Clinical trial NCT06943261: Effects of Task-oriented Training on Visual-motor Integration and Upper Limb Function in Children With Down Syndrome
Official title: Effects of Task-oriented Training on Visual-motor Integration and Upper Limb Function in Children With Down Syndrome
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Down Syndrome
Keywords: Down's syndrome
Visual motor integration
Task-oriented training
Upper limb function
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2025-04-24
Enrollment: 28
Sex: ALL
Minimum age (years): 6
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: A Randomized controlled trial performed in which 28 Down Syndrome children with the age of 6-12 age, will be taken randomly after screening and meeting inclusion criteria. children will be divide in to two groups. Group A (experimental group) will receive task-oriented training of 8 weeks for 30-45 min 3 days a week and (control group) will receive a conventional therapy and game based interventions of 8 weeks for 30-45 min 3 days a week. pre values were take from week 1 and then on week 4 mid values of intervention will be taken and at the end post values of interventions will be taken to measure the effects of both therapies
Primary purpose: OTHER

Brief summary: The condition known as Down Syndrome (DS) is caused by trisomy 21, or the presence of an extra copy of chromosome 21. DS is the most common survivable autosomal aneuploidy and one of the genetically complicated problem compatible with post-term human survival. Based on current birth prevalence, the prevalence of DS is around 25%-40%. It is one of the most prevalent disease. Visual-motor integration difficulties are common in children with DS, which affects their capacity to synchronize hand movements with vision. This may have an impact on ADLS like writing, eating, grooming. Both delays in motor skills and visual processing might cause difficulties in this domain.

This study will be a randomized controlled trial conducted in spectrum clinic. This study will be completed in time duration of 10 months after approval of synopsis. Non-probability convenience sampling technique will be used and 28 participants will be recruited in study after randomization. Informed consent will be taken from gradians then, the subjects will be divided into two groups and the Group A (Experimental group) will receive task-oriented training 3 times a week which focus on exercises that improve UL function and visual motor coordination and Group B (Control group) will receive general physiotherapy plan and game-based interventions. Poor visual motor skills are one of the inclusion criteria, but significant intellectual disability, prior involvement in related interventions, and untreated medical or psychological conditions are among the exclusion criteria. The data will be assessed at the baseline and after 8th week of treatment. After data collection data will be analyzed by using SPSS version 23.


Eligibility criteria: Inclusion Criteria:

* • Diagnosed down syndrome patient

  * Both male and female
  * Age range 5 to 12
  * Children who has poor VM skills

Exclusion Criteria:

* • Sever intellectual disability

  * Previous participation in similar interventions
  * Uncontrolled medical or psychiatric conditions
  * Low communication skills

Primary outcomes:
measure: Jebson Taylor Hand Function Test (JTHFT)
timeFrame: baseline, 4th week,8th week
measure: Beery-Buktenica Developmental Test of Visual-Motor Integration (Beery VMI)
timeFrame: baseline, 4th week,8th week
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Riphah International University
name: Sajal Waheed, MS-PT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Thant AA, Wanpen S, Nualnetr N, Puntumetakul R, Chatchawan U, Hla KM, Khin MT. Effects of task-oriented training on upper extremity functional performance in patients with sub-acute stroke: a randomized controlled trial. J Phys Ther Sci. 2019 Jan;31(1):82-87. doi: 10.1589/jpts.31.82. Epub 2019 Jan 29.