Clinical trial NCT06909851: Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block
Official title: Comparison of the Effectiveness of Adductor Canal Block and Genicular Nerve Block on Postoperative Pain and Analgesic Use in Arthroscopic Knee Surgeries
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Opioid Use
Pain Postoperative
Arthroscopic Knee Surgeries
Keywords: Genicular Nerve Block
Arthroscopic Knee Surgery
Adductor Canal Block
Postoperative Analgesia
Lead sponsor: Başakşehir Çam & Sakura City Hospital
Sponsor class: OTHER_GOV
First posted: 2025-04-04
Enrollment: 68
Sex: ALL
Minimum age (years): 18
Maximum age (years): 72
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Patients who are admitted to the orthopedic and traumatology clinic and are scheduled for arthroscopic knee surgery will be informed and monitored prior to the operation under spinal anesthesia. Preoperatively, either Adductor Canal Block (ACB) (Group A) or Genicular Nerve Block (GNB) (Group B) will be applied. Randomization will be performed using a computer-based method (http://www.randomizer.org) with a 1:1 allocation.
Primary purpose: PREVENTION

Brief summary: This prospective randomized study aims to compare the analgesic efficacy of Adductor Canal Block (ACB) and Genicular Nerve Block (GNB) groups to relieve postoperative pain in participants between ages of 18-72 undergoing arthroscopic knee surgery under spinal anesthesia. The main question it aims to answer is:

To demonstrate whether Adductor Canal Block or Genicular Nerve Block is more effective in postoperative analgesia in patients undergoing arthroscopic knee surgery based on pain scores, opioid consumption and patient satisfaction.

Arthroscopic knee surgeries cause severe pain especially with movement in the post-operative period. After surgery, the movements of the participants are severely restricted because of pain, which increases the possibility of complications and postpones post-operative knee exercises. In this study, the participants' pain status, VAS score, opioid consumption and patient satisfaction will be measured with a simple scoring system for 24 hours at predetermined time points and then compared. Both types of blocks have pain-relieving effects. This study will only investigate which one is more effective in reducing pain, and there will be no deficiency in relieving the pain of the participants.


Eligibility criteria: Inclusion Criteria:

* Voluntary willingness to participate in the study.
* Patients undergoing arthroscopic knee surgery (meniscus, ACL, arthroscopic intervention etc).
* ASA I-II-III classification.
* Aged between 18-72 years.
* No contraindications for regional anesthesia, and deemed suitable for regional anesthesia by the anesthesiologist.
* Undergoing surgery under spinal anesthesia.
* Fully oriented and able to cooperate.

Exclusion Criteria:

* Undergoing surgery under general anesthesia.
* Chronic analgesic use.
* Presence of an active infection at the procedure site.
* Outside the appropriate age range.
* Inability to comply with postoperative pain/NRS follow-ups.
* ASA IV-V classification.
* Non-voluntary patients.
* Pregnancy.

Primary outcomes:
measure: Effectiveness on Pain Scores (NRS)
timeFrame: Postoperative 24 hours
Secondary outcomes:
measure: Amount of rescue analgesia administration
timeFrame: Postoperative 24 hours.
measure: Postoperative Blood pressure
timeFrame: Postoperative 24 hours
measure: Length of hospital stay
timeFrame: Postoperative 14 days
measure: First Time Of Mobilisation/Exercise
timeFrame: Postoperative 24 hours
measure: The Time of Rescue Analgesic
timeFrame: Postoperative 24 hours
measure: Postoperative heart rate
timeFrame: Postoperative 24 hours
measure: Postoperative oxygen saturation levels
timeFrame: Postoperative 24 hours
Other outcomes:
Locations:
city: İ̇stanbul
country: Turkey
facility: Başakşehir Çam & Sakura City Hospital
Study officials:
References:
citation: Vora MU, Nicholas TA, Kassel CA, Grant SA. Adductor canal block for knee surgical procedures: review article. J Clin Anesth. 2016 Dec;35:295-303. doi: 10.1016/j.jclinane.2016.08.021. Epub 2016 Oct 11.
citation: Tamam A, Guven Kose S, Kose HC, Akkaya OT. Comparison of the Effectiveness of Ultrasound-Guided Proximal, Mid, or Distal Adductor Canal Block after Knee Arthroscopy. Turk J Anaesthesiol Reanim. 2023 Apr;51(2):135-142. doi: 10.5152/TJAR.2023.22225.