Abstract:
An electronic system activatable by electrical power is described. The system is useful for influencing cellular functions or malfunctions in a warm-blooded mammalian subject. The system includes one or more controllable low energy HF (High Frequency) carrier signal generator circuits, one or more data processors for receiving control information, one or more amplitude modulation control generators and one or more amplitude modulation frequency control generators. The amplitude modulation frequency control generators are adapted to accurately control the frequency of the amplitude modulations to within an accuracy of at least 1000 ppm, most preferably to within about 1 ppm, relative to one or more determined or predetermined reference amplitude modulation frequencies.

Description:
FIELD OF THE INVENTION 
       [0001]    This invention relates to an electronic system for influencing cellular functions in a warm-blooded mammalian subject. More particularly, the invention concerns research findings related to how earlier electronic systems may be modified and programmed to achieve both improved and additional therapeutic effects. 
       BACKGROUND OF THE INVENTION 
       [0002]    Reference is made to European Patent EP 0 592 851 B1 and corresponding Patents and Patent Applications and to the various publications referred to therein. Since the time of the priority Application filed in the USA on 25 Sep. 1992 (U.S. Ser. No 951,563 now U.S. Pat. No. 5,441,528), a number of further publications related to effects of very low energy electromagnetic fields on patients suffering from insomnia and/or anxiety disorders have taken place:
   Koziol J A, Erman M, Pasche B, Hajdukovic R, Mitler MM (1993) Assessing a changepoint in a sequence of repeated measurements with application to a low-energy emission therapy sleep study.  J Applied Statistics  20: 393-400   Amato D, Pasche B (1993) An evaluation of the safety of low energy emission therapy.  Compr Ther  19: 242-247   Higgs L, Reite M, Barbault A, Lebet J P, Rossel C, Amato D, Dafni U, Pasche B (1994) Subjective and Objective Relaxation Effects of Low Energy Emission Therapy.  Stress Medicine  10: 5-13   Reite M, Higgs L, Lebet J P, Barbault A, Rossel C, Kuster N, Dafni U, Amato D, Pasche B (1994) Sleep Inducing Effect of Low Energy Emission Therapy.  Bioelectromagnetics  15: 67-75   Lebet J P, Barbault A, Rossel C, Tomic Z, Reite M, Higgs L, Dafni U, Amato D, Pasche B (1996) Electroencephalographic changes following low energy emission therapy.  Ann Biomed Eng  24: 424-429   Pasche B, Erman M, Hayduk R, Mitler M, Reite M, Higgs L, Dafni U, Amato D, Rossel C, Kuster N, Barbault A, Lebet J-P (1996) Effects of Low Energy Emission Therapy in chronic psychophysiological insomnia.  Sleep  19: 327-336   Kelly T L, Kripke D F, Hayduk R, Ryman D, Pasche B, Barbault A (1997) Bright light and LEET effects on circadian rhythms, sleep and cognitive performance.  Stress Medicine  13: 251-258   Pasche B, Barbault A (2003) Low-Energy Emission Therapy: Current Status and Future Directions. In  Bioelectromagnetic Medicine , Rosch P J, Markov M S (eds) pp 321-327. Marcel Dekker, Inc.: New York, N.Y.   
 
         [0011]    The above publications are related to an earlier device, system and use thereof described in said EP 0 592 851 B1. The improved electronic system and programmed control thereof in accordance with the present invention, however, has been determined to find therapeutic application not only for influencing cellular functions (or malfunctions) leading to central nervous system (CNS) disorders, but more particularly for influencing other cellular functions (or malfunctions) including directly or indirectly influencing cancerous cell growth or proliferation thereof in warm-blooded mammalian subjects. The direct or indirect influence on cancerous cell growth may involve but is not necessarily limited to any of prophylactic avoidance of cancerous cell formation, influencing of cell functions such as for example influencing leukocyte cell functions which can lead to inhibition of cancerous cell growth or proliferation thereof, and/or killing of cancerous cells harboured by a warm-blooded mammalian subject. 
         [0012]    Electromagnetic energy generating devices and use of electromagnetic energies for treating living mammalian subjects harbouring cancerous cells described in the literature include: U.S. Pat. No. 5,908,441 issued Jun. 1, 1999 to Bare; James E. and the references cited therein and so-called “NovoCure technology” involving in vivo implantation of electrodes to either side of tumorous growths. This literature however does not contemplate very low energy emissions of electromagnetic energy involving amplitude-modulated high frequency carrier signals as required in terms of the present invention. 
         [0013]    U.S. Pat. No. 5,690,692 issued on Nov. 25, 1997 entitled “Bio-Active Frequency Generator and Method” describes a programmable control which instructs a frequency synthesizer to enable generation of an electrical current at a specific precise frequency signal or at a series of specific precise frequencies signals having a square wave form to within an accuracy of 0.001 Hz. This Patent contemplates amplifying the voltage of the generated signals and applying the signals to a subject at the specific precise frequency or sequentially at the series of specific precise frequencies by means of electrodes held by or otherwise connected to the subject (which may be a mammal or a food). Once again, this Patent does not contemplate very low energy emissions involving amplitude-modulated high frequency carrier signals as required in terms of the present invention. 
       SUMMARY OF THE INVENTION 
       [0014]    In one aspect of the invention, an electronic system is provided which is activatable by electrical power. The system is employed to influence cellular functions or malfunctions in a warm-blooded mammalian subject. The system comprises one or more controllable low energy electromagnetic energy generator circuits for generating one or more high frequency radio frequency RF carrier signals. One or more microprocessors or integrated circuits comprising or communicating with the one or more generator circuits are provided which are also for receiving control information from a source of programmed control information. The one or more generator circuits include one or more amplitude modulation control signal generators for controlling amplitude modulated variations of the one or more high frequency carrier signals. The one or more generator circuits furthermore include one or more programmable amplitude modulation frequency control signal generators for controlling the frequency at which the amplitude modulations are generated. The one or more amplitude modulation frequency control generators are, in terms of an important improvement of the present invention, adapted to accurately control the frequency of the amplitude modulations to within an accuracy of at least 1000 ppm relative to one or more determined or predetermined reference amplitude modulation frequencies selected from within a range of 0.01 Hz to 150 kHz. The system furthermore comprises a connection or coupling position for connection or coupling to or being connected or coupled to an electrically conductive applicator for applying to the warm-blooded mammalian subject the one or more amplitude-modulated low energy emissions at said accurately controlled modulation frequencies. 
         [0015]    As used herein, the term, “accurately controlled” means that the modulated low energy electromagnetic emissions should be modulated to within a resolution of at most about 1 Hz of intended higher frequencies (greater than about 1000 Hz) determined or predetermined modulation frequencies. For example, if one of the one or more determined or predetermined modulation frequencies to be applied to the warm-blooded mammalian subject is about 2000 Hz, the accurate control should lead to such modulated low energy emission being generated at a frequency of between about 1999 and about 2001 Hz. However, and in terms of what has been determined from experiences in treating human subjects harbouring cancerous cells with the aim of arresting proliferation or killing of such cells, it is preferable that the accurate control should lead to a resolution of about 0.5, more preferably about 0.1, yet more preferably about 0.01 and indeed most preferably about 0.001 Hz of the intended determined or predetermined modulation frequency. 
         [0016]    Of importance is the requirement for emissions to be at a very low and safe energy level and result in low levels of absorption, the reason believed to be that physiological exchanges or flow of electrical impulses within warm-blooded animals (which are to be affected by application of the emissions of the present invention) are similarly at very low energy levels. In any event, in the region (at or near to the position of contact or close-by induction of the electrically conductive applicator with a subject receiving treatment), the specific absorption rate (SAR) should be and is most preferably substantially less than 1.6 milliW/g weight of living tissue. 
         [0017]    Furthermore of importance to achieve the intended biological therapeutic effect is that the stability of the emissions be maintained during emission, and that such stability should preferably be of the order of 10 −5 , more preferably 10 −6 , and most preferably 10 −7 , stability being determined as the relative deviation of frequency divided by the desired frequency, e.g. 0.01 Hz (deviation)/1,000 Hz (desired freq.)=10 −5 . 
         [0018]    As already described in said EP 0 592 851 B1, the system includes a microprocessor (which may more recently be replaced by an integrated circuit) into which control information is loaded from an application storage device. The microprocessor (or now alternatively integrated circuit) then controls the function of the system to produce the desired therapeutic emissions. Also described is the provision in the system of an impedance transformer connected intermediate the emitter of low energy electromagnetic emissions and a probe (here more broadly described as an electrically conductive applicator) for applying the emissions to the patient. The impedance transformer substantially matches the impedance of the patient seen from the emitter circuit with the impedance of the output of the emitter circuit. 
     
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
         [0019]      FIG. 1  shows an exemplary casing structure for the electronic circuit shown in  FIG. 2 , an applicator  13  (exemplified as a probe suitable for being placed in the mouth of a patient) and an interface  16  (which may be replaced by a receiver) for receiving information from a source of information  52  such as may be comprised in an information storage device, e.g. of the nature described and illustrated in FIGS. 12 to 17 of EP 0 592 851 B1. 
           [0020]      FIG. 2  is a block diagram of exemplary circuitry which may be comprised in the exemplary casing structure of  FIG. 1 . This  FIG. 2  differs essentially from FIG. 2 of EP 0 592 851 B1 by comprising a highly accurate modulation frequency generator  31  (named a Digital Direct Synthesizer or DDS), which enables accurate control of modulatable oscillator represented by dotted line block  106 . 
       
    
    
       [0021]    Reference is made to the various Figures of EP 0 592 851 B1 and the detailed description thereof, a number of which are exemplary of components which may be comprised in the circuit of  FIG. 2 . 
         [0022]    Thus, FIG. 3 of EP 0 592 851 B1 is a detailed schematic of a modulation signal generator 31, replaced by a DDS modulation frequency generator  31  comprised in the circuit of present  FIG. 2 ; 
         [0023]    FIG. 4 of EP 0 592 851 B1 is a detailed schematic of a modulation signal buffer and carrier oscillator circuit which may be employed in the circuit of the present  FIG. 2 ; 
         [0024]    FIG. 5 of EP 0 592 851 B1 is a detailed schematic example of an amplitude modulation (AM) and power generator  34  and output filter  39  which could be comprised in the circuit of the present  FIG. 2 ; 
         [0025]    FIG. 6 of EP 0 592 851 B1 is a detailed schematic example of an impedance transformer  14  which may be comprised in the circuit of the present  FIG. 2 ; 
         [0026]    FIG. 7 of EP 0 592 851 B1 is a detailed schematic example of an emission sensor  53  which may be comprised in the circuit of the present  FIG. 2 ; 
         [0027]    FIG. 8 of EP 0 592 851 B1 is a detailed schematic example of an output power sensor circuit  54  which may be employed in the circuit of the present  FIG. 2 . 
         [0028]    FIG. 9 of EP 0 592 851 B1 is a detailed schematic example of a display module or information output  17  which may be included in the circuit of the present  FIG. 2 . 
         [0029]    FIG. 10 of EP 0 592 851 B1 is a detailed schematic example of a power supply control circuit including battery charger  57  which may be comprised in the circuit of the present  FIG. 2 . 
         [0030]    FIGS. 11a-d of EP 0 592 851 B1 are exemplary flow charts of the method of operation of the system of  FIGS. 1 and 2 . 
       DETAILED DESCRIPTION 
       [0031]    Referring to  FIG. 1 , presented is a modulated low energy electromagnetic emission application system  11 , in accordance with the present invention. As described in prior U.S. Pat. Nos. 4,649,935 and 4,765,322, such a system has proven to be useful in the practice of Low Energy Emission Therapy (LEET, a trademark of Symtonic S.A. or a successor of this Company), which involves application of emissions of low energy radio frequency (RF) electromagnetic waves to a warm-blooded mammalian subject. The application has proven to be an effective mode of treating a warm-blooded mammalian subject suffering from central nervous system (CNS) disorders such as, for example, generalized anxiety disorders, panic disorders, sleep disorders including insomnia, psychiatric disorders such as depression, obsessive compulsive disorders, disorders resulting from substance abuse, sociopathy, post traumatic stress disorders or other disorders of the central nervous system and combinations thereof. 
         [0032]    The system includes an electrically conductive applicator  12 ,  13  for applying one or more electromagnetic emissions to the warm-blooded mammalian subject. One form of applicator may consist of an electrically conductive probe or mouthpiece  13  which is inserted into the mouth of a subject undergoing treatment. Probe  13  is connected to an electromagnetic energy emitter (see also  FIG. 2 ), through coaxial cable  12  and impedance matching transformer  14 . 
         [0033]    It has previously been considered that an efficient connection of an electrically conductive applicator to a subject could only be achieved by means of a probe which is adapted to be applied to any mucosa of the subject, such as by being located within oral, nasal, optical, urethral, anal, and/or vaginal cavities or surfaces. It has however now been determined that in fact satisfactory application of emissions to a patient can be achieved by simpler physical contact of the electrically conductive applicator with the skin of the patient. Emissions to the patient may, for example be achieved by a conductive, inductive, capacitive or radiated coupling to the patient. An example of a coupling found to be effective involving indirect physical contact with the skin of a patient, is an insulated applicator to be placed over or within an ear of the patient. The emissions thus passed to the patient may be either by capacitive or radiated means or by a combination of both. An important advantage of a device which does not need to be placed in the mouth of a patient is that the patient is able to speak clearly during a time of treatment and can receive treatment during activities of daily living. The treatment is accordingly more user-friendly, can be administered for longer periods of time and can lead to enhanced patient compliance. 
         [0034]    Electronic system  11  also includes a connector or coupler for connection to a programmable device such as a computer or an interface or receiver  16  which is adapted to receive an application storage device  52  such as, for example, magnetic media, semiconductor media, optical media or mechanically encoded media, or programmed emissions programmed with control information employed to control the operation of system  11  so that the desired type of low energy emission therapy is applied to the patient. 
         [0035]    Application storage device  52  can be provided with a microprocessor which, when applied to interface  16 , operates to control the function of system  11  to apply the desired low energy emission therapy. Alternatively, application storage device  52  can be provided with a microprocessor which is used in combination with microprocessor  21  within system  11 . In such case, the microprocessor within device  52  could assist in the interfacing of storage device  52  with system  11 , or could provide security checking functions. 
         [0036]    System  11  may also include a display  17  which can display various indications of the operation of system  11 . In addition, system  11  may include on and off power buttons  18  and  19 , optionally replaced by user interface  21 A (refer to  FIG. 2 ). 
         [0037]    Referring to  FIG. 2 , presented is a block diagram of exemplary electronic circuitry of system  11 , in accordance with the present invention. A data processor, such as for example, microprocessor or integrated circuit  21 , operates as the controller for electronic system  11 , and is connected to control the various components of the system  11 , for example, through address bus  22 , data bus  23  and input/output lines  25 . The block diagram of  FIG. 2  is modified as compared to FIG. 2 of EP 0 592 851 B1 by including what is known as a digital direct synthesizer (DDS)  31  which operates as a accurate and stable modulation frequency generator within the system  11 . An exemplary DDS device is available from Analog Devices of Norwood, Mass. 02062-9106, USA, Part No AD9835. The device is a numerically controlled oscillator and modulation capabilities are provided for phase modulation and frequency modulation. As represented by dotted line block  102 , entitled “PROCESSOR WITH DAC”, the functionality of the DDS may also be combined with microprocessor  21  with digital to analogue converter (DAC). 
         [0038]    Microprocessor  21  preferably includes internal storage for the operation of a coded control program, and temporary data. In addition, microprocessor  21  may include input/output ports and internal timers. Microprocessor  21  may be a microcontroller, for example microcontrollers  8048  or  8051  available from Intel Corporation of Santa Clara, Calif. 95054-1549, USA. 
         [0039]    The timing for microprocessor  21  is provided by system clock oscillator  26 A which may be run at any clock frequency suitable for the particular type of microprocessor used. An exemplary clock frequency is about 8.0 MHz. Oscillator  26 A may be replaced by reference frequency oscillator  26  which secures the stability of the accurate modulation frequency. RF (radio frequency) oscillator  32  may also be employed for this purpose. A combination of oscillators is represented by dotted line block  104 , entitled “OSCILLATOR”. 
         [0040]    An exemplary operating program for microprocessor  21  is presented in flow chart form with reference to FIGS. 11a-d of EP 0 592 851 B1. In general, microprocessor  21  functions to control controllable electromagnetic energy generator circuit  29  to produce a desired form of modulated low energy electromagnetic emission for application to a subject through applicator or probe  13 . 
         [0041]    Dotted line block  29 , entitled CONTROLLABLE GENERATOR, includes DDS modulation frequency generator  31  and carrier signal oscillator  32 . Microprocessor  21  operates to activate or deactivate controllable generator circuit  29  through oscillator disable line  33 , as described in greater detail in EP 0 592 851 B1. Controllable generator circuit  29  also includes an AM modulator and power generator  34  which operates to amplitude modulate a carrier signal produced by carrier oscillator  32  on carrier signal line  36 , with a modulation signal produced by modulation signal generator circuit  31  on modulation signal line  37 . The combination of the functionality of the DDS modulation frequency generator  31 , with processor  21  with DAC, represented by dotted line block  102 , enables output lines  33  and  37  to be combined to produce a single signal. The combination furthermore enables arbitrary or periodic wave forms of any shape to be generated, as similarly described in EP 0 592 851 B1. 
         [0042]    AM modulator and power generator  34  produces an amplitude modulated carrier signal on modulated carrier signal line  38 , which is then applied to emitter output filter circuit  39 . The filter circuit  39  is connected to probe or applicator  13  via power emission sensor  54 , coaxial cable  12  and impedance transformer  14 . 
         [0043]    Microprocessor  21  controls DDS modulation signal generator circuit  31  of controllable generator circuit  29  via interface lines  25 . 
         [0044]    As is illustrated and described in EU 0 592 851 B1, microprocessor  21  may select a desired waveform stored in a modulation waveform storage device  43  and also controls a waveform address generator  41  to produce on waveform address bus  42  a sequence of addresses which are applied to modulation signal storage device  43  in order to retrieve the selected modulation signal. In the embodiment described in EP 0 592 851 B1, the desired modulation signal is retrieved from modulation signal storage device  43  and applied to modulation signal bus  44  in digital form. Modulation signal bus  44  is applied to wave form generator and DAC  46  which converts the digital modulation signal into analogue form. This analogue modulation signal is then applied to a selective filter  47  which, under control of microprocessor  21 , filters the analogue modulation signal by use of a variable filter network including resistor  48  and capacitors  49  and  51  in order to smooth the wave form produced by DAC  46  on modulation signal line  20 . 
         [0045]    A further embodiment possibility is a combination of PROCESSOR WITH DAC dotted line block  102  with OSCILLATOR dotted line block  104  or with a combination of oscillators  26  and  26 A. With such a combination, the hardware solution described in EP 0 592 851 B1 can be realized internally in the processor  102  with multiple outputs  33  and  37  or a single output combining these signals. 
         [0046]    The above embodiment from EP 0 592 851 B1 is in part replaced by the functionality of the DDS modulation frequency modulator  31 . However, if it is determined that emissions of different wave forms is desirable, it would be desirable to include the modulation signal storage device  43  and wave form generator  46  described in EP 0 592 851 B1. Various modulation signal wave forms may then be stored in modulation signal storage device  43 . Wave forms that have been successfully employed include square wave forms or sinusoidal wave forms. Other possible modulation signal wave forms include rectified sinusoidal, triangular, or other wave forms and combinations of all of the above. 
         [0047]    The particular modulation control information employed by microprocessor  21  to control the operation of controllable generator circuit  29 , is stored in application storage device  52 . The application storage device is conveniently a computer comprising or being for receiving the information. Alternatively, application storage devices illustrated and described in EP 0 592 851 B1, with reference to FIGS. 12, 13, 14 and 15, may be selected. 
         [0048]    Interface  16  is configured as appropriate for the particular application storage device  52  in use. Interface  16  translates the control information stored in application storage device  52  into a usable form for storage within the memory of microprocessor  21  to enable microprocessor  21  to control controllable generator circuit  29  to produce the desired modulated low energy emission. 
         [0049]    Interface  16  may directly read the information stored on application storage device  52 , or it may read the information through use of various known communication links. For example, radio frequency, microwave, laser, telephone, internet or optical based communications links may be employed to transfer information between interface or receiver  16  and application storage device or computer  52 . 
         [0050]    The system  11  may comprise a user identification device, included in block  21   a  in  FIG. 2 . Conveniently, such a device communicates with the one or more data processors or integrated circuits  21  via interface  16 , as shown. The user identification device may be of any type, a finger print reader being an example. Such a reader is for example available from Lenovo, 70563 Stuttgart, Germany, Part No. 73P4774. 
         [0051]    The control information stored in application storage device or computer  52  specifies various controllable parameters of the modulated low energy RF electromagnetic emission to be applied to a subject through applicator or probe  13 . Such controllable parameters include, for example, but are not necessarily limited to, the frequency and amplitude of the carrier, the amplitudes and frequencies and wave forms of the modulation of the carrier, the duration of the emission, the power level of the emission, the duty cycle of the emission (i.e., the ratio of on time to off time of pulsed emissions applied during a treatment), the sequence of application of different modulation frequencies for a particular application, and the total number of treatments and duration of each treatment prescribed for a particular subject, and combinations thereof. 
         [0052]    For example, the carrier signal and modulation signal may be selected to drive the applicator or probe  13  with an amplitude modulated signal in which the carrier signal includes spectral frequency components below about 1 GHz, and preferably between about 1 MHz and about 900 MHz, and in which the modulation signal comprises spectral frequency components between about 0.01 Hz and 150 KHz. The one or more modulation frequencies may be simultaneously emitted or sequenced to form the modulation signal. 
         [0053]    As an additional feature, an electromagnetic emission sensor  53  may be provided to detect the presence of electromagnetic emissions at the frequency of the carrier oscillator  32 . Emission sensor  53  provides microprocessor  21  with an indication of whether or not electromagnetic emissions at the desired frequency are present. Microprocessor  21  then takes appropriate action, for example, by displaying an error message on display  17 , disabling controllable generator circuit  29 , or the like. 
         [0054]    A power sensor  54  is preferably included which detects the amount of power applied to the subject through applicator or probe  13  compared to the amount of power returned or reflected from the subject. This ratio is indicative of the proper use of the system during a therapeutic session. Power sensor  54  applies to microprocessor  21 , through power sensor line  56 , an indication of the amount of power applied to patient through applicator or probe  13  relative to the amount of power reflected from the patient. 
         [0055]    The indication provided on power sense line  56  may be digitalized and employed by microprocessor  21 , for example, to detect and control a level of applied power, and to record on application storage device  52  information related to the actual treatments applied to and received by the patient. Such information may then be used by a physician or other clinician to assess patient treatment compliance and effect. Such treatment information may include, for example: the number of treatments applied for a given time period; the actual time and date of each treatment; the number of attempted treatments; the treatment compliance (i.e., whether the applicator or probe was in place or not during the treatment session); and the cumulative dose of a particular modulation frequency. 
         [0056]    The level of power applied is preferably controlled to cause the specific absorption rate (SAR) of energy absorbed by the patient to be from about 1 microWatt per kilogram of tissue to about 50 Watts per kilogram of tissue. Preferably, the power level is controlled to cause an SAR of from about 100 microWatts per kilogram of tissue to about 10 Watts per kilogram of tissue. Most preferably, the power level is controlled to cause an SAR of from about 1 milliWatt per kilogram of tissue to about 100 milliWatts per kilogram of tissue. These SARs may be in any tissue of the patient, but are preferably in the tissue of the central nervous system or the diseased tissue. 
         [0057]    System  11  may also include powering circuitry including battery and charger circuit  57  and battery voltage change detector  58 . 
         [0058]    The RF carrier oscillator  32  produces a RF carrier frequency of about 27 MHz. Other embodiments of the invention contemplate RF carrier frequencies of about 48 MHz, about 433 MHz or about 900 MHz. In general, the RF carrier frequency produced by carrier oscillator  32  has spectral frequency components less than about 1 GHz and preferably between about 1 MHz and about 916 MHz. Although the described embodiment contemplates that once set, the carrier oscillator frequency remains substantially constant, the carrier frequency produced by carrier oscillator  32  may be variable and controllable by microprocessor  21  by use of stored or transmitted control information. 
         [0059]    Carrier oscillator  32  produces on carrier signal line  36  a carrier signal which is then modulated by the modulation signal carried on signal line  37 . 
         [0060]    Oscillator disable line  33  enables microprocessor  21  to disable the signal from oscillator  32  by applying an appropriate disable signal to oscillator disable line  33 . 
         [0061]    The output of the AM modulator and power generator  34  appears on signal line  38 . This modulated signal is applied through emitter output filter  39  which substantially reduces or eliminates the carrier harmonics resulting from side effects of the modulator and power generator circuit  34 . 
         [0062]    The output of the AM modulator and power generator  34  and emitter output filter  39  may be designed to possess a 50 Ohm output impedance to match a 50 Ohm impedance of coaxial cable  12 . 
         [0063]    It has been determined through impedance measurements that when a probe  13  is applied within the mouth of a subject, the probe/subject combination exhibits a complex impedance of the order of about 150+j200 Ohms. Impedance transformer  14  serves to match this complex impedance with the 50 Ohm impedance of coaxial cable  12  and therefore the output impedance of the AM modulator  34  and output filter  39 . This promotes power transmission, and minimizes reflections. 
         [0064]    The arrangement described above has been optimized for a contact probe with coupling to the mucosa of the mouth. In a further example, a conductive, isolated probe has been used at a frequency around 433 MHz coupling to the outer ear channel. Due to the different probe design in such a frequency band and with this coupling method, the values of matching elements (79 and 81 described in EP 0592 851 B1) would be different or could even be omitted. Applicator or probe  13  may then be regarded as a capacitive coupler or as an antenna matched to the capacitive load. 
         [0065]    As described in EP 0 592 851 B1, with reference to the flow charts of FIGS. 11a-d, microprocessor  21  may operate to analyse the signal appearing on power sense line  56  to determine and control the amount of power applied to the patient, and to assess patient treatment compliance, and possibly to record indicia of the patient treatment compliance on application storage device  52  for later analysis and assessment by a physician or other clinician. 
         [0066]    Exemplary of treatments performed on patients have included brain, bladder, colorectal, kidney, mesothelium, neuroendocrine, liver, lung, breast, ovary, pancreas, prostate and thyroid tumour types. The treatments involved applying an about 27.12 MHz RF signal, amplitude modulated at specifically defined frequencies ranging from about 0.2 to about 23,000 Hz at very high precision and stability. Further Examples of treatment modes (at specific accurately controlled AM frequencies) for specified types of tumours are described in detail below. 
         [0067]    The following are synopses of abstracts for future publications related to uses of electronic devices of the present invention: 
       A 
     Example A 
     A Phase I Study of Therapeutic Amplitude-Modulated Electromagnetic Fields (THERABIONIC) in Advanced Tumors 
       [0068]    Boris Pasche  1 , Alexandre Barbault  1 , Brad Bottger  2 , Fin Bomholt  3 , Niels Kuster  4 .  1  Cabinet Médical de l&#39;Avenue de la Gare 6, CH-1003-Lausanne, Switzerland. 2  Danbury Hospital, Danbury, Conn.-06810. 3  SPEAG, Zurich, CH-8004-Zurich, Switzerland 4  IT&#39;IS Foundation, Swiss Federal Institute of Technology, Zurich, Switzerland. 
         [0069]    Background: In vitro studies suggest that low levels of amplitude-modulated electromagnetic fields may modify cell growth. Specific frequencies have been identified specific frequencies that may block cancer cell growth. A portable and programmable device capable of delivering low levels of amplitude-modulated electromagnetic fields has been developed. The device emits a 27.12 MHz radiofrequency signal, amplitude-modulated at cancer-specific frequencies ranging from 0.2 to 23,000 Hz with high precision. The device is connected to a spoon-like coupler, which is placed in the patient&#39;s mouth during treatment. 
         [0070]    Methods: A phase I study was conducted consisting of three daily 40 min treatments. From March 2004 to September 2006, 24 patients with advanced solid tumors were enrolled. The median age was 57.0±12.2 years. 16 patients were female. As of January 2007, 5 patients are still on therapy, 13 patients died of tumor progression, 2 patients are lost to follow-up and one patient withdrew consent. The most common tumor types were breast (7), ovary (5) and pancreas (3). 22 patients had received prior systemic therapy and 16 had documented tumor progression prior to study entry. 
         [0071]    Results: The median duration of therapy was 15.7±19.9 weeks (range: 0.4-72.0 weeks). There were no NCI grade 2, 3 or 4 toxicities. Three patients experienced grade 1 fatigue during and immediately after treatment. 12 patients reported severe pain prior to study entry. Two of them reported significant pain relief with the treatment. Objective response could be assessed in 13 patients, 6 of whom also had elevated tumor markers. 6 additional patients could only be assessed by tumor markers. Among patients with progressive disease at study entry, one had a partial response for &gt;14.4 weeks associated with &gt;50% decrease in CEA, CA 125 and CA 15-3 (previously untreated metastatic breast cancer); one patient had stable disease for 34.6 weeks (add info); one patient had a 50% decrease in CA 19-9 for 12.4 weeks (recurrent pancreatic cancer). Among patients with stable disease at enrollment, four patients maintained stable disease for 17.0, &gt;19.4, 30.4 and &gt;63.4 weeks. 
         [0072]    Conclusions: The treatment is a safe and promising novel treatment modality for advanced cancer. A phase II study and molecular studies are ongoing to confirm those results. 
       Example B 
     A Phase II Study of Therapeutic Amplitude-Modulated Electromagnetic Fields (THERABIONIC) in the Treatment of Advanced Hepatocellular Carcinoma (HCC) 
       [0073]    Frederico P Costa  1 , Andre Cosme de Oliveira  1 , Roberto Meirelles Jr  1 , Rodrigo Surjan  1 , Tatiana Zanesco  1 , Maria Cristina Chammas  1 , Alexandre Barbault  2 , Boris Pasche  2 .  1  Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.  2 Cabinet Médical Avenue de la Gare 6, CH-1003-Lausanne, Switzerland 
         [0074]    Background: Phase I data suggest that low levels of electromagnetic fields amplitude-modulated at specific frequencies administered intrabucally with the device of Example A are a safe and potentially effective treatment for advanced cancer. The device emits a 27.12 MHz RF signal, amplitude-modulated with cancer-specific frequencies ranging from 0.2 to 23,000 Hz with high precision. The device is connected to a spoon-like coupler placed in the patient&#39;s mouth during treatment. Patients with advanced hepatocellular carcinoma HCC and limited therapeutic options were offered treatment with a combination of HCC-specific frequencies. 
         [0075]    Methods: From October 2005 to October 2006, 38 patients with advanced HCC were recruited in a phase II study. The patients received three daily 40 min treatments until disease progression or death. The median age was 64.0±14.2 years. 32 patients were male and 29 patients had documented progression of disease (POD) prior to study entry. 
         [0076]    Results: As of January 2007, 12 patients are still on therapy, 20 patients died of tumor progression, 2 patients are lost to follow-up and 3 patients withdrew consent. 27 patients are eligible for response. The overall objective response rate as defined by partial response (PR) or stable disease (SD) in patients with documented POD at study entry was 31.6%: 3 PR and 9 SD. The median survival was 20.7 weeks with a median duration of therapy of 17.5 weeks. 13 patients have received therapy for more than six months. The median duration of response is 12.9 weeks. 12 patients reported pain at study entry: 8 of them (66%) experienced decreased pain during treatment. There were no NCI grade 2/3/4 toxicities. One patient developed grade 1 mucositis and grade 1 fatigue. 
         [0000]    
       
         
               
               
               
               
               
             
               
               
               
               
             
               
               
               
               
               
             
           
               
                   
               
             
             
               
                 Patient characteristics (n = 38) 
                   
                   
                   
                   
               
             
          
           
               
                 Cirrhosis 
                 36 
                   
                   
               
               
                 Portal vein thrombosis 
                 9 
               
               
                 Elevated AFP 
                 25 
               
               
                 Extra-hepatic metastases 
                 12 
               
               
                 Previous intrahepatic/systemic therapy 
                 30 
               
               
                 Previous hepatic resection/RFA or 
                 8 
               
               
                 ethanol 
               
             
          
           
               
                 CLIP 
                 0/1: 
                 12 
                 &gt;2: 
                 22 
               
               
                 Okuda 
                 I: 
                 14 
                 II/III: 
                 20 
               
               
                 Child-Pugh 
                 A: 
                 15 
                 B: 
                 19 
               
               
                 MELD 
                 Median: 
                 10 
               
               
                   
               
             
          
         
       
     
         [0077]    Conclusion: In patients with advanced HCC the treatment is a safe and effective novel therapeutic option, which has antitumor effect and provides pain relief in the majority of patients. 
         [0078]    Thus, it is seen that the electronic device of the present invention, comprising means for the accurate control over the frequencies and stability of amplitude modulations of a high frequency carrier signal, provides a safe and promising novel treatment modality for the treatment of patients suffering from various types of advanced forms of cancer. 
         [0079]    Exemplary of above accurately controlled amplitude modulated frequencies controlling the frequency of amplitude modulations of a high frequency carrier signal are set forth below along with the type of cancer or tumour harboured by a subject to be treated. 
       Example 1 
     AM Frequencies Employed for Treatment of Breast Cancer (188 Frequencies so Far Included) 
       [0080]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                   78.76 Hz 
               
