mhurhangee/ep-ind-claims huggingface dataset:
An expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide with an insert for use in the treatment or prophylaxis of cancer, wherein the insert is an amino acid sequence of up to 80 amino acids in length comprising a specific epitope of VEGF or angiopoietin-2, wherein the amino acid sequence comprising the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide, wherein the specific epitope of VEGF consists of the amino acid sequence shown in SEQ ID NO: 32 or 33, or a partial sequence thereof having 13 or more amino acids containing the amino acid sequence shown in SEQ ID NO: 31, and wherein the specific epitope of angiopoietin-2 consists of the amino acid sequence shown in SEQ ID NO: 3.
An additive manufacturing apparatus for additive manufacturing of three dimensional objects by selectively solidifying a powder material layer by layer in a process chamber, the apparatus comprising: a powder distributor (230, 330) movable across a build area of a build tank and configured for applying a layer of powder material thereon; a solidification device configured for selectively solidifying the applied powder layer at positions corresponding to a cross section of the object to be manufactured; a control unit adapted to manipulate the powder distributor (230, 330) and the solidification device to repeat the steps of applying and selectively solidifying until the object is completed; and at least one support structure (240, 340) configured for supporting said powder distributor (230, 330) and connected or connectable to a cooling/heating media supply positioned outside said process chamber, said support structure (240, 340) being configured for transporting said cooling/heating media to and from said powder distributor (230, 330); wherein inside the support structure (240, 340) it is provided one or a plurality of channels for allowing transport of cooling/heating media from outside the process chamber via the support structure (240, 340) to the powder distributor (230, 330), wherein the powder distributor (230, 330) is in turn provided with one or a plurality of internal channels for allowing transport of the cooling/heating media; wherein said cooling/heating media is at least one of a gas or liquid. a powder distributor (230, 330) movable across a build area of a build tank and configured for applying a layer of powder material thereon; a solidification device configured for selectively solidifying the applied powder layer at positions corresponding to a cross section of the object to be manufactured; a control unit adapted to manipulate the powder distributor (230, 330) and the solidification device to repeat the steps of applying and selectively solidifying until the object is completed; and at least one support structure (240, 340) configured for supporting said powder distributor (230, 330) and connected or connectable to a cooling/heating media supply positioned outside said process chamber, said support structure (240, 340) being configured for transporting said cooling/heating media to and from said powder distributor (230, 330); wherein inside the support structure (240, 340) it is provided one or a plurality of channels for allowing transport of cooling/heating media from outside the process chamber via the support structure (240, 340) to the powder distributor (230, 330), wherein the powder distributor (230, 330) is in turn provided with one or a plurality of internal channels for allowing transport of the cooling/heating media; wherein said cooling/heating media is at least one of a gas or liquid.
A communication circuit (300, 400, 500) for reducing spur energy of a modulated signal (LO OUT), the communication circuit (300, 400, 500) comprising a digital-to-time converter (330, 430, 561) characterized in that the digital-to-time converter (330, 430, 561) is configured to receive reference information (LO IN), to receive modulation information (f, ψ), to receive first dither information (δ) and to provide the modulated signal (LO OUT) using the reference information (LO IN), the modulation information (f, ψ) and the first dither information (δ); and a processing path (441, 451) configured to receive second dither information (e -jδ) and to cancel the first dither information (δ) using the second dither information (e -jδ), wherein the first dither information (δ) is configured to disrupt processing periodicity of the communication circuit (300, 400, 500) to reduce spur energy.
Pneumatic vehicle tyre with two or more bracing plies, intersecting one another at an angle and having reinforcing elements, and with a bracing bandage, made up of one or more plies and having reinforcing elements, wherein the reinforcing elements of the bracing plies are made exclusively of steel, and within each bracing ply are arranged substantially parallel to and at a distance from one another and are embedded in rubber material, wherein the reinforcing elements of the bracing plies form an angle of 18° to 45° with the circumferential direction of the tyre, and wherein the reinforcing elements of the bracing bandage are of a non-metallic material, are arranged within the reinforcing element ply substantially parallel to and at a distance from one another approximately in the circumferential direction of the tyre and have heat shrinkage properties, characterized in that, under a predetermined extension of 1% in the direction of the longitudinal extent of the reinforcing elements, at least one bracing ply has a tension of < 19 000 N per dm of width, and in that, under a predetermined extension of 1% in the direction of the longitudinal extent of the reinforcing elements, a bracing ply has a lower tension per dm of width than the other(s), and in that the reinforcing elements of this one bracing ply form a greater angle with the circumferential direction of the tyre than those of the other bracing ply (plies).
A method for assembling an electrical connector assembly to a case, the case forms a fully or substantially enclosed case, having an inside surface defining an inside of said case, an outside surface defining an outside of said case, and an aperture therethrough providing communication from said inside surface to said outside surface; said electrical connector assembly having an outer connector having a body, extending along an axis, with a passage therethrough, an electromagnetic shield, and an inner connector with a terminal therein with a conductor extending from said inner connector in electrical communication with said terminal; said method comprising: positioning said outer connector on said outside of said case to align said passage of said outer connector with said aperture of said case; positioning said inner connector into the passage of the outer connector on said inside of said case; and inserting said inner connector into said passage of said outer connector through said aperture from said inside of said case; and positioning said electromagnetic shield within said passage of said outer connector; and surrounding said inner connector with said electromagnetic shield; and fixing said outer connector to said case, wherein said outer connector includes a flange extending outward therefrom, a plurality of outer connector attachment holes extend through the flange parallel to axis, and said step of fixing said outer connector to said case uses said flange, whereby each outer connector attachment hole receives a fastener which threadably engages a corresponding threaded hole in the case in order to attach outer connector to the case. positioning said outer connector on said outside of said case to align said passage of said outer connector with said aperture of said case; positioning said inner connector into the passage of the outer connector on said inside of said case; and inserting said inner connector into said passage of said outer connector through said aperture from said inside of said case; and positioning said electromagnetic shield within said passage of said outer connector; and surrounding said inner connector with said electromagnetic shield; and fixing said outer connector to said case, wherein said outer connector includes a flange extending outward therefrom, a plurality of outer connector attachment holes extend through the flange parallel to axis, and said step of fixing said outer connector to said case uses said flange, whereby each outer connector attachment hole receives a fastener which threadably engages a corresponding threaded hole in the case in order to attach outer connector to the case.
An actuator system for generating positioning movements by means of shape memory elements, comprising an actuation member disposed in a housing and coupled to shape memory actuators to perform positioning movements, and a modular actuator system that comprises at least two individual actuators (6, 7) and generates a positioning movement of an actuation member, with the individual actuators (6, 7, 8, 9) having at least one shape memory element and at least one activation element (12, 13), and with the individual actuators (6, 7, 8, 9) being exchangeably arranged in the common housing and realised as standardised actuators, and with the actuation member being coupled to at least two individual actuators (6, 7) consisting of shape memory elements, such that when a transformation temperature is exceeded, the first individual actuator generates a translational actuating movement of the actuation member and, if required, the second individual actuator is activated and performs a further actuating movement, thus making it possible for the actuation member to move on to another actuation position or to fine adjust its first actuation position, characterised in that - the actuation member is realised as a carriage performing a positioning movement, with the carriage being guided by two guide columns (3, 4) arranged within the housing in such a manner that it may perform a translational movement in two directions, - the at least one activation element (12, 13) is longitudinally guided within a housing of the individual actuator (6, 7, 8, 9), and - the individual actuators (6, 7, 8, 9) have at least a two-step motion characteristics. - the actuation member is realised as a carriage performing a positioning movement, with the carriage being guided by two guide columns (3, 4) arranged within the housing in such a manner that it may perform a translational movement in two directions, - the at least one activation element (12, 13) is longitudinally guided within a housing of the individual actuator (6, 7, 8, 9), and - the individual actuators (6, 7, 8, 9) have at least a two-step motion characteristics.
A mold segment comprising a tread molding element for manufacturing a tire, wherein the tread molding element comprises a shell and an infill, the shell having i) a first wall with a negative tread pattern extending from its external surface for molding the tread, ii) a second wall opposed to the first wall, and iii) lateral walls; wherein the infill is a fluid-permeable structure defining a fluid-permeable infill; and wherein at least one selected from a lateral wall and the second wall comprises at least one fluid passage passing through the lateral wall or the second wall and is fluidly connected to or is open to the fluid permeable infill, characterized in that the negative tread pattern comprises one or more of sipes, ribs and blades which are integral with the first wall, wherein at least one rib or blade is hollow and open to the internal surface of the first wall, and in that the mold segment (3, 23, 45) comprises two transverse edges with transverse edge walls wherein one or both of the transverse edge walls have one or more openings to form a fluid passage intended for a fluid connection of the infill of said mold segment (3, 23, 45) with the infill of another mold segment (3, 23, 45) placed adjacently in a tire mold assembly being in a closed configuration.
A method for configuring dual connectivity operation of a first cellular network, in which a User Equipment, UE, is configured to operate with the first cellular network as a first subscriber and to operate simultaneously with a second cellular network as a second, different subscriber, the UE simultaneously operating with the first cellular network using both a Master Cell Group, MCG, and a Secondary Cell Group, SCG, the method comprising: controlling activation and/or deactivation of the SCG, in response to activity of the UE with the second cellular network, by communicating a Medium Access Control, MAC, Control Element, CE.
An electrode meandering correction device, which is a meandering correction device at the time of transferring an electrode to be wound around a winding core to form a jelly roll electrode assembly, the electrode meandering correction device comprising: an input inclination adjustment mechanism of an input clamp configured to input the electrode to the winding core; an edge position control unit provided with a determination edge position sensor disposed before the winding core to measure an edge position of the electrode as a determination EPS edge position value, and an EPC roller configured to adjust the edge position of the electrode to match a determination EPS edge reference value; and a controller configured to control the EPC unit and the input inclination adjustment mechanism, wherein the controller feedback-controls the edge position of the electrode so that the determination EPS edge position value matches the determination EPS edge reference value, acquires determination EPS edge position value data when the determination EPS edge position value changes over time to converge to the determination EPS edge reference value by the feedback control, and selects data values changed by influence of the input inclination of the input clamp from among the determination EPS edge position value data and feedback-controls the input inclination adjustment mechanism to correct the input inclination by comparison of these data values and the determination EPS edge reference value. an input inclination adjustment mechanism of an input clamp configured to input the electrode to the winding core; an edge position control unit provided with a determination edge position sensor disposed before the winding core to measure an edge position of the electrode as a determination EPS edge position value, and an EPC roller configured to adjust the edge position of the electrode to match a determination EPS edge reference value; and a controller configured to control the EPC unit and the input inclination adjustment mechanism, wherein the controller feedback-controls the edge position of the electrode so that the determination EPS edge position value matches the determination EPS edge reference value, acquires determination EPS edge position value data when the determination EPS edge position value changes over time to converge to the determination EPS edge reference value by the feedback control, and selects data values changed by influence of the input inclination of the input clamp from among the determination EPS edge position value data and feedback-controls the input inclination adjustment mechanism to correct the input inclination by comparison of these data values and the determination EPS edge reference value.
A computer-implemented method for improving an efficiency of a cargo shipping system, the method comprising: receiving, by a server, a cargo transportation unit, CTU, status notification from a cargo tracking device installed on a CTU, wherein the CTU status notification indicates a load status of the CTU, and wherein the CTU status notification is received periodically, and wherein the cargo tracking device determines a current speed of the CTU based on a change of location of the CTU and the cargo tracking device changes a periodicity of the CTU status notification based on the current speed of the CTU; in response to receipt of the CTU status notification, determining, by the server, that the CTU is ready for shipment; receiving, by the server, availability information associated with each of a plurality of drivers; selecting, by the server and based on the CTU status notification and the availability information, a driver for the CTU from the plurality of drivers; and sending a delivery request to the selected driver. receiving, by a server, a cargo transportation unit, CTU, status notification from a cargo tracking device installed on a CTU, wherein the CTU status notification indicates a load status of the CTU, and wherein the CTU status notification is received periodically, and wherein the cargo tracking device determines a current speed of the CTU based on a change of location of the CTU and the cargo tracking device changes a periodicity of the CTU status notification based on the current speed of the CTU; in response to receipt of the CTU status notification, determining, by the server, that the CTU is ready for shipment; receiving, by the server, availability information associated with each of a plurality of drivers; selecting, by the server and based on the CTU status notification and the availability information, a driver for the CTU from the plurality of drivers; and sending a delivery request to the selected driver.
A structure for mounting an anti-fog sheet to a shield, the structure comprising a plurality of seat parts that are formed on a peripheral edge part of an anti-fog sheet covering an inner face of a shield, a plurality of support holes that are provided in the shield at positions corresponding to the seat parts, and a plurality of retaining members that retain the anti-fog sheet by being seated on the seat parts while being supported by the support holes, wherein the retaining member is formed as a single component comprising a main shaft that has at one end a head portion abutting against an outer face of the shield and is rotatably fitted into the support hole, an eccentric shaft that is connectedly provided eccentrically and integrally with the other end of the main shaft, can be seated on the seat part, and has a smaller diameter than the main shaft has, and an expanded end part that is connectedly provided integrally with an outer end of the eccentric shaft, defines an annular groove around the eccentric shaft in cooperation with the main shaft, and can pass through the support hole, characterized in that the retaining member is formed from a synthetic resin; the main shaft is provided with a slit that extends through substantially the entire length thereof at a position away from a central axis thereof and opens in the annular groove, and the slit divides the main shaft into a main shaft main portion that is connected to the eccentric shaft and an elastic piece that has a free end and forms an elastic deformation part, a load acting on the retaining member from the shield and the anti-fog sheet being absorbed by elastic deformation of the elastic deformation part (17, 19).
Support device which can be fastened to a trailer drawbar, having an outer tube which can be fastened to the trailer drawbar, an inner tube which is held in the outer tube in a telescopically height-adjustable manner by means of a crank handle, wherein wheel lugs, which project outwards relative to the outer tube and between which a support wheel is mounted, are fastened to an end of the inner tube remote from the crank handle, wherein a first inlet element is provided on the support device, with which a second inlet element can be brought into operative connection in such a way that the support wheel is pivoted into a predetermined angular position when the inner tube is retracted into the outer tube before reaching the retracted end position of the inner tube, characterized in that the first inlet element is designed as an inlet ring or inlet partial ring with a groove which is recessed in its outer circumference and tapers towards the inner circumference.
Method for influencing a lighting scene in front of a vehicle, wherein the method comprises the following steps: reading-in an item of information about a position of at least one identified object and about a class of the identified object; assigning a lighting region, which is related to the position of the object, a lighting intensity, which is related to the class of the object, for the lighting region; and adapting the lighting scene taking into account the lighting region and the associated lighting intensity, characterized in that a lighting period, which is related to the class of the object, is assigned in the assigning step, and the lighting scene is further adapted taking into account the lighting period in the adapting step, and wherein, in response to a deer being identified in front of the vehicle, in particular at the roadside, a point at which the deer has been identified is illuminated for longer than the deer is at the point, and/or, in response to a traffic sign being identified, a point at which a traffic sign has been identified is illuminated for longer, even though the traffic sign is briefly hidden and therefore not even visible. reading-in an item of information about a position of at least one identified object and about a class of the identified object; assigning a lighting region, which is related to the position of the object, a lighting intensity, which is related to the class of the object, for the lighting region; and adapting the lighting scene taking into account the lighting region and the associated lighting intensity, characterized in that a lighting period, which is related to the class of the object, is assigned in the assigning step, and the lighting scene is further adapted taking into account the lighting period in the adapting step, and wherein, in response to a deer being identified in front of the vehicle, in particular at the roadside, a point at which the deer has been identified is illuminated for longer than the deer is at the point, and/or, in response to a traffic sign being identified, a point at which a traffic sign has been identified is illuminated for longer, even though the traffic sign is briefly hidden and therefore not even visible.
An electrode guide for inserting a cochlear implant electrode array into a cochlea scala, the guide comprising: an elongated guide member (406, 500, 600, 700, 800, 900, 1000, 1100) configured to define an insertion passage for an electrode array, said insertion passage extending through an outer mastoid cortex surface to a cochleostomy opening into a cochlea scala.