mhurhangee/patent-ind-claim-en huggingface dataset:
A multispecific antigens-binding fragment comprising at least the two following different Fab fragments: : - a wild-type Fab fragment consisting of wild-type CH1 and CL domains of an immunoglobulin, and the VH and VL domains of an antibody recognizing an epitope of interest; and - a mutated Fab fragment consisting of: • the VH and VL domains of an antibody recognizing an epitope of interest; • a CH1 domain of the IgG isotype which is derived from the CH1 domain of a human immunoglobulin by substitution of the threonine residue at position 192 of said CH1 domain with a glutamic acid residue, wherein sequence position numbers refer to Kabat numbering; and • a CL domain of the kappa type which is derived from the CL domain of a human immunoglobulin by substitution of the asparagine residue at position 137 of said CL domain with a lysine residue and substitution of the serine residue at position 114 of said CL domain with an alanine residue, wherein sequence position numbers refer to Kabat numbering; wherein each Fab fragment recognizes a different epitope of interest, and said Fab fragments being tandemly arranged in any order, the C-terminal end of the CH1 domain of a first Fab fragment being linked to the N-terminal end of the VH domain of the following Fab fragment through a polypeptide linker. - a wild-type Fab fragment consisting of wild-type CH1 and CL domains of an immunoglobulin, and the VH and VL domains of an antibody recognizing an epitope of interest; and - a mutated Fab fragment consisting of: • the VH and VL domains of an antibody recognizing an epitope of interest; • a CH1 domain of the IgG isotype which is derived from the CH1 domain of a human immunoglobulin by substitution of the threonine residue at position 192 of said CH1 domain with a glutamic acid residue, wherein sequence position numbers refer to Kabat numbering; and • a CL domain of the kappa type which is derived from the CL domain of a human immunoglobulin by substitution of the asparagine residue at position 137 of said CL domain with a lysine residue and substitution of the serine residue at position 114 of said CL domain with an alanine residue, wherein sequence position numbers refer to Kabat numbering; • the VH and VL domains of an antibody recognizing an epitope of interest; • a CH1 domain of the IgG isotype which is derived from the CH1 domain of a human immunoglobulin by substitution of the threonine residue at position 192 of said CH1 domain with a glutamic acid residue, wherein sequence position numbers refer to Kabat numbering; and • a CL domain of the kappa type which is derived from the CL domain of a human immunoglobulin by substitution of the asparagine residue at position 137 of said CL domain with a lysine residue and substitution of the serine residue at position 114 of said CL domain with an alanine residue, wherein sequence position numbers refer to Kabat numbering;
Nebulizer for a fluid comprising: a replaceable container containing the fluid , a lock locking the nebulizer against further use in a first locked state when the container has to be replaced, wherein the first locked state is reset by resetting the lock if the container has been replaced, and a control member for controlling or driving the lock , wherein the control member is driven by the force of a spring , characterized in that the nebulizer is adapted to show one or more different or consecutive numbers alternately with one or more symbols indicating container replacement, and that the control member is ring-like and rotated stepwise by the force of the spring . a replaceable container containing the fluid , a lock locking the nebulizer against further use in a first locked state when the container has to be replaced, wherein the first locked state is reset by resetting the lock if the container has been replaced, and a control member for controlling or driving the lock , wherein the control member is driven by the force of a spring , characterized in that the nebulizer is adapted to show one or more different or consecutive numbers alternately with one or more symbols indicating container replacement, and that the control member is ring-like and rotated stepwise by the force of the spring .
Braking resistor for a vehicle which is equipped with an electrodynamic braking device, the braking resistor having a plurality of elongate, cylindrical heating cartridges which are parallel to one another and are supported on at least two support carrier portions of a support carrier , the heating cartridges being held by means of a bearing arrangement which comprises locating bearings which preload the heating cartridges in the direction of the support carrier portions , characterized in that the locating bearings each have a locating bearing carrier portion , running along one of the heating cartridges , of a locating bearing support and a locating bearing retaining bracket which is fastened elastically against the locating bearing carrier portion .
