Clinical trial NCT06249893: Feasibility of Doppler Ultrasound for Pulse Detection in Out-of-Hospital Cardiac Arrest Patients
Official title: Doppler Ultrasound Pulse Detection in Out-of-Hospital Cardiac Arrest Patients: A Feasibility Study.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cardiac Arrest, Out-Of-Hospital
Keywords: Cardiac Arrest
Out-Of-Hospital Cardiac Arrest
OHCA
Ultrasound
Point-Of-Care Ultrasound
POCUS
Pulse Check
POCUS Pulse Check
Doppler Ultrasound
Femoral Artery
Lead sponsor: Medical University of Vienna
Sponsor class: OTHER
Collaborators: name: Ludwig Boltzmann Institute Digital Health and Patient Safety
name: Emergency Medical Service of Vienna
First posted: 2024-02-08
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population comprises non-pregnant adults suffering out-of-hospital cardiac arrest of any cause who are treated with CPR by emergency medical services.

Brief summary: The goal of this prospective observational study is to investigate the feasibility of using doppler point-of-care ultrasound on the femoral artery with a portable device to assess the presence of a pulse in patients suffering from cardiac arrest in the out-of-hospital environment. The main question is how often researchers are successful in acquiring the necessary ultrasound signal in the out-of-hospital environment.

Detailed description: In this prospective observational study, a dedicated research team will be dispatched to cardiac arrest patients treated in the prehospital environment by emergency medical services (EMS). The team will use a portable ultrasound device to identify the femoral artery and conduct a pulsed wave (PW) doppler measurement during chest compressions as well as during chest compression pauses for rhythm analysis and save the recorded images. These ultrasound pulse checks will be conducted in parallel with the normal treatment of the patient, including manual pulse checks, and will only be conducted if ultrasound is possible without interference in the resuscitation. All treatment decisions will rest with the treating EMS team.

Eligibility criteria: Inclusion Criteria:

* Out-of-hospital cardiac arrest treated by EMS
* Minimum age of 18 years

Exclusion Criteria:

* Pregnancy or suspected pregnancy
* Disapproval of the treating EMS team
* Adults under legal guardianship
* Inability to perform femoral artery doppler ultrasound due to limited access to the patient and possible interference with the treating EMS team
* Inability to perform femoral artery doppler ultrasound due to injuries or anatomic abnormalities in the femoral region or necessary emergent medical interventions in the femoral region
* Decision to transfer the patient to the hospital with ongoing CPR for emergent procedures such as extracorporeal CPR before femoral artery doppler ultrasound could be attempted
* Inability to safely perform femoral artery doppler ultrasound due to environmental hazards

Primary outcomes:
measure: Feasibility of femoral artery doppler ultrasound
timeFrame: During cardiac arrest, up to 45 minutes
Secondary outcomes:
measure: Time until ultrasound signal acquisition
timeFrame: During cardiac arrest, up to 45 minutes
measure: Discordance between doppler ultrasound and manual pulse checks.
timeFrame: During cardiac arrest, up to 45 minutes
measure: Correlation of the result of manual pulse checks with doppler peak systolic velocity
timeFrame: During cardiac arrest, up to 45 minutes
measure: Patient factors influencing probability of successful doppler ultrasound image acquisition
timeFrame: After cardiac arrest, through study completion (a maximum of 1 year)
measure: Inter-observer variability in determining the quality of the doppler ultrasound signal.
timeFrame: After cardiac arrest, through study completion (a maximum of 1 year)
Other outcomes:
Locations:
city: Vienna
country: Austria
facility: Emergency Medical Service of Vienna
Study officials:
affiliation: Medical University of Vienna
name: Philipp Metelka, MD
role: PRINCIPAL_INVESTIGATOR
References: