Clinical trial NCT02087137: Functional Impact of a Memory Intervention Program
Official title: Functional Impact of a Memory Intervention Program
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Aging
Keywords: aging
memory
memory training
Lead sponsor: Baycrest
Sponsor class: OTHER
First posted: 2014-03-14
Enrollment: 69
Sex: ALL
Minimum age (years): 50
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Normal aging is associated with decline in some aspects of memory, and this can be a risk factor for reductions in everyday functioning. The Baycrest Memory and Aging Program teaches positive adaptation to age-related memory changes, including strategies for minimizing the everyday impact of normal memory change and positive lifestyle change to maximize brain health. Prior research has shown that the Memory and Aging program is effective in increasing participants' knowledge about memory, use of memory strategies, and confidence in memory function, as well as adoption of healthier lifestyle practices and reduction in intention to use unneeded health care resources.

Although not one of the stated goals of the program, informal feedback from participants suggests that the educational content and skills training in the Memory and Aging Program has led some participants to change behaviours in ways that lead to significant improvements in their everyday functioning. For example, graduating participants often volunteer examples of how they have applied what they have learned to succeed in everyday memory tasks such as learning a new name or keeping track of future plans. Based on this participant feedback, it is hypothesized that the knowledge, skills, and confidence gained by Memory and Aging Program participants may lead to positive behaviour changes that, in turn, lead to improved everyday functioning. The present study will test this hypothesis using a randomized controlled pretest-posttest design.


Eligibility criteria: Inclusion Criteria:

* Age 50-90
* Available to participate in all testing and intervention sessions (located in Toronto, Canada)

Exclusion Criteria:

* health conditions with major effects on cognition, including a current or previous history of stroke, brain surgery, or diagnosed neurological disorder
* dependence in instrumental activities of daily living
* cognitive impairment, defined as performance below cutoff for cognitive impairment on a standardized cognitive test, the Telephone Interview for Cognitive Status (Brandt, Spencer, \& Folstein, 1988).
* affective impairment, defined as performance below cutoff for depression on standardized depression screen, the Geriatric Depression Scale (Yesavage et al., 1983)

Primary outcomes:
measure: Change from baseline in healthy lifestyle behaviours as measured by Health Promoting Lifestyle Profile II (Walker, Sechrist, & Pender, 1987)
timeFrame: Baseline, Week 8, week 14
measure: Change from baseline in memory strategy use as measured by the Memory Strategy Toolbox (modified from Troyer, 2001)
timeFrame: Baseline, Week 8, week 14
measure: Attainment of individualized goals for (a) lifestyle change, (b) memory strategy use, and (c) functional outcomes of memory strategy use as measured by Goal Attainment Scaling (Gordon, Powell, & Rockwood, 2000; Kiresuk, Smith, & Cardillo, 1994)
timeFrame: Baseline, Week 8, week 14
Secondary outcomes:
measure: Change in positive and negative affect as measured by Positive and Negative Affect Schedule (Watson, Clark, & Tellegen, 1988)
timeFrame: Baseline, Week 8, week 14
measure: Change in general health status as measured by the RAND 36-Item Short-Form Health Survey (Ware & Sherbourne, 1992).
timeFrame: Baseline, Week 8, week 14
measure: General Self-Efficacy Scale (Schwarzer & Jerusalem, 1995)
timeFrame: Baseline, Week 8, week 14
measure: Prospective and Retrospective Memory Questionnaire (Smith, Della Sala, Logie, & Maylor, 2000)
timeFrame: Baseline, Week 8, week 14
measure: Self-report health status, lifestyle changes, attitudes about aging
timeFrame: Baseline, Week 8, week 14
Other outcomes:
measure: Change in memory knowledge as measured by Memory knowledge quiz (modified from Troyer, 2001).
timeFrame: Baseline, Week 8, week 14
measure: Change in self-perceived memory as measured by Multifactorial Metamemory Questionnaire (Troyer & Rich, 2002)
timeFrame: Baseline, 8 weeks, 14 weeks
measure: Change in prospective memory function (Prospective telephone-call task, Troyer, 2001; actual week, Rendell & Craik, 2001)
timeFrame: Baseline, 8 weeks, 14 weeks
measure: Change in name learning (Name-learning task, based on Troyer, Häfliger, Cadieux, & Craik, 2006)
timeFrame: Baseline, 8 weeks, 14 weeks
Locations:
city: Toronto
country: Canada
facility: Baycrest
state: Ontario
Study officials:
affiliation: Baycrest
name: Susan Vandermorris, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Brandt, J., Spencer, M., & Folstein, M. (1988). The Telephone Interview for Cognitive Status. Neuropsychiatry, Neuropsychology, & Behavioral Neurology, 1(2), 111-117.
citation: Gordon J, Rockwood K, Powell C. Assessing patients' views of clinical changes. JAMA. 2000 Apr 12;283(14):1824-5. No abstract available.
citation: Kiresuk, T. J., Smith, A., & Cardillo, J. E. (1994). Goal attainment scaling: Applications, theory, and measurement. Hillsdale, NJ: Lawrence Erlbaum Associates.
citation: Troyer, A. K. (2001). Improving memory knowledge, satisfaction, and functioning via an education and intervention program for older adults. Aging, Neuropsychology, and Cognition, 8(4), 256-268.
citation: Troyer AK, Hafliger A, Cadieux MJ, Craik FI. Name and face learning in older adults: effects of level of processing, self-generation, and intention to learn. J Gerontol B Psychol Sci Soc Sci. 2006 Mar;61(2):P67-74. doi: 10.1093/geronb/61.2.p67.
citation: Troyer AK, Rich JB. Psychometric properties of a new metamemory questionnaire for older adults. J Gerontol B Psychol Sci Soc Sci. 2002 Jan;57(1):P19-27. doi: 10.1093/geronb/57.1.p19.
citation: Walker SN, Sechrist KR, Pender NJ. The Health-Promoting Lifestyle Profile: development and psychometric characteristics. Nurs Res. 1987 Mar-Apr;36(2):76-81.
citation: Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992 Jun;30(6):473-83.
citation: Watson D, Clark LA, Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J Pers Soc Psychol. 1988 Jun;54(6):1063-70. doi: 10.1037//0022-3514.54.6.1063.
citation: Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982-1983;17(1):37-49. doi: 10.1016/0022-3956(82)90033-4.
citation: Vandermorris S, Au A, Gardner S, Troyer AK. Initiation and maintenance of behaviour change to support memory and brain health in older adults: A randomized controlled trial. Neuropsychol Rehabil. 2022 May;32(4):611-628. doi: 10.1080/09602011.2020.1841656. Epub 2020 Nov 17.
citation: Herdman KA, Vandermorris S, Davidson S, Au A, Troyer AK. Comparable achievement of client-identified, self-rated goals in intervention and no-intervention groups: reevaluating the use of Goal Attainment Scaling as an outcome measure. Neuropsychol Rehabil. 2019 Dec;29(10):1600-1610. doi: 10.1080/09602011.2018.1432490. Epub 2018 Feb 12.