Clinical trial NCT05649397: Effects of Cervical Spine Manipulation in Patients With Mechanical Neck Pain
Official title: Effects of Cervical Spine Manipulation on Proprioception, Blood Pressure and Respiratory Rate in Patients With Mechanical Neck Pain
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Neck Pain
Keywords: pain
proprioception
blood pressure
respiratory rate
cervical manipulation
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-12-14
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Mechanical neck pain is known as one of the most common disorders in musculoskeletal system. In elderly population, prevalence of neck pain ranges up to 38% while point prevalence and lifetime prevalence ranges from 6% to 22% and 14.2% to 71% respectively . Neck pain is defined by the international association for the study of pain as: "Pain perceived as arising from anywhere within the region bounded superiorly by superior nuchal line, inferior by transverse line through the tip of first thoracic spinous process, and laterally by sagittal plane tangential to the lateral border of neck" . There are variable causes of neck pain like trauma, infections, inflammatory conditions, musculoskeletal conditions, rheumatic diseases, and congenital diseases . There are varying degrees of disability and activity limitation caused by neck pain, like work productivity reduction and decrease quality of life . People who have a sedentary lifestyle, poor occupational postures, students with poor posture, people involved in occupation like computer programming, clerical job workers and desk job works are more likely to suffer from mechanical neck pain . Most common cause of mechanical neck pain is muscle tightness, Upper trapezius and levator scapulae are the most involved muscles

Detailed description: Neck pain can over time negatively affect the central processing of any afferent input received because it can create a disturbance in the proprioceptive input to the Central Nervous System. Vuillerme stated that cervical muscle proprioceptors are stimulated by painful electrical stimuli. Therefore, joint proprioception can be affected in patients with mechanical neck pain .

The conservative management of mechanical neck pain includes many treatment options like electrotherapy which includes moist heat, Transcutaneous Electrical Nerve Stimulation therapy and different manual therapy options like cervical and thoracic mobilization and manipulation, Natural Apophyseal Glides and Sustained Natural Apophyseal Glides, Cyriax technique, manual pressure release, ischemic compression and proprioceptive neuromuscular facilitation. Postural reeducation and strength training of weak muscle group has beneficial effects. Joint mobilization and manipulation are widely used as a treatment for mechanical neck pain, as cervical mobilizations which are low velocity passive oscillatory movements are used by 90% of physiotherapist and chiropractors to treat people with neck pain.

Eligibility criteria: Inclusion Criteria:

* Patients with non-radiating neck pain of moderate intensity scoring 4-8 on the numeric pain rating scale (NPRS)
* Have a Neck Disability Index (NDI) score of 20% or greater (10 points or greater on a 0-to-50 scale)
* Patients who have cervical joint position error greater than 7.1 cm or 4.5 degrees

Exclusion Criteria:

* Patients with a positive history of trauma, fracture or surgery of the cervical spine .
* anatomical cervical spine abnormality
* presented with any neurological signs
* history of benign paroxysmal positional vertigo
* Neck pain with radiation to the arm and upper extremity .
* Diagnosed cases of torticollis, and scoliosis
* History of osteoporosis, Any cardiac disorder
* had participated in a neck exercise program in the past 6 months .

Primary outcomes:
measure: Joint position sense test
timeFrame: four weeks
measure: Digital sphygmomanometer
timeFrame: four weeks
measure: Respiratory rate measurement
timeFrame: four weeks
measure: NPRS (Numeric Pain Rating Scale).
timeFrame: four weeks
measure: NDI (U) (Neck Disability Index)
timeFrame: four weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Riphah international hospital Sihala
state: Punjab
Study officials:
affiliation: Riphah International University
name: maria Khalid, MSOMPT
role: PRINCIPAL_INVESTIGATOR
References: