Clinical trial NCT01602744: The Use of STOPP/START Criteria for Medication Intervention Among Elderly Population Living in a Geriatric Hospital
Official title: The Use of STOPP/START Criteria for Medication Intervention and the Risk of Falls, Hospitalization, Functioning and Quality of Life Among Elderly Population Living in a Geriatric Hospital in Israel and Comparison to Beers
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Adverse Drug Effects
Keywords: STOPP screening tool
START screening tool
MIP-medication inappropriate prescription
PIM-Potentially inappropriate medication
Lead sponsor: Wolfson Medical Center
Sponsor class: OTHER_GOV
First posted: 2012-05-21
Enrollment: 382
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SCREENING

Brief summary: The purpose of this study is to determine if the use of STOPP/START criteria (STOPP-screening tool of older persons potentially inappropriate prescriptions START-screening tool to alert doctors to right treatment)for medication intervention in elderly population living in a geriatric hospital will lower the number of falls,hospitalization,will improve functioning, quality of life and reduce financial costs.

Detailed description: Inappropriate prescribing is common in older people and is associated with adverse drug effects,hospitalization and falls. In this trial we want to check the efficacy of the screening tools STOPP/START which were developed and validated in order to reduce inappropriate prescribing. STOPP comprises of 65 indicators of drug-drug, drug-disease interactions and therapeutic duplication. START incorporates 22 evidence based indicators of common prescribing omissions. We will conduct a randomized controlled trial to test the hypothesis that screening the medications of older patients living permanently in a geriatric hospital will improve their quality of life. The compliance of the doctor working in the geriatric hospital to the recommendations of the screening tools will also be checked.

Eligibility criteria: Inclusion Criteria:

* age over 65
* live in the geriatric hospital "Givaat Hashlosha" permanently.

Exclusion Criteria:

* people with a terminal illness that will not live more than a year.
* people who enter the geriatric hospital for a short while (are not permanent).

Primary outcomes:
measure: Quality of Life- Mental Component Summaty (MCS)
timeFrame: Outcome measures were assessed at the end of the 12 month follow up
measure: SF-12 Health Survey questionnaire-the Physical Component Summary (PCS)
timeFrame: Outcome measures were assessed at the end of the 12 month follow up
measure: Falls
timeFrame: At the end of the 12 month follow up
measure: Hospitalizations
timeFrame: Outcome measures were assessed at the end of the 12 month follow up
measure: Functional Independence Measure (FIM)
timeFrame: Outcome measures were assessed at the end of the 12 month follow up
Secondary outcomes:
measure: Pharmacoeconomics Analysis-Costs of Medication
timeFrame: Outcome measures were assessed at the end of the 12 month follow up
Other outcomes:
Locations:
city: Petach Tikva
country: Israel
facility: Givaat Hashlosha Geriatric Hospital
Study officials:
affiliation: Wolfson Medical Center
name: Ariella Herskowits, MBA
role: PRINCIPAL_INVESTIGATOR
References: