Discharger , for discharging a predetermined amount of a substance comprising at least two components , the discharger comprising - a housing defining a longitudinal axis and having a proximal end and a distal end , - an element arranged at least partly inside said housing , - a hollow cylindrical container arranged at least partly inside said housing , said container surrounding said element at least partly and being axially movable relative to said element between a first and a second position, - at least one first compartment defined within said housing between the distal end of said element and the distal end of said housing for receiving at least one first component of said components , - at least one second compartment defined within said container assuming its first position between the proximal end of said container and the proximal end of said element for receiving at least one second component of said components , - an axially extending passage provided in the interior of said element and being in communication with said first compartment and at least one peripheral opening of said element in the region of the proximal end of said element , - sealing means for preventing communication between said second compartment and said peripheral opening of sad element when the container assumes its first position, and said discharger further being adapted so that communication between said second compartment and said peripheral opening of said element is established after initiation of the movement of said container out of its first position towards its second position relative to said element , thereby transferring said second component from said second compartment into the peripheral opening and through the passage of the element into said first compartment , characterized in that the discharger is a syringe, the element is a piston and is axially movable relative to the housing between a first and a second position, the first compartment is defined within said housing between the distal end of the piston and the distal end of said housing when the piston assumes its first position, wherein the discharger comprises releasable retaining means for retaining said piston in its first position until said container has reached its second position, said retaining means are released by said container reaching its second position, and in that with the further movement of said container into said housing and the simultaneous movement of the released piston out of its first position towards its second position, the at least two components are pressed out of said first compartment through the distal end of said housing . - a housing defining a longitudinal axis and having a proximal end and a distal end , - an element arranged at least partly inside said housing , - a hollow cylindrical container arranged at least partly inside said housing , said container surrounding said element at least partly and being axially movable relative to said element between a first and a second position, - at least one first compartment defined within said housing between the distal end of said element and the distal end of said housing for receiving at least one first component of said components , - at least one second compartment defined within said container assuming its first position between the proximal end of said container and the proximal end of said element for receiving at least one second component of said components , - an axially extending passage provided in the interior of said element and being in communication with said first compartment and at least one peripheral opening of said element in the region of the proximal end of said element , - sealing means for preventing communication between said second compartment and said peripheral opening of sad element when the container assumes its first position, and <EOS>