Clinical trial NCT01693588: Study of a Multimodality Pain Management Protocol on Postoperative Neurosurgical Pain
Official title: The Effect of a Multimodality Pain Management Protocol on Postoperative Neurosurgical Pain
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pain
Postoperative Pain
Surgical Pain
Neurosurgical Pain
Keywords: Pain
Postoperative Pain
Surgical Pain
Neurosurgical Pain
Lead sponsor: University of Florida
Sponsor class: OTHER
First posted: 2012-09-26
Enrollment: 94
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: High levels of postoperative pain are associated with an increased risk of lung and heart complications, are the most common reason for delayed discharge or for unexpected hospital admission after ambulatory surgery, and are responsible for prolonged recovery after inpatient surgery. Furthermore both neuropathic pain and post surgical pain inhibit weight gain and may have an impact on the patient's nutrition post operatively. The purpose of this study is to evaluate the effectiveness of a multimodality pain management protocol on postoperative neurosurgical pain.

Detailed description: Despite the long-standing recognition of postoperative pain as both prevalent and undertreated, 20% to 30% of all surgical patients continue to experience moderate to severe postoperative pain. High levels of postoperative pain are associated with an increased risk of pulmonary and cardiovascular complications, are the most common reason for delayed discharge or for unexpected hospital admission after ambulatory surgery, and are responsible for prolonged convalescence after inpatient surgery. Furthermore both neuropathic pain and post surgical pain inhibit weight gain and may have an impact on the patient's nutrition post operatively. Finally, high levels of postoperative pain have also been associated with an increased risk of chronic pain. Therefore, the aggressive treatment of postoperative pain may be particularly important in influencing patient outcomes, inadvertent readmissions, and propensity for developing chronic pain.

Eligibility criteria: Inclusion Criteria:

* Postoperative neurosurgical patient treated at the University of Florida
* Primary language is English

Exclusion Criteria:

* Younger than 18 or older than 100 years of age
* Patients who are pregnant, wards of the state, prisoners, and patients who lack the ability to communicate their pain level

Primary outcomes:
measure: Mean Score on the Visual Analogue Scale
timeFrame: Post Operative Day 1
measure: Mean Score on the Visual Analogue Scale
timeFrame: Post Operative Day 3
Secondary outcomes:
measure: Score on the HCAHP survey.
timeFrame: Hospital discharge, an expected average of 5 days.
Other outcomes:
Locations:
city: Gainesville
country: United States
facility: University of Florida
state: Florida
Study officials:
affiliation: University of Florida
name: William L. Titsworth, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Titsworth WL, Abram J, Guin P, Herman MA, West J, Davis NW, Bushwitz J, Hurley RW, Seubert CN. A prospective time-series quality improvement trial of a standardized analgesia protocol to reduce postoperative pain among neurosurgery patients. J Neurosurg. 2016 Dec;125(6):1523-1532. doi: 10.3171/2015.10.JNS15698. Epub 2016 Mar 11.