Abstract:
A bag arrangement for intermixing two, separately stored substances. The bag arrangement includes a bag having a jacket defining an inner chamber for accommodating a first substance and a piercing device having a chamber in which the jacket is received. A single piercing member is provided on one side of the jacket and a hollow abutment is located opposite the piercing member on an opposite side of the jacket and forms a receptacle for accommodating a second substance. Upon actuation of the piercing device, the piercing member pierces the opposite sides of the jacket providing for intermixing of the first and second substances.

Description:
BACKGROUND OF THE INVENTION 
     1. Field of the Invention 
     The present invention relates to a bag arrangement including a bag for accommodating a first substance to be inserted, in particular, into the human or animal body and having at least one jacket enclosed on all sides and a piercing device attached to the jacket or to be attached to it, with the piercing device having means for piercing the jacket. 
     2. Description of the Prior Art 
     SUMMARY OF THE INVENTION 
     This and other objects of the present invention, which will become apparent hereinafter, are achieved by providing a bag arrangement of the above describe type in which the a receptacle for accommodating a second substance is formed by the abutment of the piercing device, which is separated from the inner chamber of the bag with the first substance, with the mixing process being started between the first and second substances with or after the piercing device has been actuated. 
     A central idea of the present invention can be seen therein that a receptacle provided on the piercing device is made for accommodating a second substance which is separated vis-à-vis the bag interior or the first substance. The bag is made in such a way that, after the piercing device has been activated, a mixing process is initiated between the first and second substance. 
     The second substance can be present especially in a liquid, solid, powdery gaseous or gelatinous state. It should be especially noted that the first and second substance can, in principle, be the same, so that they can be refilled via the abutment by connection to a filling system or additional bag in the bag actually provided for draining. If a second bag is connected via the abutment and if the first and second substance are present in a liquid state with comparable viscosity, then, surprisingly, a mixing ratio of 50/50 results between the first and second substance in the bag actually tested. Second substances which can only be preserved for a short time in the first substance or which decompose relatively quickly in the first substance can be conveyed via the abutment to the first substance per bag puncture. Examples of secondary substances of this type are live microbiological cultures of sensitive substances such as glutamine or enzymes. 
     A further idea of the invention can be seen in the separating film inserted between the first and second substance, said separating film being perforated at the same time as the bag is punctured. 
     In another advantageous embodiment, the separating film is formed by the jacket of the bag itself, so that the manufacture and mounting of a separate separating film can be omitted. 
     In an actual preferred embodiment, the piercing device comprises a slide-mounted punch for puncturing the at least one jacket as well as an abutment into which the punch sinks when piercing the jacket. 
     Preferably, the receptacle for the second substance is formed by the abutment of the piercing device. Since the abutment is advantageous for mechanical reasons, the second substance to be inserted can be simultaneously accommodated therein. Actuating the piercing device and especially the sinking of the punch of the piercing. device accelerate the mixing process between the first and second substance. 
     In an alternative design, a draining connection is formed on the piercing device or a drain line can be attached thereto, whereby the receptacle is formed on the draining connection or in the drain line. In this embodiment, the mixing process takes place when the bag is being emptied whereas, in the alternatives described above, a first and second substance can also be mixed inside the bag prior to draining said bag. 
     In a possible embodiment, the abutment is only open toward the inside of the bag, however, it is covered with the separating film and otherwise sealed on all sides. In this embodiment, the second substance can already be inserted when manufacturing and assembling the bag or when attaching the piercing device to the jacket of the bag. This alternative design is suitable for second substances which can be preserved by themselves without contact with the first substance, whereby a mixing between first and second substance is desired prior to use of the bag. 
     Preferably, the receptacle is designed to accommodate a single pack containing the active substance provided with a perforable film. An especially cup-shaped abutment can, for example, form the receptacle for a tablet sealed with a film. When the perforable film is punctured, the first substance present in the bag can come into contact with the tablet, so that a desired effect is produced by mixing the first subtance and the second substance (here the tablet), or the second substance is dissolved. 
     Just when the first substance is present in liquid form, the piercing device can be provided with means that promote the flow of the liquid substance into the receptacle. This can, in particular, be attained thereby that the piercing device has a punch with cutting ribs, whereby the cutting ribs convey the liquid into the receptacle. 
     Alternatively to the design of the receptacle open to the bag interior, the receptacle can also have a further opening, preferably at its end facing away from the bag. This opening can be sealed by a protective cover or a protective film. When the protective cover is removed or the protective film perforated, a second or supplementary bag or a substance cartridge can be attached or the liquid drawn off. This design offers numerous additional application possibilities for the bag. 
     First, the connection of supplementary bags or bag systems or refilling devices will be considered. In this case, for example, the first substance in the bag to be drained could be diluted separately depending on the application. As already discussed above, a very constant mixing ratio of 50/50 results surprisingly in the configuration tested. This could be verified both via density measurements and via chloride ion determinations so as to be reproducible. To this end, 500 ml of a first substance in the bag were mixed with an additional 500 ml diluent as a second substance in the intermediate bag space. 
     In particular when administering nutrients from the bag, a complete diet can be put together with different substances by connecting supplementary bags, whereby these substances can be administered either simultaneously, staggered in time or in succession, without it being necessary to make any changes in the feeding devices between the first bag and the patient. 
     In an especially preferred embodiment, a substance cartridge can be attached to the receptacle. In this case also, we can keep the administration of nutrients in mind, whereby special active substances, additives, medicine or the like can be contained in the substance cartridge. With a bag of the proposed design, it is possible to add a suitable substance cartridge, or one prescribed by the doctor, to a first substance as basic substance depending on the individual patient&#39;s specific requirements. With respect to the possible designs for the substance cartridge which is attachable to the bag so as to be largely germ-free, reference is made to the actual embodiments described below. 
     Advantageously, for a largely germ-free attachment, the opening of the receptacle provided for the protective cartridge is covered with a protective film, whereby this protective film is cut through when the substance cartridge is inserted. 
     In an actual design, the substance cartridge can be either pushed onto the receptable or into the receptacle, whereby a seal between the substance cartridge and receptacle is ensured by at least one circumferential projection between substance cartridge and receptacle. The volume of the substance cartridge can be adapted to the volume of the receptacle. To increase the fill volume of the substance cartridge, however, an expansion outward is provided. In an actual design, this expansion is obtained at maximum in the form of a second bag that can be directly attached. 
     When both the substance cartridge and the receptacle have a circumferential projection, then they can first pass one another when they have a corresponding structural design when the substance cartridge is being slipped on or in, so that a mechanical interlocking results. The circumferential projections or protective cartridge and receptacle themselves are each made flexible in such a way that, in spite of this interlocking possibility, a sufficient seal is assured between substance cartridge and abutment. In an alternative design, a draining connection can also be formed on the receptacle on the side facing away from the bag. A substance can then be supplied or removed directly from the bag via the receptacle. This idea is claimed independent of the idea for inserting a second substance or mixing a first and second substance. 
     In a further special design, the piercing device, in particular, the operating piston of the piercing device also has a connection for attaching a connecting or drain line. For this purpose, a liquid outlet is provided between the operating piston and punch, so that a substance can be inserted into the bag or removed from the bag via the punch. This ides is also claimed independent of inserting a second substance and independent of the design of a draining connection on the receptacle. When connections are provided both on the operating piston and on the receptacle, an inlet and outlet can be simultaneously provided for a bag in a simple manner. 
    
    
     BRIEF DESCRIPTION OF THE DRAWINGS 
     The invention shall be described in greater detail in the following, also with respect to further features and advantages, with reference to the description of examples of embodiments and with reference to the attached drawings, showing: 
     FIGS. 1 a  to  1   d  a first embodiment of a bag according to the invention having a second substance located in the abutment, whereby the piercing device is shown in the initial position (FIG. 1 a ), immediately prior to perforation of the jacket (FIG. 1 b ), after perforation of jacket and separating film (FIG. 1 c ) and after activating the piercing device and starting a mixing process between a first and second substance (FIG. 1 d ), 
     FIG. 2 a  an embodiment of a plate bar with piercing device in the open state in a top view, 
     FIG. 2 b  the plate bar with piercing device of FIG. 2 a  along the line IIb, IIb, 
     FIG. 3 a  a partial sectional view of the piercing device, 
     FIG. 3 b  the piercing device along the line IIIb, IIIb in FIG. 3 a,    
     FIG. 3 c  a sectional view of the piercing device along the line IIIc IIIc in FIG. 1 b,    
     FIG. 3 d  the draining connection along the line IIId, IIId in FIG. 2 a,    
     FIG. 4 a  an embodiment of a substance cartridge that can be mounted on an abutment prior to assembly, 
     FIG. 4 b  the substance cartridge slipped onto the abutment from FIG. 4 a;    
     FIG. 5 a  an embodiment of a substance cartridge that can be inserted into the abutment prior to being inserted, 
     FIG. 5 b  the substance cartridge inserted into the abutment, 
     FIG. 5 c  the bag according to FIG. 5 a  with inserted substance cartridge when actuating the piercing device prior to perforation of the jacket, 
     FIG. 5 d  the bag of FIG. 5 a  when actuating the piercing device after perforation of the jacket as well as after perforation of the separating film between a first and second substance, 
     FIG. 5 e  the bag of FIG. 5 a  with piercing device and substance cartridge inserted into the abutment after mixing first and second substance, 
     FIG. 6 an embodiment for an intermediate piece which can be inserted between a drain line and the abutment and with a second substance, 
     FIG. 7 an embodiment in which a number of supplementary bags are coupled to the abutment of a first bag, 
     FIG. 8 a  an alternative embodiment of a plate bar with piercing device, in a sectional view, 
     FIG. 8 b  the plate bar with piercing device from FIG. 8 a , in a top view, FIG. 8 c  a partial sectional view of a piercing device for use on a plate bar according to FIG. 8 a  and FIG. 8 b.   
    
    
     DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS 
     A first embodiment of the bag arrangement with a second substance  51  situated in a receptacle  10  is shown in FIGS. 1 a  to  1   d . FIGS. 1 a  to  1   d  show the piercing device  12  in various positions, to illustrate its mode of operation. In this concrete embodiment, the piercing device  12  is welded onto the outer jacket  11  of a bag  15 . A further inner jacket  27 , sealed on all sides and in which a first substance  50  is packed so as to be germ-free, is found in the bag  15  shown here. 
     The piercing device  12  comprises a plate bar  30  on which a front plate  31  and a rear plate  32  are formed. The plate bar  30  forms a film hinge  39  between the front plate  31  and the rear plate  32 . The front plate  31  of the plate bar  30  is welded to a first side of the jacket  11  and the rear plate  32  to an opposite side of the jacket  11  of the bag  15 . The front plate  31  and rear plate  32  of the plate bar can come approach one another by means of the film hinge  39  by pressing the allocated bag corner or bag edge together. 
     In the area of the front plate  31 , a punch  13  of the piercing device  12  is slide-mounted essentially at right angles to the plane of the front plate  31  in a cylindrical guide  28 . An operating piston  29  for actuating the punch  13  is found at the end on the punch  13 . Operating piston  29  or punch  13  are mounted so as to seal against the cylindrical guide  28 , so that both the escape of a substance from the bag  15  and the entry of germs into the bag  15  is prevented. 
     In the area of the rear plate  32  of the plate bar  30 , an abutment  14  is formed into which the punch  13  can enter when the piercing device  12  is actuated. The abutment  14  forms the receptacle  10 . At the same time, according to the invention, the second substance  51  is accommodated in the abutment  14 , said second substance  51  being insulated with a separating film  16  vis-à-vis the bag  15  interior. 
     When the piercing device  12  is actuated, the front plate  31  and rear plate  32  of the plate bar  30  are first pressed together, for example, thereby that operating piston  29  and abutment  14  are gripped between the thumb and index finger. 
     As can be seen in FIG. 1 b , the abutment  14  is placed directly opposite the punch  13 . If further pressure is now exerted on abutment  14  and operating piston  29 , then punch  13  punctures the front side of jacket  11 , twice through the inner jacket  27  and again on the rear through jacket  11  and perforates them. Alternatively, corresponding recesses can be provided on the front and/or rear in the outer jacket  11 , so that a perforation of the outer jacket  11  is unnecessary. After perforation of the jacket(s) of the bag  15 , according to the invention, the punch  13  also passes through a separating film  16  which covers the abutment  14  and insulates a second substance  51  from the interior of the bag  15 . After this perforation (FIG. 1 d ), the second substance  51  can mix with the first substance  50  packed in the bag. In the embodiment shown, the first subtance  50  also does not reach into the area between inner jacket  27  and outer jacket  11  of bag  15  until the inner jacket  27  is perforated. 
     If a liquid substance is used as first substance  50 , then there is a further advantage of the double bag actually shown. 
     When the bag  15  is suspending properly, the liquid first substance  50  flows out of the inner bag restricted by inner jacket  27  into the area between inner jacket  27  and outer jacket  11 . This flowing out takes place, in part, via the area of the punch  13  of the piercing device. The punch  13  has cutting ribs  17  arranged crosswise, extending essentially parallel to the direction of piercing. The cutting ribs  17  convey the liquid first substance  50  into the area of the abutment  14 , so that a second substance  51  found there is rinsed out properly after perforation of the separating film  16  and mixes surprisingly homogeneously with the first substance  50 . The aforementioned “rinsing out” is extremely helpful when the second substance  51  is powdery or in form of a tablet. 
     With reference to FIGS. 2 a  and  2   b , the piercing device  12  will be described in greater detail in the following. In FIG. 2 a , the plate bar  30  is shown in the open state. The abutment  14 , made as one piece with the plate bar  30 , is arranged on the rear plate  32 . On the opposite side, the cylindrical guide  28  is also made in one piece with the plate bar  30  at a corresponding location on the front plate  31 . The cylindrical guide  28  has two guide ribs  33  that correspond with corresponding grooves  34  in the operating piston  29 . 
     Furthermore, on the front plate  31 , a draining connection  35  is formed which has an outer connecting piece  37  and, concentrically thereto, an inner connecting piece  56 . The inner connecting piece  36  is provided as a pipe socket for conveying out the first and second substance  50 ,  51  packed in the bag. The outer connecting piece  37  has an internal thread  38 , so that a drain line  46  can be preferably connected via a Luer connection. The film hinge  39 , already mentioned, is formed between the front plate  31  and rear plate  32  on the plate bar  30 , said film hinge  39  being substantially thinner than the front and rear plate  31 ,  32 . Front plate  31  and rear plate  32  are, furthermore, surrounded by film edges  52 ,  53 . The plate bar  30  can be welded to. the outer jacket  11  of bag  15  via the film edges  52 ,  53 . 
     The piercing device IIb, IIb in FIG. 2 a  is shown in FIG. 2 b . Essentially true to scale are the various thicknesses between the front plate  31  and rear plate  32 , on the one hand, and the film hinge  39 , on the other hand. It should be pointed out that the guide ribs  33 , do not extend over the entire length of the cylindrical guide  28 , so that the operating piston  29  can be turned relative to the cylindrical guide  28  in its initial and rest position. Only when the grooves  34  provided in the operating piston correspond to the guide ribs  33 , the operating piston  29  and with it the punch  13  can be pressed in, so that an unintentional perforation of the bag is made more difficult. It should also be noted that an interlocking is effective between cylindrical guide  28  and operating piston  29 , such that the operating piston  29  is ensured against falling off from the cylindrical guide  28 . 
     In FIG. 3 a , the actual arrangement between the cylindrical guide  28  and the operating piston  29  as well as the punch  13  is shown in a sectional view. The operating piston  29  has a central middle recess  54  that enters into the cylindrical guide  28  and slides along the cylindrical guide  28  on the inside. Between the recess  54  of the operating piston  29  and the cylindrical guide  28 , a surround seal is effective which prevents a substance from escaping from the bag  15  or germs or contaminants from entering the bag  15 . The punch  13  is arranged inside the operating piston  29  below recess  54 , said punch  13  having two cuttings ribs  17  extending crosswise to one another. 
     A sectional view of the cylindrical guide  28  and the operating piston  29  along the line IIIb, IIIb in FIG. 3 a  is shown in FIG. 3 b . In the position shown, the guide ribs  33  of the cylindrical guide  28  correspond with the grooves  54  of the operating piston  29 , so that the punch  13  can be shifted in the piercing device. 
     In FIG. 3 c , a sectional view of the punch  13  mounted so as to be slidable in the cylindrical guide  28  is shown. The alignment of the operating piston  29  and thus the punch  13  with its cutting ribs  17  can be determined by the guide ribs  33  provided on the cylindrical guide  28 , so that conditions can be created that are always reproducible for the perforation of the jacket(s) as well as the separating film  16  and for the inlet of the first substance  50 . 
     The draining connection  35  from FIG. 2 a  is shown in FIG. 3 d  in a sectional view along the line IIId, IIId. The internal thread  38  in the outer connecting piece  37  can be clearly seen. The inner connection piece  36  is longer than the outer connecting piece  37  and protrudes on the end facing away from the front plate  31 . 
     In FIGS. 4 a  and  4   b , an embodiment of a substance cartridge  20  that is mountable on the abutment  14  is shown. In this embodiment, the abutment  14  has an opening  21  on its end facing away from the bag  15 . The opening  21  can be sealed with a protective cover. The protective cover can, for example, be made like a removable cover, preferably, however, a protective film  23  is provided which seals the opening  21  so as to be germ-free. 
     The substance cartridge  20  according to this embodiment comprises an inner chamber  61  in which the second substance  51  is housed. On the outside, the substance cartridge  20  is limited by a hat-shaped cap  58  inside which the chamber  61  is located. The chamber  61  is limited by a wall  59 , a part of the inner side of the hat-shaped cap  58  as well as by a protective film  18 . The protective film  18  houses the second substance  51  and protects against contaminations and germs. When the protective cartridge  20  is placed on the abutment  14 , this protective film  18  is also cut through. 
     To perforate the protective film  18  of the substance cartridge  20  and the protective film  13  of the abutment  14 , a punch  41  a is centrally arranged inside the chamber  61  of the substance cartridge  20 , the tip of said punch  41  being slightly spaced from the protective film  18  of the substance cartridge  20 . As soon as the substance cartridge  20  is placed on the abutment  14 , the protective film  18  is thereby lightly pressed inward and finally on the punch  41  a, so that the protective film  18  is cut through. At the same time, the now exposed punch  41  a acts on the protective film  23  of the abutment  14  and also cuts through it, so that the chamber  61  already inserted into the abutment  14  enables a germ-free passage of the second substance  51  into the abutment  14 . 
     The chamber  61  has an outer cross section corresponding to the inner cross section of the abutment  14  which is, however, dimensioned slightly smaller, so that the chamber  61  can be pushed into the abutment  14 . Chamber  61  and abutment  14  can have an essentially circular cross section, an oval, rectangular cross section or a cross section of another shape. 
     The inner cross section of the hat-shaped cap  58  can also be adapted to the outer cross section of the abutment in an appropriate manner. 
     Seals are preferably provided between the inner wall of the abutment  14  and the chamber  61 . The seals are advantageously arranged in such a way that they pass one another when being mounted and thus ensure a locking of the chamber  61  or the substance cartridge  20  on the abutment  14 . Alternatively, seals can also be provided between the outer side of the abutment  14  and the inner side of the hat-shaped cap  58 , whereby a locking of the substance cartridge  20  on the abutment  14  can also be simultaneously obtained when the seals are designed appropriately. 
     In FIGS. 5 a  to  5   e , a third alternative embodiment of a substance cartridge  20  is shown for coupling to the abutment  14 . Contrary to what is shown in FIGS. 4 a  and  4   b , the substance cartridge  20  is here made for insertion into the abutment  14 . 
     As can be seen in FIG. 5 a , the abutment  14  is open at its two ends and thereby covered with a separating film  16  toward the bag interior and with a protective film  23  to the end facing away from the bag  15 . 
     The substance cartridge  20  has an outer cross section corresponding to the inner cross section of the abutment  14 . The substance cartridge  20  can have a circular, oval, rectangular cross section or a cross section of another shape. The substance cartridge  20  itself is covered with a protective film  18  on its front side in direction of insertion. 
     As can be seen in FIG. 5 b , the protective film  23  of the abutment  14  perforated when the substance cartridge is pushed in. In this embodiment also, the substance cartridge  20  as well as abutment  14  has circumferential seals at each of the surfaces facing one another, said seals preventing the substance from escaping bag  15  or from escaping from the substance cartridge  20  or germs from entering the abutment  14 . The seals are, moreover, advantageously made in such a way that they pass one another when being inserted and thus ensure that the substance cartridge  20  is locked in the abutment  14 . 
     FIGS. 5 c ,  5   d  and  5   e  illustrate the actuating of the piercing device  12  when a substance cartridge  20  has been inserted. The punch  13  of the piercing device  12  can, in this embodiment, also cut through the separating film  16  on the abutment  14  as well as the protective film  18  of the substance cartridge in addition to the perforation of jackets  11  and  27 , so that the second substance  51  found in the substance cartridge  20  can reach inside the bag  15  and mix there with the first substance  50 . 
     In FIG. 6, an intermediate piece  40  is shown in a diagrammatic sketch. The intermediate piece  40  can be connected to the abutment  14  for draining or filling the bag  15 . For this purpose, the intermediate piece  40  has on its end provided for connection to the abutment  14  an adapter  55  which can be mounted on the abutment  14  in a manner similar to the one shown in FIGS. 4 a  and  4   b  for the substance cartridge  20 . Prior to use, the adapter  55  is covered with a protective film  18  on its end. Inside the adapter  55  and covered by the protective film  18 , there is a punch  41   b  that cuts through both the protective film  18  of the adapter and the protective film  23  of the abutment  14  when pressing the adapter  55  onto the abutment  14 . 
     At its opposite end, a further connection  22  can be provided on the intermediate piece  40 , said connection  22  being made in a manner corresponding to the draining connection  35  shown in FIG. 3 d . Between the adapter  55  as the one end of the intermediate piece and a connection on the other end extends a connecting line  47  which can be made as a straight connecting line having a uniform cross section. In the present case, however, an expansion  42  is provided in the connecting line  47  as receptacle  10  for the second substance in which a predetermined volume of a second substance  51  is housed. The bag  15  can be drained with an intermediate piece of this type provided with a second substance  51  and the second substance  51  thereby rinsed out directly by means of the first substance  50  of the bag  15  when it flows through. 
     An embodiment is shown in FIG. 7 in which a number of supplementary bags  43 ,  44 ,  45  are connected in series to the abutment  14  of the bag  15 . For example, via the intermediate piece  40  described with reference to FIG. 6 in which the expansion  52  provided for accommodating the second substance  51  does not have to be provided, a supplementary bag  43  having its draining connection  35  on the abutment  14  of the bag  15  can be attached. As a result, almost any number of bags  15  desired can be coupled together, so that a drain line  46  leading e.g. to the patient can be permanently left between the patient and the bag  15 . The supplementary bags  43 ,  44 ,  45  can be provided as a “refill pack” for bag  15 . A diluting of the first substance  50  in bag  15  can also be obtained with an supplementary bag  43 . 
     Furthermore, by connecting one or more supplementary bags  43 ,  44 ,  45 , a complete diet can be put together for a patient, whereby the supplementary bags  43 ,  44 ,  45  can be drained simultaneously, staggered in time or in succession. The arrangement shown in FIG. 7 is purely schematical and is to illustrate the connection in series of several bags, whereby the number of bags can be arranged horizontally to one another, vertically or in any other position desired. 
     An alternative embodiment of a plate bar with a piercing device  12  is shown in FIGS. 8 a  and  8   b . In the embodiment shown in FIGS. 8 a  and  8   b , the draining connection  35  is formed directly on the side facing away from the plate bar  30  to the abutment  14 . As a result, substance can be supplied to the bag  15  or removed from it via the abutment. 
     In FIG. 8 b , the plate bar  30  is shown in a top view according to this modified embodiment. The plate bar according to this embodiment can be made smaller than in the embodiment according to FIG. 2 a , since the draining connection  35  does not have to be arranged separately but is formed on the abutment  14 . 
     If the draining connection  35  is in fact used for emptying and not for filling the bag  15 , which is also possible in principle, the drain level in this embodiment is found at the level of the piercing device  13 , so that, under certain circumstances, no complete emptying is possible. However, the plate bar  30  having a piercing device  12 , abutment  14  and draining connection  35  can be substantially more simple. 
     In FIG. 8 c , a partial sectional view of the piercing device  13  is shown which is modified vis-à-vis the embodiment shown in FIG. 3 a . Different than with the operating piston  29  of the embodiment according to FIG. 3 a , a flow outlet  56  is made between the operating piston  29  and the punch  13 , so that, once the bag  15  has been pierced by means of punch  13 , substance can reach from the bag  15  into the interior of the operating piston  29  or in the operating piston  29  into bag  15 . In order to be able to connect a connection line  47 ,  48 ,  49  or a drain line  46 , an internal thread  60  is worked into the recess  54  of operating piston  29 . The recess  54  defines together with the internal thread  69  in this embodiment a connection  57  for the connection of supplementary bags  43 ,  44 ,  45  via connecting lines  47 ,  48 ,  49  or for connecting a drain line  46 . 
     For example, the supplementary bags  43 ,  44 ,  45  shown in FIG. 7 can be provided with a plate bar  30  and piercing device  12  according to FIGS. 8 a ,  8   b  and  8   c . The bag  15  having an outer jacket  11  and an inner jacket  27  is, on the other hand, equipped with a plate bar  30  as per FIGS. 2 a  and  2   b . The idea, to make the abutment  14  with a draining connection  35  and/or providing a flow outlet  56  in the operating piston  29  is claimed as essential to the invention independent from inserting a second substance. 
     The bag system shown in FIG. 7 is distinguished by a high-quality bag  15  that enables a visual control possibility when a transparent jacket  11  is provided and by supplementary bags  43 ,  44 ,  45 . The supplementary bags  43 ,  44 ,  45  enable numerous additional application possibilities (mixing, staggered in time, supply of substance completely spaced in time, etc.) and are, moreover, structured substantially more simply, both with respect to the bags  43 ,  44 ,  45  and the plate bar  30 . 
     
       
         
               
             
               
               
               
             
           
               
                   
               
               
                 List of Reference Numbers 
               
               
                   
               
             
             
               
                   
               
             
          
           
               
                   
                 10 
                 Receptacle 
               
               
                   
                 11 
                 Jacket (outer) 
               
               
                   
                 12 
                 Piercing device 
               
               
                   
                 13 
                 Punch (piercing device) 
               
               
                   
                 14 
                 Abutment 
               
               
                   
                 15 
                 Bag 
               
               
                   
                 16 
                 Separating film 
               
               
                   
                 17 
                 Cutting ribs 
               
               
                   
                 18 
                 Protective film (substance cartridge) 
               
               
                   
                 20 
                 Substance cartridge 
               
               
                   
                 21 
                 Opening 
               
               
                   
                 22 
                 Connection 
               
               
                   
                 23 
                 Protective film (abutment) 
               
               
                   
                 27 
                 Jacket 
               
               
                   
                 28 
                 Cylindrical guide 
               
               
                   
                 29 
                 Operating piston 
               
               
                   
                 30 
                 Plate bar 
               
               
                   
                 31 
                 Front plate 
               
               
                   
                 32 
                 Rear plate 
               
               
                   
                 33 
                 Guide ribs 
               
               
                   
                 34 
                 Groove 
               
               
                   
                 35 
                 Draining connection 
               
               
                   
                 36 
                 Connecting piece (inner) 
               
               
                   
                 37 
                 Connecting piece (outer) 
               
               
                   
                 38 
                 Internal thread 
               
               
                   
                 39 
                 Film hinge 
               
               
                   
                 40 
                 Intermediate piece 
               
               
                   
                 41a 
                 Punch (substance cartridge) 
               
               
                   
                 41b 
                 Punch (intermediate piece) 
               
               
                   
                 42 
                 Expansion 
               
               
                   
                 43, 44, 45 
                 Supplementary bags 
               
               
                   
                 46 
                 Drain line 
               
               
                   
                 47, 48, 49 
                 Connecting lines 
               
               
                   
                 50 
                 First substance 
               
               
                   
                 51 
                 Second substance 
               
               
                   
                 52, 53 
                 Film edges 
               
               
                   
                 54 
                 Recess 
               
               
                   
                 55 
                 Adapter 
               
               
                   
                 56 
                 Flow outlet 
               
               
                   
                 57 
                 Connection (operating piston) 
               
               
                   
                 58 
                 Hat-shaped cap 
               
               
                   
                 59 
                 Wall 
               
               
                   
                 60 
                 Internal thread 
               
               
                   
                 61 
                 Chamber