Process for the Preparation of a Remedy for Neurasthenia and Epilepsy.
Year: 1896

page_text: Date of Application, 20th Jan., 1896-Accepted, 25th Apr., 1896
COMPLETE SPECIFICATION.
Process for the Preparation of a Remedy for Neurasthenia and
Epilepsy.
I, Dr. GEORG DIETTRICH, of Via Giulio, 7, Turin, in the Kingdom of Italy,
Physician do hereby declare the nature of this invention and in what manner the
same is to be performed, to be particularly described and ascertained in and by
the following statement :-
The present invention provides an effective remedy for neurasthenia and epilepsy.
The object in view is attained by treating the fluid expressed from prepared bull
testicles with osmic acid and separating the liquid from the precipitate after
standing for a certain time. The preparation of the testicles is preferably as
follows: The same are freed from their envelope (tunica) washed, soaked, and
treated with glycerine. The separation of the precipitate caused by the osmic acid
is effected by filtering the fluid through a cotton wool filter soaked with alcohol.
In order finally to prepare the fluid in a form suitable for injections, the fluid
mixed with water is pressed through an aluminium or porcelain filter.
The process may be carried out practically as follows, by way of example.
The fresh testicles of a healthy bull, slaughtered not more than five hours
previously at most, are removed from their envelope (tunica) washed in distilled
water and cut into pieces about 3 cm. long & 1 cm. thick care being taken, that no
blood remains in them.
After the whole is macerated (whereby certain substances are extracted) it is
placed in distilled water, and after 5 minutes placed in a tin plate vessel without
water and half its weight of pure glycerine added. A pressure sieve is then
placed upon the mass, and after 14 hours the resultant fluid is filtered through thick
filter paper.
To every 100 grammes of the resulting fluid nine drops of a 1% solution of
osmic acid is added, the whole shaken up, and allowed to stand.
After from 3 to 4 hours the fluid assumes a dark brown, almost black colour, and
after 5 hours the same is twice filtered through a cotton wool filter soaked with
absolute alcohol, the first drops, which contain much alcohol being rejected. To
the fluid is added one third of distilled water, and the whole is finally filtered
through an aluminium bougie (tube) at a pressure of 15 atmospheres.
Having now particularly described and ascertained the nature of my said inven-
tion, and in what manner the same is to be performed, I declare that what I
claim is :-
1. A process for the preparation of a remedy for neurasthenia and epilepsy
characterised by treating the fluid pressed out of prepared bull testicles with osmic
acid and the separation of the fluid from the precipitate after allowing it to stand
some time.
2. In the process set forth in Claim 1 the preparing of the bull testicles by
removing therefrom the envelope (tunica) washing, soaking, and treating with
glycerine.
3. In the process set forth in Claims 1 and 2 the separation of the precipitate
caused by the addition of osmic acid by filtering the liquid through a cotton wool
filter soaked in alcohol.
4. In the process set forth in Claims 1 to 3 the preparation of the liquid

page_text: obtained in a form suitable for injections, by pressing the liquid mixed with water
through an aluminium or porcelain filter.
Dated this 20th day of January 1896.
W. P. THOMPSON & Co.,
31 High Holborn, London, W.C., Patent Agents for the Applicant.