Clinical trial NCT03653598: BLITZ Atrial Fibrillation
Official title: BLITZ Atrial Fibrillation
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Atrial Fibrillation
Keywords: Atrial Fibrillation
Lead sponsor: Heart Care Foundation
Sponsor class: OTHER
First posted: 2018-08-31
Enrollment: 4125
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All consecutive hospitalized patients with Atrial Fibrillation

Brief summary: Management strategies for AF have made many advances over the last decade but there is still a great heterogeneity in the management of AF and it remains unclear how often clinicians adhere to current guidelines.

A survey of an updated AF management would enable a timely assessment of implementation of current International guidelines, allow monitoring of early management of AF when a patients is admitted in a Emergency Room (ER) and Cardiology Unit.

Detailed description: Multicentre, observational study. 200 Italian Hospitals fully representing the Italian cardiology reality in terms of geographical distribution and level of hospital technology.

Data collection in ER: Data on AF and Atrial Flutter episodes in ER will be collected retrospectively by checking the records of ER without collection of any data that can allow to identify the patients. These data will be collected under the responsibility of the Cardiology Departments consecutively for 4 weeks.

Data collected in Cardiology: these data will be collected under the responsibility of the Cardiology Departments for 12 weeks consecutively.

Eligibility criteria: Inclusion Criteria:

* All patients with AF, admitted to cardiology wards for an urgent or planned hospitalization.
* All patients admitted in a Day Hospital regimen for treatment of AF The diagnosis of AF must be confirmed by ECG.
* Signed Patient Inform Consent.

Exclusion Criteria:

* The qualifying episode of AF was not documented with an ECG.
* Age \<18 years.
* Patients with AF as a complication of an acute coronary syndrome (within 1 week from symptoms onset).
* Patients with AF associated with cardiothoracic surgery (within 1 week from surgery).
* Concomitant participation in other studies that can modify the diagnostic and/or therapeutic treatments.
* Patients already enrolled in BLITZ-AF

Primary outcomes:
measure: Number of admissions of patients with AF
timeFrame: Enrollemnt
measure: Rate or rhythm control strategy
timeFrame: Baselane study completion - average 1 week
measure: Antithrombotic strategies
timeFrame: Baselane study completion - average 1 week
Secondary outcomes:
measure: Admission to the ER for atrial flutter
timeFrame: Enrollment
measure: Patients regularly followed up by the cardiology centers
timeFrame: 12 months
measure: Adherence to the 1A recommendations of current guidelines
timeFrame: 12 months
Other outcomes:
Locations:
city: Agrigento
country: Italy
facility: Ospedale San Giovanni Di Dio - Uo Cardiologia E Utic
state: AG
city: Casale Monferrato
country: Italy
facility: Ospedale Santo Spirito - Sc Cardiologia
state: AL
city: Fabriano
country: Italy
facility: Ospedale Civile Profili - U.O. Cardiologia
state: AN
city: Jesi
country: Italy
facility: Ospedale Di Jesi Carlo Urbani - U.O. Di Cardiologia
state: AN
city: Senigallia
country: Italy
facility: Ospedale Principe Di Piemonte - Uoc Cardiologia Utic
state: AN
city: Aosta
country: Italy
facility: Ospedale Generale Regionale-Po U. Parini - U.O. Cardiologia E Cure Intensive Card.
state: AO
city: Ascoli Piceno
country: Italy
facility: Ospedale Gen.Le Prov.Le C.G. Mazzoni - Sc Cardiologia
state: AP
city: Cortona
country: Italy
facility: Ospedale Valdichiana Santa Margherita - Uos Cardiologia E Hdu
state: AR
city: Ariano Irpino
country: Italy
facility: Po Sant'Ottone Frangipane - U.O.C. Cardiologia - Utic
state: AV
city: Avellino
country: Italy
facility: Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'
state: AV
city: Altamura
country: Italy
facility: Ospedale Della Murgia - Fabio Perinei - S.C. Cardiologia-Utic
state: BA
city: Bari
country: Italy
facility: Ospedale San Paolo - Cardiologia-Utic
state: BA
city: Bari
country: Italy
facility: Ospedale Policlinico - U.O. Di Cardiologia Ospedaliera
state: BA
city: Corato
country: Italy
facility: Ospedale Umberto I - Uosd Di Cardiologia
state: BA
city: Molfetta
country: Italy
facility: P.O. Don Tonino Bello - Uosd Cardiologia
state: BA
city: Osio Sotto
country: Italy
facility: Iob - Policlinico San Marco - U.O. Cardiologia
state: BG
city: Belluno
country: Italy
facility: Ospedale Civile - Sc Cardiologia
state: BL
city: Feltre
country: Italy
facility: Ospedale Santa Maria Del Prato - U.O. Di Cardiologia
state: BL
city: Benevento
country: Italy
facility: Azienda Ospedaliera G. Rummo - Cardiologia Interventistica E Utic
state: BN
city: Bologna
country: Italy
facility: Ospedale Maggiore - Uo Di Cardiologia
state: BO
city: Bologna
country: Italy
facility: Ospedale Bellaria - U.O. Di Cardiologia
state: BO
city: Brindisi
country: Italy
facility: Ospedale Perrino - U.O.C. Di Cardiologia
state: BR
city: Francavilla Fontana
country: Italy
facility: Ospedale Civile Dario Camberlingo - U.O. Di Cardiologia - Utic
state: BR
city: Gardone Val Trompia
country: Italy
facility: Ospedale Di Gardone Val Trompia - Ssvd Cardiologia
state: BS
city: Andria
country: Italy
facility: Osp. Andria Canosa - Po Andria - Cardiologia - Utic
state: BT
city: Barletta
country: Italy
facility: Ospedale Monsignor Angelo R. Di Miccoli - Unita' Operativa Di Cardiologia
state: BT
city: Bisceglie
country: Italy
facility: Ospedale Vittorio Emanuele Ii - Cardiologia
state: BT
city: Bolzano
country: Italy
facility: Ospedale Generale Regionale - Divisione Di Cardiologia
state: BZ
city: Cagliari
country: Italy
facility: Presidio Ospedaliero Ss Trinita' - Sc Di Cardiologia
state: CA
city: Caserta
country: Italy
facility: Az. Ospedaliera S. Anna E S. Sebastiano - U.O. Cardiologia-Utic
state: CE
city: Santa Maria Capua Vetere
country: Italy
facility: Ospedale San Giuseppe E Melorio - U.O.C. Cardiologia Utic
state: CE
city: Sessa Aurunca
country: Italy
facility: Presidio Ospedaliero San Rocco - U.O.C. Cardiologia - Utic
state: CE
city: Lanciano
country: Italy
facility: Ospedale 'Renzetti' - Cardiologia E Utic
state: CH
city: Caltanissetta
country: Italy
facility: Ospedale S. Elia - U.O.C Cardiologia - Utic
state: CL
city: Gravedona
country: Italy
facility: Ospedale Moriggia Pelascini - Unita' Operativa Di Cardiologia
state: CO
city: Crema
country: Italy
facility: Ospedale Maggiore - U.O. Cardiologia E Utic
state: CR
city: Cremona
country: Italy
facility: Ospedale Di Cremona - Uo Di Cardiologia
state: CR
city: Paola
country: Italy
facility: Ospedale Spoke Paola- Cetraro Po Paola - Utic Cardiologia
state: CS
city: Catania
country: Italy
facility: P.O. Garibaldi-Nesima - U.O.C. Di Cardiologia
state: CT
city: Catania
country: Italy
facility: Azienda Ospedaliera Cannizzaro -
state: CT
city: Nicosia
country: Italy
facility: Ospedale G. Basilotta - U.O.C. Di Cardiologia
state: EN
city: Cento
country: Italy
facility: Ospedale Ss. Annunziata - U.O. Di Cardiologia
state: FE
city: Cerignola
country: Italy
facility: Ospedale Civile Giuseppe Tatarella - U.O. Di Cardiologia - Utic
state: FG
city: Foggia
country: Italy
facility: Ospedali Riuniti - S.C. Di Cardiologia Univ.-Utic
state: FG
city: Fermo
country: Italy
facility: Ospedale Civile Augusto Murri - U.O. Cardiologia
state: FM
city: Monfalcone
country: Italy
facility: Ospedale Civile San Polo - S.O.C. Cardiologia
state: GO
city: Merate
country: Italy
facility: Ospedale San Leopoldo Mandic - Cardiologia - Ucc
state: LC
city: Casarano
country: Italy
facility: Presidio Ospedaliero F. Ferrari - Cardiologia - Utic
state: LE
city: Copertino
country: Italy
facility: Ospedale San Giuseppe Da Copertino - U.O. Di Cardiologia-Utic
state: LE
city: Galatina
country: Italy
facility: Ospedale Santa Caterina Novella - U.O. Di Cardiologia
state: LE
city: Gallipoli
country: Italy
facility: Ospedale Civile Sacro Cuore Di Gesu' - Uo Cardiologia Utic
state: LE
city: Scorrano
country: Italy
facility: Ospedale Ignazio Veris Delli Ponti - Uoc Cardiologia-Utic
state: LE
city: Piombino
country: Italy
facility: Ospedale Villamarina - Cardiologia E Utic
state: LI
city: Lido Di Camaiore
country: Italy
facility: Nuovo Ospedale Versilia - Sc Cardiologia
state: LU
city: Carate Brianza
country: Italy
facility: Ospedale Carate Brianza - Cardiologia- Carate Brianza/Giussano
state: MB
city: Monza
country: Italy
facility: Ospedale San Gerardo - U.O. Cardiologia-Utic
state: MB
city: Monza
country: Italy
facility: Policlinico Di Monza - Uo Cardiol. Clinica E Scompenso Cardiaco
state: MB
city: Civitanova Marche
country: Italy
facility: Presidio Osp. Di Civitanova Marche - Sc Cardiologia
state: MC
city: Patti
country: Italy
facility: Ospedale Barone Romeo - Divisione Di Cardiologia E Utic
state: ME
city: Sant'Agata Di Militello
country: Italy
facility: P.O. Sant'Agata Di Militello - Uoc Cardiologia
state: ME
city: Milano
country: Italy
facility: Centro Cardiologico Monzino - Scompenso,Cardiologia Clinica, Riabilit.
state: MI
city: Milano
country: Italy
facility: Ospedale San Luca - Istituto Auxologico - U.O. Cardiologia
state: MI
city: Milano
country: Italy
facility: Ospedale San Carlo Borromeo - Cardiologia-Ucc
state: MI
city: Rho
country: Italy
facility: Ospedale Civile - Unita' Operativa Di Cardiologia
state: MI
city: Sesto San Giovanni
country: Italy
facility: Irccs Policlinico Multimedica - Uo Di Cardiologia
state: MI
city: Castiglione Delle Stiviere
country: Italy
facility: Ospedale San Pellegrino - U.O. Cardiologia
state: MN
city: Modena
country: Italy
facility: Ospedale Policlinico - Uo Cardiologia
state: MO
city: Modena
country: Italy
facility: Ospedale Civile Di Baggiovara - U.O. Di Cardiologia
state: MO
city: Sassuolo
country: Italy
facility: Ospedale Di Sassuolo - Cardiologia
state: MO
city: Massa
country: Italy
facility: Ftgm - Stabilimento Di Massa - Uoc Cardiologia Diagn. E Interventistica
state: MS
city: Nuoro
country: Italy
facility: Ospedale San Francesco - Cardiologia - Utic
state: NU
city: Olbia
country: Italy
facility: Ospedale Giovanni Paolo Ii - Utic - Cardiologia
state: OT
city: Partinico
country: Italy
facility: Ospedale Civico - U.O. Cardiologia
state: PA
city: Camposampiero
country: Italy
facility: Ospedale Di Camposampiero - U.O.A. Cardiologia
state: PD
city: Cittadella
country: Italy
facility: Ospedale Di Cittadella - U.O. Cardiologia
state: PD
city: Monselice
country: Italy
facility: Ospedali Riuniti Padova Sud - U.O.C. Cardiologia
state: PD
city: Piove Di Sacco
country: Italy
facility: Ospedale Civile Immacolata Concezione - Cardiologia E Utic
state: PD
city: Penne
country: Italy
facility: Ospedale Civile San Massimo - Ambulatorio Di Cardiologia
state: PE
city: Città Di Castello
country: Italy
facility: Presidio Ospedaliero Citta' Di Castello - U.O. Di Cardiologia
state: PG
city: Foligno
country: Italy
facility: Nuovo Ospedale San Giovanni Battista - S.C. Cardiologia
state: PG
city: Pescia
country: Italy
facility: Ospedale Della Val Di Nievole - U. O. Cardiologia - Utic
state: Point
city: Pistoia
country: Italy
facility: Ospedale San Jacopo - U.O. Cardiologia
state: Point
city: Pavia
country: Italy
facility: Fondazione Irccs Policlinico San Matteo - Card. Con Ucc-Lab. Ricerca Sperim. Card.
state: PV
city: Vigevano
country: Italy
facility: Ospedale Civile - Cardiologia
state: PV
city: Melfi
country: Italy
facility: Ospedale S. Giovanni Di Dio - U.O. Cardiologia E Utic
state: PZ
city: Potenza
country: Italy
facility: Azienda Ospedaliera San Carlo - Uo Cardiologia Utic E Cardiostimolazione
state: PZ
city: Locri
country: Italy
facility: Ospedale Civile - S.O.C. Cardiologia-Utic
state: RC
city: Polistena
country: Italy
facility: Ospedale Santa Maria Degli Ungheresi - U.O. Di Cardiologia
state: RC
city: Reggio Calabria
country: Italy
facility: Ao Bianchi Melacrino Morelli- Po Riuniti - Divisione Di Cardiologia
state: RC
city: Reggio Calabria
country: Italy
facility: Policlinico Madonna Della Consolazione - U.O. Di Cardiologia
state: RC
city: Correggio
country: Italy
facility: Ospedale Civile San Sebastiano - Sos Cardiologia Area Nord
state: RE
city: Guastalla
country: Italy
facility: Ospedale Civile - Sc Cardiologia Area Nord
state: RE
city: Reggio Emilia
country: Italy
facility: Arcispedale Santa Maria Nuova - S.C. Cardiologia
state: RE
city: Vittoria
country: Italy
facility: Ospedale Riccardo Guzzardi - U.O.C. Di Cardiologia-Utic
state: RG
city: Albano Laziale
country: Italy
facility: Aslrm6-Polo H2 Albano-Genzano - U.O.C. Di Cardiologia E Utic
state: RM
city: Civitavecchia
country: Italy
facility: Ospedale Civile San Paolo - U.O. Cardiologia - Utic
state: RM
city: Colleferro
country: Italy
facility: Ospedale L. Parodi Delfino - U.O. Complessa Di Cardiologia - Utic
state: RM
city: Frascati
country: Italy
facility: Ospedale San Sebastiano Martire - U.O. Cardiologia - Utic
state: RM
city: Pomezia
country: Italy
facility: Policlinico Citta' Di Pomezia S. Anna - U.O. Cardiologia-Utic
state: RM
city: Roma
country: Italy
facility: Campus Biomedico - Cardiologia
state: RM
city: Roma
country: Italy
facility: P.O. San Filippo Neri - Asl Roma 1 - Uoc Cardiologia E Utic
state: RM
city: Roma
country: Italy
facility: Ospedale San Camillo - Uoc Cardiologia 1
state: RM
city: Roma
country: Italy
facility: Policlinico Umberto Primo - Cardiologia B - Cardiologia E Angiologia
state: RM
city: Roma
country: Italy
facility: Aurelia Hospital - U.O.C Cardiologia
state: RM
city: Roma
country: Italy
facility: Policlinico Agostino Gemelli - Cardiologia Intensiva
state: RM
city: Roma
country: Italy
facility: Ao San Giovanni Addolorata - Cardiologia E Riab. Cardiologica
state: RM
city: Roma
country: Italy
facility: Ospedale Fatebenefratelli - U.O.C. Cardiologia
state: RM
city: Tivoli
country: Italy
facility: Ospedale San Giovanni Evangelista - U.O.C. Di Cardiologia - Utic
state: RM
city: Porto Viro
country: Italy
facility: Casa Di Cura Madonna Della Salute - Cardiologia
state: RO
city: Rovigo
country: Italy
facility: Ospedale Santa Maria Della Misericordia - U.O.C. Cardiologia
state: RO
city: Battipaglia
country: Italy
facility: Presidio Osped. S. Maria Della Speranza - U.O. Di Cardiologia
state: SA
city: Eboli
country: Italy
facility: Ospedale Maria Ss. Addolorata - U.O. Di Cardiologia Utic
state: SA
city: Mercato San Severino
country: Italy
facility: Ospedale G. Fucito - U.O. Di Cardiologia E Utic
state: SA
city: Salerno
country: Italy
facility: Aou S. Giovanni Di Dio-Ruggi D'Aragona - Cardiologia Interventistica - Emodinamic
state: SA
city: Vallo Della Lucania
country: Italy
facility: Ospedale San Luca - U.O. Utic - Cardiologia
state: SA
city: Montepulciano
country: Italy
facility: Ospedali Riuniti Della Valdichiana Senese - Cardiologia E Utic
state: SI
city: Poggibonsi
country: Italy
facility: Ospedale Dell'Alta Val D'Elsa - Uosd Cardiologia-Utic
state: SI
city: Sondrio
country: Italy
facility: Ospedale Civile - U.O. Cardiologia
state: SO
city: Sarzana
country: Italy
facility: Ospedale San Bartolomeo - U.O. Cardiologia Clinica-Riabilitativa
state: SP
city: Augusta
country: Italy
facility: Ospedale E. Muscatello - U.O. Di Cardiologia - Utic
state: SR
city: Avola
country: Italy
facility: Ospedale G. Di Maria - Cardiologia Utic
state: SR
city: Manduria
country: Italy
facility: Ospedale Civile M. Giannuzzi - Cardiologia E Utic
state: TA
city: Taranto
country: Italy
facility: Ospedale Ss. Annunziata - S.C. Cardiologia-Utic
state: TA
city: Teramo
country: Italy
facility: Ospedale Civile G. Mazzini - Cardiologia Utic Ed Emodinamica
state: TE
city: Rovereto
country: Italy
facility: Ospedale Santa Maria Del Carmine - Cardiologia
state: TN
city: Ciriè
country: Italy
facility: Por Cirie'- Lanzo Presidio Cirie' - S.C. Cardiologia Cirie'- Ivrea
state: TO
city: Ivrea
country: Italy
facility: Ospedale Civile - S.C. Cardiologia Cirie' Ivrea
state: TO
city: Rivoli
country: Italy
facility: Ospedale Degli Infermi - Sc Cardiologia
state: TO
city: Alcamo
country: Italy
facility: Ospedale Ss. Vito E Spirito - U.O.S. Di Cardiologia
state: TP
city: Orvieto
country: Italy
facility: Ospedale S. Maria Della Stella - Sc Di Cardiologia
state: TR
city: Terni
country: Italy
facility: Azienda Ospedaliera Santa Maria - S.C. Di Cardiologia
state: TR
city: Trieste
country: Italy
facility: Ospedali Riuniti - Osp. Cattinara - S.O.C. Cardiologia
state: TS
city: Udine
country: Italy
facility: Pou Santa Maria Della Misericordia - S.O.C. Cardiologia
state: UD
city: Gallarate
country: Italy
facility: Ospedale S. Antonio Abate - U.O. Di Cardiologia
state: VA
city: Saronno
country: Italy
facility: Presidio Ospedaliero Di Saronno - U.O.C. Di Cardiologia
state: VA
city: Tradate
country: Italy
facility: Ospedale Di Circolo Galmarini - Cardiologia
state: VA
city: Varese
country: Italy
facility: Ospedale Di Circolo E Fondazione Macchi - Cardiologia I
state: VA
city: Varese
country: Italy
facility: Ospedale Di Circolo E Fondazione Macchi - Ssd Unita' Di Cure Intensive Coronariche
state: VA
city: Mestre
country: Italy
facility: Ospedale Dell'Angelo - U.O. Cardiologia
state: VE
city: Portogruaro
country: Italy
facility: Ospedale Civile - Ambulatori Cardiologia
state: VE
city: Venezia
country: Italy
facility: Ospedale Civile Di Venezia - U.O. Di Cardiologia
state: VE
city: Arzignano
country: Italy
facility: Ospedale Civile - U.O.C. Cardiologia
state: VI
city: Bassano Del Grappa
country: Italy
facility: Ospedale San Bassiano - Struttura Complessa Di Cardiologia
state: VI
city: Santorso
country: Italy
facility: Ospedale Alto Vicentino - U.O.C. Cardiologia - Ucic
state: VI
city: San Bonifacio
country: Italy
facility: Ospedale G. Fracastoro - U.O.C. Di Cardiologia
state: VR
city: Borgomanero
country: Italy
facility: Ospedale Ss. Trinita' - S.C. Di Cardiologia
city: Giugliano In Campania
country: Italy
facility: Ospedale Generale Di Zona - U.O. Cardiologia - Utic
city: Napoli
country: Italy
facility: Ospedale Buon Consiglio Fatebenefratelli - U.O.Complessa Di Cardiologia E Utic
city: Napoli
country: Italy
facility: Aorn Osp. Dei Colli- Po Vincenzo Monaldi - U.O.C. Cardiologia - S.U.N.
city: Napoli
country: Italy
facility: Aorn Osp. Dei Colli- Po Vincenzo Monaldi - U.O.C. Cardiologia
city: Napoli
country: Italy
facility: Ospedale Del Mare - U.O. Cardiologia Con Utic
city: Napoli
country: Italy
facility: Fondazione Evangelica Betania - Uos Cardiologia
city: Novara
country: Italy
facility: Aou Maggiore Della Carita' - Cardiologia Ii
city: San Giuseppe Vesuviano
country: Italy
facility: Casa Di Salute Santa Lucia - U.O. Cardiologia
Study officials:
affiliation: Heart Care Foundation
name: Michele M Gulizia, MD
role: STUDY_CHAIR
References:
citation: Gulizia MM, Cemin R, Colivicchi F, De Luca L, Di Lenarda A, Boriani G, Di Pasquale G, Nardi F, Scherillo M, Lucci D, Fabbri G, Maggioni AP; BLITZ-AF Investigators. Management of atrial fibrillation in the emergency room and in the cardiology ward: the BLITZ AF study. Europace. 2019 Feb 1;21(2):230-238. doi: 10.1093/europace/euy166.
citation: Cemin R, Colivicchi F, Maggioni AP, Boriani G, De Luca L, Di Lenarda A, Di Pasquale G, Fabbri G, Lucci D, Gulizia MM; On the behalf of BLITZ-AF Investigators. One-year clinical events and management of patients with atrial fibrillation hospitalized in cardiology centers: Data from the BLITZ-AF study. Eur J Intern Med. 2020 Apr;74:55-60. doi: 10.1016/j.ejim.2019.12.006. Epub 2020 Jan 14.