Clinical trial NCT02082561: False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment for Anxiety Disorders
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Panic Disorder
Generalized Anxiety Disorder
Social Anxiety Disorder
Keywords: transdiagnostic treatment
cognitive behavior therapy
anxiety
panic disorder
generalized anxiety disorder
social anxiety disorder
Lead sponsor: Florida State University
Sponsor class: OTHER
First posted: 2014-03-10
Enrollment: 28
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the current study was to test the efficacy of an individually administered, brief (5-session) transdiagnostic treatment for anxiety disorders. The current treatment (called F-SET) focuses chiefly on the elimination of anxiety maintaining behaviors and cognitive strategies (so-called "safety" aids) among individuals suffering from a range of anxiety disorders including generalized anxiety disorder (GAD), social anxiety disorder (SAD) and panic disorder (PD). We hypothesized that the F-SET protocol would produce better overall outcome relative to a waitlist control.

Detailed description: The aim of the current study was to test the efficacy of an individually administered, brief (5-session) transdiagnostic treatment for anxiety disorders. The current treatment (called F-SET) focuses chiefly on the elimination of anxiety maintaining behaviors and cognitive strategies (so-called "safety" aids) among individuals suffering from a range of anxiety disorders including generalized anxiety disorder (GAD), social anxiety disorder (SAD) and panic disorder (PD).

Four primary hypotheses were evaluated in the current study: (1) the F-SET protocol would produce better overall outcome relative to a waitlist control, (2) the F-SET protocol would yield clinically significant improvement of primary diagnosis symptoms as well as secondary diagnosis symptoms, (3) the F-SET protocol would create treatment improvement that is maintained during a 1 month follow-up interval and (4) given that reduction of safety aid use is the key mechanism of change in the F-SET treatment, a reduction in safety aid use will mediate the relationship between pre and post treatment.

Eligibility criteria: Inclusion Criteria:

* Participants must have a primary diagnosis of panic disorder, generalized anxiety disorder, or social anxiety disorder.
* No change in medication type or dose during the 12 weeks prior to treatment

Exclusion Criteria:

* Current or past schizophrenia, bipolar disorder, or organic mental disorder

Primary outcomes:
measure: The Structured Clinical Interview for the DSM-IV
timeFrame: One Month Follow-up
measure: Clinician Global Impressions Scale (CGI) - Severity of Illness Subscale
timeFrame: One Month Follow-up
measure: Work and Social Adjustment Scale (WSAS)
timeFrame: One Month Follow-up
Secondary outcomes:
Other outcomes:
Locations:
city: Tallahassee
country: United States
facility: Florida State University
state: Florida
Study officials:
affiliation: Florida State University
name: Norman B Schmidt, Ph.D
role: PRINCIPAL_INVESTIGATOR
References: