A method for obtaining a high-resolution image of a region of interest, the method comprising: obtaining, using one or more processors, a first image from a first camera; identifying, using the one or more processors, a region of interest within the first image; configuring, using the one or more processors, a second camera to capture partial-frame images of a sampling area containing the region of interest, wherein the sampling area consists of some, but not all, of a field of view of the second camera, wherein a field of view of the first camera fully encompasses the field of view of the second camera; obtaining, using the one or more processors, a second image from the first camera; comparing, using the one or more processors, the first and second image; determining, using the one or more processors, in dependence on the comparison, whether the region of interest has moved within the field of view of the second camera; and reconfiguring, using the one or more processors, one or more of the size, shape, or location of the sampling area to contain the region of interest if the region of interest has moved while the second camera is capturing the partial-frame images of the sampling area; receiving, using the one or more processors, a plurality of images captured by the second camera; and creating, using the one or more processors, an enhanced image of the region of interest from the plurality of images captured by the second camera, wherein a resolution of the region of interest within the enhanced image is higher than a resolution of the region of interest within any one of the plurality of images captured by the second camera. obtaining, using one or more processors, a first image from a first camera; identifying, using the one or more processors, a region of interest within the first image; configuring, using the one or more processors, a second camera to capture partial-frame images of a sampling area containing the region of interest, wherein the sampling area consists of some, but not all, of a field of view of the second camera, wherein a field of view of the first camera fully encompasses the field of view of the second camera; obtaining, using the one or more processors, a second image from the first camera; comparing, using the one or more processors, the first and second image; determining, using the one or more processors, in dependence on the comparison, whether the region of interest has moved within the field of view of the second camera; and reconfiguring, using the one or more processors, one or more of the size, shape, or location of the sampling area to contain the region of interest if the region of interest has moved while the second camera is capturing the partial-frame images of the sampling area; receiving, using the one or more processors, a plurality of images captured by the second camera; and creating, using the one or more processors, an enhanced image of the region of interest from the plurality of images captured by the second camera, wherein a resolution of the region of interest within the enhanced image is higher than a resolution of the region of interest within any one of the plurality of images captured by the second camera. <EOS>