A reagent analyzer, comprising: an optical imaging system configured to read reflectance signals having wavelengths of light of a first sample of a specimen combined with a reagent on a reagent pad, said reagent pad being capable of undergoing a color change in response to the presence of an analyte of interest in the specimen, and a second sample of the specimen on a non-reagent test pad, said non-reagent test pad being configured to enable determination of a color of the specimen, and to output said reflectance signals; a processor coupled to the optical imaging system and configured to receive said reflectance signals; and a non-transitory computer readable medium included in or coupled to the processor and storing computer executable code that when executed by the processor causes the processor to: analyze said reflectance signals to determine whether the analyte of interest is present in the first sample by quantifying a first predetermined property of the first sample combined with the reagent, said first predetermined property being a color of the first sample of the specimen combined with the reagent on the reagent pad analyze said reflectance signals to quantify a second predetermined property of the second sample responsive to the analyzing of the first sample indicating presence of the analyte of interest in the first sample, said second predetermined property being a color of the second sample of the specimen on the non-reagent pad; and verify a presence of the analyte of interest in the first sample based on the quantification of the first predetermined property and the second predetermined property. an optical imaging system configured to read reflectance signals having wavelengths of light of a first sample of a specimen combined with a reagent on a reagent pad, said reagent pad being capable of undergoing a color change in response to the presence of an analyte of interest in the specimen, and a second sample of the specimen on a non-reagent test pad, said non-reagent test pad being configured to enable determination of a color of the specimen, and to output said reflectance signals; a processor coupled to the optical imaging system and configured to receive said reflectance signals; and a non-transitory computer readable medium included in or coupled to the processor and storing computer executable code that when executed by the processor causes the processor to: analyze said reflectance signals to determine whether the analyte of interest is present in the first sample by quantifying a first predetermined property of the first sample combined with the reagent, said first predetermined property being a color of the first sample of the specimen combined with the reagent on the reagent pad analyze said reflectance signals to quantify a second predetermined property of the second sample responsive to the analyzing of the first sample indicating presence of the analyte of interest in the first sample, said second predetermined property being a color of the second sample of the specimen on the non-reagent pad; and verify a presence of the analyte of interest in the first sample based on the quantification of the first predetermined property and the second predetermined property. analyze said reflectance signals to determine whether the analyte of interest is present in the first sample by quantifying a first predetermined property of the first sample combined with the reagent, said first predetermined property being a color of the first sample of the specimen combined with the reagent on the reagent pad analyze said reflectance signals to quantify a second predetermined property of the second sample responsive to the analyzing of the first sample indicating presence of the analyte of interest in the first sample, said second predetermined property being a color of the second sample of the specimen on the non-reagent pad; and verify a presence of the analyte of interest in the first sample based on the quantification of the first predetermined property and the second predetermined property.