Clinical trial NCT05525871: Effects of Nitrates and Citrulline Malate on Performance in Professional Professional Soccer
Official title: Experimental Study to Evaluate the Effects of Effects of a Sports Supplement Based on Nitrates and Citrulline Malate on Performance in Professional Soccer Players
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Supplementation
Keywords: Nitrates
Citrulline malate
Soccer
Lead sponsor: Universidad Católica San Antonio de Murcia
Sponsor class: OTHER
First posted: 2022-09-02
Enrollment: 40
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Randomized, single-center, parallel, team-stratified, stratified experimental study to evaluate the efficacy of a high sports supplement in improving high-intensity intermittent exercise performance in professional female soccer players.

Detailed description: Subjects who meet the selection criteria will be randomly assigned to each of the study groups (investigational product or placebo, depending on the group to which they have been assigned).

The product to be consumed will be Nitrates and Citrulline Malate. Participants will consume the product for 30 days. The intake should be done two hours before each training session and the same dose will be consumed.

The women's soccer players will perform a stress test with gas analysis to measure performance, as well as a Wingate test without consumption of the products. Five days later, the players will perform the Yo-Yo IR1 test in the field and will repeat the same tests performed at the beginning of the test after product consumption.

Eligibility criteria: Inclusion Criteria:

* Present at the time of signing the informed consent at the age between 18 and 40 years.
* Female.
* Healthy subjects without any chronic disease.
* Volunteers capable of understanding the clinical study, willing to give their written informed. consent and comply with the procedures and requirements of the study. and requirements of the study.

Exclusion Criteria:

* Players who change teams during the experimental study.
* Smoking subjects.
* Subjects using mouthwashes during the study.
* Subjects with a history of drug, alcohol or other substance abuse or other factors that limit their ability to cooperate during the study. factors that limit their ability to cooperate during the study.
* Subjects whose status makes them ineligible for the study, at the discretion of the investigator discretion of the investigator.

Primary outcomes:
measure: Aerobic and anaerobic thresholds - VO2max
timeFrame: Change in initial maximal oxygen consumption at 30 days
measure: Fatigue in jumping
timeFrame: Change in initial jump fatigue at 30 days
measure: Anaerobic capacity
timeFrame: Change in baseline anaerobic capacity at 30 days
Secondary outcomes:
measure: Microcapillary blood
timeFrame: It will be measured on two different occasions. Day one and 30 days later.
measure: Lactate
timeFrame: It will be measured on two different occasions. One on the first day (without intake of product ) and 30 days later, the same measurements but after having consumed the product
measure: Safety variables
timeFrame: It will be measured on two different occasions. Day one and 30 days later.
Other outcomes:
Locations:
city: Murcia
country: Spain
facility: Catholic University of Murcia
Study officials:
References: