Improvements in the Manufacture or Production of an Albumen- tannin Compound.
Year: 1896

page_text: Date of Application, 16th June, 1896
Complete Specification Left, 6th July, 1896-Accepted, 8th Aug., 1896
PROVISIONAL SPECIFICATION.
Improvements in the Manufacture or Production of an Albumen-
tannin Compound.
A communication from Messrs. KNOLL & Co., of Ludwigshafen on the Rhine,
Germany, Chemical Manufacturers."
1, WILLIAM LLOYD WISE, of 46 Lincoln's Inn Fields, in the County of
London, Consulting Engineer and Chartered Patent Agent, do hereby declare the
nature of this invention to be as follows:--
In the Specification of another application for Letters Patent filed by me
dated 23 March 1896 No. 6410 there is described the manufacture or production
of an albumen-tannin compound, capable of resisting the action of the juices of
the stomach, so that the astringent properties of the compound shall come into
action only in the intestines, for which purpose the precipitate obtained by mixing
aqueous solutions of tannic acid and albumen, was repeatedly washed in order to
free it of any surplus tannic acid after which it was filtered and pressed to convert
it into a dry state, and was finally exposed during a prolonged period to a
temperature of from about 110° to 150° Centigrade.
Now according to the present invention it has been found, that instead of heating
the precipitate as described, the same result can be attained by treating the
precipitate with a substance or substances such for examples as alcohol, acids,
formaldehyde etc., which has or have the effect of rendering the albumen-tannin
compounds difficultly digestible in the juices of the stomach. This treatment may
take place at the ordinary temperature of the atmosphere, or at a higher temperature
and with or without the addition of salts.
The following methods are given by way of examples for manufacturing albumen-
tannin compounds of the kind referred to, according to this invention.
1. The precipitate of albumen-tannic acid, obtained as described in my said
prior Specification No. 6410 of 1896 by separately dissolving tannic acid and
albumen in water and afterwards mixing the two solutions, is allowed to remain
in contact, for say 24 hours, with about three times its volume of alcohol
(ninety per cent.) or with about twice its volume of muriatic acid (25 per cent.)-
after which the resulting substance or mass is filtered and the residue washed
and dried.
2. About ten kilogrammes of albumen and twenty kilogrammes of tannic acid
are separately dissolved in an alkaline solution and the two solutions mixed
together and the mixture introduced, either warm or cold into a surplus quantity
of acid, for instance muriatic acid. The resulting precipitate is then filtered,
washed and dried.
The result of each treatment is the same as that obtained by the treatment
described in my said former specification, namely, the production of an albumen-
tannic compound capable of resisting the action of the juices of the stomach and
coming into action in the intestines as an astringent.
Dated this 19th don
T1900
W. LLOYD WISE,
46 Lincoln's Inn Fields, London, W.C., Chartered Patent Agent.

page_text: Improvements in the Manufacture or Production of an Albumen-
tannin Compound.
A communication from Messrs. KNOLL & Co., of Ludwigshafen on the Rhine,
Germany, Chemical Manufacturers.
1, WILLIAM LLOYD WISE, of 46 Lincoln's Inn Fields, in the County of
London, Consulting Engineer and Chartered Patent Agent, do hereby declare
the nature of this invention and in what manner the same is to be
performed to be particularly described and ascertained in and by the following
statement:
In the Specification of another application for Letters Patent filed by me
dated 23 March 1896 No. 6410, there is described the manufacture or production
of an albumen-tannin compound, capable of resisting the action of the juices of
the stomach, so that the astringent properties of the compound shall come into
action only in the intestines, for which purpose the precipitate obtained by mixing
aqueous solutions of tannic acid and albumen, are repeatedly washed in order
to free it of any surplus tannic acid, after which it is filtered and pressed to
convert it into a dry state, and is finally exposed, during a prolonged period, to a
temperature of from about 110° to 150° Centigrade.
Now according to the present invention it has been found, that instead of
heating the precipitate as described, the same result can be attained by treating
the precipitate with a substance such for example as alcohol, an acid, formic
aldehyde etc., that has the effect of rendering the albumen-tannin compounds
difficultly digestible in the juices of the stomach. This treatment may take place
at the ordinary temperature of the atmosphere or at a higher temperature, and
with or without the addition of salts.
The following methods are given by way of examples for manufacturing
albumen-tannin compounds of the kind referred to, according to this invention.
1. The precipitate of albumen-tannic acid, obtained as described in my said
prior Specification No. 6410 of 1896 namely by separately dissolving tannic acid
and albumen in water and afterwards mixing the two solutions, is allowed to remain
in contact, for say 24 hours, with about three times its volume of alcohol
(vinety per cent.), or with about twice its volume of muriatic acid (25 per cent.)-
after which the resulting substance or mass is filtered and the residue washed and
dried.
2. About ten kilogrammes of albumen and twenty kilogrammes of tannic acid
are separately dissolved in an alkaline solution and the two solutions mixed
together and the mixture introduced, either warm or cold, into an excess of acid,
for instance muriatic acid. The resulting precipitate is then filtered, washed and
dried.
The result of each treatment is the same as that obtained by the treatment
described in my said former specification, namely, the production of an albumen-
tannic compound or albuminate of tannin that is insoluble in the juices of the
stomach but capable of acting in the intestines as an astringent.
Having now particularly described and ascertained the nature of the said inven-
tion and in what manner the same is to be performed I declare that what I
claim is :-
The herein described improved manufacture of an albumen-tannin compound or
albuminate of tannin insoluble in the stomach but effective in the intestines, by
treating the precipitate obtained by mixing solutions of tannic acid and albumen

page_text: with a substance such as alcohol, or an acid, or formic aldehyde, or by treating an
alkaline solution containing the said precipitate with an excess of acid, substantially
as herein described.
Dated this 6th day of July 1896.
W. LLOYD WISE,
46 Lincoln's Inn Fields, London, W.C., Chartered Patent Agent.