Clinical trial NCT05091983: Restrictive Eating Disorders: From Childhood Orality Disorder to Adolescent Dysensoriality
Official title: Restrictive Eating Disorders: From Childhood Orality Disorder to Adolescent Dysensoriality (Orality Dysensoriality and Eating Disorder)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Eating Disorders in Adolescence
Avoidant Restrictive Food Intake Disorder
Keywords: Restrictive eating disorder
anorexia nervosa
Avoidant/Restrictive Food Intake Disorder
sensory modulation disorder
sensory modulation symptoms
sensory over responsivity
sensory integration
Lead sponsor: Assistance Publique - Hôpitaux de Paris
Sponsor class: OTHER
First posted: 2021-10-25
Enrollment: 29
Sex: ALL
Minimum age (years): 12
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The participants were all recruited at the Maison de Solenn, Cochin - Paris, a service specialized in the treatment of eating disorders for adolescents. The participants in the control group are patients followed in this center for another reason than an eating disorder. The participants were recruited in consultation, in day hospital or in complete hospitalization.

Brief summary: This study offers to determine whether adolescent patients with a restrictive eating disorder have variations in their sensoriality compared to a control group.

Detailed description: Eating disorders are a frequent reason for consultation in pediatrics at all ages.

When they are small, children may have an orality disorder. There are multiple potential causes for this disorder: psychogenic, oropraxic but also sensory. The treatment is then adapted to the patient, with, among other things, an orientation towards professionals trained in sensory disorders.

As they grow up, adolescents are particularly at risk of developing eating disorders, which are pathologies that correspond to a biopsychosocial model of understanding that includes psychogenetic, neuroendocrine and immune factors.

Despite major advances in the understanding of this disease, the sensory dimension for these patients is still little studied and is not taken into account in the treatment proposed to adolescents suffering from eating disorders.

Eligibility criteria: Inclusion Criteria:

* Adolescent between 12 to 18 years old.
* Non-opposition of the adolescent and his or her legal guardians collected before the start of the study.
* Patient group: Diagnosis of restrictive eating disorders (Anorexia Nervosa typical or atypical, ARFID) meeting DSM-5 criteria.
* Control group: absence of eating disorders.

Exclusion Criteria:

* Eating disorders secondary to another psychiatric pathology.
* Precarious health status with somatic and/or psychiatric instability that does not allow to answer the questionnaire.
* Language barrier.
* Opposition of the adolescent and/or his/her legal representatives obtained before the start of the study
* Patient under " AME " (medical state help)

Primary outcomes:
measure: Average Sensory Processing Scale Inventory (SPSI) scores between the two groups
timeFrame: Inclusion
Secondary outcomes:
measure: Screening for pathologies known to be associated with a sensory disorder
timeFrame: Inclusion
measure: Screening for pathologies known to be associated with a sensory disorder
timeFrame: Inclusion
measure: Screening for pathologies known to be associated with a sensory disorder
timeFrame: Inclusion
measure: Search for a link between the eating disorders severity and sensory disorders
timeFrame: Inclusion
Other outcomes:
Locations:
city: Paris
country: France
facility: Maison de Solenn Maison des Adolescents, Cochin Hospital
state: IDF
Study officials:
affiliation: APHP - Cochin Hospital
name: Corinne BLANCHET
role: PRINCIPAL_INVESTIGATOR
References:
citation: Battle DE. Diagnostic and Statistical Manual of Mental Disorders (DSM). Codas. 2013;25(2):191-2. doi: 10.1590/s2317-17822013000200017. No abstract available.
citation: Gorwood P, Blanchet-Collet C, Chartrel N, Duclos J, Dechelotte P, Hanachi M, Fetissov S, Godart N, Melchior JC, Ramoz N, Rovere-Jovene C, Tolle V, Viltart O, Epelbaum J. New Insights in Anorexia Nervosa. Front Neurosci. 2016 Jun 29;10:256. doi: 10.3389/fnins.2016.00256. eCollection 2016.
citation: Schoen SA, Miller LJ, Green KE. Pilot study of the Sensory Over-Responsivity Scales: assessment and inventory. Am J Occup Ther. 2008 Jul-Aug;62(4):393-406. doi: 10.5014/ajot.62.4.393.