Clinical trial NCT02269761: Chest Ultrasound of ER Patients With Cough or SOB
Official title: Prospective Evaluation With Ultrasound of Emergency Department Patients Presenting With Cough or Dyspnea
Study type: OBSERVATIONAL
Overall status: TERMINATED
Conditions: Cough
Dyspnea
Wheezing
Keywords: Emergency Departments
Chest
Lung
Cough
Dyspnea
Wheezing
Ultrasound
Ultrasonography
Lead sponsor: University of Washington
Sponsor class: OTHER
Collaborators: name: Philips Healthcare
First posted: 2014-10-21
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Emergency Department (ED) patients with shortness of breath (SOB)

Brief summary: Acute dyspnea (shortness of breath) is a common complaint for patients presenting to the Emergency Department (ED). The chest radiograph (CXR) has been the mainstay in evaluating patients with shortness of breath and often provides the timely diagnosis of pneumonia, pneumothorax, pulmonary edema, among other primary diseases of the lung. There are limitations with chest radiograph such as large body mass (e.g, obesity) and patient positioning. On occasion, chest radiography findings are difficult to interpret. Lung ultrasonography may offer a means of clarifying ambiguous results.

The objective of this study to determine the usefulness of point of care lung ultrasound in evaluating patients presenting to the ED with shortness of breath, cough and/or wheezing.

Detailed description: Acute dyspnea (shortness of breath) is a common complaint for patients presenting to the Emergency Department (ED). The chest radiograph (CXR) has been the mainstay in evaluating patients with shortness of breath and often provides the timely diagnosis of pneumonia, pneumothorax, pulmonary edema, among other primary diseases of the lung. There are limitations with chest radiograph such as large body mass (e.g, obesity) and patient positioning. On occasion, chest radiography findings are difficult to interpret. Lung ultrasonography may offer a means of clarifying ambiguous results. Advantages of ultrasound include real-time immediate evaluation, it is non-invasive and does not use radiation.

The investigators seek to perform a prospective evaluation of patients presenting to the University of Washington Medical Center ED for cough, wheezing and/or shortness of breath.

The objective of this study to determine the usefulness of point of care lung ultrasound in evaluating patients presenting to the ED with shortness of breath, cough and/or wheezing.

The specific aim of this study is to further define the utility of point-of-care ultrasound in the evaluation of emergency department patients presenting with cough, wheezing and/or shortness of breath. The investigators will compare ultrasound results to radiograph and tomography results when available, and to the physicians initial impression.

Eligibility criteria: Inclusion Criteria:

* Presenting to the Emergency Department with cough, wheezing and/or dyspnea (shortness of breath)
* Referred for CXR and/or CT scan

Exclusion Criteria:

* Life threatening medical condition requiring immediate treatment
* Unable to sit up for a chest ultrasound
* Unable to consent
* Pregnant
* Unable to speak, read and write in English

Primary outcomes:
measure: B-lines on chest ultrasound as a predictor of pulmonary edema and/or pneumonia
timeFrame: Up to 1 week
Secondary outcomes:
Other outcomes:
Locations:
city: Seattle
country: United States
facility: University of Washington Medical Center
state: Washington
Study officials:
affiliation: University of Washington
name: Theodore J Dubinsky, MD
role: PRINCIPAL_INVESTIGATOR
References: