Clinical trial NCT03701971: Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis
Official title: Randomized Prospective Open-label Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pruritus
Lead sponsor: University Hospital, Brest
Sponsor class: OTHER
First posted: 2018-10-10
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: evaluation of the benefit of music therapy on pruritus in patients with pruritic dermatitis compared to the application of an emollient
Primary purpose: OTHER

Brief summary: Many clinical studies have shown the benefit of music therapy in various pathologies, including pain, and it is now established that the latter has a complementary therapeutic interest. Its most frequently identified indications are the fight against acute or chronic pains, the reduction of anxiety, depression and stress, as well as memory disorders such as Alzheimer's disease.

The main modes of action of music therapy involve sensory, cognitive, psychological and behavioral processes that are also found in pruritus.

Pruritus is defined as "an uncomfortable sensation causing the need to scratch. It has similarities with pain but also differences: relief by heat / cold, scratching / withdrawal behavior, localization on the skin, semi-mucous / ubiquitous ... etc.

The pathophysiology also has similarities, pruritus is born at the dermal-epidermal junction at the level of specific cutaneous receptors then follows the classical pathways through a 1st neuron, then the dorsal horn of the spinal cord and a second neuron. At the cerebral level, there is no single center of pruritus but several motor and sensory areas involved.

The similarities suggest that music therapy may have an interest in the management of chronic pruritus, especially since classical treatments (antihistamines, topical corticosteroids) have only partial efficacy in some dermatoses


Eligibility criteria: Inclusion Criteria:

* At least 18 years of age
* Patient with pruritic dermatosis whatever the etiology (psoriasis, atopic dermatitis, toxiderma, cutaneous lymphoma, chronic urticaria ...)
* Hospitalized in continuous hospitalization in the Dermatology Department
* Age of dermatosis ≥ 1 month
* Pruritus score ≥ 3/10 by numerical evaluation
* Patient having signed a consent form

Exclusion Criteria:

* Patient under the age of 18
* Major impairment of hearing function
* Presence of major cognitive disorders
* Refusal to participate
* Pregnant or lactating women
* Institutionalized or emergency patients
* Patient under legal protection regime
* Patient not affiliated to the social security system

Primary outcomes:
measure: Variation in the intensity of pruritus
timeFrame: Hour 0 / Hour 1
Secondary outcomes:
measure: To study the effect of music therapy on the patient's anxiety
timeFrame: Hour 0 / Hour 1
measure: To study the effect of music therapy according to the etiology of pruritus
timeFrame: Hour 0
measure: To study the impact of pruritic dermatitis on the quality of life of the patient
timeFrame: Hour 0
measure: To study the satisfaction of the patients concerning the music session
timeFrame: Hour 1
Other outcomes:
Locations:
city: Brest
country: France
facility: Brest University Hospital
Study officials:
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