Clinical trial NCT04074005: Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor
Official title: Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cesarean Section
Epidural; Anesthesia
Keywords: Epidural analgesia
Labor pain
Cesarean section rate
Lead sponsor: Mahidol University
Sponsor class: OTHER
First posted: 2019-08-29
Enrollment: 188
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Pregnant women whom admitted in labor ward for delivering baby as well as accept to receive epidural analgesia for labor

Brief summary: The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

Detailed description: Epidural analgesia with local anesthetic and opioid is the efficiently good method to relieve labor pain comparing with intravenous opioid analgesic. Many literatures reported effects epidural analgesia for labor eg. prolonging the duration of second stage of labor, increasing the rate of instrumental delivery: vacuum extraction and forceps assisting labor. Some papers revealed the increasing in the rate of cesarean delivery. The main reason is assume to be a failure to progress labor after epidural analgesia. However, the recent report from Cochrane database systematic review showed no relation of epidural analgesia for labor and the increasing in the rate of cesarean delivery. Various factors that may involve in the increasing in the rate of cesarean delivery including the dilatation of cervix at the time of insertion of epidural catheter, nulliparous, size of the fetus or motor weakness after receiving epidural medication.

The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

Eligibility criteria: Inclusion Criteria:

* Age\>,= 18 years
* Accept epidural analgesia for labor
* ASA classification I-II

Exclusion Criteria:

* Unable to communicate Thai

Primary outcomes:
measure: Incidence of cesarean delivery after epidural analgesia for labor
timeFrame: From epidural catheter insertion to delivery
Secondary outcomes:
measure: Factors affecting rate of cesarean delivery after epidural analgesia for labor
timeFrame: at the time epidural catheter insertion
measure: Efficacy of epidural analgesia for labor
timeFrame: before and after epidural catheter insertion
measure: Side effects of epidural analgesia for labor: nausea and vomiting
timeFrame: From epidural catheter insertion to delivery
measure: Side effects of epidural analgesia for labor: pruritus
timeFrame: From epidural catheter insertion to delivery
measure: Side effects of epidural analgesia for labor: numbness of legs
timeFrame: From epidural catheter insertion to delivery
measure: Side effects of epidural analgesia for labor: motor weakness
timeFrame: From epidural catheter insertion to delivery
Other outcomes:
Locations:
city: Bangkok
country: Thailand
facility: Siriraj Hospital, Mahidol University
Study officials:
affiliation: Mahidol University
name: Patchareya Nivatpumin, M.D.
role: PRINCIPAL_INVESTIGATOR
References: