A dry powder inhaler with a distal end and a proximal end, the dry powder inhaler comprising: at least one inlet and at least one outlet , wherein a communication between said at least one inlet and said at least one outlet at least comprises a mixing and deaggregation chamber and at least two dosage communications between the at least one inlet and the chamber , wherein the at least one outlet is arranged at a first end of the dry powder drug inhaler , while the at least one inlet is arranged at a zone in an opposite second end of the dry powder inhaler , wherein the first end is the proximal end and the opposite, second end is the distal end; a first medicament reservoir for housing a dry powder first medicament; a second medicament reservoir for housing a dry powder second medicament; a dosage mechanism for arranging at least one dose of a medicament between the at least one inlet and the chamber , such that said at least one dose may be delivered upon inhalation at said at least one outlet through said communications ; wherein the dosage mechanism is configured to withdraw an inhaler metered dose of the dry powder in the first and second medicament reservoirs in a dose collecting position from the reservoirs into said dosage communications in a dose administering position; wherein the dosage mechanism comprises a dose disc with at least one opening per reservoir , wherein the dose disc may be rotated between the dose collecting position, wherein the openings are positioned in the reservoirs , and the dose administering position, wherein the openings communicate with said dosage communications ; wherein said dosage communications have directions when entering the chamber for allowing jet streams through communications to interact, such that medicament in said jet streams can interact to deaggregate; characterised in that said dosage communications have intersecting directions when entering the chamber . at least one inlet and at least one outlet , wherein a communication between said at least one inlet and said at least one outlet at least comprises a mixing and deaggregation chamber and at least two dosage communications between the at least one inlet and the chamber , wherein the at least one outlet is arranged at a first end of the dry powder drug inhaler , while the at least one inlet is arranged at a zone in an opposite second end of the dry powder inhaler , wherein the first end is the proximal end and the opposite, second end is the distal end; a first medicament reservoir for housing a dry powder first medicament; a second medicament reservoir for housing a dry powder second medicament; a dosage mechanism for arranging at least one dose of a medicament between the at least one inlet and the chamber , such that said at least one dose may be delivered upon inhalation at said at least one outlet through said communications ; wherein the dosage mechanism is configured to withdraw an inhaler metered dose of the dry powder in the first and second medicament reservoirs in a dose collecting position from the reservoirs into said dosage communications in a dose administering position; wherein the dosage mechanism comprises a dose disc with at least one opening per reservoir , wherein the dose disc may be rotated between the dose collecting position, wherein the openings are positioned in the reservoirs , and the dose administering position, wherein the openings communicate with said dosage communications ; wherein said dosage communications have directions when entering the chamber for allowing jet streams through communications to interact, such that medicament in said jet streams can interact to deaggregate; characterised in that said dosage communications have intersecting directions when entering the chamber . <EOS>