Clinical trial NCT01870271: Pilot-Study DCPT for PTSD in Adolescents and Young Adults
Official title: Pilotstudie Developmentally Adapted Cognitive Processing Therapy für Jugendliche Und Junge Erwachsene Mit Posttraumatischer Belastungsstörung Nach Sexualisierter Und /Oder körperlicher Gewalt (Pilot DCPT)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: PTSD
Keywords: PTSD
childhood sexual abuse
physical abuse
developmentally adapted cognitive processing therapy
Lead sponsor: Goethe University
Sponsor class: OTHER
Collaborators: name: Katholische Universität Eichstätt Ingolstadt
name: Freie Universität Berlin
First posted: 2013-06-06
Enrollment: 12
Sex: ALL
Minimum age (years): 14
Maximum age (years): 21
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The aim of this pilot study is to evaluate the developmentally adapted cognitive processing therapy (D-CPT)in adolescents suffering from childhood abuse(CA)or physical abuse (PA) related PTSD. D-CPT's feasibility and efficacy will be examined in 20 adolescents suffering from CA or PA-related PTSD in a multicenter study (3 sites).Patients will be assessed prior to (t0), post (t1) and 6 weeks after treatment (t2). Assessments include Clinician Administered PTSD Scale (CAPS), UCLA PTSD Index (UCLA), Beck Depression Inventory (BDI), Adolescent Dissociative Experiences Scale (A-DES), and Borderline Symptom List (BSL-23).

Detailed description: The aim of this pilot study is to evaluate the developmentally adapted cognitive processing therapy (D-CPT)in adolescents suffering from childhood sexual abuse (CA) or childhood physical abuse (PA) related PTSD. D-CPT's feasibility and efficacy will be examined in 20 adolescents suffering from CA or PA-related PTSD in a multicenter study in Berlin, Frankfurt and Ingolstadt in Germany (3 sites).Patients will be assessed prior to (t0), post (t1) and 6 weeks after treatment (t2). Assessments include Clinician Administered PTSD Scale (CAPS), UCLA PTSD Index (UCLA), Beck Depression Inventory (BDI), Adolescent Dissociative Experiences Scale (A-DES), and Borderline Symptom List (BSL-23).

Eligibility criteria: Inclusion Criteria:

* PTSD after CSA and/or CPA beyond the age of three (confirmed by a structured clinical interview, CAPS-CA, German Version IBS-KJ)
* PTSD must be the primary diagnosis (most severe disorder according to SCID)
* age 14 - 21 years
* living in safe conditions
* informed consent from parents/legal guardians (if under 18) and participant

Exclusion Criteria:

* current psychotic
* substance related or organic mental disorder
* acute suicidality, severe medical conditions
* mental retardation
* insufficient knowledge of German language.

Primary outcomes:
measure: Clinician-Administered PTSD-Scale for Children and Adolescents
timeFrame: t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up
Secondary outcomes:
measure: UCLA PTSD Index (UCLA)
timeFrame: t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up
measure: Beck Depression Inventory
timeFrame: t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up
Other outcomes:
measure: Borderline Symptom List (BSL-23)
timeFrame: t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up
Locations:
city: Frankfurt
country: Germany
facility: Department of Clinical Psychology and Psychotherapy, Goethe University
state: Hessen
Study officials:
affiliation: Goethe University
name: Regina Steil, PhD
role: PRINCIPAL_INVESTIGATOR
References: