Clinical trial NCT03621878: Effect of Neural Mobilization on Lumbosacral Radiculopathy Patients With Peripheral Sensitization
Official title: Effect of Neural Mobilization Techniques on Pain, and Hip and Knee Range of Motion on Lumbosacral Radiculopathy Patients With Peripheral Sensitization
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Radiculopathy
Keywords: Lumbosacral radiculopathy
peripheral sensitization
Neural mobilization
radicular LBP
slider
tensioner
Lead sponsor: Imam Abdulrahman Bin Faisal University
Sponsor class: OTHER
First posted: 2018-08-09
Enrollment: 51
Sex: MALE
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The primary purpose of this study was to investigate the effects of slider and tensioner techniques on pain, hip and knee ROM in lumbosacral radiculopathy patients with peripheral sensitization. A secondary purpose was to evaluate the correlation between these outcomes measurements.

Detailed description: Study design: Double-blind case-control trial. Methods: Fifty-one male lumbosacral radiculopathy patients with peripheral sensitization, were divided into one of the three groups: slider, tensioner, and control. The primary outcome measurements were visual analog scale (VAS) for pain, hip range of motion (ROM) during SLR test, and knee flexion ROM during slump test. The measurements were taken at baseline, after 1st, 3rd, and 6th session.

Statistical Analysis: A two-way mixed design analysis of variance (MANOVA) with post-hoc (Bonferonni Correction) was used to calculate the differences with Time (baseline, 1st,3rd,6th sessions) as a within-group factor and Group (control, slider, and tensioner) as a between-group factor. The effect size was calculated with Cohen's d. Pearson's correlation was used for correlation analysis.

Eligibility criteria: Inclusion Criteria:

* Patients with lumbosacral radiculopathy with dominant peripheral sensitization
* patients with unilateral leg pain.
* patient S-LANSS score \> 12,
* negative sensory and motor examination.
* positive neural tissue provocation tests (straight leg raising test, slump test).
* adult.
* pain duration of more than 3 months.

Exclusion Criteria:

* S-LANSS score ≥ 12,
* motor or sensory deficits,
* history of back or lower extremity surgeries,
* bilateral referred pain,
* patients with pacemakers, cardiovascular problems, epilepsy, active malignancy, dermatological conditions, and diminished pain sensation.

Primary outcomes:
measure: Visual Analog Scale
timeFrame: The measurements were taken at days "0,1,5,12"
measure: Hip Flexion Range of Motion (Symptomatic Side)
timeFrame: The measurements were taken at days "0,1,5,12"
measure: Knee Flexion Range of Motion (Symptomatic Side)
timeFrame: The measurements were taken at days "0,1,5,12"
measure: Hip Flexion Range of Motion (Asymptomatic Side)
timeFrame: The measurements were taken at days "0,1,5,12"
measure: Knee Flexion Range of Motion (Asymptomatic Side)
timeFrame: The measurements were taken at days "0,1,5,12"
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
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