Clinical trial NCT04201509: Validity of Neurocognitive Assessment Methods in Childhood ADHD
Official title: Validity of Neurocognitive Assessment Methods in Childhood ADHD
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Neurodevelopmental Disorders
Attention Deficit Hyperactivity Disorder
Keywords: Intelligence
Anxiety
Attention
Conduct behavior
Follow-up
Children
Lead sponsor: Region Skane
Sponsor class: OTHER
Collaborators: name: Lund University
First posted: 2019-12-17
Enrollment: 196
Sex: ALL
Minimum age (years): 7
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Children diagnosed with ADHD at the Neuropsychiatric Unit of the CAP Clinic in Lund in 2011-2012, 7 to 18 years old when recrutited to the study. School children from Lund, 7 to 18 years old when recrutited to the study.

Brief summary: The aim of the study is to examine the prospective validity of neurocognitive functions and emotional factors in schoolchildren with ADHD and a control group of typically developing schoolchildren at baseline and after three years.

Detailed description: In spite of extensive research on children with ADHD, there is still insufficient understanding of the discriminative validity of neurocognitive tests and how test results of neurocognitive functions and ratings of emotional factors and ADHD symptoms change over time and interacts during development. The project is studying the validity of clinical assessment methods within the Swedish child and adolescent psychiatry service (CAP) related to the identification of ADHD, additional impairments, and comorbidity. The prospective validity of neurocognitive functions and emotional factors in schoolchildren with ADHD and a control group of typically developing schoolchildren at baseline and after three years will be investigated.

Specific aims: Aim I: Study how attentiveness and impulsivity in ADHD change over three years by comparing the results of psychological tests and rating scales at baseline and after three years Aim II: Study intellectual development in ADHD by comparing the results of intelligence tests at baseline and after three years- Aim III: Study how emotional factors change over three years by comparing the results of rating scales at baseline and after three years

Eligibility criteria: Inclusion Criteria: The ADHD-group:

• The individuals were assessed and diagnosed with ADHD at the Neuropsychiatric Unit of the CAP Clinic in Lund in 2011-2012

Non-clinical group:

* School children from Lund.

Exclusion Criteria:

* If the individual had a diagnosed intellectual disability
* If the individual required an interpreter to participate in the study

Primary outcomes:
measure: Emotional status assessed with the Beck Youth Inventory.
timeFrame: 2011-2012 and 2014-2015
Secondary outcomes:
measure: Neuropsychological status assesses with the Conners' Continuous Performance Test (CPT) II
timeFrame: 2011-2012 and 2014-2015
Other outcomes:
measure: Cognitive status assesses with the Weschsler Intelligence Scales for Children-Fourth Edition (WISC-IV)
timeFrame: 2011-2012 and 2014-2015
Locations:
city: Lund
country: Sweden
facility: Pia Tallberg
state: Skane
Study officials:
affiliation: Lund University
name: Peik Gustafsson, Dr
role: PRINCIPAL_INVESTIGATOR
References: