louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT04030377: Postop Catheterization for Urinary Retention
Official title: Treatment of Postoperative Urinary Retention - WHAT DO WOMEN WANT?
Study type: OBSERVATIONAL
Overall status: TERMINATED
Conditions: Urinary Retention
Lead sponsor: Endeavor Health
Sponsor class: OTHER
First posted: 2019-07-24
Enrollment: 47
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult women presenting to the urogynecology offices at NorthShore University HealthSystem with a urogynecologic diagnosis desiring surgical management.

Brief summary: This study investigates patient's preference and satisfaction with choice of catheterization after surgical urogynecological procedures.

Detailed description: Preoperatively, the enrolled patient receives information about risks and benefits of three ways of bladder catheterization as means of management of postoperative urinary retention. Based on this information, the patient chooses her preferred way of postoperative catheterization in case she experiences acute urinary retention after surgery. After the surgery, those patients requiring catheterization postoperatively evaluate their experience in a postoperative questionnaire.

Eligibility criteria: Inclusion Criteria:

* All female patients who undergo urogynecological surgery procedures at NorthShore University HealthSystem and consent to participate

Exclusion Criteria:

* Patients who cannot read, comprehend, and write in English

Primary outcomes:
measure: Patient satisfaction with choice of catheterization method
timeFrame: 2 weeks after index procedure
Secondary outcomes:
measure: Assessment of complication rates
timeFrame: 2 weeks after index procedure
Other outcomes:
Locations:
city: Skokie
country: United States
facility: NorthShore University HealthSystem
state: Illinois
Study officials:
affiliation: Endeavor Health
name: Sylvia M Botros, MD
role: STUDY_DIRECTOR
References:
Clinical trial NCT03408977: Meal Enjoyment and Tolerance: Sex Differences
Official title: Factors That Determine the Responses to Meal Ingestion: Sex Differences
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: meal ingestion
meal tolerance
postprandial responses
hedonic sensations
homeostatic sensations
Lead sponsor: Hospital Universitari Vall d'Hebron Research Institute
Sponsor class: OTHER
First posted: 2018-01-24
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Aim: to determine the effect of gender on the responses to meal ingestion. Participants (10 men and 10 women) will be instructed to eat a standard dinner the day before, to consume a standard breakfast at home after overnight fast, and to report to the laboratory, where the test meal will be administered 4 h after breakfast. Studies will be conducted in a quiet, isolated room with participants sitting on a chair. Participants will ingest a probe meal up to the level of maximal satiation. The probe meal will be served stepwise (150 Kcal every 5 min). Perception of homeostatic (hunger/satiation, fullness) and hedonic (digestive well-being, mood) sensations will be measured at 5 min intervals 10 min before, during and 20 min after ingestion at 10 min intervals.


Eligibility criteria: Inclusion Criteria:

* non-obese

Exclusion Criteria:

* history of gastrointestinal symptoms
* prior obesity
* use of medications
* history of anosmia and ageusia
* current dieting
* alcohol abuse
* psychological disorders
* eating disorders

Primary outcomes:
measure: Meal tolerance
timeFrame: 100 min
Secondary outcomes:
measure: Change in digestive well-being induced by the probe meal
timeFrame: 1 day
measure: Change in fullness sensation induced by the probe meal
timeFrame: 1 day
measure: Change in mood induced by the probe meal
timeFrame: 1 day
measure: Change in abdominal discomfort induced by the probe meal
timeFrame: 1 day
measure: Change in hunger/satiety induced by the probe meal
timeFrame: 1 day
Other outcomes:
Locations:
city: Barcelona
country: Spain
facility: University Hospital Vall d'Hebron
Study officials:
References:
Clinical trial NCT03479177: Home-Based High Intensity Interval Training Intervention for Low Active Adults
Official title: The Effect of a Home-Based High Intensity Interval Training Intervention on Increasing Exercise Among Low Active Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cardiovascular Diseases
Lead sponsor: University of Minnesota
Sponsor class: OTHER
First posted: 2018-03-27
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purpose of this study is to examine the effect of a home-based high intensity interval training intervention on exercise among low active adults (defined as engaging in exercise 90 minutes or less per week). Participants will be randomly assigned to a HIIT-based intervention or a wait-list control each lasting 12 weeks (participants in the wait-list control condition will have the option of receiving the HIIT intervention following the 12 weeks).

Detailed description: The intervention will be a 12-week high intensity interval training workout that will consist of home-based exercise sessions prescribed by the exercise counselor. The exercise sessions will be based on exercises the participant can confidentially engage in (regular push-ups vs. knee push-ups vs. wall push-ups). The goal will be to engage in three exercise sessions per week. The participants will receive weekly telephone calls during the first month and bi-weekly calls during months 2 and 3. The exercise counselor will also engage in dialogue that will motivate the participant to exercise.

Eligibility criteria: Inclusion Criteria:

* 18 and older
* Exercising for 90 minutes or less each week
* Access to the Internet

Exclusion Criteria:

* A history of coronary heart disease (history of myocardial infarction, symptoms of angina)
* Orthopedic problems that would limit physical activity participation
* Diabetes
* Stroke
* Osteoarthritis
* Any other medical condition that may make physical activity unsafe or unwise.
* Current or planned pregnancy
* Psychosis or current suicidal ideation
* Psychiatric hospitalization within the last six months

Primary outcomes:
measure: Exercise minutes per week
timeFrame: Change from Baseline to 12 weeks
Secondary outcomes:
measure: Biometrics
timeFrame: Change from Baseline to 12 weeks
measure: Social Support for Exercise Questionnaire
timeFrame: Change from Baseline to 12 weeks
measure: Physical Activity Self-efficacy Questionnaire
timeFrame: Change from Baseline to 12 weeks
measure: Physical Activity Enjoyment Scale (PACES)
timeFrame: Change from Baseline to 12 weeks
measure: Outcome Expectancies Questionnaire
timeFrame: Change from Baseline to 12 weeks
Other outcomes:
Locations:
city: Minneapolis
country: United States
facility: University of Minnesota- Twin Cities
state: Minnesota
Study officials:
affiliation: University of Minnesota
name: Beth Lewis, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00192777: Concurrent Xeloda and Radiotherapy for Bone Metastases
Official title: Concurrent Xeloda and Radiotherapy for Bone Metastases
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE2
Conditions: Solid Tumors
Bone Metastases
Keywords: Solid Tumors
Bone Metastases
Radiotherapy
Xeloda
Concurrent
Radiosensitization
Lead sponsor: Rambam Health Care Campus
Sponsor class: OTHER
First posted: 2005-09-19
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Hypothesis: Radiosensitization using Xeloda should improve the rate of complete pain relief.

Primary Objective:

* To determine the frequency of pain relief for the proposed regimen.

Secondary Objective(s):

* To determine the duration of pain relief and narcotic relief for the proposed regimen.
* To determine the frequency of narcotic relief for the proposed regimen.
* To determine the toxicity of concurrent UFT and radiotherapy in patients with bone metastases.


Eligibility criteria: Inclusion Criteria:

1. The patient must be 18 years of age or older.
2. The patient must have epithelial malignancy.
3. Radiographic evidence of bone metastasis is required. Acceptable studies include plain radiographs, radionuclide bone scans, computed tomography scans and magnetic resonance imaging.
4. The patient must have pain that appears to be related to the radiographically documented metastasis.
5. Patients must have an estimated life expectancy of 3 months or greater.
6. Signed study-specific informed consent.
7. Karnofsky performance status  40.
8. Calculated creatinine clearance \> 50 ml/min

Primary outcomes:
measure: The frequency of pain relief for the proposed regimen, using a scale that takes into account the subjective feeling and the use of analgesics
timeFrame: after 3 months
Secondary outcomes:
measure: The duration of pain relief and narcotic relief for the proposed regimen after one year
measure: The frequency of narcotic relief for the proposed regimen after one year
measure: The toxicity of concurrent UFT and radiotherapy in patients with bone metastases after one year
Other outcomes:
Locations:
city: Haifa
country: Israel
facility: Rambam Health Care Campus
Study officials:
affiliation: Dept. of Oncology, Rambam Health Care Campus
name: Kuten Abraham, Prof.
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03499977: Acute Cycling on Executive Control
Official title: The Effects of Acute Cycling on Executive Control
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Physical Activity
Keywords: Physical Activity
Executive function
Anti-saccade
Lead sponsor: Western University, Canada
Sponsor class: OTHER
First posted: 2018-04-17
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: This study will examine whether 10-minute bouts of cycling at various intensities will impact executive functioning (i.e., cognitive ability) as assessed by the antisaccade (AS) task through a total of five visits. An antisaccade is a rapid eye movement away from a visual target. The ability to suppress making an eye movement towards a visual target gauges inhibitory control (i.e., a domain of executive functioning). In the initial visit, participants' exercise capacity will be assessed through a maximal effort cycling test. Intensities for the cycling bouts (i.e., high, moderate, low) in subsequent sessions will be based upon this maximal effort cycling test. In visits 2 through 5, participants will complete an AS task, followed by a 10-minute bout of cycling, and then complete the AS task again. The order of cycling intensities will be randomized between participants. Differences in the AS task (i.e., reaction time and accuracy) will be compared between and within cycling conditions.


Eligibility criteria: Inclusion Criteria:

* Able to read, write and understand English
* Full time student enrolled at Western University
* Able to perform a ten-minute exercise task at a light intensity without health implications
* Have email or phone number for contacting purposes

Exclusion Criteria:

* Do not have a medical condition that prevents you from exercise (e.g. heart attack in the past year, heart disease, irregular heartbeat, etc.)
* Do not have history of eye injury or neurological impairment
* Do not have an orthopaedic limitation
* Are not pregnant

Primary outcomes:
measure: Reaction Time
timeFrame: 30 minutes
measure: Accuracy
timeFrame: 30 minutes
Secondary outcomes:
Other outcomes:
measure: Heart Rate
timeFrame: 10 minutes
Locations:
city: London
country: Canada
facility: Western University
state: Ontario
Study officials:
affiliation: Western University
name: Harry Prapavessis, Ph.D
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06417177: Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
Official title: Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: EARLY_PHASE1
Conditions: Aging
Menopause
Hypoxia
Vasodilation
Lead sponsor: University of Missouri-Columbia
Sponsor class: OTHER
First posted: 2024-05-16
Enrollment: 75
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.


Eligibility criteria: Inclusion Criteria:

* Female assigned at birth
* Pre, peri- or post-menopausal
* Healthy weight (BMI ≥18 and ≤30 kg/m2)

Exclusion Criteria:

* Male (assigned at birth)
* Pregnancy, breastfeeding
* Use of hormone replacement therapies
* Hysterectomy
* Body mass index \>30 kg/m2
* Diagnosed sleep apnea
* Current smoking/Nicotine/Drug use
* Nerve/neurologic disease
* Cardiovascular, hepatic, renal, respiratory disease
* Blood pressure ≥140/90 mmHg
* Diabetes, Polycystic ovarian syndrome
* Communication barriers
* Prescription medications
* Malignant cancer

Primary outcomes:
measure: Forearm blood flow
timeFrame: Change from baseline to 5 minutes.
Secondary outcomes:
Other outcomes:
Locations:
city: Columbia
country: United States
facility: University of Missouri-Columbia
state: Missouri
Study officials:
References:
Clinical trial NCT00365677: A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
Official title: Compare the Safety and Effectiveness of Two Versions of the Bausch & Lomb Zyoptix™ Tissue Saving Aspheric Algorithm to the Current Zyoptix™ Tissue Saving Algorithm When Used for Myopia and Myopic Astigmatism Lasik Treatment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Myopia
Astigmatism
Lead sponsor: Bausch & Lomb Incorporated
Sponsor class: INDUSTRY
First posted: 2006-08-17
Enrollment: 127
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The objective of this study was to compare the safety and effectiveness of two versions of the Bausch \& Lomb Zyoptix Tissue Saving Aspheric Algorithm versus the current Zyoptix Tissue Saving Algorithm when used for myopia and myopic astigmatism LASIK treatment.


Eligibility criteria: Inclusion Criteria:

* Myopia with or without astigmatism.
* Normal Corneal topography
* Willing to have both eyes treated with the laser.

Exclusion Criteria:

* Contraindications to LASIK.

Primary outcomes:
measure: Uncorrected visual acuity
timeFrame: At 90 days post surgery
measure: Preservation of best spectacle corrected high contrast logMAR distance visual acuity compared to baseline.
timeFrame: At 90 days post surgery
Secondary outcomes:
measure: Deviation from target correction
timeFrame: At 90 days post surgery
measure: Improvement in uncorrected distance high contrast logMAR visual acuity compared to baseline
timeFrame: At 90 days post surgery
Other outcomes:
Locations:
Study officials:
affiliation: Bausch & Lomb Incorporated
name: Joanne Egamino, PhD
role: STUDY_DIRECTOR
References:
Clinical trial NCT02041377: Evaluation of an Karajishi TS Investigational Blood Glucose Monitoring System
Official title: User Performance of the Karajishi Contour TS Blood Glucose Monitoring System
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Diabetes
Lead sponsor: Ascensia Diabetes Care
Sponsor class: INDUSTRY
First posted: 2014-01-22
Enrollment: 134
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: The purpose of this study was to determine if subjects who have diabetes can operate the Investigational Blood Glucose Monitoring System (BGMS) with no training and obtain valid glucose results.


Eligibility criteria: Inclusion Criteria:

* Males and females, 18 years of age and older
* People with type 1 or type 2 diabetes
* Able to speak, read, and understand English
* Willing to complete all study procedures

Exclusion Criteria:

* Hemophilia or any other bleeding disorder
* Pregnancy
* Physical, visual, or neurological impairments that would make the person unable to perform testing with the BGM
* Previously participated in a BG monitor study using the Karajishi TS BGMS (or used a Bayer Contour TS meter)
* Working for a medical laboratory, hospital, or other clinical setting that involves training on and clinical use of blood glucose monitors
* Working for a competitive medical device company, or having an immediate family member who works for such a company
* A condition which, in the opinion of the investigator or designee, would put the person or study conduct at risk

Primary outcomes:
measure: Number of Self-Test Fingerstick Blood Glucose (BG) Results Within +/- 15 mg/dL (<100 mg/dL) and Within +/- 15% (>=100 mg/dL) of Laboratory Glucose Method
timeFrame: 1 hour
Secondary outcomes:
measure: Number of Venous Blood Glucose (BG) Results Within +/- 15 mg/dL (<100 mg/dL) and Within +/- 15% (>=100 mg/dL) of Laboratory Glucose Method
timeFrame: 1 hour
measure: Number of Blood Glucose (BG) Results From Alternative Site Testing (AST) Palm Blood Within +/- 15 mg/dL (<100 mg/dL) and Within +/- 15% (>=100 mg/dL) of Laboratory Glucose Method
timeFrame: 1 hour
measure: Number of Subject Fingerstick Blood Glucose (BG) Results Within +/- 15 mg/dL (<100 mg/dL) and Within +/- 15% (>=100 mg/dL) of Laboratory Glucose Method When Obtained and Tested by Study Staff
timeFrame: 1 hour
measure: Number of Subject Responses That Strongly Agree or Agree or Are Neutral With Questionnaire Statements
timeFrame: 1 hour
Other outcomes:
Locations:
city: Escondido
country: United States
facility: AMCR Institute
state: California
city: Renton
country: United States
facility: Rainier Clinical Research Center
state: Washington
Study officials:
affiliation: Rainier Clinical Research Center
name: Leslie J Klaff, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: AMCR Institute
name: Timothy Bailey, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03546777: Evaluation Coroacromial Ligament Thickness
Official title: Should the Coroacromial Ligament be Evaluated in Shoulder Magnetic Resonance Imaging?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Shoulder Pain
Keywords: Shoulder pain, coracoacromial ligament thickness
Lead sponsor: Suleyman Demirel University
Sponsor class: OTHER
First posted: 2018-06-06
Enrollment: 253
Sex: ALL
Minimum age (years): 15
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients with shoulder pain

Brief summary: In this study, it was aimed to determine the relationship between pathologic findings and coracoacromial ligament thickness in magnetic resonance imaging in shoulder pain patients.

Detailed description: The coracoacromial ligament, which is part of the coracoacromial arch, plays an important role in shoulder biomechanics, joint stability and proprioception. Age-related changes due to chronic stress and cellular impairment may contribute to thickening and stiffening of the coracoacromial ligament to rupture the rotator cuff and development of shoulder pathologies such as impingement syndrome. In this study, it was aimed to determine the relationship between pathologic findings and coracoacromial ligament thickness in magnetic resonance imaging in shoulder pain patients. Secondary purpose is whether the thickness of the coracoacromial ligament is indicative of shoulder pathologies.

Eligibility criteria: Inclusion Criteria:

* Patients aged over 15 years diagnosed with shoulder pain

Exclusion Criteria:

* Sensation and reflexes loss in the upper extremity
* Limitation in passive shoulder movements on physical examination
* Systemic rheumatic disease
* Diabetes mellitus
* Malignant disease
* Active infection
* Intraarticular injection
* Trauma
* History of surgery

Primary outcomes:
measure: Thickness of coracoacromial ligament
timeFrame: 1 week
Secondary outcomes:
Other outcomes:
Locations:
city: Isparta
country: Turkey
facility: Suleyman Demirel University
state: Province
Study officials:
affiliation: Suleyman Demirel University
name: Çiğdem Aydoğan
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06320977: The Influence of Acute Static Stretching on the Ankle Joint-position Sense of Soccer Players
Official title: The Influence of Acute Static Stretching on the Ankle Joint-position Sense of Soccer Players: a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: Static Stretching
Joint Position Sense
Proprioception
Ankle
Soccer
Lead sponsor: University Fernando Pessoa
Sponsor class: OTHER
First posted: 2024-03-20
Enrollment: 19
Sex: MALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The aim of this study isto investigate the influence of acute static stretching on the ankle joint position sense of soccer players.

Detailed description: This crossover randomized controlled trial will include semi-professional soccer players. All participants will perform 3 conditions: two experimental conditions, of static stretching of the gastrocnemius and tibialis anterior muscles, for 30 seconds or 90 seconds; and a control condition (rest). Ankle joint position sense of the dominant limb will be assessed before and immediately after the conditions for the range of 20º of plantar flexion by active repositioning, and using a video camera. Absolute, relative and variable angular errors will be calculated.

Eligibility criteria: Inclusion Criteria:

* male soccer players from the senior level
* aged between 18 and 30 years old
* with normal plantar flexion range of motion
* without history of lower limb injuries in the last 6 months

Exclusion Criteria:

* those with cardiorespiratory, vestibular or neurological diseases
* with bone or joint deformities in the lower limb
* cerebral concussion in the last 3 months
* history of lower limb surgery
* those with positive ankle integrity tests (anterior drawer test, talus tilt test and external rotation stress test)

Primary outcomes:
measure: Absolute angular error
timeFrame: Change from Baseline (Before) to Immediately after interventions or control (After)
measure: Relative angular error
timeFrame: Change from Baseline (Before) to Immediately after interventions or control (After)
measure: Variable angular error
timeFrame: Change from Baseline (Before) to Immediately after interventions or control (After)
Secondary outcomes:
Other outcomes:
Locations:
city: Porto
country: Portugal
facility: Escola Superior de Saúde Fernando Pessoa
Study officials:
affiliation: Escola Superior de Saúde Fernando Pessoa
name: Joana Azevedo, PhD
role: PRINCIPAL_INVESTIGATOR
References: