An optical method for determining morphological parameters of a skin tissue lesion from reflectance images of the skin tissue lesion, the method comprising the steps of: generating a reflectance image of a skin tissue lesion using an optical transfer diagnosis device; determining a lesion border from the reflectance image of the lesion from a visible channel by identifying the regions in which a gradient of reflected intensity has its largest values; measuring a size of the lesion from the number of pixels inside the lesion border; determining a histogram-width, that gives a measure of inhomogeneity of the reflectance image of the lesion; capturing a relative moment of inertia of the lesion by: defining the distribution of light absorptance across the lesion as a mass distribution and calculating a center of mass and a moment of inertia about an axis normal to the tissue through the center of mass for the lesion; calculating a total mass for the lesion as an average light absorptance of the lesion; and calculating the relative moment of inertia as the moment of inertia of the lesion relative to a moment of inertia of a homogenous circular disk having a total mass equal to the total mass of the lesion and a diameter equal to the average diameter of the lesion; determining a center distance representing a physical distance between a geometrical center of the lesion and the center of mass of absorptance; determining a fractal dimension of the lesion which describes the complexity of its border; determining an asphericity of the lesion; and determining a relative border length of the lesion as the ratio of the border length of a circle with the same area as the lesion to the actual border length of the lesion. generating a reflectance image of a skin tissue lesion using an optical transfer diagnosis device; determining a lesion border from the reflectance image of the lesion from a visible channel by identifying the regions in which a gradient of reflected intensity has its largest values; measuring a size of the lesion from the number of pixels inside the lesion border; determining a histogram-width, that gives a measure of inhomogeneity of the reflectance image of the lesion; capturing a relative moment of inertia of the lesion by: defining the distribution of light absorptance across the lesion as a mass distribution and calculating a center of mass and a moment of inertia about an axis normal to the tissue through the center of mass for the lesion; calculating a total mass for the lesion as an average light absorptance of the lesion; and calculating the relative moment of inertia as the moment of inertia of the lesion relative to a moment of inertia of a homogenous circular disk having a total mass equal to the total mass of the lesion and a diameter equal to the average diameter of the lesion; defining the distribution of light absorptance across the lesion as a mass distribution and calculating a center of mass and a moment of inertia about an axis normal to the tissue through the center of mass for the lesion; calculating a total mass for the lesion as an average light absorptance of the lesion; and calculating the relative moment of inertia as the moment of inertia of the lesion relative to a moment of inertia of a homogenous circular disk having a total mass equal to the total mass of the lesion and a diameter equal to the average diameter of the lesion; determining a center distance representing a physical distance between a geometrical center of the lesion and the center of mass of absorptance; determining a fractal dimension of the lesion which describes the complexity of its border; determining an asphericity of the lesion; and determining a relative border length of the lesion as the ratio of the border length of a circle with the same area as the lesion to the actual border length of the lesion. <EOS>