Clinical trial NCT04228887: Effects of Inspiratory Muscle Training in Patients With Parkinson's Disease
Official title: Effects of Inspiratory Muscle Training on Postural Stability, Mobility, Activities of Daily Living, Quality of Life and Respiratory Function in Patients With Parkinson's Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease
Keywords: Parkinson's Disease
Inspiratory Muscle Training
Balance Training
Lead sponsor: Bezmialem Vakif University
Sponsor class: OTHER
First posted: 2020-01-14
Enrollment: 30
Sex: ALL
Minimum age (years): 60
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: In this study investigators will examine the effects of inspiratory muscle training and balance training in patients with Parkinson's Disease

Detailed description: Parkinson's Disease (PD) is the most common type of Parkinsonism and mainly due to degeneration of basal ganglions and substantia nigra occurs. Balance disorders are one of the common problems in patients with Parkinson's disease. These balance disorders; loss of postural reflexes, insufficiency in postural adjustments, rigidity in the trunk and extremities, and many disorders such as akinesia. Because of balance disorders in patients with PD, increase in addiction to daily life activities, causes physical disability. In the case of PD pulmonary problems may be the leading cause of mortality and mortality. Respiratory symptoms in these patients cause problems in weakness, swallowing, coughing, voice and speech functions. When the investigators look at the current literature, the effect of balance and respiration on Parkinson's patients is found to be seperately but their effect on each other is not sufficiently emphasized. For this reason, the researchers' aim to investigate balance and postural control in patients with Parkinson's disease and to increase the strength of respiratory muscles and to improve balance and postural control.

Eligibility criteria: Inclusion Criteria:

* Diagnosed with Parkinson'S Disease
* Ages between 60 and 85 years
* Grades 1 to 3 according to Modified Hoehn-Yahr Scale

Exclusion Criteria:

* Lung surgery or diagnosed lung disease history
* Dementia
* Having a orthopedic disorder which may affect balance and/or mobility
* Severe dyskinesia and cognition problems

Primary outcomes:
measure: Inspiratory Muscle Strength
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Respiratory Function- Forced Vital Capasity (FVC)
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Respiratory Function- Forced Expiratory Volume in 1 second
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Respiratory Function- Peak Expiratory Flow
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Postural Control and Balance
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Parkinson's Status- Unified Parkinson's Disease Rating Scale
timeFrame: Change from baselines to final evaluation at 8th weeks
Secondary outcomes:
measure: Mobility Status- Rivermead mobility index
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Quality of Life Parameter-Nottingham Health Profile
timeFrame: Change from baselines to final evaluation at 8th weeks
measure: Activities of Daily Living-Barthel
timeFrame: Change from baselines to final evaluation at 8th weeks
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakif University
Study officials:
affiliation: Bezmialem Vakif University
name: Hülya N Gürses, Prof
role: STUDY_DIRECTOR
References: