A system for directing a device to a target region within a cavity of a body, the system comprising a first catheter comprising a handle at a proximate end, an expandable cage at a distal end, and a lumen therebetween, an outer sheath axially movable to alternatively cover and expose the expandable cage to permit the expandable cage to move from a collapsed delivery mode to an expanded deployed mode, the expandable cage comprising a plurality of members that expand to engage a wall of the body cavity to stabilize the expandable cage within the cavity, the expandable cage being rotatable within the cavity when the handle of the first catheter is rotated; a second catheter positioned within the lumen of the first catheter , the second catheter comprising a proximal end that passes through the handle of the first catheter ; characterized in that the second catheter has a distal end that passes through a hub , the second catheter comprising a lumen therethrough, the second catheter being axially and rotationally movable within the lumen of the first catheter in association with axial and rotational movement of the expandable cage ; a plurality of pairs of wires , each wire having a first end secured within the handle of the first catheter and a second opposite end secured at the hub of the second catheter , each pair of wires being movable in conjunction with each other by manipulation of the handle so as to move the hub , and thereby the distal end of the second catheter , a first pair of wires movable to move the hub in a first direction and a second pair of wires movable to move the hub in a second direction; whereby, through manipulation of the handle and wires , the distal end of the second catheter may be rotated within the cavity while moved in the first and second direction. a first catheter comprising a handle at a proximate end, an expandable cage at a distal end, and a lumen therebetween, an outer sheath axially movable to alternatively cover and expose the expandable cage to permit the expandable cage to move from a collapsed delivery mode to an expanded deployed mode, the expandable cage comprising a plurality of members that expand to engage a wall of the body cavity to stabilize the expandable cage within the cavity, the expandable cage being rotatable within the cavity when the handle of the first catheter is rotated; a second catheter positioned within the lumen of the first catheter , the second catheter comprising a proximal end that passes through the handle of the first catheter ; characterized in that the second catheter has a distal end that passes through a hub , the second catheter comprising a lumen therethrough, the second catheter being axially and rotationally movable within the lumen of the first catheter in association with axial and rotational movement of the expandable cage ; a plurality of pairs of wires , each wire having a first end secured within the handle of the first catheter and a second opposite end secured at the hub of the second catheter , each pair of wires being movable in conjunction with each other by manipulation of the handle so as to move the hub , and thereby the distal end of the second catheter , a first pair of wires movable to move the hub in a first direction and a second pair of wires movable to move the hub in a second direction; whereby, through manipulation of the handle and wires , the distal end of the second catheter may be rotated within the cavity while moved in the first and second direction. <EOS>