Clinical trial NCT05190497: Effects of IMT on Pulmonary Functions IN CASES With Inhalation Injury
Official title: Effects of Inspiratory Muscle Training on Clinical Predictors of Respiratory Muscle Strength and Lung Function in Burned Patients With Inhalation Injury
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Inhalation Injury
Pulmonary Function
Respiratory Muscle Strength
Keywords: INSPIRATORT TRAINING -INHALATION INJURY
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2022-01-13
Enrollment: 40
Sex: ALL
Minimum age (years): 20
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The exercise group received inspiratory muscle training in addition to routine chest physiotherapy (group A).

The Control group received only routine chest physiotherapy (group B).
Primary purpose: TREATMENT

Brief summary: The current study aimed to investigate the effect of inspiratory muscle training (IMT) on pulmonary functions (FEV1and FVC), and respiratory muscle strength in patients with inhalation injury, which may prove to be a promising intervention helping to improve exercise tolerance, relieve dyspnea and suggests an improvement in respiratory muscle function.

Detailed description: Forty male patients suffering from inhalation injury were been included in this study, Participants' ages ranged from 20-35 years old. Patients were selected from the burn department, Om El-Masreen hospital, and randomly assigned into two equal groups.

The exercise group received inspiratory muscle training in addition to routine chest physiotherapy in the form of (deep breathing, coughing, and early ambulation) three times per week for four weeks (group A). The Control group received only routine chest physiotherapy (group B). This study obtained ethical approval by the institutional review board of the Faculty of Physical Therapy - Cairo University, with reference number: P.T.REC/012/003431

Eligibility criteria: Inclusion criteria:

* Male patients suffering from inhalation injury.
* Participant age ranged from 20-35 years old.
* All patients had the same medical care.
* Participants have received a good explanation of the treatment and measurement device.
* Treatment was conducted one month after inhalation injury.

Exclusion criteria:

Patients were excluded from this study for any of the following cases such as

* Instability of patient's medical condition.
* Presence of any diseases that could affect the study results.
* Participants having respiratory, cardiac, or neurological diseases that affect pulmonary functions.

Primary outcomes:
measure: PULMONARY FUNCTION TEST
timeFrame: 3 MONTHS
measure: Respiratory muscles Strength Measurement
timeFrame: 3 MONTHS
Secondary outcomes:
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Khaled Takey Ahmed
Study officials:
affiliation: Cairo University
name: Maha A El monem, Ass Prof
role: STUDY_CHAIR
References:
citation: Gupta K, Mehrotra M, Kumar P, Gogia AR, Prasad A, Fisher JA. Smoke Inhalation Injury: Etiopathogenesis, Diagnosis, and Management. Indian J Crit Care Med. 2018 Mar;22(3):180-188. doi: 10.4103/ijccm.IJCCM_460_17.