A vehicle drive route instruction system in a hybrid vehicle driven by only an electric motor or driven by both an electric motor and an internal combustion engine, said vehicle drive route instruction system comprising: an SOC amount acquiring unit acquiring an SOC amount of a battery which is a source of supply of electric power to the electric motor, a vehicle position detecting unit detecting a current position of the vehicle, a zone judging unit judging if currently the vehicle is driving through an inside of an engine drive restriction zone where driving by the internal combustion engine is restricted, an operation control unit making the internal combustion engine stop operating and making the electric motor drive the vehicle when it is judged that currently the vehicle is driving through the engine drive restriction zone, the system being characterized by further comprising: a shortest route searching unit searching for a shortest route from the current position to a boundary of an inside of the engine drive restriction zone and an outside of the engine drive restriction zone when it is judged that currently the vehicle is driving through the inside of the engine drive restriction zone, a decreased SOC amount calculating unit calculating a decreased SOC amount when driving the vehicle through the searched shortest route from the current position to the boundary, an SOC amount judging unit judging if the SOC amount will fall to a preset judgment standard based on the current SOC amount and the calculated decreased SOC amount when driving the vehicle through the searched shortest route from the current position to the boundary based, and a guidance device giving information to an occupant of the vehicle to guide the vehicle from the current position through the searched shortest route to the boundary in case where it is judged that the SOC amount will fall to the judgment standard when driving the vehicle through the searched shortest route from the current position to the boundary. an SOC amount acquiring unit acquiring an SOC amount of a battery which is a source of supply of electric power to the electric motor, a vehicle position detecting unit detecting a current position of the vehicle, a zone judging unit judging if currently the vehicle is driving through an inside of an engine drive restriction zone where driving by the internal combustion engine is restricted, an operation control unit making the internal combustion engine stop operating and making the electric motor drive the vehicle when it is judged that currently the vehicle is driving through the engine drive restriction zone, a shortest route searching unit searching for a shortest route from the current position to a boundary of an inside of the engine drive restriction zone and an outside of the engine drive restriction zone when it is judged that currently the vehicle is driving through the inside of the engine drive restriction zone, a decreased SOC amount calculating unit calculating a decreased SOC amount when driving the vehicle through the searched shortest route from the current position to the boundary, an SOC amount judging unit judging if the SOC amount will fall to a preset judgment standard based on the current SOC amount and the calculated decreased SOC amount when driving the vehicle through the searched shortest route from the current position to the boundary based, and a guidance device giving information to an occupant of the vehicle to guide the vehicle from the current position through the searched shortest route to the boundary in case where it is judged that the SOC amount will fall to the judgment standard when driving the vehicle through the searched shortest route from the current position to the boundary.