A process for preparing a multifunctional sequenced cast polyurethane matrix at room temperature, concomitantly structured in support sequence or support-barrier sequence, active substance reservoir sequence and adhesive sequence, said matrix presenting a uniqueness or a structural continuity ensured by the state of copolymerisation at the interface of the successive functional sequences, said sequences being made by phase solution constituted by mixing a liquid polyol complex of a variable composition with a liquid isocyanate, comprising the following steps: a) preparing the polyol complex 1, which consists of mixing the catalyst solution, the various additives, and, if appropriate, the active substance(s) corresponding to the function of the future sequence 1 and the polyol(s); b) preparation of the phase solution 1, which consists of mixing the polyol complex 1 obtained in step a) with the isocyanate according to the stoichiometry corresponding to the function of the future sequence 1; c) pouring of the said phase solution 1 in the mould to obtain the sequence 1 in conformity with the desired thickness of the said sequence 1; d) preparation of the polyol complex 2, which consists of mixing the catalyst solution, the various additives, and, if appropriate, the active substance(s) corresponding to the function of the future sequence 2 and the polyol(s); e) preparing of the phase solution 2, which consists of mixing the polyol complex 2 obtained in step d) with isocyanate according to the stoichiometry corresponding to the function of future sequence 2; f) pouring the phase solution 2 in the mould to obtain the sequence 2; in conformity with the desired thickness of the said sequence 2, on the sequence 1 which has exceeded a pot life, but which has still not attained the demoulding time, in order to allow a copolymerisation at the interface of the two sequences; g) repeat the steps a) to f) to obtain an "n" sequences multifunctional cast polyurethane matrix, the last and/or the first sequence according to the matrix's selected profile being a sequence at least adhesive in which the phase solution of the polyol complex with the isocyanate has a stoichiometry greater than 1; h) let the polymerisation of the last sequence terminate up to its demoulding time and therefore up to the polymerisation of the whole of the matrix; i) remove the formed multifunctional sequenced polyurethane matrix from the mould; j) package the said matrix in a sealed, tight, and impermeable pocket. a) preparing the polyol complex 1, which consists of mixing the catalyst solution, the various additives, and, if appropriate, the active substance(s) corresponding to the function of the future sequence 1 and the polyol(s); b) preparation of the phase solution 1, which consists of mixing the polyol complex 1 obtained in step a) with the isocyanate according to the stoichiometry corresponding to the function of the future sequence 1; c) pouring of the said phase solution 1 in the mould to obtain the sequence 1 in conformity with the desired thickness of the said sequence 1; d) preparation of the polyol complex 2, which consists of mixing the catalyst solution, the various additives, and, if appropriate, the active substance(s) corresponding to the function of the future sequence 2 and the polyol(s); e) preparing of the phase solution 2, which consists of mixing the polyol complex 2 obtained in step d) with isocyanate according to the stoichiometry corresponding to the function of future sequence 2; f) pouring the phase solution 2 in the mould to obtain the sequence 2; in conformity with the desired thickness of the said sequence 2, on the sequence 1 which has exceeded a pot life, but which has still not attained the demoulding time, in order to allow a copolymerisation at the interface of the two sequences; g) repeat the steps a) to f) to obtain an "n" sequences multifunctional cast polyurethane matrix, the last and/or the first sequence according to the matrix's selected profile being a sequence at least adhesive in which the phase solution of the polyol complex with the isocyanate has a stoichiometry greater than 1; h) let the polymerisation of the last sequence terminate up to its demoulding time and therefore up to the polymerisation of the whole of the matrix; i) remove the formed multifunctional sequenced polyurethane matrix from the mould; j) package the said matrix in a sealed, tight, and impermeable pocket.