mdpi-ai/citelens huggingface dataset:
Homework’s Implications for the Well-Being of Primary School Pupils—Perceptions of Children, Parents, and Teachers
Field: EDUCATION

Teachers and educational researchers explore various approaches to make homework more engaging and enjoyable, intending to improve the well-being and academic performance of primary school students. The study aimed to identify practices with positive and negative effects on students’ well-being when doing homework. The views of those involved in giving, doing, and assessing homework were captured from three perspectives, namely, teachers, students, and parents. In May–June 2022, six online focus groups were conducted with the participation of 13 teachers, 11 parents, and 16 primary school students from a Romanian school. The thematic analysis identified the homework that the children (do not) like; their reactions when they receive, do, and are assessed for such homework; and suggestions on how to improve the homework. The results revealed that homework assignments that make young schoolchildren feel capable, effective, appreciated, and rewarded; homework done in teams in the form of competitions or games; parental involvement in collaborative homework; and homework with creative elements are effective ways that contribute to the well-being of primary school pupils when doing homework. Repetitive, lengthy, tedious, overloaded homework generates frustration, discouragement, and emotional reactions such as crying, abandonment, anxiety, and sleep deprivation.
Transdiagnostic phenomena of psychopathology in the context of the RDoC: protocol of a multimodal cross-sectional study
Field: PSYCHOLOGY

In the past, affective and cognitive processes related to psychopathology have been examined within the boundaries of phenotype-based diagnostic labels, which has led to inconsistent findings regarding their underlying operating principles. Investigating these processes dimensionally in healthy individuals and by means of multiple modalities may provide additional insights into the psychological and neuronal mechanisms at their core. The transdiagnostic phenomena Neuroticism and Rumination are known to be closely linked. However, the exact nature of their relationship remains to be elucidated. The same applies to the associations between Hedonic Capacity, Negativity Bias and different Emotion Regulation strategies. This multimodal cross-sectional study examines the relationship of the transdiagnostic phenomena Neuroticism and Rumination as well as Hedonic Capacity, the Negativity Bias and Emotion Regulation from a RDoC (Research Domain Criteria) perspective. A total of 120 currently healthy subjects (past 12 months) will complete several questionnaires regarding personality, emotion regulation, hedonic capacity, and psychopathologies as well as functional magnetic resonance imaging (fMRI) during cognitive and emotional processing, to obtain data on the circuit, behavioral and self-report level. This study aims to contribute to the understanding of the relationship between cognitive and affective processes associated with psychopathologies as well as their neuronal correlates. Ultimately, a grounded understanding of these processes could guide improvement of diagnostic labels and treatments. Limitations include the cross-sectional design and the limited variability in psychopathology scores due to the restriction of the sample to currently healthy subjects.
A Qualitative Study to Explore the Life Experiences of Older Adults in Oman
Field: PSYCHOLOGY

Background: Reminiscence studies and life reviews have a number of proven advantages. Future generations gain by learning from elders’ life experiences, as do older adults themselves who share their memories. Despite Oman’s sizable geriatric population, research on older individuals’ life experiences is scarce. Therefore, this study aimed to explore the life experiences of older Omani individuals across their many life stages, from childhood to the present. Methods: This was a qualitative study design. Convenience sampling was employed and conducted from December 2021 to October 2022. A total of 13 Omani older adults (9 females and 4 males), with an average age of 68 years, were recruited for this study (response rate = 34%). Socio-demographic and life review information was gathered according to a set of semi-structured guiding questions. The responses were then captured on audio recordings, which underwent transcription and translation. Thematic analysis techniques were applied to the extracted data. Results: Three main themes were evident in this study’s findings: childhood memories, friendships, and relationships, as well as the elders’ past. Additionally, older adults passed on a number of gems of wisdom to be shared with the younger generations. Conclusions: This study aided in revealing the resiliency, social connections, and life reflections of Omani older adults. These themes can guide the creation of age-inclusive laws, social support initiatives, and healthcare services specifically designed to satisfy the special requirements and ambitions of the elderly population. Based on these themes, this study recommended that the local community or society build a more sympathetic and compassionate atmosphere that honors and respects the accomplishments of this essential group by recognizing and comprehending the complex experiences of older adults. In addition, future studies could explore particular aspects of these older experiences and pinpoint solutions to improve their quality of life and wellbeing.
PsyCARE study: assessing impact, cost-effectiveness, and transdiagnostic factors of the Italian ministry of health’s “psychological bonus” policy
Field: PSYCHOLOGY

Background: The prevalence of anxiety and depression disorders is surging worldwide, prompting a pressing demand for psychological interventions, especially in less severe cases. Responding to this need, the Italian government implemented the “Psychological Bonus” (PB) policy, allotting 25 million euros for mental health support. This policy entitles individuals to a minimum of four to twelve psychological sessions. In collaboration with the National Board of Italian Psychologists, our study assesses this policy’s effectiveness. Indeed, the PsyCARE study aims to examine the utilization of the Psychological Bonus, evaluate its impact on adult and adolescent participants’ psychological well-being through pre- and post-intervention assessments and six-month follow-up, and conduct a longitudinal cost-effectiveness analysis of this policy. A secondary aim is to investigate the influence of these interventions on transdiagnostic factors, including emotion regulation and epistemic trust. Methods: The study involves licensed psychotherapists and their patients, both adults and adolescents, benefiting from the Psychological Bonus. Data collection is underway and set to conclude in December 2023. Psychotherapists will provide diagnostic information and assess patient functioning. In addition, patients will be evaluated on mental health aspects such as clinical symptoms, emotion regulation, epistemic trust, and quality of life. We will employ linear mixed-effects models to analyze the outcomes, accounting for both fixed and random effects to capture the hierarchical structure of the data. Discussion: We anticipate the study’s findings will highlight reduced psychological distress and improved quality of life for participants and demonstrate the Psychological Bonus policy’s cost-effectiveness. The study will gather data on the role of specific versus nonspecific therapeutic factors in psychotherapy while adopting a patient-tailored approach to identify effective therapeutic elements and examine transdiagnostic factors. Overall, this study’s findings will guide future measures within the Italian healthcare system, fostering a psychological health culture and providing valuable insights to the broader public. Study registration:
Assessment of the mind-body connection: preliminary psychometric evidence for a new self-report questionnaire
Field: PSYCHOLOGY

Objectives: While interoceptive self-report scales provide a foundation for measuring the mind-body connection, they variably consider other important factors that could influence interpretations of internal bodily sensations and perceptions related to mind-body integration. The proposed Body-Mind Connection Questionnaire (BMCQ) aimed to operationalise the notion that this construct involves three major components: (a) Interoceptive Attention, (b) Sensation-Emotion Articulation, and (c) Body-Mind Values. Methods: Following panel review and piloting with the target population, the developed BMCQ was evaluated in 316 participants (189 identifying as female) aged 18-50 (MAge=30.78), alongside established self-report measures of interoceptive sensibility, body awareness, sensory processing sensitivity, and alexithymia. We examined the BMCQ factor structure through exploratory factor analysis and analysed convergent and discriminant validity. Results: Exploratory factor analysis supported three scales of the BMCQ, which explained 54.03% of variance. Factor loadings (>0.44) and reliability indices (0.74 to 0.85) were acceptable. Inter-scale correlations suggested that the scales are distinct but related (rs=0.38 to 0.59). BMCQ scales were supported by convergent (r=0.33 to 0.67) and discriminant evidence (rs=0.01 to 0.39, p range n.s. to <.05). Conclusions: Preliminary psychometric properties indicate that the BMCQ is multidimensional and consists of three constructs that differentially relate to theoretically associated measures. Interoceptive Attention, Sensation-Emotion Articulation, and Body-Mind Values may serve as a basis for efficiently assessing the mind-body connection more holistically, which could be useful for developing interventions aimed at enhancing mind-body integration.
Assessing the Relationship between Prosocial Behavior and Well-Being: Basic Psychological Need as the Mediator
Field: PSYCHOLOGY

Previous research has established a positive link between prosocial behavior (PB) and psychological well-being. However, limited studies have explored the relationship between PB and well-being (WB), particularly among vocational students. Furthermore, the underlying mechanisms, including mediating factors, remain understudied in this context. This study aimed to investigate the association between PB and WB among vocational students while examining the mediating role of basic psychological needs. A sample of 221 vocational students (mean age = 19.68 years, SD = 1.57) completed anonymous questionnaires assessing PB, basic psychological needs, and WB. The results revealed a positive correlation between PB and WB in vocational students (r = 0.22, p < 0.01), with basic psychological needs partially mediating this relationship (β = 0.14, t = 10.85, p < 0.001, 95% CI = (0.18, 0.23)). These findings enhance our understanding of the association between PB and vocational students’ WB, shed light on the mechanisms involved, and offer insights into promoting the well-being of vocational students.
Meaning in Life and Loneliness as Mediators between COVID-19 Anxiety and Life Satisfaction in the Post-Pandemic among the General Population in Turkey: A Serial Mediation Model
Field: PSYCHOLOGY

The COVID-19 pandemic has impacted global society, leading to negative well-being and mental health outcomes. However, little is known about how COVID-19-related anxiety affects life satisfaction through psychological factors. This study examined the mediating roles of meaning in life and loneliness in the relationship between COVID-19 anxiety and life satisfaction in 333 Turkish general population (59.2% females; Mage = 33.9 ± 7.8). Participants completed measures of COVID-19 anxiety, life satisfaction, meaning in life, and loneliness. The results showed that COVID-19 anxiety predicted meaning in life, loneliness, and life satisfaction. Meaning in life predicted loneliness and life satisfaction, while loneliness predicted life satisfaction. Serial mediation analysis revealed that COVID-19 anxiety predicts life satisfaction through meaning in life and loneliness, even after controlling for age and gender. These findings contribute to our understanding of the underlying mechanisms between COVID-19 anxiety and life satisfaction, with implications for future research and practice.
Algorithms for All: Can AI in the Mortgage Market Expand Access to Homeownership?
Field: AI

Artificial intelligence (AI) is transforming the mortgage market at every stage of the value chain. In this paper, we examine the potential for the mortgage industry to leverage AI to overcome the historical and systemic barriers to homeownership for members of Black, Brown, and lower-income communities. We begin by proposing societal, ethical, legal, and practical criteria that should be considered in the development and implementation of AI models. Based on this framework, we discuss the applications of AI that are transforming the mortgage market, including digital marketing, the inclusion of non-traditional “big data” in credit scoring algorithms, AI property valuation, and loan underwriting models. We conclude that although the current AI models may reflect the same biases that have existed historically in the mortgage market, opportunities exist for proactive, responsible AI model development designed to remove the systemic barriers to mortgage credit access.
Hedgehog pathway in sarcoma: from preclinical mechanism to clinical application
Field: ONCOLOGY

Sarcomas are a diverse group of malignant neoplasms of mesenchymal origin. They develop rarely, but due to poor prognosis, they are a challenging and significant clinical problem. Currently, available therapeutic options have very limited activity. A better understating of sarcomas’ pathogenesis may help develop more effective therapies in the future. The Sonic hedgehog (Shh) signaling pathway is involved in both embryonic development and mature tissue repair and carcinogenesis. Shh pathway inhibitors are presently used in the treatment of basal cell carcinoma. Its increased activity has been demonstrated in many sarcomas, including osteosarcoma, Ewing sarcoma, chondrosarcoma, rhabdomyosarcoma, leiomyosarcoma, and malignant rhabdoid tumor. In vitro studies have demonstrated the effectiveness of inhibitors of the Hedgehog pathway in inhibiting proliferation in those sarcomas in which the components of the pathway are overexpressed. These results were confirmed by in vivo studies, which additionally proved the influence of Shh pathway inhibitors on limiting the metastatic potential of sarcoma cells. However, until now, the efficacy of sarcomas treatment with Shh pathway inhibitors has not been established in clinical trials. The reason for that may be the non-canonical activation of the pathway or interactions with other signaling pathways, such as Wnt or Notch. In this review, we present the Shh signaling pathway's role in the pathogenesis of sarcomas, including both canonical and non-canonical signaling. We also propose how this knowledge could be potentially translated into clinics.
Contributing and limiting factors to guideline-adherent therapy in senior and elderly breast cancer patients: a questionnaire-based cross-sectional study using clinical and cancer registry data in Germany
Field: ONCOLOGY

Purpose: Elderly cancer patients are less likely to be treated in accordance with evidence-based guideline recommendations. This study examines patient-related factors associated with deviations from guideline recommendations. Methods: Using medical documentation and cancer registry data, we investigated the treatment courses of female breast cancer patients aged 50 and older in Germany regarding compliance with German guidelines. Participants completed a questionnaire querying factors hypothesized to be associated with guideline adherence. We conducted univariate analyses to explore the data and select variables for multivariate logistic regression to estimate adjusted odds ratios. Results: Of 1150 participants, 206 (17.9%) were treated in deviation from guideline recommendations. Patients 70 years and older were more likely to be treated deviating from guideline recommendations than patients 50–69 years old (OR: 2.07; 95% CI: 1.52–2.80). Patients aged 50–69 years who reported that quality of life guided their treatment decision were more likely to be treated in deviation from guideline recommendations (AOR: 2.08; 95% CI: 1.11–3.92) than the elderly. In older patients, higher age was associated with an increased chance of receiving guideline-discordant care (AOR: 1.06; 95% CI: 1.01–1.11), as was depression diagnosed prior to cancer (AOR: 1.84; 95% CI: 1.00–3.40). Conclusion: Reasons for deviations from guideline recommendations in breast cancer patients differ by age. In decision-making concerning elderly patients, particular attention should be paid to those with pre-existing depressive disorders. Adequately addressing their needs and concerns could prevent inappropriate deviations from guideline recommendations.
From Policies to Practices: Factors Related to the Use of Inclusive Practices in Portugal
Field: PSYCHOLOGY

Inclusion is considered a foundation for quality education, and teachers’ inclusive practices are essential for success in mainstream classrooms. Portugal has been making progressive improvements in its policies for inclusive education, although there is little consistency in school practices within or between schools. Moreover, data identifying the personal and career variables relevant to teachers’ inclusive practices in Portugal are scarce. Therefore, the purpose of this study was to determine the relationship between teachers’ inclusive practices and personal and career-based characteristics, including gender, level of teaching, years of experience, roles performed at school, and perception of inclusive resources. The participants were 924 teachers who worked in private and public schools in Portugal. Regression analysis showed that perceived inclusive resources, level of teaching, and gender predicted variance in inclusive practices. Mean difference analyses revealed that teachers at the lower levels of teaching, females, and teachers reporting more inclusive resources had the highest scores for inclusive practices. These findings are discussed in terms of their practical relevance for inclusive school systems.
From Trustworthy Principles to a Trustworthy Development Process: The Need and Elements of Trusted Development of AI Systems
Field: AI

The current endeavor of moving AI ethics from theory to practice can frequently be observed in academia and industry and indicates a major achievement in the theoretical understanding of responsible AI. Its practical application, however, currently poses challenges, as mechanisms for translating the proposed principles into easily feasible actions are often considered unclear and not ready for practice. In particular, a lack of uniform, standardized approaches that are aligned with regulatory provisions is often highlighted by practitioners as a major drawback to the practical realization of AI governance. To address these challenges, we propose a stronger shift in focus from solely the trustworthiness of AI products to the perceived trustworthiness of the development process by introducing a concept for a trustworthy development process for AI systems. We derive this process from a semi-systematic literature analysis of common AI governance documents to identify the most prominent measures for operationalizing responsible AI and compare them to implications for AI providers from EU-centered regulatory frameworks. Assessing the resulting process along derived characteristics of trustworthy processes shows that, while clarity is often mentioned as a major drawback, and many AI providers tend to wait for finalized regulations before reacting, the summarized landscape of proposed AI governance mechanisms can already cover many of the binding and non-binding demands circulating similar activities to address fundamental risks. Furthermore, while many factors of procedural trustworthiness are already fulfilled, limitations are seen particularly due to the vagueness of currently proposed measures, calling for a detailing of measures based on use cases and the system’s context.
A psychometric study of an executive function assessment instrument (TDI-FE)
Field: PSYCHOLOGY

Background: This study aims to present and discuss the psychometric properties of executive functions, which were measured using the TDI-FE instrument. The analysis encompasses its internal structure, potential sensitivity to fatigue factors, relationships with external criteria, and diagnostic accuracy. Methods: The study sample comprised 382 students from Brazil, aged 6–8 years. Child development variables were screened using the TDI-FE and gold standard tests (Cancellation Attention and Trail Making Tests). The proposed scale comprised four activities: a test with fruit images with three tasks, and one memory game. Results: The one-factor model of EF of the TDI-FE failed to fit to the data. However, fit substantially improved once a latent fatigue factor was controlled in the model. The latent factor of EF assessed by the TDI-FE tasks was coherently associated with a series of external variables, including two popular collateral measures of EF. The diagnostic accuracy was reasonable, and a cut-off of 37 points produced 70% of sensitivity and 60% of specificity. Conclusion: Results indicated that the TDI-FE demonstrated sound psychometric properties and diagnostic accuracy, then consisting of an efficient alternative for the assessment of EFs in early childhood education. The study also proved the need to control for response biases such as fatigue in the latent variable models of EF. The TDI-FE is notable because of its low cost and easy application, and it might fulfill a need for instruments for individuals from different contexts at this stage of development in Brazil.
Modulatory Properties of Aloe secundiflora’s Methanolic Extracts on Targeted Genes in Colorectal Cancer Management
Field: ONCOLOGY

Colon tumors have a very complicated and poorly understood pathogenesis. Plant-based organic compounds might provide a novel source for cancer treatment with a sufficient novel mode of action. The objective of this study was to analyze and evaluate the efficacy of Aloe secundiflora’s (AS) methanolic extracts on the expression of CASPS9, 5-LOX, Bcl2, Bcl-xL, and COX-2 in colorectal cancer (CRC) management. Caco-2 cell lines were used in the experimental study. In the serial exhaustive extraction (SEE) method, methanol was utilized as the extraction solvent. Upon treatment of CASPS9 with the methanolic extracts, the expression of the genes was progressively upregulated, thus, dose-dependently increasing the rate of apoptosis. On the other hand, the expressions of 5-LOX, Bcl2, and Bcl-xL were variably downregulated in a dose-dependent manner. This is a unique novel study that evaluated the effects of AS methanolic extracts in vitro on CRC cell lines using different dosage concentrations. We, therefore, recommend the utilization of AS and the application of methanol as the extraction solvent of choice for maximum modulatory benefits in CRC management. In addition, we suggest research on the specific metabolites in AS involved in the modulatory pathways that suppress the development of CRC and potential metastases.