louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT00164177: Evaluation Of The Efficacy Of HalfLYTELY For Bowel Cleansing Before Virtual Colonoscopy and Conventional Colonoscopy.
Official title: A Preliminary Evaluation Of The Efficacy Of HalfLYTELY® For Bowel Cleansing Before Virtual Colonoscopy (VC) and Conventional Colonoscopy (CC).
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Colonoscopy
Keywords: virtual colonoscopy
colonoscopy preparation
bowel prep
Lead sponsor: Braintree Laboratories
Sponsor class: INDUSTRY
First posted: 2005-09-14
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP

Brief summary: To evaluate the efficacy of standard HalfLYTELY® as a bowel cleansing preparation for adult patients undergoing virtual colonoscopy (VC).


Eligibility criteria: Inclusion Criteria:

* Male or female outpatients who are undergoing colonoscopy for routinely accepted indications, Evaluation of BE results, GI bleeding, Anemia of unknown etiology, Neoplastic disease surveillance, Endosonography, Inflammatory bowel disease (except as noted below), Unknown diarrhea etiology, Prior Polypectomy, Laser therapy, Foreign body removal and decompression (except as noted below).
* 18 years of age or older.
* Otherwise in good health, as determined by physical exam and medical history.
* If female, and of child-bearing potential, is using an acceptable form of birth control (hormonal birth control, IUD, double-barrier method, or vasectomized spouse)
* Subject has read and signed the written informed consent document prior to study participation

Exclusion Criteria:

* Subjects with known or suspected bowel perforation or obstruction, inflammatory bowel disease, ileus, acute alimentary tract surgery, significant gastroparesis or gastric outlet obstruction, appendicitis, gastric retention, toxic colitis, toxic megacolon or rectal bleeding.
* Subjects with impaired consciousness that predisposes them to pulmonary aspiration.
* Subjects with uncontrolled cardiovascular disease
* Subjects who, in the opinion of the investigator, should not be included in the study for any reason, including inability to follow study procedures.
* Subjects who have participated in an investigational clinical surgical, drug or device study within the past 30 days.
* Subjects who are pregnant or lactating.
* Subjects who are allergic to Polyethyleneglycol.
* Subjects receiving non-study laxatives, antacids and prokinetic agents during the study.

Primary outcomes:
measure: Efficacy of the preparation to produce a degree of fecal matter and residual liquid that would not interfere with VC or CC.
Secondary outcomes:
measure: Incidence of adverse events.
Other outcomes:
Locations:
city: Vero Beach
country: United States
state: Florida
Study officials:
affiliation: Indian River Radiology
name: H. Paul Hatten, Jr., MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04711577: Examining Self-tracking Behaviors in a Mobile Intervention for Binge Eating and Weight Management
Official title: Examining Self-tracking Behaviors in a Mobile Intervention for Binge Eating and Weight Management
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Obesity
Binge Eating
Lead sponsor: Northwestern University
Sponsor class: OTHER
First posted: 2021-01-15
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The purpose of this study is to understand users' experiences and interests completing self-tracking in a mobile intervention for binge eating and weight management.


Eligibility criteria: Inclusion Criteria:

* Adults age 18 years or older
* Obesity (BMI ≥30)
* Recurrent binge eating (≥12 episodes in the past 3 months)
* Interested in losing weight and reducing binge eating
* Willing to use a mobile application
* Willing to practice self-monitoring
* Has access to a scale
* Not pregnant
* English-speaking

Exclusion Criteria:

* None

Primary outcomes:
measure: Compliance
timeFrame: 3 weeks
measure: Satisfaction with tracking
timeFrame: 3 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Chicago
country: United States
facility: Northwestern University
state: Illinois
Study officials:
References:
Clinical trial NCT06441877: Community Spirit in Residence for the Elderly
Official title: The Elder at the Heart of His or Her Living Environment - Social Participation and Community Spirit in Residence for the Elderly
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Sense of Community
Keywords: sense of community
social participation
sense of belonging
social cohesion
Lead sponsor: TOPMED
Sponsor class: OTHER
First posted: 2024-06-04
Enrollment: 27
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Elderly home care residents and the managers that work on site. The participants will be sampled from the selected community homes.

Brief summary: The objective of our study is to observe and understand factors that emphasizes the creation of a community spirit.

Specific objectives:

1. Explore and understand the facilitators and challenges of social participation in a residential context;
2. Explore and understand the facilitators and challenges of creating a sense of community in a residential setting.


Eligibility criteria: Inclusion Criteria:

For site managers

* Be a manager in the residences concerned
* Be a department manager or
* Hold a General Manager position or
* Be a member of the partner's head office

For residents

* Residents of the autonomous wing of the targeted residences
* Close caregiver of a resident of the residences included in the research project

Exclusion Criteria:

* Neurocognitive disorders
* Significant language difficulties
* Lack of verbal communication

Primary outcomes:
measure: Sense of Community Factors
timeFrame: Up to 1 month after participants' recruitment
measure: Sense of Community
timeFrame: Up to two weeks prior to the interview session
Secondary outcomes:
measure: Sense of Community Facilitators
timeFrame: Up to 1 month after participants' recruitment
measure: Sense of Community Obstacles
timeFrame: Up to 1 month after participants' recruitment
Other outcomes:
Locations:
city: Québec
country: Canada
facility: TOPMED
state: Quebec
Study officials:
References:
Clinical trial NCT05317377: Leap Motion In Geriatric Rehabilitation
Official title: Leap Motion Controller Based Exergame Therapy in Geriatric Individuals
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Elderly
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2022-04-07
Enrollment: 30
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Little is Known about the effects of leap motion based exergame therapy on different functions of elderly adults. The purpose of this study was to evaluate the effect of leap motion based exergame therapy on hand function, cognitive function and quality of life in older adults


Eligibility criteria: Inclusion Criteria:

* 50 years old and over,
* having adequate hand function,
* ability to follow commands,
* 24\< points in MMSE

Exclusion Criteria:

* presence of exercise contraindications
* 14 or more points on the Geriatric Depression Scale
* diagnosis of dementia
* recent (acute) hand or arm injury

Primary outcomes:
measure: Grip Strength Test
timeFrame: changes after 8 weeks
Secondary outcomes:
measure: Pittsburgh Rehabilitation Participation Scale
timeFrame: changes after 8 weeks
measure: World Health Organization Quality of Life Instrument-Older Adults Module
timeFrame: changes after 8 weeks
measure: Digit Span Test
timeFrame: changes after 8 weeks
measure: Duruöz Hand Index
timeFrame: changes after 8 weeks
measure: Stroop Test
timeFrame: changes after 8 weeks
measure: Purdue Pegboard Test
timeFrame: changes after 8 weeks
measure: Box and Block Test
timeFrame: changes after 8 weeks
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medipol University
Study officials:
References:
Clinical trial NCT02465177: Tailoring Screening, Brief Intervention, and Referral to Treatment for Medical ICU Survivors
Official title: Tailoring Screening, Brief Intervention, and Referral to Treatment for Medical Intensive Care Unit Survivors
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Unhealthy Alcohol Use
Alcohol Use Disorders
Keywords: Unhealthy alcohol use
ICU survivors
Alcohol use disorder
SBIRT
Screening, brief intervention, and referral to treatment
Lead sponsor: University of Colorado, Denver
Sponsor class: OTHER
First posted: 2015-06-08
Enrollment: 28
Sex: MALE
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients admitted to one of 3 medical intensive care units in the Denver metropolitan area

Brief summary: Unhealthy alcohol use is present in up to 38% of the 4 million patients admitted to an American intensive care unit (ICU) each year in the US. Despite the high prevalence of unhealthy alcohol use in ICU survivors, routine interventions targeted at reducing alcohol consumption, alcohol-related consequences, and illness related to alcohol are not currently part of the multidisciplinary approach to critical care. Although screening, brief intervention, and referral to treatment (SBIRT) has been described in several healthcare settings, it fails to address common characteristics of medical ICU survivors including high rates of alcohol use disorders, cognitive dysfunction, psychiatric comorbidities, and intimate involvement of friends and family. This study uses a qualitative approach to further understand the needs of medical ICU survivors with unhealthy alcohol use. The investigators hypothesize that there are common, modifiable barriers to improving alcohol-related outcomes


Eligibility criteria: Inclusion Criteria:

* 18 years or older
* admitted to the medical ICU
* resolution of critical illness
* resolution of delirium/agitation
* AUDIT score 8 or greater for men, 5 or greater for women

Exclusion Criteria:

* unable to provide informed consent
* prisoner
* Unable to speak or write in English
* Pregnant

Primary outcomes:
measure: Change in alcohol use
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Aurora
country: United States
facility: University of Colorado Hospital
state: Colorado
Study officials:
References:
Clinical trial NCT00959777: Pharmacokinetic/Pharmacodynamic (PK/PD) Study Evaluating DA-3031 (PEG-G-CSF) to Filgrastim (Dong-A) in Healthy Volunteers
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Healthy Volunteers
Lead sponsor: Dong-A ST Co., Ltd.
Sponsor class: INDUSTRY
First posted: 2009-08-17
Sex: MALE
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT

Brief summary: The safety, tolerability, and pharmacokinetics(PK)/pharmacodynamics (PD) of DA-3031 (PEG-G-CSF) following a single dose delivered by subcutaneous (SC) injection were investigated in healthy volunteers. PK/PD of filgrastim (Dong-A) following repeated dose delivered by SC injection were investigated in healthy volunteers. PK/PD from a single dose of DA-3031 and repeated dose of filgrastim (Dong-A) were compared.


Eligibility criteria: Inclusion Criteria:

* Healthy males subjects, 20-40 years inclusive
* weight 60-75 kg inclusive and Ideal Body Weight (IBW) between -15% and +15% inclusive
* Written informed consent given
* Willing and able to comply with the requirements of the protocol

Exclusion Criteria:

* Hypersensitivity to drugs(aspirin, antibiotics and so on)
* History or presence of any clinically significant liver or kidney disease, gastrointestinal, cardiovascular, respiratory, endocrinal, musculoskeletal, neurologic/psychiatric, hematological, oncological pathology
* Have a history of drug abuse, or show positive for drug abuse at urine screening
* Have participated in another clinical study within 2 months prior to entering inth the study
* Have been persistently drinking alcohol or can not stop drinking alcohol during the study
* Smokers whose average smoke for last 3 months is more than 10 cigarettes/day
* Are considered ineligible by the investigator due to clinical laboratory results or any other relevant reasons

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Clinical Trials center, Clinical Research institute, Seoul National University Hospital
state: Yonggon-Dong, Chongono-Gu
Study officials:
References:
citation: Ahn LY, Shin KH, Lim KS, Kim TE, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS. Relationship between absolute neutrophil count profiles and pharmacokinetics of DA-3031, a pegylated granulocyte colony-stimulating factor (pegylated-G-CSF): a dose block-randomized, double-blind, dose-escalation study in healthy subjects. Clin Drug Investig. 2013 Nov;33(11):817-24. doi: 10.1007/s40261-013-0130-9.
Clinical trial NCT06833177: Clinical Evaluation of Ceramage Inlays Cemented with Beautilink Self-Adhesive Resin Cement Versus Rely X Resin Cement in Carious Posterior Teeth
Official title: Eighteen Months Clinical Evaluation of Hybrid Ceramic Inlays Cemented with Giomer Based Self-adhesive Resin Cement Versus Resin-based Cement in Carious Posterior Teeth: Randomized Controlled Clinical Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Caries Class Ii
Keywords: Inlays
Ceramage
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-02-18
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Minimally invasive bonded partial restorations have become a crucial component of contemporary dental treatments. They address the shortcomings of direct restorations and provide patients with a less damaging alternative to full coverage restorations, which can be more harmful to the dental structure. Indirect inlay composite restorations have become a popular choice in restorative dentistry due to their aesthetic appeal and durability. These restorations allow for the preservation of tooth structure while utilizing the mechanical advantages of modern adhesive technology, which can reinforce the weakened compromised tooth structure.

The use of different adhesive materials with Ceramage can significantly influence the success of the restoration. Adhesive materials play a crucial role in ensuring a strong bond between the indirect restoration and the tooth structure. Additionally, the choice of adhesive material can also affect the ease of the cementation process. Self-adhesive resin cement simplifies the procedure by eliminating the need for separate bonding agents, thus reducing the risk of technique sensitivity which can lead to more consistent clinical outcomes and improved patient satisfaction.

Overall, the combination of Ceramage with appropriate adhesive materials offers a reliable and aesthetically pleasing solution for indirect inlay composite restorations, enhancing both the biological, functional and esthetic outcomes of dental treatments.


Eligibility criteria: Inclusion Criteria:

* Posterior vital tooth with a large carious lesion (ICDAS 4/5)
* Posterior vital tooth with a broken restoration that should be replaced (ICDAS 4-7/5-7).
* Vital, periodontally sound and with positive reaction to cold stimulus.
* Fully erupted posterior molar in normal functional occlusion with natural antagonist and adjacent teeth.

Exclusion Criteria:

* Teeth with clinical symptoms of pulpitis such as spontaneous pain or sensitivity to pressure.
* Non-vital teeth, Fractured or cracked teeth.
* Endodontically treated teeth.
* Periodontally affected teeth.

Primary outcomes:
measure: Clinical Performance assessing Biological, Mechanical and Esthetic Parameters Using Modified USPHS Criteria
timeFrame: T0: 12 months T1: 18 months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT03895177: Evaluation of Resectability of Pancreatic Cancer Using Low kVp CT
Official title: Usefulness of Low kVp High mAs Computed Tomography for the Evaluation of Pancreatic Cancer Resectability
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Diagnoses Disease
Lead sponsor: Seoul National University Hospital
Sponsor class: OTHER
First posted: 2019-03-29
Enrollment: 147
Sex: ALL
Minimum age (years): 20
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: The aim of this study is to investigate usefulness of low kVp high mAs computed tomography in evaluation of pancreatic cancer resectability.


Eligibility criteria: Inclusion Criteria:

* 1. age between 20 year-old and 85 year-old 2. patient with pancreatic cancer detected on standard CT scan using 120 kVp that obtained within one month 3. consider surgical resection for pancreatic cancer treatment 4. patients who can undergo contrast enhanced CT scan

Exclusion Criteria:

* 1. history of severe adverse reaction to iodine contrast 2. less than 60 of estimated GFR

Primary outcomes:
measure: accuracy of low kVp CT to assess R0 resection of pancreatic cancer
timeFrame: 2 weeks after surgery
Secondary outcomes:
Other outcomes:
Locations:
city: Goyang-si
country: Korea, Republic of
facility: Korea National Cancer Center
state: Kyung-gi Do
city: Anyang
country: Korea, Republic of
facility: Hallym University Sacred Heart Hospital
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
city: Seoul
country: Korea, Republic of
facility: Severance Hospital
city: Seoul
country: Korea, Republic of
facility: Asan medical Center
city: Seoul
country: Korea, Republic of
facility: Korea University Guro Hospital
Study officials:
affiliation: Seoul National University Hospital
name: Jeong Min Lee, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05728177: Effect of Inhalation Aromatherapy on Anxiety and Depressive Symptoms of Geriatric Patients With Parkinson's Disease
Official title: Effect of Inhalation Aromatherapy on Anxiety and Depressive Symptoms of Geriatric Patients With Parkinson's Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Inhalation Aromatherapy
Keywords: Inhalation Aromathrapy, Anxiety, Depressive Symptoms, Parkinson's Disease
Lead sponsor: Alexandria University
Sponsor class: OTHER
First posted: 2023-02-15
Enrollment: 60
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The present study aims to:

Investigate the effect of inhalation aromatherapy on anxiety and depressive symptoms of geriatric patients with Parkinson's disease.

Research Hypothesis:

Patients with Parkinson's disease who inhale aromatherapy will exhibit lower anxiety and depressive symptoms than those who didn't inhale it

Detailed description: A sample of 60 randomly selected patients with patients Parkinson's disease was included in this study. The study subjects were divided equally into two groups; study (30 patients) and a control group (30 patients) matched as much as possible. Exclusion criteria included patients diagnosed for Parkinson's by a specialist, no use of any complementary alternative medicine methods (herbal medicines and other methods) in the past one week, no use of anxiolytics or antidepressants drugs, no history of respiratory problems as asthma, eczema and allergies to flowers and plants and no smell disorders. Patients who were not willing to participate, not able to provide written consent or not able to communicate coherently and relevantly or showed symptoms of allergy to lavender were excluded from the study.

Eligibility criteria: Inclusion Criteria:

patients diagnosed for Parkinson's by a specialist

Exclusion Criteria:

no use of any complementary alternative medicine methods (herbal medicines and other methods) in the past one week, no use of anxiolytics or antidepressants drugs, no history of respiratory problems as asthma, eczema and allergies to flowers and plants and no smell disorders. Patients who were not willing to participate, not able to provide written consent or not able to communicate coherently and relevantly or showed symptoms of allergy to lavender will be excluded from the study.

Primary outcomes:
measure: The Beck Depression Inventory (BDI-II)
timeFrame: 2 weeks
Secondary outcomes:
Other outcomes:
measure: Beck Anxiety Inventory (BAI)
timeFrame: 2 weeks
Locations:
city: Alexandria
country: Egypt
facility: Faculty of Nursing
Study officials:
References:
citation: Marsh L. Depression and Parkinson's disease: current knowledge. Curr Neurol Neurosci Rep. 2013 Dec;13(12):409. doi: 10.1007/s11910-013-0409-5.
citation: Tang SK, Tse MY. Aromatherapy: does it help to relieve pain, depression, anxiety, and stress in community-dwelling older persons? Biomed Res Int. 2014;2014:430195. doi: 10.1155/2014/430195. Epub 2014 Jul 13.
Clinical trial NCT05604677: Factor Influencing Breast Surgery Type Decision-Making
Official title: Factors Influencing the Decision-making Process for Breast Surgery in Women Likely to Face Breast Cancer.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Breast Neoplasm
Keywords: Breast Cancer
Mastectomy
Breast Conserving Surgery
Lebanese Population
Surgical Choice
Oncoplastic Surgery
Lead sponsor: Dr Etienne El Helou
Sponsor class: OTHER
First posted: 2022-11-03
Enrollment: 380
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Lebanese Females

Brief summary: The aim of this observational study is to determine the factors influencing the decision-making process for breast surgery type, in Lebanese women likely to face breast cancer.

The main questions it aims to answer are the presence or not of a correlation between the type of choice and the following data:

* Demographic
* Health Status
* Several factors that may influence the decision

Participants will complete a well-structured and organized online survey


Eligibility criteria: Inclusion Criteria:

* Lebanese Females

Exclusion Criteria:

* None

Primary outcomes:
measure: Influencing Factors
timeFrame: 2 months
Secondary outcomes:
Other outcomes:
Locations:
city: Baabda
country: Lebanon
facility: HelouEl
state: Mount Lebanon
Study officials:
affiliation: Dr Etienne El Helou
name: Etienne El-Helou, MD
role: PRINCIPAL_INVESTIGATOR
References: