Clinical trial NCT04948905: Assessment of Sense of Identity in Patients Diagnosed With Borderline Personality Disorder. A Pilot Study
Official title: Assessment of Sense of Identity in Patients With a Diagnosis of Borderline Personality Disorder Through Autobiographical Memory and the Contents of Self-defining Memories, Compared to a Group of Healthy Individuals. A Pilot Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Borderline Personality Disorder
Keywords: Personality Disorder,
Borderline
Psychology
Self-Identity
Lead sponsor: Centre Hospitalier Universitaire de Nīmes
Sponsor class: OTHER
First posted: 2021-07-02
Enrollment: 60
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 30 patients diagnosed as having Bordeline Personality Disorder 30 healthy controls recruited from a poster Campaign within the various departments of Nîmes University Hospital, France.

Brief summary: One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity. Autobiographical memory is closely linked to the development and maintenance of a coherent, stable sense of self. It enables the individual to understand who he or she is. The investigators hypothesize that individuals diagnosed with Borderline Personality Disorder have a less coherent, stable sense of the self than healthy controls. The aim of the study is therefore to compare the sense of identity between a group of patients diagnosed with Borderline Personality Disorder and a group of healthy individuals (without Borderline Personality Disorder ).

This can be measured by evaluating the content of the self-defining memory using the Self-Defining Memory scale.


Eligibility criteria: Inclusion Criteria:

* Subject must have given written consent
* Subject affiliated or beneficiary of a health insurance plan.
* Adult subjects between 25 and 55 years of age
* Oral and written mastery of the French language

Inclusion criteria for the borderline group:

* Subject diagnosed as having borderline personality disorder according to the DSM IV classification

Exclusion criteria for the borderline group:

* Patients without diagnosis of borderline personality disorder according to the DSM IV classification after taking the SCID II (Structured Clinical Interview for DSM-III-R Axis II Disorders) test

Exclusion criteria for the control group:

* Subjects considered Borderline after taking the SCID II (Structured Clinical Interview for DSM-III-R Axis II Disorders) test
* Subjects with a score above 8 on the HADS questionnaire corresponding to questionable symptomatology for anxiety and depressive symptoms.

General exclusion Criteria:

* Subjects under court protection, guardianship or curatorship
* Subjects for whom it is impossible to give informed information
* Subjects participating in a Category 1 or 2 RIPH in the 3 months prior to the study
* Subject refusing to give written consent
* Presence of known neurological disease
* Pregnant or breastfeeding women

Primary outcomes:
measure: Sense of Identity in patients diagnosed with Borderline Personality Disorder according to the results of the Self-Defining Memory questionnaire.
timeFrame: Day 7
measure: Sense of Identity in healthy controls according to the results of the Self-Defining Memory questionnaire.
timeFrame: Day 7
Secondary outcomes:
measure: Self-coherence of self-defining memories in patients diagnosed with Borderline Personality Disorder
timeFrame: Day 7
measure: Self-coherence of self-defining memories in healthy controls
timeFrame: Day 7
measure: Phenomenological details of self-defining memories in patients diagnosed with Borderline Personality Disorder
timeFrame: Day 7
measure: Phenomenological details of self-defining memories in healthy controls
timeFrame: Day 7
measure: Traumas undergone in patients diagnosed with Borderline Personality Disorder: Frequency
timeFrame: Day 7
measure: Traumas undergone in healthy controls: Frequency
timeFrame: Day 7
measure: Traumas undergone in patients diagnosed with Borderline Personality Disorder: Type
timeFrame: Day 7
measure: Traumas undergone in healthy controls: Type
timeFrame: Day 7
Other outcomes:
measure: Age of patients diagnosed with Borderline Personality Disorder
timeFrame: Day 0
measure: Age of healthy controls
timeFrame: Day 0
measure: Sex of patients diagnosed with Borderline Personality Disorder
timeFrame: Day 0
measure: Sex of healthy controls
timeFrame: Day 0
measure: Level of education of patients diagnosed with Borderline Personality Disorder
timeFrame: Day 0
measure: Level of education of healthy controls
timeFrame: Day 0
measure: Type of trauma undergone by patients diagnosed with Borderline Personality Disorder
timeFrame: Day 7
measure: Type of trauma undergone by healthy controls
timeFrame: Day 7
measure: Contents of the self-defining memory in patients diagnosed with Borderline Personality Disorder
timeFrame: Day 7
measure: Contents of the self-defining memory in healthy controls
timeFrame: Day 7
measure: Other observations in patients diagnosed with Borderline Personality Disorder
timeFrame: Day 7
measure: Other observations in healthy controls
timeFrame: Day 7
Locations:
city: Nîmes
country: France
facility: Nîmes University Hospital
state: Gard
Study officials:
affiliation: Psychiatric Unit, Nîmes University Hospital, France
name: Jorge LOPEZ-CASTROMAN, Prof.
role: PRINCIPAL_INVESTIGATOR
affiliation: Montpellier University III, Laboratoire Epsylon, Route de Mende, 34090 Montpellier, France
name: Stéphane RAFFARD, Prof.
role: STUDY_DIRECTOR
References:
citation: Moffitt KH, Singer JA. Continuity in the Life Story: Self-Defining Memories, Affect, and Approach/Avoidance Personal Strivings. Journal of Personality.1994; 62(1), 21-43
citation: Singer, J. A., & Moffitt, K. H. An experimental investigation of specificity and generality in memory narratives. Imagination, Cognition and Personality. PsycINFO Database Record (1991-1992)11(3), 233-257.
citation: Bluck S, Alea N. Crafting the TALE: construction of a measure to assess the functions of autobiographical remembering. Memory. 2011 Jul;19(5):470-86. doi: 10.1080/09658211.2011.590500.
citation: Johnson MK, Foley MA, Suengas AG, Raye CL. Phenomenal characteristics of memories for perceived and imagined autobiographical events. J Exp Psychol Gen. 1988 Dec;117(4):371-6.
citation: Bernstein, D. P., Fink, L., Handelsman, L., & Foote, J. Childhood Trauma Questionnaire (CTQ) [Database record].(1994) APA PsycTests. https://doi.org/10.1037/t02080-000
citation: Spitzer, Robert L, Williams Janet BW, Gibbon Miriam, First Michael B, Structured Clinical Interview for DSM-III-R Axis II Disorders,(SCID-II), Washington, D.C.: American Psychiatric Press, Inc., 1990