Clinical trial NCT06936436: the Effect of Implanon on Menstrual Patterns
Official title: the Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Menstrual Irregularities
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2025-04-20
Enrollment: 200
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Women will be grouped into:

1. Immediate postpartum (Insertion within 48 hours of delivery).
2. Early postpartum (Insertion between 4-6 weeks postpartum).
3. Late postpartum (Insertion after 6 weeks postpartum

Brief summary: This study aims to evaluate whether the timing of postpartum Implanon insertion (immediately postpartum, early postpartum, or late postpartum) affects menstrual patterns

Detailed description: * Etonogestrel implants (Implanon) are widely used for postpartum contraception. However, the timing of insertion may influence menstrual patterns, including irregular bleeding, amenorrhea, and prolonged bleeding episodes. Despite the increasing use of immediate postpartum contraception, there is limited research on how the timing of Implanon insertion affects menstrual cycle regulation.
* Furthermore, lactation and hormonal changes postpartum may modify the bleeding patterns in women using Implanon, with breastfeeding women experiencing a higher likelihood of amenorrhea due to prolactin-induced suppression of ovulation.
* This study aims to fill these gaps by systematically comparing menstrual outcomes based on timing of Implanon insertion postpartum

Eligibility criteria: Inclusion Criteria:

* Postpartum women opting for Implanon as contraception.
* No contraindications to hormonal contraception.

Exclusion Criteria:

* . Women with known bleeding disorders.
* Use of other hormonal contraceptives during the study period.
* Postpartum complications such as severe infections or retained products of conception

Primary outcomes:
measure: The Effect of Implanon on Menstrual Patterns According to Timing of Insertion After Delivery
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Assiut University
name: AHMED MOHAMED ABBAS, PROF.DR
role: STUDY_CHAIR
affiliation: Assiut University
name: MOHAMED SAYED ABDELLAH, PROF.DR
role: STUDY_CHAIR
affiliation: Assiut University
name: ALAA AHMED MAKHLOUF, DR
role: STUDY_CHAIR
References:
citation: Mazza D, Harrison C, Taft A, Brijnath B, Britt H, Hobbs M, Stewart K, Hussainy S. Current contraceptive management in Australian general practice: an analysis of BEACH data. Med J Aust. 2012 Jul 16;197(2):110-4. doi: 10.5694/mja11.11599.
citation: Richters J, Grulich AE, de Visser RO, Smith AM, Rissel CE. Sex in Australia: contraceptive practices among a representative sample of women. Aust N Z J Public Health. 2003;27(2):210-6. doi: 10.1111/j.1467-842x.2003.tb00810.x.
citation: . Product information: Implanon NXT, Schering-Plough Pty Ltd, 12 November 2010
citation: Product information: Implanon® Implant, Organon (Australia) Pty Ltd, 19 March 2008.