Clinical trial NCT05221983: COVID-19 and Vitamin D: Length of Hospital Stay and Mortality
Official title: Vitamin D Level: Reflections of a Public Health Issue in the COVID-19 Pandemic. Does it Affect Mortality and Length of Hospital Stay?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: COVID-19 Pandemic
Vitamin D Deficiency
Keywords: COVID-19
Vitamin D
Length of stay
Mortality
Lead sponsor: Yuksek Ihtisas University
Sponsor class: OTHER
Collaborators: name: Ankara City Hospital Bilkent
First posted: 2022-02-03
Enrollment: 168
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Adult patients with positive COVID-19 PCR (Polymerase Chain Reaction) test and vitamin D level in biochemical parameters, who applied to Ankara City Hospital Neurology-Orthopedics Hospital between 01 August and 31 October 2020.

Brief summary: The lack of a pharmacological treatment in the COVID-19 pandemic has pushed scientists to search for this issue. Maintaining optimal health is parallel to adequate and balanced nutrition. In this context, can the protective properties of vitamin D play an important role in this pandemic? brought with it the thought. In this study, it was aimed to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease.

Detailed description: This research was conducted to examine the effect of vitamin D on mortality and hospital stay in COVID-19 disease. For this, the approval of the Ministry of Health and then the ethics committee was obtained. For this reason, patients with positive PCR tests and hospitalized patients with vitamin D levels in their biochemistry were included in the study.

The data of the patients were obtained from the medical records. Information such as age, gender, comorbidities, length of hospital stay, vitamin D level were included in the study. According to the statistical analyzes obtained from these data, it has been shown that vitamin D level has no effect on mortality and hospital stay in COVID-19 disease.

Eligibility criteria: Inclusion Criteria:

* COVID-19 PCR (Polymerase Chain Reaction) test positive
* Vitamin D level in biochemical parameters
* Adult patients hospitalized for COVID-19

Exclusion Criteria:

-Patients using drugs that may affect vitamin D absorption, such as corticosteroids, cholesterol-lowering agents, phenobarbital and phenytoin-containing agents

Primary outcomes:
measure: Level of Vitamin D
timeFrame: 1 month later
measure: Relationship between vitamin D level and mortality
timeFrame: 1 month later
measure: Relationship between vitamin D level and hospital stay
timeFrame: 1 month later
Secondary outcomes:
measure: Effects of additional diseases (Diabetes mellitus, hypertension, etc.) on hospital stay and mortality
timeFrame: 1 month later.
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Republic of Turkey Ministry of Health Ankara City Hospitals Neurology-Orthopedics Hospital
Study officials:
affiliation: Republic of Turkey Ministry of Health Ankara City Hospitals Neurology-Orthopedics Hospital
name: Levent Öztürk, MD
role: STUDY_DIRECTOR
References: