Clinical trial NCT06864871: Complications in Minimally Invasive Aesthetic Dermatological Procedures in Switzerland
Official title: Complications in Minimally Invasive Aesthetic Dermatological Procedures in Switzerland: A Descriptive Study From a University Referral Center
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Aesthetic Procedures
Complication of Treatment
Keywords: Minimally Invasive Procedures
Injectable Procedures
Non-injectable Procedures
Complications
Lead sponsor: University Hospital, Basel, Switzerland
Sponsor class: OTHER
First posted: 2025-03-07
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients that had an appointment at Margarethenklinik of the University Hospital Basel between January 2021 and December 2024.

Brief summary: The aim of this retrospective study is to describe cases of complications from minimally invasive aesthetic procedures treated at a university reference centre in Switzerland between 2021 and 2024.

Detailed description: During the past decade, a steady increase in aesthetic procedures has been observed. Over the last four years, non-surgical procedures have grown by 40%. The five most popular treatments are botulinum toxin, hyaluronic acid, hair removal, chemical peels, and nonsurgical fat reduction.

With the increase in aesthetic procedures, adverse effects have also increased. Contributing factors include weak regulations, unlicensed practice, and individuals with little or no formal training administering botulinum toxins and dermal fillers.

This study aims to analyze unexpected and often unfavorable outcomes, referred to as complications, arising from minimally invasive procedures-both non-injectable (e.g., laser treatments, chemical peels) and injectable (e.g., botulinum toxin, fillers). The complications are categorized based on their severity and ethiology. This retrospective case series is conducted at a university reference center in Switzerland (Margarethenklinik of the University Hospital Basel) between January 2021 and December 2024.

Eligibility criteria: Inclusion Criteria:

* Patients aged 18 and older of all genders, ethnic and social demographic background that have signed the General consent and the Photo-Informed Consent Form.

Exclusion Criteria:

* Patients who didn't sign the general consent.
* Patients under 18 years old.

Primary outcomes:
measure: Total cases of complications
timeFrame: Between January 2021 and December 2024
measure: Type of aesthetic procedure
timeFrame: Between January 2021 and December 2024
measure: Diagnosis of complication
timeFrame: Between January 2021 and December 2024
Secondary outcomes:
measure: Location of aesthetic procedure (Switzerland or abroad)
timeFrame: Between January 2021 and December 2024
measure: Type of practitioner performing the aesthetic procedure
timeFrame: Between January 2021 and December 2024
Other outcomes:
Locations:
city: Basel
country: Switzerland
facility: Margarethenklinik, University Hospital Basel
Study officials:
affiliation: Margarethenklinik, University Hospital Basel
name: Roberta Vasconcelos Berg, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: