Clinical trial NCT05915793: Combined Effects Of Diaphragm Strengthening And Accessory Muscles Stretchings In Asthma Patients
Official title: Combined Effects of Diaphragm Strengthening and Accessory Muscles Stretchings in Asthma Patients
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Asthma
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-06-23
Enrollment: 42
Sex: ALL
Minimum age (years): 20
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Asthma is a multifactorial and chronic inflammatory disease in older patients affecting many people worldwide with high cost of pharmacological treatment and physiotherapy interventions. It is characterized by a variety of symptoms including airway inflammation, bronchial hyper-responsiveness, and transient and reversible airway obstruction. Typical clinical features include wheezing, coughing, resting and/or exertional dyspnea, and chest tightness. Lung hyperinflation affects ability to inspire and increases the work of breathing.

Long and short acting corticosteroids and leukotriene are considered effective pharmacological interventions while inspiratory muscle training, incentive spirometry, purse lip breathing, and diaphragm strengthening are considered effective physiotherapy interventions for asthma patients. To find the combined effects of diaphragm strengthening and accessory muscle stretching on chest expansion, pulmonary function, dyspnea and exercise capacity in asthmatic patients. A randomized controlled trial will be conducted at Gulab Davi teaching Hospital Lahore through convenient sampling technique on 40 patients which will be allocated through concealed opaque envelop into Group A and Group Pretreatment values of pulmonary function and chest expansion will be recorded. And patient's perception of exertion through Modified Borg's rating of perceived exertion (RPE) and HRQOL for quality of life will be assessed before and after treatment. Group A will be treated with diaphragm strengthening and Group B will be treated with diaphragm strengthening and accessory muscles stretching. Treatment evaluation will be done after 4 weeks. Data will be analyzed using SPSS software version 25. After assessing normality of data by Shapiro-Wilk test, it will be decided either parametric or non-parametric test will be use within a group or between two groups.


Eligibility criteria: Inclusion Criteria:

* Age group of 40-65 years
* Both male and females
* Phase-2 asthma patients
* Patients hemodynamically stable

Exclusion Criteria:

* Patients having pulmonary tumors
* Patients of Having cough and sputum
* Patients having TB and emphysema
* Patients with pneumonia, pneumonectomy or other lungs surgical procedures

Primary outcomes:
measure: Modified Borg scale of exertion
timeFrame: 6 weeks
measure: 6 MWT
timeFrame: 6 weeks
Secondary outcomes:
measure: Quality of life questionnaire
timeFrame: 6 weeks
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Gulab Devi Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Ameena Amjad, tDPT
role: PRINCIPAL_INVESTIGATOR
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