Clinical trial NCT03196856: Brock Exercise And Supplement Trials
Official title: Effects of Greek Yogurt and Exercise on Muscle Size, Body Composition and Bone Health in Untrained, University-aged Males
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Untrained
Healthy
Keywords: Greek Yogurt
Muscle Size
Bone Health
Body Composition
Exercise
Lead sponsor: Brock University
Sponsor class: OTHER
First posted: 2017-06-23
Enrollment: 30
Sex: MALE
Minimum age (years): 18
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized Controlled Trial
Primary purpose: TREATMENT

Brief summary: This study will analyze the effects of Greek yogurt consumption and an 12 week exercise intervention on muscle size, body composition and bone health in untrained, university-aged males.

Detailed description: Introduction: Previous research has shown the effectiveness of dairy milk and whey protein on increasing muscle size, optimizing body composition and increasing strength in adult males. However, evidence on the use of high protein/Greek yogurt on muscle size, body composition and bone health is limited in this population. Yogurt contains similar muscle and bone supporting nutrients as milk, yet it offers a host of additional benefits including; increased satiety, probiotic cultures, greater stability, increased variety, more affordable and versatile features such as acting as a vehicle for consumption of other healthful foods. The proposed research will investigate the use of Greek yogurt as an effective post-exercise food to promote healthy body composition and bone health changes in young adult males.

Design: Parallel, randomized controlled trial.

Participants: 30 (n=15 YOG, n=15 PLA) healthy, untrained university-aged males.

Methods: Subjects will undergo a 12-week resistance and plyometric training program (exercising 3 days/week). The YOG group will consume a 200g dose (pro= 20g, carbs= 8 grams, \~110 kcals) of plain 0% Greek yogurt, while the PLA group will consume an isoenergetic, protein-void beverage comprised mainly of maltodextrin (pro= 0g, carbs= 26g, \~110 kcals). Each group will consume 3 doses per day (immediately and 1 hour post-exercise, and bedtime). Markers of bone health (CTx and P1NP) will be taken at baseline, 1 week and 12 weeks to determine acute and total changes. Muscle size, body composition, strength, vertical jump height and nutritional diaries will be measured pre and post intervention and habitual diet maintenance will be encouraged throughout the intervention.

Anticipated Results: It is hypothesized that each group will undergo positive changes in the aforementioned measures, however due to the increase in protein and calcium consumption, the yogurt group is predicted to have significantly greater increases in these variables than the placebo group.

Eligibility criteria: Inclusion Criteria:

* Male
* Age 18-25 years
* Normal BMI (18.5-24.9) kg/m2
* Have not participated in a resistance training program (of resistance exercise at least 2x/week or more) in the last 6 months
* Healthy and not taking any medication affecting muscle or bone
* Not supplementing with vitamins/ minerals or protein
* Speak and understand English
* No dairy allergy or lactose intolerance

Primary outcomes:
measure: Muscular Strength
timeFrame: Change from Baseline to 12 weeks
measure: Muscle Size
timeFrame: Change from Baseline to 12 weeks
measure: Body Composition
timeFrame: Change from Baseline to 12 weeks
Secondary outcomes:
measure: Bone cell activity
timeFrame: Change from Baseline to 12 weeks
measure: Vertical Jump Height
timeFrame: Change from Baseline to 12 weeks
Other outcomes:
Locations:
city: St. Catharines
country: Canada
facility: Brock University
state: Ontario
Study officials:
affiliation: Brock University
name: Andrea Josse, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bridge A, Brown J, Snider H, Nasato M, Ward WE, Roy BD, Josse AR. Greek Yogurt and 12 Weeks of Exercise Training on Strength, Muscle Thickness and Body Composition in Lean, Untrained, University-Aged Males. Front Nutr. 2019 Apr 30;6:55. doi: 10.3389/fnut.2019.00055. eCollection 2019.