Clinical trial NCT06344598: Identification and Assessment of Risk Factors for the Development of Osteoporosis in Adults and Children Living in the Abay Region of the Republic of Kazakhstan Using the Method of Dual-energy X-ray Absorptiometry and Clinical and Epidemiological Research
Official title: Clinical and Epidemiological Risk Evaluation of Osteoporosis Prevalence at Different Ages With to Assess Bone Quantification Using Dual-energy X-ray Absorptiometry
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Improving the Early Diagnosis of Osteoporosis in Adults and Children Living in the Abay Region of Kazakhstan
Keywords: osteoporosis, dual-energy X-ray absorptiometry, bone mineral density, risk factors
Lead sponsor: Semey State Medical University
Sponsor class: OTHER
Collaborators: name: Ministry of Science and Higher Education of the Republic of Kazakhstan
First posted: 2024-04-03
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Residents of the Abay region of the Republic of Kazakhstan

Brief summary: A survey of people to identify risk factors for osteoporosis, which include age, gender, lifestyle, diet, physical activity, the presence or absence of somatic pathology. Diagnosis of osteoporosis by dual-energy X-ray absorptiometry. Conducting a correlation analysis of the relationship of the data obtained.

Detailed description: Successful diagnosis of osteoporosis is possible with the complex use of clinical, laboratory and radiological methods. In the complex of diagnostic methods, a special place has given to dual-energy X-ray absorptiometry, which is the "gold standard". The research area contains the following tasks:

Risk factors for the development of osteoporosis will be identified and quantified in the formed study groups of adults; to determine the diagnostic value of the risk factors for the development of osteoporosis obtained during the examination.

to assess the state of BMD in adults using X-ray absorptiometry (DXA) To carry out a correlation analysis of the relationship between the obtained data in adults of the Abay region of of the Republic of Kazakhstan

Eligibility criteria: Inclusion Criteria: adults and children without a history of pathological fractures and congenital pathology of the musculoskeletal system.

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Exclusion Criteria: adults and children with congenital pathology of the musculoskeletal system

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Primary outcomes:
measure: Risk factors for the development of osteoporosis will be identified and quantified in the formed study groups of adults
timeFrame: By the end of Dec 2025
measure: to determine the diagnostic value of the risk factors for the development of osteoporosis obtained during the examination
timeFrame: By the end of Dec 2025
measure: to assess the state of BMD in adults using X-ray absorptiometry (DXA)
timeFrame: By the end of Dec 2025
measure: To carry out a correlation analysis of the relationship between the obtained data in adults of the Abay region of of the Republic of Kazakhstan
timeFrame: By the end of Dec 2025
Secondary outcomes:
Other outcomes:
Locations:
city: Semey
country: Kazakhstan
facility: Semey Medical University
Study officials:
References: