Clinical trial NCT03162692: Preoperative Anxiety's Incidence and Related Factors in Surgical Patients
Official title: Preoperative Anxiety's Incidence and Related Factors in Surgical Patients
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Elective Surgery
Intravenous Anesthesia
Preoperative Anxiety
Lead sponsor: Xuzhou Medical University
Sponsor class: OTHER
First posted: 2017-05-22
Enrollment: 2000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: 2000 patients undergoing elective general anesthesia in surgery in Xuzhou Medical University patients.

Brief summary: Preoperative anxiety is often described as an uncomfortable, tense unpleasant mood before surgery, an emotional response to a potential challenge or threat to reality. Data show that adult patients with preoperative anxiety rate of 30-40%. The main reason for the occurrence of patients for surgery, anesthesia and other factors of fear. Preoperative anxiety itself is not a mental illness, but studies have confirmed that the occurrence of preoperative anxiety and postoperative complications were positively correlated, and the existence of preoperative anxiety in patients with conventional postoperative analgesic effect is poor. At present, there are still few studies on the relationship between preoperative anxiety and postoperative complications and analgesia. At the same time, there is a lack of large sample size to study the incidence of preoperative anxiety and its related predictors.

Detailed description: Surgical patients often have varying degrees of preoperative anxiety.The aim of this study was to determine the incidence of preoperative anxiety and related predictors, and to evaluate the effect of anxiety on anesthesia and postoperative pain and prognosis. The study also showed that prostaglandin, catecholamines, cortex Effects of alcohol and inflammatory cell level on postoperative pain in patients with preoperative anxiety.

Eligibility criteria: Inclusion Criteria:

* Age 18-70 years old
* Sign that informed consent is willing to participate in the study
* Education: primary school and above
* 1 days after elective general anesthesia surgery
* ASA score grade I-III

Exclusion Criteria:

* Emergency surgery
* Severe mental illness patients (such as anxiety, depression, schizophrenia, etc.)
* Taking anti-anxiety or antidepressants (benzodiazepines, tricyclic antidepressants, selective serotonin inhibitors, monoamine oxidase inhibitors, etc.)

Primary outcomes:
measure: Anxiety level
timeFrame: All patients are evaluated one day before surgery
Secondary outcomes:
measure: VAS pain score
timeFrame: at 3 hours, 6 hours, 24 hours, 48 hours after surgery
Other outcomes:
measure: blood inflammation index
timeFrame: Extraction of arterial blood before anesthesia induction
Locations:
city: XuZhou
country: China
facility: The Affiliated Hospital of Xuzhou Medical University
state: Jiangsu
Study officials:
affiliation: The Affiliated Hospital of Xuzhou Medical University
name: Jindong Liu, M.S
role: PRINCIPAL_INVESTIGATOR
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