Clinical trial NCT04224298: Preliminary Study on Eye Features of Patients With Malignant Tumors
Official title: Application of White Eye Imaging Health Care System on Diagnosis of Malignant Tumors
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Feature Elongation
Cancer Patients
Keywords: Eye
Manifestations
Cancer
Lead sponsor: Peking University Cancer Hospital & Institute
Sponsor class: OTHER
First posted: 2020-01-13
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Participants in the study were patients with malignant tumors and healthy volunteers.

Brief summary: Based on the theory of traditional Chinese Medicine, this study collects eye features of white eyes through the White Eye Imaging Health Care System under visible light and establishes a database of eye-eye features corresponding to the disease. The computer image analysis and artificial intelligence technology are used to visualize the eye. The features were extracted and classified, and the corresponding changes in the characteristics of the traditional Chinese medicine and the disease were analyzed statistically to establish an analytical model corresponding to the disease.

Detailed description: 1. Collecting the white-eyed eye features of 500 patients with malignant tumors and 500 non-tumor patients by the white-eye shadowless imaging acquisition system under visible light, and establishing eye-catching images of malignant tumor patients and healthy people of different diseases. Feature database.
2. Based on the collected four-dimensional eye-eye diagram, using computer image analysis and artificial intelligence technology to extract and classify the eye-eye features of the white eye, and statistically analyze the correlation between the eye-eye features and the malignant tumor. The relationship between the characteristics of the white eye and the corresponding change of malignant tumor.

Eligibility criteria: Inclusion Criteria:

* Malignant tumor patients with clear pathological diagnosis;

  * Those who have no serious primary diseases of the cardiovascular, cerebrovascular, respiratory, endocrine, urinary, blood and other systems;

    * The main organs (hematopoiesis, heart, lung, liver, and kidney) have no obvious abnormal function; ④Age ≥18 years old, ≤75 years old; ⑤ No serious eye disease;

      * The patient volunteered to participate in this study.

Exclusion Criteria:

* Patients with severe blood loss (because when the bleeding exceeds 300ml, the white eye color of the patient is often pale white);

  * Poor patient compliance; ③ pregnant and lactating women;

    * Can't cooperate with inspection properly; ⑤ Cannot read or understand the scale.

Primary outcomes:
measure: Model of white-eye ocular features in patients with malignant tumors
timeFrame: 2.5 years
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Yichen Dr. Xu
Study officials:
affiliation: Peking University Cancer Hospital & Institute
name: Dong D Xue
role: PRINCIPAL_INVESTIGATOR
References: