Clinical trial NCT05054270: Efficacy of Lung Ultrasound in Monitoring Fluid Resuscitation in Chest Trauma Patients
Official title: Efficacy of Lung Ultrasound in Monitoring Fluid Resuscitation in Trauma Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Contusions Pulmonary
Lung Injury
Chest Trauma
Fluid Overload Pulmonary Edema
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2021-09-23
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This is an observational study that will be conducted on patients admitted with chest trauma in Assuit or Alexandria Main University Hospitals after obtaining their or their next of kin consent to participate in the study without affecting their course of treatment according to permission obtained from ethical committee of faculty of medicine in Assiut and Alexandria universities.

Brief summary: Efficacy of Lung ultrasound in monitoring fluid resuscitation in chest trauma patients with lung contusions

Detailed description: Trauma is a public health problem, associated to high morbidity and mortality, In Egypt the mortality from road traffic crashes is about 12000 victims per year.

* Chest trauma represents from 10% to 15% of the total number of traumas worldwide.

According to ATLS protocol , early diagnosis and management of Chest trauma are essential. \*Pulmonary contusion is found in 30-75% of cases of chest injury.

* point of care Ultrasound (POCUS) is Now a corner stone in Emergency management it can predict lung contusions within the first 72 hours after trauma.
* Recently, LUS Play a major role in assessment of the volume status in Trauma patients.
* B-lines score (BLS) has been validated as a lung ultrasound quantification of pulmonary congestion.The sum of all B-lines yields a score, B-lines score (BLS), which assess the degree of lung contusion. So that LUS may provide a valuable safety threshold to conduct fluid therapy.

Eligibility criteria: Inclusion Criteria:

* Age \> 18 years.
* chest trauma patients either with or without other injuries.
* Any patient with either blunt or penetrating chest trauma.

Exclusion Criteria:

* - Patients in cardiac arrest.
* Patient refusal to participate
* Pregnant females.

Primary outcomes:
measure: Number of patients with lung contusion
timeFrame: Upto 24 hours after trauma
Secondary outcomes:
measure: Clinical correlation between Type & volume of Fluid & occurance of pulmonary edema. Correlation between severity of pulmonary lung contusion & The final disposition of the patients whatever (OR _another department _death….. etc) upto 24hr.
timeFrame: For first 24 hours after trauma
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Faculty of medicine Assiut University
Study officials:
References:
citation: Ullman EA, Donley LP, Brady WJ. Pulmonary trauma emergency department evaluation and management. Emerg Med Clin North Am. 2003 May;21(2):291-313. doi: 10.1016/s0733-8627(03)00016-6.
citation: Miller DL, Mansour KA. Blunt traumatic lung injuries. Thorac Surg Clin. 2007 Feb;17(1):57-61, vi. doi: 10.1016/j.thorsurg.2007.03.017.
citation: Cohn SM. Pulmonary contusion: review of the clinical entity. J Trauma. 1997 May;42(5):973-9. doi: 10.1097/00005373-199705000-00033.