Clinical trial NCT04818307: Mulligan Mobilization With Movement Versus Macquarie Injury Management Group in Function and Pain of Knee Osteoarthritis
Official title: Long Term Effects of Mulligan Mobilization With Movement Versus Macquarie Injury Management Group on Function and Pain of Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Knee Pain
Movement with Mobilization
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-03-26
Enrollment: 26
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Knee pain is one of the most usual pain that commonly affects people especially in the late age. It can be caused by osteoarthritis, poor posture or sitting position, bad bending or improper lifting. It is usually not caused by a serious illness. It is the most common cause of disability. To compare the long term effects of Mulligan Mobilization with Movement versus Macquarie Injury Management Group on pain and function of knee osteoarthritis.

Detailed description: It was a randomized clinical trial conducted in Revival Physiotherapy Center, Lahore. A convenient sample of 26 diagnosed patients with osteoarthritis was included in the study. Subjects were randomly distributed in to two groups with use of flip coin method Group of randomization. Group 1 patients got MIMG with routine physical therapy and Group 2 got MWM with routine physical therapy. Visual analogue Scale (VAS),Non modified WOMAC were used to assess all patients before and after 4 weeks of intervention. Statistical analysis was computed by SPSS 20.0.

Eligibility criteria: Inclusion Criteria:

* ACR criteria for knee will be over age 50
* less than 30 minutes of morning stiffness,
* Crepitus on active motion,
* Tenderness
* Enlargement
* No palpable warmth of synovium.
* Osteoarthritis grade 1 and 2 by Kelly-green and Lawrence method.

Exclusion Criteria:

* Any surgical procedure done in past 6 months and metal implants in lower extremity.
* Any infection and neoplastic disorder.
* Post traumatic knee stiffness.
* Secondary knee O A peripheral vascular disease

Primary outcomes:
measure: Visual Analogue scale
timeFrame: 6 months
measure: WOMAC
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Riphah Rehabilitation Center
state: Punjab
Study officials:
affiliation: Riphah International University
name: Maryam Shabbir
role: PRINCIPAL_INVESTIGATOR
References:
citation: Kandada S, Heggannavar A. Effect of Mulligan's MWM versus Macquarie Injury Management Group (MIMG) protocol on pain and function in osteoarthritis of knee: a randomised clinical trial. IJTRR. 2015;4(4):125-31.
citation: Bhatia D, Bejarano T, Novo M. Current interventions in the management of knee osteoarthritis. J Pharm Bioallied Sci. 2013 Jan;5(1):30-8. doi: 10.4103/0975-7406.106561.
citation: Felson DT. The epidemiology of knee osteoarthritis: results from the Framingham Osteoarthritis Study. Semin Arthritis Rheum. 1990 Dec;20(3 Suppl 1):42-50. doi: 10.1016/0049-0172(90)90046-i.
citation: Felson DT, Gale DR, Elon Gale M, Niu J, Hunter DJ, Goggins J, Lavalley MP. Osteophytes and progression of knee osteoarthritis. Rheumatology (Oxford). 2005 Jan;44(1):100-4. doi: 10.1093/rheumatology/keh411. Epub 2004 Sep 20.
citation: Cooper C, McAlindon T, Coggon D, Egger P, Dieppe P. Occupational activity and osteoarthritis of the knee. Ann Rheum Dis. 1994 Feb;53(2):90-3. doi: 10.1136/ard.53.2.90.
citation: Alshami AM. Knee osteoarthritis related pain: a narrative review of diagnosis and treatment. Int J Health Sci (Qassim). 2014 Jan;8(1):85-104. doi: 10.12816/0006075.