mhurhangee/patent-ind-claim-en huggingface dataset:
An interlock, having - at least one bolt element which is movable at least between an interlock position and an opening position, wherein the bolt element is received in a receptacle in the interlock position, - wherein a signal circuit connected to a resonant circuit is provided, which outputs an enable signal when the resonant circuit is excited resonantly with an enable frequency, - wherein the resonant circuit has at least one inductive component arranged on the receptacle , and the bolt element has at least one ferromagnetic part, - wherein, in the interlock position, the bolt element having the ferromagnetic part is arranged relative to the inductive component such that a resonance frequency of the resonant circuit corresponds to the enable frequency, - and, in the opening position, the bolt element having the ferromagnetic part is arranged relative to the inductive component such that the resonance frequency of the resonant circuit differs from the enable frequency, characterized in that the inductive component is a coil having at least one winding, wherein the winding is arranged on the receptacle such that the ferromagnetic part is arranged within the winding in the interlock position. - at least one bolt element which is movable at least between an interlock position and an opening position, wherein the bolt element is received in a receptacle in the interlock position, - wherein a signal circuit connected to a resonant circuit is provided, which outputs an enable signal when the resonant circuit is excited resonantly with an enable frequency, - wherein the resonant circuit has at least one inductive component arranged on the receptacle , and the bolt element has at least one ferromagnetic part, - wherein, in the interlock position, the bolt element having the ferromagnetic part is arranged relative to the inductive component such that a resonance frequency of the resonant circuit corresponds to the enable frequency, - and, in the opening position, the bolt element having the ferromagnetic part is arranged relative to the inductive component such that the resonance frequency of the resonant circuit differs from the enable frequency, characterized in that the inductive component is a coil having at least one winding, wherein the winding is arranged on the receptacle such that the ferromagnetic part is arranged within the winding in the interlock position.
A composition for use in killing HIV infected cells within a human infected with HIV, wherein said composition comprises: (a) a Bcl-2 inhibitor, and (b) a latency reversing agent. (a) a Bcl-2 inhibitor, and (b) a latency reversing agent.
A method for sterilizing a substrate having a hydrophilic coating, said method comprising: forming the hydrophilic coating directly on an untreated surface of the substrate; contacting the hydrophilic coating of the substrate with a wetting fluid containing one or more non-polymeric polyols, the hydrophilic coating including a hydrophilic polymer and low molecular weight diacrylate; and sterilizing the medical device by applying a sufficient amount of radiation while the device is in contact with the wetting fluid. forming the hydrophilic coating directly on an untreated surface of the substrate; contacting the hydrophilic coating of the substrate with a wetting fluid containing one or more non-polymeric polyols, the hydrophilic coating including a hydrophilic polymer and low molecular weight diacrylate; and sterilizing the medical device by applying a sufficient amount of radiation while the device is in contact with the wetting fluid.
A connecting structure of a wave guide converter , the connecting structure including a converter and a transmission line , comprising: a first substrate in which a hollow waveguide that propagates a high frequency signal is formed so as to pierce through the first substrate ; and a second substrate that is layered on the first substrate , and in which the converter is arranged at a connecting point with the hollow waveguide and the transmission line extends from the converter and that propagates the high frequency signal, wherein a choke structure to shield a leak of the high frequency signal is arranged around the hollow waveguide on a surface of the first substrate opposing to the second substrate so as to surround the hollow waveguide keeping a predetermined interval from the hollow waveguide , and the first substrate and the second substrate are fixed so as to be non-electrically connected to each other by adhesive that is arranged at a position outside the choke structure between the substrates, the adhesive being arranged so as to surround the choke structure , the adhesive being a non-conductive sheet adhesive having such viscosity that the adhesive does not flow out at the time of application, wherein the adhesive is arranged so as to be sandwiched between the first substrate and the second substrate . a first substrate in which a hollow waveguide that propagates a high frequency signal is formed so as to pierce through the first substrate ; and a second substrate that is layered on the first substrate , and in which the converter is arranged at a connecting point with the hollow waveguide and the transmission line extends from the converter and that propagates the high frequency signal, wherein a choke structure to shield a leak of the high frequency signal is arranged around the hollow waveguide on a surface of the first substrate opposing to the second substrate so as to surround the hollow waveguide keeping a predetermined interval from the hollow waveguide , and the first substrate and the second substrate are fixed so as to be non-electrically connected to each other by adhesive that is arranged at a position outside the choke structure between the substrates, the adhesive being arranged so as to surround the choke structure , the adhesive being a non-conductive sheet adhesive having such viscosity that the adhesive does not flow out at the time of application, wherein the adhesive is arranged so as to be sandwiched between the first substrate and the second substrate .
System for moving transport bodies excited by permanent magnets over an inductively excited magnetic field, comprising induction coils which are designed to be flowed through by a current, in order to levitate the transport bodies contactlessly and drive them in a plane, characterized in that a movably supported first reluctance element and an actuator are provided, wherein the actuator is designed to bring the first reluctance element from a first position into a second position, wherein a permanent magnetic field of a transport body located over the first reluctance element experiences a smaller magnetic resistance in a magnetic circuit as a result of the first reluctance element in the second position than in the first position.
Method for receiving a CPM signal, Continuous Phase Modulation signal, with space-time coding, said signal being a SOQPSK-TG signal, Shaped Offset Quadrature Phase Shift Keying - Telemetry Group based on the IRIG-106 recommendation transmitted from two transmitting antennas noted A1, A2 the received signal modulating a plurality of bits b i j j=0 or 1 and corresponds to the bits transmitted on antenna A1 and A2 respectively, said received signal comprising a time offsetΔτ taking into account the time offset between the signals transmitted from each antenna A1, A2, said signal being received on one or more receiving antennas A3; the method comprises the following steps : - obtaining over an antenna a sampled digital signal y(k) and its offset version y Δτ (k) taking into account the time offset between the two transmitting antennas, each comprising the contributions of the signals output from the two transmitting antennas, said digital signals being expressed according to the following decomposition: s p t ≈ ∑ i ρ 0,2 i p w 0 t − 2 iT b − ρ 1,2 i + 1 p w 1 t − 2 iT b − T b + ∑ i ρ 0,2 i + 1 p w 0 t − 2 iT b − T b − ρ 1,2 i p w 1 t − 2 iT b where : - T b is the duration of one bit ; p ∈ 0,1 - ρ 0 , i 0 , ρ 1 , i 0 are pseudo-symbols corresponding to the information bits b i 0 transmitted over the antenna A1, ρ 0 , i 1 , ρ 1 , i 1 are pseudo-symbols corresponding to the information bits b i 1 transmitted over the antenna A2; - w 0 ( t ) et w 1 ( t ) are shaping pulses, respectively a main pulse and a secondary pulse - defining a Viterbi algorithm (Treillis 1, Treillis 2) having a lattice with a fixed number of states and metrics also depending on at least said main impulse; - obtaining, by means of said Viterbi algorithm, LLRs, Log Likelihood Ratio, on the transmitted information bits. - obtaining over an antenna a sampled digital signal y(k) and its offset version y Δτ (k) taking into account the time offset between the two transmitting antennas, each comprising the contributions of the signals output from the two transmitting antennas, said digital signals being expressed according to the following decomposition: s p t ≈ ∑ i ρ 0,2 i p w 0 t − 2 iT b − ρ 1,2 i + 1 p w 1 t − 2 iT b − T b + ∑ i ρ 0,2 i + 1 p w 0 t − 2 iT b − T b − ρ 1,2 i p w 1 t − 2 iT b where : - T b is the duration of one bit ; p ∈ 0,1 - ρ 0 , i 0 , ρ 1 , i 0 are pseudo-symbols corresponding to the information bits b i 0 transmitted over the antenna A1, ρ 0 , i 1 , ρ 1 , i 1 are pseudo-symbols corresponding to the information bits b i 1 transmitted over the antenna A2; - w 0 ( t ) et w 1 ( t ) are shaping pulses, respectively a main pulse and a secondary pulse - defining a Viterbi algorithm (Treillis 1, Treillis 2) having a lattice with a fixed number of states and metrics also depending on at least said main impulse; - obtaining, by means of said Viterbi algorithm, LLRs, Log Likelihood Ratio, on the transmitted information bits.
A device for controlling movement of a first member relative to a second member , said device comprising damping means actuable by movement of said first member in a first direction (B) to impart a damped resistive force to the first member in opposition to its movement in said first direction, said device further comprising gearing means for converting movement of the first member in said first direction into two or more different rates of actuation of the damping means over at least part of the travel of the first member, with said gearing means including a first pinion and first and second racks , with the first pinion being engageable with one of the first and second racks, with the first rack being mounted in a fixed position relative to the second member and the first pinion being movable relative thereto, with the gearing means being operable to produce a lesser rate of actuation of the damping means over an initial portion of travel of the first member and a greater rate of actuation of the damping means over a subsequent portion of the first member's travel, wherein that the gearing means further includes a second pinion , characterised in that the first pinion is in engagement with both of the first and second racks , in that the second rack is movable relative to the second member , and in that the second pinion is engagable by one of the first and second racks and by a third rack .
A simulation system , comprising: a simulator configured to execute a simulation of an operation of a PLC and an operation of one or more factory automation devices controlled by the PLC ; a data input unit configured to obtain in the simulation one or more execution times of a program installed in the PLC , positional information of each one of one or more objects in a 3D space in the simulation, and a value of each one of one or more variables referred to by the program to operate the one or more factory automation devices; a data recorder configured to store, as a first log, the positional information of the one or more objects and the value of the one or more variables for each of the one or more execution times in a manner that the positional information and the value are associated with each other; and a displayer configured to display the 3D space including the one or more objects reproduced based on the positional information, display the positional information of the one or more objects and display the value of the one or more variables for each of the one or more execution times included in the first log . a simulator configured to execute a simulation of an operation of a PLC and an operation of one or more factory automation devices controlled by the PLC ; a data input unit configured to obtain in the simulation one or more execution times of a program installed in the PLC , positional information of each one of one or more objects in a 3D space in the simulation, and a value of each one of one or more variables referred to by the program to operate the one or more factory automation devices; a data recorder configured to store, as a first log, the positional information of the one or more objects and the value of the one or more variables for each of the one or more execution times in a manner that the positional information and the value are associated with each other; and a displayer configured to display the 3D space including the one or more objects reproduced based on the positional information, display the positional information of the one or more objects and display the value of the one or more variables for each of the one or more execution times included in the first log .
A compound of Formula : or a pharmaceutically acceptable salt of the compound, wherein: a) T is -C(=O)-; R1 and R2 are each independently an aryl group, substituted with one or more substituents selected from the group consisting of -C 1 -C 6 alkyl, halo, CN, -COOH, -OH, -C 1 -C 6 alkoxy, - NH 2 , -(C 1 -C 6 alkyl)NH 2 , -(C 1 -C 6 alkyl)NH(C 1 -C 6 alkyl), -(C 1 -C 6 alkyl)N(C 1 -C 6 alkyl) 2 , - NH(C 1 -C 6 alkyl), -N(C 1 -C 6 alkyl) 2 , -CONH 2 , -NH(CO)(C 1 -C 6 alkyl) and -N(C 1 -C 6 alkyl)CO(C 1 -C 6 alkyl); and R3 is hydrogen; or b) T is -C(=O)-; R1 is a 4-bromophenyl group, R2 is a phenyl group and R3 is hydrogen, having the structure (Compound 29). a) T is -C(=O)-; R1 and R2 are each independently an aryl group, substituted with one or more substituents selected from the group consisting of -C 1 -C 6 alkyl, halo, CN, -COOH, -OH, -C 1 -C 6 alkoxy, - NH 2 , -(C 1 -C 6 alkyl)NH 2 , -(C 1 -C 6 alkyl)NH(C 1 -C 6 alkyl), -(C 1 -C 6 alkyl)N(C 1 -C 6 alkyl) 2 , - NH(C 1 -C 6 alkyl), -N(C 1 -C 6 alkyl) 2 , -CONH 2 , -NH(CO)(C 1 -C 6 alkyl) and -N(C 1 -C 6 alkyl)CO(C 1 -C 6 alkyl); and R3 is hydrogen; or R1 and R2 are each independently an aryl group, substituted with one or more substituents selected from the group consisting of -C 1 -C 6 alkyl, halo, CN, -COOH, -OH, -C 1 -C 6 alkoxy, - NH 2 , -(C 1 -C 6 alkyl)NH 2 , -(C 1 -C 6 alkyl)NH(C 1 -C 6 alkyl), -(C 1 -C 6 alkyl)N(C 1 -C 6 alkyl) 2 , - NH(C 1 -C 6 alkyl), -N(C 1 -C 6 alkyl) 2 , -CONH 2 , -NH(CO)(C 1 -C 6 alkyl) and -N(C 1 -C 6 alkyl)CO(C 1 -C 6 alkyl); and R3 is hydrogen; or b) T is -C(=O)-; R1 is a 4-bromophenyl group, R2 is a phenyl group and R3 is hydrogen, having the structure (Compound 29).
A method of testing whether a patient suffering from multiple myeloma will respond or not to a combination treatment consisting of at least one hydroxamate histone deacetylase inhibitor (hydroxamate HDACi) with at least one DNA methyltransferase inhibitor (DNMTi) comprising: i) determining the expression level (ELi) of genes G 1 -G 96 of table A in a biological sample obtained from said patient ii) comparing for each gene the expression level (ELi) determined at step i) with a corresponding predetermined reference level (ELRi) indicated in Table A iii) calculating the HADMS score trough the following formula HADMS = ∑ i = 1 n βi × Ci wherein βi represent the corresponding regression β coefficient reference value for the gene G i indicated in Table A and Ci = 1 if the expression of the gene G i (ELi) is higher than the predetermined reference level (ELRi) or Ci = -1 if the expression of the gene (ELi) is lower than or equal to the predetermined reference level (ELRi) iv) comparing the score HADMS determined at step iii) with a predetermined reference value HADMS R wherein said HADMS R is equal to -21.57 v) and concluding that the patient will respond to the combination treatment when the HADMS score is higher than the predetermined reference value HADMS R or concluding that the patient will not respond to the combination treatment when the HADMS score is lower than the predetermined reference value HADMS R . i) determining the expression level (ELi) of genes G 1 -G 96 of table A in a biological sample obtained from said patient ii) comparing for each gene the expression level (ELi) determined at step i) with a corresponding predetermined reference level (ELRi) indicated in Table A iii) calculating the HADMS score trough the following formula HADMS = ∑ i = 1 n βi × Ci wherein βi represent the corresponding regression β coefficient reference value for the gene G i indicated in Table A and Ci = 1 if the expression of the gene G i (ELi) is higher than the predetermined reference level (ELRi) or Ci = -1 if the expression of the gene (ELi) is lower than or equal to the predetermined reference level (ELRi) iv) comparing the score HADMS determined at step iii) with a predetermined reference value HADMS R wherein said HADMS R is equal to -21.57 v) and concluding that the patient will respond to the combination treatment when the HADMS score is higher than the predetermined reference value HADMS R or concluding that the patient will not respond to the combination treatment when the HADMS score is lower than the predetermined reference value HADMS R .
A system for closing a puncture, the system comprising: a sealant ; a sealant sleeve extending along a longitudinal axis of the system and moveable relative to the sealant in a direction parallel to the longitudinal axis, wherein the sealant is disposed in the sealant sleeve; a pull rack coupled to a proximal section of the sealant sleeve and slidably positioned in an outer housing ; a support member disposed in the sealant sleeve proximal to the sealant; a push rack coupled to a proximal section of the support member and slidably positioned in the outer housing ; and a push rack lock comprising an arm and a push rack engagement portion at an end of the arm, the push rack lock having a locked position in which the push rack engagement portion contacts the push rack to prevent distal movement of the push rack and an unlocked position in which the push rack engagement portion is spaced from the push rack in a direction lying in a plane perpendicular to the longitudinal axis to allow distal movement of the push rack; wherein the device comprises a deployment actuator actuatable to move the pull rack and sealant sleeve proximally and move the push rack distally, and the push rack lock is moveable from the locked position to the unlocked position upon proximal movement of the pull rack. a sealant ; a sealant sleeve extending along a longitudinal axis of the system and moveable relative to the sealant in a direction parallel to the longitudinal axis, wherein the sealant is disposed in the sealant sleeve; a pull rack coupled to a proximal section of the sealant sleeve and slidably positioned in an outer housing ; a support member disposed in the sealant sleeve proximal to the sealant; a push rack coupled to a proximal section of the support member and slidably positioned in the outer housing ; and a push rack lock comprising an arm and a push rack engagement portion at an end of the arm, the push rack lock having a locked position in which the push rack engagement portion contacts the push rack to prevent distal movement of the push rack and an unlocked position in which the push rack engagement portion is spaced from the push rack in a direction lying in a plane perpendicular to the longitudinal axis to allow distal movement of the push rack; wherein the device comprises a deployment actuator actuatable to move the pull rack and sealant sleeve proximally and move the push rack distally, and the push rack lock is moveable from the locked position to the unlocked position upon proximal movement of the pull rack.
An immunity enhancing agent for use in the suppression of progress of, suppression of recurrence of, and/or treatment of cancer, comprising an Allergin-1 antagonist as an active ingredient, wherein the Allergin-1 antagonist is an anti-Allergin-1 antibody, an Allergin-1 binding protein, or an Allergin-1-fusion protein.
An optical fiber grating demodulator, comprising: a working chamber for housing an optical device (102, 103, 104, 112; 212, 219, 220), comprising a hole on a sidewall, through which the optical device (102, 103, 104, 112; 212, 219, 220) is connectable by an optical fiber to an optical fiber grating sensor external to the optical fiber grating demodulator; a heat insulation layer enclosing the working chamber for insulating the optical device (102, 103, 104, 112; 212, 219, 220) from an external of the working chamber with respect to heat exchange; and a temperature control system (101, 113, 114; 201, 214, 217, 218) coupled to the working chamber to adjust a temperature within the working chamber such that the temperature within the working chamber meets a temperature threshold (T). a working chamber for housing an optical device (102, 103, 104, 112; 212, 219, 220), comprising a hole on a sidewall, through which the optical device (102, 103, 104, 112; 212, 219, 220) is connectable by an optical fiber to an optical fiber grating sensor external to the optical fiber grating demodulator; a heat insulation layer enclosing the working chamber for insulating the optical device (102, 103, 104, 112; 212, 219, 220) from an external of the working chamber with respect to heat exchange; and a temperature control system (101, 113, 114; 201, 214, 217, 218) coupled to the working chamber to adjust a temperature within the working chamber such that the temperature within the working chamber meets a temperature threshold (T).