Clinical trial NCT00522561: Lower Limb Mechanical Characteristics: Effect on Running Mechanics and Energetics
Official title: Lower Limb Mechanical Characteristics: Effect on Running Mechanics and Energetics
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: Healthy volunteers
running
energetic cost
limb mechanical characteristics
contractile components
elastic components
healthy men doing regularly physical activities
Lead sponsor: Centre Hospitalier Universitaire de Saint Etienne
Sponsor class: OTHER
First posted: 2007-08-29
Enrollment: 20
Sex: MALE
Minimum age (years): 20
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: BASIC_SCIENCE

Brief summary: Inter-individual variability in energetic cost of running may be partly explained by lower limbs mechanical characteristics. The transposition of muscle mechanical model with two components (contractile and elastic) to the whole lower limb mechanical behavior analysis during running. The main aim of present investigation is to study the effects of lower limb mechanical characteristic (force, velocity, stiffness) on the energetic cost of running using a lower limb mechanical approach including both contractile and elastic components.Twenty healthy men will run on a treadmill at 12km.h-1 in 8 different 5 min-conditions. Through conditions, stride frequency, sole stiffness and subject's body weight will be changed to allow artificial variations in lower limb mechanical characteristics. Energetic and non-invasive mechanical measurements analysis will be performed to obtain energetic cost of running and to compute force, velocity and stiffness of lower limbs for each condition.

Detailed description: Main aim: Identify the effect of mechanical characteristic induced on lower limbs on the energetic cost of running.

Secondary aim : Minimize the energetic cost of running by lower limb mechanical characteristics optimization.

Eligibility criteria: Inclusion Criteria:

* healthy men being between 20 and 35 years old and doing regularly physical activities
* subjects must be able to run at 12 km/h during 15 minutes in aerobic condition
* not be sedentary and not do running competitions
* be affiliated to a social security system
* Sign a written inform consent

Exclusion Criteria:

* presenting a clinic sign of intolerance to exercise, and particularly to running
* overweight subjects
* having a medical treatment which may interfere with the running quality or with one of the physiological parameters measured
* taking part at the same moment in another medicinal research

Primary outcomes:
measure: the energetic cost of running: the energetic cost (Oxygen consumption by meter covered) is calculated by the ratio of oxygen consumption on the running velocity.
timeFrame: within 4 weeks after inclusion
Secondary outcomes:
Other outcomes:
Locations:
city: Saint-Etienne
country: France
facility: Service de Physiologie clinique et de l'exercice - CHU Saint-Etienne
Study officials:
affiliation: CHU de Saint-Etienne
name: Roger OULLION, MD PhD
role: PRINCIPAL_INVESTIGATOR
References: