Clinical trial NCT04254159: The Effects of Neuromuscular Electrical Stimulation in Older Patients With Asthma
Official title: The Effects of Neuromuscular Electrical Stimulation to Muscle Strength, Functional Capacity and Quality of Life in Older Patients With Asthma: Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Asthma
Keywords: Asthma
Neuromuscular Electrical Stimulation
Quadriceps Muscle Strength
Quality of Life
Lead sponsor: Yeditepe University
Sponsor class: OTHER
Collaborators: name: Kadikoy Municipality Social Life Center
First posted: 2020-02-05
Enrollment: 24
Sex: ALL
Minimum age (years): 65
Maximum age (years): 75
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The aim of the randomized controlled study is to investigate the effects of NMES superimposed on voluntary contraction combined with patient education and exercise training program in patients with chronic obstructive pulmonary disease.

Detailed description: When initial assessments will be completed, patients will be assigned to one of two possible sequences by simple randomization: Superimposed NMES group (SG) or control group (CG).

All volunteers will receive an COPD patient education program for once and conventional physiotherapy exercise program for COPD with the duration of 8 weeks. Additionally, superimposed NMES will be applied on quadriceps muscle of both limbs at the same time with voluntarily contraction of quadriceps muscle in SG.

All patients will be assessed in terms of functional capacity, pulmonary functions, quadriceps muscle endurance and strength, dyspnea, respiratory muscle strength and quality of life at the baseline and at the end of study. Data will be collected from all the patients at baseline and at the end of study (8 weeks) by the same physiotherapist who also will supervise the exercise sessions.

Eligibility criteria: Inclusion Criteria:

1. Having stable asthma
2. Participating to the study in a voluntary basis
3. Being 65 - 75 years old
4. Having 2 point or over score from "Modified Medical Research Council (MMRC)" Dyspnea Scale
5. Being motivated to participate and follow exercise program

Exclusion Criteria:

1. Having an asthma exacerbation in a last month
2. Other respiratory problems
3. Ischemic heart disease
4. Congestive heart disease
5. Pacemaker
6. Acute Cor Pulmonale
7. Neurological Diseases
8. Osteoporosis
9. Smoking

Primary outcomes:
measure: Sit to Stand Test
timeFrame: 8 weeks
measure: Muscle Strength Test
timeFrame: 8 weeks
measure: Six Minute Walking Test
timeFrame: 8 weeks
measure: Asthma Quality of Life Scale (AQOL)
timeFrame: 8 weeks
Secondary outcomes:
measure: Modified Medical Research Council (MMRC) Dyspnea Scale
timeFrame: 8 weeks
measure: Physical Activity Questionnaire for Elderly (PASE)
timeFrame: 8 weeks
measure: Time Up and Go Test
timeFrame: 8 weeks
measure: Pulmonary Function Test
timeFrame: 8 weeks
measure: Respiratory Muscle Strength Testing
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Kadıköy Municipality Social Life Center
state: Kadıköy
Study officials:
References: