Clinical trial NCT03210597: Effects of Water-Based Exercise in Women With Metabolic Syndrome
Official title: Effects of Water-Based Aerobic Training, Resistance Training and Concurrent Training in Women With Metabolic Syndrome: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Metabolic Syndrome
Keywords: water-base exercise
Lead sponsor: Federal University of Rio Grande do Sul
Sponsor class: OTHER
First posted: 2017-07-07
Enrollment: 51
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The objective of the present study was to compare the neuromuscular, cardiorespiratory and metabolic effects of 12 weeks of aerobic training, strength training and combined training in the aquatic environment in women with MS. For this purpose, 51 postmenopausal, sedentary and MS women were randomly divided into three intervention groups: hydro-aerobic (HA, n = 18, 63.77 ± 5.03 years), hydro-power (HF, n = 16, 61.01 ± 4.93 years) and hydro-combined (HC; n = 17; 60.52 ± 6.91). A subsample participated in eight weeks without physical exercise to characterize a control period. The three intervention groups performed two weekly sessions of 60 minutes for 12 weeks. Before and after the training period, blood tests, muscle strength tests, cardiorespiratory evaluation, functional tests and a questionnaire were performed. For statistical analysis, the Generalized Estimates Equations (GEE) model was used, using the "group" and the "time" as factors. The Bonferroni post hoc was used to locate the differences and the significance index adopted was α = 0.05.

Detailed description: Water-based exercise as a mode of aquatic exercise has been highlighted in the scientific literature. Research on different models of training, aerobic, muscle strength and combined (aerobic and muscle strength), have already demonstrated their beneficial effects on different physical abilities. Recent studies indicate benefits of water-based exercise for the population with metabolic diseases such as hypertension, type 2 diabetes, dyslipidemias and obesity. However, for subjects with metabolic syndrome (MS) there are few studies that investigated which training model in the aquatic environment could generate physical and metabolic improvements.

This study is characterized as a randomized clinical trial, which treated three intervention groups with physical exercise programs. A subsample participated in a period of eight weeks without physical exercise to characterize a control period. The subjects in this subsample were later randomized into the intervention groups.

Eligibility criteria: Inclusion Criteria:

* Postmenopausal;
* Sedentary;
* Presented at least three positive components within the five possible to characterize the metabolic syndrome.

Exclusion Criteria:

* Smokers.

Primary outcomes:
measure: Systolic and diastolic blood pressure
timeFrame: 12 weeks
Secondary outcomes:
measure: Strength tests: Maximum dynamic muscle strength
timeFrame: 12 weeks
measure: EMG test
timeFrame: 12 weeks
measure: Time Up and go test
timeFrame: 12 weeks
measure: Sit and Stand test
timeFrame: 12 weeks
measure: Triglyceride levels
timeFrame: 12 weeks
measure: HDL cholesterol levels
timeFrame: 12 weeks
measure: Fasting blood glucose levels
timeFrame: 12 weeks
measure: Waist circumference
timeFrame: 12 weeks
Other outcomes:
Locations:
Study officials:
affiliation: Federal Universty of Rio Grande do Sul
name: Luiz F. Martins Kruel
role: STUDY_DIRECTOR
References: