Clinical trial NCT03778905: The Correlation Between the Length of Stay in Post Acute Care(PAC) and General Improvements in Stroke Patients
Official title: The Correlation Between the Length of Stay in Post Acute Care(PAC) and General Improvements in Stroke Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Stroke
Lead sponsor: Chimei Medical Center
Sponsor class: OTHER
First posted: 2018-12-19
Enrollment: 305
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Stroke patient who meet up criteria of \>18 y/o, acute onset of stroke within 30 days and Modified Rankin Scale 2\~4 as well as complete post acute care(PAC) rehabilitative program.

Brief summary: Post-Acute Care(PAC) had been inaugurated in Taiwan for almost four years and current essays revealed positive effects upon general improvements in stroke patient after PAC training. During acute phase, a stroke patient would admit to internal medicine or surgical ward and transferred to rehabilitative ward for more intensive therapeutic programs, restoring muscle power and promoting activity of daily life(ADL) ability. Under relative stable condition, the patient would transfer to PAC institution or hospitals afterwards for continuing rehabilitative program if the patient is acknowledged to have rehabilitative potentials. However, there's still lacking of investigation upon whether the length of stay in PAC correlates to general improvements. Thus, stroke patients' functional ability, such as activities of daily living (ADL) function, swallowing ability and so on, as well as their corresponding scales were assessed on the first and last day during PAC hospitalization. Statistical analysis was conducted via SPSS ver21.0 to compare the relationship of improvements in functional ability and the length of stay in PAC. We're looking forward to the final results!

Detailed description: Functional ability in stroke patients are evaluated by following measurements. Activity of daily life (ADL) function was estimated through modified Rankin scale(MRS) and Barthel index(BI), swallowing ability by functional oral intake scale, nutritional status via mini nutritional assessment, life quality through EuroQoL-5D, instrumental ADL function by Lawton-Brody IADL Scale(IADL), balance/coordination via Berg Balance Test, walking speed through Usual Gait Speed, cardiopulmonary capability by Six-Minute Walk Test, occupational mobility (amount use/quality) via Motor Activity Log, language through concise Chinese aphasia test, motor function of upper extremities by Fugl-Meyer Assessment and so on.

Eligibility criteria: Inclusion Criteria:

* \>18 y/o
* acute onset of stroke within 30 days
* Modified Rankin Scale 2\~4

Exclusion Criteria:

* patients refused to join post acute care(PAC) program
* hemodynamic unstable
* disease progression

Primary outcomes:
measure: Activity of daily life function
timeFrame: 35 days
measure: Nutritional status
timeFrame: 35 days
measure: Oral intake function
timeFrame: 35 days
measure: Cardiopulmonary capacity
timeFrame: 35 days
measure: Walking speed
timeFrame: 35 days
measure: Upper motor hand function
timeFrame: 35 days
measure: Life quality
timeFrame: 35 days
measure: Balance and coordination
timeFrame: 35 days
measure: Cognition
timeFrame: 35 days
measure: Speech function
timeFrame: 35 days
Secondary outcomes:
Other outcomes:
Locations:
city: Tainan
country: Taiwan
facility: Chi Mei Medical Center
Study officials:
affiliation: Chi Mei Medical Hospital
name: Willy Chou, MD, MS
role: STUDY_DIRECTOR
References: