A respiration measurement device comprising: a first body configured to have an air flow path formed therein to allow air generated by respiration of a user to be introduced thereinto and moved therethrough, a part of the air flow path being opened to form an opening; a second body comprising a respiration measurement unit configured to measure a pressure of the air moved through the air flow path, path, formed to be detachably coupled to the first body and installed to close the opening formed through the first body, wherein the respiration measurement unit comprises: a respiration measurement sensor module formed to correspond to the opening of the air flow path and installed to close the opening of the air flow path by coupling between the first body and the second body; and a first differential pressure generation block as a member having a designated thickness and height, disposed at the center of the respiration measurement sensor module and configured to extend from the respiration measurement sensor module towards an inner center of the air flow path and the respiration measurement device further comprising: a second differential pressure generation block as a member having a designated thickness and height, formed to correspond to the first differential pressure generation block, disposed on the inner surface of the air flow path, configured to extend from an inner surface of the air flow path towards the inner center of the air flow path, and disposed opposite the first differential pressure generation block so as to correspond to the first differential pressure generation block; and the respiration measurement unit further comprising a mouthpiece detachably coupled to an inlet side of the air flow path. a first body configured to have an air flow path formed therein to allow air generated by respiration of a user to be introduced thereinto and moved therethrough, a part of the air flow path being opened to form an opening; a second body comprising a respiration measurement unit configured to measure a pressure of the air moved through the air flow path, path, formed to be detachably coupled to the first body and installed to close the opening formed through the first body, wherein the respiration measurement unit comprises: a respiration measurement sensor module formed to correspond to the opening of the air flow path and installed to close the opening of the air flow path by coupling between the first body and the second body; and a first differential pressure generation block as a member having a designated thickness and height, disposed at the center of the respiration measurement sensor module and configured to extend from the respiration measurement sensor module towards an inner center of the air flow path and the respiration measurement device further comprising: a second differential pressure generation block as a member having a designated thickness and height, formed to correspond to the first differential pressure generation block, disposed on the inner surface of the air flow path, configured to extend from an inner surface of the air flow path towards the inner center of the air flow path, and disposed opposite the first differential pressure generation block so as to correspond to the first differential pressure generation block; and the respiration measurement unit further comprising a mouthpiece detachably coupled to an inlet side of the air flow path. a respiration measurement sensor module formed to correspond to the opening of the air flow path and installed to close the opening of the air flow path by coupling between the first body and the second body; and a first differential pressure generation block as a member having a designated thickness and height, disposed at the center of the respiration measurement sensor module and configured to extend from the respiration measurement sensor module towards an inner center of the air flow path and the respiration measurement device further comprising: a second differential pressure generation block as a member having a designated thickness and height, formed to correspond to the first differential pressure generation block, disposed on the inner surface of the air flow path, configured to extend from an inner surface of the air flow path towards the inner center of the air flow path, and disposed opposite the first differential pressure generation block so as to correspond to the first differential pressure generation block; and the respiration measurement unit further comprising a mouthpiece detachably coupled to an inlet side of the air flow path. a second differential pressure generation block as a member having a designated thickness and height, formed to correspond to the first differential pressure generation block, disposed on the inner surface of the air flow path, configured to extend from an inner surface of the air flow path towards the inner center of the air flow path, and disposed opposite the first differential pressure generation block so as to correspond to the first differential pressure generation block; and the respiration measurement unit further comprising a mouthpiece detachably coupled to an inlet side of the air flow path.