               
                  181.821 Hz 
               
               
                  414.817 Hz 
               
               
                  440.933 Hz 
               
               
                  628.431 Hz 
               
               
                  721.313 Hz 
               
               
                  813.205 Hz 
               
               
                  818.342 Hz 
               
               
                  891.901 Hz 
               
               
                  929.095 Hz 
               
               
                   929.1 Hz 
               
               
                    1021 Hz 
               
               
                 1372.207 Hz 
               
               
                 1372.934 Hz 
               
               
                 1588.721 Hz 
               
               
                 1670.699 Hz 
               
               
                 1821.729 Hz 
               
               
                 1836.219 Hz 
               
               
                 2193.937 Hz 
               
               
                 2221.323 Hz 
               
               
                 2278.312 Hz 
               
               
                 2357.832 Hz 
               
               
                 2381.443 Hz 
               
               
                 2417.323 Hz 
               
               
                 2431.334 Hz 
               
               
                 2450.332 Hz 
               
               
                 2551.313 Hz 
               
               
                 2556.221 Hz 
               
               
                 2598.853 Hz 
               
               
                 2621.322 Hz 
               
               
                 2740.191 Hz 
               
               
                 2851.347 Hz 
               
               
                 2885.322 Hz 
               
               
                 2919.273 Hz 
               
               
                 3074.333 Hz 
               
               
                 3115.188 Hz 
               
               
                 3249.529 Hz 
               
               
                 3405.182 Hz 
               
               
                 3432.274 Hz 
               
               
                 3434.693 Hz 
               
               
                 3594.231 Hz 
               
               
                 3647.619 Hz 
               
               
                 3742.957 Hz 
               
               
                 3753.382 Hz 
               
               
                 3830.732 Hz 
               
               
                 3855.823 Hz 
               
               
                 3916.321 Hz 
               
               
                 3935.218 Hz 
               
               
                 3975.383 Hz 
               
               
                 3993.437 Hz 
               
               
                 4153.192 Hz 
               
               
                 4194.968 Hz 
               
               
                 4241.321 Hz 
               
               
                 4243.393 Hz 
               
               
                 4253.432 Hz 
               
               
                 4314.444 Hz 
               
               
                 4318.222 Hz 
               
               
                 4375.962 Hz 
               
               
                 4393.419 Hz 
               
               
                 4417.243 Hz 
               
               
                 4481.463 Hz 
               
               
                 4482.223 Hz 
               
               
                 4495.138 Hz 
               
               
                 4549.808 Hz 
               
               
                 4558.306 Hz 
               
               
                 4779.451 Hz 
               
               
                 4838.674 Hz 
               
               
                 4871.513 Hz 
               
               
                 4895.296 Hz 
               
               
                 4962.213 Hz 
               
               
                 4969.224 Hz 
               
               
                 4979.321 Hz 
               
               
                 5027.231 Hz 
               
               
                 5059.792 Hz 
               
               
                 5118.094 Hz 
               
               
                 5176.287 Hz 
               
               
                 5365.222 Hz 
               
               
                 5376.392 Hz 
               
               
                 5426.323 Hz 
               
               
                 5431.542 Hz 
               
               
                 5521.621 Hz 
               
               
                 5739.422 Hz 
               
               
                 5745.218 Hz 
               
               
                 5821.975 Hz 
               
               
                 6037.432 Hz 
               
               
                 6044.333 Hz 
               
               
                 6086.256 Hz 
               
               
                 6208.932 Hz 
               
               
                 6212.808 Hz 
               
               
                 6231.031 Hz 
               
               
                 6280.321 Hz 
               
               
                 6329.391 Hz 
               
               
                 6476.896 Hz 
               
               
                 6497.319 Hz 
               
               
                 6504.983 Hz 
               
               
                 6651.276 Hz 
               
               
                 6757.901 Hz 
               
               
                 6758.321 Hz 
               
               
                 6855.286 Hz 
               
               
                 6858.121 Hz 
               
               
                 6898.489 Hz 
               
               
                 7092.219 Hz 
               
               
                 7120.218 Hz 
               
               
                 7127.311 Hz 
               
               
                 7156.489 Hz 
               
               
                 7208.821 Hz 
               
               
                 7282.169 Hz 
               
               
                 7376.329 Hz 
               
               
                 7488.742 Hz 
               
               
                 7541.319 Hz 
               
               
                 7577.421 Hz 
               
               
                 7621.085 Hz 
               
               
                 7627.207 Hz 
               
               
                 7650.939 Hz 
               
               
                 7691.212 Hz 
               
               
                 7842.184 Hz 
               
               
                 7849.231 Hz 
               
               
                 7915.423 Hz 
               
               
                 7932.482 Hz 
               
               
                 7949.196 Hz 
               
               
                 7967.311 Hz 
               
               
                 8021.229 Hz 
               
               
                 8070.181 Hz 
               
               
                 8114.032 Hz 
               
               
                 8149.922 Hz 
               
               
                  8194.19 Hz 
               
               
                 8245.801 Hz 
               
               
                 8328.322 Hz 
               
               
                 8330.534 Hz 
               
               
                 8355.987 Hz 
               
               
                 8408.121 Hz 
               
               
                 8431.184 Hz 
               
               
                 8452.119 Hz 
               
               
                 8548.324 Hz 
               
               
                 8749.383 Hz 
               
               
                 8782.421 Hz 
               
               
                 8784.424 Hz 
               
               
                  8923.1 Hz 
               
               
                 8923.361 Hz 
               
               
                 8935.752 Hz 
               
               
                  8936.1 Hz 
               
               
                 9012.282 Hz 
               
               
                 9012.896 Hz 
               
               
                 9060.323 Hz 
               
               
                 9072.409 Hz 
               
               
                 9131.419 Hz 
               
               
                 9199.232 Hz 
               
               
                 9245.927 Hz 
               
               
                 9270.322 Hz 
               
               
                 9279.193 Hz 
               
               
                 9393.946 Hz 
               
               
                 10227.242 Hz  
               
               
                 10340.509 Hz  
               
               
                 10363.313 Hz  
               
               
                 10449.323 Hz  
               
               
                 10456.383 Hz  
               
               
                 10468.231 Hz  
               
               
                 10470.456 Hz  
               
               
                 10472.291 Hz  
               
               
                 10689.339 Hz  
               
               
                 10832.222 Hz  
               
               
                 11525.121 Hz  
               
               
                 11541.915 Hz  
               
               
                 11812.328 Hz  
               
               
                 11812.419 Hz  
               
               
                 11840.323 Hz  
               
               
                 11925.089 Hz  
               
               
                 12123.281 Hz  
               
               
                 12267.281 Hz  
               
               
                 12294.283 Hz  
               
               
                 12611.288 Hz  
               
               
                 12629.222 Hz  
               
               
                 12633.372 Hz  
               
               
                 12648.221 Hz  
               
               
                 13315.335 Hz  
               
               
                 13331.358 Hz  
               
               
                 13735.241 Hz  
               
               
                 13826.325 Hz  
               
               
                 13853.232 Hz  
               
               
                 13990.123 Hz  
               
               
                 14122.942 Hz  
               
               
                 14162.332 Hz  
               
               
                 14519.232 Hz  
               
               
                 14543.128 Hz  
               
               
                 15651.323 Hz  
               
               
                 17352.085 Hz  
               
               
                 18785.463 Hz  
               
               
                 30182.932 Hz  
               
               
                   
               
             
          
         
       
     
       Example 2 
     AM Frequencies Employed for Treatment of Liver Cancer (162 Frequencies so Far Included) 
       [0081]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  423.321 Hz 
               
               
                  427.062 Hz 
               
               
                  470.181 Hz 
               
               
                  560.32 Hz 
               
               
                  642.932 Hz 
               
               
                  668.209 Hz 
               
               
                  677.972 Hz 
               
               
                  811.924 Hz 
               
               
                  842.311 Hz 
               
               
                  843.22 Hz 
               
               
                 1250.504 Hz 
               
               
                 1755.402 Hz 
               
               
                 1873.477 Hz 
               
               
                 1924.702 Hz 
               
               
                 1975.196 Hz 
               
               
                 2017.962 Hz 
               
               
                 2083.419 Hz 
               
               
                 2190.731 Hz 
               
               
                 2221.323 Hz 
               
               
                 2324.393 Hz 
               
               
                 2353.478 Hz 
               
               
                 2362.309 Hz 
               
               
                 2419.309 Hz 
               
               
                 2425.222 Hz 
               
               
                 2430.219 Hz 
               
               
                 2431.094 Hz 
               
               
                 2471.328 Hz 
               
               
                 2478.331 Hz 
               
               
                 2743.995 Hz 
               
               
                 2744.211 Hz 
               
               
                 2831.951 Hz 
               
               
                 2843.283 Hz 
               
               
                 2859.891 Hz 
               
               
                 2873.542 Hz 
               
               
                 2886.232 Hz 
               
               
                 3042.012 Hz 
               
               
                 3078.983 Hz 
               
               
                 3086.443 Hz 
               
               
                 3127.232 Hz 
               
               
                 3160.942 Hz 
               
               
                 3206.315 Hz 
               
               
                 3267.433 Hz 
               
               
                 3269.321 Hz 
               
               
                 3457.291 Hz 
               
               
                 3505.229 Hz 
               
               
                 3516.296 Hz 
               
               
                 3531.296 Hz 
               
               
                 3546.323 Hz 
               
               
                 3572.106 Hz 
               
               
                 3576.189 Hz 
               
               
                 3669.513 Hz 
               
               
                 3923.221 Hz 
               
               
                 4013.932 Hz 
               
               
                 4071.121 Hz 
               
               
                 4079.951 Hz 
               
               
                 4222.821 Hz 
               
               
                 4238.402 Hz 
               
               
                 4256.321 Hz 
               
               
                 4289.296 Hz 
               
               
                 4312.947 Hz 
               
               
                 4435.219 Hz 
               
               
                 4471.188 Hz 
               
               
                 4483.889 Hz 
               
               
                 4486.384 Hz 
               
               
                 4629.941 Hz 
               
               
                 4732.211 Hz 
               
               
                 4876.218 Hz 
               
               
                 5086.281 Hz 
               
               
                 5124.084 Hz 
               
               
                 5133.121 Hz 
               
               
                 5247.142 Hz 
               
               
                 5270.834 Hz 
               
               
                 5340.497 Hz 
               
               
                 5520.218 Hz 
               
               
                 5882.292 Hz 
               
               
                 5926.512 Hz 
               
               
                 6037.311 Hz 
               
               
                 6180.334 Hz 
               
               
                 6329.195 Hz 
               
               
                 6350.333 Hz 
               
               
                 6361.321 Hz 
               
               
                 6364.928 Hz 
               
               
                 6383.321 Hz 
               
               
                 6461.175 Hz 
               
               
                 6733.331 Hz 
               
               
                 6758.232 Hz 
               
               
                 6779.482 Hz 
               
               
                 6856.222 Hz 
               
               
                 6877.183 Hz 
               
               
                 6980.525 Hz 
               
               
                 7019.235 Hz 
               
               
                 7043.209 Hz 
               
               
                 7130.323 Hz 
               
               
                 7144.142 Hz 
               
               
                 7210.223 Hz 
               
               
                  7291.21 Hz 
               
               
                  7510.92 Hz 
               
               
                 7529.233 Hz 
               
               
                 7549.212 Hz 
               
               
                 7650.028 Hz 
               
               
                 7680.518 Hz 
               
               
                 7692.522 Hz 
               
               
                 7829.231 Hz 
               
               
                 7862.209 Hz 
               
               
                 7947.392 Hz 
               
               
                 7979.308 Hz 
               
               
                 8028.339 Hz 
               
               
                 8055.942 Hz 
               
               
                 8072.134 Hz 
               
               
                 8141.174 Hz 
               
               
                 8336.383 Hz 
               
               
                 8432.181 Hz 
               
               
                 8452.119 Hz 
               
               
                 8460.944 Hz 
               
               
                 8475.221 Hz 
               
               
                 8492.193 Hz 
               
               
                 8542.311 Hz 
               
               
                 8818.104 Hz 
               
               
                 8852.329 Hz 
               
               
                 8853.444 Hz 
               
               
                 8858.179 Hz 
               
               
                 8939.212 Hz 
               
               
                 9332.397 Hz 
               
               
                 9381.221 Hz 
               
               
                 9740.219 Hz 
               
               
                 9768.331 Hz 
               
               
                 9797.294 Hz 
               
               
                 10317.499 Hz  
               
               
                 10443.311 Hz  
               
               
                 10456.383 Hz  
               
               
                 10579.425 Hz  
               
               
                 10863.209 Hz  
               
               
                 10866.382 Hz  
               
               
                 11067.418 Hz  
               
               
                 11149.935 Hz  
               
               
                 11163.895 Hz  
               
               
                 11802.821 Hz  
               
               
                 11953.424 Hz  
               
               
                 12223.329 Hz  
               
               
                 12265.295 Hz  
               
               
                 12267.233 Hz  
               
               
                 12623.191 Hz  
               
               
                 12685.231 Hz  
               
               
                 12721.423 Hz  
               
               
                 12785.342 Hz  
               
               
                 14085.222 Hz  
               
               
                 14333.209 Hz  
               
               
                 14537.331 Hz  
               
               
                 14542.432 Hz  
               
               
                 14655.03 Hz 
               
               
                 14828.234 Hz  
               
               
                 15149.213 Hz  
               
               
                 15237.489 Hz  
               
               
                 16110.932 Hz  
               
               
                 16144.343 Hz  
               
               
                 18265.238 Hz  
               
               
                 18283.323 Hz  
               
               
                 18863.292 Hz  
               
               
                 18930.995 Hz  
               
               
                 19970.311 Hz  
               
               
                 20330.294 Hz  
               
               
                 20365.284 Hz  
               
               
                   
               
             
          
         
       
     
       Example 3 
     AM Frequencies Employed for Treatment of Ovarian Cancer (273 Frequencies so Far Included) 
       [0082]      
         [0000]    
       
         
               
               
             
           
               
                   
               
             
             
               
                 78.76 
                 Hz 
               
               
                 181.821 
                 Hz 
               
               
                 410.245 
                 Hz 
               
               
                 414.817 
                 Hz 
               
               
                 436.332 
                 Hz 
               
               
                 447.942 
                 Hz 
               
               
                 481.191 
                 Hz 
               
               
                 489.292 
                 Hz 
               
               
                 559.292 
                 Hz 
               
               
                 608.321 
                 Hz 
               
               
                 655.435 
                 Hz 
               
               
                 657.397 
                 Hz 
               
               
                 657.483 
                 Hz 
               
               
                 664.211 
                 Hz 
               
               
                 708.8 
                 Hz 
               
               
                 708.822 
                 Hz 
               
               
                 734.921 
                 Hz 
               
               
                 749.221 
                 Hz 
               
               
                 764.232 
                 Hz 
               
               
                 778.295 
                 Hz 
               
               
                 779.403 
                 Hz 
               
               
                 806.021 
                 Hz 
               
               
                 806.389 
                 Hz 
               
               
                 809.313 
                 Hz 
               
               
                 824.327 
                 Hz 
               
               
                 825.145 
                 Hz 
               
               
                 835.129 
                 Hz 
               
               
                 839.521 
                 Hz 
               
               
                 841.208 
                 Hz 
               
               
                 843.312 
                 Hz 
               
               
                 956.984 
                 Hz 
               
               
                 958.929 
                 Hz 
               
               
                 985.313 
                 Hz 
               
               
                 1024.208 
                 Hz 
               
               
                 1102.635 
                 Hz 
               
               
                 1121.329 
                 Hz 
               
               
                 1159.738 
                 Hz 
               
               
                 1372.207 
                 Hz 
               
               
                 1396.498 
                 Hz 
               
               
                 1502.181 
                 Hz 
               
               
                 1518.208 
                 Hz 
               
               
                 1552.123 
                 Hz 
               
               
                 1579.212 
                 Hz 
               
               
                 1624.802 
                 Hz 
               
               
                 1670.699 
                 Hz 
               
               
                 1696.403 
                 Hz 
               
               
                 1762.938 
                 Hz 
               
               
                 1771.402 
                 Hz 
               
               
                 1775.313 
                 Hz 
               
               
                 1821.729 
                 Hz 
               
               
                 2016.323 
                 Hz 
               
               
                 2034.231 
                 Hz 
               
               
                 2050.282 
                 Hz 
               
               
                 2053.396 
                 Hz 
               
               
                 2082.234 
                 Hz 
               
               
                 2089.092 
                 Hz 
               
               
                 2221.323 
                 Hz 
               
               
                 2228.832 
                 Hz 
               
               
                 2253.704 
                 Hz 
               
               
                 2254.329 
                 Hz 
               
               
                 2278.312 
                 Hz 
               
               
                 2332.949 
                 Hz 
               
               
                 2348.233 
                 Hz 
               
               
                 2381.443 
                 Hz 
               
               
                 2413.193 
                 Hz 
               
               
                 2425.222 
                 Hz 
               
               
                 2433.321 
                 Hz 
               
               
                 2439.253 
                 Hz 
               
               
                 2465.23 
                 Hz 
               
               
                 2477.919 
                 Hz 
               
               
                 2669.177 
                 Hz 
               
               
                 2715.232 
                 Hz 
               
               
                 2733.843 
                 Hz 
               
               
                 2802.339 
                 Hz 
               
               
                 2812.321 
                 Hz 
               
               
                 2831.386 
                 Hz 
               
               
                 2835.332 
                 Hz 
               
               
                 2851.347 
                 Hz 
               
               
                 2877.192 
                 Hz 
               
               
                 2885.322 
                 Hz 
               
               
                 2887.385 
                 Hz 
               
               
                 2894.972 
                 Hz 
               
               
                 2973.771 
                 Hz 
               
               
                 3080.592 
                 Hz 
               
               
                 3157.483 
                 Hz 
               
               
                 3161.465 
                 Hz 
               
               
                 3223.232 
                 Hz 
               
               
                 3238.148 
                 Hz 
               
               
                 3249.529 
                 Hz 
               
               
                 3262.145 
                 Hz 
               
               
                 3314.321 
                 Hz 
               
               
                 3361.671 
                 Hz 
               
               
                 3366.311 
                 Hz 
               
               
                 3523.215 
                 Hz 
               
               
                 3527.233 
                 Hz 
               
               
                 3542.213 
                 Hz 
               
               
                 3590.376 
                 Hz 
               
               
                 3629.232 
                 Hz 
               
               
                 3632.793 
                 Hz 
               
               
                 3636.289 
                 Hz 
               
               
                 3637.085 
                 Hz 
               
               
                 3669.513 
                 Hz 
               
               
                 3770.189 
                 Hz 
               
               
                 3858.916 
                 Hz 
               
               
                 3919.232 
                 Hz 
               
               
                 3957.185 
                 Hz 
               
               
                 3975.228 
                 Hz 
               
               
                 4061.131 
                 Hz 
               
               
                 4072.322 
                 Hz 
               
               
                 4169.451 
                 Hz 
               
               
                 4174.259 
                 Hz 
               
               
                 4241.321 
                 Hz 
               
               
                 4243.393 
                 Hz 
               
               
                 4261.228 
                 Hz 
               
               
                 4279.113 
                 Hz 
               
               
                 4309.335 
                 Hz 
               
               
                 4314.188 
                 Hz 
               
               
                 4318.222 
                 Hz 
               
               
                 4328.928 
                 Hz 
               
               
                 4380.321 
                 Hz 
               
               
                 4394.134 
                 Hz 
               
               
                 4412.252 
                 Hz 
               
               
                 4424.236 
                 Hz 
               
               
                 4439.341 
                 Hz 
               
               
                 4442.161 
                 Hz 
               
               
                 4447.221 
                 Hz 
               
               
                 4458.339 
                 Hz 
               
               
                 4556.322 
                 Hz 
               
               
                 4566.009 
                 Hz 
               
               
                 4682.643 
                 Hz 
               
               
                 4718.331 
                 Hz 
               
               
                 4749.302 
                 Hz 
               
               
                 4765.331 
                 Hz 
               
               
                 4917.202 
                 Hz 
               
               
                 5011.325 
                 Hz 
               
               
                 5149.331 
                 Hz 
               
               
                 5228.172 
                 Hz 
               
               
                 5237.132 
                 Hz 
               
               
                 5313.353 
                 Hz 
               
               
                 5745.218 
                 Hz 
               
               
                 5757.897 
                 Hz 
               
               
                 5762.386 
                 Hz 
               
               
                 5812.322 
                 Hz 
               
               
                 5869.321 
                 Hz 
               
               
                 5882.292 
                 Hz 
               
               
                 5921.249 
                 Hz 
               
               
                 5991.932 
                 Hz 
               
               
                 6069.458 
                 Hz 
               
               
                 6071.319 
                 Hz 
               
               
                 6083.214 
                 Hz 
               
               
                 6161.782 
                 Hz 
               
               
                 6169.341 
                 Hz 
               
               
                 6275.232 
                 Hz 
               
               
                 6294.929 
                 Hz 
               
               
                 6350.333 
                 Hz 
               
               
                 6406.891 
                 Hz 
               
               
                 6407.207 
                 Hz 
               
               
                 6450.787 
                 Hz 
               
               
                 6477.098 
                 Hz 
               
               
                 6477.929 
                 Hz 
               
               
                 6478.338 
                 Hz 
               
               
                 6543.421 
                 Hz 
               
               
                 6552.24 
                 Hz 
               
               
                 6663.955 
                 Hz 
               
               
                 6753.338 
                 Hz 
               
               
                 6851.323 
                 Hz 
               
               
                 6855.286 
                 Hz 
               
               
                 6875.232 
                 Hz 
               
               
                 6882.949 
                 Hz 
               
               
                 7206.403 
                 Hz 
               
               
                 7232.214 
                 Hz 
               
               
                 7257.489 
                 Hz 
               
               
                 7276.209 
                 Hz 
               
               
                 7281.219 
                 Hz 
               
               
                 7285.693 
                 Hz 
               
               
                 7429.212 
                 Hz 
               
               
                 7460.932 
                 Hz 
               
               
                 7480.228 
                 Hz 
               
               
                 7495.763 
                 Hz 
               
               
                 7539.432 
                 Hz 
               
               
                 7564.185 
                 Hz 
               
               
                 7650.028 
                 Hz 
               
               
                 7689.728 
                 Hz 
               
               
                 7780.294 
                 Hz 
               
               
                 8021.921 
                 Hz 
               
               
                 8038.961 
                 Hz 
               
               
                 8040.322 
                 Hz 
               
               
                 8044.233 
                 Hz 
               
               
                 8095.313 
                 Hz 
               
               
                 8143.491 
                 Hz 
               
               
                 8164.332 
                 Hz 
               
               
                 8261.121 
                 Hz 
               
               
                 8302.285 
                 Hz 
               
               
                 8309.752 
                 Hz 
               
               
                 8372.532 
                 Hz 
               
               
                 8408.121 
                 Hz 
               
               
                 8424.229 
                 Hz 
               
               
                 8428.313 
                 Hz 
               
               
                 8435.451 
                 Hz 
               
               
                 8486.421 
                 Hz 
               
               
                 8492.797 
                 Hz 
               
               
                 8548.324 
                 Hz 
               
               
                 8554.361 
                 Hz 
               
               
                 8562.965 
                 Hz 
               
               
                 8579.323 
                 Hz 
               
               
                 8579.333 
                 Hz 
               
               
                 8642.181 
                 Hz 
               
               
                 8655.818 
                 Hz 
               
               
                 8758.341 
                 Hz 
               
               
                 8779.323 
                 Hz 
               
               
                 8792.231 
                 Hz 
               
               
                 8819.127 
                 Hz 
               
               
                 8831.132 
                 Hz 
               
               
                 9028.031 
                 Hz 
               
               
                 9173.264 
                 Hz 
               
               
                 9184.338 
                 Hz 
               
               
                 9186.919 
                 Hz 
               
               
                 9393.946 
                 Hz 
               
               
                 9482.409 
                 Hz 
               
               
                 9737.211 
                 Hz 
               
               
                 9746.232 
                 Hz 
               
               
                 9922.231 
                 Hz 
               
               
                 10032.684 
                 Hz 
               
               
                 10446.028 
                 Hz 
               
               
                 10478.221 
                 Hz 
               
               
                 10545.313 
                 Hz 
               
               
                 10639.345 
                 Hz 
               
               
                 10743.118 
                 Hz 
               
               
                 10813.981 
                 Hz 
               
               
                 10832.421 
                 Hz 
               
               
                 10838.243 
                 Hz 
               
               
                 10862.429 
                 Hz 
               
               
                 10865.127 
                 Hz 
               
               
                 10917.229 
                 Hz 
               
               
                 10977.188 
                 Hz 
               
               
                 11120.209 
                 Hz 
               
               
                 11177.289 
                 Hz 
               
               
                 11177.409 
                 Hz 
               
               
                 11321.491 
                 Hz 
               
               
                 11359.093 
                 Hz 
               
               
                 11673.031 
                 Hz 
               
               
                 11793.886 
                 Hz 
               
               
                 11895.229 
                 Hz 
               
               
                 12074.531 
                 Hz 
               
               
                 12216.212 
                 Hz 
               
               
                 12253.329 
                 Hz 
               
               
                 12260.933 
                 Hz 
               
               
                 12262.853 
                 Hz 
               
               
                 12292.222 
                 Hz 
               
               
                 12357.353 
                 Hz 
               
               
                 12527.032 
                 Hz 
               
               
                 12755.333 
                 Hz 
               
               
                 12947.311 
                 Hz 
               
               
                 13717.221 
                 Hz 
               
               
                 13825.295 
                 Hz 
               
               
                 13829.195 
                 Hz 
               
               
                 14410.949 
                 Hz 
               
               
                 14436.201 
                 Hz 
               
               
                 14537.218 
                 Hz 
               
               
                 14947.184 
                 Hz 
               
               
                 15429.139 
                 Hz 
               
               
                 15443.309 
                 Hz 
               
               
                 15450.183 
                 Hz 
               
               
                 16144.343 
                 Hz 
               
               
                 17932.432 
                 Hz 
               
               
                 17951.395 
                 Hz 
               
               
                 17970.122 
                 Hz 
               
               
                 18337.222 
                 Hz 
               
               
                 18378.321 
                 Hz 
               
               
                 18921.415 
                 Hz 
               
               
                 18926.951 
                 Hz 
               
               
                 18931.327 
                 Hz 
               
               
                 114508.332 
                 Hz 
               
               
                   
               
             
          
         
       
     
       Example 4 
     AM Frequencies Employed for Treatment of Prostate Cancer (183 Frequencies so Far Included) 
       [0083]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                   331.3 Hz 
               
               
                  331.358 Hz 
               
               
                  403.218 Hz 
               
               
                  461.233 Hz 
               
               
                   522.2 Hz 
               
               
                  522.213 Hz 
               
               
                   618.4 Hz 
               
               
                  618.407 Hz 
               
               
                   618.8 Hz 
               
               
                  656.295 Hz 
               
               
                  657.394 Hz 
               
               
                  657.397 Hz 
               
               
                   657.4 Hz 
               
               
                  657.483 Hz 
               
               
                  659.033 Hz 
               
               
                   694.4 Hz 
               
               
                  694.689 Hz 
               
               
                   694.7 Hz 
               
               
                   741.4 Hz 
               
               
                  741.421 Hz 
               
               
                  749.221 Hz 
               
               
                   752.9 Hz 
               
               
                  752.933 Hz 
               
               
                  776.194 Hz 
               
               
                  785.219 Hz 
               
               
                  786.332 Hz 
               
               
                  793.331 Hz 
               
               
                  809.205 Hz 
               
               
                  819.322 Hz 
               
               
                   844.8 Hz 
               
               
                  844.822 Hz 
               
               
                  847.332 Hz 
               
               
                 1083.309 Hz 
               
               
                 1102.635 Hz 
               
               
                  1102.71 Hz 
               
               
                 1240.336 Hz 
               
               
                 1372.934 Hz 
               
               
                 1444.288 Hz 
               
               
                 1486.322 Hz 
               
               
                 1563.332 Hz 
               
               
                 1591.322 Hz 
               
               
                 1670.699 Hz 
               
               
                 1697.321 Hz 
               
               
                 1743.521 Hz 
               
               
                 2031.448 Hz 
               
               
                 2050.282 Hz 
               
               
                 2076.519 Hz 
               
               
                 2156.332 Hz 
               
               
                 2229.515 Hz 
               
               
                 2243.121 Hz 
               
               
                 2381.443 Hz 
               
               
                 2440.489 Hz 
               
               
                 2475.912 Hz 
               
               
                 2477.919 Hz 
               
               
                 2628.324 Hz 
               
               
                 2669.328 Hz 
               
               
                 2824.832 Hz 
               
               
                 2887.829 Hz 
               
               
                 2891.331 Hz 
               
               
                 3081.523 Hz 
               
               
                 3249.529 Hz 
               
               
                 3250.125 Hz 
               
               
                 3251.815 Hz 
               
               
                 3264.827 Hz 
               
               
                 3278.329 Hz 
               
               
                 3281.432 Hz 
               
               
                 3348.783 Hz 
               
               
                 3519.118 Hz 
               
               
                 3539.962 Hz 
               
               
                 3551.318 Hz 
               
               
                 3556.439 Hz 
               
               
                 3572.321 Hz 
               
               
                 3670.129 Hz 
               
               
                 3681.341 Hz 
               
               
                 3686.021 Hz 
               
               
                 3753.382 Hz 
               
               
                 3774.923 Hz 
               
               
                 3867.692 Hz 
               
               
                 3909.333 Hz 
               
               
                 3916.321 Hz 
               
               
                 4031.233 Hz 
               
               
                 4031.933 Hz 
               
               
                 4038.203 Hz 
               
               
                 4081.743 Hz 
               
               
                 4084.319 Hz 
               
               
                 4139.322 Hz 
               
               
                 4153.192 Hz 
               
               
                 4223.795 Hz 
               
               
                 4231.221 Hz 
               
               
                 4241.321 Hz 
               
               
                 4320.513 Hz 
               
               
                 4329.152 Hz 
               
               
                 4380.321 Hz 
               
               
                 4417.312 Hz 
               
               
                 4489.452 Hz 
               
               
                 4549.808 Hz 
               
               
                 4558.306 Hz 
               
               
                 4638.293 Hz 
               
               
                 4740.322 Hz 
               
               
                 4854.318 Hz 
               
               
                 4882.322 Hz 
               
               
                 4978.822 Hz 
               
               
                 5237.152 Hz 
               
               
                 5264.222 Hz 
               
               
                 5289.195 Hz 
               
               
                 5426.323 Hz 
               
               
                 5431.542 Hz 
               
               
                 5455.593 Hz 
               
               
                 6345.332 Hz 
               
               
                 6347.433 Hz 
               
               
                 6363.284 Hz 
               
               
                 6418.331 Hz 
               
               
                 6496.231 Hz 
               
               
                 6538.295 Hz 
               
               
                 6577.421 Hz 
               
               
                 6590.328 Hz 
               
               
                 6651.276 Hz 
               
               
                 6706.431 Hz 
               
               
                 6743.322 Hz 
               
               
                 6783.282 Hz 
               
               
                 6850.197 Hz 
               
               
                 6855.286 Hz 
               
               
                 6864.896 Hz 
               
               
                 6871.943 Hz 
               
               
                 6973.393 Hz 
               
               
                 7120.932 Hz 
               
               
                 7146.509 Hz 
               
               
                 7192.505 Hz 
               
               
                 7251.309 Hz 
               
               
                 7251.322 Hz 
               
               
                 7278.124 Hz 
               
               
                 7279.335 Hz 
               
               
                 7299.119 Hz 
               
               
                 7527.229 Hz 
               
               
                 7589.925 Hz 
               
               
                 7699.193 Hz 
               
               
                 7842.184 Hz 
               
               
                  8023.32 Hz 
               
               
                 8096.939 Hz 
               
               
                 8245.801 Hz 
               
               
                 8315.291 Hz 
               
               
                 8357.305 Hz 
               
               
                 8408.121 Hz 
               
               
                 8432.209 Hz 
               
               
                 8535.238 Hz 
               
               
                 8552.431 Hz 
               
               
                 8585.224 Hz 
               
               
                 8935.752 Hz 
               
               
                 9015.253 Hz 
               
               
                 9018.233 Hz 
               
               
                 9068.231 Hz 
               
               
                 9137.232 Hz 
               
               
                 9156.321 Hz 
               
               
                 9351.931 Hz 
               
               
                 9393.946 Hz 
               
               
                 9694.179 Hz 
               
               
                 9984.405 Hz 
               
               
                 10226.223 Hz  
               
               
                 10390.232 Hz  
               
               
                 10514.768 Hz  
               
               
                 10689.339 Hz  
               
               
                 10772.419 Hz  
               
               
                 10818.452 Hz  
               
               
                 11165.239 Hz  
               
               
                 11985.353 Hz  
               
               
                 12209.329 Hz  
               
               
                 12308.321 Hz  
               
               
                 12583.339 Hz  
               
               
                 13820.329 Hz  
               
               
                 14013.123 Hz  
               
               
                 14171.434 Hz  
               
               
                 14681.329 Hz  
               
               
                 14759.131 Hz  
               
               
                 14986.794 Hz  
               
               
                 15930.249 Hz  
               
               
                 16026.623 Hz  
               
               
                 17880.954 Hz  
               
               
                 18247.532 Hz  
               
               
                 18282.211 Hz  
               
               
                 18629.328 Hz  
               
               
                 19469.318 Hz  
               
               
                 19766.218 Hz  
               
               
                 60317.352 Hz  
               
               
                   
               
             
          
         
       
     
       Example 5 
     AM Frequencies Employed for Treatment of Kidney Cancer (36 Frequencies so Far Included) 
       [0084]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  628.321 Hz 
               
               
                  631.141 Hz 
               
               
                  643.312 Hz 
               
               
                  812.512 Hz 
               
               
                  826.321 Hz 
               
               
                 1372.934 Hz 
               
               
                 2082.241 Hz 
               
               
                 2156.931 Hz 
               
               
                 2254.329 Hz 
               
               
                 3555.209 Hz 
               
               
                 3928.343 Hz 
               
               
                 4420.932 Hz 
               
               
                 4819.228 Hz 
               
               
                 4828.321 Hz 
               
               
                 5314.322 Hz 
               
               
                 6007.332 Hz 
               
               
                 7054.279 Hz 
               
               
                 7074.429 Hz 
               
               
                 7254.343 Hz 
               
               
                 8041.289 Hz 
               
               
                 8727.224 Hz 
               
               
                 8760.983 Hz 
               
               
                 8831.132 Hz 
               
               
                 8870.228 Hz 
               
               
                 10565.321 Hz  
               
               
                 10586.229 Hz  
               
               
                 10634.293 Hz  
               
               
                 10687.949 Hz  
               
               
                 11421.933 Hz  
               
               
                 11523.212 Hz  
               
               
                 11561.221 Hz  
               
               
                 11846.212 Hz  
               
               
                 12631.331 Hz  
               
               
                 12693.272 Hz  
               
               
                 14411.321 Hz  
               
               
                 20178.941 Hz  
               
               
                   
               
             
          
         
       
     
       Example 6 
     AM Frequencies Employed for Treatment of Thyroid Cancer (110 Frequencies so Far Included) 
       [0085]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  493.442 Hz 
               
               
                  517.202 Hz 
               
               
                  618.927 Hz 
               
               
                  621.321 Hz 
               
               
                  648.252 Hz 
               
               
                  663.407 Hz 
               
               
                  821.202 Hz 
               
               
                  874.341 Hz 
               
               
                  914.429 Hz 
               
               
                  941.311 Hz 
               
               
                  983.429 Hz 
               
               
                 1587.811 Hz 
               
               
                 1723.389 Hz 
               
               
                 2179.231 Hz 
               
               
                 2315.888 Hz 
               
               
                 2341.312 Hz 
               
               
                 2445.123 Hz 
               
               
                 2454.232 Hz 
               
               
                 2723.302 Hz 
               
               
                 2740.384 Hz 
               
               
                 2749.323 Hz 
               
               
                 2856.253 Hz 
               
               
                 2859.495 Hz 
               
               
                 2886.232 Hz 
               
               
                 3021.122 Hz 
               
               
                 3078.275 Hz 
               
               
                 3080.592 Hz 
               
               
                 3198.323 Hz 
               
               
                 3248.321 Hz 
               
               
                 3271.329 Hz 
               
               
                 3284.192 Hz 
               
               
                 3335.332 Hz 
               
               
                 3434.911 Hz 
               
               
                 3440.212 Hz 
               
               
                 3475.216 Hz 
               
               
                 3509.522 Hz 
               
               
                 3533.328 Hz 
               
               
                 3637.085 Hz 
               
               
                 3682.489 Hz 
               
               
                 4154.301 Hz 
               
               
                 4243.393 Hz 
               
               
                 4261.228 Hz 
               
               
                 4330.289 Hz 
               
               
                 4340.833 Hz 
               
               
                 4358.333 Hz 
               
               
                 4366.294 Hz 
               
               
                 4426.387 Hz 
               
               
                 4458.339 Hz 
               
               
                 4479.113 Hz 
               
               
                 4744.424 Hz 
               
               
                 4865.421 Hz 
               
               
                 5323.192 Hz 
               
               
                 5324.123 Hz 
               
               
                 5548.879 Hz 
               
               
                 5711.283 Hz 
               
               
                 5754.332 Hz 
               
               
                 6455.131 Hz 
               
               
                 6620.132 Hz 
               
               
                 6666.839 Hz 
               
               
                 6714.189 Hz 
               
               
                 6745.333 Hz 
               
               
                 6766.281 Hz 
               
               
                 6884.432 Hz 
               
               
                 7036.122 Hz 
               
               
                 7230.838 Hz 
               
               
                 7323.209 Hz 
               
               
                 7355.378 Hz 
               
               
                 7432.143 Hz 
               
               
                 7534.221 Hz 
               
               
                 7623.184 Hz 
               
               
                 7725.339 Hz 
               
               
                 7920.879 Hz 
               
               
                 8013.953 Hz 
               
               
                 8019.912 Hz 
               
               
                 8040.231 Hz 
               
               
                 8078.955 Hz 
               
               
                 8082.173 Hz 
               
               
                  8147.1 Hz 
               
               
                 8281.259 Hz 
               
               
                 8309.752 Hz 
               
               
                 8311.371 Hz 
               
               
                 8435.094 Hz 
               
               
                 8525.789 Hz 
               
               
                 8744.527 Hz 
               
               
                 9009.329 Hz 
               
               
                 9070.809 Hz 
               
               
                 10020.521 Hz  
               
               
                 10039.109 Hz  
               
               
                 10127.279 Hz  
               
               
                 10134.161 Hz  
               
               
                 10257.324 Hz  
               
               
                 10498.339 Hz  
               
               
                 11537.292 Hz  
               
               
                 11559.292 Hz  
               
               
                 11913.222 Hz  
               
               
                 11927.934 Hz  
               
               
                 11955.949 Hz  
               
               
                 12120.049 Hz  
               
               
                 12139.222 Hz  
               
               
                 13636.082 Hz  
               
               
                 13654.272 Hz  
               
               
                 13677.211 Hz  
               
               
                 14014.941 Hz  
               
               
                 14445.214 Hz  
               
               
                 16023.119 Hz  
               
               
                 16048.391 Hz  
               
               
                 17323.196 Hz  
               
               
                 17577.221 Hz  
               
               
                 17881.709 Hz  
               
               
                 17911.323 Hz  
               
               
                   
               
             
          
         
       
     
       Example 7 
     AM Frequencies Employed for Treatment of Bladder Cancer (28 Frequencies so Far Included) 
       [0086]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  623.243 Hz 
               
               
                  757.084 Hz 
               
               
                   870.4 Hz 
               
               
                 2454.423 Hz 
               
               
                 2480.191 Hz 
               
               
                 2581.101 Hz 
               
               
                 2715.232 Hz 
               
               
                 3042.012 Hz 
               
               
                 3196.194 Hz 
               
               
                 3265.323 Hz 
               
               
                 3438.109 Hz 
               
               
                 3692.319 Hz 
               
               
                 3952.308 Hz 
               
               
                 5230.227 Hz 
               
               
                 6022.942 Hz 
               
               
                 6061.711 Hz 
               
               
                 6710.899 Hz 
               
               
                 6721.912 Hz 
               
               
                 7181.784 Hz 
               
               
                 7458.209 Hz 
               
               
                  8235.21 Hz 
               
               
                 8749.232 Hz 
               
               
                 9354.812 Hz 
               
               
                 12532.729 Hz  
               
               
                 13467.209 Hz  
               
               
                  13777.9 Hz 
               
               
                 14015.241 Hz  
               
               
                 18524.419 Hz  
               
               
                   
               
             
          
         
       
     
       Example 8 
     AM Frequencies Employed For Treatment of Colon Cancer (100 Frequencies so Far Included) 
       [0087]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                   78.76 Hz 
               
               
                  796.562 Hz 
               
               
                  841.541 Hz 
               
               
                  842.783 Hz 
               
               
                  914.429 Hz 
               
               
                 1162.117 Hz 
               
               
                 1372.207 Hz 
               
               
                 1372.934 Hz 
               
               
                 1718.532 Hz 
               
               
                 2243.169 Hz 
               
               
                 2278.312 Hz 
               
               
                  2286.5 Hz 
               
               
                 2286.519 Hz 
               
               
                 2334.178 Hz 
               
               
                 2423.292 Hz 
               
               
                 2454.423 Hz 
               
               
                 2464.229 Hz 
               
               
                 2598.853 Hz 
               
               
                 2623.048 Hz 
               
               
                 3131.123 Hz 
               
               
                 3161.465 Hz 
               
               
                 3175.313 Hz 
               
               
                 3249.529 Hz 
               
               
                 3363.229 Hz 
               
               
                 3373.892 Hz 
               
               
                 3390.925 Hz 
               
               
                 3409.179 Hz 
               
               
                 3432.274 Hz 
               
               
                 3509.522 Hz 
               
               
                 3531.422 Hz 
               
               
                 3533.328 Hz 
               
               
                 3766.296 Hz 
               
               
                 4040.839 Hz 
               
               
                 4081.022 Hz 
               
               
                 4123.953 Hz 
               
               
                 4146.274 Hz 
               
               
                 4233.822 Hz 
               
               
                 4282.332 Hz 
               
               
                 4318.222 Hz 
               
               
                 4344.082 Hz 
               
               
                 4416.221 Hz 
               
               
                 4481.242 Hz 
               
               
                 4724.263 Hz 
               
               
                 4751.319 Hz 
               
               
                 4755.323 Hz 
               
               
                 4788.485 Hz 
               
               
                 5149.331 Hz 
               
               
                 5217.402 Hz 
               
               
                 5386.212 Hz 
               
               
                 5407.192 Hz 
               
               
                 5426.323 Hz 
               
               
                 5496.434 Hz 
               
               
                 5555.212 Hz 
               
               
                 5572.032 Hz 
               
               
                 5634.933 Hz 
               
               
                 5724.231 Hz 
               
               
                 5758.378 Hz 
               
               
                 5787.342 Hz 
               
               
                 5948.897 Hz 
               
               
                 5967.448 Hz 
               
               
                 5976.825 Hz 
               
               
                 6182.322 Hz 
               
               
                 6292.379 Hz 
               
               
                 6324.493 Hz 
               
               
                 6341.248 Hz 
               
               
                 6471.322 Hz 
               
               
                 6477.218 Hz 
               
               
                 6558.342 Hz 
               
               
                 6855.286 Hz 
               
               
                 7129.843 Hz 
               
               
                 7140.187 Hz 
               
               
                 7162.422 Hz 
               
               
                 7368.222 Hz 
               
               
                 7645.859 Hz 
               
               
                 7829.234 Hz 
               
               
                 7866.229 Hz 
               
               
                 7877.334 Hz 
               
               
                 8013.314 Hz 
               
               
                 8374.942 Hz 
               
               
                 8384.228 Hz 
               
               
                 8408.121 Hz 
               
               
                 8534.111 Hz 
               
               
                 8568.033 Hz 
               
               
                 8573.122 Hz 
               
               
                 9226.222 Hz 
               
               
                  9351.9 Hz 
               
               
                 9737.211 Hz 
               
               
                 9744.193 Hz 
               
               
                 9942.321 Hz 
               
               
                 10301.371 Hz  
               
               
                 10401.515 Hz  
               
               
                 10872.693 Hz  
               
               
                 11220.222 Hz  
               
               
                 11283.378 Hz  
               
               
                 12256.432 Hz  
               
               
                 13749.858 Hz  
               
               
                 15231.548 Hz  
               
               
                 15248.324 Hz  
               
               
                 58191.928 Hz  
               
               
                 60317.352 Hz  
               
               
                   
               
             
          
         
       
     
       Example 9 
     AM Frequencies Employed for Treatment of Pancreas Cancer (166 Frequencies so Far Included) 
       [0088]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                   331.3 Hz 
               
               
                  331.365 Hz 
               
               
                   436.3 Hz 
               
               
                  436.332 Hz 
               
               
                  447.942 Hz 
               
               
                  476.127 Hz 
               
               
                  559.292 Hz 
               
               
                  589.187 Hz 
               
               
                  624.218 Hz 
               
               
                    727 Hz 
               
               
                  734.921 Hz 
               
               
                  809.313 Hz 
               
               
                  845.309 Hz 
               
               
                   870.4 Hz 
               
               
                  963.221 Hz 
               
               
                  1156.79 Hz 
               
               
                    1157 Hz 
               
               
                    1179 Hz 
               
               
                 1360.133 Hz 
               
               
                 1372.207 Hz 
               
               
                 1372.934 Hz 
               
               
                 1804.126 Hz 
               
               
                 1816.221 Hz 
               
               
                 1873.477 Hz 
               
               
                 1967.211 Hz 
               
               
                 1990.482 Hz 
               
               
                 2278.312 Hz 
               
               
                 2315.921 Hz 
               
               
                 2320.315 Hz 
               
               
                 2334.178 Hz 
               
               
                 2381.443 Hz 
               
               
                    2469 Hz 
               
               
                 2477.919 Hz 
               
               
                 2542.221 Hz 
               
               
                 2598.853 Hz 
               
               
                 2647.938 Hz 
               
               
                 2685.081 Hz 
               
               
                 2716.095 Hz 
               
               
                 2721.331 Hz 
               
               
                 2732.231 Hz 
               
               
                 2809.849 Hz 
               
               
                 2823.428 Hz 
               
               
                 2835.332 Hz 
               
               
                 3134.313 Hz 
               
               
                 3241.461 Hz 
               
               
                 3255.219 Hz 
               
               
                 3263.432 Hz 
               
               
                 3286.255 Hz 
               
               
                 3330.935 Hz 
               
               
                 3373.892 Hz 
               
               
                 3438.109 Hz 
               
               
                 3449.219 Hz 
               
               
                 3535.219 Hz 
               
               
                 3549.215 Hz 
               
               
                 3564.419 Hz 
               
               
                 3619.412 Hz 
               
               
                 3622.312 Hz 
               
               
                 3638.432 Hz 
               
               
                 3696.424 Hz 
               
               
                 3943.214 Hz 
               
               
                 3976.929 Hz 
               
               
                 4014.889 Hz 
               
               
                 4041.219 Hz 
               
               
                 4044.195 Hz 
               
               
                 4056.384 Hz 
               
               
                 4085.971 Hz 
               
               
                 4144.592 Hz 
               
               
                 4153.192 Hz 
               
               
                 4161.889 Hz 
               
               
                 4243.393 Hz 
               
               
                 4332.498 Hz 
               
               
                 4341.423 Hz 
               
               
                 4355.327 Hz 
               
               
                 4417.885 Hz 
               
               
                 4422.322 Hz 
               
               
                 4451.297 Hz 
               
               
                 4486.384 Hz 
               
               
                 4558.306 Hz 
               
               
                    4580 Hz 
               
               
                 4685.082 Hz 
               
               
                 4839.589 Hz 
               
               
                 5151.402 Hz 
               
               
                 5209.911 Hz 
               
               
                 5262.282 Hz 
               
               
                 5271.312 Hz 
               
               
                  5387.73 Hz 
               
               
                 5494.928 Hz 
               
               
                 5521.221 Hz 
               
               
                 5573.209 Hz 
               
               
                 5609.382 Hz 
               
               
                 5929.616 Hz 
               
               
                 5948.897 Hz 
               
               
                 5966.112 Hz 
               
               
                 5976.825 Hz 
               
               
                 6064.197 Hz 
               
               
                 6086.256 Hz 
               
               
                 6157.253 Hz 
               
               
                 6215.298 Hz 
               
               
                 6333.917 Hz 
               
               
                 6365.242 Hz 
               
               
                 6558.342 Hz 
               
               
                 6568.278 Hz 
               
               
                 6823.194 Hz 
               
               
                 6853.391 Hz 
               
               
                 6855.286 Hz 
               
               
                 7213.204 Hz 
               
               
                 7228.528 Hz 
               
               
                 7238.232 Hz 
               
               
                 7277.921 Hz 
               
               
                 7280.422 Hz 
               
               
                 7320.494 Hz 
               
               
                 7366.412 Hz 
               
               
                 7534.221 Hz 
               
               
                 7548.713 Hz 
               
               
                 7567.127 Hz 
               
               
                 7620.851 Hz 
               
               
                 7663.209 Hz 
               
               
                 7725.203 Hz 
               
               
                 7852.233 Hz 
               
               
                 7920.879 Hz 
               
               
                 7985.122 Hz 
               
               
                 8008.323 Hz 
               
               
                 8013.312 Hz 
               
               
                 8045.484 Hz 
               
               
                 8242.332 Hz 
               
               
                 8351.622 Hz 
               
               
                 8408.121 Hz 
               
               
                 8455.894 Hz 
               
               
                 8551.231 Hz 
               
               
                 8743.321 Hz 
               
               
                 8789.631 Hz 
               
               
                 8868.809 Hz 
               
               
                 9012.241 Hz 
               
               
                 9028.994 Hz 
               
               
                 9131.232 Hz 
               
               
                 9658.296 Hz 
               
               
                 9663.495 Hz 
               
               
                 9680.737 Hz 
               
               
                 9824.442 Hz 
               
               
                 9942.321 Hz 
               
               
                 10279.122 Hz  
               
               
                 10388.49 Hz 
               
               
                 10438.495 Hz  
               
               
                 10518.311 Hz  
               
               
                 10528.239 Hz  
               
               
                 10582.095 Hz  
               
               
                 10926.111 Hz  
               
               
                 10948.411 Hz  
               
               
                 10955.558 Hz  
               
               
                 11538.193 Hz  
               
               
                 11904.741 Hz  
               
               
                 12255.229 Hz  
               
               
                 12613.341 Hz  
               
               
                 12819.942 Hz  
               
               
                 13674.482 Hz  
               
               
                 13731.322 Hz  
               
               
                 14525.312 Hz  
               
               
                 14537.218 Hz  
               
               
                 14549.331 Hz  
               
               
                 14845.453 Hz  
               
               
                 14944.989 Hz  
               
               
                 15246.315 Hz  
               
               
                 18668.239 Hz  
               
               
                 19321.231 Hz  
               
               
                 19347.208 Hz  
               
               
                 30182.932 Hz  
               
               
                   
               
             
          
         
       
     
       Example 10 
     AM Frequencies Employed for Treatment of Lung Cancer (80 Frequencies so Far Included) 
       [0089]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  304.148 Hz 
               
               
                   694.7 Hz 
               
               
                  694.727 Hz 
               
               
                   708.8 Hz 
               
               
                  708.841 Hz 
               
               
                 1587.811 Hz 
               
               
                 1759.318 Hz 
               
               
                 1873.477 Hz 
               
               
                 2253.704 Hz 
               
               
                 2391.312 Hz 
               
               
                 2454.232 Hz 
               
               
                 2729.929 Hz 
               
               
                 2741.261 Hz 
               
               
                 2761.312 Hz 
               
               
                 2784.491 Hz 
               
               
                 2812.443 Hz 
               
               
                 2855.218 Hz 
               
               
                 2859.495 Hz 
               
               
                 3128.822 Hz 
               
               
                 3139.297 Hz 
               
               
                 3193.212 Hz 
               
               
                 3348.783 Hz 
               
               
                 3360.971 Hz 
               
               
                 3366.311 Hz 
               
               
                 3373.892 Hz 
               
               
                 3440.212 Hz 
               
               
                 3461.322 Hz 
               
               
                 3682.489 Hz 
               
               
                 3727.231 Hz 
               
               
                 3749.882 Hz 
               
               
                 3769.942 Hz 
               
               
                 4131.235 Hz 
               
               
                 4158.393 Hz 
               
               
                 4243.393 Hz 
               
               
                 4347.733 Hz 
               
               
                 4373.411 Hz 
               
               
                 4378.321 Hz 
               
               
                 4416.221 Hz 
               
               
                 4481.242 Hz 
               
               
                 4777.521 Hz 
               
               
                 4798.422 Hz 
               
               
                 4837.241 Hz 
               
               
                 4959.842 Hz 
               
               
                 5013.321 Hz 
               
               
                 5047.523 Hz 
               
               
                 5068.322 Hz 
               
               
                 5371.922 Hz 
               
               
                 5538.432 Hz 
               
               
                 5548.879 Hz 
               
               
                 5679.309 Hz 
               
               
                 5734.143 Hz 
               
               
                 5787.342 Hz 
               
               
                 6445.309 Hz 
               
               
                 6838.434 Hz 
               
               
                 6870.955 Hz 
               
               
                 6879.216 Hz 
               
               
                 7079.411 Hz 
               
               
                 7216.288 Hz 
               
               
                 7376.089 Hz 
               
               
                 7761.289 Hz 
               
               
                 8082.173 Hz 
               
               
                 8281.259 Hz 
               
               
                 8352.189 Hz 
               
               
                 8442.473 Hz 
               
               
                 8773.916 Hz 
               
               
                 8935.752 Hz 
               
               
                 9121.223 Hz 
               
               
                 9181.434 Hz 
               
               
                 9317.913 Hz 
               
               
                 9363.896 Hz 
               
               
                 9736.919 Hz 
               
               
                 9753.321 Hz 
               
               
                 10424.908 Hz  
               
               
                 10452.913 Hz  
               
               
                 10824.609 Hz  
               
               
                 11656.329 Hz  
               
               
                 12748.919 Hz  
               
               
                 15774.291 Hz  
               
               
                 15798.333 Hz  
               
               
                 16510.321 Hz  
               
               
                   
               
             
          
         
       
     
       Example 11 
     AM Frequencies Employed for Treatment of Leiomyosarcoma (36 Frequencies so Far Included) 
       [0090]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  836.923 Hz 
               
               
                  843.181 Hz 
               
               
                 1411.241 Hz 
               
               
                 2073.721 Hz 
               
               
                 2381.443 Hz 
               
               
                 2711.019 Hz 
               
               
                 2911.329 Hz 
               
               
                 3232.185 Hz 
               
               
                 3518.321 Hz 
               
               
                 3544.209 Hz 
               
               
                 3569.219 Hz 
               
               
                 4233.822 Hz 
               
               
                 4241.321 Hz 
               
               
                 4266.591 Hz 
               
               
                 4337.322 Hz 
               
               
                 4424.112 Hz 
               
               
                 4436.111 Hz 
               
               
                  4485.22 Hz 
               
               
                 5545.521 Hz 
               
               
                 5577.841 Hz 
               
               
                 5631.422 Hz 
               
               
                 5696.184 Hz 
               
               
                 6472.098 Hz 
               
               
                 6558.342 Hz 
               
               
                 6651.276 Hz 
               
               
                 7168.892 Hz 
               
               
                 7406.309 Hz 
               
               
                 7452.528 Hz 
               
               
                 7649.209 Hz 
               
               
                 7808.352 Hz 
               
               
                 9040.313 Hz 
               
               
                 9074.294 Hz 
               
               
                 9189.092 Hz 
               
               
                 9484.512 Hz 
               
               
                 9943.972 Hz 
               
               
                 12086.394 Hz  
               
               
                   
               
             
          
         
       
     
       Example 12 
     AM Frequencies Employed for Treatment of Mesothelioma (16 Frequencies so Far Included) 
       [0091]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  958.929 Hz 
               
               
                 1713.913 Hz 
               
               
                 1736.782 Hz 
               
               
                 2334.178 Hz 
               
               
                 2607.193 Hz 
               
               
                 3112.974 Hz 
               
               
                 3319.945 Hz 
               
               
                 3449.219 Hz 
               
               
                 3622.312 Hz 
               
               
                 5151.402 Hz 
               
               
                 5887.022 Hz 
               
               
                 5965.922 Hz 
               
               
                 6516.793 Hz 
               
               
                 7224.197 Hz 
               
               
                 9471.152 Hz 
               
               
                 14617.393 Hz  
               
               
                   
               
             
          
         
       
     
       Example 13 
     AM Frequencies Employed for Treatment of Neuro-Endocrine (30 Frequencies so Far Included) 
       [0092]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                 1766.335 Hz 
               
               
                 2408.225 Hz 
               
               
                 2441.502 Hz 
               
               
                 2647.938 Hz 
               
               
                 2741.261 Hz 
               
               
                 3020.212 Hz 
               
               
                 3128.822 Hz 
               
               
                 3238.742 Hz 
               
               
                 3296.431 Hz 
               
               
                 3348.783 Hz 
               
               
                 3360.971 Hz 
               
               
                 3440.212 Hz 
               
               
                 3533.328 Hz 
               
               
                 3666.283 Hz 
               
               
                 4079.282 Hz 
               
               
                 4243.393 Hz 
               
               
                 4426.387 Hz 
               
               
                 5245.818 Hz 
               
               
                 5536.242 Hz 
               
               
                 5548.879 Hz 
               
               
                 5739.422 Hz 
               
               
                 5849.241 Hz 
               
               
                 6291.631 Hz 
               
               
                 6406.891 Hz 
               
               
                 6780.679 Hz 
               
               
                 7151.264 Hz 
               
               
                 7482.245 Hz 
               
               
                 7575.393 Hz 
               
               
                 8359.932 Hz 
               
               
                 9073.418 Hz 
               
               
                   
               
             
          
         
       
     
       Example 14 
     AM Frequencies Employed for Treatment of Leukemia and Chronic Lymphoid Cancer (17 Frequencies so Far Included) 
       [0093]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  814.413 Hz 
               
               
                  825.145 Hz 
               
               
                 2415.243 Hz 
               
               
                 2436.316 Hz 
               
               
                 2874.432 Hz 
               
               
                 2891.029 Hz 
               
               
                 3361.671 Hz 
               
               
                 5245.452 Hz 
               
               
                 5557.333 Hz 
               
               
                 6850.197 Hz 
               
               
                 6919.322 Hz 
               
               
                 7587.224 Hz 
               
               
                 7629.318 Hz 
               
               
                 8172.405 Hz 
               
               
                 8272.338 Hz 
               
               
                 8438.453 Hz 
               
               
                 12950.331 Hz  
               
               
                   
               
             
          
         
       
     
       Example 15 
     AM Frequencies Employed for Treatment of Myeloma, Multiple Cancer (20 Frequencies so Far Included) 
       [0094]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                  765.196 Hz 
               
               
                 2336.238 Hz 
               
               
                 2372.122 Hz 
               
               
                 2381.443 Hz 
               
               
                 2425.394 Hz 
               
               
                 2656.339 Hz 
               
               
                 2741.261 Hz 
               
               
                 2883.618 Hz 
               
               
                 2919.273 Hz 
               
               
                 3265.323 Hz 
               
               
                 3564.455 Hz 
               
               
                  3580.25 Hz 
               
               
                 3584.291 Hz 
               
               
                 3674.292 Hz 
               
               
                 5249.331 Hz 
               
               
                 7967.311 Hz 
               
               
                 7973.125 Hz 
               
               
                 8049.952 Hz 
               
               
                 8283.329 Hz 
               
               
                 10351.323 Hz  
               
               
                   
               
             
          
         
       
     
       Example 16 
     AM Frequencies Employed for Treatment of Hodgkin Disease (Lymphoma) (19 Frequencies so Far Included) 
       [0095]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                   752.5 Hz 
               
               
                   976.3 Hz 
               
               
                 1558.223 Hz 
               
               
                 2310.912 Hz 
               
               
                 2477.919 Hz 
               
               
                 2560.843 Hz 
               
               
                 3348.783 Hz 
               
               
                 3371.216 Hz 
               
               
                 3605.432 Hz 
               
               
                 3623.198 Hz 
               
               
                 3838.281 Hz 
               
               
                  3838.48 Hz 
               
               
                    5102 Hz 
               
               
                 5696.932 Hz 
               
               
                 5724.231 Hz 
               
               
                 6358.194 Hz 
               
               
                 7472.211 Hz 
               
               
                 8062.121 Hz 
               
               
                 8222.222 Hz 
               
               
                   
               
             
          
         
       
     
       Example 17 
     AM Frequencies Employed for Treatment of Brain Cancer (57 Frequencies so Far Included) 
       [0096]      
         [0000]    
       
         
               
             
           
               
                   
               
             
             
               
                 1372.934 Hz 
               
               
                 2318.182 Hz 
               
               
                 2381.443 Hz 
               
               
                 2425.394 Hz 
               
               
                 2442.423 Hz 
               
               
                 2478.973 Hz 
               
               
                 2654.513 Hz 
               
               
                 2661.324 Hz 
               
               
                 2686.105 Hz 
               
               
                 2690.179 Hz 
               
               
                 3249.332 Hz 
               
               
                 3277.509 Hz 
               
               
                 3335.279 Hz 
               
               
                 3348.783 Hz 
               
               
                 3436.211 Hz 
               
               
                 3916.321 Hz 
               
               
                 4031.933 Hz 
               
               
                 4086.091 Hz 
               
               
                 4241.321 Hz 
               
               
                 4318.222 Hz 
               
               
                  4334.33 Hz 
               
               
                 4358.333 Hz 
               
               
                 4393.419 Hz 
               
               
                 4454.194 Hz 
               
               
                 4515.789 Hz 
               
               
                 4619.324 Hz 
               
               
                 4723.937 Hz 
               
               
                 4853.286 Hz 
               
               
                 5289.231 Hz 
               
               
                 5378.099 Hz 
               
               
                 5426.323 Hz 
               
               
                 5640.981 Hz 
               
               
                 6316.211 Hz 
               
               
                 6459.203 Hz 
               
               
                 6474.332 Hz 
               
               
                 6626.572 Hz 
               
               
                 6855.286 Hz 
               
               
                 6915.886 Hz 
               
               
                 6943.386 Hz 
               
               
                 7151.264 Hz 
               
               
                 7182.922 Hz 
               
               
                 7194.897 Hz 
               
               
                 7323.209 Hz 
               
               
                 7390.343 Hz 
               
               
                 7796.221 Hz 
               
               
                 7961.122 Hz 
               
               
                 8128.942 Hz 
               
               
                 8245.109 Hz 
               
               
                 8272.281 Hz 
               
               
                 8358.154 Hz 
               
               
                 8408.121 Hz 
               
               
                  9138.82 Hz 
               
               
                 10719.318 Hz  
               
               
                 11556.241 Hz  
               
               
                 12828.633 Hz  
               
               
                 14515.962 Hz  
               
               
                 14586.765 Hz  
               
               
                   
               
             
          
         
       
     
         [0097]    The above Examples reflect AM frequencies determined by a bio-feedback procedure involving very substantial observations and measurements of physiological responses (at certain well defined AM frequencies) by subjects exposed to low energy electromagnetic emission excitation. In general, it is recommended that all of the listed frequencies be applied in the treatment of subjects suffering from the indicated form of cancer. However, a limited number of the listed frequencies also lead to beneficial effects. 
         [0098]    Of note in respect of the above listed frequencies, in particular those Examples including a large number of frequencies, it has earlier on been determined that beneficial therapeutic effects are achieved by application of some but not all of the frequencies listed. However, following on more extended trials, it has been determined that application to subjects of further frequencies enhance the efficacy of treatment and yields therapeutic effects in patients whose tumours have become resistant to therapy. It is accordingly preferred that all of the determined listed frequencies be applied to the subject. The mechanism of including additional frequencies is attributed to either or both of inter-active synergism between applied frequencies or between cells which have been influenced by the treatment and additive effects of the additional frequencies. 
         [0099]    Of further note is the fact that different patients suffering from the same type of tumour cell growth practically invariably exhibit the above-mentioned physiological responses at the same well defined AM frequencies. Furthermore, AM frequencies which differ only very slightly (less than 0.0001% at higher frequencies) from the frequencies listed, in general elicit no physiological response by subjects exposed to excitation at such very slightly different frequency. In view of these determinations, the electronic system of the present invention may be adapted to screen a subject for physiological responses over a broad range of frequencies to determine the presence or absence tumour cells and, if positive, then to note at which defined frequencies physiological responses are elicited. These frequencies will in general match with the defined frequencies listed in one or other of the Examples above or such further examples as may be developed and hence the nature of the tumour will be known. The electronic system of the invention is therefore a valuable diagnostic tool for diagnosing the presence or absence and identities of types of tumour cell growths or cancers. Furthermore, the electronic system of the invention is of value for predicting whether a patient will benefit from the application of a given series of modulation frequencies. The system therefore possesses a capability of predicting responses to treatment, thereby enhancing the possibility to select optimal modes of treatment. 
         [0100]    The sequence of well defined frequencies are preferably applied sequentially for determined periods of time, e.g. 3 seconds for each frequency, but several frequencies may also be applied simultaneously. This means that a cycle of application involving 180 frequencies would take nearly 10 minutes time. Advantageous effects may however also arise from applying individual well defined frequencies for differing time periods, e.g. some for 3 seconds, some for 6 seconds, etc. . . . . 
         [0101]    Therapeutic dosages to be applied to a subject suffering from the presence of tumour cell growth or cancer are determined by the time of application of the low energy electromagnetic emissions to the subject and will depend on the nature of the cancer and the overall condition of the subject. In general, however, greatest experience has been gained in treating terminally ill subjects expected to survive no longer than about three months and who have agreed to discontinue alternative forms of cancer treatments such as chemo-therapy or radioactive treatment. In these severe cases, lengthy times of treatment are recommended, e.g. 3 times 1 hour daily treatment. However, with the development of alternative forms of application, i.e. other than by means of a mouth probe, continuous application is possible and is likely to enhance compliance and the efficacy of the treatment. 
         [0102]    While the invention has been described with specific embodiments, other alternatives, modifications, and variations will be apparent to those skilled in the art. Accordingly, it will be intended to include all such alternatives, modifications, and variations within the spirit and scope of the appended claims.