The Manufacture and Production of Preparations of Salicylic Acid suitable for Surgical Antiseptic Purposes.
Year: 1898

page_text: The Manufacture and Production of Preparations of Salicylic Acid
suitable for Surgical Antiseptic Purposes.
I, BENJAMIN WILLCOX, of 47, Lincoln's Inn Fields, in the County of London,
Patent Agent, do hereby declare the nature of this invention (which has been
communicated to me from abroad by Vereinigte Chininfabriken Zimmer & Co.,
Gesellschaft mit beschrankter Haftung, of Frankfort-on-Main, in the German
Empire) to be as follows:-
Although free salicylic acid is an efficient antiseptic it cannot be applied to
surgical purposes owing to its corrosive action and the hitherto known salts of
salicylic acid have not been capable of application to surgical purposes. either
because they are devoid of antiseptic properties, or on account of the poisonous
properties of the metal with which the salicylic acid is combined.
My foreign correspondents have succeeded in preparing salts of salicylic acid
which whilst presenting the strikingly antiseptic character of salicylic acid do not
possess the aforesaid disadvantages.
The salts prepared according to this invention are the hitherto unknown com-
pounds of salicylic acid with the rare earths, particularly didymium and lanthanum
earths. These salts are widely applicable in surgery, especially as dry antiseptics,
being distinguished from the compounds of this class which have been hitherto
used in that they contain no poisonous material no iodine and no heavy metals
and the like.
Antiseptic action to such a degree is not possessed either by the separate con-
stituents of the salts in question or by other salts of the rare earths.
Didymium or lanthanum salicylate, or a mixture of both salts, is best prepared
by adding the equivalent quantity of a salicylate (for example sodium salicylate)
to a solution of known strength of a soluble salt of the said earth or earths and
then filtering and washing the precipitate. The compounds can be also prepared
by direct action of salicylic acid on the hydrate or carbonate of the said earth or
earths.
Didymium salicylate is a pale pink powder insoluble in water.
The constitution is Di,(CH(OH).COO) Â·
6'
The Manufacture and Production of Preparations of Salicylic Acid
suitable for Surgical Antiseptic Purposes.
I, BENJAMIN WILLCOX, of 47, Lincoln's Inn Fields, in the County of London,
Patent Agent, do hereby declare the nature of this Invention (which has been
[Price 8d1

page_text: communicated to me from abroad by Vereinigte Chininfabriken Zimmer & Co.,
Gesellschaft mit beschrankter Haftung, of Frankfort-on-Main, in the German
Empire) and in what manner the same is to be performed to be particularly
described and ascertained in and by the following statement: ---
Although free salicylic acid is an efficient antiseptic it cannot be applied to
surgical purposes owing to its corrosive action and the hitherto known salts of
salicylic acid have not been capable of application to surgical purposes, either
because they are devoid of antiseptic properties, or on account of the poisonous
properties of the metal with which the salicylic acid is combined.
My foreign correspondents have succeeded in preparing salts of salicylic acid
which, whilst presenting the strikingly antiseptic character of salicylic acid do not
possess the aforesaid disadvantages.
The salts prepared according to this invention are the hitherto unknown com-
pounds of salicylic acid with the rare earths, particularly didymium and lanthanum
earths. These salts are widely applicable in surgery, especially as dry antiseptics,
being distinguished from the compounds of this class which have been hitherto
used, in that they contain no poisonous material, no iodine, and no heavy metals
and the like.
Antiseptic action to such a degree is not possessed either by the separate con-
stituents of the salts in question or by other salts of the rare earths.
Didymium or lanthanum salicylate, or a mixture of both salts, is best prepared
by adding the equivalent quantity of a salicylate (for example, sodium salicylate)
to a solution of known strength of a soluble salt of the said earth or earths and
then filtering and washing the precipitate. The compounds can be also prepared
by direct action of salicylic acid on the hydrate or carbonate of the said earth or
earths.
Didymium salicylate is a pale pink powder insoluble in water.
The constitution is Di̟(CH(OH).COO) 6.
Having now particularly described and ascertained the nature of the said In-
vention and in what manner the same is to be performed I declare that what
I claim is:-
1. The manufacture and production of preparations of salicylic acid suitable for
use as surgical antiseptics by acting on a soluble salt or soluble salts of the rare
earths and particularly of didymium and lanthanum with a salicylate.
2. The manufacture and production of preparations of salicylic acid suitable for
JOHNSONS & WILLCOX,
47, Lincoln's Inn Fields, London, W.C., Agents.