mhurhangee/ep-ind-claims huggingface dataset:
A compound of Formula: wherein: R 1 is C 1 -C 3 alkyl or C 3 -C 6 cycloalkyl, wherein the alkyl or cycloalkyl is optionally substituted with one to three halogen atoms; R 2 is hydrogen or C 1 -C 6 alkyl wherein the alkyl is optionally substituted with halo. R 3 is hydrogen or C 1 -C 3 alkyl; R 4 is hydrogen or C 1 -C 3 alkyl; R 5 is hydrogen, C 1 -C 3 alkyl, OR a or -NHR a; R 6 is hydrogen, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, or C 3 -C 6 cycloalkyl wherein the cycloalkyl is optionally substituted with C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, or 1 or 2 halogen atoms; R a and R b are independently hydrogen, C 1 -C 3 alkyl or R a and R b combine with the nitrogen atom to which they are attached to form a four to six member heterocyclic ring optionally containing an oxygen or a nitrogen atom in the ring; or a pharmaceutically acceptable salt or stereoisomerthereof. R 1 is C 1 -C 3 alkyl or C 3 -C 6 cycloalkyl, wherein the alkyl or cycloalkyl is optionally substituted with one to three halogen atoms; R 2 is hydrogen or C 1 -C 6 alkyl wherein the alkyl is optionally substituted with halo. R 3 is hydrogen or C 1 -C 3 alkyl; R 4 is hydrogen or C 1 -C 3 alkyl; R 5 is hydrogen, C 1 -C 3 alkyl, OR a or -NHR a; R 6 is hydrogen, C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, or C 3 -C 6 cycloalkyl wherein the cycloalkyl is optionally substituted with C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, or 1 or 2 halogen atoms; R a and R b are independently hydrogen, C 1 -C 3 alkyl or R a and R b combine with the nitrogen atom to which they are attached to form a four to six member heterocyclic ring optionally containing an oxygen or a nitrogen atom in the ring;
A coil of a conductive wire having a quadrangular cross section, the conductive wire being wound in a rectangular shape and laminated to have a series of turns including first to n-th turns, where n is an integer of 3 or more, and each of turns have four coil sides, the conductive wire being provided, on at least some of the first to n-th turns in the coil, with recesses (5e, 5f, 5g, 5h) that is deformed in a recess shape so as to have a shape different from a shape of another portion of the conductive wire, characterized in that: the recesses (5e, 5f, 5g, 5h) are formed on an inside of a turn and on an outside of the turn, the turn being each of the at least some of the first to n-th turns, the recesses (5e, 5g) on the inside of the turn and the recesses (5f, 5h) on the outside of the turn are not provided at positions identical to each other in a Z-axis direction representing a direction perpendicular to radial directions and circumferential directions of the coil. the recesses (5e, 5f, 5g, 5h) are formed on an inside of a turn and on an outside of the turn, the turn being each of the at least some of the first to n-th turns, the recesses (5e, 5g) on the inside of the turn and the recesses (5f, 5h) on the outside of the turn are not provided at positions identical to each other in a Z-axis direction representing a direction perpendicular to radial directions and circumferential directions of the coil.
A method for communication in a wireless telecommunication system that employs Time Division Duplex, TDD, carrier aggregation, the method comprising: multiplexing, by a network element, at least one symbol of a physical hybrid automatic repeat request, HARQ, indicator channel, PHICH, onto at least one resource element of a physical control format indicator channel, PCFICH, such that the at least one resource element is shared by the PHICH and PCFICH by overlaying PHICH transmission and PCFICH transmission in a control region in which a resource for the PHICH is not reserved.
A method of controlling a positioning control apparatus configured to perform machining while pressing a tip end of a machining tool against a predetermined position on a machined surface of a workpiece, the machining tool being attached to an arm tip of the positioning control apparatus, the method comprising the steps of deriving a predetermined relational expression before the machining, the relational expression defining a relation between a sideslip amount of the tip end of the machining tool in a second direction with respect to pressing force generated when the tip end of the machining tool is pressed against the predetermined position in a first direction in a state where the tip end of the machining tool coincides with the predetermined position and a sideslip amount of the tip end of the machining tool in the second direction with respect to maximum pressing force, the second direction being parallel to the machined surface of the workpiece, the first direction being perpendicular to the machined surface of the workpiece, the maximum pressing force being set to force that is equal to or more than machining reaction force; detecting the pressing force during the machining by a force sensor; calculating the sideslip amount corresponding to the pressing force detected by the force sensor, in accordance with the predetermined relational expression at any time; correcting a position command value of the arm tip of the positioning control apparatus based on the calculated sideslip amount; and machining the workpiece while moving the arm tip of the positioning control apparatus in accordance with the corrected position command value. deriving a predetermined relational expression before the machining, the relational expression defining a relation between a sideslip amount of the tip end of the machining tool in a second direction with respect to pressing force generated when the tip end of the machining tool is pressed against the predetermined position in a first direction in a state where the tip end of the machining tool coincides with the predetermined position and a sideslip amount of the tip end of the machining tool in the second direction with respect to maximum pressing force, the second direction being parallel to the machined surface of the workpiece, the first direction being perpendicular to the machined surface of the workpiece, the maximum pressing force being set to force that is equal to or more than machining reaction force; detecting the pressing force during the machining by a force sensor; calculating the sideslip amount corresponding to the pressing force detected by the force sensor, in accordance with the predetermined relational expression at any time; correcting a position command value of the arm tip of the positioning control apparatus based on the calculated sideslip amount; and machining the workpiece while moving the arm tip of the positioning control apparatus in accordance with the corrected position command value.
A hub unit configured to be posed between a vehicular wheel and a vehicular body and configured to support said vehicular wheel relative to said vehicular body rotatably, comprising: an outer member having an inner circumferential surface having an annular raceway surface (31A1, 31A2); an inner member (32, 33) disposed radially inner than said outer member and having an annular raceway surface (32A, 33A) opposite to said raceway surface (31A1, 31A2) of said outer member; and a plurality of rolling elements disposed in contact with said raceway surface (31A1, 31A2) of said outer member and said raceway surface (32A, 33A) of said inner member (32, 33) on an annular raceway, characterized by said rolling element being configured of a sintered body that contains as a main component a β-sialon represented by a compositional formula of Si 6-Z Al Z O Z N 8-Z and satisfying 0.1 ≤ z ≤ 3.5 and has a remainder formed of an impurity, said rolling element having a rolling contact surface serving as a surface contacting said outer member and said inner member (32, 33), said rolling contact surface being included in a portion having a high density layer (34B, 34D) higher in density than an inner portion, wherein said high density layer (34B, 34D) has a surface included in a portion having a higher density layer higher in density than another portion of said high density layer (34B, 34D). an outer member having an inner circumferential surface having an annular raceway surface (31A1, 31A2); an inner member (32, 33) disposed radially inner than said outer member and having an annular raceway surface (32A, 33A) opposite to said raceway surface (31A1, 31A2) of said outer member; and a plurality of rolling elements disposed in contact with said raceway surface (31A1, 31A2) of said outer member and said raceway surface (32A, 33A) of said inner member (32, 33) on an annular raceway,
Membrane for compensating for the pressure difference between the exterior and the interior of a free ink reservoir of a pen or the like (10, 110), said membrane comprising a first part having a first stiffness, and a second part having a second stiffness, the first stiffness being lower than the second stiffness, characterized in that a weight is arranged between the first part and the second part.
A biological fluid separation device adapted to receive a multi-component blood sample, the biological fluid separation device comprising: a housing having an inlet port, a flow channel, and an outlet port, the inlet port and the outlet port in fluid communication via the flow channel; a filter; a first reservoir defined within the flow channel between the inlet port and the filter; and a second reservoir defined within the flow channel between the filter and the outlet port, wherein the filter is disposed between the first reservoir and the second reservoir and is adapted to trap a first portion of the multi-component blood sample within the first reservoir and to allow a second portion of the multi-component blood sample to pass through the filter and into the second reservoir, characterized in that the flow channel comprises a loop such that the first portion of the multi-component blood sample is recirculated through the flow channel. a housing having an inlet port, a flow channel, and an outlet port, the inlet port and the outlet port in fluid communication via the flow channel; a filter; a first reservoir defined within the flow channel between the inlet port and the filter; and a second reservoir defined within the flow channel between the filter and the outlet port, wherein the filter is disposed between the first reservoir and the second reservoir and is adapted to trap a first portion of the multi-component blood sample within the first reservoir and to allow a second portion of the multi-component blood sample to pass through the filter and into the second reservoir, characterized in that the flow channel comprises a loop such that the first portion of the multi-component blood sample is recirculated through the flow channel.
A compound that is an MDM2 inhibitor and that constitutes a cis-imidazoline for use in the treatment of osteoarthritis, wherein the compound is administered directly to an osteoarthritic joint, or wherein the compound is administered in at least two treatment cycles wherein each treatment cycle independently comprises a treatment course of from 1 day to 3 months followed by a non-treatment interval of at least two weeks.
A positive electrode active material for a secondary battery, comprising a composite coating layer formed on a surface of lithium composite transition metal oxide particles, wherein the composite coating layer includes a ferroelectric material and a boron-based oxide including boron, wherein the lithium composite transition metal oxide is represented by the following Chemical Formula 4: [Chemical Formula 4] Li a Ni 1-b-c-d Co b Mn c Q d O 2+δ wherein, in Chemical Formula 4, Q is one or more elements selected from the group consisting of Al, Si, B, W, Mo, Mg, V, Ti, Zn, Ga, In, Ru, Nb, Ta, Sn, Sr, La, Ce, Pr, and Zr, and 1.0<a<1.5, 0≤b≤0.4, 0≤c≤0.4, 0≤d≤0.1, 0≤b+c+d≤0.4, and -0.1≤δ≤1.0; and wherein the ferroelectric material includes a perovskite structure oxide represented by the following Chemical Formula 1: [Chemical Formula 1] Ba 1-x A x Ti 1-y B y O 3, wherein, in Chemical Formula 1, A is one or more selected from the group consisting of Pb, Sr, Ca, K, Na, and Cd, B is one or more selected from the group consisting of Sn, Hf, Zr, Ce, Nb, and Th, and 0≤x≤1.0, and 0≤y≤1.0. wherein the lithium composite transition metal oxide is represented by the following Chemical Formula 4: [Chemical Formula 4] Li a Ni 1-b-c-d Co b Mn c Q d O 2+δ wherein, in Chemical Formula 4, Q is one or more elements selected from the group consisting of Al, Si, B, W, Mo, Mg, V, Ti, Zn, Ga, In, Ru, Nb, Ta, Sn, Sr, La, Ce, Pr, and Zr, and 1.0<a<1.5, 0≤b≤0.4, 0≤c≤0.4, 0≤d≤0.1, 0≤b+c+d≤0.4, and -0.1≤δ≤1.0; and wherein the ferroelectric material includes a perovskite structure oxide represented by the following Chemical Formula 1: [Chemical Formula 1] Ba 1-x A x Ti 1-y B y O 3, wherein, in Chemical Formula 1, A is one or more selected from the group consisting of Pb, Sr, Ca, K, Na, and Cd, B is one or more selected from the group consisting of Sn, Hf, Zr, Ce, Nb, and Th, and 0≤x≤1.0, and 0≤y≤1.0.
An arrangement for influencing and/or detecting magnetic particles in a region of action, which arrangement comprises: - selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, - drive means for changing the position in space of the two sub-zones (301, 302) in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, - receiving means for acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone (301, 302), characterised in that the selection means and/or the drive means and/or the receiving means comprises at least partially a litz wire, wherein the litz wire comprises a plurality of first order litz wires comprising a plurality of individual wires, each individual wire being surrounded by an electrically high resistive material, and wherein the litz wire further comprises a plurality of second order litz wires, wherein the second order litz wires comprise a plurality of first order litz wires. - selection means for generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action, - drive means for changing the position in space of the two sub-zones (301, 302) in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, - receiving means for acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone (301, 302), characterised in that the selection means and/or the drive means and/or the receiving means comprises at least partially a litz wire, wherein the litz wire comprises a plurality of first order litz wires comprising a plurality of individual wires, each individual wire being surrounded by an electrically high resistive material, and wherein the litz wire further comprises a plurality of second order litz wires, wherein the second order litz wires comprise a plurality of first order litz wires.
A method for nucleotide sequencing comprising: a) providing a reaction mixture having: (i) a polymerase enzyme, (ii) polymerase reaction conditions including cofactors, and (iii) polymerase reaction substrates including a primed template and nucleotides, such that a reaction comprising incorporation of the nucleotides into a growing nucleic acid occurs; b) observing the reaction mixture to determine the incorporation of nucleotides into the growing nucleic acid; wherein the polymerase enzyme, the polymerase reaction conditions, and the polymerase reaction substrates are selected such that the reaction exhibits two kinetically observable steps, each of which kinetically observable steps comprise steps after nucleotide binding through the step of product release or each of which kinetically observable steps comprise steps after product release through nucleotide binding, wherein the two kinetically observable steps produce respectively a distribution of pulse widths or a distribution of time between pulse widths described by a double exponential equation; and c) using the observed incorporation of nucleotides to determine a sequence of the template. a) providing a reaction mixture having: (i) a polymerase enzyme, (ii) polymerase reaction conditions including cofactors, and (iii) polymerase reaction substrates including a primed template and nucleotides, such that a reaction comprising incorporation of the nucleotides into a growing nucleic acid occurs; b) observing the reaction mixture to determine the incorporation of nucleotides into the growing nucleic acid; wherein the polymerase enzyme, the polymerase reaction conditions, and the polymerase reaction substrates are selected such that the reaction exhibits two kinetically observable steps, each of which kinetically observable steps comprise steps after nucleotide binding through the step of product release or each of which kinetically observable steps comprise steps after product release through nucleotide binding, wherein the two kinetically observable steps produce respectively a distribution of pulse widths or a distribution of time between pulse widths described by a double exponential equation; and c) using the observed incorporation of nucleotides to determine a sequence of the template.
A Wi-Fi location server system, comprising: a collection of information in a database describing observed Wi-Fi access points for at least one target area, the collection including information for a plurality of observed Wi-Fi access points in the target area, the information including identification information for a corresponding Wi-Fi access point and calculated position information for the corresponding Wi-Fi access point, wherein the calculated position information is obtained from recording multiple readings of the Wi-Fi access point at locations distributed around more than one side of the Wi-Fi access point to reduce arterial bias in the calculated position information; computer-implemented logic for receiving readings for observed Wi-Fi access points in the target area and associated locations at which the readings were detected; computer-implemented logic for identifying potential error in the locations, the logic for identifying potential error including logic to determine a cluster and to identify locations that are outliers of the cluster as having potential error; and computer-implemented logic to determine calculated positions for observed Wi-Fi access points based on the readings, wherein the locations with potential error are excluded from use in the determination. a collection of information in a database describing observed Wi-Fi access points for at least one target area, the collection including information for a plurality of observed Wi-Fi access points in the target area, the information including identification information for a corresponding Wi-Fi access point and calculated position information for the corresponding Wi-Fi access point, wherein the calculated position information is obtained from recording multiple readings of the Wi-Fi access point at locations distributed around more than one side of the Wi-Fi access point to reduce arterial bias in the calculated position information; computer-implemented logic for receiving readings for observed Wi-Fi access points in the target area and associated locations at which the readings were detected; computer-implemented logic for identifying potential error in the locations, the logic for identifying potential error including logic to determine a cluster and to identify locations that are outliers of the cluster as having potential error; and computer-implemented logic to determine calculated positions for observed Wi-Fi access points based on the readings, wherein the locations with potential error are excluded from use in the determination.
An information processing device comprising: abnormality detection means for detecting abnormality of a certain device; characterized in that further comprising degree calculation means and difference calculation means, wherein the degree calculation means is configured to calculate a degree of conformity an observation information and a prediction information, the observation information observed for a system suffering an effect of the certain device and representing a state of the system, the prediction information predicted in accordance with a model for a state of the system and representing a predicted state of the system; the difference calculation means configured to calculate a difference, when the degree of conformity calculated by the degree calculation unit satisfies a predetermined calculation condition, between an amount of manipulation instructed to the certain device and an operation amount predicted to be performed by the certain device when the amount of manipulation is instructed to the certain device based on an input model of the certain device; and the abnormality detection means configured to determine that abnormality of the certain device occurs when the difference satisfies a predetermined determination condition. abnormality detection means for detecting abnormality of a certain device; characterized in that further comprising degree calculation means and difference calculation means, wherein the degree calculation means is configured to calculate a degree of conformity an observation information and a prediction information, the observation information observed for a system suffering an effect of the certain device and representing a state of the system, the prediction information predicted in accordance with a model for a state of the system and representing a predicted state of the system; the difference calculation means configured to calculate a difference, when the degree of conformity calculated by the degree calculation unit satisfies a predetermined calculation condition, between an amount of manipulation instructed to the certain device and an operation amount predicted to be performed by the certain device when the amount of manipulation is instructed to the certain device based on an input model of the certain device; and the abnormality detection means configured to determine that abnormality of the certain device occurs when the difference satisfies a predetermined determination condition.