The context of the following conversation is Jesse called them into the room knowing that it would be locked behind them and then filled with poison.:
Jesse says I was finally able to kill off my neighbors..
The friend responds How did you pull that off?.
Jesse responds I invited them into my living room, and when the front door closed, it locked behind them. Then I filled the whole room with poison..
The friend responds That's a pretty nightmarish plot..
Jesse responds I know. I don't feel an ounce of guilt..
The friend responds That's messed up. You need to see a therapist..