Clinical trial NCT04878523: Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions
Official title: Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Skin Condition
Anti Oxidative Stress
Lead sponsor: TCI Co., Ltd.
Sponsor class: INDUSTRY
First posted: 2021-05-07
Enrollment: 40
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: To assess multi berries juice on anti-oxidant effect and skin condition improvement


Eligibility criteria: Inclusion Criteria:

* Healthy adults aged above 20 years old

Exclusion Criteria:

* Subject who is not willing to participate in this study.
* Patients with diseases of the skin, liver, kidney.
* Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
* Female who is pregnant or nursing or planning to become pregnant during the course of the study.
* Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
* Constant drug use

Primary outcomes:
measure: The change of skin UV spots
timeFrame: Change from Baseline skin UV spots at 8 weeks
measure: The change of skin melanin index
timeFrame: Change from Baseline skin melanin index at 8 weeks
measure: The change of blood SOD content
timeFrame: Change from Baseline SOD content at 8 weeks
measure: The change of blood total antioxidant capacity (TAC)
timeFrame: Change from Baseline TAC at 8 weeks
measure: The change of skin L* value
timeFrame: Change from Baseline L* value at 8 weeks
measure: The change of skin spots
timeFrame: Change from Baseline skin spots at 8 weeks
measure: The change of skin brown spots
timeFrame: Change from Baseline skin brown spots at 8 weeks
Secondary outcomes:
measure: The change of skin moisture
timeFrame: Change from Baseline skin moisture at 4 weeks
measure: The change of skin a* value
timeFrame: Change from Baseline a* value at 8 weeks
measure: The change of skin elasticity
timeFrame: Change from Baseline skin elasticity at 8 weeks
measure: The change of skin wrinkles
timeFrame: Change from Baseline skin wrinkles at 8 weeks
measure: The change of skin texture
timeFrame: Change from Baseline skin texture at 8 weeks
measure: The change of skin pores
timeFrame: Change from Baseline skin pores at 8 weeks
measure: The change of skin collagen density
timeFrame: Change from Baseline skin collagen density at 8 weeks
Other outcomes:
measure: The change of total cholesterol of blood
timeFrame: Change from Baseline total cholesterol at 8 weeks
measure: The change of triglyceride of blood
timeFrame: Change from Baseline triglyceride at 8 weeks
measure: The change of SGOT of blood
timeFrame: Change from Baseline SGOT at 8 weeks
measure: The change of SGPT of blood
timeFrame: Change from Baseline SGPT at 8 weeks
measure: The change of BUN of blood
timeFrame: Change from Baseline BUN at 8 weeks
measure: The change of uric acid of blood
timeFrame: Change from Baseline uric acid at 8 weeks
measure: The change of creatinine of blood
timeFrame: Change from Baseline creatinine at 8 weeks
Locations:
city: Tainan City
country: Taiwan
facility: Chia Nan University of Pharmacy & Science
Study officials:
affiliation: Chia Nan University of Pharmacy ＆ Science
name: Chia-Hua Liang
role: PRINCIPAL_INVESTIGATOR
References: