Clinical trial NCT06509633: Effects of Pain Neuroscience Education and Standard Rehabilitation Regime in Patients of Carpal Tunnel Syndrome
Official title: Effects of Pain Neuroscience Education and Standard Rehabilitation Regime in Patients of Carpal Tunnel Syndrome
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Wrist Injuries
Carpal Tunnel Syndrome
Keywords: Carpal tunnel syndrome
Compression
Pain neuroscience education
Median nerve
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-07-19
Enrollment: 30
Sex: FEMALE
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study is to check the effects of Pain Neuroscience education and standard rehabilitation regime in patients of carpal tunnel syndrome.

Detailed description: In 2017 a stud assessed effectiveness of standard conservative protocol of CTS and nerve mobilization along with and without PNE and documented that standard conservative care seems to be the most appropriate option for pain relief, although neuroscience education might be a complementary option to accelerate recovery of function. More high-quality research is still necessary to determine its effectiveness and the subgroups of patients who may respond better to this treatment.

In 2019 a study was done to assess the effect of PNE and standard rehabilitation exercises on the 41 patients of CTS. The experimenting group was given one session of PNE plus exercises and the control group was given exercise therapy only. Patients were randomly allocated and double blinded. The analysis of study showed better results with experimental group rather than control group.

Many studies have found the effects of standard rehabilitation of Carpal Tunnel syndrome and their results in controlling pain and dysfunction. However as per researchers' knowledge little literature is available on effects of pain neuroscience education and standard rehabilitation regime in carpal tunnel syndrome. Therefore, this study6 is going to determine the effects of effectiveness of Pain Neuroscience education and standard rehabilitation regime in patients of carpal tunnel syndrome.

Eligibility criteria: Inclusion Criteria:

* age between 20_40 years old.
* Medical diagnosis of moderate to severe CTS.
* Symptoms of CTS since 1month
* Unilateral or bilateral symptoms
* Availability and access to the hospital.

Exclusion Criteria:

* Inability to understand instructions, neurological conditions of the central nervous system (e.g. stroke, spinal cord injury)
* Patients on treatment with alternative therapies
* Previous participation in a research program
* Previous surgery on the affected upper limb

Primary outcomes:
measure: Numeric pain rate scale (NPRS)
timeFrame: 4th week
Secondary outcomes:
measure: Pain Catastrophizing Scale (PCS)
timeFrame: 4th week
Other outcomes:
measure: Boston Carpal Tunnel Questionnaire (BCTQ)
timeFrame: 4th week
measure: Goniometer
timeFrame: 4th week
Locations:
city: Lahore
country: Pakistan
facility: Absaar medical center
state: Punjab
Study officials:
affiliation: Riphah International University
name: Saba khan
role: PRINCIPAL_INVESTIGATOR
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