mhurhangee/patent-ind-claim-en huggingface dataset:
A radiolabelled phenyltropane in vivo imaging agent for use in a method for differential diagnosis of Parkinson's disease (PD) from multiple system atrophy Parkinsonian type (MSA-P) and progressive supranuclear palsy (PSP) in a subject wherein said method comprises: (a) administering said radiolabelled phenyltropane in vivo imaging agent to said subject; (b) obtaining an in vivo image of the uptake of said in vivo imaging agent in the brain of said subject; (c) determining a binding ratio for selected striatal and extrastriatal regions of interest (ROIs), wherein said binding ratio is the uptake in each of said ROIs relative to non-specific binding in the brain, wherein said striatal ROIs comprise the caudate nucleus and the putamen, and said extrastriatal ROIs comprise the thalamus, the hypothalamus and the pons; (d) combining the binding ratios determined in step (c) using a voxel-by-voxel whole brain approach of multivariate pattern analysis to obtain a single value for said subject; (e) comparing said single value with a receiver operating characteristic (ROC) curve wherein said ROC curve has been generated from a set of single values obtained using steps (a)-(d) from a group of subjects known to have either PD or one of MSA-P or PSP; (f) differentiating PD from MSA-P or PSP where said single value is above a threshold value of said ROC curve; wherein said subject is not being treated with a serotonin reuptake inhibitor (SSRI). (a) administering said radiolabelled phenyltropane in vivo imaging agent to said subject; (b) obtaining an in vivo image of the uptake of said in vivo imaging agent in the brain of said subject; (c) determining a binding ratio for selected striatal and extrastriatal regions of interest (ROIs), wherein said binding ratio is the uptake in each of said ROIs relative to non-specific binding in the brain, wherein said striatal ROIs comprise the caudate nucleus and the putamen, and said extrastriatal ROIs comprise the thalamus, the hypothalamus and the pons; (d) combining the binding ratios determined in step (c) using a voxel-by-voxel whole brain approach of multivariate pattern analysis to obtain a single value for said subject; (e) comparing said single value with a receiver operating characteristic (ROC) curve wherein said ROC curve has been generated from a set of single values obtained using steps (a)-(d) from a group of subjects known to have either PD or one of MSA-P or PSP; (f) differentiating PD from MSA-P or PSP where said single value is above a threshold value of said ROC curve; wherein said subject is not being treated with a serotonin reuptake inhibitor (SSRI).
A non-stationary magnetic field emitter comprising an at least partially ferrite core and a conductor , whereby the conductor with at least three threads is wound on the core , and the core has an oblong transverse cross-section, where a width of the cross-section of the core is at least three times more than a height of the cross-section of the core and a length of the core is at least 10 times more that a height of the core , the non-stationary magnetic field emitter being characterized in that the conductor is wound on the core with a changing distance (p, pitch) between the middles of two adjacent threads of the conductor in such a way that the distance (p, pitch) between the middles of two adjacent threads increases for each following thread from a middle zone of the core towards an end of the core .
Method of producing open seam tubes (4; 104) from sheet-metal plates , particularly thick sheet-metal plates, wherein a sheet-metal plate is fed to a tube shaping press in which, while resting on a lower tool , it is shaped by a raisable and lowerable upper tool by application of a bending force to progressively form the open seam tube (4; 104) having longitudinal edges lying opposite by a gap (11; 111) for later longitudinal seam welding, wherein an open seam tube with a non-round preform is produced in that a shaping is undertaken in at least one bending step acting on the inner side of the sheet-metal plate respectively to the left and right referred to the centre predetermined by the longitudinal axis of the upper tool entering into the progressively shaped sheet-metal plate , characterised in that the individual contour is determined for each sheet-metal plate, whereupon with use of a geometric model for the righthand and lefthand side of the open seam tube parameters for the support tube positioning, particularly the rotational angle and/or the rotational length are determined as well as the yield strength at each side of the sheet-metal plate through on-line recordal and evaluation of the pressure/path profile during the reshaping, and the dimension of the bending step acting respectively at the left and right on the inner side of the sheet-metal plate is determined therefrom. an open seam tube with a non-round preform is produced in that a shaping is undertaken in at least one bending step acting on the inner side of the sheet-metal plate respectively to the left and right referred to the centre predetermined by the longitudinal axis of the upper tool entering into the progressively shaped sheet-metal plate , characterised in that the individual contour is determined for each sheet-metal plate, whereupon with use of a geometric model for the righthand and lefthand side of the open seam tube parameters for the support tube positioning, particularly the rotational angle and/or the rotational length are determined as well as the yield strength at each side of the sheet-metal plate through on-line recordal and evaluation of the pressure/path profile during the reshaping, and the dimension of the bending step acting respectively at the left and right on the inner side of the sheet-metal plate is determined therefrom.
A precatalyst of formula (I), or a salt or solvate thereof: wherein in (I): each occurrence of M is independently selected from the group consisting of Pd and Pt, preferably the two occurrences of M are identical; each occurrence of X is independently a ligand, preferably X is an anion, more preferably the two occurrences of X are identical; each occurrence of R is independently selected from the group consisting of ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl, neopentyl, hexyl, cyclopropylmethyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, and substituted phenyl, wherein each substituted group in R is independently substituted with at least one substituent selected from the group consisting of C 1-6 alkyl, -OH, C 1-6 alkoxy, halo, amino, acetamido, and nitro; with the proviso that each of the 5-membered rings is substituted with at least one independently selected R; Z is CH, CR or N, with the proviso that 0-2 Z groups are N; or the Z groups at the 5- and 6-positions are null and the Z groups at the 4- and 7-positions are independently R; and, n is 1, 2, 3, or 4. each occurrence of M is independently selected from the group consisting of Pd and Pt, preferably the two occurrences of M are identical; each occurrence of X is independently a ligand, preferably X is an anion, more preferably the two occurrences of X are identical; each occurrence of R is independently selected from the group consisting of ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl, neopentyl, hexyl, cyclopropylmethyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, and substituted phenyl, wherein each substituted group in R is independently substituted with at least one substituent selected from the group consisting of C 1-6 alkyl, -OH, C 1-6 alkoxy, halo, amino, acetamido, and nitro; with the proviso that each of the 5-membered rings is substituted with at least one independently selected R; Z is CH, CR or N, with the proviso that 0-2 Z groups are N; or the Z groups at the 5- and 6-positions are null and the Z groups at the 4- and 7-positions are independently R; and, n is 1, 2, 3, or 4.
A process for the production of a polyurethane foam having a resilience of at least 50%, said process comprising reacting (i) a first polyether polyol comprising polyether chains containing no more than 20% ethylene oxide content wherein the remainder of the alkylene oxide content in the polyether chains is derived from propylene oxide and/or butylene oxide, and having a primary hydroxyl content of no more than 20%, a hydroxyl value of at least 40 and a nominal functionality which is at least 2.5 and at most 3.0; (ii) a second polyether polyol comprising polyether chains containing at least 50% ethylene oxide content wherein the remainder of the alkylene oxide content in the polyether chains is derived from propylene oxide and/or butylene oxide; and (iii) one or more aromatic polyisocyanates, in the presence of one or more catalysts having gelling and/or blowing activities.
Method for manufacturing supplementary cementitious material and sequestering CO 2 by carbonating concrete fines comprising the steps: - grinding the concrete fines obtained from crushed concrete demolition waste in a mill at a temperature from 1 to 10 °C above the water dew point in a carbonating atmosphere provided by a gas containing from 10 to 99 Vol.-% CO 2 , - circulating the ground and partially carbonated concrete fines in a fluidized bed reactor connected to the mill as carbonation zone in contact with the carbonating atmosphere, and - withdrawing decarbonated gas and carbonated concrete fines with recirculation of some of the gas and concrete fines to the reactor and/or mill, wherein at least 80 wt.-% of the concrete fines are carbonated. - grinding the concrete fines obtained from crushed concrete demolition waste in a mill at a temperature from 1 to 10 °C above the water dew point in a carbonating atmosphere provided by a gas containing from 10 to 99 Vol.-% CO 2 , - circulating the ground and partially carbonated concrete fines in a fluidized bed reactor connected to the mill as carbonation zone in contact with the carbonating atmosphere, and - withdrawing decarbonated gas and carbonated concrete fines with recirculation of some of the gas and concrete fines to the reactor and/or mill, wherein at least 80 wt.-% of the concrete fines are carbonated.
A method of milling a row of teeth of a toothed gear element with a straight tooth configuration, with a milling cutter which is rotatable about a milling cutter axis and has at its periphery interchangeable cutting inserts which are so arranged that when the milling cutter is approached to the toothed gear element the cutting inserts engage into the gaps between adjacent teeth or generate those gaps, characterised in that a milling cutter is used, in which the cutting inserts in their condition of being mounted to the milling cutter have at least one cutting edge (8a, b) extending radially and perpendicularly relative to the milling cutter axis, wherein upon milling of the tooth profile the milling cutter axis is oriented in a plane perpendicularly to the longitudinal extent of the tooth back and during the engagement movement of the cutting inserts which rotate about the milling cutter axis into the surface or tooth gaps of a toothed gear element it is pivoted in said plane over an angular range which covers the range of all normals to the profile surface (12a, b; 13a, b) of the tooth to be produced.
An apparatus for controlling operation zones of a mining automation system comprising passage control units , PCUs, separating the operation zones , the PCUs being associated with one or more acknowledgement units for providing, based on a user input, an acknowledgement comprising a safety related confirmation that an operation zone can be isolated by the associated PCU , the apparatus comprising at least one processor and at least one memory including computer program code , the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus to perform: - determine a set of passage control units, PCUs, enabling forming of an isolated operation zone of a mining automation system; the apparatus being characterised in that it is further configured to at least to perform: - store an acknowledgement status record comprising zone configuration data comprising identifiers of the PCUs in the set of PCUs in association of an operation zone identifier of the operation zone ; - maintain the stored acknowledgement status record for the set of PCUs, the acknowledgement status record indicating, for each PCU in the set of PCUs, if an acknowledgement has been received from an acknowledgement unit of the PCU; - determine, based on the acknowledgement status record, a PCU associated with two acknowledgement units arranged at both sides of the PCU within the set of PCUs for completing isolation of the operation zone ; - select of the two acknowledgement units associated with the PCU an acknowledgement unit located outside the operation zone to be isolated; and - control, in response to receiving an acknowledgement from the selected acknowledgement unit , a state of the operation zone indicating a mode of activities allowed in operation zone . - determine a set of passage control units, PCUs, enabling forming of an isolated operation zone of a mining automation system; the apparatus being characterised in that it is further configured to at least to perform: - store an acknowledgement status record comprising zone configuration data comprising identifiers of the PCUs in the set of PCUs in association of an operation zone identifier of the operation zone ; - maintain the stored acknowledgement status record for the set of PCUs, the acknowledgement status record indicating, for each PCU in the set of PCUs, if an acknowledgement has been received from an acknowledgement unit of the PCU; - determine, based on the acknowledgement status record, a PCU associated with two acknowledgement units arranged at both sides of the PCU within the set of PCUs for completing isolation of the operation zone ; - select of the two acknowledgement units associated with the PCU an acknowledgement unit located outside the operation zone to be isolated; and - control, in response to receiving an acknowledgement from the selected acknowledgement unit , a state of the operation zone indicating a mode of activities allowed in operation zone .
Air inlet shut-off device for a motor vehicle , the shut-off device comprising a support frame having a first and a second crossmember that are parallel to one another and connected by lateral uprights so as to define at least one opening for the passage of an incoming air flow (F), said device having at least one curtain that is able to move between a closed position in which the curtain at least partially covers the passage opening and an open position in which said curtain allows the incoming air flow (F) to pass through the passage opening, said curtain having an edge fastened to a roller shaft extending on the support frame along one of the sides of the passage opening, the roller shaft being connected to a drive device so as to roll up the curtain around said roller shaft to bring it into the open position and so as to unroll the curtain to bring it into the closed position, the shut-off device also comprising an automatic return system for the curtain , characterized in that the automatic return system for the curtain has: - an element that is elastic in elongation along the rolling axis (A1) of the roller shaft , said elastic element being fastened at a first of its ends to the roller shaft so as to be driven in rotation by said roller shaft and vice versa, - a cylindrical slider intended to move in translation along the rolling axis (A1) of the roller shaft and in rotation about this same axis (A1), said slider being fastened to a second end of the elastic element so as to be driven indirectly in rotation by the roller shaft and vice versa, said slider also having a helical groove on its outer surface, the support frame having a fixed finger configured to be inserted in the helical groove of the slider . - an element that is elastic in elongation along the rolling axis (A1) of the roller shaft , said elastic element being fastened at a first of its ends to the roller shaft so as to be driven in rotation by said roller shaft and vice versa, - a cylindrical slider intended to move in translation along the rolling axis (A1) of the roller shaft and in rotation about this same axis (A1), said slider being fastened to a second end of the elastic element so as to be driven indirectly in rotation by the roller shaft and vice versa, said slider also having a helical groove on its outer surface, the support frame having a fixed finger configured to be inserted in the helical groove of the slider .
A pellicle for extreme ultraviolet (EUV) lithography, the pellicle comprising: a support layer pattern which is formed by etching a support layer; a pellicle layer which is formed on the support layer pattern ; and an etching stop layer pattern which is formed between the support layer pattern and the pellicle layer and formed by etching an etching stop layer for stopping etching when the support layer is etched; and wherein the pellicle layer comprises a core layer , and one or more reinforcing layers formed on at least one among both surfaces of the core layer and different in material from the core layer ; characterized in that the reinforcing layer comprises an outer porous surface having nano-sized pores. a support layer pattern which is formed by etching a support layer; a pellicle layer which is formed on the support layer pattern ; and an etching stop layer pattern which is formed between the support layer pattern and the pellicle layer and formed by etching an etching stop layer for stopping etching when the support layer is etched; and wherein the pellicle layer comprises a core layer , and one or more reinforcing layers formed on at least one among both surfaces of the core layer and different in material from the core layer ; characterized in that the reinforcing layer comprises an outer porous surface having nano-sized pores.
Hybrid circuit configuration , particularly a protection circuit configuration, comprising at least one first external conductor segment , wherein a first mechanical bypass switch is configured in the first external conductor segment , wherein a first semiconductor switch configuration is connected parallel to the first bypass switch , wherein the hybrid circuit configuration features a first electronic control unit to activate the first semiconductor switch configuration , wherein the hybrid circuit configuration features a bypass switch activation unit , to which bypass switch activation unit at least one field coil of the bypass switch is connected, wherein at least one control terminal of the bypass switch activation unit is connected to the first electronic control unit , and wherein a current measurement unit is configured in the first external conductor segment , which is connected to the electronic control unit , characterized in that the electronic control unit and/or the bypass switch activation unit is designed to control the field coil of the bypass switch in a preconfigured way either with at least one first electric energy or one second electric energy, wherein the second electric energy is greater than the first electric energy, and that, upon detection of a preconfigured strong current, particularly an overcurrent and/or a short circuit current, the electronic control unit and/or the bypass switch activation unit controls the field coil of the bypass switch in the external conductor segment with the second electrical energy.
A removable attachment device comprising a plurality of cells , wherein each cell comprises a contact fixing comprising at least one magnet for attaching the cell to a substrate, and wherein each cell is attached to at least one neighbouring cell by an articulation means therebetween, wherein the device comprises attachment means for attaching an associated article to the cells, the attachment means being located on each cell , and further wherein the articulation allows, when not locked, a degree of rotational movement of a cell about the articulation means to allow removal of the device in stages, such as one cell at a time, whilst providing an attachment strength for supporting objects equal to the sum of the individual cell attachment strengths, characterised in that the device comprises means for mechanically locking a cell to the next to disable the articulation therebetween.
A turning control apparatus for controlling driving of a turning body in a working machine that includes the turning body, a support body that supports the turning body turnably, and a turning drive device that turns the turning body, the turning control apparatus comprising: a target stop position setting unit that sets a target stop position, which is a position at which the turning of the turning body is to be stopped; and a turning command unit that provides an automatic stop command for automatically stopping the turning body at the target stop position to the turning drive device, wherein: the target stop position setting unit includes: an image taking device that is mounted on the working machine and takes an image of the working machine and surroundings thereof; an image processing device that forms an overhead view image of the working machine and a surrounding object positioned around the working machine based on the image taken by the image taking device; an image display device including a display screen capable of displaying the overhead view image; an image display command unit that makes the display screen display a target stop position setting image including the overhead view image; a setting operation member to which a position setting operation for setting the target stop position based on the position of the image of the working machine and the surrounding object included in the overhead view image is applied; and a target stop position determination unit that determines the target stop position based on the position setting operation. a target stop position setting unit that sets a target stop position, which is a position at which the turning of the turning body is to be stopped; and a turning command unit that provides an automatic stop command for automatically stopping the turning body at the target stop position to the turning drive device, wherein: the target stop position setting unit includes: an image taking device that is mounted on the working machine and takes an image of the working machine and surroundings thereof; an image processing device that forms an overhead view image of the working machine and a surrounding object positioned around the working machine based on the image taken by the image taking device; an image display device including a display screen capable of displaying the overhead view image; an image display command unit that makes the display screen display a target stop position setting image including the overhead view image; a setting operation member to which a position setting operation for setting the target stop position based on the position of the image of the working machine and the surrounding object included in the overhead view image is applied; and a target stop position determination unit that determines the target stop position based on the position setting operation.
A lyophilizate composition having improved stability and shelf-life, the lyophilizate consisting of at least from 30 to 100% by weight of Mesna and optionally an excipient.