lovingscience/chembl-v37-raw-activities huggingface dataset:
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Structural maintenance of chromosomes protein 2 (SINGLE PROTEIN), Homo sapiens
UniProt: O95347
Assay: Binding affinity to human SMC2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 5620.1 nM (pChEMBL 5.25)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Structural maintenance of chromosomes protein 3 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UQE7
Assay: Binding affinity to human SMC3 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 43.39 nM (pChEMBL 7.360000133514404)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Structural maintenance of chromosomes protein 3 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UQE7
Assay: Binding affinity to human SMC3 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 43.39 nM (pChEMBL 7.360000133514404)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Structural maintenance of chromosomes protein 4 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9NTJ3
Assay: Binding affinity to human SMC4 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 7321.27 nM (pChEMBL 5.130000114440918)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Structural maintenance of chromosomes protein 4 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9NTJ3
Assay: Binding affinity to human SMC4 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 7321.27 nM (pChEMBL 5.130000114440918)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Synaptosomal-associated protein 23 (SINGLE PROTEIN), Homo sapiens
UniProt: O00161
Assay: Binding affinity to human SNAP23 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 10414.94 nM (pChEMBL 4.980000019073486)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Synaptosomal-associated protein 23 (SINGLE PROTEIN), Homo sapiens
UniProt: O00161
Assay: Binding affinity to human SNAP23 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 11224.5 nM (pChEMBL 4.949999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Staphylococcal nuclease domain-containing protein 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q7KZF4
Assay: Binding affinity to human SND1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 23596.07 nM (pChEMBL 4.630000114440918)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Staphylococcal nuclease domain-containing protein 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q7KZF4
Assay: Binding affinity to human SND1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 23596.07 nM (pChEMBL 4.630000114440918)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: U5 small nuclear ribonucleoprotein 200 kDa helicase (SINGLE PROTEIN), Homo sapiens
UniProt: O75643
Assay: Binding affinity to human SNRNP200 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 6151.8 nM (pChEMBL 5.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: U5 small nuclear ribonucleoprotein 200 kDa helicase (SINGLE PROTEIN), Homo sapiens
UniProt: O75643
Assay: Binding affinity to human SNRNP200 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 6151.8 nM (pChEMBL 5.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Small nuclear ribonucleoprotein Sm D2 (SINGLE PROTEIN), Homo sapiens
UniProt: P62316
Assay: Binding affinity to human SNRPD2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 42679.95 nM (pChEMBL 4.369999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Small nuclear ribonucleoprotein Sm D2 (SINGLE PROTEIN), Homo sapiens
UniProt: P62316
Assay: Binding affinity to human SNRPD2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 42679.95 nM (pChEMBL 4.369999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Sterol O-acyltransferase 1 (SINGLE PROTEIN), Homo sapiens
UniProt: P35610
Assay: Binding affinity to human SOAT1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 224239.39 nM (pChEMBL 3.6500000953674316)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Microtubule cross-linking factor 3 (SINGLE PROTEIN), Homo sapiens
UniProt: Q5TF21
Assay: Binding affinity to human SOGA3 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 11879.31 nM (pChEMBL 4.920000076293945)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Microtubule cross-linking factor 3 (SINGLE PROTEIN), Homo sapiens
UniProt: Q5TF21
Assay: Binding affinity to human SOGA3 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 11879.31 nM (pChEMBL 4.920000076293945)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal peptidase complex subunit 2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q15005
Assay: Binding affinity to human SPCS2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 916.14 nM (pChEMBL 6.039999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal peptidase complex subunit 2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q15005
Assay: Binding affinity to human SPCS2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 916.14 nM (pChEMBL 6.039999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Spectrin alpha chain, non-erythrocytic 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13813
Assay: Binding affinity to human SPTAN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 79.95 nM (pChEMBL 7.099999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Spectrin alpha chain, non-erythrocytic 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13813
Assay: Binding affinity to human SPTAN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 79.95 nM (pChEMBL 7.099999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Spectrin beta chain, non-erythrocytic 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q01082
Assay: Binding affinity to human SPTBN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1608.83 nM (pChEMBL 5.789999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Spectrin beta chain, non-erythrocytic 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q01082
Assay: Binding affinity to human SPTBN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 1608.83 nM (pChEMBL 5.789999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine palmitoyltransferase 1 (SINGLE PROTEIN), Homo sapiens
UniProt: O15269
Assay: Binding affinity to human SPTLC1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 613.22 nM (pChEMBL 6.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine palmitoyltransferase 1 (SINGLE PROTEIN), Homo sapiens
UniProt: O15269
Assay: Binding affinity to human SPTLC1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 613.22 nM (pChEMBL 6.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Proto-oncogene tyrosine-protein kinase Src (SINGLE PROTEIN), Homo sapiens
UniProt: P12931
Assay: Binding affinity to human SRC incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1412.54 nM (pChEMBL 5.849999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Proto-oncogene tyrosine-protein kinase Src (SINGLE PROTEIN), Homo sapiens
UniProt: P12931
Assay: Binding affinity to human SRC incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1398.51 nM (pChEMBL 5.849999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Proto-oncogene tyrosine-protein kinase Src (SINGLE PROTEIN), Homo sapiens
UniProt: P12931
Assay: Binding affinity to human SRC incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 3601.99 nM (pChEMBL 5.440000057220459)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle 14 kDa protein (SINGLE PROTEIN), Homo sapiens
UniProt: P37108
Assay: Binding affinity to human SRP14 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 20262.69 nM (pChEMBL 4.690000057220459)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle 14 kDa protein (SINGLE PROTEIN), Homo sapiens
UniProt: P37108
Assay: Binding affinity to human SRP14 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 20262.69 nM (pChEMBL 4.690000057220459)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle subunit SRP68 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UHB9
Assay: Binding affinity to human SRP68 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 4087.32 nM (pChEMBL 5.389999866485596)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle subunit SRP68 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UHB9
Assay: Binding affinity to human SRP68 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 4087.32 nM (pChEMBL 5.389999866485596)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle subunit SRP72 (SINGLE PROTEIN), Homo sapiens
UniProt: O76094
Assay: Binding affinity to human SRP72 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 7.631 nM (pChEMBL 8.119999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle subunit SRP72 (SINGLE PROTEIN), Homo sapiens
UniProt: O76094
Assay: Binding affinity to human SRP72 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 7.631 nM (pChEMBL 8.119999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle 9 kDa protein (SINGLE PROTEIN), Homo sapiens
UniProt: P49458
Assay: Binding affinity to human SRP9 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 5322.83 nM (pChEMBL 5.269999980926514)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Signal recognition particle 9 kDa protein (SINGLE PROTEIN), Homo sapiens
UniProt: P49458
Assay: Binding affinity to human SRP9 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 5322.83 nM (pChEMBL 5.269999980926514)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serrate RNA effector molecule homolog (SINGLE PROTEIN), Homo sapiens
UniProt: Q9BXP5
Assay: Binding affinity to human SRRT incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1130.82 nM (pChEMBL 5.949999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serrate RNA effector molecule homolog (SINGLE PROTEIN), Homo sapiens
UniProt: Q9BXP5
Assay: Binding affinity to human SRRT incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 1130.82 nM (pChEMBL 5.949999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q07955
Assay: Binding affinity to human SRSF1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 9124.46 nM (pChEMBL 5.039999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q07955
Assay: Binding affinity to human SRSF1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 9124.46 nM (pChEMBL 5.039999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q01130
Assay: Binding affinity to human SRSF2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 29382 nM (pChEMBL 4.53000020980835)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q01130
Assay: Binding affinity to human SRSF2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 29382 nM (pChEMBL 4.53000020980835)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 3 (SINGLE PROTEIN), Homo sapiens
UniProt: P84103
Assay: Binding affinity to human SRSF3 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1061.97 nM (pChEMBL 5.96999979019165)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 3 (SINGLE PROTEIN), Homo sapiens
UniProt: P84103
Assay: Binding affinity to human SRSF3 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 1061.97 nM (pChEMBL 5.96999979019165)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 6 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13247
Assay: Binding affinity to human SRSF6 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 5983.26 nM (pChEMBL 5.21999979019165)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 6 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13247
Assay: Binding affinity to human SRSF6 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 5983.26 nM (pChEMBL 5.21999979019165)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 7 (SINGLE PROTEIN), Homo sapiens
UniProt: Q16629
Assay: Binding affinity to human SRSF7 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 7.578 nM (pChEMBL 8.119999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/arginine-rich splicing factor 7 (SINGLE PROTEIN), Homo sapiens
UniProt: Q16629
Assay: Binding affinity to human SRSF7 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 7.578 nM (pChEMBL 8.119999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Lupus La protein (SINGLE PROTEIN), Homo sapiens
UniProt: P05455
Assay: Binding affinity to human SSB incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1939.86 nM (pChEMBL 5.710000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Lupus La protein (SINGLE PROTEIN), Homo sapiens
UniProt: P05455
Assay: Binding affinity to human SSB incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 1939.86 nM (pChEMBL 5.710000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Single-stranded DNA-binding protein, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: Q04837
Assay: Binding affinity to human SSBP1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 6.21 nM (pChEMBL 8.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Single-stranded DNA-binding protein, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: Q04837
Assay: Binding affinity to human SSBP1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 6.21 nM (pChEMBL 8.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Translocon-associated protein subunit alpha (SINGLE PROTEIN), Homo sapiens
UniProt: P43307
Assay: Binding affinity to human SSR1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 12243 nM (pChEMBL 4.909999847412109)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Translocon-associated protein subunit alpha (SINGLE PROTEIN), Homo sapiens
UniProt: P43307
Assay: Binding affinity to human SSR1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 12243 nM (pChEMBL 4.909999847412109)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Translocon-associated protein subunit gamma (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UNL2
Assay: Binding affinity to human SSR3 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 12683.61 nM (pChEMBL 4.900000095367432)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Translocon-associated protein subunit gamma (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UNL2
Assay: Binding affinity to human SSR3 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 12683.61 nM (pChEMBL 4.900000095367432)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Translocon-associated protein subunit delta (SINGLE PROTEIN), Homo sapiens
UniProt: P51571
Assay: Binding affinity to human SSR4 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 216684.44 nM (pChEMBL 3.6600000858306885)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: FACT complex subunit SSRP1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q08945
Assay: Binding affinity to human SSRP1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 2.228 nM (pChEMBL 8.649999618530273)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: FACT complex subunit SSRP1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q08945
Assay: Binding affinity to human SSRP1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 2.228 nM (pChEMBL 8.649999618530273)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Double-stranded RNA-binding protein Staufen homolog 1 (SINGLE PROTEIN), Homo sapiens
UniProt: O95793
Assay: Binding affinity to human STAU1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 2267.04 nM (pChEMBL 5.639999866485596)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Double-stranded RNA-binding protein Staufen homolog 1 (SINGLE PROTEIN), Homo sapiens
UniProt: O95793
Assay: Binding affinity to human STAU1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 2267.04 nM (pChEMBL 5.639999866485596)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stress-induced-phosphoprotein 1 (SINGLE PROTEIN), Homo sapiens
UniProt: P31948
Assay: Binding affinity to human STIP1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 3829.34 nM (pChEMBL 5.420000076293945)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stress-induced-phosphoprotein 1 (SINGLE PROTEIN), Homo sapiens
UniProt: P31948
Assay: Binding affinity to human STIP1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 3829.34 nM (pChEMBL 5.420000076293945)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 10 (SINGLE PROTEIN), Homo sapiens
UniProt: O94804
Assay: Binding affinity to human STK10 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 2579.09 nM (pChEMBL 5.590000152587891)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 10 (SINGLE PROTEIN), Homo sapiens
UniProt: O94804
Assay: Binding affinity to human STK10 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 2817.23 nM (pChEMBL 5.550000190734863)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase STK11 (SINGLE PROTEIN), Homo sapiens
UniProt: Q15831
Assay: Binding affinity to human STK11 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 2012.99 nM (pChEMBL 5.699999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase STK11 (SINGLE PROTEIN), Homo sapiens
UniProt: Q15831
Assay: Binding affinity to human STK11 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 2386.45 nM (pChEMBL 5.619999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 16 (SINGLE PROTEIN), Homo sapiens
UniProt: O75716
Assay: Binding affinity to human STK16 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 93.93 nM (pChEMBL 7.03000020980835)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 16 (SINGLE PROTEIN), Homo sapiens
UniProt: O75716
Assay: Binding affinity to human STK16 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 130.45 nM (pChEMBL 6.880000114440918)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 26 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9P289
Assay: Binding affinity to human STK26 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 236.74 nM (pChEMBL 6.630000114440918)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 26 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9P289
Assay: Binding affinity to human STK26 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 269.54 nM (pChEMBL 6.570000171661377)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 3 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13188
Assay: Binding affinity to human STK3 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 10849.43 nM (pChEMBL 4.960000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 3 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13188
Assay: Binding affinity to human STK3 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 14196.3 nM (pChEMBL 4.849999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 4 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13043
Assay: Binding affinity to human STK4 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 2079.5 nM (pChEMBL 5.679999828338623)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine/threonine-protein kinase 4 (SINGLE PROTEIN), Homo sapiens
UniProt: Q13043
Assay: Binding affinity to human STK4 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 2727.14 nM (pChEMBL 5.559999942779541)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stathmin (SINGLE PROTEIN), Homo sapiens
UniProt: P16949
Assay: Binding affinity to human STMN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 12431.99 nM (pChEMBL 4.909999847412109)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stathmin (SINGLE PROTEIN), Homo sapiens
UniProt: P16949
Assay: Binding affinity to human STMN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 12431.99 nM (pChEMBL 4.909999847412109)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stathmin-2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q93045
Assay: Binding affinity to human STMN2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 4.393 nM (pChEMBL 8.359999656677246)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stathmin-2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q93045
Assay: Binding affinity to human STMN2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 4.393 nM (pChEMBL 8.359999656677246)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stomatin-like protein 2, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UJZ1
Assay: Binding affinity to human STOML2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 19.88 nM (pChEMBL 7.699999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Stomatin-like protein 2, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UJZ1
Assay: Binding affinity to human STOML2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 19.88 nM (pChEMBL 7.699999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine-threonine kinase receptor-associated protein (SINGLE PROTEIN), Homo sapiens
UniProt: Q9Y3F4
Assay: Binding affinity to human STRAP incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 231.17 nM (pChEMBL 6.639999866485596)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Serine-threonine kinase receptor-associated protein (SINGLE PROTEIN), Homo sapiens
UniProt: Q9Y3F4
Assay: Binding affinity to human STRAP incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 231.17 nM (pChEMBL 6.639999866485596)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (SINGLE PROTEIN), Homo sapiens
UniProt: P46977
Assay: Binding affinity to human STT3A incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 1123.85 nM (pChEMBL 5.949999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (SINGLE PROTEIN), Homo sapiens
UniProt: P46977
Assay: Binding affinity to human STT3A incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 1123.85 nM (pChEMBL 5.949999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (SINGLE PROTEIN), Homo sapiens
UniProt: Q8TCJ2
Assay: Binding affinity to human STT3B incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 625.66 nM (pChEMBL 6.199999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (SINGLE PROTEIN), Homo sapiens
UniProt: Q8TCJ2
Assay: Binding affinity to human STT3B incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 625.66 nM (pChEMBL 6.199999809265137)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Activated RNA polymerase II transcriptional coactivator p15 (SINGLE PROTEIN), Homo sapiens
UniProt: P53999
Assay: Binding affinity to human SUB1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 1094052.46 nM (pChEMBL 2.9600000381469727)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: Q9P2R7
Assay: Binding affinity to human SUCLA2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 5028.27 nM (pChEMBL 5.300000190734863)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: Q9P2R7
Assay: Binding affinity to human SUCLA2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 5028.27 nM (pChEMBL 5.300000190734863)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: P53597
Assay: Binding affinity to human SUCLG1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 56.31 nM (pChEMBL 7.25)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (SINGLE PROTEIN), Homo sapiens
UniProt: P53597
Assay: Binding affinity to human SUCLG1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 56.31 nM (pChEMBL 7.25)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Protein SGT1 homolog (SINGLE PROTEIN), Homo sapiens
UniProt: Q9Y2Z0
Assay: Binding affinity to human SUGT1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 17238.38 nM (pChEMBL 4.760000228881836)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Protein SGT1 homolog (SINGLE PROTEIN), Homo sapiens
UniProt: Q9Y2Z0
Assay: Binding affinity to human SUGT1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 17238.38 nM (pChEMBL 4.760000228881836)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: SUN domain-containing protein 2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UH99
Assay: Binding affinity to human SUN2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 13519.63 nM (pChEMBL 4.869999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: SUN domain-containing protein 2 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9UH99
Assay: Binding affinity to human SUN2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 13519.63 nM (pChEMBL 4.869999885559082)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: FACT complex subunit SPT16 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9Y5B9
Assay: Binding affinity to human SUPT16H incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 4.602 nM (pChEMBL 8.34000015258789)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: FACT complex subunit SPT16 (SINGLE PROTEIN), Homo sapiens
UniProt: Q9Y5B9
Assay: Binding affinity to human SUPT16H incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 4.602 nM (pChEMBL 8.34000015258789)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Surfeit locus protein 4 (SINGLE PROTEIN), Homo sapiens
UniProt: O15260
Assay: Binding affinity to human SURF4 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 17.04 nM (pChEMBL 7.769999980926514)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Surfeit locus protein 4 (SINGLE PROTEIN), Homo sapiens
UniProt: O15260
Assay: Binding affinity to human SURF4 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 17.04 nM (pChEMBL 7.769999980926514)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Tyrosine-protein kinase SYK (SINGLE PROTEIN), Homo sapiens
UniProt: P43405
Assay: Binding affinity to human SYK incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 3224.84 nM (pChEMBL 5.489999771118164)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Tyrosine-protein kinase SYK (SINGLE PROTEIN), Homo sapiens
UniProt: P43405
Assay: Binding affinity to human SYK incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 3845.87 nM (pChEMBL 5.420000076293945)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Heterogeneous nuclear ribonucleoprotein Q (SINGLE PROTEIN), Homo sapiens
UniProt: O60506
Assay: Binding affinity to human SYNCRIP incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 22.5 nM (pChEMBL 7.650000095367432)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Heterogeneous nuclear ribonucleoprotein Q (SINGLE PROTEIN), Homo sapiens
UniProt: O60506
Assay: Binding affinity to human SYNCRIP incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 22.5 nM (pChEMBL 7.650000095367432)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Synaptogyrin-2 (SINGLE PROTEIN), Homo sapiens
UniProt: O43760
Assay: Binding affinity to human SYNGR2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 44410.01 nM (pChEMBL 4.349999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Synaptogyrin-2 (SINGLE PROTEIN), Homo sapiens
UniProt: O43760
Assay: Binding affinity to human SYNGR2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 44410.01 nM (pChEMBL 4.349999904632568)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Synaptophysin-like protein 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q16563
Assay: Binding affinity to human SYPL1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 6212.93 nM (pChEMBL 5.210000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Synaptophysin-like protein 1 (SINGLE PROTEIN), Homo sapiens
UniProt: Q16563
Assay: Binding affinity to human SYPL1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 6426.63 nM (pChEMBL 5.190000057220459)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: E3 ubiquitin-protein ligase synoviolin (SINGLE PROTEIN), Homo sapiens
UniProt: Q86TM6
Assay: Binding affinity to human SYVN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 162.1 nM (pChEMBL 6.789999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: E3 ubiquitin-protein ligase synoviolin (SINGLE PROTEIN), Homo sapiens
UniProt: Q86TM6
Assay: Binding affinity to human SYVN1 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 162.1 nM (pChEMBL 6.789999961853027)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Transgelin-2 (SINGLE PROTEIN), Homo sapiens
UniProt: P37802
Assay: Binding affinity to human TAGLN2 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 3153.32 nM (pChEMBL 5.5)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Transgelin-2 (SINGLE PROTEIN), Homo sapiens
UniProt: P37802
Assay: Binding affinity to human TAGLN2 incubated for 45 mins by Kinobead based pull down assay
Measurement: ED50 = 3153.32 nM (pChEMBL 5.5)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32
Compound (SMILES): Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
InChIKey: ZCCPLJOKGAACRT-UHFFFAOYSA-N
Target: Transaldolase (SINGLE PROTEIN), Homo sapiens
UniProt: P37837
Assay: Binding affinity to human TALDO1 incubated for 45 mins by Kinobead based pull down assay
Measurement: Kd = 34354.3 nM (pChEMBL 4.460000038146973)
Descriptors: MW 503.49, ALogP 5.75, HBA 7, HBD 2, PSA 97.62, QED 0.32