mhurhangee/ep-ind-claims huggingface dataset:
A process for preparing an asymmetric compound of Formula I: wherein: R 1 is a leaving group, a protected amino group, NO 2, or OH or its protected form; R 2 is hydrogen; R 3 is (C=O)OR 5, CH 2 R 6, or a protected aldehyde; or, R 2 and R 3 are combined to form a nitrogen containing heterocyclyl selected from R4 is hydrogen or an amino protecting group; R 5 is C 1-6 alkyl, C 3-10 cycloalkyl, C 4-10 heterocyclyl, aryl, or heteroaryl; and, R 6 is a leaving group or OH or its protected form; comprising a biocatalytic transamination of a compound of Formula II: wherein: R 1 is as defined above; R 2' is an aldehyde or an aldehyde equivalent; and, R 3' is R 3; or R 2' and R 3' are combined to form in the presence of a transaminase polypeptide, a coenzyme, and an amino donor. R 1 is a leaving group, a protected amino group, NO 2, or OH or its protected form; R 2 is hydrogen; R 3 is (C=O)OR 5, CH 2 R 6, or a protected aldehyde; or, R 2 and R 3 are combined to form a nitrogen containing heterocyclyl selected from R4 is hydrogen or an amino protecting group; R 5 is C 1-6 alkyl, C 3-10 cycloalkyl, C 4-10 heterocyclyl, aryl, or heteroaryl; and, R 6 is a leaving group or OH or its protected form; R 1 is as defined above; R 2' is an aldehyde or an aldehyde equivalent; and, R 3' is R 3; or R 2' and R 3' are combined to form
A method of processing spectra of radiation scattered by a material in order to obtain a spectrum of primary radiation scattered by said material, in which the material is exposed to an incident irradiation beam emitted by a radiation source and at least one spectrum of radiation scattered by the material is measured, characterized in that it comprises: - measuring a spectrum of primary radiation scattered by the material by means of a detector, referred to as main detector, arranged so that an observation field of the main detector intersects the incident irradiation beam inside the material, - measuring at least one other spectrum (152, 154, 156) of radiation scattered by the material, referred to as secondary spectrum, by means of at least one detector (122, 124, 126) referred to as secondary detector, - constituting a matrix, referred to as measurements matrix, from previously measured spectra, - then performing decomposition of said measurements matrix into two non-negative matrices, which are a matrix referred to as weights matrix, of which each term a ij represents the proportion of primary or multiple scattered radiation j measured by the detector i and a matrix, referred to as spectra matrix, the latter comprising an estimated multiple scattered radiation spectrum and an estimated primary scattered radiation spectrum, this decomposition being preceded by a step of initializing the weights matrix and the spectra matrix. - measuring a spectrum of primary radiation scattered by the material by means of a detector, referred to as main detector, arranged so that an observation field of the main detector intersects the incident irradiation beam inside the material, - measuring at least one other spectrum (152, 154, 156) of radiation scattered by the material, referred to as secondary spectrum, by means of at least one detector (122, 124, 126) referred to as secondary detector, - constituting a matrix, referred to as measurements matrix, from previously measured spectra, - then performing decomposition of said measurements matrix into two non-negative matrices, which are a matrix referred to as weights matrix, of which each term a ij represents the proportion of primary or multiple scattered radiation j measured by the detector i and a matrix, referred to as spectra matrix, the latter comprising an estimated multiple scattered radiation spectrum and an estimated primary scattered radiation spectrum, this decomposition being preceded by a step of initializing the weights matrix and the spectra matrix.
Method for using a resource of a hardware platform with at least two virtual machines, wherein a virtualization controller for administering the virtual machines runs on the hardware platform, wherein a first machine of the virtual machines with a first operating system (RTOS) runs separately on at least a first processor core (core 1) or a first processor, wherein a number of further virtual machines runs on at least one further processor core (core 0) or processor, wherein one of the further virtual machines is embodied as a service machine, wherein this service machine has a first driver for accessing the resource, wherein the first operating system (RTOS) has a para-virtualized second driver for accessing the resource, and wherein requests by the para-virtualized second driver to access the resource via the virtualization controller are directed to the first driver, wherein the first driver converts the requests into access operations to the resource, and wherein in the course of the requests by the para-virtualized second driver an inter-processor interrupt is transmitted from the first virtual machine to the further processor core (core 0) or processor with the service machine, wherein the service machine jumps into a processing routine of the first driver.
Solder pot, in particular a selective solder pot for a soldering system for selective wave soldering, comprising a solder pump (10, 100) for conveying an electrically conductive fluid, in particular a liquid solder, which pump is equipped with a conveyor channel, which extends along a circular path at least in portions and has an inlet and an outlet, and with a device for generating a moving magnetic field, the device comprising at least one permanent magnet and being designed such that the permanent magnet is moved along the conveyor channel during operation, and during operation rotates about an axis of rotation which is arranged concentrically to the circular path, characterized in that the conveyor channel, on the side thereof which faces away from the permanent magnet, is delimited by a ferromagnetic material, and in that the conveyor channel, on the side thereof which faces the permanent magnet, is delimited by a non-ferromagnetic material.
Device for watering purposes and comprising a water-collecting container that extends along the intended desired area to be watered and is arranged to be received in the ground, wherein internally in the container, there is a transverse wall, which extends from the base portion of the container up to at least half the effective height of the container, wherein along the outside of the container, a liquid-sucking wick extends that is connected to internal liquid-receiving compartments (12, 13) of the container at a mutual distance from each other, as seen along the length extension of the container, and wherein the wick is arranged to extend through openings on the upperside of the container to base portions of the container characterized in that, the wall is a double partition wall, the liquid-sucking wick is connected to the internal liquid-receiving compartments (12, 13) at the area of the respective partition wall on each side of the same and the active suction capacity of the wick between container compartments (12, 13) provided being interrupted in order to prevent water transportation by means of the wick between the container compartments (12, 13).
An isolation system for capturing and processing cells, the isolation system comprising a container, wherein said container is in form of a bag or tube configured for the isolation and collection of cells of one or more desired cell types from a fluid sample, and comprises: an inner surface comprising a fluoropolymer having a total organic carbon in water of less than 100 μg/mL measured according to US Pharmacopeia 643 and with equipment that utilizes a high temperature wet oxidation reaction of UV-promoted chemical oxidation as described in the Ultra-Clean Technology Handbook: Volume 1: Ultra-Pure Water, Ohmi, Tadahiro; CRC Press, 1993, pp. 497-517, by contacting water with the fluoropolymer for 24 hours at 70 °C at a ratio of 3 cm 2 of fluoropolymer surface area to 1 mL of water, and a plurality of functional groups covalently attached to the fluoropolymer, each functional group being a carboxy group, hydroxyl group, aldehyde group, carbonyl group, amine group, imine group, amide group, ester group, anhydride group, thiol group, disulfides, phenols, guanidines, thioethers, indoles, imidazoles, or diazonium surface group, wherein the functional groups are directly or indirectly attached to a cell-capturing moiety, the cell-capturing moiety being configured to selectively capture cells of the one or more cell types. an inner surface comprising a fluoropolymer having a total organic carbon in water of less than 100 μg/mL measured according to US Pharmacopeia 643 and with equipment that utilizes a high temperature wet oxidation reaction of UV-promoted chemical oxidation as described in the Ultra-Clean Technology Handbook: Volume 1: Ultra-Pure Water, Ohmi, Tadahiro; CRC Press, 1993, pp. 497-517, by contacting water with the fluoropolymer for 24 hours at 70 °C at a ratio of 3 cm 2 of fluoropolymer surface area to 1 mL of water, and Volume 1: Ultra-Pure Water, Ohmi, Tadahiro; CRC Press, 1993, pp. 497-517, by contacting water with the fluoropolymer for 24 hours at 70 °C at a ratio of 3 cm 2 of fluoropolymer surface area to 1 mL of water, and a plurality of functional groups covalently attached to the fluoropolymer, each functional group being a carboxy group, hydroxyl group, aldehyde group, carbonyl group, amine group, imine group, amide group, ester group, anhydride group, thiol group, disulfides, phenols, guanidines, thioethers, indoles, imidazoles, or diazonium surface group, wherein the functional groups are directly or indirectly attached to a cell-capturing moiety, the cell-capturing moiety being configured to selectively capture cells of the one or more cell types.
A system, comprising: one or more computing devices that implement a graph database to: store a plurality of data elements in the graph database, wherein individual data elements of the plurality of data elements comprise a triple stored in a triple store table, wherein individual triples comprise at least a subject identifier, column name, and a value for the column name, wherein the column names are globally scoped in the graph database, and wherein the column names are associated with respective data types for the values; create indices corresponding to the column names, wherein an individual one of the indices comprises one or more of the values associated with the corresponding column name; and perform a query on the graph database, wherein the query returns one or more of the values, and wherein the query is performed using one or more of the indices corresponding to one of more of the column names associated with the query. store a plurality of data elements in the graph database, wherein individual data elements of the plurality of data elements comprise a triple stored in a triple store table, wherein individual triples comprise at least a subject identifier, column name, and a value for the column name, wherein the column names are globally scoped in the graph database, and wherein the column names are associated with respective data types for the values; create indices corresponding to the column names, wherein an individual one of the indices comprises one or more of the values associated with the corresponding column name; and perform a query on the graph database, wherein the query returns one or more of the values, and wherein the query is performed using one or more of the indices corresponding to one of more of the column names associated with the query.
A vehicular pedestrian protection airbag device (28, 70) comprising: an inflator that is installed at a lower side of a rear end section of a hood capable of being raised toward a vehicle upper side at the rear end section, and that ejects gas on actuation; a pedestrian protection airbag that is stowed in a folded state at the lower side of the rear end section of the hood, and that inflates and deploys from between the rear end section of the hood and a windshield glass toward a vehicle upper face side and a vehicle rear side by being supplied with gas from the inflator; and an inflator attachment bracket including a first fixing portion fixed to a lower face side of the rear end section of the hood, a second fixing portion to which the inflator is fixed, and a deformation portion (52, 88, 128) that is provided between the first fixing portion and the second fixing portion and that plastically deforms by stretching or compressing so as to permit movement of the inflator toward an opposite direction from an inflation and deployment direction of the pedestrian protection airbag. an inflator that is installed at a lower side of a rear end section of a hood capable of being raised toward a vehicle upper side at the rear end section, and that ejects gas on actuation; a pedestrian protection airbag that is stowed in a folded state at the lower side of the rear end section of the hood, and that inflates and deploys from between the rear end section of the hood and a windshield glass toward a vehicle upper face side and a vehicle rear side by being supplied with gas from the inflator; and an inflator attachment bracket including a first fixing portion fixed to a lower face side of the rear end section of the hood, a second fixing portion to which the inflator is fixed, and a deformation portion (52, 88, 128) that is provided between the first fixing portion and the second fixing portion and that plastically deforms by stretching or compressing so as to permit movement of the inflator toward an opposite direction from an inflation and deployment direction of the pedestrian protection airbag.
A storage system, wherein the storage system comprises control logic, and a write control interface and a read control interface that are coupled to a memory, a storage area in the memory comprises a first page and a second page, and the control logic is configured to: set the first page to write-only and the second page to read-only; in specified slots, write data to the first page through the write control interface, and read data from the second page through the read control interface; set the first page to read-only and the second page to write-only when a quantity of the specified slots reaches a preset quantity of slots; and in specified slots of a next round, read data from the first page through the read control interface, and write data to the second page through the write control interface; wherein for each slot in the specified slots, data that is written to the first page and corresponding to the slot comprises N written data units; before writing data to the first page, the control logic is further configured to determine a first column address and a first row address of each of the N written data units on the first page, wherein the first row addresses of the N written data units are different from each other; and correspondingly, the control logic is specifically configured to write the N written data units to the first page based on the first column address and the first row address of each of the N written data units. set the first page to write-only and the second page to read-only; in specified slots, write data to the first page through the write control interface, and read data from the second page through the read control interface; set the first page to read-only and the second page to write-only when a quantity of the specified slots reaches a preset quantity of slots; and in specified slots of a next round, read data from the first page through the read control interface, and write data to the second page through the write control interface; wherein for each slot in the specified slots, data that is written to the first page and corresponding to the slot comprises N written data units; before writing data to the first page, the control logic is further configured to determine a first column address and a first row address of each of the N written data units on the first page, wherein the first row addresses of the N written data units are different from each other; and correspondingly, the control logic is specifically configured to write the N written data units to the first page based on the first column address and the first row address of each of the N written data units.
A dispenser, which is filled with a gel comprising a C 1 to C 10 carboxylic acid and a thickener, comprising a polyester membrane, wherein the polyester is a semiaromatic copolyester.
A method of preparing an ester-based composition, the method comprising reacting a) a dibenzoic acid represented by Chemical Formula 1 below; b) one or more selected from the group consisting of a carboxylic acid represented by Chemical Formula 2 below and a carboxylic acid ester-based material including one or more compounds represented by Chemical Formula 5 below; and c) an alcohol including one or more compounds represented by Chemical Formula 3 below, wherein a product of the reaction includes a benzoic acid ester-based material including one or more compounds represented by Chemical Formula 4 below and a carboxylic acid ester-based material including one or more compounds represented by Chemical Formula 5 below: wherein n is 2, wherein R 1 is a C1 or C2 alkyl group, [Chemical Formula 3] R 2 -OH wherein R 2 is a C1 to C12 linear alkyl group or a C3 to C12 branched alkyl group, wherein R 2a and R 2b are the same or different from each other, and each independently are a linear alkyl group or a C3 to C12 branched alkyl group, wherein R 1a is a C1 or C2 alkyl group, and R 2c is a C1 to C12 linear alkyl group or a C3 to C12 branched alkyl group, wherein the carboxylic acid ester-based material is included at 11 parts by weight or less with respect to 100 parts by weight of the dibenzoic acid represented by Chemical Formula 1.
A piercing device for delivering a predetermined quantity of a flowable liquid or powder contained in a crushable blister into a spray, plume, stream or droplets, said device comprising: a base comprising a top; a substantially hollow, elongated member extending from the base and comprising a body region and terminating in a lancet piercing tip region; an internal delivery channel formed by the hollow interior of the elongated member extending from the base and terminating in a plurality of discharge ports arranged around the base of the piercing tip; one or more inlet ports in the base in fluid communication with the interior of the crushable blister; and one or more conduits providing fluid communication between the one or more inlet ports and the internal delivery channel; wherein the internal delivery channel comprises: a central cavity extending from, and in fluid communication with the inlet channels, and a plurality of outlet channels radially disposed around the central cavity and open to the central cavity along at least a portion of the innermost side of each outlet channel and terminating in a dispensing port, wherein the central cavity is defined by angular walls disposed between the outlet channels and an angular top surface proximate the tip. a base comprising a top; a substantially hollow, elongated member extending from the base and comprising a body region and terminating in a lancet piercing tip region; an internal delivery channel formed by the hollow interior of the elongated member extending from the base and terminating in a plurality of discharge ports arranged around the base of the piercing tip; one or more inlet ports in the base in fluid communication with the interior of the crushable blister; and one or more conduits providing fluid communication between the one or more inlet ports and the internal delivery channel; wherein the internal delivery channel comprises: a central cavity extending from, and in fluid communication with the inlet channels, and a plurality of outlet channels radially disposed around the central cavity and open to the central cavity along at least a portion of the innermost side of each outlet channel and terminating in a dispensing port, a central cavity extending from, and in fluid communication with the inlet channels, and a plurality of outlet channels radially disposed around the central cavity and open to the central cavity along at least a portion of the innermost side of each outlet channel and terminating in a dispensing port, wherein the central cavity is defined by angular walls disposed between the outlet channels and an angular top surface proximate the tip.
Commutation method for resonant oscillation of an output voltage ( U Out) provided at a voltage output of an energy converter from a starting potential ( U ZK; GND) to a target potential ( GND; U ZK), wherein the energy converter can connect the output voltage ( U Out) with a first controllable electronic main switch with an antiparallel first freewheeling diode to a supply voltage ( U ZK) connected to a supply voltage connection and with a second controllable electronic main switch with an antiparallel second freewheeling diode to a reference potential connected to a reference potential connection, and wherein from the voltage output a first oscillating capacitor goes to the supply voltage connection and/or a second oscillating capacitor goes to the reference potential connection and an oscillating inductance (L res) goes to a control input, wherein while oscillating the main switches (T1, T2) are opened and a control voltage ( U BASE,RES) is connected to the control input, which control voltage lies closer to the target potential ( GND; U ZK) than to the starting potential ( U ZK; GND) by a voltage amount ( U Boost) greater than 0 V, characterised in that the control voltage ( U BASE,RES) is set by at least one transformer with at least two windings (L1, L2; L1-H, L1-L, L2-H, L2-L), wherein the at least one first winding (L1; L1-H, L1-L) is connected on one side with the control input.
An isolated T cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/ or fragment thereof, wherein the HBV epitope is HLA-A2 restricted, and is: HBV epitope is HBc18-27 epitope comprising SEQ ID NO:25 and/or SEQ ID NO:26; and/or HBs370-79 epitope comprising any one of sequences selected from the group consisting of SEQ ID NO: 56 to 58; and wherein the fragment comprises an active site which enable the HBV-epitope-reactive exogenous T cell receptor to recognise the HBc18-27 and/or the HBs370-79 epitope. HBV epitope is HBc18-27 epitope comprising SEQ ID NO:25 and/or SEQ ID NO:26; and/or HBs370-79 epitope comprising any one of sequences selected from the group consisting of SEQ ID NO: 56 to 58;
A process for treating a synthesis gas stream comprising steam reforming firstly in a primary reformer and subsequently in a secondary reformer, wherein the crude synthesis gas exiting the secondary reformer is cooled in a steam generator and is then further cooled in a steam superheater, wherein the crude synthesis gas stream after exiting the secondary reformer is split into at least two gas substreams (113, 123), of which only a first gas substream is fed to the steam generator, while a second gas substream is supplied to the steam superheater bypassing the steam generator, wherein the process further comprises a CO conversion of the synthesis gas stream in a CO conversion reactor, characterized in that only the first gas substream, after flowing through the steam generator, is subjected to a CO conversion reaction in a first CO conversion reactor, before this first gas substream is supplied to the steam superheater.