Clinical trial NCT06764433: Greater Occipital Nerve Pulsed Radiofrequency in Cervicogenic Headache
Official title: Efficacy of Greater Occipital Nerve Pulsed Radiofrequency Treatment At C2 Level in Cervicogenic Headache
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Headache, Cervicogenic
Cervicogenic Headache
Keywords: Cervicogenic headache, proximal GON PRF, Ultrasound guided, C2 level
Lead sponsor: Ankara City Hospital Bilkent
Sponsor class: OTHER
First posted: 2025-01-08
Enrollment: 25
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Single-center, prospective, comparative, observational study
Primary purpose: TREATMENT

Brief summary: The effect of GON PRF treatment applied with USG-guided proximal technique in patients who do not respond to conservative treatments for cervicogenic headache

Detailed description: In our study, GON PRF will be applied to volunteers who are diagnosed with cervicogenic headache according to ICHD-3 criteria, who meet the study criteria and who report a positive effect with diagnostic GON block application. The main purpose of our study is to evaluate the clinical efficacy and safety of ultrasound-guided C2 level greater occipital nerve pulsed radiofrequency treatment in cervicogenic headache during the follow-up period. Our secondary purpose is to determine the effects of the GON PRF treatment we applied on the volunteers' analgesic drug consumption, daily life activities and sleep, how they generally perceive this treatment and whether there is a need for any additional treatment.

Eligibility criteria: Inclusion Criteria:

* Diagnosed with cervicogenic headache according to ICHD-3 criteria
* Cranial and cervical spine imaging is available
* Number of headache days per month 5 and/or more
* Inadequate benefit from pharmacological treatments or physical therapy methods used
* Volunteer patients who can understand and approve the treatment and the informed consent form and who can comply with the treatment

Exclusion Criteria:

* History of secondary headache other than cervicogenic headache according to ICHD-3 criteria
* Cervical nerve root irritation and/or spinal stenosis symptoms and signs
* Sensory deficit findings in the greater occipital nerve dermatome
* Craniocervical defect or other anatomical abnormality in the target area or nearby the procedure
* Local or systemic infection
* Received nonpharmacological treatment within the last 3 months (physical therapy, botulinum toxin A, acupuncture, ozone, cognitive behavioral therapy, etc.)
* Pregnancy or suspected pregnancy
* Known allergy to local anesthetic drugs
* History of malignancy
* Known organic disease of the brain and spinal cord
* History of cranial/cervical surgery within the last 1 year
* Bleeding-clotting disorder or oral anticoagulant use
* Comorbid disease that may cause headache (uncontrolled hypertension, intracranial lesion, etc.)
* Compliance with treatment and treatment results diseases that may affect the evaluation (psychiatric disorder, dementia, etc.)
* Those who request re-treatment due to the emergence of contralateral pain or other types of pain during the follow-up period after treatment
* Those who do not accept treatment

Primary outcomes:
measure: Visual Analog Scale
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Health Sciences University, Ankara Bilkent City Hospital
state: Cankaya
Study officials:
References:
citation: Gabrhelik T, Michalek P, Adamus M. Pulsed radiofrequency therapy versus greater occipital nerve block in the management of refractory cervicogenic headache - a pilot study. Prague Med Rep. 2011;112(4):279-87.