Clinical trial NCT02849561: Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest
Official title: Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest : Prospective Study of Routine Care
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cardio Respiratory Arrest
Keywords: Pupillary light reflex
Cardio respiratory arrest
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
First posted: 2016-07-29
Enrollment: 82
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: FACTORIAL

Brief summary: With the repercussion of 55 cases eachyear for 100 000 inhabitants in France, cardio respiratory arrest is a public health issue.

The goal of this study is to evaluate the pupillary light reflex measured by the dimension of the pupil (diameter) as a prognosis factor neurological evolution in post cardiac arrest. By participating to this study, the patient get the same tratments and exams than in a usual managing cares.

In addition of these events, the pupillary light reflex is studied as soon as the patient is accepted in the department, and then on the second day.

Currently, the evaluation of the neurological becoming rely on a multimodal clinical and paraclinical approach.

The study of the pupillary light reflex measured by the diameter of the pupil could be a prognosis factor of neurological evolution for patients in post cardiac arrest, so a reliable and available prognosis marker in patient care.

The goal of this study is to evaluate the pupillary light reflex (RPM), measured by the diameter of the pupil as a prognosis factor of neurological evaluation of admitted patients after a cardiac arrest.

Principal criteria of judgement is the percentage of the pupillary light reflex variation measured with Neurolight®, compared between two groups.


Eligibility criteria: Inclusion Criteria:

* Both gender
* Entry in resuscitation after a cardiac arrest intra or extra-hospital
* Resumption of a spontaneous cardiac activity
* Affiliation to a social security system

Exclusion Criteria:

* Refusal from patient or his family
* Age under 18 years
* Pregnant women
* Previous neurological damages
* Persons deprived of liberty by judicial or administrative decision

Primary outcomes:
measure: Percentage of the pupillary light reflex variation measured with Neurolight®
timeFrame: One second
Secondary outcomes:
Other outcomes:
Locations:
city: La Tronche
country: France
facility: UniversityHospitalGrenoble
Study officials:
affiliation: Grenoble Hospital University
name: Michel Durand, Doctor
role: PRINCIPAL_INVESTIGATOR
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