mhurhangee/ep-ind-claims huggingface dataset:
A method of detecting a presence of circulating tumor cells having a cell surface protein in a sample containing cells, said method comprising steps of: encapsulating the sample to produce one or more capsules with the sample encapsulated therein; incubating the one or more capsules with the encapsulated sample under cell culture conditions suitable for supporting cell activity and growth of said circulating tumor cells whereby the one or more incubated capsules containing said circulating tumor cells produce a first value of a pH in a range of 6.0-6.8 of a tumor microenvironment in said capsules containing said circulating tumor cells; contacting the encapsulated sample in the one or more incubated capsules with a conditionally active antibody that has a detectably higher binding affinity to the cell surface protein at the first value of the pH in the range of 6.0-6.8 of the tumor microenvironment, in comparison with the binding affinity of the conditionally active antibody to the same cell surface protein at a second value of the pH that is different from in the first value of the pH of the tumor microenvironment; and detecting the presence of said circulating tumor cells by detecting higher binding of the conditionally active antibody to the cell surface protein at the first value of the pH in the range of 6.0-6.8 of the tumor microenvironment relative to binding of the conditionally active antibody to the cell surface protein at the second value of the pH. encapsulating the sample to produce one or more capsules with the sample encapsulated therein; incubating the one or more capsules with the encapsulated sample under cell culture conditions suitable for supporting cell activity and growth of said circulating tumor cells whereby the one or more incubated capsules containing said circulating tumor cells produce a first value of a pH in a range of 6.0-6.8 of a tumor microenvironment in said capsules containing said circulating tumor cells; contacting the encapsulated sample in the one or more incubated capsules with a conditionally active antibody that has a detectably higher binding affinity to the cell surface protein at the first value of the pH in the range of 6.0-6.8 of the tumor microenvironment, in comparison with the binding affinity of the conditionally active antibody to the same cell surface protein at a second value of the pH that is different from in the first value of the pH of the tumor microenvironment; and detecting the presence of said circulating tumor cells by detecting higher binding of the conditionally active antibody to the cell surface protein at the first value of the pH in the range of 6.0-6.8 of the tumor microenvironment relative to binding of the conditionally active antibody to the cell surface protein at the second value of the pH.
An organic light emitting display device comprising: a first electrode connected to a driving transistor; an auxiliary electrode on the same layer as the first electrode; a first bank configured to cover one end of the first electrode and to cover one end of the auxiliary electrode; characterised in that: a partition wall is disposed on the first bank, the partition wall having a bottom surface comprising a first portion adjacent the first electrode and a second portion adjacent the auxiliary electrode, wherein said first portion contacts only one side of the top surface of the first bank and wherein said second portion does not contact the top surface of the first bank, such that the partition wall only partially covers the top surface of the first bank, wherein said second portion is disposed over the auxiliary electrode to be spatially spaced apart from the auxiliary electrode to have a gap therebetween. a first electrode connected to a driving transistor; an auxiliary electrode on the same layer as the first electrode; a first bank configured to cover one end of the first electrode and to cover one end of the auxiliary electrode; characterised in that: a partition wall is disposed on the first bank, the partition wall having a bottom surface comprising a first portion adjacent the first electrode and a second portion adjacent the auxiliary electrode, wherein said first portion contacts only one side of the top surface of the first bank and wherein said second portion does not contact the top surface of the first bank, such that the partition wall only partially covers the top surface of the first bank, wherein said second portion is disposed over the auxiliary electrode to be spatially spaced apart from the auxiliary electrode to have a gap therebetween.
An oligonucleotide which targets a Reprogramming factor natural antisense transcript for use as a therapeutic compound, wherein the oligonucleotide increases the expression of the Reprogramming factor, and wherein the natural antisense transcript has the nucleic acid sequence as set forth in any one of SEQ ID NOs: 4, 5 or 6, or a variant thereof which retains the function of the natural antisense transcript of SEQ ID NO: 4, 5 or 6.
Aircraft cabin module comprising: - two transverse walls extending from a longitudinal cabin wall up to a longitudinal aisle, - a longitudinal wall separating the cabin module from the aisle, - at least one service module arranged between the two transverse walls, more or less symmetrically in relation to a transverse median plane, defining with the walls of the module two contiguous personal spaces, - an access from the aisle to each personal space, - at least one seat in each personal space, each seat having at least one configuration in which it is positioned parallel to the cabin wall, - each personal space comprising elements (24, 28) capable of forming a bedding surface for at least one passenger, characterised in that at least one of the transverse walls comprises a transparent portion. - two transverse walls extending from a longitudinal cabin wall up to a longitudinal aisle, - a longitudinal wall separating the cabin module from the aisle, - at least one service module arranged between the two transverse walls, more or less symmetrically in relation to a transverse median plane, defining with the walls of the module two contiguous personal spaces, - an access from the aisle to each personal space, - at least one seat in each personal space, each seat having at least one configuration in which it is positioned parallel to the cabin wall, - each personal space comprising elements (24, 28) capable of forming a bedding surface for at least one passenger, characterised in that at least one of the transverse walls comprises a transparent portion.
A computer-implemented method for a manufacturer of a machine learning, ML, model to embed at least one marker in an electronic file to enable detection of whether the ML model has been copied or not, the method comprising: obtaining the electronic file, wherein the electronic file represents content that causes the ML model to determine an output for the electronic file according to a first processing strategy; and embedding, in the electronic file, the at least one marker that, only when detected by the ML model, causes the output of the electronic file to be determined according to a second processing strategy, the second processing strategy being unrelated to the first processing strategy and deterministically defined by the at least one marker, wherein the electronic file is a second electronic file, wherein the ML model is a second ML model, the method further comprising: providing (S102, S202) an initial electronic file as input to an initial ML model for processing, the initial ML model implementing a reverse function of the ML model, wherein content of the initial electronic file is defined by the at least one marker, and wherein an output of the initial electronic file is by the initial ML model determined according to an initial processing strategy, the output being exclusive only for electronic files comprising the at least one marker; and feeding (S104, S204) the output as input to a reverse function that generates the second electronic file as its output. obtaining the electronic file, wherein the electronic file represents content that causes the ML model to determine an output for the electronic file according to a first processing strategy; and embedding, in the electronic file, the at least one marker that, only when detected by the ML model, causes the output of the electronic file to be determined according to a second processing strategy, the second processing strategy being unrelated to the first processing strategy and deterministically defined by the at least one marker, providing (S102, S202) an initial electronic file as input to an initial ML model for processing, the initial ML model implementing a reverse function of the ML model, wherein content of the initial electronic file is defined by the at least one marker, and wherein an output of the initial electronic file is by the initial ML model determined according to an initial processing strategy, the output being exclusive only for electronic files comprising the at least one marker; and feeding (S104, S204) the output as input to a reverse function that generates the second electronic file as its output.
A pharmaceutical composition for use in a method of treating a skin blemish, the composition comprising a therapeutically effective amount of a compound having a structure: wherein each dashed line represents the presence or absence of a double bond; R 1, R 2, R 3 and R 4 are each independently selected from H and C 1 -C 6 linear alkyl; R 5 is halogen, C 1 -C 6 alkyl, or C 1 -C 6 alkenyl; R 6 is H, C 1 -C 6 alkyl, C 1 -C 6 alkenyl, a salt thereof, or an amine thereof; n is 0-7; and X is S or O. wherein each dashed line represents the presence or absence of a double bond; R 1, R 2, R 3 and R 4 are each independently selected from H and C 1 -C 6 linear alkyl; R 5 is halogen, C 1 -C 6 alkyl, or C 1 -C 6 alkenyl; R 6 is H, C 1 -C 6 alkyl, C 1 -C 6 alkenyl, a salt thereof, or an amine thereof; n is 0-7; and X is S or O.
A method for non-destructively detecting geometrical discontinuities in a translucent workpiece, which workpiece has a curved and/or polygonal surface, wherein light beams emitted from at least one light source are directed to the workpiece, wherein, to record reflected light beams, the light beams are emitted to the workpiece using a scattered light arc as the light source, which scattered light arc has a shape similar to that of the curved or polygonal surface, wherein, when the curving of the surface is concave, the scattered light arc has a similar concave shape and/or, when the curving of the surface is convex, the scattered light arc has a similar convex shape, wherein the light beams reflected at the workpiece are recorded by a hyperspectral camera, and, to record transmitted light beams, the workpiece is illuminated with monochromatic light beams and the light beams transmitted through the workpiece are recorded via an optical camera, and wherein, in a synopsis of recording methods, the results of individual methods are compared and a degree of matching is calculated. which workpiece has a curved and/or polygonal surface, wherein light beams emitted from at least one light source are directed to the workpiece, wherein, to record reflected light beams, the light beams are emitted to the workpiece using a scattered light arc as the light source, which scattered light arc has a shape similar to that of the curved or polygonal surface, wherein, when the curving of the surface is concave, the scattered light arc has a similar concave shape and/or, when the curving of the surface is convex, the scattered light arc has a similar convex shape, wherein the light beams reflected at the workpiece are recorded by a hyperspectral camera, and, to record transmitted light beams, the workpiece is illuminated with monochromatic light beams and the light beams transmitted through the workpiece are recorded via an optical camera, and wherein, in a synopsis of recording methods, the results of individual methods are compared and a degree of matching is calculated.
A precursor material for an insulation composition, comprising: a crosslinkable graft polymer comprising a polyolefin component that forms a backbone and a polyene component that forms one or more side chains grafted onto the backbone, wherein the polyene component is derived from: a) a diene comprising: i. 1,7-octadiene, 1,9-decadiene, 1,11-dodecadiene, 1,13-tetradecadiene, 7-methyl-1,6-octadiene, 9-methyl-1,8-decadiene, and/or mixture thereof; and/or ii. limonene; dicyclopentadiene, vinyl norbornene, cyclooctadiene, and/or mixtures thereof; or b) a polyene having from 3, 4, 5, 6, 7, 8, 9, 10 or more carbon-carbon double bonds and/or vinyl groups; an antioxidant; and a scorch retarder. a crosslinkable graft polymer comprising a polyolefin component that forms a backbone and a polyene component that forms one or more side chains grafted onto the backbone, wherein the polyene component is derived from: a) a diene comprising: i. 1,7-octadiene, 1,9-decadiene, 1,11-dodecadiene, 1,13-tetradecadiene, 7-methyl-1,6-octadiene, 9-methyl-1,8-decadiene, and/or mixture thereof; and/or ii. limonene; dicyclopentadiene, vinyl norbornene, cyclooctadiene, and/or mixtures thereof; or b) a polyene having from 3, 4, 5, 6, 7, 8, 9, 10 or more carbon-carbon double bonds and/or vinyl groups; a) a diene comprising: i. 1,7-octadiene, 1,9-decadiene, 1,11-dodecadiene, 1,13-tetradecadiene, 7-methyl-1,6-octadiene, 9-methyl-1,8-decadiene, and/or mixture thereof; and/or ii. limonene; dicyclopentadiene, vinyl norbornene, cyclooctadiene, and/or mixtures thereof; or i. 1,7-octadiene, 1,9-decadiene, 1,11-dodecadiene, 1,13-tetradecadiene, 7-methyl-1,6-octadiene, 9-methyl-1,8-decadiene, and/or mixture thereof; and/or ii. limonene; dicyclopentadiene, vinyl norbornene, cyclooctadiene, and/or mixtures thereof; b) a polyene having from 3, 4, 5, 6, 7, 8, 9, 10 or more carbon-carbon double bonds and/or vinyl groups; an antioxidant; and a scorch retarder.
Method for optically determining at least one analyte in a sample, in which method at least one indicator dye is used which changes at least one optical property at at least one given light wavelength ("measurement wavelength") in dependence on the concentration of a given analyte, wherein a) at least one optical property of the sample is determined at at least one measurement wavelength, b) at least one optical property of the sample is additionally determined at at least one further light wavelength ("reference wavelength"), and c) an arithmetically calculated value is ascertained from the two measured values ascertained in steps a) and b), wherein d) the value arithmetically calculated in step c) is compared to a reference curve which was ascertained on the basis of measured values ("calibration measured values") which were determined upon measurement of at least one optical property of reference samples at the at least one measurement wavelength and the at least one reference wavelength, wherein the reference samples and the sample contain at least one indicator dye and known concentrations of the analyte, e) and wherein a minimum deviation of the value arithmetically calculated in step c) from the reference curve is evaluated as an indication that the optical determination of the at least one analyte is corrupted by measurement artifacts. a) at least one optical property of the sample is determined at at least one measurement wavelength, b) at least one optical property of the sample is additionally determined at at least one further light wavelength ("reference wavelength"), and c) an arithmetically calculated value is ascertained from the two measured values ascertained in steps a) and b), d) the value arithmetically calculated in step c) is compared to a reference curve which was ascertained on the basis of measured values ("calibration measured values") which were determined upon measurement of at least one optical property of reference samples at the at least one measurement wavelength and the at least one reference wavelength, wherein the reference samples and the sample contain at least one indicator dye and known concentrations of the analyte, e) and wherein a minimum deviation of the value arithmetically calculated in step c) from the reference curve is evaluated as an indication that the optical determination of the at least one analyte is corrupted by measurement artifacts.
A method of manufacturing a foam molded article, comprising the steps of: providing a foam molding resin containing low-density polyethylene, wherein the low-density polyethylene has a melt tension of 192.5 mN, a shear viscosity of 368 Pa·s, and a melt flow rate of 1.79 g/ 10min, the melt tension being measured using a melt tension tester by extruding a strand from an orifice having a diameter of 2.095 mm and a length of 8 mm at a temperature of 190 °C and an extrusion rate of 10 mm/min, wherein the melt tension is a tension of the strand wound around a roller having a diameter of 80 mm at a speed of 16 rpm, the shear viscosity being measured at a test temperature of 190 °C at an apparent shear rate of 600/second according to JIS K-7199, the melt flow rate being measured at a test temperature of 190 °C under a test load of 2.16 kg in accordance with JIS K-7210; melt-kneading the foam molding resin and a foaming agent in a foam extruder to form a melt-kneaded resin; extruding the melt-kneaded resin, from the foam extruder, to form a foam parison; and molding the foam parison to obtain the foam molded article using a split mold, wherein the molding is selected from blow molding and vacuum molding. providing a foam molding resin containing low-density polyethylene, wherein the low-density polyethylene has a melt tension of 192.5 mN, a shear viscosity of 368 Pa·s, and a melt flow rate of 1.79 g/ 10min, the melt tension being measured using a melt tension tester by extruding a strand from an orifice having a diameter of 2.095 mm and a length of 8 mm at a temperature of 190 °C and an extrusion rate of 10 mm/min, wherein the melt tension is a tension of the strand wound around a roller having a diameter of 80 mm at a speed of 16 rpm, the shear viscosity being measured at a test temperature of 190 °C at an apparent shear rate of 600/second according to JIS K-7199, the melt flow rate being measured at a test temperature of 190 °C under a test load of 2.16 kg in accordance with JIS K-7210; melt-kneading the foam molding resin and a foaming agent in a foam extruder to form a melt-kneaded resin; extruding the melt-kneaded resin, from the foam extruder, to form a foam parison; and molding the foam parison to obtain the foam molded article using a split mold, wherein the molding is selected from blow molding and vacuum molding.
A fall prevention assembly comprising: a pole strap having a first end, a second end and a mid portion between the first end and the second end; a first connector (106, 112) having a first end slidably coupled proximate the second end of the pole strap, the first connector including a first post and a second post; a second connector coupled a select distance from the first end of the pole strap; and a lanyard having a first end, a second end and mid portion between the first and second ends, a second end of the first connector slidably coupled to the lanyard, a second end of the second connector slidably coupled to the lanyard such that the mid-portion of the pole strap and the mid-portion of the lanyard can be positioned around a pole to be climbed, characterised in that a floating back plate is engaged between a portion of the first connector and the pole strap and is configured and arranged to selectively bind the pole strap to the first connector, one side of the floating back plate including a retaining groove (111 d) for engaging the first post of the first connecting member, the spacing between the first post and the second post forming a passage through which the pole strap passes and in which the back plate is held. a pole strap having a first end, a second end and a mid portion between the first end and the second end; a first connector (106, 112) having a first end slidably coupled proximate the second end of the pole strap, the first connector including a first post and a second post; a second connector coupled a select distance from the first end of the pole strap; and a lanyard having a first end, a second end and mid portion between the first and second ends,
A releasing member-integrated transfer sheet, comprising: a releasing member comprising a first support and a melt-extruded resin layer provided on the first support, and a transfer sheet comprising a second support and a transfer layer provided on the second support, the transfer sheet being integrated with the releasing member such that the melt-extruded resin layer is opposed to the second support, wherein the transfer layer is peelable from the second support, an adhesive force between the second support and the melt-extruded resin layer is smaller than an adhesive force between the first support and the melt-extruded resin layer to thereby make the transfer sheet separable from the releasing member, an image is formed on the transfer layer by sublimation type thermal transfer, fusion type thermal transfer or inkjet printing, wherein the transfer layer is a layered structure, and a layer for forming a thermal transfer image is located on the outermost surface of the transfer layer, and the melt-extruded resin layer has a thickness of 2.5 μm or more and 50 μm or less, wherein the transfer layer has a layered structure in which a peeling layer and a receiving layer are layered in this order from the side of a second support, with the receiving layer located on the outermost surface. a releasing member comprising a first support and a melt-extruded resin layer provided on the first support, and a transfer sheet comprising a second support and a transfer layer provided on the second support, the transfer sheet being integrated with the releasing member such that the melt-extruded resin layer is opposed to the second support, wherein the transfer layer is peelable from the second support, an adhesive force between the second support and the melt-extruded resin layer is smaller than an adhesive force between the first support and the melt-extruded resin layer to thereby make the transfer sheet separable from the releasing member, an image is formed on the transfer layer by sublimation type thermal transfer, fusion type thermal transfer or inkjet printing, wherein the transfer layer is a layered structure, and a layer for forming a thermal transfer image is located on the outermost surface of the transfer layer, and the melt-extruded resin layer has a thickness of 2.5 μm or more and 50 μm or less,
An aqueous coating composition with a pigment volume concentration of from 25% to 85% comprising: i) from 5% to 60%, by weight based on the total weight of the aqueous coating composition, an aqueous copolymer dispersion comprising, in percentage by dry weight based on the dry weight of the copolymer dispersion: of (a) 90% to 99.95% of at least one ethylenically unsaturated nonionic monomer; and (b) 0.05% to 10% of at least one ethylenically unsaturated phosphorus or phosphorus salts containing monomer, copolymerized itaconic acid, or a mixture thereof; and ii) from 1% to 50%, by volume based on the total volume of the aqueous coating composition, a pigment composition comprising from 50% to 100%, by dry volume based on the total dry volume of the pigment composition, a polymer- encapsulated pigment. i) from 5% to 60%, by weight based on the total weight of the aqueous coating composition, an aqueous copolymer dispersion comprising, in percentage by dry weight based on the dry weight of the copolymer dispersion: of (a) 90% to 99.95% of at least one ethylenically unsaturated nonionic monomer; and (b) 0.05% to 10% of at least one ethylenically unsaturated phosphorus or phosphorus salts containing monomer, copolymerized itaconic acid, or a mixture thereof; and ii) from 1% to 50%, by volume based on the total volume of the aqueous coating composition, a pigment composition comprising from 50% to 100%, by dry volume based on the total dry volume of the pigment composition, a polymer- encapsulated pigment.