An intelligent construction system using 3D printing and additive manufacturing comprising: a printing machine comprising: - a printing head having an extrusion nozzle, and - a programmable logic controller, wherein the printing machine is connected to an external pumping device configured to feed the printing head with fresh concrete or mortar to be extruded through the extrusion nozzle according to a predefined layer pattern in a digital file executable by the programmable logic controller of the printing machine; where the printing machine is configured to continuously apply the layers of the predefined pattern until the geometry configured in the digital file is printed, and where the printing machine comprises a self-supporting structure configured as a mechanical system with a Cartesian configuration (X-Y-Z), wherein the printing machine comprises: a X axis structural profile made of steel, wherein the printing head is configured to slide across the X axis structural profile; movable steel columns which form the Z axis, wherein the movable steel columns are connected to the X axis structural profile; wherein the system also comprises: machine vision and artificial intelligence resources comprising at least one camera and/or a profilometer arranged on the printing head configured to generate and send an input signal to the programmable logic controller continuously and in real time during printing; and wherein the programmable logic controller comprises a programme or programmes configured to detect existing defects in the print bead and detect defective surfaces, characterized in that the printing machine further comprises: a continuous and modular Y axis, configured to adapt the printing range to constructions of different dimensions using the same printing head, wherein the movement along the Y axis is defined via rails, wherein the rails are modular profiles joined together, and wherein the rails are height-adjustable and width-adjustable for levelling the printing area so as form a continuous levellable surface over which the columns move synchronously. a printing machine comprising: - a printing head having an extrusion nozzle, and - a programmable logic controller, - a printing head having an extrusion nozzle, and - a programmable logic controller, wherein the printing machine is connected to an external pumping device configured to feed the printing head with fresh concrete or mortar to be extruded through the extrusion nozzle according to a predefined layer pattern in a digital file executable by the programmable logic controller of the printing machine; where the printing machine is configured to continuously apply the layers of the predefined pattern until the geometry configured in the digital file is printed, and where the printing machine comprises a self-supporting structure configured as a mechanical system with a Cartesian configuration (X-Y-Z), wherein the printing machine comprises: a X axis structural profile made of steel, wherein the printing head is configured to slide across the X axis structural profile; movable steel columns which form the Z axis, wherein the movable steel columns are connected to the X axis structural profile; a X axis structural profile made of steel, wherein the printing head is configured to slide across the X axis structural profile; movable steel columns which form the Z axis, wherein the movable steel columns are connected to the X axis structural profile; wherein the system also comprises: machine vision and artificial intelligence resources comprising at least one camera and/or a profilometer arranged on the printing head configured to generate and send an input signal to the programmable logic controller continuously and in real time during printing; and wherein the programmable logic controller comprises a programme or programmes configured to detect existing defects in the print bead and detect defective surfaces, characterized in that the printing machine further comprises: a continuous and modular Y axis, configured to adapt the printing range to constructions of different dimensions using the same printing head, wherein the movement along the Y axis is defined via rails, wherein the rails are modular profiles joined together, and wherein the rails are height-adjustable and width-adjustable for levelling the printing area so as form a continuous levellable surface over which the columns move synchronously.