Clinical trial NCT05589805: Comparison of Low-intensity Laser and ESWT in Carpal Tunnel Syndrome
Official title: Comparison of the Effectiveness of Low-intensity Laser and ESWT Treatments in Carpal Tunnel Syndrome
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Carpal Tunnel Syndrome
Keywords: carpal tunnel syndrome
extracorporeal shock wave therapy
laser treatment
Lead sponsor: Abant Izzet Baysal University
Sponsor class: OTHER
First posted: 2022-10-21
Enrollment: 90
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Carpal tunnel syndrome is the most common neuropathy of the median nerve. Conservative methods are used in mild and moderate CTS in the treatment. In this study, we aimed to compare the effectiveness of low-intensity laser and ESWT treatments in patients with mild and moderate carpal tunnel syndrome diagnosed with EMG.

Detailed description: Carpal tunnel syndrome is the most common neuropathy of the median nerve. Its incidence increases between the ages of 40-60. Its prevalence is 4-5%, and incidence is 2.7%. It is more common in women than men. The vast majority of cases are idiopathic.The first symptoms usually start at night. The patient wakes up with a feeling of swelling without any visible swelling and symptoms such as burning, numbness and tingling in the median nerve region.In severe cases, hand weakness and thenar atrophy develop. Provocative tests such as phalen, reverse phalen, tinel, carpal compression test, tourniquet test can be used in the examination.The diagnosis of carpal tunnel syndrome is made by nerve conduction studies and electromyography. Conservative methods are used in mild and moderate CTS in the treatment. Surgical methods are recommended in severe cases and in cases unresponsive to conservative treatment.One of the methods used in the treatment is Laser (Light Amplification by Stimulated Emission of Radiation).There are low and high intensity laser applications according to their energy densities. The basic mechanism of action is tissue stimulation. ESWT (Extracorporeal Shock Wave Therapy), another treatment method, shows therapeutic properties by focusing high-amplitude sound waves on the desired area of the body. Apart from the mechanical effect, it also has an effect at the cellular level.In previous studies, both low-intensity laser and ESWT application were found to be effective in the treatment of carpal tunnel syndrome. However, as far as we know, there is no study comparing the efficacy of low-intensity laser therapy and ESWT therapy in carpal tunnel syndrome. In this study, we aimed to compare the effectiveness of low-intensity laser and ESWT treatments in patients with mild and moderate carpal tunnel syndrome diagnosed with EMG.

Eligibility criteria: Inclusion Criteria:

* 18-65 years
* Having a clinic compatible with carpal tunnel syndrome,
* Patients with electrophysiological data compatible with mild and moderate carpal tunnel syndrome

Exclusion Criteria:

* Cervical radiculopathy , polyneuropathy , brachial plexopathy , thoracic outlet syndrome
* Regular use of oral steroids or nsaii in the last 3 months
* Systemic disease (DM, hypothyroidism, RA, gout, acromegaly, CKD, dialysis)
* Severe carpal tunnel syndrome (kts)

Primary outcomes:
measure: Visual Analog Scale
timeFrame: Baseline
measure: Visual Analog Scale
timeFrame: Post-treatment (3th week)
measure: Boston Scale
timeFrame: Baseline
measure: Boston Scale
timeFrame: Post-treatment (3th week)
measure: Median nerve area measurement
timeFrame: Baseline
measure: Median nerve area measurement
timeFrame: Post-treatment (3th week)
measure: LANNS neuropathic pain scale
timeFrame: Baseline
measure: LANNS neuropathic pain scale
timeFrame: Post-treatment (3th week)
Secondary outcomes:
measure: Visual Analog Scale (paresteshia)
timeFrame: Baseline
measure: Visual Analog Scale (paresteshia)
timeFrame: Post-treatment (3th week)
measure: Ouick Dash Score
timeFrame: Baseline
measure: Ouick Dash Score
timeFrame: Post-treatment (3th week)
Other outcomes:
measure: Hand Grip Force
timeFrame: Baseline
measure: Hand Grip Force
timeFrame: Post-treatment (3th week)
measure: Finger Grip Force
timeFrame: baseline
measure: Finger Grip Force
timeFrame: Post-treatment (3th week)
Locations:
Study officials:
References: