Clinical trial NCT06038500: Multicomponent Intervention in Women at Risk of Sarcopenia
Official title: Effect of an Intervention of Dance, Resistance Exercises and Nutritional Recommendations on Muscle Mass and Strength in Women With Risk of Sarcopenia
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Sarcopenia
Grip Strength
Gait Speed
Body Composition
Keywords: Sarcopenia
Multicomponent
Aging
Preventive
Lead sponsor: Coordinación de Investigación en Salud, Mexico
Sponsor class: OTHER_GOV
Collaborators: name: University of Guadalajara
name: Universidad de Colima
First posted: 2023-09-14
Enrollment: 14
Sex: FEMALE
Minimum age (years): 55
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: quasi-experimental Pre-test/Post-test design - pilot
Primary purpose: PREVENTION

Brief summary: The goal of this quasi-experimental pilot study is to evaluate the effect of a multi-component intervention in women between 55 and 75 years old at risk of sarcopenia. The main question it aims to answer are: What is the effect of a multi-component intervention in women at risk of sarcopenia? Participants will twelve women between 55 and 75 years old with risk of sarcopenia, who agreed through written informed consent for participate 12 weeks with 24 sessions included dancing, resistance exercises, and nutritional education. The outcomes were muscle mass, grip strength, gait speed and body composition. The effects were measured before and after the intervention, under a self-controlled design.

Detailed description: Physical exercise, especially resistance exercise, is one of the best non-pharmacological treatment alternatives due to its multiple health benefits and could be a promoter for the prevention of sarcopenia by delaying muscle atrophy produced by the natural aging process. However, scientific literature shows that this activity when combined with other strategies has a better effect on sarcopenia indicators than alone. Dance is a social activity that is part of the culture and life history of human beings, however, current research has focused on studying the cognitive and visuospatial effects of this activity. It could be an activity with beneficial effects on the physical abilities of the individual since dancing improves flexibility, resistance and balance. However, the study of these two strategies, along with nutritional education has been little studied.

Therefore, a pilot test was proposed with the aim of knowing the possible effect of a multicomponent intervention on muscle, strength, performance, and body composition on women at risk of sarcopenia.

Eligibility criteria: Inclusion Criteria:

* Positive requested through written informed consent
* Current public health insurance
* Preserved physical and mental capacities (verified through data from the medical record)
* Having a lower grip strength, less or equal to 20.99 kg
* Appendicular skeletal muscle index (ASMI) maintained, greater or equal to 5.5 kg/m\^2
* Walking speed greater or equal to 0.8 m/s

Exclusion Criteria:

* Bioelectric activity add (osteosynthesis metal systems or devices, pacemakers, defibrillators)
* Alterations of body composition (history of cancer, uncontrolled chronic degenerative diseases, risk of malnutrition, respiratory insufficiency, asthma or chronic obstructive pulmonary disease, hospitalization in the year prior to the study; limitations in carrying out the basic activities of daily living; medical contraindication for physical activity, and or belonging to another physical activity group).

Primary outcomes:
measure: Grip strength
timeFrame: Baseline measurement and final measurement as the end of the 12 weeks of intervention
measure: Skeletal muscle mass index (SMI)
timeFrame: Baseline measurement and final measurement as the end of the 12 weeks of intervention
measure: Gait speed
timeFrame: Baseline measurement and final measurement as the end of the 12 weeks of intervention
Secondary outcomes:
measure: Anthropometric measurements
timeFrame: Baseline measurement and final measurement as the end of the 12 weeks of intervention
Other outcomes:
measure: Polypharmacy report (yes/no)
timeFrame: Baseline measurement
measure: Comorbidity
timeFrame: Baseline measurement
Locations:
city: Guadalajara
country: Mexico
facility: Maria Claudia Espinel-Bermudez
state: Jalisco
Study officials:
References: