mhurhangee/patent-ind-claim-en huggingface dataset:
A compound of formula A-I: or a stereoisomer or mixture of stereoisomers, tautomer, pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, isotopologue or polymorph thereof, wherein: R is H, optionally substituted alkyl, or optionally substituted cycloalkyl; R 1 is optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocyclyl; R 2 and R 3 are each halo; where the substituents on R 1 , when present are one to three groups Q, where each Q is independently alkyl, halo, haloalkyl, hydroxyl, alkoxy, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aryl, -R 4 OR 5 , -R 4 SR 5 , - R 4 N(R 6 )(R 7 ), R 4 OR 4 N(R 6 )(R 7 ) or R 4 OR 4 C(J)N(R 6 )(R 7 ); J is O or S; each R 4 is independently alkylene, alkenylene or a direct bond; each R 5 is independently hydrogen, alkyl, haloalkyl or hydroxyalkyl; and R 6 and R 7 are each independently hydrogen or alkyl or R 6 and R 7 together with the nitrogen atom on which they are substituted form a 5 or 6-membered heterocyclyl or heteroaryl ring, optionally substituted with one or two halo, alkyl or haloalkyl. R is H, optionally substituted alkyl, or optionally substituted cycloalkyl; R 1 is optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or optionally substituted heterocyclyl; R 2 and R 3 are each halo; where the substituents on R 1 , when present are one to three groups Q, where each Q is independently alkyl, halo, haloalkyl, hydroxyl, alkoxy, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aryl, -R 4 OR 5 , -R 4 SR 5 , - R 4 N(R 6 )(R 7 ), R 4 OR 4 N(R 6 )(R 7 ) or R 4 OR 4 C(J)N(R 6 )(R 7 ); J is O or S; each R 4 is independently alkylene, alkenylene or a direct bond; each R 5 is independently hydrogen, alkyl, haloalkyl or hydroxyalkyl; and R 6 and R 7 are each independently hydrogen or alkyl or R 6 and R 7 together with the nitrogen atom on which they are substituted form a 5 or 6-membered heterocyclyl or heteroaryl ring, optionally substituted with one or two halo, alkyl or haloalkyl.
A coring tool , comprising: a core tube assembly ; a carrier chamber defined within the core tube assembly for storing one or more core samples drilled from a downhole formation having a wellbore, the wellbore having a wellbore fluid therein, wherein the wellbore fluid has a wellbore fluid density; a non-hydrocarbon, non-reactive heavy weight fluid present within the carrier chamber, the heavy weight fluid exhibiting a heavy weight fluid density of about 2 pounds per gallon (240 kg/m 3 ) greater than the wellbore fluid density; a pressure housing cover selectively rotatable between an open position, where the one or more core samples are able to be inserted into the carrier chamber , and a closed position, where the carrier chamber is sealed; and a cover activation mechanism coupled to the core tube assembly and operable to move the pressure housing cover between the closed position and the open position. a core tube assembly ; a carrier chamber defined within the core tube assembly for storing one or more core samples drilled from a downhole formation having a wellbore, the wellbore having a wellbore fluid therein, wherein the wellbore fluid has a wellbore fluid density; a non-hydrocarbon, non-reactive heavy weight fluid present within the carrier chamber, the heavy weight fluid exhibiting a heavy weight fluid density of about 2 pounds per gallon (240 kg/m 3 ) greater than the wellbore fluid density; a pressure housing cover selectively rotatable between an open position, where the one or more core samples are able to be inserted into the carrier chamber , and a closed position, where the carrier chamber is sealed; and a cover activation mechanism coupled to the core tube assembly and operable to move the pressure housing cover between the closed position and the open position.
A device for piecing a thread at a workstation of a textile machine , comprising a suction nozzle for picking up a thread end of the thread from a bobbin , wherein the suction nozzle includes an extraction mouth , a suction channel as well as an entry opening for the thread , and comprising a feeder unit for forming a thread loop from the thread end picked up by the suction nozzle situated so as to be movable with respect to the suction nozzle , wherein the feeder unit comprises a cover element for closing the entry opening of the suction nozzle , as well as a thread-guiding element , and wherein the feeder unit can be moved back and forth between a first position (I), in which the cover element closes the entry opening of the suction nozzle , and a second position (II), in which the cover element unblocks the entry opening of the suction nozzle , wherein the thread guiding element is situated inside the suction channel in the first position and outside the suction channel in the second position characterized in that the thread-guiding element has an open contour.
An authentication method arranged to provide an encoded or decoded version of an identifier, comprising: generating at least one operable keypad and at least one keypad image, wherein biometric data relating to a user is used to specify a configuration of keys in at least one of the at least one operable keypad and the at least one keypad image; generating a mapping between keys of the at least one operable keypad and keys depicted in the at least one keypad image; and encoding or decoding the identifier using the mapping between the at least one operable keypad and the at least one keypad image. generating at least one operable keypad and at least one keypad image, wherein biometric data relating to a user is used to specify a configuration of keys in at least one of the at least one operable keypad and the at least one keypad image; generating a mapping between keys of the at least one operable keypad and keys depicted in the at least one keypad image; and encoding or decoding the identifier using the mapping between the at least one operable keypad and the at least one keypad image.
A servo amplifier device that incorporates a control drive circuit configured to control and drive a motor , the servo amplifier device comprising: a housing that houses the control drive circuit; an attachment portion for attaching the housing to an installation member; a DC power supply connection unit connected with a DC power supply line to be supplied with DC power; a communication connector connected with an external controller to be supplied with a communication signal; a motor driving connector connected with a drive line for driving the motor ; and a display unit disposed with a display member, wherein the housing has a box shape having a pair of first surfaces facing each other and each having a largest area, the communication connector and the motor driving connector are disposed on a pair of second surfaces perpendicular to the first surfaces and facing each other, on a pair of third surfaces perpendicular to the first surfaces and the second surfaces and facing each other, the attachment portion is disposed on a back surface side with one of the third surfaces being as a back surface , and the display unit and the DC power supply connection unit are disposed on a front surface with another one of the third surfaces being as the front surface . a housing that houses the control drive circuit; an attachment portion for attaching the housing to an installation member; a DC power supply connection unit connected with a DC power supply line to be supplied with DC power; a communication connector connected with an external controller to be supplied with a communication signal; a motor driving connector connected with a drive line for driving the motor ; and a display unit disposed with a display member, wherein the housing has a box shape having a pair of first surfaces facing each other and each having a largest area, the communication connector and the motor driving connector are disposed on a pair of second surfaces perpendicular to the first surfaces and facing each other, on a pair of third surfaces perpendicular to the first surfaces and the second surfaces and facing each other, the attachment portion is disposed on a back surface side with one of the third surfaces being as a back surface , and the display unit and the DC power supply connection unit are disposed on a front surface with another one of the third surfaces being as the front surface .
A controller for a microscope , the controller configured to: receive image data representing tissue ; identify a wound using the image data; wherein identifying the wound is based on at least two images of the tissue with different spectral content; determine the presence of hemoglobin based on the at least two images and identify the wound based on an area where hemoglobin is present or determine the oxygen saturation of the hemoglobin and identify the wound based on the oxygen saturation; and output a control signal for the microscope , the control signal instructing the microscope to adjust its field of view to the wound . receive image data representing tissue ; identify a wound using the image data; wherein identifying the wound is based on at least two images of the tissue with different spectral content; determine the presence of hemoglobin based on the at least two images and identify the wound based on an area where hemoglobin is present or determine the oxygen saturation of the hemoglobin and identify the wound based on the oxygen saturation; and output a control signal for the microscope , the control signal instructing the microscope to adjust its field of view to the wound .
A training device for simulating intranasal drug delivery, the device comprising: an outer sleeve having upper and lower portions; a locking sleeve coupled to the outer sleeve and partially extending therethrough; a core sleeve coupled to the locking sleeve and configured to axially slide within the outer and locking sleeves, the core sleeve having first and second sets of locking features; and a plunger operatively coupled to the core sleeve, the plunger being configured to selectively translate the core sleeve from an initial position to a first actuated position that indicates the release of a first simulated dose of a drug, and the plunger being configured to translate the core sleeve from the first actuated position to a second actuated position that indicates the release of a second simulated dose of the drug; wherein the device does not contain a drug. an outer sleeve having upper and lower portions; a locking sleeve coupled to the outer sleeve and partially extending therethrough; a core sleeve coupled to the locking sleeve and configured to axially slide within the outer and locking sleeves, the core sleeve having first and second sets of locking features; and a plunger operatively coupled to the core sleeve, the plunger being configured to selectively translate the core sleeve from an initial position to a first actuated position that indicates the release of a first simulated dose of a drug, and the plunger being configured to translate the core sleeve from the first actuated position to a second actuated position that indicates the release of a second simulated dose of the drug; wherein the device does not contain a drug.
An audio system (AS) for an ear mountable playback device (HP) comprising - a speaker (SP); - an error microphone (FB_MIC) configured to sense sound being output from the speaker (SP) and ambient sound; the audio system characterized in that it further comprises - a detection engine (DET) configured to - measure a property of a first signal that is applied to the speaker (SP); - measure a property of a second signal that is detected by the error microphone (FB_MIC); - determine a driver response between the speaker (SP) and the error microphone (FE_MIC) by calculating the driver response from the properties of the first and the second signal; and - estimate a leakage condition by comparing the determined driver response to known driver responses at different leakage conditions. - a speaker (SP); - an error microphone (FB_MIC) configured to sense sound being output from the speaker (SP) and ambient sound; - a detection engine (DET) configured to - measure a property of a first signal that is applied to the speaker (SP); - measure a property of a second signal that is detected by the error microphone (FB_MIC); - determine a driver response between the speaker (SP) and the error microphone (FE_MIC) by calculating the driver response from the properties of the first and the second signal; and - estimate a leakage condition by comparing the determined driver response to known driver responses at different leakage conditions. - measure a property of a first signal that is applied to the speaker (SP); - measure a property of a second signal that is detected by the error microphone (FB_MIC); - determine a driver response between the speaker (SP) and the error microphone (FE_MIC) by calculating the driver response from the properties of the first and the second signal; and - estimate a leakage condition by comparing the determined driver response to known driver responses at different leakage conditions.
A method for detecting and quantifying a metabolite or breakdown product of PEG in a sample, said method comprising; combining a sample obtained, said sample containing PEG 3350, with an aqueous hydroxide containing salt, and pentafluorobenzoyl chloride dissolved in an organic solvent thus producing a biphasic liquid system, said biphasic liquid system comprising a pentafluorobenzoate ester derivative, said pentafluorobenzoate ester derivative comprising ethane-1,2-diyl bis(2,3,4,5,6-pentafluorobenzoate) or 2,2'-oxybis(ethane-2,1-diyl) bis(2,3,4,5,6-pentafluorobenzoate); separating a liquid phase supernatant from said biphasic liquid system; and analyzing said supernatant using liquid chromatography and mass spectrometry (LC/MS) to detect a retention time of said pentafluorobenzoate ester derivative; wherein ethylene glycol in said sample is quantified at a concentration between 100 ng/mL and 10000 ng/mL of ethylene glycol per sample based on said retention time of said pentafluorobenzoate ester derivative; and wherein diethylene glycol is quantified in a concentration between 20 ng/mL and 2000 ng/mL of diethylene glycol per sample based on said retention time of said pentafluorobenzoate ester derivative.
A tool for use by a surgeon for operating a basket device for capturing an object to be removed from a body of a human or an animal, the tool comprising: a housing having a longitudinal axis and including a passage ; a first controller including a first portion located in the passage in the housing and a second portion extending from the housing, wherein the first controller is adapted to be coupled to the basket device for selectively controlling the basket device and wherein the first controller is axially movable in the passage of the housing for moving the basket device between a first, closed position and a second, open position, and wherein the first controller is rotationally movable in the passage of the housing for rotating the basket device when in the second, open position; and an end surface coupled to the second portion of the first controller, wherein the end surface is configured to move axially with the first controller , and wherein the end surface is configured to move independently rotationally of the first controller for the end surface to remain rotationally stationary while the first controller is rotated. a housing having a longitudinal axis and including a passage ; a first controller including a first portion located in the passage in the housing and a second portion extending from the housing, wherein the first controller is adapted to be coupled to the basket device for selectively controlling the basket device and wherein the first controller is axially movable in the passage of the housing for moving the basket device between a first, closed position and a second, open position, and wherein the first controller is rotationally movable in the passage of the housing for rotating the basket device when in the second, open position; and an end surface coupled to the second portion of the first controller, wherein the end surface is configured to move axially with the first controller , and wherein the end surface is configured to move independently rotationally of the first controller for the end surface to remain rotationally stationary while the first controller is rotated.
Escherichia coli strain with recA1, gyrA96, thi-1, glnV44, relA1, hsdR17, endA1, lacZ, nanKETA, lacA, melA, wcaJ, mdoH, ptsG, manX, manY, and pfkA genes are inactivated.
Method for controlling the movement of a three-point hydraulic lift which is arranged on a tractor , wherein movements of an actuated operator control lever are converted into movements of the three-point hydraulic lift in such a manner that - upon a first actuation movement (X) of the operator control lever , the attachment is moved along an exclusively translational movement path parallel to a vertical direction of the tractor , and - upon a second actuation movement (Z) of the operator control lever , the attachment is pivoted along an exclusively rotational movement path with respect to a pivot axis . - upon a first actuation movement (X) of the operator control lever , the attachment is moved along an exclusively translational movement path parallel to a vertical direction of the tractor , and - upon a second actuation movement (Z) of the operator control lever , the attachment is pivoted along an exclusively rotational movement path with respect to a pivot axis .
A solid dispersion of (S)-[2-chloro-4-fluoro-5-(7-morpholin-4-ylquinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl)methanol, or a pharmaceutically acceptable salt thereof, in a polymeric matrix comprising or consisting of a homopolymer or copolymer of polyvinylpyrrolidone.
Arrangement comprising a centrifugal separator of liquid and steam and a household apparatus such as a steam oven, laundry dryer, distillation apparatus, steam iron, steam cleaner and similar, comprising a steam generator (G), characterized in that the centrifugal separator is formed as a single piece separator comprising a central cylindrical section which at the first end thereof, the bottom end that is, changes over via an eccentric reducing section into a liquid discharge section , and which at the opposite end thereof, the top end that is, changes over via a reducing section into a steam discharge section of the steam, wherein in the area under said reducing section an inlet pipe is attached to said central cylindrical section through which a mixture of liquid and steam to be separated is directed from the steam generator (G) into said section , wherein said inlet pipe is attached tangentially to said section and, with regard to the longitudinal axis of the section , slanted under an angle in the direction toward said eccentric reducing section and said liquid discharge section , respectively, and wherein the inlet pipe is formed with a conical reduction at the location of the attachment of the inlet pipe to the section and on the side of the section which is opposite to the tangential side to enable for the said mixture of the liquid and the steam to be directed into the wall of said section .
An electronic module , comprising - a semiconductor package , comprising - a die carrier ; - a semiconductor die disposed on the die carrier ; - at least one electrical conductor connected to the semiconductor die ; and - an encapsulant covering the die carrier , the semiconductor die , and the electrical conductor so that a portion of the electrical conductor extends to the outside of the encapsulant ; - an interposer layer , wherein the semiconductor package is disposed on the interposer layer ; and - a heat sink through which a cooling medium can flow, wherein the interposer layer is disposed on the heatsink , characterized in that the interposer layer is one of an isolated metal substrate (IMS), a direct copper bond (DCB), or an active metal braze (AMB), and/or the interposer layer is embedded in an upper main face of the heatsink . - a semiconductor package , comprising - a die carrier ; - a semiconductor die disposed on the die carrier ; - at least one electrical conductor connected to the semiconductor die ; and - an encapsulant covering the die carrier , the semiconductor die , and the electrical conductor so that a portion of the electrical conductor extends to the outside of the encapsulant ; - a die carrier ; - a semiconductor die disposed on the die carrier ; - at least one electrical conductor connected to the semiconductor die ; and - an encapsulant covering the die carrier , the semiconductor die , and the electrical conductor so that a portion of the electrical conductor extends to the outside of the encapsulant ; - an interposer layer , wherein the semiconductor package is disposed on the interposer layer ; and - a heat sink through which a cooling medium can flow, wherein the interposer layer is disposed on the heatsink , the interposer layer is one of an isolated metal substrate (IMS), a direct copper bond (DCB), or an active metal braze (AMB), and/or the interposer layer is embedded in an upper main face of the heatsink .
Single-piece exchanger allowing the transfer of heat between a first fluid and a second fluid, comprising, from bottom to top when considering the direction of manufacture: - at least two distribution zones and ; - at least two collection zones and ; - at least two inlet connectors and adjoining the distribution zones and at least two outlet connectors and adjoining the collection zones; - at least one inlet situated on each inlet connector; - at least one outlet situated on each outlet connector; - an exchange zone allowing a transfer of heat between the canals for the first fluid and the canals for the second fluid; with each connector comprising supports in their internal upper part. - at least two distribution zones and ; - at least two collection zones and ; - at least two inlet connectors and adjoining the distribution zones and at least two outlet connectors and adjoining the collection zones; - at least one inlet situated on each inlet connector; - at least one outlet situated on each outlet connector; - an exchange zone allowing a transfer of heat between the canals for the first fluid and the canals for the second fluid;