mhurhangee/patent-ind-claim-en huggingface dataset:
A method of identifying structures of a therapeutic protein that affect an interaction between the therapeutic protein and a target, wherein the therapeutic protein comprises an antigen-binding portion of an antibody and the target comprises an antigen for the antibody, said method comprising: a. applying a stress to a first sample comprising therapeutic proteins; b. contacting the first sample with a second sample comprising targets to form a mixture comprising (i) therapeutic protein-target complexes, (ii) unbound therapeutic proteins, and (iii) unbound targets; separating the mixture into at least two fractions, wherein an unbound fraction comprises unbound therapeutic proteins and a bound fraction comprises therapeutic protein-target complexes; c. for each of the unbound fraction and bound fraction, identifying and quantifying the abundance of a structure present on a species of the therapeutic protein, wherein the structure comprises an attribute of the therapeutic protein and, when the abundance of a structure in the unbound fraction is greater than the abundance of the structure in the bound fraction, the structure negatively affects the interaction between the therapeutic protein and the target, wherein the attribute forms as a result of a chemical modification that changes the structure of an amino acid. a. applying a stress to a first sample comprising therapeutic proteins; b. contacting the first sample with a second sample comprising targets to form a mixture comprising (i) therapeutic protein-target complexes, (ii) unbound therapeutic proteins, and (iii) unbound targets; separating the mixture into at least two fractions, wherein an unbound fraction comprises unbound therapeutic proteins and a bound fraction comprises therapeutic protein-target complexes; c. for each of the unbound fraction and bound fraction, identifying and quantifying the abundance of a structure present on a species of the therapeutic protein, wherein the structure comprises an attribute of the therapeutic protein and, when the abundance of a structure in the unbound fraction is greater than the abundance of the structure in the bound fraction, the structure negatively affects the interaction between the therapeutic protein and the target,
A molecular sieve SCM-14, characterized in that the molecular sieve in its calcined form, has an X-ray diffraction pattern including the peaks as shown in Table A-1 or Table A-2 below, TABLE A-1 2θ (°) (a) d-distance (Å) (b) Relative intensity (I/I 0 × 100) 6.632 13.317 s-vs 8.384 10.537 s-vs 15.587 5.680 w-m 20.661 4.295 W 21.692 4.094 w-vs 25.693 3.464 w-m (a)=±0.3°, (b) is a function of 2 θ, TABLE A-2 2θ (°) (a) d-distance (Å) Relative intensity (I/I 0 × 100) 6.632 13.344 ±0.603 s-vs 8.384 10.551±0.377 s-vs 15.587 5.682±0.109 w-m 20.661 4.296±0.062 W 21.692 4.094±0.056 w-vs 25.693 3.465±0.040 w-m (a) = ±0.3 °, wherein the molecular sieve has a schematic chemical composition of formula "SiO 2 ·1/nGeO 2 ", wherein the molar ratio of silicon to germanium, n satisfies n ≦ 30.
An aroma composition comprising (a) hesperetin dihydrochalcone (I) (3-(3-Hydroxy-4-methoxy-phenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one) or a salt thereof, and (b) high fructose corn syrup (HFCS). (a) hesperetin dihydrochalcone (I) (3-(3-Hydroxy-4-methoxy-phenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one) or a salt thereof, and (b) high fructose corn syrup (HFCS).
A knit component , comprising: a knit-in tensile area , comprising: an opening at least partially bounded by a first intersecting portion (26a-d) and a second intersecting portion (26a-d); and a first course of tensile material that is integrally knitted with the first intersecting portion via a first knit stitch through interlooping, the first course of tensile material comprising a first float having a first float length and extending from the first intersecting portion, across the opening, to the second intersecting portion, thereby spanning the opening, wherein the first float length is at least three stitches long, wherein the first intersecting portion (26a-d) and the second intersecting portion (26a-d) include a first material of a first yarn, and wherein the tensile material comprises a higher stiffness and a larger diameter compared to the first material, the knit component being characterized in that each opening is bounded by a plurality of intersecting portions (26a-d) and a plurality of arterial portions (28a-d), the arterial portions (28a-d) connecting adjacent intersecting portions (26a-d), wherein each intersecting portion (26a-d) has a width (w) that exceeds its height (h), wherein the height of an intersecting portion (26a-d) increases with a number of courses within the respective intersecting portion (26a-d), and wherein the width of an intersecting portion (26a-d) increases with a number of wales within the respective intersecting portion (26a-d). an opening at least partially bounded by a first intersecting portion (26a-d) and a second intersecting portion (26a-d); and a first course of tensile material that is integrally knitted with the first intersecting portion via a first knit stitch through interlooping, the first course of tensile material comprising a first float having a first float length and extending from the first intersecting portion, across the opening, to the second intersecting portion, thereby spanning the opening, wherein the first float length is at least three stitches long, wherein the first intersecting portion (26a-d) and the second intersecting portion (26a-d) include a first material of a first yarn, and wherein the tensile material comprises a higher stiffness and a larger diameter compared to the first material, the knit component being characterized in that each opening is bounded by a plurality of intersecting portions (26a-d) and a plurality of arterial portions (28a-d), the arterial portions (28a-d) connecting adjacent intersecting portions (26a-d), wherein each intersecting portion (26a-d) has a width (w) that exceeds its height (h), wherein the height of an intersecting portion (26a-d) increases with a number of courses within the respective intersecting portion (26a-d), and wherein the width of an intersecting portion (26a-d) increases with a number of wales within the respective intersecting portion (26a-d).
Method of attaching a shrinkable label on a product wherein the shrinkable label comprises a multi-layered film comprising heat shrinkable material and photothermic material, the method comprising: - transporting the at least one product on a conveyor ; - arranging the at least one product in an irradiation volume , the irradiation volume being defined by a plurality of UV light emitters arranged to emit UV-light in the direction of at least a shrinkable label arranged around the at least one product; - controlling the UV-light emitters to irradiate the at least one shrinkable label arranged around the one or more products in the irradiation volume in order for the photothermic material to heat up causing the heat shrinkable material to shrink around the at least one product, wherein the UV light has a peak wavelength between 200 and 399 nm and at least 90% of the UV light is within a bandwidth of +/- 30 nm of the peak wavelength. - transporting the at least one product on a conveyor ; - arranging the at least one product in an irradiation volume , the irradiation volume being defined by a plurality of UV light emitters arranged to emit UV-light in the direction of at least a shrinkable label arranged around the at least one product; - controlling the UV-light emitters to irradiate the at least one shrinkable label arranged around the one or more products in the irradiation volume in order for the photothermic material to heat up causing the heat shrinkable material to shrink around the at least one product, wherein the UV light has a peak wavelength between 200 and 399 nm and at least 90% of the UV light is within a bandwidth of +/- 30 nm of the peak wavelength.
A portable wireless communications adapter comprising: a wireless receiver configured to receive wireless data over a Wireless Avionics Intra-Communication, WAIC, frequency range between 4.2 GHz and 4.4 GHz; a wireless transmitter configured to send wireless data over the WAIC frequency range between 4.2 GHz and 4.4 GHz; an electronic interface connector configured to mate with a portable electronic device for communication of the wireless data with the portable electronic device; and characterised by a location sensing module configured to: determine a location of the portable wireless communications adapter relative to an interior of an aircraft based on WAIC communications received at the wireless receiver; selectively enable the wireless transmitter to send wireless data in response to determining that the portable wireless communications adapter is located within the interior of the aircraft; and selectively disable the wireless transmitter to prevent the wireless transceiver from sending wireless data in response to determining that the portable wireless communications adapter is not located within the interior of the aircraft. a wireless receiver configured to receive wireless data over a Wireless Avionics Intra-Communication, WAIC, frequency range between 4.2 GHz and 4.4 GHz; a wireless transmitter configured to send wireless data over the WAIC frequency range between 4.2 GHz and 4.4 GHz; an electronic interface connector configured to mate with a portable electronic device for communication of the wireless data with the portable electronic device; and characterised by a location sensing module configured to: determine a location of the portable wireless communications adapter relative to an interior of an aircraft based on WAIC communications received at the wireless receiver; selectively enable the wireless transmitter to send wireless data in response to determining that the portable wireless communications adapter is located within the interior of the aircraft; and selectively disable the wireless transmitter to prevent the wireless transceiver from sending wireless data in response to determining that the portable wireless communications adapter is not located within the interior of the aircraft. determine a location of the portable wireless communications adapter relative to an interior of an aircraft based on WAIC communications received at the wireless receiver; selectively enable the wireless transmitter to send wireless data in response to determining that the portable wireless communications adapter is located within the interior of the aircraft; and selectively disable the wireless transmitter to prevent the wireless transceiver from sending wireless data in response to determining that the portable wireless communications adapter is not located within the interior of the aircraft.
A peristaltic pump comprising: a plunger movable to selectively engage a pumping volume of a tubing segment to expand the pumping volume to draw fluid flow into the pumping volume and to contract the pumping volume to conduct fluid flow from the pumping volume; a camshaft comprising a plunger cam lobe , wherein the plunger cam lobe is configured to move the plunger between an expansion position to draw fluid flow into the pumping volume and a contraction position to conduct fluid flow from the pumping volume; a first rocker coupled to the plunger; characterized by : a second rocker configured to contact the first rocker to urge the plunger toward the tubing segment, and the second rocker is actuated by the plunger cam lobe; a first biasing member coupled to the first rocker, the first biasing member configured to urge the plunger toward the tubing segment to maintain contact with the tubing segment during the expansion of the pumping volume, wherein the first biasing member has a first biasing force; and a second biasing member coupled to the second rocker, the second biasing member configured to urge the plunger toward the tubing segment to contract the pumping volume, wherein the second biasing member has a second biasing force and the first biasing force is less than the second biasing force. a second rocker configured to contact the first rocker to urge the plunger toward the tubing segment, and the second rocker is actuated by the plunger cam lobe; a first biasing member coupled to the first rocker, the first biasing member configured to urge the plunger toward the tubing segment to maintain contact with the tubing segment during the expansion of the pumping volume, wherein the first biasing member has a first biasing force; and a second biasing member coupled to the second rocker, the second biasing member configured to urge the plunger toward the tubing segment to contract the pumping volume, wherein the second biasing member has a second biasing force and the first biasing force is less than the second biasing force.
A surface emitting laser element formed of a group III nitride semiconductor comprising: a first clad layer of a first conductivity type; a first guide layer of the first conductivity type having a photonic crystal layer formed on the first clad layer including voids disposed having two-dimensional periodicity in a surface parallel to the first guide layer and a first embedding layer formed on the photonic crystal layer by mass transport without supplying a group III raw material wherein the first embedding layer closes the voids; a second embedding layer formed on the first embedding layer by crystal growth by supplying a group III raw material after the formation of the first embedding layer; an active layer formed on the second embedding layer; a second guide layer formed on the active layer; and a second clad layer of a second conductivity type formed on the second guide layer, the second conductivity type being a conductivity type opposite to the first conductivity type, wherein the first embedding layer has an upper surface including pits disposed at positions corresponding to the voids and which appear on the crystal orientation with respect to the voids, and an upper surface of the second embedding layer is an atomically flat plane having a step-terrace structure with a step height equivalent to a height of one bilayer of the constituent material of the second embedding layer. a first clad layer of a first conductivity type; a first guide layer of the first conductivity type having a photonic crystal layer formed on the first clad layer including voids disposed having two-dimensional periodicity in a surface parallel to the first guide layer and a first embedding layer formed on the photonic crystal layer by mass transport without supplying a group III raw material wherein the first embedding layer closes the voids; a second embedding layer formed on the first embedding layer by crystal growth by supplying a group III raw material after the formation of the first embedding layer; an active layer formed on the second embedding layer; a second guide layer formed on the active layer; and a second clad layer of a second conductivity type formed on the second guide layer, the second conductivity type being a conductivity type opposite to the first conductivity type, wherein the first embedding layer has an upper surface including pits disposed at positions corresponding to the voids and which appear on the crystal orientation with respect to the voids, and an upper surface of the second embedding layer is an atomically flat plane having a step-terrace structure with a step height equivalent to a height of one bilayer of the constituent material of the second embedding layer.
An electrical heating element for heating a fluid, comprising at least one tubular element through which a fluid flows or can flow, and with a ceramic heating resistor disposed in the tubular element , wherein the heating resistor comprises an arrangement of two open helicoid bodies having a respective central screw axis, the screw axes of the helicoid bodies being parallel to one another and the helicoid bodies being helically wound inside one another in a contactless manner, the central screw axes of the helicoid bodies being oriented substantially parallel to the central axis of the tubular element , the helicoid bodies being connected to one another in an electrically conducting manner in the region of one end of the helicoid arrangement and designed as separate connecting electrodes at an opposing further end of the helicoid arrangement, characterized in that the heating resistor being produced by sintering a green body, comprising at least one ceramic raw material, and comprising an electrically insulating component and an electrically conducting component, and the electrically insulating component forming a matrix in which the electrically conducting component is accommodated, wherein an electrically insulating element being disposed in at least one central cavity formed by the open helicoid bodies along the screw axes of the open helicoid bodies , the electrically insulating element having a tubular, rod-shaped or sectionally tubular and rod-shaped design, and the cross-sectional surface of the tubular element , in terms of shape and size, being only insignificantly larger than the maximum cross-sectional surface of the heating resistor .
