Abstract:
A composition for providing temporary relief of sinus pain and nasal congestion uses natural products. The composition is preferably administered nasally.

Description:
PRIORITY  
       [0001]     This application claims the benefit of Patent provisional application Ser. No.: 60/500,354, filed Sep. 5, 2003 by the present inventors. 
     
    
     BACKGROUND OF THE INVENTION  
       [0002]     1. Field of Invention  
         [0003]     This invention relates to methods and compositions for reducing and alleviating respiratory problems. Particularly, this invention relates to methods and compositions for providing a temporary relief of sinus pain and nasal congestion. More particularly, this invention relates to the composition comprising an extract, which provides a temporary relief of sinus pain and nasal congestion. The composition of this invention may comprise a pharmaceutically acceptable carrier suitable for the chosen method and form of administration. In these embodiments, the composition may comprise a suitable carrier, and other ingredients such as flavors, stabilizers, lubricants, and additional natural or artificial sweeteners.  
         [0004]     2. General Background  
         [0005]     In the United States, it is estimated that a large percent of the population is afflicted with sinus pain and nasal congestion problems of sufficient severity to disturb the regular life of the person. Whatever the cause, the sinus pain and nasal congestion related problems produced are highly undesirable.  
         [0006]     In the past, therapy for eliminating or reducing sinus pain and nasal congestion has included the administration of decongestants and antihistamines, which generally have been ineffective. Such medications have exhibited, at best, limited success for reducing drainage due to colds, allergies and the like.  
         [0007]     The costs of treating sinus pain and nasal congestion with over-the-counter medications in the United States is estimated at an annual cost of over 1.5 billion dollars. The direct costs of treatment in outpatient clinics is estimated at almost four billion dollars, Indirect costs, based on the amount of loss in wages because of restricted activity are substantially higher. Accordingly, it is desirable to provide a simple, easy to use, relatively inexpensive, and effective procedure for substantially reducing or eliminating sinus pain and nasal congestion.  
         [0008]     Accordingly, it is desirable to provide a simple, easy to use, relatively inexpensive, and effective composition and procedure for substantially reducing or eliminating sinus pain and nasal congestion.  
       SUMMARY OF THE INVENTION  
       [0009]     It is an object of this invention to provide a composition for reducing sinus pain and nasal congestion. It is an additional object of this invention to provide an improved natural remedy for reducing sinus pain and nasal congestion.  
         [0010]     It is another object of this invention to provide an improved composition utilizing plant products for reducing sinus pain and nasal congestion.  
         [0011]     In accordance with a preferred embodiment of this invention, a decongestant composition, which includes a set of active components, comprising  Natrum muriaticum, Natrum muriaticum , Camphora, Mentholum and Eucalyptol. In a more preferred embodiment of this invention, the total active components is about 28% by weight or volume of said decongestant preparation. In a more preferred embodiment of this invention, the active components are about: 
    17.23%  Natrum muriaticum       3.78% Camphora     3.78% Mentholum     3.78% Eucalyptol 
 
 by weight or volume of said decongestant preparation. 
 
 In a more preferred embodiment of this invention, the decongestant composition may contain one or more, additional, components. In a more preferred embodiment of this invention, the decongestant composition contains as additional components at least one member selected from the group consisting of Natural Sweet Birch Oil, Benzoin Resin, Thymol, Natural Pine Oil, Cinnamon Oil, Spearmint Oil, Sodium Bicarbonate, and Water. In a more preferred embodiment of this invention, the components are present in an amount of about: 
        0.002212% Natural Sweet Birch Oil     0.001106% Benzoin Resin     0.001841% Thymol     0.0005687% Natural Pine Oil     0.0003782% Cinnamon Oil     0.0032999% Spearmint Oil     0.001116% Sodium Bicarbonate     71.41% Water 
 
 by weight or volume of said decongestant preparation 
   
       
 
         [0027]     In accordance with a preferred embodiment of this invention, a method of treating the occurrence of sinus pain and/or nasal congestion, comprising the step of:  
         [heading-0028]     administering to the subject a pharmaceutically effective amount of a composition comprising:  
         [none]    
       
         
           Natrum muriaticum  
         
          Camphora,  
          Mentholum  
          Eucalyptol  
          Natural Sweet Birch Oil  
          Benzoin Resin  
          Thymol  
          Natural Pine Oil  
          Cinnamon Oil  
          Spearmint Oil  
          Sodium Bicarbonate  
          Water 
 
 wherein the subject is a mammal, for example, wherein the subject is a human. 
 
