Clinical trial NCT05211947: A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study
Official title: An Open Label, Single Arm, Extension Trial to Examine Long-term Safety of Iclepertin Once Daily in Patients With Schizophrenia Who Have Completed Previous Iclepertin Phase III Trials (CONNEX-X)
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: PHASE3
Conditions: Schizophrenia
Lead sponsor: Boehringer Ingelheim
Sponsor class: INDUSTRY
First posted: 2022-01-27
Enrollment: 1362
Sex: ALL
Minimum age (years): 18
Maximum age (years): 51
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study is open to adults with schizophrenia who took part in a previous CONNEX study (study 1346-0011, 1346-0012, or 1346-0013). The purpose of this study is to find out how well people with schizophrenia can tolerate a medicine called Iclepertin in the long term.

Participants take Iclepertin as tablets once a day for 1 year. In addition, all participants take their normal medication for schizophrenia.

Participants are in the study for a little more than 1 year. During this time, they visit the study site about 13 times and get about 9 phone calls from the study team.

The doctors collect information on any health problems of the participants. Doctors also regularly check the participants' symptoms of schizophrenia.


Eligibility criteria: Inclusion criteria:

* Signed and dated written informed consent.
* Clinically stable outpatients who have been diagnosed with schizophrenia (as per Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5)).
* Patients, who completed participation in the parent trial.
* Women of childbearing potential must use highly effective methods of birth control.
* Have a study partner who interacts with the patient on a regular basis. Further inclusion criteria apply.

Exclusion criteria:

* Participant who developed DSM-5 diagnosis other than Schizophrenia or any condition that would prevent the patient from participating in the extension trial since enrolment into the parent phase III trial.
* Any suicidal behavior and/or suicidal ideation of type 5 based on the Columbia Suicidality Severity Rating Scale (C-SSRS) in parent trial and up to and including Visit 1 of this study.
* Positive urine drug screen ≥ 3 times during the treatment period of parent trial.
* Patients who are currently or wish to participate in another investigational drug trial.
* Any clinically significant finding or condition in the judgment of the investigator that would jeopardize the patient´s safety while participating in the trial or their capability to participate in the trial.

Further exclusion criteria apply.

Primary outcomes:
measure: Occurrence of treatment emergent adverse events (TEAEs)
timeFrame: up to 1 year and 12 days
Secondary outcomes:
measure: Change from baseline in Clinical Global Impressions - Severity (CGI-S) to end of treatment (EOT)
timeFrame: up to 1 year
measure: Change from baseline in Haemoglobin (Hb) to EOT
timeFrame: up to 1 year
Other outcomes:
Locations:
city: Anaheim
country: United States
facility: Advanced Research Center, Inc.
state: California
city: Bellflower
country: United States
facility: Clinical Innovations, Inc
state: California
city: Culver City
country: United States
facility: ProScience Research Group
state: California
city: Garden Grove
country: United States
facility: Collaborative Neuroscience Network, LLC (CNS)
state: California
city: La Habra
country: United States
facility: Omega Clinical Trials,LLC
state: California
city: Long Beach
country: United States
facility: ASCLEPES Research Centers, P.C. dba Alliance Research
state: California
city: Los Angeles
country: United States
facility: University of California Los Angeles
state: California
city: Orange
country: United States
facility: ATP Clinical Research, Inc.
state: California
city: Orange
country: United States
facility: NRC Research Institute
state: California
city: Pico Rivera
country: United States
facility: CNRI - Los Angeles
state: California
city: San Diego
country: United States
facility: Artemis Institute for Clinical Research, LLC
state: California
city: Santa Ana
country: United States
facility: Velocity Clinical Research-Santa Ana-68902
state: California
city: Stanford
country: United States
facility: Stanford University Medical Center
state: California
city: Torrance
country: United States
facility: Collaborative Neuroscience Research
state: California
city: Hartford
country: United States
facility: Institute of Living
state: Connecticut
city: New Haven
country: United States
facility: Connecticut Mental Health Center
state: Connecticut
city: Hollywood
country: United States
facility: Advanced Medical Research Group Inc
state: Florida
city: Maitland
country: United States
facility: Accel Research Sites Network
state: Florida
city: Miami
country: United States
facility: San Marcus Research Clinic, Inc.
state: Florida
city: Miami
country: United States
facility: CCM Clinical Research Group, LLC-Miami-68482
state: Florida
city: Miami
country: United States
facility: Optimus U Corporation-Miami-69452
state: Florida
city: Miami
country: United States
facility: University of Miami
state: Florida
city: Orlando
country: United States
facility: Nova Psychiatry Inc.
state: Florida
city: Atlanta
country: United States
facility: Synexus Clinical Research-Atlanta-67262
state: Georgia
city: Chicago
country: United States
facility: American Medical Research
state: Illinois
city: Baltimore
country: United States
facility: Sheppard Pratt Physicians's Practice Association, Inc.
state: Maryland
city: Gaithersburg
country: United States
facility: Center for Behavioral Health, LLC
state: Maryland
city: Saint Louis
country: United States
facility: PsychCare Consultants Research
state: Missouri
city: Saint Louis
country: United States
facility: Arch Clinical Trials, LLC
state: Missouri
city: Omaha
country: United States
facility: Omaha Insomnia and Psychiatric Services
state: Nebraska
city: Marlton
country: United States
facility: Hassman Research Institute-Marlton-66897
state: New Jersey
city: Cedarhurst
country: United States
facility: Neurobehavioral Research, Inc.
state: New York
city: New York
country: United States
facility: New York State Psychiatric Institute
state: New York
city: Staten Island
country: United States
facility: Richmond Behavioral Associates-Staten Island-68636
state: New York
city: Raleigh
country: United States
facility: UNC Center for Excellence in Community Mental Health, North Carolina Psychiatric Research Center
state: North Carolina
city: Cincinnati
country: United States
facility: University of Cincinnati
state: Ohio
city: Dayton
country: United States
facility: Midwest Clinical Research
state: Ohio
city: Independence
country: United States
facility: Insight Clinical Trials, LLC, Independence
state: Ohio
city: Oklahoma City
country: United States
facility: SP Research, PLLC
state: Oklahoma
city: Eugene
country: United States
facility: University of Oregon Prevention Science Institute
state: Oregon
city: State College
country: United States
facility: Oasis Life Care
state: Pennsylvania
city: Austin
country: United States
facility: Community Clinical Research, Inc.
state: Texas
city: Dallas
country: United States
facility: Relaro Medical Trials, LLC
state: Texas
city: DeSoto
country: United States
facility: InSite Clinical Research
state: Texas
city: Fort Worth
country: United States
facility: JPS Center for Behavioral Health Recovery
state: Texas
city: Fort Worth
country: United States
facility: North Texas Clinical Trials
state: Texas
city: Houston
country: United States
facility: Ben Taub General Hospital
state: Texas
city: Richmond
country: United States
facility: LinQ Research, LLC-Richmond-70076
state: Texas
city: Bellevue
country: United States
facility: Northwest Clinical Research Center
state: Washington
city: Banfield
country: Argentina
facility: Clínica Privada Banfield
city: Caba
country: Argentina
facility: CENYDET-Centro Neurobiologico y de Estres Traumatico (Biopsychomedical Research Group S.R.L.)
city: Caba
country: Argentina
facility: Fundación para el Estudio y Tratamiento de las Enfermedades Mentales (FETEM)
city: Caba
country: Argentina
facility: Fundación FunDaMos para la asistencia e investigación en psiquiatría
city: Cordoba
country: Argentina
facility: CEN (Centro Especializado Neurociencias)
city: Cordoba
country: Argentina
facility: Instituto Médico DAMIC S.R.L.
city: Córdoba
country: Argentina
facility: Instituto Modelo de Neurología Lennox
city: Córdoba
country: Argentina
facility: Sanatorio Morra S.A.
city: La Plata
country: Argentina
facility: Instituto de Neurociencias San Agustín
city: La Plata
country: Argentina
facility: Global Psy Asociación Civil
city: Mendoza
country: Argentina
facility: Resolution Psychopharmacology Research Institute
city: Rosario
country: Argentina
facility: Instituto Médico de la Fundación Estudios Clínicos
city: Rosario
country: Argentina
facility: Centro de Investigacion y Asistencia en Psiquiatria (CIAP)
city: San Vicente
country: Argentina
facility: Centro Medico Luquez
city: Melbourne
country: Australia
facility: Monash Alfred Psychiatry Research Centre
state: Victoria
city: Vienna
country: Austria
facility: AKH - Medical University of Vienna
city: Bertix
country: Belgium
facility: CUP Vivalia -La Clairière
city: Bierbeek
country: Belgium
facility: Sint-Kamillus
city: Duffel
country: Belgium
facility: Universitair Psychiatrisch Centrum Duffel (UPC Duffel)
city: Mechelen
country: Belgium
facility: Meclinas
city: Belo Horizonte
country: Brazil
facility: CPN - Centro de Estudos em Neurociências
city: Criciuma
country: Brazil
facility: Hospital Sao Jose
city: Curitiba
country: Brazil
facility: Trial Tech- Tecnologia em pesquisa com medicamentos
city: Goiania
country: Brazil
facility: J A Serviços Médicos Ltda/ Instituto Goiano de Neuropisquiatria
city: Rio de Janeiro
country: Brazil
facility: Ruschel Medicina e Pesquisa Clínica
city: Sao Jose do Rio Preto
country: Brazil
facility: Hospital de Base - Fac Med de Sao Jose do Rio Preto
city: Sao Paulo
country: Brazil
facility: BR Trials
city: Sao Paulo
country: Brazil
facility: Clínica Viver - Centro de Desospitalização Humana
city: São Bernardo do Campo
country: Brazil
facility: CEMEC - Centro Multidisciplinar de Estudos Clínicos
city: São Paulo
country: Brazil
facility: Cpquali Pesquisa Clinica Ltda
city: São Paulo
country: Brazil
facility: Hospital das Clinicas da FMUSP
city: Plovdiv
country: Bulgaria
facility: Medical Center "Spectar"
city: Plovdiv
country: Bulgaria
facility: Filipopolis Ambulatory for Group Practice for Specialized Care in Psychiatry
city: Calgary
country: Canada
facility: University of Calgary
state: Alberta
city: Toronto
country: Canada
facility: Centre for Addiction and Mental Health (CAMH)
state: Ontario
city: Santiago
country: Chile
facility: Biomedica Research Group
city: Segunda Región
country: Chile
facility: Psicomed Estudios Clínicos
city: Baoding
country: China
facility: The sixth People's Hospital of Hebei Province
city: Beijing
country: China
facility: Beijing Anding Hospital
city: Beijing
country: China
facility: Peking University Sixth Hospital
city: Beijing
country: China
facility: Beijing HuiLongGuan Hospital
city: Changsha
country: China
facility: The Second People's Hospital of Hunan Province (Brain Hospital of Hunan Province)
city: Changsha
country: China
facility: The Second Xiangya Hospital Of Central South University
city: Guangzhou
country: China
facility: The Affiliated Brain Hospital of Guangzhou Medical University
city: Guangzhou
country: China
facility: The third affiliated hospital of Sun Yat-Sen University
city: Huzhou
country: China
facility: Huzhou Third Municipal Hospital
city: Jining
country: China
facility: Shandong Daizhuang Hospital
city: Kunming
country: China
facility: The First Affilliated Hospital Of Kunming of Medical College
city: Nanjing
country: China
facility: Nanjing Brain Hospital
city: Ningbo
country: China
facility: The Affilicated Kangning Hospital of Ningbo University
city: Shanghai
country: China
facility: Shanghai Mental Health Center
city: Shanghai
country: China
facility: Tongji Hospital, Tongji University
city: Shenzhen
country: China
facility: Shenzhen Kangning Hospital
city: Shijiazhuang
country: China
facility: The First Hospital of Hebei Medical University
city: Tianjin
country: China
facility: Tianjin Anding Hospital
city: Wuxi
country: China
facility: Wuxi mental health center
city: Xi'an
country: China
facility: First Affiliated Hospital of Xi'an JiaoTong University
city: Xi'an
country: China
facility: Xi'an Mental Health Center
city: Xinxiang
country: China
facility: The Second Affiliated Hospital of Xinxiang Medical Univ.
city: Zhumadian
country: China
facility: Zhumadian Psychiatric Hospital
city: Barranquilla
country: Colombia
facility: Centro de Investigación y Proyectos en neurociencia CIPNA
city: Bello
country: Colombia
facility: E.S.E Hospital Mental de Antioquia
city: Bogota
country: Colombia
facility: Instituto Colombiano del Sistema Nervioso- Clínica Montserrat
city: Bogotá
country: Colombia
facility: Centro de Investigaciones del Sistema Nervioso SAS- Grupo Cisne SAS
city: Pereira
country: Colombia
facility: Psynapsis Salud Mental S.A.
city: Rijeka
country: Croatia
facility: Clincal Hospital Centre Rijeka
city: Zagreb
country: Croatia
facility: Clinical Hospital Centre Zagreb
city: Zagreb
country: Croatia
facility: Solmed Polyclinic
city: Zagreb
country: Croatia
facility: Psychiatric Hospital 'Sveti Ivan'
city: Zagreb
country: Croatia
facility: University Psychiatric Hospital Vrapce
city: Klecany
country: Czechia
facility: National Institute of Mental Health
city: Ostrava
country: Czechia
facility: MP Meditrine s.r.o.
city: Plzen
country: Czechia
facility: A-SHINE s.r.o
city: Prague
country: Czechia
facility: PRAGTIS s.r.o.
city: Prague
country: Czechia
facility: INEP medical s.r.o.
city: Ricany
country: Czechia
facility: Psychiatrie Ricany s.r.o.
city: Aalborg
country: Denmark
facility: Aalborg Universitetsshospital
city: Aarhus N
country: Denmark
facility: Aarhus University Hospital
city: Glostrup
country: Denmark
facility: Psykiatrisk Center Glostrup
city: Helsinki
country: Finland
facility: Aurora hospital
city: Turku
country: Finland
facility: CRST - Clinical Research Services Turku
city: Bordeaux
country: France
facility: HOP Charles Perrens
city: Montpellier
country: France
facility: HOP la Colombière
city: Nantes
country: France
facility: HOP Hôtel-Dieu
city: Nice
country: France
facility: HOP Pasteur
city: Nîmes
country: France
facility: HOP Carémeau
city: Rennes
country: France
facility: HOP Guillaume Régnier
city: Rouffach
country: France
facility: HOP Rouffach
city: Saint Priest en Jarez
country: France
facility: HOP Nord-Saint-Priest-en-Jarez-53664
city: Bad Homburg
country: Germany
facility: Zentrum für klinische Forschung Dr. med. I. Schöll GmbH
city: Berlin
country: Germany
facility: Praxis Dr. Hahn, Berlin
city: Böblingen
country: Germany
facility: Studienzentrum für Neurologie und Psychiatrie
city: Dortmund
country: Germany
facility: LWL-Klinik Dortmund
city: Mainz
country: Germany
facility: Universitätsmedizin der Johannes Gutenberg-Universität Mainz
city: Mannheim
country: Germany
facility: Zentralinstitut für seelische Gesundheit
city: München
country: Germany
facility: Klinikum der Universität München AÖR
city: Tübingen
country: Germany
facility: Universitätsklinikum Tübingen
city: Westerstede
country: Germany
facility: Studienzentrum Nord-West
city: Athens
country: Greece
facility: Eginition Hospital
city: Chaidari
country: Greece
facility: Attikon University General Hospital of Attica
city: Haidari
country: Greece
facility: Psychiatric Hospital of Attica
city: Heraclion
country: Greece
facility: AX Mental Health Clinic
city: Nea Kifisia
country: Greece
facility: General Oncology Hospital "Agioi Anargyri"
city: Thessaloniki
country: Greece
facility: University General Hospital of Thessaloniki AHEPA
city: Thessaloniki
country: Greece
facility: General Hospital of Thessaloniki "G. Papanikolaou"
city: Budapest
country: Hungary
facility: Semmelweis University
city: Brescia
country: Italy
facility: ASST degli Spedali Civili di Brescia
city: Milano
country: Italy
facility: A.O. Fatebenefratelli
city: Milano
country: Italy
facility: Ist. San Raffaele Turro
city: Orbassano (to)
country: Italy
facility: Azienda Sanitaria Ospedale S. Luigi Gonzaga
city: Siena
country: Italy
facility: A.O.U. Senese Policlinico Santa Maria alle Scotte
city: Aichi, Konan
country: Japan
facility: Hotei Hospital
city: Aichi, Toyoake
country: Japan
facility: Okehazama Hospital Fujita Kokoro Care Center
city: Aichi, Toyota
country: Japan
facility: Toyota Memorial Hospital
city: Chiba, Chiba
country: Japan
facility: National Hospital Organization Shimofusa Psychiatric Medical Center
city: Chiba, Ichikawa
country: Japan
facility: National Center for Global Health and Medicine Kohnodai Hospital
city: Fukuoka, Chikugo
country: Japan
facility: Uematsu Mental Clinic
city: Fukuoka, Fukuoka
country: Japan
facility: Mental Clinic Sakurazaka
city: Fukuoka, Fukuoka
country: Japan
facility: AK Clinic
city: Fukuoka, Fukuoka
country: Japan
facility: Fukuoka University Hospital
city: Fukuoka, Fukuoka
country: Japan
facility: Kuramitsu Hospital
city: Fukuoka, Kurume
country: Japan
facility: Hirota Clinic
city: Fukuoka, Omuta
country: Japan
facility: Shiranui Hospital
city: Gumma, Kiryu
country: Japan
facility: Kishi Hospital
city: Hokkaido, Obihiro
country: Japan
facility: Obihiro-Kosei General Hospital
city: Hokkaido, Sapporo
country: Japan
facility: Hokudai-dori Mental Health Clinic
city: Hokkaido, Sapporo
country: Japan
facility: Hokkaido University Hospital
city: Hyogo, Kobe
country: Japan
facility: Tatsuta Clinic
city: Ishikwa, Kahoku-gun
country: Japan
facility: Kanazawa Medical University Hospital
city: Kanagawa, Kawasaki
country: Japan
facility: Kishiro Mental Clinic
city: Kanagawa, Kawasaki
country: Japan
facility: St. Marianna University Hospital
city: Kanagawa, Yokohama
country: Japan
facility: Links Mental Clinic
city: Kanagawa, Yokohama
country: Japan
facility: Yokohama Onoecho Clinic
city: Kanagawa, Yokohama
country: Japan
facility: Hino Hospital
city: Kanagawa, Yokohama
country: Japan
facility: Yokohama City University Hospital
city: Kochi, Kochi
country: Japan
facility: Kochi Health Sciences Center
city: Kumamoto, Kumamoto
country: Japan
facility: Yuge Neuropsychiatric Hospital
city: Kumamoto, Yatsushiro
country: Japan
facility: Medical Corporation Yamadakai Yatsushiro Welfare Hospital
city: Kyoto, Maizuru
country: Japan
facility: National Hospital Organization Maizuru Medical Center
city: Miyagi, Sendai
country: Japan
facility: Tohoku University Hospital
city: Nagano, Matsumoto
country: Japan
facility: Shounan Hospital
city: Nagano, Suwa
country: Japan
facility: Suwa Red Cross Hospital
city: Nara, Kashihara
country: Japan
facility: Nara Medical University Hospital
city: Niigata, Niigata
country: Japan
facility: Niigata University Medical and Dental Hospital
city: Okinawa, Ginowan
country: Japan
facility: University of the Ryukyus Hospital
city: Osaka, Osaka
country: Japan
facility: Osaka City Hospital Organization Osaka City General Hospital
city: Saga, Kanzaki-gun
country: Japan
facility: National Hospital Organization Hizen Psychiatric Medical Center
city: Saga, Karatsu
country: Japan
facility: Rainbow and Sea Hospital
city: Saga, Tosu
country: Japan
facility: Inuo Hospital
city: Saitama, Kumagaya
country: Japan
facility: Nishi Kumagaya Hospital
city: Saitama, Saitama
country: Japan
facility: Sho Midori Hospital
city: Tochigi, Shimotsuga-gun
country: Japan
facility: Dokkyo Medical University Hospital
city: Tokushima, Tokushima
country: Japan
facility: Tokushima University Hospital
city: Tokyo, Adachi-ku
country: Japan
facility: Medical Corporation Seijin Hospital
city: Tokyo, Bunkyo-ku
country: Japan
facility: Institute of Science Tokyo Hospital
city: Tokyo, Kita-ku
country: Japan
facility: Nishigahara Hospital
city: Tokyo, Kodaira
country: Japan
facility: National Center of Neurology and Psychiatry
city: Tokyo, Machida
country: Japan
facility: Asuka Hospital
city: Tokyo, Minato-ku
country: Japan
facility: Minami-Aoyama Antique Street Clinic
city: Tokyo, Ota-ku
country: Japan
facility: Toho University Omori Medical Center
city: Tokyo, Shibuya-ku
country: Japan
facility: Maynds Tower Mental Clinic
city: Tokyo, Shinjuku-ku
country: Japan
facility: Shinjuku East Mental Clinic
city: Tokyo, Toshima-ku
country: Japan
facility: Ohwa Mental Clinic
city: Toyama, Nanto
country: Japan
facility: Hokuriku Hospital
city: Yamaguchi, Ube
country: Japan
facility: Yamaguchi University Hospital
city: Yamanashi, Chuo
country: Japan
facility: University of Yamanashi Hospital
city: Busan
country: Korea, Republic of
facility: Inje University Busan Paik Hospital
city: Daegu
country: Korea, Republic of
facility: Yeungnam University Medical Center
city: Daegu
country: Korea, Republic of
facility: Daegu Catholic University Medical Center
city: Gwangju
country: Korea, Republic of
facility: Chonnam National University Hospital
city: Incheon
country: Korea, Republic of
facility: Inha University Hospital
city: Seongnam
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
city: Yangsan
country: Korea, Republic of
facility: Pusan National University Yangsan Hospital
city: Kaunas
country: Lithuania
facility: JSC Romuvos Clinic
city: Kaunas
country: Lithuania
facility: LUHS KH Psichiatric Clinic Mariu Division
city: Silute
country: Lithuania
facility: JSC Medical center "Puriena"
city: Vilnius
country: Lithuania
facility: Vilnius City Mental Health Center
city: Ipoh, Perak
country: Malaysia
facility: Hospital Raja Permaisuri Bainun
city: Kuala Lumpur
country: Malaysia
facility: University of Malaya Medical Centre
city: Kuching
country: Malaysia
facility: Hospital Sentosa
city: Seremban
country: Malaysia
facility: Hospital Tuanku Ja'afar
city: Cdmx
country: Mexico
facility: GabiPros S.C.
city: Ciudad de Mexico
country: Mexico
facility: Instituto Nacional de Neurologia y Neurocirugia
city: Ciudad de Mexico
country: Mexico
facility: Centro de Investigación Clinica Acelerada, S.C.
city: Culiacan
country: Mexico
facility: Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada S.C.
city: Guadalajara
country: Mexico
facility: Clinica Cemelli
city: Leon
country: Mexico
facility: Hospital Aranda de la Parra
city: Merida
country: Mexico
facility: Medical Care & Research SA de CV
city: Monterrey
country: Mexico
facility: Iecsi S.C.
city: Monterrey
country: Mexico
facility: CIT-Neuropsique S.C
city: Monterrey
country: Mexico
facility: Instituto de Informacion e Investigacion en Salud Mental A.C. (INFOSAME).
city: Nuevo León
country: Mexico
facility: Hospital Universitario Dr Jose Eleuterio Gonzalez
city: San Luis Potosi
country: Mexico
facility: BIND Investigaciones S.C.
city: Groningen
country: Netherlands
facility: Universitair Medisch Centrum Groningen
city: Takpuna Auckland
country: New Zealand
facility: North Shore Hospital
city: Moss
country: Norway
facility: Sykehuset Østfold HF, avd. Moss
city: Oslo
country: Norway
facility: Akershus universitetssykehus Oslo
city: Manila, Philippines
country: Philippines
facility: Philippine General Hospital
city: Bełchatow
country: Poland
facility: Psychiatric Doctor's Office Ireneusz Kaczorowski
city: Bialystok
country: Poland
facility: Podlassian Center of Psychogeriatry, Bialystok
city: Gdansk
country: Poland
facility: Health Center Alcea
city: Gliwice
country: Poland
facility: MentalMEDIC
city: Lodz
country: Poland
facility: Central Teaching Hospital of the Medical University of Lodz
city: Poznan
country: Poland
facility: Individual Specialist Medical Practice Filip Rybakowski
city: Szczecin
country: Poland
facility: EUROMEDIS Sp. z o.o., Szczecin
city: Warsaw
country: Poland
facility: Institute of Psychiatry and Neurology in Warsaw
city: Zabrze
country: Poland
facility: Clinhouse
city: Leiria
country: Portugal
facility: ULS da Região de Leiria, E.P.E.
city: Bucharest
country: Romania
facility: Mental Health Center Sector 4
city: Sibiu
country: Romania
facility: SC Carpe Diem SRL
city: Belgrade
country: Serbia
facility: Clinical Hospital Center Dr. Dragisa Misovic
city: Belgrade
country: Serbia
facility: General Hospital Euromedik
city: Belgrade
country: Serbia
facility: Institute for Mental Health
city: Gornja Toponica
country: Serbia
facility: Special Hospital for Psychiatric Diseases Gornja Toponica
city: Novi Knezevac
country: Serbia
facility: Special Hospital for Psychiatric Diseases Sveti Vračevi
city: Novi Sad
country: Serbia
facility: Clinical Center of Vojvodina
city: Bojnice
country: Slovakia
facility: Psychiatria, Nemocnica s poliklinikou Prievidza so sidlom v Bojniciach
city: Kosice
country: Slovakia
facility: EPAMED s.r.o.
city: Rimavska Sobota
country: Slovakia
facility: Psychiatricka Ambulancia Psycholine s.r.o.
city: Barcelona
country: Spain
facility: Hestia Palau
city: Barcelona
country: Spain
facility: Hospital Clínic de Barcelona
city: Collado De Villalba
country: Spain
facility: Hospital Universitario General de Villalba
city: Córdoba
country: Spain
facility: Hospital Universitario Reina Sofía-Córdoba-40500
city: Majadahonda
country: Spain
facility: Hospital Puerta de Hierro
city: Salamanca
country: Spain
facility: Centro de Salud de San Juan
city: Sevilla
country: Spain
facility: Hospital Virgen del Rocío
city: Valencia
country: Spain
facility: Hospital Clínico de Valencia
city: Vigo
country: Spain
facility: Hospital Nicolás Peña
city: Zamora
country: Spain
facility: Hospital Provincial. Complejo Asistencial de Zamora
city: Helsingborg
country: Sweden
facility: Psykiatriska Kliniken
city: Uppsala
country: Sweden
facility: Akademiska sjukhuset
city: Kaohsiung
country: Taiwan
facility: Kai-Syuan Psychiatric Hospital
city: Keelung
country: Taiwan
facility: Chang Gung Memorial Hospital Keelung
city: Taichung
country: Taiwan
facility: Chung Shan Medical University Hospital
city: Tainan
country: Taiwan
facility: NCKUH
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital
city: Taipei
country: Taiwan
facility: Taipei Veterans General Hospital
city: Taoyuan
country: Taiwan
facility: Taoyuan Psychiatric Center
city: Taoyuan
country: Taiwan
facility: Chang Gung Memorial Hospital(Linkou)
city: Ankara
country: Turkey
facility: Hacettepe Universitesi Tip Fakultesi
city: Ankara
country: Turkey
facility: Ankara University Medical School
city: Istanbul
country: Turkey
facility: Istanbul University
city: Izmir
country: Turkey
facility: Dokuz Eylul Universitesi Psikiyatri A.B.D.
city: Manisa
country: Turkey
facility: Celal Bayar Universitesi Tip Fakultesi
city: Nove
country: Ukraine
facility: Communal Non-Profit Enterprise "Regional Clinical Psychiatric Hospital" of Kirovohrad Regional Council
city: Bodmin
country: United Kingdom
facility: Bodmin Community Hospital
city: Cheltenham
country: United Kingdom
facility: The Fritchie Centre
city: Chester
country: United Kingdom
facility: Redesmere
city: Edinburgh
country: United Kingdom
facility: Western General Hospital
city: Glasgow
country: United Kingdom
facility: Queen Elizabeth University Hospital
city: London
country: United Kingdom
facility: Maudsley Hospital
city: Oxford
country: United Kingdom
facility: Warneford Hospital
city: Southampton
country: United Kingdom
facility: Moorgreen Hospital
Study officials:
References: