A microdermabrasion device for treating a skin surface, comprising: a handpiece assembly having a distal end and a proximal end, said handpiece assembly comprising at least one delivery conduit and at least one waste conduit ; a tip configured to be positioned along the distal end of the handpiece assembly , said tip being configured to contact the skin surface; a flow control device or feature (F) included within the handpiece assembly to regulate the flow of fluids through the at least one delivery conduit ; wherein the tip comprises a lip , a first opening in fluid communication with the at least one fluid delivery conduit and a second opening in fluid communication with the at least one waste conduit ; at least one abrasive element positioned along a distal end of the tip, said abrasive element being configured to selectively remove skin as the tip is moved relative to a skin surface; and at least one time-release material disposed along at least a portion of the tip, wherein the at least one time-release material is configured to be released to a skin surface when fluids are delivered to the tip via the at least one fluid delivery conduit , wherein the at least one time-release material is configured to become available to the skin surface after a particular time period after initiation of a treatment procedure using the device; wherein the first opening , the second opening and the at least one abrasive element of the tip are positioned within an interior of an outer periphery formed by the lip ; wherein the at least one waste conduit is in fluid communication with a vacuum source to selectively remove debris away from the tip ; and wherein the at least one delivery conduit is in fluid communication with the at least one waste conduit and the vacuum source when the lip contacts a skin surface. a handpiece assembly having a distal end and a proximal end, said handpiece assembly comprising at least one delivery conduit and at least one waste conduit ; a tip configured to be positioned along the distal end of the handpiece assembly , said tip being configured to contact the skin surface; a flow control device or feature (F) included within the handpiece assembly to regulate the flow of fluids through the at least one delivery conduit ; wherein the tip comprises a lip , a first opening in fluid communication with the at least one fluid delivery conduit and a second opening in fluid communication with the at least one waste conduit ; at least one abrasive element positioned along a distal end of the tip, said abrasive element being configured to selectively remove skin as the tip is moved relative to a skin surface; and at least one time-release material disposed along at least a portion of the tip, wherein the at least one time-release material is configured to be released to a skin surface when fluids are delivered to the tip via the at least one fluid delivery conduit , wherein the at least one time-release material is configured to become available to the skin surface after a particular time period after initiation of a treatment procedure using the device; wherein the first opening , the second opening and the at least one abrasive element of the tip are positioned within an interior of an outer periphery formed by the lip ; wherein the at least one waste conduit is in fluid communication with a vacuum source to selectively remove debris away from the tip ; and wherein the at least one delivery conduit is in fluid communication with the at least one waste conduit and the vacuum source when the lip contacts a skin surface. <EOS>