Clinical trial NCT04795232: Recovery Kinetics Following Change of Direction Training
Official title: Recovery Kinetics Following Change of Direction (COD) Training in Soccer: Implications for Different COD Angles
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Skeletal Muscle Damage
Keywords: change of direction training
recovery
soccer
performance
Lead sponsor: University of Thessaly
Sponsor class: OTHER
First posted: 2021-03-12
Enrollment: 10
Sex: MALE
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: OTHER

Brief summary: This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single change of direction (COD) training session in competitive soccer players. The impact of COD degrees will be also examined by comparing a 45o vs. 90o COD training session. Ten male soccer players will perform a COD45 \[A single training session including 2x(10x \~27.6m) sprints with two 45o COD in each sprint\], a COD90 \[A single training session including 2x(10x \~21.2m) sprints with two 90o COD in each sprint\] and a Control trial (No intervention included, only daily measurements) in randomized, repeated measures, crossover design. Assessments related to skeletal muscle damage, neuromuscular fatigue and performance will be performed prior to training session and daily for three consecutive days post-training, in each trial.

Detailed description: Ten male soccer players will be included in this study. Participants will be initially informed about the aim of study as well as the associated risks and benefits and subsequently will provide their signed consent form. At baseline, they will undergo assessment of their anthropometrics (i.e. body mass and body height), body composition (by DXA), physical conditioning status \[maximal oxygen consumption (VO2max), Yo-Yo Intermittent Endurance test level 2 and Yo-Yo Intermittent Recovery test level 2\] and daily dietary intake. Thereafter, they will participate in two experimental trials and one control trial in a randomized, crossover, repeated measures design: i) COD45: Participants in this trial will perform a COD training session consisted of 2 sets of 10 x \~27.6m sprints with two 45o COD in each sprint and a resting period of 16 sec and 2:20 min between sprints and sets, respectively, ii) COD90: Participants in this trial will perform a COD training session consisted of 2 sets of 10 x \~21.2m sprints with two 90o COD in each sprint and a resting period of 16 sec and 2:20 min between sprints and sets, respectively, iii) Control: Participants in this trial will only participate in daily assessments to control for day to day variability in the depended variables (they will not receive any intervention). Prior to each trial, participants will provide a resting blood sample (for the determination of blood lactate, white blood cell count and creatine kinase activity) and undergo assessment of their delayed onset of muscle soreness (DOMS), maximal voluntary isometric contraction (MVIC), countermovement jump \[will be assessed using two force platforms at 1000 Hz and electromyography instrumentation (EMG)\], isokinetic peak torque of knee extensors and flexors (will be assessed on an isokinetic dynamometer), agility (will be assessed using the Illinois test), 10m and 30m sprint time (will be assessed by using light cells) and repeated sprint ability (5x30m sprints will be performed with 25 sec rest in-between). In COD45 and COD90 experimental trials, a blood sample will be collected immediately post-training for the determination of blood lactate concentration while assessment of DOMS, MVIC and countermovement jump will be performed at 1, 2 and 3 hours post-training. In all trials assessment of DOMS, MVIC, countermovement jump (CMJ), isokinetic peak torque, agility and sprinting performance as well as determination of creatine kinase activity and white blood cell count will be performed at 24, 48 and 72 hours post-training. A 7-day wash out period will applied between trials.

Eligibility criteria: Inclusion Criteria:

* Soccer players participating in at least 5 training sessions per week and 1official match
* Participation at a competitive level for at least 4 years
* Free of musculoskeletal injuries
* No use of ergogenic supplements or medication
* Non-smokers

Exclusion Criteria:

* Musculoskeletal injury
* Use of alcohol, caffeine and any type of ergogenic supplements or medication during the course of the study

Primary outcomes:
measure: Change in creatine kinase activity
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in white blood cell count
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in delayed onset of muscle soreness
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in isometric peak torque
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in fatigue index of maximal voluntary isometric contraction during 10 seconds
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in isokinetic peak torque of knee extensors
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in isokinetic peak torque of knee flexors
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in countermovement jump height
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in ground reaction force during countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in peak power during countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in mean power during countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in vertical stiffness during countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in peak rate of force development during countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in peak normalized electromyography (EMG) during the eccentric and concentric phases of the countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in mean normalized electromyography (EMG) during the eccentric and concentric phases of the countermovement jump
timeFrame: At baseline, at 1, 2, 3, 24, 48 and 72 hours after change of direction training session
measure: Change in repeated sprint ability
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in sprint time of 10m
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in sprint time of 30m
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in agility
timeFrame: At baseline, at 24, 48 and 72 hours after change of direction training session
measure: Change in field activity during the change of direction training session
timeFrame: During the change of direction training session
measure: Change in heart rate during the change of direction training session
timeFrame: During the change of direction training session
measure: Change in blood lactate concentration
timeFrame: At baseline and immediately post change of direction training session
Secondary outcomes:
measure: Body mass
timeFrame: At baseline
measure: Body height
timeFrame: At baseline
measure: Body fat
timeFrame: At baseline
measure: Lean body mass
timeFrame: At baseline
measure: Maximal oxygen consumption (VO2max)
timeFrame: At baseline
measure: Yo-Yo Intermittent Endurance Test level 2 performance
timeFrame: At baseline
measure: Yo-Yo Intermittent Recovery Test level 2 performance
timeFrame: At baseline
measure: Dietary intake
timeFrame: At baseline
Other outcomes:
Locations:
city: Trikala
country: Greece
facility: SMART LAB, Department of Physical Education and Sports Science, University of Thessaly.
city: Trikala
country: Greece
facility: SmArT LABORATORY, SCHOOL OF PHYSICAL EDUCATION & SPORTS SCIENCES, UNIVERSITY OF THESSALY
Study officials:
affiliation: University of Thessaly, Department of Physical Education and Sport Science
name: Ioannis G Fatouros, Prof
role: STUDY_DIRECTOR
References: