mhurhangee/ep-ind-claims huggingface dataset:
A microstructure apparatus comprising: a backing having a first surface and a second surface opposed thereto; a microstructure array comprising a plurality of microstructures extending outwardly from the first surface of the backing; the microstructures comprising a biodegradable distal layer and at least one proximal layer positioned between the distal layer and the first surface of the backing; the distal layer comprised of at least one therapeutic agent and at least one polymer (i) selected from (a) about 50-100% of a hydrophobic polymer and (b) a polymer with a glass transition temperature at or above about 20-25°C; or (ii) at a concentration in a polymer casting solution used to form the distal layer of the microstructures that is at or below its entanglement concentration (C E), wherein selection of the polymer is such that at least a portion of the distal layer detaches readily upon insertion of the array into skin. a backing having a first surface and a second surface opposed thereto; a microstructure array comprising a plurality of microstructures extending outwardly from the first surface of the backing; the microstructures comprising a biodegradable distal layer and at least one proximal layer positioned between the distal layer and the first surface of the backing; the distal layer comprised of at least one therapeutic agent and at least one polymer (i) selected from (a) about 50-100% of a hydrophobic polymer and (b) a polymer with a glass transition temperature at or above about 20-25°C; or (ii) at a concentration in a polymer casting solution used to form the distal layer of the microstructures that is at or below its entanglement concentration (C E), wherein selection of the polymer is such that at least a portion of the distal layer detaches readily upon insertion of the array into skin.
An ostomy appliance comprising: a hydrocolloid; and a leak detection system comprising at least one inkjet electrode arranged on the hydrocolloid, characterised in that wherein the leak detection system is configured to measure an electrical current flowing through the at least one ink jet electrode, that the leak detection system is configured to detect the ostomy leakage by measuring a change in electrical current flowing through the at least one ink jet electrode, and that the at least one inkjet electrode is configured to reduce a conductivity when exposed to an ostomy leakage. a hydrocolloid; and a leak detection system comprising at least one inkjet electrode arranged on the hydrocolloid, characterised in that wherein the leak detection system is configured to measure an electrical current flowing through the at least one ink jet electrode, that the leak detection system is configured to detect the ostomy leakage by measuring a change in electrical current flowing through the at least one ink jet electrode, and that the at least one inkjet electrode is configured to reduce a conductivity when exposed to an ostomy leakage.
Body-protector (1,1') comprising: - a wearable article (2,2'); - a shock-absorbing pad anchored to the wearable article (2,2'); wherein the shock-absorbing pad comprises a first member configured to absorb shock energy by plastic deformation and a second member configured to absorb shock energy by elastic deformation and wherein the first member is embedded in the second member; characterized in that the first member comprises a plurality of cells interconnected each other via their sidewalls to form a flexible sheet configured to absorb energy through plastic deformation of said sidewalls in response to a compressive load applied to said sheet. - a wearable article (2,2'); - a shock-absorbing pad anchored to the wearable article (2,2'); wherein the shock-absorbing pad comprises a first member configured to absorb shock energy by plastic deformation and a second member configured to absorb shock energy by elastic deformation and wherein the first member is embedded in the second member;
Safety helmet for a vehicle user, in particular for a user of a tilting vehicle, having at least one helmet body, which has an opening, having at least one visor, which is arranged outside the helmet body and in front of or on the opening of the helmet body, having at least one visor mount, which is secured on the helmet body and by means of which the visor can be secured on the helmet body in a movable manner, in particular a rotatable or pivotable manner, and can be transferred from a closed functional position, in which the opening of the helmet body is partially or at least more or less completely covered, into an open functional position, in which, in relation to the closed functional position, at least one region of the opening is accessible from the outside, and having at least one sealing unit, which comprises at least one first sealing means, which is arranged between the visor and visor mount and by means of which a gap located between the visor and visor mount can be at least more or less completely filled.
A pressure damper assembly for a fuel inlet passage in a single piston high pressure fuel pump, comprising: an inlet fitting; a cover attached to the fitting and having a substantially cylindrical sidewall defining a damping chamber adapted for fluid communication with a fuel inlet passage of the pump, and a bottom for being sealingly attached to the pump; at least one diaphragm assembly supported within the damping chamber, wherein each said diaphragm assembly includes first and second metal diaphragms (60, 61) having diaphragm rims (62, 63) sealingly secured to respective first and second sides of an imperforate central plate and convex central regions spaced from the imperforate central plate, thereby defining first and second independent closed gas volumes (25, 26) radially inward of a surrounding diaphragm assembly rim; the imperforate central plate and metal diaphragms (60, 61) are circular, and have the same radius defining the circumference of the metal diaphragms (60, 61) and imperforate plate; and the rim of each metal diaphragm (60,61) is welded to the imperforate central plate at the circumference of the metal diaphragm (60, 61); whereby feed fuel delivered to the pump through the inlet fitting flows through said damping chamber at a pressure that acts on the first and second metal diaphragms (60, 61) of each diaphragm assembly before entry into the inlet passage of the pump, characterized in that the circumference of each metal diaphragm (60, 61) is welded to the plate at the circumference of the imperforate central plate with a common weld that seals the first metal diaphragm to the imperforate central plate and the second metal diaphragm to the imperforate central plate such that the first and second independent closed gas volumes (25, 26) do not communicate; a retainer assembly supports upper and lower diaphragm assemblies within the cover, including a first retainer having a projection that bears on and biases an upper portion of the common weld; a second retainer having a projection that bears on and biases a bottom portion of the common weld on the lower diaphragm assembly; a spacer having an upper projection that bears on and biases a bottom portion of the common weld of the upper diaphragm assembly and a lower projection that bears on and biases the upper portion of the common weld of the lower diaphragm assembly; whereby the bias on the common welds maintains the diaphragm assemblies in place within the retainer assembly; and an upper portion of the cover as attached to the pump bears axially on the first retainer and the second retainer is axially immobilized by a pump housing, whereby the projections (68a, 69a) on the retainers are spring loaded against the projections (70a, 70b) of the spacer as inwardly extending portions of the projections on the retainers slide with interference along the projections of the spacer.
A biofeedback sensor attachment for a controller, the controller being a videogame controller, the biofeedback sensor attachment comprising: one or more sensors (130, 140) for obtaining biofeedback information arranged such that at least one sensor is in contact with a user's hand during normal use of the controller, wherein the sensors are arranged on one or more sleeves (110, 120) that fit at least a portion of the controller; and an output unit operable to output the biofeedback information about measurements made by the one or more sensors as an audio signal to be input to the controller. one or more sensors (130, 140) for obtaining biofeedback information arranged such that at least one sensor is in contact with a user's hand during normal use of the controller, wherein the sensors are arranged on one or more sleeves (110, 120) that fit at least a portion of the controller; and an output unit operable to output the biofeedback information about measurements made by the one or more sensors as an audio signal to be input to the controller.
Hybrid video decoder configured to predict a currently decoded frame from previously decoded video portions to obtain a prediction signal of the currently decoded frame, additionally predict a residual signal of the currently decoded frame, which relates to a prediction error of the prediction signal, by motion-compensated prediction using a reference residual signal of a previously decoded frame so as to obtain a residual prediction signal of the currently decoded frame, entropy decode a final residual signal of the currently decoded frame, and reconstruct the currently decoded frame by summing the prediction signal of the currently decoded frame, the residual prediction signal of the currently decoded frame, and the final residual signal of the currently decoded frame, wherein the hybrid video decoder is configured to entropy decode a final residual signal of the previously decoded frame, characterized in that the hybrid video decoder is configured to build a first reference residual frame of the previously decoded frame by the final residual signal of the previously decoded frame and insert same into a decoded picture buffer of the hybrid video decoder, build a second reference residual frame of the previously decoded frame by a sum of the final residual signal of the previously decoded frame and a residual prediction signal of the previously decoded frame obtained by predicting a residual signal of the previously decoded frame by motion-compensated prediction using a reference residual signal of a further previously decoded frame decoded prior to the previous decoded frame, and insert same into the decoded picture buffer, and use the first or second reference residual frame as the reference residual signal of the previously decoded frame depending on a signalization via a reference frame index within a bitstream. the prediction signal of the currently decoded frame, the residual prediction signal of the currently decoded frame, and the final residual signal of the currently decoded frame, build a first reference residual frame of the previously decoded frame by the final residual signal of the previously decoded frame and insert same into a decoded picture buffer of the hybrid video decoder, build a second reference residual frame of the previously decoded frame by a sum of the final residual signal of the previously decoded frame and a residual prediction signal of the previously decoded frame obtained by predicting a residual signal of the previously decoded frame by motion-compensated prediction using a reference residual signal of a further previously decoded frame decoded prior to the previous decoded frame, and insert same into the decoded picture buffer, and use the first or second reference residual frame as the reference residual signal of the previously decoded frame depending on a signalization via a reference frame index within a bitstream.
A passive joint device for supporting a rotation-side member rotatably about a horizontal axis in a vertical direction with respect to a fixed-side member, comprising: a cylindrical cam member having a cylindrical surface centered on the horizontal axis and fixed to the fixed-side member, the cam member having a pair of cam surfaces symmetrically arranged on the cylindrical surface about the horizontal axis and formed obliquely along the horizontal axis; a pedestal slidably disposed along the horizontal axis within the horizontal axis fixed to the rotation-side member, the pedestal having a pair of cam followers that contact with each of the pair of cam surfaces; a spring disposed inside the horizontal axis fixed to the rotation-side member, the spring biasing the pedestal toward the fixed-side member along the horizontal axis, wherein the spring force causes the pair of cam followers to come into contact with the pair of cam surfaces, push the pair of cam surfaces, and provide upward rotational force to the rotation-side member to reduce the downward rotational force of the rotation-side member by the weight applied to the rotation-side member. a cylindrical cam member having a cylindrical surface centered on the horizontal axis and fixed to the fixed-side member, the cam member having a pair of cam surfaces symmetrically arranged on the cylindrical surface about the horizontal axis and formed obliquely along the horizontal axis; a pedestal slidably disposed along the horizontal axis within the horizontal axis fixed to the rotation-side member, the pedestal having a pair of cam followers that contact with each of the pair of cam surfaces; a spring disposed inside the horizontal axis fixed to the rotation-side member, the spring biasing the pedestal toward the fixed-side member along the horizontal axis, wherein the spring force causes the pair of cam followers to come into contact with the pair of cam surfaces, push the pair of cam surfaces, and provide upward rotational force to the rotation-side member to reduce the downward rotational force of the rotation-side member by the weight applied to the rotation-side member.
An isolated metabolite of cabozantinib or a pharmaceutically acceptable salt thereof, which is a compound selected from: and wherein GA is a glucuronic acid moiety, or a pharmaceutically acceptable salt thereof.
A process for producing unilamellar liposomes by two-step emulsification method having a primary emulsification step to obtain a W1/O emulsion by emulsifying an organic solvent, an aqueous solvent and a lipid component which constitutes the lipid membrane of liposomes, a secondary emulsification step to obtain a W1/O/W2 emulsion by emulsifying the W1/O emulsion obtained by the primary emulsification step and an aqueous solvent to be an outer aqueous phase, and a solvent removal step to remove the organic solvent phase from the W1/O/W2 emulsion obtained by the secondary emulsification step, characterized by that the outer aqueous phase in the secondary emulsification step contains a dispersing agent which forms no molecular self-aggregate or a dispersing agent which exclusively forms molecular self-aggregates having a volume mean particle diameter of not more than 10 nm, wherein the dispersing agent is selected from the group consisting of protein, polysaccharides, an ionic surface active agent and a nonionic surface active agent.
A radio communication system comprising: a radio access network including first and second base stations (11, 12) configured to manage a first cell and a second cell, respectively; and a radio terminal configured to perform dual connectivity involving a bearer split in which a network bearer between the radio terminal and a core network is split over the first base station and the second base station, wherein the radio access network is configured to transmit, to the radio terminal, first control information that relates to an access stratum, wherein the first control information includes Layer-2 configuration information applied to a procedure for generating, in the radio terminal, a first Medium Access Control Protocol Data Unit, MAC PDU, for uplink transmission in the first cell and a second MAC PDU for uplink transmission in the second cell, and the system is characterized in that the Layer-2 configuration information includes information indicating that the generation of the second MAC PDU is prioritized higher than the generation of the first MAC PDU, wherein each of the first and second MAC PDU is to transmit uplink data for a logical channel of the network bearer subjected to the bearer split. a radio access network including first and second base stations (11, 12) configured to manage a first cell and a second cell, respectively; and a radio terminal configured to perform dual connectivity involving a bearer split in which a network bearer between the radio terminal and a core network is split over the first base station and the second base station, wherein the radio access network is configured to transmit, to the radio terminal, first control information that relates to an access stratum, wherein the first control information includes Layer-2 configuration information applied to a procedure for generating, in the radio terminal, a first Medium Access Control Protocol Data Unit, MAC PDU, for uplink transmission in the first cell and a second MAC PDU for uplink transmission in the second cell, and the system is characterized in that the Layer-2 configuration information includes information indicating that the generation of the second MAC PDU is prioritized higher than the generation of the first MAC PDU, wherein each of the first and second MAC PDU is to transmit uplink data for a logical channel of the network bearer subjected to the bearer split.
Method for operating a fuel operated vehicle heating device during a starting phase, said vehicle heating device comprising a burner arrangement with a combustion chamber in a combustion chamber housing, a fuel supply arrangement for supplying fuel to said combustion chamber, a combustion air supply arrangement for supplying combustion air to said combustion chamber, an electrically excitable ignition member for igniting a combustion air/fuel mixture in the area of the combustion chamber as well as a control unit for controlling said fuel supply arrangement, said combustion air supply arrangement and said ignition member, said method comprising the following measures: a) operating said fuel supply arrangement and said combustion air supply arrangement for producing a combustion air/fuel mixture in the area of said combustion chamber, b) exciting said ignition element by applying a pulsed voltage for setting a predefined target performance of said ignition member, c) when the duty cycle of the pulsed tension for said ignition member reaches a first predefined limit reducing the supply volume of said combustion air supply arrangement. a) operating said fuel supply arrangement and said combustion air supply arrangement for producing a combustion air/fuel mixture in the area of said combustion chamber, b) exciting said ignition element by applying a pulsed voltage for setting a predefined target performance of said ignition member, c) when the duty cycle of the pulsed tension for said ignition member reaches a first predefined limit reducing the supply volume of said combustion air supply arrangement.
A magnet assembly for a rotor assembly of a generator of a wind turbine, the magnet assembly comprising a magnet component comprising a permanent magnet material, a base element having a front surface being attached to the magnet component surface and a back surface for mounting the magnet assembly to a support structure of the rotor assembly, and a thermal insulation structure covering at least a part of a surface of the magnet component for thermally decoupling the magnet component from heat being generated within the generator, wherein the thermal insulation structure comprises a thermal insulating material and an enclosure structure (476,576) surrounding at least the magnet component characterized in that the enclosure structure (476,576) spatially separates the magnet component from the thermal insulating material.
A coated glass article comprising: a glass container comprising a first surface and a second surface opposite the first surface; and a low-friction coating bonded to at least a portion of the first surface of the glass container, the low-friction coating comprising a polyimide chemical composition, wherein the polyimide chemical composition is halogenated and wherein the polyimide chemical composition comprises a siloxane moiety. a glass container comprising a first surface and a second surface opposite the first surface; and a low-friction coating bonded to at least a portion of the first surface of the glass container, the low-friction coating comprising a polyimide chemical composition, wherein the polyimide chemical composition is halogenated and wherein the polyimide chemical composition comprises a siloxane moiety.
Turbine engine for aircraft, including a shaft of a turbine engine and a pumping module comprising: - a structural housing in which are arranged a suction flange, in order to draw off fuel from a tank, and a delivery flange, - a pump shaft connected to the shaft of the turbine engine, - a pump for supplying fuel to the turbine engine, mounted on said pump shaft and mounted inside the structural housing, adapted in order to deliver a flow of fuel as a function of the speed of rotation of the shaft of the turbine engine, the supply pump including a first fixed central part, joined to the structural housing, comprising a hollow delivery shaft connected to the delivery flange and a movable part mounted outside the fixed central part thereof, - an electrical device which is mounted on said pump shaft and is adapted, according to a first mode of operation, to drive said pump shaft in rotation in order to actuate the supply pump and, according to a second mode of operation, to be driven in rotation by said pump shaft in order to supply electrical power to an equipment of the turbine engine, the electrical device including rotor elements mounted on the external periphery of the movable part of the supply pump and stator elements mounted on the internal periphery of a fixed external crown of the structural housing and - coupling/decoupling means adapted in order to decouple the shaft of the turbine engine and the pump shaft according to the first mode of operation and in order to couple them according to the second mode of operation. - a structural housing in which are arranged a suction flange, in order to draw off fuel from a tank, and a delivery flange, - a pump shaft connected to the shaft of the turbine engine, - a pump for supplying fuel to the turbine engine, mounted on said pump shaft and mounted inside the structural housing, adapted in order to deliver a flow of fuel as a function of the speed of rotation of the shaft of the turbine engine, the supply pump including a first fixed central part, joined to the structural housing, comprising a hollow delivery shaft connected to the delivery flange and a movable part mounted outside the fixed central part thereof, - an electrical device which is mounted on said pump shaft and is adapted, according to a first mode of operation, to drive said pump shaft in rotation in order to actuate the supply pump and, according to a second mode of operation, to be driven in rotation by said pump shaft in order to supply electrical power to an equipment of the turbine engine, the electrical device including rotor elements mounted on the external periphery of the movable part of the supply pump and stator elements mounted on the internal periphery of a fixed external crown of the structural housing and - coupling/decoupling means adapted in order to decouple the shaft of the turbine engine and the pump shaft according to the first mode of operation and in order to couple them according to the second mode of operation.