Clinical trial NCT01287429: Lung Ultrasound for Acute Dyspnea in Emergency Department
Official title: Lung Ultrasound for Acute Dyspnea in Emergency Department - Prospective Multicenter Study on Accuracy, Reproducibility, and Diagnostic Impact of Lung Ultrasound in the Evaluation of Patients With Dyspnea in the Emergency Department
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Dyspnea
Congestive Heart Failure
Keywords: Ultrasonography
Lead sponsor: University of Turin, Italy
Sponsor class: OTHER
Collaborators: name: Azienda Ospedaliera San Giovanni Battista
name: San Luigi Gonzaga Hospital
name: Agnelli Hospital, Italy
name: Azienda Ospedaliera Ordine Mauriziano di Torino
name: Martini Hospital, Turin, Italy
name: Ospedale Cardinal Massaia
name: Ospedale Santa Croce-Carle Cuneo
First posted: 2011-02-01
Enrollment: 1005
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Hospital Emergency Departments sample

Brief summary: Dyspnea is a frequent symptom in patients admitted to the Emergency Department (ED); discriminating between cardiogenic and non-cardiogenic dyspnea is a common clinical dilemma. The initial diagnostic work-out is often not very accurate in defining the etiology and the underlying pathophysiology. In the last years, lung ultrasound (US) has emerged as a useful real-time bedside diagnostic tool in the critical patient. The aim of this study was to evaluate the accuracy, reproducibility, and diagnostic impact of pleural and lung US, performed by emergency physicians at the time of patient first presentation to the ED, in identifying cardiac causes of acute dyspnea.


Eligibility criteria: Inclusion Criteria:

* Patients had to present to the ED with a principal complaint of shortness of breath, deﬁned as either the sudden onset of dyspnea with no history of chronic dyspnea or an increase in the severity of chronic dyspnea in the last 48 hours;
* Presence of an emergency physician with lung US experience at the time of enrollment;
* US examination within 30 minutes after the start of the clinical evaluation.

Exclusion Criteria:

* Dyspnea cases clearly due to neither cardiogenic nor respiratory etiology will considered not eligible.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Asti
country: Italy
facility: Emergency Medicine & Surgery Unit - Cardinal Massaia Hospital
city: Cuneo
country: Italy
facility: Emergency Department - AO Santa Croce e Carle
city: Orbassano
country: Italy
facility: Emergency Medicine Unit - AOU San Luigi Gonzaga
city: Pinerolo
country: Italy
facility: Emergency Medicine & Surgery Unit - Pinerolo General Hospital, ASL TO 3
city: Turin
country: Italy
facility: Emergency Department - AOU San Giovanni Battista
city: Turin
country: Italy
facility: Emergency Medicine and Surgery Unit- AO Mauriziano
city: Turin
country: Italy
facility: Emergency Medicine & Surgery Unit - Martini Hospital, ASL TO 2
Study officials:
affiliation: Cancer Epidemiology Unit - University of Turin
name: Emanuele Pivetta
role: PRINCIPAL_INVESTIGATOR
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