Clinical trial NCT00629954: Abuja Heart Study: Prospective Epidemiological Investigation of Cardiovascular Diseases
Official title: Abuja Heart Study (AHS) is a Multi-site Prospective Epidemiological Investigation of Cardiovascular Disease (CVD) .
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Cardiovascular Diseases
High Blood Pressure
Keywords: ABUJA HEART STUDY NIGERIA
CARDIOVASCULAR DISEASES
Lead sponsor: Healthsystem Plus
Sponsor class: OTHER
Collaborators: name: Federal Ministry of Health, Nigeria
name: Akaza Research
name: Byrne Healthcare
name: Baim Institute for Clinical Research
First posted: 2008-03-06
Enrollment: 10000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Abuja residents from the rural and metropolitan area.

Brief summary: This is a multi-site prospective epidemiological investigation of cardiovascular disease (CVD) among Abuja residents from the rural and metropolitan area.

Detailed description: Sub-Saharan Africa continues to fight the battle of infectious diseases such as HIV/AIDS, Tuberculosis and Malaria. But given all the international efforts geared to curing and containing these diseases, and with progress made in various countries, Sub-Saharan Africa is now heading into another type of epidemic, cardiovascular disease (CVD). Predicted statistics have shown that cardiovascular diseases will become the leading cause of death in developing countries within the next 10 to 15 years, however relatively few population-based studies have examined CVD in Africa .

Although control of communicable ,childhood ,and maternal diseases has benefited from an international efforts on clinical care, policy and implementation,such large scale effort are lacking for CVD and have left both policymakers and individuals with decisions on health issues without adequate information.

Prior to the commencement of the study,series of community meetings and focus groups discussions will be held to identify ways to enhance participation. An extensive examination will include a series of questionnaires dealing with lifestyle habits, medical history, social and cultural factors, physical assessments which include height, weight,central blood pressure assessment of arterial stiffness and autonomic function and laboratory measurements for cholesterol, other lipids, glucose ,c-reactive protein among others.

Eligibility criteria: Inclusion Criteria:

* Some history of cardiovascular disease,PLWHA
* Patients have to agree to participate by signing a consent
* 18 years and older

Exclusion Criteria:

* Stroke

Primary outcomes:
measure: determine the roles of sociocultural factors, such as poverty,gender, literacy, stress in the development of CVD and associated risk factors
timeFrame: 5
Secondary outcomes:
measure: familial or hereditary factors
timeFrame: 10
Other outcomes:
Locations:
city: Abuja
country: Nigeria
facility: National Hospital Abuja
state: Federal Capital Territory
city: Abuja
country: Nigeria
facility: State House Medical Center
state: Federal Capital Territory
city: Bwari
country: Nigeria
facility: Bwari General Hospital
state: Federal Capital Territory
city: Abuja
country: Nigeria
facility: Nigerian Defense Medical Center
city: Federal Capital Territory
country: Nigeria
facility: Gwagwalada Specialist Hospital
Study officials:
affiliation: Healthsystem Plus
name: Uchenna N Onyeachom
role: PRINCIPAL_INVESTIGATOR
affiliation: Abuja Heart Study
name: Ngozi A Njepuome
role: PRINCIPAL_INVESTIGATOR
affiliation: National Hospital, Abuja
name: Chimele Abengowe
role: STUDY_CHAIR
References: