Clinical trial NCT05611983: Experience and Feasibility of Methods for Early Sensory Training
Official title: Experience and Feasibility of Methods for Early Sensory Training Phase 1 - From a User Perspective
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Nerve Injury
Peripheral Nerve Injuries
Keywords: periferal nerve injuries
sensory relearning
rehabilitation
imagery
mirror therapy
Lead sponsor: Lund University Hospital
Sponsor class: OTHER
First posted: 2022-11-10
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: The good effects of using guided plasticity for a rehabilitative purpose in case of nerve damage have been shown, but a problem that has been presented is that some individuals find it difficult to assimilate these effects due to difficulties in carrying out abstract training or due to a lack of motivation. In early sensory training, the plasticity of the brain is used. Methods for early sensory training that have been described are: 1) mental imagery of touch (mental imagery), 2) observation of touch, 3) mirror training, 4) use of images for visualization of touch. The method needs to be developed and refined to be able to offer individual training plans in order to find a motivating and meaningful form of training.


Eligibility criteria: Inclusion Criteria:

* \>= 50% injury of N. Medianus/ N. Ulnaris or 100% digital nerve injury dig I and/or dig II
* Ålder: ≥ 18 år

Exclusion Criteria:

* Impaired cognitive ability
* Documented psychiatric diagnosis
* Inability to master the Swedish language

Primary outcomes:
measure: PETS - The Problematic Experience of Therapy Scale
timeFrame: 4 weeks post intervention
measure: ESRQ - Early sensory relearing questionaire
timeFrame: 4 weeks post intervention
Secondary outcomes:
Other outcomes:
Locations:
city: Malmö
country: Sweden
facility: Skane university hospital
state: Skane
Study officials:
affiliation: Lund University/Region Skane
name: Lars Dahlin, Prof
role: STUDY_CHAIR
References:
citation: Vikstrom P, Carlsson I, Rosen B, Bjorkman A. Patients' views on early sensory relearning following nerve repair-a Q-methodology study. J Hand Ther. 2018 Oct-Dec;31(4):443-450. doi: 10.1016/j.jht.2017.07.003. Epub 2017 Sep 28.
citation: Rosen B, Vikstrom P, Turner S, McGrouther DA, Selles RW, Schreuders TA, Bjorkman A. Enhanced early sensory outcome after nerve repair as a result of immediate post-operative re-learning: a randomized controlled trial. J Hand Surg Eur Vol. 2015 Jul;40(6):598-606. doi: 10.1177/1753193414553163. Epub 2014 Oct 7.
citation: Bassolino M, Campanella M, Bove M, Pozzo T, Fadiga L. Training the motor cortex by observing the actions of others during immobilization. Cereb Cortex. 2014 Dec;24(12):3268-76. doi: 10.1093/cercor/bht190. Epub 2013 Jul 29.
citation: Duffau H. Brain plasticity: from pathophysiological mechanisms to therapeutic applications. J Clin Neurosci. 2006 Nov;13(9):885-97. doi: 10.1016/j.jocn.2005.11.045. Epub 2006 Oct 17.
citation: Vikstrom P, Rosen B, Carlsson IK, Bjorkman A. The effect of early relearning on sensory recovery 4 to 9 years after nerve repair: a report of a randomized controlled study. J Hand Surg Eur Vol. 2018 Jul;43(6):626-630. doi: 10.1177/1753193418767024. Epub 2018 Apr 16.