mhurhangee/patent-ind-claim-en huggingface dataset:
A tunneling tool for creating a pathway for implanting a therapy delivery element in a living body, the tunneling tool comprising: a malleable elongated shaft having a distal end ; a sheath having a lumen slidably positioned over a portion of the shaft ; a primary handle secured to proximal end of the shaft that permits a user to advance and manipulate the shaft and the sheath in the living body; and a secondary handle ; characterized in that the secondary handle is separate and different from the sheath , and has an opening slidably positioned on the shaft between the primary handle and the sheath , the opening having a diameter less than an outside diameter of a proximal end of the sheath so that the secondary handle abuts, but is not attached to, the sheath . a malleable elongated shaft having a distal end ; a sheath having a lumen slidably positioned over a portion of the shaft ; a primary handle secured to proximal end of the shaft that permits a user to advance and manipulate the shaft and the sheath in the living body; and a secondary handle ; characterized in that the secondary handle is separate and different from the sheath , and has an opening slidably positioned on the shaft between the primary handle and the sheath , the opening having a diameter less than an outside diameter of a proximal end of the sheath so that the secondary handle abuts, but is not attached to, the sheath .
Vehicle door handle assembly comprising: - a bowl configured to be mounted in use in an opening of a door panel , characterized in that the vehicle door handle assembly also comprises: - a strip configured to be fastened to an upper part of the bowl , wherein the strip comprises two pins configured to extend through holes made in the bowl and to protrude in two respective apertures of the door panel to ensure the positioning of the strip with respect to the door panel in the vertical direction when the door handle is assembled to the vehicle. - a bowl configured to be mounted in use in an opening of a door panel , characterized in that the vehicle door handle assembly also comprises: - a strip configured to be fastened to an upper part of the bowl ,
A therapeutic nanoparticle comprising: a substantially hydrophobic acid; a therapeutic agent, wherein the pKa of the protonated therapeutic agent is at least about 1.0 pKa units greater than the pKa of the hydrophobic acid, and wherein the therapeutic agent is 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea or pharmaceutically acceptable salt thereof; and a polymer selected from diblock poly(lactic) acid-poly(ethylene)glycol copolymer or a diblock poly(lactic acid-co-glycolic acid)-poly(ethylene)glycol copolymer and combination thereof; for use as a medicament. a substantially hydrophobic acid; a therapeutic agent, wherein the pKa of the protonated therapeutic agent is at least about 1.0 pKa units greater than the pKa of the hydrophobic acid, and wherein the therapeutic agent is 1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea or pharmaceutically acceptable salt thereof; and a polymer selected from diblock poly(lactic) acid-poly(ethylene)glycol copolymer or a diblock poly(lactic acid-co-glycolic acid)-poly(ethylene)glycol copolymer and combination thereof; for use as a medicament.
Cosmetic use, as an agent for treating perspiration, of at least one compound comprising at least one free carbonyl function that is capable of reacting with at least one amine compound via the Maillard reaction, said at least one compound comprising at least one free carbonyl function being a carbohydrate and/or a precursor thereof and/or an oxidized form thereof, and in which the carbohydrate is dihydroxyacetone (DHA) in free form and/or in encapsulated form.
System comprising at least one rail fastening system (S) for fastening a rail element to a ballastless track and a ballastless track , in which an intermediate structure is arranged between a rail element and the ballastless track , by means of which structure the rail element is elastically connected to the ballastless track , characterized in that the intermediate structure merely comprises a single elastic interlayer element (1; 101), which has a variable elasticity distribution over its cross section in the direction of its longitudinal extension and/or in the direction transverse to its longitudinal extension , wherein the single elastic interlayer element (1; 101) has a more elastic inner area of elasticity arranged concentrically around a centre point , and the ballastless track comprises polyvalent sleeper elements, wherein the intermediate structure of the rail fastening system (S) comprises a hard trapezoidal interlayer element (40; 140; 240; 340) with a trapezoidal section (41; 141; 241; 341), which is arranged between the single elastic interlayer element (1; 101) and a component of the ballastless track .
A glazing assembly comprising: a glazing support system, a glazing unit and a frame element (9; 26, 27, 28; 58), wherein the glazing support system is for attaching the glazing unit to the frame element, the glazing support system comprising: a tension member (10; 61) for extending around a major portion of the periphery of the glazing unit; and a connection system (11; 29, 30; 65) for coupling the tension member to the frame element in at least two locations and for transferring tension forces from the tension member to the frame element whilst compression forces arising due to tension in the tension member are applied to the outside of the glazing unit, wherein the frame element includes hinges allowing for the glazing unit to be moved between open and closed positions, and the hinges are joined to connectors (11; 29, 30; 33, 34) and/or tensioning mechanisms (15; 16; 31, 32, 66, 76) for coupling to the tension member; and wherein the tension member is arranged to bear on one or more corners of the glazing unit and to thereby apply a compression force to the glazing unit.
Conjugate comprising an antibody, defined as an immunoglobulin (Ig) or a functional binding fragment or binding domain thereof; at least one saponin that is covalently bound to the antibody, and at least one effector moiety comprising or consisting of any one or more of an oligonucleotide, a nucleic acid and a xeno nucleic acid, wherein the at least one effector moiety is covalently bound to the antibody, either via at least one linker or directly; and wherein the at least one saponin is a triterpenoid saponin and/or a bisdesmosidic triterpene saponin belonging to the type of a 12,13-dehydrooleanane with an aldehyde function in position C-23 and comprising a glucuronic acid function in a carbohydrate substituent at the C-3beta-OH group of the saponin. an antibody, defined as an immunoglobulin (Ig) or a functional binding fragment or binding domain thereof; at least one saponin that is covalently bound to the antibody, and at least one effector moiety comprising or consisting of any one or more of an oligonucleotide, a nucleic acid and a xeno nucleic acid, wherein the at least one effector moiety is covalently bound to the antibody, either via at least one linker or directly; and wherein the at least one saponin is a triterpenoid saponin and/or a bisdesmosidic triterpene saponin belonging to the type of a 12,13-dehydrooleanane with an aldehyde function in position C-23 and comprising a glucuronic acid function in a carbohydrate substituent at the C-3beta-OH group of the saponin.
A backplane connector , comprising: a shroud ; a plurality of wafers supported by the shroud , each wafer of the plurality of wafers including an insulative frame that supports a first terminal pair and a second terminal pair , the first and second terminal pairs each having a first signal terminal and a second signal terminal that form a differential pair, each of the first and second signal terminals having a contact , a tail and a body extending therebetween, the bodies of the first and second signal terminals being edge-coupled and each wafer including a ground shield that provides a U-channel that extends along the body of the signal terminals , wherein each wafer omits separate ground terminals between adjacent terminal pairs and the U-channels of adjacent terminal pairs are electrically connected with a connection frame ; and a plurality of U-shields , each of the U-shields of the plurality of U-shields arranged to partially shield the contacts of one of the terminal pairs , the U-shield electrically connected to the U-channel associated with the corresponding terminal pair , characterized in that each of the U-shields of the plurality of the U-shields is supported by the shroud . a shroud ; a plurality of wafers supported by the shroud , each wafer of the plurality of wafers including an insulative frame that supports a first terminal pair and a second terminal pair , the first and second terminal pairs each having a first signal terminal and a second signal terminal that form a differential pair, each of the first and second signal terminals having a contact , a tail and a body extending therebetween, the bodies of the first and second signal terminals being edge-coupled and each wafer including a ground shield that provides a U-channel that extends along the body of the signal terminals , wherein each wafer omits separate ground terminals between adjacent terminal pairs and the U-channels of adjacent terminal pairs are electrically connected with a connection frame ; and a plurality of U-shields , each of the U-shields of the plurality of U-shields arranged to partially shield the contacts of one of the terminal pairs , the U-shield electrically connected to the U-channel associated with the corresponding terminal pair , characterized in that each of the U-shields of the plurality of the U-shields is supported by the shroud .
Method for geometry measurement of the frog of a turnout of a railway track, by using a measuring train carrying optical means measuring the frog, wherein a correction factor is determined by the use of the optical means measuring the railway track frog and said correction factor is dependent from the horizontal and/or vertical oscillating movement of the measuring train during measuring of the railway track frog and which correction factor is applied to computer calculations for a geometric feature of interest of the measured railway track frog, wherein the optical means comprise light sources of the measuring train which provide emitting of five or more light beams such that during advancement of the measuring train these light beams are projected successively onto the same area of a rail of a railway track and the light beams are substantially simultaneously projected onto the rail which light beams provide onto the rail light lines in a pattern providing at least five spaced light lines, which are present as two sets, and one individual light line, wherein the light lines that are provided onto the rail by the light beams are spaced in longitudinal direction of the rail according to the following: close spacing between two adjacent light lines at least 10 millimeter and not more than 50 millimeter, e.g. approximately 30 millimeter; wide spacing between two adjacent light lines at least 400 millimeter and not more than 800 millimeter, e.g. approximately 600 millimeter; spacing between the two outermost light lines not more than 1400 millimeter, e.g. approximately 1200 millimeter and applying: one light line approximately centrally between two other light lines; two of the light lines with close spacing, separated from the other light lines by at least the wide spacing; the two sets, each of two light lines having the close spacing, wherein these two sets are mutually separated by at least the wide spacing; and the individual light line separated from the other light lines by at least the wide spacing; and wherein the indiviual light line for which the wide spacing with all the other light lines applies is associated with two or more profile cameras and is provided by at least two light emitters, e.g. lasers, such that this light line projected on the rail is simultaneously scanned by a group of at least two cameras and each of the two sets of light lines having the close spacing are associated with a single camera, such that the camera simultaneously detects both light lines, wherein these light lines are projected at the light detecting part of the camera at different locations such that they are detected separately and are discriminated by the camera. one light line approximately centrally between two other light lines; two of the light lines with close spacing, separated from the other light lines by at least the wide spacing; the two sets, each of two light lines having the close spacing, wherein these two sets are mutually separated by at least the wide spacing; and the individual light line separated from the other light lines by at least the wide spacing;
A motorized tensioning device for adjusting a tensioning member in an article, comprising: a motor and a gear reduction system , wherein the motor is configured to drive the gear reduction system ; comprising a spool configured to wind a tensioning member, wherein the spool can rotate in a first rotational direction for tightening the tensioning member and wherein the spool can rotate in a second rotational direction opposite the first direction for loosening the tensioning member; a torque transmitting system capable of transmitting torque from the gear reduction system to the spool so that torque generated by the motor can be used to rotate the spool in the first rotational direction; wherein the torque transmitting system is operable in an incremental tighten mode where torque generated by the motor is used to rotate the spool in the first rotational direction and thereby tighten the tensioning member; wherein the torque transmitting system is operable in an incremental loosen mode where the tension in the tensioning member is incrementally decreased; and characterized in that the torque transmitting system is operable in a full loosen mode in which substantially no torque is transmitted from the torque transmitting system to the spool . a motor and a gear reduction system , wherein the motor is configured to drive the gear reduction system ; comprising a spool configured to wind a tensioning member, wherein the spool can rotate in a first rotational direction for tightening the tensioning member and wherein the spool can rotate in a second rotational direction opposite the first direction for loosening the tensioning member; a torque transmitting system capable of transmitting torque from the gear reduction system to the spool so that torque generated by the motor can be used to rotate the spool in the first rotational direction; wherein the torque transmitting system is operable in an incremental tighten mode where torque generated by the motor is used to rotate the spool in the first rotational direction and thereby tighten the tensioning member; wherein the torque transmitting system is operable in an incremental loosen mode where the tension in the tensioning member is incrementally decreased; and characterized in that the torque transmitting system is operable in a full loosen mode in which substantially no torque is transmitted from the torque transmitting system to the spool .
Shaft lock having a radially inner rotor part which is centrically connected to a shaft having a rotation axis , wherein the shaft and the radially inner rotor part are at least partially enclosed in a coaxial manner by a stationary and radially outer stator part , wherein in a locking state and in a holding state a form-fitting connection between the radially inner rotor part and the stationary and radially outer stator part is able to be established by means of a plurality of locking members , and the form-fitting connection is able to be cancelled for transitioning to an unlocking state, and wherein the locking members for establishing or cancelling the form-fitting connection in regions are able to be partially moved in a form-fitting manner into one respective receptacle geometry of the radially inner rotor part by means of at least one activation member , characterized in that the at least one activation member is designed as a substantially hollow-cylindrical locking ring which radially outside partially encloses the stationary and radially inner stator part in a coaxial manner.
Dumbbell having a dumbbell bar which acts as a handle and end weight plates which can be fitted onto the dumbbell bar or attached to the dumbbell bar and which can be replaced with different weights in each case, wherein the weight plate has an outer face which in the fitted state is orientated outwards, characterised in that the outer face is formed by means of an asymmetrically weight-loaded flywheel which is supported on the weight plate , parallel therewith, so as to be able to be rotated about a centre axis in such a manner that it always assumes the same orientation or angular position, and wherein the handle which is formed by the dumbbell bar or which surrounds the dumbbell bar can be rotated with respect to the weight plates .
A method of loading one or more blades of one or more wind turbines onto a cargo aircraft , comprising: passing a package that includes one or more blades of one or more wind turbines into an interior cargo bay defined by a fuselage of a cargo aircraft ; securing the package at a location within the interior cargo bay such that a center of gravity of the package is located proximate to a center of gravity of the cargo aircraft ; and positioning the package at the location using one or more pre-formed markings in the interior cargo bay , the one or more pre-formed markings being located such that the one or more pre-formed markings designate the location for the package at which the center of gravity of the package is located proximate to the center of gravity of the cargo aircraft. passing a package that includes one or more blades of one or more wind turbines into an interior cargo bay defined by a fuselage of a cargo aircraft ; securing the package at a location within the interior cargo bay such that a center of gravity of the package is located proximate to a center of gravity of the cargo aircraft ; and positioning the package at the location using one or more pre-formed markings in the interior cargo bay , the one or more pre-formed markings being located such that the one or more pre-formed markings designate the location for the package at which the center of gravity of the package is located proximate to the center of gravity of the cargo aircraft.
A load relocation method, applied to a scenario in which some or all user equipment, UEs, served by an original access management entity are to-be-moved to a target access management entity, the method comprising: receiving, by a session management entity currently serving one of the UEs to-be-moved to the target access management entity, from the original access management entity, an identifier of the original access management entity and an address of the target access management entity; and sending , by the session management entity based on the identifier of the original access management entity, a message addressed to the UE to the target access management entity. receiving, by a session management entity currently serving one of the UEs to-be-moved to the target access management entity, from the original access management entity, an identifier of the original access management entity and an address of the target access management entity; and sending , by the session management entity based on the identifier of the original access management entity, a message addressed to the UE to the target access management entity.
Motor vehicle starter comprising a brush holder comprising a rotor shaft, at least one first electrically conductive cage (13.1, 13.3) receiving a first brush (15.1, 15.3) of first polarity, at least one second cage (13.2, 13.4) receiving a second brush (15.2, 15.4) of second polarity different from the first polarity, at least one support plate to which the first (13.1, 13.3) and the second (13.2, 13.4) cages are fixed, said support plate being linked electrically to the second polarity, and a heat-sensitive member that is deformable from a predetermined temperature, said deformable member is arranged to electrically isolate said first cage (13.1, 13.3) with respect to said support plate , following a deformation of said deformable member , a contact between said first cage (13.1, 13.3) and said support plate is established, said deformable member is formed by a layer of electrically insulating material at least partly covering a fixing system for fixing said first cage (13.1, 13.3) to said support plate and the starter comprises a displacement means for displacing said first cage so as to establish the contact following the deformation.
A blood treatment device for treating a patient's blood comprising an apparatus configured to control the blood treatment device in accordance with or based on one or more values of a first parameter calculated or approximated or estimated by a method carried out by the apparatus, the apparatus being configured to carry out said method, the method comprising the steps: - interpolating or extrapolating of at least one later value of the first parameter, taking into account - at least one earlier value of the first parameter, - at least one earlier and at least one later value of a second parameter, and - a mathematical relation between the first and the second parameter, and - controlling the blood treatment device in accordance with or based on the at least one calculated or approximated or estimated value; wherein the first parameter is only one parameter selected from a group of parameters, the group consisting of the overhydration (OH) and the relative overhydration (relOH), and wherein the second parameter is the preweight (before treatment). - interpolating or extrapolating of at least one later value of the first parameter, taking into account - at least one earlier value of the first parameter, - at least one earlier and at least one later value of a second parameter, and - a mathematical relation between the first and the second parameter, and - at least one earlier value of the first parameter, - at least one earlier and at least one later value of a second parameter, and - a mathematical relation between the first and the second parameter, and - controlling the blood treatment device in accordance with or based on the at least one calculated or approximated or estimated value;
A vibratory floor installed in a container , and made up of at least one shaker module , each shaker module including at least one motor-driven vibrator secured to a metal sheet , the metal sheet bearing on a filler material when the vibratory floor bears a load, and on compression springs when the vibratory floor is not loaded, characterized in that the increase in the inner volume of each shaker module during an emptying cycle is offset using an outer pipe of the vibratory floor relative to a clean air contribution outside the container , and in that the outer pipe serves as a passage sheath for an electrical power cable of a motor-driven vibrator . characterized in that the increase in the inner volume of each shaker module during an emptying cycle is offset using an outer pipe of the vibratory floor relative to a clean air contribution outside the container , and in that the outer pipe serves as a passage sheath for an electrical power cable of a motor-driven vibrator .