Clinical trial NCT03014453: GER Poses a Potential Risk for Late Complications of BPD
Official title: Gastroesophageal Reflux Poses a Potential Risk for Late Complications of BPD: A Prospective Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Gastroesophageal Reflux
Bronchopulmonary Dysplasia
Lead sponsor: Shengjing Hospital
Sponsor class: OTHER
First posted: 2017-01-09
Enrollment: 187
Sex: ALL
Maximum age (years): 32
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Extremely Premature Infants with Bronchopulmonary Dysplasia

Brief summary: Bronchopulmonary dysplasia (BPD) is a common condition in the low birth weight infants. Although most of the BPD symptoms improved after a regular treatment in infancy, there are still a few late complications left such as the frequent respiratory symptoms, a slower weight gain and even sudden death. These late complications have made so much trouble to the healthcare of BPD infants. How to find the risk factors and to reduce the prevalence of these late symptoms becomes necessary. In this study, a cohort of BPD infants was observed with the late complications obtained by a monthly followed up for 18 months after discharge, the prevalence and risk factors of the late complications of BPD were analyzed by logistic regression. As one of the risk factors, GER was verified whether to play a critical role in these late complications.


Eligibility criteria: Inclusion Criteria:

* the extremely premature infants with bronchopulmonary dysplasia

Exclusion Criteria:

* other congenital malformations such as gastrointestinal and or neurogenic disease

Primary outcomes:
measure: the Late Complications of BPD Infants
timeFrame: 18 months
Secondary outcomes:
Other outcomes:
Locations:
city: Shenyang
country: China
facility: Shengjing Hospital
state: Liaoning
Study officials:
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