mhurhangee/patent-ind-claim-en huggingface dataset:
A method for detecting the presence of DNA mutations in the KRAS, BRAF, CTNNB1, and APC genes, the method comprising: (a) isolating DNA from a sample; (b) amplifying the isolated DNA by polymerase chain reaction (PCR) using primer pairs specific for the loci of one or more DNA mutations in each of the KRAS, BRAF, CTNNB1, and APC genes, wherein the isolated DNA is amplified in the presence of at least four blocking nucleic acids, wherein each of said at least four blocking nucleic acids hybridizes with a wild-type DNA locus corresponding with one of the DNA mutations in the KRAS, BRAF, CTNNB1, or APC genes and prevents amplification of the wild-type DNA locus, wherein optionally the KRAS, BRAF, CTNNB1, and APC genes are human genes; (c) hybridizing the amplified DNA with at least four probes, said at least four probes comprising one or more probes specific for a DNA mutation in each of the KRAS, BRAF, CTNNB1, and APC genes, wherein each of said at least four probes is coupled to a microcarrier, and wherein each of the microcarriers comprises an identifier corresponding to the probe coupled thereto; (d) detecting presence or absence of hybridization of the amplified DNA with said at least four probes, wherein hybridization between the amplified DNA and one of the probes indicates the presence of the DNA mutation corresponding to the probe; (e) detecting the identifiers of the microcarriers; and (f) correlating the detected identifiers of the microcarriers with the detected presence or absence of hybridization of the amplified DNA to the corresponding probes of the microcarriers. (a) isolating DNA from a sample; (b) amplifying the isolated DNA by polymerase chain reaction (PCR) using primer pairs specific for the loci of one or more DNA mutations in each of the KRAS, BRAF, CTNNB1, and APC genes, wherein the isolated DNA is amplified in the presence of at least four blocking nucleic acids, wherein each of said at least four blocking nucleic acids hybridizes with a wild-type DNA locus corresponding with one of the DNA mutations in the KRAS, BRAF, CTNNB1, or APC genes and prevents amplification of the wild-type DNA locus, wherein optionally the KRAS, BRAF, CTNNB1, and APC genes are human genes; (c) hybridizing the amplified DNA with at least four probes, said at least four probes comprising one or more probes specific for a DNA mutation in each of the KRAS, BRAF, CTNNB1, and APC genes, wherein each of said at least four probes is coupled to a microcarrier, and wherein each of the microcarriers comprises an identifier corresponding to the probe coupled thereto; (d) detecting presence or absence of hybridization of the amplified DNA with said at least four probes, wherein hybridization between the amplified DNA and one of the probes indicates the presence of the DNA mutation corresponding to the probe; (e) detecting the identifiers of the microcarriers; and (f) correlating the detected identifiers of the microcarriers with the detected presence or absence of hybridization of the amplified DNA to the corresponding probes of the microcarriers.
A vehicle air-conditioning method for a vehicle comprising an ignition device provided in the vehicle cabin and an air-conditioning device having an all-seat air-conditioning mode in which air-conditioned air is blown out to occupants of all of seats in the vehicle cabin and an individual air-conditioning mode in which the air-conditioned air is blown out to some of the occupants of all of the seats, the method comprising: storing the air-conditioning mode of the air-conditioning device selected at the turning-off of the ignition device , characterized in that the method further comprises the following steps: when the vehicle is activated by turning-on the ignition device , controlling the air-conditioning device so that the air-conditioning mode is set to the air-conditioning mode selected at the previous turning-off of the ignition device ; and when a vehicle is activated by a remote starter device configured to remotely activate the vehicle, controlling the air-conditioning device by switching the air-conditioning mode to the all-seat air-conditioning mode even when the air-conditioning mode selected at the previous turning-off of an ignition device is the individual air-conditioning mode, so as to make the temperature inside the entire vehicle cabin uniform. when the vehicle is activated by turning-on the ignition device , controlling the air-conditioning device so that the air-conditioning mode is set to the air-conditioning mode selected at the previous turning-off of the ignition device ; and when a vehicle is activated by a remote starter device configured to remotely activate the vehicle, controlling the air-conditioning device by switching the air-conditioning mode to the all-seat air-conditioning mode even when the air-conditioning mode selected at the previous turning-off of an ignition device is the individual air-conditioning mode, so as to make the temperature inside the entire vehicle cabin uniform.
A molding made of foam, wherein at least one fiber (F) is with a fiber region (FB2) located inside the molding and surrounded by the foam while a fiber region (FB1) of the fiber (F) projects from a first side of the molding and a fiber region (FB3) of the fiber (F) projects from a second side of the molding, wherein the foam has been produced by polymerization of a reactive mixture (rM) which comprises the following components (A) to (C): (A) at least one compound having isocyanate-reactive groups, wherein at least one compound having isocyanate-reactive groups has a weight-average molecular weight of at least 1700 g/mol, (B) at least one blowing agent and (C) at least one polyisocyanate which comprises 14% to 100% by weight based on the total weight of the at least one polyisocyanate of at least one polyisocyanate prepolymer, wherein the reactive mixture (rM) comprises no further polyisocyanate other than component (C), wherein the component (A) is produced from a compound selected from the group consisting of alcohols, saccharides, sugar alcohols and amines and the component (B) of the reactive mixture (rM) is selected from the group consisting of n-pentane, isopentane, cyclopentane, 1,1,1,3,3-pentafluorobutane, 1,1,1,3,3-pentafluoropropane, 1,1,1,2,3,3,3-heptafluoropropane, water and hydrofluoroolefins and the component (C) has an isocyanate index in the range from 90 to 180. (A) at least one compound having isocyanate-reactive groups, wherein at least one compound having isocyanate-reactive groups has a weight-average molecular weight of at least 1700 g/mol, (B) at least one blowing agent and (C) at least one polyisocyanate which comprises 14% to 100% by weight based on the total weight of the at least one polyisocyanate of at least one polyisocyanate prepolymer,
A smoke detection system for an enclosed area, the system comprising: a housing having an inlet and an outlet ; a divider within the housing , wherein the housing includes a first compartment to receive air flow from the inlet , and a turning portion configured to direct flow to a second compartment in communication with the outlet ; and a sensor configured to detect smoke in an air flow, said sensor provided within the first compartment ; and characterized in that the divider is a circuit board electrically controlling the sensor . a housing having an inlet and an outlet ; a divider within the housing , wherein the housing includes a first compartment to receive air flow from the inlet , and a turning portion configured to direct flow to a second compartment in communication with the outlet ; and a sensor configured to detect smoke in an air flow, said sensor provided within the first compartment ; and characterized in that the divider is a circuit board electrically controlling the sensor .
A subsonic blast media fragmenter (10; 10a, 10b) comprising a. a body (20; 58a,58b) defining an internal flow path (22; 56) configured to maintain a fluid flow with entrained cryogenic blast media particle at subsonic speed throughout the length of the internal flow path, said internal flow path comprising: i. an inlet (22a; 38; 38a); ii. a converging section (26; 36) disposed downstream of said inlet; and iii. an outlet disposed downstream of said converging section; and b. at least one fragmenting element (24; 60a, 60b) disposed intermediate said converging section and said outlet. a. a body (20; 58a,58b) defining an internal flow path (22; 56) configured to maintain a fluid flow with entrained cryogenic blast media particle at subsonic speed throughout the length of the internal flow path, said internal flow path comprising: i. an inlet (22a; 38; 38a); ii. a converging section (26; 36) disposed downstream of said inlet; and iii. an outlet disposed downstream of said converging section; and i. an inlet (22a; 38; 38a); ii. a converging section (26; 36) disposed downstream of said inlet; and iii. an outlet disposed downstream of said converging section; and b. at least one fragmenting element (24; 60a, 60b) disposed intermediate said converging section and said outlet.
A polyurethane prepared by the reaction product of: a) an NCO-terminated polymer formed from the reaction of a hydroxylated oleaginous component derived from plant oil comprising hydroxylated soybean oil and a diisocyante; and b) an alkoxy-functionalized monomer. a) an NCO-terminated polymer formed from the reaction of a hydroxylated oleaginous component derived from plant oil comprising hydroxylated soybean oil and a diisocyante; and b) an alkoxy-functionalized monomer.
A method for acquiring data for detecting damage to a bearing, comprising the following steps: (a) obtaining (S10) a vibration signal from the bearing over a period of time; (b) determining (S14) spectrograms of said vibration signal at various instants of the period of time; (c) detecting (S22) the peaks on each spectrogram; (d) from among the detected peaks, retaining (S24) the peaks which, in spectrograms corresponding to successive instants and transformed through synchronous resampling at a rotational speed of the bearing, would be present at the same frequency, with a predetermined tolerance; (e) identifying (S26) spectral lines corresponding to the retained peaks; (f) storing (S44) an information item representative of said spectral lines in a record able to be used by a unit for detecting damage to the bearing. (a) obtaining (S10) a vibration signal from the bearing over a period of time; (b) determining (S14) spectrograms of said vibration signal at various instants of the period of time; (c) detecting (S22) the peaks on each spectrogram; (d) from among the detected peaks, retaining (S24) the peaks which, in spectrograms corresponding to successive instants and transformed through synchronous resampling at a rotational speed of the bearing, would be present at the same frequency, with a predetermined tolerance; (e) identifying (S26) spectral lines corresponding to the retained peaks; (f) storing (S44) an information item representative of said spectral lines in a record able to be used by a unit for detecting damage to the bearing.
A neutron capture therapy system comprising: an accelerator for accelerating a charged particle beam (P); a charged particle beam inlet allowing the charged particle beam to pass through; a neutron beam generating unit (T) generating a neutron beam (N) after a nuclear reaction occurs between the neutron beam generating unit and the charged particle beam; a beam shaping assembly for adjusting the flux and the quality of the neutron beam generated by the neutron beam generating unit; and a beam outlet adjacent to the beam shaping assembly; characterized in that the neutron capture therapy system is configured to correct a non-linear relationship between boron concentration and tumor dose; wherein the neutron capture therapy system comprises a radiation detection system, and the radiation detection system comprises a radiation detection device for real-time detection of γ rays instantly emitted under neutron beam irradiation; and the radiation detection system is configured to calculate a boron concentration value through a detected γ signal and the neutron capture therapy system is configured to calculate a tumor dose through the boron concentration value, wherein the neutron capture therapy system is configured to correct the non-linear relationship between boron concentration and tumor dose when calculating the tumor dose. an accelerator for accelerating a charged particle beam (P); a charged particle beam inlet allowing the charged particle beam to pass through; a neutron beam generating unit (T) generating a neutron beam (N) after a nuclear reaction occurs between the neutron beam generating unit and the charged particle beam; a beam shaping assembly for adjusting the flux and the quality of the neutron beam generated by the neutron beam generating unit; and a beam outlet adjacent to the beam shaping assembly; characterized in that the neutron capture therapy system is configured to correct a non-linear relationship between boron concentration and tumor dose; wherein the neutron capture therapy system comprises a radiation detection system, and the radiation detection system comprises a radiation detection device for real-time detection of γ rays instantly emitted under neutron beam irradiation; and the radiation detection system is configured to calculate a boron concentration value through a detected γ signal and the neutron capture therapy system is configured to calculate a tumor dose through the boron concentration value, wherein the neutron capture therapy system is configured to correct the non-linear relationship between boron concentration and tumor dose when calculating the tumor dose.
A down-hole tool for use inside a well comprising: - a housing ; - an anchoring arm rotatably attached to the housing and configured to move between an open position and a closed position; - a spring block configured to have a central part that moves along a longitudinal axis (X) of the housing which results in the movement of the anchoring arm between the open or closed positions, said spring block comprising a spring in contact with central part and configured to bias central part toward one end of the spring block so that the anchoring arm can open or close under the pressure exerted by the spring ; and - an actuating mechanism connected to the central part and configured to move the central part along the longitudinal axis, wherein the spring block is attached to the housing and detachable from the housing , and wherein the spring block is configured, when located inside the housing with a first orientation, to bias the anchoring arm to close, and, when located with a second orientation, opposite to the first orientation, to bias the anchoring arm to open. - a housing ; - an anchoring arm rotatably attached to the housing and configured to move between an open position and a closed position; - a spring block configured to have a central part that moves along a longitudinal axis (X) of the housing which results in the movement of the anchoring arm between the open or closed positions, said spring block comprising a spring in contact with central part and configured to bias central part toward one end of the spring block so that the anchoring arm can open or close under the pressure exerted by the spring ; and - a spring block configured to have a central part that moves along a longitudinal axis (X) of the housing which results in the movement of the anchoring arm between the open or closed positions, said spring block comprising a spring in contact with central part and configured to bias central part toward one end of the spring block so that the anchoring arm can open or close under the pressure exerted by the spring ; and - an actuating mechanism connected to the central part and configured to move the central part along the longitudinal axis,
A print head for additive manufacturing, comprising a heating chamber for melting an additive manufacturing ink in the form of a filament, said heating chamber including - a nozzle for extruding molten material, and - a filament inlet for being connected to a filament supply line ; said print head further comprising a cover outside the heating chamber and movable relative to heating chamber between - a first position in which the nozzle is covered by the cover , and - a second position in which the cover is distant from the nozzle such that the nozzle is not covered by the cover , characterized in that , said cover includes a flexible surface to partly deform at contacting with the nozzle when in the first position and said surface includes a flexible polymeric material. - a nozzle for extruding molten material, and - a filament inlet for being connected to a filament supply line ; said print head further comprising a cover outside the heating chamber and movable relative to heating chamber between - a first position in which the nozzle is covered by the cover , and - a second position in which the cover is distant from the nozzle such that the nozzle is not covered by the cover ,
A circuit carrier for positioning a circuit (D) that measures parameters of the cardan shaft and that is arranged to be connected to a rotating part of the cardan shaft that is connected with the vehicle chassis with a center bearing connection that holds a center bearing containing a fixed coil carrier for holding a winding (S) arranged on the center bearing side, the circuit carrier having a carrier body having an opening arranged to allow the rotating part of the cardan shaft to pass through and is provided such that it engages the rotating part of the cardan shaft; and a circuit assembly surface provided on said carrier body as a radially extending surface; being characterised in that it further comprises at least one elevation foot provided as an axially extending projection on said circuit assembly surface ; a circuit member (D) provided on the elevation foot such that it does not contact the circuit assembly surface ; at least one channel provided on the circuit assembly surface ; at least one retaining hole provided on the circuit assembly surface ; a coating (K) provided to completely encapsulate said circuit element (D) and at least partially fill the channel and completely fill the retaining hole . a carrier body having an opening arranged to allow the rotating part of the cardan shaft to pass through and is provided such that it engages the rotating part of the cardan shaft; and a circuit assembly surface provided on said carrier body as a radially extending surface; being characterised in that it further comprises at least one elevation foot provided as an axially extending projection on said circuit assembly surface ; a circuit member (D) provided on the elevation foot such that it does not contact the circuit assembly surface ; at least one channel provided on the circuit assembly surface ; at least one retaining hole provided on the circuit assembly surface ; a coating (K) provided to completely encapsulate said circuit element (D) and at least partially fill the channel and completely fill the retaining hole .
