A device for carrying out a reaction, the device comprising: a first part having a first surface ; a plurality of first areas located along a portion of the first surface, the plurality of first areas configured to maintain at least one first substance; a second part having a second surface opposed to the first surface; and a plurality of second areas located along a portion of the second surface, the plurality of second areas configured to maintain at least one second substance, wherein at least one of the first surface of the first part and the second surface of the second part is configured to move relative to the other between a first position, where the plurality of second areas are not exposed to any of the plurality of first areas , and a second position, where at least one of the plurality of second areas is only exposed to one of the plurality of first areas , and form a closed system; and wherein there is fluid communication within said first and second parts between second areas in said first position and in the second position said fluid communication is broken, the device further comprising at least one discrete duct formed along a portion of the first surface , spaced apart from and not in communication with the plurality of first areas , wherein: when in the first position, the plurality of second areas are exposed to the at least one discrete duct to allow fluid communication between the at least one discrete duct and the second areas , when in the second position, the fluidic communication between the at least one discrete duct and the second areas is broken. a first part having a first surface ; a plurality of first areas located along a portion of the first surface, the plurality of first areas configured to maintain at least one first substance; a second part having a second surface opposed to the first surface; and a plurality of second areas located along a portion of the second surface, the plurality of second areas configured to maintain at least one second substance, wherein at least one of the first surface of the first part and the second surface of the second part is configured to move relative to the other between a first position, where the plurality of second areas are not exposed to any of the plurality of first areas , and a second position, where at least one of the plurality of second areas is only exposed to one of the plurality of first areas , and form a closed system; and wherein there is fluid communication within said first and second parts between second areas in said first position and in the second position said fluid communication is broken, the device further comprising at least one discrete duct formed along a portion of the first surface , spaced apart from and not in communication with the plurality of first areas , wherein: when in the first position, the plurality of second areas are exposed to the at least one discrete duct to allow fluid communication between the at least one discrete duct and the second areas , when in the second position, the fluidic communication between the at least one discrete duct and the second areas is broken. when in the first position, the plurality of second areas are exposed to the at least one discrete duct to allow fluid communication between the at least one discrete duct and the second areas , when in the second position, the fluidic communication between the at least one discrete duct and the second areas is broken. <EOS>