Clinical trial NCT06530433: Enhanced Community First Responder System Evaluation in Singapore
Official title: Evaluation of an Enhanced Community First Responder Support System to Improve Bystander Cardiopulmonary Resuscitation Quality for Patients Experiencing Out-of-hospital Cardiac Arrest
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Out-Of-Hospital Cardiac Arrest
Keywords: cardiopulmonary resuscitation
Bystander CPR
Community first responder
CPRCard
TCPR Link
Lead sponsor: Singapore General Hospital
Sponsor class: OTHER
Collaborators: name: Duke-NUS Graduate Medical School
First posted: 2024-07-31
Enrollment: 165
Sex: ALL
Minimum age (years): 21
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: This Health Services research intervention will evaluate effect of live CPR video CPR performance of the volunteer to call-taker in improving CPR Quality and clinical outcomes among the OHCA patients.
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The rise in out-of-hospital cardiac arrest (OHCA) cases in Singapore highlights the need for effective bystander cardiopulmonary resuscitation (BCPR). Despite many lay responders performing CPR, survival rates with good neurological outcomes have not significantly improved, prompting research into the quality of CPR as a critical factor. The study by Gallagher EJ et al. showed a significant survival improvement with high-quality CPR.

To address this, the Unit of Pre-hospital and Emergency Research (UPEC) trained thousands of community first responders (CFRs) in simplified CPR techniques using hands-only and DA-CPR methods. A significant innovation is the CPRcard®, developed by Laerdal in Norway, which offers real-time feedback on the quality of chest compressions. However, only 36% of CFRs using the CPRcard® achieved the desired compression standards, indicating room for improvement.

The study proposes enhancing CFR support with information communication technology (ICT), enabling two-way audio and one-way video communication between CFRs and dispatchers. This aims to reduce stress among responders, increase their willingness to engage with OHCA alerts, and improve CPR quality.

The clinical trial in Singapore will compare the current system against the enhanced CFR support system (eCSS), focusing on the real-time relay of CPR performance data, communication ease, and implementation factors. The high-quality CFR and OHCA registries in Singapore provide a robust setting for this research, aiming to enhance CPR delivery and improve OHCA outcomes through technology and real-time support.


Eligibility criteria: Inclusion Criteria:

* 18 years old and above
* SCDF registered CFRs
* Trial dispatchers with an active account of myResponder® app on their mobile phones

Exclusion Criteria:

* The CFRs who are pregnant
* Experiencing any serious physical Conditions
* Mental Health Conditions

Primary outcomes:
measure: Good Chest Compression Depth (4-6cm)
timeFrame: Throughout chest compression before handing over to EMS (up to 24 hours)
Secondary outcomes:
measure: Survivor discharging rate
timeFrame: Throughout Hospital Admission (up to 1 year)
Other outcomes:
Locations:
city: Singapore
country: Singapore
facility: Duke-NUS Medical School
state: Sigapore
Study officials:
References:
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