Clinical trial NCT05581680: Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects
Official title: Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Electromyography
Eye-tracking
Facial Palsy
Keywords: facial mimics
motion capture
electromyography
eye-tracking
Facial Palsy
Lead sponsor: Centre Hospitalier Universitaire, Amiens
Sponsor class: OTHER
First posted: 2022-10-14
Enrollment: 720
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials. The proposed treatments are based on surgery, physiotherapy and botulinum toxin injections. However, when recovery is incomplete, acceptance is more difficult, with an impacted quality of life. Thanks to Motion Capture and Electromyography, a quantification of the facial mimicry is now possible with a great precision. In addition with the quantification of the facial mimicry, eye-tracking, wich is widely used in the marketing field, but it also finds medical applications including head and neck lesions and facial palsy in particular, will be used to evaluate the visio of the patients on their pathology in function of the movement quantification measured with MoCap and Electromyography. The aim of this research is to measure in a combined way the action potentials by sEMG and the amplitudes of displacement of the markers in motion capture, for movements determined in a population of patients presenting a facial pathology, in order to compare them with reference values obtained in healthy subjects. In a second step, the aim will be to study if there is a link between the way the patient looks at his pathology and the results of his management (treatment, rehabilitation) which will be quantitatively evaluated thanks to MoCap and sEMG.


Eligibility criteria: Inclusion Criteria:

* Subjects with no known facial pathology (healthy volunteers) OR
* Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated
* Subject with written informed consent
* Subject over 18 years of age
* Subject affiliated to a social security scheme

Exclusion Criteria:

* Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers
* Subjects with speech disorders making it impossible to pronounce the sounds \[o\] and \[pu\]
* Subject unable to provide written informed consent
* Subjects under guardianship, curators or safeguard of justice

Primary outcomes:
measure: determination of baseline values of facial mimicry (in millimetres) in healthy volunteers
timeFrame: one month
measure: determination of baseline values of eye-tracking (in millimetres) in healthy volunteers
timeFrame: one month
measure: determination of the maximum range of motion of facial mimicry (in millimetres) in patients
timeFrame: one year
measure: determination of the maximum range of motion of eye-tracking (in millimetres) in patients
timeFrame: one year
Secondary outcomes:
Other outcomes:
Locations:
city: Amiens
country: France
facility: CHU Amiens Picardie
state: Picardie
Study officials:
References: