Clinical trial NCT05040607: Physical Fitness, Exercise Capacity and Activities of Daily Living in Primary Ciliary Dyskinesia: a Retrospective Study
Official title: Physical Fitness, Exercise Capacity and Activities of Daily Living in Primary Ciliary Dyskinesia: a Retrospective Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Primary Ciliary Dyskinesia
Kartagener Syndrome
Immotile Cilia Syndrome
Keywords: Primary Ciliary Dyskinesia
Kartagener Syndrome
Immotile Cilia Syndrome
Pulmonary Function
Respiratory Muscle Strength
Exercise Capacity
Physical Fitness
Inspiratory Muscle Strength Training
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2021-09-10
Enrollment: 48
Sex: ALL
Minimum age (years): 8
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patient group: PCD patients consulted from Hacettepe University, Faculty of Medicine, Department of Pediatric Chest Diseases, Child Health and Diseases/, Ankara, Turkey to our unit for evaluation in terms of respiratory physiotherapy were included in our study.

Healthy group: Healthy counterparts from our database of the previous studies were included in our study.

Brief summary: Decreased pulmonary function, peripheral muscle strength, and exercise capacity were reported in primary ciliary dyskinesia (PCD) in recent studies. We aimed to investigate the data conducted between 10 July 2015 and 10 January 2015 of pulmonary function, respiratory muscle strength, exercise capacity, physical fitness, and activities of daily living (ADL) in PCD and healthy counterparts retrospectively at the first stage of the study and the effects of inspiratory muscle training on pulmonary function, respiratory muscle strength, and exercise capacity in PCD patients with decreased inspiratory muscle strength from the database recorded between 10 July 2015 and 10 January 2015 retrospectively at the second stage of the study.


Eligibility criteria: Inclusion Criteria:

* Clinically stable
* Being able to cooperate with the assessments
* Not having any orthopedic, or neurological problems

Exclusion Criteria:

* Not being clinically stable
* Not being able to cooperate with the assessments
* Having any orthopedic, or neurological problems

Primary outcomes:
measure: A primer outcome for the first stage of the study: Physical fitness
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: A primer outcome for the second stage of the study: Functional capacity
timeFrame: 10 July 2015-10 January 2015-retrospectively
Secondary outcomes:
measure: Demographic features
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Demographic features
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Demographic features
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Demographic features
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Pulmonary Function
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Respiratory muscle functions
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Exercise Capacity
timeFrame: 10 July 2015-10 January 2015-retrospectively
measure: Activities of Daily Living
timeFrame: 10 July 2015-10 January 2015-retrospectively
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
Study officials:
affiliation: Hacettepe University
name: Hazal Sonbahar Ulu, MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Hacettepe University
name: Deniz Inal Ince, Prof. Dr.
role: STUDY_CHAIR
affiliation: Hacettepe University
name: Deniz Inal Ince, Prof. Dr.
role: STUDY_DIRECTOR
References: