Clinical trial NCT06502587: Effects of Blood Flow Restriction Training With Low Intensity Exercises in Knee Osteoarthritis
Official title: Effects of Blood Flow Restriction Training With Low Intensity Exercises on Pain,Range of Motion and Quality of Life in Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Blood flow restriction training
Knee Osteoarthritis
Pain
Quality of life
Range of motion
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-07-16
Enrollment: 36
Sex: ALL
Minimum age (years): 40
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study is to examine the effects of blood flow restriction training(BFRT) with low intensity exercises on pain, range of motion and quality of life in Knee Osteoarthritis. A randomized clinical trial will be conducted at Lahore general hospital. Non-probability convenience sampling will be used, and 36 subjects, age 40-65 years will be randomly allocated into two groups by lottery method after meeting the inclusion criteria.

Detailed description: The aim of the study is to examine the effects of blood flow restriction training(BFRT) with low intensity exercises on pain, range of motion and quality of life in Knee Osteoarthritis. A randomized clinical trial will be conducted at Lahore general hospital. Non-probability convenience sampling will be used, and 36 subjects, age 40-65 years will be randomly allocated into two groups by lottery method after meeting the inclusion criteria. Both groups will receive Ultrasound therapy for 7 minutes, as common treatment. Group A will be treated with Blood flow restriction training with low intensity exercises and Group B will be treated with baseline treatment only. 3 sessions per week and total 12 sessions for 4 weeks. The outcome measures will be conducted through NPRS, Womac index for osteoarthritis,kellgren and lawrence scale and goniometry before and after 4 weeks. Data will be analyzed using SPSS software version 26.

Eligibility criteria: Inclusion Criteria:

* Both Male and Female age between 40 to 65 years diagnosed with womac ostearthritis index having acute knee pain.
* Patients with history of osteoarthritis (of grade 1 and 2 with KL(kellgren and Lawerence)) grading system for knee Osteoarthritis
* Pain in and around knee measuring through Numeric Pain rating Scale(NPRS)\>4(14)

Exclusion Criteria:Patient with history of

* hypertension
* diabetes
* sickle cell anemia
* renal compromise
* obesity
* open fracture,
* increased intracranial pressure
* pregnancy
* cancer or tumor,
* extremity with dialysis access,
* extremity fracture
* peripheral vascular compromise
* DVT(Deep vein thrombosis) \& pulmonary embolism deformity of hip \& back

Primary outcomes:
measure: NPRS Numeric pain rating scale
timeFrame: 4th week
Secondary outcomes:
measure: Womac index for knee osteoarthritis
timeFrame: 4th week
measure: Knee Related QOL (QUALITY OF LIFE) Subscale From KOOS
timeFrame: 4th week
measure: Universal goniometer
timeFrame: 4th week
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Lahore General Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Iqra Khan, Mphil
role: PRINCIPAL_INVESTIGATOR
References:
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