Clinical trial NCT04134611: Use of Hyaluronic Acid Injection in Lateral Patellar Compression With Femoral Condylar Degenerative Changes After Arthroscopic Release
Official title: Use of Hyaluronic Acid Injection After Arthroscopic Lateral Release in Patellar Compression Syndrome With Degenerative Cartilage Changes: Randomized Control Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anterior Knee Pain Syndrome
Keywords: Hyaluronic acid injection
Knee Arthroscopy
lateral patellar retinaculae.
lateral patellar compression syndrome
Lead sponsor: Hawler Medical University
Sponsor class: OTHER
First posted: 2019-10-22
Enrollment: 90
Sex: ALL
Minimum age (years): 26
Maximum age (years): 47
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two groups (A and B). Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, and Group B (45 patients) were no injection intraarticular.

Detailed description: This study was done by one orthopedic surgeon in two hospitals. Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two matched groups (A and B) regarding the age and gender; Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, 2 weeks after arthroscopy and were followed by VAS of knee pain for one year at (3) months, (6) months and (12) months, and Group B (45 patients) were no injection intraarticular. The study started on June (2017) and ends on March (2020). injection of Hyaluronic acid was used and followed in the same way. All patients presented with anterior knee pain which failed to respond to conservative treatment for 6 weeks or recurrent of symptoms after stopping of conservative treatment which involved changes of life style and NSAID. MRI done for all patients before operation.

Eligibility criteria: Inclusion Criteria:

* Lateral patellar compression syndrome

Exclusion Criteria:

* Patellar instability.
* Smoking.
* Diabetes Mellitus.
* Previous knee surgery.

Primary outcomes:
measure: Visual analogue score of knee pain
timeFrame: The VAS for knee pain was measured 24 months after operation
measure: Kujala score
timeFrame: Preoperative assessment and 2 year postoperatively
Secondary outcomes:
Other outcomes:
Locations:
city: Erbil
country: Iraq
facility: Sherwan Hamawandi
Study officials:
References:
citation: Hamawandi SA. Use of hyaluronic acid injection after arthroscopic release in lateral patellar compression syndrome with degenerative cartilage changes: randomized control trial. BMC Musculoskelet Disord. 2021 Jan 6;22(1):24. doi: 10.1186/s12891-020-03876-0.