mhurhangee/patent-ind-claim-en huggingface dataset:
A solid pharmaceutical composition comprising: (a) an active di chain BoNT/E1 protein, wherein the first chain comprises a sequence of contiguous amino acids, and wherein said sequence of contiguous amino acids has at least 95% sequence identity to the amino acid sequence of positions 1-419 of SEQ ID NO: 2; wherein the second chain comprises a sequence of contiguous amino acids, and wherein said sequence of contiguous amino acids has at least 95% sequence identity to the amino acid sequence of positions 423-1252 of SEQ ID NO: 2; wherein the first and second chains are joined together by a disulphide bond between cysteine 412 on the first chain and cysteine 426 on the second chain; with the proviso that said sequence of contiguous amino acids includes one or more of the following amino acids (wherein the amino acid position numbering starts with the N-terminal amino acid residue and ends with the C-terminal amino acid residue of the BoNT/E1 protein): glycine at position 177 serine at position 198 alanine at position 340 leucine at position 773 leucine at position 963 glutamine at position 964 alanine at position 967 asparagine at position 1195, and wherein said sequence of contiguous amino acids does not include residues 420, 421 and 422 of SEQ ID NO: 2; and (b) a stabilising agent. (a) an active di chain BoNT/E1 protein, wherein the first chain comprises a sequence of contiguous amino acids, and wherein said sequence of contiguous amino acids has at least 95% sequence identity to the amino acid sequence of positions 1-419 of SEQ ID NO: 2; wherein the second chain comprises a sequence of contiguous amino acids, and wherein said sequence of contiguous amino acids has at least 95% sequence identity to the amino acid sequence of positions 423-1252 of SEQ ID NO: 2; wherein the first and second chains are joined together by a disulphide bond between cysteine 412 on the first chain and cysteine 426 on the second chain; with the proviso that said sequence of contiguous amino acids includes one or more of the following amino acids (wherein the amino acid position numbering starts with the N-terminal amino acid residue and ends with the C-terminal amino acid residue of the BoNT/E1 protein): glycine at position 177 serine at position 198 alanine at position 340 leucine at position 773 leucine at position 963 glutamine at position 964 alanine at position 967 asparagine at position 1195, and wherein said sequence of contiguous amino acids does not include residues 420, 421 and 422 of SEQ ID NO: 2; and glycine at position 177 serine at position 198 alanine at position 340 leucine at position 773 leucine at position 963 glutamine at position 964 alanine at position 967 asparagine at position 1195, and wherein said sequence of contiguous amino acids does not include residues 420, 421 and 422 of SEQ ID NO: 2; and (b) a stabilising agent.
A method of wireless communications, comprising: receiving , from a network entity, an indication including: a duration of at least one of one or more first transmission opportunities or one or more second transmission opportunities within at least one frame, and a priority for each of a first operator and a second operator on each of the one or more first or second transmission opportunities; and transmitting the at least one frame, wherein the frame includes a first acquisition interval associated with the first operator and the one or more first transmission opportunities having a guarantee interval for the first operator, and a second acquisition interval associated with the second operator different from the first operator and the one or more second transmission opportunities having a guarantee interval for the second operator, the first acquisition interval and the one or more first transmission opportunities non-overlapping with the second acquisition interval and the one or more second transmission opportunities, wherein the first acquisition interval is adjacent to the second acquisition interval and followed by the one or more first transmission opportunities and the one or more second transmission opportunities. a duration of at least one of one or more first transmission opportunities or one or more second transmission opportunities within at least one frame, and a priority for each of a first operator and a second operator on each of the one or more first or second transmission opportunities; and transmitting the at least one frame, wherein the frame includes a first acquisition interval associated with the first operator and the one or more first transmission opportunities having a guarantee interval for the first operator, and a second acquisition interval associated with the second operator different from the first operator and the one or more second transmission opportunities having a guarantee interval for the second operator, the first acquisition interval and the one or more first transmission opportunities non-overlapping with the second acquisition interval and the one or more second transmission opportunities, wherein the first acquisition interval is adjacent to the second acquisition interval and followed by the one or more first transmission opportunities and the one or more second transmission opportunities.
A design method for a diffractive optical element for projecting an oblique line (L) onto a surface, characterized in that the design method comprises: determining an angle θ between the oblique line (L) and a first direction (S101); determining, according to the angle, a first period d1 of the diffractive optical element in the first direction and a second period d2 of the diffractive optical element in a second direction, wherein the first direction is perpendicular to the second direction (S102); the first period d1 indicates a length of each microstructure pattern unit of the diffractive optical element in the first direction, and the second period d2 indicates a length of each microstructure pattern unit of the diffractive optical element in the second direction; the first period d1 and the second period d2 satisfy tg θ = d1/d2; and calculating, with a computer program, a phase distribution map of the diffractive optical element according to the first period d1, the second period d2 and a target pattern with an oblique line at 45° based on an iterative Fourier transform algorithm (S103). determining an angle θ between the oblique line (L) and a first direction (S101); determining, according to the angle, a first period d1 of the diffractive optical element in the first direction and a second period d2 of the diffractive optical element in a second direction, wherein the first direction is perpendicular to the second direction (S102); the first period d1 indicates a length of each microstructure pattern unit of the diffractive optical element in the first direction, and the second period d2 indicates a length of each microstructure pattern unit of the diffractive optical element in the second direction; the first period d1 and the second period d2 satisfy tg θ = d1/d2; and calculating, with a computer program, a phase distribution map of the diffractive optical element according to the first period d1, the second period d2 and a target pattern with an oblique line at 45° based on an iterative Fourier transform algorithm (S103).
Hollow profile for the construction of an opening frame , in particular a sliding opening frame, of a glazed opening, said opening frame being intended to cooperate with a fixed frame of the glazed opening, said hollow profile including: - two respectively called central and connection cells, each of said cells including a first wall intended to extend in a mean plane normal to the glazed opening, a second wall opposite said first wall , as well as side walls connecting said first and second walls, - side cells arranged on either side of said central and connecting cells, - fixing means intended to hold a glazing bead profile of the opening frame in a stable position and in a reversible manner, - assembly means intended to hold protective profiles of the opening frame in a stable position and in a reversible manner, said hollow profile being characterised in that it is made of polyamide material filled with fibreglass. - two respectively called central and connection cells, each of said cells including a first wall intended to extend in a mean plane normal to the glazed opening, a second wall opposite said first wall , as well as side walls connecting said first and second walls, - side cells arranged on either side of said central and connecting cells, - fixing means intended to hold a glazing bead profile of the opening frame in a stable position and in a reversible manner, - assembly means intended to hold protective profiles of the opening frame in a stable position and in a reversible manner,
A method comprising, responsive to download electronic file transfer requests generated by a plurality of mobile device applications operated by a mobile wireless communications device , a controller of the mobile wireless communications device downloading, via at least one wireless transceiver , requested electronic files using a common file transfer application.
A humidifier of a type which is used for heating and humidifying a flow of respiratory gases supplied to a user, said humidifier adapted to heat the contents of a humidifier chamber which is removably attached in use to said humidifier, said humidifier comprising: a casing or base unit, adapted to hold said humidifier chamber in position relative to said humidifier, a heater base assembly fixed to said casing or base unit, the heater base assembly comprising: a heater plate having a thermally conductive portion and a perimeter portion around the perimeter of said heater plate , characterised by a resilient member having a first portion coupled to said heater plate and a second portion adapted to provide a flange around at least part of said perimeter portion , said resilient member adapted to allow said heater base assembly to be fixed to the humidifier in use by said flange in such a manner that said heater plate and said first portion can move relative to the humidifier in use, and said heater base assembly fixed to said casing or base unit by said flange in such a manner that said heater plate and said first portion can move relative to said casing or base unit; and wherein at least a portion of the second portion of the resilient member is clamped in a sandwiched arrangement between two humidifier components. a casing or base unit, adapted to hold said humidifier chamber in position relative to said humidifier, a heater base assembly fixed to said casing or base unit, the heater base assembly comprising: a heater plate having a thermally conductive portion and a perimeter portion around the perimeter of said heater plate , characterised by a resilient member having a first portion coupled to said heater plate and a second portion adapted to provide a flange around at least part of said perimeter portion , said resilient member adapted to allow said heater base assembly to be fixed to the humidifier in use by said flange in such a manner that said heater plate and said first portion can move relative to the humidifier in use, and a heater plate having a thermally conductive portion and a perimeter portion around the perimeter of said heater plate , characterised by a resilient member having a first portion coupled to said heater plate and a second portion adapted to provide a flange around at least part of said perimeter portion , said resilient member adapted to allow said heater base assembly to be fixed to the humidifier in use by said flange in such a manner that said heater plate and said first portion can move relative to the humidifier in use, and said heater base assembly fixed to said casing or base unit by said flange in such a manner that said heater plate and said first portion can move relative to said casing or base unit; and wherein at least a portion of the second portion of the resilient member is clamped in a sandwiched arrangement between two humidifier components.
A pump assembly comprising a motor , a gearbox , a rotational to reciprocal action transmission and a diaphragm pump , in which a shaft of said motor, an output shaft of said gearbox, a reciprocal movement axis of said transmission and a pump shaft of said diaphragm pump are all aligned on a main axis (A-A), in which said output shaft of said gearbox is in the form of a rotor , in which said transmission comprises a sleeve connected to said rotor, said sleeve being rotationally static in relation to the rotor and freely axially moveable relative to the rotor , and an annular track arranged around said sleeve , in which said sleeve comprises a plurality of radially extending arms , in which said track comprises an annular path with axially extending formations , in which outer ends of said arms are disposed on said track , and in which said sleeve is axially statically connected to said pump shaft .
A method for printing variable copies of a plurality of pages in a document, the method comprising: receiving, by a printer driver unit , a user input comprising a number of copies for each of the plurality of pages to be printed wherein the user input is received through a driver user interface of the printer driver unit ; parsing, by the printer driver unit, the user input to determine the plurality of pages to be printed and transmitting the information related to the pages selected and the number of copies to a graphics device interface which is operatively interfaced with the printer driver unit, wherein said graphics device interface is configured to pass content to be printed to a printing unit via a print spooler receiving by the graphics device interface content of all the pages of the document through a printer application, retrieving, by the printer driver unit, content of each of the plurality of pages determined among the content of all the pages of the document; and printing, by the printer driver unit, the determined number of copies of the retrieved content, wherein the printing further comprises: sending to the printing unit a Printer Job Language (PJL) command indicating the plurality of pages to be printed and the number of copies for each of the plurality of pages to be printed. receiving, by a printer driver unit , a user input comprising a number of copies for each of the plurality of pages to be printed wherein the user input is received through a driver user interface of the printer driver unit ; parsing, by the printer driver unit, the user input to determine the plurality of pages to be printed and transmitting the information related to the pages selected and the number of copies to a graphics device interface which is operatively interfaced with the printer driver unit, wherein said graphics device interface is configured to pass content to be printed to a printing unit via a print spooler receiving by the graphics device interface content of all the pages of the document through a printer application, retrieving, by the printer driver unit, content of each of the plurality of pages determined among the content of all the pages of the document; and printing, by the printer driver unit, the determined number of copies of the retrieved content, wherein the printing further comprises: sending to the printing unit a Printer Job Language (PJL) command indicating the plurality of pages to be printed and the number of copies for each of the plurality of pages to be printed.
A transmission for a vehicle, the transmission comprising a housing and a valve block arranged in the housing, and a parking lock mechanism , the parking lock mechanism having a wheel rotationally locked to a shaft of the transmission, a pawl and a hydraulic actuator arranged for engagement of the wheel and the pawl for locking the shaft , the actuator being hydraulically connected to the valve block such that the actuator is supplied by hydraulic fluid from the valve block, the actuator being a hydraulic cylinder with a cylinder portion, a piston and a piston rod , the hydraulic cylinder being arranged for moving the pawl between an engaged position and a disengaged position by means of the piston rod , characterized in that in addition to an engaged position and a disengaged position , the piston rod has an assembly position facilitating assembling of the valve block together with the hydraulic cylinder in the transmission , and the piston rod has locking positions for the engagement position, disengagement position and assembly position, the locking position for the assembly position constituting the locking position where the piston rod is most retracted
A steam generator comprising a system for regulating condensation of a flue gas in the steam generator , wherein the steam generator comprises a component being in heating-contact with the flue gas , the system comprising: a temperature controller configured to control a temperature of said component being in heating-contact with the flue gas ; a flue gas analyzer configured to communicate with the temperature controller and to obtain a measurement of an amount of an acid-forming compound in the flue gas ; and wherein the temperature controller adjusts the temperature of the component based at least in part on the measurement such that the temperature of the component is above an acid dew point of the flue gas when the component is in heating-contact with the flue gas , characterized in that the component forms a conduit that contains a working-medium , and is arranged and configured so that the flue gas flows around the conduit, and the temperature controller is adapted and configured to control the temperature of the component via controlling a temperature of the working-medium . a temperature controller configured to control a temperature of said component being in heating-contact with the flue gas ; a flue gas analyzer configured to communicate with the temperature controller and to obtain a measurement of an amount of an acid-forming compound in the flue gas ; and wherein the temperature controller adjusts the temperature of the component based at least in part on the measurement such that the temperature of the component is above an acid dew point of the flue gas when the component is in heating-contact with the flue gas , characterized in that the component forms a conduit that contains a working-medium , and is arranged and configured so that the flue gas flows around the conduit, and the temperature controller is adapted and configured to control the temperature of the component via controlling a temperature of the working-medium .
An anti-AXL antibody comprising a light chain variable domain of sequence SEQ ID NO. 7 and a heavy chain variable domain of sequence SEQ ID NO. 8.
A method of determining the location of a device comprising a radio transceiver, the method comprising: - receiving in a mobile locator device a radio signal from said device , - determining a distance to said device from the locator device at the position of the locator device said determined distance having a determined distance accuracy and/or determine a direction to the device with a determined direction accuracy, wherein said determined distance and or direction is based on the radio signal received from the device , - forming a geographical area limited by two concentric circles with boundaries set as the determined distance +/- said determined accuracy, and/or limited by the determined direction +/- said determined direction accuracy, characterized by - subdividing said geographical area into a number of sub-areas, - moving said locator device and removing any sub-area that is not included in all geographical areas formed for each new position or direction of the locator device , - repeating moving of said locator device and repeating removal of sub-areas for new positions of the locator device until the total area of the remaining sub-areas is below a threshold value, and - determining the location of the device as the area of the remaining sub-areas. - receiving in a mobile locator device a radio signal from said device , - determining a distance to said device from the locator device at the position of the locator device said determined distance having a determined distance accuracy and/or determine a direction to the device with a determined direction accuracy, wherein said determined distance and or direction is based on the radio signal received from the device , - forming a geographical area limited by two concentric circles with boundaries set as the determined distance +/- said determined accuracy, and/or limited by the determined direction +/- said determined direction accuracy, characterized by - subdividing said geographical area into a number of sub-areas, - moving said locator device and removing any sub-area that is not included in all geographical areas formed for each new position or direction of the locator device , - repeating moving of said locator device and repeating removal of sub-areas for new positions of the locator device until the total area of the remaining sub-areas is below a threshold value, and - determining the location of the device as the area of the remaining sub-areas.
A device in the form of an exoskeleton or a proxy, whereby the device comprises a first member , a second member , a third member , and a fourth member , wherein - the first member is connected to a first rotary joint via which the second member is rotatably supported about a first axis , - the second member is connected to a second rotary joint via which the third member is rotatably supported about a second axis , - the third member is connected to a third rotary joint via which the fourth member is rotatably supported about a third axis for the purpose of the flexion/extension of a thigh, - the axes pass through a common point , and - the first axis with the second axis forms a first angle (φ 1 ) and the second axis with the third axis forms a second angle (φ 2 ), - the first axis may be rotated about a vertical axis passing through the common point by a third angle (α), - the first axis may be rotated about a horizontal axis passing through the common point by a fourth angle (β) with a value unequal to zero. - the first member is connected to a first rotary joint via which the second member is rotatably supported about a first axis , - the second member is connected to a second rotary joint via which the third member is rotatably supported about a second axis , - the third member is connected to a third rotary joint via which the fourth member is rotatably supported about a third axis for the purpose of the flexion/extension of a thigh, - the axes pass through a common point , and - the first axis with the second axis forms a first angle (φ 1 ) and the second axis with the third axis forms a second angle (φ 2 ), - the first axis may be rotated about a vertical axis passing through the common point by a third angle (α), - the first axis may be rotated about a horizontal axis passing through the common point by a fourth angle (β) with a value unequal to zero.
A roof box for a public transport vehicle , the box being adapted to be secured to the roof of the vehicle , the box comprising a framework and a shell secured to the framework , characterised in that the framework being configured to support the casing , the casing delimiting an internal volume of the boot , the casing comprising a set of metal sheets separating the internal volume from the exterior of the box , the box being characterised in that each metal sheet is assembled to the framework and welded to at least one other sheet .
A solid solution ceramic material having a general chemical formula (I): (I): x(Bi 0.5 Na 0.5 )TiO 3 -y(Bi 0.5 K 0.5 )TiO 3 -z 1 SrHfO 3 -z 2 SrZrO 3 wherein: x + y + z 1 + z 2 = 1 ; y , z 1 + z 2 ≠ 0 ; x ≥ 0 ; and wherein the ceramic material comprises at least 70 vol.% of a pseudo-cubic phase having an axial ratio c/a of from 0.995 to 1.005 and/or a rhombohedral angle of 90 ± 0.5 degrees and wherein the ceramic material is capable of undergoing a field induced reversible transition from the pseudo-cubic phase to a tetragonal phase having an axial ratio c/a of between 1.005 and 1.02.