Clinical trial NCT03571997: Study of Prognostic Factors in Adult Lymphoblastic Lymphoma
Official title: FPLLA-PETHEMA-001: Study of Prognostic Factors in Adult Lymphoblastic Lymphoma
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Lymphoblastic Lymphoma
Lead sponsor: PETHEMA Foundation
Sponsor class: OTHER
First posted: 2018-06-28
Enrollment: 30
Sex: ALL
Minimum age (years): 15
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients\> 15 years diagnosed with ALL and treated with the PETHEMA protocols for ALL

Brief summary: Retrospective observational study with systematic collection of data on filiation (age at diagnosis and sex), clinical data (IPI, ECOG, early response to chemotherapy, overall response to chemotherapy), biological (strain B or T, infiltration of the nervous system central \[CNS\], bone marrow \[MO\], lactate dehydrogenase (LDH) level at the time of diagnosis, as well as genetic patients included in the study, as well as the PETHEMA protocol used in the treatment of same patients The study will review the PETHEMA protocols from 2003 to the present

Detailed description: Retrospective observational study with systematic collection of data on filiation (age at diagnosis and sex), clinical data (IPI, ECOG, early response to chemotherapy, overall response to chemotherapy), biological (strain B or T, infiltration of the nervous system central \[CNS\], bone marrow \[MO\], lactate dehydrogenase (LDH) level at the time of diagnosis, as well as genetic patients included in the study, as well as the PETHEMA protocol used in the treatment of same patients The study will review the PETHEMA protocols from 2003 to the present. Analysis of the main clinical-biological variables as independent risk factors in adult patients (\> 15 years) diagnosed with ALL

Eligibility criteria: Inclusion Criteria:

Patients \>15 years old diagnosed with ALL and treated with the PETHEMA protocols for ALL

Exclusion Criteria:

None

Primary outcomes:
measure: Description pronostic factors
timeFrame: 1 year
Secondary outcomes:
measure: overall survival
timeFrame: 1 year
measure: Progression free survival
timeFrame: 1 year
Other outcomes:
Locations:
city: Oviedo
country: Spain
facility: Hospital Central de Asturias
state: Asturias
city: Terrassa
country: Spain
facility: Hospital Mútua de Terrassa
state: Barcelona
city: Alicante
country: Spain
facility: Hospital General de Alicante
city: Barcelona
country: Spain
facility: H. de la Santa Creu I Sant Pau
city: Barcelona
country: Spain
facility: H. Vall d'Hebron, Barcelona
city: Barcelona
country: Spain
facility: H.Universitari Germans Trias I Pujol de Badalona
city: Barcelona
country: Spain
facility: Hospital Clínic de Barcelona
city: Basurto
country: Spain
facility: Hospital de Basurto
city: Bellvitge
country: Spain
facility: ICO-Duran i Reynals
city: Donostia
country: Spain
facility: Hospital Donostia
city: Girona
country: Spain
facility: H. Univ. de Girona Dr. Josep Trueta (ICO)
city: Lleida
country: Spain
facility: Hospital Arnau de Vilanova (Lleida)
city: Lugo
country: Spain
facility: Hospital Lucus Augusti
city: Madrid
country: Spain
facility: H. Gregorio Marañón
city: Murcia
country: Spain
facility: Hospital General Universitario Morales Messeguer
city: Málaga
country: Spain
facility: Hospital San Pedro de Alcántara.
city: Palma De Mallorca
country: Spain
facility: Hospital Son Espases
city: Palma de Mallorca
country: Spain
facility: Hospital Son Llatzer
city: Pamplona
country: Spain
facility: Complejo Hospitalario de Navarra
city: Sabadell
country: Spain
facility: Parc Taulí
city: Salamanca
country: Spain
facility: H. Univ. de Salamanca
city: Santiago de Compostela
country: Spain
facility: C. H. U. de Santiago
city: Sevilla
country: Spain
facility: Complejo Hosp. Regional Virgen del Rocío
city: Sevilla
country: Spain
facility: Hospital del Valme
city: Tarragona
country: Spain
facility: H. Joan XXIII
city: Valencia
country: Spain
facility: Hoapital La Fe
city: Valencia
country: Spain
facility: Hospital Arnau de Vilanova (Valencia)
city: Valencia
country: Spain
facility: Hospital Universitari Clínic València
Study officials:
References: