Clinical trial NCT06058507: "Carotid Web Incidence and Radiological Classification, Determination of Its Relationship With Ischemic Stroke"
Official title: "The Incidence of Carotid Web and Its Radiological Classification, Determination of Its Relationship With Ischemic Stroke by Evaluating the Clinical Data and Vascular Risk Factors of Carotid Web Cases"
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Stroke
Transient Ischemic Attack
Carotid Artery Diseases
Keywords: carotid web
ischemic stroke
transient ischemic atack
Lead sponsor: Suleyman Demirel University
Sponsor class: OTHER
First posted: 2023-09-28
Enrollment: 31
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients over 18 years of age who underwent carotid CTA and/or DSA imaging with the preliminary diagnosis of cerebrovascular disease and a carotid web was detected.

Brief summary: In our research, we aim to increase awareness on this issue by classifying the frequency of carotid webs and their radiological classification; Evaluating the clinical data and vascular risk factors of carotid web cases and determining their relationship with ischemic stroke and determining the measures that can be taken for future optimal treatment.

We aimed to contribute to their approach.

Detailed description: Carotid web is a thin membrane-like tissue that extends from the wall to the lumen of the carotid artery bulb, identified radiologically. It is considered that stroke may be related to altered hemodynamics, blood stasis and fibrin-based clot embolization mechanisms in the distal carotid web. Radiologically, in DSA and CTA, there is a thin membrane-like intraluminal filling defect extending along the posterior carotid wall in oblique-sagittal sections and a corresponding defect in axial sections.

It is seen as a thin septum; There is no study on its classification in the literature. Determination of the incidence of carotid web, determination of its relationship with ischemic stroke / TİA, Facilitating distinctions such as dissection etc. by making radiological classification is important in terms of increasing awareness on this issue and early diagnosis. Demonstrating the relationship between carotid webs, which are shown as a cryptogenic cause of stroke, and vascular risk factors and taking protective measures against them will be effective in preventing strokes. In our research, we aim to increase awareness on this issue by classifying the frequency of carotid webs and their radiological classification; We aimed to evaluate the clinical data and vascular risk factors of carotid web cases, determine their relationship with ischemic stroke, and determine the precautions that can be taken to contribute to future optimal treatment approaches.

Eligibility criteria: Inclusion Criteria:

* Being over 18 years old

  * Having a preliminary diagnosis of cerebrovascular disease
  * Having carotid CTA and/or DSA imaging performed

Exclusion Criteria:

* Being under 18 years of age
* Patients who cannot undergo CTA and/or DSA imaging due to the risk of contrast material allergy or renal failure.
* Patients for whom consent for imaging cannot be obtained by the patient and their relatives and for whom CTA/DSA examination is not required in terms of etiology

Primary outcomes:
measure: ischemic stroke
timeFrame: 1 year
Secondary outcomes:
measure: transient ischemic atack
timeFrame: 1 year
Other outcomes:
Locations:
city: Isparta
country: Turkey
facility: Suleyman Demirel University
Study officials:
affiliation: Suleyman Demirel University
name: ekin EB baylam yirmibeş
role: PRINCIPAL_INVESTIGATOR
References: