mhurhangee/patent-ind-claim-en huggingface dataset:
Drilling head for a drill bit having a top side for breaking down mineral material, a bottom side for fastening to a shaft of the drill bit , an axis of rotation , which runs centrally through the top side and the bottom side , arms , which each have a proximal end with respect to the axis of rotation and a distal end with respect to the axis of rotation , and wherein the top sides of the arms have primary chisel edges each running from the proximal end to the distal end , wherein at least one of the arms on the top side has a secondary chisel edge running alongside the primary chisel edge , wherein the secondary chisel edge is offset from the primary chisel edge of the same arm towards the front in a rotational direction of the drilling head , characterized in that the primary chisel edge and the secondary chisel edge between them delimit a channel on the top side of the arm , and in that the primary chisel edge continuously protrudes beyond the second chisel edge of the same arm in the impact direction . a top side for breaking down mineral material, a bottom side for fastening to a shaft of the drill bit , an axis of rotation , which runs centrally through the top side and the bottom side , arms , which each have a proximal end with respect to the axis of rotation and a distal end with respect to the axis of rotation , and wherein the top sides of the arms have primary chisel edges each running from the proximal end to the distal end , wherein at least one of the arms on the top side has a secondary chisel edge running alongside the primary chisel edge , wherein the secondary chisel edge is offset from the primary chisel edge of the same arm towards the front in a rotational direction of the drilling head , characterized in that the primary chisel edge and the secondary chisel edge between them delimit a channel on the top side of the arm , and in that the primary chisel edge continuously protrudes beyond the second chisel edge of the same arm in the impact direction .
An antibody having the ability of binding to CLD18A2 and mediating killing of cells expressing CLD18A2, wherein said antibody comprises a heavy chain variable domain (VH) and a light chain variable domain (VL) comprising a set of complementarity-determining regions CDR1, CDR2 and CDR3 selected from the following sets (i) to (v): (i) VH: CDR1: positions 45-52 of SEQ ID NO: 115, CDR2: positions 70-77 of SEQ ID NO: 115, CDR3: positions 116-125 of SEQ ID NO: 115, VL: CDR1: positions 49-53 of SEQ ID NO: 122, CDR2: positions 71-73 of SEQ ID NO: 122, CDR3: positions 110-118 of SEQ ID NO: 122, (ii) VH: CDR1: positions 45-52 of SEQ ID NO: 116, CDR2: positions 70-77 of SEQ ID NO: 116, CDR3: positions 116-126 of SEQ ID NO: 116, VL: CDR1: positions 47-58 of SEQ ID NO: 121, CDR2: positions 76-78 of SEQ ID NO: 121, CDR3: positions 115-123 of SEQ ID NO: 121, (iii) VH: CDR1: positions 45-52 of SEQ ID NO: 117, CDR2: positions 70-77 of SEQ ID NO: 117, CDR3: positions 116-124 of SEQ ID NO: 117, VL: CDR1: positions 47-52 of SEQ ID NO: 123, CDR2: positions 70-72 of SEQ ID NO: 123, CDR3: positions 109-117 of SEQ ID NO: 123, (iv) VH: CDR1: positions 44-51 of SEQ ID NO: 119, CDR2: positions 69-76 of SEQ ID NO: 119, CDR3: positions 115-125 of SEQ ID NO: 119, VL: CDR1: positions 47-58 of SEQ ID NO: 126, CDR2: positions 76-78 of SEQ ID NO: 126, CDR3: positions 115-122 of SEQ ID NO: 126, and (v) VH: CDR1: positions 45-52 of SEQ ID NO: 118, CDR2: positions 70-77 of SEQ ID NO: 118, CDR3: positions 116-126 of SEQ ID NO: 118, VL: CDR1: positions 47-58 of SEQ ID NO: 125, CDR2: positions 76-78 of SEQ ID NO: 125, CDR3: positions 115-123 of SEQ ID NO: 125, wherein the VH and VL domains of the antibody are expressed on a single polypeptide chain. (i) VH: CDR1: positions 45-52 of SEQ ID NO: 115, CDR2: positions 70-77 of SEQ ID NO: 115, CDR3: positions 116-125 of SEQ ID NO: 115, VL: CDR1: positions 49-53 of SEQ ID NO: 122, CDR2: positions 71-73 of SEQ ID NO: 122, CDR3: positions 110-118 of SEQ ID NO: 122, (ii) VH: CDR1: positions 45-52 of SEQ ID NO: 116, CDR2: positions 70-77 of SEQ ID NO: 116, CDR3: positions 116-126 of SEQ ID NO: 116, VL: CDR1: positions 47-58 of SEQ ID NO: 121, CDR2: positions 76-78 of SEQ ID NO: 121, CDR3: positions 115-123 of SEQ ID NO: 121, (iii) VH: CDR1: positions 45-52 of SEQ ID NO: 117, CDR2: positions 70-77 of SEQ ID NO: 117, CDR3: positions 116-124 of SEQ ID NO: 117, VL: CDR1: positions 47-52 of SEQ ID NO: 123, CDR2: positions 70-72 of SEQ ID NO: 123, CDR3: positions 109-117 of SEQ ID NO: 123, (iv) VH: CDR1: positions 44-51 of SEQ ID NO: 119, CDR2: positions 69-76 of SEQ ID NO: 119, CDR3: positions 115-125 of SEQ ID NO: 119, VL: CDR1: positions 47-58 of SEQ ID NO: 126, CDR2: positions 76-78 of SEQ ID NO: 126, CDR3: positions 115-122 of SEQ ID NO: 126, and (v) VH: CDR1: positions 45-52 of SEQ ID NO: 118, CDR2: positions 70-77 of SEQ ID NO: 118, CDR3: positions 116-126 of SEQ ID NO: 118, VL: CDR1: positions 47-58 of SEQ ID NO: 125, CDR2: positions 76-78 of SEQ ID NO: 125, CDR3: positions 115-123 of SEQ ID NO: 125,
A pharmaceutical composition comprising: a SHIP inhibitor compound of formula (I), or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier; wherein formula (I) is as follows: wherein R 1 is a straight chain C 1 -C 4 alkyl or C 1 -C 4 haloalkyl; R 2 is hydrogen, methyl, or halomethyl; R 3 is hydrogen, substituted or unsubstituted amino, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, or C 1 -C 4 alkenyl; R 4 is hydrogen, substituted or unsubstituted amino, C 1 -C 4 alkyl, or benzyl; R 5 represents one hydrogen atom together with an alkyl group; R 13 is either absent or hydrogen; X 1 is selected from the group consisting of hydrogen, mercapto alkylthio, arylthio, alkylcarbonamido, arylcarbonamido, aryloxycarbonamido, arylsulfonamido, (C 1 -C 4 alkyl)carbonyloxy, (C 1 -C 4 alkoxy)carbonyloxy, aryloxycarbonyloxy, a secondary or tertiary amino group that includes at least one C 1 -C 4 alkyl, C 5 -C 6 cycloalkyl, aryl, or heterocyclic substituent, or combinations thereof, unsubstituted amino, and aminoalkyl; and each X 2 individually represents two hydrogen atoms; with the proviso that X 1 cannot be a primary amino group when: R 1 and R 2 are each methyl; X 2 , R 3 , R 4 , and R 13 are each hydrogen; and R 5 represents one hydrogen atom together with a 1, 5-dimethylhexyl alkyl group. a pharmaceutically acceptable carrier; wherein formula (I) is as follows: R 1 is a straight chain C 1 -C 4 alkyl or C 1 -C 4 haloalkyl; R 2 is hydrogen, methyl, or halomethyl; R 3 is hydrogen, substituted or unsubstituted amino, C 1 -C 4 alkyl, C 1 -C 4 haloalkyl, or C 1 -C 4 alkenyl; R 4 is hydrogen, substituted or unsubstituted amino, C 1 -C 4 alkyl, or benzyl; R 5 represents one hydrogen atom together with an alkyl group; R 13 is either absent or hydrogen; X 1 is selected from the group consisting of hydrogen, mercapto alkylthio, arylthio, alkylcarbonamido, arylcarbonamido, aryloxycarbonamido, arylsulfonamido, (C 1 -C 4 alkyl)carbonyloxy, (C 1 -C 4 alkoxy)carbonyloxy, aryloxycarbonyloxy, a secondary or tertiary amino group that includes at least one C 1 -C 4 alkyl, C 5 -C 6 cycloalkyl, aryl, or heterocyclic substituent, or combinations thereof, unsubstituted amino, and aminoalkyl; and each X 2 individually represents two hydrogen atoms; with the proviso that X 1 cannot be a primary amino group when: R 1 and R 2 are each methyl; X 2 , R 3 , R 4 , and R 13 are each hydrogen; and R 5 represents one hydrogen atom together with a 1, 5-dimethylhexyl alkyl group.
A dental cleaning tool comprising: a body portion defining a longitudinal axis of the dental cleaning tool, wherein the body portion comprises: a floss assembly comprising a first arm and a second arm extending substantially perpendicularly relative to the longitudinal axis; and a secondary cleaning tool coupled to the first arm; the dental cleaning tool being characterised by : a receiving slot formed in the first arm ; and a shield formed on the first arm , wherein the shield is configured to cover the receiving slot such that access to the receiving slot is restricted from a first direction ; wherein the secondary cleaning tool is pivotable relative to the first arm in at least two degrees of freedom such that the secondary cleaning tool is insertable into the receiving slot from a second direction different than the first direction. a body portion defining a longitudinal axis of the dental cleaning tool, wherein the body portion comprises: a floss assembly comprising a first arm and a second arm extending substantially perpendicularly relative to the longitudinal axis; and a secondary cleaning tool coupled to the first arm; a floss assembly comprising a first arm and a second arm extending substantially perpendicularly relative to the longitudinal axis; and a secondary cleaning tool coupled to the first arm; the dental cleaning tool being characterised by : a receiving slot formed in the first arm ; and a shield formed on the first arm , wherein the shield is configured to cover the receiving slot such that access to the receiving slot is restricted from a first direction ; a receiving slot formed in the first arm ; and a shield formed on the first arm , wherein the shield is configured to cover the receiving slot such that access to the receiving slot is restricted from a first direction ; wherein the secondary cleaning tool is pivotable relative to the first arm in at least two degrees of freedom such that the secondary cleaning tool is insertable into the receiving slot from a second direction different than the first direction.
An external urinary incontinence control apparatus , comprising: a semi-cylindrical dorsal hood defining a semi-cylindrical channel and having an exterior surface, an interior surface facing the semi-cylindrical channel , and at least one fenestration ; a urethral compressor ; a strap interconnecting the dorsal hood and the urethral compressor and such that the urethral compressor is retained caudad to the dorsal hood , characterized in that the urethral compressor includes a ridge facing the semi-cylindrical channel and extending transverse to a longitudinal axis of the dorsal hood , said longitudinal axis extending in the direction defined by the urethra; and the urethral compressor includes a main body and a first loop at a first end of the main body and a second loop at a second end of the main body , the second end of the main body being opposite to the first end of the main body in a direction transverse to the longitudinal axis, wherein each loop defines a space between the respective loop and the main body. a semi-cylindrical dorsal hood defining a semi-cylindrical channel and having an exterior surface, an interior surface facing the semi-cylindrical channel , and at least one fenestration ; a urethral compressor ; a strap interconnecting the dorsal hood and the urethral compressor and such that the urethral compressor is retained caudad to the dorsal hood , characterized in that the urethral compressor includes a ridge facing the semi-cylindrical channel and extending transverse to a longitudinal axis of the dorsal hood , said longitudinal axis extending in the direction defined by the urethra; and the urethral compressor includes a main body and a first loop at a first end of the main body and a second loop at a second end of the main body , the second end of the main body being opposite to the first end of the main body in a direction transverse to the longitudinal axis, wherein each loop defines a space between the respective loop and the main body.
Loom for weaving seamless closed edge multilayer fabrics (30; 70), wherein a shuttle (50; 60; 100, 200) carrying a shuttlespool with weft thread (51; 61) for inserting the weft thread in between warp threads is arranged to operate a right and left translation along a first operating trajectory extending between the warp threads through a first shed and a a second operating trajectory, distinct from the first operating trajectory, extending between the warp threads through a second shed .
A packed column (11; 31) which includes a gas-liquid contactor (17, 18; 33a, 33b, 34) inside a tubular body (16; 32) and a liquid distributor (19; 35a) in an uppermost portion and causes descending liquid and ascending gas to contact each other in the gas-liquid contactor (17, 18; 33a, 33b, 34), wherein operation pressure is in a range of 200 to 1500 kPaG, relative volatility is in a range of 1.9 to 3.1, the gas-liquid contactor is horizontally divided into at least two parts to thereby form a plurality of gas-liquid contactors (17, 18; 33a, 33b, 34), wherein: two or more gas dispersers (20; 36) is-are each provided between a lower one (18; 34) of the gas-liquid contactors and an upper one (17; 33a) of the gas-liquid contactors, the gas dispersers uniformly dispersing composition of the ascending gas rising from the respective lower gas-liquid contactor toward the respective upper gas-liquid contactor , characterised in that a total height of the gas-liquid contactors (17; 33a, 33b) above the highest gas disperser (20; 36) of the two or more gas dispersers is set such that a ratio of the total height to a height of all the gas-liquid contactors (17, 18; 33a, 33b, 34) is 0.5 or greater, in particular 0.7 or greater. operation pressure is in a range of 200 to 1500 kPaG, relative volatility is in a range of 1.9 to 3.1, the gas-liquid contactor is horizontally divided into at least two parts to thereby form a plurality of gas-liquid contactors (17, 18; 33a, 33b, 34), wherein: two or more gas dispersers (20; 36) is-are each provided between a lower one (18; 34) of the gas-liquid contactors and an upper one (17; 33a) of the gas-liquid contactors, the gas dispersers uniformly dispersing composition of the ascending gas rising from the respective lower gas-liquid contactor toward the respective upper gas-liquid contactor , characterised in that a total height of the gas-liquid contactors (17; 33a, 33b) above the highest gas disperser (20; 36) of the two or more gas dispersers is set such that a ratio of the total height to a height of all the gas-liquid contactors (17, 18; 33a, 33b, 34) is 0.5 or greater, in particular 0.7 or greater.
A spring (10; 20) for a horological mechanism, the spring comprising a body (11; 21) extending between a first end (12; 22) of the spring and a second end (13; 23) of the spring, the spring being intended to be connected mechanically to a frame at each of the first and second ends, the spring comprising, between the first and the second end, at least one member (17; 27) intended to act by contact on an element (42; 52) of the horological mechanism, the body comprising a deformable zone (14; 24) extending in a curve (18; 28), the curve comprising a first part (18a; 28a) that is concave when viewed from the first end, the member comprising a lever, the lever extending along a half-line (191; 291) lying in a half-plane complementary to the half-plane in which part of the deformable zone deformable zone extends along the concave part (18a; 28a) of the curve (18; 28) from one end of the spring, the half-planes being separated by a straight line (D1) passing through the axes of the mechanical links connecting the spring to the frame, wherein the spring is intended to be mechanically connected to a frame via a pivot link at each of the first and second ends and wherein the lever (17 ; 27) pivotes about an axis (19; 29) of the pivot link mechanically connecting the spring to the frame and located at the first end.
A stent graft device comprising: an expandable support frame having incorporated therein an anchoring member to anchor said stent graft device in a lumen; and a covering extending over said expandable support frame , wherein a geometry of said anchoring member changes for removal of said anchoring member from tissue growth over said anchoring member , wherein said anchoring member is a coiled wire extending outwardly from said expandable support frame in an implanted state, and wherein said anchoring member assumes an uncoiled configuration for removal of said stent graft device from said lumen. an expandable support frame having incorporated therein an anchoring member to anchor said stent graft device in a lumen; and a covering extending over said expandable support frame , wherein a geometry of said anchoring member changes for removal of said anchoring member from tissue growth over said anchoring member , wherein said anchoring member is a coiled wire extending outwardly from said expandable support frame in an implanted state, and wherein said anchoring member assumes an uncoiled configuration for removal of said stent graft device from said lumen.
A system for controlling admission of a compressible fluid to an electromechanical component mounted on a wheel of a vehicle , the system comprising: a first plurality of float valves arranged in series in a first flowpath , with at least one of the float valves forming an inlet for intaking the compressible fluid into the first flowpath , and one being in communication with an inlet of the electromechanical component ; and characterized in that each of the float valves having a buoyant float valve element (506a1) therein responsive to change position when submerged in water, to close off its respective said float valve depending on an angular orientation of said wheel , and thus an angular orientation of said float valve . a first plurality of float valves arranged in series in a first flowpath , with at least one of the float valves forming an inlet for intaking the compressible fluid into the first flowpath , and one being in communication with an inlet of the electromechanical component ; and characterized in that each of the float valves having a buoyant float valve element (506a1) therein responsive to change position when submerged in water, to close off its respective said float valve depending on an angular orientation of said wheel , and thus an angular orientation of said float valve .
A composition, comprising: (Z)-1-chloro-2,3,3-trifluoro-1-propene; (E)-1 -chloro-2,3,3-trifluoro-1 -propene; and water, wherein a proportion of (Z)-1-chloro-2,3,3-trifluoro-1-propene with respect to a sum total of contents of the (Z)-1-chloro-2,3,3-trifluoro-1-propene, (E)-1-chloro-2,3,3-trifluoro-1-propene and water is 90 mass% or more. (Z)-1-chloro-2,3,3-trifluoro-1-propene; (E)-1 -chloro-2,3,3-trifluoro-1 -propene; and water, wherein a proportion of (Z)-1-chloro-2,3,3-trifluoro-1-propene with respect to a sum total of contents of the (Z)-1-chloro-2,3,3-trifluoro-1-propene, (E)-1-chloro-2,3,3-trifluoro-1-propene and water is 90 mass% or more.
An apparatus for estimating bio-information of a user, the apparatus comprising: a sensor part comprising a contact pressure sensor array configured to obtain a contact pressure distribution of a contact surface contacted by a user's object, an image sensor configured to obtain a contact image of the object that contacts the contact surface, and a display panel provided between the contact pressure sensor array and the image sensor , wherein the image sensor includes a pixel array, each pixel of the pixel array including a detector for detecting light which is emitted from the display panel and is reflected or scattered from the object, converting the detected light into an electric signal and outputting electric signal as contact image data; and a processor configured to divide the contact image into one or more regions, obtain a pulse wave signal from each of said one or more regions of the contact image by using the contact image data, and select a pulse wave signal of a region of interest among the obtained pulse wave signals of each region based on a contact pressure at a position corresponding to each of the one or more regions in the contact pressure distribution, wherein the processor is further configured to estimate bio-information based on contact pressure at a position corresponding to the region of interest in the contact pressure distribution, and the selected pulse wave signal. a sensor part comprising a contact pressure sensor array configured to obtain a contact pressure distribution of a contact surface contacted by a user's object, an image sensor configured to obtain a contact image of the object that contacts the contact surface, and a display panel provided between the contact pressure sensor array and the image sensor , wherein the image sensor includes a pixel array, each pixel of the pixel array including a detector for detecting light which is emitted from the display panel and is reflected or scattered from the object, converting the detected light into an electric signal and outputting electric signal as contact image data; and a processor configured to divide the contact image into one or more regions, obtain a pulse wave signal from each of said one or more regions of the contact image by using the contact image data, and select a pulse wave signal of a region of interest among the obtained pulse wave signals of each region based on a contact pressure at a position corresponding to each of the one or more regions in the contact pressure distribution, wherein the processor is further configured to estimate bio-information based on contact pressure at a position corresponding to the region of interest in the contact pressure distribution, and the selected pulse wave signal.
A laminate comprising a layer and a layer on at least one surface of the layer , at least one layer of outermost layers being the layer , the laminate having a laminated structure with three or more layers, wherein both the layer and the layer contain a plasticizer A and a plasticizer B, wherein the layer further contains a thermoplastic resin (I), wherein the layer further contains a thermoplastic resin (II) and contains 4 to 200 parts by mass of the plasticizer A with respect to 100 parts by mass of the thermoplastic resin (II), wherein a hydroxyl value of the plasticizer A is designated as HV(A) mgKOH/g and wherein HV(A) ≥ 30, wherein a hydroxyl value of the plasticizer B is designated as HV(B) mgKOH/g and wherein HV(B) < 30, wherein a mass ratio of the plasticizer B to the plasticizer A (a content of the plasticizer B/a content of the plasticizer A) in the layer is designated as R1 and a mass ratio of the plasticizer B to the plasticizer A (a content of the plasticizer B/a content of the plasticizer A) in the layer is designated as R2 and wherein R1 > R2, and wherein the thermoplastic resin (I) is a polyvinyl acetal and the thermoplastic resin (II) is a polyvinyl acetal , and |H -H |, which is an absolute value of a difference between an average amount of a residual hydroxyl group H of the polyvinyl acetal and an average amount of a residual hydroxyl group H of the polyvinyl acetal , is 10 mol% or less.