Clinical trial NCT02031783: Glucose:Fructose Versus Glucose Carbohydrate Ingestion and Endurance Performance
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Lead sponsor: Société des Produits Nestlé (SPN)
Sponsor class: INDUSTRY
First posted: 2014-01-09
Enrollment: 74
Sex: MALE
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: The primary objective is to show that multiple transportable carbohydrate ingestion is more effective in improving endurance performance compared to single transportable carbohydrate ingestion.


Eligibility criteria: Inclusion Criteria:

* Males aged 18 to 60 years
* A history of competitive triathlon performance (≥ 2 years)
* Participation in at least four competitive triathlon events within the past 2 years
* Be in regular training for triathlon events
* A personal best time for a standard ½ Ironman race (1.9 km swim, 90 km cycle, 21.1 km run) in the last year of either:

  * ≤ 6 h 00 min, for men aged 18-40 years
  * or ≤6 h 05 min for men aged 40-50 years
  * or ≤6 h 20 min for men aged 50-60 years
* Alternatively, if not competed in ½ Ironman in the last year, at least one standard distance triathlon (1.5 km swim, 40 km cycle, 10 km run) within the last 12 months:

  * ≤2 h 13 min, for men aged 18-40 years
  * or ≤2 h 18 min for men aged 40-50 years
  * or ≤2 h 23 min for men aged 50-60 years
* Available to compete in the ½ Ironman events and complete all study requirements
* Experienced in using carbohydrate supplementation, as gels, bars, and drinks in training/racing, specifically at rates ≥60-90g/h)
* Experience of specific formulations may include both or only multiple and single transportable carbohydrates, thus a full assessment would be made prior to recruitment to ensure balance during randomization and account for any association with the primary outcome
* Obtained his (or his legal representative's) informed consent.

Exclusion Criteria:

* Failure to meet health requirements defined in the Health Questionnaire
* Prior known fructose intolerance
* Wheat intolerance or other precluding food or packaging-related allergies
* An existing injury affecting ability to race to best ability
* A chronic injury that may affect ability to complete the races
* Unable to carry out performance assessments and questionnaires correctly
* Unable to tolerate the treatment during the familiarization sessions
* Taking medications thought to interfere with the study outcomes
* Currently participating or having participated in another clinical study during the last four weeks prior to the beginning of this study

Primary outcomes:
measure: TIME to finish a long distance triathlon
timeFrame: Total time recorded at the end of the race 1 and race 2
Secondary outcomes:
Other outcomes:
Locations:
city: Wellington
country: New Zealand
facility: Massey University
Study officials:
References:
citation: Rowlands DS, Houltham SD. Multiple-Transportable Carbohydrate Effect on Long-Distance Triathlon Performance. Med Sci Sports Exerc. 2017 Aug;49(8):1734-1744. doi: 10.1249/MSS.0000000000001278.