A vehicle door structure comprising: a door outer panel that is made of metal and structures a design surface of a vehicle door; an annular reinforcement that is made of metal, and that is provided at a door inner side of the door outer panel, and that is formed in an annular shape to run along an outer peripheral portion of the door outer panel, and that is joined to the outer peripheral portion, and to which one or a plurality of reinforcing member (36, 40, 42) that extend in a door longitudinal direction are joined; a door inner panel that is made of a resin, and is provided at a door inner side of the annular reinforcement, and is fastened and fixed to the annular reinforcement; and a beltline outer reinforcement that serves as the reinforcing member and that is provided at a door inner side of an upper end portion of the door outer panel, the vehicle door structure being characterized in that the resin is a fiber-reinforced resin, and in that it further comprises: a lock reinforcement that is made of metal, that is provided at a door outer side of a door rear portion of the door inner panel, and that is configured to receive a door lock device; and a handle reinforcement that is made integral with the beltline outer reinforcement, and that is configured to receive an outside handle of the vehicle door, wherein the handle reinforcement, the annular reinforcement, the lock reinforcement and the door inner panel are fastened together by a fastening member (B2, N2). a door outer panel that is made of metal and structures a design surface of a vehicle door; an annular reinforcement that is made of metal, and that is provided at a door inner side of the door outer panel, and that is formed in an annular shape to run along an outer peripheral portion of the door outer panel, and that is joined to the outer peripheral portion, and to which one or a plurality of reinforcing member (36, 40, 42) that extend in a door longitudinal direction are joined; a door inner panel that is made of a resin, and is provided at a door inner side of the annular reinforcement, and is fastened and fixed to the annular reinforcement; and a beltline outer reinforcement that serves as the reinforcing member and that is provided at a door inner side of an upper end portion of the door outer panel, the vehicle door structure being characterized in that the resin is a fiber-reinforced resin, and in that it further comprises: a lock reinforcement that is made of metal, that is provided at a door outer side of a door rear portion of the door inner panel, and that is configured to receive a door lock device; and a handle reinforcement that is made integral with the beltline outer reinforcement, and that is configured to receive an outside handle of the vehicle door, a lock reinforcement that is made of metal, that is provided at a door outer side of a door rear portion of the door inner panel, and that is configured to receive a door lock device; and a handle reinforcement that is made integral with the beltline outer reinforcement, and that is configured to receive an outside handle of the vehicle door, wherein the handle reinforcement, the annular reinforcement, the lock reinforcement and the door inner panel are fastened together by a fastening member (B2, N2).