A system for digital imaging in a light deficient environment comprising: an emitter that is configured to emit a plurality of pulses of differing wavelengths of electromagnetic radiation for providing illumination in an environment at a plurality of different exposures; an image sensor that is configured to sense the pulses of electromagnetic radiation reflected from the environment and to create image data therefrom; wherein said image sensor comprises a pixel array (2902, 2904) that is configured to sense the plurality of differing exposures of electromagnetic radiation, and wherein the pixel array (2902, 2904) comprises a plurality of subsets of differing pixels; wherein each of the pixels comprises a transfer gate transistor; wherein each transfer gate transistor in one subset of pixels are electrically connected together by a TX signal; wherein the TX signal provides global operation of transfer gate transistor per subset of pixels; a memory comprising instructions for controlling the emitter so as to pulse the plurality of exposures that correspond to the plurality of subsets of differing pixels to create the image data; wherein said memory further comprises instructions that coordinate the pulses of electromagnetic radiation to be emitted during a predefined portion of a frame readout period of the image sensor during which pulse sensitive pixels are not read; wherein the system further comprises a processor which is configured to create a plurality of exposed frames from the image data, wherein each exposed frame corresponds to a different exposure; wherein the processor creates a single display frame from the plurality of exposed frames to expand dynamic range; and wherein the processor creates a stream of images by sequentially combining a plurality of display frames to provide increased dynamic range. an emitter that is configured to emit a plurality of pulses of differing wavelengths of electromagnetic radiation for providing illumination in an environment at a plurality of different exposures; an image sensor that is configured to sense the pulses of electromagnetic radiation reflected from the environment and to create image data therefrom; wherein said image sensor comprises a pixel array (2902, 2904) that is configured to sense the plurality of differing exposures of electromagnetic radiation, and wherein the pixel array (2902, 2904) comprises a plurality of subsets of differing pixels; wherein each of the pixels comprises a transfer gate transistor; wherein each transfer gate transistor in one subset of pixels are electrically connected together by a TX signal; wherein the TX signal provides global operation of transfer gate transistor per subset of pixels; a memory comprising instructions for controlling the emitter so as to pulse the plurality of exposures that correspond to the plurality of subsets of differing pixels to create the image data; wherein said memory further comprises instructions that coordinate the pulses of electromagnetic radiation to be emitted during a predefined portion of a frame readout period of the image sensor during which pulse sensitive pixels are not read; wherein the system further comprises a processor which is configured to create a plurality of exposed frames from the image data, wherein each exposed frame corresponds to a different exposure; wherein the processor creates a single display frame from the plurality of exposed frames to expand dynamic range; and wherein the processor creates a stream of images by sequentially combining a plurality of display frames to provide increased dynamic range.