A thrombus extraction device configured to remove thrombus along a guide wire, the thrombus extraction device comprising: a thrombus suction assembly comprising an outer tube, a transmission tube, a driving member, and a thrombus suction head, wherein the outer tube is sleeved outside the transmission tube, one end of the outer tube is connected to the thrombus suction head, the thrombus suction head is provided with a thrombus smashing cutter therein, the thrombus suction head is configured to suck in and smash the thrombus, both ends of the transmission tube are connected to the thrombus smashing cutter and the driving member, respectively, the driving member is configured to drive the transmission tube to rotate; and, a thrombus extraction assembly configured to draw the thrombus to the thrombus suction head, the thrombus extraction assembly comprising a multi-lumen tube and a balloon provided at one end of the multi-lumen tube, wherein the balloon has a deflated state and a liquid filled inflated state, the multi-lumen tube is provided with a liquid filling cavity therein configured to fill the balloon with liquid and a guide wire cavity therein configured to allow the guide wire to extend through, the multi-lumen tube extends through the transmission tube and the thrombus suction head sequentially, such that the thrombus extraction assembly is movable with respect to the thrombus suction assembly in an axial direction; wherein the thrombus suction head is of a hollow structure, the thrombus smashing cutter is provided in the thrombus suction head and is sleeved outside the multi-lumen tube, an end surface of the thrombus suction head is provided with a thrombus pulling hole configured to allow the multi-lumen tube to extend through and at least one thrombus extraction hole configured to suck in the thrombus, an end surface of the thrombus smashing cutter is provided with a blade, and the thrombus extraction hole faces the blade. a thrombus suction assembly comprising an outer tube, a transmission tube, a driving member, and a thrombus suction head, wherein the outer tube is sleeved outside the transmission tube, one end of the outer tube is connected to the thrombus suction head, the thrombus suction head is provided with a thrombus smashing cutter therein, the thrombus suction head is configured to suck in and smash the thrombus, both ends of the transmission tube are connected to the thrombus smashing cutter and the driving member, respectively, the driving member is configured to drive the transmission tube to rotate; and, a thrombus extraction assembly configured to draw the thrombus to the thrombus suction head, the thrombus extraction assembly comprising a multi-lumen tube and a balloon provided at one end of the multi-lumen tube, wherein the balloon has a deflated state and a liquid filled inflated state, the multi-lumen tube is provided with a liquid filling cavity therein configured to fill the balloon with liquid and a guide wire cavity therein configured to allow the guide wire to extend through, the multi-lumen tube extends through the transmission tube and the thrombus suction head sequentially, such that the thrombus extraction assembly is movable with respect to the thrombus suction assembly in an axial direction; wherein the thrombus suction head is of a hollow structure, the thrombus smashing cutter is provided in the thrombus suction head and is sleeved outside the multi-lumen tube, an end surface of the thrombus suction head is provided with a thrombus pulling hole configured to allow the multi-lumen tube to extend through and at least one thrombus extraction hole configured to suck in the thrombus, an end surface of the thrombus smashing cutter is provided with a blade, and the thrombus extraction hole faces the blade.