mhurhangee/patent-ind-claim-en huggingface dataset:
A method comprising (a) contacting a fusion protein comprising a polypeptide and a split intein N-fragment comprising a sequence selected from the group consisting of SEQ ID NO: 1-19, or a variant thereof, wherein the variant consists of a sequence selected from the group consisting of SEQ ID NO: 21-38 and 761 and a split intein C-fragment comprising a sequence selected from the group consisting of SEQ ID NO: 57-74 and 708 or a variant thereof, wherein the variant consists of a sequence selected from the group consisting of SEQ ID NO: 75-128, 707 and 709-711, wherein contacting is performed under conditions that permit binding of the split intein N-fragment to the split intein C-fragment to form an intein intermediate; and (b) contacting the intein intermediate with a nucleophile to form a conjugate of the protein and the nucleophile. (a) contacting a fusion protein comprising a polypeptide and a split intein N-fragment comprising a sequence selected from the group consisting of SEQ ID NO: 1-19, or a variant thereof, wherein the variant consists of a sequence selected from the group consisting of SEQ ID NO: 21-38 and 761 and a split intein C-fragment comprising a sequence selected from the group consisting of SEQ ID NO: 57-74 and 708 or a variant thereof, wherein the variant consists of a sequence selected from the group consisting of SEQ ID NO: 75-128, 707 and 709-711, wherein contacting is performed under conditions that permit binding of the split intein N-fragment to the split intein C-fragment to form an intein intermediate; and (b) contacting the intein intermediate with a nucleophile to form a conjugate of the protein and the nucleophile.
Method for operating a ventilation device, the ventilation device having a radial fan for conveying air, which has a radial fan rotor and an electronically commutated electric motor for driving the radial fan rotor and has a fan characteristic curve according to which the radial fan effects a specific pressure difference (Δp) across the radial fan at a specific volumetric flow (V) conveyed by the radial fan, wherein in constant operation of the radial fan with at least one constant operating parameter a constant operation characteristic curve is present and a maximum pressure difference (Δp max ) results at a minimum volumetric flow and a maximum volumetric flow (V max ) results at a minimum pressure difference, wherein a power consumption of the electric motor and/or a current consumption of the electric motor and/or a rotational speed of the electric motor and/or a duty cycle for pulse-width modulated control of the radial fan is used as the constant operating parameter, the radial fan being operated in at least one operating mode by changing the fan characteristic curve in such a way that the fan characteristic curve differs from the constant operation characteristic curve, so that a limiting pressure difference which is present at minimum volumetric flow is smaller than the maximum pressure difference (Δ pmax ), characterized in that , in the at least one operating mode, in the case of a pressure difference between the minimum pressure difference and an intermediate pressure difference, an actual volumetric flow conveyed by the radial fan is regulated to a setpoint volumetric flow using the rotational speed of the electric motor as a control variable and, in the case of a pressure difference between the intermediate pressure difference and the maximum pressure difference, with the pressure difference increasing starting from the intermediate pressure difference, the rotational speed is kept constant or is reduced so that the limiting pressure difference is smaller than the maximum pressure difference.
A machine for treating a concrete surface comprising: - a tool for treating a concrete surface mechanically coupled to one end of a telescopic mechanical arm , so that the tool is movable over the concrete surface along a direction of extension (d) of the arm ; - a hollow compartment for the arm ; - wheels coupled to the compartment and arranged to move the machine ; characterized in that: - the compartment is formed in a chassis of the machine extending mainly along the direction of extension (d); - the chassis comprises two end segments at the level of each of which is attached at least one axle extending transversely to the direction of extension (d) and supporting at least one of the wheels ; - the wheels are orientable and adapted to support the machine for any position of the tool along the extension direction (d). - a tool for treating a concrete surface mechanically coupled to one end of a telescopic mechanical arm , so that the tool is movable over the concrete surface along a direction of extension (d) of the arm ; - a hollow compartment for the arm ; - wheels coupled to the compartment and arranged to move the machine ; - the compartment is formed in a chassis of the machine extending mainly along the direction of extension (d); - the chassis comprises two end segments at the level of each of which is attached at least one axle extending transversely to the direction of extension (d) and supporting at least one of the wheels ; - the wheels are orientable and adapted to support the machine for any position of the tool along the extension direction (d).
An in vitro method for diagnosing or identifying pancreas cancer in a subject, said method comprising determining the level or amount of methylation of the POU4F1 gene or of the HOXD8 gene in a body effluent of said subject.
A clustered Single-Carrier Frequency Division Multiple Access, SC-FDMA, receiving apparatus comprising: a receiving section configured to receive, from a clustered SC-FDMA transmitting apparatus, signals that are mapped on a plurality of discontinuous frequency bands in a frequency domain, the signals being generated by dividing an output of a single DFT section of the clustered SC-FDMA transmitting apparatus; a combiner configured to combine the received signals mapped on the plurality of discontinuous frequency bands in the frequency domain into a combined signal; and a transforming section configured to transform the combined signal in the frequency domain into a symbol in a time domain by performing an inverse discrete Fourier transformation, IDFT, on the combined signal in the frequency domain, characterized in that a vector length, corresponding to a size of at least one of the plurality of discontinuous frequency bands, is a multiple of a product of two or more powers of prime numbers, each prime number being equal to or larger than two, and the two or more prime numbers being different from each other, the vector length being a number of subcarriers allocated to the at least one of the plurality of discontinuous frequency bands; and the IDFT is performed using an IDFT matrix with an IDFT size which is a product of powers of a plurality of values, wherein the vector length is a partially orthogonal vector length of column vectors constituting the IDFT matrix. a receiving section configured to receive, from a clustered SC-FDMA transmitting apparatus, signals that are mapped on a plurality of discontinuous frequency bands in a frequency domain, the signals being generated by dividing an output of a single DFT section of the clustered SC-FDMA transmitting apparatus; a combiner configured to combine the received signals mapped on the plurality of discontinuous frequency bands in the frequency domain into a combined signal; and a transforming section configured to transform the combined signal in the frequency domain into a symbol in a time domain by performing an inverse discrete Fourier transformation, IDFT, on the combined signal in the frequency domain, characterized in that a vector length, corresponding to a size of at least one of the plurality of discontinuous frequency bands, is a multiple of a product of two or more powers of prime numbers, each prime number being equal to or larger than two, and the two or more prime numbers being different from each other, the vector length being a number of subcarriers allocated to the at least one of the plurality of discontinuous frequency bands; and the IDFT is performed using an IDFT matrix with an IDFT size which is a product of powers of a plurality of values, wherein the vector length is a partially orthogonal vector length of column vectors constituting the IDFT matrix.
Planetary gearing , comprising an internal gear holder and an internal gear for receiving at least one planet gear , wherein the internal gear holder can be connected at a face side to a housing component , and a plurality of cutouts for receiving fastening means is formed at a face side of the internal gear holder , characterized in that , in at least one of the cutouts , there is received a hollow element in which a screw is received as a fastening means , wherein the hollow element establishes a form fit between the internal gear holder and the housing component , and the at least one cutout with the hollow element received therein and with the screw is arranged in a region of a torque support , the at least one cutout being formed in the internal gear holder and/or in the housing component as a bore with a first and a second bore diameter .
Process for the cosmetic treatment of the skin comprising applying to the affected skin diathermy along with a conductive gel and one or more oils and/or another substance selected from the group consisting of hyaluronic acid, shea butter, aloe vera and vitamins, or a combination thereof, wherein the conductive gel is applied with diathermy in resistive mode and the oil or oils are applied with diathermy in capacitive mode.
A multicylinder internal combustion engine comprising a rotational speed estimating device estimating a rotational speed N of a rotating body having a plurality of blades based on an output value of a detecting part detecting passage of a blade of the rotating body over a predetermined position inside a housing holding the rotating body, the rotational speed estimating device configured to: acquire an output value of the detecting part at a predetermined sampling period; calculate as a reference blade passage time t m an elapsed time t e from when any one blade among the plurality of blades passes the predetermined position once each time the any one blade passes the predetermined position a predetermined number of times; estimate the rotational speed N of the rotating body based on the reference blade passage time t m and the number of times the any one blade passes the predetermined position during the reference blade passage time when the reference blade passage time t m is a threshold value t thres characterized in that the threshold value t thres is preset based on the sampling period t smp so that the sampling error E is not more than a predetermined allowable error E allow , or more; and the rotational speed estimating device is configured to decrease the threshold value t thres as an engine rotational speed N of the multicylinder internal combustion engine increases. acquire an output value of the detecting part at a predetermined sampling period; calculate as a reference blade passage time t m an elapsed time t e from when any one blade among the plurality of blades passes the predetermined position once each time the any one blade passes the predetermined position a predetermined number of times; estimate the rotational speed N of the rotating body based on the reference blade passage time t m and the number of times the any one blade passes the predetermined position during the reference blade passage time when the reference blade passage time t m is a threshold value t thres characterized in that the threshold value t thres is preset based on the sampling period t smp so that the sampling error E is not more than a predetermined allowable error E allow , or more; and the rotational speed estimating device is configured to decrease the threshold value t thres as an engine rotational speed N of the multicylinder internal combustion engine increases.
Method for detecting a tool malpositioning of a sealing tool arranged in a packaging machine , characterized in that at least two tokens are disposed at the sealing tool in such a way that in a first operating position of the sealing tool , their respective presence is detectable by corresponding sensors of the packaging machine and is not detectable in a second operating position, the method comprising: Detecting a first signal from a first one of the at least two sensors , the first signal indicating the presence of a first one of the at least two tokens , Detecting a second signal from a second one of the at least two sensors , the second signal indicating the presence of a second one of the at least two tokens (19a, 19b, Monitoring the first and the second signal, Detecting a first signal loss of one of the first and second signals, Capturing a time span, which elapsed after the first signal loss, Determining a tool malpositioning once the captured elapsed time span exceeds a predetermined value. Detecting a first signal from a first one of the at least two sensors , the first signal indicating the presence of a first one of the at least two tokens , Detecting a second signal from a second one of the at least two sensors , the second signal indicating the presence of a second one of the at least two tokens (19a, 19b, Monitoring the first and the second signal, Detecting a first signal loss of one of the first and second signals, Capturing a time span, which elapsed after the first signal loss, Determining a tool malpositioning once the captured elapsed time span exceeds a predetermined value.
A tensioner for an accessory drive of a motor vehicle provided with an internal combustion engine and a reversible electric machine acting as motor and generator, the drive comprising at least a first pulley mounted on a drive shaft of the internal combustion engine , a second pulley mounted on the shaft of the electric machine and an endless drive element cooperating with at least said first pulley and said second pulley , the tensioner comprising a support element adapted to be fixed on or close to the electric machine , characterized by including: an intermediate element carried by the support element and rotating with respect thereto about a first fixed axis (A); a rigid tensioner element rotating with respect to the intermediate element about a second axis (B) parallel to the first axis (A) and distinct therefrom; a first and a second tensioning pulley carried by the tensioner element and rotating with respect thereto about respective axes distinct from said first and second axis (A, B) and arranged in use in a fixed relative position, and at least one spring acting between the support element and the intermediate element to push the pulleys into contact with respective branches of the endless drive element positioned on opposite sides with respect to the second pulley . an intermediate element carried by the support element and rotating with respect thereto about a first fixed axis (A); a rigid tensioner element rotating with respect to the intermediate element about a second axis (B) parallel to the first axis (A) and distinct therefrom; a first and a second tensioning pulley carried by the tensioner element and rotating with respect thereto about respective axes distinct from said first and second axis (A, B) and arranged in use in a fixed relative position, and at least one spring acting between the support element and the intermediate element to push the pulleys into contact with respective branches of the endless drive element positioned on opposite sides with respect to the second pulley .
Aeroplane comprising at least one fuselage , two wings , a tail unit comprising a horizontal stabilizer provided with two stabilizer ends , and at least two engines arranged on the fuselage on either side of a vertical plane (XZ) of symmetry of the aeroplane , said aeroplane having a longitudinal axis (L), characterized in that said engines are mounted such that they can be moved, at least in flight, on said fuselage , essentially parallel to the longitudinal axis (L), between a "forward" position (P1) and a "rear" position (P2), and in that said stabilizer ends are mounted such that they can be pivoted, at least in flight, relative to said horizontal stabilizer .
A waste sorting robot comprising: a manipulator comprising a suction gripper for interacting with one or more waste objects to be sorted within a working area , wherein the manipulator is moveable within the working area and wherein the suction gripper is moveable relative to the manipulator between a first position being a start position and a second position in which the suction gripper engages a waste object; a controller configured to send control instructions to the manipulator ; and at least one sensor configured to detect the suction gripper moving between the first and second positions, whereby the controller is configured to determine the suction gripper has engaged a waste object; characterized in that the controller is configured to actuate the suction gripper in dependence on a signal detecting the suction gripper has moved between the first and second positions so that suction in the suction gripper is turned on in the second position. a manipulator comprising a suction gripper for interacting with one or more waste objects to be sorted within a working area , wherein the manipulator is moveable within the working area and wherein the suction gripper is moveable relative to the manipulator between a first position being a start position and a second position in which the suction gripper engages a waste object; a controller configured to send control instructions to the manipulator ; and at least one sensor configured to detect the suction gripper moving between the first and second positions, whereby the controller is configured to determine the suction gripper has engaged a waste object; characterized in that the controller is configured to actuate the suction gripper in dependence on a signal detecting the suction gripper has moved between the first and second positions so that suction in the suction gripper is turned on in the second position.
A machine for producing a filled foodstuff product, comprising: - a first container for receiving a first foodstuff material; - a second container for receiving a second foodstuff material or else a connection unit for connecting a second container, containing the second material, to the machine; - a dispensing unit comprising at least one dispensing nozzle , in which the dispensing nozzle comprises a first outlet and a second outlet that is external to the first outlet and surrounds it; - at least one valve unit for controlling a flow of the first material to the first outlet and a flow of the second material to the second outlet ; - a control unit for controlling the at least one valve unit for providing, one at a time or simultaneously, a flow of material through the first outlet and a flow of material through the second outlet ; the machine being characterized in that it comprises a cooling unit for cooling an inner surface (S) of the first container so as to cool or refrigerate the first material. - a first container for receiving a first foodstuff material; - a second container for receiving a second foodstuff material or else a connection unit for connecting a second container, containing the second material, to the machine; - a dispensing unit comprising at least one dispensing nozzle , in which the dispensing nozzle comprises a first outlet and a second outlet that is external to the first outlet and surrounds it; - at least one valve unit for controlling a flow of the first material to the first outlet and a flow of the second material to the second outlet ; - a control unit for controlling the at least one valve unit for providing, one at a time or simultaneously, a flow of material through the first outlet and a flow of material through the second outlet ; the machine being characterized in that it comprises a cooling unit for cooling an inner surface (S) of the first container so as to cool or refrigerate the first material.
A toner comprising a toner particle including a binder resin and an inorganic fine particle, wherein the inorganic fine particle includes a calcium strontium zirconate fine particle. a toner particle including a binder resin and an inorganic fine particle,
A processing apparatus comprising: - a non-contact power supply device ; - a closed container ; - a moving unit provided inside the closed container so as to be movable inside the closed container , wherein the non-contact power supply device is configured for supplying electric power to the moving unit from outside the closed container , the non-contact power supply device comprising: a feed unit ; a heat dissipator , wherein the feed unit comprises a feed line and a power supply transformer , the feed line comprises a feed region arranged inside the closed container along the moving direction of the moving unit , the power supply transformer is arranged inside the closed container so as to be opposed to the feed region in a non-contact manner and is provided to move together with the moving unit , and the heat dissipator comprises a portion on one end side connected to the feed region so as to be capable of conducting heat thereto and a portion on the other end side extending outside the closed container . - a non-contact power supply device ; - a closed container ; - a moving unit provided inside the closed container so as to be movable inside the closed container , wherein the non-contact power supply device is configured for supplying electric power to the moving unit from outside the closed container , the non-contact power supply device comprising: a feed unit ; a heat dissipator , wherein the feed unit comprises a feed line and a power supply transformer , the feed line comprises a feed region arranged inside the closed container along the moving direction of the moving unit , the power supply transformer is arranged inside the closed container so as to be opposed to the feed region in a non-contact manner and is provided to move together with the moving unit , and the heat dissipator comprises a portion on one end side connected to the feed region so as to be capable of conducting heat thereto and a portion on the other end side extending outside the closed container . a feed unit ; a heat dissipator , wherein the feed unit comprises a feed line and a power supply transformer , the feed line comprises a feed region arranged inside the closed container along the moving direction of the moving unit , the power supply transformer is arranged inside the closed container so as to be opposed to the feed region in a non-contact manner and is provided to move together with the moving unit , and the heat dissipator comprises a portion on one end side connected to the feed region so as to be capable of conducting heat thereto and a portion on the other end side extending outside the closed container .