mhurhangee/patent-ind-claim-en huggingface dataset:
A method for analyzing antibody-drug conjugate compounds, said method comprising: (i) providing a sample comprising an antibody-drug conjugate compound and an unconjugated drug compound; (ii) exposing the sample to a solid phase extraction column comprising a mixed mode stationary phase; (iii) diluting an eluting solvent from the solid phase extraction column (iv) exposing the sample to a reverse phase chromatography column comprising hydrophobic stationary phase; (v) separating the antibody-drug conjugate compound and the unconjugated drug compound in the sample; (vi) establishing a mass to charge ratio of each of the antibody-drug conjugate compound and the unconjugated drug compound in the sample using mass spectrometry; and (vii) quantifying the amount of unconjugated drug compound in the sample. (i) providing a sample comprising an antibody-drug conjugate compound and an unconjugated drug compound; (ii) exposing the sample to a solid phase extraction column comprising a mixed mode stationary phase; (iii) diluting an eluting solvent from the solid phase extraction column (iv) exposing the sample to a reverse phase chromatography column comprising hydrophobic stationary phase; (v) separating the antibody-drug conjugate compound and the unconjugated drug compound in the sample; (vi) establishing a mass to charge ratio of each of the antibody-drug conjugate compound and the unconjugated drug compound in the sample using mass spectrometry; and (vii) quantifying the amount of unconjugated drug compound in the sample.
An anchoring system for a child safety seat comprising - a first coupling device adapted to engage with a harness of the child safety seat , - a second coupling device adapted to engage with a safety belt of a vehicle, - an anchoring means adapted to anchor the first coupling device and the second coupling device , and - a storage system adapted to store at least one of the first coupling device or the second coupling device , wherein the first coupling device is configured to be placed in a respective active position and in a respective inactive position, wherein in the active position the first coupling device is anchored by the anchoring means and placed in a position for engaging with the harness of the child safety seat, and wherein in the inactive position the first coupling device is stored in the storage system ; wherein the second coupling device is configured to be placed in a respective active position and in a respective inactive position, wherein in the active position the second coupling device is anchored by the anchoring means and placed in a position for engaging with the safety belt of the vehicle, and wherein in the inactive position the second coupling device is stored in the storage system ; wherein the anchoring system is configured to be installed in a seating portion of the child safety seat , wherein the anchoring means is configured such that the active position of the first coupling device is distant from the active position of the second coupling device to accommodate for children of different age and size. - a first coupling device adapted to engage with a harness of the child safety seat , - a second coupling device adapted to engage with a safety belt of a vehicle, - an anchoring means adapted to anchor the first coupling device and the second coupling device , and - a storage system adapted to store at least one of the first coupling device or the second coupling device , wherein the second coupling device is configured to be placed in a respective active position and in a respective inactive position, wherein in the active position the second coupling device is anchored by the anchoring means and placed in a position for engaging with the safety belt of the vehicle, and wherein in the inactive position the second coupling device is stored in the storage system ; wherein the anchoring system is configured to be installed in a seating portion of the child safety seat , wherein the anchoring means is configured such that the active position of the first coupling device is distant from the active position of the second coupling device to accommodate for children of different age and size.
A cooling appliance comprising; an ice maker configured to generate ice cubes, a pipe to supply water to the ice maker , a water damper positioned above the ice maker to receive the water from the pipe and wherein the water damper has a conical shape with a diameter gradually decreasing from top to the bottom, characterized by a guide in the form of a protrusion forming a spiral in a first direction extending in the vertical direction on the inner surface of the water damper guiding the flow of the water to flow at least partially along itself. an ice maker configured to generate ice cubes, a pipe to supply water to the ice maker , a water damper positioned above the ice maker to receive the water from the pipe and wherein the water damper has a conical shape with a diameter gradually decreasing from top to the bottom, characterized by a guide in the form of a protrusion forming a spiral in a first direction extending in the vertical direction on the inner surface of the water damper guiding the flow of the water to flow at least partially along itself.
A centrifugal pump for processing molten urea having: - an inlet adapted to receive molten urea at a suction pressure; - a delivery outlet adapted to allow an output of molten urea at a delivery pressure greater than said suction pressure; wherein said centrifugal pump comprises a heating system adapted to maintain a temperature of the molten urea inside the centrifugal pump greater than a predetermined value, the centrifugal pump being characterised in that it has an intermediate outlet adapted to allow an output of molten urea at an intermediate pressure greater than said suction pressure and lower than said delivery pressure. - an inlet adapted to receive molten urea at a suction pressure; - a delivery outlet adapted to allow an output of molten urea at a delivery pressure greater than said suction pressure; wherein said centrifugal pump comprises a heating system adapted to maintain a temperature of the molten urea inside the centrifugal pump greater than a predetermined value, the centrifugal pump being characterised in that it has an intermediate outlet adapted to allow an output of molten urea at an intermediate pressure greater than said suction pressure and lower than said delivery pressure.
A composition in a form of gel, ointment, cream or emulsion for modulating the optical transmittance of the skin within the ultraviolet spectrum comprising a) one or more materials for setting a minimum value of wavelength of the light transmitted, wherein the one or more materials are selected from carbomer interpolymer type A (Carbopol Ultrez 10 NF polymer), carbomer homopolymer type C (Carbopol 980 NF polymer), zinc-hyaluronate, glycerin, isopropyl myristate, caprylic/capric triglyceride (Miglyol 810), PEG-4 (Macrogol 200), PEG-6 (Macrogol 300), PEG-12 (Macrogol 600), carbomer homopolymer type A (Carbopol 971P NF polymer), propylene glycol, and PEG-8 (Macrogol 400); b) one or more materials for modifying the value of wavelength set by the one or more materials according to 1a) and enhancing the optical transmittance of the skin in a given range of wavelengths, wherein the one or more materials are selected from lactic acid, methenamine, ethoxydiglycol (Transcutol), polyaminopropyl biguanide, sodium hyaluronate, and/or nicotinic acid; c) excipients, which allow the light to penetrate into the skin in a wavelength range above the value relevant for the use, where the excipients are triethanolamine, phenoxyethanol and caprylyl glycol and chlorphenesin (Mikrokill COS), and distilled water for use in UV-B light therapy of dermatological disorders. a) one or more materials for setting a minimum value of wavelength of the light transmitted, wherein the one or more materials are selected from carbomer interpolymer type A (Carbopol Ultrez 10 NF polymer), carbomer homopolymer type C (Carbopol 980 NF polymer), zinc-hyaluronate, glycerin, isopropyl myristate, caprylic/capric triglyceride (Miglyol 810), PEG-4 (Macrogol 200), PEG-6 (Macrogol 300), PEG-12 (Macrogol 600), carbomer homopolymer type A (Carbopol 971P NF polymer), propylene glycol, and PEG-8 (Macrogol 400); b) one or more materials for modifying the value of wavelength set by the one or more materials according to 1a) and enhancing the optical transmittance of the skin in a given range of wavelengths, wherein the one or more materials are selected from lactic acid, methenamine, ethoxydiglycol (Transcutol), polyaminopropyl biguanide, sodium hyaluronate, and/or nicotinic acid; c) excipients, which allow the light to penetrate into the skin in a wavelength range above the value relevant for the use, where the excipients are triethanolamine, phenoxyethanol and caprylyl glycol and chlorphenesin (Mikrokill COS), and distilled water
A steel sheet for the manufacture of a press hardened steel part, the steel sheet having a composition comprising, by weight percent: 0.15 % ≤ C ≤ 0.22 % 3.5 % ≤ Mn < 4.2 % 0.001 % ≤ Si ≤ 1.5 % 0.3 % ≤ Al ≤ 0.9 % 0.001 % ≤ Cr ≤ 1 % 0.001 % ≤ Mo ≤ 0.3 % 0.001 % ≤ Ti ≤ 0.040 % 0.0003 % ≤ B ≤ 0.004 % 0.001 % ≤ Nb ≤ 0 .060% 0.001 % ≤ N ≤ 0 .009% 0.0005 % ≤ S ≤ 0 .003% 0.001 % ≤ P ≤ 0 .020% optionally 0.0001 % ≤ Ca ≤ 0 .003 % , the remainder being iron and unavoidable impurities, said steel sheet having a microstructure consisting of, in surface fraction: less than 50% of ferrite, between 1% and 20% of retained austenite, wherein the fraction of the retained austenite is determined according to the method described in the description, cementite, such that the surface density of cementite particles having a larger dimension higher than 60 nm is lower than 10^7/mm 2 ,wherein the surface density of cementite particles having a larger dimension higher than 60 nm is determined according to the method described in the description, a complement consisting of bainite and/or martensite, the retained austenite having an average Mn content of at least 1.1*Mn%, wherein Mn% designates the Mn content in the steel composition. the remainder being iron and unavoidable impurities, said steel sheet having a microstructure consisting of, in surface fraction: less than 50% of ferrite, between 1% and 20% of retained austenite, wherein the fraction of the retained austenite is determined according to the method described in the description, cementite, such that the surface density of cementite particles having a larger dimension higher than 60 nm is lower than 10^7/mm 2 ,wherein the surface density of cementite particles having a larger dimension higher than 60 nm is determined according to the method described in the description, a complement consisting of bainite and/or martensite, less than 50% of ferrite, between 1% and 20% of retained austenite, wherein the fraction of the retained austenite is determined according to the method described in the description, cementite, such that the surface density of cementite particles having a larger dimension higher than 60 nm is lower than 10^7/mm 2 ,wherein the surface density of cementite particles having a larger dimension higher than 60 nm is determined according to the method described in the description, a complement consisting of bainite and/or martensite, the retained austenite having an average Mn content of at least 1.1*Mn%, wherein Mn% designates the Mn content in the steel composition.
Directly compressible co-mixtures comprising fine-grained polyvinyl alcohols (PVAs) having an average particle size D v50 in the range from 50 to 260 μm and fine-grained microcrystalline celluloses (MCCs) having average particle sizes of D v50 <70 μm, particularly preferably having average particle sizes in the range from D v50 17 to 67 μm, in particular in the range from D v50 17 μm - 20 μm.
A head mountable device for measuring eye movement, the head mountable device comprising: - a frame ; - a camera system comprising a first camera , wherein the camera system is configured to obtain a first set of images of a first eye of a user, wherein the first set of images is configured to be obtained with a first frame rate, wherein the first frame rate is selected such as to enable detection of eye saccades of the first eye; a first liquid crystal display (LCD) shutter configured to control passage of light to at least part of the first eye based on a first control signal , the first LCD shutter is configured to operate in a first primary mode and a first secondary mode, where passage of light through the first LCD shutter in the first secondary mode is restricted relative to the first primary mode, wherein the head mountable device further comprises a second liquid crystal display (LCD) shutter configured to control passage of light to at least part of a second eye of the user based on a second control signal , the second LCD shutter is configured to operate in a second primary mode and a second secondary mode, where passage of light through the second LCD shutter in the second secondary mode is restricted relative to the second primary mode, characterized in that the first LCD shutter is configured to control passage of light through the first LCD shutter based on the first control signal and a common control signal and in that the second LCD shutter is configured to control passage of light through the second LCD shutter based on the second control signal and said common control signal , where the first control signal , the second control signal and the common control signal are voltage signals. - a frame ; - a camera system comprising a first camera , wherein the camera system is configured to obtain a first set of images of a first eye of a user, wherein the first set of images is configured to be obtained with a first frame rate, wherein the first frame rate is selected such as to enable detection of eye saccades of the first eye;
Device for attaching a bracelet to a watch case , the device comprising, on the one hand, a bar formed by at least one telescopic cylindrical shaft secured to the watch case by means of at least one horn , and on the other hand, an insert integral with the end of a bracelet, the bar and the insert being complementary to cooperate by interlocking or fitting with each other to form removable assembly means capable of making the bracelet interchangeable, characterized in that the bar has at least one flat portion , said flat portion being arranged to cooperate by interlocking or fitting with at least one housing made in said at least one insert , said at least one housing having a substantially rectangular opening for receiving said at least one flat portion , said shaft being telescopic in order to move from a first position A, in which the shaft is deployed and the insert is positionable on the shaft , to a second position B, in which the shaft is retracted and said insert is locked on the bar shaft .
Assembly comprising an obstacle , an antenna configured to transmit and/or receive electromagnetic waves of wavelength λ, and a device , intended to be subjected to an incident electromagnetic wave of wavelength λ transmitted by said antenna , wherein: - the obstacle is formed of an electrically conductive material and takes a substantially cylindrical shape of longitudinal axis (0; ez), which longitudinal axis is substantially perpendicular to a direction of propagation of the incident electromagnetic wave, said obstacle furthermore having a maximum transverse dimension d such that the ratio d/λ is lower than 1; - the device is placed over all or part of a surface of the obstacle so as to decrease a radar cross section of said obstacle, and includes: o a sleeve of a dielectric coating , of equivalent relative dielectric permittivity ε req , of height h p , along a longitudinal axis of said sleeve, which is substantially equal to λ ε req 2 ; o a sleeve of an electrically conductive coating placed around the periphery of the dielectric coating , of the same height h p along a longitudinal axis of said sleeve as the height of the dielectric coating sleeve. - the obstacle is formed of an electrically conductive material and takes a substantially cylindrical shape of longitudinal axis (0; ez), which longitudinal axis is substantially perpendicular to a direction of propagation of the incident electromagnetic wave, said obstacle furthermore having a maximum transverse dimension d such that the ratio d/λ is lower than 1; - the device is placed over all or part of a surface of the obstacle so as to decrease a radar cross section of said obstacle, and includes: o a sleeve of a dielectric coating , of equivalent relative dielectric permittivity ε req , of height h p , along a longitudinal axis of said sleeve, which is substantially equal to λ ε req 2 ; o a sleeve of an electrically conductive coating placed around the periphery of the dielectric coating , of the same height h p along a longitudinal axis of said sleeve as the height of the dielectric coating sleeve. o a sleeve of a dielectric coating , of equivalent relative dielectric permittivity ε req , of height h p , along a longitudinal axis of said sleeve, which is substantially equal to λ ε req 2 ; o a sleeve of an electrically conductive coating placed around the periphery of the dielectric coating , of the same height h p along a longitudinal axis of said sleeve as the height of the dielectric coating sleeve.
An air-cooling drop pill production line comprising a drop pill system, an air-cooling circulation system and a control system, wherein the drop pill system comprises a molten material tank and a dripper connected thereto, and a vibration apparatus being arranged between the molten material tank and the dripper , the vibration apparatus being adapted to drive the dripper to vibrate up and down and a generated vibration shear force cuts liquor flowing out from the dripper into drops, the air-cooling circulation system being adapted to form drop pills when the drops fall into the air-cooling circulation system and are cooled, characterized in that an online monitoring apparatus being arranged on the dripper and comprising a pulse signal emission mechanism with an emission frequency which is the same as a vibration frequency of the vibration apparatus , the control system being adapted to control and regulate a dropping parameter according to a monitoring result of the online monitoring apparatus , and the online monitoring apparatus is arranged on a lower side face of the dripper ; and the pulse signal emission mechanism is a stroboscopic lamp with the emission frequency which is the same as the vibration frequency of the vibration apparatus .
A modular armor system , comprising: a ballistics-grade armor panel for providing ballistics protections, said ballistics-grade armor panel having an outer strike face and an inner surface opposite the outer strike face , the ballistics-grade armor panel providing ballistics protection, said ballistics-grade armor panel comprising a periphery having sides (14, 15, 16, 17; 104, 105, 106, 107) which define an area of said periphery; and at least one hook or loop fastening member connected on the outer strike face adjacent each side of the periphery (14,15, 16, 17; 104, 105, 106, 107) of the ballistics-grade armor panel for detachably coupling the ballistics- grade armor panel to a structure for providing ballistic protection, wherein the modular armor system further comprises a step in the ballistics-grade armor panel extending inward from the outer strike face , and characterized in that the at least one hook or loop fastening member comprises a plurality of hook or loop type fastening tabs coupled to the step and overhanging edges of the ballistics-grade armor panel . a ballistics-grade armor panel for providing ballistics protections, said ballistics-grade armor panel having an outer strike face and an inner surface opposite the outer strike face , the ballistics-grade armor panel providing ballistics protection, said ballistics-grade armor panel comprising a periphery having sides (14, 15, 16, 17; 104, 105, 106, 107) which define an area of said periphery; and at least one hook or loop fastening member connected on the outer strike face adjacent each side of the periphery (14,15, 16, 17; 104, 105, 106, 107) of the ballistics-grade armor panel for detachably coupling the ballistics- grade armor panel to a structure for providing ballistic protection, wherein the modular armor system further comprises a step in the ballistics-grade armor panel extending inward from the outer strike face , and characterized in that the at least one hook or loop fastening member comprises a plurality of hook or loop type fastening tabs coupled to the step and overhanging edges of the ballistics-grade armor panel .
Sensor arrangement (100; 400; 500; 600; 700; 800; 900; 1000; 1100; 1200), comprising a substrate having a through opening between a first and a second main surface region thereof, a sound transducing portion arranged at the first main surface region of the substrate and at least partially spanning the through opening in the substrate , wherein the sound transducing portion comprises a deflectable membrane structure , and an counter electrode , and a pressure sensing portion arranged at the first main surface region of the substrate and fluidically coupled to the through opening in the substrate , wherein the pressure sensing portion comprises a first and second rigid electrode and a deflectable membrane structure in a stacked configuration, wherein the deflectable membrane structure of the pressure sensing portion opposes a plane of the first main surface region of the substrate , and wherein the first and second rigid electrodes of the pressure sensing portion form a reference capacitor of the pressure sensing portion , and wherein the second rigid electrode and the membrane structure form a sense capacitor of the pressure sensing portion in a stacked configuration. a substrate having a through opening between a first and a second main surface region thereof, a sound transducing portion arranged at the first main surface region of the substrate and at least partially spanning the through opening in the substrate , wherein the sound transducing portion comprises a deflectable membrane structure , and an counter electrode , and a pressure sensing portion arranged at the first main surface region of the substrate and fluidically coupled to the through opening in the substrate , wherein the pressure sensing portion comprises a first and second rigid electrode and a deflectable membrane structure in a stacked configuration, wherein the deflectable membrane structure of the pressure sensing portion opposes a plane of the first main surface region of the substrate , and wherein the first and second rigid electrodes of the pressure sensing portion form a reference capacitor of the pressure sensing portion , and wherein the second rigid electrode and the membrane structure form a sense capacitor of the pressure sensing portion in a stacked configuration. wherein the pressure sensing portion comprises a first and second rigid electrode and a deflectable membrane structure in a stacked configuration, wherein the deflectable membrane structure of the pressure sensing portion opposes a plane of the first main surface region of the substrate , and wherein the first and second rigid electrodes of the pressure sensing portion form a reference capacitor of the pressure sensing portion , and wherein the second rigid electrode and the membrane structure form a sense capacitor of the pressure sensing portion in a stacked configuration.