Clinical trial NCT05839236: COVID-19 Vaccination Detoxification in LDL-C
Official title: COVID-19 Vaccination Detoxication in Low Density Lipoprotein Cholesterol
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE1
Conditions: COVID-19 Stress Syndrome
COVID-19 Vaccine Adverse Reaction
COVID-19-Associated Thromboembolism
COVID-19 Post-Intensive Care Syndrome
COVID-19-Associated Stroke
COVID-19 Respiratory Infection
Keywords: COVID-19
SARS-CoV-2
Low Density Lipoprotein Cholesterol
sebum
immune reflex
immunology
immune deficiency
immune regulation
detoxification
Lead sponsor: Pachankis, Yang I., M.D.
Sponsor class: INDIV
First posted: 2023-05-03
Enrollment: 1
Sex: MALE
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SEQUENTIAL
Primary purpose: TREATMENT

Brief summary: The study hypothesizes that SARS-CoV-2 vaccination poisoning hibernates in human host in Low Density Lipoprotein Cholesterol (LDL-C). The clinical trial is a follow-up from the intervention trial with NCT number NCT05711810. It tests the use of Atorvastatin Calcium Tablets for detoxification and prevention of blood acidification, and the use of the Chinese herb compounded Anti-Viral Granules for the detoxification in the endocrine system.


Eligibility criteria: Inclusion Criteria:

* People who received COVID-19 vaccinations, or experiencing long-COVID.

Exclusion Criteria:

* People with moderate and severe liver dysfunctions.

Primary outcomes:
measure: Total Cholesterol Change
timeFrame: 30 days
measure: Triglycerides Change
timeFrame: 30 days
measure: HDL-C Change
timeFrame: 30 days
measure: LDL-C Change
timeFrame: 30 days
measure: Apolipoprotein A-I Change
timeFrame: 30 days
measure: Apolipoproteina B Change
timeFrame: 30 days
measure: Lipopoliproteina (a) Change
timeFrame: 30 days
measure: Eosinophil Absolute Number Change
timeFrame: 30 days
measure: Eosinophil Percentage Change
timeFrame: 30 days
measure: Basophil Absolute Number Change
timeFrame: 30 days
measure: Basophil Percentage Change
timeFrame: 30 days
measure: Mean Corpuscular Volume Change
timeFrame: 30 days
measure: Mean Corpuscular Hemoglobin Change
timeFrame: 30 days
measure: Mean Corpuscular Hemoglobin Concentration Change
timeFrame: 30 days
measure: Red cell Distribution Width Coefficient of Variation Change
timeFrame: 30 days
measure: Red cell Distribution Width Standard Deviation Change
timeFrame: 30 days
measure: Plateletcrit Change
timeFrame: 30 days
measure: Platelet Distribution Width Change
timeFrame: 30 days
measure: Mean Platelet Volume Change
timeFrame: 30 days
Secondary outcomes:
measure: Heart Rate Change
timeFrame: 4 hours
measure: Systolic Blood Pressure Change
timeFrame: 4 hours
measure: Diastolic Blood Pressure Change
timeFrame: 4 hours
Other outcomes:
Locations:
city: Chongqing
country: China
facility: Residential Address
state: Chongqing
Study officials:
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