Clinical trial NCT04722393: Lung Resection and Pulmonary Rehabilitation
Official title: Outcomes of Pulmonary Rehabilitation After Lung Resection in Patients With Non-Small Cell Lung Cancer
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pulmonary Rehabilitation
Lung Cancer
Keywords: pulmonary rehabilitation
lung surgery
lung cancer
Lead sponsor: Izmir Katip Celebi University
Sponsor class: OTHER
First posted: 2021-01-25
Enrollment: 66
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Pulmonary Rehabilitation Group and Control Group
Primary purpose: TREATMENT

Brief summary: Lung cancer is the most common cancer in the world and surgical resection remains the gold standard curative treatment in early stage non-small cell lung cancer. However, surgery itself is the direct cause of pulmonary function impairment, which dramatically reduces patients tolerance to exercise and their quality of life. Pulmonary rehabilitation (PR) complements surgical treatment and improves patients' exercise and functional capacity, decreases dyspnea, improves health status.

Our aim is to examine the effectiveness of PR applied after lung resection in patients with lung cancer, 2- To determine whether the respiratory exercise training given to patients who could not participate in the PR program is effective.

Detailed description: Pulmonary rehabilitation (PR) is an evidence-based, interdisciplinary, comprehensive exercise program that targets patients with symptomatic chronic respiratory disease. PR integrates exercise and training interventions into a personalized treatment program. PR has become an important component of the general treatment strategy in patients with high-risk surgical diseases such as lung resection. It helps patients return to normal not only physically, but also emotionally and mentally. In patients with lung cancer, preoperative PR increases exercise capacity, decreases post-operative morbidity and mortality. Although it is reported that the PR program applied in the post-operative period increases physical performance and improves the quality of life, referral of patients in need of the PR unit is less than 25%. There is a need to increase the awareness of both pulmonologists and thoracic surgeons about the benefits of the PR program, which is a non-pharmacological and effective intervention.

The investigators have had two objectives in this study. 1- To examine the effectiveness of PR applied after lung resection in patients with lung cancer, 2- To determine whether the respiratory exercise training given to patients who could not participate in the PR program is effective.

An 8-week comprehensive outpatient PR program will applied to half of 66 patients with non-small cell lung cancer who underwent lung resection, and the other half received respiratory exercise training. After the intervention, the results of both groups will compare.

Eligibility criteria: Inclusion Criteria:

* Patients who had undergone surgery for non-small cell lung cancer in the last two years
* Patients who had no chemotherapy or radiotherapy

Exclusion Criteria:

* Patients who were found unsuitable with the cardiology consultation
* Patients with psychiatric problems
* Patients with severe joint diseases
* Reluctant patients

Primary outcomes:
measure: Exercise Capacity
timeFrame: up to 8 weeks
Secondary outcomes:
measure: Respiratory Functions
timeFrame: up to 8 weeks
measure: Dyspnea Sensation
timeFrame: up to 8 weeks
measure: Disease Specific Quality of Life
timeFrame: up to 8 weeks
measure: Anxiety
timeFrame: up to 8 weeks
measure: Depression
timeFrame: up to 8 weeks
measure: Body Mass Index
timeFrame: up to 8 weeks
Other outcomes:
Locations:
city: İzmir
country: Turkey
facility: İlknur Naz Gürşan
Study officials:
References: