Clinical trial NCT04140383: Cataract Surgery In Patients With Advanced Age
Official title: Outcomes of Cataract Surgeries in Patients With Advanced Age
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cataract Senile
Keywords: geriatry
cataract surgery
advanced age
Lead sponsor: Sakarya University
Sponsor class: OTHER
First posted: 2019-10-25
Enrollment: 152
Sex: ALL
Minimum age (years): 65
Maximum age (years): 95
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patients aged 65 years and older who underwent cataract surgery

Brief summary: This study evaluates and compares clinical outcomes of \< 85 and ≥ 85 year old patients who underwent cataract surgeries.

Detailed description: The medical records of patients who were underwent cataract surgery between January 2014 and October 2017 were investigated retrospectively and patients 65 years and older were recruited. Two groups were made according to age: group1 composed of patients age range between 65 and 85 years and group 2 composed of patients 85 years and older. Gender, presence of diabetes mellitus (DM), hypertension (HT), drug use were noted.

The results of best corrected visual acuity (BCVA) converted to LogMar, intraocular pressure (IOP) before and 3 months after operation, biomicroscopic and fundus examinations were investigated.

Additional ocular diseases such as glaucoma, age related macular degeneration (AMD), pseudoexfoliation syndrome, retinopathies and maculopathies related to systemic diseases were noted. Pupil dilation properties were also noted as poor, mid or full pupil dilation.

Cataract surgery techniques such as phacoemulsification, extra- and intracapsular lens extractions, peroperative complications, intracameral drug use were investigated.

these aforementioned outcomes evaluated and compared between groups.

Eligibility criteria: Inclusion Criteria:

* patients aged 65 years and older patients who underwent cataract surgery

Exclusion Criteria:

* patients aged below 65 years who underwent cataract surgery

Primary outcomes:
measure: Best corrected visual acuity
timeFrame: Before cataract surgery
measure: Best corrected visual acuity
timeFrame: three months after cataract surgery
Secondary outcomes:
measure: presence of Diabetes Mellitus
timeFrame: Baseline (Before cataract surgery)
measure: presence of essential hypertension
timeFrame: before cataract surgery
measure: oral acetylsalicylic acid use
timeFrame: before cataract surgery
measure: oral flomax use
timeFrame: before cataract surgery
measure: presence of age related macular degeneration
timeFrame: Baseline (Before cataract surgery)
measure: presence of glaucoma
timeFrame: before cataract surgery
measure: presence of pseudoexfoliation
timeFrame: before cataract surgery
measure: presence of poor pupil dilation
timeFrame: During cataract surgery
measure: presence of zonule deficiency
timeFrame: During cataract surgery
measure: Cataract types in patients who underwent cataract surgery
timeFrame: Baseline (Before cataract surgery)
measure: measurement of effective phacoemulsification time
timeFrame: During cataract surgery
measure: presence of posterior capsule rupture
timeFrame: During cataract surgery
measure: anterior vitrectomy
timeFrame: during surgery
measure: presence of aphakia
timeFrame: 3 months after cataract surgery
measure: intracameral adrenalin use
timeFrame: during surgery
Other outcomes:
Locations:
city: Sakarya
country: Turkey
facility: Sakarya University Ophthalmology Department
Study officials:
affiliation: Sakarya University
name: Burcin Cakir, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Syam PP, Eleftheriadis H, Casswell AG, Brittain GP, McLeod BK, Liu CS. Clinical outcome following cataract surgery in very elderly patients. Eye (Lond). 2004 Jan;18(1):59-62. doi: 10.1038/sj.eye.6700521.