mhurhangee/patent-ind-claim-en huggingface dataset:
A method for measuring the amount of a target protein in a heterogeneous biospecimen having two or more cell types, the method comprising: extracting proteins from a heterogeneous biospecimen; cleaving the proteins to form peptides; analyzing the peptides by mass spectrometry to measure an amount of a proteotypic peptide of a benchmark protein, an amount of a proteotypic peptide of a component-specific protein, and an amount of a proteotypic peptide of a target protein; quantifying an amount of the benchmark protein, an amount of the component-specific protein, and an amount of the target protein in the biospecimen based on the amounts of the corresponding proteotypic peptides; multiplying the amount of the target protein by the ratio of the benchmark protein to the component specific protein to calculate a target value for the target protein in the heterogeneous biospecimen; wherein the benchmark protein is a protein that is expressed at uniform or consistent abundance across multiple samples of a particular type of biospecimen of interest, independent of a cellular and stromal composition of each individual sample, or a protein having similar abundance in all cellular and stromal components of a biospecimen; and the component specific protein is a protein whose expression is unique to or enriched in a cell or stromal component of interest compared to other cell or stromal components of a biospecimen. extracting proteins from a heterogeneous biospecimen; cleaving the proteins to form peptides; analyzing the peptides by mass spectrometry to measure an amount of a proteotypic peptide of a benchmark protein, an amount of a proteotypic peptide of a component-specific protein, and an amount of a proteotypic peptide of a target protein; quantifying an amount of the benchmark protein, an amount of the component-specific protein, and an amount of the target protein in the biospecimen based on the amounts of the corresponding proteotypic peptides; multiplying the amount of the target protein by the ratio of the benchmark protein to the component specific protein to calculate a target value for the target protein in the heterogeneous biospecimen; wherein the benchmark protein is a protein that is expressed at uniform or consistent abundance across multiple samples of a particular type of biospecimen of interest, independent of a cellular and stromal composition of each individual sample, or a protein having similar abundance in all cellular and stromal components of a biospecimen; and the component specific protein is a protein whose expression is unique to or enriched in a cell or stromal component of interest compared to other cell or stromal components of a biospecimen.
A method of decoding video data, the method comprising: partitioning a decoded picture buffer (DPB) into multiple sub-DPBs; receiving, in a video parameter set and for each of a plurality of operation points of a multi-layer video coding process, respectively, at least one indication of a sub-DPB size for a plurality of sub-DPBs for each of the plurality of operation points wherein respective operation points define a highest temporal layer and a set of target output layers of the multi-layer video coding process that are decoded for a particular picture to be output, the layers having layer types, the layer types including a base layer type and one or more enhancement layer types with respect to spatial resolution, bit depth or color format for scalable video coding, or a base view type and one or more reference view types for multi-view video coding, or a base view type and one or more dependent view types with respect to texture and/or depth for 3D video coding; allocating memory space for the plurality of sub-DPBs for a given operation point based on the at least one indication; decoding pictures for a plurality of layers; and storing the pictures for the plurality of layers in the plurality of sub-DPBs, wherein each sub-DPB stores pictures for one type of layer. partitioning a decoded picture buffer (DPB) into multiple sub-DPBs; receiving, in a video parameter set and for each of a plurality of operation points of a multi-layer video coding process, respectively, at least one indication of a sub-DPB size for a plurality of sub-DPBs for each of the plurality of operation points wherein respective operation points define a highest temporal layer and a set of target output layers of the multi-layer video coding process that are decoded for a particular picture to be output, the layers having layer types, the layer types including a base layer type and one or more enhancement layer types with respect to spatial resolution, bit depth or color format for scalable video coding, or a base view type and one or more reference view types for multi-view video coding, or a base view type and one or more dependent view types with respect to texture and/or depth for 3D video coding; allocating memory space for the plurality of sub-DPBs for a given operation point based on the at least one indication; decoding pictures for a plurality of layers; and storing the pictures for the plurality of layers in the plurality of sub-DPBs, wherein each sub-DPB stores pictures for one type of layer.
A method to enhance the attachment of pluripotent stem cells to a surface lacking a feeder cell layer and lacking an adlayer, wherein the method comprises the steps of: a) obtaining a suspension of pluripotent stem cells, b) treating the suspension of pluripotent stem cells with a compound capable of inhibiting Rho kinase activity, and c) adding the suspension of cells to the surface and allowing the pluripotent stem cells to attach; wherein the surface: contains from 1.6% N to 1.8% N, a sum of O and N of 29.6% and a contact angle of 14.3 degrees ±0.4 degrees; contains from 1.8% N to 2.2% N, a sum of O and N of 30.7% and a contact angle of 18.4 degrees ±0.8 degrees; contains from 2.0% N to 2.1% N, a sum of O and N of 30.2% and a contact angle of 17.4 degrees ±2.0 degrees; or contains from 1.6% to 1.9% N, a sum of O and N of 28.2% and a contact angle of 18.8 degrees ± 0.5 degrees. a) obtaining a suspension of pluripotent stem cells, b) treating the suspension of pluripotent stem cells with a compound capable of inhibiting Rho kinase activity, and c) adding the suspension of cells to the surface and allowing the pluripotent stem cells to attach; wherein the surface: contains from 1.6% N to 1.8% N, a sum of O and N of 29.6% and a contact angle of 14.3 degrees ±0.4 degrees; contains from 1.8% N to 2.2% N, a sum of O and N of 30.7% and a contact angle of 18.4 degrees ±0.8 degrees; contains from 2.0% N to 2.1% N, a sum of O and N of 30.2% and a contact angle of 17.4 degrees ±2.0 degrees; or contains from 1.6% to 1.9% N, a sum of O and N of 28.2% and a contact angle of 18.8 degrees ± 0.5 degrees. contains from 1.6% N to 1.8% N, a sum of O and N of 29.6% and a contact angle of 14.3 degrees ±0.4 degrees; contains from 1.8% N to 2.2% N, a sum of O and N of 30.7% and a contact angle of 18.4 degrees ±0.8 degrees; contains from 2.0% N to 2.1% N, a sum of O and N of 30.2% and a contact angle of 17.4 degrees ±2.0 degrees; or contains from 1.6% to 1.9% N, a sum of O and N of 28.2% and a contact angle of 18.8 degrees ± 0.5 degrees.
A rod position indicator system comprising: a drive rod operably coupled to a control rod, wherein the control rod is configured to be both withdrawn from and inserted into a reactor core ; a number of sensing devices (1111-1113, 1121-1123) arranged along a path of the drive rod , wherein an end of the drive rod passes by one or more of the sensing devices (1111-1113, 1121-1123) in response to movement of the control rod with respect to the reactor core , and wherein the sensing devices (1111-1113, 1121-1123) are arranged into a plurality of groups , characterized in that each group comprises two or more of the sensing devices (1111-1113, 1121-1123) that are (i) electrically coupled together and (ii) each positioned at different vertical locations along the path of the drive rod ; and in that the rod position indicator system further comprises a control rod monitoring device electrically coupled to each group of sensing devices (1111-1113, 1121-1123) by a separate routing wire . a drive rod operably coupled to a control rod, wherein the control rod is configured to be both withdrawn from and inserted into a reactor core ; a number of sensing devices (1111-1113, 1121-1123) arranged along a path of the drive rod , wherein an end of the drive rod passes by one or more of the sensing devices (1111-1113, 1121-1123) in response to movement of the control rod with respect to the reactor core , and wherein the sensing devices (1111-1113, 1121-1123) are arranged into a plurality of groups , characterized in that each group comprises two or more of the sensing devices (1111-1113, 1121-1123) that are (i) electrically coupled together and (ii) each positioned at different vertical locations along the path of the drive rod ; and in that the rod position indicator system further comprises a control rod monitoring device electrically coupled to each group of sensing devices (1111-1113, 1121-1123) by a separate routing wire .
A method of communication, comprising: using , at an access terminal, a first non access stratum, NAS, instance to communicate with a first node, wherein the access terminal supports the first NAS instance for communicating with a local MME, wherein the local MME is co-located with a Home eNodeB to facilitate local breakout, wherein the local MME is a reduced functionality MME; using , at the access terminal, a second non access stratum, NAS, instance to communicate with a second node; and accessing a first service based on the communication with the first node and accessing a second service based on the communication with the second node, wherein the first NAS instance and the second NAS instance are routed through the same air interface of the access terminal. using , at an access terminal, a first non access stratum, NAS, instance to communicate with a first node, wherein the access terminal supports the first NAS instance for communicating with a local MME, wherein the local MME is co-located with a Home eNodeB to facilitate local breakout, wherein the local MME is a reduced functionality MME; using , at the access terminal, a second non access stratum, NAS, instance to communicate with a second node; and accessing a first service based on the communication with the first node and accessing a second service based on the communication with the second node, wherein the first NAS instance and the second NAS instance are routed through the same air interface of the access terminal.
Stitch-forming element for a stitch-forming textile machine , the textile machine having a stitch-forming element carrier with at least one guide channel for guiding at least one stitch-forming element , the stitch-forming element having a longitudinal axis and a vertical axis and a first recess with a lower edge , an upper edge , an open first end and a closed second end for stitch formation, wherein the stitch-forming element has a second recess with a lower edge , an upper edge , an open first end and a closed second end , characterised in that the lower edge of the second recess is arranged at an angle to the longitudinal axis for cleaning the at least one guide channel .
Compound 6-chloro-2-ethyl- N -(4-(4-(4-(trifluoromethoxy)phenyl)piperidine-1-yl)benzyl)imidazo[1,2-a]pyridine-3-carboxamide ditosylate having the structure and furthermore having the following peaks in an X-ray Powder Diffraction (XRPD) spectrum obtained by irradiation with Cu-K α - radiation (Cu-K α ): 3.9° 2θ, 5.6° 2θ, 8.0° 2θ, 16.1° 2θ, 19.1° 2θ, and 22.4° 2θ, ± 0.2° 2θ.
A camera photosensitive component, comprising: a silicon substrate layer ; a pixel array layer attached to one surface of the silicon substrate layer ; and a microprism layer arranged in parallel with the pixel array layer , the microprism layer comprising microprisms, wherein the microprisms in the microprism layer are configured to decompose incident light into m color lights for emission, and n color lights in the emitted m color lights are respectively emitted into subpixels in corresponding colors of pixels corresponding to the microprisms, and n is not greater than m; wherein every two adjacent microprisms correspond to two adjacent pixels: a first pixel and a second pixel; wherein the first pixel and the second pixel comprises totally 2n-1 subpixels, and the first pixel and the second pixel share the nth subpixel, and the nth subpixel shared by the first pixel and the second pixel has a larger area than the other subpixels; wherein the first microprism is configured to decompose the incident light into the m color lights for emission, the n color lights in the emitted m color lights are respectively emitted into n-1 subpixels in the corresponding colors of the first pixel and the shared nth subpixel, the second microprism is configured to decompose the incident light into the m color lights for emission, and the n color lights in the emitted m color lights are respectively emitted into n-1 subpixels in the corresponding colors of the second pixel and the shared nth subpixel. a silicon substrate layer ; a pixel array layer attached to one surface of the silicon substrate layer ; and a microprism layer arranged in parallel with the pixel array layer , the microprism layer comprising microprisms, wherein the microprisms in the microprism layer are configured to decompose incident light into m color lights for emission, and n color lights in the emitted m color lights are respectively emitted into subpixels in corresponding colors of pixels corresponding to the microprisms, and n is not greater than m; wherein every two adjacent microprisms correspond to two adjacent pixels: a first pixel and a second pixel; wherein the first pixel and the second pixel comprises totally 2n-1 subpixels, and the first pixel and the second pixel share the nth subpixel, and the nth subpixel shared by the first pixel and the second pixel has a larger area than the other subpixels; wherein the first microprism is configured to decompose the incident light into the m color lights for emission, the n color lights in the emitted m color lights are respectively emitted into n-1 subpixels in the corresponding colors of the first pixel and the shared nth subpixel, the second microprism is configured to decompose the incident light into the m color lights for emission, and the n color lights in the emitted m color lights are respectively emitted into n-1 subpixels in the corresponding colors of the second pixel and the shared nth subpixel.
A layer stack for a magnetic tunnel junction, MTJ, device , the layer stack comprising: a seed layer structure , a pinning layer structure arranged above the seed layer structure , and above the pinning layer structure , a Fe-comprising reference layer structure and a free layer structure separated by a tunnel barrier layer , wherein the seed layer structure comprises a Ru-comprising layer and a Cr-comprising layer , the Cr-comprising layer forming an upper layer of the seed layer structure , and characterized in that the Ru-comprising layer is formed with a thickness in the range of 0.2 to 3 nm and the Cr-comprising layer is formed with a thickness in the range of 0.2 to 2 nm. a seed layer structure , a pinning layer structure arranged above the seed layer structure , and above the pinning layer structure , a Fe-comprising reference layer structure and a free layer structure separated by a tunnel barrier layer , wherein the seed layer structure comprises a Ru-comprising layer and a Cr-comprising layer , the Cr-comprising layer forming an upper layer of the seed layer structure , and characterized in that the Ru-comprising layer is formed with a thickness in the range of 0.2 to 3 nm and the Cr-comprising layer is formed with a thickness in the range of 0.2 to 2 nm.
Pipe connection part for connecting the spigot ends of two pipes , wherein the pipe connection part has two socket regions , wherein each socket region is designed to accommodate one pipe spigot end and has an insertion opening for inserting the pipe spigot ends , wherein a circumferential annular web is arranged along the inner wall and transverse to the longitudinal extension of the pipe connection part between the socket regions of the pipe connection part , wherein the circumferential annular web has an inner collar extending on both sides in the direction of the insertion openings , wherein a circumferential accommodation space is respectively designed on both sides of the annular web between the inner collar , the side walls of the annular web , and sections of the inner wall of the pipe connection part for at least sectional accommodation of the respective pipe spigot end , wherein the socket regions respectively have at least one circumferential annular bead for receiving at least one annular seal , wherein the outer sides of the annular beads , in particular the outer side of the bead base, form, at least in sections, a circumferential rib on the outer side of the pipe connection part , characterized in that the ribs , formed by the outer sides of the annular beads , have a smaller outer diameter than the adjacent rib arranged further in the direction of the insertion opening , and that the ribs , formed by the outer sides of the annular beads , have a larger outer diameter than the adjacent reinforcing rib arranged further in the direction toward the middle of the pipe connection part .
A labeling apparatus having a conveyor belt for transporting packages, having a labeler to apply labels to the packages from below, and having a pullout apparatus which comprises a pullout which is supported via a pullout guide at a stationary pullout carrier and which is linearly travelable relative thereto between a retracted end position and an extended end position, wherein the labeler is positioned on the pullout , and wherein the pullout apparatus is configured such that the location of the retracted end position of the pullout is adjustable, characterized in that the pullout apparatus comprises a motor-driven adjustment unit to set the location of the retracted end position of the pullout ; and in that the motor-driven adjustment unit comprises a threaded spindle , which has a threaded rod and a spindle nut , and an electric motor driving the threaded spindle , with a traveling of the pullout between the retracted end position and the extended end position taking place on the basis of a corresponding traveling of the spindle nut . characterized in that the pullout apparatus comprises a motor-driven adjustment unit to set the location of the retracted end position of the pullout ; and in that the motor-driven adjustment unit comprises a threaded spindle , which has a threaded rod and a spindle nut , and an electric motor driving the threaded spindle , with a traveling of the pullout between the retracted end position and the extended end position taking place on the basis of a corresponding traveling of the spindle nut .
In-vitro Human nipple skin model characterized in that it comprises keratinocytes of human origin overexpressing filaggrin and in that it comprises a lesion mimicking a crack, in which said keratinocytes constitutively exhibit a level of expression of the filaggrin biological marker greater than a reference level of expression, said reference level of expression corresponding to a level of expression usually observed in primary cultures of keratinocytes of human origin; and in that said model is an epidermis model comprising a matrix support.
A furniture system comprising: a chair including: a seat ; a backrest coupled to the seat ; and a base supporting the backrest and the seat , a plurality of sensors coupled to the chair , each sensor operable to detect a physical force imparted by a user on the chair , and generate an output signal indicative of the physical force; a processor coupled to the plurality of sensors , and the processor operable to: receive the output signals generated by the plurality of sensors; determine, based on at least one of the output signals, a current posture of the user sitting in the chair; and implement enterprise logic to: determine based upon the posture of the user when the user is distracted; send a push notification for encouraging the user to stay on task to the user in response to the determination that the user is distracted; and receive feedback from the user indicating that the enterprise logic improperly determined that the user was distracted. a chair including: a seat ; a backrest coupled to the seat ; and a base supporting the backrest and the seat , a seat ; a backrest coupled to the seat ; and a base supporting the backrest and the seat , a plurality of sensors coupled to the chair , each sensor operable to detect a physical force imparted by a user on the chair , and generate an output signal indicative of the physical force; a processor coupled to the plurality of sensors , and the processor operable to: receive the output signals generated by the plurality of sensors; determine, based on at least one of the output signals, a current posture of the user sitting in the chair; and implement enterprise logic to: determine based upon the posture of the user when the user is distracted; send a push notification for encouraging the user to stay on task to the user in response to the determination that the user is distracted; and receive feedback from the user indicating that the enterprise logic improperly determined that the user was distracted. receive the output signals generated by the plurality of sensors; determine, based on at least one of the output signals, a current posture of the user sitting in the chair; and implement enterprise logic to: determine based upon the posture of the user when the user is distracted; send a push notification for encouraging the user to stay on task to the user in response to the determination that the user is distracted; and receive feedback from the user indicating that the enterprise logic improperly determined that the user was distracted. determine based upon the posture of the user when the user is distracted; send a push notification for encouraging the user to stay on task to the user in response to the determination that the user is distracted; and receive feedback from the user indicating that the enterprise logic improperly determined that the user was distracted.