mhurhangee/patent-ind-claim-en huggingface dataset:
A method of producing HLA homozygous immune cells comprising: (A) obtaining induced pluripotent stem cells (iPSCs), wherein the iPSCs are reprogrammed from a population of HLA homozygous blood cells; (B) differentiating the iPSCs to hematopoietic precursor cells (HPCs); (C) isolating HPCs that express the cell surface markers CD144, CD34, CD45, and CD7; and (D) culturing the HPCs under conditions to promote immune cell differentiation, thereby producing HLA homozygous immune cells, wherein I) the HLA homozygous immune cells are lymphoid cells, and II) culturing the cells to promote lymphoid differentiation comprises: (i) culturing HPCs in defined media on a surface coated with matrix and a Notch ligand; and (ii) maintaining the culture in the presence of one or more cytokines, thereby producing lymphoid cells. (A) obtaining induced pluripotent stem cells (iPSCs), wherein the iPSCs are reprogrammed from a population of HLA homozygous blood cells; (B) differentiating the iPSCs to hematopoietic precursor cells (HPCs); (C) isolating HPCs that express the cell surface markers CD144, CD34, CD45, and CD7; and (D) culturing the HPCs under conditions to promote immune cell differentiation, I) the HLA homozygous immune cells are lymphoid cells, and II) culturing the cells to promote lymphoid differentiation comprises: (i) culturing HPCs in defined media on a surface coated with matrix and a Notch ligand; and (ii) maintaining the culture in the presence of one or more cytokines, thereby producing lymphoid cells. (i) culturing HPCs in defined media on a surface coated with matrix and a Notch ligand; and (ii) maintaining the culture in the presence of one or more cytokines, thereby producing lymphoid cells.
A gas impingement in-process cooling system , comprising: a deposition head (420; 720; 1120) which is movable relative to base materials (411; 711; 1112) and configured to execute a repair operation comprising a deposition of additional materials (421; 721; 1121) onto the base materials during deposition head movements; and a gas impingement assembly comprising impingement diffusers , a support structure to support the impingement diffusers at opposite sides of the base materials (411; 711; 1112) in a trailing position relative to the deposition head (420; 720; 1120) and a supply system configured to supply the impingement diffusers with impingement gas; characterized in that : each impingement diffuser comprises an elongate tubular element with an outer shell that is formed to define perforations , and each impingement diffuser is configured such that impingement gas supplied thereto is directed through the perforations toward the base materials (411; 711; 1112) and the additional materials (421; 721; 1121) in multiple directions. a deposition head (420; 720; 1120) which is movable relative to base materials (411; 711; 1112) and configured to execute a repair operation comprising a deposition of additional materials (421; 721; 1121) onto the base materials during deposition head movements; and a gas impingement assembly comprising impingement diffusers , a support structure to support the impingement diffusers at opposite sides of the base materials (411; 711; 1112) in a trailing position relative to the deposition head (420; 720; 1120) and a supply system configured to supply the impingement diffusers with impingement gas; characterized in that : each impingement diffuser comprises an elongate tubular element with an outer shell that is formed to define perforations , and each impingement diffuser is configured such that impingement gas supplied thereto is directed through the perforations toward the base materials (411; 711; 1112) and the additional materials (421; 721; 1121) in multiple directions.
Lamp comprising - an LED light source for generating a light, - a light guide for guiding the light, - an additional lamp component , wherein the light guide is curved in such a way that it has a convex surface area and a concave surface area and is arranged in such a way that with its concave surface area , it at least partially surrounds the additional lamp component , wherein the lamp furthermore has: - a transparent cover which is shaped and arranged in such a way that it at least partially surrounds the convex surface area of the light guide , - an optically diffusing lobe arranged between the convex surface area of the light guide and the transparent cover , and a carrier element , wherein the cover is designed to be clear and forms a light emission surface of the lamp, characterized in that the cover is arranged to be held on the carrier element via a latching connection, wherein the cover comprises, on its two upper end regions, one latching hook each, which engages the carrier element in a latching manner to form the latching connection in such a way that the light emission surface extends to the upper edge of the lamp. - an LED light source for generating a light, - a light guide for guiding the light, - an additional lamp component , - a transparent cover which is shaped and arranged in such a way that it at least partially surrounds the convex surface area of the light guide , - an optically diffusing lobe arranged between the convex surface area of the light guide and the transparent cover , and
A method of detecting impurities in a refrigerant utilizing a refrigerant analyzer , wherein the refrigerant analyzer includes a first sensing device in flow communication with a second sensing device , the method comprising: (a) splitting the refrigerant into a first refrigerant stream and a second refrigerant stream and passing the first refrigerant stream through a scrubber while not passing the second refrigerant stream through the scrubber ; (b) passing the first refrigerant stream through the first sensing device to detect a first characteristic of the refrigerant of the first refrigerant stream; (c) passing the second refrigerant stream through the first sensing device to detect a first characteristic of the refrigerant of the second refrigerant stream; (d) passing the first refrigerant stream through the second sensing device to detect a second characteristic of the refrigerant of the first refrigerant stream; (e) passing the second refrigerant stream through the second sensing device to detect a second characteristic of the refrigerant of the second refrigerant stream; wherein the first sensing device comprises a non-dispersive infrared sensor and the second sensing device comprises an electrochemical sensor; and (f) determining the presence of a contaminant in the refrigerant based on the characteristics determined in steps (b)-(e). (a) splitting the refrigerant into a first refrigerant stream and a second refrigerant stream and passing the first refrigerant stream through a scrubber while not passing the second refrigerant stream through the scrubber ; (b) passing the first refrigerant stream through the first sensing device to detect a first characteristic of the refrigerant of the first refrigerant stream; (c) passing the second refrigerant stream through the first sensing device to detect a first characteristic of the refrigerant of the second refrigerant stream; (d) passing the first refrigerant stream through the second sensing device to detect a second characteristic of the refrigerant of the first refrigerant stream; (e) passing the second refrigerant stream through the second sensing device to detect a second characteristic of the refrigerant of the second refrigerant stream; wherein the first sensing device comprises a non-dispersive infrared sensor and the second sensing device comprises an electrochemical sensor; and (f) determining the presence of a contaminant in the refrigerant based on the characteristics determined in steps (b)-(e).
A method for controlling a wind turbine , the wind turbine comprising a rotor carrying a set of wind turbine blades and connected to an input shaft, an output shaft connected to a generator , the generator being arranged to supply power to a power grid, and an energy storage system for intermediate storage of energy produced by the generator , the method comprising the steps of: - during full load operation, receiving a power reference value, P ref , representing a power level to be supplied to the power grid by the wind turbine , - controlling the wind turbine in order to produce an output power which is at or near the power reference value, P ref , while maintaining a constant torque on the generator , - in the case that the produced output power of the wind turbine exceeds the power reference value, P ref , storing excess produced energy in the energy storage system and supplying a power level being equal to the power reference value, P ref , to the power grid, - in the case that the produced output power of the wind turbine is below the power reference value, P ref , retrieving stored energy from the energy storage system and supplying a power level being equal to the power reference value, P ref , to the power grid, and characterized by - controlling a pitch angle of the wind turbine blades on the basis of rotational speed. - during full load operation, receiving a power reference value, P ref , representing a power level to be supplied to the power grid by the wind turbine , - controlling the wind turbine in order to produce an output power which is at or near the power reference value, P ref , while maintaining a constant torque on the generator , - in the case that the produced output power of the wind turbine exceeds the power reference value, P ref , storing excess produced energy in the energy storage system and supplying a power level being equal to the power reference value, P ref , to the power grid, - in the case that the produced output power of the wind turbine is below the power reference value, P ref , retrieving stored energy from the energy storage system and supplying a power level being equal to the power reference value, P ref , to the power grid, and characterized by - controlling a pitch angle of the wind turbine blades on the basis of rotational speed.
Fuel injector , in particular common-rail injector, having an injector housing in which there is formed a high-pressure chamber which can be supplied with pressurized fuel via a supply bore arranged in the injector housing , having at least one injection opening , which is connected at least indirectly to the high-pressure chamber and which is formed in the injector housing and which serves for the injection of fuel into the combustion chamber of an internal combustion engine, having an injection member which opens up or closes off the at least one injection opening , and having a measuring device for at least indirectly detecting the pressure in the high-pressure chamber or in the supply bore , wherein the measuring device is designed to detect an elastic deformation of a deformation region which is arranged so as to be at least indirectly operatively connected to the supply bore or to the high-pressure chamber , and wherein the measuring device has a sensor element which is connected to the surface of the deformation region by means of an adhesive connection , wherein the measuring device is covered at least in certain regions by a protective device, and wherein the protective device is formed as a casting compound (40; 40a; 40c) or plastics injection-moulded encapsulation, characterized in that the casting compound (40; 40a; 40c) or plastics injection-moulded encapsulation is, on the side averted from the sensor element , arranged so as to be directly operatively connected to the surroundings or is surrounded by a cover element which is, on the side averted from the sensor element , arranged so as to be directly operatively connected to the surroundings, wherein the casting compound (40; 40a; 40c) or plastics injection-moulded encapsulation is connected to the sensor element such that a pressure force (F) or compressive stress acting in the direction of the sensor element is generated by the casting compound (40; 40a; 40c) or plastics injection-moulded encapsulation, wherein the casting compound (40; 40a; 40c) or plastics injection-moulded encapsulation covers the sensor element on the face surface averted from the injector housing and at the circumferential surface of said sensor element.
A bicycle saddle that can be fastened on a bicycle, comprising: a bicycle saddle shell and a damping layer that is fastened on the bicycle saddle shell , wherein the damping layer comprises an elastic material that is designed for absorbing forces acting upon the bicycle saddle by means of a deformation of the elastic material, wherein the bicycle saddle has a plurality of tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) that are sectionally fastened on the damping layer by means of an integral connection in order to ensure an ergonomic adaptation of the bicycle saddle to an anatomy of a bicyclist and protection of the elastic material of the damping layer , as well as to compensate or cover its unevenness, characterized in that the tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) comprise a first group of tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) with a first rigidity, and in that the tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) comprise a second group of tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) with a second rigidity, wherein the first rigidity is greater than the second rigidity. a bicycle saddle shell and a damping layer that is fastened on the bicycle saddle shell , wherein the damping layer comprises an elastic material that is designed for absorbing forces acting upon the bicycle saddle by means of a deformation of the elastic material, wherein the bicycle saddle has a plurality of tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) that are sectionally fastened on the damping layer by means of an integral connection in order to ensure an ergonomic adaptation of the bicycle saddle to an anatomy of a bicyclist and protection of the elastic material of the damping layer , as well as to compensate or cover its unevenness, characterized in that the tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) comprise a first group of tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) with a first rigidity, and in that the tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) comprise a second group of tape elements (4, 4-3, 4-4, 4-5, 4-6, 4-7) with a second rigidity, wherein the first rigidity is greater than the second rigidity.
A device for cleaning liquid or gaseous media, comprising a cup-shaped or pot-shaped housing , a replaceable separating device arranged in the device to separate a raw medium area from a pure medium area in the device , a medium inlet opening into the raw medium area for the medium to be purified, a medium outlet for purified medium leaving the pure medium area , and a housing lid releasably connected to the housing by connection means , wherein the housing has first circumferential connection means and the housing lid has corresponding second circumferential connection means in an axial overlap area of the housing and the housing lid , the connection means being capable of engaging and disengaging with one another by circumferential turning relatively to one another, and wherein a seal is situated between the housing and the housing lid to seal them against each other when the housing lid is connected to the housing , characterized in that the first connection means or the second connection means has at least one gap extending in the axial direction of the connection means and intersecting the first connection means or the second connection means , that the separating device has at least one positioning arm extending radially outside of the separating device and arranged on the separating device so as to come to rest on a level with the axial overlap area of the housing and the housing lid when the separating device is installed in the device , that with the separating device installed and with the housing connected to the housing lid , the positioning arm is positioned and aligned with the one or more gaps in the connection means and is at least partly accommodated in the gap in the connection means, and that the seal or a seal carrier supporting the seal is attached to the one or more positioning arms or forms an integral part thereof. characterized in that the first connection means or the second connection means has at least one gap extending in the axial direction of the connection means and intersecting the first connection means or the second connection means , that the separating device has at least one positioning arm extending radially outside of the separating device and arranged on the separating device so as to come to rest on a level with the axial overlap area of the housing and the housing lid when the separating device is installed in the device , that with the separating device installed and with the housing connected to the housing lid , the positioning arm is positioned and aligned with the one or more gaps in the connection means and is at least partly accommodated in the gap in the connection means, and that the seal or a seal carrier supporting the seal is attached to the one or more positioning arms or forms an integral part thereof.
A process for making a nanoemulsion comprising: a) an internal phase comprising 40 to 75% by wt. of total nanoemulsion composition of oils selected from the group consisting of triglyceride, petrolatum and mixtures thereof, wherein the melting point of the petrolatum is 30 to 60°C; and 1.5 to 10% by wt. nanoemulsion of a C 8 to C 18 fatty acid; and b) an external aqueous phase comprising: i. 2 to 12% by wt. (as active) of total nanoemulsion composition of a surfactant or surfactants which are N-acyl derivatives of amino acid salt; wherein the surfactant of (i) comprises 65% or greater of trialkanolamine or potassium salts or mixtures thereof of said surfactant; ii. glycerol; and iii. water wherein the weight ratio of glycerol to water in aqueous phase is 3:1 to 1:3; and wherein the volume average diameter of droplets of (a) is 20 to 400 nanometer; wherein said process comprises 1) heating aqueous phase up to 55 to 75°C; 2) and heating oil phases up to 55 to 75°C or until the oil phase is melted; 3) adding the melted oil phase to the aqueous phase with intensive mixing by a conventional rotor/stator device at a rotor speed of 3000 to 7000 rpm till the desired size is reached; and 4) cooling the emulsion to room temperature. a) an internal phase comprising 40 to 75% by wt. of total nanoemulsion composition of oils selected from the group consisting of triglyceride, petrolatum and mixtures thereof, wherein the melting point of the petrolatum is 30 to 60°C; and 1.5 to 10% by wt. nanoemulsion of a C 8 to C 18 fatty acid; and b) an external aqueous phase comprising: i. 2 to 12% by wt. (as active) of total nanoemulsion composition of a surfactant or surfactants which are N-acyl derivatives of amino acid salt; wherein the surfactant of (i) comprises 65% or greater of trialkanolamine or potassium salts or mixtures thereof of said surfactant; ii. glycerol; and iii. water i. 2 to 12% by wt. (as active) of total nanoemulsion composition of a surfactant or surfactants which are N-acyl derivatives of amino acid salt; wherein the surfactant of (i) comprises 65% or greater of trialkanolamine or potassium salts or mixtures thereof of said surfactant; ii. glycerol; and iii. water
A method for controlling an actuatable safety device for protecting an occupant of a vehicle , the method comprising: sensing an impending vehicle collision; in response to sensing the impending vehicle collision, calculating an estimated occupant movement that will result when the impending vehicle collision occurs; controlling the actuatable safety device in response to the estimated occupant movement; and characterized in that sensing the impending vehicle collision comprises receiving an automatic emergency braking (AEB) deceleration flag. sensing an impending vehicle collision; in response to sensing the impending vehicle collision, calculating an estimated occupant movement that will result when the impending vehicle collision occurs; controlling the actuatable safety device in response to the estimated occupant movement; and characterized in that sensing the impending vehicle collision comprises receiving an automatic emergency braking (AEB) deceleration flag.
A dressing, comprising: a barrier layer ; a first fluid management layer coupled to the barrier layer , the first fluid management layer comprising a first plurality of extensions ; a second fluid management layer coupled to the first plurality of extensions , wherein the coupled extensions form a plurality of optically transparent or translucent windows, and a cavity is formed around the coupled extensions and between the first fluid management layer and the second fluid management layer , and wherein one of the fluid management layers comprises a fluid communication point; an absorbent layer disposed in the cavity ; and a patient interface layer coupled to one of the first fluid management layer and the second fluid management layer , the patient interface layer comprising an opening , wherein the opening is at least partially aligned with the fluid communication point. a barrier layer ; a first fluid management layer coupled to the barrier layer , the first fluid management layer comprising a first plurality of extensions ; a second fluid management layer coupled to the first plurality of extensions , wherein the coupled extensions form a plurality of optically transparent or translucent windows, and a cavity is formed around the coupled extensions and between the first fluid management layer and the second fluid management layer , and wherein one of the fluid management layers comprises a fluid communication point; an absorbent layer disposed in the cavity ; and a patient interface layer coupled to one of the first fluid management layer and the second fluid management layer , the patient interface layer comprising an opening , wherein the opening is at least partially aligned with the fluid communication point.
A lithium ion battery module for facilitating retrofitting systems designed to accommodate lead acid batteries, said lithium ion battery module comprising: - a housing , wherein dimensions of the housing conform to overall dimensions for a standard lead acid battery as defined in one of Tables 1, 2, 3, 4, and 5 in the description; - a plurality of hard case prismatic lithium ion battery cells arranged in a stack within the housing ; and - a heat sink outer wall feature of the housing , wherein the heat sink outer wall feature extends in at least one direction up to at least 90 % of an outermost dimension of the standard lead acid battery, wherein the lithium ion battery module includes footings on two sides of the housing and excludes footings on the other sides of the housing in order to accommodate heat transfer components, wherein the heat sink outer wall feature comprises two heat sink plates that form opposite sides of the housing , and wherein the two heat sink plates each include a plurality of fins and wherein the distance between outer surfaces of the plurality of fins on the heat sink plate and outer surfaces of the plurality of fins on the opposite heat sink plate extend to the outermost width dimension of the standard lead acid battery. - a housing , wherein dimensions of the housing conform to overall dimensions for a standard lead acid battery as defined in one of Tables 1, 2, 3, 4, and 5 in the description; - a plurality of hard case prismatic lithium ion battery cells arranged in a stack within the housing ; and - a heat sink outer wall feature of the housing , wherein the heat sink outer wall feature extends in at least one direction up to at least 90 % of an outermost dimension of the standard lead acid battery,