Clinical trial NCT03300245: Nasal Septum Deviation May Affect Facial Morphologic Parameters.
Official title: The Relationship Between the Direction and Degree of Nasal Septal Deviation and Nasal Bone Morphology
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Nasal Septal Deviation
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2017-10-03
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: patients attending to E N T clinic

Brief summary: The aim of the study is to evaluate the relationship between the direction and degree of nasal septal deviation with nasal bone morphology , along with factors such as age and gender.

Detailed description: The nasal septum is located in the middle of the nasal cavity and it forms the major part of the nose structure. It is divided into a posterior part by the vomer and perpendicular plate of the ethmoid bone and an anterior part by the quadrangular cartilage .

In the growth period, the nasal septum acts as a growth plate that affects surrounding bones and facial skeletal tissues .Thus, nasal septum deviation affects facial morphologic parameters such as interalveolar distance and maxillary rotation distance, causing compensatory changes in the lateral nasal wall and septal deviation,which are associated with nasal floor and palatal region asymmetries .

Nasal septum deviation is the most common anatomic variation in up to 80% of healthy adults .

From the initial growth stages, the maxillary bone and nasal structure have significant anatomic connections because of their close embryologic development.

The severity of septal deviation also affects the ipsilateral lateral lamina of the cribriform plate width and ipsilateral middle turbinate length . Nasal septal deviation may affect nasal bone growth and facial morphology .Knowledge of nasal morphologic parameters plays an important role in planning successful rhinoplasty and septoplasty operations.

Some morphological characteristics of the nose such as bone length and thickness may present different forms according to factors correlated with age, gender, climate and race.

Eligibility criteria: Inclusion Criteria:

* Patients over 18 years old who attending to Ear,Nose and throat department out patients complaining of nasal septum deviation causing nasal symptoms are exposed to maxillofacial CT.

Exclusion Criteria:

1. Patients with a history of rhinoplasty,
2. Patients with cranial and facial trauma or bone deformity (e.g. S-shaped septum deviation).
3. Patients with a mass or polyp in the nasal cavity.
4. Patients with adenoid .
5. Patients with nasopharyngeal lesions.
6. Patients with craniofacial anomalies.

Primary outcomes:
measure: The nasal deviation angle
timeFrame: 10 minutes
measure: The lateral and intermediate nasal bone thickness
timeFrame: 10 minutes
measure: Nasal bone length
timeFrame: 10 minutes
measure: Internasal angle
timeFrame: 10 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Assiut university
Study officials:
affiliation: Assiut University
name: Martina Shawky
role: PRINCIPAL_INVESTIGATOR
References:
citation: Hartman C, Holton N, Miller S, Yokley T, Marshall S, Srinivasan S, Southard T. Nasal Septal Deviation and Facial Skeletal Asymmetries. Anat Rec (Hoboken). 2016 Mar;299(3):295-306. doi: 10.1002/ar.23303. Epub 2016 Jan 22.