A compound represented by Formula, or a pharmaceutically acceptable salt thereof wherein: ring A is cycloalkyl, aryl, heteroaryl, or heterocycloalkyl; ring B is cycloalkyl, aryl, heteroaryl, or heterocycloalkyl; R 1 is H, halo, alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, haloalkyl, cyano, -SR c, -C R c, -C OR c, -C N(R c)(R d), -N(R c)(R d), - (C(R g) 2) q -N(R c)(R d), -OR c, or -(C(R g) 2) q -OR c; R c and R d are each independently H, alkyl, cycloalkyl, aryl, heterocycloalkyl, or heteroaryl; or R c and R d, taken together with the atom to which they are attached, form a substituted or unsubstituted heterocycloalkyl; each q is independently an integer from 1-3; R g is H or alkyl; R 2V and R 2W are each independently H, halo, hydroxy, alkyl, cycloalkyl, heterocycloalkyl, alkoxy, alkoxyalkyl, or amino; or R 2V and R 2W, taken together with the atom to which they are attached, form a cycloalkyl or heterocycloalkyl; L 1 is absent, -N(R e)-, -CH 2 N(R e)-, -CH 2 CH 2 N(R e)-, or alkylene, provided that if L 1 is -CH 2 N(R e)- or -CH 2 CH 2 N(R e)-, then ring B is attached to carbon terminus of the substituent and R 3 is attached to the nitrogen terminus of the substituent; where R e is H or alkyl; or R e is covalently bound to a position on ring B, thereby forming a heteroaryl or heterocycloalkyl ring structure, which is unsubstituted or substituted; R 3 is wherein R f1 is H, halo, alkyl or cyano; R f2 and R f3 are each independently H, halo, alkyl, cycloalkyl, heterocycloalkyl, heteroaryl, aryl, alkoxy, alkoxyalkyl, -N(R c')(R d'), or -(C(R g') 2) q -N(R c')(R d'); each R g' is independently H or alkyl; R c' and R d' are each independently H, alkyl, heterocycloalkyl, alkoxy or alkoxyalkyl; or R c' and R d', taken together with the atom to which they are attached, form a substituted or unsubstituted heterocycloalkyl, each R a is independently H, halo, hydroxyl, nitro, or cyano; or is alkyl, alkoxy, alkoxyalkyl, amino, haloalkyl, aryl, heteroaryl, heterocycloalkyl or cycloalkyl, which is unsubstituted or substituted; each R b is independently H, halo, hydroxyl, nitro, or cyano, or is alkyl, alkoxy, alkoxyalkyl, amino, haloalkyl, aryl, heteroaryl, heterocycloalkyl, cycloalkyl or -NR h R j, which is unsubstituted or substituted; R h and R j are each independently H, alkyl, -N(R h')(R j'), -(C(R g') 2) q -N(R h')(R j'), or heterocycloalkyl, R h' and R j' are each independently H or alkyl; or R h' and R j', taken together with the atom to which they are attached, form a unsubstituted or substituted heterocycloalkyl; and m and n are integers each independently selected from 1 to 4. ring A is cycloalkyl, aryl, heteroaryl, or heterocycloalkyl; ring B is cycloalkyl, aryl, heteroaryl, or heterocycloalkyl; R 1 is H, halo, alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, haloalkyl, cyano, -SR c, -C R c, -C OR c, -C N(R c)(R d), -N(R c)(R d), - (C(R g) 2) q -N(R c)(R d), -OR c, or -(C(R g) 2) q -OR c; R c and R d are each independently H, alkyl, cycloalkyl, aryl, heterocycloalkyl, or heteroaryl; or R c and R d, taken together with the atom to which they are attached, form a substituted or unsubstituted heterocycloalkyl; each q is independently an integer from 1-3; R g is H or alkyl; R 2V and R 2W are each independently H, halo, hydroxy, alkyl, cycloalkyl, heterocycloalkyl, alkoxy, alkoxyalkyl, or amino; or R 2V and R 2W, taken together with the atom to which they are attached, form a cycloalkyl or heterocycloalkyl; L 1 is absent, -N(R e)-, -CH 2 N(R e)-, -CH 2 CH 2 N(R e)-, or alkylene, provided that if L 1 is -CH 2 N(R e)- or -CH 2 CH 2 N(R e)-, then ring B is attached to carbon terminus of the substituent and R 3 is attached to the nitrogen terminus of the substituent; where R e is H or alkyl; or R e is covalently bound to a position on ring B, thereby forming a heteroaryl or heterocycloalkyl ring structure, which is unsubstituted or substituted; R 3 is wherein R f1 is H, halo, alkyl or cyano; R f2 and R f3 are each independently H, halo, alkyl, cycloalkyl, heterocycloalkyl, heteroaryl, aryl, alkoxy, alkoxyalkyl, -N(R c')(R d'), or -(C(R g') 2) q -N(R c')(R d'); each R g' is independently H or alkyl; R c' and R d' are each independently H, alkyl, heterocycloalkyl, alkoxy or alkoxyalkyl; or R c' and R d', taken together with the atom to which they are attached, form a substituted or unsubstituted heterocycloalkyl, each R a is independently H, halo, hydroxyl, nitro, or cyano; or is alkyl, alkoxy, alkoxyalkyl, amino, haloalkyl, aryl, heteroaryl, heterocycloalkyl or cycloalkyl, which is unsubstituted or substituted; each R b is independently H, halo, hydroxyl, nitro, or cyano, or is alkyl, alkoxy, alkoxyalkyl, amino, haloalkyl, aryl, heteroaryl, heterocycloalkyl, cycloalkyl or -NR h R j, which is unsubstituted or substituted; R h and R j are each independently H, alkyl, -N(R h')(R j'), -(C(R g') 2) q -N(R h')(R j'), or heterocycloalkyl, R h' and R j' are each independently H or alkyl; or R h' and R j', taken together with the atom to which they are attached, form a unsubstituted or substituted heterocycloalkyl; and m and n are integers each independently selected from 1 to 4.