A system comprising: a lavatory including a toilet ; and a foot washing system , the foot washing system comprising: a support panel ; and a basin including a foot-washing area and a drain that is configured to drain water out of the foot-washing area, wherein the basin is moveably coupled to the support panel, wherein the basin is selectively moveable between a stowed position and a deployed position in relation to the support panel, wherein the deployed position allows for foot washing within the foot-washing area, wherein the basin is positioned away from the toilet in the stowed position, characterised in that the drain of the basin in the deployed position is positioned directly over a bowl of the toilet , and in that the basin in the deployed position is directly supported by the bowl of the toilet. a lavatory including a toilet ; and a foot washing system , the foot washing system comprising: a support panel ; and a basin including a foot-washing area and a drain that is configured to drain water out of the foot-washing area, wherein the basin is moveably coupled to the support panel, wherein the basin is selectively moveable between a stowed position and a deployed position in relation to the support panel, wherein the deployed position allows for foot washing within the foot-washing area, wherein the basin is positioned away from the toilet in the stowed position, characterised in that the drain of the basin in the deployed position is positioned directly over a bowl of the toilet , and in that the basin in the deployed position is directly supported by the bowl of the toilet. a support panel ; and a basin including a foot-washing area and a drain that is configured to drain water out of the foot-washing area, wherein the basin is moveably coupled to the support panel, wherein the basin is selectively moveable between a stowed position and a deployed position in relation to the support panel, wherein the deployed position allows for foot washing within the foot-washing area, wherein the basin is positioned away from the toilet in the stowed position, characterised in that the drain of the basin in the deployed position is positioned directly over a bowl of the toilet , and in that the basin in the deployed position is directly supported by the bowl of the toilet.
A cladding assembly for a fenestration product, the assembly comprising: a core element ; a cladding element ; a first attachment formation comprising a projection ; a second attachment formation comprising at least one engagement surface that at least partly surrounds an open ended recess , wherein the core element carries one of the first and second attachment formations and the cladding element carries the other of the first and second attachment formations such that the cladding element can be releasably or permanently attached to the core element by the first and second attachment formations; a third attachment formation comprising a first retaining member , the first retaining member comprising an elongate body with a latch arrangement substantially at or adjacent one end, wherein the third attachment formation comprises a second retaining member which is spaced apart from the first retaining member , the second retaining member comprising an elongate body with a latch arrangement substantially at or adjacent one end; and a fourth attachment formation comprising a third retaining member , the third retaining member comprising an elongate body with a latch arrangement substantially at or adjacent one end and being positioned on one side of the elongate body , the third retaining member comprising a further latch arrangement being positioned on the opposite side of the elongate body to the latch arrangement , characterised in that the recess has an enlarged portion and a narrowed portion, wherein the projection is configured to be at least partly received in the recess to releasably or permanently attach the first attachment formation to the second attachment formation. a core element ; a cladding element ; a first attachment formation comprising a projection ; a second attachment formation comprising at least one engagement surface that at least partly surrounds an open ended recess , wherein the core element carries one of the first and second attachment formations and the cladding element carries the other of the first and second attachment formations such that the cladding element can be releasably or permanently attached to the core element by the first and second attachment formations; a third attachment formation comprising a first retaining member , the first retaining member comprising an elongate body with a latch arrangement substantially at or adjacent one end, wherein the third attachment formation comprises a second retaining member which is spaced apart from the first retaining member , the second retaining member comprising an elongate body with a latch arrangement substantially at or adjacent one end; and
A method for establishing a communication connection between a network node and a communication partner in a data network , wherein the network node receives at least one message (M) via a wireless interface from the communication partner and wherein verification data is attached to the verification message (M), characterized in that the verification data comprise a transmitter measured data image , which is representative of measured data acquired by the communication partner in a preceding recording period in a certain time range, wherein the network node verifies the communication partner by a comparison, based on a correlation known to the network node and/or communicated by the communication partner to the network node , of the transmitter measured data image contained in the received verification data with a receiver measured data image , which has been created separately from the transmitter measured data image , and which is stored in a data memory of the network node and wherein matching measured data images prove that the communication partner is in the same measurement environment as the network node .
Tool for overmolding and/or back-molding a curved glass body, the tool having a first surface for placing the curved glass body, the tool comprising a plurality of pins , the pins each having a first end face at a first end of the pins , at least a portion of the first surface being formed by the first end faces of the pins , the pins being mounted displaceably along their longitudinal direction , so that at least the portion of the first surface is adaptable to a contour of the curved glass body, characterized in that the pins are arranged so as to be lined up in rows and columns , so that the first end faces thereof form a flush curved surface in a corresponding position in the longitudinal direction . the tool having a first surface for placing the curved glass body, the tool comprising a plurality of pins , the pins each having a first end face at a first end of the pins , at least a portion of the first surface being formed by the first end faces of the pins , the pins being mounted displaceably along their longitudinal direction , so that at least the portion of the first surface is adaptable to a contour of the curved glass body, characterized in that the pins are arranged so as to be lined up in rows and columns , so that the first end faces thereof form a flush curved surface in a corresponding position in the longitudinal direction .
A torque sensor system for a pedelec, comprising a middle shaft , an annular gear , a planetary gear train , a sun gear output shaft , and a signal processing component which are engaged in turn; wherein: the signal processing component is provided for measuring a performance of an applied force, converting measuring results thereof to an electric signal, and outputting the electric signal; characterized in that the planetary gear train acts as a power input unit, and the annular gear acts as a power output unit; a pressure conversion device is provided for receiving a first applied force generated by the power output unit and then converting the first applied force to a second applied force based on a lever principle; the pressure conversion device is engaged in turn with the annular gear , the planetary gear train , the sun gear output shaft , and the signal processing component ; and the signal processing component is provided for measuring a performance of the second applied force, wherein the middle shaft serves as an input shaft, which is fixed with a planetary support of the planetary gear train through a spline structure, and the planetary gear train is driven by the middle shaft ; a relative movement exists between the planetary gear train and the sun gear output shaft ; a torque signal acting on the middle shaft is converted to a pressure signal by the annular gear combined with the pressure conversion device , and the pressure signal is converted to an electric signal and then transmitted to a controller by the signal processing component ; and finally, a torque feedback is achieved. the signal processing component is provided for measuring a performance of an applied force, converting measuring results thereof to an electric signal, and outputting the electric signal; characterized in that the planetary gear train acts as a power input unit, and the annular gear acts as a power output unit; a pressure conversion device is provided for receiving a first applied force generated by the power output unit and then converting the first applied force to a second applied force based on a lever principle; the pressure conversion device is engaged in turn with the annular gear , the planetary gear train , the sun gear output shaft , and the signal processing component ; and the signal processing component is provided for measuring a performance of the second applied force, wherein the middle shaft serves as an input shaft, which is fixed with a planetary support of the planetary gear train through a spline structure, and the planetary gear train is driven by the middle shaft ; a relative movement exists between the planetary gear train and the sun gear output shaft ; a torque signal acting on the middle shaft is converted to a pressure signal by the annular gear combined with the pressure conversion device , and the pressure signal is converted to an electric signal and then transmitted to a controller by the signal processing component ; and finally, a torque feedback is achieved.
A seed meter assembly comprising: a motor ; a seed reservoir configured to support seeds; and a metering member having a seed side facing the seed reservoir and a non-seed side opposite the seed side, wherein the motor is configured to drive the metering member in a rotational direction moving from upstream towards downstream, the metering member including: a plurality of apertures extending from the seed side to the non-seed side for picking up seeds from the seed reservoir under the influence of a pressure differential, and a cell diverging from an aperture of the plurality of apertures towards the seed side to define a surface recessed therefrom, the cell configured to receive one of the seeds, the cell being elongated between a first end defining a furthest extent of the cell in an upstream direction and a second end defining a furthest extent of the cell in a downstream direction, characterized in that the aperture of the plurality of apertures is disposed closer to the second end than to the first end . a motor ; a seed reservoir configured to support seeds; and a metering member having a seed side facing the seed reservoir and a non-seed side opposite the seed side, wherein the motor is configured to drive the metering member in a rotational direction moving from upstream towards downstream, the metering member including: a plurality of apertures extending from the seed side to the non-seed side for picking up seeds from the seed reservoir under the influence of a pressure differential, and a cell diverging from an aperture of the plurality of apertures towards the seed side to define a surface recessed therefrom, the cell configured to receive one of the seeds, the cell being elongated between a first end defining a furthest extent of the cell in an upstream direction and a second end defining a furthest extent of the cell in a downstream direction, characterized in that the aperture of the plurality of apertures is disposed closer to the second end than to the first end . a plurality of apertures extending from the seed side to the non-seed side for picking up seeds from the seed reservoir under the influence of a pressure differential, and a cell diverging from an aperture of the plurality of apertures towards the seed side to define a surface recessed therefrom, the cell configured to receive one of the seeds, the cell being elongated between a first end defining a furthest extent of the cell in an upstream direction and a second end defining a furthest extent of the cell in a downstream direction, characterized in that the aperture of the plurality of apertures is disposed closer to the second end than to the first end .
Freestanding guide rail for an elevator system , comprising an elongate profile body which can be detachably fastened to a wall of an elevator shaft of the elevator system , the profile body predominantly consisting of concrete, characterized in that at least one guide surface of the guide rail that is formed by an outer surface of the guide rail is at least predominantly made of concrete.
A biomedical container to collect and test blood or a blood component, comprising: - a collection chamber for blood or a blood component; - a test chamber for blood or a blood component; and - a test kit in the test chamber to test the blood or the blood component contained therein; wherein the collection chamber and the test chamber are intended to be connected so as to be unequivocally mutually associated and to be supplied with the same blood or blood component. - a collection chamber for blood or a blood component; - a test chamber for blood or a blood component; and - a test kit in the test chamber to test the blood or the blood component contained therein; wherein the collection chamber and the test chamber are intended to be connected so as to be unequivocally mutually associated and to be supplied with the same blood or blood component.
A non-aqueous electrolyte, comprising a non-aqueous solvent, a lithium salt, and an additive, wherein the non-aqueous solvent comprises a carbonate solvent and a high oxidation potential solvent, and the additive comprises cyclic sulfate; the high oxidation potential solvent is selected from one or more of compounds represented by formula I and formula II; in formula I, R 1 and R 2 are independently selected from unsubstituted, partially halogenated, or fully halogenated alkyl groups having 1 to 5 carbon atoms, and at least one of Ri and R 2 is a partially halogenated or fully halogenated alkyl group having 1 to 5 carbon atoms; and in formula II, R 3 is selected from partially halogenated or fully halogenated alkylene groups having 2 to 6 carbon atoms; the cyclic sulfate is selected from one or more of compounds represented by formula III; in formula III, R4 is selected from unsubstituted, partially halogenated, or fully halogenated alkylene groups having 1 to 6 carbon atoms; and a halogen atom is selected from one or more of F, Cl, Br, and I, and preferably, the halogen atom is F; wherein based on a total weight of the non-aqueous solvent, a weight percentage of the high oxidation potential solvent is 10% to 60%; and a weight percentage of the carbonate solvent is 40% to 90%. the non-aqueous solvent comprises a carbonate solvent and a high oxidation potential solvent, and the additive comprises cyclic sulfate; the high oxidation potential solvent is selected from one or more of compounds represented by formula I and formula II; in formula I, R 1 and R 2 are independently selected from unsubstituted, partially halogenated, or fully halogenated alkyl groups having 1 to 5 carbon atoms, and at least one of Ri and R 2 is a partially halogenated or fully halogenated alkyl group having 1 to 5 carbon atoms; and in formula II, R 3 is selected from partially halogenated or fully halogenated alkylene groups having 2 to 6 carbon atoms; the cyclic sulfate is selected from one or more of compounds represented by formula III; in formula III, R4 is selected from unsubstituted, partially halogenated, or fully halogenated alkylene groups having 1 to 6 carbon atoms; and a halogen atom is selected from one or more of F, Cl, Br, and I, and preferably, the halogen atom is F; wherein based on a total weight of the non-aqueous solvent, a weight percentage of the high oxidation potential solvent is 10% to 60%; and a weight percentage of the carbonate solvent is 40% to 90%.
A method of contactless communication of an object with a reader by active load modulation, comprising a first communication mode comprising generating a main clock signal (SH1) within said object including a calibration phase comprising locking the output signal (SSP) of a controlled main oscillator (OSCP) onto the phase and frequency of a secondary clock signal (SH2) received from the reader (RD) and estimating a frequency ratio between the frequency of the output signal (SSP) of the main oscillator and a reference frequency of a reference signal (SRF) originating from a reference oscillator (OSCR) and a transmission phase comprising only frequency-locking the output signal (SSP) of the main oscillator onto the frequency of the reference signal corrected by said estimated ratio, the only frequency-locking not modifying the phase of the output signal (SSP) of the main oscillator, said main clock signal (SH1) originating from the output signal (SSP) of the main oscillator.