Clinical trial NCT04458480: Effect of Fast Inpatient Rehabilitation After TKA
Official title: Effect of Fast Inpatient Rehabilitation After Total Knee Arthroplasty
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Total Knee Arthroplasty
Rehabilitation
Keywords: Fast Rehabilitation
Inpatient Rehabilitation
Total Knee Arthroplasty
Lead sponsor: Peking University Third Hospital
Sponsor class: OTHER
First posted: 2020-07-07
Enrollment: 60
Sex: ALL
Minimum age (years): 50
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: He/She is admitted to orthopedics department of Peking University Third Hospital and undertaken initial unilateral TKA due to osteoarthritis, rheumatoid arthritis, etc.

Brief summary: Rehabilitation is an important part of the post-operative treatment after TKA by consensus. This study intends to analysis whether fast inpatient rehabilitation after TKA can improve knee joint or general function, and ultimately explore for effects and values of fast inpatient rehabilitation after TKA.

Detailed description: Rehabilitation, which is an important part of the post-operative treatment after TKA, could effectively alleviate symptoms of pain and swell, as well as improve knee joint and general function. It has reached a consensus that post-TKA rehabilitation should contain muscle strengthening, ROM, proprioceptive, balance training and physical factor therapy, etc. This study intends to use observational cohort study methods with exposure factor of fast inpatient rehabilitation after TKA, establish a TKA exposure group and a control group of TKA without inpatient rehabilitation, analysis whether fast inpatient rehabilitation after TKA can improve knee joint or general function, and ultimately explore for effects and values of fast inpatient rehabilitation after TKA.

Eligibility criteria: Inclusion Criteria:

* Initial unilateral TKA patients due to osteoarthritis, rheumatoid arthritis, etc.
* Satisfactory operative knee joint ROM: knee flexion ≥120° and extension ≥ 0°.
* Prior informed consent by patients.

Exclusion Criteria:

* Complication of other medical conditions and disability to cooperate with rehabilitation.
* Complication of other conditions affecting bilateral lower limbs such as fracture, tumor, neurologic disorder, etc.
* Deep venous thrombosis of lower limbs with exception of inter-muscular venous thrombosis.

Primary outcomes:
measure: bilateral knee Rang Of Motion (ROM)
timeFrame: 1 day after TKA
measure: bilateral quadriceps femurs
timeFrame: 1 day after TKA
measure: hamstrings muscle strength
timeFrame: 1 day after TKA
measure: Hospital for Special Surgery-Knee Rating scale (HSSKR)
timeFrame: 1 day after TKA
measure: modified Barthel Index (mBI)
timeFrame: 1 day after TKA
measure: Numerical Rating Scale (NRS) for pain
timeFrame: 1 day after TKA
measure: NRS for pain
timeFrame: 6 weeks after TKA
measure: NRS for pain
timeFrame: 3 months after TKA
measure: NRS for pain
timeFrame: 6 months after TKA
measure: Knee Injury and Osteoarthritis Outcome Score (KOOS)
timeFrame: 1 day after TKA
measure: KOOS
timeFrame: 6 weeks after TKA
measure: KOOS
timeFrame: 3 months after TKA
measure: KOOS
timeFrame: 6 months after TKA
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Peking University Third Hospital
state: Beijing
Study officials:
affiliation: Peking University Third Hospital
name: Mouwang Zhou, MM
role: STUDY_CHAIR
References: