mhurhangee/patent-ind-claim-en huggingface dataset:
An improved MAT (iMAT) molecule, comprising: (i) at least one first module being an amino acid sequence allowing the translocation of the iMAT molecule from the extracellular space into the interior of cells, wherein the at least one first module is selected from the group consisting of: (i) the amino acid sequence of HIV-tat, VP22 and/or Antennapedia, (ii) the amino acid sequence according to SEQ ID NO: 1; (ii) at least one second module being an amino acid sequence allowing species-specific intracellular targeting of the iMAT molecule to the cell organelles which are involved in the processing of antigens and/or the loading of MHC molecules with antigens, wherein such at least one second module comprises, preferably consists of, one of the amino acid sequences selected from the group consisting of: SEQ ID NOS: 2, 15, 16; and (iii) at least one third module as antigen module being an amino acid sequence derived from at least one full or partial epitope of at least one antigen, wherein such at least one antigen is an allergen derived from blood feeding insects from the genus culicoides, wherein such at least one antigen is Cul o2 and/or Cul o3 allergen, preferably are the amino acid sequences according to SEQ ID NOS: 5 and/or 6, characterized in that in the entire iMAT molecule all cysteine residues are substituted with a different amino acid residue selected from the group consisting of serine, leucine, isoleucine and/or aspartic acid. (i) at least one first module being an amino acid sequence allowing the translocation of the iMAT molecule from the extracellular space into the interior of cells, wherein the at least one first module is selected from the group consisting of: (i) the amino acid sequence of HIV-tat, VP22 and/or Antennapedia, (ii) the amino acid sequence according to SEQ ID NO: 1; (ii) at least one second module being an amino acid sequence allowing species-specific intracellular targeting of the iMAT molecule to the cell organelles which are involved in the processing of antigens and/or the loading of MHC molecules with antigens, wherein such at least one second module comprises, preferably consists of, one of the amino acid sequences selected from the group consisting of: SEQ ID NOS: 2, 15, 16; and (iii) at least one third module as antigen module being an amino acid sequence derived from at least one full or partial epitope of at least one antigen, wherein such at least one antigen is an allergen derived from blood feeding insects from the genus culicoides, wherein such at least one antigen is Cul o2 and/or Cul o3 allergen, preferably are the amino acid sequences according to SEQ ID NOS: 5 and/or 6,
A method for producing a decorative profiled element, in particular an edge strip for coating the narrow faces of furniture panels, wherein a prefabricated substrate made of at least partially thermoplastic material is provided, wherein a film of thermoplastic material is produced, wherein the film will be printed and/or is printed with a decorative pattern, characterized in that the printed film is welded directly to the substrate without subsequent application of an adhesive, bonding or sealing layer, forming the decorative profiled element, by heating the prefabricated substrate by heat input at least in certain regions and welding the printed film to the substrate after heating and/or during heating. wherein a prefabricated substrate made of at least partially thermoplastic material is provided, wherein a film of thermoplastic material is produced, wherein the film will be printed and/or is printed with a decorative pattern, characterized in that the printed film is welded directly to the substrate without subsequent application of an adhesive, bonding or sealing layer, forming the decorative profiled element, by heating the prefabricated substrate by heat input at least in certain regions and welding the printed film to the substrate after heating and/or during heating.
A light module of a headlamp for a motor vehicle, comprising - several semiconductor light sources that can be individually activated, and are disposed in the manner of a matrix, adjacent to and/or above one another, for emitting light, - several primary optics disposed in the manner of a matrix, adjacent to and/or above one another, allocated to the semiconductor light sources , for bundling at least a portion of the light emitted by the semiconductor light sources , and - a shared secondary optic (18; 36) for projecting secondary light distributions on a roadway in front of the motor vehicle, such that the secondary light distributions illuminate a high-beam region, wherein the secondary light distributions exhibit vertical light/dark borders generated by the secondary optic (18; 36), and wherein primary light distributions are producible on light exit surfaces of the primary optics , which can be projected onto the roadway in front of the vehicle by the secondary optics (18; 36) as the secondary light distributions , characterised in that a cylindrical optic (30; 33), which exhibits substantially no refraction in the horizontal cross-sections and exhibits light collecting characteristics in the vertical cross-sections, is disposed in the beam path of the light module between the primary optics and the secondary optic (18; 36). - several semiconductor light sources that can be individually activated, and are disposed in the manner of a matrix, adjacent to and/or above one another, for emitting light, - several primary optics disposed in the manner of a matrix, adjacent to and/or above one another, allocated to the semiconductor light sources , for bundling at least a portion of the light emitted by the semiconductor light sources , and - a shared secondary optic (18; 36) for projecting secondary light distributions on a roadway in front of the motor vehicle, such that the secondary light distributions illuminate a high-beam region, wherein the secondary light distributions exhibit vertical light/dark borders generated by the secondary optic (18; 36), and wherein primary light distributions are producible on light exit surfaces of the primary optics , which can be projected onto the roadway in front of the vehicle by the secondary optics (18; 36) as the secondary light distributions , characterised in that a cylindrical optic (30; 33), which exhibits substantially no refraction in the horizontal cross-sections and exhibits light collecting characteristics in the vertical cross-sections, is disposed in the beam path of the light module between the primary optics and the secondary optic (18; 36).
A composition for use in promoting local muscle growth, slowing or preventing local muscle atrophy is characterized in that the composition comprises a first polypeptide; a second polypeptide; and a linker between the first polypeptide and the second polypeptide, wherein the sequence of the first polypeptide, the linker and the second polypeptide is set forth in SEQ ID NO: 17.
A compound represented by the following Formula 1 or a pharmaceutically acceptable salt thereof: wherein, in the above formula, R 1 is hydrogen or halogen; R 2 is linear or branched C 1-6 alkyl; and R 3 to R 7 are each independently hydrogen, halogen, linear or branched C 1-6 alkyl, linear or branched C 1-6 haloalkyl, C 1-6 alkoxy, or C 1-6 haloalkoxy. R 1 is hydrogen or halogen; R 2 is linear or branched C 1-6 alkyl; and R 3 to R 7 are each independently hydrogen, halogen, linear or branched C 1-6 alkyl, linear or branched C 1-6 haloalkyl, C 1-6 alkoxy, or C 1-6 haloalkoxy.
Braking system comprising a brake pad , said pad comprising a backing plate with a first face and a second face , and a lining made of friction material and fixed to said first face , the lining being delimited by a friction face , a mounting face , an inner edge , an outer edge , a rear edge , and a front edge , said lining being provided with at least one collection groove which is open to the friction face , which extends from its first end of said inner edge and which emerges at its second end of said outer edge and on said outer edge , said braking system being characterized in that it further comprises a collection system which comprises a collection pipe through which air is able to flow, the air inlet orifice of said collection pipe being located opposite said second end .
A method for constructing an elevator system comprising an elevator drive machine , an elevator car , a counterweight and at least one flexible suspension means in a building, with at least one lifting operation being carried out in said method in order to adapt the usable lifting height of the elevator system to an increasing height of the building, with a drive platform that carries the elevator drive machine , as well as the elevator car and the counterweight with the aid of the suspension means , being raised in said lifting operation, and with a difference between a suspension means weight (F A ) of the suspension means on the side of the elevator car and a suspension means weight (F G ) of the suspension means on the counterweight side essentially being compensated in said method with the aid of at least one compensating traction means that extends from the underside of the elevator car to the underside of the counterweight via a deflecting device , characterized in that the deflecting device comprises two roller assemblies , which respectively have at least one deflecting roller (41, 42, 43, 44; 41, 42, 43, 44, 70, 71, 72, 73), with the at least one compensating traction means extending over at least one respective deflecting roller of the two roller assemblies in such a way that it forms at least one compensating traction means loop , in which a defined amount of the compensating traction means is stored, and in that a distance between the two roller assemblies is reduced prior to and/or during the lifting operation in order to release an amount of the compensating traction means required for carrying out the lifting operation from the at least one compensating traction means loop .
Method for manufacturing a carpet or a rug, wherein the method comprises at least the following steps: - the step (S1-S2) of providing a primary backing ; - the step of providing a glue layer ; - the step of tufting yarn at least into said primary backing ; - the step of activating said glue layer at least for partially fixing said yarn on said primary backing ; characterized in that - said primary backing is a woven or non-woven layer comprising, filaments of polyethylene terephtalate and copolymer of polyethylene terephtalate, wherein the coPET has a lower melting temperature than the PET and wherein said PET is available in said primary backing in an amount of at least 60 weight percent; - said glue layer is a layer having a polymer content that comprises 60 weight percent or more of coPET. - the step (S1-S2) of providing a primary backing ; - the step of providing a glue layer ; - the step of tufting yarn at least into said primary backing ; - the step of activating said glue layer at least for partially fixing said yarn on said primary backing ; characterized in that - said primary backing is a woven or non-woven layer comprising, filaments of polyethylene terephtalate and copolymer of polyethylene terephtalate, wherein the coPET has a lower melting temperature than the PET and wherein said PET is available in said primary backing in an amount of at least 60 weight percent; - said glue layer is a layer having a polymer content that comprises 60 weight percent or more of coPET.
A system comprising: an imaging device comprising an optical coherence tomography light source, wherein the imaging device is configured to obtain an image of intravascular tissue comprising plaque; and a non-transitory computer readable medium configured to cause a processor to: analyze a pixel of the image with a first neural network configured to classify the plaque as a first tissue type of a plurality of tissue types; analyze the pixel of the image with a second neural network configured to classify the plaque as a second tissue type of the plurality of tissue types; and analyze the pixel of the image with a third neural network configured to classify the plaque as a third tissue type of the plurality of tissue types, wherein histological data from the plurality of tissue types is analyzed to characterize tissue types of pixels selected to train the first, second and third neural networks. an imaging device comprising an optical coherence tomography light source, wherein the imaging device is configured to obtain an image of intravascular tissue comprising plaque; and a non-transitory computer readable medium configured to cause a processor to: analyze a pixel of the image with a first neural network configured to classify the plaque as a first tissue type of a plurality of tissue types; analyze the pixel of the image with a second neural network configured to classify the plaque as a second tissue type of the plurality of tissue types; and analyze the pixel of the image with a third neural network configured to classify the plaque as a third tissue type of the plurality of tissue types, analyze a pixel of the image with a first neural network configured to classify the plaque as a first tissue type of a plurality of tissue types; analyze the pixel of the image with a second neural network configured to classify the plaque as a second tissue type of the plurality of tissue types; and analyze the pixel of the image with a third neural network configured to classify the plaque as a third tissue type of the plurality of tissue types, wherein histological data from the plurality of tissue types is analyzed to characterize tissue types of pixels selected to train the first, second and third neural networks.
Support system for fastening an elongate object to a support rail, comprising a clip for fastening the support system to the support rail and a clip attachment , the clip attachment having at least two strain relief portions for at least two-fold strain relief of the object, characterized in that the clip is designed as a snap-in locking device for tool-free fastening to the support rail and/or the clip has such a snap-in locking device.
A method for facilitating Machine-to-Machine, M2M, communication, the method comprising: providing a first M2M system that implements one or more standardized Machine-to-Machine, M2M, Application Programming Interface, API, profiles that include common tasks and specialized tasks; receiving, by the first M2M system, a profile query over a network interface from a second peer M2M system; and responding, by the first M2M system, with information about the implemented one or more M2M API profiles that describe the functionalities it is able to provide, the method further including, without any human intervention: receiving information, by the first M2M system from the second peer M2M system, about an M2M API profile providing server from which a software update for a functionality not currently implemented can be obtained, receiving, from the M2M API profile providing server, the new functionality by the first M2M system, and completing a requested task based on the received new functionality by the first M2M system. providing a first M2M system that implements one or more standardized Machine-to-Machine, M2M, Application Programming Interface, API, profiles that include common tasks and specialized tasks; receiving, by the first M2M system, a profile query over a network interface from a second peer M2M system; and responding, by the first M2M system, with information about the implemented one or more M2M API profiles that describe the functionalities it is able to provide, the method further including, without any human intervention: receiving information, by the first M2M system from the second peer M2M system, about an M2M API profile providing server from which a software update for a functionality not currently implemented can be obtained, receiving, from the M2M API profile providing server, the new functionality by the first M2M system, and completing a requested task based on the received new functionality by the first M2M system. receiving information, by the first M2M system from the second peer M2M system, about an M2M API profile providing server from which a software update for a functionality not currently implemented can be obtained, receiving, from the M2M API profile providing server, the new functionality by the first M2M system, and completing a requested task based on the received new functionality by the first M2M system.
An ultrasonic surgical instrument comprising: an end effector ; a jaw movable relative to the end effector; a transducer assembly comprising at least two piezoelectric elements configured to ultrasonically oscillate the end effector; and an indicium coextensive with a portion of the jaw overlying the end effector; characterised in that the ultrasonic instrument further comprises a first electrode having a first electrical potential and a second electrode having a second electrical potential, wherein a tissue contacting both the first electrode and the second electrode generates a signal, and wherein the ultrasonic instrument further comprises a cooperating surface disposed on the jaw, the cooperating surface is aligned with the end effector, wherein the first electrode is coextensive with the cooperating surface and the second electrode is positioned proximally to the cooperating surface, and wherein there is a gap situated proximally to the cooperating surface of the jaw , and wherein the second electrode corresponds to the position of the gap , and wherein the signal indicates that tissue has been detected in the gap . an end effector ; a jaw movable relative to the end effector; a transducer assembly comprising at least two piezoelectric elements configured to ultrasonically oscillate the end effector; and an indicium coextensive with a portion of the jaw overlying the end effector; characterised in that the ultrasonic instrument further comprises a first electrode having a first electrical potential and a second electrode having a second electrical potential, wherein a tissue contacting both the first electrode and the second electrode generates a signal, and wherein the ultrasonic instrument further comprises a cooperating surface disposed on the jaw, the cooperating surface is aligned with the end effector, wherein the first electrode is coextensive with the cooperating surface and the second electrode is positioned proximally to the cooperating surface, and wherein there is a gap situated proximally to the cooperating surface of the jaw , and wherein the second electrode corresponds to the position of the gap , and wherein the signal indicates that tissue has been detected in the gap .
An associative cache memory, comprising: an array of storage elements arranged as M sets by N ways; an allocation unit that allocates the storage elements of the array in response to memory accesses that miss in the cache memory, wherein each of the memory accesses selects a set of the M sets; wherein each of the memory accesses has an associated memory access type, MAT, of a plurality of predetermined memory access types, MATs, wherein the MAT is received by the cache memory; wherein each valid storage element of the array has an associated MAT of the plurality of predetermined MATs; means for mapping that includes, for each MAT of the plurality of predetermined MATs, a MAT priority; wherein in response to a memory access that misses in the array, the allocation unit configured to: determine a most eligible way and a second most eligible way of the selected set for replacement based on a replacement policy; and replace the second most eligible way rather than the most eligible way when the MAT priority of the most eligible way is greater than the MAT priority of the second most eligible way. an array of storage elements arranged as M sets by N ways; an allocation unit that allocates the storage elements of the array in response to memory accesses that miss in the cache memory, wherein each of the memory accesses selects a set of the M sets; wherein each of the memory accesses has an associated memory access type, MAT, of a plurality of predetermined memory access types, MATs, wherein the MAT is received by the cache memory; wherein each valid storage element of the array has an associated MAT of the plurality of predetermined MATs; means for mapping that includes, for each MAT of the plurality of predetermined MATs, a MAT priority; wherein in response to a memory access that misses in the array, the allocation unit configured to: determine a most eligible way and a second most eligible way of the selected set for replacement based on a replacement policy; and replace the second most eligible way rather than the most eligible way when the MAT priority of the most eligible way is greater than the MAT priority of the second most eligible way. determine a most eligible way and a second most eligible way of the selected set for replacement based on a replacement policy; and replace the second most eligible way rather than the most eligible way when the MAT priority of the most eligible way is greater than the MAT priority of the second most eligible way.
A pneumatic tire comprising: a tread composed of a cap tread and a base tread, wherein the cap tread is formed of a rubber composition comprising 30 to 120 parts by mass of silica having 180 to 280 m 2 /g of a BET specific surface area, measured by a BET method according to ASTM D3037-93, based on 100 parts by mass of a rubber component comprising 10% by mass or more and less than 30% by mass of a natural rubber, and wherein C and B satisfy the following inequality , 150 ≤ C/B × 100 ≤ 900 where C represents a ratio (% by mass) of a mass of the cap tread to a total mass of the tread, and B represents a ratio (% by mass) of a mass of the base tread to the total mass of the tread. a tread composed of a cap tread and a base tread, wherein the cap tread is formed of a rubber composition comprising 30 to 120 parts by mass of silica having 180 to 280 m 2 /g of a BET specific surface area, measured by a BET method according to ASTM D3037-93, based on 100 parts by mass of a rubber component comprising 10% by mass or more and less than 30% by mass of a natural rubber, and wherein C and B satisfy the following inequality , 150 ≤ C/B × 100 ≤ 900 where C represents a ratio (% by mass) of a mass of the cap tread to a total mass of the tread, and B represents a ratio (% by mass) of a mass of the base tread to the total mass of the tread.
Underframe for a rail vehicle wagon body, comprising a plurality of longitudinal beams , which are oriented in the longitudinal direction of the underframe , and at least one crossmember which is oriented perpendicularly with respect to the longitudinal beams in the installed position, the longitudinal beams comprising in each case one opening at the mounting position of the crossmember , through which opening the crossmember can be plugged, characterized in that the crossmember can be rotated in the openings about its longitudinal axis, the crossmember being situated in its final mounting position after the termination of the rotational movement , and the longitudinal beams are connected to the crossmember at the intersections to this crossmember by means of a welding method. the crossmember can be rotated in the openings about its longitudinal axis, the crossmember being situated in its final mounting position after the termination of the rotational movement , and the longitudinal beams are connected to the crossmember at the intersections to this crossmember by means of a welding method.