Clinical trial NCT04687371: The Effect of Proprioseptive Vestibular Rehabilitation in Patients With Peripheral Vestibular Hypofunction
Official title: The Effect of Proprioseptive Vestibular Rehabilitation on the Balance, Functional Mobility, Posture, Sensory Profile and Quality of Life in Patients With Vertigo Due to Peripheral Vestibular Hypofunction
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Vertigo, Peripheral
Vestibular Disease
Keywords: Vertigo
Peripheral Vestibular Hypofunction
Exercises
Balance
Functional Mobility
Quality of Life
Lead sponsor: Inonu University
Sponsor class: OTHER
First posted: 2020-12-29
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Experimental, Randomized Controlled Study
Primary purpose: TREATMENT

Brief summary: The aim of this study was to investigate the effect of proprioceptive vestibular rehabilitation on balance, functional mobility, posture, sensory profile and quality of life in patients with vertigo due to peripheral vestibular hypofunction.

Detailed description: Peripheral vestibular system; It forms the part extending from the structures in the inner ear to the vestibular nuclei in the brainstem. Peripheral vestibular hypofunction is a chronic disease affecting one or both sides of the vestibular system, which occurs when the function of the vestibular organs, vestibular nerve, or both is reduced or destroyed. Many patients with peripheral vestibular hypofunction develop symptoms such as dizziness, vertigo, imbalance, gait disturbance. Many different exercise methods have been tried so far to relieve these symptoms and increase the functionality of the patient. In this study, we aimed to examine the effect of proprioceptive vestibular rehabilitation on balance, quality of life, posture, sensory profile and functional mobility in patients with vertigo due to peripheral vestibular hypofunction aged 18-65 years. Patients with vertigo due to peripheral vestibular hypofunction between the ages of 18-65 will be included in our study. The population of the research will be created by the cluster sampling method and the randomization of the patients to be recruited will be determined using the "research ramdomizer" computer program; Patients will be divided into 3 groups as experimental and control groups. A randomized controlled, single-blind study will be planned. Group I (experiment): Glance stabilization exercises, Cawthorne Cooksey Exercises and Proprioceptive vestibular rehabilitation exercises, Group II (experiment): Glance stabilization exercises and Cawthorne Cooksey Exercises and Group III (control): no exercise will be given, they will be asked to continue daily life. Exercises will be applied to each group for 8 weeks, 4 days a week, 30 minutes, in the presence of 1 set of physiotherapists and as a home exercise program every day of the week. Individuals will be evaluated before and 8 weeks after the treatment. Tinetti Balance Test for balance assessment, One leg stand test; timed up and go test for functional mobility assessment; Dizziness Disability Inventory for quality of life; mobile posture assessment application for posture assessment; Adult / Adolescent Sensory profile will be used for sensory assessment. Pre- and post-treatment and intergroup evaluations will be compared, and the effectiveness of proprioceptive vestibular rehabilitation on balance, functional mobility, posture, sensory profile and quality of life, and its superiority over standard exercises will be interpreted.

Eligibility criteria: Inclusion Criteria:

* Between 18-65 years
* Diagnosis of vertigo according to the clinical examination performed by an Otorhinolaryngologist, Vestibular Evoked Myogenic Potentials (VEMP), Video Head Impulse Test (VHIT)
* Patients with Unilateral Peripheral Hypofunction
* After giving detailed information about the research, agreeing to participate in the study.

Exclusion Criteria:

* Severe hearing / vision impairment-loss
* Patients with neurological, orthopedic, circulatory system problems that may cause vertigo, dizziness and balance disorders
* Having severe hypertension / diabetes
* Previous participation in a vestibular rehabilitation program
* Being healthy
* Patients using drugs that may affect the treatment negatively
* Refusing to participate in a clinical trial
* Patients who cannot adapt to the training program
* Patients who discontinued their treatment
* Patients with different diagnoses that may disrupt the treatment during the study

Primary outcomes:
measure: Dizziness handicap inventory
timeFrame: 8 weeks
measure: Tinetti balance test
timeFrame: 8 weeks
measure: Time up and go test
timeFrame: 8 weeks
measure: Adolescent/Adult Sensory Profile
timeFrame: 8 weeks
measure: Mobile application for Posture Analyze
timeFrame: 8 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Malatya
country: Turkey
facility: Inonu University
state: Battalgazi/MALATYA
Study officials:
affiliation: Inonu University
name: Burcu TALU, Assoc. Prof.
role: PRINCIPAL_INVESTIGATOR
References: