Clinical trial NCT02596893: Efficacy and Safety Study of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease
Official title: A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Investigate the Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: PHASE3
Conditions: Crohn Disease
Keywords: Crohn's Disease
GED-0301
Mongersen
IBD
Safety
Efficacy
Lead sponsor: Celgene
Sponsor class: INDUSTRY
First posted: 2015-11-04
Enrollment: 701
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of study is to test the effects of an experimental medication GED-0301 (mongersen) in patients who have active Crohn's disease. The study will test GED-0301 compared to placebo for 52 weeks. The study treatment is blinded which means that patients and the study doctor will not know which treatment has been assigned. Patients in this study will be allowed treatment with stable doses of oral aminosalicylates, oral corticosteroids, immunosupressants and antibiotics for the treatment of Crohn's disease.

After 12 weeks in the study until the end of the study, patients who do not have an improvement in their Crohns disease symptoms will have the option to enter a long term active treatment study. Participants who discontinued the study anytime or completed the study at Week 52 were then observed for an additional 4 weeks.


Eligibility criteria: Inclusion Criteria:

Subjects must satisfy the following criteria to be enrolled in the study:

* Male or female ≥ 18 years
* Active Crohn's disease (CD) disease as determined by the Crohn's Disease Activity Index (CDAI) score and the Simple Endoscopic Score for Crohn's Disease (SES-CD)
* Must meet a determined average minimum number of daily stools or rating of abdominal pain over a 7 day period
* Subject must have failed or experienced intolerance to at least one of the following: budesonide; systemic corticosteroids; immunosuppressants (eg, azathiopurine, 6-mercaptopurine, or methotrexate); or biologics for the treatment of CD.

Exclusion Criteria:

The presence of any of the following will exclude a subject from enrollment:

* Diagnosis of ulcerative colitis (UC), indeterminate colitis, ischemic colitis, microscopic colitis, radiation colitis or diverticular disease-associated colitis
* Local manifestations of Crohn's Disease (CD) such as symptomatic/severe strictures, abscesses, short bowel syndrome; or other disease complications for which surgery might be indicated or could confound the evaluation of efficacy
* Intestinal resection within 6 months or any intra-abdominal surgery within 3 months prior to the Screening Visit
* Ileostomy or a colostomy
* Subject has a history of any clinically significant medical condition that, in the investigator's opinion, would prevent the subject from participating in the study.

Primary outcomes:
measure: The Percentage of Participants Who Achieved a Clinical Remission at Week 12
timeFrame: Week 12
Secondary outcomes:
measure: Percentage of Participants Who Achieved Clinical Remission at Week 52
timeFrame: Week 52
measure: Percentage of Participants With Endoscopic Response-50 Centrally Read at Week 52
timeFrame: Week 52
measure: The Percentage of Participants Who Achieved a Clinical Response at Week 12
timeFrame: Week 12
measure: The Percentage of Participants Who Achieved a Clinical Response at Week 4
timeFrame: Week 4
measure: The Percentage of Participants Who Achieved a Clinical Remission at Week 4
timeFrame: Week 4
measure: The Percentage of Participants Who Achieved a Corticosteroid-Free Clinical Remission at Week 52
timeFrame: Week 52
measure: Percentage of Participants Who Achieved a Sustained Clinical Remission at Both Week 12 and 52
timeFrame: Weeks 12 and 52
measure: Percentage of Participants With Endoscopic Response-25 Centrally Read at Week 12
timeFrame: Week 0, Week 12
measure: Percentage of Participants With Endoscopic Remission Centrally Read at Week 52
timeFrame: Week 52
measure: The Number of Participants Who Experienced Treatment Emergent Adverse Events (TEAE) From Week 0 to Week 52
timeFrame: From the first day of GED-0301 until 28 days after the last dose of investigational product (IP); maximum treatment duration was 52.6 weeks
measure: The Number of Participants Who Discontinued IP Due to an Treatment Emergent Adverse Events
timeFrame: From the first day of GED-0301 until 28 days after the last dose of IP; maximum treatment duration was 52.6 weeks
Other outcomes:
Locations:
city: Huntsville
country: United States
facility: ADDC Research LLC
state: Alabama
city: Mesa
country: United States
facility: Arizona Digestive Health
state: Arizona
city: Phoenix
country: United States
facility: Mayo Clinic Arizona
state: Arizona
city: Scottsdale
country: United States
facility: Colon & Digestive Health Specialists
state: Arizona
city: Sun City
country: United States
facility: Arizona Digestive Health
state: Arizona
city: Little Rock
country: United States
facility: Gastroenterology Associates PA
state: Arkansas
city: Anaheim
country: United States
facility: HCP Clinical Research LLC
state: California
city: Encino
country: United States
facility: T. Joseph Raoof MD Inc
state: California
city: Garden Grove
country: United States
facility: Valley View Internal Medicine
state: California
city: Lancaster
country: United States
facility: OM Research
state: California
city: Los Angeles
country: United States
facility: University of Southern California Medical Center
state: California
city: Los Angeles
country: United States
facility: Cedars-Sinai Medical Center
state: California
city: Mission Hills
country: United States
facility: Facey Medical Foundation
state: California
city: San Diego
country: United States
facility: Medical Associates Research Group Inc.
state: California
city: San Diego
country: United States
facility: Clinical Applications Laboratories Inc
state: California
city: San Francisco
country: United States
facility: University of California at San Francisco
state: California
city: Ventura
country: United States
facility: Ventura Clinical Trials
state: California
city: Aurora
country: United States
facility: University Of Colorado
state: Colorado
city: Lafayette
country: United States
facility: Innovative Clinical Research
state: Colorado
city: Bristol
country: United States
facility: Connecticut Gastroenterology Institute
state: Connecticut
city: Hamden
country: United States
facility: Medical Research Center of Connecticut LLC
state: Connecticut
city: Hartford
country: United States
facility: Connecticut GI PC Research Division
state: Connecticut
city: New Haven
country: United States
facility: Yale University
state: Connecticut
city: Gainesville
country: United States
facility: Florida Medical Research - Southeastern Integrated Medical
state: Florida
city: Gainesville
country: United States
facility: Sarkis Clinical Trials - Parent
state: Florida
city: Jacksonville
country: United States
facility: Borland-Groover Clinic
state: Florida
city: Largo
country: United States
facility: Florida Center for Gastroenterology
state: Florida
city: Miami Springs
country: United States
facility: Galiz Research LLC
state: Florida
city: Miami
country: United States
facility: Advance Medical Research Center
state: Florida
city: Miami
country: United States
facility: Cordova Research Institute
state: Florida
city: Miami
country: United States
facility: My Community Research Center inc
state: Florida
city: Miami
country: United States
facility: Sanitas Research
state: Florida
city: Naples
country: United States
facility: Gastroenterology Group of Naples
state: Florida
city: Orlando
country: United States
facility: GCRM
state: Florida
city: Orlando
country: United States
facility: Center For Digestive Health
state: Florida
city: Plantation
country: United States
facility: BRCR Medical Center Inc.
state: Florida
city: Port Orange
country: United States
facility: Advanced Medical Research Center
state: Florida
city: Saint Augustine
country: United States
facility: East Coast Institute for Research LLC
state: Florida
city: Weston
country: United States
facility: Cleveland Clinic Florida Weston
state: Florida
city: Winter Park
country: United States
facility: Shafran Gastroenterology Center
state: Florida
city: Atlanta
country: United States
facility: Atlanta Gastroenterology Associates, LLC
state: Georgia
city: Augusta
country: United States
facility: Georgia Regents University
state: Georgia
city: Columbus
country: United States
facility: Columbus Regional Research Institute
state: Georgia
city: Suwanee
country: United States
facility: Atlanta Gastroenterology Specialists PC
state: Georgia
city: Idaho Falls
country: United States
facility: Grand Teton Research Group PLLC
state: Idaho
city: Chicago
country: United States
facility: Northwestern University-Feinberg School of Medicine
state: Illinois
city: Chicago
country: United States
facility: University of Chicago Medical Center
state: Illinois
city: Highland Park
country: United States
facility: NorthShore University HealthSystem
state: Illinois
city: Indianapolis
country: United States
facility: Indiana University
state: Indiana
city: Clive
country: United States
facility: Iowa Digestive Disease Center
state: Iowa
city: Pratt
country: United States
facility: Health Science Research Center, LLC
state: Kansas
city: Wichita
country: United States
facility: Heartland Research Associates LLC
state: Kansas
city: Wichita
country: United States
facility: Via Christi Research a division of Via Christi Hospitals Wichita Inc
state: Kansas
city: Bowling Green
country: United States
facility: Graves Gilbert Clinic
state: Kentucky
city: Lexington
country: United States
facility: University of Kentucky Medical Center
state: Kentucky
city: Louisville
country: United States
facility: University of Louisville
state: Kentucky
city: Baton Rouge
country: United States
facility: Gastroenterology Associates LLC
state: Louisiana
city: Lake Charles
country: United States
facility: Clinical Trials of SW Louisiana LLC
state: Louisiana
city: Shreveport
country: United States
facility: Louisiana Research Center LLC
state: Louisiana
city: Baltimore
country: United States
facility: University of Maryland Medical Center
state: Maryland
city: Baltimore
country: United States
facility: Johns Hopkins University School of Medicine
state: Maryland
city: Chevy Chase
country: United States
facility: Metropolitan Gastroenterology
state: Maryland
city: Columbia
country: United States
facility: Gastro Center of Maryland
state: Maryland
city: Boston
country: United States
facility: Boston Medical Center
state: Massachusetts
city: Brockton
country: United States
facility: Commonwealth Clinical Studies PLLC
state: Massachusetts
city: Worcester
country: United States
facility: UMass Medical Center
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan Health System
state: Michigan
city: Caro
country: United States
facility: Medex Research Institute
state: Michigan
city: Chesterfield
country: United States
facility: Clinical Research Institute of Michigan, LLC
state: Michigan
city: Novi
country: United States
facility: Henry Ford Medical Center - New Center One
state: Michigan
city: Wyoming
country: United States
facility: Gastroenterology Associates of Western Michigan PLC
state: Michigan
city: Minneapolis
country: United States
facility: University of Minnesota
state: Minnesota
city: Rochester
country: United States
facility: Mayo Clinic
state: Minnesota
city: Belton
country: United States
facility: Ehrhardt Clinical Research LLC
state: Missouri
city: Jefferson City
country: United States
facility: Jefferson City Medical Group
state: Missouri
city: Saint Louis
country: United States
facility: Saint Louis University
state: Missouri
city: Springfield
country: United States
facility: Mercy Research
state: Missouri
city: Washington
country: United States
facility: Mercy Clinic East Communities d/b/a Mercy Health Research
state: Missouri
city: Lebanon
country: United States
facility: Dartmouth-Hitchcock Medical Center
state: New Hampshire
city: Egg Harbor Township
country: United States
facility: AGA Clinical Research Associates LLC
state: New Jersey
city: Albuquerque
country: United States
facility: Southwest Gastroenterology Associates PC
state: New Mexico
city: Flushing
country: United States
facility: Sing Chan Private Practice
state: New York
city: Great Neck
country: United States
facility: NYU Langone Nassau Gastroenterology Associates
state: New York
city: Lake Success
country: United States
facility: Montefiore Medical Center PRIME
state: New York
city: Manhasset
country: United States
facility: The Feinstein Institute for Medical Research PRIME
state: New York
city: Mineola
country: United States
facility: Winthrop University Hospital
state: New York
city: New Hyde Park
country: United States
facility: North Shore Long Island Jewish Health System
state: New York
city: New York
country: United States
facility: Concord Medical Group PRIME
state: New York
city: New York
country: United States
facility: New York University School of Medicine
state: New York
city: New York
country: United States
facility: New York - Presbyterian/Weill Cornell Medical Center
state: New York
city: New York
country: United States
facility: Icahn School of Medicine at Mount Sinai
state: New York
city: New York
country: United States
facility: Columbia University Medical Center
state: New York
city: Poughkeepsie
country: United States
facility: Premier Medical Group of the Hudson Valley PC
state: New York
city: Rochester
country: United States
facility: University of Rochester
state: New York
city: Asheville
country: United States
facility: Asheville Gastroenterology Associates, PA
state: North Carolina
city: Chapel Hill
country: United States
facility: University of North Carolina at Chapel Hill
state: North Carolina
city: Charlotte
country: United States
facility: Carolina Center for Liver Disease
state: North Carolina
city: Charlotte
country: United States
facility: Gaffney Health Services
state: North Carolina
city: Charlotte
country: United States
facility: Carolinas Medical Center
state: North Carolina
city: Greensboro
country: United States
facility: PhysiqueMed Clinical Trials
state: North Carolina
city: Kinston
country: United States
facility: Kinston Medical Specialists PA
state: North Carolina
city: Mount Airy
country: United States
facility: Clinical Trials of America, LLC
state: North Carolina
city: Wilmington
country: United States
facility: Trial Management Associates LLC
state: North Carolina
city: Winston-Salem
country: United States
facility: PMG Research of Winston-Salem LLC
state: North Carolina
city: Winston-Salem
country: United States
facility: Wake Forest University Baptist Medical Center
state: North Carolina
city: Akron
country: United States
facility: Ohio Clinical Research Partners LLC
state: Ohio
city: Centerville
country: United States
facility: Dr. Deepak Sarwal, MD
state: Ohio
city: Cincinnati
country: United States
facility: UC Health Clinical Trials Office
state: Ohio
city: Cincinnati
country: United States
facility: Consultants for Clinical Research Inc.
state: Ohio
city: Cleveland
country: United States
facility: Cleveland Clinic Foundation
state: Ohio
city: Cleveland
country: United States
facility: University Hospitals Case Medical Center
state: Ohio
city: Huber Heights
country: United States
facility: Clinical Inquest Center Ltd
state: Ohio
city: Springfield
country: United States
facility: Springfield Health Care Center
state: Ohio
city: Oklahoma City
country: United States
facility: Oklahoma University Health Sciences Center
state: Oklahoma
city: Portland
country: United States
facility: Oregon Health and Science University
state: Oregon
city: Havertown
country: United States
facility: Main Line Gastroenterology
state: Pennsylvania
city: Philadelphia
country: United States
facility: Drexel University College of Medicine
state: Pennsylvania
city: Philadelphia
country: United States
facility: University of Pennsylvania School of Medicine
state: Pennsylvania
city: State College
country: United States
facility: Penn State University Milton S Hershey Medical Center
state: Pennsylvania
city: Chattanooga
country: United States
facility: ClinSearch LLC
state: Tennessee
city: Germantown
country: United States
facility: Gastro One
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt University Medical Center
state: Tennessee
city: Arlington
country: United States
facility: Texas Clinical Research Institute LLC
state: Texas
city: Arlington
country: United States
facility: Texas Digestive Disease Consultants - Dallas
state: Texas
city: Dallas
country: United States
facility: Texas Digestive Disease Consultants Dallas
state: Texas
city: Flower Mound
country: United States
facility: Texas Digestive Disease Consultants - Southlake
state: Texas
city: Houston
country: United States
facility: Gulf Coast Research Group LLC
state: Texas
city: Houston
country: United States
facility: The Methodist Hospital Research Institute
state: Texas
city: Houston
country: United States
facility: University of Texas Health Science Center at Houston
state: Texas
city: Houston
country: United States
facility: Houston Endoscopy and Research Center
state: Texas
city: San Antonio
country: United States
facility: Sagact Pllc
state: Texas
city: San Antonio
country: United States
facility: San Antonio Military Medical Center
state: Texas
city: Temple
country: United States
facility: Scott & White Medical Center
state: Texas
city: Tyler
country: United States
facility: Digestive Health Specialist of Tyler
state: Texas
city: Salt Lake City
country: United States
facility: University of Utah
state: Utah
city: Colchester
country: United States
facility: University of Vermont
state: Vermont
city: Charlottesville
country: United States
facility: University of Virginia
state: Virginia
city: Charlottesville
country: United States
facility: Charlottesville Medical Research Center
state: Virginia
city: Chesapeake
country: United States
facility: Gastroenterology Associates of Tidewater
state: Virginia
city: Leesburg
country: United States
facility: Emeritas Research Group
state: Virginia
city: Norfolk
country: United States
facility: Digestive and Liver Disease Specialists
state: Virginia
city: Richmond
country: United States
facility: Hunter Holmes Mcguire Ctr
state: Virginia
city: Seattle
country: United States
facility: Virginia Mason Medical Center
state: Washington
city: Seattle
country: United States
facility: Harborview Medical Center
state: Washington
city: Seattle
country: United States
facility: Swedish Medical Center
state: Washington
city: Seattle
country: United States
facility: University of Washington School of Medicine
state: Washington
city: Vancouver
country: United States
facility: The Vancouver Clinic
state: Washington
city: Madison
country: United States
facility: Dean Clinic Oregon
state: Wisconsin
city: Madison
country: United States
facility: University of Wisconsin Hospital and Clinics
state: Wisconsin
city: Milwaukee
country: United States
facility: Medical College of Wisconsin
state: Wisconsin
city: Bankstown
country: Australia
facility: Bankstown-Lidcombe Hospital
state: Australian Capital Territory
city: Camperdown
country: Australia
facility: Royal Prince Alfred Hospital
state: New South Wales
city: Concord
country: Australia
facility: Concord Repatriation General Hospital
state: New South Wales
city: Five Dock
country: Australia
facility: Centre For Digestive Diseases
state: New South Wales
city: Liverpool
country: Australia
facility: Liverpool Hospital
state: New South Wales
city: South Brisbane
country: Australia
facility: Mater Adult Hospital
state: Queensland
city: Woolloongabba
country: Australia
facility: Princess Alexandra Hospital
state: Queensland
city: Adelaide
country: Australia
facility: Royal Adelaide Hospital
state: South Australia
city: Bedford Park
country: Australia
facility: Flinders Medical Centre
state: South Australia
city: Box Hill
country: Australia
facility: Box Hill Hospital
state: Victoria
city: Melbourne
country: Australia
facility: The Alfred Hospital
state: Victoria
city: Murdoch
country: Australia
facility: Fiona Stanley Hospital
state: Western Australia
city: Ballarat
country: Australia
facility: Ballarat Base Hospital
city: Bentleigh East
country: Australia
facility: Monash Medical Centre Clayton
city: Fitzroy
country: Australia
facility: St Vincents Hospital Melbourne
city: Heidelberg
country: Australia
facility: Austin Hospital
city: Herston
country: Australia
facility: Royal Brisbane and Women's Hospital
city: Kingswood, NSW
country: Australia
facility: Nepean Hospital
city: Graz
country: Austria
facility: LKH Universitaetsklinikum Graz
city: Innsbruck
country: Austria
facility: Medizinische Universitat Innsbruck
city: Klagenfurt
country: Austria
facility: Klinikum Klagenfurt am Wörtersee
city: Linz
country: Austria
facility: KH der Barmherzigen Bruder Linz
city: Ried I Innkreis
country: Austria
facility: a.o.Krankenhaus d.Barmherz.Schwestern Ried
city: Salzburg
country: Austria
facility: LKH - Universitätsklinikum der PMU Salzburg
city: Salzburg
country: Austria
facility: Ordination Dr. Thomas Haas Darmpraxis Salzburg
city: St Veit An Der Glan
country: Austria
facility: KH der Barmherzigen Brüder St.Veit an der Glan
city: Wein
country: Austria
facility: Krankenanstalt Rudolfstiftung Wien
city: Wein
country: Austria
facility: AKH Medizinische Universitat Wien
city: Brussels
country: Belgium
facility: Universitair Ziekenhuis Brussel
city: Bruxelles
country: Belgium
facility: Cliniques Universitaires St Luc
city: Gent
country: Belgium
facility: Universitair Ziekenhuis Gent
city: Leuven
country: Belgium
facility: UZ Leuven
city: Liege
country: Belgium
facility: CHU Sart Tilman
city: Mouscron
country: Belgium
facility: Centre Hospitalier de Mouscron
city: Lom
country: Bulgaria
facility: MHAT Sv Nikolay Chudotvorets EOOD
city: Plovdiv
country: Bulgaria
facility: MHAT Kaspela EOOD
city: Ruse
country: Bulgaria
facility: MHAT Ruse AD
city: Sofia
country: Bulgaria
facility: Second MHAT Sofia AD
city: Sofia
country: Bulgaria
facility: City Clinic UMHAC EOOD
city: Sofia
country: Bulgaria
facility: UMHAT Sv Ivan Rilski EAD
city: Sofia
country: Bulgaria
facility: UMHAT Tsaritsa Yoanna - ISUL EAD
city: Sofia
country: Bulgaria
facility: Fourth MHAT Sofia EAD
city: Sofia
country: Bulgaria
facility: MHAT Doverie AD
city: Calgary
country: Canada
facility: University of Calgary
state: Alberta
city: Edmonton
country: Canada
facility: GI Research Institute
state: Alberta
city: Edmonton
country: Canada
facility: University of Alberta
state: Alberta
city: Edmonton
country: Canada
facility: South Edmonton Gastroenterology
state: Alberta
city: Vancouver
country: Canada
facility: Vancouver General Hospital
state: British Columbia
city: Vancouver
country: Canada
facility: GI Research Institute
state: British Columbia
city: Victoria
country: Canada
facility: PerCuro Clinical Research
state: British Columbia
city: Brandon
country: Canada
facility: Brandon Medical Arts Clinic
state: Manitoba
city: Barrie
country: Canada
facility: Barrie GI Associates
state: Ontario
city: Hamilton
country: Canada
facility: McMaster University Health Sciences Center
state: Ontario
city: London
country: Canada
facility: London Health Science Center U. Hospital
state: Ontario
city: London
country: Canada
facility: LHSC Victoria Hospital
state: Ontario
city: Ottawa
country: Canada
facility: Montfort Hospital
state: Ontario
city: Toronto
country: Canada
facility: Humber River Hospital
state: Ontario
city: Toronto
country: Canada
facility: Mount Sinai Hospital
state: Ontario
city: Toronto
country: Canada
facility: Toronto Liver Centre
state: Ontario
city: Vaughan
country: Canada
facility: Toronto Digestive Disease Associates Inc
state: Ontario
city: Waterloo
country: Canada
facility: Medicine Professional Corporation
state: Ontario
city: Windsor
country: Canada
facility: Tarabain Osman MD
state: Ontario
city: Greenfield Park
country: Canada
facility: Centre de sante et de services sociaux Champlain Charles Le Moyne
state: Quebec
city: Montreal
country: Canada
facility: Recherche GCP Research
state: Quebec
city: Montreal
country: Canada
facility: Hopital Maisonneuve Rosemont dba CIUSSS de lEst de lIle de Montreal
state: Quebec
city: Montreal
country: Canada
facility: CHUM Hôpital Saint-Luc
state: Quebec
city: Montreal
country: Canada
facility: McGill University Health Centre Glen Site Royal Victoria Hospital
state: Quebec
city: Sherbrooke
country: Canada
facility: CHUS Hopital Fleurimont
state: Quebec
city: St Jerome
country: Canada
facility: Recherche Medicale St Jerome Inc
state: Quebec
city: Saskatoon
country: Canada
facility: Royal University Hospital
state: Saskatchewan
city: Quebec
country: Canada
facility: Recherche Clinique Sigma Inc
city: Osijek
country: Croatia
facility: Clinical Hospital Centre Osijek
city: Rijeka
country: Croatia
facility: Clinical Hospital Centre Rijeka
city: Zagreb
country: Croatia
facility: Clinical Hospital Centre Zagreb
city: Zagreb
country: Croatia
facility: Clinical Hospital Dubrava
city: Zagreb
country: Croatia
facility: Clinical Hospital Merkur
city: Zagreb
country: Croatia
facility: Clinical Hospital Sveti Duh
city: Brno
country: Czechia
facility: Fakultni nemocnice u sv Anny v Brne
city: Hradec Kralove
country: Czechia
facility: Hepato-Gastroenterologie HK
city: Most
country: Czechia
facility: Soukroma Gastroenterologicka ambulance a endoskopie
city: Olomouc
country: Czechia
facility: PreventaMed
city: Pardubice
country: Czechia
facility: CCBR Czech as
city: Praha 3
country: Czechia
facility: CCBR Prague CZ
city: Praha 7
country: Czechia
facility: IBD Centrum ISCARE IVF as
city: Usti nad Labem
country: Czechia
facility: Krajska zdravotni, a.s. - Masarykova nemocnice v Usti nad La
city: Znojmo
country: Czechia
facility: Nemocnice Znojmo
city: Aahus C
country: Denmark
facility: Aarhus Universitetshospital
city: Frederikssund
country: Denmark
facility: Nordsjaellands Hospital Frederikssund
city: Herlev
country: Denmark
facility: Herlev Hospital
city: Hvidovre
country: Denmark
facility: Hvidovre Hospital
city: Koge
country: Denmark
facility: Koge Sygehus
city: Silkeborg
country: Denmark
facility: Regionshospitalet Silkeborg
city: Ålborg
country: Denmark
facility: Alborg University Hospital
city: Tallinn
country: Estonia
facility: West Tallinn Central Hospital
city: Tartu
country: Estonia
facility: Tartu University Hospital
city: Tampere
country: Finland
facility: Tampereen yliopistollinen sairaala
city: Turku
country: Finland
facility: Turunmaan sairaala
city: Amiens Cedex
country: France
facility: CHU Amiens Hopital Sud
city: Besancon Cedex
country: France
facility: CHU Besancon Hopital Jean Minjoz
city: Chambray les Tours
country: France
facility: CHU Tours Hopital Trousseau
city: Clermont-Ferrand
country: France
facility: CHU Clermont Ferrand
city: Clichy cedex
country: France
facility: Hopital Beaujon
city: Dijon
country: France
facility: CHU Dijon - Hopital Bocage Central
city: Grenoble cedex 9
country: France
facility: CHU de Grenoble Hopital Nord
city: Le Kremlin Bicetre cedex
country: France
facility: Groupement Hospitalier Sud Hopital Bicetre
city: Lille cedex
country: France
facility: Hopital Claude Huriez CHRU Lille
city: Marseille cedex 20
country: France
facility: Hopital Nord
city: Nantes Cedex 1
country: France
facility: CHU Nantes Hotel Dieu
city: Nice Cedex 3
country: France
facility: CHU Nice Hopital de lArchet 2
city: Paris
country: France
facility: Hopital Saint Antoine
city: Paris
country: France
facility: Hopital Saint Louis
city: Pessac
country: France
facility: Groupe Hospitalier Sud Hopital Haut Leveque USN
city: Pierre-Bénite Cedex
country: France
facility: Centre Hospitalier Lyon Sud
city: Reims
country: France
facility: CHU Reims Hopital Robert Debre
city: Rennes cedex 09
country: France
facility: CHU Rennes Hopital Pontchaillou
city: Rouen Cedex
country: France
facility: CHU de Rouen Hopital Charles Nicolle
city: Saint Etienne
country: France
facility: CHU Saint Etienne Hopital Nord
city: Strasbourg Cedex
country: France
facility: CHU Strasbourg Hopital Hautepierre
city: Toulouse Cedex 09
country: France
facility: CHU de Toulouse Hopital Rangueil
city: Vandoeuvre les Nancy
country: France
facility: Hopital de Brabois Adultes
city: Berlin
country: Germany
facility: Charite Universitaetsmedizin Berlin Campus Benjamin Franklin
city: Berlin
country: Germany
facility: Charite Campus Virchow Klinikum
city: Berlin
country: Germany
facility: DRK Kliniken Berlin Westend
city: Berlin
country: Germany
facility: Krankenhaus Waldfriede e V
city: Bochum
country: Germany
facility: Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil GmbH
city: Brandenburg an der Havel
country: Germany
facility: Staedisches Klinikum Brandenburg
city: Dresden
country: Germany
facility: Universitaetsklinikum Carl Gustav Carus TU Dresden
city: Duesseldorf
country: Germany
facility: Zentrum fuer HIV und Hepatogastroenterologie GmbH
city: Erlangen
country: Germany
facility: Universitaetsklinikum Erlangen
city: Essen
country: Germany
facility: Kliniken Essen-Mitte
city: Essen
country: Germany
facility: Katholische Kliniken Ruhrhalbinsel GmbH
city: Frankfurt
country: Germany
facility: Agaplesion Markus Krankenhaus
city: Frankfurt
country: Germany
facility: Crohn Colitis Centrum Rhein Main
city: Freiburg
country: Germany
facility: Universitaetsklinikum FreiburgInnere Med.1, Haematologie
city: Halle
country: Germany
facility: Universitaetsklinikum Halle Saale
city: Hamburg
country: Germany
facility: Asklepios Klinik Hamburg
city: Hannover
country: Germany
facility: Medizinische Hochschule Hannover
city: Heidelberg
country: Germany
facility: Universitatsklinikum Heidelberg
city: Heidelberg
country: Germany
facility: Praxis fuer Gastroenterologie Dr Ehehal Dr Helmstaedter
city: Jena
country: Germany
facility: Universitaetsklinikum Jena
city: Kiel
country: Germany
facility: Universitaetsklinikum Schleswig Holstein Campus Kiel
city: Leipzig
country: Germany
facility: University Leipzig
city: Leipzig
country: Germany
facility: Internistische Gemeinschaftspraxis f. Verdauungs- und Stoffwechselerkrankungen
city: Leipzig
country: Germany
facility: EUGASTRO GmbH
city: Lueneburg
country: Germany
facility: Medizinisches Zentrum Klinikum Lueneburg
city: Magdeburg
country: Germany
facility: Universitaetsklinikum Magdeburg A oeR
city: Mannheim
country: Germany
facility: Klinikum Mannheim GmbH Universitaetsklinikum
city: Minden
country: Germany
facility: Gastroenterologische Praxis Minden
city: Muenchen
country: Germany
facility: Isar Klinik GmbH
city: Muenster
country: Germany
facility: Universitaetsklinikum Muenster
city: Muenster
country: Germany
facility: Gastro Campus Research
city: München
country: Germany
facility: Klinikum der Universitaet Muenchen
city: Niedersachsen
country: Germany
facility: Staedtisches Klinikum Braunschweig gGmbH Standort Salzdahlumer
city: Regensburg
country: Germany
facility: Universitaetsklinikum Regensburg
city: Ulm
country: Germany
facility: Universitaetsklinikum Ulm
city: Alexandroupolis
country: Greece
facility: University General Hospital of Alexandroupolis
city: Athens
country: Greece
facility: General Hospital of Athens Evangelismos
city: Athens
country: Greece
facility: Athens Medical Center
city: Athens
country: Greece
facility: General Hospital of Nikaea Piraeus Ag. Panteleimon
city: Heraklion
country: Greece
facility: University General Hospital of Heraklion
city: Heraklion
country: Greece
facility: General Hospital of Heraklion Benizeleio Pananeio
city: Ioannina
country: Greece
facility: University General Hospital of Ioannina
city: Rio Patras
country: Greece
facility: University General Hospital of Patras
city: Thessaloniki
country: Greece
facility: Anticancer Hospital of Thessaloniki THEAGENIO
city: Thessaloniki
country: Greece
facility: General Hospital of Thessaloniki Hippokration
city: Balatonfured
country: Hungary
facility: DRC Gyogyszervizsgalo Kozpont Kft
city: Budapest
country: Hungary
facility: Clinexpert Egeszsegugyi Szolg es Ker Kft
city: Budapest
country: Hungary
facility: Magyar Honvedseg Egeszsegugyi Kozpont
city: Budapest
country: Hungary
facility: Semmelweis Egyetem AOK
city: Budapest
country: Hungary
facility: Semmelweis Egyetem AOK
city: Budapest
country: Hungary
facility: Szent Janos Korhaz es Eszak-budai Egyesitett Korhazak
city: Budapest
country: Hungary
facility: Pannonia Maganorvosi Centrum
city: Budapest
country: Hungary
facility: Endomedix Diagnosztikai Kozpont
city: Debrecen
country: Hungary
facility: Debreceni Egyetem Klinikai Kozpont
city: Dunaujvaros
country: Hungary
facility: Szent Pantaleon Korhaz Rendelointezet Dunaujvaros
city: Eger
country: Hungary
facility: Markhot Ferenc Oktato Korhaz es Rendelointezet
city: Gyor
country: Hungary
facility: Petz Aladar Megyei Oktato Korhaz
city: Gyula
country: Hungary
facility: Bekes Megyei Pandy Kalman Korhaz
city: Kaposvar
country: Hungary
facility: Somogy Megyei Kaposi Mor Oktato Korhaz
city: Mohacs
country: Hungary
facility: Mohacsi Korhaz
city: Nyiregyhaza
country: Hungary
facility: SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz
city: Szeged
country: Hungary
facility: Mazso-Pharma Kutatas-fejlesztesi Kft
city: Szekesfehervar
country: Hungary
facility: Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz
city: Szekszard
country: Hungary
facility: Clinfan Szolgaltato Kft
city: Afula
country: Israel
facility: HaEmek Medical Center
city: Beer Sheva
country: Israel
facility: Soroka University Medical Center
city: Haifa
country: Israel
facility: Rambam Health Care Campus
city: Holon
country: Israel
facility: Wolfson Medical Center
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center
city: Jerusalem
country: Israel
facility: Hadassah University Hospital
city: Petah Tikva
country: Israel
facility: Rabin Medical Center
city: Ramat Gan
country: Israel
facility: Chaim Sheba Medical Center
city: Rechovot
country: Israel
facility: Kaplan Medical Center
city: Tel Aviv
country: Israel
facility: Tel Aviv Sourasky Medical Center Department of Hematology
city: Zerifin
country: Israel
facility: Assaf Harofeh Medical Center
city: Bari
country: Italy
facility: Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
city: Bologna
country: Italy
facility: Azienda Ospedaliera Universitaria Policlinico Sant Orsola Malpighi
city: Messina
country: Italy
facility: Azienda Ospedaliera Universitaria Policlinico G Martino
city: Milano
country: Italy
facility: Fondazione IRCCS CA Granda Ospedale Maggiore Policlinico
city: Naples
country: Italy
facility: Seconda Universita Degli Studi Di Napoli
city: Napoli, Campania
country: Italy
facility: Azienda Ospedaliera Universitaria Federico II
city: Padova
country: Italy
facility: Hospital of Di Padova
city: Palermo
country: Italy
facility: Azienda Ospedaliera Vincenzo Cervello
city: Pavia
country: Italy
facility: Fondazione IRCCS Policlinico San Matteo
city: Pisa
country: Italy
facility: Azienda Ospedaliero Universitaria Pisana
city: Roma
country: Italy
facility: Universita Campus Bio-Medico di Roma
city: Roma
country: Italy
facility: Ospedale Sandro Pertini
city: Roma
country: Italy
facility: Complesso Integrato Columbus
city: Roma
country: Italy
facility: Policlinico Universitario Agostino Gemelli
city: Rome
country: Italy
facility: Azienda Ospedaliera San Camillo Forlanini
city: Rome
country: Italy
facility: Azienda Ospedaliera Universitaria Policlinico Tor Vergata
city: Rozzano (MI)
country: Italy
facility: Istituto Clinico Humanitas
city: Salerno
country: Italy
facility: Azienda Ospedaliera Universitaria OO. RR. S. Giovanni di Dio e Ruggi dAragona
city: San Donato Milanese
country: Italy
facility: IRCCS Policlinico San Donato
city: San Giovanni Rotondo FG
country: Italy
facility: IRCCS Ospedale Casa Sollievo della Sofferenza
city: Busan
country: Korea, Republic of
facility: Dong-A University Hospital
city: Busan
country: Korea, Republic of
facility: Pusan National University Hospital
city: Daegu
country: Korea, Republic of
facility: Yeungnam University Medical Center
city: Guri-si
country: Korea, Republic of
facility: Hanyang Univerisy Guri Hospital
city: Seongnam-si,
country: Korea, Republic of
facility: CHA Bundang Medical Center CHA University
city: Seongnam-si
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
city: Seoul
country: Korea, Republic of
facility: Kyung Hee University Hospital
city: Seoul
country: Korea, Republic of
facility: Kangbuk Samsung Hospital
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center
city: Seoul
country: Korea, Republic of
facility: Severance Hospital, Yonsei University Health System
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center
city: Seoul
country: Korea, Republic of
facility: Korea University Anam Hospital
city: Seoul
country: Korea, Republic of
facility: Ewha Womans University Mokdong Hospital
city: Suwon-si
country: Korea, Republic of
facility: The Catholic University of Korea, St.Vicent's Hospital
city: Riga
country: Latvia
facility: Digestive Diseases Center Gastro
city: Riga
country: Latvia
facility: Riga East Clinical University Hospital clinic Gailezers
city: Riga
country: Latvia
facility: Pauls Stradins Clinical University Hospital
city: Alor Setar
country: Malaysia
facility: Hospital Sultanah Bahiyah
state: Kedah
city: Kota Bahru
country: Malaysia
facility: Hospital Raja Perempuan Zainab II
state: Kelantan
city: Ampang
country: Malaysia
facility: Hospital Ampang
state: Selangor
city: Kuala Lumpur
country: Malaysia
facility: University Malaya Medical Centre
state: Wilayah Persekutuan Kuala Lumpur
city: Kelantan
country: Malaysia
facility: Hospital Universiti Sains Malaysia
city: Amsterdam
country: Netherlands
facility: VU Medisch Centrum
city: Amsterdam
country: Netherlands
facility: Academisch Medisch Centrum
city: Breda
country: Netherlands
facility: Amphia Ziekenhuis
city: Groningen
country: Netherlands
facility: Universitair Medisch Centrum Groningen
city: Leiden
country: Netherlands
facility: Leiden Universitair Medisch Centrum
city: Leidschendam
country: Netherlands
facility: Medisch Centrum Haaglanden,Antoniushoeve
city: Nijmegen
country: Netherlands
facility: Radboudumc
city: Sittard-Geleen
country: Netherlands
facility: Zuyderland Medisch Centrum
city: Tilburg
country: Netherlands
facility: St. Elisabeth Ziekenhuis
city: Utrecht
country: Netherlands
facility: University Medical Center Utrecht
city: Hamilton
country: New Zealand
facility: Waikato Hospital
city: Fredrikstad
country: Norway
facility: Sykehuset Ostfold Fredrikstad
city: Lørenskog
country: Norway
facility: Akershus universitetssykehus HF
city: Oslo
country: Norway
facility: Oslo Universitetssykehus HF Ulleval
city: Oslo
country: Norway
facility: Oslo Universitetssykehus Rikshospitalet
city: Stavanger
country: Norway
facility: Stavanger Unviversitetssjukehus Helse Stavanger HF
city: Bialystok
country: Poland
facility: SP ZOZ Wojewodzki Szpital Zespolony im. J. Sniadeckiego
city: Bydgoszcz
country: Poland
facility: Clinsante S.C. Osrodek Badan Klinicznych
city: Gdansk
country: Poland
facility: Uniwersyteckie Centrum Kliniczne
city: Kielce
country: Poland
facility: Niepubliczny Zaklad Opieki Zdrowotnej POLIMEDICA
city: Knurow
country: Poland
facility: Indywidualna Praktyka Lekarska Maciej Zymla
city: Krakow
country: Poland
facility: Centrum Medyczne Plejady
city: Krakow
country: Poland
facility: LUX MED Sp. z o.o.
city: Krakow
country: Poland
facility: SPZOZ Szpital Uniwersytecki w Krakowie
city: Lodz
country: Poland
facility: SPZOZ Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej - Centralny Szpital Weteranow
city: Lodz
country: Poland
facility: Centrum Medyczne AMED
city: Lublin
country: Poland
facility: GASTROMED Sp.zo.o.
city: Poznan
country: Poland
facility: Ai Centrum Medyczne Sp. Z O.O. Sp.K.
city: Rzeszow
country: Poland
facility: Centrum Medyczne Medyk
city: Sopot
country: Poland
facility: Endoskopia Sp. z o.o.
city: Warsaw
country: Poland
facility: Nzoz Vivamed
city: Wroclaw
country: Poland
facility: LexMedica Osrodek Badan Klinicznych
city: Braga
country: Portugal
facility: Hospital de Braga
city: Coimbra
country: Portugal
facility: Centro Hospitalar E Universitario de Coimbra EPE
city: Guimaraes
country: Portugal
facility: Hospital da Senhora da Oliveira Guimaraes
city: Lisboa
country: Portugal
facility: Hospital Da Luz
city: Porto
country: Portugal
facility: Centro Hospitalar de Sao Joao, EPE
city: Viana do Castelo
country: Portugal
facility: Centro Hospitalar do Alto Minho - Unidade Local de Saúde do Alto Minho, EPE
city: Bucuresti
country: Romania
facility: S.C MedLife S.A
city: Cluj Napoca
country: Romania
facility: Tvm Med Serv Srl
city: Iasi
country: Romania
facility: Spitalul Clinic Judetean de Urgente Sf. Spiridon
city: Oradea
country: Romania
facility: CMI Dr. Tirnaveanu Amelita
city: Timisoara
country: Romania
facility: Centrul de Gastroenterologie Dr. Goldis
city: Irkutsk
country: Russian Federation
facility: Irkutsk State Medical Academy of Continuing Education
city: Krasnoyarsk
country: Russian Federation
facility: TSBIH Territorial Clinical Hospital
city: Moscow
country: Russian Federation
facility: Medical Center Stolitsa-Medikl
city: Nizhny Novgorod
country: Russian Federation
facility: SBHI of NN region RCH of NN n.a. N.A.Semashko
city: Novosibirsk
country: Russian Federation
facility: SBEIHPE Novosibirsk State Medical University
city: Novosibirsk
country: Russian Federation
facility: RSHI State Novosibirsk Regional Clinical Hospital
city: Novosibirsk
country: Russian Federation
facility: FSBI Scientific Research Institute of Physyology and Basic Medicine under the SB of RAMS
city: Omsk
country: Russian Federation
facility: BHI of Omsk region Clinical Oncology Dispensary
city: Omsk
country: Russian Federation
facility: SBEI of HPE Omsk State Medical Academy Ministry of healthcare of RF
city: Perm
country: Russian Federation
facility: SBIH of Perm territory City Clinical Hospital 2 na Fedor Khristoforovich Gral
city: Pushkin
country: Russian Federation
facility: Evromedservis
city: Rostov-on-Don
country: Russian Federation
facility: SEIHPE Rostov State Medical University of MoH of RF
city: Saint-Petersburg
country: Russian Federation
facility: City Mariinskaya Hospital
city: Saint-Petersburg
country: Russian Federation
facility: SPb SBIH City Hospital # 26
city: Samara
country: Russian Federation
facility: Private Educational Institution of Higher Education Medical university REAVIZ
city: Samara
country: Russian Federation
facility: NonState Healthcare Institution Central Clinical Hospital, Samara station JSC Russian Railways
city: Saratov
country: Russian Federation
facility: SHI Regional Clinical Hospital
city: Tosno
country: Russian Federation
facility: SBI of Healthcare of Leningrad region Clinical Interregional Hospital of Tosno
city: Yaroslavl
country: Russian Federation
facility: SBHI of Yaroslavl Region Clinical Hospital 8
city: Belgrade
country: Serbia
facility: Clinical Center of Serbia
city: Belgrade
country: Serbia
facility: Clinical Center Zvezdara
city: Belgrade
country: Serbia
facility: Military Medical Academy
city: Belgrade
country: Serbia
facility: Clinical Center Bezanijska Kosa
city: Belgrade
country: Serbia
facility: Clinical Center Zemun
city: Kragujevac
country: Serbia
facility: Clinical Center Kragujevac
city: Nis
country: Serbia
facility: Clinical Center Nis
city: Banska Bystrica
country: Slovakia
facility: Fakultna nemocnica s poliklinikou F. D. Roosevelta
city: Bardejov
country: Slovakia
facility: Alian s.r.o.
city: Bratislava
country: Slovakia
facility: Univerzitna nemocnica Bratislava Nemocnica Ruzinov
city: Bratislava
country: Slovakia
facility: Gastroentero-Hepatologicke centrum THALION
city: Humenne
country: Slovakia
facility: Nemocnica A.Lena Humenne n o
city: Kosice
country: Slovakia
facility: B & B MED, s.r.o.
city: Lucenec
country: Slovakia
facility: KARDIO 1 s.r.o.
city: Malacky
country: Slovakia
facility: Gastroeneterologicka ambulancia MUDr. Peter Hegyi s.r.o.
city: Nitra
country: Slovakia
facility: Fakultna nemocnica Nitra
city: Nitra
country: Slovakia
facility: KM Management, spol. s r.o.
city: Presov
country: Slovakia
facility: GASTRO I., s.r.o.
city: Roznava
country: Slovakia
facility: Nemocnica s poliklinikou sv Barbory Roznava a s
city: Zilina
country: Slovakia
facility: Fakultna nemocnica s poliklinikou Zilina
city: Badalona
country: Spain
facility: Hospital Universitari Germans Trias i Pujol
city: Barcelona
country: Spain
facility: Hospital del Mar
city: Barcelona
country: Spain
facility: Hospital Clinic I Provincial de Barcelona
city: Cordoba
country: Spain
facility: Hospital Universitario Reina Sofia
city: Madrid
country: Spain
facility: Hospital Universitario de la Princesa
city: Madrid
country: Spain
facility: Hospital Universitario Ramon y Cajal
city: Majadahonda
country: Spain
facility: Hospital Universitario Puerta de Hierro Majadahonda
city: Sabadell
country: Spain
facility: Corporacion Sanitaria Parc Tauli
city: San Sebastian de los Reyes
country: Spain
facility: Hospital Universitario Infanta Sofia
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Del Rocio
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Macarena
city: Zaragoza
country: Spain
facility: Hospital Universitario Miguel Servet
city: Stockholm
country: Sweden
facility: Sodersjukhuset
city: Stockholm
country: Sweden
facility: Danderyds Sjukhus AB
city: Uppsala
country: Sweden
facility: Akademiska Sjukhuset
city: Basel
country: Switzerland
facility: Universitaetsspital Basel
city: Bern
country: Switzerland
facility: Inselspital - Universitaetsspital Bern
city: Bern
country: Switzerland
facility: Crohn-Colitis Zentrum Bern Gemeinschaftspraxis Balsiger Seibold und Partner
city: St. Gallen
country: Switzerland
facility: Kantonsspital St.Gallen
city: Zuerich
country: Switzerland
facility: Universitaetsspital Zuerich
city: Ankara
country: Turkey
facility: Ankara University Medical Faculty
city: Ankara
country: Turkey
facility: Hacettepe University Medical Faculty
city: Ankara
country: Turkey
facility: Turkiye Yuksek Ihtisas Hospital
city: Ankara
country: Turkey
facility: Gazi University Medical Faculty
city: Elazig
country: Turkey
facility: Firat University Medical Faculty
city: Gaziantep
country: Turkey
facility: Gaziantep University Medical Faculty Sahinbey Educational Research Hospital
city: Istanbul
country: Turkey
facility: Yeditepe University Medical School Hospital
city: Istanbul
country: Turkey
facility: Istanbul University Cerrahpasa Medical Faculty Hospital
city: Istanbul
country: Turkey
facility: Acibadem Fulya Hospital
city: Istanbul
country: Turkey
facility: Haydarpasa Numune Training and Research Hospital
city: Istanbul
country: Turkey
facility: Istanbul Medeniyet Uni Goztepe Training&Res Hosp
city: Istanbul
country: Turkey
facility: Marmara University Pendik Training and Research Hospital
city: Izmir
country: Turkey
facility: Ege University Medical Faculty
city: Malatya
country: Turkey
facility: Inonu Uni. Med. Fac.
city: Mersin
country: Turkey
facility: Mersin University Medical Faculty
city: Umuttepe Kocaeli
country: Turkey
facility: Kocaeli Derince Training and Research Hospital
city: Chernivtsi
country: Ukraine
facility: RCI Chernivtsi Regional Clinical Hospital Dept of Surgery Bukovinian SMU
city: Kharkiv
country: Ukraine
facility: CI of PH Kharkiv CCH #2
city: Kharkiv
country: Ukraine
facility: GI L.T.Malaya Therapy National Institute of the NAMS of Ukraine
city: Kirovohrad
country: Ukraine
facility: Treatment-Diagnostic Center of Private Enterprise of PMF Atsynus
city: Kyiv
country: Ukraine
facility: Ukrainian-German Antiulcer Gastroenterological Center BYK-Kyiv LLC
city: Kyiv
country: Ukraine
facility: Kyiv City Clinical Hospital #1
city: Kyiv
country: Ukraine
facility: SI Republican Clinical Hospital of the MOHU Dept of Gastroenterology O.O.Bogomolets NMU
city: Lviv
country: Ukraine
facility: Lviv Regional Clinical Hospital D Halytskyi Lviv NMU
city: Lviv
country: Ukraine
facility: Lviv Municipal City Clinical Hospital #5 Dept of Therapy D.Halytsky Lviv NMU
city: Odessa
country: Ukraine
facility: CI Odesa Regional Clinical Hospital
city: Odessa
country: Ukraine
facility: Communal Institution City Policlinic #20 Cabinet of Gastroenterology
city: Poltava
country: Ukraine
facility: M.V. Sklifosovskyi Poltava RCH Outpatient UMSA HSEIU Ukrainian Medical Stomatological Academy
city: Sumy
country: Ukraine
facility: CI of SRC Sumy RCH Dept of Rheumatology Sumy SU MI
city: Ternopil
country: Ukraine
facility: Ternopil City Communal Emergency Medical Care Hospital
city: Vinnytsia
country: Ukraine
facility: M.I. Pyrogov VRCH Dept of Gastroenterology M.I. Pyrogov VNMU
city: Vinnytsia
country: Ukraine
facility: SRI of Invalid Rehabilitation EST Complex of Vinnytsia M.I.Pyrogov NMU MOHU
city: Zaporizhia
country: Ukraine
facility: SI Branch CH of Zaporizhzhia Station-2 of SE Prydniprovska Railway Dept of Surgery Zaporizhzhia SMU
city: Zaporozhje
country: Ukraine
facility: CI Zaporizhzhia Regional Clinical Hospital of ZRC
city: Birmingham
country: United Kingdom
facility: Queen Elizabeth Hospital
city: Bristol
country: United Kingdom
facility: Bristol Royal Infirmary
city: Exeter
country: United Kingdom
facility: Royal Devon and Exeter Hospital Wonford
city: Glasgow, Scotland
country: United Kingdom
facility: Glasgow Royal Infirmary
city: Glasgow
country: United Kingdom
facility: Queen Elizabeth University Hospital
city: Hull
country: United Kingdom
facility: Hull Royal Infirmary
city: London
country: United Kingdom
facility: Royal London Hospital
city: London
country: United Kingdom
facility: St Marys Hospital
city: Manchester
country: United Kingdom
facility: Manchester Royal Infirmary
city: Manchester
country: United Kingdom
facility: University Hospital of South Manchester NHS Foundation Trust -Wythenshawe Hospital - North West Lung
city: Nottingham
country: United Kingdom
facility: Nottingham University Hospitals Queens Medical Centre
city: Oxford
country: United Kingdom
facility: John Radcliffe Hospital
city: Roxburghshire
country: United Kingdom
facility: Borders General Hospital
city: Shrewsbury
country: United Kingdom
facility: Royal Shrewsbury Hospital
city: Southhampton
country: United Kingdom
facility: Southampton General Hospital
Study officials:
affiliation: Celgene Corporation
name: Guillermo Rossiter, MD
role: STUDY_DIRECTOR
References:
citation: Gold SL, Cohen-Mekelburg S, Schneider Y, Steinlauf A. Perianal Fistulas in Patients With Crohn's Disease, Part 2: Surgical, Endoscopic, and Future Therapies. Gastroenterol Hepatol (N Y). 2018 Sep;14(9):521-528.
citation: Sands BE, Feagan BG, Sandborn WJ, Schreiber S, Peyrin-Biroulet L, Frederic Colombel J, Rossiter G, Usiskin K, Ather S, Zhan X, D'Haens G. Mongersen (GED-0301) for Active Crohn's Disease: Results of a Phase 3 Study. Am J Gastroenterol. 2020 May;115(5):738-745. doi: 10.14309/ajg.0000000000000493.