Manufacture of Caffeine-sulphonates.
Year: 1893

page_text: Date of Application, 8th Sept., 1893
Complete Specification Left, 7th June, 1894- Accepted, 7th July, 1894
PROVISIONAL SPECIFICATION.
[Communicated from abroad by THE FARBWERKE vormals MEISTER LUCIUS
AND BRUNING, of Hoechst a/Main, in the Empire of Germany, Manufacturers.]
Manufacture of Caffeine-sulphonates.
I, OLIVER IMRAY, of No. 28, Southampton Buildings, Chancery Lane, in the
County of London, Chartered Patent Agent, do hereby declare the nature of this
invention to be as follows:-
:-
My correspondents have discovered that when an aqueous solution of neutral
sulphites, such as for example sulphite of sodium, is heated with bromo-caffeine or
better still with chloro-caffeïne salts of the caffeine-sulphonic acid are obtained.
The chloro-caffeine can be easily produced in following the directions given by
E. Fischer in the paper published in the Annalen 221 p. 336.
Example: 100 parts of chloro-caffeine
75
."
"
NaSO, (anhydrous)
are dissolved in 1,000 parts of water and heated for some time in a vessel furnished
with a reflux cooler or more advantageously in a digester at about 150° C. for
about 8 hours.
The caffeine-sulphonate of sodium which on cooling separates almost entirely, is
drawn off and whatever portion may have remained in solution is recovered by
evaporating or by precipitating it by means of common salt.
In order to further purify the caffeine-sulphonate of sodium, it is dissolved in
hot water, the filtered solution is evaporated to a large extent, the salt which on
cooling separates is freed from the mother-lye by drawing off and is boiled in
alcohol and dried.
The caffeine sulphonate of sodium presents itself in the form of a white powder,
easily soluble in water, but insoluble in alcohol.
The aqueous solution is rendered somewhat turbid by the addition of chloride of
barium and acetate of lead (traces of sulphate of sodium and chloride of sodium);
the addition of acetate of copper does not produce precipitation.
Dated this 8th day of September 1893.
ABEL & IMRAY,
Agents for the Applicant.
COMPLETE SPECIFICATION.
Manufacture of Caffeïne-sulphonates.
I, OLIVER IMRAY, of No. 28, Southampton Buildings, Chancery Lane, in the
County of London, Chartered Patent Agent, do hereby declare the nature of this
invention and in what manner the same is to be performed, to be particularly
described and ascertained in and by the following statement :-
My correspondents have discovered that when an aqueous solution of neutral
sulphites, such as for example sulphite of sodium, is heated with bromo-caffeine or
better still with chloro-caffeine salts of the caffeine-sulphonic acid are obtained.
Price 8d1

page_text: The chloro-caffeine can be easily produced in following the directions given by
E. Fischer in the paper published in the Annalen 221 p. 336.
Example: 100 parts of chloro-caffeine
75
"
"9
NaSO, (anhydrous)
are dissolved in 1,000 parts of water and heated for some time in a vessel furnished
with a reflux cooler or more advantageously in a digester at about 150° C. for
about 8 hours.
The caffeine-sulphonate of sodium which on cooling separates almost entirely, is
drawn off and whatever portion may have remained in solution is recovered by
evaporating or by precipitating it by means of common salt.
In order to further purify the caffeine-sulphonate of sodium, it is dissolved in hot
water, the filtered solution is evaporated to a large extent, the salt which on
cooling separates, is freed from the mother-lye by drawing off and is boiled in
alcohol and dried.
The caffeine sulphonate of sodium presents itself in the form of a white powder,
easily soluble in water, but insoluble in alcohol.
The aqueous solution is rendered somewhat turbid by the addition of chloride of
barium and acetate of lead (traces of sulphate of sodium and chloride of sodium);
the addition of acetate of copper does not produce precipitation.
Having now particularly described and ascertained the nature of this inven-
tion and in what manner the same is to be performed, I declare that what I
claim.is :-
1. The production of caffeine-sulphonates by heating chloro- or bromo-caffeine
with an aqueous solution of soluble neutral sulphites.
2. The caffeine-sulphonates produced as set forth in the preceding claim.
Dated this 7th day of June 1801
ABEL & IMRAY,
'Agents for the Applicant.