Abstract:
The present disclosure relates to a portable ampoule with a specialized tip and sealer. In a general aspect, the portable ampoule for dispensing fluid may include a body configured to contain cleansing solution. A neck may be coupled to the body and configured to control the flow of the solution. A tip may be coupled to the neck and have an aperture for solution release. A sealing device may be coupled to the tip and configured to seal the aperture. The sealing device may permanently unseal the aperture upon decoupling from the tip.

Description:
TECHNICAL FIELD 
       [0001]    The subject matter of this application is generally related to dispensers. 
       BACKGROUND 
       [0002]    People in many parts of the world perform nasal cleansing (or nasal irrigation) using a neti pots or other products on a routine basis. Nasal cleansing is also incorporated into some forms of yoga practice, such as in Jala neti. Jala neti is a Sanskrit term that refers to cleansing and means “water cleansing”. The solution for rinsing the nasal passages can be a saline solution. Some patients use nasal rinsing to reduce allergies, improve breathing, eliminate post-nasal drip or sinus infections, moisten dry nasal passages, avoid catching a cold, or otherwise generally improve one&#39;s health. Other uses are possible. Conventional nasal rinse products, however, are bulky and do not fit within purses, backpacks, briefcases, or other personal items that are carried around. 
       SUMMARY 
       [0003]    The present disclosure relates to a portable ampoule with a specialized tip and sealer. In a general aspect, the portable ampoule for dispensing fluid may include a body configured to contain cleansing solution. A neck may be coupled to the body and configured to control the flow of the solution. A tip may be coupled to the neck and have an aperture for solution release. A sealing device may be coupled to the tip and configured to seal the aperture. The sealing device may permanently unseal the aperture upon decoupling from the tip. 
         [0004]    Implementations may include one or more of the following features. The sealing device may be for a single use such that upon removing the sealing device from the tip, the sealing device is permanently displaced from the tip. The sealing device may include an opener having a twist coupler to facilitate twisting motion for removing the sealing device to unseal the aperture. The opener may be a planar holding structure to accommodate application of moment or torque to the twist coupler. The opener may include an outer rim to provide torque support and an inner rim to secure the twist coupler to the outer rim. The sealing device may include a sealer and the twist coupler may be coupled to the tip through the sealer. 
         [0005]    The body may include a rib structure to facilitate holding or gripping of the body to avoid slipping motion generated when the body is rotated in an opposite direction with respect to the sealing device. The rib structure may be flush or contiguous with edges of the opener. The rib structure may extend from a bottom portion of the tip to a bottom portion of the body, wherein a bottom surface of the opener body aligns with the bottom portion of the tip. The twist coupler includes inner side walls that conform with but do not contact sidewalls of the tip. 
         [0006]    The tip may be further configured to attenuate the pressure of solution stored in the body and facilitate dispensing of the solution with sufficient pressure to deliver the solution to nasal tissue without displacing the nasal tissue. The neck may have a diameter smaller than a diameter of the body to facilitate a dispensing speed of the solution. The tip may be conically shaped with a convex curved surface tapered from a surface on which the aperture is formed to a bottom portion of the tip. The bottom portion may include a diameter with sufficient dimension to prevent the tip from extending into a user&#39;s nostril. The bottom portion of the tip may include rounded or chamfered edges. The tip may include a tapered surface that conforms to nostrils of different sizes. 
         [0007]    The details of one or more implementations of the subject matter described in this specification are set forth in the accompanying drawings and the description below. Other features, aspects, and advantages of the subject matter will become apparent from the description, the drawings, and the claims 
     
    
     
       BRIEF DESCRIPTION OF DRAWINGS 
         [0008]      FIG. 1A  is a schematic front view of an ampoule. 
           [0009]      FIG. 1B  is a schematic top view of the ampoule. 
           [0010]      FIG. 2  is a schematic side view of the ampoule. 
           [0011]      FIG. 3  is a schematic cross-sectional view at A-A of the ampoule. 
           [0012]      FIGS. 4A and 4B  are schematic views of the ampoule before and after opening respectively. 
           [0013]      FIG. 5A  is a schematic view of a second ampoule implementation. 
           [0014]      FIG. 5B  is a schematic cross-sectional view along the longitudinal axis of the second ampoule implementation. 
       
    
    
       [0015]    Like reference symbols in the various drawings indicate like elements. 
       DETAILED DESCRIPTION 
       [0016]      FIG. 1A  is a schematic front view of an ampoule  100 . As shown in  FIG. 1A , the ampoule  100  includes a body  101 , a neck  102 , a tip  103  and an opener  104 . The neck  102  connects the body  101  to the tip  103 . The opener  104  allows users to twist open the tip  103  at a twist coupler  105 . The body  101  can be, for example, a container of saline solution or any other fluid suitable for irrigating cavities (e.g. nasal cavities). The ampoule  100  can be used, for example, to provide nasal rinsing (or irrigation or nasal lavage), such as to treat allergies, improve breathing, eliminate post-nasal drip or sinus infections, moisten dry nasal passages, etc. In some implementations, the tip  103  can attenuate the pressure of fluid stored in the body  101 , dispensing fluid at a gentle pressure. The gentle pressure can be sufficient to deliver a flow of fluid to tissue without the pressure being so great as to displace the tissue. 
         [0017]    In some implementations, the body  101  can be a fluid container (e.g. a bottle, can or other container) that securely stores fluid and allows users to apply pressure (e.g. to the container) to expel the stored fluid. For example, the body  101  can be made of thermoplastic polymers, thermosetting polymers, or any other appropriate materials that allows for deformation in order to pressurize the bottle for fluid release. In some implementations, the ampoule  100  can be pressurized for maintaining shape during transportation. In some implementations, the body  101  is a cylindrical shape of a uniform diameter. In some implementations, the diameter can vary along its longitudinal axis, for example, a tapered shape, a curved shape, a diamond shape, or other shapes. The body  101  can be a thin-walled structure of uniform thickness and/or variable thickness for functional requirements. For example, to facilitate deformation, some locations on the body  101  can be thinner than the rest. As another example, other locations on the body  101  can be thicker for structural reinforcement, such as a portion at or near the bottom of the ampoule  100 . Grooves or depressions can be included in the body to facilitate gripping by the human hand. 
         [0018]    In some implementations, the dimension of the neck  102  can be tailored to accommodate an increase output flow velocity of fluid from the body  101 . The neck  102  can be made of the same material as the body  101 , such as thermoplastic polymers, thermosetting polymers, etc. In some implementations, the neck  102  is a cylindrical shape of a uniform diameter that is significantly smaller than that of the body  101  (e.g., the diameter of neck  102  is 50% smaller than the maximum diameter of the body  101 ). Other ratios between the diameter of the neck  102  and that of the body  101  are also contemplated. In some implementations, a small neck diameter allows the output flow velocity to increase (e.g., because for a given amount of fluid volume that is displaced, the narrower the cross-sectional area of a passage, the higher the flow velocity). The neck  102  can also be a thin-walled structure of uniform thickness and/or variable thickness for functional requirements. For example, at the location where the body  101  and the tip  103  intersects, extra wall thickness can be implemented to enhance structural integrity. 
         [0019]    As shown in  FIG. 1 , the tip  103  is connected to the neck  102 , which is partially encapsulated by the twist coupler  105 . An aperture  109  is revealed upon removing the twist coupler  105 . In some implementations, the tip  103  can be conically shaped with a convex curved surface leading from the aperture  109  toward the bottom portion  111  of the tip  103 . In some implementations, the tip  103  can be gumdrop- or mushroom-shaped. The tip  103  may include rounded edges such as an upper rounded edge and a lower rounded edge. The rounded edges may have a substantially large rounding radius to facilitate manufacturing process and avoid causing discomfort to user during use and/or handling. For example, the upper rounded edge can be of a rounding radius between 0.5 to 4 mm, such as 1 mm. This allows the tip  103  to comfortably contact with the user at various insertion angles without excessive friction to cause irritation or discomfort. The lower rounded edge may have a rounding radius between 1 to 6 mm, such as 2 mm. This allows the tip  103  to be safely completely enclosed by a user&#39;s nostril and cause minimum friction and discomfort during removal. This also allows the tip  103  to avoid stress concentration during production, transportation and use. 
         [0020]    The tip  103  can include a tapered surface that permits the tip  103  to conform to nostrils of different sizes. Specifically, the exterior of the tip  103  can be tapered outwardly. For example, the tip  103  tapers from a wide portion up (e.g., the portion near the bottom of the tip  103 ) to a narrow portion (e.g., the portion near the top of the tip  103 ). The tip  103  can be sized to prevent the wide portion from extending all the way into a user&#39;s nostril. In some implementations, the transition from the end of the wide portion to the neck  102  can be rounded or chamfered to avoid any sharp edges. The tip  103  can be made of the same material as the body  101 , such as thermoplastic polymers, thermosetting polymers, or other suitable materials tailored for human use. The tip  103  can be a thin-walled structure of approximate uniform thickness. 
         [0021]    In some implementations, the twist coupler  105  is breakably coupled to the tip  103  at the aperture  109  and reinforceably affixed to the opener  104 . The opener  104  can be sized to facilitate the twisting motion for twist opening the twist coupler  105 . In some implementations, the twist coupler  105  acts as a one-time seal to the tip  103  so that upon twist opening the twist coupler  105 , the twist coupler  105  is permanently displaced from the tip  103 . In so doing, the tip  103  cannot re-seal the aperture  109 , and the ampoule  100  can be discarded after one-time use. 
         [0022]    In some implementations, the twist coupler  105  is a thin-walled structure coupled to the tip  103  by, for example, heated compression or any similar techniques, sealingly adhering two adjacent walls that can be broken with a twisting motion when the shear stress exceeds the bonding strength between the two thin walls. The twist coupler  105  can be of a donut shape, a tire shape, or any other appropriate shape to encapsulate the aperture  109 . The twist coupler  105  can be made of the same material as the tip  103 , such as thermoplastic polymers, thermosetting polymers, and other suitable materials. 
         [0023]    In some implementations, the opener  104  is integrally and reinforceably affixed to the twist coupler  105 . The opener  104  serves as a holding structure for user&#39;s fingers to apply a moment/torque to the twist coupler  105 . In some implementations, the opener  104  is a plane structure of a thickness that defies significant bending deformation under normal use. The opener  104  may include an outer rim to provide torque support and an inner rim to secure the twist coupler to the outer rim. For example, the outer rim may be of a thicker thickness than the inner rim so that when a torque is applied to the outer rim, structural deformation is limited by the material strength of the outer rim. The thickness of the outer rim may be between about 1 and 4 mm, such as 2.5 mm. The primary function of the inner rim is to secure the twist coupler  105  to the outer rim. As the inner rim deforms under loading, tensile stress can become the major stress within the component to provide a transmitting force to rotate the twist coupler  105 . Therefore, the thickness of the inner rim may not require a large thickness, between about 0.5 to 2 mm, such as 1 mm. This also saves production material and reduces portable weight of the ampoule  100 . 
         [0024]    In some implementations, the opener  104  is affixed to a cap (not shown) instead of the twist coupler  105  for re-usable purposes. The cap may be a screw type cap that has spiral rails to fasten with the ampoule  100 . The aperture  109  may have an intruding structure coupling with the cap. The material for the cap may be flexible to allow deformation to occur to form a liquid-tight fit. This alternation allows user to protect the ampoule  100  before use (e.g., during transportation). 
         [0025]    In some implementations, a rib structure  107  is included along the longitudinal axis of the body  101  and in the plane defined by the opener  104 . The rib structure  107  allows users to conveniently hold and grip the body  101  and avoid a slipping motion in the rotational direction. For example, a user can use three fingers (e.g. a middle finger, a ring finger and a pinky) to grip around the cylindrical portion of the body  101  and the other two figures (e.g. a thumb and an index finger) to hold the planar portion of the rib structure  107 . This finger hold securely restricts motion of the tip  103  (e.g., to restrict the neck  102  and the body  101  from compliant motions such as rotation along with the opener  104 ). The user can then use the other hand&#39;s two fingers (e.g. a thumb and an index finger) to hold the opener  104  by the planar surface (e.g. pressing onto the surface, or to act on the rib portion), and apply a torque/moment to twist the opener  104  against the tip  103 . Excessive deformation occurs when the torque exceeds a predetermined value so that the deformation can cause the twist coupler  105  to break away from the tip  103 , revealing the aperture  109 . Therefore, the body  101  includes an outer rim (i.e. the planar portion of the rib structure  107  and the opener  104 ) to provide torque support and an inner rim (i.e. the material between the tip  103  and the opener  104 ) to secure the twist coupler  105  to the outer rim. 
         [0026]    As shown in  FIG. 1 , the opener  104  and the rib structure  1007  are separated below the bottom of the tip  103 . This allows the tip  103  be completely inserted into a user&#39;s nostril without obstruction and/or causing discomfort. The rib structure  107  may be confined to a contour that avoids contact with a user&#39;s nostril when the tip  103  is fully inserted. Although the opener  104  and the rib structure  107  are shown separated near the bottom of the tip  103 , other implementations also are contemplated in which the separation gap is placed at different locations, such as the shoulder of the body  101  or anywhere between the shoulder of the body  101  and the twist coupler  105 . These examples, however, are non-limiting. Also, the opener  104  can have two steps of thicknesses: an outer rim for major torque support and an inner portion for securing the twist coupler  105  to the outer rim. In some implementations, the inner portion of the opener  104  can be of the same thickness as the rib structure  107 , and does not contact the sidewalls of the tip  103 . In the implementation illustrated in  FIG. 1 , the edges of the opener  104  are flush with the bottom of the tip  103  to facilitate the opening operation. The edges of the opener  104  is also flush or contiguous with the rib structure  107  of the body  101 . 
         [0027]    The bottom of the body  101  can include a dimension  108 . The dimension  108  can include the diameter of the body  101  and a side extrusion step from the rib structure  107 . To enhance portability and miniaturize the ampoule  100 , the dimension  108  can be between about 15 mm and 25 mm (e.g., about 22 mm), and the extrusion portion of the rib structure  107  can be, for example, 1.5 mm. The diameter of the body  101  can be of any other values that, given certain length, can contain enough fluid for a one-time treatment, such as rinse, lavage, moisturize, etc. Various dimensions of the ampoule  100  also can exist. For example, the overall length  106  of the ampoule  100  can be between about 80 mm and 120 mm (e.g., 99 mm). The overall length  106  can be of any other value that fits within conventional purses, backpacks, briefcases, or other daily carry items. 
         [0028]      FIG. 1B  is a schematic top view of the ampoule  100 , as shown in  FIG. 1A . In some implementations, the body  101 , the tip  103 , and the twist coupler  105  have circular cross section shape at various diameters. For example, the cross section of the twist coupler  105  may be a circular shape that has a diameter between about 4 and 10 mm (e.g., 6.35 mm). The maximum cross section of the tip  103  may have a diameter between about 10 and 20 mm (e.g., 15 mm). The cross section of the body  101  may have a diameter between about 15 and 25 mm (e.g., 22 mm) as the dimension  108 . It can be seen from the top view that the opener  104  and the rib structure  107  align in the same plane that symmetrically divide the ampoule  100 . Although the general cross section of the ampoule  100  is circular shape in this example, the cross section may be, in some implementations, a different practical shape, such as an elliptical shape for ease of applying pressure, a triangular shape for packaging reasons, a diamond shape for both ease of applying pressure and packaging reasons, and/or a combination of different shapes at different cross section locations. 
         [0029]      FIG. 2  is a schematic side view of the ampoule  100 , as shown in  FIG. 1A . The side view shows additional structures of the ampoule  100 . For example, the bottom of the body  101  is shaped for reinforcement and easy mold release that includes a concave surface  212  in the extrusion direction of the rib structure  107 . Also, as shown in  FIG. 2 , the twist coupler  105  is attached to the tip  103  at a circular tangential portion  214  that acts as a plug or sealer for sealing the aperture  109 . Further, in the example shown, the outer portion of the opener  104  is thicker than the rib structure  107 .  FIG. 2  further shows a dimension  202  to denote the diameter of the body  101 , a dimension  204  to denote the thickness of the rib structure  107 , a dimension  206  to denote the thickness of the opener  104 , and a dimension  208  to denote the diameter of the twist coupler  105 . 
         [0030]    The circular tangential portion  214  connects the twist coupler  105  to the sealing aperture  109  by a cross section that has sufficient strength to maintain structural integrity during transportation (i.e. maintain shape under bending and tension loading conditions) and can be severed under shear stress in a twisting motion. In the example shown in  FIG. 2 , the circular tangential portion  214  has a low aspect ratio (e.g., height to diameter ratio is very small), allowing for very small moment arm for bending deformation. This shape profile enables resistance against bending failure modes. The circular tangential portion  214  is affixed to the opener  104  that allows for a large moment arm to be applied by user (at least about twice as large as the sealing cross section diameter). This allows for more material to be in contact at the sealing cross section between the circular tangential portion  214  and the aperture  109 , better resisting tension or compression deformation. 
         [0031]    To expose the aperture  109 , a moment is applied to the opener  104  that is affixed to the twist coupler  105  by circumferential connection. The moment creates a shear stress concentrated at the circular tangential portion  214  while the connection between the twist coupler  105  and the opener  104  is under tension. Such as tearing apart a piece of paper is much easier than pulling apart a piece of paper, the cross section between the aperture  109  and the circular tangential portion  214  will fail or break before any other locations. This breaks apart the opener  104  and the tip  103  and exposes the aperture  109 . The twist coupler  105  may include inner side walls that conform with but do not contact sidewalls of the tip  103 . 
         [0032]    In some implementations, the circular tangential portion  214  may have a donut-shape, a tire shape, or any other low aspect ratio cylindrical shapes that enable separation from the aperture  109  with shear stress. In some implementations, the circular tangential portion  214  may be of the same cross section shape as the aperture  109  and/or the tip  103 . 
         [0033]    The concave surface  212  at the bottom of the body  101  illustrated in  FIG. 2  has multiple purposes, such as reinforcing the structural integrity of the body  101 , enabling faster manufacturing process, allowing user to recognize the ampoule orientation, etc. In some implementations, the concave surface  212  creates a strengthening profile of the bottom of the body  101  by increasing the moment of inertia of the structure. This is the similar principle applied to most thin-walled bottles that use the shape instead of materials to achieve certain desired strength. The concave surface  212  also creates a strong local structure of the body  101  to withstand relatively large external loads. This may facilitate the manufacturing process when the body  101  is to be handled by various machines. 
         [0034]    Various dimensions of the ampoule  100  are possible and illustrated in  FIG. 2 . For example, the diameter  202  of the body  101  can be in the range between 12 and 30 mm (e.g., about 20.5 mm). The diameter  202  can be of any other values that, given certain length, can contain enough fluid for a one-time treatment. In some implementations, the thickness  204  of the rib structure  107  can be in the range of 1 to 2 mm (e.g., about 1.4 mm). In some implementations, the thickness  204  can be of any other values so that, when loaded to twist open the ampoule  100 , the rib structure  107  can maintain the original shape without excessive deformation. 
         [0035]    In some implementations, the thickness  206  of the opener  104  can be in the range between 2 and 3 mm (e.g., about 2.4 mm). In some implementations, the thickness  206  can be at least 1 mm thicker than the thickness  204 , or of any other values that gives the opener  204  enough structure integrity to twist open the coupler  105 . In some implementations, the diameter  208  of the circular tangential portion  214  can be in the range between 3 and 8 mm (e.g., about 6.35 mm). The diameter  208  can be of any other values sufficient to provide a secure seal to the aperture  109 . 
         [0036]      FIG. 3  is a schematic cross-sectional view of the ampoule  100 . As shown in  FIG. 3 , portion of the body  101  is shown with a line  302  indicating the fill-up line for the fluid contained in the body  101 . At about 20 ml fluid volume and about 20 mm body diameter, the line  302  can be about 66 mm from the bottom of the body  101 . The position of the line  302  can change if a different fluid volume is to be filled and the body  101  is of a different diameter or size. The length  306  of the neck  102  can be in the range between 2 and 8 mm (e.g., about 6.4 mm), and can be of any other values that provides the rib structure  107  enough room for holding the ampoule  100 . 
         [0037]    In some implementations the rib structure  107  at the body  101  can be flush or contiguous with the rib structure  107  at the opener  104 . In some implementations, the bottom diameter  304  of the tip  103  can be in the range between 10 and 20 mm (e.g., 14.9 mm), while the top diameter  312  of the tip  103  can be in the range between 3 and 8 mm (e.g., 6.35 mm), or the same value as the diameter  208 . In some implementations, the diameter  308  of the aperture  109  can be in the range between 1.5 and 3.5 mm (e.g., 2.54 mm). In some implementations, the overall structure can be of a uniform thickness  310 , which can be in the range between 0.3 and 0.8 mm (e.g., 0.65 mm). 
         [0038]    As discussed above, the ampoule  100  can be made of a thermoplastic polymer, or thermoplastics. Most thermoplastics are high-molecular-weight polymers whose chains associate through weak Van der Waals forces (e.g. polyethylene); stronger dipole-dipole interactions and hydrogen bonding (e.g. nylon); or even stacking of aromatic rings (e.g. polystyrene). For example, the ampoule  100  can be made of acrylonitrile butadiene styrene, acrylic, celluloid, cellulose acetate, cyclic olefin copolymer, ethylene-vinyl acetate, ethylene vinyl alcohol, fluoroplastics, lonomers, Kydex, liquid crystal polymer, polyoxymethylyne, polyacrylates, polyacrylonitrile, polyamide, polyamide-imide, polyaryletherketone, polybutadiene, polybutylene, polybutylene terephthalate, polycaprolactone, polychlorotrifluoroethylene, polyethylene terephthalate, polycyclohexylene dimethylene terephthalate, polycarbonate, polyhydroxyalkanoates, polyketone, polyester, polyethylene, polyetheretherketone, polyetherketoneketone, polyetherimide, polyethersulfone, chlorinated polyethylene, polyimide, polylactic acid, polymethylpentene, polyphenylene oxide, polyphenylene sulfide, polyphthalamide, polypropylene, polystyrene, polysulfone, polytrimethylene terephthalate, polyurethane, polyvinyl acetate, polyvinyl chloride, polyvinylidene chloride, styrene-acrylonitrile, and/or a combination of these, or any other appropriate thermoplastics. 
         [0039]    In some implementations, the ampoule  100  can be made of a thermosetting polymer, or thermoset. Thermoset is a polymer material that cures irreversibly through heat (generally above 200° C. (392° F.)), through a chemical reaction (two-part epoxy, for example), or irradiation such as electron beam processing. In some instances, the ampoule  100  can be made of vulcanized rubber, bakelite, duroplast, melamine resin, phenol formaldehyde, urea formaldehyde, melamine formaldehyde, polyester, epoxy, isoprene crosslinked with sulphur, neoprene, trihydroxymethylsilane, and/or a combination of these, or any other appropriate thermosetting polymers. 
         [0040]    In some implementations, the ampoule  100  can be coated internally with a layer of epoxy resin to prevent reaction between the fluid and the body material. For example, if the ampoule  100  is coated with a layer of metal for light isolation or uses a metallic material for construction, then a layer of epoxy resin can provide isolation of the fluid and prevent undesired materials leaching into the liquid or solution contained in the body  101 . 
         [0041]    In some implementations, the ampoule  100  can be transparent overall, or in a portion such that remaining portion of fluid may be monitored. For example, the ampoule  100  may be made of a clear thermoplastic polymer, and/or a clear thermosetting polymer. 
         [0042]    In some implementations, the ampoule  100  can use various materials for the body  101 , the neck  102  and the tip  103 . For example, the body  101  can use a thermoplastic polymer while the neck  102  and the tip  103  can use a thermosetting polymer. A variation of material in different parts of the ampoule  100  can improve durability, provide convenience to use, or enhance other characteristics of the ampoule  100  such as gripping. 
         [0043]      FIG. 4A  is a one schematic view of the ampoule  100  before removing the opener  104 , and  FIG. 4B  is another schematic view of the ampoule  100  after removing the opener  104 . As shown in  FIG. 4A , the opener  104  and the twist coupler  105  are attached to the tip  103 . The rib structure  107  allows users to conveniently hold and grip the body  101  and avoid slipping motion in the rotational direction. Upon removing the opener  104 , the aperture  109  is revealed. 
         [0044]    In some implementations, a user should be in a upright position before using the opened ampoule  100 , which is shown in  FIG. 4B . The head of the user can be tilted to one side slightly. After placing the tip  103  into one nostril, the user can press gently to dispense a few drops or a small quantity for moisture or squeeze to expel a larger quantity for nasal irrigation. After one use, the whole ampoule  100  can be discarded, along with unused solution. The ampoule  100  can be used to contain fluid that is a drug-free, preservative-free, sterile nasal saline solution. The solution can sooth and moisturize dry and congested noses for babies, children and adults. In the 20 ml volume implementation shown in  FIG. 3 , the ampoule  100  is convenient for home, nursery, playground, school, air travel, hotel room and hospital use. A few drops of saline can moisturize, while squeezing a larger quantity can deliver a gentle low pressure low volume nasal rinse directly into the nostril for stronger results. 
         [0045]      FIG. 5A  is a schematic view of a second ampoule implementation  500 . In this implementation, the second ampoule  500  includes a body  510  and a cap  550 . The body  510  can be a fluid container (e.g. a bottle, can or other container) that securely stores fluid and allows users to apply pressure (e.g. to the container) to expel the stored fluid. For example, the body  510  can be made of thermoplastic polymers, thermosetting polymers, or any other appropriate materials that allows for deformation in order to pressurize the bottle for fluid release. In some implementations, the ampoule  500  can be pressurized for maintaining shape during transportation. In some implementations, the body  510  is a cylindrical shape of a uniform diameter. In some implementations, the diameter can vary along its longitudinal axis, for example, a tapered shape, a curved shape, a diamond shape, or other shapes. The body  510  can be a thin-walled structure of uniform thickness and/or variable thickness for functional requirements. For example, to facilitate deformation, some locations on the body  510  can be thinner than the rest. As another example, other locations on the body  510  can be thicker for structural reinforcement, such as a portion at or near the bottom of the ampoule  500 . Grooves or depressions can be included in the body to facilitate gripping by the human hand. 
         [0046]    The body  510  may include a rib structure  560  to facilitate holding or gripping of the body  510  to avoid slipping motion. The rib structure  560  may be flush or contiguous with edges of the opener  520 , or may be only extended to a functional portion around the body  510 . The rib structure  560  may extend from a bottom portion of the tip to a bottom portion of the body  510 . 
         [0047]    As shown in  FIG. 5A , the cap  550  is a conical needle head structure for securely sealing the ampoule body  510  and allowing for reuse. The cap  550  includes two structural features besides the needle head shape: a pulling support  520  and a sealing support  530 . The pulling support  520  enables user to apply a tension force to separate the cap  550  from the body  510 . The pulling support  520  may be a sudden increase in diameter of the conical shape of the cap  550 . This resulting step structure allows user&#39;s fingers to engage with the cap  550 . The sealing support  530  is an extruding structure near the middle location of the cap  550 . The sealing support  530  engages with the sealing end  540  at the tip of the body  510 . The sealing end  540  may be a donut, a tire or other inner grooved shape that couples with the sealing support  530  under a predetermined stress that seals the aperture of the body  510 . 
         [0048]    In some implementations, the ampoule  500  can be made of a thermoplastic polymer, or thermoplastics. Most thermoplastics are high-molecular-weight polymers whose chains associate through weak Van der Waals forces (e.g. polyethylene); stronger dipole-dipole interactions and hydrogen bonding (e.g. nylon); or even stacking of aromatic rings (e.g. polystyrene). For example, the ampoule  500  can be made of acrylonitrile butadiene styrene, acrylic, celluloid, cellulose acetate, cyclic olefin copolymer, ethylene-vinyl acetate, ethylene vinyl alcohol, fluoroplastics, lonomers, Kydex, liquid crystal polymer, polyoxymethylyne, polyacrylates, polyacrylonitrile, polyamide, polyamide-imide, polyaryletherketone, polybutadiene, polybutylene, polybutylene terephthalate, polycaprolactone, polychlorotrifluoroethylene, polyethylene terephthalate, polycyclohexylene dimethylene terephthalate, polycarbonate, polyhydroxyalkanoates, polyketone, polyester, polyethylene, polyetheretherketone, polyetherketoneketone, polyetherimide, polyethersulfone, chlorinated polyethylene, polyimide, polylactic acid, polymethylpentene, polyphenylene oxide, polyphenylene sulfide, polyphthalamide, polypropylene, polystyrene, polysulfone, polytrimethylene terephthalate, polyurethane, polyvinyl acetate, polyvinyl chloride, polyvinylidene chloride, styrene-acrylonitrile, and/or a combination of these, or any other appropriate thermoplastics. 
         [0049]    In some implementations, the ampoule  500  can be made of a thermosetting polymer, or thermoset. Thermoset is a polymer material that cures irreversibly through heat (generally above 200° C. (392° F.)), through a chemical reaction (two-part epoxy, for example), or irradiation such as electron beam processing. In some instances, the ampoule  500  can be made of vulcanized rubber, bakelite, duroplast, melamine resin, phenol formaldehyde, urea formaldehyde, melamine formaldehyde, polyester, epoxy, isoprene crosslinked with sulphur, neoprene, trihydroxymethylsilane, and/or a combination of these, or any other appropriate thermosetting polymers. 
         [0050]    In some implementations, the ampoule  500  can be coated internally with a layer of epoxy resin to prevent reaction between the fluid and the body material. For example, if the ampoule  500  is coated with a layer of metal for light isolation or uses a metallic material for construction, then a layer of epoxy resin can provide isolation of the fluid and prevent undesired materials leaching into the liquid or solution contained in the body  510 . 
         [0051]    In some implementations, the ampoule  500  can be transparent overall, or in a portion such that remaining portion of fluid may be monitored. For example, the ampoule  500  may be made of a clear thermoplastic polymer, and/or a clear thermosetting polymer. 
         [0052]    In some implementations, the sealing support  530  may be made of a material different from that of the body  510 , such as metal, for preferred elastic modulus and reliability. The sealing support  530  may be made in a shape that conforms to the inner chamber of the sealing end  540 . The shape of the sealing support  530  may experience substantial elastic deformation during the coupling and/or decoupling process with the sealing end  540 . In some cases, the sealing support  530  may be made of a foil of stainless steel forming a donut shape to couple with the sealing end  540 . 
         [0053]      FIG. 5B  is a schematic cross-sectional view along the longitudinal axis of the second ampoule implementation. This cross-sectional view shows details about the engagement between the cap  550  and the body  510 . The sealing end  540  at the tip of the body  510  may have two inner edges that conform to the tapered needle cap  550 . The upper edge of the sealing end  540  may provide a sealing force closing the cap  550  towards the lower edge of the sealing end  540 . The cap  550  can be a thin-walled structure of approximate uniform thickness. The cap  550  may experience substantial elastic deformation during the coupling and/or decoupling process with the body  510  at the sealing end  540 . 
         [0054]    A number of embodiments of the disclosure have been described. Nevertheless, it will be understood that various modifications can be made without departing from the spirit and scope of the disclosure. For example, instead of attenuating a fast stream of liquid into a gentle flow, a mist exiting the actuator can be transformed into a gentle cleansing stream of fluid. Accordingly, other embodiments are within the scope of the following claims.