Clinical trial NCT06969911: Clinical Evaluation of CAD/CAM vs. Conventional Veneer Restorations
Official title: Long-term Performance and Longevity of Minimally Invasive CAD/CAM Versus Conventional Anterior Veneer Restorations: a Randomized Controlled Trial Over 5 Years.
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Malformed Tooth
Lead sponsor: Heinrich-Heine University, Duesseldorf
Sponsor class: OTHER
First posted: 2025-05-14
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study is to clinically evaluate tooth-supported veneer restorations fabricated using the CAD/CAM process in comparison to conventionally manufactured pressed veneers on anterior teeth and to assess their long-term performance. Survival and success rates of anterior veneer restorations, as well as patient satisfaction, will be evaluated.

Detailed description: Functional and aesthetic complaints caused by congenital malformations and acquired tooth damage are widely spread. Discomfort involves reduced chewing ability, phonetic problems, hypersensitivity and aesthetic impairments.

Conventionally fabricated all-ceramic veneer restorations reveal a long history of clinical success in minimally invasive rehabilitation of the anterior dentition. Nevertheless, conventional manufacturing techniques are prone to fabrication mistakes and must be handled by experienced dental technicians and dentists which results in very high fabrication costs. Therefore, access to minimally invasive restorations is currently restricted for most of the patients. Innovative CAD/CAM techniques have revolutionised restorative treatment options over the last decades and have made all-ceramic restorations more affordable for patients. With further improvements of the CAD/CAM milling devices the machinability of high-strength glass ceramic is now possible.

The aim of both treatment procedures will be to avoid any extensive additional tooth structure removal, to provide long-term survival and success of the integrated restorations and to improve patient´s satisfaction. Up to now scientific evidence on the clinical performance of CAD/CAM fabricated veneers is very limited. Aim of this trial is to evaluate if the clinical performance of anterior restorations after minimally invasive therapeutic intervention with CAD/CAM veneers compared to conventionally fabricated veneers. Functional and aesthetic treatment results will be assessed for five years and evaluated with regard to failure and succes veneer restorations as well as patient satisfaction.

Eligibility criteria: Inclusion Criteria:

* Patients ≥ 18 years of age
* Patients that reveal indication for a minimum of 2 and a maximum of 6 anterior veneer restorations

Exclusion Criteria:

- Patients that reveal multiple missing teeth, poor oral hygiene, pronounced parafunctions or with allergies to any of the applied materials

Primary outcomes:
measure: Prosthetic survival time
timeFrame: 5 Years
Secondary outcomes:
measure: Prosthetic success
timeFrame: 5 Years
Other outcomes:
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