       
     
         [0042]     In accordance with a preferred embodiment of this invention, a method of inhibiting the occurrence of sinus pain and/or nasal congestion, comprising the step of: administering to the subject a pharmaceutically effective amount of a composition comprising: 
     Natrum muriaticum       Camphora,     Mentholum     Eucalyptol     Natural Sweet Birch Oil     Benzoin Resin     Thymol     Natural Pine Oil     Cinnamon Oil     Spearmint Oil     Sodium Bicarbonate     Water 
 
 wherein subject is a mammal, wherein the subject is a human. 
   
 
         [0056]     In accordance with a preferred embodiment of this invention, a method is disclosed for reducing or alleviating respiratory problems comprising the step of: administering to the subject a pharmaceutically effective amount of a composition comprising: 
     Natrum muriaticum       Camphora,     Mentholum     Eucalyptol     Natural Sweet Birch Oil     Benzoin Resin     Thymol     Natural Pine Oil     Cinnamon Oil     Spearmint Oil     Sodium Bicarbonate     Water 
 
 wherein subject is a mammal, for example, wherein the subject is a human, wherein the respiratory problem is a sinus pain or a nasal congestion. 
   
 
         [0070]     In accordance with a preferred embodiment of this invention, a composition for reducing sinus pain and nasal congestion and alleviating respiratory problems is comprised of compounds of Sinusol that are listed in Table (1).  
         [0071]     The composition of this invention is preferably administered nasally. The composition may be administered, but not limited to, as extract, as liquid extract in liquid, as capsules or as tablets, with doses administered according to the weight of the user. 
     
    
     DETAILED DESCRIPTION  
       [0072]     It is an object of this invention to provide a composition for reducing sinus pain and nasal congestion. It is an additional object of this invention to provide an improved natural remedy for reducing sinus pain and nasal congestion.  
         [0073]     It is another object of this invention to provide an improved composition utilizing plant products for reducing sinus pain and nasal congestion.  
         [0074]     In accordance with a preferred embodiment of this invention, a decongestant composition comprising a set of active components comprising  Natrum muriaticum, Natrum muriaticum , Camphora, Mentholum and Eucalyptol. In a more preferred embodiment of this invention, the total active components is about 28% by weight or volume of said decongestant preparation. In a more preferred embodiment of this invention, the active components are about: 
    17.23%  Natrum muriaticum       3.78% Camphora     3.78% Mentholum     3.78% Eucalyptol 
 
 by weight or volume of said decongestant preparation. 
   
 
         [0080]     In a more preferred embodiment of this invention, the decongestant composition contains as additional one or more components. In a more preferred embodiment of this invention, the decongestant composition contains as additional components at least one member selected from the group consisting of Natural Sweet Birch Oil, Benzoin Resin, Thymol, Natural Pine Oil, Cinnamon Oil, Spearmint Oil, Sodium Bicarbonate, and Water. In a more preferred embodiment of this invention, the components are about: 
        0.002212% Natural Sweet Birch Oil     0.001106% Benzoin Resin     0.001841% Thymol     0.0005687% Natural Pine Oil     0.0003782% Cinnamon Oil     0.0032999% Spearmint Oil     0.001116% Sodium Bicarbonate     71.41% Water 
 
 by weight or volume of said decongestant preparation. 
       
 
         [0090]     In accordance with a preferred embodiment of this invention, a method of treating the occurrence of sinus pain and/or nasal congestion, comprising the step of:  
         [heading-0091]     administering to the subject a pharmaceutically effective amount of a composition comprising:  
         [none]    
       
         
           Natrum muriaticum  
         
          Camphora,  
          Mentholum  
          Eucalyptol  
          Natural Sweet Birch Oil  
          Benzoin Resin  
          Thymol  
          Natural Pine Oil  
          Cinnamon Oil  
          Spearmint Oil  
          Sodium Bicarbonate  
          Water 
 
 wherein subject is a mammal, for example, wherein the subject is human. 
 
       
     
         [0105]     In accordance with a preferred embodiment of this invention, a method of inhibiting the occurrence of sinus pain and/or nasal congestion, comprising the step of:  
         [heading-0106]     administering to the subject a pharmaceutically effective amount of a composition comprising:  
         [none]    
       
         
           Natrum muriaticum  
         
          Camphora,  
          Mentholum  
          Eucalyptol  
          Natural Sweet Birch Oil  
          Benzoin Resin  
          Thymol  
          Natural Pine Oil  
          Cinnamon Oil  
          Spearmint Oil  
          Sodium Bicarbonate  
          Water 
 
 wherein subject is a mammal, for example, wherein the subject is a human. 
 
       
     
         [0120]     In accordance with a preferred embodiment of this invention, a method is disclosed which is useful for reducing or alleviating respiratory problems comprising the step of:  
         [heading-0121]     administering to the subject a pharmaceutically effective amount of a composition comprising:  
         [none]    
       
         
           Natrum muriaticum  
         
          Camphora,  
          Mentholum  
          Eucalyptol  
          Natural Sweet Birch Oil  
          Benzoin Resin  
          Thymol  
          Natural Pine Oil  
          Cinnamon Oil  
          Spearmint Oil  
          Sodium Bicarbonate  
          Water 
 
 wherein the subject is a mammal, for example, wherein the subject is a human, and wherein the respiratory problem is a sinus pain or a nasal congestion. 
 
       
     
         [0135]     In accordance with a preferred embodiment of this invention, a composition for reducing sinus pain and nasal congestion and alleviating respiratory problems is comprised of compounds of Sinusol that are listed in Table (1).  
         [0136]     In accordance with a preferred embodiment of this invention, a composition for reducing sinus pain and nasal congestion comprising plant products and extracts was discovered (Table 1). The invention is not limited to various ranges of formulation as listed in Table (1). The products are preferably combined and are placed in a liquid base for nasal administration or administration in a spray or mist form.  
                                                 TABLE 1                       ORIGINAL       POTENTIAL   ml or g                                            Actives           Sodium   0.001723   g   Natrum muriaticum   17.23       Camphor   0.003782   g   Camphora 3X   3.78       Menthol   0.003782   g   Mentholum 3X   3.78       Eucalyptol   0.003782   g   Eucalyptol 3X   3.78                   Total Actives   28.58                   Inactives       Natural Sweet   0.002212   g   Natural Sweet Birch   0.002212       Birch           Oil       Benzoin Resin   0.001106   g   Benzoin Resin   0.001106       Thymol   0.001841   g   Thymol   0.001841       Natural Pine Oil   0.0005687       Natural Pine Oil   0.0005687       Natural   0.0003782       Cinnamon Oil   0.0003782       Spearmint Oil   0.0032999       Spearmint Oil   0.0032999       Alcohol   3.75   g   Ethanol   0       Sodium   0.001116   g   Sodium   0.001116       Bicarbonate           Bicarbonate       Balance Water   96.23   g   Water   71.41       Total   100   g       100                  
 
         [0137]     To make it easy for the chemist to prepare the formulation, the following is the same formula calculated for 1 gallon of bulk product:  
                                                 TABLE 2                       ORIGINAL       POTENTIAL   ml or g                                            Actives           Sodium   0.06521555       Natrum muriaticum   652.16       Camphor   0.1431487       Camphora 3X   143.15       Menthol   0.1431487       Mentholum 3X   143.15       Eucalyptol   0.1431487       Eucalyptol 3X   143.15                   Total Actives   1,081.60                   Inactives       Natural Sweet   0.0837242       Natural Sweet Birch   0.0837242       Benzoin Resin   0.0418621       Benzoin Resin   0.0418621       Thymol   0.06968185       Thymol   0.0696818       Natural   0.0215253       Natural Pine Oil   0.0215252       Pine Oil       Natural   0.01431487       Cinnamon Oil   0.0143148       Spearmint Oil   0.12490122       Spearmint Oil   0.1249012       Alcohol   141.9375   ml   Ethanol   0       Sodium   0.04224060       Sodium   0.042241       Balance Water   3,641.17   g   Water   71.41       Total   3785   ml       2,703.00                  
 
         [0138]     The total of the 4 active ingredients (1,081.6 ml) are prepared using 261.98 ml of ethanol and 819.12 of water.  
                                                           TABLE 3                           The following is the formula which would       be needed for this bulk quantity:            ORIGINAL       POTENTIAL   ml or g                                Actives               Sodium   3.58685525       Natrum   35,868.552                       muriaticum       Camphor   7.8731785       Camphora 3X   7,873.1785       Menthol   7.8731785       Mentholum 3X   7,873.1785       Eucalyptol   7.8731785       Eucalyptol 3X   7,873.1785                   Total Actives   59,488.88                   Inactives       Natural Sweet   4.604831   ml   Natural   4.604831                   Sweet Birch       Benzoin Resin   2.3024155       Benzoin Resin   2.3024155       Thymol   3.83250175       Thymol   3.8325017       Natural Pine Oil   1.18389123       Natural   1.1838912                   Pine Oil       Natural   0.78731785       Cinnamon Oil   0.7873178       Spearmint Oil   6.86956683       Spearmint Oil   6.8695668       Alcohol   7,806.5625       Ethanol   0       Sodium   2.323233   g   Sodium   2.323233   g       Balance Water   200,264.33       Water   148,665   ml       Total   208,175   ml       208,175   ml                  
 
 The total of the 4 active ingredients (59,488.88 ml) are prepared using 14,409.1 ml of ethanol and 45,051.78 ml of water. 
 
         [0140]     Although various ranges of formulation have been described above, various changes and modifications may be made by those skilled in the art for performing substantially the same function, in substantially the same way, to achieve substantially the same result, without departing from the true scope of the invention as defined in the appended claims.  
         [heading-0141]     Drawing Descriptions: No drawing description