Clinical trial NCT01709175: Strength Training Study for Survivors of Breast and Gynecologic Cancer
Official title: The Effect of Resistance Exercise Frequency in Breast and Gynecologic Cancer Survivors
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Breast Cancer
Gynecologic Cancer
Ovarian Cancer
Uterine Cancer
Cervical Cancer
Keywords: Cancer
Breast Cancer
Gynecologic Cancer
Strength Training
Exercise
Physical Activity
Fatigue
Quality of Life
Strength
Fitness
Cancer Survivor
Survivor
Lead sponsor: Nova Scotia Health Authority
Sponsor class: OTHER
Collaborators: name: Dalhousie University
First posted: 2012-10-18
Enrollment: 20
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SCREENING

Brief summary: The purpose of this study is to compare once-a-week vs. twice-a-week strength training in survivors of breast and gynecologic cancer to determine which is the optimal exercise prescription.

Detailed description: As a result of cancer and its treatment, survivors of breast and gynecologic cancer are reported to have deficits in both physical and psycho-social health. In cancer survivors exercise has been shown to improve fitness, increase bone density and lean body mass, enhance self-esteem, and reduce fatigue. These changes have a positive effect on the survivor's physical functioning and quality of life. However, there are few studies which have examined the effects of strength training or studies aimed at determining optimal exercise prescription in this population. Therefore, the purpose of this study is to compare two strength training prescriptions (once-a-week vs. twice-a-week strength training) to determine which prescription (if any) results in greater benefit for survivors. It is hoped that the results of this study will lead to a better understanding of how strength training improves the health of survivors and will help inform future exercise guidelines for this population.

Eligibility criteria: Inclusion Criteria:

* Female Survivor of Breast or Gynecologic Cancer
* Completed Primary Treatment (hormone treatments are ok)
* 18 years of age or older
* Physician's Permission to Participate

Exclusion Criteria:

* High Risk Individuals (determined by questionnaire)
* Secondary Health Problems that could increase the risk of participating (Includes but not limited to: Uncontrolled angina/hypertension, heart failure, osteoporosis, brain metastases, history of seizures).
* Report participating in a strength training program in the past six (6) months
* Have had a change in medication in the past 30 days

Primary outcomes:
measure: Changes in Muscular Strength
timeFrame: Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)
Secondary outcomes:
measure: Process Measures
timeFrame: Final (end of week 13)
measure: Changes in Muscular Endurance
timeFrame: Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)
measure: Changes in Body Composition
timeFrame: Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)
measure: Changes in Quality of Life
timeFrame: Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)
measure: Changes in Fatigue
timeFrame: Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)
measure: Changes in Physical Activity Levels
timeFrame: Baseline (end of week 1); Midpoint (end of week 7); Final (end of week 13)
Other outcomes:
Locations:
city: Halifax
country: Canada
facility: Exercise Lab: Queen Elizabeth II Dickson Centre
state: Nova Scotia
Study officials:
affiliation: CDHA
name: Scott Grandy, Ph D
role: PRINCIPAL_INVESTIGATOR
References: