Clinical trial NCT05116488: Detection of Electrocardiographic Brugada Patterns Using High Precordial Leads
Official title: Detection of Electrocardiographic Brugada Patterns Using High Precordial Leads Positioning Among Asymptomatic Upper Egyptian Population
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Brugada ECG Patterns
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2021-11-11
Enrollment: 300
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study will include patients fulfilling our criteria presenting to cardiology outpatient clinic and emergency room of Assiut University hospitals.

All patients will be subjected to:

A. Full history taking: including age, sex, history of DM, HTN, Smoking, dyslipidaemia symptoms of heart failure, symptoms of Coronary artery disease, and history of any previous arrhythmia.

B. Full Physical examination:

* General examination Systolic and diastolic blood pressure and heart rate assessment.
* Cardiac examination. C. Laboratory investigations: electrolytes ( to make sure they are within normal).

D. Standard 12lead ECG. E .High precordial ECG: to increase sensitivity of Brugada patterns detection. F. Echocardiography: to exclude structural heart disease.

Brief summary: Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population.

Detailed description: Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population.

The study will include patients fulfilling our criteria presenting to cardiology outpatient clinic and emergency room of Assiut University hospitals.

Eligibility criteria: Inclusion Criteria:

1. patients with IHD,HTN,DM with no organic heart disease by ECHO.
2. healthy persons with normal structure heart by ECHO.

Exclusion Criteria:

1. Acute coronary syndrome.
2. cardiomyopathy.
3. severe valvular heart disease.
4. HTN heart disease with LVH.
5. Malignancy.

Primary outcomes:
measure: Detection of electrocardiographic Brugada patterns using high precordial leads positioning among asymptomatic upper Egyptian population
timeFrame: up to 4 hours for each case to make sure of meeting eligibility criteria
Secondary outcomes:
measure: Follow up of positive cases
timeFrame: six months after diagnosis of Brugada pattern for each case
Other outcomes:
Locations:
Study officials:
affiliation: Assiut University
name: Salah Eldin Sayed Atta, Professor
role: STUDY_DIRECTOR
affiliation: Assiut University
name: Mahmoud Abdelsabour, Lecturer
role: STUDY_DIRECTOR
References:
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