A method for direct printing plate-making by ink-jet printing, comprising: spraying a UV-curable ink through an inkjet printer onto surface of a blank substrate or a substrate with coating to form images, so as to obtain a sprayed blank substrate or a sprayed substrate with coating, and curing the sprayed blank substrate or the sprayed substrate with coating under ultraviolet light with a wavelength in range of 300-450 nm for 1-60 s, so as to obtain a printing plate, wherein, based on total weight of the UV-curable ink, the UV-curable ink consists of: monomer with UV-reactive groups 20-90 wt% acrylate-based prepolymer 1-40 wt% photoinitiator 0.1-5 wt% colorant 0.01-5 wt% dispersant balance the monomer with UV-reactive groups is at least one selected from the group consisting of acryloylmorpholine, mono-functional acrylate-based monomer, bi-functional acrylate-based monomer, and multi-functional acrylate-based monomer, the mono-functional acrylate-based monomer is at least one selected from the group consisting of hydroxyethyl acrylate, hydroxypropyl acrylate, lauryl acrylate, octadecyl acrylate, 2-ethylhexyl acrylate, butyl acrylate, ethoxylated cyclohexyl acrylate, isobornyl acrylate, epoxy acrylate, ethyl ethoxy-acrylate, neopentyl glycol benzoate acrylate, 2-phenoxy-ethyl methacrylate, and nonyl-phenoxy polyethylene glycol acrylate; the bi-functional acrylate-based monomer is at least one selected from the group consisting of polyethylene glycol diacrylate, polyethylene glycol diacrylate, polyethylene glycol diacrylate, tripropylene glycol diacrylate, dipropylene glycol diacrylate, propylene glycol diacrylate, neopentyl glycol diacrylate, propoxylated neopentyl glycol diacrylate, 1,3-butanediol diacrylate, phthalate diglycol diacrylate, phthalate tripropylene glycol diacrylate, ethylene glycol diacrylate, diethylene glycol diacrylate, triethylene glycol diacrylate, tetraethylene glycol diacrylate, 1,6-hexanediol diacrylate, ethoxylated 1,6-hexanediol diacrylate, 1,4-butanediol diacrylate, and ethoxylated bisphenol A diacrylate; the multi-functional acrylate-based monomer is at least one selected from the group consisting of trimethylolpropane triacrylate, ethylene oxide-modified trimethylolpropane triacrylate, ethoxylated trimethylolpropane triacrylate, propoxylated trimethylolpropane triacrylate, propoxylated glycerol triacrylate, pentaerythritol tetraacrylate, pentaerythritol triacrylate, and dipentaerythritol pentaacrylate. spraying a UV-curable ink through an inkjet printer onto surface of a blank substrate or a substrate with coating to form images, so as to obtain a sprayed blank substrate or a sprayed substrate with coating, and curing the sprayed blank substrate or the sprayed substrate with coating under ultraviolet light with a wavelength in range of 300-450 nm for 1-60 s, so as to obtain a printing plate, wherein, based on total weight of the UV-curable ink, the UV-curable ink consists of: monomer with UV-reactive groups 20-90 wt% acrylate-based prepolymer 1-40 wt% photoinitiator 0.1-5 wt% colorant 0.01-5 wt% dispersant balance the monomer with UV-reactive groups is at least one selected from the group consisting of acryloylmorpholine, mono-functional acrylate-based monomer, bi-functional acrylate-based monomer, and multi-functional acrylate-based monomer, the mono-functional acrylate-based monomer is at least one selected from the group consisting of hydroxyethyl acrylate, hydroxypropyl acrylate, lauryl acrylate, octadecyl acrylate, 2-ethylhexyl acrylate, butyl acrylate, ethoxylated cyclohexyl acrylate, isobornyl acrylate, epoxy acrylate, ethyl ethoxy-acrylate, neopentyl glycol benzoate acrylate, 2-phenoxy-ethyl methacrylate, and nonyl-phenoxy polyethylene glycol acrylate; the bi-functional acrylate-based monomer is at least one selected from the group consisting of polyethylene glycol diacrylate, polyethylene glycol diacrylate, polyethylene glycol diacrylate, tripropylene glycol diacrylate, dipropylene glycol diacrylate, propylene glycol diacrylate, neopentyl glycol diacrylate, propoxylated neopentyl glycol diacrylate, 1,3-butanediol diacrylate, phthalate diglycol diacrylate, phthalate tripropylene glycol diacrylate, ethylene glycol diacrylate, diethylene glycol diacrylate, triethylene glycol diacrylate, tetraethylene glycol diacrylate, 1,6-hexanediol diacrylate, ethoxylated 1,6-hexanediol diacrylate, 1,4-butanediol diacrylate, and ethoxylated bisphenol A diacrylate; the multi-functional acrylate-based monomer is at least one selected from the group consisting of trimethylolpropane triacrylate, ethylene oxide-modified trimethylolpropane triacrylate, ethoxylated trimethylolpropane triacrylate, propoxylated trimethylolpropane triacrylate, propoxylated glycerol triacrylate, pentaerythritol tetraacrylate, pentaerythritol triacrylate, and dipentaerythritol pentaacrylate.