Clinical trial NCT04890990: Reducing Depression-related Stigma and Increasing-treatment Seeking Among Black Adolescents
Official title: Reducing Depression-related Stigma and Increasing-treatment Seeking Among Black Adolescents
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Depression
Racism
Lead sponsor: Yale University
Sponsor class: OTHER
First posted: 2021-05-18
Enrollment: 1291
Sex: ALL
Minimum age (years): 14
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purposes of this study are to:

1. test among adolescent the utility of brief video-based interventions to reduce stigma-related attitudes and increase help-seeking intentions toward depression;
2. examine the role of race (Black vs other) as an independent factor in the primary outcome.

Detailed description: Intervention videos will each be of \~120-second duration and feature an underage female professional (age 16) acting as a simulated patient. All three videos will focus on her as an empowered presenter with depression sharing her personal story regarding depression and describe how social supports from family, friends, and community, as well as professional help assisted her in overcoming symptoms of the illness.

Assessments will occur at baseline and post-intervention, and will include:

1. Demographics (baseline only);
2. Primary outcome: Depression-related stigma(Depression Stigma Scale \[DSS\]) summary score.
3. Secondary outcomes: a. DSS individual items; b. Help-seeking (General Help-Seeking Questionnaire \[GHSQ\]) summary score and individual items; and bc Racial attitudes: feelings thermometers.

The investigators intend to randomly assign \~1,000 individuals aged 14-18 as follows:

Subjects oversampled for Black participants (50% Black; 50% other);

Randomized, in equal proportions, and stratified by race, to view one of three \~120-second videos of a girl with:

1. No depression control (Black; BC);
2. Depression (Black, following same script as in our earlier study (Amsalem and Martin, 2021), DB); and
3. Depression adjusted (Black, with script adjusted based on input from focus group of Black girls and women; DBa).

Eligibility criteria: Inclusion Criteria:

* English-speaking
* Living in the US
* Ages 14 - 18

Exclusion Criteria:

* None

Primary outcomes:
measure: Change in Depression-related stigma (Depression Stigma Scale [DSS]; Personal component only): TOTAL SCORE
timeFrame: Before / after viewing videos (within 10 minutes)
Secondary outcomes:
measure: Change in Help-seeking (General Help-Seeking Questionnaire [GHSQ]; Emotional and Suicide components): MEAN SCORE
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in Racial attitudes: feelings thermometer
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 10
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 10
timeFrame: Before / after viewing videos (within 10 minutes)
Other outcomes:
Locations:
city: New Haven
country: United States
facility: Yale Child Study Center
state: Connecticut
Study officials:
References:
citation: Griffiths KM, Christensen H, Jorm AF, Evans K, Groves C. Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomised controlled trial. Br J Psychiatry. 2004 Oct;185:342-9. doi: 10.1192/bjp.185.4.342.
citation: Wilson CJ, Deane FP, Marshall KL, Dalley A. Adolescents' suicidal thinking and reluctance to consult general medical practitioners. J Youth Adolesc. 2010 Apr;39(4):343-56. doi: 10.1007/s10964-009-9436-6. Epub 2009 Jul 15.
citation: Norton AT, Herek GM. Heterosexuals' attitudes toward transgender people: findings from a national probability sample of US Adults. Sex Roles. 2013;68(11-12):738-753. doi:10.1007/s11199-011-0110-6
citation: Martin A, Calhoun A, Paez J, Amsalem D. Destigmatizing perceptions about Black adolescent depression: randomized controlled trial of brief social contact-based video interventions. J Child Psychol Psychiatry. 2022 Nov;63(11):1270-1278. doi: 10.1111/jcpp.13570. Epub 2022 Jan 23.