Clinical trial NCT06610292: Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients
Official title: Effects of Pharmacist-led Medication Reconciliation Services on Geriatric Patients At a Leading Military Hospital in Jordan
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Geriatric Patients
Medication Reconcilitation Upon Hospital Admission
Medication Reconciliation At Discharge
Pharmacist-led Medication Reconciliation
Keywords: Medication reconciliation
Geriatrics
Geriatric patients
Jordan
Tertiary military hospital
Pharmacist-led medication reconciliation
Lead sponsor: University of Jordan
Sponsor class: OTHER
Collaborators: name: Jordanian Royal Medical Services
name: Royal Medical Services, Jordanian Armed Forces
First posted: 2024-09-24
Enrollment: 128
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This study aims to assess the effects of Pharmacist-led medication reconciliation on hospitalized elderly patients aged above 65 at a leading tertiary military hospital in Jordan.

Detailed description: A four-month randomized controlled trial was conducted at King Hussein Medical Hospital (KHMH), one of the Royal Military Medical Services (RMS) tertiary hospitals located in central Amman. During the study period, 128 patients were selected using convenience sampling. Later, medication histories were compared between pre-admission and admission records to obtain the Best Possible Medication History (BPMH) and identify medication discrepancies, which were categorized as either intentional (documentation errors) or unintentional discrepancies.

The already selected patients were randomly allocated into two groups (intervention and control groups). Then, Pharmacist-led medication reconciliation services were provided to the intervention group and standard care was provided to the control group. Also at discharge the number of medication discrepancies was documented. Linear regression analysis was performed to assess risk factors associated with the occurrence of unintentional discrepancies.

Within 30 days post-discharge, patients were assessed for any hospital re-admissions, emergency department visits and medication-related side effects.

Eligibility criteria: Inclusion Criteria:

* Newly admitted patient within no more than 24 hours and anticipated to stay in the hospital for more than 48 hours.
* Geriatrics patients defined as those aged (≥65 years) (Orimo et al., 2006).
* Prescribed at least one chronic medication prior to the study admission.

Exclusion Criteria:

* Patient admitted to the critical care or isolation units or in unconscious or comatose states.
* Patients if they were discharged against medical advice.

Primary outcomes:
measure: Describing prevalence and nature of medication discrepancies in elderly patients and investigating contributing factors to medication discrepancies.
timeFrame: Up to 20 weeks
measure: Analysis of the effects of Pharmacist-led medication reconciliation services on resolving medication discrepancies upon discharge
timeFrame: Up to 16 weeks
measure: Evaluating the impacts of Pharmacist-led medication reconciliation services on hospital re-admissions within 30 days of discharge
timeFrame: Up to 20 weeks
measure: Evaluating the impacts of Pharmacist-led medication reconciliation services on emergency department visits within 30 days of discharge
timeFrame: Up to 20 weeks
measure: Evaluating the impacts of Pharmacist-led medication reconciliation services on medications side effects within 30 days of discharge
timeFrame: Up to 20 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Amman
country: Jordan
facility: University of Jordan
Study officials:
affiliation: Department of Biopharmaceutics and Clinical Pharmacy, School of Pharmacy, University of Jordan
name: Eman A Hammad
role: PRINCIPAL_INVESTIGATOR
References: