Clinical trial NCT02596997: Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease
Official title: An Intermediate-size, Expanded Access Protocol to Provide Brincidofovir for the Treatment of Serious Adenovirus Infection or Disease
Study type: EXPANDED_ACCESS
Overall status: NO_LONGER_AVAILABLE
Conditions: Adenovirus
Keywords: Adenovirus Brincidofovir
Lead sponsor: Chimerix
Sponsor class: INDUSTRY
First posted: 2015-11-04
Sex: ALL
Minimum age (years): 2
Standard ages: CHILD
ADULT
OLDER_ADULT

Brief summary: Provide patients with serious AdV infection or disease access to treatment with BCV.


Eligibility criteria: Inclusion Criteria:

* Confirmed serious AdV infection based on clinical symptoms and laboratory testing showing AdV in the blood or other bodily fluids
* Able to swallow medication, either tablet or liquid

Exclusion Criteria:

* Previous dosing with Brincidofovir
* If female, not pregnant or trying to become pregnant

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Little Rock
country: United States
facility: University of Arkansas Medical Center
state: Arkansas
city: Los Angeles
country: United States
facility: Children's Hospital LA
state: California
city: Los Angeles
country: United States
facility: UCLA Medical Center
state: California
city: Orange
country: United States
facility: Children's Hospital of Orange County
state: California
city: Palo Alto
country: United States
facility: Pediatric Stem Cell Transplantation Stanford University
state: California
city: Palo Alto
country: United States
facility: Stanford University
state: California
city: San Diego
country: United States
facility: UC San Diego Moores Cancer center
state: California
city: San Francisco
country: United States
facility: University of California San Francisco Benioff Children's Hospital
state: California
city: Aurora
country: United States
facility: Children's Hospital Colorado
state: Colorado
city: Washington
country: United States
facility: Children's National Medical Center
state: District of Columbia
city: Gainesville
country: United States
facility: University of Florida
state: Florida
city: Saint Petersburg
country: United States
facility: All Childrens Research Institute
state: Florida
city: Saint Petersburg
country: United States
facility: All Children's Research Institute
state: Florida
city: Atlanta
country: United States
facility: Emory University-AFLAC Cancer and Blood Disorder Clinic
state: Georgia
city: Chicago
country: United States
facility: Ann & Robert H. Lurie Children's Hospital of Chicago
state: Illinois
city: Chicago
country: United States
facility: University of Chicago
state: Illinois
city: Kansas City
country: United States
facility: Children's Mercy Hospital
state: Kansas
city: Louisville
country: United States
facility: University of Louisville-Kosair Childrens Hospital
state: Kentucky
city: New Orleans
country: United States
facility: Children's Hospital New Orleans
state: Louisiana
city: Boston
country: United States
facility: Brigham & Woman's Hospital/Boston
state: Massachusetts
city: Grand Rapids
country: United States
facility: Michigan State/Spectrum Health
state: Michigan
city: Saint Louis
country: United States
facility: Washington University
state: Missouri
city: Omaha
country: United States
facility: University of Nebraska
state: Nebraska
city: Hackensack
country: United States
facility: Hackensack University MC
state: New Jersey
city: Bronx
country: United States
facility: The Children's Hospital at Montefiore
state: New York
city: New York
country: United States
facility: Weill Conrell Medical Center
state: New York
city: New York
country: United States
facility: Morgan Stanley Children's Hospital
state: New York
city: New York
country: United States
facility: Memorial Sloan Kettering
state: New York
city: New York
country: United States
facility: New York Medical College-Maria Fareri Childrens hospital
state: New York
city: Valhalla
country: United States
facility: New York Medical College, Maria Fareri Children's Hospital
state: New York
city: Charlotte
country: United States
facility: Levine Children's Hospital
state: North Carolina
city: Durham
country: United States
facility: Duke University Medical System
state: North Carolina
city: Cincinnati
country: United States
facility: Cincinnatti Children's Hospital
state: Ohio
city: Cleveland
country: United States
facility: Cleveland Clinic
state: Ohio
city: Columbus
country: United States
facility: Nationwide Children's Hospital
state: Ohio
city: Philadelphia
country: United States
facility: The Childrens hospital of Philadelphia
state: Pennsylvania
city: Memphis
country: United States
facility: Methodist University Hospital-BMT program west clinic
state: Tennessee
city: Memphis
country: United States
facility: St. Jude Research Hospital
state: Tennessee
city: Dallas
country: United States
facility: UT Southwestern Medical Center
state: Texas
city: Fort Worth
country: United States
facility: Cook Children's Health Care System
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine-Infectious Disease
state: Texas
city: Houston
country: United States
facility: University of Texas, MD Anderson Cancer Center
state: Texas
city: San Antonio
country: United States
facility: Methodist Children's Hospital of South Texas
state: Texas
city: Seattle
country: United States
facility: University of Washington/ Seattle Children's Hospital
state: Washington
city: Seattle
country: United States
facility: Fred Hutchinson Cancer Research Center
state: Washington
city: Wauwatosa
country: United States
facility: Medical College of Wisconsin
state: Wisconsin
Study officials:
References: