Production of Methylglyoxalidine CHÂN2.
Year: 1894

page_text: Date of Application, 30th July, 1894
Complete Specification Left, 39th Apr., 1895-Accepted, 1st June, 1895
PROVISIONAL SPECIFICATION.
[Communicated from abroad by THE FARBWERKE, vormals MEISTER LUCIUS-
AND BRUNING of Hoechst a/ Main, in the Empire of Germany, Chemical -
Manufacturers.]
Production of Methylglyoxalidine CHÂN₂.
2.
I, OLIVER IMRAY, of No. 28, Southampton Buildings, Chancery Lane, in the
County of London, Chartered Patent Agent, do hereby declare the nature of this
invention to be as follows:-
The base methylglyoxalidine C.HN, is produced by dry distillation of hydro-
chlorate of ethylendiamine with sodium acetate as, for example in the following
manner.
270 grs. of hydrochlorate of ethylendiamine are carefully mixed with 350 grs..
The distillate
of dehydrated sodium acetate, and the mixture is distilled off.
passing over from 190° to 220° C. contains methylgylyoxalidine besides ethylendi-
amine.
Pure methylglyoxalidine can be obtained in several ways, for example, by means
of its hydrochlorate, which is much more easily soluble in alcohol than the ethylendi-
amine hydrochlorate.
The methylglyoxalidine is separated from its hydrochlorate by alkalies, taken up
in chloroform and dried by potassium carbonate. The base melts at 105° C., its
boiling point is 198° C., it is easily soluble in alcohol, acetone and chloroform,
almost unsoluble in ether.
The base is identical with that prepared by A. W. Hofmann (Ber. 21. 2332) by
heating diacetylethylendiamine.
His observations essentially differ from the above but this is to be explained by
the insufficient purity of Hofmann's base.
By employment of sodium propionate and higher homologues instead of sodium
acetato similar bases are obtained.
Dated this 30th day of July 1894.
ADEL & IMRAY,
Agents for the Applicant.
COMPLETE SPECIFICATION.
Production of Methylglyoxalidine CH,N.
I, OLIVER IMRAY of No. 28 Southampton Buildings, Chancery Lane, in the
County of London, Chartered Patent Agent, do hereby declare the nature of this
invention and in what manner the same is to be performed to be particularly
described and ascertained in and by the following statement :-
The base methylglyoxalidine C.HN, is produced by dry distillation of hydro-
chlorate of ethylendiamine with sodium acetate, as, for example, in the following
manner.
270 grs. of hydrochlorate of ethylendiamine are carefully mixed with 350 grs.
of dehydrated sodium acetate, and the mixture is distilled off.
The distillate

page_text: passing over at from 100° to 220° C. contains methylglyoxalidine besides ethylendi-
amine.
Pure methylglyoxalidine can be obtained in several ways, for example, by means
of its hydrochlorate, which is much more easily soluble in alcohol than the
ethylendiamine hyrochlorate.
The methylglyoxalidine is separated from its hydrochlorate by alkalies, takon up
in chloroform and dried-by potassium carbonate. The base melts at 105° C., its
boiling point is 198° G., it is easily soluble in alcohol, acetone and chloroform,
almost insoluble in ether.
The base is identical with that prepared by A. W. Hofmann (Ber. 21. 2332)
by heating diacetylethylendiamine.
His observations essentially differ from the above, but this to be explained by
the insufficient purity of Hofmann's base.
By employment of sodium propionate and higher homologues instead of sodium
acetate, similar bases are obtained.
Having now particularly described and ascertained the nature of this inven-
tion and in what manner the same is to be performed I declare that what
I claim is :-
Production of methylglyoxalidine and its homologues by distilling hydrochlorate
of ethylendiamine with sodium acetate or its homologues.
Dated this 30th day of April 1895.
ABEL & IMRAY,
Agents for the Applicant.