Clinical trial NCT00340054: Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields
Official title: Assessment of Occupational EMF Exposure - Validation of Interview Procedures Used in Brain Tumor Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Brain and Central Nervous System Tumors
Keywords: brain tumor
Lead sponsor: National Institutes of Health Clinical Center (CC)
Sponsor class: NIH
Collaborators: name: National Cancer Institute (NCI)
First posted: 2006-06-21
Enrollment: 108
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no

Brief summary: RATIONALE: Electric and magnetic fields may increase the risk of cancer. Developing interview questions that accurately estimate a person's exposure to electric and magnetic fields may help doctors learn about the long-term effects of workplace exposure.

PURPOSE: This clinical trial is developing interview questions that can be used in estimating workplace exposure to electric and magnetic fields.

Detailed description: OBJECTIVES:

* Validate an interview-based electric and magnetic field exposure (EMF) assessment algorithm against measurements of the time-weighted average magnetic field magnitude used in previous epidemiologic studies.
* Calibrate the parameters in the algorithm in order to improve the exposure estimates.
* Correlate EMF exposure estimates from the algorithm with biologically based metrics measured by new instrumentation.

OUTLINE: Participants respond to questions during a 5- to 15-minute telephone interview concerning workplace exposure to electric and magnetic (EMF) fields. Data is collected during the interview using an exposure assessment algorithm designed to estimate EMF workplace exposure based on participants' responses. The interview-based estimates are then validated against actual field measurements of magnetic field exposure captured by Emdex multiwave monitors located at participating sites.

Eligibility criteria: DISEASE CHARACTERISTICS:

* Meets 1 of the following occupation criteria:

  * Three occupations that primarily work in offices at Lawrence Livermore National Laboratories (LLNL)
  * Three occupations that do nonelectric manual work (e.g., machinists and laborers) at LLNL

PATIENT CHARACTERISTICS:

* Not specified

PRIOR CONCURRENT THERAPY:

* Not specified

Primary outcomes:
measure: Validation of an interview-based electric and magnetic field (EMF) exposure assessment algorithm
measure: Calibration of algorithm parameters
measure: Correlation between EMF exposure estimates from the algorithm with biologically based metrics measured by new instrumentation
Secondary outcomes:
Other outcomes:
Locations:
city: Menlo Park
country: United States
facility: Exponent, Inc.
state: California
city: Cincinnati
country: United States
facility: National Institute for Occupational Safety and Health
state: Ohio
Study officials:
affiliation: National Cancer Institute (NCI)
name: Joseph Coble, DSc
role: STUDY_CHAIR
References:
citation: Kelsh MA, Kheifets L, Smith R. The impact of work environment, utility, and sampling design on occupational magnetic field exposure summaries. AIHAJ. 2000 Mar-Apr;61(2):174-82. doi: 10.1080/15298660008984526.