mhurhangee/ep-ind-claims huggingface dataset:
A solid dispersion, which comprises a glucokinase activator or isotope labeled glucokinase activator thereof or pharmaceutically acceptable salts thereof and polymer carriers, wherein the glucokinase activator is selected from the group consisting of: HMS5552 or isotope labeled analogues thereof or pharmaceutically acceptable salts thereof, wherein the glucokinase activator preferably is the compound HMS5552, or isotope labeled analogues or pharmaceutically acceptable salts thereof, and wherein the polymer carriers are selected from the group consisting of copolymer of butyl methacrylate, dimethylaminoethyl methacrylate and methyl methacrylate (1:2:1), copolymer of methacrylic acid and ethyl acrylate (1:1), copolymer of methacrylic acid and methyl methacrylate (1:2), copolymer of ethyl acrylate, methyl methacrylate and chlorotrimethylamino ethyl methacrylate (1:2:0.2), copolymer of ethyl acrylate, methyl methacrylate and chlorotrimethylamino ethyl methacrylate (1:2:0.1), copolymer of ethyl acrylate and methyl methacrylate (2:1), copolymer of methacrylic acid and butyl acrylate (35:65), polymer of methacrylic acid and methyl methacrylate (1:1), and copolymer of methacrylic acid and methyl methacrylate (35:65), wherein the polymer carrier is preferably Eudragit ®, wherein the polymer carrier more preferably is Eudragit ® L100, wherein optionally the weight ratio of the glucokinase activator to polymer carriers is selected from 1:10 to 10:1, preferably 1:9 to 9:1, 1:4 to 4:1, 3:7 to 7:3, 2:3 to 3:2, 3:4 to 4:3, 4:5 to 5:4, or 5:6 to 6:5. wherein the glucokinase activator is selected from the group consisting of: HMS5552 or isotope labeled analogues thereof or pharmaceutically acceptable salts thereof, wherein the glucokinase activator preferably is the compound HMS5552, or isotope labeled analogues or pharmaceutically acceptable salts thereof, and wherein the polymer carriers are selected from the group consisting of copolymer of butyl methacrylate, dimethylaminoethyl methacrylate and methyl methacrylate (1:2:1), copolymer of methacrylic acid and ethyl acrylate (1:1), copolymer of methacrylic acid and methyl methacrylate (1:2), copolymer of ethyl acrylate, methyl methacrylate and chlorotrimethylamino ethyl methacrylate (1:2:0.2), copolymer of ethyl acrylate, methyl methacrylate and chlorotrimethylamino ethyl methacrylate (1:2:0.1), copolymer of ethyl acrylate and methyl methacrylate (2:1), copolymer of methacrylic acid and butyl acrylate (35:65), polymer of methacrylic acid and methyl methacrylate (1:1), and copolymer of methacrylic acid and methyl methacrylate (35:65), wherein the polymer carrier is preferably Eudragit ®, wherein the polymer carrier more preferably is Eudragit ® L100, wherein optionally the weight ratio of the glucokinase activator to polymer carriers is selected from 1:10 to 10:1, preferably 1:9 to 9:1, 1:4 to 4:1, 3:7 to 7:3, 2:3 to 3:2, 3:4 to 4:3, 4:5 to 5:4, or 5:6 to 6:5.
A cosmetic composition comprising a recombinant α-neurotoxin lacking a fifth disulfide bond in loop II of the three finger fold and a transdermal system, wherein said α-neurotoxin exhibits a K D for the alpha-1-containing, human muscular nAChR that is at least 100-fold less than its K D for any of the neuronal nAChR comprising α7nAChR, α3nAChR, α4nAChR, and α2nAChR.
Apparatus for transferring energy and data between a control unit and a position measuring device by means of a line pair, wherein energy is transferred in a charging mode and data is transferred in a communication mode, wherein an energy store is provided in the position measuring device, said energy store being able to be charged in the charging mode by means of the line pair and being able to be used to supply the position measuring device with energy in the communication mode, and, in the control unit, a charging unit is provided, as well as switching means (120.1, 120.2; 200.1, 200.2, 200.3, 200.4), by means of which switching means the charging unit is able to be connected using two poles to the line pair in the charging mode, wherein, in the charging unit, a charging control unit is arranged, as well as switching elements (200.1, 200.2, 200.3, 200.4), which switching elements are able to be driven by the charging control unit in such a way that the voltage of a voltage source is able to be output in two polarities to charge the energy store, characterized in that a zero crossing detector is arranged in the charging unit, said zero crossing detector being able to be used to determine a current zero crossing of the charge current (i L) and to signal said current zero crossing of the charge current to the charging control unit.
A method comprising the steps of: additively manufacturing a shell of a wax mold; additively manufacturing a core of the wax mold; assembling the shell of the wax mold and the core of the wax mold utilizing a non-line-of-sight feature of the core to position the core within the shell; placing wax material into the wax mold and allowing the wax material to solidify to obtain a wax model; removing the shell of the wax mold from the wax model while maintaining the core in the wax material; refining the wax model by tooling a refinement into the wax material subsequent to removing the shell of the wax mold from the wax model; forming a shell of a casting mold about the wax model subsequent to refining the wax model; melting or vaporizing the wax material out of the casting mold; and pouring a material of a workpiece into a cavity of the casting mold and allowing the material of the workpiece to solidify. additively manufacturing a shell of a wax mold; additively manufacturing a core of the wax mold; assembling the shell of the wax mold and the core of the wax mold utilizing a non-line-of-sight feature of the core to position the core within the shell; placing wax material into the wax mold and allowing the wax material to solidify to obtain a wax model; removing the shell of the wax mold from the wax model while maintaining the core in the wax material; refining the wax model by tooling a refinement into the wax material subsequent to removing the shell of the wax mold from the wax model; forming a shell of a casting mold about the wax model subsequent to refining the wax model; melting or vaporizing the wax material out of the casting mold; and pouring a material of a workpiece into a cavity of the casting mold and allowing the material of the workpiece to solidify.
A polyethylene film consisting of a: heterogeneously branched ethylene/α-olefin copolymer, wherein said heterogeneously branched ethylene/α-olefin copolymer having a density in the range of 0.910 to 0.930 g/cm 3, a molecular weight distribution in the range of 2.8 to 3.8, a melt index (I 2) in the range of 0.3 to 4 g/10 min, and an I 10 /I 2 ratio in the range of 6.5 to 7.8; wherein said film having a normalized dart impact strength of equal or greater than (6666 -7012 *density) g/mil, a normalized tear strength of equal or greater than 440 * e − density − 0.915 2 2 * 0.00949 2 g / m i l, and a haze in the range of 3 to 10 percent. wherein said heterogeneously branched ethylene/α-olefin copolymer being the copolymerization reaction product of ethylene and at least one alpha-olefin comonomer in the presence of a multi-constituent catalyst system in a single reactor and optional additives, selected from the group consisting of antistatic agents, colour enhancers, dyes, lubricants, fillers, pigments, antioxidants, processing aids, stabilizers, neutralizers, blends thereof, and combinations thereof, wherein the amount of additives is less than 5 percent by weight based on the weight of the blend. heterogeneously branched ethylene/α-olefin copolymer, wherein said heterogeneously branched ethylene/α-olefin copolymer having a density in the range of 0.910 to 0.930 g/cm 3, a molecular weight distribution in the range of 2.8 to 3.8, a melt index (I 2) in the range of 0.3 to 4 g/10 min, and an I 10 /I 2 ratio in the range of 6.5 to 7.8; wherein said film having a normalized dart impact strength of equal or greater than (6666 -7012 *density) g/mil, a normalized tear strength of equal or greater than 440 * e − density − 0.915 2 2 * 0.00949 2 g / m i l, and a haze in the range of 3 to 10 percent. wherein said heterogeneously branched ethylene/α-olefin copolymer being the copolymerization reaction product of ethylene and at least one alpha-olefin comonomer in the presence of a multi-constituent catalyst system in a single reactor and optional additives, selected from the group consisting of antistatic agents, colour enhancers, dyes, lubricants, fillers, pigments, antioxidants, processing aids, stabilizers, neutralizers, blends thereof, and combinations thereof, wherein the amount of additives is less than 5 percent by weight based on the weight of the blend.
A printhead, comprising: a substrate; an first layer on the substrate; a drop generator on the substrate and comprising a nozzle in a first surface of the first layer; a programmable fuse on the substrate; a chamber in the first layer over the programmable fuse, characterised in that the chamber comprising an orifice between the chamber and the first surface of the first layer that is opposite a second surface of the first layer adjacent to the substrate; and in that it further comprises an encapsulation layer for enclosing the chamber, wherein the encapsulation layer is arranged on the first surface of the first layer so as to cover the orifice of the chamber but not to cover the nozzle. a substrate; an first layer on the substrate; a drop generator on the substrate and comprising a nozzle in a first surface of the first layer; a programmable fuse on the substrate; a chamber in the first layer over the programmable fuse, characterised in that the chamber comprising an orifice between the chamber and the first surface of the first layer that is opposite a second surface of the first layer adjacent to the substrate; and in that it further comprises an encapsulation layer for enclosing the chamber, wherein the encapsulation layer is arranged on the first surface of the first layer so as to cover the orifice of the chamber but not to cover the nozzle.
A method in a wireless LAN system, the method comprising: transmitting, in a normal mode, by a first wireless terminal (510; 1110) including a main radio module and a wake-up radio, WUR, module to a second wireless terminal (510; 1100), a WUR mode request frame to request to operate in a WUR mode including a WUR rate information element related to a transmission rate of a wake-up packet, WUP, a wherein the WUR rate information element includes a 2-bit field for one o high transmission rate of the WUP and a low transmission rate of the WUP, wherein the WUR rate information element, based on a value of the 2-bit field set to "1", includes a first setting information for the low transmission rate of the WUP, wherein the WUR rate information element, based on the value of the 2-bit field set to "2", includes a second setting information for the high transmission rate of the WUP; receiving, in the normal mode, by the first wireless terminal from the second wireless terminal, a WUR mode response frame to permit to operate in the WUR mode; and receiving, in the WUR mode, by the first wireless terminal (510; 1110) from the second wireless terminal (510; 1100), the WUP based on the WUR rate information element, wherein the WUP is modulated based on an on-off keying, OOK, scheme, and the WUP is received by the WUR module. transmitting, in a normal mode, by a first wireless terminal (510; 1110) including a main radio module and a wake-up radio, WUR, module to a second wireless terminal (510; 1100), a WUR mode request frame to request to operate in a WUR mode including a WUR rate information element related to a transmission rate of a wake-up packet, WUP, a wherein the WUR rate information element includes a 2-bit field for one o high transmission rate of the WUP and a low transmission rate of the WUP, wherein the WUR rate information element, based on a value of the 2-bit field set to "1", includes a first setting information for the low transmission rate of the WUP, wherein the WUR rate information element, based on the value of the 2-bit field set to "2", includes a second setting information for the high transmission rate of the WUP; receiving, in the normal mode, by the first wireless terminal from the second wireless terminal, a WUR mode response frame to permit to operate in the WUR mode; and receiving, in the WUR mode, by the first wireless terminal (510; 1110) from the second wireless terminal (510; 1100), the WUP based on the WUR rate information element, wherein the WUP is modulated based on an on-off keying, OOK, scheme, and the WUP is received by the WUR module.
A corner post application system for applying corner posts to a load having at least two sides that define a load corner, said corner post application system comprising: a corner post supply; a corner post applicator adapted to move a corner post from said corner post supply to the load corner; a controller adapted to rotate said corner post applicator about a vertical pivot axis until said controller determines that a retained corner post is aligned with the load corner, said controller thereafter adapted to stop rotation of said corner post applicator about said vertical pivot axis and to move said corner post linearly toward the load corner until contact is made between the corner post and the load; a sensor adapted to detect the load corner and wherein said sensor is mounted for rotational movement with said corner post applicator; characterized in that the sensor is adapted to detect the load corner by repetitively measuring a distance between said sensor and the load as said corner post applicator rotates and wherein said controller determines when a minimum value for said distance is measured. a corner post supply; a corner post applicator adapted to move a corner post from said corner post supply to the load corner; a controller adapted to rotate said corner post applicator about a vertical pivot axis until said controller determines that a retained corner post is aligned with the load corner, said controller thereafter adapted to stop rotation of said corner post applicator about said vertical pivot axis and to move said corner post linearly toward the load corner until contact is made between the corner post and the load; a sensor adapted to detect the load corner and wherein said sensor is mounted for rotational movement with said corner post applicator; characterized in that the sensor is adapted to detect the load corner by repetitively measuring a distance between said sensor and the load as said corner post applicator rotates and wherein said controller determines when a minimum value for said distance is measured.
A catheter system for recanalizing an occluded vessel comprising an antegrade longitudinal member (300, 600, 710, 800, 900, 1200) with a distal end configured to be advanced through a proximal end of an occlusion; a retrograde longitudinal member (500, 600, 720, 800, 900, 1200) with a distal end configured to be advanced through a distal end of the occlusion; and characterized in that one of either the distal end (42, 550, 970) of the antegrade longitudinal member or the distal end of the retrograde longitudinal member has a structure, comprising ribs or wires, configured to be capable of dilation to provide a plurality of openings configured to receive an opposing longitudinal member, the distal end of the at least one of the longitudinal members is further configured to be capable of contraction to close the plurality of openings to capture the distal end (975, 980) of the opposing longitudinal member to mate the antegrade and retrograde members within the occlusion and enable the mated antegrade and retrograde longitudinal members to be moved through the occlusion to form a continuous channel within the occluded vessel.
A method of decomposing an overall mask pattern into a first mask pattern and a second mask pattern comprising: decomposing an overall mask pattern including a power rail pattern (114,116) into a first mask pattern that includes a power rail base pattern (136,160) and into a second mask pattern; and generating on the second mask pattern a power rail insert pattern (138,162) that is at least partially aligned with the power rail base pattern (136,160) of the first mask pattern, wherein the power rail insert pattern (138,162) comprises at least one insert (138A,138B,162A,162B) that is arranged to overlay the power rail base pattern (136,160) and pass or reflect radiation in order to effect an exposure dose balance when fabricating a semiconductor device using the first mask pattern and the second mask pattern. decomposing an overall mask pattern including a power rail pattern (114,116) into a first mask pattern that includes a power rail base pattern (136,160) and into a second mask pattern; and generating on the second mask pattern a power rail insert pattern (138,162) that is at least partially aligned with the power rail base pattern (136,160) of the first mask pattern, wherein the power rail insert pattern (138,162) comprises at least one insert (138A,138B,162A,162B) that is arranged to overlay the power rail base pattern (136,160) and pass or reflect radiation in order to effect an exposure dose balance when fabricating a semiconductor device using the first mask pattern and the second mask pattern.
An edible ink formulation, comprising scalenohedral calcium carbonate particles, and an alcohol and an aqueous solvent, wherein the edible ink formulation, when applied as a film, exhibits a print durability score of less than 70, wherein the alcohol solvent comprises one or more C4 to C6 alcohol and one or more C2 to C3 alcohol.
A method for a User Equipment, UE, operating in a wireless communication system, the method comprising: triggering power headroom reports, PHRs, in a first Medium Access Control, MAC, entity and a second MAC entity when first type event occurs in the first MAC entity, wherein the UE is configured with the first MAC entity corresponding to a first base station and the second MAC entity corresponding to a second base station; triggering a PHR in the first MAC entity only, when a second type event occurs in the first MAC entity, wherein the first type event includes: there are uplink resources allocated for transmission on any of activated serving cells of the first MAC entity and a required power backoff due to power management for the any of activated serving cells of the first MAC entity has changed more than a threshold when a prohibitPHR-timer of the first MAC entity expires, or wherein the first type event includes: there is PUCCH, Physical Uplink Control Channel, transmission on the any of activated serving cells of the first MAC entity and a required power backoff due to power management for the any of activated serving cells of the first MAC entity has changed more than a threshold when the prohibitPHR-timer of the first MAC entity expires. triggering power headroom reports, PHRs, in a first Medium Access Control, MAC, entity and a second MAC entity when first type event occurs in the first MAC entity, wherein the UE is configured with the first MAC entity corresponding to a first base station and the second MAC entity corresponding to a second base station; triggering a PHR in the first MAC entity only, when a second type event occurs in the first MAC entity, wherein the first type event includes: there are uplink resources allocated for transmission on any of activated serving cells of the first MAC entity and a required power backoff due to power management for the any of activated serving cells of the first MAC entity has changed more than a threshold when a prohibitPHR-timer of the first MAC entity expires, or wherein the first type event includes: there is PUCCH, Physical Uplink Control Channel, transmission on the any of activated serving cells of the first MAC entity and a required power backoff due to power management for the any of activated serving cells of the first MAC entity has changed more than a threshold when the prohibitPHR-timer of the first MAC entity expires.
A projected capacitive touch system comprising: a touchscreen (110, 400); and a controller coupled to the touchscreen, the controller configured to: obtain measurements during a mixed-mode measurement frame comprising, in sequence, a self-mode measurement and a mutual-mode measurement; and based on the measurements obtained, determine a touch on the touchscreen in a presence of water contamination on the touchscreen, characterized in that the self-mode measurement comprises, in sequence within the mixed-mode measurement frame, a lower drive frequency measurement and a higher drive frequency measurement, and a higher drive frequency of the higher drive frequency measurement is at least five to ten times that of a lower drive frequency of the lower drive frequency measurement. a touchscreen (110, 400); and a controller coupled to the touchscreen, the controller configured to: obtain measurements during a mixed-mode measurement frame comprising, in sequence, a self-mode measurement and a mutual-mode measurement; and based on the measurements obtained, determine a touch on the touchscreen in a presence of water contamination on the touchscreen, obtain measurements during a mixed-mode measurement frame comprising, in sequence, a self-mode measurement and a mutual-mode measurement; and based on the measurements obtained, determine a touch on the touchscreen in a presence of water contamination on the touchscreen, characterized in that the self-mode measurement comprises, in sequence within the mixed-mode measurement frame, a lower drive frequency measurement and a higher drive frequency measurement, and a higher drive frequency of the higher drive frequency measurement is at least five to ten times that of a lower drive frequency of the lower drive frequency measurement.
Switch, especially a position switch, with a coupling for attachment of an actuating device, with the coupling having first noses for precise insertion of second noses (3, 8, 9, 10, 21) of the actuating device and a locking ring (4, 15, 16) with third noses formed on its inner circumference for locking the actuating device, characterised in that the actuating device is embodied as a drive head (1, 11, 12, 13, 20) and that a force effect arising as a result of an actuation of the drive head (1, 11, 12, 13, 20) is transmitted via the coupling by means of an arrangement and/or shapes of the first, second and/or third noses (2, 3, 5, 8, 9, 10, 21) non-positively.
A method for communicating with a plurality of nodes, comprising: requesting training signals from the nodes by sending to each node a training request message, said training request message containing a dynamically assigned unique identifier to be used by the respective node to scramble a known training sequence for generating a unique training signal; receiving the training signals from the nodes after requesting; calculate a channel state information matrix for each of the nodes from the training signals; calculating precoding matrices that define spatial streams using the channel state information matrices, wherein the precoding matrices are calculated using a plurality of the channel state information matrices; and transmitting data to the nodes on the spatial streams. requesting training signals from the nodes by sending to each node a training request message, said training request message containing a dynamically assigned unique identifier to be used by the respective node to scramble a known training sequence for generating a unique training signal; receiving the training signals from the nodes after requesting; calculate a channel state information matrix for each of the nodes from the training signals; calculating precoding matrices that define spatial streams using the channel state information matrices, wherein the precoding matrices are calculated using a plurality of the channel state information matrices; and transmitting data to the nodes on the spatial streams.