Clinical trial NCT04019132: Power During Functional Tasks in Older Adults
Official title: Power During Functional Tasks in Older Adults: Reliability, Reference Values and Relationship With Other Outcome Measurements Related to Sarcopenia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Aging
Keywords: Muscle Power
Functional capacity
Lead sponsor: Universitaire Ziekenhuizen KU Leuven
Sponsor class: OTHER
First posted: 2019-07-15
Enrollment: 284
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Healthy young to older adults

Brief summary: The primary aim of this study is to optimize the methodology to measure lower limb power in older adults, so that clinicians are able to detect functional problems in this population earlier.

Detailed description: Aging is associated with slower movement patterns, a higher fall risk and a restriction in functionality. This will lead to an increase in the number of dependent elderly and a high socio-economic burden. From the age of 40, a systematic loss of muscle mass and muscle force, also known as sarcopenia, will occur. In addition, performing daily tasks requires the production of muscle force at a certain speed. The product of force and speed, power, decreases even earlier and faster than muscle force.

This power is typically measured with specialized equipment, which limits the large-scale applicability. With the help of accelerometry there is the possibility to measure power during more functional tasks and movements, which benefits the applicability, but the reliability, reference values and link with other outcome measurements related to sarcopenia has to be investigated.

Eligibility criteria: Inclusion Criteria:

* Age \>20

Exclusion Criteria:

* Unstable cardiovascular diseases
* Fever or acute infection
* Cognitive or physical malfunctioning that hinders the understanding or performance of tests and/or instructions

Primary outcomes:
measure: Lower limb muscle power during a stair climb test
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Lower limb muscle power during a sit-to-stand test
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Reliability of power measurements measured with a 3D accelerometer
timeFrame: 1 test moment of approximately 30 minutes, planned between September 2019 and July 2020
measure: Rate of power (force-velocity) development
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Handgrip strength
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Jumping height
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Physical activity
timeFrame: 1 week
measure: Number of steps/stairs a day
timeFrame: 1 week
Secondary outcomes:
measure: Number of repetitions during a 30s sit-to-stand test
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: 6min walk distance
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Balance
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Maximal gait speed
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Usual gait speed
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Maximal isometric strength
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
measure: Maximal isokinetic strength
timeFrame: 1 test moment of approximately 1 hour, planned between September 2019 and July 2020
Other outcomes:
Locations:
city: Leuven
country: Belgium
facility: KU Leuven - Department of Movement Sciences
state: Vlaams-Brabant
Study officials:
References: