mhurhangee/patent-ind-claim-en huggingface dataset:
A device for multicolor optical imaging of a sample with wavelength-dependent optical path length enhancement, the device comprising: an optical resonator for enhancing an optical path length; a sample holder for mounting the sample in the optical resonator , wherein the sample holder is configured to hold the sample such that an optical axis of the optical resonator intersects with the sample ; a first imaging system for imaging the sample at a first wavelength with a first imaging technique, wherein the imaging is performed along an outgoing optical axis of the optical resonator ; characterized in that the device further comprises: a second imaging system for imaging the sample at a second wavelength with a second imaging technique, wherein the imaging is performed along an outgoing optical axis of the optical resonator and wherein the second wavelength is different from the first wavelength; wherein: at least one of the first and second imaging techniques is a microscopic imaging technique; and a first finesse of the optical resonator at the first wavelength and a second finesse of the optical resonator at the second wavelength are chosen such that the optical resonator enhances a first image quality indicator of the imaging with the first imaging system and a second image quality indicator of the imaging with the second imaging system . an optical resonator for enhancing an optical path length; a sample holder for mounting the sample in the optical resonator , wherein the sample holder is configured to hold the sample such that an optical axis of the optical resonator intersects with the sample ; a first imaging system for imaging the sample at a first wavelength with a first imaging technique, wherein the imaging is performed along an outgoing optical axis of the optical resonator ; characterized in that the device further comprises: a second imaging system for imaging the sample at a second wavelength with a second imaging technique, wherein the imaging is performed along an outgoing optical axis of the optical resonator and wherein the second wavelength is different from the first wavelength; wherein: at least one of the first and second imaging techniques is a microscopic imaging technique; and a first finesse of the optical resonator at the first wavelength and a second finesse of the optical resonator at the second wavelength are chosen such that the optical resonator enhances a first image quality indicator of the imaging with the first imaging system and a second image quality indicator of the imaging with the second imaging system . at least one of the first and second imaging techniques is a microscopic imaging technique; and a first finesse of the optical resonator at the first wavelength and a second finesse of the optical resonator at the second wavelength are chosen such that the optical resonator enhances a first image quality indicator of the imaging with the first imaging system and a second image quality indicator of the imaging with the second imaging system .
An engineered immune cell comprising a first nucleic acid comprising a nucleotide sequence encoding a chimeric antigen receptor (CAR) and a second nucleic acid comprising a nucleotide sequence encoding an antibody linked to a localizing domain, wherein the antibody binds to: a factor in a CD3/T-cell receptor (TCR) complex selected from the group consisting of CD3ε, TCRα, TCRβ, TCR7, TCRδ, CD3δ, CD37, or CD3ζ; or a receptor that downregulates immune response selected from the group consisting of programmed cell death protein 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), T-cell immunoglobulin and mucin-domain containing-3 (Tim3), killer immunoglobulin-like receptor (KIR) 2DL1, KIR2DL2/DL3, and NKG2A; and wherein the antibody linked to the localizing domain downregulates the cell surface expression of the factor or receptor. wherein the antibody binds to: a factor in a CD3/T-cell receptor (TCR) complex selected from the group consisting of CD3ε, TCRα, TCRβ, TCR7, TCRδ, CD3δ, CD37, or CD3ζ; or a receptor that downregulates immune response selected from the group consisting of programmed cell death protein 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), T-cell immunoglobulin and mucin-domain containing-3 (Tim3), killer immunoglobulin-like receptor (KIR) 2DL1, KIR2DL2/DL3, and NKG2A; and a factor in a CD3/T-cell receptor (TCR) complex selected from the group consisting of CD3ε, TCRα, TCRβ, TCR7, TCRδ, CD3δ, CD37, or CD3ζ; or a receptor that downregulates immune response selected from the group consisting of programmed cell death protein 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), T-cell immunoglobulin and mucin-domain containing-3 (Tim3), killer immunoglobulin-like receptor (KIR) 2DL1, KIR2DL2/DL3, and NKG2A; and wherein the antibody linked to the localizing domain downregulates the cell surface expression of the factor or receptor.
An electrochemical method for producing a diene comprising: obtaining an alkali metal salt of a carboxylic acid that has at least one OH functional group in addition to the carboxylic acid moiety; wherein the OH functional group is in the alpha position with respect to the carboxylic acid moiety; electrochemically decarboxylating the alkali metal salt of the carboxylic acid into alkyl radicals that react to form a coupled radical product, wherein the coupled radical product is a diol; and dehydrating the diol to form a diene. obtaining an alkali metal salt of a carboxylic acid that has at least one OH functional group in addition to the carboxylic acid moiety; wherein the OH functional group is in the alpha position with respect to the carboxylic acid moiety; electrochemically decarboxylating the alkali metal salt of the carboxylic acid into alkyl radicals that react to form a coupled radical product, wherein the coupled radical product is a diol; and dehydrating the diol to form a diene.
Process for manufacturing a cast metal heat exchanger housing for a vehicle heater with a pot-like housing wall elongated in the direction of a housing longitudinal axis (L) and with a plurality of heat transfer ribs extending in the direction of the housing longitudinal axis (L) on an outer side of the housing wall in the area of a circumferential wall and in the area of a bottom wall of the housing wall , the process comprising the following steps: - in a metal casting operation filling liquid metal material into a casting mould via a sprue opening with a sprue cross-sectional area provided in a casting mould in an area near the bottom wall, - after carrying out the metal casting operation, cooling the metal material, - after cooling the metal material, cutting off a sprue from the heat exchanger housing in such a way that that an axial end face of the heat exchanger housing corresponding to the sprue cross-sectional area and essentially at right angles to the housing longitudinal axis (L) is formed, characterized in that the sprue cross-sectional area comprises at least part of the heat transfer ribs and in that the axial end face of the heat exchanger housing corresponding to the sprue cross-sectional area and essentially at right angles to the housing longitudinal axis (L) extends at least into the area of part of the heat transfer ribs . - in a metal casting operation filling liquid metal material into a casting mould via a sprue opening with a sprue cross-sectional area provided in a casting mould in an area near the bottom wall, - after carrying out the metal casting operation, cooling the metal material, - after cooling the metal material, cutting off a sprue from the heat exchanger housing in such a way that that an axial end face of the heat exchanger housing corresponding to the sprue cross-sectional area and essentially at right angles to the housing longitudinal axis (L) is formed,
An apparatus comprising: a video baton for insertion into a plurality of laryngoscope blade covers having different sizes and geometries, wherein the video baton comprises: a handle portion , a shuttle assembly slidingly positioned within the handle portion between an extended position and a retracted position; a flexible coupling element having a proximal end and a distal end, wherein the flexible coupling element is coupled to the shuttle assembly at the proximal end; and an image capturing and lighting assembly positioned at the distal end of the flexible coupling element . a video baton for insertion into a plurality of laryngoscope blade covers having different sizes and geometries, wherein the video baton comprises: a handle portion , a shuttle assembly slidingly positioned within the handle portion between an extended position and a retracted position; a flexible coupling element having a proximal end and a distal end, wherein the flexible coupling element is coupled to the shuttle assembly at the proximal end; and an image capturing and lighting assembly positioned at the distal end of the flexible coupling element . a handle portion , a shuttle assembly slidingly positioned within the handle portion between an extended position and a retracted position; a flexible coupling element having a proximal end and a distal end, wherein the flexible coupling element is coupled to the shuttle assembly at the proximal end; and an image capturing and lighting assembly positioned at the distal end of the flexible coupling element .
An icemaking system comprising a refrigerant circuit configured to execute a vapor compression refrigeration cycle, a circulation circuit for solution as a cooling target of the refrigerant circuit , and a control device configured to control refrigerant evaporation temperature at the refrigerant circuit , wherein the circulation circuit includes a solution flow path of an ice generator , a solution tank used to store the solution, and a pump configured to pressure feed the solution to the solution flow path , the refrigerant circuit includes an evaporator of the ice generator , a compressor , a condenser , and an expansion valve , characterized in that the control device includes a control unit configured to calculate a target evaporation temperature in accordance with a correlation between the solute concentration and the refrigerant evaporation temperature, the correlation being defined such that a temperature difference between a freezing temperature of the solution and the refrigerant evaporation temperature increases as the solute concentration increases and an icemaking amount increases as the solution has higher solute concentration, adjust the evaporation temperature at the evaporator to reach the target evaporation temperature thus calculated, and adjust to lower evaporation temperature at the evaporator as the solution has higher solute concentration. the circulation circuit includes a solution flow path of an ice generator , a solution tank used to store the solution, and a pump configured to pressure feed the solution to the solution flow path , the refrigerant circuit includes an evaporator of the ice generator , a compressor , a condenser , and an expansion valve , characterized in that the control device includes a control unit configured to calculate a target evaporation temperature in accordance with a correlation between the solute concentration and the refrigerant evaporation temperature, the correlation being defined such that a temperature difference between a freezing temperature of the solution and the refrigerant evaporation temperature increases as the solute concentration increases and an icemaking amount increases as the solution has higher solute concentration, adjust the evaporation temperature at the evaporator to reach the target evaporation temperature thus calculated, and adjust to lower evaporation temperature at the evaporator as the solution has higher solute concentration.
A shock absorbing grip assembly comprising: a) one or more slotted grip end clamps ; b) one or more cavities in said slotted grip end clamps; c) a grip sleeve , wherein said grip sleeve includes one or more protruding engagement members , and further one or more elastomeric isolator inserts housed within each of said one or more cavities in said grip end clamps and wherein said one or more protruding engagement members mates within said cavities in said slotted grip end clamps interacting with said one or more elastomeric isolator inserts; and d) an outer grip ; whereby said one or more grip end clamps suspends or suspend said grip sleeve from contact with a handle or handlebar , said grip sleeve having torsional, rotational, linear and axial shock absorbing capacity when mounted to a handle or handlebar. a) one or more slotted grip end clamps ; b) one or more cavities in said slotted grip end clamps; c) a grip sleeve , wherein said grip sleeve includes one or more protruding engagement members , and further one or more elastomeric isolator inserts housed within each of said one or more cavities in said grip end clamps and wherein said one or more protruding engagement members mates within said cavities in said slotted grip end clamps interacting with said one or more elastomeric isolator inserts; and d) an outer grip ; whereby said one or more grip end clamps suspends or suspend said grip sleeve from contact with a handle or handlebar , said grip sleeve having torsional, rotational, linear and axial shock absorbing capacity when mounted to a handle or handlebar.
A method for transferring at least one chip , from a first support to a second support , comprising: - while the chip is integral with the first support , a formation of an intermediate layer in the liquid state between, and in contact with, a front face of the chip and an assembly surface of a face of the second support , and a solidification of the intermediate layer - then, a detachment of the chip from the first support while maintaining the intermediate layer in the solid state, and wherein the solidification comprises placing the assembly surface of the face of the second support at a temperature lower than a solidification temperature of the intermediate layer , and characterised in that the formation of the intermediate layer comprises forming a liquid coating intended to form the intermediate layer on the front face of the chip , then bringing together the first support and the second support so as to contact the liquid coating with the assembly surface of the face of the second support , and placing the assembly surface of the face of the second support at a temperature lower than a solidification temperature of the intermediate layer is carried out before contacting the liquid coating with the assembly surface of the face of the second support . - while the chip is integral with the first support , a formation of an intermediate layer in the liquid state between, and in contact with, a front face of the chip and an assembly surface of a face of the second support , and a solidification of the intermediate layer - then, a detachment of the chip from the first support while maintaining the intermediate layer in the solid state, and wherein the solidification comprises placing the assembly surface of the face of the second support at a temperature lower than a solidification temperature of the intermediate layer , and characterised in that the formation of the intermediate layer comprises forming a liquid coating intended to form the intermediate layer on the front face of the chip , then bringing together the first support and the second support so as to contact the liquid coating with the assembly surface of the face of the second support , and placing the assembly surface of the face of the second support at a temperature lower than a solidification temperature of the intermediate layer is carried out before contacting the liquid coating with the assembly surface of the face of the second support .
A composition for use in a method of extracting a tooth in a subject in need thereof, the composition comprising collagenase as destructing agent of the periodontal ligament surrounding the tooth, wherein the collagenase is contacted with at least one locus at the periodontal ligament space surrounding the tooth.
A sample analyzing apparatus , comprising: an apparatus housing ; a sample carrier disposed in the apparatus housing and configured for supporting a sample ; a reagent reservoir ; a pump communicating with the reagent reservoir ; an injector assembly disposed in the apparatus housing and comprising an injector needle configured for communicating with the reagent reservoir via the pump ; and a luminescence detector positioned in the apparatus housing to receive optical signals from the sample , wherein the injector assembly comprises an injector housing , wherein the injector needle extends through the injector housing , the injector housing comprises a distal housing end , characterized in that the injector needle comprises a needle outlet at the distal housing end, and the injector assembly comprises a liquid sensor disposed in the injector housing and configured for detecting the presence of liquid at the housing end . an apparatus housing ; a sample carrier disposed in the apparatus housing and configured for supporting a sample ; a reagent reservoir ; a pump communicating with the reagent reservoir ; an injector assembly disposed in the apparatus housing and comprising an injector needle configured for communicating with the reagent reservoir via the pump ; and a luminescence detector positioned in the apparatus housing to receive optical signals from the sample , wherein the injector assembly comprises an injector housing , wherein the injector needle extends through the injector housing , the injector housing comprises a distal housing end , characterized in that the injector needle comprises a needle outlet at the distal housing end, and the injector assembly comprises a liquid sensor disposed in the injector housing and configured for detecting the presence of liquid at the housing end .
Voice control method, in particular for controlling a personal computer, a smartphone, an on-board computer of a vehicle or other apparatuses, in which it is determined whether a control request can be determined from spoken language recorded using a recording device and processed using a voice recognition device , a voice control device being operated using software which can be changed by means of at least one piece of expansion software (24-24n) which is provided for downloading from a server , the voice control device comprising a device for changing the software, which device , if it has been determined that the voice control device is not set up to determine and process the control request, checks whether the voice control device can be set up to determine and process the control request by means of the expansion software (24-24n), characterized in that the software is changed by means of the expansion software (24-24n) in such a manner that the software can be used to access information which could previously not be called up from the Internet by virtue of an interface for making contact with an information service of the Internet being implemented in the software and the software being updated in such a manner that it can process the information which can be newly retrieved from the Internet via the interface.
Motor vehicle component, in particular sill, comprising a first profile and a second profile , wherein the first profile and the second profile each have a bonding surface , wherein the first and the second profile are adhesively bonded together at their bonding surfaces by an adhesive , characterized in that the bonding surface of the first profile and/or the bonding surface of the second profile has at least one groove , wherein the adhesive covers the bonding surface completely in those regions in which a groove has not been formed and does not cover the bonding surface in those regions in which a groove has been formed.
A surgical stapling apparatus , comprising: a cartridge assembly defining a tissue contacting surface and a longitudinally extending elongate slot ; an anvil assembly defining a tissue contacting surface and a longitudinally extending elongate slot ; a surgical buttress (B) releasably secured to at least one of the tissue contacting surface of the cartridge assembly and the tissue contacting surface of the anvil assembly by at least one anchor (S); a central knife blade slidably disposable in the longitudinally extending elongate slot of the cartridge assembly and the anvil assembly ; and a distal knife blade supported in a distal end portion of at least one of the cartridge assembly and/or a distal knife blade supported in a distal end portion of the anvil assembly , wherein the distal knife blade of the cartridge assembly and/or the distal knife blade of the anvil assembly is/are actuatable by the central knife blade , upon an actuation of the central knife blade and firing of the surgical stapling apparatus , to sever a respective distal anchor (S); characterised in that the distal knife blade of the cartridge assembly and/or the distal knife blade of the anvil assembly define/s a concave distal knife edge . a cartridge assembly defining a tissue contacting surface and a longitudinally extending elongate slot ; an anvil assembly defining a tissue contacting surface and a longitudinally extending elongate slot ; a surgical buttress (B) releasably secured to at least one of the tissue contacting surface of the cartridge assembly and the tissue contacting surface of the anvil assembly by at least one anchor (S); a central knife blade slidably disposable in the longitudinally extending elongate slot of the cartridge assembly and the anvil assembly ; and a distal knife blade supported in a distal end portion of at least one of the cartridge assembly and/or a distal knife blade supported in a distal end portion of the anvil assembly , wherein the distal knife blade of the cartridge assembly and/or the distal knife blade of the anvil assembly is/are actuatable by the central knife blade , upon an actuation of the central knife blade and firing of the surgical stapling apparatus , to sever a respective distal anchor (S); characterised in that the distal knife blade of the cartridge assembly and/or the distal knife blade of the anvil assembly define/s a concave distal knife edge .