A compound according to formula IA: stereoisomers, and/or salts thereof; wherein LisN; Z is a substituted or unsubstituted C 1 -C 4 alkylene; Wis Xis D is N or CR 9 ; one of G 1 , G 2 , G 3 , and G 4 is CR 13 , one of G 1 , G 2 , G 3 , and G 4 is C bonded to R 4 , and the others are selected from the group consisting of CH and CR 11 ; Q is O, S, or NR 12 ; R 1 and R 2 are independently H, OH, halo, CN, carboxyl, NR a R b , or a substituted or unsubstituted alkyl, alkoxy, or hydroxyalkyl group; R 3 is a substituted or unsubstituted alkyl or cycloalkyl group; R 4 is CN, SO 3 H, CONR a R b , SO 2 NR a R b , NHSO 2 R b , SO 2 NHCOR a , CO 2 R c , or a substituted or unsubstituted tetrazolyl or 1,2,4-oxadiazol-5 -one-3-yl group; R 9 and R 13 are independently H, halo, or a substituted or unsubstituted C 1 -C 6 alkyl, or O-(C 1 -C 6 alkyl) group; R 10 at each occurrence is independently halo, CO 2 R c , or a substituted or unsubstituted alkyl, alkoxy, hydroxyalkyl, cycloalkyl, or fluorinated cycloalkyl group; R 11 at each occurrence are independently OH, halo, CF 3 , CN, carboxyl, NR a R b , or a substituted or unsubstituted alkyl, alkoxy group, or phenyl group; R 12 is H or a substituted or unsubstituted C 1 -C 6 alkyl group; and R a at each occurrence is independently H, or a substituted or unsubstituted alkyl, haloalkyl, cycloalkyl, aryl, or SO 2 -alkyl group; R b at each occurrence is H or a substituted or unsubstituted alkyl, or haloalkyl group; R c is H or a substituted or unsubstituted alkyl, alkenyl, alkynyl, or cycloalkyl group; n is 1, 2, 3, or 4; and r and t are each independently 1, 2, or 3. stereoisomers, and/or salts thereof; wherein LisN; Z is a substituted or unsubstituted C 1 -C 4 alkylene; Xis D is N or CR 9 ; one of G 1 , G 2 , G 3 , and G 4 is CR 13 , one of G 1 , G 2 , G 3 , and G 4 is C bonded to R 4 , and the others are selected from the group consisting of CH and CR 11 ; Q is O, S, or NR 12 ; R 1 and R 2 are independently H, OH, halo, CN, carboxyl, NR a R b , or a substituted or unsubstituted alkyl, alkoxy, or hydroxyalkyl group; R 3 is a substituted or unsubstituted alkyl or cycloalkyl group; R 4 is CN, SO 3 H, CONR a R b , SO 2 NR a R b , NHSO 2 R b , SO 2 NHCOR a , CO 2 R c , or a substituted or unsubstituted tetrazolyl or 1,2,4-oxadiazol-5 -one-3-yl group; R 9 and R 13 are independently H, halo, or a substituted or unsubstituted C 1 -C 6 alkyl, or O-(C 1 -C 6 alkyl) group; R 10 at each occurrence is independently halo, CO 2 R c , or a substituted or unsubstituted alkyl, alkoxy, hydroxyalkyl, cycloalkyl, or fluorinated cycloalkyl group; R 11 at each occurrence are independently OH, halo, CF 3 , CN, carboxyl, NR a R b , or a substituted or unsubstituted alkyl, alkoxy group, or phenyl group; R 12 is H or a substituted or unsubstituted C 1 -C 6 alkyl group; and R a at each occurrence is independently H, or a substituted or unsubstituted alkyl, haloalkyl, cycloalkyl, aryl, or SO 2 -alkyl group; R b at each occurrence is H or a substituted or unsubstituted alkyl, or haloalkyl group; R c is H or a substituted or unsubstituted alkyl, alkenyl, alkynyl, or cycloalkyl group; n is 1, 2, 3, or 4; and r and t are each independently 1, 2, or 3. <EOS>