Clinical trial NCT06527651: Effects of Ultrasound-guided Genicular Nerve Block in Knee Osteoarthritis Patients on Proprioception and Static Balance
Official title: Effects of Ultrasound-guided Genicular Nerve Block in Knee Osteoarthritis Patients on Proprioception and Static Balance
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoarthritis
Osteoarthritis, Knee
Proprioceptive Disorders
Balance; Distorted
Lead sponsor: Ankara City Hospital Bilkent
Sponsor class: OTHER
First posted: 2024-07-30
Enrollment: 22
Sex: ALL
Minimum age (years): 50
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Genicular nerve block (GNB) is a novel and promising interventional method for pain in knee osteoarthritis (KOA). However ,it contains afferent fibers that receive impulses from proprioceptive and deep sensory receptors located in the joint capsule, ligaments, muscles, tendons and periosteum. These proprioceptive stimuli are effective on joint position and biomechanics, protect the joint from injuries and help maintain balance. This study aims to evaluate Pproprioception and static balance after ultrasound-guided GNB in patients with knee osteoarthritis.

Detailed description: Genicular nerve block (GNB) is a novel and promising interventional method for pain in knee osteoarthritis (KOA). However ,it contains afferent fibers that receive impulses from proprioceptive and deep sensory receptors located in the joint capsule, ligaments, muscles, tendons and periosteum. These proprioceptive stimuli are effective on joint position and biomechanics, protect the joint from injuries and help maintain balance. This study aims to evaluate Pproprioception and static balance after ultrasound-guided GNB in patients with knee osteoarthritis.

Eligibility criteria: Inclusion Criteria:

* Chronic knee pain more than \>3 according to visual analog scale (VAS) and difficulty in function more than 3 months
* Grade 2-3 KOA according to the Kellgren -Lawrence radiological grading system
* No significant improvement in response to conservative treatments such as analgesics and physiotherapy.

Exclusion Criteria:

* History of trauma, fractures, malignencies, surgery and inflammatory diseases of knee
* Limitation of range of motion in unilaterally and/or bilaterally in knee joint
* Allergies of pharmacological agents using during procedure (lidocaine)
* Presence of intra-articular or peri-articular injection such as hyaluronic acids, corticosteroids or collagen supplements at last 6 months
* Other neurologic or rheumatological conditions that may lead vertigo or vestibular disfunction or presence of impairment in proprioception such as polineuropathy
* Presence of diabetes mellitus due to risk of small fiber neuropathy
* Cognitive impairment and uncontrolled systemic conditions.

Primary outcomes:
measure: Visual analog scale (VAS)
timeFrame: 24 hours
measure: HUR SmartBalance®: HUR SmartBalance®
timeFrame: 24 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Ankara Bilkent City Hospital
Study officials:
References: