mhurhangee/patent-ind-claim-en huggingface dataset:
A method for cloning a full length coding sequence for a light chain of a rabbit monoclonal antibody having a b4 allotype, the method comprising the steps of: a) providing a rabbit antibody-producing B-lymphocyte having a b4 allotype; b) fusing the B-lymphocyte of step a) with a rabbit fusion partner cell having a b5 allotype to produce a hybridoma cell capable of producing an antibody; c) isolating cDNA from the hybridoma; d) amplifying the b4 light chain domain from the cDNA of step c) using: a light chain primer pair that spans the start and stop codons of the light chain cDNA and is able to amplify the full length light chain polynucleotide, wherein said primer pair comprises (i) a forward primer having at the 3' end a sequence according to SEQ ID NO: 1 or SEQ ID NO: 6 and (ii) a reverse primer having at the 3' end a sequence of SEQ ID NO: 5, wherein the 3' end has at least 15 nucleotides of complementarity with the light chain cDNA of SEQ ID NO: 14; e) cloning the amplified light chain domain obtained in step d) into a plasmid for expression. a) providing a rabbit antibody-producing B-lymphocyte having a b4 allotype; b) fusing the B-lymphocyte of step a) with a rabbit fusion partner cell having a b5 allotype to produce a hybridoma cell capable of producing an antibody; c) isolating cDNA from the hybridoma; d) amplifying the b4 light chain domain from the cDNA of step c) using: a light chain primer pair that spans the start and stop codons of the light chain cDNA and is able to amplify the full length light chain polynucleotide, wherein said primer pair comprises (i) a forward primer having at the 3' end a sequence according to SEQ ID NO: 1 or SEQ ID NO: 6 and (ii) a reverse primer having at the 3' end a sequence of SEQ ID NO: 5, wherein the 3' end has at least 15 nucleotides of complementarity with the light chain cDNA of SEQ ID NO: 14; (i) a forward primer having at the 3' end a sequence according to SEQ ID NO: 1 or SEQ ID NO: 6 and (ii) a reverse primer having at the 3' end a sequence of SEQ ID NO: 5, wherein the 3' end has at least 15 nucleotides of complementarity with the light chain cDNA of SEQ ID NO: 14; e) cloning the amplified light chain domain obtained in step d) into a plasmid for expression.
Panel of flaps for an air intake of motor vehicle comprising a plurality of flaps mounted with the ability to pivot about a respective longitudinal pivot axis (A), the longitudinal pivot axes (A) extending parallel to one another and being disposed side by side, the aligned longitudinal pivot axes (A) lying within a curved surface (S), characterized in that it comprises at least one flexible drive shaft connected to the flaps extending perpendicularly to the longitudinal pivot axes (A) of the flaps .
An isolated form of isomyosmine or a pharmaceutically acceptable salt thereof for use in the treatment of hair loss associated with androgenetic alopecia; anagen effluvium; telogen effluvium; alopecia greata; scarring alopecia; loose anagen syndrome; tinia capitis; ichthyosiform erythroderma; menopause; postpartum; autoimmune disorders; infection; allergic reaction; anorexia; or traction alopecia.
A method for producing plastic straps , comprising providing a semi-crystalline thermoplastic plastic material , melting the plastic material , extruding the melted plastic material into at least one plastic strand by means of an extrusion apparatus , cooling the extruded plastic strand , monoaxially or predominantly monoaxially stretching the plastic strand into an stretched strand by means of at least one stretching device , said stretched strand comprising two surfaces spaced from one another by a thickness of the stretched strand , wherein at least one surface of the stretched strand is provided with an embossing by means of an embossing device comprising at least one embossing roller , said embossing roller comprising on its roller surface projections for generating recesses on the at least one surface of the stretched strand, wherein as the at least one embossing roller , an embossing roller is used, the projections of which comprise flat or predominantly flat plateau surfaces for generating flat or predominantly flat base surfaces of the recesses on the at least one surface of the stretched strand , characterized in that the plateau surfaces of the projections are dimensioned such and that the projections are arranged on the roller surface spaced from one another such, that between 44 % and 55 % of a respective entire parallel projection, viewed from a vertical top view, of the respective at least one embossed strap surface of the plastic straps is formed by the total amount of the base surfaces of the recesses .
A compressor structure comprising: a diffuser vane, comprising a vane body , wherein a cavity is formed inside the vane body , gas supplement holes are formed on the vane body , and the compressor structure further comprises: a housing, on which a gas supplement passage in communication with the cavity of the diffuser vane is formed, characterized in that the gas supplement holes are all disposed on a suction surface of the vane body such that the gas supplement holes are configured to form a jet flow on the suction surface to blow off a low-speed and low-energy area formed on the suction surface.
A dynamically balancing vehicle - comprising a chassis , which has a lower frame and an upper frame , which is fixedly connected to said lower frame and which is arranged above the lower frame in relation to a vehicle vertical axis (Z), - comprising a vehicle seat , which is supported by the upper frame , for a vehicle driver, - comprising at least two wheels for supporting the lower frame on an underlying surface , which wheels are mounted on the lower frame so as to be rotatable about a common wheel axis of rotation , which runs parallel to a vehicle transverse axis (Y), - comprising a drive device , which is coupled to the wheels , for dynamically balancing the vehicle and for driving, braking and steering the vehicle , - comprising a steering device for generating steering commands, which has a steering rod , which can be operated by the vehicle driver and which, by way of a steering mount , is mounted so as to be pivotable about a steering axis , which runs parallel to a vehicle longitudinal axis (X), characterized in - that the steering rod is, by way of the steering mount , mounted on the lower frame so as to be pivotable about the steering axis , - that a coupling device is provided, which connects the upper frame to the steering rod for transmission of tensile and compressive forces in the vehicle longitudinal axis (X) and which permits relative movements between the steering rod and the upper frame in the vehicle transverse axis (Y). - comprising a chassis , which has a lower frame and an upper frame , which is fixedly connected to said lower frame and which is arranged above the lower frame in relation to a vehicle vertical axis (Z), - comprising a vehicle seat , which is supported by the upper frame , for a vehicle driver, - comprising at least two wheels for supporting the lower frame on an underlying surface , which wheels are mounted on the lower frame so as to be rotatable about a common wheel axis of rotation , which runs parallel to a vehicle transverse axis (Y), - comprising a drive device , which is coupled to the wheels , for dynamically balancing the vehicle and for driving, braking and steering the vehicle , - comprising a steering device for generating steering commands, which has a steering rod , which can be operated by the vehicle driver and which, by way of a steering mount , is mounted so as to be pivotable about a steering axis , which runs parallel to a vehicle longitudinal axis (X), - that the steering rod is, by way of the steering mount , mounted on the lower frame so as to be pivotable about the steering axis , - that a coupling device is provided, which connects the upper frame to the steering rod for transmission of tensile and compressive forces in the vehicle longitudinal axis (X) and which permits relative movements between the steering rod and the upper frame in the vehicle transverse axis (Y).
A heating system for heating of a feed gas, said heating system comprising: - a supply of feed gas ; - a structured body arranged for heating of said feed gas, said structured body comprising a macroscopic structure of electrically conductive material; - a pressure shell housing said structured body, said pressure shell comprising an inlet for letting in said feed gas and an outlet for letting out heated gas, wherein said inlet is positioned so that said feed gas enters said structured body in a first end of said structured body and said heated gas exits said structured body from a second end of said structured body; - a heat insulation layer between said structured body and said pressure shell; - at least two conductors electrically connected to said structured body and to an electrical power supply placed outside said pressure shell, wherein said electrical power supply is dimensioned to heat at least part of said structured body to a temperature of at least 400°C by passing an electrical current through said macroscopic structure, wherein said at least two conductors are connected to the structured body at a position on the structured body closer to said first end of said structured body than to said second end of said structured body, and wherein the structured body is constructed to direct an electrical current to run from one conductor substantially to the second end of the structured body and return to a second of said at least two conductors; and, - an outlet for heated gas. - a supply of feed gas ; - a structured body arranged for heating of said feed gas, said structured body comprising a macroscopic structure of electrically conductive material; - a pressure shell housing said structured body, said pressure shell comprising an inlet for letting in said feed gas and an outlet for letting out heated gas, wherein said inlet is positioned so that said feed gas enters said structured body in a first end of said structured body and said heated gas exits said structured body from a second end of said structured body; - a heat insulation layer between said structured body and said pressure shell; - at least two conductors electrically connected to said structured body and to an electrical power supply placed outside said pressure shell, wherein said electrical power supply is dimensioned to heat at least part of said structured body to a temperature of at least 400°C by passing an electrical current through said macroscopic structure, wherein said at least two conductors are connected to the structured body at a position on the structured body closer to said first end of said structured body than to said second end of said structured body, and wherein the structured body is constructed to direct an electrical current to run from one conductor substantially to the second end of the structured body and return to a second of said at least two conductors; and, - an outlet for heated gas.
The method of disposal of radioactive waste, containing cobalt, neodymium, strontium or cesium, to be approved by, permanently embeded it into silica glass, characterized in that , cobalt neodymium, strontium or cesium nitrates solution in ethanol, is added to tetraethoxysilane (TEOS), a bright blend thereof in the case of cobalt and neodymium nitrates, dilute in ethanol, and then ascorbic acid solution, dropwise in case of cesium or strontium nitrates, after which the mixture is mixed at room temperature for 2 to 5 hours, favorably for 4 hours, leading a preliminary hydrolysis, then obtained silica-hydroxy-nitrate-ascorbic acid sol with cobalt, neodymium, strontium or cesium, undergo further hydrolysis, in the second stage of hydrolysis and polymerization, at a temperature of 40°C - 80°C, favorably 70°C and then it is evaporated to dryness under reduced pressure 0.1 MPa, and obtained gel is subjected to a heat treatment in a 1200°C, favorably by approximately 4 hours from the heating rate of 2 °C/min to the receipt of the final product silica glass with cobalt, neodymium, strontium or cesium permanently built into its structure.
A method for enabling visualization of an indication of a radius of a spherically shaped surface portion of a tip of an instrument relative to image data of an object in a virtual space , wherein the spherically shaped surface portion has a centre point , wherein a calibration device is provided that comprises a calibration structure defining an opening angle and that is configured to cooperate with the spherically shaped surface portion so as to guide a tilting movement of the instrument tip around the centre point , wherein the calibration device comprises a first tracker trackable by a tracking system and arranged in a predetermined relationship relative to the calibration structure , and wherein the instrument comprises a second tracker trackable by the tracking system and the object comprises a third tracker trackable by the tracking system , the method being performed by a computer system and comprising: determining a first pose of the first tracker ; determining positional data of the second tracker for different tilting positions of the instrument while the spherically shaped surface portion is in abutment with the calibration structure ; determining a position of the centre point relative to the second tracker based on the positional data and determining the radius of the spherically shaped surface portion based on the first pose, the positional data, the predetermined relationship, and the opening angle ; tracking the third tracker to track a second pose of the image data of the object in the virtual space ; tracking the second tracker to track a position of the centre point in the virtual space based on the position of the centre point relative to the second tracker ; and generating first display instructions for displaying in the virtual space , based on the second pose of the image data of the object in the virtual space , the position of the centre point in the virtual space and the radius , a visual representation indicative of the radius relative to the image data of the object . determining a first pose of the first tracker ; determining positional data of the second tracker for different tilting positions of the instrument while the spherically shaped surface portion is in abutment with the calibration structure ; determining a position of the centre point relative to the second tracker based on the positional data and determining the radius of the spherically shaped surface portion based on the first pose, the positional data, the predetermined relationship, and the opening angle ; tracking the third tracker to track a second pose of the image data of the object in the virtual space ; tracking the second tracker to track a position of the centre point in the virtual space based on the position of the centre point relative to the second tracker ; and generating first display instructions for displaying in the virtual space , based on the second pose of the image data of the object in the virtual space , the position of the centre point in the virtual space and the radius , a visual representation indicative of the radius relative to the image data of the object .
Device for operating a generator, which provides a power supply to a towed unit, such as a trailer or a semi-trailer, which has a half-axle which is provided with a running wheel and is connected to the vehicle frame via a pivot lever and a bracket arranged on the bottom of a vehicle frame , the pivot lever being pivotable around a pivot axle at the end facing the bracket and being provided with a pulley which is rotatable around the pivot axle and is driven by the running wheel via a first belt , the running wheel being arranged in a central region in relation to a longitudinal axis of the vehicle frame and at or near a slip-free position of the towed unit, characterized in that the pulley drives a generator via a second belt , which generator is fastened to the vehicle frame and is intended to deliver electrical energy for supply.
Method for adjusting brake pressures of a motor vehicle , wherein a control unit , while taking into account determined dynamic state variables of the wheels that are to be braked, actuates a pressure control valve with an inlet valve for ventilating and with an outlet valve for venting the brake pressure line that is respectively controlled by the pressure control valve , wherein the control times (tA) of the outlet valve are determined depending on the control of the inlet valve , characterized in that on receiving an external braking demand that is independent of the driver's braking demand, in an external braking mode provided for this case, the control unit adjusts the brake pressure in the brake pressure line corresponding to the external braking demand by determining the control times (tA) of the outlet valve depending on the control of the inlet valve .
Pipe connection with at least two pipes with pipe walls of a, in particular the same, plastic monomaterial, wherein an end section of a pipe wall of one of the tubes is connected with an end section of a pipe wall of the other pipe through fusion, wherein the end sections , viewed in a radial direction, are directly fused together in an inner connecting region and in an outer connecting region of the pipe connection , wherein the inner connecting region and the outer connecting region , viewed in a longitudinal section through the pipe connection , are oriented at an angle to one another, characterised in that the pipe connection has at least one material reception space for receiving surplus molten plastic driven out of the inner connecting region and/or the outer connecting region , wherein the material reception space is limited by an annular groove formed in at least one of the end sections.
Method for the production of ethylene and acetic acid, wherein a reaction charge stream containing ethane and oxygen is formed, and a portion of the ethane and the oxygen in the reaction charge stream is converted into ethylene and acetic acid via oxidative dehydrogenation to obtain a process gas, wherein the process gas contains the unconverted portion of the ethane and the oxygen, the ethylene, and the acetic acid as well as water, characterized in that the method includes setting a water partial pressure to a value in a range of between 0.5 and 5 bar (abs.), in particular between 0.7 and 3 bar (abs.), in the process gas as a function of a predetermined product ratio of the acetic acid to the ethylene, wherein one or more reactors are used for the oxidative dehydrogenation, and the water partial pressure is set in this range at a reactor outlet of the reactor or reactors.
A modular patch panel assembly , comprising: a. a first patch panel element including: i. a first surface defining a top or bottom surface of the first patch panel element , and two opposing sidewalls including an interior surface and an exterior surface, and ii. at least one opening configured to receive at least one connector ; b. a first base including: i. a second surface defining a top surface or a bottom surface of the first base , and two opposing sidewalls including an interior surface and an exterior surface, and ii. a protuberance extending outwardly from each of the sidewalls and including an engagement feature , wherein the assembly is characterized in that the first patch panel element is releasably engaged with the engagement features of the protuberances to form a first modular patch panel assembly ; and in that in the releasably engaged configuration, the first surface of the first patch panel element defines a top or bottom exposed surface of the first modular patch panel assembly , and the second surface of the first base defines an opposing top or bottom exposed surface of the first modular patch panel assembly . a. a first patch panel element including: i. a first surface defining a top or bottom surface of the first patch panel element , and two opposing sidewalls including an interior surface and an exterior surface, and ii. at least one opening configured to receive at least one connector ; i. a first surface defining a top or bottom surface of the first patch panel element , and two opposing sidewalls including an interior surface and an exterior surface, and ii. at least one opening configured to receive at least one connector ; b. a first base including: i. a second surface defining a top surface or a bottom surface of the first base , and two opposing sidewalls including an interior surface and an exterior surface, and ii. a protuberance extending outwardly from each of the sidewalls and including an engagement feature , i. a second surface defining a top surface or a bottom surface of the first base , and two opposing sidewalls including an interior surface and an exterior surface, and ii. a protuberance extending outwardly from each of the sidewalls and including an engagement feature ,
Disc brake with an electromechanical actuator for vehicles, in particular for utility vehicles for application to a brake disc via a rotary lever and two brake pads , and the electromechanical actuator comprising an actuator housing , a cam disc which is arranged in the actuator housing via a shaft , and a plunger which is operatively connected to the cam disc along an axial axis (A), characterized in that the cam disc has a stop , and the stop is configured to fix the plunger in a starting position (S) of the rotary lever in the direction of an axial axis (A) of the electromechanical actuator , in an opposed manner with respect to the cam disc .