Clinical trial NCT04311554: Aging With Dignity, Health, Optimism and Community
Official title: Aging With Dignity, Health, Optimism and Community
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: HIV
Keywords: HIV
PLWH
Aging
Older
Lead sponsor: Mazonson & Santas Inc.
Sponsor class: INDUSTRY
Collaborators: name: Peter Shalit MD and Associates
name: Red River Family Practice
name: Central Texas Clinical Research
name: Rosedale Infectious Diseases
name: Midland Medical Center
name: Anthony Mills MD Inc
name: Stanford University
name: Whitman-Walker Institute
name: University of California, San Diego
name: Ruth M. Rothstein CORE Center
name: University of Wisconsin, Madison
name: ViiV Healthcare
First posted: 2020-03-17
Enrollment: 1049
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: People over the age of 50 with an HIV-1 or -2 infection.

Brief summary: ADHOC is an observational study of people living with HIV over the age of 50. Data from this study will be used to research the interaction between HIV and aging.

Detailed description: ADHOC is an observational study that collects data on PLWH over the age of 50 using an online questionnaire. The questionnaire includes information on sociodemographic factors, activities and interests, HIV diagnosis and status, health care use and satisfaction, antiretroviral therapy, comorbid medical conditions, health and well-being, substance use, and sexual practices.

Eligibility criteria: Eligibility criteria:

* have an HIV-1 or -2 infection,
* be ≥ 50 years of age,
* have no known acute medical problems requiring immediate inpatient treatment,
* be able to read and write in English, and
* be able and willing to provide online informed consent and complete the profile online.

Primary outcomes:
measure: Change in loneliness
timeFrame: Through study completion, an average of 1 year
measure: Loneliness at baseline
timeFrame: Baseline
measure: Change in quality of life
timeFrame: Through study completion, an average of 1 year
measure: Quality of life at baseline
timeFrame: Baseline
measure: Change in cognitive function
timeFrame: Through study completion, an average of 1 year
measure: Cognitive function at baseline
timeFrame: Baseline
measure: Change in social well-being
timeFrame: Through study completion, an average of 1 year
measure: Social well-being at baseline
timeFrame: Baseline
measure: Change in depression
timeFrame: Through study completion, an average of 1 year
measure: Depression at baseline
timeFrame: Baseline
measure: Change in anxiety
timeFrame: Through study completion, an average of 1 year
measure: Anxiety at baseline
timeFrame: Baseline
measure: Change in sleep quality
timeFrame: Through study completion, an average of 1 year
measure: Sleep quality at baseline
timeFrame: Baseline
measure: Change in alcohol use
timeFrame: Through study completion, an average of 1 year
measure: Alcohol use at baseline
timeFrame: Baseline
measure: Change in self-perceived stigma
timeFrame: Through study completion, an average of 1 year
measure: Self-perceived stigma at baseline
timeFrame: Baseline
measure: Change in lipodystrophy
timeFrame: Through study completion, an average of 1 year
measure: Lipodystrophy at baseline
timeFrame: Baseline
measure: Change in resilience
timeFrame: Through study completion, an average of 1 year
measure: Resilience at baseline
timeFrame: Baseline
measure: Change in interpersonal support
timeFrame: Through study completion, an average of 1 year
measure: Interpersonal support at baseline
timeFrame: Baseline
measure: Change in anti-HIV medication adherence
timeFrame: Through study completion, an average of 1 year
measure: Anti-HIV medication adherence at baseline
timeFrame: Baseline
measure: Change in frailty
timeFrame: Through study completion, an average of 1 year
measure: Frailty at baseline
timeFrame: Baseline
Secondary outcomes:
measure: Demographic characteristics
timeFrame: Baseline, and once a year through study completion.
Other outcomes:
Locations:
city: Larkspur
country: United States
facility: Mazonson & Santas Inc
state: California
Study officials:
References: