Clinical trial NCT06675461: Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
Official title: Randomized Controlled Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Borderline Personality Disorder (BPD)
Keywords: Brief Intervention
Brief Treatment
Treatment
Intervention
Gold Card
Lead sponsor: Centre for Addiction and Mental Health
Sponsor class: OTHER
First posted: 2024-11-05
Enrollment: 180
Sex: ALL
Minimum age (years): 16
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour. There is no established evidence-based brief treatment for patients with BPD in ED settings, however a 4-session treatment for people with personality disorders in ED settings was tested in Australia and showed promising results in reducing health care use and improving symptoms. A recent pilot feasibility randomized controlled trial (RCT) comparing this 4-session treatment to treatment as usual was conducted at the Centre for Addiction and Mental Health and preliminary findings have shown that the treatment is feasible to deliver and acceptable to both patients and clinicians. The proposed fully powered RCT will build on this pilot data to assess the efficacy of delivering this 4-session intervention in the ED for people with BPD who present with suicidal ideation or self-harm with the aim of reducing emergency health care use and improving BPD symptoms, functioning and quality of life.


Eligibility criteria: Inclusion Criteria:

1. Must be deemed to have capacity to provide informed consent;
2. Must sign and date the informed consent form;
3. Stated willingness to comply with all study procedures;
4. Aged 16 or older;
5. Presenting to ED with self-harm and/or suicidal ideation;
6. Meeting criteria for BPD on the International Personality Disorders Examination (IPDE).
7. Endorsing a score of 1 or greater on the Suicide Ideation Attributes Scale (SIDAS).

Exclusion Criteria:

1. Meeting DSM-5 criteria for severe substance use disorder, schizophrenia spectrum disorder or bipolar disorder I mania based on the Structured Clinical Interview for DSM-5 (SCID-5);
2. IQ \< 70 based on the Test of Premorbid Functioning (TOPF).

Primary outcomes:
measure: Suicidal Ideation
timeFrame: 6 Month Follow Up
Secondary outcomes:
measure: Suicidal Ideation
timeFrame: 3 Month Follow Up
measure: Health Care Use
timeFrame: 3 and 6 Month Follow Up
measure: Borderline Personality Disorder Symptoms
timeFrame: 3 and 6 Month Follow Up
measure: Self-Harm Behavior
timeFrame: 3 and 6 Month Follow Up
measure: Emotion Regulation
timeFrame: 3 and 6 Month Follow Up
measure: Depressive Symptoms
timeFrame: 3 and 6 Month Follow Up
measure: Functioning
timeFrame: 3 and 6 Month Follow Up
measure: Quality of Life
timeFrame: 3 and 6 Month Follow Up
Other outcomes:
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