mhurhangee/patent-ind-claim-en huggingface dataset:
A method for predicting whether an anti-cancer effect is likely to be produced in a cancer of a subject by a PI3Kα inhibitor comprising: measuring the PIK3CA mutant allele fraction in a sample from the subject prior to the PI3Kα inhibitor treatment, measuring the PIK3CA mutant allele fraction in a sample from the subject during the PI3Kα inhibitor treatment, and predicting that it is less likely that the PI3Kα inhibitor is having an anti-cancer effect on the cancer when the PIK3CA mutant allele fraction in the sample obtained during the PI3Kα inhibitor treatment decreased less than 25% or increased as compared to the PIK3CA mutant allele fraction in the sample obtained prior to the PI3Kα inhibitor treatment, wherein the PI3Kα inhibitor is selected from the group consisting of BYL719, INK-1114, INK-1117, NVP-BYL719, SRX2523, LY294002, PIK-75, PKI-587, A66, and CH5132799, and wherein the PIK3CA mutant allele fraction is the ratio of the copies of a PIK3CA mutant allele to the copies of a PIK3CA wild-type allele. measuring the PIK3CA mutant allele fraction in a sample from the subject prior to the PI3Kα inhibitor treatment, measuring the PIK3CA mutant allele fraction in a sample from the subject during the PI3Kα inhibitor treatment, and predicting that it is less likely that the PI3Kα inhibitor is having an anti-cancer effect on the cancer when the PIK3CA mutant allele fraction in the sample obtained during the PI3Kα inhibitor treatment decreased less than 25% or increased as compared to the PIK3CA mutant allele fraction in the sample obtained prior to the PI3Kα inhibitor treatment, wherein the PI3Kα inhibitor is selected from the group consisting of BYL719, INK-1114, INK-1117, NVP-BYL719, SRX2523, LY294002, PIK-75, PKI-587, A66, and CH5132799, and wherein the PIK3CA mutant allele fraction is the ratio of the copies of a PIK3CA mutant allele to the copies of a PIK3CA wild-type allele.
A door-locking device particularly for electrical household appliances, comprising an actuator ; a locking pin controllable by the actuator and adapted to cooperate with a movable latching slider to lock a door of an electrical household appliance, said locking pin being movable between a rest position, wherein the locking pin allows the latching slider to move, and a lock position, wherein the locking pin prevents said latching slider from moving; a detection switch able to switch between an open position and a closed position following a movement of the latching slider , said detection switch comprising a fixed contact element and a movable contact element resiliently stressed in closure towards the fixed contact element , and a movable control member interacting with the movable contact element for closing/opening the detection switch ; wherein the control member is adapted to cooperate with the latching slider and is also movable by effect of a movement of the locking pin ; wherein the door-locking device is characterized in that the control member is movable along a direction parallel to the direction of movement of the latching slider due to a movement of the locking pin .
A beer maker comprising: a fermentation tank assembly including a fermentation tank having an opening formed therein and a fermentation tank cover covering the opening ; the fermentation tank assembly is configured to accommodate a beer brewing pack through the opening ; a main flow path connected to the fermentation tank assembly ; a beer extraction flow path connected to the main flow path ; characterized by an air supply flow path connected to the inside of the fermentation tank to supply air between the beer brewing pack and the fermentation tank ; and an air relief valve disposed in the air supply flow path . a fermentation tank assembly including a fermentation tank having an opening formed therein and a fermentation tank cover covering the opening ; the fermentation tank assembly is configured to accommodate a beer brewing pack through the opening ; a main flow path connected to the fermentation tank assembly ; a beer extraction flow path connected to the main flow path ; characterized by an air supply flow path connected to the inside of the fermentation tank to supply air between the beer brewing pack and the fermentation tank ; and an air relief valve disposed in the air supply flow path .
A light-source device comprising: a light source including a light-emitting element arranged to emit light having an oscillation wavelength; a light detector arranged to receive light emitted from the light source ; an estimation unit arranged to estimate the oscillation wavelength of light emitted by the light-emitting element ; and a detector arranged to detect an ambient temperature of the light source ; wherein the estimation unit is arranged to estimate the oscillation wavelength of the light based on an amount of light received by the light detector and the ambient temperature detected by the detector ; wherein the light-source device , further comprises a signal processor arranged to temporally average a signal according to the amount of light received by the light detector , wherein the estimation unit is arranged to estimate the wavelength of the light based on the signal temporally averaged by the signal processor ; and wherein the estimation unit is arranged to estimate the wavelength of the light based on a formula of λ = λ + α × (T a - T a ) + β × (P - P ), where λ is the wavelength of the light, λ is a reference wavelength, α is a temperature coefficient, T a is a current ambient temperature, T a is an ambient temperature on measurement of the reference wavelength, β is light-amount coefficient, P is the temporally averaged amount of light emission, and P is an amount of light emission on measurement of the reference wavelength. a light source including a light-emitting element arranged to emit light having an oscillation wavelength; a light detector arranged to receive light emitted from the light source ; an estimation unit arranged to estimate the oscillation wavelength of light emitted by the light-emitting element ; and a detector arranged to detect an ambient temperature of the light source ; wherein the estimation unit is arranged to estimate the oscillation wavelength of the light based on an amount of light received by the light detector and the ambient temperature detected by the detector ; wherein the light-source device , further comprises a signal processor arranged to temporally average a signal according to the amount of light received by the light detector , wherein the estimation unit is arranged to estimate the wavelength of the light based on the signal temporally averaged by the signal processor ; and wherein the estimation unit is arranged to estimate the wavelength of the light based on a formula of λ = λ + α × (T a - T a ) + β × (P - P ), where λ is the wavelength of the light, λ is a reference wavelength, α is a temperature coefficient, T a is a current ambient temperature, T a is an ambient temperature on measurement of the reference wavelength, β is light-amount coefficient, P is the temporally averaged amount of light emission, and P is an amount of light emission on measurement of the reference wavelength.
A process for preparing N-(aminoiminomethyl)-2-aminoacetic acid comprising N-(aminoiminomethyl)-2-aminoacetic acid in a thermodynamically metastable crystal modification, wherein the thermodynamically metastable crystal modification shows in the X-ray powder diffractogram of the crystal modification when using Cu-Kα radiation the strongest reflection bands at 2Θ = 20.2 ° and 23.3 ° and 23.8 ° and 25.3 ° with a measurement accuracy of +/- 0.2 °, characterized in that N-(aminoiminomethyl)-2-aminoacetic acid is crystallized from a water-containing solution in the presence of at least one guanidine compound of formula (I), wherein formula (I) represents: where radicals R 1 , R 2 as well as indices m 1 , m 2 in formula (I) independently of one another mean: R 1 , R 2 = independently of one another hydrogen or C1 to C4 alkyl, m 1 , m 2 = independently of one another 1, 2 or 3, wherein the guanidine compounds of formula (I) are present in an amount of at least 0.01 wt-% (based on the total weight of the solution). where radicals R 1 , R 2 as well as indices m 1 , m 2 in formula (I) independently of one another mean: R 1 , R 2 = independently of one another hydrogen or C1 to C4 alkyl, m 1 , m 2 = independently of one another 1, 2 or 3, R 1 , R 2 = independently of one another hydrogen or C1 to C4 alkyl, m 1 , m 2 = independently of one another 1, 2 or 3, wherein the guanidine compounds of formula (I) are present in an amount of at least 0.01 wt-% (based on the total weight of the solution).
Cutting wheel system for a dredging device, comprising a cutting wheel and a cutting wheel drive system , whereby the cutting wheel comprises at least two cutting element rings , which rings are positioned at a distance from each other in parallel planes whereby the cutting element rings have coaxial rotation axes , whereby a suction tube can be positioned between the two cutting element rings , whereby the cutting wheel drive system is arranged to rotate the cutting wheel about the coaxial rotation axes, wherein the cutting wheel system further comprises connecting arms for mounting the cutting wheel in a rotatable manner to the dredging device, characterized in that the connecting arms are moveable with respect to each other between a closed position wherein the connecting arms engage the cutting wheel from opposite sides of the cutting wheel, and an open position wherein the cutting wheel is released from the connecting arms, and further comprising a retaining device which is arranged to keep the cutting wheel in place when the connecting arms are in the open position.
A method of providing security in a Fine Timing Measurement, FTM, session between an initiating wireless station and a responding wireless station, the method comprising: negotiating at least one value over a secure network, the at least one value comprising: a random sequence of nonce values, or a first predetermined value; sending, with the initiating wireless station, an FTM request, wherein the FTM request includes at least one security feature, wherein the at least one security feature of the FTM request comprises: at least a portion of the random sequence of nonce values, or a first media access control, MAC, address, wherein at least a portion of the first MAC address comprises the first predetermined value; receiving, at the initiating wireless station, an FTM frame, wherein the FTM frame comprises a response to the at least one security feature; determining, at the initiating wireless station, an authenticity of the response to the at least one security feature; and completing the FTM session. negotiating at least one value over a secure network, the at least one value comprising: a random sequence of nonce values, or a first predetermined value; a random sequence of nonce values, or a first predetermined value; sending, with the initiating wireless station, an FTM request, wherein the FTM request includes at least one security feature, wherein the at least one security feature of the FTM request comprises: at least a portion of the random sequence of nonce values, or a first media access control, MAC, address, wherein at least a portion of the first MAC address comprises the first predetermined value; at least a portion of the random sequence of nonce values, or a first media access control, MAC, address, wherein at least a portion of the first MAC address comprises the first predetermined value; receiving, at the initiating wireless station, an FTM frame, wherein the FTM frame comprises a response to the at least one security feature; determining, at the initiating wireless station, an authenticity of the response to the at least one security feature; and completing the FTM session.
A resin foamed body made of flexible resin, wherein the resin foamed body entirely includes a skeleton part , characterized in that the skeleton part includes a plurality of bone parts , and a plurality of connection parts connecting end parts of the plurality of bone parts , the plurality of bone parts each include a bone constant part (2B1) extending while keeping cross-sectional area substantially constant, and a bone change part (2B2) extending from the bone constant part (2B1) to the corresponding connection part while gradually increasing cross-sectional area, and as for the plurality of bone parts , in each of the plurality of bone parts, an average value AV(A0/A1) of a ratio A0/A1 of cross-sectional area A0 of the bone change part (2B2) of each bone part at an edge on the bone constant part (2B1) side relative to cross-sectional area A1 of the bone change part (2B2) at an edge on the connection part side satisfies 0.15 ≤ AV A 0 / A 1 < 0.5 . a plurality of bone parts , and a plurality of connection parts connecting end parts of the plurality of bone parts , the plurality of bone parts each include a bone constant part (2B1) extending while keeping cross-sectional area substantially constant, and a bone change part (2B2) extending from the bone constant part (2B1) to the corresponding connection part while gradually increasing cross-sectional area, and as for the plurality of bone parts , in each of the plurality of bone parts, an average value AV(A0/A1) of a ratio A0/A1 of cross-sectional area A0 of the bone change part (2B2) of each bone part at an edge on the bone constant part (2B1) side relative to cross-sectional area A1 of the bone change part (2B2) at an edge on the connection part side satisfies 0.15 ≤ AV A 0 / A 1 < 0.5 .
An automated method of manufacturing wing junction parts comprising: (a) milling aircraft wing junction parts with overmaterial ; (b) scanning the wing junction parts; ; (c) using at least one processor, comparing the parts scans with a model using a B-Spline algorithm; (d) based on the comparison between the parts scans and the model, generating a trajectory milling program ; to fill gaps between the wing junction parts using a new generated surface using a Multi-section procedure from B-Spline; and (e) further milling the wing junction parts ; using the trajectory milling program to remove overmaterial, thereby minimizing gaps between parts and eliminating a corresponding need for shimming to fill said gaps. (a) milling aircraft wing junction parts with overmaterial ; (b) scanning the wing junction parts; ; (c) using at least one processor, comparing the parts scans with a model using a B-Spline algorithm; (d) based on the comparison between the parts scans and the model, generating a trajectory milling program ; to fill gaps between the wing junction parts using a new generated surface using a Multi-section procedure from B-Spline; and (e) further milling the wing junction parts ; using the trajectory milling program to remove overmaterial, thereby minimizing gaps between parts and eliminating a corresponding need for shimming to fill said gaps.
A compact system for scanning electromagnetic imaging radiation, comprising: electromagnetic radiation sources ; a drive electronics system configured to generate a pixel modulation signal to modulate the luminance of the electromagnetic radiation sources ; a first waveguide , a second waveguide and a plurality of additional waveguides, each of which is operatively coupled to at least one of the electromagnetic radiation sources and configured such that output from the first , second and plurality of additional waveguides is luminance modulated; a first scanning actuator , a second scanning actuator, and a plurality of additional scanning actuators, each being operatively coupled to and configured to uniquely and independently physically displace each of the first , second and plurality of additional waveguides such that the first , second and plurality of additional waveguides may be actuated independently and scanned along one or more axes to form at least a portion of an image; and wherein each of the first , second and plurality of additional waveguides is an optical fiber, characterized in that the first , second and plurality of additional waveguides are arranged in a hexagonally packed tiled two-dimensional array configuration and in that the scanned images from each of the first , second and plurality of additional waveguides partially overlap at intersecting regions and are luminance modulated in said intersecting regions to provide greater luminance uniformity. electromagnetic radiation sources ; a drive electronics system configured to generate a pixel modulation signal to modulate the luminance of the electromagnetic radiation sources ; a first waveguide , a second waveguide and a plurality of additional waveguides, each of which is operatively coupled to at least one of the electromagnetic radiation sources and configured such that output from the first , second and plurality of additional waveguides is luminance modulated; a first scanning actuator , a second scanning actuator, and a plurality of additional scanning actuators, each being operatively coupled to and configured to uniquely and independently physically displace each of the first , second and plurality of additional waveguides such that the first , second and plurality of additional waveguides may be actuated independently and scanned along one or more axes to form at least a portion of an image; and wherein each of the first , second and plurality of additional waveguides is an optical fiber, characterized in that the first , second and plurality of additional waveguides are arranged in a hexagonally packed tiled two-dimensional array configuration and in that the scanned images from each of the first , second and plurality of additional waveguides partially overlap at intersecting regions and are luminance modulated in said intersecting regions to provide greater luminance uniformity.
A method of wireless communication by a base station configured to provide a cell, and configured to send at least one narrowband reference signal, NRS, in at least one paging occasion, PO, on a narrowband control channel, the method characterized by : calculating a scheduling value based on a number of groups associated with a set of user equipments, UEs operating on the cell, wherein the scheduling value is calculated based on a rate value R, the rate value R being associated with a periodicity at which the at least one NRS is sent in the at least one PO, wherein the scheduling value is calculated further based on a maximum between 1 and the rate value R divided by the number of groups; sending , the at least one NRS in the at least one PO based on the calculated scheduling value; and sending in the cell, at least one system information block, SIB, wherein the at least one SIB indicates the number of groups associated with the set of UEs and the rate value R. calculating a scheduling value based on a number of groups associated with a set of user equipments, UEs operating on the cell, wherein the scheduling value is calculated based on a rate value R, the rate value R being associated with a periodicity at which the at least one NRS is sent in the at least one PO, wherein the scheduling value is calculated further based on a maximum between 1 and the rate value R divided by the number of groups; sending , the at least one NRS in the at least one PO based on the calculated scheduling value; and sending in the cell, at least one system information block, SIB, wherein the at least one SIB indicates the number of groups associated with the set of UEs and the rate value R.
A neonatal care system comprising: a platform for supporting an infant; at least one load cell configured to sense a weight of the infant supported on the platform; an inclinometer configured to measure an angle of the platform; a controller configured to determine an infant weight based on the sensed weight; characterised in that it further comprises a motor configured to control an angle of the platform , wherein the controller is configured to control the motor based on the measured angle of the platform to level the platform prior to determining the infant weight. a platform for supporting an infant; at least one load cell configured to sense a weight of the infant supported on the platform; an inclinometer configured to measure an angle of the platform; a controller configured to determine an infant weight based on the sensed weight; characterised in that it further comprises a motor configured to control an angle of the platform , wherein the controller is configured to control the motor based on the measured angle of the platform to level the platform prior to determining the infant weight.
A wave energy conversion apparatus, comprising: a flotation device adapted to float on the surface of a body of water having a wave base; a Venturi tube having a Venturi channel including an upper mouth, a lower mouth and a constricted region between the upper and lower mouths, the Venturi tube being connected to the flotation device such that when the apparatus is in the body of water, the Venturi tube is positioned below the flotation device and at a distance below the surface of the body of water, and water flows downwardly in the Venturi channel and through the constricted region when the flotation device moves upwardly by wave action in the body of water and water flows upwardly in the Venturi channel and through the constricted region when the flotation device moves downwardly by wave action in the body of water; a turbine in the Venturi channel; and at least one of a first extension cuff extending upwardly from the upper mouth and a second extension cuff extending downwardly from the lower mouth. a flotation device adapted to float on the surface of a body of water having a wave base; a Venturi tube having a Venturi channel including an upper mouth, a lower mouth and a constricted region between the upper and lower mouths, the Venturi tube being connected to the flotation device such that when the apparatus is in the body of water, the Venturi tube is positioned below the flotation device and at a distance below the surface of the body of water, and water flows downwardly in the Venturi channel and through the constricted region when the flotation device moves upwardly by wave action in the body of water and water flows upwardly in the Venturi channel and through the constricted region when the flotation device moves downwardly by wave action in the body of water; a turbine in the Venturi channel; and at least one of a first extension cuff extending upwardly from the upper mouth and a second extension cuff extending downwardly from the lower mouth.
A light emitting apparatus for dermatological treatment comprising a housing structure for housing a light emitting source, a fan and a duct, the light emitting source arranged to emit light energy to external of the device, the fan configured for directing air heated by operation of the light emitting source into the duct, the duct being arranged to direct heated air in an airstream pathway from an outlet port of a distal end of the duct and through an aperture in the housing structure , wherein the housing structure and the duct are relatively arranged such that no part of the housing structure extends into the airstream pathway in order to minimise heat exchange from the heated air to the housing structure characterised in that the distal end of the duct is insulated from the housing structure .
A modified conjugated diene-based polymer comprising: a repeating unit derived from a conjugated diene-based monomer; and a functional group derived from a modifier, wherein, if measured by differential scanning calorimetry (DSC), a difference between a glass transition onset temperature (T g-on ) and a glass transition offset temperature (T g-off ), which arise glass transition, is 20°C to 30°C.