Clinical trial NCT03119493: Periodized Aerobic Interval Training in Metabolic Syndrome
Official title: Effects of Periodized Aerobic Interval Training on Autonomic Modulation and Cardiovascular and Anthropometric Variables in Individuals With Metabolic Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Metabolic Syndrome
Metabolic Syndrome X
Keywords: Metabolic syndrome X
Autonomic nervous system
Aerobic exercise
Exercise
Heart rate
Lead sponsor: Universidade Estadual Paulista Júlio de Mesquita Filho
Sponsor class: OTHER
First posted: 2017-04-18
Enrollment: 52
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Autonomic disfunction present in metabolic syndrome subjects is related by a greater vulnerability of the heart and risk of cardiovascular events. In this context, aerobic interval training has been highlighted by its easy applicability and benefits effects in autonomic modulation in different populations. Therefore the studies that use de aerobic interval training in this different populations didn't realize a periodization of training with preparatory periods with progressive increase of load, specific phases with less duration predominating the intensity and transition periods for recuperation. Additionally, there isn't studies that investigate the effects of aerobic interval training in autonomic modulation of individuals with metabolic syndrome. In this context, periodized aerobic interval training can arise like a new type of treatment that offering security and efficacy in subjects with metabolic syndrome. So, the aim of the study is evaluate the effect of periodized aerobic interval training in cardiac autonomic modulation and cardiovascular and anthropometric parameters of individuals with metabolic syndrome.


Eligibility criteria: Inclusion Criteria:

* Metabolic syndrome according to international diabetes federation (IDF) definition
* Aged between 40 to 60 years

Exclusion Criteria:

* Participants who are currently participating in any regular exercise programs last six months;
* Use of drugs or medication (Except for risk factors of metabolic syndrome control);
* Inflammatory or infectious process;
* Musculotendinous or osteoarticular injuries in the lower limbs and/or spine;
* Chronic pulmonary disease;
* Neurological disorders;
* Cardiovascular disease.

Primary outcomes:
measure: Heart rate variability
timeFrame: 16 week after allocation
Secondary outcomes:
measure: Cardiovascular parameter : heart rate
timeFrame: 16 week after allocation
measure: Cardiovascular parameter: blood pressure
timeFrame: 16 week after allocation
measure: Anthropometric parameter: hit waist ratio
timeFrame: 16 week after allocation
measure: Anthropometric parameter: abdominal circumference
timeFrame: 16 week after allocation
measure: Anthropometric parameter: body mass index
timeFrame: 16 week after allocation
Other outcomes:
Locations:
city: Presidente Prudente
country: Brazil
facility: Laís Manata Vanzella
state: São Paulo
Study officials:
affiliation: Universidade Estadual Paulista - UNESP campus de Presidente Prudente
name: Luiz Carlos M Vanderlei, PHD
role: STUDY_DIRECTOR
References:
citation: Vanzella LM, Linares SN, Miranda RAT, Silva AKFD, Christofaro DGD, Netto Junior J, Vanderlei LCM. Effects of a new approach of aerobic interval training on cardiac autonomic modulation and cardiovascular parameters of metabolic syndrome subjects. Arch Endocrinol Metab. 2019 Mar-Apr;63(2):148-156. doi: 10.20945/2359-3997000000111. Epub 2019 Mar 21.