A side-load air filter cartridge comprising: a) a media pack configured for installation into a side opening of an air cleaner housing , the media pack extending along a longitudinal axis (X) between an inlet end and an outlet end, the media pack defining an outer perimeter; b) a seal arrangement operatively positioned with respect to the media pack , the seal arrangement defining an axial seal surface facing towards the outlet flow end, a portion of which is arranged at an oblique angle to the longitudinal axis; c) a first connection member configured to engage with a first lock mechanism of the air cleaner to secure the media pack within the air cleaner housing , the first connection member being operably connected to the media pack with a portion of the first connection member extending axially beyond the media pack outlet flow end ; and d) a second connection member located opposite the first connection member and configured to engage with a second lock mechanism of the air cleaner to additionally secure the media pack within the air cleaner housing , the second connection member being operably connected to the media pack with a portion of the second connection member extending axially beyond the media pack inlet flow end ; e) wherein the first and second connection members are operable to respectively engage with the first and second lock mechanisms to axially align and fix the filter cartridge within the housing to effectuate a seal between the seal arrangement and the housing; and f) a cover portion , wherein one or both of the first and second connection members are provided on the cover portion . a) a media pack configured for installation into a side opening of an air cleaner housing , the media pack extending along a longitudinal axis (X) between an inlet end and an outlet end, the media pack defining an outer perimeter; b) a seal arrangement operatively positioned with respect to the media pack , the seal arrangement defining an axial seal surface facing towards the outlet flow end, a portion of which is arranged at an oblique angle to the longitudinal axis; c) a first connection member configured to engage with a first lock mechanism of the air cleaner to secure the media pack within the air cleaner housing , the first connection member being operably connected to the media pack with a portion of the first connection member extending axially beyond the media pack outlet flow end ; and d) a second connection member located opposite the first connection member and configured to engage with a second lock mechanism of the air cleaner to additionally secure the media pack within the air cleaner housing , the second connection member being operably connected to the media pack with a portion of the second connection member extending axially beyond the media pack inlet flow end ; e) wherein the first and second connection members are operable to respectively engage with the first and second lock mechanisms to axially align and fix the filter cartridge within the housing to effectuate a seal between the seal arrangement and the housing; and f) a cover portion , wherein one or both of the first and second connection members are provided on the cover portion . <EOS>