mhurhangee/patent-ind-claim-en huggingface dataset:
Device for the cryogenic separation of air with a main heat exchanger and a counter-current subcooler , with a distillation column system for nitrogen-oxygen separation , which comprises a high-pressure column and a low-pressure column, and with a mixing column and with means for introducing feed air via the main heat exchanger into the high-pressure column and into the mixing column, with a liquid-oxygen line for introducing liquid oxygen from the low-pressure column into the upper region of the mixing column and with an oxygen product line for extracting oxygen gas from the upper region of the mixing column through the main heat exchanger, the mixing column and the counter-current subcooler being arranged in the common cold box , the mixing column being arranged above the counter-current subcoder , the common cold box enclosing the mixing column , the counter-current subcooler , the high-pressure column and the low-pressure column, and the high-pressure column and the low-pressure column being arranged one above the other .
A method of detecting Chlamydia trachomatis in a test sample, the method comprising: (a) extracting nucleic acid from the test sample; (b) amplifying a target sequence by reacting the nucleic acid extracted in step (a) with a reaction mixture comprising a strand displacement DNA polymerase and a sequence-specific primer set, wherein said sequence-specific primer set is selected from the group consisting of Set-1 and Set-10; and (c) detecting the presence or absence of an amplified product of step (b); wherein the presence of said amplification product is indicative of the presence of Chlamydia trachomatis in the test sample, wherein: (i) Set-1 consists of a forward inner primer (FIP) comprising SEQ ID NO: 3, a backward inner primer (BIP) comprising SEQ ID NO: 4, a forward outer primer (F3) comprising SEQ ID NO: 1, a backward outer primer (B3) comprising SEQ ID NO: 2, a forward loop primer (LF) comprising SEQ ID NO: 5 and a backward loop primer (LB) comprising SEQ ID NO: 6, and (ii) Set-10 consists of a forward inner primer (FIP) comprising SEQ ID NO: 3, a backward inner primer (BIP) comprising SEQ ID NO: 4, a forward loop primer (LF) comprising SEQ ID NO: 5 and a backward loop primer (LB) comprising SEQ ID NO: 6. (a) extracting nucleic acid from the test sample; (b) amplifying a target sequence by reacting the nucleic acid extracted in step (a) with a reaction mixture comprising a strand displacement DNA polymerase and a sequence-specific primer set, wherein said sequence-specific primer set is selected from the group consisting of Set-1 and Set-10; and (c) detecting the presence or absence of an amplified product of step (b); wherein the presence of said amplification product is indicative of the presence of Chlamydia trachomatis in the test sample, (i) Set-1 consists of a forward inner primer (FIP) comprising SEQ ID NO: 3, a backward inner primer (BIP) comprising SEQ ID NO: 4, a forward outer primer (F3) comprising SEQ ID NO: 1, a backward outer primer (B3) comprising SEQ ID NO: 2, a forward loop primer (LF) comprising SEQ ID NO: 5 and a backward loop primer (LB) comprising SEQ ID NO: 6, and (ii) Set-10 consists of a forward inner primer (FIP) comprising SEQ ID NO: 3, a backward inner primer (BIP) comprising SEQ ID NO: 4, a forward loop primer (LF) comprising SEQ ID NO: 5 and a backward loop primer (LB) comprising SEQ ID NO: 6.
A system for opening and closing a door within a cabinet, comprising: a door ; a housing that movably supports the door to enable the door to transition between a fully closed position and an open position, the housing includes opposite first and second side walls , one or both of the first and second side walls includes a track along which a portion of the door moves as the door transitions between the fully closed and open positions; a carrier ; the housing supports a motor , which is operatively engaged with a transmission , the transmission being aligned such that rotation of a motor shaft of the motor causes the carrier to linearly translate between a rear position and a forward position, wherein the door is in the open position when the carrier is in the rear position; a bracket connected to the door , characterized in that the system further comprises a spring connected between the carrier and the bracket ; wherein the bracket is configured to move linearly with respect to the carrier , the spring biases the bracket to a forward position with respect to the carrier ; wherein when the carrier is urged in a forward direction and the door movement toward the fully closed position is blocked, the bracket is prevented from sliding with the carrier , which causes the spring to elongate as the carrier continues to move in the forward direction. a door ; a housing that movably supports the door to enable the door to transition between a fully closed position and an open position, the housing includes opposite first and second side walls , one or both of the first and second side walls includes a track along which a portion of the door moves as the door transitions between the fully closed and open positions; a carrier ; the housing supports a motor , which is operatively engaged with a transmission , the transmission being aligned such that rotation of a motor shaft of the motor causes the carrier to linearly translate between a rear position and a forward position, wherein the door is in the open position when the carrier is in the rear position; a bracket connected to the door , characterized in that the system further comprises a spring connected between the carrier and the bracket ; wherein the bracket is configured to move linearly with respect to the carrier , the spring biases the bracket to a forward position with respect to the carrier ; wherein when the carrier is urged in a forward direction and the door movement toward the fully closed position is blocked, the bracket is prevented from sliding with the carrier , which causes the spring to elongate as the carrier continues to move in the forward direction.
Electrosurgical instrument , particularly hybrid instrument with fluid injection function, having a distal end piece that comprises a distal end surface and a passage channel , whereby the distal end surface surrounds a mouth opening at which the passage channel opens out, having a holder that is linearly movably arranged in the passage channel between a retracted position (I) in which the holder is arranged distant from the end surface and an extended position (II) in which the holder ends flush with the end surface or projects beyond it, wherein the holder comprises a seat opening , having an electrode that is arranged with one section in the seat opening and is held to project therefrom with another section . having a distal end piece that comprises a distal end surface and a passage channel , whereby the distal end surface surrounds a mouth opening at which the passage channel opens out, having a holder that is linearly movably arranged in the passage channel between a retracted position (I) in which the holder is arranged distant from the end surface and an extended position (II) in which the holder ends flush with the end surface or projects beyond it, wherein the holder comprises a seat opening , having an electrode that is arranged with one section in the seat opening and is held to project therefrom with another section .
A mesh element for an atomiser assembly , the mesh element comprising: a first layer defining at least one channel , the at least one channel comprising a minimum cross-sectional area; and a second layer overlying the first layer , wherein the second layer defines at least one nozzle comprising a maximum cross-sectional area, and wherein the second layer comprises an inner surface facing the first layer and an outer surface facing away from the first layer ; wherein the at least one nozzle overlies the at least one channel , and wherein the maximum cross-sectional area of the at least one nozzle is smaller than the minimum cross-sectional area of the at least one channel ; wherein the outer surface of the second layer defines an annular portion extending around the at least one nozzle , wherein the annular portion has a semi-circular cross-sectional shape, and wherein a thickness of the second layer at each annular portion is larger than a thickness of the second layer between adjacent annular portions . a first layer defining at least one channel , the at least one channel comprising a minimum cross-sectional area; and a second layer overlying the first layer , wherein the second layer defines at least one nozzle comprising a maximum cross-sectional area, and wherein the second layer comprises an inner surface facing the first layer and an outer surface facing away from the first layer ; wherein the at least one nozzle overlies the at least one channel , and wherein the maximum cross-sectional area of the at least one nozzle is smaller than the minimum cross-sectional area of the at least one channel ; wherein the outer surface of the second layer defines an annular portion extending around the at least one nozzle , wherein the annular portion has a semi-circular cross-sectional shape, and wherein a thickness of the second layer at each annular portion is larger than a thickness of the second layer between adjacent annular portions .
A process for the preparation of N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine dihydrochloride of formula-I comprising the steps of: a) selective demethylation of 6,7-dimethoxy-quinazoline-4 -one of formula-XIII using de-methylating agent to get 6-hydroxy-7-methoxy-quinazoline-4 -one of formula-XIV, b) converting 6-hydroxy-7-methoxy-quinazoline-4 -one of formula-XIV to 4-(3-ethynylanilino)-7-methoxy-quinazolin-6-ol of formula-XVIII, c) condensing 4-(3-ethynylanilino)-7-methoxy-quinazolin-6-ol of formula-XVIII with 3-morpholinopropyl chloride of formula-VI, in dimethylformamide-potassium carbonate medium to get N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine of formula-IV, d) converting N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy) quinazolin-4-amine of formula-IV to dihydrochloride salt of formula-I using hydrochloric acid gas dissolved in organic solvent medium. a) selective demethylation of 6,7-dimethoxy-quinazoline-4 -one of formula-XIII using de-methylating agent to get 6-hydroxy-7-methoxy-quinazoline-4 -one of formula-XIV, b) converting 6-hydroxy-7-methoxy-quinazoline-4 -one of formula-XIV to 4-(3-ethynylanilino)-7-methoxy-quinazolin-6-ol of formula-XVIII, c) condensing 4-(3-ethynylanilino)-7-methoxy-quinazolin-6-ol of formula-XVIII with 3-morpholinopropyl chloride of formula-VI, in dimethylformamide-potassium carbonate medium to get N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine of formula-IV, d) converting N-(3-ethynylphenyl)-7-methoxy-6-(3-morpholinopropoxy) quinazolin-4-amine of formula-IV to dihydrochloride salt of formula-I using hydrochloric acid gas dissolved in organic solvent medium.
Spectrometry method comprising the following step: a) for at least one ionizing radiation energy E i , obtaining, for each energy E i , a curve of the number of photons detected, during a measurement interval, as a function of time, by means of a spectrometer , said method being characterized in that it further comprises the following steps: b) for each curve thus obtained, calculating a ratio of the total number of photons detected in at least two defined and distinct periods of time in order to obtain, for each ionizing radiation energy E i , a number a i , or for each curve thus obtained, acquiring one or more fitting parameters PAJ i by making a fit to said corresponding curve with a fitting function, c) comparing each number a i , or each fitting parameter or set of fitting parameters PAJ i thus obtained, with reference constants a i (REF) or, respectively, with reference fitting parameters PAJ i (REF) associated with reference energies E i (REF), in order to determine, for each number a i or each fitting parameter or set of fitting parameters PAJ i , the reference energy E i (REF) of the ionizing radiation for which said corresponding curve was measured. a) for at least one ionizing radiation energy E i , obtaining, for each energy E i , a curve of the number of photons detected, during a measurement interval, as a function of time, by means of a spectrometer , said method being characterized in that it further comprises the following steps: b) for each curve thus obtained, calculating a ratio of the total number of photons detected in at least two defined and distinct periods of time in order to obtain, for each ionizing radiation energy E i , a number a i , or for each curve thus obtained, acquiring one or more fitting parameters PAJ i by making a fit to said corresponding curve with a fitting function, c) comparing each number a i , or each fitting parameter or set of fitting parameters PAJ i thus obtained, with reference constants a i (REF) or, respectively, with reference fitting parameters PAJ i (REF) associated with reference energies E i (REF), in order to determine, for each number a i or each fitting parameter or set of fitting parameters PAJ i , the reference energy E i (REF) of the ionizing radiation for which said corresponding curve was measured.
A humidifying device humidifying liner paper transported in one direction and affixed to medium paper via a glue applied to an apex of a wave shape of the medium paper formed into the wave shape, the device being suitable for being provided downstream of a preheater of a corrugating machine and comprising: a liquid application roller heating the liner paper prior to the affixing and applying a heated liquid to the liner paper ; and a chamber disposed to face a peripheral face of the liquid application roller and provided with an internal space to which the liquid is supplied, wherein the chamber has an opening communicating with the internal space at a vertically upper part thereof, the opening being for supplying the liquid to the peripheral face of the liquid application roller , wherein a portion in a vertically downward direction of the liquid application roller enters the chamber from the opening to contact the liquid in the chamber, characterized in that a length (W) of the opening in a direction orthogonal to an axial direction of the liquid application roller is less than a diameter of the liquid application roller . a liquid application roller heating the liner paper prior to the affixing and applying a heated liquid to the liner paper ; and a chamber disposed to face a peripheral face of the liquid application roller and provided with an internal space to which the liquid is supplied, wherein the chamber has an opening communicating with the internal space at a vertically upper part thereof, the opening being for supplying the liquid to the peripheral face of the liquid application roller , wherein a portion in a vertically downward direction of the liquid application roller enters the chamber from the opening to contact the liquid in the chamber, characterized in that a length (W) of the opening in a direction orthogonal to an axial direction of the liquid application roller is less than a diameter of the liquid application roller .
Rail vehicle carriage having a carriage body and a ceiling frame arranged within the carriage body , wherein the ceiling frame has two longitudinal struts which run in the longitudinal direction of the rail vehicle carriage and extend at least through a first region of the carriage body , wherein the ceiling frame has, in the first region of the carriage body , at least one transverse strut which connects the longitudinal struts of the ceiling frame to each other, wherein the longitudinal struts are fastened in the first region to the carriage body using the at least one transverse strut , characterized in that the first region of the carriage body is designed as a high-roof region and a second region of the carriage body is designed as a flat-roof region , wherein the longitudinal struts of the ceiling frame extend through the two regions , and the longitudinal struts are arranged in the two regions at an at least substantially constant height with respect to a plurality of wheel-contact points of the rail vehicle carriage . the ceiling frame has, in the first region of the carriage body , at least one transverse strut which connects the longitudinal struts of the ceiling frame to each other, wherein the longitudinal struts are fastened in the first region to the carriage body using the at least one transverse strut , characterized in that the first region of the carriage body is designed as a high-roof region and a second region of the carriage body is designed as a flat-roof region , wherein the longitudinal struts of the ceiling frame extend through the two regions , and the longitudinal struts are arranged in the two regions at an at least substantially constant height with respect to a plurality of wheel-contact points of the rail vehicle carriage .
Device for viticulture or fruit growing in the form of a trellis post with: - a base surface extending in the longitudinal direction of the trellis post with profiled corrugations , - open flanges , and - reinforcing beads rising in a convex manner from the flanges with supports for tension wires , characterised in that in the area of the trellis post , which is hammered into the ground, - a driving edge is provided along the base surface , and - a cutting edge is provided, arranged in an overhead view over the trellis post in a line of sight along the longitudinal axis of the trellis post and the base surface making a right angle to the driving edge on the flanges , wherein the cutting edge is arranged at an acute angle to the base surface . - a base surface extending in the longitudinal direction of the trellis post with profiled corrugations , - open flanges , and - reinforcing beads rising in a convex manner from the flanges with supports for tension wires , characterised in that in the area of the trellis post , which is hammered into the ground, - a driving edge is provided along the base surface , and - a cutting edge is provided, arranged in an overhead view over the trellis post in a line of sight along the longitudinal axis of the trellis post and the base surface making a right angle to the driving edge on the flanges , wherein the cutting edge is arranged at an acute angle to the base surface .
A method performed by a Fail-Open Function, FOF, , the method comprising: receiving at the FOF , from a charging function, CHF , information corresponding to a subscriber of a network, the information including data indicative of use of the network by the subscriber; storing the information in an offline account database of the FOF ; receiving at the FOF, from a connected function, a request for information about the subscriber associated with a session; determining by the FOF that the CHF is unreachable; based on the request and on determining that the CHF is unreachable, performing by the FOF at least one of accessing or modifying the information stored in the offline account database of the FOF; based on performing at least one of accessing or modifying the information stored in the offline account database of the FOF, generating by the FOF a response ; and transmitting by the FOF the response to the connected function ; determining that the CHF has become reachable; and based on determining that the CHF has become reachable, transmitting, to the CHF, an indication of the information that has been at least one of accessed or modified. receiving at the FOF , from a charging function, CHF , information corresponding to a subscriber of a network, the information including data indicative of use of the network by the subscriber; storing the information in an offline account database of the FOF ; receiving at the FOF, from a connected function, a request for information about the subscriber associated with a session; determining by the FOF that the CHF is unreachable; based on the request and on determining that the CHF is unreachable, performing by the FOF at least one of accessing or modifying the information stored in the offline account database of the FOF; based on performing at least one of accessing or modifying the information stored in the offline account database of the FOF, generating by the FOF a response ; and transmitting by the FOF the response to the connected function ; determining that the CHF has become reachable; and based on determining that the CHF has become reachable, transmitting, to the CHF, an indication of the information that has been at least one of accessed or modified.
A prodrug represented by the general formula or a pharmaceutically acceptable salt thereof, wherein: R 1 represents (C 1 -C 10 )alkyl, (C 1- C 10 )alkoxy, (C 1 -C 10 )alkyl-C(O)-(C 1 -C 10 )alkyl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkyl(C 1 -C 10 )alkyl, aryl, aryl(C 1 -C 10 )alkyl, heteroaryl, or heteroaryl(C 1 -C 10 )alkyl, wherein any R 1 is optionally substituted with one or more substituents independently selected from the group consisting of halo, hydroxy, carboxylate, cyano, amino, nitro, and thio (-SH); R 2 represents H or a (C 1 -C 6 )alkyl; R 3 represents (C 1 -C 6 )alkyl; R 4 is absent or represents a (C 1 -C 6 )alkyl, -OH, -NH 2 , or one or two halogens; X represents O or S; Cyt' represents an anthracycline moiety; and L represents a bond or -N(H)-L represents a self-immolative linker which is metabolized after FAP cleavage to release the anthracycline moiety, wherein the prodrug is selectively converted to an active anthracycline by FAP + stromal cells. R 1 represents (C 1 -C 10 )alkyl, (C 1- C 10 )alkoxy, (C 1 -C 10 )alkyl-C(O)-(C 1 -C 10 )alkyl, (C 3 -C 8 )cycloalkyl, (C 3 -C 8 )cycloalkyl(C 1 -C 10 )alkyl, aryl, aryl(C 1 -C 10 )alkyl, heteroaryl, or heteroaryl(C 1 -C 10 )alkyl, wherein any R 1 is optionally substituted with one or more substituents independently selected from the group consisting of halo, hydroxy, carboxylate, cyano, amino, nitro, and thio (-SH); R 2 represents H or a (C 1 -C 6 )alkyl; R 3 represents (C 1 -C 6 )alkyl; R 4 is absent or represents a (C 1 -C 6 )alkyl, -OH, -NH 2 , or one or two halogens; X represents O or S; Cyt' represents an anthracycline moiety; and L represents a bond or -N(H)-L represents a self-immolative linker which is metabolized after FAP cleavage to release the anthracycline moiety, wherein the prodrug is selectively converted to an active anthracycline by FAP + stromal cells.
An ink cartridge receiving module adapted for supplying ink to an industrial printing machine, having a plurality of receiving spaces for receiving a plurality of ink cartridges , each receiving space having a bottom surface , each receiving space further having a connector adapted for removing ink from the respective cartridge , the connectors being arranged at the lower side of the receiving spaces , characterized in that the bottom surface is inclined at an angle between 10° and 45° with respect to a horizontal plane.