Clinical trial NCT05182333: Congenital Hand and Upper Extremity Malformations
Official title: A Retrospective Study for Congenital Hand and Upper Extremity Malformations in Assiut University Hospital During the Last Twenty Years
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Congenital Limb Anomaly Nos
Keywords: Congenital upper limb anomalies
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2022-01-10
Enrollment: 100
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All patients with congenital upper limb anomalies

Brief summary: Getting the incidence of upper limb anomalies in our department from 2000 to 2020 and classifying them using IFSSH classification and OMT classification

Detailed description: A retrospective look at the past 20 years illustrated the changes and developments that characterize the world of hand surgery. During these years, old techniques were developed and standardized, new surgical techniques were described, our knowledge improved and illustrated by better classification systems, and new ideas were born that would guide the future of hand surgery. Limb deformities are among the most common birth defects in infants. Over the past 150 years, many classifications of limb abnormalities based on bone morphology and anatomy have been developed.

Congenital anomalies of the hand require consistent and reproducible terminology, and it is a universal language that allows discussion of complex clinical entities, treatment indications and outcome comparisons.

Ideally, the classification of congenital anomalies of the hand will depend on the etiology, giving some indication of the location in the molecular pathway and / or the anatomical location in the developing limb bud where the error occurs and the moment when the fault occurs. The terms should be understandable to geneticists, anatomists, pathologists, and surgeons, and they should allow easy interpretation to parents and, where appropriate, children affected by these conditions. The classification of congenital anomalies of the upper extremity and the important association of these anomalies with systemic disorders and syndromes are described in this study. Depending on the classification, examples are given for each class of anomalies.

Eligibility criteria: Inclusion Criteria:

- All patients with congenital upper limb anomalies in last 20 years in Assiut university hospital.

Exclusion Criteria:

* Conditions that were considered to be difficult to correctly classify because of late presentation, a large span of clinical presentation, extremely rare conditions, and conditions difficult to differentiate from traumatic conditions were excluded (ie, congenital radial head dislocation, congenital tumorous conditions, Marfan syndrome)

Primary outcomes:
measure: Incidences of anomalies
timeFrame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: McCarroll HR. Congenital anomalies: a 25-year overview. J Hand Surg Am. 2000 Nov;25(6):1007-37. doi: 10.1053/jhsu.2000.6457.
citation: Tayel SM, Fawzia MM, Al-Naqeeb NA, Gouda S, Al Awadi SA, Naguib KK. A morpho-etiological description of congenital limb anomalies. Ann Saudi Med. 2005 May-Jun;25(3):219-27. doi: 10.5144/0256-4947.2005.219.