Clinical trial NCT04343781: National Survey of Symptoms of People Aged 70 and Overs Diagnosed With COVID-19
Official title: National Survey of Symptoms of People Aged 70 and Overs Diagnosed With COVID-19
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: SARS-CoV-2
COVID-19
Lead sponsor: University Hospital, Angers
Sponsor class: OTHER_GOV
First posted: 2020-04-13
Enrollment: 353
Sex: ALL
Minimum age (years): 70
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: all older French patients infected by SARS-CoV-2

Brief summary: Cross-sectional study based on a French national survey aimed to described and identify the most frequent symptoms of COVID-19 older patients.

Detailed description: This cross-sectional survey was initiated and conducted by the French Society of Geriatrics and Gerontology. A standardized questionnaire was emailed to 1600 geriatrician members of the French Society of Geriatrics and Gerontology throughout France between March 22, 2020 and April 5, 2020. Geriatricians were asked to complete the survey for their last 10 patients infected by the SARS-CoV-2. The study was declared to the Commission Nationale de l'Informatique et des Libertés (CNIL) under the number ar20-0031v1.

For each patient, demographic characteristics (age, gender, residence place, care place, autonomy according to the Groupe Iso Ressource (GIR)), medical history (presence of major neurocognitive disorder, hypertension, diabetes, asthma or chronic obstructive pulmonary disease (COPD), heart pathology, severe renal failure with a clearance of creatinine under 30ml/min, solid or liquid cancer) were collected. The symptoms within de 72 hours of the actual disease were also collected for each patient including geriatric syndromes (fall, hypoactive or hyperactive delirium, altered general status, altered conscience), general symptoms (temperature, blood pressure), respiratory symptoms (cough, polypnea), ear nose and throat (ENT) symptoms (rhinorrhea, odynophagia, otalgia, conjunctivitis, ageusia or dysgeusia, anosmia), digestive symptoms (diarrhea, nausea or vomiting), and blood formula modification (leucopenia (with count if available), lymphopenia (with count if available), thrombopenia (with count if available).

Procedure Data were collected by the physician who was in charge of the patient between March 22, 2020 and April 5, 2020.

Given the main objective of the study was only descriptive, no calculation was required concerning the number of subjects to include in the study.

Eligibility criteria: Inclusion Criteria:

* confirmed COVID-19 defined by a positive RT-PCR to SARS-CoV-2

Exclusion Criteria:

* none

Primary outcomes:
measure: symptoms of COVID-19 in older patients
timeFrame: at baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Angers
country: France
facility: Angers University Hospital
Study officials:
affiliation: University Hospital, Angers
name: Cédric Annweiler, M.D., Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Annweiler C, Sacco G, Salles N, Aquino JP, Gautier J, Berrut G, Guerin O, Gavazzi G. National French Survey of Coronavirus Disease (COVID-19) Symptoms in People Aged 70 and Over. Clin Infect Dis. 2021 Feb 1;72(3):490-494. doi: 10.1093/cid/ciaa792.