Clinical trial NCT03466411: A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease
Official title: A Phase 2/3, Randomized, Double-blind, Placebo- and Active-controlled, Parallel-group, Multicenter Protocol to Evaluate the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: PHASE2
PHASE3
Conditions: Crohn's Disease
Lead sponsor: Janssen Research & Development, LLC
Sponsor class: INDUSTRY
First posted: 2018-03-15
Enrollment: 1409
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

Detailed description: This program consists of 3 separate studies: a 48-week Phase 2 dose-ranging study (GALAXI 1) and two 48-week Phase 3 confirmatory studies (GALAXI 2 and GALAXI 3). In Phase 2, safety and efficacy of guselkumab dose regimens will be evaluated to support the selection of induction and maintenance dose regimens for confirmatory evaluation in Phase 3. Participants who complete the 48-week Phase 2 or Phase 3 studies may be eligible to enter the long term extension (LTE). Throughout the 3 studies, efficacy, pharmacokinetic, biomarkers, and safety will be assessed.

Eligibility criteria: Inclusion Criteria:

* Have Crohn's disease (CD) or fistulizing Crohn's disease of at least 3 months duration (defined as a minimum of 12 weeks), with colitis, ileitis, or ileocolitis, confirmed at any time in the past by radiography, histology, and/or endoscopy
* Have moderate to severe CD as assessed by CDAI, stool frequency (SF), and abdominal pain (AP) scores, and Simple Endoscopic Score for Crohn's Disease (SES-CD)
* Have screening laboratory test results within the protocol specified parameters
* A female participant of childbearing potential must have a negative urine pregnancy test result at screening and baseline
* Demonstrated intolerance or inadequate response to conventional or to biologic therapy for CD

Exclusion Criteria:

* Current diagnosis of ulcerative colitis or indeterminate colitis
* Has complications of Crohn's disease, such as symptomatic strictures or stenoses, short gut syndrome, or any other manifestation
* Unstable doses of concomitant Crohn's disease therapy
* Receipt of Crohn's disease approved biologic agents, investigational agents, or procedures outside of permitted timeframe as specified in the protocol
* Any medical contraindications preventing study participation

Primary outcomes:
measure: GALAXI 1: Change From Baseline in the Crohn's Disease Activity Index (CDAI) Score at Week 12
timeFrame: Baseline and Week 12
measure: Global: GALAXI 2: Percentage of Participants With Both Clinical Response at Week 12 and Clinical Remission at Week 48
timeFrame: Weeks 48
measure: Global: GALAXI 2: Percentage of Participants With Both Clinical Response (CR) at Week 12 and Endoscopic Response (ER) at Week 48
timeFrame: Weeks 48
measure: Global: GALAXI 3: Percentage of Participants With Both Clinical Response at Week 12 and Clinical Remission at Week 48
timeFrame: Weeks 48
measure: Global: GALAXI 3: Percentage of Participants With Both Clinical Response (CR) at Week 12 and Endoscopic Response (ER) at Week 48
timeFrame: Weeks 48
measure: Regional: GALAXI 2: Percentage of Participants With Clinical Remission at Week 12
timeFrame: Week 12
measure: Regional: GALAXI 2: Percentage of Participants With Endoscopic Response at Week 12
timeFrame: Week 12
measure: Regional: GALAXI 3: Percentage of Participants With Clinical Remission at Week 12
timeFrame: Week 12
measure: Regional: GALAXI 3: Percentage of Participants With Endoscopic Response at Week 12
timeFrame: Week 12
Secondary outcomes:
measure: GALAXI 1: Percentage of Participants With Clinical Remission at Week 12
timeFrame: At Week 12
measure: GALAXI 1: Percentage of Participants With Clinical Response at Week 12
timeFrame: At Week 12
measure: GALAXI 1: Percentage of Participants With Patient-Reported Outcome (PRO) 2 Remission at Week 12
timeFrame: At Week 12
measure: GALAXI 1: Percentage of Participants With Clinical-Biomarker Response at Week 12
timeFrame: At Week 12
measure: GALAXI 1: Percentage of Participants With Endoscopic Response at Week 12
timeFrame: At Week 12
measure: Global: GALAXI 2 and 3: Percentage of Participants With Clinical Response at Week 4
timeFrame: At Week 4
measure: Global: GALAXI 2 and 3: Percentage of Participants With Clinical Remission at Week 12
timeFrame: At Week 12
measure: Global: GALAXI 2 and 3: Percentage of Participants With Endoscopic Response at Week 12
timeFrame: At Week 12
measure: Global: GALAXI 2 and 3: Percentage of Participants With Fatigue Response at Week 12
timeFrame: At Week 12
measure: Global: GALAXI 2 and 3: Percentage of Participants With Both Clinical Remission and Endoscopic Response at Week 12
timeFrame: At Week 12
measure: Global: GALAXI 2 and 3: Percentage of Participants With Endoscopic Remission at Week 12
timeFrame: At Week 12
measure: Global: GALAXI 2 and 3: Percentage of Participants With Both Clinical Response at Week 12 and Corticosteroid-Free Clinical Remission at Week 48
timeFrame: At Week 48
measure: Global: GALAXI 2 and 3: Percentage of Participants With Both Clinical Response at Week 12 and Endoscopic Remission at Week 48
timeFrame: At Week 48
measure: Global: GALAXI 2 and 3: Percentage of Participants With Clinical Remission at Week 48
timeFrame: At Week 48
measure: Global: GALAXI 2 and 3: Percentage of Participants With Endoscopic Response at Week 48
timeFrame: At Week 48
measure: Global: GALAXI 2 and 3: Percentage of Participants With Both Clinical Remission and Endoscopic Response at Week 48
timeFrame: At Week 48
measure: Global: GALAXI 2 and 3: Percentage of Participants With Endoscopic Remission at Week 48
timeFrame: At Week 48
measure: Global: GALAXI 2 and 3: Percentage of Participants With Deep Remission at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With PRO-2 Remission at Week 12
timeFrame: At Week 12
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Fatigue Response at Week 12
timeFrame: At Week 12
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Endoscopic Remission at Week 12
timeFrame: At Week 12
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Corticosteroid-free Clinical Remission at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Endoscopic Response at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Endoscopic Remission at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Clinical Remission at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Durable Clinical Remission at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With PRO-2 Remission at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Both Clinical Remission at Week 48 and Endoscopic Response at Week 48
timeFrame: At Week 48
measure: Regional: GALAXI 2 and 3: Percentage of Participants With Corticosteroid-free Remission at Week 48
timeFrame: At Week 48
Other outcomes:
Locations:
city: Dothan
country: United States
facility: Digestive Health Specialists of the Southeast
state: Alabama
city: Mobile
country: United States
facility: Internal Medicine Center
state: Alabama
city: Tucson
country: United States
facility: University of Arizona
state: Arizona
city: Anaheim
country: United States
facility: Advanced Research Center Inc
state: California
city: Beverly Hills
country: United States
facility: Paul Wallace MD
state: California
city: La Jolla
country: United States
facility: University Of California San Diego
state: California
city: Lancaster
country: United States
facility: Om Research LLC
state: California
city: Mission Viejo
country: United States
facility: Allameh Medical Corp
state: California
city: Murrieta
country: United States
facility: United Gastroenterologists
state: California
city: Orange
country: United States
facility: Clinnova Research
state: California
city: Rialto
country: United States
facility: Inland Empire Liver Foundation
state: California
city: Sacramento
country: United States
facility: UC Davis Medical Center
state: California
city: San Diego
country: United States
facility: Clinical Applications Laboratories, Inc
state: California
city: Colorado Springs
country: United States
facility: Peak Gastroenterology Associates
state: Colorado
city: Coconut Creek
country: United States
facility: Pioneer Research Solutions Inc.
state: Florida
city: Fort Lauderdale
country: United States
facility: InvesClinic, LLC
state: Florida
city: Hialeah
country: United States
facility: Harmony Medical Research Institute, Inc.
state: Florida
city: Inverness
country: United States
facility: Elite Research Network - Nature Coast Clinical Research, LLC
state: Florida
city: Kissimmee
country: United States
facility: SIH Research
state: Florida
city: Lakeland
country: United States
facility: Auzmer Research
state: Florida
city: Lakewood Ranch
country: United States
facility: Florida Research Center Inc.
state: Florida
city: Miami
country: United States
facility: Homestead Associates in Research Inc
state: Florida
city: Miami
country: United States
facility: Community Research Foundation, Inc.
state: Florida
city: Miami
country: United States
facility: Sanchez Clinical Research, Inc
state: Florida
city: Miami
country: United States
facility: Visionary Investigators Network
state: Florida
city: Naples
country: United States
facility: Gastroenterology Group Of Naples
state: Florida
city: Orlando
country: United States
facility: Florida Hospital
state: Florida
city: Orlando
country: United States
facility: Omega Research Consultants
state: Florida
city: Orlando
country: United States
facility: Care Access Research, Orlando
state: Florida
city: Pinellas Park
country: United States
facility: Synexus Clinical Research US Inc
state: Florida
city: Saint Cloud
country: United States
facility: Central Florida Internists
state: Florida
city: Saint Petersburg
country: United States
facility: Synergy Clinical Research
state: Florida
city: Saint Petersburg
country: United States
facility: Theia Clincial Research, LLC
state: Florida
city: Tampa
country: United States
facility: Clinical Research of West Florida
state: Florida
city: Tampa
country: United States
facility: GCP Clinical Research
state: Florida
city: Tampa
country: United States
facility: Florida Hospital Tampa
state: Florida
city: Tampa
country: United States
facility: Alliance Clinical Research
state: Florida
city: Weston
country: United States
facility: Cleveland Clinic Florida
state: Florida
city: Atlanta
country: United States
facility: Atlanta Gastroenterology Associates
state: Georgia
city: Atlanta
country: United States
facility: Morehouse School of Medicine
state: Georgia
city: Atlanta
country: United States
facility: Emory University
state: Georgia
city: Decatur
country: United States
facility: Atlanta Center For Gastroenterology
state: Georgia
city: Roswell
country: United States
facility: Gastroenterology Consultants
state: Georgia
city: Suwanee
country: United States
facility: Atlanta Gastroenterology Specialists PC
state: Georgia
city: Urbana
country: United States
facility: Carle Foundation Hospital
state: Illinois
city: Indianapolis
country: United States
facility: IU Health University Hospital
state: Indiana
city: Leawood
country: United States
facility: BVL Clinical Research
state: Kansas
city: Pratt
country: United States
facility: Health Science Research Center
state: Kansas
city: Topeka
country: United States
facility: Cotton O'Neil Digestive Health Center
state: Kansas
city: Baton Rouge
country: United States
facility: Gastroenterology Associates
state: Louisiana
city: Lafayette
country: United States
facility: Gastroenterology Clinic of Acadiana
state: Louisiana
city: Marrero
country: United States
facility: Tandem Clinical Research
state: Louisiana
city: New Orleans
country: United States
facility: Ochsner Clinic Foundation
state: Louisiana
city: New Orleans
country: United States
facility: DelRicht Research
state: Louisiana
city: Shreveport
country: United States
facility: LSUHSC Shreveport Feist-Weiller Cancer Center
state: Louisiana
city: Shreveport
country: United States
facility: Louisiana Research Center, LLC
state: Louisiana
city: Baltimore
country: United States
facility: Woodholme Gastroenterology Associates
state: Maryland
city: Chelmsford
country: United States
facility: Digestive Health Specialists PC
state: Massachusetts
city: Chesterfield
country: United States
facility: Clinical Research Institute of Michigan, LLC
state: Michigan
city: Ypsilanti
country: United States
facility: Huron Gastroenterology Associates Center for Digestive Care
state: Michigan
city: Las Vegas
country: United States
facility: Las Vegas Medical Research
state: Nevada
city: Morristown
country: United States
facility: Atlantic Digestive Health Institute/ Atlantic IBD Center
state: New Jersey
city: Jackson Heights
country: United States
facility: A1 Clinical Research
state: New York
city: New York
country: United States
facility: Weill Cornell Medical College
state: New York
city: New York
country: United States
facility: New York Gastroenterology Associates
state: New York
city: New York
country: United States
facility: Care Access Research
state: New York
city: New York
country: United States
facility: NYU Langone Medical Center
state: New York
city: Rochester
country: United States
facility: University of Rochester Medical Center
state: New York
city: Syracuse
country: United States
facility: Syracuse VA Medical Center
state: New York
city: Asheville
country: United States
facility: Asheville Gastroenterology Associates
state: North Carolina
city: Chapel Hill
country: United States
facility: University North Carolina at Chapel Hill
state: North Carolina
city: Charlotte
country: United States
facility: Charlotte Gastroenterology and Hepatology, PLLC
state: North Carolina
city: Charlotte
country: United States
facility: Onsite Clinical Solutions
state: North Carolina
city: Fayetteville
country: United States
facility: Cumberland Research Associates
state: North Carolina
city: Kinston
country: United States
facility: Care Access Research, Kinston
state: North Carolina
city: Mount Airy
country: United States
facility: Clinical Trials of America
state: North Carolina
city: Winston-Salem
country: United States
facility: PMG Research of Winston-Salem
state: North Carolina
city: Beavercreek
country: United States
facility: Clinical Inquest Center, LTD
state: Ohio
city: Columbus
country: United States
facility: Ohio State University
state: Ohio
city: Columbus
country: United States
facility: Synexus Clinical Research US Inc
state: Ohio
city: Mentor
country: United States
facility: Great Lakes Gastroenterology Research, LLC
state: Ohio
city: Poland
country: United States
facility: Southwoods Health
state: Ohio
city: Westlake
country: United States
facility: Northshore Gastroenterology Research, LLC
state: Ohio
city: Oklahoma City
country: United States
facility: Integris Baptist Office
state: Oklahoma
city: Wyomissing
country: United States
facility: US Digestive Health
state: Pennsylvania
city: Anderson
country: United States
facility: Synexus Clinical Research US Inc
state: South Carolina
city: Greenville
country: United States
facility: Gastroenterology Associates P.A.
state: South Carolina
city: Chattanooga
country: United States
facility: Memorial Health Care System
state: Tennessee
city: Germantown
country: United States
facility: Gastro One
state: Tennessee
city: Johnson
country: United States
facility: Tennessee State University
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt University Medical Center
state: Tennessee
city: Garland
country: United States
facility: DHAT Research Institute
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine
state: Texas
city: Houston
country: United States
facility: Houston Methodist Hospital
state: Texas
city: Houston
country: United States
facility: Houston Digestive Diseases Consultants
state: Texas
city: Houston
country: United States
facility: CliniCore Houston
state: Texas
city: Lubbock
country: United States
facility: Caprock Gastro Research
state: Texas
city: San Antonio
country: United States
facility: Gastroenterology Clinic Of San Antonio P A
state: Texas
city: San Antonio
country: United States
facility: Gastroenterology Research of America, LLC
state: Texas
city: San Antonio
country: United States
facility: UT Health Science Center at San Antonio
state: Texas
city: Southlake
country: United States
facility: Texas Digestive Disease Consultants
state: Texas
city: Spring
country: United States
facility: Texas Gastroenterology Associates - Research
state: Texas
city: Temple
country: United States
facility: Baylor Scott and White Research Institute
state: Texas
city: Tyler
country: United States
facility: Tyler Research Institute, LLC
state: Texas
city: Chesapeake
country: United States
facility: Gastroenterology Associates of Tidewater
state: Virginia
city: Petersburg
country: United States
facility: Center for Gastrointestinal Health
state: Virginia
city: Roanoke
country: United States
facility: Gastroenterology Consultants of Southwest Virginia
state: Virginia
city: Bellevue
country: United States
facility: Northwest Gastroenterology Associates - USA
state: Washington
city: Tacoma
country: United States
facility: Washington Gastroenterology, PLLC
state: Washington
city: Adelaide
country: Australia
facility: The Queen Elizabeth Hospital
city: Clayton
country: Australia
facility: Monash Health, Monash Medical Centre
city: Concord
country: Australia
facility: Concord Hospital
city: Heidelberg
country: Australia
facility: Austin Hospital
city: Nedlands
country: Australia
facility: Sir Charles Gairdner Hospital
city: North Terrace
country: Australia
facility: Royal Adelaide Hospital
city: Parkville
country: Australia
facility: Royal Melbourne Hospital
city: Penrith
country: Australia
facility: Nepean Hospital
city: Prahran
country: Australia
facility: The Alfred Hospital
city: South Brisbane
country: Australia
facility: Mater Hospital Brisbane
city: Woolloongabba
country: Australia
facility: Princess Alexandra Hospital
city: Salzburg
country: Austria
facility: Universitaetsklinikum Salzburg Landeskrankenhaus
city: Wien
country: Austria
facility: Akh Wien
city: Gomel
country: Belarus
facility: Gomel Regional Clinical Hospital
city: Gomel
country: Belarus
facility: Republican Research Centre of Radiation Medicine and Human E
city: Grodno
country: Belarus
facility: Grodno University Hospital
city: Minsk
country: Belarus
facility: Healthcare Institution,Minsk Scientific center for surgery,
city: Vitebsk
country: Belarus
facility: Vitebsk Regional Clinical Hospital
city: Brasschaat
country: Belgium
facility: AZ Klina
city: Bruxelles
country: Belgium
facility: CHU Saint-Pierre
city: Bruxelles
country: Belgium
facility: Hopital Erasme
city: Gent
country: Belgium
facility: UZ Gent
city: Kortrijk
country: Belgium
facility: Az Groeninge
city: Roeselare
country: Belgium
facility: Algemeen Ziekenhuis Delta
city: Tournai
country: Belgium
facility: CHwapi
city: Banja Luka
country: Bosnia and Herzegovina
facility: University Clinical Centre of the Republic of Srpska
city: Mostar
country: Bosnia and Herzegovina
facility: Clinical hospital Mostar
city: Sarajevo
country: Bosnia and Herzegovina
facility: Clinical Center University of Sarajevo
city: Sarajevo
country: Bosnia and Herzegovina
facility: Polyclinic Dr. Al-Tawil
city: Zenica
country: Bosnia and Herzegovina
facility: Cantonal Hospital Zenica
city: Blumenau
country: Brazil
facility: MK Blumenau Pesquisa Clínica
city: Botucatu
country: Brazil
facility: Universidade Estadual Paulista 'Julio De Mesquita Filho'
city: Brasilia
country: Brazil
facility: L2IP Instituto de Pesquisas Clinicas
city: Campinas
country: Brazil
facility: Sociedade Campineira de Educacao e Instrucao Hospital e Maternidade Celso Pierro
city: Curitiba
country: Brazil
facility: Hospital Nossa Senhora Das Gracas
city: Goiania
country: Brazil
facility: Inst Goiano Gastroenterologia e Endoscopia Digest Ltda - Clinica de Gastro
city: Jau
country: Brazil
facility: Centro de Estudos Clínicos do Interior Paulista - CECIP
city: Juiz de Fora
country: Brazil
facility: CMIP - Centro Mineiro de Pesquisa Ltda
city: Niterói
country: Brazil
facility: Complexo Hospitalar de Niteroi
city: Passo Fundo
country: Brazil
facility: Instituto Mederi de Pesquisa e Saude
city: Porto Alegre
country: Brazil
facility: Hospital das Clinicas de Porto Alegre
city: Porto Alegre
country: Brazil
facility: Instituto do Aparelho Digestivo
city: Rio de Janeiro
country: Brazil
facility: Universidade Federal do Rio de Janeiro - Faculdade de Medicina
city: Salvador
country: Brazil
facility: Hospital Santa Izabel
city: Santo Andre
country: Brazil
facility: Pesquisare Saude
city: Santo Andre
country: Brazil
facility: Praxis pesquisa médica
city: Santo André
country: Brazil
facility: CEMEC - Centro Multidisciplinar de Estudos Clínicos
city: Santos São Paulo
country: Brazil
facility: Irmandade da Santa Casa da Misericórdia de Santos
city: Sao Jose do Rio Preto
country: Brazil
facility: Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto Hospital de Base
city: Sao Paulo
country: Brazil
facility: Hemomed
city: Sao Paulo
country: Brazil
facility: BR Trials
city: São José Do Rio Preto
country: Brazil
facility: Kaiser Hospta
city: São Paulo
country: Brazil
facility: CPCLIN - Centro de Pesquisas Clínicas
city: Teresina
country: Brazil
facility: Fundacao Universidade Federal do Piaui - Universidade Federal do Piaui
city: Calgary
country: Canada
facility: University of Calgary
state: Alberta
city: Edmonton
country: Canada
facility: Gastroenterology and Internal Medicine Research Institute (GIRI)
state: Alberta
city: Edmonton
country: Canada
facility: University of Alberta- Ziedler Ledcor Centre
state: Alberta
city: New Westminster
country: Canada
facility: Columbia Gastroenterology
state: British Columbia
city: Winnipeg
country: Canada
facility: Health Sciences Centre
state: Manitoba
city: Barrie
country: Canada
facility: Barrie GI Associates
state: Ontario
city: London
country: Canada
facility: London Health Sciences Centre
state: Ontario
city: Toronto
country: Canada
facility: Mount Sinai Hospital-Toronto
state: Ontario
city: Waterloo
country: Canada
facility: Pharmaceutical Integrated Research Company
state: Ontario
city: Montreal
country: Canada
facility: MUHC Montreal General Hospital
state: Quebec
city: Saskatoon
country: Canada
facility: Royal University Hospital
state: Saskatchewan
city: Beijing
country: China
facility: Peking University First Hospital
city: Beijing
country: China
facility: Beijing Friendship Hospital
city: Beijing
country: China
facility: Peking University Third Hospital
city: Beijing
country: China
facility: The Military General Hospital of Beijing PLA
city: Changsha
country: China
facility: The second Xiangya Hospital of Central South University
city: Changzhou City
country: China
facility: Changzhou No 2 Peoples Hospital
city: Chengdu
country: China
facility: West China Hospital Sichuan University
city: Chongqing
country: China
facility: The Second Affiliated Hospital of Chongqing Medical University
city: Ganzhou
country: China
facility: First Affiliated Hospital of Gannan Medical University
city: Guangzhou
country: China
facility: The First Affiliated Hospital Sun Yat-Sen University
city: Guangzhou
country: China
facility: Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
city: Guangzhou
country: China
facility: ZhuJiang Hospital of Southern Medical University
city: Guangzhou
country: China
facility: Sun Yat-sen University - The Sixth Affiliated Hospital Guangdong Gastrointestinal Hospital
city: Hangzhou
country: China
facility: The Second Affiliated Hospital of Zhejiang University
city: Hangzhou
country: China
facility: Sir Run Run Shaw Hospital Zhejiang University School of Medicine
city: Hefei
country: China
facility: The First Affiliated Hospital of Anhui Medical University
city: Huai'an
country: China
facility: Huai'an 1st Hospital
city: Nanchang
country: China
facility: The First Affiliated Hospital of NanChang University
city: Nanjing
country: China
facility: Nanjing Drum Tower Hospital
city: Nanjing
country: China
facility: Zhongda Hospital Southeast University
city: Shanghai
country: China
facility: Shanghai Ninth Peoples Hospital
city: Shanghai
country: China
facility: Huashan Hospital Fudan University
city: Shanghai
country: China
facility: Second Military Medical University (SMMU)
city: Shanghai
country: China
facility: Tongji Hospital of Tongji University
city: Shanghai
country: China
facility: Ruijin Hospital Shanghai Jiao Tong University
city: Shenyang
country: China
facility: Shengjing Hospital Of China Medical University
city: Shenzhen
country: China
facility: Peking University Shenzhen Hospital
city: Suzhou
country: China
facility: The first affiliated hospital of suzhou University
city: Wenzhou
country: China
facility: The First Affiliated Hospital of Wenzhou Medical University
city: Wuhan
country: China
facility: Wuhan Union Hospital
city: Wuhan
country: China
facility: Renmin Hospital of Wuhan University
city: Wuxi
country: China
facility: Wuxi People s Hospital
city: Xiamen
country: China
facility: Zhongshan Hospital, Xiamen University
city: Yangzhou
country: China
facility: Yangzhou First People's Hospital
city: Zhangzhou
country: China
facility: Zhangzhou Municipal Hospital of Fujian Province
city: Bogota
country: Colombia
facility: Medplus Medicina Prepagada S.A.
city: Bogota
country: Colombia
facility: Clinica de la Mujer
city: Bogota
country: Colombia
facility: Endocare Ltda.
city: Cali
country: Colombia
facility: Centro Médico Imbanaco
city: Medellin
country: Colombia
facility: Corporacion para Estudios en Salud Clinica CES - Gastroenterology
city: Bjelovar
country: Croatia
facility: Opca bolnica Bjelovar
city: Zadar
country: Croatia
facility: Opca bolnica Zadar
city: Zagreb
country: Croatia
facility: CH Sestre Milosrdnice
city: Zagreb
country: Croatia
facility: Poliklinika Solmed
city: Zagreb
country: Croatia
facility: University Hospital Center Zagreb
city: Zagreb
country: Croatia
facility: University Hospital Dubrava
city: Ceske Budejovice
country: Czechia
facility: Nemocnice Ceske Budejovice
city: Horovice
country: Czechia
facility: NH Hospital, a.s.
city: Hradec Kralove
country: Czechia
facility: Hepato-gastroenterologie HK, s.r.o.
city: Prague 2
country: Czechia
facility: Synexus Czech s.r.o.
city: Praha 10
country: Czechia
facility: Fakultni nemocnice Kralovske Vinohrady
city: Praha 9
country: Czechia
facility: ISCARE a.s.
city: Amiens
country: France
facility: CHU Amiens
city: Bayonne
country: France
facility: Centre Hospitalier de la Cote Basque
city: Besancon
country: France
facility: CHRU Besancon Hopital Jean Minjoz
city: Caen
country: France
facility: Centre Hospitalier Universitaire (CHU) de Caen
city: Chambray Les Tours Centre
country: France
facility: CHRU de Tours - Hopital Trousseau
city: Créteil
country: France
facility: Centre Hospitalier Universitaire(CHU) - Hopital Henri Mondor
city: Grenoble
country: France
facility: CHU Grenoble
city: Lille
country: France
facility: CHRU de Lille Hopital Claude Huriez
city: Marseille
country: France
facility: Hopital Nord Marseille
city: Montpellier Cedex 5
country: France
facility: CHRU Montpellier - Hopital Saint-Eloi
city: Nantes
country: France
facility: CHU de Nantes hotel Dieu
city: Nice cedex 03
country: France
facility: CHU de Nice Hopital de l Archet
city: Nimes
country: France
facility: CHU Nimes Hopital Caremeau
city: Paris
country: France
facility: Hôpital Bichat
city: Paris
country: France
facility: Groupement Hospitalier Universitaire Ouest
city: Pierre-Bénite
country: France
facility: Centre Hospitalier Lyon Sud
city: Reims
country: France
facility: Centre Hospitalier Universitaire de Reims, Hôpital Robert Debré
city: Saint Etienne
country: France
facility: CHU Saint Etienne
city: Saint Mandé
country: France
facility: Hopital D'Instruction Des Armees
city: Strasbourg Cedex
country: France
facility: CHRU de Strasbourg - Hopital de Hautepierre
city: Toulouse
country: France
facility: CHU Toulouse - Hopital de Rangueil
city: Toulouse
country: France
facility: Hopital Rangueil
city: Vandoeuvre-les-Nancy
country: France
facility: CHU de Nancy_ Hopital Brabois
city: T'bilisi
country: Georgia
facility: LTD 'Aversi Clinic'
city: Tbilisi
country: Georgia
facility: TSMU The First University Clinic
city: Tbilisi
country: Georgia
facility: Institute of Clinical Cardiology, Ltd.
city: Tbilisi
country: Georgia
facility: LTD 'Georgia Archangel St. Michael Multiprofile Clinical Hospital'
city: Tbilisi
country: Georgia
facility: LTD Helsicore
city: Telavi
country: Georgia
facility: LTD Unimed Kakheti- Telavi Referral Hospital
city: Augsburg
country: Germany
facility: Klinikum Augsburg
city: Berlin-Karlshorst
country: Germany
facility: Gastroenterologische Spezialpraxis - Berlin-Karlshorst
city: Berlin
country: Germany
facility: Charite - Campus Mitte
city: Berlin
country: Germany
facility: Synexus Berlin Research Center
city: Berlin
country: Germany
facility: Universitaetsklinikum Charite, Campus Virchow Klinikum
city: Berlin
country: Germany
facility: Krankenhaus Waldfriede Mitte
city: Dresden
country: Germany
facility: Klinikum Dresden
city: Frankfurt/Main
country: Germany
facility: Agaplesion Frankfurter Diakonie Kliniken GmbH, Markus Krankenhaus
city: Frankfurt
country: Germany
facility: Synexus Clinical Research GmbH
city: Frankfurt
country: Germany
facility: JWG-University Hospital
city: Hamburg
country: Germany
facility: Martini-Klinik am Universitätsklinikum Hamburg-Eppendorf Urologie
city: Hamburg
country: Germany
facility: Asklepios Westklinikum
city: Hannover
country: Germany
facility: Medizinische Hochschule Hannover
city: Heidelberg
country: Germany
facility: Universitaetsklinikum Heidelberg
city: Kiel
country: Germany
facility: Universitatsklinikum Schleswig Holstein Kiel
city: Leipzig
country: Germany
facility: Eugastro GmbH
city: Leipzig
country: Germany
facility: Gastroenterologie und Hepatologie am Johannisplatz
city: Lueneburg
country: Germany
facility: Staedtisches Klinikum Lueneburg
city: Mannheim
country: Germany
facility: Universitaetsklinikum Mannheim
city: Münster
country: Germany
facility: Gemeinschaftspraxis Germania-Campus
city: Regensburg
country: Germany
facility: Praxiszentrum Alte Mälzerei
city: Saarbrücken
country: Germany
facility: Zentrum für Gastroenterologie Saar MVZ GmbH
city: Ulm
country: Germany
facility: Universitatsklinikum Ulm
city: Athens
country: Greece
facility: Laiko General Hospital of Athens
city: Heraklion
country: Greece
facility: University Hospital of Heraklion
city: Budapest
country: Hungary
facility: Synexus Magyarorszag Kft
city: Budapest
country: Hungary
facility: Péterfy Sándor utcai Kórház
city: Budapest
country: Hungary
facility: Meddica Centre Hungarian Defence Froces
city: Budapest
country: Hungary
facility: Semmelweis Egyetem
city: Békéscsaba
country: Hungary
facility: Réthy Pál Kórház - Rendelőintézet
city: Gyula
country: Hungary
facility: Synexus Magyarorszag Kft
city: Szekszárd
country: Hungary
facility: Tolna Megyei Balassa Janos Korhaz
city: Jaipur
country: India
facility: Apex Hospitals Ltd
city: New Delhi
country: India
facility: Fortis Hospital
city: Noida
country: India
facility: Fortis Hospital
city: Rajkot
country: India
facility: Shree Giriraj Multispeciality Hospital
city: Surat
country: India
facility: Nirmal Hospital Pvt. Ltd.
city: Surat
country: India
facility: Surat Institute of Digestive Sciences Hospitals
city: Surat
country: India
facility: BAPS Pramukhswami Hospital
city: Surat
country: India
facility: Unity Hospital
city: Afula
country: Israel
facility: Ha'Emek Medical Center
city: Ashkelon
country: Israel
facility: Barzilai Medical Center
city: Bear Sheva
country: Israel
facility: Soroka Medical Center
city: Haifa
country: Israel
facility: Rambam Medical Center
city: Haifa
country: Israel
facility: Bnai Zion Medical Center
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center
city: Jerusalem
country: Israel
facility: Hadassah Hebrew University Medical Center
city: Kfar Saba
country: Israel
facility: Meir Medical Center
city: Petah Tikva
country: Israel
facility: Rabin Med Ctr Beilinson Hosp
city: Ramat Gan
country: Israel
facility: Chaim Sheba Medical Center
city: Tel Aviv
country: Israel
facility: Tel Aviv Sourasky Medical Center
city: Tzrifin
country: Israel
facility: Assaf Harofeh Medical Center
city: Bologna
country: Italy
facility: Policlinico S.Orsola Malpighi, AOU di Bologna
city: Cagliari
country: Italy
facility: Azienda Ospedaliero Universitaria di Cagliari - Policlinico Duilio Casula di Monserrato
city: Cento
country: Italy
facility: Ospedale Santissima Annunziata
city: Messina
country: Italy
facility: AOU Policlinico G.Martino
city: Milano
country: Italy
facility: Gruppo Ospedaliero San Donato - Istituto di Ricovero e Cura
city: Padova
country: Italy
facility: Universita degli Studi di Padova - Azienda Ospedaliera di Padova
city: Roma
country: Italy
facility: Università Campus Biomedico di Roma
city: Roma
country: Italy
facility: Policlinico Universitario Agostino Gemelli
city: Rome
country: Italy
facility: Complesso Integrato Columbus
city: Rozzano
country: Italy
facility: IRCCS Humanitas Rozzano-IBD Center Malattie Infiammatorie Croniche Intestinali
city: San Giovanni Rotondo
country: Italy
facility: Casa Sollievo della Sofferenza
city: Torino
country: Italy
facility: S.C. Gastroenterologia
city: Udine
country: Italy
facility: Azienda Ospedaliero Universitaria S.Maria Della Misericordia
city: Verona
country: Italy
facility: Policlinico G.B.Rossi
city: Asahikawa
country: Japan
facility: Asahikawa City Hospital
city: Bunkyo Ku
country: Japan
facility: Tokyo Medical and Dental University Hospital
city: Bunkyo-ku
country: Japan
facility: Juntendo University Hospital
city: Bunkyo-ku
country: Japan
facility: Juntendo University Hospital
city: Chiba
country: Japan
facility: Chiba University Hospital
city: Chikushino
country: Japan
facility: Fukuoka University Chikushi Hospital
city: Fukuoka-shi
country: Japan
facility: Saiseikai Fukuoka General Hospital
city: Fukuoka-shi
country: Japan
facility: Fukuoka University Hospital
city: Gifu
country: Japan
facility: Gifu University Hospital
city: Hachioji
country: Japan
facility: Tokai University Hachioji Hospital
city: Hamamatsu-shi
country: Japan
facility: Matsuda Hospital
city: Higashiibaraki-gun
country: Japan
facility: Mito Medical Center - Digestive Organs
city: Hirosaki
country: Japan
facility: National Hospital Organization Hirosaki General Medical Center
city: Hiroshima
country: Japan
facility: Hiroshima University Hospital
city: Ishikawa
country: Japan
facility: National Hospital Organization Kanazawa Medical Center
city: Izumiotsu
country: Japan
facility: Izumiotsu Municipal Hospital
city: Izumo
country: Japan
facility: Shimane University Hospital
city: Kagoshima
country: Japan
facility: Kagoshima IBD Gastroenterology Clinic
city: Kagoshima
country: Japan
facility: Sameshima Hospital
city: Kagoshima
country: Japan
facility: Nanpuh Hospital
city: Kanazawa
country: Japan
facility: Kanazawa University Hospital
city: Kashihara
country: Japan
facility: Nara Medical University Hospital
city: Kashiwa
country: Japan
facility: Tsujinaka Hospital Kashiwanoha
city: Kashiwa
country: Japan
facility: The Jikei University Hospital
city: Kobe
country: Japan
facility: Aoyama Naika Clinic
city: Kobe
country: Japan
facility: Kobe University Hospital
city: Kochi
country: Japan
facility: National Hospital Organization Kochi National Hospital
city: Kofu
country: Japan
facility: Yamanashi Prefectural Central Hospital
city: Kure
country: Japan
facility: National Hospital Organization Kure Medical Center and Chugoku Cancer Center
city: Kurume
country: Japan
facility: Kurume University Hospital
city: Kyoto
country: Japan
facility: University Hospital Kyoto Prefectural University of Medicine
city: Kyoto
country: Japan
facility: JRC Kyoto Daiichi Hospital
city: Kyoto
country: Japan
facility: Kyoto University Hospital
city: Kyoto
country: Japan
facility: National Hospital Organization Kyoto Medical Center
city: Minato-ku
country: Japan
facility: Kitasato University Kitasato Institute Hospital
city: Mitaka
country: Japan
facility: Kyorin University Hospital
city: Morioka
country: Japan
facility: Iwate Medical University Hospital
city: Nagakute
country: Japan
facility: Aichi Medical University Hospital
city: Nagaoka
country: Japan
facility: Nagaoka Red Cross Hospital
city: Nagasaki
country: Japan
facility: Nagasaki University Hospital
city: Nagoya
country: Japan
facility: Nagoya University Hospital
city: Nagoya
country: Japan
facility: Nagoya City University Hospital
city: Nishinomiya
country: Japan
facility: The Hospital of Hyogo College of Medicine
city: Obihiro
country: Japan
facility: JA Obihiro Kosei Hospital
city: Oita
country: Japan
facility: Oita Red Cross Hospital
city: Okayama
country: Japan
facility: Okayama Saiseikai General Hospital
city: Okinawa
country: Japan
facility: Nakagami Hospital
city: Osaka-Sayama
country: Japan
facility: Kindai University Hospital
city: Osaka-shi
country: Japan
facility: National Hospital Organization Osaka National Hospital
city: Osaka
country: Japan
facility: Kinshukai Infusion Clinic
city: Osaka
country: Japan
facility: Kitano Hospital
city: Osaka
country: Japan
facility: Japanese Red Cross Osaka Hospital
city: Osaka
country: Japan
facility: Osaka City University Hospital
city: Osaki
country: Japan
facility: Osaki Citizen Hospital
city: Otsu-shi
country: Japan
facility: National Hospital Organization Higashi Ohmi General Medical Center
city: Otsu
country: Japan
facility: Shiga University of Medical Science Hospital
city: Saitama
country: Japan
facility: Japan Community Health Care Organization Saitama Medical Center
city: Saitama
country: Japan
facility: Tokitokai Tokito Clinic Coloproctology Center
city: Saitama
country: Japan
facility: Saitama Medical University Hospital
city: Sakura
country: Japan
facility: Toho University Sakura Medical Center
city: Sapporo Chuo-ku
country: Japan
facility: Sapporo IBD Clinic
city: Sapporo-shi
country: Japan
facility: Hokkaido University Hospital
city: Sapporo
country: Japan
facility: JA Sapporo-Kosei General Hospital - 1st Digestive Organs
city: Sapporo
country: Japan
facility: Sapporo Higashi Tokushukai Hospital
city: Shinjuku-ku
country: Japan
facility: Tokyo Yamate Medical Center
city: Suita-shi
country: Japan
facility: Osaka University Hospital
city: Takamatsu
country: Japan
facility: Takamatsu Red Cross Hospital
city: Takamatsu
country: Japan
facility: Kagawa Prefectural Central Hospital
city: Tokushima
country: Japan
facility: Tokushima University Hospital
city: Tokyo
country: Japan
facility: The Jikei University Hospital
city: Tomishiro
country: Japan
facility: Yuaikai Tomishiro Central Hospital
city: Toon
country: Japan
facility: Ehime University Hospital
city: Toyama-shi
country: Japan
facility: Toyama City Hospital
city: Toyoake
country: Japan
facility: Fujita Health University Hospital
city: Tsu
country: Japan
facility: Mie University Hospital
city: Wakayama
country: Japan
facility: Wakayama Medical University Hospital
city: Yokohama
country: Japan
facility: Yokohama City University Medical Center
city: Amman
country: Jordan
facility: Khalidi Hospital and Medical Center
city: Amman
country: Jordan
facility: Jordan University Hospital
city: Irbid
country: Jordan
facility: Irbid Specialty Hospital
city: Irbid
country: Jordan
facility: King Abdullah University Hospital
city: Ansan-si
country: Korea, Republic of
facility: Korea University Ansan Hospital
city: Busan
country: Korea, Republic of
facility: Inje University Haeundae Paik Hospital
city: Busan
country: Korea, Republic of
facility: Dong-A University Hospital
city: Daegu
country: Korea, Republic of
facility: Kyongpook national university Medical center
city: Daegu
country: Korea, Republic of
facility: Kyungpook National University Hospital
city: Gyeonggi-do
country: Korea, Republic of
facility: The Catholic university of Korea, St. Vincent's Hospital
city: Hwaseong-si
country: Korea, Republic of
facility: Hallym University Dongtan Sacred Heart Hospital
city: Seongnam-si
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
city: Seongnam
country: Korea, Republic of
facility: CHA Bundang Medical Center, CHA University
city: Seongnam
country: Korea, Republic of
facility: The Catholic Univ. of Korea, DaeJeon St. Mary's Hospital
city: Seoul
country: Korea, Republic of
facility: Kangbuk Samsung Hospital
city: Seoul
country: Korea, Republic of
facility: Yonsei University College of Medicine
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center
city: Seoul
country: Korea, Republic of
facility: Chung-Ang University Hospital
city: Seoul
country: Korea, Republic of
facility: Gangnam Severance Hospital
city: Wonju
country: Korea, Republic of
facility: Wonju Christian Hospital
city: YangCheon-Gu
country: Korea, Republic of
facility: Ewha Womans University Mokdong Hospital
city: Riga
country: Latvia
facility: Pauls Stradins Clinical University Hospital
city: Riga
country: Latvia
facility: Alda Pukisa arsta prakse
city: Ain Wazein
country: Lebanon
facility: Ain Wazein Hospital
city: Beirut
country: Lebanon
facility: American Universitty of Beirut Medical Center
city: Beirut
country: Lebanon
facility: St Georges Hospital university medical centre
city: Beirut
country: Lebanon
facility: Hotel Dieu de France Hospital
city: Beirut
country: Lebanon
facility: Bellevue Medical Center
city: Beirut
country: Lebanon
facility: Mount Lebanon Hospital
city: Beirut
country: Lebanon
facility: Rafik Hariri University Hospital
city: Tripoli
country: Lebanon
facility: Nini Hospital
city: Kaunas
country: Lithuania
facility: Lietuvos sveikatos mokslų universiteto ligoninė Kauno klinik
city: Vilnius
country: Lithuania
facility: Vilnius University Hospital Santaros Klinikos, Public Institution
city: Ampang
country: Malaysia
facility: Hospital Ampang
city: Ipoh
country: Malaysia
facility: Hospital Raja Permaisuri Bainun
city: Johor Bahru
country: Malaysia
facility: Hospital Sultanah Aminah
city: Kota Bahru
country: Malaysia
facility: Hospital Raja Perempuan Zainab Ii
city: Kuala Lumpur
country: Malaysia
facility: University Malaya Medical Centre
city: Kuantan
country: Malaysia
facility: Hospital Tengku Ampuan Afzan
city: Amsterdam
country: Netherlands
facility: Amsterdam UMC locatie VUMC
city: Maastricht
country: Netherlands
facility: Academisch Ziekenhuis Maastricht
city: Sittard-Geleen
country: Netherlands
facility: Stichting Zuyderland Medisch Centrum
city: Auckland
country: New Zealand
facility: Auckland City Hospital
city: Christchurch
country: New Zealand
facility: Christchurch Hospital
city: Dunedin
country: New Zealand
facility: Dunedin Hospital
city: Hamilton
country: New Zealand
facility: Waikato Hospital
city: Skopje
country: North Macedonia
facility: General City Hospital 8mi Septemvri
city: Skopje
country: North Macedonia
facility: University Clinic of Gastroenterohepatology
city: Bydgoszcz
country: Poland
facility: NZOZ Centrum Medyczne KERmed
city: Chojnice
country: Poland
facility: Centrum Medyczne Lukamed
city: Czestochowa
country: Poland
facility: Synexus Polska Sp. z o.o. Oddzial w Czestochowie
city: Gdansk
country: Poland
facility: Synexus Polska Sp. z o.o. Oddzial w Gdansku
city: Gdynia
country: Poland
facility: Synexus Scm Sp Z o o Oddzial Gdynia
city: Jelenia Gora
country: Poland
facility: Prywatna Praktyka Lekarska
city: Katowice
country: Poland
facility: Synexus Polska Sp z o o Oddzial w Katowicach
city: Krakow
country: Poland
facility: Malopolskie Centrum Kliniczne
city: Krakow
country: Poland
facility: Centrum Medyczne Plejady
city: Krakow
country: Poland
facility: Centrum Medyczne Promed
city: Ksawerow
country: Poland
facility: Centrum Opieki Zdrowotnej Orkan Med Stec Michalska sj
city: Lodz
country: Poland
facility: Synexus Polska Sp z o o
city: Lodz
country: Poland
facility: AmiCare Centrum Medyczne
city: Lublin
country: Poland
facility: 1 Wojskowy Szpital Kliniczny Z Poliklinika SPZOZ W Lublinie
city: Lublin
country: Poland
facility: Gastromed Spotka Z Ograniczona Odpowiedzialnoscia Sp. K.
city: Olsztyn
country: Poland
facility: Wojewodzki Szpital Specjalistyczny w Olsztynie
city: Opole
country: Poland
facility: Twoja Przychodnia
city: Oswiecim
country: Poland
facility: Oswiecimskie Centrum Badan Klinicznych
city: Poznan
country: Poland
facility: EMC Instytut Medyczny SA
city: Poznan
country: Poland
facility: Solumed S C
city: Poznan
country: Poland
facility: Synexus Polska Sp. z.o.o. Oddzial w Poznaniu
city: Poznan
country: Poland
facility: Twoja Przychodnia
city: Rzeszow
country: Poland
facility: Centrum Medyczne 'Medyk' Sp. z o.o. K.
city: Sopot
country: Poland
facility: Endoskopia Sp z o.o.
city: Sosnowiec
country: Poland
facility: Kiepury Clinic
city: Szczecin
country: Poland
facility: Twoja Przychodnia - Szczecinskie Centrum Medyczne
city: Szczecin
country: Poland
facility: Niepubliczny Zaklad Opieki Zdrowotnej
city: Torun
country: Poland
facility: GASTROMED Specjalistyczne Centrum Gastrologii i Endoskopii Specjalistyczne Gabinety Lekarskie
city: Tychy
country: Poland
facility: H-T Centrum Medyczne Endoterapia
city: Warsaw
country: Poland
facility: NZOZ Vivamed Zespol Lekarzy Specjalistow
city: Warszawa
country: Poland
facility: Wojskowy Instytut Medyczny
city: Warszawa
country: Poland
facility: Centrum Medyczne
city: Warszawa
country: Poland
facility: Centralny Szpital Kliniczny MSWiA w Warszawie
city: Warszawa
country: Poland
facility: Centrum Badawcze Wspolczesnej Terapii
city: Warszawa
country: Poland
facility: Szpital Pomnik Centrum Zdrowia Dziecka
city: Warszawa
country: Poland
facility: Synexus Polska Sp z o o Oddzial w Warszawie
city: Wierzchoslawice
country: Poland
facility: Centrum Zdrowia Tuchow
city: Wloclawek
country: Poland
facility: Centrum Diagnostyczno - Lecznicze Barska sp. z o.o. Szpital Specjalistyczny Barska
city: Wroclaw
country: Poland
facility: Synexus Polska Sp z o o Oddzial we Wroclawiu
city: Wroclaw
country: Poland
facility: Przychodnia Vistamed
city: Wroclaw
country: Poland
facility: Futuremeds sp. z o.o.
city: Wroclaw
country: Poland
facility: Melita Medical Sp. z o.o.
city: Wroclaw
country: Poland
facility: ARS MEDICA Rybak Maria, Rybak Zbigniew, s.c.
city: Wroclaw
country: Poland
facility: EuroMediCare Szpital Specjalistyczny z Przychodnia
city: Zamosc
country: Poland
facility: ETG Zamosc
city: Braga
country: Portugal
facility: Hospital de Braga
city: Coimbra
country: Portugal
facility: Centro Hospitalar e Universitário de Coimbra, EPE
city: Guimarães
country: Portugal
facility: Uls Alto Ave - Hosp. Sra. Da Oliveira Guimaraes
city: Portimao
country: Portugal
facility: Hospital de Portimao-Centro Hospitalar do Barlavento Algarvio
city: Porto
country: Portugal
facility: H. Santo António - Centro Hospitalar do Porto
city: Santa Maria da Feira
country: Portugal
facility: Centro Hospitalar de Entre o Douro e Vouga, E.P.E
city: Caguas
country: Puerto Rico
facility: San Juan Bautista School of Medicine
city: Kazan
country: Russian Federation
facility: Kazan State Medical University
city: Krasnoyarsk
country: Russian Federation
facility: KGBUZ 'Regional Clinical Hospital'
city: Moscow
country: Russian Federation
facility: State Scientific Centre of Coloproctology
city: Nizhny Novgorod
country: Russian Federation
facility: Novgorod Regional Clinical Hospital n.a. N.A. Semashko
city: Novosibirsk
country: Russian Federation
facility: City Clinical Hospital #12
city: Novosibirsk
country: Russian Federation
facility: FSBI 'Scientific Research Institute of Clinical and Experimental Lymphology' of Siberian Branch
city: Omsk
country: Russian Federation
facility: Clinical Diagnostic Center 'Ultramed'
city: Podolsk
country: Russian Federation
facility: GBUZ of Moscow Region City Clinical Hospital #3
city: Rostov-na-Donu
country: Russian Federation
facility: GBOU VPO Rostov State Medical University
city: Rostov-on-Don
country: Russian Federation
facility: City Hospital #20
city: Saint Petersburg
country: Russian Federation
facility: Clinical Hospital #122 n.a. after L.G. Sokolov
city: Saint-Petersburg
country: Russian Federation
facility: City Hospital named after St. Martyr Elizabeth
city: Saint-Petersburg
country: Russian Federation
facility: The Limited Liability Company Research center Eco-safety
city: Samara
country: Russian Federation
facility: Medical University Reaviz
city: Samara
country: Russian Federation
facility: NUZ 'Railway Clinical Hospital on Samara station of LLC 'Russian Railways'
city: Saratov
country: Russian Federation
facility: Saratov City Hospital #5
city: St Petersburg
country: Russian Federation
facility: St.Petersburg State Medical University n.a.Pavlov
city: St. Petersburg
country: Russian Federation
facility: City Clinical Hospital #31
city: Tomsk
country: Russian Federation
facility: Tomsk Regional Clinical Hospital
city: Ulyanovsk
country: Russian Federation
facility: Ulyanovsk Regional Clinical Hospital
city: Velikiy Novgorod
country: Russian Federation
facility: GUZ Novgorod Regional Clinical Hospital
city: Makkah
country: Saudi Arabia
facility: King Abdullah Medical City in Holy Capital
city: Riyadh
country: Saudi Arabia
facility: King Abdul Aziz Medical City for National Guard Health Affairs
city: Belgrade
country: Serbia
facility: Special hospital for Internal diseases, Oncomed system
city: Belgrade
country: Serbia
facility: University Clinical Center of Serbia
city: Belgrade
country: Serbia
facility: Zvezdara University Medical Center
city: Belgrade
country: Serbia
facility: Clinical Hospital Center Bezanijska Kosa
city: Kragujevac
country: Serbia
facility: University Clinical Center Kragujevac
city: Zrenjanin
country: Serbia
facility: General Hospital 'Djordje Joanovic'
city: Banska Bystrica
country: Slovakia
facility: FNsP F.D.R. Banska Bystrica
city: Kosice
country: Slovakia
facility: ENDOMED s.r.o
city: Presov
country: Slovakia
facility: GASTRO I. s.r.o.
city: Córdoba
country: Spain
facility: Hosp Reina Sofia
city: Ferrol
country: Spain
facility: Complejo Hosp Univ. de Ferrol
city: Girona
country: Spain
facility: Hosp. Univ. Dr. Josep Trueta
city: Huelva
country: Spain
facility: Hosp. Gral. Juan Ramon Jimenez
city: Madrid
country: Spain
facility: Hosp. Univ. La Paz
city: Oviedo
country: Spain
facility: Hosp. Univ. Central de Asturias
city: Pontevedra
country: Spain
facility: Hosp. Provincial de Pontevedra
city: Sevilla
country: Spain
facility: Hosp. Virgen Del Rocio
city: Torrejón de Ardoz
country: Spain
facility: Hosp. Univ. de Torrejon
city: Vigo
country: Spain
facility: Hosp. Alvaro Cunqueiro
city: Zaragoza
country: Spain
facility: Hosp. Univ. Miguel Servet
city: Changhua
country: Taiwan
facility: Chang-Hua Christian Hospital
city: Taichung
country: Taiwan
facility: China Medical University Hospital
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital
city: Taoyuan
country: Taiwan
facility: Chang-Gung Memorial Hospital-Linkou
city: Nabul
country: Tunisia
facility: Hopital Regional Mohamed Tahar El Maamouri
city: Sousse
country: Tunisia
facility: Hopital Universitaire Sahloul
city: Tunis Jebbari
country: Tunisia
facility: Hospital La Rabta
city: Tunis
country: Tunisia
facility: Hopital Habib Thameur
city: Tunis
country: Tunisia
facility: Military Hospital of Instruction of Tunis
city: Ankara
country: Turkey
facility: Hacettepe University Medical Faculty
city: Ankara
country: Turkey
facility: Gulhane Egitim ve Arastirma Hastanesi
city: Elazig
country: Turkey
facility: Firat University Hospital
city: Hatay
country: Turkey
facility: Mustafa Kemal University Research and Practise Hospital
city: Istanbul
country: Turkey
facility: Acibadem Fulya Hospital
city: Istanbul
country: Turkey
facility: Sisli Etfal Egitim ve Arastirma Hospital
city: Istanbul
country: Turkey
facility: BAU Medical Park Goztepe Hospital
city: Istanbul
country: Turkey
facility: Marmara University Medical Faculty
city: Izmir
country: Turkey
facility: Dokuz Eylul University Medical Faculty
city: Kharkiv
country: Ukraine
facility: MNCE City Clinical Hospital No 2 named after prof O O Shalimov of the Kharkiv City Council
city: Kharkiv
country: Ukraine
facility: SE 'National institute therapy named L.T. Maloi NAMS of Ukraine'
city: Kherson
country: Ukraine
facility: KZ Khersonska Miska Klinichna Likarnia Im. Ye.Ie.Karabelesha
city: Kyiv
country: Ukraine
facility: KNP Kyivska miska klinichna likarnia №18 vykonavchoho orhanu KMR (KMDA)
city: Kyiv
country: Ukraine
facility: LLC Treatment and Diagnostic Center Adonis Plus
city: Kyiv
country: Ukraine
facility: Medical Research and Practice Center Medbud of the Public Joint Stock Holding Company Kyivmiskbud
city: Kyiv
country: Ukraine
facility: Kyiv Railway Clinical Hospital #2 Of Branch 'Health Center' Of The Company 'Ukrainian Railway'
city: Kyiv
country: Ukraine
facility: Kyiv Regional Clinical Hospital
city: Odesa
country: Ukraine
facility: Odeska oblasna klinichna likarnia
city: Ternopil
country: Ukraine
facility: Ternopil municipal hospital #1
city: Uzhgorod
country: Ukraine
facility: MNCE Zakarpatska Regional Clinical Hospital named after A Novak of Zakarpatska Regional Council
city: Vinnytsia
country: Ukraine
facility: Health Clinic Limited Liability Company
city: Zaporozhye
country: Ukraine
facility: KU 6 miska klinichna likarnia ZMR
city: Barnsley
country: United Kingdom
facility: Barnsley District General Hospital
city: Cambridge
country: United Kingdom
facility: Addenbrooke's Hospital
city: London
country: United Kingdom
facility: St George's Healthcare NHS Trust
Study officials:
affiliation: Janssen Research & Development, LLC
name: Janssen Research & Development, LLC Clinical Trial
role: STUDY_DIRECTOR
References:
citation: Sandborn WJ, D'Haens GR, Reinisch W, Panes J, Chan D, Gonzalez S, Weisel K, Germinaro M, Frustaci ME, Yang Z, Adedokun OJ, Han C, Panaccione R, Hisamatsu T, Danese S, Rubin DT, Sands BE, Afzali A, Andrews JM, Feagan BG; GALAXI-1 Investigators. Guselkumab for the Treatment of Crohn's Disease: Induction Results From the Phase 2 GALAXI-1 Study. Gastroenterology. 2022 May;162(6):1650-1664.e8. doi: 10.1053/j.gastro.2022.01.047. Epub 2022 Feb 5.