Clinical trial NCT01920100: Resource Use and Disease Course in Dementia (REDIC)
Official title: Resource Use and Disease Course in Dementia (REDIC)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Neurodegenerative Diseases
Dementia
Keywords: Health Care Costs
Genetic Polymorphism
Lead sponsor: Sykehuset Innlandet HF
Sponsor class: OTHER
Collaborators: name: Norwegian Directorate of Health
name: King's College London
name: Karolinska Institutet
name: Oslo University Hospital
name: University Hospital, Akershus
name: Helse Midt-Norge
name: Norwegian University of Science and Technology
name: University of Bergen
name: Norwegian Centre for Ageing and Health
First posted: 2013-08-09
Enrollment: 696
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Nursing home Memory clinics In-home care Persons without dementia (Control)

Brief summary: This project is based on a three-year program that aims to improve the knowledge of the socioeconomic consequences of dementia in Norway. By including patients with and without dementia in four different cohorts (from nursing homes, from memory clinics, home-dwelling persons with dementia and elderly persons without dementia), the project's aim is to describe the course of dementia, the economical cost of dementia and to look into possible risk factors for dementia.


Eligibility criteria: Memory clinic sample

Inclusion Criteria:

* All patients examined at a memory clinic with mild cognitive impairment or mild dementia

Exclusion Criteria:

* None

In-home care sample

Inclusion Criteria:

* Persons 70 years of age or older receiving in-home care from the municipality

Exclusion Criteria:

* None

Nursing-home sample

Inclusion Criteria:

* All persons admitted to the nursing home with an expected stay of more than four weeks.
* Participants should be 65 years or older, unless established dementia disease, in which case younger persons also will be included

Exclusion Criteria:

* Life expectancy of less than six weeks

Control sample

Inclusion Criteria:

* Persons 65 years or older without any sign of dementia

Exclusion Criteria:

* None

Primary outcomes:
measure: Cost of dementia
timeFrame: 3 years
Secondary outcomes:
measure: The course of neuropsychiatric symptoms
timeFrame: 3 years
measure: Quality of Life in persons admitted to nursing homes
timeFrame: 3 years
measure: Prescription of medication
timeFrame: 3 years
measure: DNA polymorphism
timeFrame: At baseline
measure: Organizational factors of the nursing homes
timeFrame: At baseline
Other outcomes:
Locations:
city: Bergen
country: Norway
facility: University of Bergen
city: Namsos
country: Norway
facility: Senter for omsorgsforskning - Midt
city: Ottestad
country: Norway
facility: Innlandet Hospital Trust
Study officials:
affiliation: Centre for old age psychiatry research, Innlandet Hospital Trust
name: Geir Selbaek, pHd
role: PRINCIPAL_INVESTIGATOR
References:
citation: Callegari E, Saltyte Benth J, Selbaek G, Gronnerod C, Bergh S. Do prescription rates of psychotropic drugs change over three years from nursing home admission? BMC Geriatr. 2021 Sep 16;21(1):496. doi: 10.1186/s12877-021-02437-x.
citation: Sandvik RK, Selbaek G, Bergh S, Aarsland D, Husebo BS. Signs of Imminent Dying and Change in Symptom Intensity During Pharmacological Treatment in Dying Nursing Home Patients: A Prospective Trajectory Study. J Am Med Dir Assoc. 2016 Sep 1;17(9):821-7. doi: 10.1016/j.jamda.2016.05.006. Epub 2016 Jun 16.