Clinical trial NCT01749007: Assessment of Cognitive Functioning as it Relates to Risk for Suicide in Veterans With HIV/AIDS
Official title: Assessment of Cognitive Functioning as it Relates to Risk for Suicide in Veterans With HIV/AIDS
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: HIV/AIDS
Keywords: Veterans
HIV
AIDS
Cognitive Functioning
Suicide
Lead sponsor: VA Eastern Colorado Health Care System
Sponsor class: FED
First posted: 2012-12-13
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Veterans with HIV/AIDS

Brief summary: The purpose of this project is to gather pilot data related to exploring relationships between cognitive impairment and/or psychiatric distress and suicidal thoughts and/or behaviors in Veterans with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). To achieve this goal, a neuropsychological battery will be administered to Veterans with HIV/AIDS.


Eligibility criteria: Inclusion Criteria:

* Veterans between ages 18 to 65
* Have a diagnosis of HIV/AIDS confirmed via medical record
* Currently receiving or eligible to receive physical and/or mental health care through the VA Eastern Colorado Health Care System

Exclusion Criteria:

* Acute intoxication via alcohol or other illicit drugs at time of assessment as determined by observation and/or interview.
* Psychosis at time of interview as determined by observation and/or interview.
* Poor Test of Memory Malingering (TOMM) performance (scores below 25 on Trial 1 or scores lower than 45 on Trial 2)
* Current status as a prisoner

Primary outcomes:
measure: Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV)
timeFrame: 1 Time Administration
measure: Trail Making Test (TMT): Parts A & B
timeFrame: 1 Time Administration
measure: California Verbal Learning Test, Second Edition (CVLT-II)
timeFrame: 1 Time Adminstration
measure: Delis-Kaplan Executive Function System (D-KEFS)
timeFrame: 1 Time Administration
measure: Brief VisuoSpatial Memory Test-Revised (BVMT-R)
timeFrame: 1 Time Administration
measure: Wisconsin Card Sorting Test (WCST)
timeFrame: 1 Time Administration
measure: Outcome Questionnaire (OQ-45)
timeFrame: 1 Time Administration
measure: Beck Scale for Suicide Ideation (BSS)
timeFrame: 1 Time Administration
Secondary outcomes:
measure: Health Status Questionnaire (HSQ)
timeFrame: 1 Time Administration
measure: University of Washington Risk Assessment Protocol-Revised (UWRAP)
timeFrame: 1 Time Administration
measure: Test of Memory Malingering (TOMM)
timeFrame: 1 Time Administration
measure: The Structured Clinical Interview for DSM-IV-Research Version (SCID-I)
timeFrame: 1 Time Administration
measure: Lifetime Suicide Attempt Self Injury Interview (L-SASI)
timeFrame: 1 Time Administration
measure: Participant Demographics Form
timeFrame: 1 Time Administration
measure: Ohio State University TBI-ID (OSU TBI-ID) Short Form
timeFrame: 1 Time Administration
measure: Beck Hopelessness Scale (BHS)
timeFrame: 1 Time Administration
measure: The Beck Depression Inventory (BDI-II)
timeFrame: 1 Time Administration
measure: The Beck Anxiety Inventory (BAI)
timeFrame: 1 Time Administration
measure: Military Suicide Research Consortium (MSRC) Common Data Elements
timeFrame: 1 Time Administration
Other outcomes:
Locations:
city: Denver
country: United States
facility: Eastern Colorado Health Care System
state: Colorado
Study officials:
affiliation: VISN 19 Denver VA MIRECC
name: Gina Signoracci, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: