Clinical trial NCT06340100: Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes
Official title: Association of History of Concussion With Vestibular Impairment and Cognitive Function in Sports Athletes
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Concussion, Mild
Vestibular Impairment
Cognitive Impairment
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-04-01
Enrollment: 115
Sex: ALL
Minimum age (years): 18
Maximum age (years): 36
Standard ages: ADULT
Observational model: OTHER
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: This includes information such as age, gender, and ethnicity of the athletes. Understanding the demographics of the population helps in assessing the generalizability of the study findings across different groups.

The number, severity, and timing of previous concussions experienced by each athlete. This helps in stratifying the participants based on concussion history and assessing potential cumulative effects.

Pre-existing medical conditions, history of previous injuries (e.g., musculoskeletal injuries), and baseline cognitive and physical performance measures. This information allows for controlling potential confounding variables and assessing the impact of concussion independently.

Brief summary: This study investigates the potential relationship between prior concussions and their impact on both vestibular function and cognitive abilities in athletes participating in sports.

Detailed description: The association of a history of concussions with vestibular impairment and cognitive function in sports athletes is a significant area of research due to the potential long-term consequences of head injuries in contact sports.

Vestibular impairment refers to disruptions in the balance and spatial orientation system of the inner ear, which can result from head trauma. Cognitive function encompasses various mental processes, including memory, attention, and decision-making, which may be affected by concussions.

This study aims to examine how prior concussions relate to both vestibular impairment and cognitive function in athletes participating in sports. Researchers typically employ a combination of self-reported concussion history, clinical assessments of vestibular function, and standardized cognitive tests to evaluate participants.

Findings from such studies can provide valuable insights into the potential effects of concussions on athletes' balance, spatial awareness, and cognitive abilities. Understanding these associations can inform concussion management protocols, rehabilitation strategies, and preventive measures in sports settings.

Furthermore, this research may contribute to the development of targeted interventions aimed at improving vestibular rehabilitation and cognitive training for athletes with a history of concussions. By identifying and addressing these potential deficits early, athletes may reduce their risk of long-term complications and optimize their performance and well-being in sports.

Eligibility criteria: Inclusion Criteria:

* athletes actively involved in sports at age of 18 to 35
* active players in contact sports

Exclusion Criteria:

* Concussion other than sports
* History of recent fractures.
* Participants having neurological deficits

Primary outcomes:
measure: CANTU
timeFrame: 3 DAYS
measure: Sports concussion office assesment tool 6
timeFrame: 3-30days
Secondary outcomes:
Other outcomes:
Locations:
city: Peshawar
country: Pakistan
facility: HAYATABAD Sports complex
state: Khyber Pakhtun Khawan
Study officials:
affiliation: Riphah International University
name: Maheen gul, MSSPT*
role: PRINCIPAL_INVESTIGATOR
References:
citation: Whitney SL, Eagle SR, Marchetti G, Mucha A, Collins MW, Kontos AP; CARE Consortium Investigators. Association of acute vestibular/ocular motor screening scores to prolonged recovery in collegiate athletes following sport-related concussion. Brain Inj. 2020 May 11;34(6):840-845. doi: 10.1080/02699052.2020.1755055. Epub 2020 Apr 21.
citation: Taylor KM, Kioumourtzoglou MA, Clover J, Coull BA, Dennerlein JT, Bellinger DC, Weisskopf MG. Concussion History and Cognitive Function in a Large Cohort of Adolescent Athletes. Am J Sports Med. 2018 Nov;46(13):3262-3270. doi: 10.1177/0363546518798801. Epub 2018 Sep 19.
citation: Price AM, Knell G, Caze TJ 2nd, Abt JP, Loveland D, Burkhart SO. Exploring Vestibular/Ocular and Cognitive Dysfunction as Prognostic Factors for Protracted Recovery in Sports-Related Concussion Patients Aged 8 to 12 Years. Clin J Sport Med. 2022 Jul 1;32(4):408-414. doi: 10.1097/JSM.0000000000000975. Epub 2021 Sep 8.
citation: Yorke AM, Smith L, Babcock M, Alsalaheen B. Validity and Reliability of the Vestibular/Ocular Motor Screening and Associations With Common Concussion Screening Tools. Sports Health. 2017 Mar/Apr;9(2):174-180. doi: 10.1177/1941738116678411. Epub 2016 Nov 11.
citation: Eagle SR, Nindl BC, Johnson CD, Kontos AP, Connaboy C. Does Concussion Affect Perception-Action Coupling Behavior? Action Boundary Perception as a Biomarker for Concussion. Clin J Sport Med. 2021 May 1;31(3):273-280. doi: 10.1097/JSM.0000000000000731.
citation: Zhang Y, Ma Y, Chen S, Liu X, Kang HJ, Nelson S, Bell S. Long-Term Cognitive Performance of Retired Athletes with Sport-Related Concussion: A Systematic Review and Meta-Analysis. Brain Sci. 2019 Aug 13;9(8):199. doi: 10.3390/brainsci9080199.
citation: Louey AG, Cromer JA, Schembri AJ, Darby DG, Maruff P, Makdissi M, Mccrory P. Detecting cognitive impairment after concussion: sensitivity of change from baseline and normative data methods using the CogSport/Axon cognitive test battery. Arch Clin Neuropsychol. 2014 Aug;29(5):432-41. doi: 10.1093/arclin/acu020. Epub 2014 May 9.
citation: Harmon KG, Clugston JR, Dec K, Hainline B, Herring S, Kane SF, Kontos AP, Leddy JJ, McCrea M, Poddar SK, Putukian M, Wilson JC, Roberts WO. American Medical Society for Sports Medicine position statement on concussion in sport. Br J Sports Med. 2019 Feb;53(4):213-225. doi: 10.1136/bjsports-2018-100338.
citation: Bryan MA, Rowhani-Rahbar A, Comstock RD, Rivara F; Seattle Sports Concussion Research Collaborative. Sports- and Recreation-Related Concussions in US Youth. Pediatrics. 2016 Jul;138(1):e20154635. doi: 10.1542/peds.2015-4635. Epub 2016 Jun 20.
citation: Kerr ZY, Roos KG, Djoko A, Dalton SL, Broglio SP, Marshall SW, Dompier TP. Epidemiologic Measures for Quantifying the Incidence of Concussion in National Collegiate Athletic Association Sports. J Athl Train. 2017 Mar;52(3):167-174. doi: 10.4085/1062-6050-51.6.05. Epub 2016 Jun 22.