Clinical trial NCT00183105: ASAP Study - Hospital-Based Brief Intervention for Alcohol Problems
Official title: Hospital-based Brief Intervention for Alcohol Problems
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Alcohol Dependence
Alcohol Consumption
Keywords: Alcohol
Alcohol abuse
Alcohol dependence
Utilization
Alcohol consumption
Unhealthy alcohol use
Hospitalization
Screening
Brief Intervention
Motivational Interviewing
Randomized trial
Effectiveness
Unhealthy alcohol use (Risky alcohol consumption amounts, problem alcohol use, hazardous alcohol use, alcohol abuse and alcohol dependence)
Lead sponsor: Boston Medical Center
Sponsor class: OTHER
Collaborators: name: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
name: University of Pittsburgh
name: Boston University
First posted: 2005-09-16
Enrollment: 350
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The objective of this project was to test whether screening and brief intervention for unhealthy alcohol use leads to improved alcohol-related outcomes (such as alcohol consumption and linkage to alcohol assistance) and is cost-effective.

Detailed description: In this study the effectiveness and cost-effectiveness of brief intervention for unhealthy alcohol use in a diverse group of hospitalized medical patients was tested.

We conducted a randomized trial of medical inpatients with the whole spectrum of alcohol problems from risky use through dependence. Subjects in one group received standard care; subjects in the second group received a brief motivational intervention tailored to the severity of his or her alcohol problem. Primary outcomes are alcohol consumption and linkage to alcohol treatment. Additional outcomes include health-related quality of life, health care utilization, alcohol problems, and readiness to change. Costs, and clinical outcomes measured in quality-adjusted life years, a standard metric that allows comparison to other chronic illnesses, will be compared in a cost-effectiveness analysis.

Eligibility criteria: Inclusion Criteria:

* 18 years of age or older
* Fluent in English or Spanish
* Consume risky amounts of alcohol
* Provide 2 contacts to assist with follow-up
* Have no plans to move from the local area within a year of screening
* Score \>21 on Mini-Mental State Examination (no serious cognitive impairment)

Primary outcomes:
measure: Linkage to alcohol assistance
measure: Change in drinks per day
Secondary outcomes:
measure: Change in the number of times a subject exceeded per occasion limits
measure: Abstinence (dichotomous)
measure: Change in drinks per day
measure: Drinking risky amounts (dichotomous)
measure: Binge drinking (dichotomous)
measure: Hospitalization
measure: Emergency Department visits
measure: Health related quality of life
measure: Readiness to change alcohol use
Other outcomes:
Locations:
city: Boston
country: United States
facility: Boston Medical Center
state: Massachusetts
Study officials:
affiliation: Boston Medical Center
name: Richard Saitz, M.D., M.P.H.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Kraemer KL, Roberts MS, Horton NJ, Palfai T, Samet JH, Freedner N, Tibbetts N, Saitz R. Health utility ratings for a spectrum of alcohol-related health states. Med Care. 2005 Jun;43(6):541-50. doi: 10.1097/01.mlr.0000163644.97251.14.
citation: Saitz R, Palfai TP, Cheng DM, Horton NJ, Freedner N, Dukes K, Kraemer KL, Roberts MS, Guerriero RT, Samet JH. Brief intervention for medical inpatients with unhealthy alcohol use: a randomized, controlled trial. Ann Intern Med. 2007 Feb 6;146(3):167-76. doi: 10.7326/0003-4819-146-3-200702060-00005.