Clinical trial NCT04805580: Qudratus Lumborum Block Versus Unilateral Intrathecal Block for Inguinal Hernia Repair
Official title: Ultrasound Guided Qudratus Lumborum Block Versus Unilateral Intrathecal Block for Patient Undergoing Inguinal Hernia Repair
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Inguinal Hernia,Quadratus Lumborum Block , Unilateral Intrathecal Block
Lead sponsor: Zagazig University
Sponsor class: OTHER_GOV
First posted: 2021-03-18
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: 2 groups (25 in each group) group intrathecal block group quadratus lumborum block
Primary purpose: TREATMENT

Brief summary: compare between Quadratus lumborum block and unilateral intrathecal block for patients undergoing inguinal hernia repair regarding the quality of anesthesia and hemodynamic stability of patients.

Detailed description: comparison between unilateral intrathecal block anesthesia (unilateral SA) and Quadratus lumborum block for inguinal hernia repair unilateral intrathecal block is widely used nowadays for unilateral inguinal hernia repair, providing intense sensory and motor blockade. Limiting the block to the operative site by using small doses of hyperbaric solutions injected slowly through a directional needle and maintaining a lateral decubitus position for a certain duration has been proposed, to produce high quality, long-duration analgesia, with minimal hemodynamic adverse events.

Previous case report studies stated that we can use Quadratus Lumborum Block as the sole anesthetic technique for open hernia repair.

Eligibility criteria: Inclusion Criteria:

- physical status ASA: I-II BMI \>18kg/m2\<30kg/m2 written informed consent from the patient scheduled for open unilateral inguinal hernia repair

Exclusion Criteria:

* uncooperative patient
* Allergy to local anesthetic drugs
* patients on chronic alcohol, opioid, tranquilizer or sedative use
* Pregnant females.
* Psychological, mental disorders, or depression.
* Patients receiving anticoagulants therapy or suspected coagulopathy.
* Patients with infection or previous surgery at sit of anesthetic procedures.
* Patients with significant cardiovascular, respiratory, renal, hepatic, or metabolic disease

Primary outcomes:
measure: To assess safety of quadratus lumborum block vs unilateral intrathecal block for inguinal hernia repair: complications of the block
timeFrame: 2 hours
Secondary outcomes:
measure: To compare the onset and duration of sensory block between both blocks
timeFrame: 12 hours
measure: To compare the time to ambulation
timeFrame: 24 hours
Other outcomes:
Locations:
Study officials:
References:
citation: Favaro ML, Gabor S, Souza DBF, Araujo AA, Milani ALC, Ribeiro Junior MAF. Quadratus Lumborum Block As A Single Anesthetic Method For Laparoscopic Totally Extraperitoneal (Tep) Inguinal Hernia Repair: A Randomized Clinical Trial. Sci Rep. 2020 May 22;10(1):8526. doi: 10.1038/s41598-020-65604-x.
citation: La Colla L, La Colla MDL, Schroeder R, Schroeder RMD. Quadratus Lumborum Block as Sole, Homeostatic-Preserving Anesthetic for a Patient with Multiple System Atrophy Undergoing Open Inguinal Hernia Repair: A Case Report. Case Rep Anesthesiol. 2018 Jun 28;2018:7161860. doi: 10.1155/2018/7161860. eCollection 2018.
citation: Isil CT, Cinar AS, Oba S, Isil RG. Comparison of Spinal Anaesthesia and Paravertebral Block in Unilateral Inguinal Hernia Repair. Turk J Anaesthesiol Reanim. 2014 Oct;42(5):257-63. doi: 10.5152/TJAR.2014.75508. Epub 2014 Jul 9.