Cage wrote his master’s thesis on the effects of indole hallucinogens on serontonergic and dopaminergic receptors. The eary indole hallucinogens like LSD and DMT had long since been thought to inhibit production of the neuroregulator serotonin, not surprising since their chemical structures were remarkably similar. His work showed that hallucinogens of this family also effect the dopamine-producing system and that many of the reported effects of these drugs resulted from interactions between these neuroregulators. It was not, he had to admit, particularly innovative or brilliant work; the foundations had been laid long ago. But by then he had grown tremendously bored with being a student. The work reflected it.