mhurhangee/patent-ind-claim-en huggingface dataset:
A method of determining a fractional concentration of fetal DNA in a biological sample of a female subject pregnant with a fetus, the biological sample including nucleic acid molecules from the female subject and from the fetus, and wherein the female subject is homozygous at a first locus for a first allele and the fetus is heterozygous at the first locus for the first allele and a second allele different from the first allele, the method comprising: receiving first data from a first plurality of reactions involving nucleic acid molecules from the biological sample, wherein the reactions are indicative of a presence or absence of two polynucleotide sequences of interest, the two polynucleotide sequences of interest being the first allele and the second allele at the first locus, wherein the first plurality of reactions are digital polymerase chain reactions, and wherein the first data includes: a first set of quantitative data indicating a first number of reactions positive for the presence of the first allele; and a second set of quantitative data indicating a second number of reactions positive for the presence of the second allele; and calculating a fraction of the first number to the second number to determine the fractional concentration of fetal DNA. receiving first data from a first plurality of reactions involving nucleic acid molecules from the biological sample, wherein the reactions are indicative of a presence or absence of two polynucleotide sequences of interest, the two polynucleotide sequences of interest being the first allele and the second allele at the first locus, wherein the first plurality of reactions are digital polymerase chain reactions, and wherein the first data includes: a first set of quantitative data indicating a first number of reactions positive for the presence of the first allele; and a second set of quantitative data indicating a second number of reactions positive for the presence of the second allele; and a first set of quantitative data indicating a first number of reactions positive for the presence of the first allele; and a second set of quantitative data indicating a second number of reactions positive for the presence of the second allele; and calculating a fraction of the first number to the second number to determine the fractional concentration of fetal DNA.
Apparatus for curling hair comprising first and second side portions which are secured together in a spaced apart relationship via a connector portion , the connector portion being positioned substantially centrally with respect to each side portion; and wherein the side portions are fabricated from a material which is both resilient and thermally conductive; wherein the first side portion is substantially flat and the second side portion is configured such that it is provided with two fixed states: a first state in which the second side portion is convex in shape and bends away from the second plate; and a second fixed state in which the second side portion is concave in shape and folds over to cover both the connector portion and the first side portion; characterised in that the first side portion is provided with at least one barrier member extending from the first side portion towards the second side portion in substantially the same direction as the connector portion and spaced apart from the connector portion , wherein the at least one barrier member has a height, and the connector portion has a length and the ratio of the height of the barrier member to the length of the connector portion is at least 1:3. wherein the first side portion is substantially flat and the second side portion is configured such that it is provided with two fixed states: a first state in which the second side portion is convex in shape and bends away from the second plate; and a second fixed state in which the second side portion is concave in shape and folds over to cover both the connector portion and the first side portion; characterised in that the first side portion is provided with at least one barrier member extending from the first side portion towards the second side portion in substantially the same direction as the connector portion and spaced apart from the connector portion , wherein the at least one barrier member has a height, and the connector portion has a length and the ratio of the height of the barrier member to the length of the connector portion is at least 1:3.
HPEM source for the emission of an HPEM pulse in a desired radiation direction , - with at least three antennas fitted at a fixed position relative to one another for the respective emission of a pulse component , - wherein at least two of the antennas are combined in each case into a group , and at least two groups of antennas which differ from one another in terms of at least one antenna are present, - wherein one main direction is assigned to each of the groups and at least two different main directions are present, and - wherein, for at least two of the groups , all antennas of the group are arranged along a straight line , wherein the straight line is the respective main direction , wherein at least two of the respective straight lines are different diameter lines of an imaginary circle, wherein the antennas of a respective group are distributed along the straight lines on one radius or on the entire diameter, - with a control unit which is configured to control the antennas in terms of the activation and the phase angle of their respective pulse component in such a way that, for at least one of the groups , at least two antennas of the group are actively controlled, wherein the pulse components of the actively controlled antennas are superimposed on one another to form the HPEM pulse , the current radiation direction of which is in a specific angle range around the respective main direction , wherein the angle range is less than 360°. - with at least three antennas fitted at a fixed position relative to one another for the respective emission of a pulse component , - wherein at least two of the antennas are combined in each case into a group , and at least two groups of antennas which differ from one another in terms of at least one antenna are present, - wherein one main direction is assigned to each of the groups and at least two different main directions are present, and - wherein, for at least two of the groups , all antennas of the group are arranged along a straight line , wherein the straight line is the respective main direction , wherein at least two of the respective straight lines are different diameter lines of an imaginary circle, wherein the antennas of a respective group are distributed along the straight lines on one radius or on the entire diameter, - with a control unit which is configured to control the antennas in terms of the activation and the phase angle of their respective pulse component in such a way that, for at least one of the groups , at least two antennas of the group are actively controlled, wherein the pulse components of the actively controlled antennas are superimposed on one another to form the HPEM pulse , the current radiation direction of which is in a specific angle range around the respective main direction , wherein the angle range is less than 360°.
Building having several exterior walls (2; 3, 4), wherein the exterior walls (2; 3, 4) are formed by a sidewall or roof of the building , and an insulation system against at least one exterior wall (2; 3, 4), wherein the insulation system comprises several rectangular insulation cassettes (30a-30h), wherein the insulation cassettes (30a-30h) comprise a plastic tray and a separate plastic cover , wherein the tray has a bottom wall and a circumferential wall upright therefrom that are integrally formed and the cover closes off the open side of the tray , wherein the tray and the cover are provided with cooperating attachment members for attachment of the cover onto the tray , wherein the bottom wall is situated on the side of the exterior wall (2; 3, 4) and the cover is placed on the upper side of the tray which side faces away from the exterior wall (2; 3, 4), characterized in that on the upper side of the circumferential wall which side faces away from the bottom wall the tray is provided with an insert frame , wherein the insert frames of consecutive trays engage onto each other.
Use of a replication deficient recombinant Sindbis virus comprising an RNA genome comprising: an open reading frame (ORF) encoding functional Sindbis non-structural proteins; and a heterologous RNA sequence, wherein the heterologous RNA sequence comprises at least 50 bp of an enveloped non-Sindbis RNA virus sequence or a retrovirus sequence; as a control in a nucleic acid diagnostic assay for the detection of an enveloped non-Sindbis RNA-containing virus or a retrovirus. an open reading frame (ORF) encoding functional Sindbis non-structural proteins; and a heterologous RNA sequence, wherein the heterologous RNA sequence comprises at least 50 bp of an enveloped non-Sindbis RNA virus sequence or a retrovirus sequence;
System for connecting two drill string members of a drill string for earth drilling, wherein one drill string member has a plug element arranged on an end side in the form of a plug and the other drill string member has a plug element arranged on an end side in the form of a socket and a removal prevention device is provided, which has a head and an end spaced apart from the head, characterized in that a thread is formed on the end of the removal prevention device , wherein the plug and socket are designed to form a plug-in connection in such a way that both drill string members have through-holes aligned with one another, through which the removal prevention device can be inserted, and the head and end are spaced apart from one another such that the head is exposed at the end with the removal prevention device inserted.
A workpiece takeout system comprising: a robot arm configured to perform a workpiece takeout operation to take out a workpiece disposed in an area among a plurality of areas; and a disposed-state detector configured to collectively pick up an image of said plurality of areas and to detect a disposed state of the workpiece and configured to, while the robot arm is performing the workpiece takeout operation to take out the workpiece disposed in the area among the plurality of areas, detect a disposed state of another workpiece disposed in another area among the plurality of areas. a robot arm configured to perform a workpiece takeout operation to take out a workpiece disposed in an area among a plurality of areas; and a disposed-state detector configured to collectively pick up an image of said plurality of areas and to detect a disposed state of the workpiece and configured to, while the robot arm is performing the workpiece takeout operation to take out the workpiece disposed in the area among the plurality of areas, detect a disposed state of another workpiece disposed in another area among the plurality of areas.
A sheet stacking apparatus comprising: a shelf unit in which a printed sheet from a printer is received and stacked, a lifting and lowering mechanism that lifts and lowers the shelf unit , and a control unit that controls the lifting and lowering mechanism , the control unit controlling the lifting and lowering mechanism to lift and lower the shelf unit to a first predetermined height corresponding to the printer at a receiving position (PS1) for receiving the sheet from the printer, and to lift and lower the shelf unit to a second predetermined height corresponding to a sheet processing machine at a supply position (PS2) for supplying the sheet to the sheet processing machine, the supply position (PS2) being different from the receiving position (PS1) characterized in that the sheet stacking apparatus further comprises: a tilting mechanism that tilts the shelf unit with respect to a horizontal plane, and an abutment member that abuts on an end portion of the sheet stacked in the shelf unit , wherein the control unit controls the tilting mechanism to tilt the shelf unit so that an end portion side of the sheet that is not provided with the abutment member is above the other end portion during running from the receiving position (PS1) to the supply position (PS2) a shelf unit in which a printed sheet from a printer is received and stacked, a lifting and lowering mechanism that lifts and lowers the shelf unit , and a control unit that controls the lifting and lowering mechanism , the control unit controlling the lifting and lowering mechanism to lift and lower the shelf unit to a first predetermined height corresponding to the printer at a receiving position (PS1) for receiving the sheet from the printer, and to lift and lower the shelf unit to a second predetermined height corresponding to a sheet processing machine at a supply position (PS2) for supplying the sheet to the sheet processing machine, the supply position (PS2) being different from the receiving position (PS1) characterized in that the sheet stacking apparatus further comprises: a tilting mechanism that tilts the shelf unit with respect to a horizontal plane, and an abutment member that abuts on an end portion of the sheet stacked in the shelf unit , wherein the control unit controls the tilting mechanism to tilt the shelf unit so that an end portion side of the sheet that is not provided with the abutment member is above the other end portion during running from the receiving position (PS1) to the supply position (PS2) a tilting mechanism that tilts the shelf unit with respect to a horizontal plane, and an abutment member that abuts on an end portion of the sheet stacked in the shelf unit , wherein the control unit controls the tilting mechanism to tilt the shelf unit so that an end portion side of the sheet that is not provided with the abutment member is above the other end portion during running from the receiving position (PS1) to the supply position (PS2)
Arrangement comprising a rotatable means, a sensor, and an evaluation unit; the means having a number a of markings; the markings cyclically passing through a region detected by the sensor while the means is in rotation; the sensor being designed to transmit a signal to the evaluation unit; and the evaluation unit being designed to assign to each signal a time t i of its transmission, where i ∈ {0, 1, ... } and t i < t i +1 for all i ∈ {0, 1, ... }, and to calculate a function n(t) dependent on time t as a measure for a rotational speed of the means, where n t i = 1 a ⋅ t i − t i − 1 for all i ∈ {1, 2, ... }; the evaluation unit being designed to calculate a function m(t) dependent on time t as a measure for a gradient of the rotational speed of the means, where m t j = n t j − n t k t j − t k for at least one j ∈ {1,2, ... }; with k ∈ {0, 1, ... } being chosen such that the following applies: t k ≤ t j - T < t k +1' with a constant T; with moreover the following applying: m t j , = n t j , − n min t j , − t k , for at least one j ' ∈ {1,2, ... }; with n ( t k' ) < n min applying and k' ∈ {0,1, ... } being chosen such that the following applies: t k' ≤ t j' - T < t k' +1 . the means having a number a of markings; the markings cyclically passing through a region detected by the sensor while the means is in rotation; the sensor being designed to transmit a signal to the evaluation unit; and the evaluation unit being designed to assign to each signal a time t i of its transmission, where i ∈ {0, 1, ... } and t i < t i +1 for all i ∈ {0, 1, ... }, and to calculate a function n(t) dependent on time t as a measure for a rotational speed of the means, where n t i = 1 a ⋅ t i − t i − 1 for all i ∈ {1, 2, ... }; the evaluation unit being designed to calculate a function m(t) dependent on time t as a measure for a gradient of the rotational speed of the means, where m t j = n t j − n t k t j − t k for at least one j ∈ {1,2, ... }; with k ∈ {0, 1, ... } being chosen such that the following applies: t k ≤ t j - T < t k +1' with a constant T; with moreover the following applying: m t j , = n t j , − n min t j , − t k , for at least one j ' ∈ {1,2, ... }; with n ( t k' ) < n min applying and k' ∈ {0,1, ... } being chosen such that the following applies: t k' ≤ t j' - T < t k' +1 .
Method to heat exhaust gases to a selected specific temperature by fuel injection control in an internal combustion engine operated in a four stroke cycle, which ICE comprises a control unit registering the currently requested load and determining a required fuel amount in response to the requested load, performing the steps of: - registering low load operation of the internal combustion engine ; - registering an input from at least one exhaust after-treatment system sensor indicating a detected condition; - determining an exhaust temperature requirement for the detected condition and calculating a target exhaust temperature; - selecting a group of cylinders to be regulated for achieving the target exhaust temperature; - calculating a ratio for desired 1 st and 2 nd fuel amounts to be injected alternately in consecutive induction strokes for the selected group of cylinders to achieve the target exhaust temperature; wherein the ratio defines an offset between an increased 1 st fuel amount to be injected in a cylinder of the selected group of cylinders for every second induction stroke, and a reduced 2 nd fuel amount to be injected for the intermediate induction strokes, characterized by monitoring the exhaust temperature and adjusting the number of selected cylinders to be regulated for achieving the target exhaust temperature. performing the steps of: - registering low load operation of the internal combustion engine ; - registering an input from at least one exhaust after-treatment system sensor indicating a detected condition; - determining an exhaust temperature requirement for the detected condition and calculating a target exhaust temperature; - selecting a group of cylinders to be regulated for achieving the target exhaust temperature; - calculating a ratio for desired 1 st and 2 nd fuel amounts to be injected alternately in consecutive induction strokes for the selected group of cylinders to achieve the target exhaust temperature; - registering low load operation of the internal combustion engine ; - registering an input from at least one exhaust after-treatment system sensor indicating a detected condition; - determining an exhaust temperature requirement for the detected condition and calculating a target exhaust temperature; - selecting a group of cylinders to be regulated for achieving the target exhaust temperature; - calculating a ratio for desired 1 st and 2 nd fuel amounts to be injected alternately in consecutive induction strokes for the selected group of cylinders to achieve the target exhaust temperature; wherein the ratio defines an offset between an increased 1 st fuel amount to be injected in a cylinder of the selected group of cylinders for every second induction stroke, and a reduced 2 nd fuel amount to be injected for the intermediate induction strokes, characterized by monitoring the exhaust temperature and adjusting the number of selected cylinders to be regulated for achieving the target exhaust temperature.
An analysis method comprising: a sample preparation step of preparing a measurement sample by mixing a measurement object containing pyrroloquinoline quinone or a salt thereof with glycine so that the pyrroloquinoline quinone or the salt thereof reacts with the glycine to produce imidazopyrroloquinoline or a salt thereof; and characterised by a quantitative analysis step of determining quantitatively an amount of the pyrroloquinoline quinone or the salt thereof contained in the measurement object, based on a chromatogram of the imidazopyrroloquinoline or the salt thereof contained in the measurement sample obtained by chromatography. a sample preparation step of preparing a measurement sample by mixing a measurement object containing pyrroloquinoline quinone or a salt thereof with glycine so that the pyrroloquinoline quinone or the salt thereof reacts with the glycine to produce imidazopyrroloquinoline or a salt thereof; and characterised by a quantitative analysis step of determining quantitatively an amount of the pyrroloquinoline quinone or the salt thereof contained in the measurement object, based on a chromatogram of the imidazopyrroloquinoline or the salt thereof contained in the measurement sample obtained by chromatography.
An active noise reducing headphone comprising: a rigid cup-like shell having an inner surface and an outer surface ; the inner surface encompassing a cavity with an opening ; a microphone arrangement configured to pick up sound at least at three positions that are regularly distributed over the outer surface , and to provide a first electrical signal that represents the picked-up sound; an active noise control filter configured to provide, based on the first electrical signal, a second electrical signal; and a speaker disposed in the opening of the cavity and configured to generate sound from the second electrical signal; where the active noise control filter has a transfer characteristic that is configured so that noise that travels through the shell from beyond the outer surface to beyond the inner surface is reduced by the sound generated by the speaker , characterised in that the microphone arrangement comprises a microphone with an extended membrane area, the microphone configured to pick up sound over more than 50% of the surface area of the outer surface . a rigid cup-like shell having an inner surface and an outer surface ; the inner surface encompassing a cavity with an opening ; a microphone arrangement configured to pick up sound at least at three positions that are regularly distributed over the outer surface , and to provide a first electrical signal that represents the picked-up sound; an active noise control filter configured to provide, based on the first electrical signal, a second electrical signal; and a speaker disposed in the opening of the cavity and configured to generate sound from the second electrical signal; where the active noise control filter has a transfer characteristic that is configured so that noise that travels through the shell from beyond the outer surface to beyond the inner surface is reduced by the sound generated by the speaker , characterised in that the microphone arrangement comprises a microphone with an extended membrane area, the microphone configured to pick up sound over more than 50% of the surface area of the outer surface .
Transformer comprising two coils , wherein each coil has a core and a plurality of windings, and wherein the coils are held in a carrier device , wherein the carrier device has feet for positioning the carrier device on a support , characterized in that the carrier device has two feet that are spaced apart from one another, wherein a pressing beam protrudes from each foot and wherein the coils extend between the pressing beams and the longitudinal axes of the coils are able to be oriented so as to be horizontal by positioning the carrier device on the support and in that the coils are arranged above one another.