Tapentadol for use in the treatment of pain associated with a disorder of the trigeminal nerve selected from the group consisting of trigeminal neuralgia and atypical facial pain, which is formulated for oral administration.
Method for preparing a reinforced structure comprising the following steps: a) forming the structure to be reinforced in the form of a receptacle, b) preparing a liquid thermosetting formulation at ambient temperature comprised between 18 °C and 25 °C, using a mixture of thermosetting polymer precursors, said liquid thermosetting formulation having a viscosity between 50 and 2,000 mPa.s, preferably between 50 and 600 mPa.s, c) pouring said liquid thermosetting formulation into said receptacle, d) adding a filler into said thermosetting formulation poured during step c), said filler having a granulometry comprised between 0.05 and 10mm, preferably between 0.1 and 3mm, a moisture content less than 0.1%, and advantageously having a density greater than the density of said thermosetting formulation, e) polymerising said thermosetting formulation with said filler, forming as such a reinforced structure, and f) possibly, pouring a finishing layer constituted of said liquid thermosetting formulation prepared during step b). a) forming the structure to be reinforced in the form of a receptacle, b) preparing a liquid thermosetting formulation at ambient temperature comprised between 18 °C and 25 °C, using a mixture of thermosetting polymer precursors, said liquid thermosetting formulation having a viscosity between 50 and 2,000 mPa.s, preferably between 50 and 600 mPa.s, c) pouring said liquid thermosetting formulation into said receptacle, d) adding a filler into said thermosetting formulation poured during step c), said filler having a granulometry comprised between 0.05 and 10mm, preferably between 0.1 and 3mm, a moisture content less than 0.1%, and advantageously having a density greater than the density of said thermosetting formulation, e) polymerising said thermosetting formulation with said filler, forming as such a reinforced structure, and f) possibly, pouring a finishing layer constituted of said liquid thermosetting formulation prepared during step b).
A method for interconnecting equipment within an aircraft, the method comprising: installing a multi-dimensional backplane within the aircraft across a plurality of frame bays associated with the aircraft , the backplane including a plurality of connectors mounted thereon, the connectors interconnected by one or more of the following formed within the backplane : an electrical conductor, an optical waveguide, a pneumatic line, and a hydraulic line; attaching shipside wiring to a first portion of the connectors on the backplane ; and attaching connectors of the equipment to corresponding connectors on the backplane . installing a multi-dimensional backplane within the aircraft across a plurality of frame bays associated with the aircraft , the backplane including a plurality of connectors mounted thereon, the connectors interconnected by one or more of the following formed within the backplane : an electrical conductor, an optical waveguide, a pneumatic line, and a hydraulic line; attaching shipside wiring to a first portion of the connectors on the backplane ; and attaching connectors of the equipment to corresponding connectors on the backplane .
A device interchangeably usable by a robot and a human , wherein the device comprises: a base unit including a robot connector for connection to the robot , at least one of a surface grippable by the human and a grip grippable by the human, a communications unit for wireless communication with a control station , a processor connected to the communications unit , an energy storage for powering at least the communications unit and the processor , and means adapted to detect whether the device is connected to the robot or used directly by the human ; and a tool for performing an operation related to a vehicle or a vehicle related object, which tool is connected to the base unit , wherein the processor is configured to control the tool , and wherein the device is adapted to be controlled by the control station to perform at least some of the operation related to a vehicle or a vehicle related object if said means detects that the device is connected to the robot . a base unit including a robot connector for connection to the robot , at least one of a surface grippable by the human and a grip grippable by the human, a communications unit for wireless communication with a control station , a processor connected to the communications unit , an energy storage for powering at least the communications unit and the processor , and means adapted to detect whether the device is connected to the robot or used directly by the human ; and a tool for performing an operation related to a vehicle or a vehicle related object, which tool is connected to the base unit , wherein the processor is configured to control the tool , and wherein the device is adapted to be controlled by the control station to perform at least some of the operation related to a vehicle or a vehicle related object if said means detects that the device is connected to the robot .