An ultrasonic treatment apparatus, comprising: - a therapy ultrasound transducer (ATA), suitable for generating focused ultrasonic waves; - an imaging ultrasound transducer (UID) associated with the therapy ultrasound transducer; and - an electronic system configured to: - control the therapy ultrasound transducer so as to emit a pulse train of ultrasonic waves of an energy and a duration suitable for causing the generation of a cloud of cavitation bubbles (BC) in a focal spot (TF) of the transducer when said focal spot is positioned inside a region to be treated of a human or animal body; - control the imaging ultrasound transducer so as to emit, between two ultrasonic-wave pulses emitted by the therapy ultrasound transducer, ultrasonic waves that are directed toward the region to be treated, to acquire echoes of said ultrasonic waves and to process them to reconstruct at least one image of the region to be treated; - acquire a plurality of echo signals of N>1 ultrasonic-wave pulses emitted by the therapy ultrasound transducer, which signals are captured by the imaging ultrasound transducer; - process said echo signals of the N ultrasonic-wave pulses emitted by the therapy ultrasound transducer using a beamforming algorithm, so as to form respective echo images (F 1 - F N ), and using spatio-temporal filtering allowing components of said echo images that are representative of a backscatter of the ultrasonic-wave pulses by the cavitation bubbles to be extracted, separating them from components representative of a backscatter by tissues of the region to be treated, so as to reconstruct an image (IBC) of the cloud of cavitation bubbles; and - display, superposed on said image of the region to be treated, said image of the cloud of cavitation bubbles. - a therapy ultrasound transducer (ATA), suitable for generating focused ultrasonic waves; - an imaging ultrasound transducer (UID) associated with the therapy ultrasound transducer; and - an electronic system configured to: - control the therapy ultrasound transducer so as to emit a pulse train of ultrasonic waves of an energy and a duration suitable for causing the generation of a cloud of cavitation bubbles (BC) in a focal spot (TF) of the transducer when said focal spot is positioned inside a region to be treated of a human or animal body; - control the imaging ultrasound transducer so as to emit, between two ultrasonic-wave pulses emitted by the therapy ultrasound transducer, ultrasonic waves that are directed toward the region to be treated, to acquire echoes of said ultrasonic waves and to process them to reconstruct at least one image of the region to be treated; - acquire a plurality of echo signals of N>1 ultrasonic-wave pulses emitted by the therapy ultrasound transducer, which signals are captured by the imaging ultrasound transducer; - process said echo signals of the N ultrasonic-wave pulses emitted by the therapy ultrasound transducer using a beamforming algorithm, so as to form respective echo images (F 1 - F N ), and using spatio-temporal filtering allowing components of said echo images that are representative of a backscatter of the ultrasonic-wave pulses by the cavitation bubbles to be extracted, separating them from components representative of a backscatter by tissues of the region to be treated, so as to reconstruct an image (IBC) of the cloud of cavitation bubbles; and - display, superposed on said image of the region to be treated, said image of the cloud of cavitation bubbles. <EOS>