Clinical trial NCT06988371: Responses of Adults Smoking Nondaily and Daily in the Experimental Tobacco Marketplace
Official title: Responses of Adults Smoking Nondaily and Daily in the Experimental Tobacco Marketplace
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Tobacco Use
Cigarette Use
Keywords: tobacco
cigarettes
nondaily smoking
behavioral economics
Lead sponsor: University of Kentucky
Sponsor class: OTHER
Collaborators: name: National Institute on Drug Abuse (NIDA)
First posted: 2025-05-23
Enrollment: 800
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Mixed crossover-factorial
Primary purpose: OTHER

Brief summary: The goal of this project is to learn about the potential impact of tobacco regulations that could affect the availability of tobacco products among adults who smoke nondaily and daily. Nondaily smoking is increasingly common and tobacco regulation research should consider how FDA actions may impact this group. Participants will be asked to complete online surveys and tests, online shopping sessions in a simulated Experimental Tobacco Marketplace. Reactions and decisions of adults who smoke nondaily and daily will be compared.

Detailed description: After granting informed consent, participants will complete the single assessment.

First, investigators will collect information from participants on personal characteristics, substance use patterns and addiction severity, and behavioral and cognitive tasks that measure components of our behavioral economic model of product valuation.

Experimental Tobacco Marketplace. In this procedure, participants will complete purchasing scenarios in a realistic tobacco/nicotine product marketplace to model and examine the impact of each of the proposed tobacco product regulations. Participants will be seated in front of a computer to access a simulated online tobacco marketplace with an interface similar to many online merchants. This will allow participants to browse through the selection of tobacco products and add as many as they desire of each product to the virtual shopping cart. Each product will have the price clearly displayed along with an image and description of the product. The selection of products will vary based on the particular regulatory scenario that is being modeled. In each pricing scenario during each marketplace session, participants will be asked to make nicotine-product purchases sufficient for one week's use from this marketplace. During a purchasing session, the participant will be provided with a virtual budget that matches their actual weekly budget for nicotine/tobacco products, a procedure our team has shown to generate realistic results. Participants will use that virtual budget to indicate which selection of products they would purchase from those available in the marketplace.

Eligibility criteria: Inclusion Criteria:

* At least 18 years old
* Consume cigarettes 4-30 days per month
* Have no plans to quit nicotine/tobacco products
* Read and understand English

Exclusion Criteria:

Primary outcomes:
measure: Aggregate behavioral economic demand across all participants under the proposed regulatory environments
timeFrame: Baseline
measure: Aggregate behavioral economic substitution across all participants under the proposed regulatory environments
timeFrame: Baseline
Secondary outcomes:
measure: Hypothetical quantity purchased in purchase tasks
timeFrame: Baseline
measure: Delay Discounting Tasks
timeFrame: Baseline
Other outcomes:
Locations:
city: Lexington
country: United States
facility: University of Kentucky
state: Kentucky
Study officials:
affiliation: University of Kentucky
name: Bethany Shorey Fennell, PhD
role: PRINCIPAL_INVESTIGATOR
References: