Clinical trial NCT05151432: Effect of Pulsed Electromagnetic Field and Pulsed Ultrasound in Treating Knee Osteoarthritis
Official title: Combined Effect of Pulsed Electromagnetic Field and Pulsed Ultrasound Therapy in Treating Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteo Arthritis Knee
Ultrasound Therapy; Complications
Lead sponsor: Horus University
Sponsor class: OTHER
First posted: 2021-12-09
Enrollment: 80
Sex: ALL
Minimum age (years): 40
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will be carried out to combine the effect of PEMF and PUT on pain, function, and ROM in patients with knee OA.

Detailed description: Osteoarthritis (OA) is one of the most frequent illnesses in the world, affecting the knee joint in particular. Osteoarthritis of the knee is the most common cause of physical limitations and a decline in quality of life. OA of the knee affects 250 million individuals worldwide (3.6 percent of the population). According to the World Health Organization's study on the global burden of illness, knee OA is expected to become the eighth-most

Ultrasound is one of the most often utilized and misunderstood treatment techniques. Ultrasound can help in the treatment or rehabilitation of musculoskeletal problems when utilized appropriately. When it is administered wrongly, however, the therapy provides little benefit at best, and at worst, the desired physiological effects are restricted or hindered.

Electrotherapy is frequently used for the treatment of different musculoskeletal disorders, The most common types of electrotherapy are ultrasound (US), iontophoresis, laser therapy, electromagnetic therapy, and transcutaneous electrical nerve stimulation (TENS). To our knowledge, no previous clinical trials have combined the effectiveness of PEMF and PUST in the treatment of knee OA. Therefore, this study will be conducted to combine the efficacy of PEMF and PUST in the treatment of knee osteoarthritis.

Eligibility criteria: Inclusion Criteria:

1. Subjects diagnosed with moderate unilateral knee OA according to the American College of Rheumatology criteria

   * Morning stiffness
   * Crepitus on knee motion
   * Bony tenderness
   * No palpable warmth.
2. a population of individuals (45-55 years old).
3. patients are not obese their body mass index (BMI) will be\> 30kg/ m2.
4. with a diagnosis grade 2 radiographic severity according to the Kellgren/Lawrence scale. grading scale The severity of the disease was radiologically evaluated by an orthopedic knee specialist.

Exclusion Criteria:

Patients with the following criteria will be excluded from participating in this study:

1. if they had received an intra-articular injection of hyaluronic acid or corticoids during the six months prior to the study.
2. if they had a clinical history of orthopedic knee surgery, a skin disorder.
3. cardiovascular diseases, such as acute myocardial infarction, during the previous month, or uncontrolled arterial hypertension, acute-phase respiratory conditions.
4. or if they had been receiving another kind of physiotherapeutic treatment.

Primary outcomes:
measure: Pain intensity
timeFrame: at baseline and after 4 weeks of intervention
measure: Dynamic balance
timeFrame: at baseline and after 4 weeks of intervention
measure: Range of motion of knee
timeFrame: at baseline and after 4 weeks of intervention
Secondary outcomes:
measure: Pain, Stiffness and function
timeFrame: at baseline and after 4 weeks of intervention
measure: Walking ability
timeFrame: at baseline and after 4 weeks of intervention
Other outcomes:
Locations:
city: Damietta
country: Egypt
facility: Outpatient clinic, Faculty of Physical Therapy, Horus University, Egypt
Study officials:
affiliation: Horus University in Egypt
name: Ahmed Fayez, Demonstrator
role: PRINCIPAL_INVESTIGATOR
References: