Clinical trial NCT06906783: Transtibial Pull Out Method Versus Suture Anchor Method for Meniscus Extrusion
Official title: Comparison of Transtibial Pull Out Method And Suture Anchor Method in Surgical Treatment of Meniscus Extrusion
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Meniscal Extrusion
Meniscus Injury
Keywords: Meniscus Extrusion
Surgical Treatment
Transtibial Pull Out
Suture Anchor Method
Lead sponsor: Ataturk University
Sponsor class: OTHER
First posted: 2025-04-02
Enrollment: 46
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The concept of meniscal extrusion has recently been recognized as an important pathological condition associated with meniscal dysfunction. Meniscal extrusion is the medial or lateral displacement of the meniscus beyond the edges of the tibial plateau. Some meniscal extrusions are physiologic, but large degrees of extrusion are thought to be pathologic.

Meniscal extrusion can vary in extent from minimal physiological extrusion to extrusions exceeding 10 mm. The generally accepted threshold value is considered to be 3 mm.

To date, the gold standard for measuring meniscal extrusion is T2-weighted MRI. MRI is valuable not only due to its ability to define other meniscal or knee pathologies but also because it provides good sensitivity and specificity.

Surgical treatment of meniscal extrusion is preferred in young, active, symptomatic patients and individuals with acute injuries. The treatment approach may vary depending on the underlying cause. One of these methods is centralization surgery, which aims to achieve the anatomical reduction of the extruded meniscus.

The aim of this study is to compare the functional outcomes of transtibial pull-out and suture anchor techniques used in centralization surgery and to contribute to standardization.


Eligibility criteria: Inclusion Criteria:

* Presence of meniscal extrusion greater than 3 mm on MRI scans
* Symptomatic complaints in the knee with extrusion

Exclusion Criteria:

* Malalignment greater than 5 degrees
* Presence of Kellgren-Lawrence grade 3-4 osteoarthritis

Primary outcomes:
measure: Change in the amount of meniscus extrusion in MR images.
timeFrame: From enrollment to the end of treatment at 12 months
Secondary outcomes:
measure: Lysholm score
timeFrame: From enrollment to the end of treatment at 3, 6 and 12 months.
measure: Tegner activity score
timeFrame: From enrollment to the end of treatment at 3, 6 and 12 months.
measure: International Knee Documentation Committee (IKDC) Score
timeFrame: From enrollment to the end of treatment at 3, 6 and 12 months.
Other outcomes:
Locations:
city: Erzurum
country: Turkey
facility: Ataturk University Hospital
state: Yakutiye
Study officials:
affiliation: Ataturk University
name: Ahmet E Paksoy, Assoc.Prof.
role: STUDY_DIRECTOR
References:
citation: Yan X, Sahu S, Li H, Zhou W, Xiong T, Chen S, Li C, Hao L. Arthroscopic meniscal posterior root repair combined with centralization reduces medial menicus extrusion associated with posterior root tears: One-year clinical outcomes. Knee Surg Sports Traumatol Arthrosc. 2024 Nov 14. doi: 10.1002/ksa.12533. Online ahead of print.
citation: Zhou Y, Yang Q, Kang J, Xu J, Chen M, Wu C. Clinical effect of medial meniscus posterior root repair combined with centralization technique in the treatment of medial meniscus posterior root tears. BMC Musculoskelet Disord. 2024 Nov 30;25(1):982. doi: 10.1186/s12891-024-08125-2.