louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT05269238: Improvement of the Performance of Lumbar Punctures After Training Students With an Augmented Reality SIMulator
Official title: Improvement of the Performance of Lumbar Punctures After Training Students With an Augmented Reality SIMulator
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Lumbar Puncture
Keywords: lumbar puncture
simulator
Lead sponsor: University Hospital, Strasbourg, France
Sponsor class: OTHER
First posted: 2022-03-07
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Lumbar punctures (LP) are frequent invasive procedures that are anxiety-provoking for both the patient and the clinicans performing the procedure. LP is performed by many practitioners, whether they are emergency physicians, neurologists, neurosurgeons, internists or rheumatologists. Learning how to perform LP is essentially done at the patient's bed by showing the students how a procedure is performed and then having them perform it directly on a patient afterwards. The recent development of simulation in health care with the credo "never the first time on the patient" requires the development of training devices faithful to reality.

The rheumatology department of the Strasbourg University Hospital has been working for 3 years, in collaboration with the Strasbourg start-up InSimo, on the development of an LP simulator. This simulator is original because it allows the feeling by pressure of the passage of the various structures, and in particular the yellow ligament. This sensation is made possible by a haptic force feedback device.


Eligibility criteria: Inclusion criteria:

* Requiring a lumbar puncture as part of their routine care
* Male or female of legal age with no upper age limit
* French speaking
* Subject affiliated to a social health insurance scheme
* Not having expressed his or her opposition to the re-use of his or her data in the context of this research

Exclusion criteria:

* Previously undergone a lumbar puncture
* BMI \> 35 kg/m².
* Spinal ankylosis: history of ankylosing spondylitis or Forestier's disease
* Impossible to give the subject informed information (subject in an emergency situation, difficulties in understanding the subject, etc.)
* Subject under court protection
* Subject under guardianship or curatorship
* Contraindication to the use of Emlapatch

Primary outcomes:
measure: Success rate of lumbar punctures in patients according to whether the students performing their first lumbar puncture were previously trained to perform this invasive procedure using the augmented reality simulator versus standard teaching.
timeFrame: 3 days
Secondary outcomes:
Other outcomes:
Locations:
city: Strasbourg
country: France
facility: Hôpitaux Universitaires de Strasbourg
Study officials:
References:
Clinical trial NCT02173938: Novel Psychosocial Influences on Smoking Cessation
Official title: Novel Psychosocial Influences on Successful Tobacco Cessation Among Treatment Seekers
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Smoking
Keywords: Smokers
outpatient
Tobacco Dependence Treatment Program
Lead sponsor: Rutgers, The State University of New Jersey
Sponsor class: OTHER
First posted: 2014-06-25
Enrollment: 61
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult smokers 18 years and older seeking treatment for quitting smoking

Brief summary: Our overall research goal is to determine how these novel psychosocial factors impact cessation. This pilot study will answer how dual use of other tobacco products, direct to consumer marketing, and the new phenomenon of butting-out and relighting influences cessation, and how understanding impulsivity and task persistence could lead to new and improved behavioral interventions for tobacco dependence. Answers to these pilot questions will lead to the publication of several manuscripts and provide important feasibility data to design large, well-powered clinical trials, population-level epidemiological studies, and contribute to furthering the field of tobacco treatment.


Eligibility criteria: Inclusion Criteria:

* smokers 18 years of age or older

Exclusion Criteria:

* non-English speaking participants

Primary outcomes:
measure: Number of patients who have quit smoking
timeFrame: 6 months post quit date
Secondary outcomes:
Other outcomes:
Locations:
city: New Brunswick
country: United States
facility: Tobacco Dependence Program, Rutgers University
state: New Jersey
Study officials:
References:
Clinical trial NCT05373238: Same Day Discharge After Laparoscopic Hysterectomy
Official title: Same Day Discharge After Laparoscopic Hysterectomy vs Late Discharge
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Surgery--Complications
Lead sponsor: Bezmialem Vakif University
Sponsor class: OTHER
First posted: 2022-05-13
Enrollment: 194
Sex: FEMALE
Minimum age (years): 35
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Female patients aged 35-80 scheduled for laparoscopic hysterectomy

Brief summary: Patients who are scheduled for laparoscopic hysterectomy will be included in the study.

After the operation, those who are well and without major distress will be discharged from the hospital before 24 hours. Those who have pain or have additional health problems will be observed further.

Our aim is to compare these two groups in terms of early complications and operation characteristics.


Eligibility criteria: Inclusion Criteria:

* Patients Scheduled For Hysterectomy

Exclusion Criteria:

* Diagnosis of Malignancy
* Those with intraoperative complication

Primary outcomes:
measure: Complication in 30 days
timeFrame: 30 days
Secondary outcomes:
measure: Postop hb
timeFrame: 30 day
measure: Postop htc
timeFrame: 30 day
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakif University
Study officials:
affiliation: Bezmialem Vakif University
name: Gurkan Kiran
role: STUDY_CHAIR
References:
Clinical trial NCT02504138: A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Hepatic Protection During Living-donor Liver Transplantation
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: End Stage Liver Disease
Lead sponsor: Yonsei University
Sponsor class: OTHER
First posted: 2015-07-21
Enrollment: 136
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Renal ischemia/reperfusion (I/R)-induced injury is known to be associated with immediate and long-term hepatic dysfunction after liver transplantation. Protecting the liver against I/R injury and maintaining hepatic function during transplant surgery is therefore very important in order to improve post-operative outcome. This purpose of this study is to investigate whether propofol anesthesia done in both liver donors and recipients during living-donor liver transplantation is effective in reducing liver I/R injury via its antioxidant and antiinflammatory properties and improve post-transplant outcome compared to desflurane anesthesia.


Eligibility criteria: Inclusion Criteria:

(1) Adult liver donors and recipients scheduled for liver transplantation

Exclusion Criteria:

1. Patient refusal
2. Hypersensitivity to propofol, soybeans or peanuts
3. History of vitamin C or E intake within 5 days before surgery
4. History of acute myocardial infarct within 6 months before surgery
5. Congestive heart failure (NYHA III-IV)
6. Autoimmune disease patients
7. BMI over 30 kg/m2
8. Left ventricular ejection fraction less than 35% upon preoperative echocardiography

Primary outcomes:
measure: hepatic function
timeFrame: from 48hr before anesthesia, 1 hour after reperfusion, 1 hour after end of operation, every 24 hours daily up to 7 days postoperatively
Secondary outcomes:
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Study officials:
References:
citation: Shin S, Joo DJ, Kim MS, Bae MI, Heo E, Lee JS, Kim DW, Yoo YC. Propofol intravenous anaesthesia with desflurane compared with desflurane alone on postoperative liver function after living-donor liver transplantation: A randomised controlled trial. Eur J Anaesthesiol. 2019 Sep;36(9):656-666. doi: 10.1097/EJA.0000000000001018.
Clinical trial NCT06552338: Wellness of Osteopathic Medical Students Throughout Their Training (Well-COM)
Official title: The Wellness of Students Enrolled in Osteopathic Medical Schools Through Medical School and Residency Training
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Students, Medical
Lead sponsor: Sam Houston State University
Sponsor class: OTHER
First posted: 2024-08-14
Enrollment: 650
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Target population is students enrolled in osteopathic medical school

Brief summary: The Well-COM Research Project addresses a critical gap in our understanding of the holistic health of medical students, over the entirety of the medical school experience. While the rigorous demands of medical education and its effects on the well-being of medical students are well-documented, there is a lack of long-term study assessing the mental, physical, and metabolic health of medical students from entry into medical school through their training and into residency. By collecting holistic health data from new first-year medical students, and over a minimum period of 10 years, the Well-COM project aims to provide invaluable insights into the changes in health and wellness experienced by medical students, thereby informing future interventions and support systems to promote overall health and resilience in medical school students.


Eligibility criteria: Inclusion Criteria:

* Medical student enrolled in SHSU college of osteopathic medicine.

Exclusion Criteria:

-

Primary outcomes:
measure: Burnout Index
timeFrame: Change over 10 years
measure: Quality of Life Survey
timeFrame: Change over 10 years
measure: Physical Fitness VO2 max
timeFrame: Change over 10 years
measure: Body Fat Percentage
timeFrame: Change over 10 years
measure: Handgrip strength
timeFrame: Change over 10 years
measure: Total cholesterol
timeFrame: Change over 10 years
measure: Blood pressure
timeFrame: Change over 10 years
measure: Perceived Stress
timeFrame: Change over 10 years
measure: Physical Activity
timeFrame: Change over 10 years
Secondary outcomes:
Other outcomes:
Locations:
city: Conroe
country: United States
facility: Sam Houston State University College of Osteopathic Medicine
state: Texas
Study officials:
affiliation: Sam Houston State University
name: Patrick Davis
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03878238: A Pilot Study to Evaluate the Effect of a Probiotic Mixture in Acne
Official title: Randomized, Double Blind and Placebo-controlled Pilot Study to Evaluate the Effect of a Probiotic Mixture in Acne Vulgaris
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Acne
Acne Vulgaris
Keywords: Probiotic
Lead sponsor: Bionou Research, S.L.
Sponsor class: NETWORK
First posted: 2019-03-18
Enrollment: 25
Sex: ALL
Minimum age (years): 12
Maximum age (years): 30
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A 12-week randomized, double-blind, placebo-controlled pilot study to evaluate the effect of a probiotic blend in the treatment and clinical and subjective evolution of acne vulgaris in adolescent and adult patients between 12 and 30 years.


Eligibility criteria: Inclusion Criteria:

* Signature of informed consent by the patient (and their legal guardian in case of being under age).
* Age between 12 and 30 years-old.
* Moderate acne according to the AGSS (Acne Global Severity Scale) and / or GAGS (Global Acne Grading System) scales.

Exclusion Criteria:

* Contraindication of any of the components of the product under study.
* Topical or systemic use of antifungals and antibiotics in the previous 2 weeks.
* Consumption of probiotics in the previous 2 months.
* Use of systemic retinoids in the previous 6 months.

Primary outcomes:
measure: Change from baseline in GAGS (Global Acne Grading System) index score at 12 weeks
timeFrame: 12-week
Secondary outcomes:
measure: AGSS (Acne Global Severity Scale) index score
timeFrame: 0, 6 and 12-week
measure: Number of acne lesions
timeFrame: 0, 6 and 12-week
measure: Patient subjective evaluation
timeFrame: 0, 6 and 12-week
measure: Adherence to treatment
timeFrame: 12-week
measure: Treatment safety assessed by number of adverse events
timeFrame: 12-week
Other outcomes:
Locations:
city: Valencia
country: Spain
facility: Hospital Vithas Nisa 9 de Octubre
Study officials:
References:
Clinical trial NCT05972538: Clinical Performance and Stability of Different Types of Implant Supported Overdenture
Official title: Clinical Performance and Stability of Different Types of Implant Supported Overdenture
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Complete Edentulism
Keywords: Implant stability
Pocket depth
Patient Satisfaction
Overdentures
Lead sponsor: National Research Centre, Egypt
Sponsor class: OTHER
First posted: 2023-08-02
Enrollment: 6
Sex: MALE
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: two groups.Group I received ball and socket retained mandibular implant overdenture while Group II received cement retained implant supported fixed bridges
Primary purpose: TREATMENT

Brief summary: A Total number of 36 implants were installed in 6 patients having mandibular single denture.

The patients were divided into two groups according to the definitive prosthesis.

Group I received ball and socket retained mandibular implant overdenture while Group II received cement retained implant supported fixed bridges.

Detailed description: Implant's stability, clinical performance (gingival index, pocket depth, plaque index and bleeding on probing) and patient's satisfaction were performed after 15, 30,60 and 90 days after prosthesis delivery

Eligibility criteria: Inclusion Criteria:

* highly co-operative
* non-smoker
* systemically free from any chronic diseases

Exclusion Criteria:

* immunocompromised patients
* patients having knife edge, flat or flabby ridge,
* patients having T. M. J disorders

Primary outcomes:
measure: Assessment of change in implant stability
timeFrame: on the 15th, 30th, 60th and 90th days of overdenture insertion
measure: Assessment of change in implants clinical performance throughout the follow-up period.
timeFrame: on the 15th, 30th, 60th and 90th days of over denture insertion.
Secondary outcomes:
measure: Assessment of patient satisfaction
timeFrame: on the 90th day of prosthesis delivery
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: National Research Centre
state: Dokki
Study officials:
affiliation: National Research Centre, Egypt
name: Asmaa N. Elboraey, Asso, Prof
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02483338: FASS (Facial Action Summary Score) Scale to Differentiate the Pain of Postoperative Anxiety in Children Under 7 Years
Official title: Does the FASS (Facial Action Summary Score) Scale Allow to Differentiate the Pain of Postoperative Anxiety in Children Under 7 Years?
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Postoperative Pain
Keywords: Psychometric validity
Pain scale
Postoperative
Children
Lead sponsor: University Hospital, Montpellier
Sponsor class: OTHER
First posted: 2015-06-26
Enrollment: 150
Sex: ALL
Maximum age (years): 7
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: This study aims to evaluate the psychometric validity of FASS (Facial Summary Score Scale) to assess postoperative children pain.


Eligibility criteria: Inclusion Criteria:

* Children surgery
* Younger than 7 years old
* Elective surgery
* Patient whose parents will have given their non-opposition

Exclusion Criteria:

* Psychological retardation
* Chronic pain

Primary outcomes:
measure: FASS (Facial Action Summary Score)
timeFrame: As soon as the child arrive in recovery room or / and the extubation, before and after the administration of analgesics
Secondary outcomes:
Other outcomes:
Locations:
city: Montpellier
country: France
facility: University hospital Lapeyronie
Study officials:
affiliation: Department of Anesthesia Resuscitation at the Hospital Lapeyronie in Montpellier
name: Sophie SB BRINGUIER, HP
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01882738: Effect of Maternal BMI on Measurement of Cervical Length
Official title: Effect of Maternal BMI on Accuracy of Measurement of Cervical Length During the 3rd Trimester of Pregnancy
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: PREGNANCY
Keywords: Cervical length
BMI
Lead sponsor: Hillel Yaffe Medical Center
Sponsor class: OTHER_GOV
First posted: 2013-06-20
Enrollment: 300
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All pregnant women in 2nd or 3rd trimester who attend routine ultrasound exam

Brief summary: All consecutive pregnant patients in 2nd or 3rd trimester will be asked to participate. Cervical length will be assessed in all patients, once abdominally and then vaginally (that would serve as golden standard). Correlation would be assessed between accuracy of measurement to BMI

Detailed description: This study will include pregnant women in either 2nd or 3rd trimester of pregnancy. All consecutive pregnant patients in 2nd or 3rd trimester who will attend our unit for routine ultrasound exam will be asked to participate. Cervical length will be assessed in all patients, once abdominally and then vaginally (that would serve as golden standard). Correlation would be assessed between accuracy of measurement to BMI. Accuracy would be defind as the delta of cervical length between abdominal and vaginal routs.

BMI would be calculated prior to the ultrasound exam (by weighing and measuring all patients).

Eligibility criteria: Inclusion Criteria:

* All pregnant women in 2nd or 3rd trimester who attend routine ultrasound exam

Exclusion Criteria:

* Known shore cervix
* PPROM

Primary outcomes:
measure: Accuracy of cervical length according to BMI
timeFrame: 1 year
Secondary outcomes:
measure: Gestational age at delivery according to cervical length
timeFrame: 1 year
Other outcomes:
Locations:
city: Hadera
country: Israel
facility: Hillel Yaffe Medical Center
Study officials:
References:
Clinical trial NCT00234338: Study Evaluating Prevenar in High-Risk Children
Official title: Prospective Post-Marketing Surveillance Study of Prevenar in High-Risk Children Aged 2 to 5 Years
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pneumococcal Disease
Keywords: Children
Vaccine
Prevenar
Lead sponsor: Wyeth is now a wholly owned subsidiary of Pfizer
Sponsor class: INDUSTRY
First posted: 2005-10-06
Enrollment: 5000
Sex: ALL
Minimum age (years): 2
Maximum age (years): 5
Standard ages: CHILD
Accepts healthy volunteers: yes
Time perspective: PROSPECTIVE

Brief summary: The purpose of this study is to estimate the local and systemic tolerability of Prevenar in children ages 2 to 5 years old in usual care settings.


Eligibility criteria: Inclusion Criteria:

* High-risk children ages 2 to 5 years old

Exclusion criteria:

* Prior administration of Prevenar
* Prior and/or concurrent administration of 23 vPs vaccine

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Frankfurt
country: Germany
Study officials:
affiliation: Wyeth is now a wholly owned subsidiary of Pfizer
name: Medical Monitor
role: STUDY_DIRECTOR
affiliation: For Germany, MedInfoDEU@wyeth.com
name: Trial Manager
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05543538: Influence of Different Teaching Strategies on the Academic Performance and Caring of Nursing Students
Official title: Influence of Different Teaching Strategies on the Academic Performance and Caring of Nursing Students
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Nursing Students
Older People
Lead sponsor: Central Taiwan University of Science and Technology
Sponsor class: OTHER
First posted: 2022-09-16
Enrollment: 222
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: OTHER

Brief summary: The participants in this study are college students with studying long-term care. After different teaching strategies, the students are hypothesised to improve their caring ability in the future and apply rhythmic muscle training programmes.

Therefore, this study will explore the relationship amongst three different teaching strategies of nursing students through multimedia audio-visual, multimedia audio-visual and experiential learning programmes and teachers' personal demonstration and experiential learning, as well as identify their relationship with caring ability.


Eligibility criteria: Inclusion Criteria:

1. Students aged 20 or above who have taken long-term care/long-term care-related courses.
2. Participate in this Community elders of the research project, aged 50 or above.

Exclusion Criteria:

1. No willingness to participate in the research.
2. Exercise taboos or physical health factors, such as severe frailty cases, severe illnesses Emotional instability, injury and inability to walk, pregnancy, etc.
3. Elders or students who cannot communicate in Chinese/Taiwanese.

Primary outcomes:
measure: Caring Assessment
timeFrame: 12 weeks
measure: Caring attitude
timeFrame: 12 weeks
measure: Caring Perception Behavior
timeFrame: 12 weeks
measure: Selfishness
timeFrame: 12 weeks
measure: behavioral intention of caring
timeFrame: 12 weeks
measure: The caring ability inventory
timeFrame: 12 weeks
measure: test for muscle strength training program
timeFrame: 12 weeks
measure: idea transformation questionnaire
timeFrame: 12 weeks
measure: service-learning experience of scale for caring
timeFrame: 12 weeks
Secondary outcomes:
measure: a caring scale for older adults
timeFrame: 12 week
Other outcomes:
measure: Demographics
timeFrame: 12 weeks
Locations:
city: Taichung
country: Taiwan
facility: Central Taiwan University of Science and Technology
Study officials:
affiliation: Central Taiwan University of Science and Technology
name: Chiu
role: PRINCIPAL_INVESTIGATOR
References: