Clinical trial NCT06456788: Barriers and Facilitators to MMR Vaccination Among Healthcare Workers
Official title: Exploring Barriers and Facilitators to Uptake of the MMR Vaccine Among Healthcare Workers at King's College Hospital NHS Foundation Trust
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Measles
Lead sponsor: King's College London
Sponsor class: OTHER
Collaborators: name: King's College Hospital NHS Trust
name: UK Health Security Agency
First posted: 2024-06-13
Enrollment: 23
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Participants will be recruited from a population of hospital-based healthcare workers, including doctors, nurses, health assistants, etc. Healthcare workers will be recruited from one site only (KCH).

Brief summary: Measles is a highly contagious disease which can result in severe complications in some patients. Healthcare workers have a higher risk of getting measles than the general population because of their increased risk of exposure from patients with measles attending hospitals. Having had measles in the past or at least one dose of the measles, mumps and rubella (MMR) vaccine provides protection (immunity) against measles. UK government guidelines therefore recommend that healthcare workers and non-clinical staff with direct patient contact are fully vaccinated or have other evidence of immunity. Yet, evidence from recent measles outbreaks suggests that some healthcare workers are not immune or do not know if they are immune, with implications for containment efforts, cost and transmission. The purpose of this study is to identify barriers and facilitators to uptake of the MMR vaccine among healthcare workers at King's College Hospital NHS Foundation Trust (KCH). KCH healthcare workers will be eligible to take part in the study if they are aged 18 and over and have direct contact with patients. In addition, the research will focus on four subgroups of healthcare workers at KCH: those who are not immune, those who have not completed the full vaccination schedule, those who don't know their immunity status, those received the vaccine only after joining KCH. The latter may provide insights into facilitators to vaccine uptake. Measles immunity forms part of the occupational health screening at KCH. A series of semi structured interviews lasting approximately 1 hour will explore participants' experiences of the occupational health vaccine screening process and measles vaccine campaigns at KCH; why they are unvaccinated/not fully vaccinated/do not know if they are immune/decided to be vaccinated after joining KCH; and what measures or interventions may help healthcare workers when deciding whether to get the MMR vaccine.


Eligibility criteria: Inclusion Criteria:

* Are aged 18 and over
* Currently work as a healthcare worker at the Trust
* Have direct contact with patients
* Don't know if they have had measles and don't know if they have been vaccinated
* Or: Have not had measles and have not received the MMR vaccine
* Or: Have only received 1 dose of the MMR vaccine
* Or: Received the MMR vaccine after joining the Trust

Exclusion Criteria:

* Are aged \<18 years old
* Work in a role at the Trust that does not involve direct contact with patients (e.g., administrative or business staff)
* Are sure and/or have evidence that they have had measles in the past or both doses of the MMR vaccine before joining the Trust
* Are not able to give informed consent

Primary outcomes:
measure: Barriers to MMR vaccination
timeFrame: Collected at one timepoint 1 day during qualitative interview
measure: Facilitators to MMR vaccination
timeFrame: Collected at one timepoint 1 day during qualitative interview
measure: Reasons for not knowing immunity status
timeFrame: Collected at one timepoint 1 day during qualitative interview
Secondary outcomes:
measure: Experiences of the occupational health vaccine screening process at KCH
timeFrame: Collected at one timepoint 1 day during qualitative interview
Other outcomes:
Locations:
city: London
country: United Kingdom
facility: King's College London
Study officials:
References: