Hello how may I help you? hi there when does the subway run in downtown New York City between East and 5th Street? The subway start again at 6 a.m. great! Anything else? do you know how long if departing the subway from East and 5th to get to Downtown? 35 minutes thanks Anything else? What about, do you know if I miss the first one how long I have to wait for the next? They come along every hour