Clinical trial NCT04444037: Impact of OCT Imaging on Decision Making During PCI in ACS Patients
Official title: Impact of Optical Coherence Tomography Imaging on Decision-making During Percutaneous Coronary Intervention in Patients Presented With Acute Coronary Syndromes
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Acute Coronary Syndrome
Keywords: OCT, stent implantation
Lead sponsor: Assiut University
Sponsor class: OTHER
Collaborators: name: Wakayama Medical University
First posted: 2020-06-23
Enrollment: 390
Sex: ALL
Minimum age (years): 16
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient either underwent PCI with angiography alone or OCT guided and is grouped accordingly

Brief summary: Optical coherence tomography (OCT) provides valuable information to guide percutaneous coronary intervention (PCI) in acute coronary syndrome (ACS) regarding lesion preparation, stent sizing, and stent optimization.

Detailed description: OCT can be used in acute coronary syndrome (ACS). ACS has more complex culprit lesion morphologies and larger extent of coronary atherosclerosis compared with stable coronary artery disease. The detailed vascular information obtained by OCT may impact PCI in ACS, and which may improve acute results and late outcomes of PCI. Stent expansion immediately after PCI is a strong predictor of late outcomes of PCI, and it is associated with late clinical outcomes in many previous trials.

Eligibility criteria: Inclusion Criteria:

* Patients presented with acute coronary syndrome.
* PCI was done to them with stent implantation.

Exclusion Criteria:

* Multivessel PCI at the index procedure.
* Patients with ACS due to graft failure post CABG.
* Patients treated with no stent implantation.

Primary outcomes:
measure: Percent difference in lumen expansion in stent treated lesion
timeFrame: Immediately after the procedure
Secondary outcomes:
measure: Clinical outcomes at 1 year follow up
timeFrame: During 1 year following the index procedure
Other outcomes:
Locations:
city: Wakayama
country: Japan
facility: Wakayama Medical University
Study officials:
affiliation: Assiut University
name: Yehia T Kishk, MD
role: STUDY_CHAIR
affiliation: Assiut University
name: Hossam H Ali, MD
role: STUDY_CHAIR
affiliation: Assiut University
name: Ahmed Abdel-Galeel, MD
role: STUDY_CHAIR
affiliation: Wakayama Medical University
name: Takashi Akasaka, MD, PhD
role: STUDY_CHAIR
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