Improvements in the Manufacture of Auramine.
Year: 1893

page_text: Date of Application, 23rd Mar., 1893
Complete Specification Left, 21st Dec., 1893-Accepted, 27th Jan., 1894
PROVISIONAL SPECIFICATION.
Improvements in the Manufacture of Auramine.
I JAMES YATE JOHNSON of 47 Lincoln's Inn Fields in the County of
Middlesex Gentleman do hereby declare the nature of this invention (which has
been communicated to me from abroad by the Badische Anilin and Soda Fabrik
of Ludwigshafen on Rhine in the Empire of Germany) to be as follows:-
This application relates to improvements in and extensions of the inventions
claimed under Letters Patent Nos. 12,549 of 1889 and 16,666 of 1890.
In the Specifications of the said Letters Patent there is described the production
of auramine by treating tetra-methyl-diamido-diphenyl-methane, or its derivatives,
the corresponding hydrol and thio-hydrol, with sulphur and ammonia.
The present invention relates to the conversion of other derivatives of the said
methane compound into auramine dyes by treating them with sulphur and ammonia
under suitable conditions in each case.
Thus for instance auramine is obtained if tetra-methyl-diamido-diphenyl-mono-
methyl-methane or tetra-methyl-diamido-diphenyl-dimethyl-methane be treated in
this manner.
The said mono- and di-methyl-methane compounds can be obtained by the
condensation of aldehyde and acetone respectively with di-methyl-aniline and in
other ways (see Döbner Berichte der Deutschen Chemischen Gesellschaft 12, 813;
Hofmann and Martins, ibid. 6, 345). The analogues of these bodies can also be
employed for the purposes of this invention and analogous results are obtained.
The following example describes the application of the invention to the above
mentioned di-methyl-methane compound, but the details of the process may in some
cases be varied.. The parts are by weight..
Example. Melt together about fourteen parts of tetra-methyl-diamido-diphenyl-
dimethyl methane and about six parts of sulphur, in the presence of a suitable
diluent such as a mixture of about one hundred and twenty parts of common salt
and about seven parts of ammonium chloride: Pass a stream of ammonia gas
through the mixture for about eight hours maintaining the temperature of the
oil-bath at about one hundred and twenty five degrees centigrade.
After the reaction is: ended wash the melt in the form of powder with cold water
to dissolve out the common salt and ammonium chloride, then dissolve in water at
seventy degrees centigrade, filter from insoluble impurities, precipitate the dye with
common salt, filter, press and dry.
Dated this 02.d daw of March 1902
J. H. JOHNSON & Co.,
47, Lincoln's Inn Fields, London, W.C., Agents
COMPLETE SPECIFICATION.
Improvements in the Manufacture of Auramine.
I JAMES YATE JOHNSON of 47 Lincoln's Inn Fields, in the County of Middlesex
Gentleman do hereby declare the nature of this invention (which has been com-
municated to me from abroad by the Badische Anilin and Soda Fabrik of Ludwig-
shafen-on-Rhine in the Empire of, Germany) and in what manner the same is to

page_text: be performed to be particularly described and ascertained in and by the following
statement :-
This application relates to improvements in and extensions of the inventions
claimed under the Letters Patent Nos. 12,549 of 1889 and 16,666 of 1890.
In the Specifications of the said Letters Patents there is described the production
of auramine by treating tetra-methyl-diamido-diphenyl-methane, or its derivatives,
the corresponding hydrol and thio-hydrol, with sulphur and ammonia.
The present invention relates to the conversion of another derivative of the said
methane compound viz., tetra-methyl-diamido-diphenyl-dimethyl-methane into
auramine by treating it with sulphur and ammonia under suitable conditions.
The said dimethyl-methane compound can be obtained by the condensation of
acetone with dimethyl aniline and in other ways (see Döbner, Berichte der
Deutschen Chemischen Gesellschaft, 12, 813; Hofmann and Martins ibid. 6, 345).
The following example describes the manner in which the invention can be
carried into practical effect; but the details of the process may be varied without
departing from the nature of the invention. The parts are by weight.
Example. Melt together about fourteen parts of tetra-methyl-diamido-diphenyl-
dimethyl-methane and about six parts of sulphur, in the presence of a suitable
diluent such as a mixture of about one hundred and twenty parts of common salt and
about seven parts of ammonium chloride. Pass a stream of ammonia gas through
the mixture for about eight hours, maintaining the temperature of the oil-bath at
about one hundred and seventy five degrees centigrade.
After the reaction is ended wash the melt in the form of powder with cold water
to dissolve out the common salt and ammonium chloride, then dissolve in water at
seventy degrees centigrade filter from insoluble impurities, precipitate the dye with
common salt, filter, press and dry.
Having now particularly described and ascertained the nature of the said inven-
tion and in what manner the same is to be performed I declare that what I
claim is :-
:-
The manufacture of auramine by treating tetra-methyl-diamido-diphenyl-
dimethyl-methane with sulphur and ammonia substantially in the manner herein-
before described.
Dated this 19th day of December 1893.
J. H. JOHNSON & Co.,
Agents.