Clinical trial NCT03833505: Enterobius Vermicularis and Bruxism in Children
Official title: Evaluation of Relationship Between Enterobius Vermicularis Infection and Bruxism in Children
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Bruxism, Sleep
Lead sponsor: Aydin Adnan Menderes University
Sponsor class: OTHER
First posted: 2019-02-07
Enrollment: 26
Sex: ALL
Minimum age (years): 3
Maximum age (years): 10
Standard ages: CHILD
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: The study included E. vermicularis-positive (Group 1, n =13) and E. vermicularis-negative (Group 2: n = 13) children aged between 3-10 years, who were admitted to Aydın Adnan Menderes University Faculty of Medicine Paediatric Gastroenterology Clinic.

Brief summary: Background. Bruxism is an involuntary, non-functional activity of the masticatory system, and is frequently seen in childhood. Bruxism has many aetiologies, like malocclusion, psychological factors, allergies and gastrointestinal disorders.

Aim. To investigate the relationship between Enterobius vermicularis infection and bruxism in children.

Detailed description: Bruxism has many aetiologies, like occlusal interferences, malocclusion, malnutrition, psychological factors, allergies and gastrointestinal disorders. Among these gastrointestinal disorders, are various intestinal parasitic infections.

Given the controversy surrounding the potential association between bruxism and intestinal parasitic infestations, both important health issues, this study sought to evaluate the relationship between E. vermicularis infection and bruxism in E. vermicularis-positive and E. vermicularis-negative 3-10-year-olds children with bruxism.

Eligibility criteria: Inclusion Criteria:

* Teeth-grinding at least once a week in the last 3 months before recruitment according to the criteria established by the American Academy of Sleep Medicine (AASM)
* Angle class I occlusion
* Mesial step occlusion according to flush terminal plane.

Exclusion Criteria:

* Treated with anti-helminthic drugs in the last 2 months before recruitment
* Drugs used that could affect the central nervous system and prevent sleep (sedatives, anti-depressants, neuroleptics, anti-muscarinics, selective serotonin re-uptake inhibitors)
* Sleep disorders (snoring, insomnia, obstructive sleep apnoea, restless leg syndrome, sleep-related epilepsy)
* Psychiatric or neurological disorders
* Upper respiratory system obstruction (last 15 days),
* Any systemic disease;
* Teeth erosion due to internal (reflux) or external (acidic drinks) factors
* Dermatological problems, associated with the use of BiteStrip (Up2dent, Inc., Pulheim, Germany);
* Unsuitable skin structure;
* Previously diagnosed and treated for bruxism;
* Angle class II or class III occlusion

Primary outcomes:
measure: Survey
timeFrame: 24.03.2017-20.05.2018
Secondary outcomes:
measure: Oral examination
timeFrame: 24.03.2017-20.05.2018
Other outcomes:
measure: BiteStrip
timeFrame: 24.03.2017-20.05.2018
Locations:
city: Aydın
country: Turkey
facility: Adnan Menderes University, Faculty of Dentistry, Department of Pediatric Dentistry
Study officials:
affiliation: ADU Faculty of Dentistry Paediatric Dentistry Department
name: K. Görkem Ulu Güzel
role: STUDY_DIRECTOR
References:
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