EMERGING FRONTIERS IN RESEARCH AND INNOVATION (EFRI): Biocomputing through EnGINeering Organoid Intelligence (BEGIN OI)
Agency: National Science Foundation
Posted: 2023-11-16 | Closing date: 2024-12-12
Estimated total program funding: 30000000
Cost sharing or matching requirement: No

The Emerging Frontiers in Research and Innovation (EFRI) program of the NSF Directorate for Engineering (ENG) serves a critical role in helping ENG focus on important emerging areas in a timely manner. The EFRI Biocomputing through EnGINeering Organoid Intelligence (BEGIN OI) solicitation supports foundational and transformative research to advance the design, engineering, and fabrication of organoid systems that are capable of processing information dynamically while interfacing with non-living systems. This solicitation will be coordinated with the Directorate for Biological Sciences (BIO), the Directorate for Computer and Information Science and Engineering (CISE), the Directorate for Mathematical and Physical Sciences, and the Directorate for Social, Behavioral, and Economic Sciences (SBE). The EFRI program seeks proposals with potentially transformative ideas that represent an opportunity for a significant shift in fundamental engineering knowledge with strong potential for long term impact on national needs or a grand challenge. The proposals must also meet the detailed requirements delineated in this solicitation. INFORMATIONAL WEBINAR: The Emerging Frontiers and Multidisciplinary Activities (EFMA) Office will host an informational webinar in November 2023 to discuss the EFRI FY 2024/25 solicitation and to answer questions. Details on how to join this webinar will be posted on the EFRI websiteand Solicitation Website.

Eligibility: *Who May Submit Proposals: Proposals may only be submitted by the following:   -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities.   -Institutions of Higher Education (IHEs) - Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting      on behalf of their faculty members.Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an      international branch campus of a US institution of higher education (including through use of subawards and consultant arrangements), the proposer must explain      the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.  *Who May Serve as PI:  For proposals submitted by Institutions of Higher Education, the lead Principal Investigator (PI) must be full-time, tenured or tenure-track faculty. For proposals submitted by Non-Profit, Non-Academic Organizations, the lead PI must meet all of the following requirements: (1) the PI has a continuing appointment that is expected to last the four years of an EFRI grant; (2) the appointment has substantial research responsibilities; and (3) the proposed project relates to the PI&rsquo;s job responsibilities as well as to the mission of the department or organization.    A minimum of one PI and two co-PIs must participate in each proposal. Either the PI or one of the co-PIs must have a full-time, tenured or tenure-track faculty appointment within a College/Department of Engineering.