Three semesters later it all went wrong. By then he was poking megamphetamines in massive doses, sometimes over eighty milligrams. The initial rush felt like a whole-body orgasm; he did not feel like studying much afterward. His advisor told him to switch out of the program after he took a "C" in genetic chemistry. He was burning up brain cells and losing weight; he had already lost his direction. He knew he had to get clean and start over again.