Clinical trial NCT02984956: Pleth Variability Index and Hypotension
Official title: Hypotension Relationship With Pleth Variability Index In Hip Fracture Patients Who Underwent Spinal Anesthesia
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Hypotension
Pleth Variability Index
Keywords: Hypotension
Pleth variability index
Hip Fracture
Spinal anesthesia
Lead sponsor: Erzincan University
Sponsor class: OTHER
First posted: 2016-12-07
Enrollment: 100
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients who underwent spinal anesthesia for hip fracture

Brief summary: Correct assessment of a patient's volume status is the most important goal for an anesthetist. However, most of the variables used for fluid response evaluation are invasive and technically challenging.Pulse oximeter is a non-invasive, standardized and widely used monitoring method in many countries. Our aim in this study is to investigate the usefulness of the noninvasive pleth variability index to predict hypotension in orthopedic hip fracture patients who underwent spinal anesthesia.


Eligibility criteria: Inclusion Criteria:

* over 65 years old
* Patients to undergo spinal anesthesia

Exclusion Criteria:

* Patients under 65 years old
* Patients to undergo general anesthesia or only sedation
* Patients with cardiac arrhythmia
* Patients with low ventricular ejection fraction
* Heart valve disease patients

Primary outcomes:
measure: Detecting pleth variability index-hypotension relationship
timeFrame: one year
Secondary outcomes:
measure: pleth variability index response to fluid management
timeFrame: one year
measure: Make a differential diagnosis of hypotension with pleth variability index
timeFrame: one year
measure: Correlation between arterial hemoglobin and pleth variability index hemoglobin
timeFrame: one year
Other outcomes:
Locations:
city: Erzincan
country: Turkey
facility: Erzincan University
Study officials:
References:
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citation: Cannesson M, Delannoy B, Morand A, Rosamel P, Attof Y, Bastien O, Lehot JJ. Does the Pleth variability index indicate the respiratory-induced variation in the plethysmogram and arterial pressure waveforms? Anesth Analg. 2008 Apr;106(4):1189-94, table of contents. doi: 10.1213/ane.0b013e318167ab1f.
citation: Zimmermann M, Feibicke T, Keyl C, Prasser C, Moritz S, Graf BM, Wiesenack C. Accuracy of stroke volume variation compared with pleth variability index to predict fluid responsiveness in mechanically ventilated patients undergoing major surgery. Eur J Anaesthesiol. 2010 Jun;27(6):555-61. doi: 10.1097/EJA.0b013e328335fbd1.
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citation: Desebbe O, Boucau C, Farhat F, Bastien O, Lehot JJ, Cannesson M. The ability of pleth variability index to predict the hemodynamic effects of positive end-expiratory pressure in mechanically ventilated patients under general anesthesia. Anesth Analg. 2010 Mar 1;110(3):792-8. doi: 10.1213/ANE.0b013e3181cd6d06.