Clinical trial NCT00718198: Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes
Official title: Effects of a Computerized Physician Order Entry (CPOE)-Based Inpatient Insulin Protocol on Glycemic Outcomes
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Diabetes Mellitus
Keywords: Inpatient
Computer Physician Order Entry
Diabetes Mellitus
Lead sponsor: Cook County Health
Sponsor class: OTHER_GOV
First posted: 2008-07-18
Enrollment: 413
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Diabetic patients admitted to Medicine Services

Brief summary: Retrospective cross-sectional study measuring the impact of a computer=based insulin correction protocol and nursing inservicing on diabetes outcomes

Detailed description: This study is a retrospective cross-sectional study at one institution, where the investigators compared diabetic patients admitted to Medicine Services from March-April 2006 (before CPOE was implemented) to patients admitted from October-November 2007 (one year after CPOE implementation). Capillary blood glucose values, Hemoglobin AIC, diabetes medication profile and demographic data were obtained to compare between groups. The investigators hypothesized that a computer-based protocol that emphasizes basal-bolus and correctional insulin orders and excludes sliding scale, in conjunction with nursing personnel inservicing, improves outcomes.

Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of Diabetes Mellitus

Exclusion Criteria:

* Admitted to Non-Medicine Hospital Services

Primary outcomes:
measure: Mean Inpatient Glucose
timeFrame: From day of admission to hospital until day of discharge from hospital
Secondary outcomes:
measure: Percentage of normoglycemic (70 to 150 mg/dl) patient-days
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Percentage of hyperglycemic patient-days
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Percentage of Patient-days with glucose less than 70 mg/dl
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Percentage of Patients with inpatient or recent (less than 6 months) hemoglobin AIC
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Length of stay
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Distribution of oral hypoglycemic use
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Distribution of type of insulin therapy used
timeFrame: From day of admission to hospital until day of discharge from hospital
measure: Percent of patient-days with severe hypoglycemia
timeFrame: From day of admission to hospital until day of discharge from hospital
Other outcomes:
Locations:
city: Chicago
country: United States
facility: John H. Stroger Jr. Hospital
state: Illinois
Study officials:
affiliation: Rush University Hospital/John H Stroger Jr. Hospital
name: Yannis S Guerra, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: John H. Stroger Jr. Hospital
name: Krishna Das, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Pete Antonopoulos, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Irene Benson, RN
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Shane Borkowski, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Leon Fogelfeld, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Melanie Gordon, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Betsy Palal, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Joana Witsil, MD
role: STUDY_CHAIR
affiliation: John H. Stroger Jr. Hospital
name: Evelyn Lacuesta, MD
role: STUDY_DIRECTOR
References: