mhurhangee/patent-ind-claim-en huggingface dataset:
A method for producing an alkaline earth carbonate comprising; introducing a primary raw material comprising a first extractable material and a second extractable material to a vessel, wherein the first extractable material comprises an alkaline earth oxide or hydroxide; contacting the primary raw material with an organic amine-containing lixiviant to generate a reaction mixture, wherein the lixiviant is provided in sub-stoichiometric amounts relative to the alkaline earth; contacting, in the vessel, the reaction mixture with carbon dioxide to form a slurry, wherein the slurry comprises an extracted raw material and an alkaline earth carbonate precipitate, wherein the extracted raw material is enriched in the second extractable material relative to the primary raw material; transferring the slurry to a separation unit to generate a first product stream comprising the extracted raw material, a second product stream comprising the alkaline earth carbonate precipitate, and a third product stream comprising a mother liquor; collecting the first product stream and processing the extracted raw material to extract the second extractable material; and, returning at least a portion of the third product stream to the vessel, wherein the mother liquor comprises a regenerated organic amine-containing lixiviant. introducing a primary raw material comprising a first extractable material and a second extractable material to a vessel, wherein the first extractable material comprises an alkaline earth oxide or hydroxide; contacting the primary raw material with an organic amine-containing lixiviant to generate a reaction mixture, wherein the lixiviant is provided in sub-stoichiometric amounts relative to the alkaline earth; contacting, in the vessel, the reaction mixture with carbon dioxide to form a slurry, wherein the slurry comprises an extracted raw material and an alkaline earth carbonate precipitate, wherein the extracted raw material is enriched in the second extractable material relative to the primary raw material; transferring the slurry to a separation unit to generate a first product stream comprising the extracted raw material, a second product stream comprising the alkaline earth carbonate precipitate, and a third product stream comprising a mother liquor; collecting the first product stream and processing the extracted raw material to extract the second extractable material; and, returning at least a portion of the third product stream to the vessel, wherein the mother liquor comprises a regenerated organic amine-containing lixiviant.
A rotating dental attachment comprising a base piece and an angled top piece wherein the angled top piece is configured to be coupled either by pressure or friction to the base piece , in such a way that there is an existing pressure-friction between the base piece and the angled top piece , as a result of the elasticity of the base piece ; wherein the angled top piece comprises an inner thread that has a longitudinal axis angled with respect to the longitudinal axis of the base piece when said pieces are coupled; wherein the angled top piece is also configured to be rotated 360° on the base piece , the base piece being configured to be placed on and fastened onto an implant ; and wherein the inner thread is configured for bolting a dental superstructure. wherein the angled top piece is configured to be coupled either by pressure or friction to the base piece , in such a way that there is an existing pressure-friction between the base piece and the angled top piece , as a result of the elasticity of the base piece ; wherein the angled top piece comprises an inner thread that has a longitudinal axis angled with respect to the longitudinal axis of the base piece when said pieces are coupled; wherein the angled top piece is also configured to be rotated 360° on the base piece , the base piece being configured to be placed on and fastened onto an implant ; and wherein the inner thread is configured for bolting a dental superstructure.
A method of identifying a population of immunosuppressive regulatory T-cells, the method comprising: screening a sample comprising a population of T-cells to detect a level of cellular expression of at least three different biomarkers, the at least three different biomarkers including a CD4 biomarker, a CD25 biomarker and a CD6 biomarker; wherein detection of a subpopulation of T-cells comprising a CD4 + CD25 + CD6 low/- expression pattern identifies the population of immunosuppressive regulatory T-cells in the sample. screening a sample comprising a population of T-cells to detect a level of cellular expression of at least three different biomarkers, the at least three different biomarkers including a CD4 biomarker, a CD25 biomarker and a CD6 biomarker; wherein detection of a subpopulation of T-cells comprising a CD4 + CD25 + CD6 low/- expression pattern identifies the population of immunosuppressive regulatory T-cells in the sample.
An ex vivo method for testing cellular responsiveness of primary tumor cell populations to a drug or combination of drugs that comprises: i) submit a whole sample from a subject selected from: peripheral blood (PB), or bone marrow (BN), or lymph node (LN) to a separation process to isolate an Artificial Environment (AE) consisting of a plasma fraction, an erythrocyte fraction or a combination thereof, free from leukocytes, ii) mix the leukocyte-free AE obtained in the previous step with a primary tumor cell population, iii) add to the mixture of step ii) at least one drug to be tested, iv) incubate the mixture obtained in step iii) during from 2 hours to 14 days to allow the drug tested to exert any activity it might have on the primary tumor cell population, v) assess the viability and/or proliferation of the primary tumor cell population in the presence or absence of the drug tested, vi) produce comparative data on viability and/or on proliferation of the primary tumor cell population between the assessment made in presence and in absence of the drug tested and relate the data obtained to values indicative of drug activity for reducing/increasing viability and/or proliferation of the primary tumor cell population. i) submit a whole sample from a subject selected from: peripheral blood (PB), or bone marrow (BN), or lymph node (LN) to a separation process to isolate an Artificial Environment (AE) consisting of a plasma fraction, an erythrocyte fraction or a combination thereof, free from leukocytes, ii) mix the leukocyte-free AE obtained in the previous step with a primary tumor cell population, iii) add to the mixture of step ii) at least one drug to be tested, iv) incubate the mixture obtained in step iii) during from 2 hours to 14 days to allow the drug tested to exert any activity it might have on the primary tumor cell population, v) assess the viability and/or proliferation of the primary tumor cell population in the presence or absence of the drug tested, vi) produce comparative data on viability and/or on proliferation of the primary tumor cell population between the assessment made in presence and in absence of the drug tested and relate the data obtained to values indicative of drug activity for reducing/increasing viability and/or proliferation of the primary tumor cell population.
Method for weighing pharmaceutical containers nested in a carrier , in which at least one of the nested containers is weighed by means of a weighing device , wherein a relative movement between the at least one pharmaceutical container and the carrier is caused in order to release the pharmaceutical container from the carrier to increase the weighing accuracy, characterized in that the relative movement is caused by an oscillation, in particular a harmonic oscillation. in which at least one of the nested containers is weighed by means of a weighing device , wherein a relative movement between the at least one pharmaceutical container and the carrier is caused in order to release the pharmaceutical container from the carrier to increase the weighing accuracy, characterized in that the relative movement is caused by an oscillation, in particular a harmonic oscillation.
Final drive for a motor vehicle comprising a drive assembly having a drive shaft , wherein the drive shaft is coupled via a gear stage to an output shaft of the final drive , wherein the drive shaft is coupled to the gear stage via an intermediate shaft that is arranged offset with respect to it, and wherein the intermediate shaft lies on a first side of a conceptual plane incorporating an axis of rotation of the drive shaft , characterised in that a power electronics unit is arranged on the drive assembly at the front end thereof on a second side of the plane, which lies opposite to the first side, and is electrically connected to the drive assembly via connection terminals arranged at the front end thereof.
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: R 1 is hydrogen, halogen, -C 1 -C 4 -alkyl, -C 1 -C 4 -haloalkyl, -CN, -C 1 -C 4 -alkoxy, -C 1 -C 4 -haloalkoxy, or -C 3 -C 6 -cycloalkyl; Q 1 is N; R 2 is halogen, -C 1 -C 4 -alkyl, -C 1 -C 4 -haloalkyl, -C 1 -C 4 -haloalkoxy, -S(C 1 -C 4 -alkyl), or furanyl, wherein the furanyl can be optionally substituted with -C 1 -C 4 -alkyl; x is an integer having a value of 1 or 2; each R 20 is independently hydrogen, halogen, -C 1 -C 4 -alkyl, -CN, or -C 1 -C 4 -alkoxy; and R 3 is -CH 3 or -CD 3 . R 1 is hydrogen, halogen, -C 1 -C 4 -alkyl, -C 1 -C 4 -haloalkyl, -CN, -C 1 -C 4 -alkoxy, -C 1 -C 4 -haloalkoxy, or -C 3 -C 6 -cycloalkyl; Q 1 is N; R 2 is halogen, -C 1 -C 4 -alkyl, -C 1 -C 4 -haloalkyl, -C 1 -C 4 -haloalkoxy, -S(C 1 -C 4 -alkyl), or furanyl, wherein the furanyl can be optionally substituted with -C 1 -C 4 -alkyl; x is an integer having a value of 1 or 2; each R 20 is independently hydrogen, halogen, -C 1 -C 4 -alkyl, -CN, or -C 1 -C 4 -alkoxy; and R 3 is -CH 3 or -CD 3 .
Push switch having a contact rocker which is mounted in a base part such that it can pivot about a first pivot axis (S1) and which is designed such that it can be moved back and forth between a first contact position and a second contact position, and having a switching arm which is mounted on the base part about a second pivot axis (S2) and which is designed such that it can be moved from an inoperative position to an operative position by means of an operating force which acts on an operating side of the switching arm , and having a switching rocker which is mounted in the base part such that it can pivot about a third pivot axis (S3) and which is designed such that it can be moved back and forth between a first switching position and a second switching position, wherein the contact rocker can be moved indirectly by way of the switching rocker , depending on the previous position of the contact rocker , from the first contact position to the second contact position, or vice versa, by means of the movement of the switching arm from the inoperative position to the operative position, characterized in that the switching arm , by way of its movement from the inoperative position to the operative position, pivots a derailleur receptacle , which is mounted about a fourth pivot axis (S4), in the base part from a starting position to a functional position, and the fourth pivot axis (S4) of the derailleur receptacle is arranged offset in a mounting direction (M) of the push switch behind the second pivot axis (S2) of the switching arm and laterally offset in a direction perpendicular to the mounting direction (M) in relation to the second pivot axis (S2) of the switching arm , and a derailleur is arranged mounted in the derailleur receptacle such that it can pivot about a fifth pivot axis (S5), and the derailleur , depending on the current switching position of the switching rocker , moves the switching rocker to the respectively other switching position by way of the movement of the derailleur receptacle from the starting position to the functional position.
A connection device for connecting a tubular film to an apparatus, wherein the connection device comprises: a base body , which forms a channel , wherein the channel extends along a channel axis (A) and ends at an opening of the base body and emerges to the exterior; a clamping device , which surrounds the opening of the base body and which is designed to clamp the tubular film, after it has been pulled over the base body , in a clamping space , in such a way that the tubular film is fastened in a sealed manner and a powdered/granulated product can be transferred contamination-free between the base body and the tubular film; and characterised in that an introduction means , which at least partially surrounds the base body and the tubular film pulled over the base body , wherein the introduction means is designed to be displaced radially with respect to the channel axis (A), in such a way that it constricts the tubular film radially and thereby introduces it into the clamping space . a base body , which forms a channel , wherein the channel extends along a channel axis (A) and ends at an opening of the base body and emerges to the exterior; a clamping device , which surrounds the opening of the base body and which is designed to clamp the tubular film, after it has been pulled over the base body , in a clamping space , in such a way that the tubular film is fastened in a sealed manner and a powdered/granulated product can be transferred contamination-free between the base body and the tubular film; and characterised in that an introduction means , which at least partially surrounds the base body and the tubular film pulled over the base body , wherein the introduction means is designed to be displaced radially with respect to the channel axis (A), in such a way that it constricts the tubular film radially and thereby introduces it into the clamping space .
A hybrid container comprising a rigid fibrous outer part and a rigid plastic inner part ; the inner part being configured to contain a product; wherein the inner part is removably attached to the outer part such that at least a portion of the inner part is disposed inside the outer part , wherein the inner part comprises a rigid first plastic part removably connected to a rigid second plastic part , the first plastic part being disposed substantially within the second plastic part and being configured to contain the product; and the second plastic part being removably connected to the fibrous outer part , and wherein the fibrous outer part is made of cardboard. inner part ; the inner part being configured to contain a product; wherein the inner part is removably attached to the outer part such that at least a portion of the inner part is disposed inside the outer part , wherein the inner part comprises a rigid first plastic part removably connected to a rigid second plastic part , the first plastic part being disposed substantially within the second plastic part and being configured to contain the product; and the second plastic part being removably connected to the fibrous outer part , and wherein the fibrous outer part is made of cardboard.
A method for operating an internal combustion engine of a diesel internal combustion engine of a ship operated with heavy fuel oil, wherein the internal combustion engine comprises a combustion engine for the combustion of fuel and an exhaust gas aftertreatment system connected downstream of the combustion engine for cleaning exhaust gas created during the combustion of the fuel using a reducing agent and/or an absorbent, wherein dependent on costs of the fuel to be combusted in the combustion engine and dependent on costs of the reducing agent and/or absorbent to be used in the exhaust gas aftertreatment system for the exhaust gas aftertreatment the internal combustion engine is operated in an operating point, in which minimal operating resources costs of fuel and reducing agent and/or absorbent are incurred, wherein for changing the raw emissions of the internal combustion engine and the implementation behaviour of the exhaust gas aftertreatment device and thus the required reducing agent quantities and/or absorbent quantities characteristic diagrams are utilised, wherein by changing at least one of the following engine parameters: - fuel/air ratio - fuel injection pressure, - fuel injection timing, - injection quantity the raw emissions in the exhaust gas of the combustion engine are automatically adjusted in such a manner that as a consequence of the reducing agent quantity and/or absorbent quantity needed for the exhaust gas aftertreatment in the exhaust gas aftertreatment system minimum operating resources costs of fuel and reducing agent and/or absorbent are incurred, characterized in that upon a failure of the exhaust gas aftertreatment the raw emission of the engine and/or the fuel type are automatically selected so that the respectively applicable limit values are adhered to and that the engine can be operated with different fuels and, during the operation with different fuels, different characteristic diagrams are utilised in each case, in that costs of the fuel and costs of the reducing agent and/or absorbent are updated. - fuel/air ratio - fuel injection pressure, - fuel injection timing, - injection quantity
A connecting apparatus comprising: a first connection for a vacuum device , in particular a vacuum pump or an accessory unit for a vacuum pump; a plurality of second connections for a respective operating apparatus for the vacuum device ; a communication control unit configured to: - receive a first operating message from a first operating apparatus ; - forward the first operating message to the vacuum device; - receive a second operating message from a second operating apparatus after the first operating message was received; characterised in that the communication control unit is further configured to - receive an answer to the first communication operation message from the vacuum device ; and - forward the second operation message to the vacuum device after the answer has been received. a first connection for a vacuum device , in particular a vacuum pump or an accessory unit for a vacuum pump; a plurality of second connections for a respective operating apparatus for the vacuum device ; a communication control unit configured to: - receive a first operating message from a first operating apparatus ; - forward the first operating message to the vacuum device; - receive a second operating message from a second operating apparatus after the first operating message was received; - receive a first operating message from a first operating apparatus ; - forward the first operating message to the vacuum device; - receive a second operating message from a second operating apparatus after the first operating message was received; characterised in that the communication control unit is further configured to - receive an answer to the first communication operation message from the vacuum device ; and - forward the second operation message to the vacuum device after the answer has been received. - receive an answer to the first communication operation message from the vacuum device ; and - forward the second operation message to the vacuum device after the answer has been received.
A beverage preparation machine comprising a source of liquid and a dispensing outlet connected via a pump that has: - a chamber ; - a displaceable wall delimiting the chamber , such as a displaceable wall joined to adjacent chamber wall(s) by a seal , e.g. an O-ring; - an electric actuator driving the displaceable wall between a first position and a second position for causing an inflow of liquid from the source into the chamber and for causing an outflow of liquid from the chamber to the dispensing outlet optionally via a thermal conditioner , such as a heater and/or cooler; and - a powering unit that comprises an electric power source and that is configured for supplying power to the actuator , characterised in that the powering unit further comprises: - a sensor , e.g. at least one of an ammeter, a voltmeter and a potentiometer, for measuring at least one electrical parameter representative of a consumption of power by the actuator from said source ; and - a control unit connected to the sensor and to the electrical power source , the control unit being configured to control the power supplied to the actuator by the electric power source as a function of: - the at least one measured parameter; and - a desired liquid input into the chamber and/or a desired liquid output from the chamber , such as a desired flow and/or pressure of the liquid input and/or of the liquid output. - a chamber ; - a displaceable wall delimiting the chamber , such as a displaceable wall joined to adjacent chamber wall(s) by a seal , e.g. an O-ring; - an electric actuator driving the displaceable wall between a first position and a second position for causing an inflow of liquid from the source into the chamber and for causing an outflow of liquid from the chamber to the dispensing outlet optionally via a thermal conditioner , such as a heater and/or cooler; and - a powering unit that comprises an electric power source and that is configured for supplying power to the actuator , - a sensor , e.g. at least one of an ammeter, a voltmeter and a potentiometer, for measuring at least one electrical parameter representative of a consumption of power by the actuator from said source ; and - a control unit connected to the sensor and to the electrical power source , the control unit being configured to control the power supplied to the actuator by the electric power source as a function of: - the at least one measured parameter; and - a desired liquid input into the chamber and/or a desired liquid output from the chamber , such as a desired flow and/or pressure of the liquid input and/or of the liquid output. - the at least one measured parameter; and - a desired liquid input into the chamber and/or a desired liquid output from the chamber , such as a desired flow and/or pressure of the liquid input and/or of the liquid output.