Clinical trial NCT03345836: A Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Biologic Therapy
Official title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Biologic Therapy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Crohn's Disease
Keywords: Upadacitinib
Crohn's Disease
Efficacy
Safety
Lead sponsor: AbbVie
Sponsor class: INDUSTRY
First posted: 2017-11-17
Enrollment: 624
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The objective of this study is to evaluate the efficacy and safety of upadacitinib compared to placebo as induction therapy in participants with moderately and severely active Crohn's disease (CD).


Eligibility criteria: Inclusion Criteria:

* Confirmed diagnosis of CD for at least 3 months prior to Baseline.
* Confirmed diagnosis of moderate to severe CD as assessed by stool frequency (SF), abdominal pain (AP) score.
* Evidence of mucosal inflammation based on the Simplified Endoscopic Score for Crohn's disease (SES-CD) on an endoscopy confirmed by a central reader.
* Demonstrated an inadequate response or intolerance to any biologic therapy for infliximab, adalimumab, certolizumab pegol, vedolizumab, and ustekinumab.
* If female, participant must meet the contraception recommendations.

Exclusion Criteria:

* Participant with a current diagnosis of ulcerative colitis or indeterminate colitis.
* Participant not on stable doses of CD related antibiotics, oral aminosalicylates, corticosteroids or methotrexate (MTX).
* Participant with the following ongoing known complications of CD: abscess (abdominal or peri-anal), symptomatic bowel strictures, fulminant colitis, toxic megacolon, or any other manifestation that might require surgery while enrolled in the study.
* Participant with ostomy or ileoanal pouch.
* Participant diagnosed with conditions that could interfere with drug absorption including but not limited to short gut or short bowel syndrome.
* Screening laboratory and other protocol pre-specified analyses show abnormal results.

Primary outcomes:
measure: Percentage of Participants With Clinical Remission Per Crohn's Disease Activity Index (CDAI) at Week 12
timeFrame: Week 12
measure: Percentage of Participants With Endoscopic Response at Week 12
timeFrame: Baseline to Week 12
measure: Number of Participants With Adverse Events
timeFrame: From first dose of study drug until 30 days following last dose of study drug (up to approximately 28 weeks)
Secondary outcomes:
measure: Percentage of Participants With Clinical Remission Per Patient-Reported Outcomes (PROs) at Week 12
timeFrame: Baseline to Week 12
measure: Percentage of Participants With Endoscopic Remission at Week 12
timeFrame: Baseline to Week 12
measure: Percentage of Participants Who Discontinued Corticosteroid Use for Crohn's Disease (CD) and Achieved Clinical Remission Per CDAI at Week 12, in Participants Taking Corticosteroids at Baseline
timeFrame: Week 12
measure: Change From Baseline in Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) Total Score at Week 12
timeFrame: Baseline and Week 12
measure: Change From Baseline in Inflammatory Bowel Disease Questionnaire (IBDQ) Total Score at Week 12
timeFrame: Baseline and Week 12
measure: Percentage of Participants Achieving Clinical Response 100 (CR-100) at Week 2
timeFrame: Baseline to Week 2
measure: Percentage of Participants Achieving Clinical Response 100 (CR-100) at Week 12
timeFrame: Baseline to Week 12
measure: Percentage of Participants With Clinical Remission Per Crohn's Disease Activity Index (CDAI) at Week 4
timeFrame: Week 4
measure: Percentage of Participants With Hospitalizations Due to Crohn's Disease (CD) During Part 1 (12-week Double-blind Induction Period)
timeFrame: Up to Week 12 in Part 1: Double-blind Induction Period
measure: Percentage of Participants With Resolution of Extra-Intestinal Manifestations (EIMs) at Week 12, in Participants With EIMs at Baseline
timeFrame: Week 12
Other outcomes:
Locations:
city: Mobile
country: United States
facility: East View Medical Research, LLC /ID# 171133
state: Alabama
city: Mobile
country: United States
facility: CB Flock Research Corporation /ID# 166220
state: Alabama
city: Chandler
country: United States
facility: Delsol Research Management, Ll /Id# 170179
state: Arizona
city: Scottsdale
country: United States
facility: HonorHealth Research Institute - Shea /ID# 164734
state: Arizona
city: Sun City
country: United States
facility: Arizona Arthritis & Rheumatology Research, PLLC /ID# 203891
state: Arizona
city: Coronado
country: United States
facility: Southern California Res. Ctr. /ID# 169654
state: California
city: Covina
country: United States
facility: Citrus Valley Gastroenterology /ID# 166201
state: California
city: Los Alamitos
country: United States
facility: United Medical Doctors /ID# 207452
state: California
city: Los Angeles
country: United States
facility: Gastrointestinal Biosciences Clinical Trials, LLC /ID# 164887
state: California
city: Mission Hills
country: United States
facility: Facey Medical Foundation /ID# 203137
state: California
city: Murrieta
country: United States
facility: United Medical Doctors - Murrieta /ID# 164845
state: California
city: San Diego
country: United States
facility: Ucsd /Id# 164679
state: California
city: San Diego
country: United States
facility: Medical Assoc Research Grp /ID# 169705
state: California
city: San Francisco
country: United States
facility: UCSF Center for Colitis and Crohn's Disease /ID# 202373
state: California
city: San Francisco
country: United States
facility: Univ of California San Francis /ID# 164843
state: California
city: San Pablo
country: United States
facility: Care Access Research /ID# 167766
state: California
city: Colorado Springs
country: United States
facility: Peak Gastroenterology Associates, PC /ID# 170181
state: Colorado
city: Colorado Springs
country: United States
facility: Delta Waves, Inc. /ID# 164872
state: Colorado
city: Wheat Ridge
country: United States
facility: Duplicate_Western States Clinical Research, Inc. /ID# 164895
state: Colorado
city: Hamden
country: United States
facility: Medical Research Center of CT /ID# 164829
state: Connecticut
city: Clearwater
country: United States
facility: Clinical Research of West Florida, Inc /ID# 205825
state: Florida
city: Clearwater
country: United States
facility: Clinical Research of West Florida, Inc /ID# 208117
state: Florida
city: Coral Springs
country: United States
facility: Advanced Research - Coral Springs /ID# 218020
state: Florida
city: Jacksonville
country: United States
facility: Encore Borland-Groover Clinical Research /Id# 203498
state: Florida
city: Maitland
country: United States
facility: Ctr for Advanced Gastroenterol /ID# 165332
state: Florida
city: Miami
country: United States
facility: Crystal Pharmacology Research /ID# 166101
state: Florida
city: Miami
country: United States
facility: Coral Research Clinic /ID# 164657
state: Florida
city: New Port Richey
country: United States
facility: Advanced Research Institute, Inc /ID# 164814
state: Florida
city: Orlando
country: United States
facility: Endoscopic Research, Inc. /ID# 205893
state: Florida
city: Orlando
country: United States
facility: Omega Research Maitland, LLC /ID# 203480
state: Florida
city: Tampa
country: United States
facility: Clinical Research Trials of Florida, Inc. /ID# 203484
state: Florida
city: Tampa
country: United States
facility: AdventHealth Tampa /ID# 171175
state: Florida
city: Macon
country: United States
facility: Gastroenterology Associates of Central Georgia, LLC /ID# 165460
state: Georgia
city: Roswell
country: United States
facility: Gastroenterology Consultants PC - Roswell /ID# 218219
state: Georgia
city: Suwanee
country: United States
facility: Atlanta Gastroenterology Spec /ID# 164780
state: Georgia
city: Chicago
country: United States
facility: University of Chicago Medicine /ID# 165472
state: Illinois
city: Downers Grove
country: United States
facility: DuPage Medical Group /ID# 205303
state: Illinois
city: Evansville
country: United States
facility: MediSphere Medical Research Center /ID# 166209
state: Indiana
city: Indianapolis
country: United States
facility: Indianapolis Gastroenterology /ID# 164837
state: Indiana
city: New Albany
country: United States
facility: Aquiant Research /ID# 205504
state: Indiana
city: Iowa City
country: United States
facility: University of Iowa Hospitals and Clinics /ID# 165330
state: Iowa
city: Crestview Hills
country: United States
facility: Tri-State Gastroenterology /ID# 165484
state: Kentucky
city: Louisville
country: United States
facility: University of Louisville /ID# 168536
state: Kentucky
city: Louisville
country: United States
facility: University of Louisville /ID# 208093
state: Kentucky
city: Houma
country: United States
facility: CroNOLA, LLC /ID# 164722
state: Louisiana
city: New Orleans
country: United States
facility: Nola Research Works, LLC /ID# 164897
state: Louisiana
city: Shreveport
country: United States
facility: Louisana Research Center, LLC /ID# 164659
state: Louisiana
city: Baltimore
country: United States
facility: Johns Hopkins University School of Medicine /ID# 211940
state: Maryland
city: Chevy Chase
country: United States
facility: MGG Group Co, Inc.Chevy Chase Clinical Research /ID# 164835
state: Maryland
city: Columbia
country: United States
facility: Gastro Center of Maryland /ID# 171171
state: Maryland
city: Burlington
country: United States
facility: Lahey Hospital and Medical Center /ID# 214725
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan Health Systems /ID# 164844
state: Michigan
city: Chesterfield
country: United States
facility: Clin Res Inst of Michigan, LLC /ID# 170178
state: Michigan
city: Farmington Hills
country: United States
facility: Digestive Health Associates (DHA) - Farmington Hills /ID# 206099
state: Michigan
city: Troy
country: United States
facility: Center for Digestive Health /ID# 164733
state: Michigan
city: Rochester
country: United States
facility: Mayo Clinic - Rochester /ID# 164868
state: Minnesota
city: Jackson
country: United States
facility: Southern Therapy and Advanced Research (STAR) LLC /ID# 165318
state: Mississippi
city: Omaha
country: United States
facility: Quality Clinical Research Inc. /ID# 170177
state: Nebraska
city: Omaha
country: United States
facility: CHI Health Research Center /ID# 168545
state: Nebraska
city: Las Vegas
country: United States
facility: Las Vegas Medical Research /ID# 168562
state: Nevada
city: Egg Harbor Township
country: United States
facility: AGA Clinical Research Associates, LLC /ID# 164883
state: New Jersey
city: New Brunswick
country: United States
facility: Rutgers Robert Wood Johnson /ID# 166092
state: New Jersey
city: Bronx
country: United States
facility: Montefiore Medical Center - Moses Campus /ID# 166226
state: New York
city: Bronx
country: United States
facility: Advantage Clinical Trials /ID# 168557
state: New York
city: Brooklyn
country: United States
facility: NY Scientific /ID# 164833
state: New York
city: Lake Success
country: United States
facility: NYU Langone Long Island Clinical Research Associates /ID# 164830
state: New York
city: New York
country: United States
facility: The Mount Sinai Hospital /ID# 170172
state: New York
city: New York
country: United States
facility: Columbia Univ Medical Center /ID# 164870
state: New York
city: Rochester
country: United States
facility: Gastro Group of Rochester /ID# 166216
state: New York
city: Staten Island
country: United States
facility: Richmond University Medical Center /ID# 201855
state: New York
city: Charlotte
country: United States
facility: Atrium Health Carolinas Medical Center /ID# 164834
state: North Carolina
city: Charlotte
country: United States
facility: PMG Research of Charlotte /ID# 171170
state: North Carolina
city: Raleigh
country: United States
facility: Wake Radiology UNC REX Healthcare - Raleigh Office /ID# 164663
state: North Carolina
city: Winston-Salem
country: United States
facility: Wake Forest Baptist Medical Center /ID# 201225
state: North Carolina
city: Fargo
country: United States
facility: Plains Clinical Research Center, LLC /ID# 170184
state: North Dakota
city: Cincinnati
country: United States
facility: Consultants for Clinical Research /ID# 164855
state: Ohio
city: Cincinnati
country: United States
facility: University of Cincinnati /ID# 164720
state: Ohio
city: Cleveland
country: United States
facility: Cleveland Clinic Main Campus /ID# 208220
state: Ohio
city: Columbus
country: United States
facility: The Ohio State University /ID# 170174
state: Ohio
city: Columbus
country: United States
facility: Optimed Research, Ltd. /ID# 205618
state: Ohio
city: Dayton
country: United States
facility: Hometown Urgent Care and Resea /ID# 201290
state: Ohio
city: Englewood
country: United States
facility: Dayton Gastroenterology, Inc. /ID# 167624
state: Ohio
city: Mentor
country: United States
facility: Great Lakes Medical Research, LLC /ID# 202007
state: Ohio
city: Oklahoma City
country: United States
facility: Digestive Disease Specialists /ID# 201062
state: Oklahoma
city: Tulsa
country: United States
facility: Options Health Research, LLC /ID# 164737
state: Oklahoma
city: Tulsa
country: United States
facility: Healthcare Research Consultant /ID# 166228
state: Oklahoma
city: Philadelphia
country: United States
facility: University of Pennsylvania /ID# 168402
state: Pennsylvania
city: Philadelphia
country: United States
facility: Thomas Jefferson University /ID# 168014
state: Pennsylvania
city: Charleston
country: United States
facility: Pharmacorp Clinical Trials /ID# 164809
state: South Carolina
city: Greenville
country: United States
facility: Gastroenterology Associates, P.A. of Greenville /ID# 164880
state: South Carolina
city: Rapid City
country: United States
facility: Rapid City Medical Center - GI Research /ID# 201734
state: South Dakota
city: Germantown
country: United States
facility: Gastro One /ID# 164718
state: Tennessee
city: Johnson City
country: United States
facility: East Tennessee Research Institute /ID# 203612
state: Tennessee
city: Nashville
country: United States
facility: Quality Medical Research /ID# 205262
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt University Medical Center /ID# 164846
state: Tennessee
city: Arlington
country: United States
facility: TX Clinical Research Institute /ID# 164848
state: Texas
city: Baytown
country: United States
facility: Inquest Clinical Research /ID# 164865
state: Texas
city: Cedar Park
country: United States
facility: Texas Digestive Disease Consultants /ID# 209952
state: Texas
city: Cedar Park
country: United States
facility: Texas Digestive Disease Consultants /ID# 209802
state: Texas
city: Houston
country: United States
facility: CliniCore International, LLC /ID# 164662
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine - Baylor Medical Center /ID# 164847
state: Texas
city: Houston
country: United States
facility: Centex Studies, Inc. - Houston /ID# 201213
state: Texas
city: Houston
country: United States
facility: GI Specialists of Houston /ID# 202338
state: Texas
city: Lubbock
country: United States
facility: Caprock Gastro Research /ID# 215437
state: Texas
city: San Antonio
country: United States
facility: Clinical Associates in Research Therapeutics of America, LLC /ID# 164863
state: Texas
city: San Antonio
country: United States
facility: Southern Star Research Institute, LLC /ID# 169754
state: Texas
city: Sugar Land
country: United States
facility: Carl R. Meisner Medical Clinic /ID# 201060
state: Texas
city: Tyler
country: United States
facility: Tyler Research Institute, LLC /ID# 168681
state: Texas
city: Victoria
country: United States
facility: Gastro Health & Nutrition - Victoria /ID# 167813
state: Texas
city: Bountiful
country: United States
facility: HP Clinical Research /ID# 164929
state: Utah
city: Ogden
country: United States
facility: Advanced Research Institute /ID# 164866
state: Utah
city: Salt Lake City
country: United States
facility: Duplicate_Care Access Research /ID# 164853
state: Utah
city: West Jordan
country: United States
facility: Velocity Clinical Research - Salt Lake City /ID# 166095
state: Utah
city: Bellevue
country: United States
facility: Washington Gastroenterology Associates /ID# 164721
state: Washington
city: Seattle
country: United States
facility: Virginia Mason - Seattle Orthapedics /ID# 164680
state: Washington
city: Seattle
country: United States
facility: University of Washington /ID# 164875
state: Washington
city: Vancouver
country: United States
facility: The Vancouver Clinic, INC. PS /ID# 164811
state: Washington
city: Milwaukee
country: United States
facility: Froedtert Memorial Lutheran Hospital /ID# 202286
state: Wisconsin
city: Wauwatosa
country: United States
facility: Allegiance Research Specialists /ID# 165321
state: Wisconsin
city: San Isidro
country: Argentina
facility: Cardio Alem /ID# 211284
state: Buenos Aires
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Hospital Italiano de Buenos Aires /ID# 215543
state: Ciuadad Autonoma De Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Gedyt /ID# 210019
state: Ciuadad Autonoma De Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Cemic /Id# 169184
state: Ciuadad Autonoma De Buenos Aires
city: Rosario
country: Argentina
facility: Hospital Provincial del Centenario /ID# 171254
state: Santa Fe
city: Cordoba
country: Argentina
facility: Hospital Privado Univesitario /ID# 169228
city: Concord
country: Australia
facility: Concord Repatriation General Hospital /ID# 171509
state: New South Wales
city: North Mackay
country: Australia
facility: Coral Sea Clinical Research institute /ID# 212987
state: Queensland
city: South Brisbane
country: Australia
facility: Mater Misericordiae Limited /ID# 204908
state: Queensland
city: Adelaide
country: Australia
facility: Royal Adelaide Hospital /ID# 171511
state: South Australia
city: Box Hill
country: Australia
facility: Box Hill Hospital /ID# 203734
state: Victoria
city: Murdoch
country: Australia
facility: Fiona Stanley Hospital /ID# 171510
state: Western Australia
city: Vienna
country: Austria
facility: Klinik Landstrasse /ID# 203437
state: Wien
city: Vienna
country: Austria
facility: Medizinische Universitaet Wien /ID# 169462
state: Wien
city: Salzburg
country: Austria
facility: Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 214467
city: Woluwe-Saint-Lambert
country: Belgium
facility: UCL Saint-Luc /ID# 200297
state: Bruxelles-Capitale
city: Liège
country: Belgium
facility: CHU de Liege Sart Tilman /ID# 200299
state: Liege
city: Godinne
country: Belgium
facility: CHU UCL Namur - site Godinne /ID# 200300
state: Namur
city: Leuven
country: Belgium
facility: Universitair Ziekenhuis Leuven /ID# 200298
state: Vlaams-Brabant
city: Gent
country: Belgium
facility: AZ Sint-Lucas /ID# 200301
city: Banja Luka
country: Bosnia and Herzegovina
facility: University Clinical Centre of the Republic of Srpska /ID# 208050
state: Republika Srpska
city: Tuzla
country: Bosnia and Herzegovina
facility: University Clinical Center Tuzla /ID# 210324
state: Tuzlanski
city: Sarajevo
country: Bosnia and Herzegovina
facility: Clinical Center University of Sarajevo /ID# 203885
city: Sarajevo
country: Bosnia and Herzegovina
facility: Polyclinic and Daily Hospital Dr. Al-Tawil /ID# 217841
city: Goiânia
country: Brazil
facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 166870
state: Goias
city: Curitiba
country: Brazil
facility: Hospital Nossa Senhora das Graças /ID# 166869
state: Parana
city: Porto Alegre
country: Brazil
facility: Hospital de Clinicas de Porto Alegre /ID# 166872
state: Rio Grande Do Sul
city: Botucatu
country: Brazil
facility: Upeclin Fmb - Unesp /Id# 166876
state: Sao Paulo
city: Ribeirão Preto
country: Brazil
facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP /ID# 166874
state: Sao Paulo
city: Santo André
country: Brazil
facility: Faculdade de Medicina do ABC /ID# 208327
state: Sao Paulo
city: Sao Jose Do Rio Preto
country: Brazil
facility: Kaiser Clinica e Hospital Dia /ID# 166873
state: Sao Paulo
city: Plovdiv
country: Bulgaria
facility: UMHAT Kaspela EOOD /ID# 167617
city: Sofia
country: Bulgaria
facility: Duplicate_Second MHAT Sofia /ID# 167618
city: Stara Zagora
country: Bulgaria
facility: MHAT Trakia /ID# 201678
city: Calgary
country: Canada
facility: University of Calgary - Cumming School of Medicine - Adult Cystic Fibrosis Clini /ID# 166963
state: Alberta
city: Edmonton
country: Canada
facility: Allen Whey Khye Lim Professional Corporation /ID# 168041
state: Alberta
city: Edmonton
country: Canada
facility: Covenant Health /ID# 166966
state: Alberta
city: New Westminster
country: Canada
facility: Fraser Clinical Trials Inc /ID# 166957
state: British Columbia
city: Vancouver
country: Canada
facility: GIRI Gastrointestinal Research Institute /ID# 166964
state: British Columbia
city: Halifax
country: Canada
facility: QEII - Health Sciences Centre /ID# 169306
state: Nova Scotia
city: North Bay
country: Canada
facility: Scott Shulman Medicine Professional Corporation /ID# 169064
state: Ontario
city: Oshawa
country: Canada
facility: Taunton Surgical Centre /ID# 168039
state: Ontario
city: Ottawa
country: Canada
facility: The Ottawa Hospital /ID# 212413
state: Ontario
city: Sudbury
country: Canada
facility: Medicor Research Inc /ID# 166967
state: Ontario
city: Vaughan
country: Canada
facility: Toronto Digestive Disease Asso /ID# 166961
state: Ontario
city: Levis
country: Canada
facility: CHAU- Hotel-Dieu de Levis /ID# 166958
state: Quebec
city: Montreal
country: Canada
facility: Crchum /Id# 170121
state: Quebec
city: Montreal
country: Canada
facility: Montreal General Hospital - McGill University Health Center /ID# 170010
state: Quebec
city: Sherbrooke
country: Canada
facility: CIUSSS de l'Estrie - CHUS /ID# 170935
state: Quebec
city: Santiago
country: Chile
facility: Research Group /ID# 203180
state: Region Metropolitana De Santiago
city: Santiago
country: Chile
facility: M y F Estudios Clínicos /ID# 169995
state: Region Metropolitana Santiago
city: Concepción
country: Chile
facility: Hospital Guillermo Grant Benavente de Concepción /ID# 212422
city: Providencia
country: Chile
facility: CTR Estudios Clinicos /ID# 200650
city: Santiago
country: Chile
facility: Hospital Clinico Universidad De Los Andes /ID# 207465
city: Fujian
country: China
facility: Zhongshan Hospital Xiamen University /ID# 204985
state: Anhui
city: Guangzhou
country: China
facility: Sun Yat-sen Memorial Hospital of Sun Yat-sen University /ID# 205226
state: Guangdong
city: Guangzhou
country: China
facility: The Sixth Affiliated Hosp Sun /ID# 204049
state: Guangdong
city: Wuhan
country: China
facility: Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 204096
state: Hubei
city: Nanjing
country: China
facility: Nanjing Drum Tower Hospital /ID# 204869
state: Jiangsu
city: Nanchang
country: China
facility: The First Affiliated Hospital of Nanchang University /ID# 204070
state: Jiangxi
city: Changchun
country: China
facility: The First Hospital of Jilin University /ID# 206867
state: Jilin
city: Shanghai
country: China
facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 204072
state: Shanghai
city: Hangzhou
country: China
facility: The second Affiliated hospital of Zhejiang University school of Medicine /ID# 204078
state: Zhejiang
city: Hangzhou
country: China
facility: Sir Run Run Shaw Hospital,Meical School Zhejiang University /ID# 204068
state: Zhejiang
city: Beijing
country: China
facility: Beijing Friendship Hospital /ID# 204536
city: Changsha
country: China
facility: The Second Hospital Central South University /ID# 204075
city: Guangzhou
country: China
facility: Nanfang Hospital of Southern Medical University /ID# 204074
city: Tianjin
country: China
facility: Duplicate_Tianjin Med Univ General Hosp /ID# 206993
city: Wuhan
country: China
facility: Tongji Hospital Tongji Medical College Huazhong University of Science and Techno /ID# 204069
city: Medellin
country: Colombia
facility: Hospital San Vicente de Paul /ID# 200028
state: Antioquia
city: Medellín
country: Colombia
facility: Hospital Pablo Tobon Uribe /ID# 202405
state: Antioquia
city: Zagreb
country: Croatia
facility: Clinical Hospital Dubrava /ID# 171186
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Klinicki bolnicki centar Sestre milosrdnice /ID# 171190
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Klinicki bolnicki centar Zagreb /ID# 171201
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Poliklinika Solmed /ID# 211518
state: Grad Zagreb
city: Split
country: Croatia
facility: UHC Split /ID# 171206
city: Zadar
country: Croatia
facility: Zadar General Hospital /ID# 205534
city: Hradec Kralove
country: Czechia
facility: Hepato-Gastroenterologie HK, s.r.o. /ID# 171566
city: Praha
country: Czechia
facility: ResTrial s.r.o. /ID# 208652
city: Třebovice
country: Czechia
facility: ARTROSCAN s.r.o. /ID# 171592
city: Frederikssund
country: Denmark
facility: Nordsjaellands Hospital /ID# 200613
state: Hovedstaden
city: Herlev
country: Denmark
facility: Herlev Hospital /ID# 200782
state: Hovedstaden
city: Hvidovre
country: Denmark
facility: Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 200611
state: Hovedstaden
city: Roskilde
country: Denmark
facility: Duplicate_Sjaellands Universitets Hospital /ID# 200783
state: Sjælland
city: Alexandria
country: Egypt
facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 171010
city: Alexandria
country: Egypt
facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 171015
city: Cairo
country: Egypt
facility: Clinical Research Center, Faculty of Medicine, Cairo university /ID# 209557
city: Cairo
country: Egypt
facility: National Hepatology and Tropical Medicine Research Institute /ID# 170990
city: Cairo
country: Egypt
facility: Faculty of Medicine Ain Shams Research Institute- Clinical Research Centre /ID# 209565
city: Cairo
country: Egypt
facility: Air Force Specialized Hospital /ID# 170995
city: Tartu Linn
country: Estonia
facility: Tartu University Hospital /ID# 203140
state: Tartumaa
city: Nice
country: France
facility: Chu de Nice-Hopital L'Archet Ii /Id# 171009
state: Alpes-Maritimes
city: Pierre Benite CEDEX
country: France
facility: HCL - Hôpital Lyon Sud /ID# 171014
state: Auvergne-Rhone-Alpes
city: Pessac CEDEX
country: France
facility: CHU Bordeaux - Hopital Haut Lévêque /ID# 207414
state: Gironde
city: Lille
country: France
facility: CHRU Lille - Hopital Claude Huriez /ID# 206539
state: Hauts-de-France
city: Montpellier CEDEX 5
country: France
facility: Duplicate_Hopital Saint Eloi /ID# 170646
state: Herault
city: Clichy
country: France
facility: Hopital Beaujon /ID# 171011
state: Ile-de-France
city: St. Priest En Jarez
country: France
facility: CHU de SAINT ETIENNE - Hopital Nord /ID# 171018
state: Loire
city: Vandœuvre-lès-Nancy
country: France
facility: CHRU Nancy - Hôpitaux de Brabois /ID# 170985
state: Meurthe-et-Moselle
city: Amiens CEDEX 1
country: France
facility: CHU Amiens-Picardie Site Sud /ID# 171016
state: Somme
city: Chambray Les Tours
country: France
facility: CHRU Tours - Hopital Trousseau /ID# 169786
city: Creteil
country: France
facility: Duplicate_CHU Henri Mondor /ID# 169787
city: Nimes Cedex
country: France
facility: Polyclinique Grand Sud /ID# 170649
city: Toulouse
country: France
facility: CHU Toulouse - Hopital Rangueil /ID# 169785
city: Mannheim
country: Germany
facility: Universitatsklinikum Mannheim /ID# 168778
state: Baden-Wuerttemberg
city: Ulm
country: Germany
facility: Universitaetsklinikum Ulm /ID# 203563
state: Baden-Wuerttemberg
city: Erlangen
country: Germany
facility: Universitaetsklinikum Erlangen /ID# 203551
state: Bayern
city: Frankfurt am Main
country: Germany
facility: Universitaetsklinikum Frankfurt /ID# 203565
state: Hessen
city: Saarbrücken
country: Germany
facility: Zentrum für Gastroenterologie Saar MVZ GmbH /ID# 206740
state: Saarland
city: Kiel
country: Germany
facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 168779
state: Schleswig-Holstein
city: Berlin
country: Germany
facility: Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 169067
city: Berlin
country: Germany
facility: Gastroenterologie am Mexikoplatz /ID# 203573
city: Essen
country: Germany
facility: Universitaetsmedizin Essen St. Josef Krankenhaus Werden /ID# 203571
city: Frankfurt am Main
country: Germany
facility: Agaplesion Markus Krankenhaus /ID# 168777
city: Halle (Saale)
country: Germany
facility: Universitaetsklinikum Halle (Saale) /ID# 207454
city: Muenster
country: Germany
facility: Medizinisches Versorgungszentrum Portal 10 /ID# 200213
city: Athens
country: Greece
facility: General Hospital of Athens Ippokratio /ID# 167036
state: Attiki
city: Athens
country: Greece
facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 202103
state: Attiki
city: Piraeus
country: Greece
facility: Tzaneio general hospital of Piraeus /ID# 206432
state: Attiki
city: Heraklion
country: Greece
facility: University General Hospital of Heraklion PA.G.N.I /ID# 167035
state: Kriti
city: Athens
country: Greece
facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 167037
city: Thessaloniki
country: Greece
facility: Genl Hosp Thess Ippokrateio /ID# 208824
city: Hong Kong
country: Hong Kong
facility: Queen Mary Hospital /ID# 171217
city: Miskolc
country: Hungary
facility: CRU Hungary Egeszsegugyi és Szolgaltato Kft. /ID# 205546
state: Borsod-Abauj-Zemplen
city: Gyöngyös
country: Hungary
facility: Bugat Pal Korhaz /ID# 201889
state: Heves
city: Budapest
country: Hungary
facility: Obudai Egeszsegugyi Centrum Kft. /ID# 201891
state: Pest
city: Budapest
country: Hungary
facility: Magyar Honvedseg Egeszsegugyi Kozpont /ID# 201719
city: Debrecen
country: Hungary
facility: Debreceni Egyetem Kenezy Gyula Egyetemi Korhaz /ID# 201720
city: Szekesfehervar
country: Hungary
facility: Mentahaz Maganorvosi Kozpont /ID# 201890
city: Cork
country: Ireland
facility: Mercy University Hospital /ID# 206510
city: Be'er Sheva
country: Israel
facility: Soroka University Medical Center /ID# 169912
state: HaDarom
city: Tel Aviv-Yafo
country: Israel
facility: Tel Aviv Sourasky Medical Center /ID# 204876
state: Tel-Aviv
city: Ashkelon
country: Israel
facility: Barzilai Medical Center /ID# 223372
city: Be'Er Ya'Akov
country: Israel
facility: Assaf Harofeh Medical Center /ID# 204870
city: Jerusalem
country: Israel
facility: Hadassah Medical Center-Hebrew University /ID# 169927
city: Petakh Tikva
country: Israel
facility: Rabin Medical Center /ID# 202635
city: Rehovot
country: Israel
facility: Kaplan Medical Center /ID# 170277
city: Catanzaro
country: Italy
facility: University of Catanzaro /ID# 201920
state: Calabria
city: Rome
country: Italy
facility: Policlinico Universitario Campus Bio-Medico /ID# 168169
state: Lazio
city: Rome
country: Italy
facility: Azienda Ospedaliera San Camillo Forlanini /ID# 168170
state: Lazio
city: Rozzano
country: Italy
facility: Istituto Clinico Humanitas /ID# 168171
state: Milano
city: Rome
country: Italy
facility: Fondazione PTV Policlinico Tor Vergata /ID# 168174
state: Roma
city: Rome
country: Italy
facility: Presidio Columbus-Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Un /ID# 168168
state: Roma
city: Negrar
country: Italy
facility: IRCCS Ospedale Sacro Cuore Don Calabria /ID# 168172
state: Verona
city: Bologna
country: Italy
facility: A.O.U. di Bologna Policlinico S.Orsola-Malpighi /ID# 168173
city: Catania
country: Italy
facility: A.O. Per L'Emergenza Cannizzaro /ID# 168176
city: Genova
country: Italy
facility: Policlinico San Martino/Univer /ID# 168177
city: Milano
country: Italy
facility: ASST Fatebenefratelli Sacco - Ospedale Fatebenefratelli e Oftalmico /ID# 168167
city: Modena
country: Italy
facility: Azienda Ospedaliero-Universitaria di Modena /ID# 200008
city: Palermo
country: Italy
facility: A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 168175
city: Pisa
country: Italy
facility: Azienda Ospedaliero Universitaria Pisana-Stabilimento di Cisanello /ID# 202420
city: Nagakute-shi
country: Japan
facility: Aichi Medical University Hospital /ID# 165957
state: Aichi
city: Nagoya shi
country: Japan
facility: Nagoya City University Hospital /ID# 165956
state: Aichi
city: Nagoyashi
country: Japan
facility: Nagoya University Hospital /ID# 165955
state: Aichi
city: Toyohashi-shi
country: Japan
facility: Toyohashi Municipal Hospital /ID# 200174
state: Aichi
city: Hirosaki-shi
country: Japan
facility: Hirosaki National Hospital /ID# 165944
state: Aomori
city: Sakura-shi
country: Japan
facility: Toho University Sakura Medical Center /ID# 165949
state: Chiba
city: Kurume-shi
country: Japan
facility: Kurume University Hospital /ID# 166004
state: Fukuoka
city: Takasaki-shi
country: Japan
facility: National Hospital Organization Takasaki General Medical Center /ID# 167136
state: Gunma
city: Fukuyama-shi
country: Japan
facility: NHO Fukuyama Medical Center /ID# 167139
state: Hiroshima
city: Hiroshima-shi
country: Japan
facility: Hiroshima University Hospital /ID# 166006
state: Hiroshima
city: Asahikawa-shi
country: Japan
facility: Asahikawa Medical University Hospital /ID# 167133
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 165943
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo Medical University Hospital /ID# 167137
state: Hokkaido
city: Kobe-shi
country: Japan
facility: Aoyama Clinic /ID# 166001
state: Hyogo
city: Nishinomiya-shi
country: Japan
facility: Hyogo College of Medicine College Hospital /Id# 200173
state: Hyogo
city: Kanazawa-shi
country: Japan
facility: Kanazawa University Hospital /ID# 169215
state: Ishikawa
city: Morioka-shi
country: Japan
facility: Iwate Medical University Uchimaru Medical Center /ID# 202407
state: Iwate
city: Kagoshima-shi
country: Japan
facility: Imamura General Hospital /ID# 227136
state: Kagoshima
city: Kagoshima-shi
country: Japan
facility: Idzuro Imamura Hospital /ID# 206651
state: Kagoshima
city: Kagoshima-shi
country: Japan
facility: Sameshima Hospital /ID# 206674
state: Kagoshima
city: Kyoto-shi
country: Japan
facility: Japanese Red Cross Kyoto Daiichi Hosital /ID# 165958
state: Kyoto
city: Kyoto-shi
country: Japan
facility: Kyoto University Hospital /ID# 169888
state: Kyoto
city: Yokkaichi-shi
country: Japan
facility: Yokkaichi Hazu Medical Center /ID# 167191
state: Mie
city: Sendai-shi
country: Japan
facility: Tohoku University Hospital /ID# 167135
state: Miyagi
city: Kashihara-shi
country: Japan
facility: Nara Medical University Hospital /ID# 169216
state: Nara
city: Yamatotakada-shi
country: Japan
facility: Kenseikai Dongo Hospital /ID# 208103
state: Nara
city: Niigata-shi
country: Japan
facility: Niigata University Medical & Dental Hospital /ID# 170044
state: Niigata
city: Oita-shi
country: Japan
facility: Ishida Clinic of IBD and Gastroenterology /ID# 167134
state: Oita
city: Kurashiki-shi
country: Japan
facility: Chikuba Hospital for Proctological and Gastrointestinal Diseases /ID# 166002
state: Okayama
city: Okayama-shi
country: Japan
facility: Okayama University Hospital /ID# 167355
state: Okayama
city: Osaka-shi
country: Japan
facility: Kinshukai Infusion Clinic /ID# 218871
state: Osaka
city: Osaka-shi
country: Japan
facility: Osaka City University Hospital /ID# 166007
state: Osaka
city: Suita-shi
country: Japan
facility: Osaka University Hospital /ID# 169662
state: Osaka
city: Takatsuki-shi
country: Japan
facility: Osaka Medical and Pharmaceutical University Hospital /ID# 206324
state: Osaka
city: Saitama-shi
country: Japan
facility: Tokitokai Tokito clinic /ID# 165945
state: Saitama
city: Otsu-shi
country: Japan
facility: Shiga University of Medical Science Hospital /ID# 167141
state: Shiga
city: Sunto-gun
country: Japan
facility: NHO Shizuoka Medical Center /ID# 167138
state: Shizuoka
city: Bunkyo-ku
country: Japan
facility: Tokyo Medical And Dental University, Medical Hospital /ID# 165948
state: Tokyo
city: Hachioji-shi
country: Japan
facility: Duplicate_Tokai University Hachioji Hospital /ID# 165951
state: Tokyo
city: Minato-ku
country: Japan
facility: The Jikei University Hospital /ID# 167142
state: Tokyo
city: Mitaka-shi
country: Japan
facility: Kyorin University Hospital /ID# 165950
state: Tokyo
city: Shinjuku-ku
country: Japan
facility: Tokyo Women's Medical University Hospital /ID# 205981
state: Tokyo
city: Toyama-shi
country: Japan
facility: Toyama Prefectural Central Hospital /ID# 217833
state: Toyama
city: Wakayama-shi
country: Japan
facility: Japanese Red Cross Wakayama Medical Center /ID# 200638
state: Wakayama
city: Wakayama-shi
country: Japan
facility: Wakayama Medical University Hospital /ID# 169481
state: Wakayama
city: Yamagata-shi
country: Japan
facility: Yamagata University Hospital /ID# 200156
state: Yamagata
city: Guri
country: Korea, Republic of
facility: Hayang University GuriHospital /ID# 167578
state: Gyeonggido
city: Seongnam si
country: Korea, Republic of
facility: CHA University Bundang Medical Center /ID# 167583
state: Gyeonggido
city: Seoul
country: Korea, Republic of
facility: Kangbuk Samsung Hospital /ID# 167577
state: Seoul Teugbyeolsi
city: Seoul
country: Korea, Republic of
facility: Yonsei University Health System Severance Hospital /ID# 167581
state: Seoul Teugbyeolsi
city: Busan
country: Korea, Republic of
facility: Inje University Haeundae Hospital /ID# 202629
city: Busan
country: Korea, Republic of
facility: Dong-A University Hospital /ID# 167582
city: Busan
country: Korea, Republic of
facility: Pusan National University Hospital /ID# 167580
city: Daegu
country: Korea, Republic of
facility: Kyungpook National Univ Hosp /ID# 207015
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center /ID# 167579
city: Seoul
country: Korea, Republic of
facility: Chung-Ang University Hostipal /ID# 207017
city: Riga
country: Latvia
facility: Pauls Stradins Clinical University Hospital /ID# 169493
city: Riga
country: Latvia
facility: Digestive Disease Center Gastro /ID# 169517
city: Riga
country: Latvia
facility: Riga East Clinical University Hospital /ID# 169496
city: Kaunas
country: Lithuania
facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 207263
city: Vilnius
country: Lithuania
facility: Vilnius University Hospital Santaros Klinikos /ID# 203285
city: Alor Setar
country: Malaysia
facility: Hospital Sultanah Bahiyah /ID# 202627
state: Kedah
city: Kuala Lumpur
country: Malaysia
facility: Universiti Kebangsaan Malaysia (UKM) Medical Centre /ID# 170778
state: Selangor
city: Victoria de Durango
country: Mexico
facility: Instituto de Investigaciones Aplicadas a la Neurociencias A.C. /ID# 207143
state: Durango
city: Leon
country: Mexico
facility: Morales Vargas Centro de Investigacion S.C. /ID# 203495
state: Guanajuato
city: Guadalajara
country: Mexico
facility: Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 206779
state: Jalisco
city: Nijmegen
country: Netherlands
facility: Radboud Universitair Medisch Centrum /ID# 166925
state: Gelderland
city: Heerlen
country: Netherlands
facility: Zuyderland Medisch Centrum /ID# 169698
state: Limburg
city: Amsterdam
country: Netherlands
facility: Academisch Medisch Centrum /ID# 166924
city: Enschede
country: Netherlands
facility: Medisch Spectrum Twente /ID# 170297
city: Wroclaw
country: Poland
facility: Vistamed /ID# 208570
state: Dolnoslaskie
city: Krakow
country: Poland
facility: Malopolskie Centrum Kliniczne /ID# 202166
state: Malopolskie
city: Warsaw
country: Poland
facility: WIP Warsaw IBD Point Profesor Kierkus /ID# 224300
state: Mazowieckie
city: Warsaw
country: Poland
facility: Centrum Medyczne Reuma Park w Warszawie /ID# 200488
state: Mazowieckie
city: Warszawa
country: Poland
facility: Centrum Zdrowia MDM /ID# 200486
state: Mazowieckie
city: Guimaraes
country: Portugal
facility: Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 170225
state: Braga
city: Lisbon
country: Portugal
facility: Hospital Egas Moniz /ID# 170249
state: Porto
city: Ponte de Lima
country: Portugal
facility: Unidade Local de Saúde do Alto Minho, EPE - Hospital Conde de Bertiandos /ID# 200606
state: Viana Do Castelo
city: Almada
country: Portugal
facility: Hospital Garcia de Orta, EPE /ID# 170234
city: Porto
country: Portugal
facility: Centro Hospitalar Universitario de Sao Joao, EPE /ID# 170231
city: San Juan
country: Puerto Rico
facility: Mindful Medical Research /ID# 203357
city: San Juan
country: Puerto Rico
facility: School of Medicine University of Puerto Rico-Medical Science Campus /ID# 166770
city: Sector 2
country: Romania
facility: Institutul Clinic Fundeni /ID# 167826
state: Bucuresti
city: Cluj-Napoca
country: Romania
facility: Clinica GASTRO MED SRL /ID# 206367
state: Cluj
city: Timișoara
country: Romania
facility: Cabinet Particular Policlinic Algomed /ID# 167827
city: Kaliningrad
country: Russian Federation
facility: Immanuel Kant Baltic Federal University /ID# 202128
state: Kaliningradskaya Oblast
city: Novosibirsk
country: Russian Federation
facility: LLC Medical Center /ID# 209233
state: Novosibirskaya Oblast
city: Perm
country: Russian Federation
facility: Perm Clinical Center of the Federal Medical and Biological Agency /ID# 202988
state: Permskiy Kray
city: Pyatigorsk
country: Russian Federation
facility: LLC Novaya Klinika /ID# 206615
state: Stavropol Skiy Kray
city: Stavropol
country: Russian Federation
facility: Professor Pasechnikov Gastroenterology and Pankreatology clinic /ID# 202995
state: Stavropol Skiy Kray
city: Kazan
country: Russian Federation
facility: Kazan State Medical University /ID# 169574
state: Tatarstan, Respublika
city: Moscow
country: Russian Federation
facility: Olla-Med Clinic /ID# 208721
city: Murmansk
country: Russian Federation
facility: P.A. Bayandin Murmansk Regiona /ID# 169575
city: Petrozavodsk
country: Russian Federation
facility: Republican hospital named after V.A. Baranov /ID# 206487
city: Pushkin
country: Russian Federation
facility: Euromedservice /ID# 206609
city: Saint Petersburg
country: Russian Federation
facility: X7 Clinical Research Center /ID# 216349
city: St. Petersburg
country: Russian Federation
facility: City Clinical Hospital No. 31 /ID# 208870
city: Belgrade
country: Serbia
facility: Clinical Hosp Center Zvezdara /ID# 168221
state: Beograd
city: Belgrade
country: Serbia
facility: Military Medical Academy /ID# 168784
state: Beograd
city: Belgrade
country: Serbia
facility: University Clinical Center Serbia /ID# 168220
state: Beograd
city: Belgrade
country: Serbia
facility: Clin Hosp Ctr Bezanijska Kosa /ID# 168799
state: Beograd
city: Kragujevac
country: Serbia
facility: University Clinical Center Kragujevac /ID# 205858
state: Sumadijski Okrug
city: Novi Sad
country: Serbia
facility: Clinical Center Vojvodina /ID# 168222
state: Vojvodina
city: Singapore
country: Singapore
facility: KL Ling Gastroenterology and Liver Clinic /ID# 217963
city: Singapore
country: Singapore
facility: Gleneagles Medical Centre /ID# 206530
city: Singapore
country: Singapore
facility: Tan Tock Seng Hospital /ID# 203159
city: Banska Bystrica
country: Slovakia
facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 169952
city: Nitra
country: Slovakia
facility: KM Management, spol. s.r.o. /ID# 170199
city: Ljubljana
country: Slovenia
facility: Univ Medical Ctr Ljubljana /ID# 211042
city: Bloemfontein
country: South Africa
facility: Farmovs (Pty) Ltd /Id# 207536
state: Free State
city: Johannesburg
country: South Africa
facility: Lenasia Clinical Trial Centre /ID# 205144
state: Gauteng
city: Johannesburg
country: South Africa
facility: Wits Clinical Research Site /ID# 170851
state: Gauteng
city: Cape Town
country: South Africa
facility: Dr JP Wright /ID# 170885
state: Western Cape
city: Cape Town
country: South Africa
facility: Private Practice Dr MN Rajabally /ID# 169852
state: Western Cape
city: Santander
country: Spain
facility: Hospital Unversitario Marques de Valdecilla /ID# 202039
state: Cantabria
city: Palma de Mallorca
country: Spain
facility: Hospital Universitari Son Espases /ID# 201997
state: Illes Balears
city: Las Palmas de Gran Canaria
country: Spain
facility: Hospital Universitario Dr. Negrin /ID# 171238
state: Las Palmas
city: Pamplona
country: Spain
facility: Complejo Hospitalario de Navarra /ID# 202038
state: Navarra
city: A Coruna
country: Spain
facility: Hospital Universitario A Coruna - CHUAC /ID# 203908
city: Barcelona
country: Spain
facility: Hospital Universitario Vall d'Hebron /ID# 171237
city: Barcelona
country: Spain
facility: Hospital Clinic de Barcelona /ID# 171242
city: Girona
country: Spain
facility: Hospital Universitario de Girona Doctor Josep Trueta /ID# 202040
city: Huelva
country: Spain
facility: Hospital Juan Ramon Jimenez /ID# 171243
city: Madrid
country: Spain
facility: Hospital Universitario La Paz /ID# 171241
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Macarena /ID# 171240
city: Valencia
country: Spain
facility: Hospital Universitario y Politecnico La Fe /ID# 201988
city: Halmstad
country: Sweden
facility: Hallands Hospital Halmstad /ID# 170840
state: Hallands Lan
city: Alingsas
country: Sweden
facility: Alingsas lasarett /ID# 170838
state: Vastra Gotalands Lan
city: Boras
country: Sweden
facility: Sodra Alvsborgs sjukhus /ID# 202889
state: Vastra Gotalands Lan
city: Gothenburg
country: Sweden
facility: Sahlgrenska University Hospital /ID# 169031
state: Vastra Gotalands Lan
city: Zürich
country: Switzerland
facility: Universitätsspital Zürich /ID# 170999
state: Zuerich
city: Bern
country: Switzerland
facility: Inselspital, Universitätsspital Bern /ID# 171006
city: Taipei City
country: Taiwan
facility: National Taiwan University Hospital /ID# 169789
city: Taoyuan City
country: Taiwan
facility: Linkou Chang Gung Memorial Ho /ID# 169788
city: Kadikoy
country: Turkey
facility: Acibadem Kozyatagi Hospital /ID# 209405
state: Istanbul
city: Melikgazi
country: Turkey
facility: Erciyes University Medical Fac /ID# 171321
state: Kayseri
city: Ankara
country: Turkey
facility: Ankara Univ Medical Faculty /ID# 206412
city: Battalgazi/malatya
country: Turkey
facility: Inonu Universitesi Turgut Ozal /ID# 201267
city: Hatay
country: Turkey
facility: Mustafa Kemal University Medic /ID# 171318
city: Istanbul
country: Turkey
facility: Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty /ID# 200280
city: Istanbul
country: Turkey
facility: Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 171316
city: Mersin
country: Turkey
facility: Mersin University Medical /ID# 171320
city: Sisli
country: Turkey
facility: Sisli Etfal Train & Res Hosp /ID# 171317
city: Yenimahalle
country: Turkey
facility: Gazi Universitesi Tip Fakultes /ID# 217443
city: Belfast
country: United Kingdom
facility: South Eastern Health and Social Care Trust /ID# 205322
state: Antrim
city: Warrington
country: United Kingdom
facility: Warrington and Halton Hospitals NHS Foundation Trust /ID# 171388
state: Cheshire West And Chester
city: Warrington
country: United Kingdom
facility: Warrington and Halton Hospitals NHS Foundation Trust /ID# 209085
state: Cheshire West And Chester
city: London
country: United Kingdom
facility: Barts Health NHS Trust /ID# 218829
state: London, City Of
city: Bath
country: United Kingdom
facility: Royal United Hospitals Bath /ID# 169084
city: Birmingham
country: United Kingdom
facility: University Hospitals Birmingham NHS Foundation Trust /ID# 169080
city: Dudley
country: United Kingdom
facility: The Dudley Group NHS Foundation Trust /ID# 169079
city: Harrow
country: United Kingdom
facility: London North West University Healthcare NHS Trust /ID# 169078
city: London
country: United Kingdom
facility: King's College Hospital NHS Foundation Trusts /ID# 169082
city: Newcastle Upon Tyne
country: United Kingdom
facility: The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 169085
city: Stockport
country: United Kingdom
facility: Stockport NHS foundation trust /ID# 208718
city: Taunton
country: United Kingdom
facility: Taunton and Somerset NHS Foundation Trust /ID# 209664
city: Tooting
country: United Kingdom
facility: St George's University Hospitals NHS Foundation Trust /ID# 205551
city: Wolverhampton
country: United Kingdom
facility: The Royal Wolverhampton NHS Trust /ID# 171387
Study officials:
affiliation: AbbVie
name: ABBVIE INC.
role: STUDY_DIRECTOR
References: