Abstract:
A device for stimulation via electric and magnetic fields is provided. The autonomic/vegetative nervous system can be controlled by signals in the frequency ranges of 0.05 to 0.15 Hz and 0.15 to 0.30 Hz, respectively. By addition of characteristic sinusoidal oscillations between the head and a peripheral area with the corresponding low-frequency sympathetic or parasympathetic control frequency as base oscillation and with application-typical EEG frequencies and higher-frequency sinusoidal oscillations in the range of ca. 250 to 1500 Hz, characteristic stimulation programs are established. These are applied by field applicators in the upper body area and in the lower body. The associated mat applicators distribute field energy. The field applicator is equipped with a combination of a magnetic-field-generating coil arrangement and an electrode arrangement generating the electric field. The electrode generating the electric field can at the same time be designed as a magnetic-field-generating coil.

Description:
BACKGROUND 
     The invention relates to a device for stimulation via electric and magnetic fields, and field applicators for this purpose. 
     When biological processes are caused or influenced by natural electro-magnetic fields, as shown for example by Koenig [Unsichtbare Umwelt. Der Mensch im Spielfeld elektromagnetischer Kraefte. Eigenverlag Herbert L Koenig, Munich 1986], Marino [Modern Bioelectricity, Marcel Dekker, New York and Basel 1988] and Krauss [QRS-Magnetfeldtherapie—Gegenwart und Zukunft (Plenary address); conference volume “QRS-Magnetfeldtherapie—Gegenwart und Zukunft, 1. Internationales Symposium Quantenmedizin in Forschung und Praxis. Darmstadt/Weiterstadt Apr. 2, 2001; “Die natuerlichen elektromagnetischen Signale in unserer Umwelt und deren Stimulation als QRS®-Magnetfeldtherapie”, lecture on the Northern German conference for complementary medicine, Jun. 22-23, 2002 Wilhelmshaven, as well as “Die Mikrostrom-CellVAS®-Therapie” (publication of the company Software+Systeme Erfurt GmbH/Germany 2004)], it is possible to largely reproduce nature using specific fields and in case of an existing deficit hereby stimulate humans and animals. On this note the hypothesis must be assessed, formulated by Itil [Quantitative pharmaco-electroencephalography. Use of computerized cerebral biopotentials in psychotropic drug research. In: Itil, T. M. (Ed.): Modern Problems of Pharmacopsychiatry, Vol. 8: Psychotropic Drugs and the Human EEG. Karger, Basel 1974] as well as Fink [Cerebral electrometry—quantitative EEG applied to human psycho-pharmacology. In: Dolce, G. and H. Kuenkel (Eds): CEAN-computerized EEG-analysis. Fischer, Stuttgart/New York 1975] and proven, among others, via pharmaceutical EEG (Pharmako-EEG) [Herrmann, W. M. and E. Schaerer: Das Pharmako-EEG. Grundlagen, Methodik, Anwendung. Landsberg/Lech/Germany: ecomed 1987 (ISBN 3-609-64170-3)], according to which
         equivalent EEG-modifications (EEG-electro encephalogram) lead to the same stimulus effects and/or   equivalent stimulus effects are connected to the same EEG-modifications.       

       FIG. 1  shows the previously known primary frequency ranges of physical stimulation. 
     Fournier [Description des installations dúne station dénregistrement des variations tre&#39;s rapides du champ magne&#39;tique terrestre; extrait des Comptes Rendus des séances de l&#39;Acade&#39;mie des Sciences, t. 251, p. 671-673 séance due 1 er  aout 1960] reports on the terrestrial magnetic field measurements performed, in which oscillations were determined with a range of variation of the allocated periods lasting from 30 seconds (=0.03 Hz) to 0.025 seconds (=40 Hz). The upper frequency limit is here equivalent to the EEG and EKG (EKG—electrocardiogram). Koenig [Unsichtbare Umwelt. Der Mensch im Spielfeld elektromagnetischer Kraefte. Eigenverlag Herbert L. Koenig, Munich 1986] has discovered that magnetic fields connected to the activity of the heart have a frequency range from 0.1 to 40 Hz. Accordingly, the upper frequency limits are identical for the earth magnetic field, EKG, and EEG. This may also apply to the lower frequency limit, however no publications in this regard have been found. 
