mhurhangee/patent-ind-claim-en huggingface dataset:
A semiconductor device having a field effect transistor, comprising: a channel layer having a first nitride semiconductor layer, an electron supply layer formed over the channel layer and having a second nitride semiconductor layer having a band gap different from that of the first nitride semiconductor layer, a source electrode formed over the electron supply layer, a drain electrode formed over the electron supply layer while being separated from the source electrode, a cap layer having a p type semiconductor layer, formed over the electron supply layer between the source electrode and the drain electrode, and having an inclined side surface, an insulating film having an opening on the upper surface of the cap layer and covering the side surface of the cap layer, and a gate electrode formed in the opening portion and extending over the side surface of the cap layer on the side of the drain electrode via the insulating film, wherein an angle θ between the upper surface of the electron supply layer and the side surface of the cap layer falls within the following range: 15°≤θ<90°. a channel layer having a first nitride semiconductor layer, an electron supply layer formed over the channel layer and having a second nitride semiconductor layer having a band gap different from that of the first nitride semiconductor layer, a source electrode formed over the electron supply layer, a drain electrode formed over the electron supply layer while being separated from the source electrode, a cap layer having a p type semiconductor layer, formed over the electron supply layer between the source electrode and the drain electrode, and having an inclined side surface, an insulating film having an opening on the upper surface of the cap layer and covering the side surface of the cap layer, and a gate electrode formed in the opening portion and extending over the side surface of the cap layer on the side of the drain electrode via the insulating film, wherein an angle θ between the upper surface of the electron supply layer and the side surface of the cap layer falls within the following range: 15°≤θ<90°.
A compound of formula (I), or a pharmaceutically acceptable salt thereof: wherein, R 1 is selected from the group consisting of COOH, or a salt thereof, C(O)NR 9 R 10 , C(O)OR 11 wherein R 9 , R 10 and R 11 are independently selected from the group consisting of hydrogen and optionally substituted C 1 -C 6 alkyl; R 3 is selected from the group consisting of optionally substituted N-linked tetrazole, optionally substituted N-linked indole, optionally substituted N-linked isoindole, optionally substituted N-linked benzotriazole, and N-linked triazole selected from the group consisting of: and R 4 is NHC(O)R 17 wherein R 17 is selected from the group consisting of C 1 -C 6 alkyl, C 1 -C 6 haloalkyl and C 3 -C 6 cycloalkyl; R 6 , R 7 and R 8 are independently selected from the group consisting of OH, NH 2 , C 1 -C 6 alkyl, NR 18 R 18 ', C 1 -C 6 alkoxy, -OC(O)R 18 , -NH(C=O)R 18 , and S(O) n R 18 , wherein n = 0 - 2 and each R 18 and R 18 ' are independently hydrogen or optionally substituted C 1 -C 6 alkyl; wherein "optionally substituted" means optional substitution with one or more groups selected from C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, CN, OH, oxo, NH 2 , Cl, F, Br, I, aryl and heterocyclyl which latter two may themselves be optionally substituted. R 1 is selected from the group consisting of COOH, or a salt thereof, C(O)NR 9 R 10 , C(O)OR 11 wherein R 9 , R 10 and R 11 are independently selected from the group consisting of hydrogen and optionally substituted C 1 -C 6 alkyl; R 3 is selected from the group consisting of optionally substituted N-linked tetrazole, optionally substituted N-linked indole, optionally substituted N-linked isoindole, optionally substituted N-linked benzotriazole, and N-linked triazole selected from the group consisting of: and R 4 is NHC(O)R 17 wherein R 17 is selected from the group consisting of C 1 -C 6 alkyl, C 1 -C 6 haloalkyl and C 3 -C 6 cycloalkyl; R 6 , R 7 and R 8 are independently selected from the group consisting of OH, NH 2 , C 1 -C 6 alkyl, NR 18 R 18 ', C 1 -C 6 alkoxy, -OC(O)R 18 , -NH(C=O)R 18 , and S(O) n R 18 , wherein n = 0 - 2 and each R 18 and R 18 ' are independently hydrogen or optionally substituted C 1 -C 6 alkyl; wherein "optionally substituted" means optional substitution with one or more groups selected from C 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 1 -C 6 alkoxy, CN, OH, oxo, NH 2 , Cl, F, Br, I, aryl and heterocyclyl which latter two may themselves be optionally substituted.
A container comprising first and second portions , each portion comprising a tubular side wall having first end and a second end , the first end being closed by an end wall, the second end being adapted to detachably engage the second end of the other portion, said first portion being arranged to store a consumable and the second portion comprising a vessel being arranged to store a fluid, wherein an aperture is formed in the tubular side wall of the first portion through which the consumable can be dispensed from the first portion characterised in that the tubular side wall of the second portion comprises at least a deformable region arranged to deform responsive to pressure to enable the fluid to be dispensed through an outlet in the second portion , an end wall of the second portion forming a detachable closure for said outlet , the second end of the tubular side wall of the first portion being open to permit said consumable to be inserted into the first portion when the first and second portions are detached.
