Clinical trial NCT04172298: The Study on the Relationship Among Meridian, Acupoint and Internal Visceral Organs
Official title: The Study on the Relationship Among Meridian, Acupoint and Internal Visceral Organs
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Meridian
Keywords: Meridian
Internal visceral organs
Zusanli
Shaohai
Acupoint
Lead sponsor: China Medical University Hospital
Sponsor class: OTHER
First posted: 2019-11-21
Enrollment: 33
Sex: ALL
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: BASIC_SCIENCE

Brief summary: The study on the relationship among meridian, acupoint and internal

Detailed description: Meridian system is the pathway of transporting qi and blood, and that distributes all the body. Meridian system connects to internal visceral organs interior, and also connects to joints (or acupoint) exterior. The relationship among meridian, acupoints and internal visceral organs is still unclear. Therefore, the purpose of the present study was to investigate the relationship among meridian, acupoints and internal visceral organs. Total 33 subjects randomly finished three sessional studies as follows: 1) sham electroacupuncture (EA) session: the stainless steels acupuncture needles inserted into the subcutaneous layer of Zusanli (cathode) and Shangjuxu acupints (anion) , and the needles connected to EA stimulator, but no electric discharge for 30 min; 2) Zusanli session: the acupuncture needles inserted into Zusanli (cathode) and Shangjuxu acupoints (anion), and twisting obtain qi, and the needles then connected to EA stimulator, the frequency was 2 Hz, the duration was 30 min, and the intensity was visual slightly muscle contraction; 3) Shaohai session: the methods were identical Zusanli group, but Shaohai acupoint (cathode), and 3 cm below Shaohai (anion) . The major outcome measure was the changes of the percentage of gastric slow wave and dysrhythmia in 30 min electrogastrogram recordings, and the changes of cardiac output and stroke volume in 30 min recordings. Secondary outcome measure was the changes of saliva, blood and urine metabolites.

The investigators predict the results of the present study can test and verify meridian theory of traditional Chinese Medicine, meridian system connects internal visceral organ interior, and connects joint (or acupoint) exterior.

Eligibility criteria: Inclusion Criteria:

1. Gender：male or female.
2. Age：from 20 years old (inclusive) to 50 years old (inclusive).
3. After detailed description of the entire research purpose or process, voluntarily participate in the study and sign the consent form.

Exclusion Criteria:

1. Cancer, congestive hear failured NYHA class\>II, COPD attack.
2. History of esophagus and gastroduodenal surgery、Barrett's esophagus.
3. Can not accept acupuncture points stimulators.
4. Allergic to acupuncture needles.
5. Has a mental illness or is unable to cooperate with the researcher.

Primary outcomes:
measure: electrogastrogram recordings
timeFrame: 30 minutes in duration.
measure: cardiac output
timeFrame: 30 minutes in duration.
measure: cardiac output
timeFrame: 30 minutes in duration.
Secondary outcomes:
Other outcomes:
Locations:
city: Taichung
country: Taiwan
facility: China Medical University Hospital
state: North District
Study officials:
References: