Clinical trial NCT05311007: Intrahospital Transport in Patients With High-flow Nasal Oxygenation: Prospective Observational Study
Official title: Intrahospital Transport in Patients With High-flow Nasal Oxygenation: Prospective Observational Study.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Critical Illness
Keywords: High-flow nasal oxygenation
intra-hospital transport
critical ill patients
intensive care units
Lead sponsor: Centre Hospitalier Régional d'Orléans
Sponsor class: OTHER
First posted: 2022-04-05
Enrollment: 175
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients requiring intra-hospital transfer on high-flow nasal oxygen therapy will be eligible to participate in the study

Brief summary: High-flow nasal oxygen therapy is commonly used in intensive care unit (ICU). Intra-hospital transfer of critical patients is frequent: 1) to perform diagnostic 2) between emergency room or medical wards and ICU. During theses transfers, oxygenation should be continued.

There is high-flow nasal oxygen therapy for transport using an external battery. This mode of operation in transport mode allows about 30-45 min of autonomy.

Intra-hospital transport under high-flow nasal oxygen therapy has been previously described on children.

The objective of this study is to evaluate the occurrence of complications during intra-hospital transports under high-flow nasal oxygen of critical patients.

Detailed description: High-flow nasal oxygen therapy is commonly used in intensive care unit (ICU). Intra-hospital transfer of critical patients is frequent: 1) to perform diagnostic 2) between emergency room or medical wards and ICU. During theses transfers, oxygenation should be continued.

There is high-flow nasal oxygen therapy for transport using an external battery. This mode of operation in transport mode allows about 30-45 min of autonomy.

Intra-hospital transport under high-flow nasal oxygen therapy has been previously described on children.

The objective of this study is to evaluate the occurrence of complications during intra-hospital transports under high-flow nasal oxygen of critical patients.

Eligibility criteria: Inclusion Criteria:

* Patient treated with high-flow nasal oxygen therapy before the intra-hospital transport prior to transport
* Requiring an intra-hospital transport (e.g., CT scan, OR, etc.) or inter-departmental transport supervised by the ICU team

Nb: Once the patient is included in the study, any intra-hospital transport under high-flow nasal oxygen therapy will be analyzed until discharge from the intensive care unit and at until D28.

Exclusion Criteria:

* Under 18 years old
* Patient being under guardianship, tutorship or curatorship
* Pregnancy or breastfeeding
* Lack of social security number
* Refusal to participate in the study

Primary outcomes:
measure: Incidence of severe adverse events during intra-hospital transport
timeFrame: Up to 28 days
Secondary outcomes:
measure: Incidence of minor adverse events during intra-hospital transport
timeFrame: Up to 28 days
Other outcomes:
Locations:
city: DAX
country: France
facility: Hospital Center of DAX
city: Martigues
country: France
facility: CH de Martigues
city: Orléans
country: France
facility: CHR d'ORLEANS
city: Vannes
country: France
facility: CH Bretagne Atlantique vannes-Auray
Study officials:
affiliation: CHU d'Orléans
name: Mai-Anh NAY, Dr
role: PRINCIPAL_INVESTIGATOR
References: