Clinical trial NCT06976970: Diet Quality And Metabolic Syndrome In Adult Individuals: Evaluation Of Turkey Nutrition And Health Survey 2017
Official title: Diet Quality And Metabolic Syndrome In Adult Individuals: Evaluation Of Turkey Nutrition And Health Survey 2017
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Metabolic Syndrome
Keywords: Metabolic Syndrome
Diet Quality
Healthy Eating Index (HEI-2015)
Dietary Inflammatory Index (DII)
Mediterranean Diet Score (mMDS)
DASH Diet
Lead sponsor: Marmara University
Sponsor class: OTHER
First posted: 2025-05-16
Enrollment: 4915
Sex: ALL
Minimum age (years): 19
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The study population consists of adults aged 19 years and older who participated in the 2017 Turkey Nutrition and Health Survey (TNHS), conducted by the Turkish Ministry of Health. This secondary data analysis includes participants with complete dietary, demographic, anthropometric, and biochemical data. Exclusion criteria were: pregnant or lactating women, individuals with cancer, psychiatric or neurological disorders, those on specific therapeutic diets, individuals with missing key variables, and those with implausible energy intake levels (\<800 or \>4000 kcal/day for men, \<500 or \>3500 kcal/day for women).

Brief summary: This study investigates how the quality of a person's diet may be related to metabolic syndrome, which includes health issues such as high blood pressure, high blood sugar, and abdominal obesity. The research uses existing data from the 2017 Turkey Nutrition and Health Survey, focusing on adults aged 19 and over. The study does not involve any medical treatments or new data collection. It aims to support public health efforts by identifying links between eating patterns and metabolic health in the Turkish population.

Detailed description: This study is a secondary analysis of the 2017 Turkey Nutrition and Health Survey (TNHS), which was conducted by the Ministry of Health to assess the health and nutritional status of the Turkish population. The objective of this cross-sectional observational study is to evaluate the relationship between diet quality and the presence of metabolic syndrome (MetS) among Turkish adults aged 19 years and older.

Diet quality will be assessed using several validated dietary indices, including the Healthy Eating Index-2015 (HEI-2015), the Dietary Inflammatory Index (DII), the modified Mediterranean Diet Score (MDS), and the DASH (Dietary Approaches to Stop Hypertension) score. These indices provide a comprehensive evaluation of overall dietary patterns and their potential impact on metabolic health.

Metabolic syndrome will be defined based on the Joint Interim Statement (2009) criteria. Participants will be classified as having metabolic syndrome if at least three of the following five components are present: abdominal obesity, elevated blood pressure or receiving antihypertensive treatment, reduced HDL cholesterol levels or receiving treatment for dyslipidemia, elevated triglyceride levels or receiving lipid-lowering therapy, and elevated fasting blood glucose or receiving treatment for hyperglycemia.

Statistical analysis will include descriptive statistics, t-tests or Mann-Whitney U tests for comparisons between MetS and non-MetS groups, and multivariate logistic regression analyses to determine the associations between dietary indices and the likelihood of having MetS, adjusting for relevant sociodemographic and lifestyle covariates.

Statistical analyses were conducted using SPSS version 22.0. Descriptive statistics included frequencies and percentages for categorical variables and means with standard deviations or medians with ranges for continuous variables, depending on the distribution. Normality was assessed using the Shapiro-Wilk test. Group comparisons were performed using the Mann-Whitney U test or Kruskal-Wallis test for non-normally distributed variables and the Chi-square test for categorical variables. Correlations between continuous variables were evaluated using Spearman's rank correlation coefficient. Binary logistic regression analysis was used to identify factors associated with the presence of metabolic syndrome. A p-value of \<0.05 was considered statistically significant.

This study is expected to contribute to the national evidence base on dietary patterns and metabolic health and to inform public health strategies aiming to reduce the burden of non-communicable diseases in Turkiye.

Eligibility criteria: Inclusion Criteria:

* 19 years and older
* Participated in the 2017 Turkey Nutrition and Health Survey (TNHS)

Exclusion Criteria:

* Pregnant or lactating women, individuals with cancer, psychiatric or neurological disorders, those on specific therapeutic diets, individuals with missing key variables, and those with implausible energy intake levels (\<800 or \>4000 kcal/day for men, \<500 or \>3500 kcal/day for women).

Primary outcomes:
measure: Metabolic Syndrome (MetS)
timeFrame: Day 1
measure: HEI-2015 Score
timeFrame: Day 1
measure: Dietary Inflammatory Index (DII)
timeFrame: Day 1
measure: Mediterranean Diet Score (MDS)
timeFrame: Day 1
measure: DASH Score (Dietary Approaches to Stop Hypertension)
timeFrame: Day 1
Secondary outcomes:
Other outcomes:
Locations:
city: Samsun
country: Turkey
facility: Ondokuz Mayıs University
Study officials:
affiliation: Marmara University
name: Elif Akbas, Research Assistant
role: PRINCIPAL_INVESTIGATOR
affiliation: Ondokuz Mayıs University
name: Yasemin Ertas Ozturk, Assistant Professor
role: PRINCIPAL_INVESTIGATOR
References: