A MEDICINE, ENTIRELY NEW, AND NOT HITHERTO PRACTICED, FOR THE SAFE, EXPEDITIOUS, AND EFFECTUAL CURING OF THE VENEREAL DISEASE, AND WHICH INVENTION I HAD, WITH GREAT LABOUR INDUSTRY, REPEATED EXPERIENCE, AND AT A CONSIDERABLE EXPENCE, BROUGHT TO SUCH A PERFECTION AS TO BE OF GENERAL UTILITY AND BENEFIT TO THE SUBJECTS OF THIS KINGDOM, AS NO PROPHYLACTICK REMEDY (BY WHICH TERM I MEAN THE ESSENTIA POLYCHRESTA, GOUTES DE PERU, OR THE FAMOUS ANTIVENEREAL PERU DROPS, WHICH ARE INCONTESTABLY THE ONLY ABSOLUTE SPECIFICK EVER KN OR OFFERED TO THE PUBLICK FOR THE SAFE,OUS, AND EECTUAL CURING IN BOTH SEXES THE SEVERAL SPECIES AND SYMPTONS OF THE VENEREAL DISEASE, NAMELY, THE ENDEMIAL MALADY OF PERU, A CLAP, OR VIRULENT GONORRHOEA, THE YAWES, NOW FREQUENT AND MALIGNANT, THE PLICA POLONICA, AND A CONFIRMED LUES OR Pox, WITH ALL
Year: 1758

page_text: TO ALL TO WHOM THESE PRESENTS SHALL COME, I, JOHN RYAN,
of the Parish of Saint Andrew, Holborn, in the City of London, Physician
and Surgeon, send greeting.
WHEREAS His present most Excellent Majesty King George the Second,
by His Letters Patent under the Great Seal of Great Britain, bearing date the
Sixteenth day of August, in the thirty-second year of His reign, reciting
that I, the said John Ryan, had, by my Petition, humbly represented unto
His Majesty that I was the sole Inventor of "A MEDICINE, ENTIRELY NEW, AND
NOT HITHERTO PRACTICED, FOR THE SAFE, EXPEDITIOUS, AND EFFECTUAL CURING
OF THE VENEREAL DISEASE, AND WHICH INVENTION I HAD, WITH GREAT LABOUR
INDUSTRY, REPEATED EXPERIENCE, AND AT A CONSIDERABLE EXPENCE, BROUGHT TO
SUCH A PERFECTION AS TO BE OF GENERAL UTILITY AND BENEFIT TO THE SUBJECTS
OF THIS KINGDOM, AS NO PROPHYLACTICK REMEDY (BY WHICH TERM I MEAN THE
ESSENTIA POLYCHRESTA, GOUTES DE PERU, OR THE FAMOUS ANTIVENEREAL PERU
DROPS, WHICH ARE INCONTESTABLY THE ONLY ABSOLUTE SPECIFICK EVER KNOWN OR
OFFERED TO THE PUBLICK FOR THE SAFE, EXPEDITIOUS, AND EFFECTUAL CURING IN
BOTH SEXES THE SEVERAL SPECIES AND SYMPTONS OF THE VENEREAL DISEASE,
NAMELY, THE ENDEMIAL MALADY OF PERU, A CLAP, OR VIRULENT GONORRHOEA, THE
YAWES, NOW FREQUENT AND MALIGNANT, THE PLICA POLONICA, AND A CONFIRMED
LUES OR Pox, WITH ALL ITS DEPLORABLE SYMPTOMS, AND THE SAID PERU DROPS ARE
ALSO, BY THEIR DETERSIVE AND ANTICEPTICK VIRTUE AN EFFECTUAL REMEDY FOR
STUBBORN GLEETS, SEMINAL WEAKNESSES AND INABILITIES, FOR THE VENEREAL
PILES, EITHER INTERNAL OR EXTERNAL, AND FISTULOUS DISORDERS. AND ARE A
CERTAIN PURIFIER OF THE BLOOD IN ALL SCORBUTICK HUMOURS, CANCEROUS, LEPROus,

page_text: AND SCROPHULOUS CASES, THEY ARE LIKEWISE A SOVEREIGN ANTIDOTE FOR THE
VENEREAL GOUT, RHEUMATISM, AND SCURVY, POPULAR DISEASES, YET COMMONLY
TAKEN FOR CONSTITUTIONAL DISORDERS, AS THEY ARE A SINGULAR SPECIFICK FOR EVERY
SPECIES OF FITS, PALPITATIONS, COMPLICATED, NERVEOUS, APOPLECTICK, EPILEPTICK,
AND PARALYTIC DISORDERS PROCEEDING FROM A VENEREAL CAUSE, AND ARE A
PROPHILACTICE REMEDY, OR AN ADMIRABLE PRESERVATIVE AGAINST CONTRACTING THE
VENEREAL INFECTION, THAT THE SAID PERU DROPS ARE PERFECTLY INNOCENT, DEVOID
OF ALL MERCURIALS, AND, BY THEIR BENIGN VIRTUE, OPERATE IN A MILD AND
FRIENDLY MANNER, ERADICATEING THE VIRULENCY OF THE DISEASE BY STOOL, URINE,
AND PERSPIRATION), OR THOROUGH METHOD HAS BEEN HITHERTO ADAPTED FOR THE
RADICAL CURE OF THE SAID DISEASE IN ITS PRESENT COMPLICATED STATE OF
MALIGNANCY" and praying His Majesty's Letters Patent for the sole use thereof,
His said Majesty did thereby give and grant unto me, the said John Ryan,
my executors, administrators, and assigns, His especial licence, sole priviledge
and authority, that I, the said John Ryan, my executors, administrators, and
assigus, and no other, should and lawfully might make, use, exercise, and vend
my said Invention, within England, Wales, and Berwick-upon-Tweed, for and
during the term of fourteen years from the date of the said recited Letters
Patent; in which said Letters Patent is contained a proviso that if I, the said
John Ryan, should not particularly describe and ascertain the nature of my
said Invention, and in what manner the same is to be performed, by an
instrument in writing under my hand and seal, and cause the same to be
inrolled in His said Majesty's High Court of Chancery within three calendar
months next after the date of the said Letters Patent, that then the said Letters
Patent, and all priviledges and advantages thereby granted, should utterly
cease, determine, and become void, as by the said Letters Patent, relation being
thereunto, may more fully and at large appear.
NOW KNOW YE, that I, the said John Ryan, in compliance with the said
proviso, do hereby further describe and particularly ascertain the nature of
my said Invention, and the ingredients whereof the same is to be composed,
as follows (that is to say):-
R. Salis cujusvis alkalini fixi, antimonii crudi, spiritus vini rectificati
a. a. q. s. ut fiat tinctura antimonium in pulverem redactum, sali admisce, et
igne forti liquescant simul per horam, deinde effunde, in pulverem redige, et
spiritu affuso, adde pulverem jalapii et bezoartum minerale secundum artem,
digere moderato, igne per duodecem dies ad extremum cola.
R. Lignorum guaiaci, sassafras, baccarum juniperi opii, salis tartari
a. a. q. s., ligna et opium incidantur, digere moderato, igne per totidem dies ut
superius.

page_text: R. Bals. Peru, capiv., tolut. Giliad, gum guaiac. pulv. jalap. rhei. sal. tart.
p. vin. rectif. a. a. q. s. digere pariter moderato calore per duodecem dies.
Omnia simul misce et serventur ad usum.
In witness whereof, I, the said John Ryan, have hereunto set my hand
and seal, the Thirteenth day of November, in the thirty-second year of
the reign of His Majesty King George the Second, and in the year of
our Lord One thousand seven hundred and fifty-eight.
Inrolled the Thirteenth day of November, in the thirty-second year of the
reign of His Majesty King George the Second, 1758.