Improvements in Coatings for Therapeutical Purposes.
Year: 1891

page_text: Date of Application, 12th Jan., 1891
Complete Specification Left, 9th Oct., 1891-Accepted, 21st Nov., 1891
PROVISIONAL SPECIFICATION.
[Communicated from abroad by ICHTHYOL GESELLSCHAFT, CORDES, HERMANNI
& Co., of 21, Bohnenstrasse, Hamburgh, in the Empire of Germany, Manu-
facturers of Pharmaceutical Preparations.]
Improvements in Coatings for Therapeutical Purposes.
I, HENRY HARRIS LAKE, of the firm of Haseltine, Lake & Co., Patent
Agents, 45 Southampton Buildings, in the County of Middlesex do hereby
declare the nature of this invention to be as follows:-
This invention relates to an improved coating for therapeutical purposes, into
which the remedy is incorporated.
Heretofore such coating used in medicine as carriers for the remedy to be applied
to the injured part of the body either could not be washed off the latter, by water
or they caused by secondary action, irritations or inflammations.
The object of this invention is to avoid such inconveniences and to prepare a
hermetic covering, coating or carrier of the remedy, the ablution of which may be
easily effected.
To carry this invention into practice the remedy, in substance or in solution, is
thoroughly mixed with a corresponding portion of pure starch or amylum (not
paste) or substances containing starch or amylum.
In cases, where a simple addition of amylum or starch is not sufficient to keep
the said mass homogeneous, certain portions of albumen, caseine or other similar
acting substances have to be added.
In order to obtain a thoroughly mixed mass for a coating of the desired properties
the starch is preferably mixed with cold water in the proportion of about half of
its own weight, because starch or amylum will mix better with the remedy when
moistened.
'According to this invention, for instance, an Ichthyol-coating may be obtained
as follows: Pure wheat-starch is sprinkled with half of its weight of water and
thoroughly mixed with an equal weight of Ichthyol; 1 to 15 per cent. of a con-
centrated solution of albumen is then added whereupon the mixture is triturated
again until it has attained a homogeneous condition, in which it may be applied to
the injured part of the body.
When a coating having also antiseptical properties is to be prepared, in lieu of
albumen, caseine or the like, such antiseptic substances may be used, which, as for
instance carbolic acid, have the property to prevent the starch or amylum from
settling in the water.
101
LAMON1001
COMPLETE SPECIFICATION.
Improvements in Coatings for Therapeutical Purposes.
I, HENRY HARRIS LAKE of the firm of Haseltine, Lake & Co., Patent
Agents, 45 Southampton Buildings in the County of Middlesex, do hereby
declare the nature of this invention, and in what manner the same is to be
performed, to be particularly described and ascertained in and by the following
statement:-
This invention relates to an improved coating for therapeutical purposes into

page_text: Heretofore in the use of such coatings as carriers for the remedy to be applied
to the injured part of the body and which consist essentially of gelatine gum-arabic,
glue, dextrine, paste or collodium the said coatings have failed in their purpose in
all cases where it has been required to use hygroscopic remedies.
The object of this invention is to avoid such inconveniences and to prepare an
hermetic covering, coating or carrier for the remedy, the ablution of which may be
easily effected.
To carry this invention into practice the remedy, in substance or in solution, is
thoroughly mixed with a corresponding portion of pure starch or amylum (not
paste) or substances containing starch or amylum.
In cases, where a simple addition of amylum or starch is not sufficient to keep
the said mass homogenous certain portions of albumen, caseine or other similarly
acting substances should be added.
In order to obtain a thoroughly mixed mass for a coating of the desired properties
the starch is preferably mixed with cold water in the proportion of about half its
weight, as starch or amylum will mix better with the remedy when moistened.
According to this invention, for instance, an Ichthyol-coating may be obtained
as follows.
Pure wheat-starch if sprinkled with half its weight of water and thoroughly
mixed with an equal weight of Ichthyol; 1 to 1.5 per cent. of a concentrated solution
of albumen is then added whereupon the mixture is triturated again until it has
attained a homogeneous condition in which it may be applied to the injured part
of the body.
cent.
A glycerine coating is obtained by mixing in the same manner about 30 per cent.
of glycerine with 30 per cent. of starch-meal, 15 per cent. of water and 25 per
of gum-arabic or 40 per cent. of glycerine are mixed with 40 per cent. of starch-
meal and 20 per cent. of a concentrated solution of caseine to which, if necessary,
about 0.5 per cent. of carbolic acid may be added.
In the same way a chloride of calcium coating is prepared by mixing about
40 per cent. of a solution of chloride of calcium (containing 50 per cent. of the salt)
together with 40 per cent. of starch-meal, 10 per cent. of water and 10 per cent. of a
concentrated solution of albumen.
When a coating having also antiseptic properties is to be prepared, in lieu of
albumen, caseine or the like, such antiseptic substances may be used which, as for
instance carbolic acid, have the property of preventing the starch or amylum from
settling in the water.
A coating of such a nature may be obtained by mixing together 50 parts of
starch-meal, 22.5 parts of water, 2.5 parts of carbolic acid and 25 parts of
Ichthyol.
Having now particularly described and ascertained the nature of the said
invention, and in what manner the same is to be performed, as communicated to
me by my foreign correspondents, I declare that what I claim is :-
First. A medicinal preparation consisting of amylum or substances containing
amylum into which the remedy or remedies are incorporated, substantially as and
for the purpose set forth.
Second. In a medicinal preparation consisting of amylum or substance containing
amylum into which the remedy or remedies are incorporated, the addition of
albumen, caseine or other similar substances capable of keeping the amylum
suspended in the remedy or remedies when in a liquid condition, substantially as
and for the purpose set forth.
Third. In a medicinal preparation consisting of amylum or substances con-
taining amylum into which the remedy or remedies are incorporated, the addition
of carbolic acid or other antiseptic matter having the property of preventing the
amylum from settling in water, substantially as and for the purpose set forth.
Fourth. The method of depriving remedies of their hygroscopic properties and
to make the same applicable as a therapeutical coating, by adding to the remedy

page_text: or remedies or their aqueous solution certain quantities of starch or amylum or
substances containing amylum and a substance, such as albumen, caseine, carbolic
acid or other body capable of keeping the amylum suspended in the remedy or
remedies, substantially as set forth."
Dated this 9th dox of October 1901
HASELTINE, LAKE & Co.,
45, Southampton Buildings, London, Agents for the Applicant.