mhurhangee/ep-ind-claims huggingface dataset:
A lyophilized powder comprising mannitol and a compound of the formula: wherein P is hydrogen or an amino-group protecting moiety; R is hydrogen or C 1-12 alkyl; A is 0, 1, or 2; R 1, R 2, and R 3 are each independently hydrogen, C 1-12 alkyl, C 3-12 cycloalkyl, C 6-14 aryl, or -CH 2 -R 5; R 5, in each instance, is C 6-14 aryl, (C 6-14)ar(C 1-12)alkyl, (C 1-12)alk(C 6-14)aryl, C 3-12 cycloalkyl, heterocyclyl comprising 3 to 8 atoms, wherein one or more atoms is selected from N, O, and S, heteroaryl comprising 5 to 14 atoms, wherein 1-4 atoms are selected from N, O, and S, or -W-R 6, where W is a chalcogen and R 6 is C 1-12 alkyl; wherein the ring portion of any said aryl, aralkyl, alkaryl, cycloalkyl, heterocyclyl, or heteroaryl in R 1, R 2, R 3, or R 5 can be optionally substituted; and Z 1 and Z 2 together form a moiety derived from mannitol, wherein the atom attached to boron in each case is an oxygen atom, and wherein the compound of formula is lyophilized and wherein said compound is a mannitol ester of N -(2-pyrazine)carbonyl-L-phenylalanine-L-leucine boronic acid. P is hydrogen or an amino-group protecting moiety; R is hydrogen or C 1-12 alkyl; A is 0, 1, or 2; R 1, R 2, and R 3 are each independently hydrogen, C 1-12 alkyl, C 3-12 cycloalkyl, C 6-14 aryl, or -CH 2 -R 5; R 5, in each instance, is C 6-14 aryl, (C 6-14)ar(C 1-12)alkyl, (C 1-12)alk(C 6-14)aryl, C 3-12 cycloalkyl, heterocyclyl comprising 3 to 8 atoms, wherein one or more atoms is selected from N, O, and S, heteroaryl comprising 5 to 14 atoms, wherein 1-4 atoms are selected from N, O, and S, or -W-R 6, where W is a chalcogen and R 6 is C 1-12 alkyl; wherein the ring portion of any said aryl, aralkyl, alkaryl, cycloalkyl, heterocyclyl, or heteroaryl in R 1, R 2, R 3, or R 5 can be optionally substituted; and Z 1 and Z 2 together form a moiety derived from mannitol, wherein the atom attached to boron in each case is an oxygen atom, and wherein the compound of formula is lyophilized and wherein said compound is a mannitol ester of N -(2-pyrazine)carbonyl-L-phenylalanine-L-leucine boronic acid.
Charging station for an electric vehicle, comprising: - a charging plug for charging the electric vehicle; - a media plug that is connectable to the electric vehicle for removing heat from a vehicle-side temperature control circuit of the electric vehicle using a cooling medium that can be supplied and removed by means of the media plug; wherein heat can also be supplied to the electric vehicle by means of the media plug using a heating medium that can be supplied and removed by means of the media plug, the charging station has a control unit which is coupled to different vehicle-side sensors and sensors external to the vehicle, and the control unit is designed to remove heat from the temperature control circuit or supply heat to the temperature control circuit depending on corresponding sensor data with respect to an outside temperature and a temperature of at least one component of the electric vehicle which is thermally coupled to the temperature control circuit, characterised in that the charging station has at least one interface for connecting the charging station to a heat supplier and at least one interface for connecting the charging station to a cold supplier, wherein waste heat is additionally also used initially during the charging process to the extent necessary and required for heating an interior of the electric vehicle, wherein excess waste heat is only removed from the battery via the charging station to the corresponding heat or cold supplier (8, 9) when the vehicle interior has been sufficiently temperature-controlled. - a charging plug for charging the electric vehicle; - a media plug that is connectable to the electric vehicle for removing heat from a vehicle-side temperature control circuit of the electric vehicle using a cooling medium that can be supplied and removed by means of the media plug;
A method for manufacturing a block of an infrastructure of a feeder for a glassmaking furnace comprising an infrastructure comprising a block self-cast in situ and sintered in situ, said method comprising the following steps: a) preparation of a self-castable unshaped product, activated and degassed under partial vacuum, b) preparation, at the place where said block is intended to be used, of a mold corresponding to the shape of said block, c) bottom feed of the mold, with removal of bubbles located at the surface of said self-castable unshaped product, activated, degassed and introduced into said mold, corresponding to the surface of said block intended to come into contact with molten glass; d) hardening of said self-castable unshaped product, activated, degassed and introduced into said mold in order to form a preform; e) optionally, mold release of said preform; f) heating-up in order to dry and sinter said preform. a) preparation of a self-castable unshaped product, activated and degassed under partial vacuum, b) preparation, at the place where said block is intended to be used, of a mold corresponding to the shape of said block, c) bottom feed of the mold, with removal of bubbles located at the surface of said self-castable unshaped product, activated, degassed and introduced into said mold, corresponding to the surface of said block intended to come into contact with molten glass; d) hardening of said self-castable unshaped product, activated, degassed and introduced into said mold in order to form a preform; e) optionally, mold release of said preform; f) heating-up in order to dry and sinter said preform.
Method for producing a tissue construct containing viable cells in an extracellular matrix, in which a matrix material and cells are molded by means of a rotary casting method in a hollow mold to give an, in particular, tubular hollow body, having the following steps: (a) introducing cells (120, 120a, 120b, 120c) of at least one cell type and a fibrinogen preparation with the aid of an applicator into the rotating hollow mold, wherein the applicator during the introduction is shifted along the axis of rotation and wherein step (a) is carried out once or several times; (b) continuing the rotary process up to solidification of the fibrinogen to form a dimensionally stable matrix, obtaining a primary-solidified tissue construct; (c) demolding the tissue construct. (a) introducing cells (120, 120a, 120b, 120c) of at least one cell type and a fibrinogen preparation with the aid of an applicator into the rotating hollow mold, wherein the applicator during the introduction is shifted along the axis of rotation and wherein step (a) is carried out once or several times; (b) continuing the rotary process up to solidification of the fibrinogen to form a dimensionally stable matrix, obtaining a primary-solidified tissue construct; (c) demolding the tissue construct.
Connector part for an optical connector comprising - a pin holder, - at least two pin sleeves (3, 3') accommodated in the pin holder, in each of which a plug pin (4, 4') with an optical waveguide is fixed, - a plug housing which is connected to the pin holder, which completely or partially surrounds the plug pins and which has latching means for creating a latching connection with a mating plug part, - wherein the pin holder consists of two half shells (12, 12') which can be latched together or are latched together, - and wherein the connector housing also can be latched to the pin holder or is latched to the pin holder, characterised by a release slide mounted on the plug housing for releasing the latching connection with the mating plug part. - a pin holder, - at least two pin sleeves (3, 3') accommodated in the pin holder, in each of which a plug pin (4, 4') with an optical waveguide is fixed, - a plug housing which is connected to the pin holder, which completely or partially surrounds the plug pins and which has latching means for creating a latching connection with a mating plug part, - wherein the pin holder consists of two half shells (12, 12') which can be latched together or are latched together, - and wherein the connector housing also can be latched to the pin holder or is latched to the pin holder,
A cushion for providing a sealed interface between a face of a person and a frame of a respiratory mask system for delivery of a supply of air at positive pressure to the entrance of the airways of the person, the cushion comprising a sealing portion including: a nasal bridge portion adapted to form a seal on the nasal bridge of the person; a side of nose region; at least one lateral stabilising portion adapted to provide a force in use on a side of the person's nose in the region of the nasal bridge of the person; a corner of mouth region; and a lower lip region; the cushion further comprising a retention feature adapted to interlock with the frame; a wall portion located between the retention feature of the cushion and the sealing portion, the wall portion having a first cross-sectional profile in the corner of mouth region, and a second cross-sectional profile in the side of nose region, wherein the sealing portion is supported along the sides of the person's nose, and characterized by that the sealing portion is substantially unsupported in a lip region of the person. a nasal bridge portion adapted to form a seal on the nasal bridge of the person; a side of nose region; at least one lateral stabilising portion adapted to provide a force in use on a side of the person's nose in the region of the nasal bridge of the person; a corner of mouth region; and a lower lip region; the cushion further comprising a retention feature adapted to interlock with the frame; a wall portion located between the retention feature of the cushion and the sealing portion, the wall portion having a first cross-sectional profile in the corner of mouth region, and a second cross-sectional profile in the side of nose region, wherein the sealing portion is supported along the sides of the person's nose, and characterized by that the sealing portion is substantially unsupported in a lip region of the person.
A polyolefin microporous film formed from a polyolefin composition comprising (i) a polyethylene, (ii) a first polypropylene having a viscosity average molecular weight of more than 50,000 and less than 300,000, and (iii) a second polypropylene having a viscosity average molecular weight of not less than 300,000; wherein the first polypropylene comprises a polypropylene homopolymer containing ethylene in an amount of not more than 1.0 % by mol, or a polypropylene copolymer containing ethylene in an amount of not more than 30 % by mol; and wherein the total amount of polyethylene in the polyolefin composition is not more than 97 % and not less than 70 % by mass; the total amount of polypropylene in the polyolefin composition is not less than 3 % and not more than 30 % by mass; and the mass ratio of the first polypropylene is 30 to 70 % by mass based on the total amount of the first and the second polypropylene. (i) a polyethylene, (ii) a first polypropylene having a viscosity average molecular weight of more than 50,000 and less than 300,000, and (iii) a second polypropylene having a viscosity average molecular weight of not less than 300,000;
A composition comprising Gc protein-derived macrophage activating factor (GcMAF) and less than 0.5 % glycosidase enzymes out of the total protein content of the composition, wherein the GcMAF is produced by a process comprising the steps of: (a) contacting Gc protein in vitro with the glycosidase enzyme β-galactosidase or with β-galactosidase in combination with at least one additional glycosidase enzyme, wherein each of the glycosidase enzymes being immobilized on a solid phase devoid of the enzyme substrate; and (b) removing the immobilized enzyme from the GcMAF composition.
A covering frame for a tarpaulin structure of a transport vehicle, in particular a railway wagon, comprising a plurality of carriages which are displaceable along a lateral guide, wherein at least one pivoting bow is pivotably connected to at least one or more of the carriages and, with the tarpaulin structure closed, assumes a greater angle to the vertical than with the tarpaulin structure opened, characterized in that at least one link is connected to at least one or more of the carriages and has a coupling to a link of a carriage which is adjacent with respect to a lateral guide, that a lifting bow is arranged in the region of the coupling, and that the coupling is axially displaceable with respect to the lifting bow at least in a vertical direction. a plurality of carriages which are displaceable along a lateral guide,
A process for selectively separating aromatics from a hydrocarbon stream containing aromatics, aliphatics and at least one alcohol, said process using a membrane consisting of a polyetheramine reacted with an epoxide.
A treatment system comprising: a plurality of electrodes; a memory device configured to store instructions for evaluating electrical signals; and a processor configured to execute the instructions to perform a method including: determining which of the plurality of electrodes are in contact with internal tissue; measuring electrical activity at each of the plurality of electrodes in contact with internal tissue; and determining at least one of the plurality of electrodes for treatment based on the measured electrical activity; characterized in that said system further comprises a display, and the method further includes: communicating to the display a virtual map including a representative marking with a first indicia for each of the plurality of electrodes; communicating to the display the representative marking with a second indicia for each of the plurality of electrodes determined to be in contact with internal tissue; and communicating to the display the representative marking for the at least one of the plurality of electrodes for treatment as a third indicia. a plurality of electrodes; a memory device configured to store instructions for evaluating electrical signals; and a processor configured to execute the instructions to perform a method including: determining which of the plurality of electrodes are in contact with internal tissue; measuring electrical activity at each of the plurality of electrodes in contact with internal tissue; and determining at least one of the plurality of electrodes for treatment based on the measured electrical activity; determining which of the plurality of electrodes are in contact with internal tissue; measuring electrical activity at each of the plurality of electrodes in contact with internal tissue; and determining at least one of the plurality of electrodes for treatment based on the measured electrical activity; characterized in that said system further comprises a display, and the method further includes: communicating to the display a virtual map including a representative marking with a first indicia for each of the plurality of electrodes; communicating to the display the representative marking with a second indicia for each of the plurality of electrodes determined to be in contact with internal tissue; and communicating to the display the representative marking for the at least one of the plurality of electrodes for treatment as a third indicia. communicating to the display a virtual map including a representative marking with a first indicia for each of the plurality of electrodes; communicating to the display the representative marking with a second indicia for each of the plurality of electrodes determined to be in contact with internal tissue; and communicating to the display the representative marking for the at least one of the plurality of electrodes for treatment as a third indicia.
A waste evacuation channel for evacuating fecal waste from a human colon, comprising: a lumen (609 and 610), sized for insertion of a distal end thereof to a distal end of said colon; said lumen having a lobed cross-section comprising at least a first and second lobe; a passage between said first and second lobes comprising at least one slot narrower than the widest extent of the cross-section of said first lobe; and said first lobe having a cross-sectional area at least 4 times larger than the cross-sectional area of said second lobe; characterized in that: passage of fluid between said first and second lobe is gated by a one-way valve member extending along said slot. a lumen (609 and 610), sized for insertion of a distal end thereof to a distal end of said colon; said lumen having a lobed cross-section comprising at least a first and second lobe; a passage between said first and second lobes comprising at least one slot narrower than the widest extent of the cross-section of said first lobe; and said first lobe having a cross-sectional area at least 4 times larger than the cross-sectional area of said second lobe;
An encoder configured to assign a code of less than N bits in length to a pattern of bits of a first value distributed within a block of N binary bits, when a number of bits, K, of the first value is limited to a fraction of N, and the encoder being characterized by: means for selecting a base value, Io, dependent on the number of bits, K, of the first value in the block of N binary bits which is configured to evaluate an Expression Io= N C 1 + N C 2 + N C 3...+ N C K-1; means for determining a displacement value representative of a particular distribution of the number of bits of the first value in the block of N binary bits, which is configured, if bit N is a binary first value bit, to recursively determine the displacement value I(N,K) as N-1 C K + I(N-1,K-1), where I(N-1,K-1) is the encoding of the pattern of K-1 number of remaining first value bits in N-1 bits, but if bit N is not a first value bit, to recursively determine the displacement value I(N,K) as I(N-1,K) where K is the encoding of the pattern of K number of first value bits in the remaining N-1 number of bits; and an adder configured to add the base value and the displacement value to obtain a sum. means for selecting a base value, Io, dependent on the number of bits, K, of the first value in the block of N binary bits which is configured to evaluate an Expression Io= N C 1 + N C 2 + N C 3...+ N C K-1; means for determining a displacement value representative of a particular distribution of the number of bits of the first value in the block of N binary bits, which is configured, if bit N is a binary first value bit, to recursively determine the displacement value I(N,K) as N-1 C K + I(N-1,K-1), where I(N-1,K-1) is the encoding of the pattern of K-1 number of remaining first value bits in N-1 bits, but if bit N is not a first value bit, to recursively determine the displacement value I(N,K) as I(N-1,K) where K is the encoding of the pattern of K number of first value bits in the remaining N-1 number of bits; and if bit N is a binary first value bit, to recursively determine the displacement value I(N,K) as N-1 C K + I(N-1,K-1), where I(N-1,K-1) is the encoding of the pattern of K-1 number of remaining first value bits in N-1 bits, but if bit N is not a first value bit, to recursively determine the displacement value I(N,K) as I(N-1,K) where K is the encoding of the pattern of K number of first value bits in the remaining N-1 number of bits; and an adder configured to add the base value and the displacement value to obtain a sum.
A torsional vibration damper having an axis of rotation for a drive train, having at least the following components: - a multi-flange damper having a plurality of flanges (5, 6, 7) for the shear torque-dependent and tensile torque-dependent damping of torsional vibrations; - a torque limiter unit arranged radially within the multi-flange damper and having inner plates and outer plates for limiting a maximum transmittable torque; - an outer hub arranged radially within the multi-flange damper and radially outside the torque limiter unit and which outer hub connects the multi-flange damper to the torque limiter unit in a torque-transmitting manner; and - an inner hub arranged radially inside the torque limiter unit for connection to a transmission input shaft, wherein the outer hub has an internal toothing, into which the outer plates of the torque limiter unit are suspended, characterized in that the outer hub has an external toothing in alternating shear torque-dependent and tensile torque-dependent engagement with the flanges (5, 6, 7) of the multi-flange damper. - a multi-flange damper having a plurality of flanges (5, 6, 7) for the shear torque-dependent and tensile torque-dependent damping of torsional vibrations; - a torque limiter unit arranged radially within the multi-flange damper and having inner plates and outer plates for limiting a maximum transmittable torque; - an outer hub arranged radially within the multi-flange damper and radially outside the torque limiter unit and which outer hub connects the multi-flange damper to the torque limiter unit in a torque-transmitting manner; and - an inner hub arranged radially inside the torque limiter unit for connection to a transmission input shaft, wherein the outer hub has an internal toothing, into which the outer plates of the torque limiter unit are suspended, characterized in that the outer hub has an external toothing in alternating shear torque-dependent and tensile torque-dependent engagement with the flanges (5, 6, 7) of the multi-flange damper.
A protein comprising one or more fragments of SEQ ID NO: 2884 of WO99/51280 (MKPKPHTVRTLIAAIFSLALSGCVSAVIGSAAVGAKSAVDRRTTG AQTDDNVMALRIETTARSYLRQNNQTKGYTPQISVVGYNRHLLLLGQVATEGEKQFVG QIARSEQAAEGVYNYITVASLPRTAGDIAGDTWNTSKVRATLLGISPATQARVKIVTYG NVTYVMGILTPEEQAQITQKVSTTVGVQKVITLYQNYVQR), wherein said fragment(s): (a) comprise at least one antigenic determinant; and (b) comprise a sequence selected from: and wherein said protein is not SEQ ID NOs: 2876, 2878, 2880, 2882, 2884 or 2886 of WO99/57280 (a) comprise at least one antigenic determinant; and (b) comprise a sequence selected from: and wherein said protein is not SEQ ID NOs: 2876, 2878, 2880, 2882, 2884 or 2886 of WO99/57280
An optical connector comprising a body, at least one socket to receive a fibre termination, and a clamp arranged to move to retain a fibre termination in position in the socket, wherein the socket includes at least one resilient wall and the clamp is adapted to press the resilient wall against a fibre termination in the socket, wherein the clamp is adapted to squeeze opposed sides of the socket, the connector being characterised in that the clamp comprises a slot through which the socket extends, one end of the slot being narrower than the other end, so that sliding movement of the clamp in a lateral direction across a socket axis squeezes the socket.
An environmental-friendly paintbrush, comprising a handle; a bristle-implanting brush head; and a metal plate, the bristle-implanting brush head having one end provided with a bristle material-laying trough and another end being connected with the handle; a plastic block placed inside the bristle material-laying trough; and bristle material filled in an interstitial space between the plastic block and the bristle-implanting brush head; wherein the plastic block is formed with a metal-laying trough and the metal plate is set inside the metal-laying trough, two ends of the bristle material-laying trough being formed with metal slots formed inside the bristle-implanting brush head, and two ends of the metal plate being slotted into the metal slots, wherein the plastic block has a V-shaped cross section, and the plastic block has one end located at a bottom end of the bristle-laying trough and another end provided with the metal-laying trough.