Clinical trial NCT06807411: Effectiveness of Video-Based Upper Extremity Exercise Program in Parkinson's Disease
Official title: Investigation of the Effectiveness of a Video-Based Exercise Program Targeting Upper Extremity Function in Individuals With Parkinson
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Parkinson Disease
Exercise
Exergame
Therapy
Keywords: parkinson
exergame
serious game
exercise
physiotherapy
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2025-02-04
Enrollment: 30
Sex: ALL
Minimum age (years): 50
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Over the past decade, virtual reality (VR) has been widely recognized as a therapeutic tool that enables neurological patients to interact with simulated environments through multiple sensory channels. Various sensors can be used in VR systems, with Nintendo Wii and Microsoft Kinect being the most popular. Video game-based training, grounded in VR technology, has emerged as a valid, cost-effective, and easily integrated adjunct to conventional therapy in neurorehabilitation. Compared to traditional exercise methods, video game training offers advantages by allowing users to perform physical activities in a safe and controlled environment. However, some studies have reported limited effects, emphasizing the need for more high-quality research to establish the effectiveness of interactive video games in neurological rehabilitation.

This study aims to investigate the effects of a video-based game exercise program targeting the upper extremity in individuals with Parkinson's disease on joint range of motion, proprioception, functionality, postural instability due to kyphotic posture, and quality of life.

Detailed description: Over the past decade, virtual reality (VR) has been widely recognized as a therapeutic tool that enables neurological patients to interact with simulated environments through multiple sensory channels. Various sensors, such as Nintendo Wii and Microsoft Kinect, are commonly used in VR systems. Video game-based training has emerged as a valid, cost-effective, and easily integrated adjunct to conventional therapy in neurorehabilitation, offering a safe and controlled environment for physical activity. However, some studies have reported limited effects, highlighting the need for further high-quality research to establish its effectiveness in neurological rehabilitation.

This study aims to evaluate the effects of a video-based game exercise program targeting the upper extremity in individuals with Parkinson's disease on joint range of motion (ROM), proprioception, functionality, postural instability due to kyphotic posture, and quality of life. Participants will be randomly assigned to either a conventional exercise group or a video-based game exercise group. All participants will receive conventional therapy for 8 weeks, 3 days per week, with 30-minute sessions (24 sessions in total). The video-based game exercise group will undergo the same conventional therapy, with an additional video game-based exercise program using the Becure Extremity ROM device under physiotherapist supervision. The program will include KinectPong, KinectBalloon, ArmRotate, and Uball games. Balance, joint position sense, ROM, functionality, and quality of life parameters will be assessed before and after treatment.

Eligibility criteria: Inclusion Criteria:

* Individuals aged 50-80 with idiopathic Parkinson's disease
* Hoehn and Yahr Scale Stage I to III
* Presence of kyphotic posture

Exclusion Criteria:

* Presence of any other neurological condition
* Any pathology affecting the movement system in addition to Parkinson's disease
* Visual abnormalities
* Cardiovascular conditions that may interfere with treatment
* Dyskinesia
* History of surgery for Parkinson's disease
* Inability to cooperate at a level required to play the games

Primary outcomes:
measure: Balance
timeFrame: From enrollment to the end of treatment at 8 weeks
measure: Joint position sense
timeFrame: From enrollment to the end of treatment at 8 weeks
measure: Range of motion
timeFrame: From enrollment to the end of treatment at 8 weeks
measure: Functionality
timeFrame: From enrollment to the end of treatment at 8 weeks
Secondary outcomes:
measure: Parkinson's Disease Questionnaire (PDQ-39)
timeFrame: From enrollment to the end of treatment at 8 weeks
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medipol University
state: Beykoz
Study officials:
affiliation: Medipol University
name: Burak Menek, PhD
role: PRINCIPAL_INVESTIGATOR
References: