Hello how may I help you? what river runs through prague he Vltava River flows through the centre of Prague, and is the waterway around which the city has developed over the past 1000 years. is the water clean Unfortunately there is currently a lot of waste in the river. what kind of waste Waste from the sewer system has flowed into the river. can you swim in it It may be safe to swim in for a short amount of time. gross Is there anything else you need help with today?