mhurhangee/ep-ind-claims huggingface dataset:
A method of using ultrasonic radiation for controlled fragmentation of a genetic sample that includes chains of nucleic acids, the method comprising: providing a transducer that includes a substrate with top and bottom electrodes (106,108) configured as a Fresnel Annular Sector Actuator (FASA) that directs acoustic energy in a target direction; providing a sample container to contain the genetic sample, the sample container being disposed in the target direction of the transducer, and the sample container being acoustically coupled to the transducer through a coupling medium; and applying an input waveform to the transducer to direct acoustic energy to the genetic sample over a specified time interval, the genetic sample being reduced to fragments of nucleic acid having an average fragment size that corresponds to the specified time interval, wherein the input waveform comprises tone bursts having a selected repetition rate and duty cycle. providing a transducer that includes a substrate with top and bottom electrodes (106,108) configured as a Fresnel Annular Sector Actuator (FASA) that directs acoustic energy in a target direction; providing a sample container to contain the genetic sample, the sample container being disposed in the target direction of the transducer, and the sample container being acoustically coupled to the transducer through a coupling medium; and applying an input waveform to the transducer to direct acoustic energy to the genetic sample over a specified time interval, the genetic sample being reduced to fragments of nucleic acid having an average fragment size that corresponds to the specified time interval, wherein the input waveform comprises tone bursts having a selected repetition rate and duty cycle.
A combination of (a) a histone deacetylase inhibitor (HDAI) and (b) an anti-metabolite, wherein (a) is N -hydroxy-3-[4-[[[2-(2-methyl-1 H -indol-3-yl)-ethyl]-amino]methyl]phenyl]-2 E -2-propenamide, or a pharmaceutically acceptable salt thereof, and (b) is 5-azacitidine for use in the treatment of a proliferative disease which is myelodysplastic syndrome or acute myeloblastic leukemia.
An electric-vehicle fault detection system comprising a first electric-vehicle controller and a second electric-vehicle controller: the first electric-vehicle controller being configured to send a control signal to the second electric-vehicle controller and to send a second signal to the second electric-vehicle controller, and the second electric-vehicle controller being configured to receive the control signal and the second signal from the first electric-vehicle controller; compare information from the signals in order to determine a deviation between the signals; and determine whether there is a vehicle fault based on the determined deviation between the signals, characterised in that the control signal is not a pulse width modulated signal and the second signal is a pulse width modulated signal comprising the same information as the control signal. the first electric-vehicle controller being configured to send a control signal to the second electric-vehicle controller and to send a second signal to the second electric-vehicle controller, and the second electric-vehicle controller being configured to receive the control signal and the second signal from the first electric-vehicle controller; compare information from the signals in order to determine a deviation between the signals; and determine whether there is a vehicle fault based on the determined deviation between the signals, characterised in that the control signal is not a pulse width modulated signal and the second signal is a pulse width modulated signal comprising the same information as the control signal.
A blade outer air seal assembly, comprising: a blade outer air seal segment comprising a forward rail and an aft rail; a blade outer air seal support coupled to the blade outer air seal segment, the blade outer air seal support comprising an aft flange, a first forward flange and a second forward flange, the second forward flange being located forward of the first forward flange, wherein the forward rail is located between the first forward flange and the second forward flange; and a pin disposed through the aft rail, the aft flange, the first forward flange, and the forward rail, characterised in that the first forward flange, the second forward flange and the forward rail are each castellated, and wherein a proximal surface of the forward rail is axially aligned with a distal surface of the first forward flange and with a distal surface of the second forward flange. a blade outer air seal segment comprising a forward rail and an aft rail; a blade outer air seal support coupled to the blade outer air seal segment, the blade outer air seal support comprising an aft flange, a first forward flange and a second forward flange, the second forward flange being located forward of the first forward flange, wherein the forward rail is located between the first forward flange and the second forward flange; and a pin disposed through the aft rail, the aft flange, the first forward flange, and the forward rail, characterised in that the first forward flange, the second forward flange and the forward rail are each castellated, and wherein a proximal surface of the forward rail is axially aligned with a distal surface of the first forward flange and with a distal surface of the second forward flange.
A method for receiving broadcast signals modulated using Quadrature Amplitude Modulation / Orthogonal Frequency Division Multiplexing, QAM/OFDM, with an M-QAM constellation and an N-QAM constellation, the method comprising; receiving first and second broadcast signals through first and second antennas and demodulating the first and second broadcast signals by an OFDM method; time de-interleaving symbol data in the demodulated first and second broadcast signals; and, Multi-input Multi-Output, MIMO, processing the time de-interleaved symbol data into first and second output signals including probability information of bits, wherein the MIMO processing is performed by using a MIMO processing matrix represented as 1 1 + a 2 ⁢ 1 a a - 1 = 1 1 + a 2 a 1 + a 2 a 1 + a 2 - 1 1 + a 2 = cos θ sin θ sin θ - cos θ, wherein a = 2 + 4 2 + 2 for M = N = 16; merging the first and second output signals of the MIMO processing to generate a single stream; and Forward Error Correction, FEC, decoding the generated single stream to output Physical Layer Pipe, PLP, data. receiving first and second broadcast signals through first and second antennas and demodulating the first and second broadcast signals by an OFDM method; time de-interleaving symbol data in the demodulated first and second broadcast signals; and, Multi-input Multi-Output, MIMO, processing the time de-interleaved symbol data into first and second output signals including probability information of bits, wherein the MIMO processing is performed by using a MIMO processing matrix represented as 1 1 + a 2 ⁢ 1 a a - 1 = 1 1 + a 2 a 1 + a 2 a 1 + a 2 - 1 1 + a 2 = cos θ sin θ sin θ - cos θ, wherein a = 2 + 4 2 + 2 for M = N = 16; merging the first and second output signals of the MIMO processing to generate a single stream; and Forward Error Correction, FEC, decoding the generated single stream to output Physical Layer Pipe, PLP, data.
A method of determining spatial division of an environment, the method comprising: determining a movement footprint of a user walking along a wall in the environment at least in part based on a communication between a first communication device and a second communication device, the first communication device being carried by the user, and the second communication device being placed in the environment; generating a representation of the spatial division of the environment based on the determined movement footprint; determining an estimated size associated with at least one reference object in the environment according to the representation of the spatial division; obtaining a reference size associated with the at least one reference object; and adjusting the representation of the spatial division based on a comparison of the estimated size and the reference size.
A consumer product (100, 200, 300, 400, 500, 600, 700, 800, 900, 1000, 1100) comprising a detergent product and a container, the container comprising a box (101, 201, 301, 401, 501, 601, 701, 801, 901, 1001, 1101), a cover (102, 202, 302, 402, 502, 602, 702, 802, 902, 1002, 1102) for the box, and a lock (103, 203, 303, 403, 503, 603, 703, 803, 903, 1003, 1103) to reversibly maintain the cover in a closed position, the box comprising a detergent product, the box comprising a base (104, 204, 304, 404, 504, 604, 704, 804, 904, 1004, 1104), sidewalls (105, 205, 305, 405, 505, 605, 705, 805, 905, 1005, 1105) and an opening (112, 212, 312, 412, 512, 612, 712, 812, 912, 1012, 1112), the cover comprising a top (106, 206, 306, 406, 506, 606, 706, 806, 906, 1006, 1116) and flanks (107, 207, 307, 407, 507, 607, 707, 807, 907, 1007, 1107), the cover covering the opening and the cover covering at least a specific portion of a specific sidewall of the box when the cover is in the closed position, the lock comprising an actuator moveable from a locking position to an opening position by applying an actuation pressure onto the actuator when the cover is in the closed position, the actuator being connected to the specific portion, the flanks comprising an actuation area (311, 411) the actuation area facing the actuator and permitting displacing the actuator from the closing position to the opening position by applying the actuation pressure at the actuation area when the cover is in the closed position, the actuator being moveable from the opening position to the closing position by the actuator releasing an elastic force, the release of the elastic force occurring when the cover is placed in a specific releasing position, characterized in that at least one of the flanks and sidewalls comprises an alignment mark (110, 210, 310, 410, 510, 610, 710, 810, 910, 1010, 1110) coinciding with the cover being in the closed position passed the specific releasing position.
A fire extinguisher vessel comprising: a hollow body made of stainless steel; a fill port attached to a first end of the body; a discharge outlet attached to a second end of the body; a mechanical attachment lug attached to the body between the first end of the body and the second end of the body; a pressure switch attached to the body between the mechanical attachment lug and the discharge outlet; and a retrofitted wrap covering the body, wherein the wrap comprises high strength fiberglass and has a thickness between about 0.0159 centimeters and about 0.3175 centimeters (0.0625 inch and about 0.125 inch); wherein the wrap increases an agent fill density of the fire extinguishing vessel to at least about 0.00072 kilograms per cubic centimeter (0.026 pounds per cubic inch); and wherein the wrap completely surrounds bases of the fill port, the discharge outlet, the mechanical attachment lug, and the pressure switch. a hollow body made of stainless steel; a fill port attached to a first end of the body; a discharge outlet attached to a second end of the body; a mechanical attachment lug attached to the body between the first end of the body and the second end of the body; a pressure switch attached to the body between the mechanical attachment lug and the discharge outlet; and a retrofitted wrap covering the body, wherein the wrap comprises high strength fiberglass and has a thickness between about 0.0159 centimeters and about 0.3175 centimeters (0.0625 inch and about 0.125 inch); wherein the wrap increases an agent fill density of the fire extinguishing vessel to at least about 0.00072 kilograms per cubic centimeter (0.026 pounds per cubic inch); and wherein the wrap completely surrounds bases of the fill port, the discharge outlet, the mechanical attachment lug, and the pressure switch.
A method of controlling a variable area gas turbine engine, comprising: running the variable area turbine engine at initial settings; monitoring two sets (2102A, 2102B) of operating parameters of the engine at the initial settings; and deducing vane angles (2103A, 2103B) of adjustable vanes without directly measuring the vane angles from mapped data of the two sets (2102A, 2102B) of operating parameters of a similar engine operated while direct vane angle measurements were being recorded. running the variable area turbine engine at initial settings; monitoring two sets (2102A, 2102B) of operating parameters of the engine at the initial settings; and deducing vane angles (2103A, 2103B) of adjustable vanes without directly measuring the vane angles from mapped data of the two sets (2102A, 2102B) of operating parameters of a similar engine operated while direct vane angle measurements were being recorded.
A computer-implemented method comprising: receiving a set of data from a battery, the set of data comprising battery voltage (V i) and current (I i) data obtained over a period of time (t i); preparing a plurality of subsets of the set of data, wherein each subset corresponds to a subperiod of the period of time; determining a state of health of the battery versus time by fitting a battery model to the subsets, wherein the parameters of the battery model comprise: a state of charge of the battery at a particular point of time in each subperiod; and the state of health, characterized in that: the time dependence of the state of health is controlled thereby limiting the magnitude of the temporal rate of change of the state of health; and in that the method further comprises providing an alert in response to the state of health meeting a particular criterion, wherein the method further comprises determining a set of parameters describing the state of health as a function of time using a particular number of the initial subsets; and then updating the parameters using at least one further subset. receiving a set of data from a battery, the set of data comprising battery voltage (V i) and current (I i) data obtained over a period of time (t i); preparing a plurality of subsets of the set of data, wherein each subset corresponds to a subperiod of the period of time; determining a state of health of the battery versus time by fitting a battery model to the subsets, wherein the parameters of the battery model comprise: a state of charge of the battery at a particular point of time in each subperiod; and the state of health, characterized in that: the time dependence of the state of health is controlled thereby limiting the magnitude of the temporal rate of change of the state of health; and in that the method further comprises providing an alert in response to the state of health meeting a particular criterion, wherein the method further comprises determining a set of parameters describing the state of health as a function of time using a particular number of the initial subsets; and then updating the parameters using at least one further subset. a state of charge of the battery at a particular point of time in each subperiod; and the state of health, characterized in that: the time dependence of the state of health is controlled thereby limiting the magnitude of the temporal rate of change of the state of health; and in that the method further comprises providing an alert in response to the state of health meeting a particular criterion, wherein the method further comprises determining a set of parameters describing the state of health as a function of time using a particular number of the initial subsets; and then updating the parameters using at least one further subset.
A composition for use in treating Duchenne Muscular Dystrophy associated with a reading frame shift in a dystrophin gene in a subject in need thereof, the composition comprising (i) a first nuclease that cuts a first recognition sequence or RNA or DNA encoding said first nuclease; and (ii) a second nuclease that cuts a second recognition sequence or RNA or DNA encoding said second nuclease; wherein said first recognition sequence is upstream of a first exon in the dystrophin gene of a muscle cell of said subject; wherein said second recognition sequence is downstream of said first exon in the dystrophin gene of a muscle cell of said subject; wherein said first recognition sequence and said second recognition sequence have complementary overhangs when cut by said first nuclease and said second nuclease; and wherein said first nuclease and said second nuclease are capable of removing at least one further exon from said dystrophin gene in said muscle cell such that the normal reading frame of said dystrophin gene is restored. (i) a first nuclease that cuts a first recognition sequence or RNA or DNA encoding said first nuclease; and (ii) a second nuclease that cuts a second recognition sequence or RNA or DNA encoding said second nuclease; wherein said first recognition sequence is upstream of a first exon in the dystrophin gene of a muscle cell of said subject; wherein said second recognition sequence is downstream of said first exon in the dystrophin gene of a muscle cell of said subject; wherein said first recognition sequence and said second recognition sequence have complementary overhangs when cut by said first nuclease and said second nuclease; and wherein said first nuclease and said second nuclease are capable of removing at least one further exon from said dystrophin gene in said muscle cell such that the normal reading frame of said dystrophin gene is restored.
A method for using a local media playback system comprising a plurality of playback zones (610, 620; 906) having a plurality of playback functions, the method comprising: in response to an instruction from a first controller (300; 500; 630-633) of a first user to cause the local media playback system to enter a party playlist mode, the first user being authenticated to enter the party playlist mode, causing the local media playback system to enter the party playlist mode, wherein, in the party playlist mode: a second user is provided with limited access to control one or more playback zones via a second controller, the limited access being applied based on authentication of the second user, the one or more playback zones corresponding to a limited subset of the plurality of playback zones of the local media playback system; and while the local media playback system is in the party playlist mode, and responsive to an input from the second user, causing a media item to be added to a playlist for playback by a particular playback zone of the limited subset. in response to an instruction from a first controller (300; 500; 630-633) of a first user to cause the local media playback system to enter a party playlist mode, the first user being authenticated to enter the party playlist mode, causing the local media playback system to enter the party playlist mode, wherein, in the party playlist mode: a second user is provided with limited access to control one or more playback zones via a second controller, the limited access being applied based on authentication of the second user, the one or more playback zones corresponding to a limited subset of the plurality of playback zones of the local media playback system; and while the local media playback system is in the party playlist mode, and responsive to an input from the second user, causing a media item to be added to a playlist for playback by a particular playback zone of the limited subset.
Method of treatment of an organic waste material in a liquid form comprising: - subjecting the liquid waste material to a first solid/liquid separation step resulting in a clarified fraction and a concentrated fraction; - subjecting said concentrated fraction to anaerobic fermentation in a biogas reactor resulting in a first digestate; - subjecting said first digestate and said clarified fraction to an anaerobic fermentation in a UASB reactor resulting in a second digestate; and - subjecting said second digestate to ultrafiltration and reverse osmosis. - subjecting the liquid waste material to a first solid/liquid separation step resulting in a clarified fraction and a concentrated fraction; - subjecting said concentrated fraction to anaerobic fermentation in a biogas reactor resulting in a first digestate; - subjecting said first digestate and said clarified fraction to an anaerobic fermentation in a UASB reactor resulting in a second digestate; and - subjecting said second digestate to ultrafiltration and reverse osmosis.
A distance measurement system comprising an optical arrangement and a dual sweep frequency scanning interferometry system, the optical arrangement including: a frequency swept laser; a fixed frequency pump laser source; a first input to receive a first beam from the frequency swept laser; a second input to receive a second beam from the fixed frequency pump laser source; a non-linear optical artefact to receive, and to intermodulate, the first and second beams to generate a third beam, the third beam being an inverted copy of the first beam mirrored relative to the fixed frequency of the pump laser source; a filter to extract the third beam from the output of the non-linear optical artefact; and, a combining element to combine and output the first beam and the filtered third beam to the frequency scanning interferometry system (200, 300), wherein the non-linear artefact is selected or configured such that the optical frequency separation of the first and second beams satisfies the coherence length condition of the non-linear artefact and induces four wave mixing in the non-linear optical artefact to generate the third beam when the first and second beams are intermodulated, the dual sweep frequency scanning interferometry system (200, 300) including an interferometer and is arranged to direct the combined first and third beams through the interferometer to illuminate a target point, to receive a reflected signal, and to determine the distance to the target point therefrom. a frequency swept laser; a fixed frequency pump laser source; a first input to receive a first beam from the frequency swept laser; a second input to receive a second beam from the fixed frequency pump laser source; a non-linear optical artefact to receive, and to intermodulate, the first and second beams to generate a third beam, the third beam being an inverted copy of the first beam mirrored relative to the fixed frequency of the pump laser source; a filter to extract the third beam from the output of the non-linear optical artefact; and, a combining element to combine and output the first beam and the filtered third beam to the frequency scanning interferometry system (200, 300), wherein the non-linear artefact is selected or configured such that the optical frequency separation of the first and second beams satisfies the coherence length condition of the non-linear artefact and induces four wave mixing in the non-linear optical artefact to generate the third beam when the first and second beams are intermodulated, the dual sweep frequency scanning interferometry system (200, 300) including an interferometer and is arranged to direct the combined first and third beams through the interferometer to illuminate a target point, to receive a reflected signal, and to determine the distance to the target point therefrom.