Clinical trial NCT04716478: Prospective Endodontics Database
Official title: Creation of a Prospective Endodontics Database
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Apical Periodontitis
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2021-01-20
Enrollment: 400
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult patient with apical periodontitis

Brief summary: Endodontic treatment is necessary after certain dental trauma or in the presence of a large carious lesion, associated with signs of irreversible pulpal inflammation. The treatment of apical periodontitis is a real public health issue. The endodontic success rate is between 68 and 85%. Indeed, some studies show that systemic diseases such as diabetes can increase the prevalence and bone loss associated with apical periodontitis. Other studies identify apical periodontitis as a factor that can potentiate symptoms caused by inflammatory diseases such as cardiovascular disease and diabetes by increasing the level of inflammatory cells in the blood.

However, since 2014 the European Society of Endodontology has recommended establishing a higher level of evidence to ensure the link that these pathologies may have. For this, it is necessary to assess the criteria that may influence the healing of apical periodontitis.

Endodata has been developed by dental surgeons specializing in endodontics. The purpose of this software is to improve the clinical follow-up of patients and to establish a clinical and radiological database. In this context, the creation of a clinical database including data for all root canal treatment is of high interest.


Eligibility criteria: Inclusion Criteria:

* Adult patient aged ≥ 18,
* New patients received in consultation by students registered for a Diploma in Endodontics in one of the participating centres (Brest, Bordeaux, Lyon, Nancy, Nantes, Nice, Paris, Toulouse) or received by one of the private practitioners participating in the study;
* Patient with an indication for endodontic treatment or endodontic retreatment on at least one permanent tooth.

Exclusion Criteria:

* Patient unable to understand the purpose and conduct of the study.

Primary outcomes:
measure: The main objective is to build a database with the necessary, relevant and quality data that will allow the development of a diagnostic and therapeutic aid in endodontics.
timeFrame: follow-up at 6 months.
Secondary outcomes:
Other outcomes:
Locations:
city: Bordeaux
country: France
facility: CHU de Bordeaux, Service de Médecine Buccodentaire
city: Brest
country: France
facility: CHU de Brest, Service d'Odontologie
city: Lyon
country: France
facility: Cabinet du Dr Baptiste Rivory
city: Lyon
country: France
facility: Cabinet du Dr Matthieu Durand
city: Lyon
country: France
facility: Cabinet du Dr Oussama Bouamar
city: Lyon
country: France
facility: Cabinet du Dr Paul-Marie Oliva
city: Lyon
country: France
facility: Hospices Civils de Lyon, Service d'Odontologie
city: Lyon
country: France
facility: UFR d'Odontologie, Laboratoire des Multimatériaux et Interfaces
city: Nancy
country: France
facility: CHRU de Nancy, Service d'Odontologie
city: Nantes
country: France
facility: CHU de Nantes, Service d'Odontologie
city: Nice
country: France
facility: Cabinet du Dr Catherine Ricci
city: Paris
country: France
facility: Assistance Publique des Hôpitaux de Paris, Hôpital Bretonneau, Service d'Odontologie
city: Paris
country: France
facility: Assistance Publique des Hôpitaux de Paris, Hôpital Charles Foix, Service d'Odontologie
city: Paris
country: France
facility: Assistance Publique des Hôpitaux de Paris, Hôpital Henri Mondor, Service d'Odontologie
city: Paris
country: France
facility: Assistance Publique des Hôpitaux de Paris, Hôpital Pitié Salpêtrière, Service d'Odontologie
city: Paris
country: France
facility: Cabinet du Dr Cauris Couvrechel
city: Paris
country: France
facility: Cabinet du Dr Francois Bronnec
city: Paris
country: France
facility: Cabinet du Dr Sandrine Dahan
city: Paris
country: France
facility: Cabinet du Dr Valentin Marchi,
city: Toulouse
country: France
facility: CHU de Toulouse, Service d'Odontologie
city: Tours
country: France
facility: Cabinet du Dr Stéphanie Lapon
Study officials:
References: