Clinical trial NCT04323761: Expanded Access Treatment Protocol: Remdesivir (RDV; GS-5734) for the Treatment of SARS-CoV2 (CoV) Infection (COVID-19)
Official title: Expanded Access Treatment Protocol: Remdesivir (RDV; GS-5734) for the Treatment of SARS-CoV2 (CoV) Infection
Study type: EXPANDED_ACCESS
Overall status: APPROVED_FOR_MARKETING
Conditions: SARS-CoV2 Infection
Lead sponsor: Gilead Sciences
Sponsor class: INDUSTRY
First posted: 2020-03-27
Sex: ALL
Minimum age (years): 12
Standard ages: CHILD
ADULT
OLDER_ADULT

Brief summary: The primary objective of this study is to provide expanded access of remdesivir (RDV) for the treatment of severe acute respiratory syndrome coronavirus (SARS-CoV2) infection.


Eligibility criteria: Inclusion Criteria:

* Willing and able to provide written informed consent, or with a legal representative who can provide informed consent, or enrolled under International Conference on Harmonization (ICH) E6(R2) 4.8.15 emergency use provisions as deemed necessary by the investigator (participants ≥ 18 years of age), or willing and able to provide assent (participants ≥ 12 and \< 18 years of age, where locally and nationally approved) prior to performing study procedures. For participants ≥ 12 and \< 18 years of age, a parent or legal guardian willing and able to provide written informed consent prior to performing study procedures.
* Age ≥ 18 years or aged ≥ 12 and \< 18 years of age weighing ≥ 40 kg (where permitted according to local law and approved nationally and by the relevant institutional review board (IRB) or independent ethics committee (IEC))
* Hospitalized with confirmed SARS-CoV2 by polymerase chain reaction (PCR) or known contact of confirmed case with syndrome consistent with coronavirus disease (COVID-19) with PCR pending
* Oxygen saturation (SpO2) ≤ 94% on room air or requiring supplemental oxygen at baseline
* Alanine aminotransferase (ALT) \< 5 x upper limit of normal (ULN) by local laboratory measure and/or ALT \< 3 x ULN and bilirubin \< 2 x ULN
* Females of childbearing potential who engage in heterosexual intercourse must agree to use protocol specified method(s) of contraception
* Lactating females must agree to discontinue nursing before the study drug is administered and while they are participating in the study

Exclusion Criteria:

* Evidence of multiorgan failure including but not limited to coagulopathy (significant thrombocytopenia), hepatic failure (elevated bilirubin) or renal failure (low urine output or estimated glomerular filtration rate (eGFR) \< 30 mL/min), or significant cardiomyopathy (low cardiac output)
* Use of more than 1 pressor for septic shock (note that use of 1 pressor at low/medium doses for inotropic support due to the use of sedation and paralytics while on the ventilator is allowed)
* Renal failure (eGRF \< 30 mL/min using the Cockcroft-Gault formula for participants ≥ 18 years of age and Schwartz Formula for participants \< 18 years of age) or dialysis or continuous Veno-Venous Hemofiltration)
* Eligible for enrollment in a randomized clinical trial studying remdesivir for treatment of SARS-CoV2 at the medical facility where the participant is admitted
* Known hypersensitivity to the study drug, the metabolites, or formulation excipient
* Requiring venous arterial (V-A) extracorporeal membrane oxygen (ECMO) (venous venous (V-V) ECMO is not an exclusion criteria)

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: University of Alabama- Birmingham
state: Alabama
city: Phoenix
country: United States
facility: Banner- University Medical Center Phoenix
state: Arizona
city: Fresno
country: United States
facility: Community Regional Medical Centers (CRMC)
state: California
city: Fullerton
country: United States
facility: St. Jude Medical Center
state: California
city: La Jolla
country: United States
facility: Scripps Memorial Hospital La Jolla
state: California
city: Long Beach
country: United States
facility: Long Beach Memorial Medical Center
state: California
city: Pasadena
country: United States
facility: Huntington Hospital
state: California
city: San Diego
country: United States
facility: Scripps Mercy Hospital
state: California
city: San Francisco
country: United States
facility: California Pacific Medical Center
state: California
city: San Francisco
country: United States
facility: University of California, Medical Center (Parnassus Campus)
state: California
city: San Jose
country: United States
facility: Regional Medical Center
state: California
city: San Mateo
country: United States
facility: San Mateo Medical Center
state: California
city: Santa Rosa
country: United States
facility: Santa Rosa Memorial Hospital
state: California
city: Thousand Oaks
country: United States
facility: Los Robles Regional Medical Center
state: California
city: Whittier
country: United States
facility: PIH Health Whittier Hospital
state: California
city: Aurora
country: United States
facility: The Medical Center Of Aurora
state: Colorado
city: Denver
country: United States
facility: Rose Medical Center
state: Colorado
city: Englewood
country: United States
facility: Swedish Medical Center
state: Colorado
city: Greenwich
country: United States
facility: Greenwich Hospital
state: Connecticut
city: Middletown
country: United States
facility: Middlesex Health
state: Connecticut
city: New Britain
country: United States
facility: The Hospital of Central Connecticut
state: Connecticut
city: Stamford
country: United States
facility: The Stamford Health Medical Group- Pulmonary Associates
state: Connecticut
city: Washington
country: United States
facility: George Washington University Hospital
state: District of Columbia
city: Aventura
country: United States
facility: Aventura Hospital and Medical Center
state: Florida
city: Fort Pierce
country: United States
facility: Lawnwood Regional Medical Center
state: Florida
city: Hollywood
country: United States
facility: Memorial Regional Hospital
state: Florida
city: Jacksonville
country: United States
facility: Mayo Clinic in Florida
state: Florida
city: Miami Beach
country: United States
facility: Mount Sinai Medical Center
state: Florida
city: Orlando
country: United States
facility: AdventHealth Orlando, Investigational Drug Services
state: Florida
city: Sarasota
country: United States
facility: Sarasota Memorial Hospital
state: Florida
city: Atlanta
country: United States
facility: Piedmont Atlanta Hospital
state: Georgia
city: Atlanta
country: United States
facility: Wellstar Atlanta Medical Center
state: Georgia
city: Columbus
country: United States
facility: Piedmont Columbus Regional-Midtown Hospital
state: Georgia
city: Decatur
country: United States
facility: Grady Health System- Grady Memorial Hospital
state: Georgia
city: Fayetteville
country: United States
facility: Piedmont Fayette Hospital
state: Georgia
city: Savannah
country: United States
facility: Memorial Health University Medical Center
state: Georgia
city: Thomasville
country: United States
facility: John D. Archbold Memorial Hospital
state: Georgia
city: Chicago
country: United States
facility: Swedish Hospital
state: Illinois
city: Chicago
country: United States
facility: Mercy Hospital & Medical Center
state: Illinois
city: Lake Forest
country: United States
facility: Northwestern Lake Forest Hospital
state: Illinois
city: Maywood
country: United States
facility: Loyola University Medical Center
state: Illinois
city: Winfield
country: United States
facility: Northwestern Medicine Central DuPage Hospital
state: Illinois
city: Carmel
country: United States
facility: St. Vincent Hospital and Health Care Center, Inc.
state: Indiana
city: Indianapolis
country: United States
facility: Richard L Roudebush Indianapolis VA
state: Indiana
city: Noblesville
country: United States
facility: Riverview Health
state: Indiana
city: Baton Rouge
country: United States
facility: Our Lady of the Lakes Regional Medical Center
state: Louisiana
city: New Orleans
country: United States
facility: Touro Infirmary
state: Louisiana
city: New Orleans
country: United States
facility: Ochsner Clinic Foundation
state: Louisiana
city: Slidell
country: United States
facility: Slidell Memorial Hospital
state: Louisiana
city: Baltimore
country: United States
facility: University of Maryland
state: Maryland
city: Baltimore
country: United States
facility: Mercy Medical Center
state: Maryland
city: Prince Frederick
country: United States
facility: CalvertHealth Medical Center
state: Maryland
city: Towson
country: United States
facility: University of Maryland St. Joseph Medical Center
state: Maryland
city: Boston
country: United States
facility: Steward St. Elizabeth's Medical Center of Boston, Inc.
state: Massachusetts
city: Cambridge
country: United States
facility: Cambridge Health Alliance
state: Massachusetts
city: Fall River
country: United States
facility: Charlton Memorial Hospital
state: Massachusetts
city: Lawrence
country: United States
facility: Lawrence General Hospital
state: Massachusetts
city: Lowell
country: United States
facility: Lowell General Hospital
state: Massachusetts
city: South Weymouth
country: United States
facility: South Shore Hospital
state: Massachusetts
city: Worcester
country: United States
facility: UMass Memorial Medical Center
state: Massachusetts
city: Ann Arbor
country: United States
facility: St. Joseph Mercy Hospital
state: Michigan
city: Commerce
country: United States
facility: Huron Valley-Sinai Hospital
state: Michigan
city: Detroit
country: United States
facility: Wayne Statue University/ Detroit Receiving Hospital
state: Michigan
city: Detroit
country: United States
facility: Henry Ford Health System
state: Michigan
city: Flint
country: United States
facility: McLaren Health Care Corporation
state: Michigan
city: Kalamazoo
country: United States
facility: Bronson Methodist Hospital
state: Michigan
city: Jackson
country: United States
facility: University of Mississippi Medical Center
state: Mississippi
city: Saint Louis
country: United States
facility: Washington University School of Medicine
state: Missouri
city: Bayonne
country: United States
facility: CarePoint Health Bayonne Medical Center
state: New Jersey
city: Belleville
country: United States
facility: Clara Maass Medical Center
state: New Jersey
city: Camden
country: United States
facility: Cooper University Hospital
state: New Jersey
city: Edison
country: United States
facility: Hackensack Meridian Health - JFK Medical Center
state: New Jersey
city: Elizabeth
country: United States
facility: Trinitas Regional Medical Center
state: New Jersey
city: Englewood
country: United States
facility: Englewood Health
state: New Jersey
city: Flemington
country: United States
facility: Hunterdon Medical Center
state: New Jersey
city: Freehold
country: United States
facility: CentraState Medical Center
state: New Jersey
city: Hamilton
country: United States
facility: Robert Wood Johnson University Hospital Hamilton
state: New Jersey
city: Jersey City
country: United States
facility: Jersey City Medical Center
state: New Jersey
city: Jersey City
country: United States
facility: Christ Hospital- Carepoint Health
state: New Jersey
city: Long Branch
country: United States
facility: Monmouth Medical Center
state: New Jersey
city: Morristown
country: United States
facility: Atlantic Health System/ Morristown Medical Center
state: New Jersey
city: Neptune
country: United States
facility: Jersey Shore University Medical Center
state: New Jersey
city: New Brunswick
country: United States
facility: Saint Peter's University Hospital
state: New Jersey
city: Newark
country: United States
facility: Saint Michael's Medical Center
state: New Jersey
city: Newark
country: United States
facility: University Hospital
state: New Jersey
city: Oakhurst
country: United States
facility: Ocean Medical Center
state: New Jersey
city: Red Bank
country: United States
facility: Bayshore Medical Center
state: New Jersey
city: Ridgewood
country: United States
facility: The Valley Hospital
state: New Jersey
city: Summit
country: United States
facility: Atlantic Health System/Overlook Medical Center
state: New Jersey
city: Teaneck
country: United States
facility: Holy Name Medical Center
state: New Jersey
city: Trenton
country: United States
facility: Capital Health
state: New Jersey
city: Voorhees
country: United States
facility: Virtua Health Voorhees Campus
state: New Jersey
city: Albany
country: United States
facility: St. Peter's Hospital
state: New York
city: Astoria
country: United States
facility: Mount Sinai Queens
state: New York
city: Bay Shore
country: United States
facility: Good Samaritan Hospital Medical Center
state: New York
city: Bay Shore
country: United States
facility: Southside Hospital
state: New York
city: Bronx
country: United States
facility: Lincoln Medical Center
state: New York
city: Bronx
country: United States
facility: St Barnabus Hospital
state: New York
city: Bronx
country: United States
facility: Montefiore Medical Center, Weiler Campus
state: New York
city: Bronx
country: United States
facility: Montefiore Health System Moses Medical Center
state: New York
city: Brooklyn
country: United States
facility: The Brooklyn Hospital Center
state: New York
city: Brooklyn
country: United States
facility: Kingsbrook Jewish Medical Center
state: New York
city: Brooklyn
country: United States
facility: University Hospital Brooklyn (SUNY Downstate)
state: New York
city: Brooklyn
country: United States
facility: Woodhull Medical Center
state: New York
city: Brooklyn
country: United States
facility: Kings County Hospital Center
state: New York
city: Brooklyn
country: United States
facility: New York Harbor VA Medical Center
state: New York
city: Brooklyn
country: United States
facility: Brookdale University Hospital and Medical Center
state: New York
city: Brooklyn
country: United States
facility: Interfaith Medical Center
state: New York
city: Brooklyn
country: United States
facility: NewYork-Presbyterian Brooklyn Methodist Hospital
state: New York
city: Brooklyn
country: United States
facility: Maimonides Medical Center
state: New York
city: Brooklyn
country: United States
facility: NYU Langone Hospital - Brooklyn
state: New York
city: Brooklyn
country: United States
facility: Mount Sinai Brooklyn
state: New York
city: Brooklyn
country: United States
facility: New York City Health and Hospitals - Coney Island
state: New York
city: Buffalo
country: United States
facility: Kaleida Health System
state: New York
city: East Meadow
country: United States
facility: Nassau University Medical Center
state: New York
city: Flushing
country: United States
facility: New York Presbyterian- Queens
state: New York
city: Glens Falls
country: United States
facility: Glens Falls Hospital
state: New York
city: Jamaica
country: United States
facility: Queens Hospital Center
state: New York
city: New York
country: United States
facility: NYU Langone Health
state: New York
city: New York
country: United States
facility: Hospital for Special Surgery
state: New York
city: New York
country: United States
facility: New York City Health and New York City Health and Hospitals - Metropolitan- Metropolitan
state: New York
city: New York
country: United States
facility: NewYork-Presyterian/Columbia University Irving Medical Center- Milstein Hospital
state: New York
city: New York
country: United States
facility: New York City Health + Hospitals / Harlem
state: New York
city: New York
country: United States
facility: New York Presbyterian Lower Manhattan Hospital
state: New York
city: New York
country: United States
facility: Memorial Sloan-Kettering Cancer Center
state: New York
city: Oceanside
country: United States
facility: Mount Sinai South Nassau
state: New York
city: Poughkeepsie
country: United States
facility: Vassar Brothers Medical Center
state: New York
city: Rochester
country: United States
facility: Rochester General Hospital
state: New York
city: Roslyn
country: United States
facility: St. Francis Hospital
state: New York
city: Schenectady
country: United States
facility: Ellis Hospital
state: New York
city: Staten Island
country: United States
facility: Staten Island University Hospital- Northwell Health (North Campus)
state: New York
city: Stony Brook
country: United States
facility: Stony Brook University Hospital/ Stony Brook Children's
state: New York
city: Troy
country: United States
facility: Samaritan Hospital
state: New York
city: Chapel Hill
country: United States
facility: UNC Hospitals
state: North Carolina
city: Charlotte
country: United States
facility: Atrium Health- Carolinas Medical Center
state: North Carolina
city: Cleveland
country: United States
facility: MetroHealth Medical Center
state: Ohio
city: Columbus
country: United States
facility: The Ohio State University College of Medicine
state: Ohio
city: Kettering
country: United States
facility: Kettering Medical Center
state: Ohio
city: Tulsa
country: United States
facility: Saint Francis Hospital
state: Oklahoma
city: Bethlehem
country: United States
facility: St. Luke's Hospital - Bethlehem Campus
state: Pennsylvania
city: Darby
country: United States
facility: Mercy Catholic Medical Center - Fitzgerald Campus
state: Pennsylvania
city: Langhorne
country: United States
facility: St Mary Medical Center
state: Pennsylvania
city: Philadelphia
country: United States
facility: Philadelphia VA Medical Center
state: Pennsylvania
city: Philadelphia
country: United States
facility: Einstein Medical Center Philadelphia
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Allegheny Health Network
state: Pennsylvania
city: Pittsburgh
country: United States
facility: UPMC
state: Pennsylvania
city: Providence
country: United States
facility: Roger Williams Medical Center
state: Rhode Island
city: Warwick
country: United States
facility: Kent Hospital
state: Rhode Island
city: Greenville
country: United States
facility: St. Francis Hospital
state: South Carolina
city: West Columbia
country: United States
facility: Lexington Medical Center
state: South Carolina
city: Nashville
country: United States
facility: TriStar Centennial Medical Center
state: Tennessee
city: Austin
country: United States
facility: St. David's South Austin Medical Center
state: Texas
city: Dallas
country: United States
facility: Texas Health Presbyterian Hospital Dallas
state: Texas
city: Galveston
country: United States
facility: Texas Department of Criminal Justice Hospital (Hospital Galveston)/University of Texas Medical Branch
state: Texas
city: Houston
country: United States
facility: HCA Houston Healthcare West
state: Texas
city: Lubbock
country: United States
facility: Covenant Medical Center
state: Texas
city: Mansfield
country: United States
facility: Methodist Mansfield Medical Center
state: Texas
city: San Antonio
country: United States
facility: Methodist Healthcare System of San Antonio, Ltd. LLP, dha, Methodist Hospital
state: Texas
city: Salt Lake City
country: United States
facility: Saint Mark's Hospital
state: Utah
city: Falls Church
country: United States
facility: Inova Fairfax Medical Campus
state: Virginia
city: Richmond
country: United States
facility: Henrico Doctors Hospital
state: Virginia
city: Roanoke
country: United States
facility: Carilion Medical Center
state: Virginia
city: Bellevue
country: United States
facility: Overlake Hospital Medical Center
state: Washington
city: Seattle
country: United States
facility: University of Washington Medical Center- Montlake Campus
state: Washington
city: Milwaukee
country: United States
facility: Medical College of Wisconsin
state: Wisconsin
city: Darlinghurst
country: Australia
facility: St. Vincent's Hospital Sydney
state: New South Wales
city: Herston
country: Australia
facility: Royal Brisbane and Women's Hospital
state: Queensland
city: Melbourne
country: Australia
facility: The Alfred Hospital
state: Victoria
city: Parkville
country: Australia
facility: The Royal Melbourne Hospital
state: Victoria
city: Southport
country: Australia
facility: Gold Coast Hospital
city: Graz
country: Austria
facility: Landeskrankenhaus Graz West
city: Innsbruck
country: Austria
facility: Universitätsklinik für Innere Medizin II
city: Linz
country: Austria
facility: Kepler Universitätsklinikum
city: Vienna
country: Austria
facility: Medical University and General Hospital Vienna
city: Wien
country: Austria
facility: Sozialmedizinisches Zentrum Süd - Kaiser-Franz-Josef-Spital
city: Brussels
country: Belgium
facility: Centre Hospitalier Universitaire Saint Pierre
city: Ghent
country: Belgium
facility: Ghent University Hospital
city: Hasselt
country: Belgium
facility: Jessa Ziekenhuis
city: Kortrijk
country: Belgium
facility: AZ Groeninge
city: Leuven
country: Belgium
facility: Universitair Ziekenhuis Leuven
city: Liège
country: Belgium
facility: Centre Hospitalier Universitaire de Liège
city: Lodelinsart
country: Belgium
facility: Hôpital Civil Marie Curie
city: Brampton
country: Canada
facility: William Osler Health System
state: Ontario
city: Ottawa
country: Canada
facility: The Ottowa Hospital
state: Ontario
city: Nicosia
country: Cyprus
facility: Nicosia General Hospital
city: Prague
country: Czechia
facility: Všeobecná fakultní nemocnice v Praze
city: Praha 5
country: Czechia
facility: Eticka komise pro multicentircke klinicke hodnoceni Fakultni nemocnice v Motole
city: Praha 8 - Liben
country: Czechia
facility: Nemocnice Na Bulovce
city: Copenhagen
country: Denmark
facility: Rigshospitalet
city: Tallinn
country: Estonia
facility: Põhja-Eesti Regionaalhaigla
city: Tartu
country: Estonia
facility: Vilnius University
city: Bobigny
country: France
facility: Hopital Avicenne
city: Brest Cedex
country: France
facility: Centre Hospitalier Regional Universitaire Brest Hôpital de la Cavale Blanche à Brest
city: Clermont Ferrand
country: France
facility: Centre Hospitalier Universitaire Gabriel-Montpied
city: Colmar
country: France
facility: Hôpitaux Civils de Colmar
city: Corbeil Essonnes
country: France
facility: Centre Hospitalier Sud Francilien
city: Garches
country: France
facility: Hôpital Raymond Poincaré
city: Orléans
country: France
facility: Centre Hospitalier Régional d'Orléans
city: Poitiers
country: France
facility: Centre Hospitalier Universitaire de Poitiers
city: Rouen
country: France
facility: Hôpital Charles-Nicolle
city: Toulouse
country: France
facility: Hôpital Purpan
city: Bochum
country: Germany
facility: Saint Josef Hospital Ruhr Universitaet Bochum
city: Dresden
country: Germany
facility: Universitätsklinikum Carl Gustav Carus Dresden
city: Essen
country: Germany
facility: Universitatsklinikum
city: Freiburg
country: Germany
facility: Universitätsklinikum Freiburg
city: Göttingen
country: Germany
facility: Universitätsmedizin Göttingen
city: Hannover
country: Germany
facility: Medizinische Hochschule Hannover
city: Heidelberg
country: Germany
facility: Universitätsklinikum Heidelberg
city: Homburg
country: Germany
facility: Universitätsklinikum des Saarlandes
city: Regensburg
country: Germany
facility: Caritas-Krankenhaus St. Josef
city: Würzburg
country: Germany
facility: Klinikum Würzburg Mitte
city: Patra
country: Greece
facility: University General Hospital of Patras Panagia I Voithia
city: Thessaloniki
country: Greece
facility: General Hospital of Thessaloniki George Papanikolaou
city: Debrecen
country: Hungary
facility: Kenézy Gyula Kórház És Rendelőintézet
city: Reykjavik
country: Iceland
facility: Landspítali
city: Tralee
country: Ireland
facility: Kerry University Hospital
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center
city: Petah Tikva
country: Israel
facility: Hasharon Hospital
city: Ramat Gan
country: Israel
facility: Sheba Medical Center at Tel Hashomer
city: Ancona
country: Italy
facility: Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona
city: Bari
country: Italy
facility: Azienda Universitaria Ospedaliera Consorziale - Policlinico di Bari
city: Bologna
country: Italy
facility: Azienda Ospedaliero Universitaria
city: Brescia
country: Italy
facility: ASST Spedali Civili di Brescia
city: Catania
country: Italy
facility: Presidio Ospedaliero Garibaldi-Nesima
city: Florence
country: Italy
facility: Azienda Ospedaliero - Universitaria Careggi
city: Genova
country: Italy
facility: Ospedale Policlinico San Martino
city: Milano
country: Italy
facility: Ospedale Maggiore Policlinico
city: Monza
country: Italy
facility: Ospedale San Gerardo di Monza
city: Napoli
country: Italy
facility: Azienda Ospedaliera dei Colli
city: Pisa
country: Italy
facility: Azienda Ospedaliero-Universitaria Pisana
city: Roma
country: Italy
facility: IRCCS Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani
city: Turin
country: Italy
facility: Azienda Ospedaliero Universitaria
city: Kaunas
country: Lithuania
facility: Hospital of Lithuanian University of Health Sciences Kauno klinikos
city: Vilnius
country: Lithuania
facility: Vilnius University
city: Nijmegen
country: Netherlands
facility: Radboud Universitair Medisch Centrum
city: The Hague
country: Netherlands
facility: HagaZiekenhuis
city: Krakow
country: Poland
facility: Szpital Uniwersytecki w Krakowie
city: Lodz
country: Poland
facility: Wojewódzki Specjalistyczny Szpital im. dr. Wł. Biegańskiego
city: Poznan
country: Poland
facility: Wielospecjalistyczny Szpital Miejski Im Józefa Strusia Zakład Opiekuńczo Leczniczy
city: Tychy
country: Poland
facility: Wojewódzki Szpital Specjalistyczny Megrez Sp. z o.o.
city: Lisboa
country: Portugal
facility: Centro Hospitalar Universitário de Lisboa Central - Hospital Curry Cabral
city: Porto
country: Portugal
facility: Centro Hospitalar Universitário do Porto E.P.E.
city: Porto
country: Portugal
facility: Centro Hospitalar Universitário De São João
city: Vila Nova de Gaia
country: Portugal
facility: Centro Hospitalar de Vila Nova de Gaia/Espinho
city: Bucharest
country: Romania
facility: Institutul National de Boli Infectioase Prof. Dr. Matei Bals
city: Iasi
country: Romania
facility: Spitalul Clinic de Boli Infecţioase Sfânta Parascheva Iaşi
city: Timisoara
country: Romania
facility: Clinical hospital for infectious disease
city: Košice
country: Slovakia
facility: Univerzitná Nemocnica L. Pasteura Košice - Pracovisko Rastislavova 43
city: Ljubljana
country: Slovenia
facility: Univerzitetni Klinicni Center Ljubljana
city: Maribor
country: Slovenia
facility: Univerzitetni Klinicni Center Maribor
city: Badalona
country: Spain
facility: Hospital Universitari Germans Trias i Pujol
city: Madrid
country: Spain
facility: Hospital General Universitario Gregorio Maranon
city: Oviedo
country: Spain
facility: Hospital Universitario Central de Asturias
city: Palma de Mallorca
country: Spain
facility: Hospital Universitario Son Espases
city: Salamanca
country: Spain
facility: Hospital Clinico Universitario de Salamanca
city: San Sebastian
country: Spain
facility: Hospital Universitario Donostia
city: Santa Cruz de Tenerife
country: Spain
facility: Hospital Virgen De La Salud
city: Toledo
country: Spain
facility: Hospital Virgen De La Salud
city: Valladolid
country: Spain
facility: Hospital Clinico Universitario de Valladolid
city: Zaragoza
country: Spain
facility: Hospital Universitario Miguel Servet
city: Aarau
country: Switzerland
facility: Kantonsspital Aarau
city: Basel
country: Switzerland
facility: University Hospital Basel
city: Biel
country: Switzerland
facility: Spitalzentrum Biel
city: Chur
country: Switzerland
facility: Kantonsspital Graubünden
city: Lausanne
country: Switzerland
facility: Centre Hospitalier Universitaire Vaudois Lausanne
city: Luzern
country: Switzerland
facility: Luzerner Kantonsspital
city: Sion
country: Switzerland
facility: Hôpital du Valais -Hôpital de Sion
city: Cardiff
country: United Kingdom
facility: University Hospital of Wales, Cardiff and Vale NHS Trust
city: London
country: United Kingdom
facility: Barts Health NHS Trust
city: London
country: United Kingdom
facility: Guy's and St Thomas' NHS Foundation Trust
city: London
country: United Kingdom
facility: St. George's Hospital
city: Southampton
country: United Kingdom
facility: Southampton University Hospital
Study officials:
affiliation: Gilead Sciences
name: Gilead Study Director
role: STUDY_DIRECTOR
References: