Clinical trial NCT05638178: The Corona Study of Middle Norway
Official title: The Middle Norway Corona Study - Individual and Genetic Risk Factors for COVID-19 Infection.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: SARS-CoV-2 Acute Respiratory Disease
SARS-CoV-2 Sepsis
SARS CoV 2 Infection
Lead sponsor: St. Olavs Hospital
Sponsor class: OTHER
Collaborators: name: The Research Council of Norway
name: Alesund Hospital
name: Namsos Hospital
name: Molde Hospital
name: Helse Nord-Trøndelag HF
First posted: 2022-12-06
Enrollment: 223
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Population of Middle Norway Health Region

Brief summary: CUT COVID is a cohort study establised to collect information on patients hospitalized because or with infection by SARS-CoV-2. The cohort data includes clinical data and biological samples from multiple timepoints during hospitalization, as well as data from a followup consultation 3 months after discharge.


Eligibility criteria: Inclusion Criteria:

* Positive SARS CoV-2 infection

Exclusion Criteria:

-

Primary outcomes:
measure: Predictors of COVID-19 severity
timeFrame: 1 year after inclusion.
Secondary outcomes:
Other outcomes:
Locations:
city: Trondheim
country: Norway
facility: St. Olavs Hospital
state: MN
city: Molde
country: Norway
facility: Molde Hospital
state: MR
city: Ålesund
country: Norway
facility: Ålesund Hospital
state: MR
city: Levanger
country: Norway
facility: Levanger Hospital
state: NT
city: Namsos
country: Norway
facility: Namsos Hospital
state: NT
Study officials:
affiliation: St. Olavs Hospital
name: Kari Risnes, MD/PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Ponsford MJ, Gkatzionis A, Walker VM, Grant AJ, Wootton RE, Moore LSP, Fatumo S, Mason AM, Zuber V, Willer C, Rasheed H, Brumpton B, Hveem K, Kristian Damas J, Davies N, Asvold BO, Solligard E, Jones S, Burgess S, Rogne T, Gill D. Cardiometabolic Traits, Sepsis, and Severe COVID-19: A Mendelian Randomization Investigation. Circulation. 2020 Nov 3;142(18):1791-1793. doi: 10.1161/CIRCULATIONAHA.120.050753. Epub 2020 Sep 23. No abstract available.
citation: COVID-19 Host Genetics Initiative. Mapping the human genetic architecture of COVID-19. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8.
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