Clinical trial NCT00524251: The Effect of Lifestyle-Adjustments Prior to Medical Treatment on the Effect of Medical Treatment in Reflux Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: GERD
Quality of Life
Keywords: Patients with reflux complaints
GERD
quality of life
lifestyle adjustments
Lead sponsor: AstraZeneca
Sponsor class: INDUSTRY
First posted: 2007-09-03
Enrollment: 990
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Time perspective: PROSPECTIVE

Brief summary: The purpose of this study is to determine whether the improvement in the quality of life after an initial treatment with esomeprazole 40mg for reflux disease is the same in patients who have already made lifestyle-adjustments as in patients who have not implemented lifestyle-adjustments prior to the start of treatment (baseline)


Eligibility criteria: Inclusion Criteria:

* Patients with reflux complaints
* 18 years of age

Exclusion Criteria:

* Restrictions as mentioned in the registration text
* H2RA or PPI use in the month prior to inclusion

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Almere
country: Netherlands
facility: Research Site
city: Apeldoorn
country: Netherlands
facility: Research Site
city: Baarn
country: Netherlands
facility: Research Site
city: Bennebroek
country: Netherlands
facility: Research Site
city: Blaardingen
country: Netherlands
facility: Research Site
city: Boekel
country: Netherlands
facility: Research Site
city: Bunschoten Spakenburg
country: Netherlands
facility: Research Site
city: Delft
country: Netherlands
facility: Research Site
city: Den Haag
country: Netherlands
facility: Research Site
city: Enschede
country: Netherlands
facility: Research Site
city: Ewijk
country: Netherlands
facility: Research Site
city: Geleen
country: Netherlands
facility: Research Site
city: Haelen
country: Netherlands
facility: Research Site
city: Halfweg NH
country: Netherlands
facility: Research Site
city: Hardenberg
country: Netherlands
facility: Research Site
city: Heemstede
country: Netherlands
facility: Research Site
city: Hillegom
country: Netherlands
facility: Research Site
city: Hilversum
country: Netherlands
facility: Research Site
city: Horst
country: Netherlands
facility: Research Site
city: Kerkrade
country: Netherlands
facility: Research Site
city: Klimmen
country: Netherlands
facility: Research Site
city: Landgraaf
country: Netherlands
facility: Research Site
city: Laren
country: Netherlands
facility: Research Site
city: Leusden
country: Netherlands
facility: Research Site
city: Lichtenvoorde
country: Netherlands
facility: Research Site
city: Lisse
country: Netherlands
facility: Research Site
city: Maastricht
country: Netherlands
facility: Research Site
city: Monster
country: Netherlands
facility: Research Site
city: Nieuw Vennep
country: Netherlands
facility: Research Site
city: Nieuwegein
country: Netherlands
facility: Research Site
city: Nijverdal
country: Netherlands
facility: Research Site
city: Ochten
country: Netherlands
facility: Research Site
city: Oisterwijk
country: Netherlands
facility: Research Site
city: Oldenzaal
country: Netherlands
facility: Research Site
city: Pijnacker
country: Netherlands
facility: Research Site
city: Rijnsburg
country: Netherlands
facility: Research Site
city: Rijssen
country: Netherlands
facility: Research Site
city: s-Gravenzande
country: Netherlands
facility: Research Site
city: Schijndel
country: Netherlands
facility: Research Site
city: Sittard
country: Netherlands
facility: Research Site
city: Soest
country: Netherlands
facility: Research Site
city: Susteren
country: Netherlands
facility: Research Site
city: Swalmen
country: Netherlands
facility: Research Site
city: Tilburg
country: Netherlands
facility: Research Site
city: Vaals
country: Netherlands
facility: Research Site
city: Valkenburg
country: Netherlands
facility: Research Site
city: Veenendaall
country: Netherlands
facility: Research Site
city: Velp
country: Netherlands
facility: Research Site
city: Warnsveld
country: Netherlands
facility: Research Site
city: Wassenaar
country: Netherlands
facility: Research Site
city: Westerhaar-Vrienzenv Wijk
country: Netherlands
facility: Research Site
city: Zandvoort
country: Netherlands
facility: Research Site
city: Zevenhuizen
country: Netherlands
facility: Research Site
city: Zoetermeer
country: Netherlands
facility: Research Site
Study officials:
affiliation: AstraZeneca
name: A Sellink, MD
role: STUDY_DIRECTOR
affiliation: AstraZeneca
name: N van den Berk
role: STUDY_CHAIR
References: