Clinical trial NCT05099861: Clinical Anatomy of Superficial Veins of Lower Limbs
Official title: Clinical Anatomy of Superficial Veins of Lower Limbs
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Saphenous Vein Injury
Keywords: small saphenous vein
great saphenous vein
saphenopopliteal junction
venae intersaphenae
Lead sponsor: Charles University, Czech Republic
Sponsor class: OTHER
First posted: 2021-10-29
Enrollment: 400
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: European population

Brief summary: The study is focused on clinical anatomy of superficial veins of lower limbs. We are mapping their anatomy via ultrasonography. We are focusing on saphenopopliteal junction and communicants between small saphenous vein and great saphenous vein.

Detailed description: Research project is focused on superficial veins of lower extremities, especially their clinical anatomy. Superficial veins are located within the compartimentum saphenum. The function of superficial veins is drainage of intradermal and epifascial spaces. Superficial veins and their function are fundamental in development of chronic venous disorder. These veins are physiologically connected with deep venous system via perforators but also between each other via communicanting veins. Communicanting veins between small saphenous vein and great saphenous vein have not been described yet, particularly because of their variations. Clinically important is also the saphenopopliteal junction in the fossa poplitea. This region features many variations, which were described in many studies. Also, the nomenclature of saphenopopliteal juction is not standardised in comparison to the saphenofemoral junction. Moreover, many articles are pointing out that there were not specified all potential drainage ways of the cranial extension of small saphenous vein (extesio cranialis). Articles are uniform neither in its prevalence nor in its terminology.

The knowledge of connections between the superficial and deep venous systems as well as knowledge of communicanting veins between superficial veins is important for diagnosis and proper treatment of chronic venous disorder. Variabilities of these veins can play fundamental role in choosing the proper graft for aorto-coronary bypass grafting. The ununiformed nomenclature of superficial veins, their communicating veins and junctions can cause misleading preoperative diagnosis and overlooking of these structures in clinical practise.

Eligibility criteria: Inclusion Criteria:

* women and men
* age 18-80

Exclusion Criteria:

* wounds on lower limbs

Primary outcomes:
measure: The Anatomy of superficial Veins of Lower Limbs
timeFrame: 2022-2024
Secondary outcomes:
measure: The Anatomy of Superficial Veins of Lower Limbs: junction saphenopopliteal
timeFrame: 2022-2024
Other outcomes:
Locations:
city: Prague
country: Czechia
facility: First faculty of medicine, Charles University
Study officials:
affiliation: 1. faculty of Medicine, Charles University
name: Michaela Hronová, doctor
role: PRINCIPAL_INVESTIGATOR
References: