instrument in the root canal; - a computation and display unit for displaying at least one graph representing the evolution of said at least one magnitude measured by the measurement unit during an endodontic treatment, or a simulation of endodontic treatment, with the endodontic instrument , this computation and display unit being further configured to display at least one reference graph representing at least one predetermined endodontic treatment technique. - a handpiece , to which an endodontic instrument can be connected that is intended to be inserted into a root canal; - a measurement unit , located in the handpiece , for measuring at least one magnitude related to the position of the endodontic instrument in the root canal; - a computation and display unit for displaying at least one graph representing the evolution of said at least one magnitude measured by the measurement unit during an endodontic treatment, or a simulation of endodontic treatment, with the endodontic instrument , this computation and display unit being further configured to display at least one reference graph representing at least one predetermined endodontic treatment technique.
A bearing assembly , comprising: a first plurality of superhard bearing elements distributed about an axis, each of the first plurality of superhard bearing elements having a substrate bonded to a superhard table comprising a superhard material including a superhard bearing surface ; and a support ring structure coupled to the first plurality of superhard bearing elements ; characterised in that the superhard material of at least some of the first plurality of superhard bearing elements exhibits a maximum thickness that is greater than 7,62 mm (0.3 inch). a first plurality of superhard bearing elements distributed about an axis, each of the first plurality of superhard bearing elements having a substrate bonded to a superhard table comprising a superhard material including a superhard bearing surface ; and a support ring structure coupled to the first plurality of superhard bearing elements ; characterised in that the superhard material of at least some of the first plurality of superhard bearing elements exhibits a maximum thickness that is greater than 7,62 mm (0.3 inch).
A method for producing a shaped article, the method comprising: a) providing a binder, wherein the binder has been produced by a process of: i) mixing (A) fungi or beta glucan and (B) starch with an alkaline agent to form an alkaline composition; and mixing the alkaline composition with an acidic agent to form the binder, or ii) mixing (A) fungi or beta glucan and (B) starch with an acidic agent to form an acidic composition; and mixing the acidic composition with an alkaline agent to form the binder; b) forming a binder composition by mixing the binder with filler material; c) shaping the binder composition into a three-dimensional shape; and d) curing the binder composition to form a shaped article having said three-dimensional shape; wherein step c) and step d) can be carried out simultaneously or separately, wherein during one or both of step c) and step d) pressure is applied to the binder composition, and wherein the starch is selected from the group consisting of: amylose, amylopectin, modified starches, cationic starches, carboxymethyl starches, oxidised starches, bleached starches, monostarch phosphates, distarch phosphates, acetylated starches and hydroxypropyl starches. a) providing a binder, wherein the binder has been produced by a process of: i) mixing (A) fungi or beta glucan and (B) starch with an alkaline agent to form an alkaline composition; and mixing the alkaline composition with an acidic agent to form the binder, or ii) mixing (A) fungi or beta glucan and (B) starch with an acidic agent to form an acidic composition; and mixing the acidic composition with an alkaline agent to form the binder; i) mixing (A) fungi or beta glucan and (B) starch with an alkaline agent to form an alkaline composition; and mixing the alkaline composition with an acidic agent to form the binder, or ii) mixing (A) fungi or beta glucan and (B) starch with an acidic agent to form an acidic composition; and mixing the acidic composition with an alkaline agent to form the binder; b) forming a binder composition by mixing the binder with filler material; c) shaping the binder composition into a three-dimensional shape; and d) curing the binder composition to form a shaped article having said three-dimensional shape; wherein step c) and step d) can be carried out simultaneously or separately, wherein during one or both of step c) and step d) pressure is applied to the binder composition, and wherein the starch is selected from the group consisting of: amylose, amylopectin, modified starches, cationic starches, carboxymethyl starches, oxidised starches, bleached starches, monostarch phosphates, distarch phosphates, acetylated starches and hydroxypropyl starches.
A monitoring device with a safety sensor, by means of which objects can be detected within a protective field , wherein the safety sensor triggers a safety function in normal operation when it registers an object intrusion in the protective field , wherein a bridging unit and detection means, by means of which an object moving towards the safety sensor can be detected successively at at least two detection points , are present, and wherein at least one region of the protective field is provided, by means of which an object moving towards the safety sensor can be detected successively at at least two detection points , and wherein at least one region of the protective field of the safety sensor is bridged by the bridging unit only if the object is detected within a predetermined time interval, if an object intrusion is registered at the detection points within a predetermined time interval, the safety sensor not triggering a safety function in the event of an object intrusion in the bridged area of the protective field , characterised in that the bridging unit transfers the safety sensor into a safe locking state if, after an object intrusion at a first detection point , no object intrusion is registered at the second detection point within the predetermined time interval.