Clinical trial NCT03998397: Self-estimates and Objective Blood Alcohol Concentration in Emergency Department
Official title: Self-estimates and Objective Measurement of Blood Alcohol Concentration in Patients With Alcohol Intoxication Presenting to an Emergency Department
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Alcohol Use Disorder
Blood Alcohol Content
Keywords: blood alcohol concentration
Emergency Department
Alcohol use disorders
Lead sponsor: Centre Hospitalier Universitaire, Amiens
Sponsor class: OTHER
First posted: 2019-06-26
Enrollment: 34
Sex: ALL
Minimum age (years): 15
Maximum age (years): 64
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Many patients presenting in Emergency Department (ED) present alcohol acute intoxication. Some previous studies in general population found that young people under- or over-estimated of blood alcohol concentration (BAC). The hypothesis of the study is that self-estimation of BAC by the patient is under-estimated. Moreover, comparing self-estimation of BAC and objective measure of BAC, which is routinely performed in ED, could increase in patients the awareness of the disorders, increase motivation to change of the patient, and increase the rates of seeking-treatment six months after the first evaluation, in particular in patients with alcohol use disorders.

To the investigators knowledge, there is no study investigating self-estimation, compared to objective measurement of blood alcohol concentration in patients with alcohol intoxication presenting to an Emergency Department (ED). The study will assess blood alcohol concentration and self-estimates of BAC, using the Subjective Effects of Alcohol Scale for Measuring Subjective Response to Alcohol in 100 patients with or without alcohol use disorders according to DSM-5 classification (using MINI scale and Alcohol Use Disorders Identification Test (AUDIT)


Eligibility criteria: Inclusion Criteria:

* Patients admitted in Emergency Department while intoxicated will be included in the study, including patients with or without alcohol use disorders according to DSM-5 classification.
* aged 15-64 years old
* patients who will be orally informed and receive a written summary
* blood alcohol concentration of 60mg/dl or higher
* Patients not opposed to participating in the study, who have received an oral and written information

Exclusion Criteria:

* Drug intoxication (cannabis, opiates, amphetamines, cocaine), psychotropic medication intoxication (benzodiazepines, antipsychotics), primary neurologic conditions, mental retardation, dementia, amnestic disorders, mental disorders due to a general, medical condition and substance-induced psychotic disorders.

Primary outcomes:
measure: Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration
timeFrame: Day =0 (day of patient inclusion)
Secondary outcomes:
measure: Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient with alcohol use disorders
timeFrame: Day =0 (day of patient inclusion)
measure: Mean change between real blood alcohol concentration and self-estimated blood alcohol concentration in patient without alcohol use disorders
timeFrame: Day =0 (day of patient inclusion)
measure: Measure motivation to change during the first interview at the Emergency Department
timeFrame: Day =0 (day of patient inclusion)
measure: Measure motivation to change six months following the first interview at the Emergency Department
timeFrame: six months following the first interview at the Emergency Department
Other outcomes:
Locations:
city: Amiens
country: France
facility: CHU Amiens
Study officials:
affiliation: CHU Amiens
name: Alain Dervaux, Pr
role: PRINCIPAL_INVESTIGATOR
References: