Clinical trial NCT04320732: Risk Factors for Community- and Workplace Transmission of COVID-19
Official title: Risk Factors for Community- and Workplace Transmission of COVID-19
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Coronavirus
Lead sponsor: Oslo University Hospital
Sponsor class: OTHER
Collaborators: name: Age Labs AS
First posted: 2020-03-25
Enrollment: 250000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The study will be a combined retrospective and prospective case-control study based on a combined electronic consent form and questionnaire that the study groups will fill in using a smartphone and electronic identification.

The groups that will be included are:

* Hospitalized and non-hospitalized patients/persons with COVID-19 at all stages of the disease and after the disease
* Hospitalized patients without COVID-19
* Healthcare personal or other groups with an increased risk of COVID-19
* Healthy volunteers

Probability sampling will be conducted, but not solely.

Brief summary: The project is an epidemiological observational study based on an electronic questionnaire on risk factors for COVID-19 in the community and healthcare setting.

Detailed description: Summary The data collected will identify real-life risk factors for getting the COVID-19 diagnosis.

The Oslo University Hospital/University of Oslo web-based solution "nettskjema" will be used to collect data and consent forms.

The impact of knowing the risk factors for COVID-19 is tremendous because it can enable governments to conduct more targeted public health measurements than today to reduce the spread of the virus.

Detailed description Research into an ongoing COVID-19 outbreak is difficult because patients are isolated, and supplies of personal protective equipment (PPE) supplies are limited. The risk of transmission to study personal is non-negligible even when PPE is available.

A study design based on an electronic questionnaire and consent from delivered from the Oslo University Hospital/University of Oslo, GDPR (General Data Protection Regulation) compliant "TSD" service has therefore been chosen.

The study will be a case-control study based on a combined electronic consent form and questionnaire that the participants will fill in using a smartphone and electronic identification.

The groups that will be included are:

* Hospitalized and non-hospitalized patients/persons with COVID-19 at all stages of the disease and after the disease
* Hospitalized patients without COVID-19
* Healthcare personal or other groups with an increased risk of COVID-19
* Healthy volunteers

Participants may be followed with repeated questionnaires prospectively.

Biological samples Biological samples may hold crucial information about the susceptibility to COVID-19 and for susceptibility to the progression of the disease. It is within the scope of the study to analyze such samples from a limited number of participants which will be asked to provide such samples or hospitalized patients that have surplus material. The material will be analyzed with non-genetic methods most suitable to provide such information.

Eligibility criteria: Inclusion Criteria:

* Norwegian adult

Exclusion Criteria:

* Unable to consent

Primary outcomes:
measure: Rate of COVID-19 infection
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Oslo
country: Norway
facility: Oslo University Hospital
Study officials:
References: