mhurhangee/ep-ind-claims huggingface dataset:
A compound which is 5-(2-(4-fluoro-3-methoxy-5-methylphenylamino)-5-methylpyrimidin-4-ylamino)benzo[ d]oxazol-2 -one (Compound I) or sodium-(5-(2-(4-fluoro-3-methoxy-5-methylphenylamino)-5-methylpyrimidin-4-ylamino)-2-oxobenzo[d]oxazol-3 -yl)methyl phosphate (Compound II) for use in a method of inhibiting or treating allograft rejection in a transplant recipient, comprising: administering to the transplant recipient a first amount of a JAK1/3 inhibitor comprising Compound I or Compound II; and administering to the transplant recipient a second amount of a non-JAK1/3 immunosuppressant, wherein at least one of the first amount and the second amount is individually a suboptimal dose for inhibiting or treating allograft rejection in the transplant recipient, and wherein the combined effect of the first amount and the second amount is greater than the effect of the first amount or the second amount individually, wherein the JAK1/3 inhibitor acts in combination with the non-JAK1/3 inhibitor immunosuppressant to inhibit or treat allograft rejection. administering to the transplant recipient a first amount of a JAK1/3 inhibitor comprising Compound I or Compound II; and administering to the transplant recipient a second amount of a non-JAK1/3 immunosuppressant, wherein at least one of the first amount and the second amount is individually a suboptimal dose for inhibiting or treating allograft rejection in the transplant recipient, and wherein the combined effect of the first amount and the second amount is greater than the effect of the first amount or the second amount individually, wherein the JAK1/3 inhibitor acts in combination with the non-JAK1/3 inhibitor immunosuppressant to inhibit or treat allograft rejection.
A method comprising: obtaining, in a pre-operating system environment on a device prior to running an operating system on the device, a policy identifying configuration settings for one or more operating systems, the operating system being prevented from changing the policy; comparing, in the pre-operating system environment, the policy to configuration values used by the operating system; allowing, in the pre-operating system environment, the operating system to boot with the configuration values if the configuration values satisfy the policy; and taking, in the pre-operating system environment, a responsive action if the configuration values do not satisfy the policy; characterized in that the pre-operating system environment performs acts comprising: receiving a change to the policy; checking, whether the change to the policy is approved by an entity trusted by the pre-operating system environment; and changing the policy only if the change to the policy is approved by the entity trusted by the pre-operating system environment; wherein the change to the policy is performed only if the change is digitally signed by a policy issuer entity that is trusted by the pre-operating system environment. obtaining, in a pre-operating system environment on a device prior to running an operating system on the device, a policy identifying configuration settings for one or more operating systems, the operating system being prevented from changing the policy; comparing, in the pre-operating system environment, the policy to configuration values used by the operating system; allowing, in the pre-operating system environment, the operating system to boot with the configuration values if the configuration values satisfy the policy; and taking, in the pre-operating system environment, a responsive action if the configuration values do not satisfy the policy; characterized in that the pre-operating system environment performs acts comprising: receiving a change to the policy; checking, whether the change to the policy is approved by an entity trusted by the pre-operating system environment; and changing the policy only if the change to the policy is approved by the entity trusted by the pre-operating system environment; wherein the change to the policy is performed only if the change is digitally signed by a policy issuer entity that is trusted by the pre-operating system environment. receiving a change to the policy; checking, whether the change to the policy is approved by an entity trusted by the pre-operating system environment; and changing the policy only if the change to the policy is approved by the entity trusted by the pre-operating system environment; wherein the change to the policy is performed only if the change is digitally signed by a policy issuer entity that is trusted by the pre-operating system environment.
An HFO refrigerant composition comprising at least one type of HFO refrigerant and a polymer of halogenated propene represented by C 3 H a F b Cl c (provided that a + b + c = 6, a = an integer of 1 to 3, b = an integer of 3 to 5, and c = an integer of 0 to 1) that is an oligomer having a molecular weight of 200 to 900, wherein the oligomer content is 0.1 to 10 parts by weight per 100 parts by weight of the HFO refrigerant.
A device (200; 220) for centering an application field for an ophthalmic application at a cornea of an eye, the device comprising: a control interface adapted to receive a first parameter prior to the ophthalmic application; a imaging device adapted to capture an image of a pupil of the eye during the ophthalmic application; a determination unit adapted to determine during the ophthalmic application - a current pupil center (114; 400) and a current size of the pupil based on the image of the imaging device, - a first point by compensating a shift of the current pupil center (114; 400) using a pupil center shift characteristic representing the shift as a function of the size of the pupil, wherein the first parameter determines an extent of the compensation, and - a second point on a surface of the cornea, wherein the second point at least substantially corresponds to an apex of the corneal surface; and a control unit adapted to control the ophthalmic application by centering the application field on a centering point between the first point and the second point. a control interface adapted to receive a first parameter prior to the ophthalmic application; a imaging device adapted to capture an image of a pupil of the eye during the ophthalmic application; a determination unit adapted to determine during the ophthalmic application - a current pupil center (114; 400) and a current size of the pupil based on the image of the imaging device, - a first point by compensating a shift of the current pupil center (114; 400) using a pupil center shift characteristic representing the shift as a function of the size of the pupil, wherein the first parameter determines an extent of the compensation, and - a second point on a surface of the cornea, wherein the second point at least substantially corresponds to an apex of the corneal surface; and - a current pupil center (114; 400) and a current size of the pupil based on the image of the imaging device, - a first point by compensating a shift of the current pupil center (114; 400) using a pupil center shift characteristic representing the shift as a function of the size of the pupil, wherein the first parameter determines an extent of the compensation, and - a second point on a surface of the cornea, wherein the second point at least substantially corresponds to an apex of the corneal surface; and a control unit adapted to control the ophthalmic application by centering the application field on a centering point between the first point and the second point.
A filter comprising a substrate and a filter element mounted on the substrate, wherein the substrate is provided with a plurality of connecting line layers (14, 15, 16, 17) including a first and a second connecting line layer, the first connecting line layer being for the filter element which is formed with transmission lines and connected with the filter element, an insulating layer interposed between the first connecting line layer and the second connecting line layer, and a ground part (3, 15a) formed in at least a part of the second connecting line layer under the first connecting line layer for the filter element; wherein a thickness dimension D2 of the insulating layer interposed between the first connecting line layer for the filter element and the second connecting line layer is smaller than a width dimension D1 of each of the transmission lines formed in the first connecting line layer for the filter element or smaller than a distance between the most neighboring transmission lines among the transmission lines in the first connecting line layer for the filter element, and is larger than a thickness dimension of the second connecting line layer; and wherein at least an outermost surface insulating layer in the substrate is formed of a resin material; and at least a part of other insulating layer (12, 13) in the substrate is formed of a ceramic material.
A composition comprising a plant extract and isothiocyanate for use as a deterioration smell inhibitor or for use as an antimicrobial, wherein the plant extract is an oil-insoluble labiatae plant extract and the weight ratio of the oil-insoluble labiatae plant extract/isothiocyanate is 1/1 to 99/1.
An exhaust diffuser of a gas turbine comprising: an exhaust casing having an inner circumference wall surface; a cylindrical protection casing having an outer circumference wall surface; an annular flow path formed between the inner and outer circumference wall surfaces (10b,11b); a structure (12,13) which extends from the inner circumference wall surface to the outer circumference wall surface in a direction intersecting a main stream direction of a fluid flowing through the flow path in the mounted state in the gas turbine and in operation and which occupies a partial range of the flow path in the flow path cross section intersecting the main stream; and a concave section forming region (20,30) having an inner circumference concave section (21,31) formed in the inner circumference wall surface and an outer circumference concave section (22,32) formed in the outer circumference wall surface so as to extend throughout a range comprising the structure (12,13) in the main stream direction and so as to include a position from which the structure (12,13) extends in the flow path cross section intersecting the main stream direction such that a cross-sectional area of the flow path is varied along the main stream direction; characterized in that the inner and outer circumference concave sections (21,22,31,32), in the flow path cross section intersecting the main stream of the flow path, gradually deepen and then gradually become shallow from one side toward the other side in the circumferential direction of the flow path. an exhaust casing having an inner circumference wall surface; a cylindrical protection casing having an outer circumference wall surface; an annular flow path formed between the inner and outer circumference wall surfaces (10b,11b); a structure (12,13) which extends from the inner circumference wall surface to the outer circumference wall surface in a direction intersecting a main stream direction of a fluid flowing through the flow path in the mounted state in the gas turbine and in operation and which occupies a partial range of the flow path in the flow path cross section intersecting the main stream; and a concave section forming region (20,30) having an inner circumference concave section (21,31) formed in the inner circumference wall surface and an outer circumference concave section (22,32) formed in the outer circumference wall surface so as to extend throughout a range comprising the structure (12,13) in the main stream direction and so as to include a position from which the structure (12,13) extends in the flow path cross section intersecting the main stream direction such that a cross-sectional area of the flow path is varied along the main stream direction; characterized in that the inner and outer circumference concave sections (21,22,31,32), in the flow path cross section intersecting the main stream of the flow path, gradually deepen and then gradually become shallow from one side toward the other side in the circumferential direction of the flow path.
A controlling method for an internal combustion engine hand tool, for driving in a supporting material fastening elements under the action, upon a shot, of the firing, in a combustion chamber of the engine, of a driving fuel transferred in the chamber from a fuel cartridge by a fuel intake electric device, the device comprising a valve which, upon each shot, opens in an intake position, under the action of a current (I A) in a component created by a voltage injection control signal (U v), said method being characterized in that, upon the first one of a series of shots and after the beginning of the control signal, the time t o is detected of a drop of current during the transient rise of current and, the opening period T o of the valve being predetermined, the end of the injection control signal is triggered at the time t d, after a period T o, following the time t o, reduced with a period T OFF, of a first rise of the voltage injection control signal following the beginning of the drop of the current signal in said component or the rise, following the beginning of the drop thereof, of the current signal in said component.
A locking device for blocking a movement of a casement of a window, a French door or the like, movable against a frame, having a bolt which can be driven by a key between two positions, wherein the bolt in a closed position generates a positive locking between frame and casement and in a release position is designed for the release of the movement of the casement relative to the frame, and having an actuating shaft connected with the bolt and positive-locking surfaces (14, 15) for generating a positive locking of the key with the actuating shaft, wherein the actuating shaft has a blocking device for blocking its movement and the blocking device can be controlled by the key for cancelling the blocking of the actuating shaft, which blocking device has a blocking element displaceable by the key, the blocking element is pre-tensioned into a position blocking the movement of the actuating shaft and can be moved by the key into a position which releases the movement of the actuating shaft, characterized in that the actuating shaft is designed as a hollow shaft and that the blocking element is arranged within the actuating shaft.
A rotating wind turbine tower comprising: an external upper bearing assembly; a leading edge and a trailing edge that carry the primary tower tension and compression loads from a turbine, nacelle, and rotor thrust induced bending, the trailing edge having a maximum kinked or bowed separation from the leading edge proximate to the upper bearing assembly and tapering toward the leading edge proximate to the top and bottom tower end; a structurally efficient, progressively dimensioned hollow interior space between the leading edge and the trailing edge that produces largely constant loads in the leading edge and the trailing edge; the hollow interior space being progressively dimensioned form the top and bottom tower ends towards the mid-tower; side panels joining the leading edge and the trailing edge; a tower rotation axis passing through the center of the upper bearing assembly; a mid-tower collar surrounding the upper bearing assembly; and a plurality of guy wires, cables or rods attached to the mid-tower collar and extending to the ground. an external upper bearing assembly; a leading edge and a trailing edge that carry the primary tower tension and compression loads from a turbine, nacelle, and rotor thrust induced bending, the trailing edge having a maximum kinked or bowed separation from the leading edge proximate to the upper bearing assembly and tapering toward the leading edge proximate to the top and bottom tower end; a structurally efficient, progressively dimensioned hollow interior space between the leading edge and the trailing edge that produces largely constant loads in the leading edge and the trailing edge; the hollow interior space being progressively dimensioned form the top and bottom tower ends towards the mid-tower; side panels joining the leading edge and the trailing edge; a tower rotation axis passing through the center of the upper bearing assembly; a mid-tower collar surrounding the upper bearing assembly; and a plurality of guy wires, cables or rods attached to the mid-tower collar and extending to the ground.
Chain sling comprising a chain strand, which consists of vertical and horizontal chain links, and a connecting part which can be fastened to the said chain strand and by means of which a chain loop can be configured on the chain strand, the connecting part having two longitudinal limbs (11, 12) which are parallel to one another, configuring a gap between them, and running, in the region of their one ends, into a transverse bracket which projects from them in each case in an approximately perpendicular manner towards a front side of the connecting part, connects the two longitudinal limbs (11, 12) to one another, and configures an opening on its inner side, the gap between the two longitudinal limbs (11, 12) being wider than the stud thickness of the welded point of a chain link of the chain sling, but being smaller than the link width of a chain link of the chain strand, and a depression (18, 19) being made on the upper side of each longitudinal limb (11, 12) in the region of its inlet into the transverse bracket and on the side which faces the gap between the two longitudinal limbs (11, 12), and towards the said gap, in which depression (18, 19) an end region of a chain link which is approximately parallel to the opening plane of the gap between the two longitudinal limbs (11, 12) can be received with support at the same time in the longitudinal direction of the side limb (11, 12) in the direction towards the transverse bracket, characterized in that the longitudinal limbs (11, 12) of the connecting part can be connected to one another, in the region of their other limb ends (14, 15) which lie opposite the transverse bracket, via a pin which runs perpendicularly with respect to them and, in the assembled state, protrudes through the inner link opening of the last vertical link of the chain strand, and, in the region between the two longitudinal limbs (11, 12), the transverse bracket has a semicircularly rounded course and projects from the longitudinal limbs (11, 12) towards the front side of the connecting part to such an extent that, on its inner side, the opening extends over a length approximately half the link width of a chain link of the chain strand.
Method for the treatment of a vegetable product in the form of crushed material comprising the steps of (i) storing the crushed material in a first tank so as to let it ferment therein and form a cap of solid parts floating on a liquid mass; (ii) connecting a second tank to the first to capture therein gaseous fermentation products generated inside the first tank; (iii) connecting the second tank to the first one at a point under the cap so that, thanks to the pressure differential between the two tanks, the spontaneous transfer of gaseous products into the liquid mass occurs, so that while going up they hit the cap; characterized by mechanically pumping the gaseous products generated in the first tank into the second tank. (i) storing the crushed material in a first tank so as to let it ferment therein and form a cap of solid parts floating on a liquid mass; (ii) connecting a second tank to the first to capture therein gaseous fermentation products generated inside the first tank; (iii) connecting the second tank to the first one at a point under the cap so that, thanks to the pressure differential between the two tanks, the spontaneous transfer of gaseous products into the liquid mass occurs, so that while going up they hit the cap;
A device for protecting objects against theft and for displaying information to consumers, the protected objects being arranged at places on a display shelf, said device including: - at least one management means of the microprocessor or microcomputer type, - a detector fixed to each object, said detector allowing the detection of a theft at least by separation of the object from its detector, - a monitoring unit in connection with the management means and allowing detecting the theft, each detector being linked to the unit via a wire link through a specific port having a determined unit port reference, each of these unit port references defining a determined object place, wherein the detectors can be displaced from a wire link to another one, - information display means, each information display means corresponding to a unique unit port reference and being associated with a determined object place, each display means and each object place being hence referenced by a port reference of the unit, the detector and its object forming a pair, the detector being coded by having a unique detector identifier stored in said detector and readable by the unit, the object having hence an object identifier stored in the unit and in connection with the detector identifier, by having an intrinsic unique detector identifier stored in said detector and the device further including means for associating said object identifiers with information sources allowing the display on the information display means of a given place of said information relating to the object positioned at this place whereas the objects carrying their own detectors can be positioned at and displaced to any one of the places thanks to the detector identifiers received by the unit according to the concerned pair and allowing knowing the object through the direct link it has with its detector. - at least one management means of the microprocessor or microcomputer type, - a detector fixed to each object, said detector allowing the detection of a theft at least by separation of the object from its detector, - a monitoring unit in connection with the management means and allowing detecting the theft, each detector being linked to the unit via a wire link through a specific port having a determined unit port reference, each of these unit port references defining a determined object place, wherein the detectors can be displaced from a wire link to another one, - information display means, each information display means corresponding to a unique unit port reference and being associated with a determined object place,
A sintered valve seat having hard Co-based alloy particles dispersed in a Cu matrix; said sintered valve seat comprising by mass 2.1-6.0% of Fe and 0.8-2.2% of P, in addition to components forming said Cu matrix and said hard particles, wherein said hard particles are in an amount of 30 - 70 % by mass.