     The spectrum of amplitudes deduced by Fournier from the measurements of the terrestrial magnetic field showed a resonance point at the Schumann and/or EEG-α-frequency 10 Hz. However, oscillations having periods lasting 4.5 seconds were dominant, which is equivalent to a frequency of 0.22 Hz. This value also coincides with the field of human respiration and/or the parasympathetic nervous system as a component of the autonomic nervous system, as discernible from Schmidt and Thews [Human Physiologie. Second, Completely Revised Edition, Springer Berlin Heidelberg New York 1989]. Accordingly, the mean breathing frequency of adults at rest amounts to 14 breaths/min. (=0.23 Hz), with variations occurring ranging from 9.18/min [=0.15 . . . 0.3 Hz]. 
     Persinger [Possible Cardiac Driving by an External Rotating magnetic Field. Int. J. Biometeor. Vol. 17, No. 3, pp. 263-266, 1973] examined the possibility to control the activity of the heart of rats by an external magnetic field rotating at 0.5 Hz with an intensity of 10-20 Gauss. Here, significantly longer RR-intervals developed than in the control groups (RR-interval . . . amount of time deduced from the peaks of two successive R-waves in the EKG, which is equivalent to the duration of a cardiac period and thus the reciprocal heart frequency). This is the obvious expression for an activation of the parasympathetic nervous system, which as commonly known reduces the heart frequency [Thews, G et R Schmidt: Human Physiologie. Second, Completely Revised Edition, Springer Berlin Heidelberg New York 1989], also in a rat. 
     Friedmann et al. [Friedmann, H., R. O. Becker and C. H. Bachmann: Effect of Magnetic Fields on Reaction Time Performance. Nature Vol. 213, no. 5079, pp. 949-950, 1967] examined the effectiveness of extremely slow oscillations of magnetic fields on the reaction time of humans. These results were found:
         Static fields with a strength of 0.5 mT and/or 1.7 mT cause no statistically proven influence.   A static field in combination with an alternating field showed statistically proven results, though: The test persons treated with a field having a parasympathetic—frequency 0.2 Hz had a longer reaction time in reference to the sympathetic—frequency 0.1 Hz.       

     The latter results show that the frequency 0.1 Hz, that can change the peripheral micro-circulation, coincides with the known Traube-Hering wave as well as an activation of the sympathetic nervous system, while 0.2 Hz correlates to the respiratory frequency and/or the parasympathetic nervous system. 
     As known from the human physiology [Thews, G et R Schmidt: Human Physiologie. Second, Completely Revised Edition, Springer Berlin Heidelberg New York 1989], all organs of the body, except for the skeletal muscles, are innervated by the vegetative/autonomic nervous system. In addition to influencing the internal organs humorally, there is a second way for controlling cell functions: The vegetative nervous system via its component sympathetic and parasympathetic nervous system, which can be influenced by signals of the frequency ranges 0.05 . . . 0.15 Hz and/or 0.15 . . . 0.30 Hz [Thews, G et R Schmidt: Human Physiologie. Second, Completely Revised Edition, Springer Berlin Heidelberg New York 1989]. 
     In this way, the vegetative nervous system becomes a “control system” for the peripheral vessels, heart, bronchia, intestines, kidney, genitalia, etc. 
     SUMMARY 
     Based on the above-mentioned facts, the object of the invention is therefore to provide a further developed device for stimulation via electric and magnetic fields and field applicators particularly suitable for this purpose, with the device having to ensure that a quasi-control of the vegetative nervous system can occur. 
     This object of the invention is attained according to the features of claim  1 , with the sub-claims at least representing beneficial embodiments and further developments. 
     According to the invention, instead of a fixed frequency 0.1 and/or 0.23 Hz, the overall sympathetic [0.05 . . . 0.15 Hz] or parasympathetic [0.16 . . . 0.30 Hz] frequency range is used in the form of a stimulation frequency impressed from the outside wobbled or swept successively in an arbitrarily fine graduation. Here, beneficially the steps for these ranges are predetermined 0.05; 0.06; 0.07; 0.08; 0.09; 0.1; 0.11; 0.12; 0.13; 0.14; 0.15 Hz and/or 0.16; 0.17; 0.18; 0.19; 0.20; 0.21; 0.22; 0.23; 0.24; 0.25; 0.26; 0.27; 0.28; 0.29; and 0.30 Hz. Here, a respective stimulation period of 30 seconds is sufficient. The mean values of 0.1 Hz (sympathetic nervous system, blood pressure periods, Traube-Hering oscillations) and/or 0.23 Hz (respiration, parasympathetic nervous system) are impressed upon the autonomic nervous system for a longer period of time, approx. 4 minutes. 
     As experience teaches, a continuous meteorological collection of blood pressure and/or respiratory periodic occurs as well as a constant comparison to the respective target values 0.1 and/or 0.23 Hz. Similar to technical regulatory measures, by stimulating the nervous system with an alternating field of electric or magnetic energy it is tried for the actual values measured to approximate the optimal target values. 
     According to the invention, this allows a stimulating control of the human autonomic nervous system using the coupled alternating fields including frequencies and/or frequency ranges of approx. 0.1 and/or 0.23 Hz. 
     In the area of the spinal cord as an essential component of the central nervous system, there are decisive sections for a potential coupling of the information parameters, primarily for the sympathetic and the parasympathetic nervous system via physical stimulation, which according to the invention can be stimulated via field applicators designed with an appropriate structure. 
     This is achieved, among other things, in that the field applicator system is designed for the upper body such that a concentration of the magnetic flux is adjusted to the center of the upper body of the proband (area of the central nervous system). Also adjusted to the physiological conditions of humans, the applicator system allocated to the lower body is designed such that the distribution of the field energy occurs to both leg areas, with their centers having a certain distance from each other, and thus two field-strengths maxima develop. 
     Typical cardiovascular stimulation programs can be produced by combining a positive or negative E-field component with a control frequency of the autonomic nervous system as well as other known stimulation frequencies. 
     Here, according to the invention, an E-field component shall define an electric field created between the foot and the head area. Unlike magnetic fields, this E-field stimulates potential differences. In order to combine the advantages of the stimulation via electric potentials with the effects of magnetic fields a field applicator according to the invention is provided with a combination of a coil arrangement creating a magnetic field and an electrode arrangement creating the electric field. Here, the electrode creating the electric field can simultaneously be embodied as a coil creating a magnetic field. 
     This represents a principal difference from conventional stimulation realizations via magnetic fields, because in the latter, in addition to the alternating field, a temporarily unchanged portion (DC-portion) can be generated in the stimulation signal, however creating only a constant magnetic field and no potential difference between the area near the head and the cardiovascular periphery. 
     While the basic structures of previous stimulus-signals are similar in their principles and for example comprise a meandering function with a rising e-function and/or an inclining, overlapping sinus, thus e.g., allowing frequencies in the EEG-frequency range by an appropriate combination of a basic function and a pulse package, an addition of determined sinusoidal oscillations according to the invention can be used with an appropriately low-frequency sympathetic or parasympathetic control frequency as the basic oscillation. 
     This control frequency, in addition to the E-field component, is interfered with selected n-frequencies of the EEG-range as well as m-frequencies causing biochemical reactions. For example, according to the invention it has been learned via signal-frequency optimizations performed that an aggregation of erythrocytes occurring in the blood-dark field can be dissolved primarily by frequencies ranging from approx. 250 to 1500 Hz. According to the invention, a Fourier sequence with a base oscillation of approx. 250 Hz as well as harmonic oscillations of approx. 500, 750, 1000, 1250, 1500, . . . Hz have been determined as optimal ratios, when the amplitudes of these harmonic oscillations amount to relative portions of ½, ⅓, ¼, ⅕, ⅙, . . . and an overall signal phase shift is realized of 180°. When this electric component, by which the respective magnetic field shall cause the normalization of the erythrocyte aggregation, is called 
     i IIS (5) [iis . . . ion injection signal], in case of a basic oscillation of 250 Hz it is yielded, for example, (A . . . amplitude of the basic oscillation 250 Hz):
 
 I   IIS ( t )=− A [sin 2π250 t+ 0.5 sin 2π500 t+ 0.33 sin 2π750 t+ 0.25 sin 2π1000 t+ 0.2 sin 2π1250 t+ 0.17 sin 2π1500 t+ . . . ] 
 
     The signal created in this manner is interfered with the known frequencies of the EEG—range as well as the appropriate control frequency of the autonomic nervous system. Due to the fact that the erythrocytes, particularly their membrane, represent an oscillation system and the optimal frequency (resonance frequency) amounts to approximately 1 kHz, such a separation of erythrocytes can occur by the resonance effect at the membrane. In case of a (pathologic) erythrocyte aggregation the flow features of the blood change. Furthermore, the resonance frequency of this system is reduced by dampening occurring, as known from the theory of (linear) systems. According to the invention, the potential frequency detuning of blood cells is compensated such that the frequency portions included in the signal can pass a defined band width, thus oscillate slightly around a mean frequency. 
     The fields provided for the stimulation are generated via a special device for creating the fields. This device exchanges the electric signals created in the signal creation device into the energy forms provided for the stimulation. Here, various devices in the form of simple electric coils are known, integrated in a mat applicator. Here, various electric coils are arranged such that they apply a field predominantly induced by a magnetic field. Due to the fact that the operation of the device occurs at frequencies below 1 MHz, almost no electric fields are generated by the known device. The equilibrium of the electric and the magnetic field known from electromagnetic science only develops at a distance of far more than the wavelengths, which even at a frequency of 1 MHz still amounts to approx. 300 m. In the immediate application range of the device the known devices create therefore almost no electric field components at all. 
     As stated above, the stimulation is particularly effective in combinations of electric and magnetic fields. According to the invention, the device is designed for creating fields from various individual coils or coils in combinations with electrically conductive grids or surfaces is designed for allowing both the feeding of electric currents as well as voltages. 
     Particularly by the cooperation of the elements it is possible to cause the combination of fields to become effective. 
    
    
     
       BRIEF DESCRIPTION OF THE DRAWINGS 
       The invention is explained in greater detail using exemplary embodiments and figures. Shown here are: 
         FIG. 1  shows characteristic stimulation frequencies of electric and magnetic fields [from Krauss, M: “Die natuerlichen elektromagnetischen Signale in unserer Umwelt und deren Stimulation aus QRS®-Magnetfeldtherapie.” Lecture on the Northern German conference for complementary medicine, 22-23 Jun. 2002, Wilhelmshaven], 
         FIG. 2  is a view of a simple device for creating an electric field combined with a magnetic field by transforming electric signals, with the electric field following the magnetic field, 
         FIG. 3  is an expanded circuit diagram of the device for creating an electric field combined with a magnetic field, with the electric field being controllable independent from the magnetic field, 
         FIG. 4  is a view of an expanded device for creating an electric field combined with a magnetic field, 
         FIG. 5  is a view of a special embodiment of the device for creating an electric field combined with a magnetic field, 
         FIG. 6  is a graph showing the distribution of the electric field between the upper and the lower coil in a device according to  FIG. 3 , 
         FIG. 7  is a graph showing the distribution of the electric field between an electrode and a coil system in an arrangement according to  FIG. 4  or  5 , 
         FIG. 8  is a graph showing the progression of the magnetic flux density over a coil arrangement adjusted to the physiological conditions, 
         FIG. 9  is a view of an embodiment of the device for creating an electric field combined with a magnetic field according to the embodiment of  FIG. 5 , 
         FIG. 10  is a diagram of a simple device for checking the functionality of the device for stimulating probands via special electric and magnetic fields as well as optimized field applicators, 
         FIG. 11  is a graph of the characteristic progression of peripheral blood circulation parameters, deducted from the non-invasive NIRP-method of the measuring site finger pad in a 40-year old normal probands, with changes of the E-field components of a stimulation program, in the exemplary embodiment “Vitality”, 
         FIG. 12  is a graph of an oscillation period of low-frequency sympathetic (a) as well as parasympathetic (b) control frequency as the basic oscillation of a corresponding stimulation program, 
         FIG. 13  is a graph of the periodic progression of a defined higher-frequency III-function i IIS (t) [iis . . . ion injection signal] with the periods from 4 ms=250 Hz and the frequencies 250, 500, 750, 1000, and 1250 Hz, if the respective amplitudes of these oscillations have the relative portions 1, ½, ⅓, ¼, ⅕, ⅙, 
         FIG. 14  is photographs of a result, to be a generalized exemplary embodiment, of blood dark area images taken from a 55-year old diabetes patient prior, after 2, 4, and 12 minutes of stimulation with the IIS-function i IIS (t) according to  FIG. 13 , 
         FIG. 15  is graphs of the characteristic oscillation frequencies, interfered with the parasympathetic control frequencies of 0.25 Hz, for a stimulation program “Relax” as the exemplary embodiment:
     a) a basic oscillation 0.25 Hz with a relative amplitude of 50% and a relax-reference frequency (EEG-delta frequency) of 2 Hz at 100% amplitude ratio,   b) an EEG-alpha frequency of 100 Hz with 50% and 100 Hz with 40% of the reference signal (reference frequency) of 2 Hz,   c) an overall signal from adding a) and b) as well as i IIS (t) [see  FIG. 13 ] for the stimulation period of 4 s, equivalent to the period of the basic oscillation of 0.25 Hz=4 s,   

         FIG. 16  is graphs of the characteristic oscillation frequencies interfered by the parasympathetic control frequency of 0.25 Hz for a stimulation program “Vitality” representing the exemplary embodiment:
     a) a vitality reference frequency of 10 Hz (EEG-alpha frequency) at 100% amplitude ratio as well as 100 Hz at 40% amplitude ratio,   b) an overall signal from adding a) as well as 0.25 Hz (50% amplitude ratio, see  FIG. 12 ) and i IIS (t) [see  FIG. 13 ] for the stimulation period of 4 s, which is equivalent to the period of the basic oscillation of 0.25 Hz=4 s, and   

         FIG. 17  is graphs of the characteristic oscillation frequencies, which are interfered with the sympathetic control frequency 0.1 Hz, for a stimulation program “Performance” representing an exemplary embodiment:
     a) a performance reference frequency of 10 Hz (EEG alpha-frequency) at 100% amplitude ratio and 20 Hz at 70% amplitude ratio as well as 100 Hz at 40% amplitude ratio,   b) an overall signal from adding a) as well as 0.1 Hz (50% amplitude ratio, see  FIG. 12 ) and i IIS (t) [see  FIG. 13 ] for the stimulation period of 10 s, which is equivalent to the period of the basic oscillation 0.1 Hz-10 s.   

     
    
    
     DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS 
     The device according to  FIG. 2  is characterized in that the applicator comprises two coil systems  20  and  30 , which are spatially arranged such that, on the one hand, a concentration of the effects of the different magnetic fields on the various areas of the effect is achieved and, on the other hand, a potential difference between the coils also leading to the formation of a specific electric field. 
     The potential difference is created by the voltage dropping via a resistor  40 , which is switched between the connector  22  and the connector  31 . This circuit achieves that the electric field follows the magnetic field. When the current to create the magnetic field is interfered by direct current (DC-component), additionally the formation of a constant E-field is achieved. 
     In  FIG. 2  two coil systems  20  and  30  are shown with connectors  21  and  22  for the coil system  20  as well as the connectors  31  and  32  for the coil system  30 . Using the power source  50 , a current  51  is fed to the coil system such that the current first flows through the coil  20 , subsequently over the resistor  40  switched between the connectors  22  and  31 , is guided into the coil system  30 , and subsequently flows back to the power source via the connector  32 . The effect of the electric field develops by the voltage drop via the resistor such that an electric potential difference is created between the coil system  20  and  30 . The current flow in the coil systems in turn creates the effect of the magnetic field. The current  51  is modulated by the power source  50  in the intensity using the above-described frequencies, so that the electric and magnetic fields can unfold their effect in the manner described. 
     The arrangement according to  FIG. 3  shows an expansion of the functionality of the example according to  FIG. 2  by an amended switching. 
     This allows to separately controlling both the electric field component as well as the magnetic field component. In addition to the improvement of the application of the device, additionally better energy utilization is achieved, because the loss by the Ohm resistance is omitted. Additionally, the direct (current) portion in the control signal for the magnetic field component can be omitted, because this DC-portion can be used in an energy saving manner for the electric field. 
       FIG. 3  shows in detail: two coil systems  20  and  30  with connectors  21  and  22  for the system  20  and  31  and  32  for the system  30 . By the power sources  50  a current, modulated according to the attempted goal, is fed to the coil system, here system  30  is shown. Furthermore, the power source  51  feeds a current into the into the system  20  and creates a second magnetic field in the effective range of this coil system, which can also be controlled by the separate power source, independent from the first coil system with regard to its intensity or composition of frequency. Using a power source  60 , an electric potential difference is created between both coil systems, so that an electric field can form between the two coil systems. 
       FIG. 4  discloses an expanded device for creating an electric field combined with a magnetic field, with independent electrode systems being provided for the electric field and the magnetic field, and the magnetic field being created by a single power source and the electric field by a single voltage source. 
     Two advantages develop from this mat-applicator arrangement. On the one hand, the coil system creating the magnetic field can be designed rather freely and can be oriented optimally for achievement of goals. The electric field can be optimized in the same manner so that both fields can be embodied independent from each other. Another advantage in reference to the arrangements according to  FIGS. 2 and 3  is the concentration of the electric field on the side of the applicator that the application originates from. The back thereof shields the electric field such that, on the one hand, no interferences can occur, for example by electric wires below the mat applicator. Additionally, the field embodied appropriately for its application is not disturbed by any other metal surfaces (metal floor, steel reinforcements). 
     Specifically,  FIG. 4  shows a coil system  20  with connectors  21  and  22 , which can be constructed in a simple fashion in one plane, for example embedded in a mat. In a second plane, arranged electrically isolated above the plane of the coil system  20 , an electrode  30  is arranged, which can be embodied as a closed surface or covering an area in form of individual conductive tapes. The power source  51  controlling the magnetic field feeds the controlling current to the connectors  21  and  22 . The voltage source  60  controlling the electric field creates a controlled potential between the electrode  30  and the coil system  20 . 
       FIG. 5  shows a special embodiment of the device for creating an electric field combined with a magnetic field, with the coil system being embodied such that a field distribution can develop adjusted to the physiology of the creature, representing either a human or an animal. 
     In this embodiment, the freedom for designing the coils that create the magnetic field is shown in an embodiment of the applicator according to  FIG. 4 .  FIG. 5  shows the coil system between the connector  21  and  22  comprising partial coils  201  and  202  as well as  203 . Furthermore, an electrode  30  is shown for the electric field. 
     The arrangement of the coils  201  and  202  is designed such that the current flows in the opposite direction. This way, the magnetic field is concentrated in the center, as discernible from the diagram of the distribution of the field strength in  FIG. 8 , section A-A. The arrangement of the coil  203  has been selected such that the embodiment of the magnetic field, strong over the lateral coil conductors, is optimally effective below the extremities, as shown in the diagram of the distribution of the field strength in  FIG. 8 , section B-B. The effect of the electrode is shown in  FIG. 7 , section C-C, as a diagram of field strengths. 
     The distribution of the electric field between the upper and the lower coil is discernible from  FIG. 6  in an arrangement according to  FIG. 3 . The flux lines can form, for example, between the positive potential of the coil  20  and a respective negative potential of the coil  30 . The symmetric embodiment upward and downward is discernible. 
       FIG. 7  shows the flux lines of an electric field, which develops, for example, between a positive electrode and the respective negative coil system. The lines each connect the positive, light side with the negative, dark side of the potential. 
       FIG. 8  shows the progression of the magnetic flux density over the coil arrangement adjusted to the given physiological conditions, with the diagram of the continuous line representing the progression in the area of section B-B (see  FIG. 5 ) and the dot-dash line the progression in the area of the section A-A (see  FIG. 5 ). The concentration of the field strength on the central area is discernible in section A-A, which is arranged preferably in the area of the spine, and the distribution of the field strength maximums at two sides such that this arrangement is preferred for the extremities. 
       FIG. 9  shows an embodiment of the device to create an electric field combined with a magnetic field similar to the embodiment according to  FIG. 5 , with the coils  201 ,  202 , and  203  only comprise a flat, level current loop. These level, parallel current paths can for example be integrated in a mat applicator, by conductive tape being implemented by way of electrically conducting yarn in form of warp and/or weft threads. Here, the conductive tapes are connected at one part such that a coil system develops adjusted to the given physiological conditions, with each of the coils of the system comprising only a single electric loop. 
     The current for creating the magnetic field is introduced through the power source I into the connector b. After the current has flown through the coils  202  and  201 , it is guided in coil  203  into the lower area and then via the connector c back to the power source. Using the voltage source U, an electric field is created between the electrode  30  and the coil system  201 ,  202 ,  203  by connecting the voltage via the connector a to the electrode  30  and via the connector c to the coil system. 
     In order to achieve a simple embodiment of the connection cable and to ensure an interfering influence of the environment being as little as possible, the connection cable is embodied with the conductors a, b, and c such that the electrically conductive wires a and b are twisted and the conductor c is pulled over the wires a and b as a shield. The arrangement of the coils occurs preferably such that the coils  201  and  202  become effective in the area of the spine of a human being or, if applicable, a vertebrate, and the coil  203  reaches its effectiveness in the area of the extremities, particularly the legs. In order to provide an optimal arrangement, here the distance between the upper and the lower coils can be designed in a variable fashion. 
     The distance at the longitudinal power path in the coil  203  is to be adjusted to the legs such that the maximums discernible in  FIG. 8  section B-B can optimally stimulate the magnetic flux density to the nerve tract as well as the peripheral blood vessels in the extremities. 
       FIG. 10  shows a simple device to check the functionality of the device for crating a combined electric and magnetic field with frequencies selected for the intended effect. 
     This device includes a coil  100 , together with the condenser  200  forming a resonance circle, adjusted to the characteristic frequency of the signal mixture of the i IIS —signal, e.g., 1000 Hz, and thus not registering 50 Hz—interference signals and other ones. The detector  300 , in the simplest case a diode, creates a control signal from the alternating voltage induced by the stimulus signal in an oscillating circuit, which is enhanced by the amplifier  400 , if applicable. The control signal is indicated by an indicator  500 , which in the simplest case may be a light emitting diode, however, it may also have several display states. 
     Following the same algorithm according to  FIG. 10 , a generalized device is realized according to the invention such that in addition to the device for checking the functionality of the device for creating a combined electric and magnetic field with the frequencies used for the desired effect additionally and simultaneously, via a separate system of coil/resonance circuit, the detection of 50 and/or 60 Hz interference signals is possible. 
       FIG. 11  shows that a reversal of the polarity of measures performed generally leads to a reduction of the quality of arterial blood flow as well as a worsening of the elasticity of the blood vessels (=increase of fiber stretching) in this application program. This exemplary embodiment confirms the dependency of the peripheral circulatory parameters in an E-field between the area near the head and the periphery. 
     In  FIG. 12  an oscillation period of the low-frequency sympathetic (a) as well as the parasympathetic (b) control frequency is shown as the basic oscillation of an appropriate stimulation program. The sympathetic (0.1 Hz=10 s oscillation period) and/or parasympathetic (0.25 Hz=4 s oscillation period) basic oscillations are interfered by appropriately higher-frequency oscillations, as discernible from  FIGS. 13  as well as  15  and  17 . 
     The IIS-function i IIS (t) according to  FIG. 13  interferes with the stimulation programs, especially the control frequencies 0.1 and 0.25 Hz as well as respective EEG-frequencies and the frequency 100 Hz, in order to dissolve primarily any (pathological) erythrocytic aggregation occurring and to achieve improved blood flow characteristics. These results can be deduced from measurements of capillary flow and microscopic blood dark area imaging. 
     It is discernible from  FIG. 14  how the erythrocytes separate under a stimulation with the IIS-function i IIS (t) according to  FIG. 13 , with obviously pathologic erythrocytic aggregation had existed prior to the stimulation. It has been learned according to the invention, in a stimulation first only to allow such an ISS signal to act for approximately 4 minutes, and subsequently to activate the stimulation application program (see  FIGS. 15 through 17 ). 
     While in  FIG. 15  for the stimulation program “Relax” the frequency of 2 Hz shows a typical EEG—delta frequency and in such delta frequencies highly significant changes of insomnia appear, there are also highly significant results, among other things, for immuno-biologic reactions, edema inhibition, sensitivity to weather, improvement of concentration, general increase in performance with 10 Hz-fields (also see the stimulation programs “Vitality” and “Performance” according to  FIGS. 16 and 17 .