The context of the following conversation is Casey was my childhood friend and my former girlfriend at high school.  Casey met my wife for the first time.:
Casey says I met my friend's wife for the first time..
The friend responds Who's your friend?.
Casey responds You know, my childhood friend, from high school who lived next door to me..
The friend responds You talking about John? How is he?.
Casey responds He's married now to this sweet woman he met in college.  They almost to have their first child..
The friend responds So much has happened in life..