Clinical trial NCT06588842: Cluster Resistance Training and Older Adults
Official title: Cluster Set Resistance Training as a Modality of Power Training in Older Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy Aging
Keywords: Resistance Training
Lead sponsor: University of Miami
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 25
Sex: ALL
Minimum age (years): 55
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This project will focus on improving power in older adults, since power is related to performance of daily activities and memory and decision making. The study will compare cluster set resistance training, where you can rest during a set, to traditional set resistance training where all repetitions in a set must be completed without any between-repetition rest. If cluster set resistance training is better than traditional set resistance training, it could be more beneficial than existing methods in improving independence in older persons.


Eligibility criteria: Inclusion Criteria:

* Montreal Cognitive Assessment Score \> 23
* No memory complaints

Exclusion Criteria:

* Uncontrolled cardiovascular or neuromuscular disease that prevents participation in a training program
* Any systemic inflammatory or autoimmune conditions such as rheumatoid arthritis, system lupus erythematosus, or other serious concomitant medical illness
* Unresolved injury or surgery to the upper or lower limbs.

Primary outcomes:
measure: Change in neuromuscular performance as measured by power production.
timeFrame: Baseline, 12 weeks
measure: Change in neuromuscular performance as measured by 1-repetition maximum (1RM)
timeFrame: Baseline, 12 weeks
Secondary outcomes:
measure: Change in Montreal Cognitive Assessment (MoCA)
timeFrame: Baseline, 12 weeks
measure: Change in the Hopkins Verbal Learning Test
timeFrame: Baseline, 12 weeks
measure: Change in Concept Switching as measured by the Dimensional Card Sort test.
timeFrame: Baseline, 12 weeks
measure: Change in the Flanker test
timeFrame: Baseline, 12 weeks
measure: Change in Event Memory as measured by the Picture Sequence Memory Test
timeFrame: Baseline, 12 weeks
measure: Change in Information Sorting as measured by the NIH List Sorting Test
timeFrame: Baseline, 12 weeks
measure: Change in Reaction Time for a Mental Task as measured by the NIH Pattern Comparison Processing Speed Test
timeFrame: Baseline, 12 weeks
measure: Change in Mental Task as measured by Trail Making Test
timeFrame: Baseline, 12 weeks
measure: Change in the Speed of the Ten-Meter Walk Test
timeFrame: Baseline, 12 weeks
measure: Change in Time for the Five Times Sit-to-Stand Test
timeFrame: Baseline, 12 weeks
measure: Change in Distance of the Seated Medicine Ball Throw
timeFrame: Baseline, 12 weeks
measure: Change in the time required to complete the timed Up-and-Go Test.
timeFrame: Baseline, 12 weeks
measure: Change in Muscle Thickness using Ultrasound
timeFrame: Baseline, 12 weeks
measure: Change in Muscle Quality using Ultrasound
timeFrame: Baseline, 12 weeks
Other outcomes:
Locations:
city: Coral Gables
country: United States
facility: Laboratory of Neruomuscular Research and Active Aging
state: Florida
Study officials:
affiliation: University of Miami
name: Joseph F. Signorile, PhD
role: PRINCIPAL_INVESTIGATOR
References: