Clinical trial NCT06591754: Feasibility, Acceptability, and Preliminary Effects of ISTDP for Personality Disorders in a Specialized Psychiatric Clinic
Official title: A Pilotstudy Investigating Feasability, Acceptability and Preliminary Effects of ISTDP (Intensive Short Term Dynamic Psychotherapy) for Patients with Personality Disorder in a Psychiatric Clinic Specialized on Depression, Anxiety and PTSD
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Personality Disorder
Keywords: Personality disorder
ISTDP
Intensive Short-Term Dynamic Psychotherapy
Lead sponsor: Karolinska Institutet
Sponsor class: OTHER
Collaborators: name: Region Stockholm
name: Stockholm University
First posted: 2024-09-19
Enrollment: 34
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The primary objective of this study is to evaluate the feasibility and acceptability of a 25-week combined group and individual therapy program using Intensive Short-Term Dynamic Psychotherapy (ISTDP) for patients diagnosed with personality disorders. The secondary objective is to investigate preliminary effects of the treatment in terms of reducing symtoms of depression, anxiety and emotion regulation difficulties.

Detailed description: The investigators vill investigate a 25-week treatment with ISTDP that consists of both weekly group- and individual therapy for patients diagnosed with personality disorder in a psychiatric clinic specialized on depression, anxiety and PTSD. The feasibility and acceptability and preliminary effects will be evaluated using a within-group design with repeated measures and qualitative interviews. Patients will be recruited from the clinic and the main inclusion criteria is that the patient have a personality disorder diagnosis.

Eligibility criteria: Inclusion Criteria:

Personality disorder diagnosis (Clinical assessment using STIP-5) Speaks Swedish fluently

Exclusion Criteria:

Autism or intellectual disability Borderline, antisocial or narcissistic personality disorder diagnosis Need for interpreter Urgent social misery Psychotic disorder High suicidality

Primary outcomes:
measure: Patients experience of, and satisfaction with, the treatment assessed through qualitative interviews
timeFrame: Immediately after treatment completion
measure: Depression symtoms
timeFrame: Baseline, weekly throughout treatment, immediately after treatment completion and 6-month follow-up
measure: Participants satisfaction with treatment assessed with the Client Satisfaction Questionnaire (CSQ-8)
timeFrame: Immediately after treatment completion (25 weeks)
measure: Adverse events related to the treatment
timeFrame: From start of treatment up to. 6 month follow up.
measure: Number of individual sessions attended during the treatment
timeFrame: Throughout the treatment period, up to 25 weeks
measure: Number of group sessions attended during the treatment
timeFrame: Throughout the treatment period, up to 25 weeks
measure: Number of dropouts
timeFrame: Throughout the treatment period, up to 25 weeks
measure: Total number of sessions attended during the treatment
timeFrame: Throughout the treatment period, up to 25 weeks
Secondary outcomes:
measure: Fear of negative emotions
timeFrame: Change from baseline to post-treatment (25 weeks) and follow up 6 months after treatment.
measure: Anxiety symtoms
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Emotions regulation difficulties
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Severity of personality disorder
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Symtoms of Borderline Personality disorder
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Severity of personality disorder
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Quality of life
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Quality of life
timeFrame: Change from baseline to immediately after treatment completion (25 weeks) and follow up 6 months after treatment.
measure: Working alliance
timeFrame: Weekly throughout treatment , up to 25 weeks
measure: Emotional activation during therapy
timeFrame: Weekly throughout treatment, up to 25 weeks
Other outcomes:
Locations:
city: Stockholm
country: Sweden
facility: Affektiva, ångest och traumaprogrammet, Psykiatri Sydväst
Study officials:
References: