A compound of Formula I such that ring A is selected from the group consisting of and wherein R 1a is hydrogen, cyano, halo, alkyl, haloalkyl, alkoxy, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, or piperidinyl; R 2 is piperidinyl substituted with 1 substituent selected from the group consisting of or R 2 is R 3 is hydrogen, halo, cyano, alkyl, haloalkyl, alkoxy, or haloalkoxy; R 4 is hydrogen, halo, cyano, alkyl, haloalkyl, alkoxy, or haloalkoxy; R 5 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 6 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 7 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 8 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 9 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 10 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, alkoxycarbonylamino, or benzyloxycarbonylamino; R 11 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, alkoxycarbonylamino, or benzyloxycarbonylamino; or R 10 and R 11 taken together is O or N-OH; provided that at least one of R 5, R 6, R 7, R 8, R 9, R 10, or R 11 is not hydrogen; Ar 1 is phenyl substituted with 0-3 substituents selected from the group consisting of cyano, halo, alkyl, haloalkyl, alkoxy, haloalkoxy, and alkylSO 2; X is O, CH 2, or NH; and Y is a bond, O, CH 2, or NH; or a pharmaceutically acceptable salt thereof. R 1a is hydrogen, cyano, halo, alkyl, haloalkyl, alkoxy, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, or piperidinyl; R 2 is piperidinyl substituted with 1 substituent selected from the group consisting of or R 2 is R 3 is hydrogen, halo, cyano, alkyl, haloalkyl, alkoxy, or haloalkoxy; R 4 is hydrogen, halo, cyano, alkyl, haloalkyl, alkoxy, or haloalkoxy; R 5 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 6 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 7 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 8 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 9 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, or dialkylamino; R 10 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, alkoxycarbonylamino, or benzyloxycarbonylamino; R 11 is hydrogen, hydroxy, alkoxy, haloalkoxy, azido, amino, alkylamino, dialkylamino, azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, alkoxycarbonylamino, or benzyloxycarbonylamino; or R 10 and R 11 taken together is O or N-OH; provided that at least one of R 5, R 6, R 7, R 8, R 9, R 10, or R 11 is not hydrogen; Ar 1 is phenyl substituted with 0-3 substituents selected from the group consisting of cyano, halo, alkyl, haloalkyl, alkoxy, haloalkoxy, and alkylSO 2; X is O, CH 2, or NH; and Y is a bond, O, CH 2, or NH; or a pharmaceutically acceptable salt thereof.