Clinical trial NCT06385444: IVF Failure and Pregnancy Loss on Couples' Psychological Stress
Official title: Effects of Implantation Failure and Pregnancy Loss After in Vitro Fertilization on Couples' Psychological Stress
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Fertilization in Vitro
Pregnancy Loss
Psychological Stress
Post-traumatic Stress
Keywords: IVF failure
IVF pregnancy Loss
Psychological Stress
Post-traumatic Stress
Anxiety and depression
Lead sponsor: The First Hospital of Jilin University
Sponsor class: OTHER
First posted: 2024-04-26
Enrollment: 150
Sex: ALL
Minimum age (years): 20
Maximum age (years): 45
Standard ages: ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study was a prospective cohort study. The participants were from couples who underwent in vitro fertilization at the Reproductive Center of the First Hospital of Jilin University.Further questionnaires were conducted for couples with IVF failure and pregnancy loss

Brief summary: The goal of this observational study is to learn about The purpose of this study was to compare the psychological differences between couples after IVF transplant failure and IVF pregnancy loss, including the differences in anxiety, depression, stress and post-traumatic stress between women and their spouses. The main question it aims to answer is:

What are the psychological effects of IVF implantation failure and IVF pregnancy loss on women and the psychological differences between couples? Participants already taking IVF as part of their regular medical care will answer online survey questions about their joint pain for 1 years.

Detailed description: The goal of this observational study is to learn about The purpose of this study was to compare the psychological differences between couples after IVF transplant failure and IVF pregnancy loss, including the differences in anxiety, depression, and stress between women and their spouses. Some couples will experience symptoms of post-traumatic stress reaction (PTS), and there are also large differences. The differences between couples discussed in this study also pay attention to male spouses. Guidance and education for male spouses can reduce cognitive differences between couples and generate understanding and empathy, which is conducive to promoting the stability of family relations and intimate relationships.

1. Does the number of IVF implant failures have a differential effect on anxiety, depression and fertility stress in women and their partners?
2. Does pregnancy loss after IVF transplantation have a differential effect on anxiety, depression, fertility stress and post-traumatic stress responses in women and their partners?

Eligibility criteria: Inclusion Criteria:

1. Couples who have undergone IVF at our center and have completed at least 1 embryo transfer.
2. Female age 20-45 years, male age 22-45 years.

Exclusion Criteria:

1. Couples with contraindications to pregnancy.
2. Couples who undergo donor IVF.
3. Infertility women caused by organic lesions.
4. Couples with previous mental disorders.

Primary outcomes:
measure: As the number of failed IVF implants increases, does it increase the difference in anxiety and depression between couples?
timeFrame: 1 year
measure: As the number of failed IVF implants increases, does it increase the difference in fertility stress between couples?
timeFrame: 1 year
measure: Does pregnancy loss after IVF transplantation have a differential effect on anxiety and depression between couples?
timeFrame: 1 year
measure: Does pregnancy loss after IVF transplantation have a differential effect on post-traumatic stress responses between couples?
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Chang chun
country: China
facility: the first hospital of Jilin University
state: Jilin
Study officials:
affiliation: The First Hospital of Jilin University
name: Qi Xi, doctorate
role: PRINCIPAL_INVESTIGATOR
References:
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