Clinical trial NCT03903198: Care Pathways of Acute Heart Failure Patients: Impact on In-hospital Mortality.
Official title: Care Pathways of Acute Heart Failure Patients: Impact on In-hospital Mortality. A French National Prospective Survey
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Acute Heart Failure
Lead sponsor: Association pour le Développement de la Recherche et de l'Enseignement en Médecine d'Urgence
Sponsor class: OTHER
First posted: 2019-04-04
Enrollment: 3677
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients hospitalized in 26 french hospitals for Acute Heart Failure

Brief summary: The investigators conducted a prospective observational study to describe the different pre-hospital and in-hospital pathways of patients with acute heart failure (AHF) and their association with in-hospital mortality.

Detailed description: Prospective observational national multicentric study in 26 centres. Between june 2014 and october 2018 The investigators collected data about baseline characteristics, first recourse, in-hospital places of care and places of hospitalizations. Lengths of care and lengths of hospitalization.

Collected data of each patient were reported on a specific assessment tool. The investigators ran a univariate analysis and logistic regression between steps of the care pathway and in-hospital mortality. The main result was validated by an analysis with a propensity score: association between a hospitalization in cardiology and in-hospital mortality.

Eligibility criteria: Inclusion Criteria:

* All patients presenting to hospital with Acute Heart Failure according to the physician in care

Exclusion Criteria:

-

Primary outcomes:
measure: In-hospital mortality
timeFrame: Between patient's inclusion in the study and it's hospital discharge, up to one year
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Association pour le Développement de la Recherche et de l'Enseignement en Médecine d'Urgence
name: Frederic ADNET, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Cowie MR, Anker SD, Cleland JGF, Felker GM, Filippatos G, Jaarsma T, Jourdain P, Knight E, Massie B, Ponikowski P, Lopez-Sendon J. Improving care for patients with acute heart failure: before, during and after hospitalization. ESC Heart Fail. 2014 Dec;1(2):110-145. doi: 10.1002/ehf2.12021. Epub 2015 Jan 21.
citation: Cleland JG, McDonagh T, Rigby AS, Yassin A, Whittaker T, Dargie HJ; National Heart Failure Audit Team for England and Wales. The national heart failure audit for England and Wales 2008-2009. Heart. 2011 Jun;97(11):876-86. doi: 10.1136/hrt.2010.209171. Epub 2010 Dec 20.
citation: Gorlicki J, Boubaya M, Cottin Y, Angoulvant D, Soulat L, Guinemer S, Bloch-Queyrat C, Deltour S, Lambert Y, Juilliere Y, Adnet F. Patient care pathways in acute heart failure and their impact on in-hospital mortality, a French national prospective survey. Int J Cardiol Heart Vasc. 2019 Dec 5;26:100448. doi: 10.1016/j.ijcha.2019.100448. eCollection 2020 Feb.