Clinical trial NCT05129683: Single Session of Anodal Cerebellar vs Cerebral Transcranial Direct Current Stimulation in Stroke Patients
Official title: Effects of a Single Session of Anodal Cerebellar Transcranial Direct Current Stimulation vs Anodal Cerebral Transcranial Direct Current Stimulation on Balance, Mobility and Cognition in Stroke Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: Transcranial Direct Current Stimulation
Anodal Cerebral
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-11-22
Enrollment: 66
Sex: ALL
Minimum age (years): 40
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To compare the effect of anodal cerebellar transcranial direct current stimulation (ctDCS) vs anodal cerebral direct current stimulation on balance, mobility and cognition in stroke patients in stroke patients


Eligibility criteria: Inclusion Criteria:

* ability to give written consent.
* Able to walk unassisted
* Functional status allowing the participants to participate in the balance training.
* Score 6 or above on Johns Hopkins fall risk assessment tool

Exclusion Criteria:

* Neurological diseases, such as Parkinson, Alzheimer
* Any history of psychological illnesses
* Receipt of electrotherapy that might affect the nervous system in the two weeks prior to the study
* Cerebellar disorders
* use of any sedative medicines in the two days prior to the study
* any symptoms of amnesia and depression;
* Memory disorders with scores below 21 on the Mini Mental Status Examination test
* Any signs of severe motor disorders in the lower extremity which cause any movement limitation or deformity
* Any signs of radiculopathy or root lumbar spinal cord involvement
* Any visual or auditory impairment, or vertigo reports
* Use of a heart rate regulator
* Any structural deformities in the lower extremities or the spine
* Any abnormalities in the vestibular system
* History of recent fracture
* Inability to move without assistance

Primary outcomes:
measure: Changes from the base line, Berg balance scale
timeFrame: Immediately after Intervention and then again after 1 hour.
measure: Timed Up and Go test
timeFrame: Immediately after Intervention and then again after 1 hour.
measure: Balance Evaluation Systems Test
timeFrame: Immediately after Intervention and then again after 1 hour.
Secondary outcomes:
measure: Montreal cognitive Scale
timeFrame: 1 hour
measure: tDCS Adverse Effects Questionnaire :
timeFrame: Immediately after Intervention and then again after 1 hour.
measure: 6 min walk test: Distance (meters)
timeFrame: Immediately after Intervention and then again after 1 hour.
measure: Timed 25-Foot Walk test
timeFrame: Immediately after Intervention and then again after 1 hour.
measure: Johns Hopkins fall risk assessment Tool
timeFrame: Immediately after Intervention and then again after 1 hour.
measure: Mini mental state examination (MMSE)
timeFrame: Immediately after Intervention and then again after 1 hour.
Other outcomes:
Locations:
city: Gujrāt
country: Pakistan
facility: Akbar Hospital, Gujrat
state: Punjab
Study officials:
affiliation: Riphah International University
name: Arshad Nawaz Malik, PhD
role: PRINCIPAL_INVESTIGATOR
References: