Clinical trial NCT05918159: Effects of Sarcopenia on General Health Status in Elderly: a Population-based Study
Official title: Effects of Sarcopenia on the Fall Risk, Body Composition, General Health Status and Quality of Life in Elderly: a Population-based Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Sarcopenia
Sarcopenic Obesity
Frailty
Keywords: Sarcopenia
Quality of Life
Frailty
Muscle Strength
Aging
Body Composition
Postural Balance
Falls
Lead sponsor: Universidade do Algarve
Sponsor class: OTHER
Collaborators: name: European Regional Development Fund
First posted: 2023-06-26
Enrollment: 274
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The participants of this study are people from the community of the Algarve region over 60 years old.

To proceed with the recruitment of participants, the study was disseminated through promotional materials, such as flyers and posters in senior universities, institutions/associations, municipalities and parish councils, sports complexes, among other community spaces in the Algarve region.

A non-probabilistic sampling was used. The sampling process consisted in a first phase of intentional sampling, which allowed recruiting many individuals over 60 years old who met the inclusion and exclusion criteria and in a second phase the sampling process was also carried out using the snowball method.

Brief summary: This is a observational study, that aimed to determine the prevalence of sarcopenia using European Wording Group on Sarcopenia in Older People (EWGSOP) algorithm in a general elderly population in Algarve region (Portugal). Because muscle is metabolically active tissue, sarcopenia may also contribute to the development of some of the metabolic disorders associated with aging. However, the risk factors associated with sarcopenia are poorly understood. Thus, a cross-sectional survey of a sample of 274 elderly adults aged 60 or over, were included in the study. Correlations of sarcopenia with functional level, lipid and glycemic profile, nutritional and physical activity level, fall risk, quality of life, and self-reported comorbidities will be studied.


Eligibility criteria: Inclusion Criteria:

* Minimum age of 60 years;
* Live in the community;
* Independet Gait.

Exclusion Criteria:

* Presence of moderate or severe cognitive impairment;
* Presence of uncontrolled cardiovascular disease and active cancer;
* Use of a pacemaker;
* Use of internal prosthesis.

Primary outcomes:
measure: Prevalence of Sarcopenia in elderly population
timeFrame: 0 Months
measure: Quality of life in elderly population
timeFrame: 0 Months
Secondary outcomes:
measure: Cognitive Assessment
timeFrame: 0 Months
measure: Body mass index (kg/m2) - body composition
timeFrame: 0 Months
measure: Fat Mass (kg and %) - body composition
timeFrame: 0 Months
measure: Fat-Free Mass (kg and %) - body composition
timeFrame: 0 Months
measure: Fat Mass Index (kg/m2) - body composition
timeFrame: 0 Months
measure: Fat-Free Mass Index (kg/m2) - body composition
timeFrame: 0 Months
measure: Muscle Mass Index (kg/m2) - body composition
timeFrame: 0 Months
measure: Total body water (L and %) - body composition
timeFrame: 0 Months
measure: Resistence (Ohms) - body composition
timeFrame: 0 Months
measure: Reactance (Ohms) - body composition
timeFrame: 0 Months
measure: Phase angle (angle) - body composition
timeFrame: 0 Months
measure: Visceral fat (L) - body composition
timeFrame: 0 Months
measure: High-density lipoprotein (HDL) cholesterol (mg/dL) - Lipid Profile
timeFrame: 0 Months
measure: Low-density lipoprotein (LDL) cholesterol (mg/dL) - Lipid Profile
timeFrame: 0 Months
measure: Triglycerides (mg/dL) - Lipid Profile
timeFrame: 0 Months
measure: Total cholesterol (mg/dL) - Lipid Profile
timeFrame: 0 Months
measure: Glicemic Profile in elderly
timeFrame: 0 Months
measure: Inflammatory levels in elderly population
timeFrame: 0 Months
measure: Nutritional level in elderly population
timeFrame: 0 Months
measure: Postural Stability in elderly population
timeFrame: 0 Months
measure: Peak Torque (N/m) of Quadriceps and Hamstring Muscles
timeFrame: 0 Months
measure: Work (N/m) of Quadriceps and Hamstring Muscles
timeFrame: 0 Months
measure: Power (N/m) of Quadriceps and Hamstring Muscles
timeFrame: 0 Months
measure: Peak torque time (s) of Quadriceps and Hamstring Muscles
timeFrame: 0 Months
measure: Force (kg) of Quadriceps and Hamstring Muscles
timeFrame: 0 Months
measure: Time up and Go (TUG) test - Fall risk in elderly population
timeFrame: 0 Months
measure: Modified Falls Efficacy Scale (MFES) - Fall risk in elderly population
timeFrame: 0 Months
measure: Physical Activity level in elderly population
timeFrame: 0 Months
measure: Pain associated with osteoarthritis
timeFrame: 0 Months
measure: Stiffness associated with osteoarthritis
timeFrame: 0 Months
measure: Physical Function associated with osteoarthritis
timeFrame: 0 Months
measure: Functional Level of Lower Limbs
timeFrame: 0 Months
measure: Handgrip strength (HGS)
timeFrame: 0 Months
measure: Identifies the concerns and priorities of older people
timeFrame: 0 Months
Other outcomes:
Locations:
city: Faro
country: Portugal
facility: Marta Botelho
state: Algarve
Study officials:
affiliation: Universidade do Algarve
name: Sandra R Pais, PhD
role: PRINCIPAL_INVESTIGATOR
References: