Clinical trial NCT05262933: Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
Official title: Effect of Preoperative Coffee Consumption on Intraoperative and Post Operative Outcomes in Cesarean Section With Spinal Anesthesia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hypotension After Spinal Anesthesia
Post-Dural Puncture Headache
Lead sponsor: TC Erciyes University
Sponsor class: OTHER
First posted: 2022-03-02
Enrollment: 2
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: parturient women aged 18-45

Brief summary: The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating conditions. However spinal anesthesia has some complications as hypotension, bradycardia and Post Dural Puncture Headache (PDPH). A practical strategy for avoiding hypotension during initiation of spinal anesthesia for cesarean delivery includes intravenous crystalloid, in conjunction with administration of vasopressors. PDPH is one of the most frequent complications of spinal anesthesia. Conservative therapies such as bed rest, hydration, and caffeine are commonly used as management. For this study, coffee group of patients will be given unsweetened brewed coffee 150 ml until 2-4 hours before surgery. Patients who accept to drink brewed coffee ( coffee group) and water( control group) will be included in the study. The patient's heart rate, blood pressure, oxygen saturation will be monitored and recorded during operation. Intraoperative will be recorded to amount of vasopressor and intraveous crystalloid. Whether the patient develops PDPH in the postoperative period will be followed for 3 days. In addition abdominal auscultation for bowel sounds hourly and the time of first bowel movements will be recorded. According to the patient's statement, the time of first flatulence and defecation will be followed and recorded.


Eligibility criteria: Inclusion Criteria:

* patients who accept to participate in the study
* patient who limit the consumption of caffeinated beverages such as coffee and tea during pregnancy
* Patients with known caffeine or coffee allergy

Exclusion Criteria:

* patients who refuse to participate in the study
* Patients with known cardiovascular disease
* Patients with known cerebrovascular disease
* patients with known neurological, neurodegenerative or psychiatric disease
* patients with known liver failure
* patient followed up with eclampsia and preaclampsi
* higher number of needle passes in spinal anesthesia
* patients treated with an antiemetic

Primary outcomes:
measure: hypotension
timeFrame: intraoperative time period
Secondary outcomes:
measure: Post-dural puncture headache
timeFrame: post operative 3 days
measure: intestinal motility, first flatus
timeFrame: post operative 3 days
Other outcomes:
Locations:
city: Kayseri
country: Turkey
facility: Erciyes University
Study officials:
References: