Clinical trial NCT05739370: Internet Delivered Psychotherapy for Older Adults
Official title: Internet Delivered Psychotherapy for Older Adults: Development and Evaluation of an Online Problem-Solving Therapy Program for Depression.
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Depression in Old Age
Depression, Anxiety
Keywords: Online Psychotherapy
Lead sponsor: University of Calgary
Sponsor class: OTHER
Collaborators: name: Hotchkiss Brain Institute, University of Calgary
First posted: 2023-02-22
Enrollment: 13
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The goal of this mixed-methods, single-arm intervention study is to develop and evaluate a new internet-delivered psychotherapy option called Ger-iPST in older adults with symptoms of depression.

The overall aim of this project is to improve access to psychotherapy for older adults by developing, adapting and implementing a new internet-based treatment option, Ger-iPST. Towards this aim, our objectives are to:

1. Examine the preliminary effectiveness of Ger-iPST for symptoms of depression.
2. Examine barriers and facilitators to the use of Ger-iPST.

Participants will be asked to complete 8 weekly online therapy modules (Ger-iPST) through the Online Psycho Therapy Tool (OPTT); each module takes 45-60 minutes, and an extra 20-30 on weekly homework. Caregivers will be invited to assist participants if required.

Homework exercises are submitted through the platform, and a clinician trained in PST l will provide personalized, asynchronous online feedback. Participants will receive a weekly phone call from a research assistant to support any technical issues with completing the online modules. Following completion of the Ger-iPST modules, participants will be interviewed to provide feedback on acceptability and barriers and facilitators to the use of Ger-iPST.

Detailed description: Background \& Rationale: Many older adults in the community experience symptoms of depression, but few receive adequate treatment, which can include medications or psychotherapy (talk therapy). Problem-Solving Therapy (PST) is a very effective psychotherapy for depression, but psychotherapy such as PST is usually not available to older adults due to high cost, limited resources, and other barriers such as lack of transportation. Internet-delivered psychotherapy is a more accessible option that can be as effective as traditional face-to-face therapy.

Research Question and Objectives: The overall aim of this project is to improve access to psychotherapy for older adults by developing, adapting and implementing a new evidence-based treatment option, Ger-iPST. Towards this aim, our objectives are to:

1. Develop the Ger-iPST intervention.
2. Examine the effectiveness and implementation of Ger-iPST: 2a. Measure the preliminary effectiveness of symptoms of depression in older adults; 2b. Explore barriers and facilitators to the use of Ger-iPST among participants and experiences with implementation.

Methods: The investigator will implement and evaluate the effectiveness of Ger-iPST in Calgary, Alberta. Ger-iPST is an 8-week online psychotherapy program with online therapist support based on Problem Solving Therapy (PST), a proven and safe psychotherapy for depression in older adults. Ger-iPST will be tailored to the specific needs of older adults with relevant content (e.g. modules using aging-related examples); process adaptations (e.g. more repetition); and digital usability modifications. Participants will complete weekly online Ger-iPST modules, and the investigator will measure symptoms of depression before, during, and after completing the program. The investigator will also collect information on symptoms of anxiety, quality of life, and disability. The Ger-iPST intervention will be hosted on an existing, secure, cloud-based psychotherapy platform, Online PsychoTherapy Tool (OPTT). All quantitative data collection will occur using questionnaires on the platform. Following completion of the Ger-iPST modules, participants will be interviewed to provide feedback on acceptability and barriers and facilitators to the use of Ger-iPST. These results will be used to improve and adapt the resource to best suit the needs of older adults.

Treating depression improves functioning, emotional well-being, and overall health among older adults. Many older adults prefer psychotherapy over (or in addition to) medication for the treatment of depression, and given that a growing number of older adults use the internet, internet-delivered therapy has the potential to greatly improve access to treatment for older adults with depression.

Eligibility criteria: Inclusion Criteria:

* Individuals who are 65 years or older
* Presenting with a primary complaint of depression and a Patient Health Questionnaire (PHQ)-9 score \> 5
* English Speaking
* Residents of Alberta
* Have internet access

Exclusion Criteria:

* Individuals with acute safety concerns (e.g.suicidal ideation), psychotic symptoms, moderate cognitive impairment (Montreal Cognitive Assessment(MoCA) \< 21) or currently receiving psychotherapy

Primary outcomes:
measure: Measure the effectiveness for symptoms of depression in older adults.
timeFrame: Baseline, mid-point (4-weeks) and after completing the program (8-weeks).
Secondary outcomes:
measure: Examine implementation outcomes - Anxiety symptoms.
timeFrame: 8 weeks via OPTT.
measure: Examine implementation outcomes - Disability Assessment.
timeFrame: 8 weeks via OPTT.
measure: Examine implementation outcomes - Quality of life.
timeFrame: 8 weeks via OPTT.
measure: Examine implementation outcomes - Usability.
timeFrame: 8 weeks via OPTT.
measure: Explore barriers and facilitators experienced with implementation.
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Calgary
country: Canada
facility: Department of Psychiatry, Cumming School of Medicine, University of Calgary
state: Alberta
Study officials:
affiliation: University of Calgary
name: Julia Kirkham, MD
role: PRINCIPAL_INVESTIGATOR
References: