Chapter 3 is rather technical. Given Dr. Hotton’s light and popular style, it makes splendid reading. Dr. Hotton attempts to reconstruct Berenbaum’s crude attempts to rectify the situation through gross manipulation of the AIDS RNA transcriptase. What Berenbaum sought, of course, was a way to shut-off and start-up the transcriptase carrier, so that the internal drug factory could be activated at will. Berenbaum’s custom transcriptase was designed to react to a simple user-induced trigger—probably D,1,2,5-phospholytic gluteinase, a fractionated component of "Dr. Brown’s Celery Soda," as Hotton suggests. This harmless beverage was a favorite quaff of gene-hacker circles.