An isolated peptide comprising the amino acid sequence in SEQ ID NO. 66 (Ile-Asp-Gln-Gln-Val-Leu-Ser-Arg-Ile-Lys-Leu-Glu-Ile-Lys-Arg-Cys-Leu) for use in a method of reducing the incidence of clinically detected prostate cancer in a mammal comprising administering a therapeutically effective amount of the isolated peptide to the mammal, wherein the peptide is administered to the central part of the prostate where cancer is less common, and the method reduces the incidence of clinically detected prostate cancer by an amount greater than 15% compared to administration of a placebo to mammals susceptible to developing prostate cancer.
An electrical energy generator array (8; 68), arranged to generate electricity from at least one form of natural flow, the electrical energy generator array (8; 68) having a drive shaft (2; 62) driven by energy from a natural energy flow and connected to a drive mechanism (2; 62), the electrical energy generator array (8; 68) further comprising an integrated electric motor (20; 80) and a plurality of individual generators (6; 66) disengageably connected to the drive mechanism, the individual generators (6; 66) being arranged on support shaft (14; 74) different from the drive shaft and connected via a series of rigid ties (4; 64) to form a connected generator array (8; 68), the array being rotated by the drive mechanism when connected to the drive mechanism (2; 62), or by the integrated electric motor when disconnected from the drive mechanism (2; 62), to generate electricity and wherein each individual generator (6; 66) comprises a rotor (10; 70) and a stator (12; 72) and the series of rigid ties (4; 64) connect the rotors (10; 70) to each other.
A ram blade of a blowout preventer for shearing structures positioned in a bore extending through the blowout preventer , the ram blade comprising at least one flat side , characterised in that the ram blade comprises: a blunt leading contour at a distal end of the ram blade , at least one upper inclined surface above the blunt leading contour , wherein the at least one upper inclined surface forms an angle between about 120 and 160 degrees with the flat side, and at least one lower declined surface below the blunt leading contour , wherein the at least one lower declined surface forms an angle between about 60 and 100 degrees with the at least one upper inclined surface . a blunt leading contour at a distal end of the ram blade , at least one upper inclined surface above the blunt leading contour , wherein the at least one upper inclined surface forms an angle between about 120 and 160 degrees with the flat side, and at least one lower declined surface below the blunt leading contour , wherein the at least one lower declined surface forms an angle between about 60 and 100 degrees with the at least one upper inclined surface .
A medical instrument system comprising an instrument manipulator configured to control a position of a medical instrument with respect to a base , the instrument manipulator comprising: an instrument carriage comprising a medical instrument connector configured to engage the medical instrument, the instrument carriage configured to translate along a linear axis (A) to advance or retract the medical instrument with respect to the base ; an insertion stage configured to telescope within the instrument carriage along the linear axis (A), the insertion stage having a drive assembly comprising a drive belt and a drive motor configured to drive the drive belt, wherein the base is fixedly coupled to the drive belt; and a connecting element having a distal end fixedly coupled to the drive belt and a proximal end fixed to the instrument carriage . an instrument carriage comprising a medical instrument connector configured to engage the medical instrument, the instrument carriage configured to translate along a linear axis (A) to advance or retract the medical instrument with respect to the base ; an insertion stage configured to telescope within the instrument carriage along the linear axis (A), the insertion stage having a drive assembly comprising a drive belt and a drive motor configured to drive the drive belt, wherein the base is fixedly coupled to the drive belt; and a connecting element having a distal end fixedly coupled to the drive belt and a proximal end fixed to the instrument carriage .
Vehicle , preferably an agricultural vehicle, such as a spreader for delivering spreadable materials, such as manure, comprising a truck box and a hydraulic system , comprising - means for connecting to a hydraulic pump , - a hydraulic motor for driving a propulsion device arranged in the bottom of the truck box , which comprises at least one bottom chain with associated idler wheels and chain tensioning device for tensioning the bottom chain through an essentially linear displacement of at least one of the idler wheels , - one or more hydraulic cylinders , which form part of the chain tensioning device , and which with a piston movement in one direction causes the chain to tension, wherein the vehicle has a first operating mode, in which the bottom chain has a first direction of operation and a second operating mode, in which the bottom chain has a second direction of operation , which is counter to the first direction of operation , characterised in that, the hydraulic cylinders have a first effective piston area in the first operating mode, the hydraulic cylinders have a second effective piston area in the second operating mode, and that the first and second effective piston area are different from each other. - means for connecting to a hydraulic pump , - a hydraulic motor for driving a propulsion device arranged in the bottom of the truck box , which comprises at least one bottom chain with associated idler wheels and chain tensioning device for tensioning the bottom chain through an essentially linear displacement of at least one of the idler wheels , - one or more hydraulic cylinders , which form part of the chain tensioning device , and which with a piston movement in one direction causes the chain to tension, wherein the vehicle has a first operating mode, in which the bottom chain has a first direction of operation and a second operating mode, in which the bottom chain has a second direction of operation , which is counter to the first direction of operation ,
A preparation method of a polyester dipped cord fabric with low denier and high modulus, the method including the following steps: 1) spinning, reducing melt discharge volume for extruding yarn with denier of 500~1000D (555,55 to 1111,11 dTex) ; using high-speed motor and heat roller, and spinning speed of 6000~6500 m/min to produce raw yarn; wherein the raw yarn has a modulus of 105 to 120 mN/dTex and a strength of 9.0 to 9.5 g/d (9,99 to 10,54 g/dTex); 2) twisting yarn, performing initial and repeat twisting of the raw yarn by a straight twisting machine to produce cords; 3) weaving, performing weaving of the cords by using a Dornier air-jet loom to produce a cord fabric; and when reeding, feeding two cords into each dent of the reed, and at the same time using a creel having a creel roller bearing and creel single spindle tension control belt to control a tension of the cords and thereby improve uniformity of the fabric; 4) dipping, performing dipping of the cord fabric using two-bath dipping method, pretreating the cord fabric in six ovens in a successive manner and then dipping the cord fabric in glue grooves, wherein each oven has a different temperature and a tension zone is provided in five of said ovens, the third and sixth ovens being the key ovens having a temperature of 250-260 degrees Celsius, the cord fabric in the third and sixth ovens reaching a tension of 0.3 to 2.9 daN/each yarn of the cord fabric, and running speed of the cord fabric to 55 to 70 m/min, to produce the polyester cord fabric; wherein the polyester cord fabric has yarns having a denier of 500~ 1000D (555,55 to 1111,11 dTex). 1) spinning, reducing melt discharge volume for extruding yarn with denier of 500~1000D (555,55 to 1111,11 dTex) ; using high-speed motor and heat roller, and spinning speed of 6000~6500 m/min to produce raw yarn; wherein the raw yarn has a modulus of 105 to 120 mN/dTex and a strength of 9.0 to 9.5 g/d (9,99 to 10,54 g/dTex); 2) twisting yarn, performing initial and repeat twisting of the raw yarn by a straight twisting machine to produce cords; 3) weaving, performing weaving of the cords by using a Dornier air-jet loom to produce a cord fabric; and when reeding, feeding two cords into each dent of the reed, and at the same time using a creel having a creel roller bearing and creel single spindle tension control belt to control a tension of the cords and thereby improve uniformity of the fabric; 4) dipping, performing dipping of the cord fabric using two-bath dipping method, pretreating the cord fabric in six ovens in a successive manner and then dipping the cord fabric in glue grooves, wherein each oven has a different temperature and a tension zone is provided in five of said ovens, the third and sixth ovens being the key ovens having a temperature of 250-260 degrees Celsius, the cord fabric in the third and sixth ovens reaching a tension of 0.3 to 2.9 daN/each yarn of the cord fabric, and running speed of the cord fabric to 55 to 70 m/min, to produce the polyester cord fabric; wherein the polyester cord fabric has yarns having a denier of 500~ 1000D (555,55 to 1111,11 dTex).
A window material for an ultraviolet light emitting device for emitting an ultraviolet light having a wavelength of 300 nm or less, wherein the window material contains translucent alumina, and a surface of the window material has an average grain diameter of 6 to 60 μm, characterized in that one surface of the window material has a surface roughness Ra of 0.03 μm or less, and another surface of the window material , which faces the one surface , has a surface roughness Ra of 0.2 to 0.6 μm.
An in vitro method of determining homologous recombination (HR) deficiency status in a subject having ovarian cancer, wherein the method comprises (a) determining copy number variation (CNV) of a genomic locus in a DNA test sample of cancer cells from the subject, wherein the genomic locus is selected from a pool of genomic loci comprising or consisting of the loci set forth in Table 1 and/or Table 2; wherein similarity between the CNVs of the pool of genomic loci in the DNA test sample and the CNVs of the pool of genomic loci of a reference sample of BRCA-like mutated cancer cells identifies the subject as HR deficient; and/or similarity between the CNVs in the pool of genomic loci in the DNA of the test sample and the CNVs in the pool of genomic loci of the control sample of BRCA non-mutated cancer cells identifies the subject as not being HR deficient, wherein similarity is the distance measure between centroids of the two classes, i.e ., the control and the reference sample, and the centroid of the test sample, wherein the centroid of a class is constructed by shrinking the class centroid by an optimization routine towards the overall centroid of both classes after standardizing by the within-class standard deviation for each CNV; and optionally (b) transmitting the result to the subject or a third party, preferably a physician or genetic counselor. (a) determining copy number variation (CNV) of a genomic locus in a DNA test sample of cancer cells from the subject, wherein the genomic locus is selected from a pool of genomic loci comprising or consisting of the loci set forth in Table 1 and/or Table 2; wherein similarity between the CNVs of the pool of genomic loci in the DNA test sample and the CNVs of the pool of genomic loci of a reference sample of BRCA-like mutated cancer cells identifies the subject as HR deficient; and/or similarity between the CNVs in the pool of genomic loci in the DNA of the test sample and the CNVs in the pool of genomic loci of the control sample of BRCA non-mutated cancer cells identifies the subject as not being HR deficient, wherein similarity is the distance measure between centroids of the two classes, i.e ., the control and the reference sample, and the centroid of the test sample, wherein the centroid of a class is constructed by shrinking the class centroid by an optimization routine towards the overall centroid of both classes after standardizing by the within-class standard deviation for each CNV; and optionally (b) transmitting the result to the subject or a third party, preferably a physician or genetic counselor.
A breath analyzer , comprising: an input that receives a breath sample; a first sensor that contacts the breath sample, wherein the first sensor comprises polyaniline and a conductive material, wherein the polyaniline contacts the conductive material, wherein the polyaniline is doped with a first dopant that increases pH sensitivity of the polyaniline, and wherein the polyaniline has a resistivity that increases in response to increased concentration of ammonia; a second sensor that contacts the breath sample, wherein the second sensor comprises polypyrrole and a conductive material, wherein the polypyrrole contacts the conductive material, wherein the polypyrrole is doped with a second dopant that increases pH sensitivity of the polypyrrole, and wherein the polypyrrole has a resistivity that increases in response to increased concentration of carbon dioxide; a processor ; and an electrical circuit , wherein the electrical circuit operably connects the first and second sensors to the processor, wherein the processor detects resistivity in the electrical circuit and uses the resistivity to calculate a total concentration of ammonia and a total concentration of carbon dioxide in the breath sample. an input that receives a breath sample; a first sensor that contacts the breath sample, wherein the first sensor comprises polyaniline and a conductive material, wherein the polyaniline contacts the conductive material, wherein the polyaniline is doped with a first dopant that increases pH sensitivity of the polyaniline, and wherein the polyaniline has a resistivity that increases in response to increased concentration of ammonia; a second sensor that contacts the breath sample, wherein the second sensor comprises polypyrrole and a conductive material, wherein the polypyrrole contacts the conductive material, wherein the polypyrrole is doped with a second dopant that increases pH sensitivity of the polypyrrole, and wherein the polypyrrole has a resistivity that increases in response to increased concentration of carbon dioxide; a processor ; and an electrical circuit , wherein the electrical circuit operably connects the first and second sensors to the processor, wherein the processor detects resistivity in the electrical circuit and uses the resistivity to calculate a total concentration of ammonia and a total concentration of carbon dioxide in the breath sample.
A mounting assembly for a hair cutting appliance, the mounting assembly comprising: a head configured to receive a cutting unit; a base , wherein the head is mounted to the base via a pair of arms to form a linkage, each arm being coupled at a joint to a head coupling on the head , and coupled at a joint to a respective base coupling on the base , the base couplings spaced apart along a movement line, and each joint configured to permit pivoting movement about parallel pivot axes; a stroke limiter configured to obstruct pivoting movement of the head relative to the base beyond a limit; characterised in that at least one of the base couplings is a flexible base coupling which is elastically mounted to a body of the base such that the respective flexible base coupling is moveable relative to the body in a direction having a component which is parallel to the movement line and away from the other base coupling , to permit pivoting movement of the head relative to the base beyond the limit imposed by the stroke limiter . a head configured to receive a cutting unit; a base , wherein the head is mounted to the base via a pair of arms to form a linkage, each arm being coupled at a joint to a head coupling on the head , and coupled at a joint to a respective base coupling on the base , the base couplings spaced apart along a movement line, and each joint configured to permit pivoting movement about parallel pivot axes; a stroke limiter configured to obstruct pivoting movement of the head relative to the base beyond a limit; characterised in that at least one of the base couplings is a flexible base coupling which is elastically mounted to a body of the base such that the respective flexible base coupling is moveable relative to the body in a direction having a component which is parallel to the movement line and away from the other base coupling , to permit pivoting movement of the head relative to the base beyond the limit imposed by the stroke limiter .