Clinical trial NCT01665105: Study on the Effect of Electroacupuncture at Both Zusanli and at Both Yanglingquan Acupoints on Cardiovascular Activity
Official title: Study on the Effect of Electroacupuncture at Both Zusanli and at Both Yanglingquan Acupoints on Autonomic Nerve Modulating Cardiovascular Activity , and Skin Blood Flow and Skin Temperature
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Reaction of Autonomic Nervous System
Reaction of Acupuncture
Reaction of Blood Circulation
Keywords: Pulse Rate Variability
Skin Blood Flow
Skin Temperature
Electroacupuncture
Zusanli
Yanglingquan
Lead sponsor: China Medical University Hospital
Sponsor class: OTHER
First posted: 2012-08-15
Enrollment: 24
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this present study was to investigate the effect of electroacupuncture at both Zusanli and at both Yanglingquan acupoints on autonomic nerve modulating cardiovascular activity, and skin blood flow and skin temperature. The investigators use pulse rate variability to investigate autonomic nerve modulates cardiovascular function, and using distant skin blood flow and skin temperature recordings to investigate the relationship between the same names meridian of hand and foot.

Detailed description: A total of 24 adult healthy volunteer were studied, they received the three sessions of sham electroacupuncture, electroacupuncture at Zusanli and electroacupuncture at Yanglingquan, respectively. Each session was divided into three periods of before electroacupuncture, electroacupuncture, and post electroacupuncture. Each period was 20 min in duration. The ahead 15 min of the period was the skin blood flow and skin temperature recordings at Hoku's and Zhongzhu's region of right hand; the final 5 min of the period was pulse rate variability recordings of left hand. The data was storage and analysis in a personal computer.

Eligibility criteria: Inclusion Criteria:

1. healthy volunteers without without cardiac disease, taking medications, smoking
2. before experiment, abstaining from caffeine, alcohol for 8 hours.
3. age between 20-40.

Exclusion Criteria:

1. volunteers with cardiac disease, taking medications, smoking
2. age greater than 40 or less than 20.

Primary outcomes:
measure: From pulse wave, pulse rate variability and skin blood flow to measure cardiovascular activities with electroacupuncture at Zusanli and at Yanglingquan.
timeFrame: each period was 20 min in duration. The parameters of pulse wave, 5-min pulse rate variability were recorded at the end of each period.
Secondary outcomes:
measure: From skin blood flow and skin temperature to measure cardiovascular activities with electroacupuncture at Zusanli and at Yanglingquan.
timeFrame: each period was 20 min in duration. The parameters of skin blood flow and skin temperature were recorded at the end of each period.
Other outcomes:
Locations:
city: Taichung City
country: Taiwan
facility: China Medical University Hospital
Study officials:
affiliation: China Medical University Hospital
name: Ching-Liang Hsieh, professor
role: PRINCIPAL_INVESTIGATOR
References: