The Manufacture of Improved Preparations of Iron for Medicinal Purposes.
Year: 1897

page_text: Date of Application, 15th Apr., 1897-Accepted, 10th July, 1897
COMPLETE SPECIFICATION.
The Manufacture of Improved Preparations of Iron for Medicinal
Purposes.
I, ERNST DOLLE, of 3 Wilhadistrasse, Bremen, in the German Empire, Apothecary,
do hereby declare the nature of this invention and in what manner the same is to
be performed to be particularly described and ascertained in and by the following
statement:
-
The present invention relates to the manufacture of preparations of iron for
medicinal purposes, which possess, with high efficacy, the great advantage that
they have lost the unpleasant flavour of iron and are accordingly readily taken by
invalids. This has the immediate result that iron preparations can be more
generally used than heretofore, and physicians will be provided with a remedy for
effectively treating chlorosis, from which probably the greater part of the female
population suffer.
The said invention relates more especially to a particularly effective iron-
preparation, iron-milk, which is made by precipitating a solution of chloride of iron
by means of phosphate of soda.
This iron-milk however, like all other iron preparations previously known,
possesses the unpleasant flavour of iron, and heretofore it has not been possible to
do away with this flavour which has made the general use of this otherwise
excellent remedy impossible.
The object of the present invention is to entirely remove the unpleasant iron-
flavour by treating or combining the iron-milk with certain substances, and to
produce an iron-preparation which is of very agreeable flavour, acts very favour-
ably on the stomach and brings the iron contained therein into action in the most
effective way. For this purpose I proceed as follows:-
After a dilute solution of chloride of iron has been treated with a solution of
phosphate of soda and the precipitate so produced washed several times with water
so as to remove the sodium chloride simultaneously formed, the preparation so
obtained is treated with suitable quantities of one or more of the substances
hereinafter mentioned, viz:-
Tincture of Cardamon;
Essence of Oranges;
Bishop's Extract (Essentia episcopalis);
Tincture of Vanilla;
Tincture of Ginger;
Aromatic tincture;
Tincture of Cinnamon;
Acetic Ether;
Vanillin:
Spirits of Wine;
Sugar-syrup.
These substances act on the iron-milk in such a manner as to entirely remove
the unpleasant iron-flavour from the iron-preparation, and a preparation is pro

page_text: duced which is not only of very agreeable flavour but also produces very favourable
effects on the invalid.
The proportion in which the iron-milk is mixed with the other substances is not
a fixed or rigid one; it can be varied according to requirement or desire. The
following has proved to be a very advantageous proportion, viz:—
Iron-Milk
Sugar Syrup
Spirits of Wine
Tincture of Vanilla
Aromatic tincture
Tincture of cinnamon
1000.0
120.0
80.0
5.0
1.5
1.0
0.5
0.1
Acetic ether
Vanillin
Moreover essence of oranges, Bishop's Extract, tincture of ginger, and tincture
of cardamon can also be added, according to taste.
Bishop's Extract is an extract of orange and lemon or citron peel with spirits of
wine and white wine, to which glycerine is added.
Having now particularly described and ascertained the nature of my said inven-
tion and in what manner the same is to be performed I declare that what
I claim is
The manufacture of iron-preparations which do not possess the unpleasant flavour
of iron and which in a high degree bring the iron contained therein into action,
characterized in that iron-milk, which is made by the precipitation of a solution of
chloride of iron by means of phosphate of soda, is treated or combined with one or
more of the following substances, namely, tincture of Cardamon, essence of
oranges, Bishop's extract, tincture of vanilla, tincture of ginger, aromatic tincture,
tincture of cinnamon, acetic ether, vanillin, spirits of wine or sugar-syrup,
substantially as hereinbefore described.
Dated this 15th day of in: 1007
D. YOUNG & CO.,
11 & 12 Southampton Buildings, London, W.C., Agents for the Applicant.