Clinical trial NCT00545883: Impact of GERD on Daily Life (NIS)
Official title: An Epidemiological, Observational Study to Describe Symptom Control and Impact on Daily Life of GERD in Patients With Erosive Gastroesophageal Reflux Disease.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: GERD
Keywords: GERD
esophagitis
PPI
Lead sponsor: AstraZeneca
Sponsor class: INDUSTRY
First posted: 2007-10-17
Enrollment: 2001
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Primary \& Specialty care units

Brief summary: The aim of this study is to gather epidemiological data in a population of GERD patients in primary care with a history of erosive esophagitis (less than or equal to 3 years).


Eligibility criteria: Inclusion Criteria:

* Patients with erosive esophagitis (endoscopical findings according to the Los Angeles Classification; grade A-D) currently not treated with a proton pump inhibitor, for whom the general practitioner (GP) has decided to initiate or change the treatment for GERD

Primary outcomes:
measure: To gather epidemiological data in a population of GERD patients
timeFrame: After collection of all questionnaires
Secondary outcomes:
measure: To evaluate the added value of a new patient questionnaire (GERD Impact Scale) as a useful tool for the initial and long-term management of GERD patients: determination of the appropriate treatment and evaluation of the response to treatment.
timeFrame: After collection of all questionnaires
Other outcomes:
Locations:
city: Aarschot
country: Belgium
facility: Research Site
city: Aartselaar
country: Belgium
facility: Research Site
city: Alken
country: Belgium
facility: Research Site
city: Angleur
country: Belgium
facility: Research Site
city: Antwerpen
country: Belgium
facility: Research Site
city: Balen
country: Belgium
facility: Research Site
city: Berchem
country: Belgium
facility: Research Site
city: Beringen
country: Belgium
facility: Research Site
city: Beyne-Heusay
country: Belgium
facility: Research Site
city: Boechout
country: Belgium
facility: Research Site
city: Boirs
country: Belgium
facility: Research Site
city: Boom
country: Belgium
facility: Research Site
city: Borgerhout
country: Belgium
facility: Research Site
city: Bornem
country: Belgium
facility: Research Site
city: Bruxelles
country: Belgium
facility: Research Site
city: Chenee
country: Belgium
facility: Research Site
city: Court-Saint-Etienne
country: Belgium
facility: Research Site
city: Deurne
country: Belgium
facility: Research Site
city: Diegem
country: Belgium
facility: Research Site
city: Diest
country: Belgium
facility: Research Site
city: Dilbeek
country: Belgium
facility: Research Site
city: Duffel
country: Belgium
facility: Research Site
city: Eindhout
country: Belgium
facility: Research Site
city: Ekeren
country: Belgium
facility: Research Site
city: Essen
country: Belgium
facility: Research Site
city: Flemalle
country: Belgium
facility: Research Site
city: Fleron
country: Belgium
facility: Research Site
city: Geel
country: Belgium
facility: Research Site
city: Genk
country: Belgium
facility: Research Site
city: Gooik
country: Belgium
facility: Research Site
city: Grace-Hollogne
country: Belgium
facility: Research Site
city: Grand-Rechain
country: Belgium
facility: Research Site
city: Grivegnee
country: Belgium
facility: Research Site
city: Grobbendonk
country: Belgium
facility: Research Site
city: Groot-Biigaarden
country: Belgium
facility: Research Site
city: Halen
country: Belgium
facility: Research Site
city: Hannut
country: Belgium
facility: Research Site
city: Herentals
country: Belgium
facility: Research Site
city: Herenthout
country: Belgium
facility: Research Site
city: Hermalle-sous-Huy
country: Belgium
facility: Research Site
city: Herselt
country: Belgium
facility: Research Site
city: Herstal
country: Belgium
facility: Research Site
city: Herve
country: Belgium
facility: Research Site
city: Heusden-Zolder
country: Belgium
facility: Research Site
city: Hoboken
country: Belgium
facility: Research Site
city: Hoeilaart
country: Belgium
facility: Research Site
city: Houthalen-Helchteren
country: Belgium
facility: Research Site
city: Huy
country: Belgium
facility: Research Site
city: Itegem
country: Belgium
facility: Research Site
city: Ivoz-Ramet
country: Belgium
facility: Research Site
city: Jodoigne
country: Belgium
facility: Research Site
city: Keerbergen
country: Belgium
facility: Research Site
city: Kortrijk-Dutsel
country: Belgium
facility: Research Site
city: Landen
country: Belgium
facility: Research Site
city: Lasne
country: Belgium
facility: Research Site
city: Leefdaal
country: Belgium
facility: Research Site
city: Leopoldsburg
country: Belgium
facility: Research Site
city: Liederkerke
country: Belgium
facility: Research Site
city: Liege
country: Belgium
facility: Research Site
city: Lier
country: Belgium
facility: Research Site
city: Lommel
country: Belgium
facility: Research Site
city: Londerzeel
country: Belgium
facility: Research Site
city: Louveigne
country: Belgium
facility: Research Site
city: Maasmechelen
country: Belgium
facility: Research Site
city: Mechelen
country: Belgium
facility: Research Site
city: Merksem
country: Belgium
facility: Research Site
city: Munsterbilzen
country: Belgium
facility: Research Site
city: Niel
country: Belgium
facility: Research Site
city: Noordewijk
country: Belgium
facility: Research Site
city: Olen
country: Belgium
facility: Research Site
city: Oostmalle
country: Belgium
facility: Research Site
city: Overpelt
country: Belgium
facility: Research Site
city: Paal-Beringen
country: Belgium
facility: Research Site
city: Pellaines
country: Belgium
facility: Research Site
city: Peutie
country: Belgium
facility: Research Site
city: Pulle
country: Belgium
facility: Research Site
city: Putte
country: Belgium
facility: Research Site
city: Puurs
country: Belgium
facility: Research Site
city: Reet
country: Belgium
facility: Research Site
city: Retie
country: Belgium
facility: Research Site
city: Retinne
country: Belgium
facility: Research Site
city: Riemst
country: Belgium
facility: Research Site
city: Rijkhoven
country: Belgium
facility: Research Site
city: Rixensart
country: Belgium
facility: Research Site
city: Roosdaal
country: Belgium
facility: Research Site
city: Schelle
country: Belgium
facility: Research Site
city: Schilde
country: Belgium
facility: Research Site
city: Schulen-herk-de-stad
country: Belgium
facility: Research Site
city: Seraing
country: Belgium
facility: Research Site
city: Spouwen
country: Belgium
facility: Research Site
city: Stabroek
country: Belgium
facility: Research Site
city: Steenokkerzeel
country: Belgium
facility: Research Site
city: Ternat
country: Belgium
facility: Research Site
city: Tessenderlo
country: Belgium
facility: Research Site
city: Tienen
country: Belgium
facility: Research Site
city: Tollembeek
country: Belgium
facility: Research Site
city: Tongeren
country: Belgium
facility: Research Site
city: Vierset-Barse
country: Belgium
facility: Research Site
city: Viller-le-Temple
country: Belgium
facility: Research Site
city: Vilvoorde
country: Belgium
facility: Research Site
city: Walem
country: Belgium
facility: Research Site
city: Wambeek
country: Belgium
facility: Research Site
city: Weerde
country: Belgium
facility: Research Site
city: Wespelaar
country: Belgium
facility: Research Site
city: Westerlo
country: Belgium
facility: Research Site
city: Westmeerbeek
country: Belgium
facility: Research Site
city: Willebroek
country: Belgium
facility: Research Site
city: Wilrijk
country: Belgium
facility: Research Site
city: Wolvertem
country: Belgium
facility: Research Site
city: Zandhoven
country: Belgium
facility: Research Site
city: Zemst
country: Belgium
facility: Research Site
city: Zichem
country: Belgium
facility: Research Site
Study officials:
affiliation: ULG
name: E. Louis, PR
role: PRINCIPAL_INVESTIGATOR
References: