Abstract:
A method and system for detecting heart diseases, especially the coronary artery diseases, comprises the steps of obtaining twelve (12) lead cardiac electrical signals from a patient, mathematically transforming the time-domain wave signals into twelve (12) frequency-domain amplitude spectra with one for each of the 12 leads, selecting a number of amplitude readings in the low frequency range of 0 Hz to 25 Hz of the frequency amplitude spectrum density curves for analysis, from a reference clinical database of established diagnostic criterion values selecting diagnostic indexes by which the presence of heart disease is judged, determining the pathological values of diagnostic indexes for each lead, comparing the value of each diagnostic index against the value of said index in the database for detection of heart diseases, compiling and visually displaying all 12 amplitude spectrum density curves with their respective diagnostic indexes in one picture for diagnostic reading thereby accomplishing the detection of heart diseases, compiling and visually displaying the value of the diagnostic indexes indicative of coronary health for all 12 leads in one picture for diagnostic reading thereby accomplishing the detection of coronary artery diseases, further analyzing the cardiac electrical signals of lead II and lead V5 to determine a second set of diagnostic indexes, comparing against a reference clinical database of established diagnostic criterion for these indexes, compiling and displaying the results that are indicative of the patient&#39;s coronary health of the left ventricular, thereby accomplishing the detection of coronary artery diseases of the left ventricular.

Description:
FIELD OF INVENTION  
       [0001]     The present invention related to a method and system whereby the cardio electrical signals are collected by a plurality of detecting electrodes and transformed into frequency-domain spectra to obtain vital information which is then compiled and visually displayed for the detection of the heart diseases, especially the coronary artery diseases.  
       DESCRIPTION OF THE PRIOR ART  
       [0002]     Coronary artery diseases have been the leading cause of death in the United States and a major concern in the medical field over the years. With the invention of electrocardiogram (ECG) technology more than 100 years ago, physicians have been interpreting the changes in the ECG to detect various heart diseases, including the coronary artery diseases. The advantage of interpreting ECG is this technique is non-invasive, but the major drawback is that it provides less than 50% in accuracy with even less in specificity. In the last twenty years, with the advance in microprocessor, ECG interpretation has been computerized to eliminate the human error, however since the changes in ECG are generally very minor and in some case none, the improvement in accuracy and specificity has been rather limited. There are many other technologies available to the doctors for the detection of heart diseases, such as the nuclear scanning which is non-invasive but expensive to run, catheterization or coronary angiography which is a invasive and expensive procedure. These testing procedures have often been used as a last test to confirm the existence of heart diseases after positive finding in the preliminary testing.  
         [0003]     From the technical point of view, an ECG (electrocardiogram) is a compilation and recording of cardiac electrical signal in time sequence. Since ECG composes a number of different electrical currents, it is a complex time-domain signal. When an area of heart muscle is damaged due to lack of blood supply, the characteristic of electrical currents traveling through the heart muscle is affected with change in amplitude and/or direction. Those changes in some cases will show up in an ECG and can be interpreted to diagnose the existence of heart diseases. However, some of these changes are so very minor and cannot be interpreted by a well trained professional. Therefore, ECG still remains as a preliminary screening tool for the doctors because it gives less than satisfactory results in the accuracy and specificity.  
         [0004]     In 1965, Fast Fourier Transformation (FFT), a very efficient algorithm, was developed to implement the Discrete Fourier Transformation which was the most straightforward mathematical procedure to transform a time-domain signal into its frequency components. With the invention and advance of computer technology, the fast Fourier transformation of a complex ECG time-domain signal into its unique frequency components can be accomplished in a second. With the FFT, a tremendous amount of research work has been done in the recent years in the analysis of the frequency-domain components of a non-invasive ECG for the detection of heart disease. For instance, Chamoun&#39;s patent (U.S. Pat. No. 5,020,540) described a method and system of choosing and extracting an arrhythmia-free QRST complex from a time-domain ECG as a template and analyzing its frequency components in a very high frequency range (150-250 Hz) to detect various types of heart diseases. The shortcoming in this approach are two folds, one is Chamoun&#39;s per-determination to use only an arrhythmia-free QRST complex for frequency analysis which artificially excludes a group of patients from testing. The second one is Chamoun&#39;s only uses the high frequency components in the range of 150 to 250 Hz for the analysis when a major portion of the cardiac electrical frequency components after FFT transformation are in the 0 to 50 Hz frequency range. Chamoun&#39;s overlook of the low frequency components from 0 Hz to 25 Hz of an ECG complex leaves a big gap in the research spectrum. The present invention without predetermination of which segment of ECG signal should be use looks at the entire cardiac electrical signals in their low frequency range of 0 to 25 Hz which a treasury of useful information is located.  
         [0005]     At the time of Chomoun&#39;s patent, Shen&#39;s patent (U.S. Pat. No. 5,029,082) revealed an apparatus for detecting and processing electrocardiogram (ECG) signals for two selected leads in their frequency domain. Later, Feng in his two patents (U.S. Pat. Nos. 5,509,425 and 5,649,544) carried out more research work using the same ECG signal from two selected leads, Lead II and Lead V5, as in Shen&#39;s patent for frequency analysis. Both Feng&#39;s patents describe a method to mathematically determine a plurality of functions and a set of indices for each function for diagnosing a cardiac condition and warning of heart attack of a patient. However, there are many shortcomings in Feng&#39;s approach. Feng&#39;s patent uses ECG signal collected form two selected leads, II and V5, for frequency analysis and fails to give due consideration of the useful information from other cardiac electrical signals collected by other ten ECG leads and thus unnecessarily forfeited the benefit from their analysis. The other concern in Feng&#39;s patents is neither of Feng&#39;s two patents has ever established any relationship between the six functions and 73 indices identified in the patents, and how these indices can be used for the detection of heart diseases. Presumably each of those indices is to be used to detect heart disease, but Feng&#39;s patents do no provide any explanation or direction on how to use those indices.  
         [0006]     After Feng&#39;s patents, frequency analysis of ECG signals from all 12 leads was described later in Fang&#39;s patents (U.S. Pat. Nos. 6,148,228 and 6,638,232) entitled system and method for detecting and locating heart diseases. A base value is obtained by multiplying a patient&#39;s heart beats per second by a scaling quantity of 5, and then comparing the area of a power spectrum from 0 Hz to the base value over the area from said base value to infinite to get an area ratio, and then using the area ratio to establish an evaluation standard indicative of coronary artery diseases. Although Fang&#39;s patents did not mention that the technology involved is of low frequency analysis, the area calculated in Fang&#39;s patents is from 0 Hz to the base value of 5 Hz and fro the base value of 5 Hz to infinite in frequency. They nevertheless cover the low frequency range of 0 Hz to 25 Hz. Fang&#39;s patents also use the cardiac electrical signals of all 12 leads for his frequency analysis. The shortcomings in Fang&#39;s patents are that first the scope of the work is limited to the use of a base value and area ratio to locate the coronary artery diseases and secondly the failure to use the information from the frequency components of all 12 leads to achieve a more systematic and efficient approach to detect the heart diseases.  
         [0007]     The present invention provides a method and system for a visual systematic approach in the detection of the heart diseases. Seeing is a thousand words. This invention is the first to provide a visual reading of spectrum supported by diagnostic indexes. It examines the frequency components in the low frequency range from 0 Hz to 25 Hz for cardiac electrical signals from all 12 leads, determines their respective diagnostic indexes, compiles all the information in three unique visual displays. The first visual display shows 12 frequency spectra, one for each lead, with their respective indexes for diagnosis of arrhythmia, hypertrophy, myocardium injuries and coronary artery diseases from ischemia to myocardial infarction. The second visual display shows the value of the diagnostic indexes indicative of coronary health for all 12 leads in one picture for diagnostic reading thereby accomplishing the detection of coronary artery diseases. The third and final visual display is to check the health of the left ventricular for any serious diseases that may cause heart attack.  
       SUMMARY OF THE INVENTION  
       [0008]     An object of the present invention is to provide a method and system of low frequency analysis of the cardiac electrical signals of all 12 leads for the detection of heart diseases, especially the coronary artery diseases.  
         [0009]     Another object of the present invention is to provide a method and system of compiling and displaying the diagnostic information of all 12 lead for visual reading and detecting the presence of heart diseases.  
         [0010]     Another object of the present invention is to provide a method and system of compiling and displaying the diagnostic information for coronary health of the heart for visual reading and detecting the presence and location of coronary artery disease.  
         [0011]     Yet another object of the present invention is to provide a method and system of compiling and displaying the diagnostic information of low frequency analysis of two leads, II and V5, for visual reading and detecting patient&#39;s coronary health of the left ventricular, thereby accomplishing the detection of coronary artery diseases in the left ventricular, especially the presence of myocardium infarction, a serious form of coronary artery diseases. 
     
    
     BRIEF DESCRIPTION OF THE DRAWINGS  
       [0012]      FIG. 1  is a schematic diagram of the apparatus components of the system used in the present invention;  
         [0013]      FIG. 2  is an overview flow chart of the operation of the system used in the present invention;  
         [0014]      FIG. 3 , is a picture of a frequency amplitude spectrum density curve along with the diagnostic indexes generated by the method and system of the present invention for one of the 12 leads  
         [0015]      FIG. 4  is the graphical representation of one of the diagnostic outputs provided by the method and process of the present invention showing the visual display of 12 individual frequency amplitude spectrum density curves with one for each lead plus respective diagnostic indexes generated in connection with the established clinical diagnostic criterions;  
         [0016]      FIG. 5  is the graphical representation of one of the diagnostic outputs provided by the method and system of the present invention showing the visual display of 12 individual coronary artery disease detection columns with the diagnostic line generated in connection with the established clinical diagnostic criterions.  
         [0017]      FIG. 6  is the graphical representation of one of the diagnostic outputs provided by the method and system of the present invention showing the visual display of 2 individual frequency amplitude spectrum density curves, one for lead II and the other for lead V5, and the graphs for signal analysis for these two leads plus the diagnostic indexes generated in connection with the established clinical diagnostic criterions. 
     
    
     DESCRIPTION OF THE PREFERRED EMBODIMENTS  
       [0018]     Referring to  FIG. 1 , the apparatus used in the present invention consists of a conventional 12 lead electrocardiograph (ECG) patient cable  10  having a set of ten surface electrodes (collectively  101 ) attached to the surface of a test subject  1  at the prescribed positions, and the other end  102  of the 12 lead ECG patient cable  10  connected to a computer  12 . This computer  12  consists of a data collector  122  and a CPU unit  124 . The data collector  122  has a serial port to connect the 12 lead ECG patient cable  10 , a A/D converter, a amplifier, filters, and an electrical isolator. The CPU  124  is a micro processor to process the input information. The computer  12  is connected to a monitor  16  and a printer  18 . The monitor  18  is for visual display and the printer  16  is to print out the output information on commend by the computer  12  operated by a keyboard  14  and a mouse  15  connected to the computer  12  for the operation.  
         [0019]     The cardiac electrical signals  20  are collected by the electrodes  101  of a 12 lead ECG patient cable  10 , transmitted to a data collector  122 . After the signals  20  have been digitized by an A/D converter, amplified by an amplifier, filtered off the noise by a filters, and transmitted through the electrical isolator to a CPU  124 . The CPU  124  has been pre-installed with a proprietary software and a proprietary database of clinical studies to perform the data analysis. Once the cardiac electrical signals  20  are transmitted into the CPU  124 , the CPU  124  will analyze the information and present the information commended by a operator using a keyboard  14  and mouse  15 .  
         [0020]     Referring to  FIG. 2 , an overview of the flow chart showing the operation of the system of the present invention. The cardiac electrical signals  20  collected by each of a 12 lead ECG patient cable  10  of a tested subject  1  are first mathematically transformed from time-domain into their respective frequency data  202  by means of Fast Fourier Transformation equations. These frequency data  202  are plotted into 12 separate and individual frequency amplitude spectrum density curves  204 . From each of the frequency amplitude spectrum density curves, a number of frequency peaks are selected and their pathological value calculated and labeled with an alphabetic letter as the diagnostic indexes  206 . Comparing the pathological values of these diagnostic indexes against the pathological values that have been established clinically and store in the database to determine a positive (“+”) sign or a negative (“−”) sign for those diagnostic indexes  208 . Once the sign for each diagnostic index has been identified, each of the 12 frequency amplitude spectrum density curves together with diagnostic indexes plus each of the sign are compiled together and displayed  210  either with a monitor and printed out by a printer. If there are more than one positive (“+”) index shown for any one of the 12 the frequency amplitude spectrum density curves  41 - 52 , the next recommended step is to obtain the second display to find out whether there is coronary artery diseases  212 .  
         [0021]     From diagnostic indexes  208 , one index is selected. Takes out the already calculated pathological value for said index for each of the 12 leads and plots against said respective lead to development a graphical display of a plurality of multi-colors diagnostic columns for the detection and location of coronary artery diseases  212 .  
         [0022]     The third step is to analyze the frequency components of the cardiac electrical signals from lead II and lead V5  214 . The reason of selecting these two leads is because the cardiac electrical signals detected by these two lead travel through the frontal left ventricular area of a heart where coronary diseases would cause more serious consequences than that of other part of the heart. Adopting the two fundamental methods used in the digital signal processing to study the transmission function of a device, transfer function in phase angle shift and impulse response, to analyze the frequency components in the frequency range form 0 Hz to 25 Hz of the cardiac electrical signals from these two leads  216 . Using the cardiac electrical signal of lead V5 as the input signal and lead II as the output signal. Pathological values for the phase angle shift of the transfer function of these two leads are calculated, compared against said value in the clinically established database to determine a diagnostic index has a positive (“+”) sign or a negative (“−”) sign  218 . The degree in phase angle shift is plotted against the frequency from 0 Hz to 25 Hz to get a phase shift curve. Compile the diagnostic index and phase shift curve in one picture  224  which can be displayed on a monitor  16  or printed out by a printer  18  for visual diagnosis.  
         [0023]     The degree in phase angle shift is used to measured the conductivity function of a heart, particularly the frontal area of the left ventricular. Further diagnosis for the nature and scope of coronary artery disease analysis of left ventricular is carried out with the use of mathematical approach of impulse response in the digital signal processing  214 . In the present invention, pathological values for the impulse response between these two leads are calculated, and diagnostic indexes are selected and labeled by alphabetic letters. A positive (“+”) sign or a negative (“−”) sign is determined for each of the diagnostic indexes comparing against said values in the clinically established database  222 . The impulse response co-efficiency verses time in milli-second is plotted to give an impulse response curve. Putting together the frequency amplitude spectrum density curves for lead II and lead V5, phase angle shift curve, impulse response curve and their respective diagnostic indexes, a two lead visual diagnostic analysis is compiled in one picture  224  which can be displayed on a monitor  16  or printed out by a printer  18 .  
         [0024]     It is recommended that a diagnostic procedure starts with the visual analysis of 12 lead frequency amplitude spectrum density curves  210 . If the diagnostic indexes indicate possible presence of coronary artery diseases, the next step is to go to the visual display of multiple diagnostic columns  212  to find out which area of heart has coronary artery disease. Once the existence of the coronary artery disease is confirmed, then go to the two lead visual diagnostic analysis  224  to detect any heart diseases in the left ventricular.  
         [0025]     Referring  FIG. 3 , a picture of a frequency amplitude spectrum density curve along  30  with the diagnostic indexes generated by the method and system of the present invention for one of the 12 leads. The frequency amplitude spectrum density curve  30  is a result of plotting the value of frequency (Hz) as the horizontal (X) axis  302  and the value of amplitude (uV) as the vertical (Y) axis  304 . H  306 ( a ), U  308 ( a ), N  310 ( a ), B  312 ( a ), A  314 ( a ), F  316 ( a ) are the diagnostic indexes in alphabetic letters, and  309 ( b ),  308 ( b ),  310 ( b ),  312 ( b ),  314 ( b ),  316 ( b ) are sign of positive (“+”) or negative (“−”) for each of the six diagnostic indexes after compared against the established diagnostic criterions in the database.  
         [0026]     The letter index H  306 ( a ) is a diagnostic index established by analyzing a database of clinical diagnostic criterions for detection of insufficient myocardial power in the myocardium caused by lack of blood supply. The pathological value for index H  306 ( a ) is calculated by comparing the amplitude value of the first and second peak in the spectrum density curve. If the amplitude ratio of the second peak over the first peaks is more than 0.75, the letter H  306 ( a ) index has a sign  306 ( b ) of positive (“+”) which indicates that the area of heart where the lead points to does not have sufficient myocardial power due to insufficient blood supply to that area. This is the beginning stage of developing coronary artery diseases.  
         [0027]     The letter index U  308 ( a ) is a diagnostic index established by analyzing a database of clinical diagnostic criterions for detection of arrhythmia. The pathological value for index U  308 ( a ) is calculated by measuring the distance between one frequency peak and its adjacent frequency peak in a frequency amplitude spectrum density curve and comparing all the peak-peak distance for the entire frequency range from 0 Hz to 25 Hz. If there is a discrepance in the distance among the adjacent two peaks which means some distance is larger or smaller than the others, the letter index U  308 ( a ) has a sign  308 ( b ) of positive (“+”) which indicates that the tested subject has arrhythmia.  
         [0028]     The letter index N  310 ( a ) is a diagnostic index established by analyzing database of clinical diagnostic criterions for detection of injuries in myocardium. The pathological value of index N  310 ( a ) is calculated by measuring the amplitude value of the first peak in a frequency amplitude spectrum density curve. If at the frequency point where the first peak should be shows no amplitude value or less than 3 uV in amplitude, the letter index N  310 ( a ) has a sign  310 ( b ) of positive (“+”) which indicates the presence of myocardial injuries.  
         [0029]     The letter index B  312 ( a ) is another diagnostic index established by analyzing the database of clinical diagnostic criterions for detection of hypertrophy. The pathological value of index B  312 ( a ) is calculated by measuring the amplitude value of the first and second peaks in the frequency amplitude spectrum density curve. When the mathematical sum in uV from the first peak and second peak is over 80 uV, the index B  312 ( a ) has a sign  312 ( b ) of positive (“+”) which indicates the presence of hypertrophy.  
         [0030]     The letter index A  314 ( a ) is another diagnostic index found to have diagnostic significance based on the database of clinical diagnostic criterions for detection of early stage of ischemia. The pathological value is calculated by comparing the amplitude values of the second peak against the amplitude value of the first peak. If one of the pathological value is over 1.00, the index A  314 ( a ) has a sign  314 ( b ) of positive (“+”) which indicates the presence of ischemia.  
         [0031]     The letter index F  316 ( a ) is another diagnostic index that has been clinically established for the detection of use of myocardial compensation which generally takes one or two years to develop after having ischemia. The pathological value is calculated by comparing the amplitude values of any one peak from the fifth peak to the thirtieth peak against the amplitude value of the first peak. If one of the pathological value is over 0.75, the index F  316 ( a ) has a sign  316 ( b ) positive (“+”) which indicates the heart has used myocardial compensation to carry its pumping function as a consequence of prolong and advanced ischemia, or myocardial infarction.  
         [0032]     Referring to  FIG. 4 , a graphical representation  40  of the first of three diagnostic outputs provided by the method and process of the present invention showing a visual display of 12 individual frequency amplitude spectrum density curves with one for each of the 12 leads along with their respective diagnostic indexes generated after comparing against the established clinical diagnostic criterions. There are 12 frequency amplitude spectrum density curves  41 - 52 , one for each of the 12 leads. Starting from the one on the left hand upper corner  41 , there is an alphabetic letter I  412  specifying that this spectrum density curve  414  is the spectrum density curve for lead I, the six alphabetic letters to the right of the letter I  412  are the same six diagnostic indexes as identified and explained in  FIG. 3 . They are H  416 ( a ), U  416 ( b ), N  416 {circle around (C)}), B  416 ( d ), A  416 ( e ) and F  426 ( f ) with their respective positive (“+”) sign or negative (“−”) sign  418 ( a )-( f ) directly under said each of the alphabetic letters.  
         [0033]     This graphical representation  40  shows 12 separate and individual spectrum density curves places in three rows with four in one row. The first and top row  40 ( a ) shows the spectrum density curves for lead I  41 , lead aVR  44 , lead V1  47  and lead V4  50 . The second and middle row  40 ( b ) has also four spectrum density curves for lead II  42 , lead aVL  45 , lead V2  49  and lead V5  51 . The last and bottom row shows four spectrum density curves for lead III  43 , lead aVF  46 , lead V3  49  and lead V6  52 . Each curve also has the diagnostic indexes in alphabetic letters (a)-(f) and their respective positive (“+”) or negative (“−”) signs (a)-(f).  
         [0034]     Referring to  FIG. 5 , a graphical representation  55  of the second of three diagnostic outputs provided by the method and system of the present invention showing the visual display of fourteen individual coronary artery disease detection columns with a diagnostic line generated by the method and system of the present invention in connection with the established clinical diagnostic criterions. The displaying representation  55  is a plot of pathological value in uV and identification of each lead. The pathological value in uV is for the vertical (Y) axis  554  and the identification of each lead is the horizontal (X) axis  552 . Using the pathological value of a selected diagnostic index for each of the 12 leads and plot against their respective individual lead in two lead groups in the order of I  556 , aVR  558 , II  560 , aVF  562 , III  564 , aVL  566 , I  568  for the limb group, and V1  570 , V2  572 , V3  574 , V4  576 , V5  578 , V6  580 , V1  582  for the chest group, to develop a graph with a total of 14 multi-colors diagnostic columns  556 - 582 . There is a horizontal line called “diagnostic line”  590  starting at a point of Y axis  554  where the pathological value for which the positive (“+”) and negative (“−”) index is determined, and traveling parallel all the way to the end of the X axis  552 . When a diagnostic column for one lead passes over the diagnostic line  590 , it indicates an abnormal condition at the area where said lead points to. The color of each column is blue at the base line  552  and changes gradually to green and then yellow as the pathological value for said lead increases and the column moves upward until it reaches the diagnostic line  590 . Once the column goes over the diagnostic line  590 , the color changes from orange and then red as the pathological value increases more. To detect the general location of coronary artery diseases, we observe how many columns go over the diagnostic line  590 . When there are three consecutive columns in one group, limb group and/or chest group, going over the diagnostic line  590  with top layer of the color being orange or red, it indicates the presence of coronary artery disease at the area where the lead having the tallest column points to.  
         [0035]     Referring  FIG. 6 , a graphical representation of the last of three diagnostic outputs provided by the method and system of the present invention showing the visual display of two individual frequency amplitude spectrum density curves, one for lead II and the other for lead V5, and two figures, phase shift and impulse response, of signal analysis of same two leads plus diagnostic indexes generated after comparing with the established clinical diagnostic criterions.  
         [0036]     This display representation consists of four graphs, two in the first and top row and two in the second and bottom row. The two graphs in the top row are the frequency amplitude spectrum density curves together with six diagnostic indexes and their respective positive or negative sign for lead II  42  and lead V5  51 . The two graphs in the bottom row are the phase shift curve  62  for the transfer function in phase angle shift and impulse response curve  64  for the same two leads.  
         [0037]     Phase shift is the angle shift between the input current and output current. In method and system of the present invention, the cardiac electrical current of lead V5 is used as the input current and the cardiac electrical current of lead II as the output current. Applying the mathematic equations for the transfer function in phase angle shift in digital signal processing to calculate the degree of phase shift between these two signals at every 0.0025 Hz frequency increment for the entire frequency range from 0 Hz to 25 Hz.  
         [0038]     For the present invention, a phase shift curve  62  is a plot of degree of phase shift angle  622  from −180 degree to +180 degree as the vertical (Y) axis, and the frequency  624  from 0 Hz to 25 Hz as the horizontal (X) axis. The angle in phase shift at every frequency from 0 to 25 Hz is calculated and plotted to give a phase shift curve  626 . There is a rectangular area  628  outlined from the phase shift angle of −90 degree to +90 degree of the Y axis  630  and 6 Hz to 20 Hz of the X axis  632  where diagnosis is carried out. The pathological value is calculated by measuring every phase shift angle against the absolute 90 degree from 6 to 20 Hz. If the calculated value is larger than 1.00, then the diagnostic index P  634  had a sign  636  of positive (“+”) which indicates abnormality in the myocardial conduction function. In addition, this diagnosis can be accomplished by observing how the phase shift curve travels within this diagnostic rectangular area  628 . When the phase shift curve  626  at any frequency point between 6 Hz to 20 Hz  632  travels out side of the rectangular area  628 , it indicates abnormality in myocardial conduction function.  
         [0039]     In digital signal processing, when a system is stimulated with an electrical impulse, the output response can also be mathematically calculated by the inversed Fourier transformation of the transfer function in amplitude. In the method and system of the present invention, the cardiac electrical current of lead V5 is treated as the stimulating input current and the cardiac electrical current of lead II is treated as the excited output current. The relative impulse response of cardiac electrical current of lead V5 when stimulated by the cardiac electrical current of lead II is mathematically calculated for every frequency point in 0.0025 Hz frequency increment from 0 Hz to 25 Hz frequency range. The value for impulse response relativity  642  as the vertical (Y) axis is plotted against certain time intervals  644  from time −M to 0 to +M where M is a non-zero integral value in milli-second to get a impulse response cure curve  646 .  
         [0040]     Based on the clinically established criterions for a healthy heart, for a impulse response graph  64 , there is only one narrow and sharp peak standing above the base line of the impulse response curve  646  at zero (0) point  648  and this peak is identified as the main peak  650 . The pathological value is calculated by detecting the existence of any peak other than the main peak  650  above or below the impulse response base line from time −M to +M. Four diagnostic indexes were developed from the database D  650 ( a ), M  652 ( a ), R  654 ( a ), and C  656 ( a ) and their respective sign of  650 ( b )- 656 ( b ) of positive (“+”) or negative (“−”). When the main peak  650  is at an inversed position from the X axis at zero (0) point  648 , the diagnostic index D  650 ( a ) has a positive (“+”) sign  650 ( b ) which indicates coronary artery diseases in the left ventricular. When there are multiple peaks in place of the main peak  650 , the diagnostic index M  652 ( a ) has a sign  652 ( b ) of positive (“+”) which indicates poor conduction function in the left ventricular. When there is one peak on each side with a distance from the main peak  650 , the diagnostic index R  654 ( a ) has a sign  654 ( b ) of positive (“+”) which indicates advanced ischemia with possible myocardial infarction in the left ventricular. When there is multiple peaks on either side of the main peak  650 , but not replacing the main peak  650 , the diagnostic index C  656 ( a ) has a sign  656 ( b ) of positive (“+”) which indicates latent arrhythmia.  
         [0041]     In the method and system of the present invention, diagnosis of the left ventricular can be further accomplished by visually observing the impulse response curve along with these four indexes  650 ( a )- 656 ( a ) and their respective sign  650 ( b )- 656 ( b ) of positive (“+”) or negative (“−”) for each index for coronary artery diseases, poor conduction function, ischemia with possible myocardial infarction and latent arrhythmia.