Clinical trial NCT04273971: Acute Effect of Plyometric Exercises on Musculotendinous Properties
Official title: Acute Effect of Plyometric Exercises on Musculotendinous Properties of Quadriceps and Biceps Femoral
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Healthy
Keywords: Adult
Lower extermity
Plyometric exercise
Muscle properties
Lead sponsor: Universidade Federal de Santa Maria
Sponsor class: OTHER
Collaborators: name: Conselho Nacional de Desenvolvimento Científico e Tecnológico
name: Federal University of Rio Grande do Sul
First posted: 2020-02-18
Enrollment: 30
Sex: MALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Single-arm design where all participants receive treatment.
Primary purpose: TREATMENT

Brief summary: Preventive and rehabilitation programs include plyometric exercises to promote agility, power, and muscle activation pattern during jumping. These exercises also are known to cause a high mechanical load that increases the risk of a musculoskeletal injury. The knowledge regarding the musculoskeletal damage result from this configuration of exercise can help to elaborate safer and effective training and rehabilitation programs. In this study, the investigators will conduct a clinical trial to determine the acute effect of plyometric exercises on damage caused on different portions of quadriceps and biceps femoral's muscles and tendons of quadriceps, and biceps femoral, and its effects on mechanical properties.

Detailed description: This is a single-arm clinical trial aiming to determine the acute effect of one session of plyometric exercises on quadriceps and biceps femoral musculotendinous properties in healthy individuals.

The sample size was determined using G\*Power software considering the application of ANOVA: Repeated measures, between factors, 90% power, alpha 0.05. Data from muscle echo intensity of the rectus femoral by Muddle et al. (2019) were considered for this calculation, with an effect size 0.44. A total of 30 individuals was required for this study.

The outcomes will include the muscle and tendon quality, and mechanical properties of the tendon. The assessments will be performed at three different moments: before exercise, immediately after, and 48 hours after exercise.

The data analysis will be performed per protocol. Generalized estimating equations will be used to identify the effects of time followed by Bonferroni posthoc. When effects are found, effect sizes will be estimated. Missing data will be estimated by statistical analysis.

Eligibility criteria: Inclusion Criteria:

* Who practice physical activity (except jump training);
* No previous lower extremity muscle injury at least 6 months before the recruitment;
* No previous lower extremity ligament or tendon injury or surgery;
* No auditory, vestibular, visual or musculoskeletal injuries or disease that limit the execution of the exercise and assessment protocols;
* No hypertension, cardiovascular, or respiratory disease.

Exclusion Criteria:

* Body mass index greater than 30 kg/m².

Primary outcomes:
measure: Change from baseline of echo intensity of quadriceps and biceps femoral muscles
timeFrame: Baseline, immediately after exercise and up to 48 hours exercise
measure: Change from baseline stiffness of patellar tendon
timeFrame: Baseline, immediately after exercise and up to 48 hours exercise
measure: Change from baseline young modulus of patellar tendon
timeFrame: Baseline, immediately after exercise and up to 48 hours exercise
Secondary outcomes:
measure: Change from baseline echo intensity of quadriceps and biceps femoral tendons
timeFrame: Baseline, immediately after exercise and up to 48 hours exercise
Other outcomes:
measure: Change from baseline muscle soreness of quadriceps and biceps femoral muscles
timeFrame: Baseline and up to 48 hours exercise
Locations:
city: Uruguaiana
country: Brazil
facility: Karine Josibel Velasques Stoelben
state: RS
Study officials:
affiliation: Universidade Federal do Pampa
name: Felipe P Carpes, PhD
role: STUDY_DIRECTOR
affiliation: Federal University of Rio Grande do Sul
name: Marco A Vaz, PhD
role: STUDY_CHAIR
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