mhurhangee/patent-ind-claim-en huggingface dataset:
An orthopedic device having a foot part , a lower-leg part and a thigh part , the foot part being connected by an ankle joint to the lower-leg part so as to be pivotable about a first pivot axis , the lower-leg part being connected by a knee joint to the thigh part so as to be pivotable about a second pivot axis , the foot part being connected to the thigh part by a force-transmitting mechanism , whereas the force-transmitting mechanism causes a dorsiflexion of the foot part in the event of a knee flexion over a first knee flexion angle range, characterized in that in the event of further knee flexion after a knee flexion limit angle (α Lim ) has been exceeded, the force-transmitting mechanism causes a plantar flexion of the foot part , whereas the knee flexion limit angle (α Lim ) is between 50° and 80°.
Material web working/processing arrangement, in particular material web dispensing arrangement, in particular material web unrolling arrangement, in particular material web splicing arrangement, a) having at least one release liner removal apparatus comprising i) at least one release liner removal device for removing at least one release liner from at least one adhesive piece arranged on a material web , ii) at least one support body which supports the at least one release liner removal device , and iii) at least one guide body which is arranged adjacent to the at least one release liner removal device at least during the removal of the at least one release liner and which serves for guiding the material web , characterized in that b) at least one guide for guiding at least one material web holding device (78; 78a) from at least one material web drawing-in point to at least one material web transfer point for the preparation of a material web to be worked/processed runs at least between the at least one material web drawing-in point and a preparation device of the material web working/processing arrangement. a) having at least one release liner removal apparatus comprising i) at least one release liner removal device for removing at least one release liner from at least one adhesive piece arranged on a material web , ii) at least one support body which supports the at least one release liner removal device , and iii) at least one guide body which is arranged adjacent to the at least one release liner removal device at least during the removal of the at least one release liner and which serves for guiding the material web , characterized in that i) at least one release liner removal device for removing at least one release liner from at least one adhesive piece arranged on a material web , ii) at least one support body which supports the at least one release liner removal device , and iii) at least one guide body which is arranged adjacent to the at least one release liner removal device at least during the removal of the at least one release liner and which serves for guiding the material web , b) at least one guide for guiding at least one material web holding device (78; 78a) from at least one material web drawing-in point to at least one material web transfer point for the preparation of a material web to be worked/processed runs at least between the at least one material web drawing-in point and a preparation device of the material web working/processing arrangement.
A Factor VIII composition for use in treating a patient by reconstituting a lyophilised Factor VIII composition in a volume of a diluent to prepare a reconstituted Factor VIII composition and administering the reconstituted Factor VIII composition to the patient, wherein the lyophilised Factor VIII composition is obtainable by lyophilizing a volume of a liquid Factor VIII composition formulated without adding albumin to said composition, wherein the liquid Factor VIII composition comprises the following formulation excipients in addition to Factor VIII: 4% to 10% of a bulking agent selected from the group consisting of mannitol, glycine and alanine; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; 100 mM to 300 mM NaCl; and a buffering agent for maintaining a pH of approximately between 6 and 8; and wherein the volume of the diluent is equal to or greater than the volume of the liquid Factor VIII composition. 4% to 10% of a bulking agent selected from the group consisting of mannitol, glycine and alanine; 1% to 4% of a stabilizing agent selected from the group consisting of sucrose, trehalose, raffinose, and arginine; 1 mM to 5 mM calcium salt; 100 mM to 300 mM NaCl; and a buffering agent for maintaining a pH of approximately between 6 and 8; and wherein the volume of the diluent is equal to or greater than the volume of the liquid Factor VIII composition.
Conveyance element for a people conveyor , wherein the conveyance element is configured for being moved in a conveyance direction; wherein the conveyance element comprises a tread plate configured for supporting passengers, the tread plate having a longitudinal extension extending parallel to the conveyance direction and a lateral extension extending transversely to the conveyance direction; wherein the conveyance element further comprises at least one protection element configured for collecting items and/or fluids; wherein the at least one protection element extends beyond at least one end of the tread plate in the conveyance direction and is arranged below the tread plate , when the conveyance element is arranged in an upright orientation characterized in that the at least one protection element comprises a front end facing away from the conveyance element with a sealing lip provided at said front end . wherein the conveyance element is configured for being moved in a conveyance direction; wherein the conveyance element comprises a tread plate configured for supporting passengers, the tread plate having a longitudinal extension extending parallel to the conveyance direction and a lateral extension extending transversely to the conveyance direction; wherein the conveyance element further comprises at least one protection element configured for collecting items and/or fluids; wherein the at least one protection element extends beyond at least one end of the tread plate in the conveyance direction and is arranged below the tread plate , when the conveyance element is arranged in an upright orientation characterized in that the at least one protection element comprises a front end facing away from the conveyance element with a sealing lip provided at said front end .
Solution for intravenous infusion containing: curcumin and/or one or more curcumin derivatives, namely demethoxycurcumin and/or bisdemethoxycurcumin, dimethyl sulfoxide, one or more solubilizers, sodium selenite, and a buffer in an aqueous infusion medium. curcumin and/or one or more curcumin derivatives, namely demethoxycurcumin and/or bisdemethoxycurcumin, dimethyl sulfoxide, one or more solubilizers, sodium selenite, and a buffer in an aqueous infusion medium.
Neural tissue unit forming a neural cell cluster for use in cell therapy for implantation in the nervous system of a human or non-human mammal, the neural tissue unit being capable of projecting axons within the host tissue, wherein said neural tissue unit contains differentiated post-mitotic neuronal cells which are immuno-compatible with the mammal intended to receive the neural tissue unit and of which the phenotype corresponds to the phenotype of the defective cells to be replaced, and which are organized into a three-dimensional array and embedded in an extracellular matrix layer, said unit being obtained from a cellular microcompartment comprising a hydrogel capsule surrounding a single neural tissue unit, and said hydrogel capsule being at least partially removed prior to use of said neural tissue unit.
An application execution program for causing a computer to execute a process of executing an application stored in a memory in a terminal device , the process comprising: downloading (S2) the application and data of the application from an application server and storing (S4) the application and the data in the memory of the terminal device , in an online state in which the terminal device is able to communicate with an application server ; associating (S6) an external address outside of the terminal device with the application stored in the memory in the terminal device ; performing an initialization process (S12) of securing a data storage region associated with the external address in the terminal device; booting (S17) an internal web server to which the external address is assigned, the internal web server being formed in the terminal device ; causing (S19, S20) a browser to access the internal web server at the external address and acquire the application stored in the memory, in an offline state in which the terminal device is unable to communicate with the application server; causing (S21) the browser to execute the application and access data in the data storage region in the terminal device associated with the external address, in the offline state; and writing data (S13) with respect to the application stored in the memory, into the data storage region, after the initialization process (S12). downloading (S2) the application and data of the application from an application server and storing (S4) the application and the data in the memory of the terminal device , in an online state in which the terminal device is able to communicate with an application server ; associating (S6) an external address outside of the terminal device with the application stored in the memory in the terminal device ; performing an initialization process (S12) of securing a data storage region associated with the external address in the terminal device; booting (S17) an internal web server to which the external address is assigned, the internal web server being formed in the terminal device ; causing (S19, S20) a browser to access the internal web server at the external address and acquire the application stored in the memory, in an offline state in which the terminal device is unable to communicate with the application server; causing (S21) the browser to execute the application and access data in the data storage region in the terminal device associated with the external address, in the offline state; and writing data (S13) with respect to the application stored in the memory, into the data storage region, after the initialization process (S12).
A thin-film transistor, comprising a gate (110; 110'), a gate insulation layer (120; 120') and an active layer (130; 130') stacked on a substrate , the active layer (130; 130') being formed therein with a source region, a drain region and a channel region, the surface of the active layer (130; 130') facing the gate insulation layer (120; 120') is at least partially formed with a non-planar surface in the channel region, such that the non-planar surface of the active layer (130; 130') has a tortuous shape in a width direction of the channel region, and that the active layer (130; 130') has a constant thickness in the channel region, wherein the width direction of the channel region is a direction perpendicular to a length direction of the channel region in a plane parallel to a surface of the substrate , and the length direction of the channel region is a direction from the source region to the drain region.
A method for preparing a cellulose reactive functionalized polyvinylamide adduct comprising reacting a substantially aqueous reaction mixture of a vinylamide polymer and a cellulose reactive agent to form the adduct, wherein the concentration of the vinylamide polymer is below, equal to or no more than 1 % above a Critical Concentration and the Critical Concentration is defined as the concentration of the vinylamide polymer above which Critical Concentration the viscosity increases for the reaction mixture resulting from the forward progress of the adduct formation, and below which Critical Concentration, the viscosity decreases for the reaction mixture resulting from the forward progress of adduct formation, wherein the vinylamide polymer is cationic.
A targeting set for use with positioning a biopsy device within a patient, the targeting set comprising: (a) a stylet ; and (b) a cannula configured to coaxially receive the stylet; and (c) an actuator , wherein the actuator includes: (i) a housing , (ii) a lock array extending inwardly within a hollow interior defined by the housing, wherein the stylet is configured for insertion into the housing of the actuator such that at least a portion of the stylet engages the lock array, wherein the lock array is configured to selectively lock the stylet in a plurality of axial positions relative to the housing, characterized in that the stylet is configured to move the cannula as the stylet moves to an axial position relative to the housing. (a) a stylet ; and (b) a cannula configured to coaxially receive the stylet; and (c) an actuator , wherein the actuator includes: (i) a housing , (ii) a lock array extending inwardly within a hollow interior defined by the housing, wherein the stylet is configured for insertion into the housing of the actuator such that at least a portion of the stylet engages the lock array, wherein the lock array is configured to selectively lock the stylet in a plurality of axial positions relative to the housing, characterized in that the stylet is configured to move the cannula as the stylet moves to an axial position relative to the housing. (i) a housing , (ii) a lock array extending inwardly within a hollow interior defined by the housing, wherein the stylet is configured for insertion into the housing of the actuator such that at least a portion of the stylet engages the lock array, wherein the lock array is configured to selectively lock the stylet in a plurality of axial positions relative to the housing, characterized in that the stylet is configured to move the cannula as the stylet moves to an axial position relative to the housing.
Rowing boat comprising a hull , at least one footrest for a rower's feet, at least one outrigger for at least one oar, said outrigger being rigidly connected to said footrest , at least one seat for said rower, characterized in that it further comprises at least one first guide element (201, 202; 801, 802, 805, 806; 805b, 905, 900) adapted to allow free translation of said footrest and of said outrigger in a direction parallel to the advancement of said boat while rowing, and in that it further comprises at least one second guide element (203, 204; 807) adapted to allow said seat to translate in said direction while rowing, and at least one elastic element that connects said seat to said hull , said elastic element being configured to exert a pulling force for the propulsion of said hull , said pulling force transferring energy accumulated by the thrust imparted by said rower.
An electrochemical sensor for determining at least one physical and/or chemical parameter of a measuring medium, with said sensor comprising a sensor head , a sensor chip with a sensitive region , a sensor body with an end piece , a sealing member , and a press-on element ; wherein the sensor body is connected to the sensor head ; wherein the end piece is a hollow body with a closed end region and a measuring opening , by means of which, during operation, a measuring medium makes contact with the sensitive region of the sensor chip , which is arranged in the interior of the hollow body; wherein the sealing member encloses the measuring opening , excluding the sensitive region of the sensor chip , and the interior of the end piece seals off the measuring medium during operation; wherein the press-on element presses the sensor chip against the sealing member and the edge of the measuring opening ; wherein the end piece is designed as a single piece and is free of gaps in the region making contact with the measuring medium during operation; and the sensor further comprises a chip carrier , on which the sensor chip is arranged during operation; characterized in that the chip carrier further comprises a fixing element for the sealing member in order to the fix the position of the chip carrier , of the sensor chip , and of the sealing member in relation to one another.
A device for electroporating and delivering one or more antigens, the device comprising: a housing having a tip portion ; a plurality of electrode arrays each coupled to the tip portion , wherein the electrode arrays project from the tip portion and define spatially separate sites, each electrode array includes a plurality of electrodes , and the tip portion is detachable from the device for sterilization between uses of the device ; a pulse generator electrically coupled to at least one electrode of each electrode array ; and a programmable microcontroller electrically coupled to the pulse generator , wherein each electrode is configured to deliver an electroporating pulse to cells of epidermal tissues, and wherein the microcontroller is configured to adjust parameters of the electroporating pulse of each electrode array independently. a housing having a tip portion ; a plurality of electrode arrays each coupled to the tip portion , wherein the electrode arrays project from the tip portion and define spatially separate sites, each electrode array includes a plurality of electrodes , and the tip portion is detachable from the device for sterilization between uses of the device ; a pulse generator electrically coupled to at least one electrode of each electrode array ; and a programmable microcontroller electrically coupled to the pulse generator , wherein each electrode is configured to deliver an electroporating pulse to cells of epidermal tissues, and wherein the microcontroller is configured to adjust parameters of the electroporating pulse of each electrode array independently.
An apparatus comprising: a first channel configured to: receive heated air from an electrical component; and deflect the heated air from a posterior electrical component, the deflection caused by a curvature of an internal partition ; and a second channel , segmented from the first channel via the internal partition , configured to provide cool air to the posterior electrical component, characterised in that the first channel and the second channel form a double channel helix. a first channel configured to: receive heated air from an electrical component; and deflect the heated air from a posterior electrical component, the deflection caused by a curvature of an internal partition ; and receive heated air from an electrical component; and deflect the heated air from a posterior electrical component, the deflection caused by a curvature of an internal partition ; and a second channel , segmented from the first channel via the internal partition , configured to provide cool air to the posterior electrical component, characterised in that the first channel and the second channel form a double channel helix.
Filter module for separating in particular sticky and dry paint and/or adhesive overspray, abrasive dusts etc., with a filter arrangement in a filter housing in the form of an inlay for receiving a filter medium , said inlay consisting of a plurality of sections (10-13), wherein pivotable spacer plates (3-7) are integrated in the inlay sections (10-13), which, in a swiveled-out position, are positioned at least approximately at right angles with the plane of the inlay section (10-13), characterized in that two spacer plates arranged side by side and wedged together are provided between an inlay section and the housing wall of the filter housing .
A method comprising: (a) in a sample comprising nucleic acids from a cancer cell of a subject, selectively enriching for one or more nucleic acids comprising EGFR nucleotide sequences, to produce an enriched sample; (b) sequencing the one or more nucleic acids comprising EGFR nucleotide sequences from the enriched sample to produce sequence reads; (c) determining, among the sequence reads, a presence or an absence of at least one EGFR nucleotide sequence variant encoding an amino acid or codon sequence variant selected from the group consisting of G465V, D1083N, I491R, K467I, and K1061T, wherein numbering corresponds to the EGFR amino acid sequence in NCBI Accession Number NP_005219.2; and (d) classifying the subject as having a cancer un-responsive to cetuximab therapy when the presence of at least one of the EGFR nucleotide sequence variants is detected. (a) in a sample comprising nucleic acids from a cancer cell of a subject, selectively enriching for one or more nucleic acids comprising EGFR nucleotide sequences, to produce an enriched sample; (b) sequencing the one or more nucleic acids comprising EGFR nucleotide sequences from the enriched sample to produce sequence reads; (c) determining, among the sequence reads, a presence or an absence of at least one EGFR nucleotide sequence variant encoding an amino acid or codon sequence variant selected from the group consisting of G465V, D1083N, I491R, K467I, and K1061T, wherein numbering corresponds to the EGFR amino acid sequence in NCBI Accession Number NP_005219.2; and (d) classifying the subject as having a cancer un-responsive to cetuximab therapy when the presence of at least one of the EGFR nucleotide sequence variants is detected.
Device for switchably influencing electromagnetic radiation, comprising: - a phase change material being switchable between at least a first state and a second state, the first state and the second state having different electrical and/or magnetic properties; - an optically responsive structure in contact with the phase change material , the optically responsive structure having - at least a first nanostructure and a second nanostructure , - the first nanostructure being different from the second nanostructure ; - the first nanostructure being optically responsive at a predetermined electromagnetic wavelength when the phase change material is in its first state, and non-responsive at the same predetermined wavelength when the phase change material is in its second state, and - the second nanostructure being optically responsive at the same predetermined electromagnetic wavelength when the phase change material is in its second state, and non-responsive at the same predetermined wavelength when the phase change material is in its first state. - a phase change material being switchable between at least a first state and a second state, the first state and the second state having different electrical and/or magnetic properties; - an optically responsive structure in contact with the phase change material , the optically responsive structure having - at least a first nanostructure and a second nanostructure , - the first nanostructure being different from the second nanostructure ; - at least a first nanostructure and a second nanostructure , - the first nanostructure being different from the second nanostructure ; - the first nanostructure being optically responsive at a predetermined electromagnetic wavelength when the phase change material is in its first state, and non-responsive at the same predetermined wavelength when the phase change material is in its second state, and - the second nanostructure being optically responsive at the same predetermined electromagnetic wavelength when the phase change material is in its second state, and non-responsive at the same predetermined wavelength when the phase change material is in its first state.
Bicycle comprising a bicycle wheel axle in the form of a tube made of metal or carbon fibre-reinforced composite material wherein the axle has on its circumference at both ends identical seating nests, which comprise a circular narrowing forming a V-shaped groove which are positioned according to a pair of fork legs and wherein each narrowing has at least a pair of slanting surfaces that are convergent inwards, while an outer contour of the section of an axle's wall , parallel to a symmetry plane of a wheel, which goes through the slanting surfaces has a non-circular shape, preferably the shape of a regular polygon or an irregular polygon or the shape of an irregular closed curve.