A method of reporting, by a user equipment, UE, channel state information, CSI, in a wireless communication system, the method comprising: receiving (S1710), by the UE and from a base station, BS, downlink control information, DCI, related to an aperiodic CSI report that is to be performed by the UE in a slot n; determining, by the UE , a value n CQI_ref based on a number of symbols Z ' related to a time for computing the CSI; determining (S1720), by the UE , a CSI reference resource as being a slot n - n CQI_ref in a time domain that is to be used for generating the aperiodic CSI report; and transmitting (S1730), by the UE and to the BS , the aperiodic CSI report in the slot n, based on the CSI reference resource being slot n - n CQI_ref , characterized in that the n CQI_ref is the smallest value greater than or equal to for which the slot ⌊ Z ′ N symb slot ⌋ n - n CQI_ref satisfies a valid downlink slot criteria, and wherein └·┘ is the floor function and N symb slot is a number of symbols in one slot. receiving (S1710), by the UE and from a base station, BS, downlink control information, DCI, related to an aperiodic CSI report that is to be performed by the UE in a slot n; determining, by the UE , a value n CQI_ref based on a number of symbols Z ' related to a time for computing the CSI; determining (S1720), by the UE , a CSI reference resource as being a slot n - n CQI_ref in a time domain that is to be used for generating the aperiodic CSI report; and transmitting (S1730), by the UE and to the BS , the aperiodic CSI report in the slot n, based on the CSI reference resource being slot n - n CQI_ref , characterized in that the n CQI_ref is the smallest value greater than or equal to for which the slot ⌊ Z ′ N symb slot ⌋ n - n CQI_ref satisfies a valid downlink slot criteria, and wherein └·┘ is the floor function and N symb slot is a number of symbols in one slot.
Elastomer toothed belt which has a body which has a length, sides arranged at a lateral distance to one another and an inside and an outside and a multiplicity of teeth arranged spaced apart from one another in a longitudinal direction on the inside or the outside of the body and a fabric which spans the teeth, wherein the elastomer mixture from which the teeth are formed contains a crosslinked ethylene-propylene rubber (EPM) and/or a crosslinked ethylene-propylene terpolymer rubber (EPDM) which accounts for at least 70% by weight, of the elastomer mixture based on the polymer proportion and wherein an interlayer is arranged between the fabric and the elastomer mixture forming the teeth, characterized in that the interlayer contains at least 70% by weight of hydrogenated acrylonitrile-butadiene rubber (HNBR) based on the polymer proportion of the interlayer.
A method for reducing the content of one or more smoke toxicants in a tobacco material, comprising contacting an unharvested mature live tobacco plant or portion thereof with an enzyme to form a treated tobacco plant or portion thereof, wherein the enzyme is asparaginase, and wherein the content of asparagine relative to untreated tobacco material is reduced .
Laminated glazing comprising two sheets of glass and at least one polymer interlayer film and a further polymer interlayer film between the two sheets of glass characterized in that a functional layer comprising light scattering particles is applied to at least one surface of the polymer interlayer film , wherein the polymer interlayer film comprises polyvinyl butyral and optionally a plasticizer W, wherein the content of plasticizer W in the polymer interlayer film before lamination is equal to or less than 5% and wherein the polymer interlayer film has a thickness of equal to or more than 10 μm to equal to or less than 250 μm before lamination and wherein the further polymer interlayer film comprises polyvinyl butyral and before lamination, at least 22 % by weight of a plasticiser.