Clinical trial NCT06549933: The Effect of Cryostimulation on Inflammation and Motor Functions. The Study Was Conducted to Determine the Effect of Five Days of Whole-body Cryostimulation (PBC) on Reducing Inflammation and Improving Motor Skills in Soccer Players
Official title: The Influence of Cryostimulation on Reducing Inflammation and Improving Motor Skills in Football Player
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Rest
Training
Keywords: cryostimulation
regeneration
football players
inflammation
motor functions
Lead sponsor: Poznan University of Physical Education
Sponsor class: OTHER
First posted: 2024-08-12
Enrollment: 21
Sex: MALE
Minimum age (years): 18
Maximum age (years): 36
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Athletes undergoing regular training were divided into two groups. One of them was subjected to cryotherapy treatments, the other was a control group, not subjected to any treatments at that time.
Primary purpose: OTHER

Brief summary: The aim of the study was to determine the effect of a 5-day PBC on reducing inflammation and improving motor skills in soccer players during the initial phase of the training period.

The five-day cryostimulation applied did not significantly affect the profile of inflammatory markers in soccer players. However, a reduction in visuo-motor reaction time (RT) was registered in PBC-treated soccer players, suggesting the potential benefits of this method in improving motor skills.

Detailed description: Cryostimulation is one of the methods of post-exercise recovery, involving short-term (3 min) exposure of the body to extremely low temperatures, oscillating between -100°C and -190°C. The purpose of this therapy is to reduce inflammation, reduce physical and mental fatigue and use it as a passive form of preparing the body for further exercise as part of the training process.

The study was conducted to determine the effect of five days of whole-body cryostimulation (PBC) on reducing inflammation and improving motor skills in soccer players. A group of 24 football players was randomly divided into a test group (PBC; -140°C ± 20°C, 3 min, 5 days) and a control group (CON). Before the cryostimulation session, both groups were subjected to visual-motor ability tests, which were repeated on the last day of the study. Blood samples were collected at four time points (P0-1 day, P1-3 day, P2-5 day, P3-2 days after the test). Levels of creatine kinase (CK), tumor necrosis factor (TNFα), interleukins (IL-6, IL-10), testosterone (T) and cortisol (C) were determined in the samples.

Eligibility criteria: Inclusion Criteria:

* athletes
* no previous experience with systemic cryotherapy
* any other forms of recovery or cosmetic treatments

Exclusion Criteria:

* alcohol or any other stimulants
* anti-inflammation drugs
* injuries

Primary outcomes:
measure: IL-6 (Interleukin-6)
timeFrame: Before, after 3 days and 5 days of cryostimulation
measure: TNF-alpha (Tumor necrosis factor-alpha)
timeFrame: Before, after 3 days and 5 days of cryostimulation
measure: IL-10 (Interleukin-10)
timeFrame: Before, after 3, and 5 days of cryostimulation
measure: CK (creatine kinase)
timeFrame: Before, after 3, and 5 days of cryostimulation
measure: Cortisol
timeFrame: Before, after 3, and 5 days of cryostimulation
measure: Testosterone
timeFrame: Before, after 3, and 5 days of cryostimulation
Secondary outcomes:
measure: Anthropometric measurments
timeFrame: Before, after 3, and 5 days of cryostimulation
Other outcomes:
Locations:
city: Poznań
country: Poland
facility: Poznań University of Physical Education
Study officials:
affiliation: Poznan University of Physical Education
name: Izabela Różycka
role: PRINCIPAL_INVESTIGATOR
References: