Clinical trial NCT01749709: Effect of Daily Music Listening on Stroke Recovery
Official title: Effect of Cognitive Stimulation on Recovery After Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: Stroke
Recovery
Music
Lead sponsor: Turku University Hospital
Sponsor class: OTHER_GOV
Collaborators: name: Academy of Finland
First posted: 2012-12-17
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: TREATMENT

Brief summary: Single blind randomized clinical trial including 50 stroke patients to investigate the effect of daily music listening on behavioral, neural and physiological recovery. Patients are randomized (1:1:1) to listen instrumental or vocal music, or audiobooks (recorded book reading) (control). Outcome measures are change in neuropsychological tests, change in self-reported mood, structural and functional magnetic resonance imaging changes and hormonal changes performed at acute, 3-month and 6-month stages.

Detailed description: Please see above

Eligibility criteria: Inclusion Criteria:

* Acute Hemispheral stroke

Exclusion Criteria:

* Previous neurological or current psychiatric disease,
* severe aphasia

Primary outcomes:
measure: Change in neuropsychological performance (verbal memory)
timeFrame: From acute to 3-month-stage
measure: Change in neuropsychological performance (verbal memory)
timeFrame: From acute to 6-month-stage
Secondary outcomes:
measure: Change in neuropsychological performance (Language skill)
timeFrame: From acute to 3-month-stage
measure: Change in neuropsychological performance (Language skill)
timeFrame: From acute to 3-month-stage
measure: Change in neuropsychological performance (Language skill)
timeFrame: From acute to 3-month-stage
measure: Change in neuropsychological performance (Language skill)
timeFrame: From acute to 6-month-stages
measure: Change in neuropsychological performance (Language skill)
timeFrame: From acute to 6-month-stages
measure: Change in neuropsychological performance (Language skill)
timeFrame: From acute to 6-month-stages
measure: Change in mood
timeFrame: From acute to 3-month-stage
measure: Change in mood
timeFrame: From acute to 6-month-stage
measure: Change in structural gray matter
timeFrame: From acute to 3-month-stage
measure: Change in structural gray matter changes
timeFrame: From acute to 6-month-stage
measure: Change in structural white matter
timeFrame: From acute to 3-month stage
measure: Change in structural white matter
timeFrame: From acute to 6-month stage
measure: Change in neuronal function
timeFrame: From acute to 3-month stage
measure: Change in neuronal function
timeFrame: From acute to 6-month stage
measure: Change in physiological stress level
timeFrame: From acute to 3-month-stage
measure: Change in physiological stress level
timeFrame: From acute to 6-month-stage
measure: Change in physiological stress level
timeFrame: From acute to 3-month-stage
measure: Change in physiological stress level
timeFrame: From acute to 6-month-stage
measure: Change in physiological stress level
timeFrame: From acute to 3-month-stage
measure: Change in physiological stress level
timeFrame: From acute to 6-month-stage
Other outcomes:
Locations:
city: Turku
country: Finland
facility: Turku University Hospital
Study officials:
affiliation: Department of Clinical Neurosciences
name: Valtteri Kaasinen, MD
role: STUDY_CHAIR
References: