Clinical trial NCT00571571: Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents
Official title: Application and Evaluation of Transference Focused Psychotherapy Modified for Adolescents
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Identity Pathology
Behavior Problems
Keywords: Identity difussion
Adolescent psychotherapy
Transference Focused Psychotherapy for Adolescents
Identity
Identity crisis
Identity pathology
Lead sponsor: Weill Medical College of Cornell University
Sponsor class: OTHER
First posted: 2007-12-12
Enrollment: 20
Sex: FEMALE
Minimum age (years): 14
Maximum age (years): 21
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Normal adolescence requires a successful resolution of identity crisis, which results in the development of satisfying relationships, success in school/work pursuits, and achievement of personal goals. Adolescents, who do not resolve this crisis, are at high risk for problems in those areas of functioning. Transference Focused Psychotherapy for Adolescents (TFP-A) is a treatment that specifically addresses these issues, permitting adolescents to develop satisfying friendships, more appropriate interactions with authority, and achieve realistic life goals.

This study will evaluate the application of TFP-A, (a empirically validated treatment for adults with identity disturbance), to adolescents exhibiting the same behavioral and identity pathology. Subjects will be females; ages 14-21, with behaviors associated with identity problems, interpersonal difficulties with teachers, parents and/or peers, and live with their families. These adolescents will be randomly assigned to one of two treatment cells, TFP-A or Treatment as Usual (TAU). Subjects in TFP-A will receive weekly individual therapy for six months. The TAU group will receive standard individual therapy in the Outpatient Department. Both will receive medication as necessary. All subjects will participate in initial, weekly, and bi-monthly assessments during the six-month treatment period, and participate in a naturalistic follow-up study for an additional six months.

Hypothesis:

Adolescents with identity problems as seen in interpersonal, school, and/or family difficulties in the Transference Focused Psychotherapy for Adolescents (TFP-A) group will reduce these problem behaviors and improve management of their feelings and moods compared to adolescents with identity problems in the treatment as usual control group (TAU).


Eligibility criteria: Inclusion Criteria:

1. Female Adolescents, ages 14-21
2. A score of five out of nine critical items on the Borderline Personality Disorder Dimension Interview Scale.
3. Have interpersonal difficulties in school, family, and/or peer functioning.
4. Live at home with family.
5. Willingness to attend evaluation sessions and weekly, individual therapy.

Exclusion Criteria:

1. The presence of psychosis, substance dependence, non-verbal learning disability, antisocial behavior, and/or primary diagnoses of eating disorder, bipolar disorder, and obsessive-compulsive disorder.
2. The need for hospitalization for symptom management.
3. Significant cognitive impairment (Full Scale IQ \<85).
4. The presence of a life-threatening medical illness.

Primary outcomes:
measure: Reduction in interpersonal difficulties with parents, teachers, and/or peers. Improved management of their feelings and moods. Reduction in other problems behaviors (i.e. substance use, self-injurious behaviors)
timeFrame: Subjects will be assessed at entry, 2 month, 4 months, 6 months, 8 months 10 months, and 12 months
Secondary outcomes:
Other outcomes:
Locations:
city: White Plains
country: United States
facility: New York-Presbyterian Hospital
state: New York
Study officials:
affiliation: Weill Medical College of Cornell University
name: Anna E Odom, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Clarkin JF, Foelsch PA, Levy KN, Hull JW, Delaney JC, Kernberg OF. The development of a psychodynamic treatment for patients with borderline personality disorder: a preliminary study of behavioral change. J Pers Disord. 2001 Dec;15(6):487-95. doi: 10.1521/pedi.15.6.487.19190.
citation: Clarkin JF, Levy KN, Lenzenweger MF, Kernberg OF. Evaluating three treatments for borderline personality disorder: a multiwave study. Am J Psychiatry. 2007 Jun;164(6):922-8. doi: 10.1176/ajp.2007.164.6.922.
citation: Clarkin JF, Levy KN, Lenzenweger MF, Kernberg OF. The Personality Disorders Institute/Borderline Personality Disorder Research Foundation randomized control trial for borderline personality disorder: rationale, methods, and patient characteristics. J Pers Disord. 2004 Feb;18(1):52-72. doi: 10.1521/pedi.18.1.52.32769.