A Manufacture of Pharmaceutic Preparations, for Use more particularly in Cases of Anemia and for Weak Throats.
Year: 1893

page_text: Date of Application, 9th Feb., 1893
Complete Specification Left, 8th Nov., 1893-Accepted, 9th Dec., 1893
PROVISIONAL SPECIFICATION.
A Manufacture of Pharmaceutic Preparations, for Use more
particularly in Cases of Anemia and for Weak Throats.
We, WILLIAM WEBSTER, F.C.S., of Glencot, Blackheath Park, Blackheath,
and THOMAS MOORE, F.R.C.S. of Lee Terrace, Blackheath, both in the County
of Kent, do hereby declare the nature of this invention to be as follows:-
Our invention has for its object a manufacture of pharmaceutical preparations
consisting mainly of aqueous solutions containing oxides and carbonates of iron, to
which is added a body such as glycerine which tends to partially neutralise the
astringent action which iron has upon the human system.
For this purpose we in the first place add to the water a small proportion of
common salt and we then subject it to electrolytic action by means of iron
electrodes immersed therein, thereby obtaining oxides and carbonates in solution,
the strength of the current employed being by preference not greater than
Toth ampère per square foot of surface of the electrodes employed, in order not to
cause waste of iron.
.
"
Either before or after the above described action we add to the water glycerine,
by preference in the proportion of about 40 minims to every ounce of water, such
admixture having the effect, both of retarding the oxidation of the neutral iron
salt in solution and of partially preventing the astringent action of the iron when
taken internally.
The above described preparation is applicable with very beneficial results in
cases of anemia, and is also valuable as a gargle for weak throats.
This preparation may also be prepared in the first instance in an atmosphere of
carbonic acid in a closed vessel free from oxygen and be then run into another
vessel where it is charged with carbonic acid gas under pressure, in the same way
as is done with ordinary aerated waters, forming an aerated chalybeate water
which is then bottled off for use. The bottles employed should be of coloured
glass in order to prevent the action of the light on the iron in solution.
Dated this 9th day of February 1893.
ABEL & IMRAY,
Agents for the Applicants.
COMPLETE SPECIFICATION.
A Manufacture of Pharmaceutic Preparations, for Use more
particularly in Cases of Anemia and for Weak Throats.
We, WILLIAM WEBSTER F.C.S., of Glencot, Blackheath Park, Blackheath,
and THOMAS MOORE F.R.C.S., of Lee Terrace, Blackheath, both in the County
of Kent, do hereby declare the nature of this invention and in what manner the
same is to be performed to be particularly described and ascertained in and by
the following statement :-
Our invention has for its object a manufacture of pharmaceutical preparations
consisting mainly of aqueous solutions containing oxides and carbonates of iron, to
which is added a body such as glycerine which tends to partially neutralise the
astringent action which iron has upon the human system.
For this purpose we in the first place add to the water a small proportion of
common salt and we then subject it to electrolytic action by means of iron
electrodes immersed therein, thereby obtaining oxides and carbonates in solution,
the strength of the current employed being by preference not greater than

page_text: th ampère per square foot of surface of the electrodes employed, in order not to
cause waste of iron.
Either before or after the above described action we add to the water glycerine,
by preference in the proportion of about 40 minims to every ounce of water, such
admixture having the effect, both of retarding the oxidation of the neutral iron
salt in solution and of partially preventing the astringent action of the iron when
taken internally.
The above described préparation is applicable with very beneficial results in
cases of anemia and is also valuable as a gargle for weak throats.
This preparation may also be prepared in the first instance in an atmosphere of
carbonic acid in a closed vessel free from oxygen in which it is charged with
carbonic acid gas under pressure, in the same way as is done with ordinary
aerated waters forming an aerated chalybeate water, which vessel may be similar
_to_an ordinary seltzogene, or,-for-manufacture on a large scale, the fluid prepared in
an atmosphere of carbonic acid, may then be run into a separate vessel in which it
is charged with carbonic acid under pressure, and from which it is drawn off in
glass bottles. The bottles employed should be of coloured glass in order to
prevent the action of the light on the iron in solution.
When the fluid is prepared as above described in the presence of carbonic acid,
the addition of salt is not required.
The accompanying drawing shews a simple arrangement of apparatus, operating
as a seltzogene for producing the aerated chalybeate fluid, as above described.
The apparatus consists of a strong iron lower vessel A, to which is fixed a glass
upper vessel B; C is a cast iron tube fixed to the metal syphon head D, of ordinary
construction, and passing down into the vessel A. This tube C serves both for the
discharge of the aerated liquid in the ordinary manner of seltzogenes and also as
the one electrode of a small electric battery, the one pole of which is put in electric
connection therewith by connecting the wire to a screw terminal E fixed on the
metal head D, while the other pole of the battery is connected to the screw
terminal F fixed on the vessel A, which is thus made to constitute the other
electrode. The mode of operating with this apparatus is as follows.
The cap D with the tube C.having been unscrewed and removed, the vessel A. is
more or less filled with the fluid to be acted upon, and the usual ingredients for
generating carbonic acid gas are introduced into the vessel B round the tube G.
The tube C and cap D are, then replaced, the vessel is tilted so that the requisite
amount of water will pass from A through tube G into.vessel B, and the terminals E
and are connected with the battery, so as to set up electrolytic action in the
vessel A while at the same time the liquid is being charged with carbonic acid.
After a short time a sufficient electrolytic action will have been obtained to render
the liquid chalybeate, whereupon the battery is disconnected, and after the liquid
has absorbed a sufficient quantity, of carbonic acid, it is ready for use. It is
preferred to connect the battery in such manner that the iron is taken up from the
tube Cand not from the vessel A, as the tube C, being screwed into the head D,
can be readily removed and replaced by a new one when worn. The quantity of
iron taken up is however so small, that the tube will. remain serviceable for a long
time. I is an insulating plate.
In order to prevent. metallic contact between the tube C and the surrounding
tubular neck G of the vessel A, a ring H of insulating material may be fixed on
the tube C, having holes or notches for allowing the passage of the gas.
Having now particularly described and ascertained the nature of our said inven-
tion and in what manner the same is to be performed we declare that what we
claim is
1. The herein described process for the production of pharmaceutical préparations
wherein water is subjected to electrolytic action by means of iron electrodes
immersed therein, so as to obtain oxides and carbonates of iron in aqueous solution,
to which liquid glycerine or equivalent substance is added.

page_text: 2. A pharmaceutical preparation composed of an aqueous solution of oxides and
carbonates of iron produced by electrolytic action, and combined with glycerine or
equivalent substance substantially as described.
3. A manufacture of aerated chalybeate fluid by effecting the electrolytic action
on water referred to in the first claim within a closed vessel in the presence of
carbonic acid gas, substantially as described.
Dated this 8th day of November 1893.
ABEL & IMRAY,
Agents for Applicants.