mhurhangee/patent-ind-claim-en huggingface dataset:
A compound having a structure represented by a formula: wherein m is 1; n is an integer from 0 to 3; Z is independently selected from N and CH; R 1 is selected from halo, C1-C3 haloalkyl, and C1-C3 polyhaloalkyl; each of R 2 , R 3 , and R 4 is independently selected from hydrogen, halo, hydroxyl, cyano, amino, C2-C6 alkalkoxy, C1-C6 alkoxy, C1-C6 alkyl, C1-C6 polyhaloalkyl, and C1-C6 haloalkyl; R 5 is selected from NR 6 R 7 and Cy, and substituted with 0-3 groups independently selected from halo, hydroxyl, amino, C2-C6 alkalkoxy, C1-C6 alkylalcohol, C1-C6 alkoxy, C1-C6 alkyl, C1-C6 polyhaloalkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, and Cy; Cy is a heterocycloalkyl selected from aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, azepanyl, oxazolidinyl, imidazolidinyl, pyrazolidinyl, piperazinyl, oxazinanyl, morpholinyl, hexahydrophyrimidinyl, and hexahydropyridazinyl; and each of R 6 and R 7 is independently selected from hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl, and C3-C6 heterocycloalkyl; or a pharmaceutically acceptable salt thereof. m is 1; n is an integer from 0 to 3; Z is independently selected from N and CH; R 1 is selected from halo, C1-C3 haloalkyl, and C1-C3 polyhaloalkyl; each of R 2 , R 3 , and R 4 is independently selected from hydrogen, halo, hydroxyl, cyano, amino, C2-C6 alkalkoxy, C1-C6 alkoxy, C1-C6 alkyl, C1-C6 polyhaloalkyl, and C1-C6 haloalkyl; R 5 is selected from NR 6 R 7 and Cy, and substituted with 0-3 groups independently selected from halo, hydroxyl, amino, C2-C6 alkalkoxy, C1-C6 alkylalcohol, C1-C6 alkoxy, C1-C6 alkyl, C1-C6 polyhaloalkyl, C1-C6 haloalkyl, C3-C6 cycloalkyl, and Cy; Cy is a heterocycloalkyl selected from aziridinyl, azetidinyl, pyrrolidinyl, piperidinyl, azepanyl, oxazolidinyl, imidazolidinyl, pyrazolidinyl, piperazinyl, oxazinanyl, morpholinyl, hexahydrophyrimidinyl, and hexahydropyridazinyl; and each of R 6 and R 7 is independently selected from hydrogen, C1-C6 alkyl, C3-C6 cycloalkyl, and C3-C6 heterocycloalkyl;
An assay for identifying a bacterium capable of binding elemental gold and/or silver, comprising the following steps: (i) cultivating a test bacterium in a suitable first culture medium; (ii) immersing at least a surface portion of a test tool into the first culture medium for a second predetermined period of time, said surface portion being coated by the elemental gold and/or silver, respectively; (iii) removing said test tool from said first culture medium; (iv) contacting a second culture medium with the surface portion coated by the elemental gold and/or silver of said test tool removed in the previous step for inoculating the second culture medium with any test bacteria adhering to the surface portion of the test tool; and (v) identifying the test bacterium as being capable of binding the elemental gold and/or silver from growth of the test bacterium in said second culture medium. (i) cultivating a test bacterium in a suitable first culture medium; (ii) immersing at least a surface portion of a test tool into the first culture medium for a second predetermined period of time, said surface portion being coated by the elemental gold and/or silver, respectively; (iii) removing said test tool from said first culture medium; (iv) contacting a second culture medium with the surface portion coated by the elemental gold and/or silver of said test tool removed in the previous step for inoculating the second culture medium with any test bacteria adhering to the surface portion of the test tool; and (v) identifying the test bacterium as being capable of binding the elemental gold and/or silver from growth of the test bacterium in said second culture medium.
A plunger pump that is capable of drawing in a liquid from an inlet flow path (R1) and delivering the liquid to an outlet flow path (R2) at a predetermined pressure, the plunger pump comprising: a tubular cylinder that has an internal space communicating with the inlet flow path (R1) and the outlet flow path (R2); and a piston that is movable along an axis (O) of the cylinder , wherein a head of the piston is provided, on an outer peripheral surface thereof, with a sealing portion that is slidable against an inner peripheral surface of the cylinder , characterized by that the cylinder includes a body tubular portion in which the head is arranged during normal use, and a cleaning tubular portion in which the head is arranged during cleaning, an inner peripheral surface of the cleaning tubular portion has an inner diameter equal to an inner diameter of an inner peripheral surface of the body tubular portion , the cleaning tubular portion is provided, on the inner peripheral surface thereof, with at least one cleaning liquid circulation groove that is configured by a through hole or a recess, and the at least one cleaning liquid circulation groove extends obliquely with respect to the axis (O). a tubular cylinder that has an internal space communicating with the inlet flow path (R1) and the outlet flow path (R2); and a piston that is movable along an axis (O) of the cylinder , wherein a head of the piston is provided, on an outer peripheral surface thereof, with a sealing portion that is slidable against an inner peripheral surface of the cylinder , characterized by that the cylinder includes a body tubular portion in which the head is arranged during normal use, and a cleaning tubular portion in which the head is arranged during cleaning, an inner peripheral surface of the cleaning tubular portion has an inner diameter equal to an inner diameter of an inner peripheral surface of the body tubular portion , the cleaning tubular portion is provided, on the inner peripheral surface thereof, with at least one cleaning liquid circulation groove that is configured by a through hole or a recess, and the at least one cleaning liquid circulation groove extends obliquely with respect to the axis (O).
A hand-guided light hardening device, comprising a light source which is arranged in the hand-guided light hardening device, having at least one sensor which is sensitive to light in the emission wavelength range of the light source, having a light guide, at the distal end of which a light emission surface is provided and having a control device for controlling the light source during polymerization of the dental material, to which control device the sensor is connected, wherein the control device has more than one light sensor and continuously or at least recurrently monitors the output signal of each sensor during the polymerization of the dental material and, in the event of a change, in particular reduction of the output signal, adjusts the light power and/or adjusts the polymerization time, and in that the control device uses the reflection radiation detected via the light exit surface and/or the change thereof for calculating any positional deviation of the light hardening unit in relation to a dental restoration , in which a part of the light energy emitted via the light-emitting surface is summed up laterally next to a tooth comprising the dental restoration , i.e. falling into an oral cavity, and in that the light source has at least one reflector, the sensors being arranged outside the at least one reflector next thereto, in particular being shifted thereto maximally close.
Tool for closing an opening of a container by a closure , the container comprising a container wall having a container interior , the tool comprising : (a) a tool plate which is insertable into an opening of a container to be closed; (b) at least one roller arranged on the tool plate in an initial position , (c) wherein the at least one roller can be deflected radially into a closing position and can be returned to its starting position in order to make or exert a radial force, limited in time, on a closing collar of the closure arranged between the at least one roller and the container inner side of the container wall; and characterised in that (d) the at least one roller is connected to the tool plate via an extension arm and a joint , and wherein the at least one roller is connected along its longitudinal axis to a roller axle which is connected to a rod via a connecting element , and wherein the rod can be extended and retracted by a lifting device . (a) a tool plate which is insertable into an opening of a container to be closed; (b) at least one roller arranged on the tool plate in an initial position , (c) wherein the at least one roller can be deflected radially into a closing position and can be returned to its starting position in order to make or exert a radial force, limited in time, on a closing collar of the closure arranged between the at least one roller and the container inner side of the container wall; and characterised in that (d) the at least one roller is connected to the tool plate via an extension arm and a joint , and wherein the at least one roller is connected along its longitudinal axis to a roller axle which is connected to a rod via a connecting element , and wherein the rod can be extended and retracted by a lifting device .
A torque sensor including a first region coupled to a first mechanism, a second region coupled to a second mechanism, and a plurality of third regions connecting the first region and the second region , a torque to be measured being transmitted between the first region and the second region via the third region, the torque sensor comprising: a first strain generation part comprising a first end , a second end , and a first intermediate portion between the first end and the second end, the first end being provided on the first region , the first intermediate portion being provided on the second region ; a second strain generation part comprising a third end , a fourth end , and a second intermediate portion between the third end and the fourth end, the third end being provided on the first region , the second intermediate portion being provided on the second region , the fourth end being arranged near the second end of the first strain generation part , characterized in that ; the second end of the first strain generation part is opposed to and spaced apart in a predetermined interval from the fourth end of the second strain generation part ; and a strain body connecting the second end of the first strain generation part and the fourth end of the second strain generation part and being provided with a resistor. a first strain generation part comprising a first end , a second end , and a first intermediate portion between the first end and the second end, the first end being provided on the first region , the first intermediate portion being provided on the second region ; a second strain generation part comprising a third end , a fourth end , and a second intermediate portion between the third end and the fourth end, the third end being provided on the first region , the second intermediate portion being provided on the second region , the fourth end being arranged near the second end of the first strain generation part , characterized in that ; the second end of the first strain generation part is opposed to and spaced apart in a predetermined interval from the fourth end of the second strain generation part ; and a strain body connecting the second end of the first strain generation part and the fourth end of the second strain generation part and being provided with a resistor.
Antimicrobial expandable polystyrene (EPS) beads, comprising as main antimicrobial agent silver ions, wherein the silver ions are deposited on the surface of the beads in the form of a metal salt of a fatty acid.
A photoprotective composition comprising a nanoparticle comprising oil and UV filter; wherein the nanoparticle is a polymeric nanoparticle; wherein the oil is buriti oil; wherein the UV filter comprises octocrylene and avobenzone; and further a physiologically acceptable excipient or a cosmetic auxiliary, or a combination thereof. a nanoparticle comprising oil and UV filter; wherein the nanoparticle is a polymeric nanoparticle; wherein the oil is buriti oil; wherein the UV filter comprises octocrylene and avobenzone; and further a physiologically acceptable excipient or a cosmetic auxiliary, or a combination thereof.
Apparatus , comprising: an insertion tube having a distal end configured for insertion into proximity with tissue in a body of a patient and containing a lumen comprising an electrical conductor for conveying electrical energy to the tissue; a conductive cap attached to the distal end of the insertion tube and coupled electrically to the electrical conductor, wherein the conductive cap has an outer surface; a multiplicity of optical fibers contained within the insertion tube , each fiber terminating in proximity to the outer surface of the cap , characterized in that each fiber is configured to convey optical radiation to and from the tissue while the electrical energy is being conveyed to the tissue and in that the apparatus further comprises an optical module configured to determine contact of the conductive cap with the tissue in response to measuring a first level of the optical radiation conveyed via a given optical fiber (118; 128) to the tissue and a second level of the optical radiation conveyed via the given optical fiber (118; 128) from the tissue. an insertion tube having a distal end configured for insertion into proximity with tissue in a body of a patient and containing a lumen comprising an electrical conductor for conveying electrical energy to the tissue; a conductive cap attached to the distal end of the insertion tube and coupled electrically to the electrical conductor, wherein the conductive cap has an outer surface; a multiplicity of optical fibers contained within the insertion tube , each fiber terminating in proximity to the outer surface of the cap , characterized in that each fiber is configured to convey optical radiation to and from the tissue while the electrical energy is being conveyed to the tissue and in that the apparatus further comprises an optical module configured to determine contact of the conductive cap with the tissue in response to measuring a first level of the optical radiation conveyed via a given optical fiber (118; 128) to the tissue and a second level of the optical radiation conveyed via the given optical fiber (118; 128) from the tissue.
A compound having a structure according to Formula II: wherein R 1 is selected from the group consisting of phenyl, biphenyl, terphenyl, tetraphenyl, pentaphenyl, pyridine, phenyl pyridine and pyridyl phenyl; wherein R 4 is selected from the group consisting of phenyl, pyridyl, biphenyl, and terphenyl; wherein R 5 is selected from the group consisting of phenyl, pyridyl, biphenyl, and terphenyl; wherein R 2 and R 3 can be same or different, and independently selected from the group consisting of hydrogen, deuterium, non-fused aryl, non-fused heteroaryl and combinations thereof; wherein L is selected from the group consisting of phenyl, pyridyl, biphenyl, terphenyl and a bond; and wherein Y 1 is N. wherein R 1 is selected from the group consisting of phenyl, biphenyl, terphenyl, tetraphenyl, pentaphenyl, pyridine, phenyl pyridine and pyridyl phenyl; wherein R 4 is selected from the group consisting of phenyl, pyridyl, biphenyl, and terphenyl; wherein R 5 is selected from the group consisting of phenyl, pyridyl, biphenyl, and terphenyl; wherein R 2 and R 3 can be same or different, and independently selected from the group consisting of hydrogen, deuterium, non-fused aryl, non-fused heteroaryl and combinations thereof; wherein L is selected from the group consisting of phenyl, pyridyl, biphenyl, terphenyl and a bond; and wherein Y 1 is N.
Articulated-arm robot having a serial kinematic mechanism for positioning an end effector , wherein the kinematic mechanism has at least one part kinematic mechanism with a robot joint (6.1), with a robot member (6.2) mounted upstream of the robot joint (6.1), and with a robot member (6.3) mounted downstream of the robot joint (6.1), wherein the at least one part kinematic mechanism , for adjusting the robot members (6.2, 6.3) in relation to one another, has a linear drive (6.4) with a drive element (6.6) able to be adjusted along a linear axis (6.5) and has a coupler (6.7) with two coupler joints (6.8, 6.9) which are spaced apart from one another along the coupler extent, wherein the linear drive (6.4) is arranged on a first robot member (6.10) of the part kinematic mechanism , wherein the coupler (6.7) is articulated on the drive element (6.6) of the linear drive (6.4) at one side and on the second, remaining robot member (6.11) of the part kinematic mechanism at the other side so as to be spaced apart from the geometrical axis (6.1a) of the robot joint (6.1) of the part kinematic mechanism , and wherein, on the first robot member (6.10) of the part kinematic mechanism , there is arranged separately from the linear drive (6.4) a longitudinal guide (6.16) by means of which the drive element (6.6) is guided longitudinally in a guide direction (6.17) on the first robot member (6.10). wherein the at least one part kinematic mechanism , for adjusting the robot members (6.2, 6.3) in relation to one another, has a linear drive (6.4) with a drive element (6.6) able to be adjusted along a linear axis (6.5) and has a coupler (6.7) with two coupler joints (6.8, 6.9) which are spaced apart from one another along the coupler extent, wherein the linear drive (6.4) is arranged on a first robot member (6.10) of the part kinematic mechanism , wherein the coupler (6.7) is articulated on the drive element (6.6) of the linear drive (6.4) at one side and on the second, remaining robot member (6.11) of the part kinematic mechanism at the other side so as to be spaced apart from the geometrical axis (6.1a) of the robot joint (6.1) of the part kinematic mechanism , and wherein, on the first robot member (6.10) of the part kinematic mechanism , there is arranged separately from the linear drive (6.4) a longitudinal guide (6.16) by means of which the drive element (6.6) is guided longitudinally in a guide direction (6.17) on the first robot member (6.10).
A functional material comprising: a porous metal-organic framework (MOF) including an organic ligand derived from benzenedicarboxylic acid and a metal ion cluster coordination-bonded with the organic ligand; and a luminescent molecule in pores of the MOF; wherein the functional material further comprises trialkylammonium ions in the pores of the MOF, wherein the trialkylammonium ions are trimethylammonium ions or triethylammonium ions. a porous metal-organic framework (MOF) including an organic ligand derived from benzenedicarboxylic acid and a metal ion cluster coordination-bonded with the organic ligand; and a luminescent molecule in pores of the MOF; wherein the functional material further comprises trialkylammonium ions in the pores of the MOF, wherein the trialkylammonium ions are trimethylammonium ions or triethylammonium ions.
Operating element , comprising: an actuating lever which is mounted pivotably about a first pivot axis and a second pivot axis which is orthogonal with respect to the first pivot axis , with a section which faces the operator with regard to the first pivot axis , and with an operating lever section which faces away from the operator; a driver lever which is mounted such that it can be pivoted about a driver pivot axis along a pivoting direction ; a first magnet , preferably a permanent magnet, which is fastened rigidly to the driver lever , a plurality of stationary, second magnets , preferably permanent magnets, which are arranged in such a way that the first magnet crosses the magnetic fields of the second magnet during pivoting of the driver lever , in order to generate haptic feedback at the actuating lever ; a first operating engagement means between the actuating lever section and the driver lever being provided, in order to bring about synchronous pivoting of the actuating lever and the driver lever , characterized in that the driver lever is mounted such that it can be moved perpendicularly with respect to its pivoting direction , in order, by means of the first operative engagement means or by means of a second operative engagement means between the actuating lever section and the driver lever , to bring about a synchronous movement of the driver lever by way of pivoting of the actuating lever about the second pivot axis . an actuating lever which is mounted pivotably about a first pivot axis and a second pivot axis which is orthogonal with respect to the first pivot axis , with a section which faces the operator with regard to the first pivot axis , and with an operating lever section which faces away from the operator; a driver lever which is mounted such that it can be pivoted about a driver pivot axis along a pivoting direction ; a first magnet , preferably a permanent magnet, which is fastened rigidly to the driver lever , a plurality of stationary, second magnets , preferably permanent magnets, which are arranged in such a way that the first magnet crosses the magnetic fields of the second magnet during pivoting of the driver lever , in order to generate haptic feedback at the actuating lever ; a first operating engagement means between the actuating lever section and the driver lever being provided, in order to bring about synchronous pivoting of the actuating lever and the driver lever , characterized in that the driver lever is mounted such that it can be moved perpendicularly with respect to its pivoting direction , in order, by means of the first operative engagement means or by means of a second operative engagement means between the actuating lever section and the driver lever , to bring about a synchronous movement of the driver lever by way of pivoting of the actuating lever about the second pivot axis .