Clinical trial NCT00878852: Efficacy of Contingency Management in the Treatment of Adolescents With Cannabis Use Disorders
Official title: Efficacy of a Contingency Management Program in the Treatment of Adolescents With Cannabis Use Disorders in a Child and Adolescent Psychiatry and Psychology Department
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Marijuana Abuse
Lead sponsor: Hospital Clinic of Barcelona
Sponsor class: OTHER
First posted: 2009-04-09
Enrollment: 30
Sex: ALL
Minimum age (years): 12
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Cannabis use among Spanish adolescents has been increasing in the last decade. It has been related to poor school achievement, delinquency, substance use and psychiatric disorders. Furthermore, psychoactive substance use in adolescents presenting psychiatric disorders can result in the development of substance use disorders or the worsening of psychopathology. Thus, there's an urge to develop efficient interventions in the treatment of these disorders. Therapeutic approaches based on cognitive-behavioural therapy and motivational interviewing have demonstrated a limited efficacy in this population. Programs based on contingency management have been reported to be useful both in adult and adolescents, too. But it still remains unclear whether a combination of these therapeutic approaches is feasible and brings a better cost-benefit relation.

The investigators' project aims to evaluate the added benefits of supplementing a standard intervention on cannabis use, based on combined approach that includes motivational and cognitive-behavioural elements, with a contingency management program. Therefore, pre and post-treatment evaluation will be carried forward in a sample of 30 adolescents (aged 12-18) that initiate treatment for cannabis use related disorder at the Child and Adolescent Psychiatry Department of the Hospital Clinic in Barcelona. Participants will be randomly assigned to a standard treatment group or an experimental group in which standard treatment will be supplemented with a contingency management protocol. As a secondary objective, a prospective assessment of neuropsychological performance related to cannabis use or abstinence will be carried forward.


Eligibility criteria: Inclusion Criteria:

* Presence of DSM-IV-TR criteria of cannabis abuse and/or dependence
* Signed informed consent

Exclusion Criteria:

* Mental retardation
* Presence of a substance use disorder other than nicotine or cannabis
* Severe or unstable medical
* Presence at the moment of inclusion of severe acute psychopathology (acute psychotic symptoms, severe depressive symptoms, suicidal ideation)

Primary outcomes:
measure: Percentage of marijuana active users
timeFrame: 12 weeks
Secondary outcomes:
measure: Percentage of negative urine-screens
timeFrame: 12 weeks
measure: Percentage of completed intervention sessions
timeFrame: 12 weeks
measure: Scores in psychopathology and drug scales (T-ASI, SDQ, BDI, Cannabis Problem Questionnaire)
timeFrame: 12 weeks
Other outcomes:
Locations:
city: Barcelona
country: Spain
facility: Hospital Clinic Barcelona
Study officials:
affiliation: Hospital Clinic of Barcelona
name: Javier Goti, M.D
role: PRINCIPAL_INVESTIGATOR
References:
citation: Stephens RS, Babor TF, Kadden R, Miller M; Marijuana Treatment Project Research Group. The Marijuana Treatment Project: rationale, design and participant characteristics. Addiction. 2002 Dec;97 Suppl 1:109-24. doi: 10.1046/j.1360-0443.97.s01.6.x.