Clinical trial NCT05475587: The Association Between Body Constitution and Meridian Energy in Prediabetes
Official title: The Association Between Body Constitution and Meridian Energy Among Individuals With Prediabetes
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Prediabetes
Keywords: prediabetes
traditional Chinese medicine
body constitution
Lead sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Sponsor class: OTHER
First posted: 2022-07-27
Enrollment: 60
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The researchers included 30 adults with prediabetes and 30 healthy controls, matched for age and sex, recruited from the outpatient clinic and health examination center at a teaching hospital in northern Taiwan.

Brief summary: Traditional Chinese medicine (TCM) theories assert that body constitution and meridian energy are the foundations for disease prevention. However, few studies have incorporated TCM concepts into risk factors. This study aimed to examine the association between body constitution and meridian energy in individuals with prediabetes. We conducted a matched case-control study that included 60 individuals with prediabetes. Finally, the reseachers have found that body constitution may be a risk factor fpr progression to type 2 diabetes mellitus in individuals with prediabetes.

Detailed description: Objective: Traditional Chinese medicine (TCM) theories assert that body constitution and meridian energy are the foundations for disease prevention. However, few studies have incorporated TCM concepts into risk factors. This study aimed to examine the association between body constitution and meridian energy in patients with prediabetes.

Methods: The researchers conducted a matched case-control study from January to December 2019 that included 30 adults with prediabetes and 30 healthy controls, matched for age and sex, recruited from the outpatient clinic and health examination center at a teaching hospital in northern Taiwan. Body constitution was measured using the Body Constitution Questionnaire, which classifies the constitution as yang-deficiency, ying-deficiency, and phlegm-stasis, while meridian energy was measured using an Aetoscan meridian energy device (Aeto Technology Co. Ltd., Taiwan). The associations between body constitution, meridian energy, and prediabetes were examined using binary logistic regression analyses.

Conclusion: Body constitution may be a risk factor for progression to type 2 diabetes mellitus in patients with prediabetes and warrants further study.

Eligibility criteria: Inclusion Criteria:

* Previously diagnosed prediabetes with a hemoglobin A1c (HbA1c) of 5.7-6.4% and a f asting plasma glucose (FPG) of 100-125 mg/dL
* Aged ≥20
* provided informed consent
* The controls were healthy individuals whose FPG level was 100 mg/dL in at least two blood tests in the past 6 months.

Exclusion Criteria:

* Use of a hypoglycemic agent within the past 3 months
* Self-reported catastrophic illness in the last 6 months
* Pregnant and/or lactating
* Presence of pacemaker.

Primary outcomes:
measure: Body constitution of body constitution questionnaire (BCQ)
timeFrame: One year
Secondary outcomes:
Other outcomes:
Locations:
city: New Taipei City
country: Taiwan
facility: Taipei Tzu Chi Hospital
Study officials:
References: