Improvements in the Manufacture of a Light Colored Albumen from Blood.
Year: 1892

page_text: Date of Application, 17th Feb., 1892
Complete Specification Left, 16th Nov., 1892-Accepted, 4th Feb., 1893
PROVISIONAL SPECIFICATION.
Improvements in the Manufacture of a Light Colored Albumen
from Blood.
I, Dr. CARL COSINERU of No. Schlegelstrasse Berlin in the Empire of
Germany do hereby declare the nature of this invention to be as follows:-
This invention relates to the manufacture of a light colored albumen from blood
or a portion of blood liquor for instance the reddish serum or the portion which is
rich in blood corpuscles.
For this purpose the defibrinated blood is mixed with methylic or ethylic alcohol
or acetone or a mixture of either which contains small quantities of an acid.
The albumen and globuline, which the blood contains are hereby precipitated
while the essential colouring matter, the haematine is dissolved and can be separated
by a repeated extraction or decantation. The alcohol or acetone still adhering to
the albumen is thrown off by washing with water or by distillation and by the use
of oxidyzing agents the albumen may be bleached. The light coloured albumen
resulting may then be used for many purposes for which the ordinary brownish-
black product is not suitable.
The haematiue can be extracted from the solution in the usual manner.
En day of February 20
DR. CARL COSINERU,
By Harris & Mills,
23, Southampton Buildings, London, W.C., Agents.
COMPLETE SPECIFICATION..
Improvements in the Manufacture of a Light Colored Albumen
from Blood.
I, Dr. CARL COSINERU, of No. 8 Schlegelstrasse, Berlin, in the Empire of
Germany, do hereby declare the nature of this invention, and in what manner the
same is to be performed, to be particularly described and ascertained in and by the
following statement :-
This invention relates to the manufacture of a light coloured albumen from blood
or the constituents of the blood liquor, such as, for instance, the portion which is
rich in blood globules or corpuscles.
The process for the production of such light coloured albumen is based on my
observation that by mixing defibrinized blood with slightly acidulated ethyl
alcohol, methyl alcohol, acetone, or a mixture of these liquors, the albumen and
globuline contained in the blood are precipitated, whilst the colouring matter of
the blood, hæmatine, remains in solution.
The quantity of alcohol or acetone to be employed depends on the quantity of
water contained in the blood. I have found by experience that in order to obtain
good results the mixture, after the addition of the blood, ought not to contain more
than 20 per cent. of water.
The acids employed are the well known acids; I find by using sulphuric acid or
phosphoric acid I obtain a very good result.
The following example will clearly show the manner in which my invention may
be carried into effect.
One part of defibrinized blood is introduced in a thin jet into four or five parts
of ethyl alcohol of 95 per cent. previously acidulated by means of 1 per cent.
sulphuric acid. The mixture is well stirred during the addition of the blood; the

page_text: albumen separates in the form of almost colourless flakes; the red brown coloured
mother-liquors are separated from the albumen by filtration and washing with
alcohol and finally with water.
The product obtained in this way may moreover, if necessary, be bleached by
treating the same with oxydizing agents, such, for instance, as hydrogen dioxyde.
I'may also proceed in the following way; I may mix the blood or its constituents
at first with neutral alcohol or' acetone and then add the acid, or I may mix the
blood, slightly acidulated, with alcohol or acetone, the result remaining in all these
cases the same.
The albumen obtained according to the before described process is, with regard
to its purity and light color, adapted for numerous industrial purposes, and is
moreover an extremely valuable alimentary substance.
. Having now particularly described and ascertained the nature of my said inven-
tion, and in what manner the same is to be performed I declare that what I
claim is :-
1. The process for the production of light coloured albumen from blood or its
constituents, by mixing the latter with slightly acidulated ethyl alcohol, methyl
alcohol, acetone or a mixture of these liquors, and separating the albumen pre-
cipitated in this way from the coloured mother-liquors by filtration or any other.
suitable mechanical process.
2. The production of light coloured albumen from blood by the process substan-
tially as herein described.
101 1
Dated this 10th day of November 1892.
DR. CARL COSINERU,
By Harris & Mills,
23, Southampton Buildings, London, W.C., Agents.