Clinical trial NCT05928351: Pain Neuroscience Education in Patients With Total Knee Arthroplasty
Official title: Investigation of the Efficacy of Neuroscience Pain Education in Patients With Total Knee Arthroplasty
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoarthritis, Knee
Keywords: pain neuroscience education
knee
osteoarthritis
Lead sponsor: Ahi Evran University Education and Research Hospital
Sponsor class: OTHER
First posted: 2023-07-03
Enrollment: 34
Sex: ALL
Minimum age (years): 40
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized
Primary purpose: TREATMENT

Brief summary: The aim of Pain Neuroscience Education (PNE) is to explain to patients the biological and physiological processes involved in a pain experience and, more importantly, defocus the issues associated with the anatomical structures. PNE provides compelling evidence in reducing pain, disability, pain catastrophization, and limited physical movement in musculoskeletal problems. Knee osteoarthritis (KOA) is a very common painful musculoskeletal problem, especially in people over 50 years old, and lead to decrease in knee range of motion. Despite costly arthroscopic surgeries and long-term physiotherapy treatments, poor outcomes are common. The lack of satisfactory results suggests that some practices should be revised. Although PNE could be useful as an intervention, to our knowledge, there is no randomized controlled trial in the literature investigating the effects of PNE in patients with a KOA. Therefore, we aimed to examine the effectiveness of PNE on clinical outcomes in patients with KOA.


Eligibility criteria: Inclusion Criteria:

* Having a body mass index between 19-40 kg/m2,
* Having had a unilateral TKA,
* Knee pain score to be 4 and above daily according to the visual analog scale,
* Ability to read, speak and understand Turkish.

Exclusion Criteria:

* Prosthesis disorders requiring re-surgery,
* Having visual, auditory and cognitive impairment,
* Secondary TKA such as rheumatoid arthritis,
* Acute pain,
* Pregnancy, drug and alcohol use,
* Having bilateral TKA,
* Not volunteering to participate in the study

Primary outcomes:
measure: Pain severity
timeFrame: Baseline
measure: Pain severity change is being assessed
timeFrame: 6 week
measure: Pain and Function
timeFrame: Baseline
measure: Pain and Function change are being assessed
timeFrame: 6 week
measure: Pain and Function
timeFrame: Baseline
measure: Pain and Function change are being assessed
timeFrame: 6 week
Secondary outcomes:
measure: Pain Catastrophizing
timeFrame: Baseline
measure: Pain Catastrophizing change is being assessed
timeFrame: 6 week
measure: Kinesiophobia
timeFrame: Baseline
measure: Kinesiophobia change is being assessed
timeFrame: 6 week
measure: Level of quality of life
timeFrame: Baseline
measure: Level of quality of life change is being assessed
timeFrame: 6 week
measure: Anxiety and Depression
timeFrame: Baseline
measure: Anxiety and Depression change is being assessed
timeFrame: 6 week
measure: Physical Function
timeFrame: Baseline
measure: Physical Function change is being assessed
timeFrame: 6 week
Other outcomes:
Locations:
city: Kırşehir
country: Turkey
facility: Ahi Evran University
state: Central
Study officials:
References:
citation: Louw A, Diener I, Butler DS, Puentedura EJ. The effect of neuroscience education on pain, disability, anxiety, and stress in chronic musculoskeletal pain. Arch Phys Med Rehabil. 2011 Dec;92(12):2041-56. doi: 10.1016/j.apmr.2011.07.198.
citation: Louw A PT, PhD, Zimney K PT, DPT, Reed J PT, DPT, Landers M PT, DPT, PhD, Puentedura EJ PT, DPT, PhD. Immediate preoperative outcomes of pain neuroscience education for patients undergoing total knee arthroplasty: A case series. Physiother Theory Pract. 2019 Jun;35(6):543-553. doi: 10.1080/09593985.2018.1455120. Epub 2018 Mar 28.