maxwellt/fedgrantsembedded huggingface dataset:
NIAID SBIR Phase II Clinical Trial Implementation Cooperative Agreement (U44 Clinical Trial Required)
Agency: National Institutes of Health
Posted: 2024-01-29 | Closing date: 2027-01-13
Cost sharing or matching requirement: No

This Notice of Funding Opportunity (NOFO) encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose to implement investigator-initiated clinical trials related to the research mission of the NIAID. This program provides support for hypothesis-driven, milestone-driven clinical trials. Although clinical trials not considered high-risk may be proposed, this program encourages high-risk clinical studies. High- risk does not imply human subject or patient risk, but rather defines a study that contains one or more of the following unique features: involves non-routine interventions, administration of an unlicensed product, or administration of a licensed product for an unapproved indication. Mechanistic studies are also encouraged and may be proposed under this program.

Eligibility: Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
Minority AIDS Initiative: A Pilot Program to Strengthen Prevention and Treatment Services for Substance Use Disorders, HIV/AIDS, and Other Infectious Diseases
Agency: Substance Abuse and Mental Health Services Adminis
Posted: 2024-05-13 | Closing date: 2024-07-12
Estimated total program funding: 5700000
Award ceiling: 700000
Award floor: 0
Expected number of awards: 8
Cost sharing or matching requirement: No

The purpose of this program is to provide substance use prevention, substance use disorder (SUD) treatment, HIV, and viral hepatitis prevention and treatment services for racial and ethnic individuals vulnerable to a SUD and/or mental health condition, HIV, viral hepatitis, and other infectious disease (e.g., sexually transmitted infections). Recipients will be expected to take a syndemic approach to SUD, HIV, and viral hepatitis by providing SUD prevention and treatment to racial and ethnic individuals at risk for or living with HIV.

Eligibility: Eligible applicants are States and Territories, including the District of Columbia, political subdivisions of States, Indian tribes, or tribal organizations (as such terms are defined in section 5304 of title 25), health facilities, or programs operated by or in accordance with a contract or award with the Indian Health Service, or other public or private non-profit entities, including faith-based organizations.
Mechanistic Studies on Social Behavior in Substance Use Disorder (R01 Basic Experimental Studies with Humans (BESH) Required)
Agency: National Institutes of Health
Posted: 2024-01-29 | Closing date: 2024-08-14
Cost sharing or matching requirement: No

The purpose of this notice of funding opportunity (NOFO) is to solicit applications proposing innovative transdisciplinary research that integrates approaches across social/cognitive neuroscience and other social sciences and will lead to a testable conceptual or computational model that provides mechanistic insights into social behavior and its relationships with the onset, trajectory and impact of Substance Use Disorders (SUD) and comorbidities. This NOFO is specifically soliciting applications proposing BESH research, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research.

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Promoting the Integration of Primary and Behavioral Health Care: Collaborative Care Model
Agency: Substance Abuse and Mental Health Services Adminis
Posted: 2024-03-19 | Closing date: 2024-05-20
Estimated total program funding: 5200000
Award ceiling: 900000
Award floor: 0
Expected number of awards: 5
Cost sharing or matching requirement: No

The purpose of this program is to support implementation of the Collaborative Care Model (CoCM). The CoCM is an evidence-based, integrated care approach that addresses mental and substance use conditions in primary care settings. Care is provided by a primary care team and includes a case manager, consulting psychiatrist, and other mental health professionals. Recipients will be expected to work with at least three primary care practices to develop the staffing and systems necessary to implement the CoCM. With this program, SAMHSA aims to increase the identification and treatment of mental health conditions for individuals who access care through primary care practices that too often go untreated and cause disability.

Eligibility: Eligibility for this program is statutorily limited to a state or appropriate state agency. Appropriate state agencies include the State Mental Health Authority, the Single State Agency (SSA) for substance use services, the State Medicaid agency, or the State Health Department. State agencies participating in this program will work with at least three primary care practices to develop the staffing and systems necessary to implement the CoCM.
The National Center for Mental Health Dissemination, Implementation and Sustainment Cooperative Agreement
Agency: Substance Abuse and Mental Health Services Adminis
Posted: 2024-04-11 | Closing date: 2024-06-10
Estimated total program funding: 7467006
Award ceiling: 7467006
Award floor: 0
Expected number of awards: 1
Cost sharing or matching requirement: No

The purpose of this program is to build the expertise of Center for Mental Health Services (CMHS) service, capacity building, and technical assistance recipients and organizations that oversee or directly provide mental health services to use science-based methods to implement, disseminate, and sustain services. The MHDIS recipient will be expected to provide: (1) training and technical assistance (TTA) on the planning implementation, adaptation, and sustainment of a new/existing service and (2) localized, targeted, and intensive technical assistance (TA) to CMHS recipients and other mental health providers to improve the process of implementation, dissemination, and sustainment of services.

Eligibility: Eligible applicants are States and Territories (Guam, the Commonwealth of Puerto Rico, the Northern Mariana Islands, the Virgin Islands, American Samoa, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau), including the District of Columbia, political subdivisions of States, Indian tribes, or tribal organizations (as such terms are defined in Section 5304 of title 25), health facilities, or programs operated by or in accordance with a contract or award with the Indian Health Service, or other public or private non-profit entities.
Mechanistic Studies on Social Behavior in Substance Use Disorder (R01 Clinical Trials Not Allowed)
Agency: National Institutes of Health
Posted: 2024-01-29 | Closing date: 2024-08-14
Award ceiling: 425000
Cost sharing or matching requirement: No

The purpose of this notice of funding opportunity (NOFO) is to solicit applications proposing mechanistic transdisciplinary research in animal models that integrates approaches across social/cognitive neuroscience with perspectives from fields with complementary approaches to the study of social behavior, with the goal of developing a testable conceptual or computational model that provides mechanistic insights into social behavior and its relationships with the onset, trajectory and impact of Substance Use Disorders (SUD) and comorbidities. This NOFO is intended to support basic or translational research in non-human animal models, including secondary analysis of data from research in animal models. Applications including studies involving human subjects should submit under one of the companion NOFOs.

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
FY2024 - Historic Preservation Fund- Annual State Historic Preservation Office Grants
Agency: National Park Service
Posted: 2024-01-29 | Closing date: 2024-05-30
Electronically submitted applications must be submitted no later than 11:59 PM, ET, on the listed application due date.
Estimated total program funding: 62150000
Award ceiling: 2200000
Award floor: 100000
Cost sharing or matching requirement: Yes

This funding program supports the operation of State Historic Preservation Offices (SHPOs) in the 50 states, 5 territories, 3 Freely Associated States, and District of Columbia within allowable program areas described in the Historic Preservation Fund Grants Manual. Where relevant, staff and projects must comply with the appropriate Secretary of the Interior’s Standards.The purposes of this program are to provide matching grants to States for the identification, evaluation, and protection of historic properties by such means as: survey, planning, technical assistance, physical preservation, Federal tax incentives available for historic properties, nominations to the National Register of Historic Places, distribution of funding to Certified Local Governments, and to assist Federal, State, and Local Government agencies, nonprofit organizations and private individuals in carrying out historic preservation activities. Awards under this program must comply with and support 54 U.S.C. 3001 et seq. (commonly known as the National Historic Preservation Act). 

Eligibility: In accordance with the National Historic Preservation Act as amended, 54 USC 3001, this funding opportunity is limited to:State governments, as defined in 54 USC 3001 et seq. also known as the National Historic Preservation Act, as amended. Further eligible applicants are defined in 54 USC 302902 - Grants to States; 54 USC 302908 - Grants to the Federated States of Micronesia, the Republic of the Marshall Islands, the Republic of Palau; and specifically in 54 USC 300317 – States.  One nonprofit organization, Ohio History Connection, is eligible to apply serving as the Ohio State Historic Preservation Office.  
Historic Preservation
Minority AIDS Initiative: Integrated Behavioral Health and HIV Care for Unsheltered Populations Pilot Project
Agency: Substance Abuse and Mental Health Services Adminis
Posted: 2024-05-09 | Closing date: 2024-07-08
Estimated total program funding: 2600000
Award ceiling: 650000
Award floor: 0
Expected number of awards: 4
Cost sharing or matching requirement: No

The purpose of this program is to pilot a portable clinical care approach to underserved populations experiencing unsheltered homelessness by integrating behavioral health, HIV treatment and prevention services.

Eligibility: Eligible applicants are States and Territories, including the District of Columbia, political subdivisions of States, Indian tribes, or tribal organizations (as such terms are defined in section 5304 of title 25), health facilities, or programs operated by or in accordance with a contract or award with the Indian Health Service, or other public or private non-profit entities, including faith-based organizations.
NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)
Agency: National Institutes of Health
Posted: 2024-01-29 | Closing date: 2027-01-13
Cost sharing or matching requirement: No

This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for implementation of investigator-initiated, high-risk clinical trials and mechanistic studies associated with high-risk clinical trials. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development of future therapeutic modalities. Investigators are encouraged to visit the NIAID website for additional information about the research mission and high-priority research areas of the NIAID (https://www.niaid.nih.gov/research/role). Only one clinical trial may be proposed in each NIAID Clinical Trial Implementation Cooperative Agreement (U01) application

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Continuous Ketone Monitoring for the Safe Use of Sodium-glucose Cotransporter-2 Inhibitors in Type 1 Diabetes (R01 Clinical trial Required)
Agency: National Institutes of Health
Posted: 2024-01-30 | Closing date: 2024-06-27
Award ceiling: 500000
Cost sharing or matching requirement: No

Sodium-glucose co-transporter-2 inhibitors (SGLT2i) that were developed for the treatment of type 2 diabetes (T2D) have significant protective effects for cardiac and renal diseases for people with and without diabetes. However, SGLT2i are not currently approved for individuals with type 1 diabetes (T1D) and there is an increased risk of diabetic ketoacidosis (DKA) for this population. Despite this concern, these drugs are increasingly being prescribed off-label for people with T1D. Continuous ketone monitoring (CKM) is a rapidly evolving technology that could be utilized clinically to prevent DKA by an early warning of elevations in ketone levels.The purpose of this NOFO is to solicit applications for studies that will develop and test risk mitigation strategies that involve the clinical integration of CKM for the safe use of SGLT2i for people living with T1D so that they may benefit from the cardiac and renal protection and glucose-lowering effects of this drug class. The NOFO will support short-term, clinical trials to gain and disseminate knowledge on safety and glucose control with CKM and SGLT2i use.Possible topics include testing optimal insulin delivery in open and closed loop systems or multiple daily injections and developing clinical protocols to control or ameliorate elevated ketone levels in individuals with T1D who are receiving adjunct therapy with SGLT2i.

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
FY2024 - Historic Preservation Fund- Annual Tribal Historic Preservation Office Grants
Agency: National Park Service
Posted: 2024-01-30 | Closing date: 2024-05-30
Electronically submitted applications must be submitted no later than 11:59 PM, ET, on the listed application due date.
Estimated total program funding: 23000000
Award ceiling: 200000
Award floor: 30000
Cost sharing or matching requirement: No

This funding program supports the operation of Tribal Historic Preservation Offices (THPOs) within allowable program areas described in the Historic Preservation Fund Grants Manual. Where relevant, staff and projects must comply with the appropriate Secretary of the Interior’s Standards and Guidelines for Archeology and Historic Preservation.The purpose of this program is to provide grants to THPOs for the identification, evaluation, and protection of historic properties as outlined in the National Historic Preservation Act (NHPA) by such means as: survey, planning, technical assistance, physical preservation, review of Federal undertakings, education, listing in the National Register of Historic Places and Tribal Registers. These grants assist THPOs in carrying out the NHPA historic preservation activities that a Tribe agreed to assume from the State Historic Preservation Office, on tribal lands, under their Partnership agreement with the National Park Service. Awards under this program must comply with and support 54 USC 3001 et seq. 

Eligibility: Tribal governments with signed Memorandum of Agreements with the National Park Service to assume the duties of the State Historic Preservation Office on Tribal lands, as defined in 54 USC 3001 et seq. also known as the National Historic Preservation Act.
Historic Preservation
Senior Community Service Employment Program (SCSEP) Optional Demonstration Grants on Sector-Based Training for Low-Income Older Adult Workers
Agency: Employment and Training Administration
Posted: 2024-04-10 | Closing date: 2024-06-10
Applications must be submitted electronically no later than 11:59 pm Eastern Time.
Estimated total program funding: 19000000
Award ceiling: 5000000
Award floor: 2000000
Expected number of awards: 6
Cost sharing or matching requirement: No

Questions regarding this Funding Opportunity Announcement (FOA) may be emailed to SCSEP.OGM@dol.gov; however, please note there is limited information that may be shared with the public.

Eligibility: To be eligible to apply for the SCSEP Sector Training Demonstration Grant funding under this FOA, applicants must be a current SCSEP National grantee, having received an award in Program Year 2020 under funding opportunity number FOA-ETA-20-09.  To be eligible to receive an award for the SCSEP Sector Training Demonstration Grant funding under this FOA, the applicant must also concurrently apply to and be selected for the PY 2024 SCSEP National Grant Competition (FOA-ETA-24-11), which is a separate funding opportunity announcement that published to grants.gov in March 2024.
U.S.  Embassy Bujumbura Public Diplomacy Section (PDS) Annual Program Statement
Agency: U.S. Mission to Burundi
Posted: 2024-01-31 | Closing date: 2024-06-28
Award ceiling: 20000
Award floor: 0
Expected number of awards: 10
Cost sharing or matching requirement: No

The U.S. Embassy Burundi Public Diplomacy Section (PDS) of the U.S. Department of State is pleased to announce an open competition for organizations to submit applications to carry out a program or project with funding through the Public Diplomacy Small Grants Program. This is an Annual Program Statement, outlining our funding priorities, the strategic themes we focus on, and the procedures for submitting requests for funding. Please carefully follow all instructions below.Purpose of Small Grants: PDS Bujumbura invites proposals for programs that strengthen ties between the United States and Burundi through cultural and exchange programming that highlights shared values and promotes bilateral cooperation. All programs must include an American element, priority, goal, or a connection with U.S. expert(s), organization(s), or institution(s), in a specific field that will promote increased understanding of U.S. policy and perspectives. Applicants are strongly encouraged to partner with English Clubs, American Spaces, or U.S. exchange program alumni to conduct activities.

Eligibility: 1.Eligible Applicants    The Public Diplomacy Section encourages applications from U.S. and Burundian entities:  • Registered not-for-profit organizations, including think tanks and civil society/non-governmental organizations with programming experience and  • Non-profit or governmental educational institutions    2.Cost Sharing or Matching     Cost sharing is not required.    3.Other Eligibility Requirements    Applicants are only allowed to submit one proposal per organization. If more than one proposal is submitted from an organization, all proposals from that institution will be considered ineligible for funding.    In order to be eligible to receive an award, all organizations must have a Unique Entity Identifier (UEI) number issued via www.SAM.gov as well as a valid registration on www.SAM.gov. Organizations should go to SAM.gov to complete their registration, a UEI will be generated as part of the SAM.gov registration process.
Public Diplomacy
State Opioid Response (SOR)/Tribal Opioid Response (TOR) Technical Assistance
Agency: Substance Abuse and Mental Health Services Adminis
Posted: 2024-05-15 | Closing date: 2024-07-15
Estimated total program funding: 18500000
Award ceiling: 18500000
Award floor: 0
Expected number of awards: 1
Cost sharing or matching requirement: No

The purpose of this program is to advance the provision of trauma-informed, culturally relevant, and evidence-based substance use-related approaches and interventions across the country and across the lifespan to reduce the impacts of opioid and stimulant misuse and use disorders on individuals, families, and communities. 

Eligibility: Eligible applicants are States and Territories, including the District of Columbia, political subdivisions of States, Indian tribes, or tribal organizations (as such terms are defined in section 5304 of title 25), health facilities, or programs operated by or in accordance with a contract or award with the Indian Health Service, or other public or private non-profit entities.
NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)
Agency: National Institutes of Health
Posted: 2024-02-01 | Closing date: 2026-11-13
Award ceiling: 350000
Cost sharing or matching requirement: No

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to three years (R61 phase) of support for milestone-driven testing of pharmacokinetics, bioavailability, and assessment of the natural products effect (i.e., measure of mechanism of action) when used by humans on a specified target measure. If milestones in the R61 phase are achieved, up to 3 years of additional support (R33 phase) may be awarded to replicate the impact of the natural product on target engagement(s) when used by humans and assess whether there is an association between the degree of the impact on the target engagement and clinical outcomes in a participant population. Applications are encouraged to design R33 studies to determine how to optimize the impact of the natural product on the target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to impact the same target engagement measure; or study the impact of the natural product in a population that is more responsive,

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)
Agency: National Institutes of Health
Posted: 2024-02-01 | Closing date: 2026-11-13
Award ceiling: 1050000
Cost sharing or matching requirement: No

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to 3 years support for studies to replicate the impact of the natural product on target engagement when used by humans, and assess whether there is an association between the degree of the impact on target engagement and functional or clinical outcomes in a patient population. Applications are encouraged to design studies to determine how to optimize the impact of the natural product on target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to engage the same target; or study the impact of the natural product in a target population that is more responsive. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This R33 funding mechanism is intended to accelerate the translation of emerging basic science findings about natural products into early-stage clinical testing to determine whether continued clinical research is warranted. This NOFO will not support efficacy or effectiveness trials, nor will

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)
Agency: National Institutes of Health
Posted: 2024-02-01 | Closing date: 2026-11-13
Award ceiling: 350000
Cost sharing or matching requirement: No

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natural product produces a reproducible and measurable impact on target engagement (i.e., measure of the mechanism of action). Only in cases when it is not possible/practical to measure target engagement in the patient population of interest or when there is a fundamental understanding of the products mechanism of action will this preliminary data requirement be waived. Applications submitted to this NOFO should propose a mid-phase clinical trial to do the following: determine the optimal dose or formulation of a given natural product for use in a future multi-site efficacy trial; or determine which patient phenotypes will be responders versus non-responders to the natural product to inform inclusion/exclusion criteria of a future efficacy trial. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This NOFO will not support single-site or multi-site efficacy or effectiveness trials, nor will it support trials to test natural products for the treatment or prevention of cancer. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NO

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Computer and Information Science and Engineering Research Expansion Program
Agency: National Science Foundation
Posted: 2024-02-02 | Closing date: 2025-02-07
Estimated total program funding: 10000000
Expected number of awards: 20
Cost sharing or matching requirement: No

With this solicitation, the National Science Foundation's (NSF) Directorate for Computer and Information Science and Engineering (CISE) is continuing its support of research expansion for Minority-Serving Institutions (MSIs). The goal of the CISE MSI program is to broaden participation by increasing the number of CISE-funded research projects from MSIs and to develop research capacity toward successful submissions to core CISE programs. MSIs are central to inclusive excellence: they foster innovation, cultivate current and future undergraduate and graduate computer and information science and engineering talent, and bolster long-term U.S. competitiveness.

Eligibility: *Who May Submit Proposals: Proposals may only be submitted by the following:   - CISE MSI promotes capacity building and institutional infrastructure development for CISE programs at MSIs, as well as partnerships between MSIs and non-MSIs across the nation. These activities are intended to be a driving force for strengthening and diversifying U.S. research and education pathways and providing historically marginalized communities new opportunities in STEM careers. Proposals may be submitted only by accredited Institutions of Higher Education (IHEs) that<span class="cf0">are recognized as Minority Serving Institutions (</span><a class="cf0" href="https://www2.ed.gov/about/offices/list/ocr/edlite-minorityinst.html"><span class="cf1">https://www2.ed.gov/about/offices/list/ocr/edlite-minorityinst.html</span></a><span class="cf0"> ).</span>    <span class="cf0">Institutions that have received NSF awards totaling more than $2 million dollars, within the past five years from the CISE programs listed in Section II combined, are not eligible to serve as lead institutions, but may participate as non-lead collaborators. (See Section II Program Description)</span>       *Who May Serve as PI:  A MSI faculty member should serve as the lead principal investigator(s) on any proposal submission. <br />
Regional Centers for Public Health Preparedness and Response
Agency: Centers for Disease Control - ORR
Posted: 2024-03-21 | Closing date: 2024-05-23
Electronically submitted applications must be submitted no later than 11:59 pm ET on the listed application due date.
Estimated total program funding: 40000000
Award ceiling: 800000
Award floor: 400000
Expected number of awards: 10
Cost sharing or matching requirement: No

The purpose of the NOFO is to establish and maintain a network of Regional Centers for Public Health Preparedness and Response to increase implementation of evidence-based strategies and interventions (EBSIs) and to improve public health preparedness and response, as informed by the needs of the communities involved. Support will be provided for up to ten centers to determine and support implementation of activities needed to increase use of EBSIs that will improve public health preparedness and response, as informed by the needs of the communities as described in regional workplans. The goal is to fund one center in each of the 10 HHS Regions. Each center will1) Coordinate relevant activities with applicable State, local, and Tribal health departments and officials, health care facilities, and health care coalitions to improve public health preparedness and response, as informed by the needs of the community, or communities involved.2) Develop and implement activities to support focus areas and objectives created by a regional coordinating body in 2023-24.3) As determined necessary by the CDC, and based on the availability of funding, support further implementation of evidence-based practices, or conduct research, evaluation, translation or dissemination necessary to address active or anticipated public health emergencies.4) One center will be awarded additional funds to support coordination and convening of centers and provide technical assistance and training as needed. For the NOFO and application information Zoom webinar, scheduled on Monday, April 1, 2024, 2:00 to 3:30 p.m. ET., please register at https://cdc.zoomgov.com/meeting/register/vJItc-uorjIpE_T4tMi0-EeW8IrJKPJd-uI.

Eligibility: Institutions of higher education, including accredited schools of public health, or other Nonprofit private entities (having a 501(c)(3) status with the IRS, other than institutions of higher education).Additional Info on Eligibility: There will be an open competition among the above referred eligible entities within each of the 10 HHS Regions.Applicant institutions or entities must be based in the region they are applying to represent.
LWCF Administrative Grant Award - FY24
Agency: National Park Service
Posted: 2024-02-02 | Closing date: 2024-07-12
Estimated total program funding: 24886099
Award ceiling: 1960000
Award floor: 200000
Expected number of awards: 28
Cost sharing or matching requirement: Yes

PLEASE ENSURE YOU ARE FAMILIAR WITH ALL THE INFORMATION IN THE ABOVE NOTICE OF FUNDING OPPORTUNITY BEFORE APPLYING.With few notable exceptions in allowable periods of performance, 2024 administrative grant applications and awards will be the same as 2023 (see information for the applicant below). Applicants no longer need to limit personnel expenditures to one year and the overall grant to three. We recognize the strategic value in awarding a 4-5 year administrative grant that can be successively amended in cost and scope. This prevents overlapping periods of performance and simplifies reporting. If you have already been awarded an administrative grant in 2023, work with your NPS program officer to advance a cost increase amendment, not a new 2024 administrative grant award. Award amounts are still recommended to be greater than $200,000 and less than 7% of the state’s apportionment. Applications with proposed awards outside of this range should justify the request in the budget narrative according to the program goals of: 1) improving participation in ORLP and formula grant programs, 2) addressing deficient formula grant implementation areas, 3) improving monitoring of LWCF assisted parks and sub-recipients. Recommendations to applicants include: 1) work with your NPS program officer to review the application prior to submission, 2) pay special attention to Budget Object Classifications definitions within the SF424a instructions and use these BOC’s in the budget narrative to make sure there is tight correspondence, 3) include a signed, written request for reimbursement of any equipment costs included in budget, and 4) allow time for revisions to the SF424a.
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products (Collaborative UG3/UH3 Clinical Trial Required)
Agency: National Institutes of Health
Posted: 2024-02-02 | Closing date: 2026-07-14
Cost sharing or matching requirement: No

This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for investigator-initiated, multi-site, clinical trials (Phase III and beyond) to study the effects of natural products (i.e. botanicals, probiotics, and products marketed as dietary supplements) in NCCIH designated areas of high research priority. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Applicants should describe plans for a Clinical Coordinating Center to develop and implement the proposed multi-site clinical trial. The objective of the Clinical Coordinating Center application is to provide the scientific rationale and a comprehensive scientific and operational plan for the clinical trial. Clinical Coordinating Center applications are expected to describe plans for project management, participant recruitment and retention strategies, performance milestones, scientific conduct, and dissemination of results. Clinical Coordinating Center applications submitted under this NOFO will utilize a two-phase, milestone-driven, cooperative agreement (UG3/UH3) funding mechanism. In addition, an accompanying Data Coordinating Center application, submitted under PAR-20-219, proposing a data analysis and data management plan for the clinical project is required. Both a Clinical Coordinating Center application and a corresponding Data Coordinating Center (DCC) application need to be submitted simultaneously for consideration by NCCIH. For additional information about the mission, strategic vision, and research priorities of the NCCIH, applicants are encouraged to consult the NCCIH website: (https://nccih.nih.gov/about/plans).

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Posted: 2024-02-02 | Closing date: 2026-10-06
Cost sharing or matching requirement: No

Reissue of RFA-NS-19-011: The purpose of the NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award is to support a defined pathway across career stages for outstanding graduate students who are from backgrounds that are nationally underrepresented in neuroscience research. This two-phase award will facilitate completion of the doctoral dissertation and transition of talented graduate students to strong neuroscience research postdoctoral positions, and will provide career development opportunities relevant to their long-term career goal of becoming independent neuroscience researchers.

Eligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
LWCF State Assistance Formula Grants - Acquisition & Construction - FY24
Agency: National Park Service
Posted: 2024-02-02 | Closing date: 2024-07-12
Estimated total program funding: 450000000
Award ceiling: 15000000
Award floor: 10000
Expected number of awards: 350
Cost sharing or matching requirement: Yes

This notice of funding opportunity (NOFO) is to advise States, local units of government, and Indian Tribes of the potential availability of funds in their State for grants from the Land and Water Conservation Fund (LWCF) to acquire and/or develop lands for public outdoor recreation purposes. The State and Local Assistance Program was created when the LWCF Act was enacted September 3, 1964. It helps fulfill the LWCF Acts purpose to assist in preserving, developing, and assuring accessibility to present and future generations of U.S. citizens and visitors such quality and quantity of outdoor recreation resources as may be available and are necessary and desirable for individual active participation in such recreation and to strengthen the health and vitality of the citizens of the United States. This is accomplished in part by authorizing and providing grants to States, and through States to local units of government and Indian tribes, for projects that acquire lands and waters for parks and other outdoor recreation spaces, as well as develop new or renovate existing outdoor recreation facilities. Outdoor recreation areas and facilities must be publicly owned as well as open to the general public and not limited to special groups. The LWCF State and Local Assistance program is operated by the National Park Service (NPS) in partnership with designated lead agencies in each of the 50 States plus American Samoa, the District of Columbia, Guam, the Northern Mariana Islands, Puerto Rico, and the U.S. Virgin Islands. Each fiscal year Congress allocates money from the LWCF for this program, which is in turn allocated to the States based on a legislative formula. To be eligible for the funding, States must have a current State Comprehensive Outdoor Recreation Plan (SCORP) in place that assesses demand and need for outdoor recreation resources and sets priorities for the use of LWCF funds. The process for applying for a grant begins at the State or Territory level. Entities interested in applying for an LWCF grant must contact their State lead agency to find out details about the availability of funds, timing of grant process, State program priorities, funding criteria, etc.The lead agency is responsible for soliciting project proposals from other State agencies, local units of government, and Indian Tribes and for conducting competitions to identify the projects that can best advance the goals or meet the needs identified in the States SCORP. The top ranked projects, within the funds available, are nominated to the NPS for consideration and final decision, as well as the actual award of a grant. Prospective applicants should be able to specifically describe how their project would address priority outdoor recreation needs and goals as identified in the States SCORP.
LWCF State Assistance Formula Grants - Planning - FY24
Agency: National Park Service
Posted: 2024-02-02 | Closing date: 2024-07-12
Estimated total program funding: 1500000
Award ceiling: 250000
Award floor: 2500
Expected number of awards: 10
Cost sharing or matching requirement: Yes

This notice of funding opportunity is to advise the State lead agencies for Land and Water Conservation Fund (LWCF) of the availability of funds for projects to develop or update their State-wide Comprehensive Outdoor Recreation Plan (SCORP) or supporting elements of it, as well as for other types of recreation planning projects. The LWCF Act requires each state to develop and maintain a SCORP for overall program eligibility for LWCF grants. The LWCF State and Local Assistance program is implemented by the National Park Service (NPS) in partnership with designated lead agencies in each of the 50 States as well as American Samoa, the District of Columbia, Guam, the Northern Mariana Islands, Puerto Rico, and the U.S. Virgin Islands. Each fiscal year Congress allocates money from the LWCF for this program, which is in turn allocated to the States based on a legislative formula. To be eligible for the funding, States must have a current SCORP in place that assesses demand and need for outdoor recreation resources and sets priorities for the use of LWCF funds. Projects selected for LWCF funding should address priority needs or goals of the SCORP. The NPS must review and approve each State’s SCORP, which is updated at least once every 5 years. The LWCF Grant Assistance Manual establishes the eligibility, procedural, and programmatic requirements for LWCF grants. A copy of the current volume of the LWCF Financial Assistance Manual (Volume 72, October 1, 2023) can be found at FEDERAL FINANCIAL ASSISTANCE MANUAL (nps.gov). Chapter 2 of the Manual outlines the SCORP process and requirements. 

Planning grants for LWCF projects.