Clinical trial NCT01497080: Distal Radius Fracture Prospective Database 50-80 Years Old
Official title: Distal Radius Fracture Prospective Database 50-80 Years Old Overview: "Identification of Risk of Adverse Activity Transition Following a Distal Radius Fracture".
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Radius Fracture Distal
Keywords: distal radius fracture
Condition
risk factors
adverse activity transitions following DRF
optimal assessment approach
Lead sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sponsor class: OTHER
First posted: 2011-12-22
Enrollment: 195
Sex: ALL
Minimum age (years): 50
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Participants aged 50-80 years of age who have incurred a wrist fracture

Brief summary: The Problem Distal radius fractures (DRF) are common and result in a variable amount of disability. The investigators have completed considerable work in developing tools that measure impairment and disability after DRF . The investigators initial studies indicate that the associated disablement process is multifactorial and variable with only 25% of the resultant disability predicted by baseline patient and injury characteristics. The investigators see DRF as a signal event where some people are at-risk of transitioning from an active lifestyle to inactivity and subsequent health risks. The investigators recent data confirms variable participation following a DRF. The traditional focus in orthopedic/rehabilitative approaches to DRF fracture management has been localized to the wrist, largely ignoring this potential transition and its health impacts. The investigators will initiate a line of investigation that will profile the at-risk older adult who presents with a DRF with the ultimate goal of accurate identification and prevention of adverse activity transitions (active to inactive). In this study the investigators will identify the extent of the problem by quantifying changes in activity/participation and its short-term health impacts. The investigators will also identify the risk factors present at time of injury that predict a loss of mobility/activity/participation. This work has the potential to identify tools and/or clinical prediction rules that identify at-risk individuals at a critical time where early intervention might most easily prevent adverse outcomes associated with inactivity.


Eligibility criteria: Inclusion Criteria:

individuals 50-80 years old

* one month of fracture resulting from a fall from standing height or less will be recruited through our orthopedic surgeon
* wrist fracture

Exclusion Criteria:

previous history of humeral, hip or vertebral fracture

• Testing will not be performed on patients with evident postural instability, severe chronic conditions (Parkinson's disease) or other vestibulo-ocular abnormalities.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: London
country: Canada
facility: HULC, St Joseph's health Care London
state: Ontario
Study officials:
affiliation: St. Joseph's Health Care London
name: Joy MacDernmid, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Colquhoun HL, Letts LJ, Law MC, MacDermid JC, Missiuna CA. A scoping review of the use of theory in studies of knowledge translation. Can J Occup Ther. 2010 Dec;77(5):270-9. doi: 10.2182/cjot.2010.77.5.3.
citation: Grewal R, MacDermid JC, Pope J, Chesworth BM. Baseline predictors of pain and disability one year following extra-articular distal radius fractures. Hand (N Y). 2007 Sep;2(3):104-11. doi: 10.1007/s11552-007-9030-x. Epub 2007 Mar 23.