Clinical trial NCT06536907: Decompression of Odontogenic Cysts
Official title: The Effect of Decompression on Histologic Diagnoses of Cystic Jaw Lesions
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Odontogenic Cysts
Keratocysts of the Jaw
Cysts Dental
Pathology
Keywords: biopsy
diagnosis
keratocysts
odontogenic cysts
oral pathology
surgical decompression
Lead sponsor: Akdeniz University
Sponsor class: OTHER
First posted: 2024-08-05
Enrollment: 39
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study included patients with a histologic diagnosis of an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery.

Brief summary: The aim of this case-control study is to evaluate the effects of decompression of cystic jaw lesions by means of comparing pre- and post-decompression histologic findings.

The main question it aims to answer is:

Does decompression of cystic jaw lesions alter the histologic diagnosis?

A retrospective analysis was performed based on the comparison of initial and final histologic diagnoses of patients with an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery.

Detailed description: The study included patients with a histologic diagnosis of an odontogenic cystic lesion, that was surgically treated with decompression followed by a definitive surgery. The study was carried out retrospectively by means of evaluating records, surgical and histologic reports of patients. Pre- and post-decompression histologic findings were compared in effort to understand if decompression leads to alteration in histologic character and change in diagnoses of lesions.

Eligibility criteria: Inclusion Criteria:

* To have an initial diagnosis of an odontogenic cystic jaw lesion confirmed with an incisional biopsy.
* The patients must have undergone decompression and, enucleation or enucleation and peripheral ostectomy after decompression period.

Exclusion Criteria:

* Previously treated patients
* The patients with missing information in medical and/or dental records
* The patients who did not adhere to follow-up protocol

Primary outcomes:
measure: Change in histologic diagnosis following decompression (yes/no)
timeFrame: A decompression period ranging between 2 and 15 months
Secondary outcomes:
Other outcomes:
Locations:
city: Antalya
country: Turkey
facility: Akdeniz University
Study officials:
References:
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