Clinical trial NCT05597059: The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department (PREKEYDIA)
Official title: The Diagnostic Value of the First Clinical Impression of Patients Presenting to the Emergency Department
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Emergencies
Lead sponsor: Kepler University Hospital
Sponsor class: OTHER
First posted: 2022-10-27
Enrollment: 1506
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adults presenting to the emergency department.

Brief summary: Finding a diagnosis for acutely ill patients places high demands on emergency medical personnel. While anamnesis and clinical examination provide initial indications and allow a tentative diagnosis, both laboratory chemistry and imaging tests are used to confirm (or exclude) the tentative diagnosis. The more precise and targeted the additional laboratory chemical or radiological diagnosis, the more quickly and economically the causal treatment of the emergency patient can be initiated.

One examination modality, which in addition to the medical history and clinical examination, could quickly provide information about the condition of the patient, their clinical picture and severity of illness, is the first clinical impression of the patient (so-called "first impression" or "end-of-bed view"). This describes the first sensory impression that the medical staff gathers from a patient. This includes visual (e.g., facial expression, gait, breathing), auditory (e.g., voice pitch, shortness of breath when speaking), and olfactory (e.g., smell of exhaled air, body odor) impressions. Clinical practice shows that a great deal of important additional information can be gathered through this first clinical impression, which, together with the history and clinical examination of the emergency patient, provides valuable clues to the underlying condition.

To date, however, only scattered data and study results exist in the medical literature on the value of the first clinical impression in the care of emergency patients. In the present prospective observational study, the study attempts to evaluate the predictive value of the first clinical impression in identifying a leading symptom and other important clinical parameters.


Eligibility criteria: Inclusion Criteria:

* Patients presenting to the emergency department between 2019-09-01 and 2020-02-28.

Exclusion Criteria:

* None.

Primary outcomes:
measure: AUROC for Classification of Shortness of Breath
timeFrame: 2019-09-01 to 2020-02-28
measure: AUROC for Classification of Extremity Pathologies
timeFrame: 2019-09-01 to 2020-02-28
measure: AUROC for Classification of Abdominal Pain
timeFrame: 2019-09-01 to 2020-02-28
measure: AUROC for Classification of Urological Pathologies
timeFrame: 2019-09-01 to 2020-02-28
measure: AUROC for Classification of Chest Pain
timeFrame: 2019-09-01 to 2020-02-28
measure: AUROC for Classification of Back Pain
timeFrame: 2019-09-01 to 2020-02-28
Secondary outcomes:
measure: AUROC for Classification of Hospital Admission
timeFrame: 2019-09-01 to 2020-02-28
measure: Confusion Matrix
timeFrame: 2019-09-01 to 2020-02-28
measure: Descriptive Statistics
timeFrame: 2019-09-01 to 2020-02-28
Other outcomes:
Locations:
city: Linz
country: Austria
facility: Kepler University Hospital
state: Upper Austria
Study officials:
References: