Clinical trial NCT01081028: Connect® MM- The Multiple Myeloma Disease Registry
Official title: Connect® MM- The Multiple Myeloma Disease Registry
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Multiple Myeloma
Keywords: Multiple Myeloma
MM
disease registry
Connect®
Lead sponsor: Celgene
Sponsor class: INDUSTRY
First posted: 2010-03-05
Enrollment: 3033
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with newly diagnosed multiple myeloma and being treated in community or academic settings in the United States

Brief summary: The purpose of the Connect® MM Registry is to explore the natural history and real world management of patients with newly diagnosed symptomatic multiple myeloma (MM) and provide unique insights into the management of MM and the impact of this hematologic disorder on patients.


Eligibility criteria: Inclusion Criteria:

Cohort 1 and 2

* Newly diagnosed with symptomatic MM within 2 months of enrollment in Connect® MM registry
* Age ≥18 years
* Willing and able to provide signed informed consent
* Agrees to complete patient assessment questionnaires either alone or with minimal assistance from caregivers and/or trained site personnel

Cohort 3

* Received 1L therapy for symptomatic active MM and subsequently has evidence of disease progression. Prior 1L MM treatment received, including anti-myeloma therapy, transplant, chemotherapy, radiation, and surgery, must be known.
* Initiated or intends to initiate 2L systemic therapy for MM after the first documented relapsed/refractory date (i.e. 1L PD).
* Enrollment date must be within 90 days of start date (or intended start date) of 2L systemic therapy.

Exclusion Criteria:

Cohort 1 and 2

- None

Cohort 3

* Patient's 1L MM treatment was for smoldering MM or MGUS, and not for symptomatic MM
* Currently active in any MM Registry, including but not limited to, the Connect® MM registry or another Celgene/BMS-Sponsored registry.
* Patients who have discontinued from Connect® MM or another Celgene/BMS-Sponsored registry could be considered for enrollment in Cohort 3, if inclusion and exclusion criteria are met.
* Currently enrolled or intending to enroll within 90 days in any interventional clinical trial in which any treatment is an investigational product that cannot be identified

Primary outcomes:
measure: Participant baseline demographics
timeFrame: Baseline
measure: Participant medical history
timeFrame: Baseline
measure: Participant Multiple Myeloma diagnosis information
timeFrame: Baseline
measure: Participant Multiple Myeloma treatment history
timeFrame: Baseline
measure: Multiple Myeloma-related supportive concomitant medications and procedures
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3), or up to 16 years (Cohort 1 & 2), or date of early discontinuation
measure: Occurance of second primary malignancy
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3), or up to 16 years (Cohort 1 & 2), or date of early discontinuation
measure: Number of participants enrolled in a clinical trial
timeFrame: Baseline, every 3-months up to 16 years or date of early discontinuation
measure: Lines of therapy prescribed
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3), or up to 16 years (Cohort 1 & 2), or date of early discontinuation
measure: Participant disease response assessment results
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3), or up to 16 years (Cohort 1 & 2), or date of early discontinuation
Secondary outcomes:
measure: Participant socioeconomic status
timeFrame: Baseline
measure: Participant EuroQol-5 Dimensions (EQ-5D) questionnaire results
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2), or date of early discontinuation
measure: Participant Functional Assessment of Cancer Therapy - Multiple Myeloma (FACT-MM) questionnaire results
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2), or date of early discontinuation
measure: Participant Visual Analogue Score (VAS) questionnaire results
timeFrame: Baseline, every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2), or date of early discontinuation
measure: Participant participant survival status
timeFrame: Every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2), or date of early discontinuation
measure: Participant participant Adverse Events (AEs)
timeFrame: Every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2) or date of early discontinuation
measure: Reason for registry discontinuation
timeFrame: Date of early discontinuation assessed up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2)
measure: Reason for treatment initiation or discontinuation
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Participant COVID-19 infection and vaccination status
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Treating clinician response to frailty questionnaire
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Participant Brief Pain Inventory (BPI) questionnaire results
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Participant response to social support questionnaire
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Treating clinician response to social support questionnaire
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Number of participants that have received stem cell transplant
timeFrame: Baseline, and every 3-months up to 5 years or date of early discontinuation
measure: Number of hospitalization or emergency room visits
timeFrame: Every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2) or date of early discontinuation
measure: Cause of death
timeFrame: Every 3-months up to 5 years (Cohort 3) or up to 16 years (Cohort 1 and 2) or date of early discontinuation
Other outcomes:
Locations:
city: Huntsville
country: United States
facility: The Cancer Center of Huntsville
state: Alabama
city: Tuscaloosa
country: United States
facility: DCH Health System
state: Alabama
city: Tucson
country: United States
facility: US Oncology - Arizona Oncology Associates - Rudasill
state: Arizona
city: Fort Smith
country: United States
facility: St. Edward Mercy Medical Center
state: Arkansas
city: Hot Springs
country: United States
facility: Genesis Cancer Center
state: Arkansas
city: Jonesboro
country: United States
facility: Clopton Clinic Hematology/Oncology
state: Arkansas
city: Little Rock
country: United States
facility: Little Rock Hematology Oncology Associates, PA
state: Arkansas
city: Anaheim
country: United States
facility: Pacific Cancer Medical Center, Inc
state: California
city: Berkeley
country: United States
facility: Alta Bates Summit Comprehensive Cancer Center
state: California
city: Campbell
country: United States
facility: Southbay Oncology Hematology Partners
state: California
city: Corona
country: United States
facility: Compassionate Cancer Care Medical Group (Corona)
state: California
city: Escondido
country: United States
facility: Southwest Cancer Care
state: California
city: Fountain Valley
country: United States
facility: Compassionate Cancer Care Medical Group (Fountain Valley)
state: California
city: Fullerton
country: United States
facility: Virginia K. Crosson Cancer Center
state: California
city: Lancaster
country: United States
facility: TORI - Antelope Valley Cancer Center
state: California
city: Monterey
country: United States
facility: Monterey Bay Oncology
state: California
city: Northridge
country: United States
facility: TORI - North Valley Hematology/Oncology
state: California
city: Oakland
country: United States
facility: Hematology Oncology Associates
state: California
city: Palm Springs
country: United States
facility: Comprehensive Cancer Center
state: California
city: Pleasant Hill
country: United States
facility: Bay Area Cancer Research Group, LLC
state: California
city: Pomona
country: United States
facility: New Hope Cancer & Research Institute
state: California
city: Riverside
country: United States
facility: Campassionate Cancer Care Medical Group (Riverside)
state: California
city: Roseville
country: United States
facility: Capitol Hematology Oncology Medical Group - Sutter Roseville
state: California
city: Santa Maria
country: United States
facility: TORI - Central Coast Medical Oncology
state: California
city: Santa Rosa
country: United States
facility: Redwood Regional Medical Group, Inc.
state: California
city: Stockton
country: United States
facility: Stockton Hematology Oncology Medical Group, Inc.
state: California
city: West Hollywood
country: United States
facility: Institute for Myeloma and Bone Cancer Research
state: California
city: Aurora
country: United States
facility: US Oncology- Rocky Mountain Cancer Center-Aurora
state: Colorado
city: Boulder
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Boulder
state: Colorado
city: Colorado Springs
country: United States
facility: US Oncology- Rocky Mountain Cancer Center at the Pavillion
state: Colorado
city: Colorado Springs
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Colorado Springs
state: Colorado
city: Denver
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Midtown
state: Colorado
city: Denver
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Rose
state: Colorado
city: Grand Junction
country: United States
facility: TORI - St. Mary's Advanced Medical Pavilion
state: Colorado
city: Lakewood
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Lakewood
state: Colorado
city: Littleton
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Littleton
state: Colorado
city: Lone Tree
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Sky Ridge
state: Colorado
city: Longmont
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Longmont
state: Colorado
city: Parker
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Parker
state: Colorado
city: Thornton
country: United States
facility: US Oncology - Rocky Mountain Cancer Center-Thornton
state: Colorado
city: Fairfield
country: United States
facility: Medical Specialists of Fairfield
state: Connecticut
city: Manchester
country: United States
facility: Medical Oncology and Blood Disorders, LLP
state: Connecticut
city: New Britain
country: United States
facility: Hospital of Central Connecticut
state: Connecticut
city: Stamford
country: United States
facility: Hematology Oncology, PC
state: Connecticut
city: Newark
country: United States
facility: Delaware Clinical & Laboratory Physicians, PA
state: Delaware
city: Boynton Beach
country: United States
facility: Hematology Oncology Associates
state: Florida
city: Boynton Beach
country: United States
facility: University Cancer Institute
state: Florida
city: Boynton Beach
country: United States
facility: Collaborative Research Group
state: Florida
city: Coral Springs
country: United States
facility: Flora Research Associates
state: Florida
city: Deerfield Beach
country: United States
facility: Archbold Cancer Center
state: Florida
city: Deerfield Beach
country: United States
facility: Flora Research Associates
state: Florida
city: Fort Lauderdale
country: United States
facility: Broward Oncology Associates, PA
state: Florida
city: Gainesville
country: United States
facility: Florida Cancer Specialists & Research Institute
state: Florida
city: Hollywood
country: United States
facility: Memorial Cancer Institute
state: Florida
city: Hudson
country: United States
facility: US Oncology - Florida Cancer Institute - New Hope-Hudson
state: Florida
city: Jacksonville
country: United States
facility: Integrated Community Oncology Network, LLC
state: Florida
city: Lakeland
country: United States
facility: Watson Clinic
state: Florida
city: Lecanto
country: United States
facility: Cancer & Blood Disease Center
state: Florida
city: New Port Richey
country: United States
facility: Pasco Hernando Oncology Associates (Kumar)
state: Florida
city: New Port Richey
country: United States
facility: US Oncology - Florida Cancer Institute - New Hope-New Port Richey
state: Florida
city: Pensacola
country: United States
facility: Sacred Heart Medical Oncology Group
state: Florida
city: Rockledge
country: United States
facility: Cancer Care Centers of Brevard
state: Florida
city: The Villages
country: United States
facility: Florida Hospital Waterman-Lake County Oncology & Hematology
state: Florida
city: Weston
country: United States
facility: Cleveland Clinic Florida
state: Florida
city: Albany
country: United States
facility: Phoebe Putney Memorial Hospital
state: Georgia
city: Atlanta
country: United States
facility: Peachtree Hematology-Oncology Consultants
state: Georgia
city: Atlanta
country: United States
facility: Georgia Cancer Specialists
state: Georgia
city: Savannah
country: United States
facility: Summit Cancer Care
state: Georgia
city: Honolulu
country: United States
facility: Straub Clinic and Hospital
state: Hawaii
city: Arlington Heights
country: United States
facility: Cancer Care & Hematology Specialists of Chicagoland, PC
state: Illinois
city: Chicago
country: United States
facility: John H. Stroger, Jr. Hospital of Cook County
state: Illinois
city: Chicago
country: United States
facility: Rush University Medical Center
state: Illinois
city: Chicago
country: United States
facility: Univeristy of Chicago Medical Center, Section of Hematology/Oncology
state: Illinois
city: Elmhurst
country: United States
facility: Elmhurst Memorial Hospital
state: Illinois
city: Evanston
country: United States
facility: Northshore University Health System
state: Illinois
city: Harvey
country: United States
facility: Ingalls Cancer Research Center
state: Illinois
city: Joliet
country: United States
facility: Joliet Oncology
state: Illinois
city: Moline
country: United States
facility: Medical Arts Associates, Ltd
state: Illinois
city: Niles
country: United States
facility: Oncology Specialists, S.C.
state: Illinois
city: Peoria
country: United States
facility: Illinois Cancer Care
state: Illinois
city: Skokie
country: United States
facility: Orchard Research
state: Illinois
city: Urbana
country: United States
facility: Carle Cancer Center
state: Illinois
city: Beech Grove
country: United States
facility: Indiana Blood and Marrow Transplant, LLC
state: Indiana
city: Beech Grove
country: United States
facility: St. Francis Cancer Research
state: Indiana
city: Goshen
country: United States
facility: Center for Cancer Care @ Goshen Health Systems
state: Indiana
city: Indianapolis
country: United States
facility: Indiana University Cancer Center Clinical Research Office
state: Indiana
city: Munster
country: United States
facility: Cancer Research-Munster
state: Indiana
city: New Albany
country: United States
facility: Cancer Care Center Inc.
state: Indiana
city: Newburgh
country: United States
facility: Oncology Hematology Associates of SW IN
state: Indiana
city: South Bend
country: United States
facility: Northern Indiana Cancer Research Consortium
state: Indiana
city: Ames
country: United States
facility: McFarland Clinic
state: Iowa
city: Bettendorf
country: United States
facility: Hematology Oncology Associates of the Quad Cities
state: Iowa
city: Cedar Rapids
country: United States
facility: Iowa Blood and Cancer Care of PCI
state: Iowa
city: Sioux City
country: United States
facility: Siouxland Hematology-Oncology Associates, LLP
state: Iowa
city: Waterloo
country: United States
facility: Cedar Valley Medical Specialists
state: Iowa
city: Waterloo
country: United States
facility: Covenant Clinic
state: Iowa
city: Wichita
country: United States
facility: Cancer Center of Kansas, PA
state: Kansas
city: Louisville
country: United States
facility: Baptist Hospital East
state: Kentucky
city: Baton Rouge
country: United States
facility: Mary Bird Perkins Cancer Center
state: Louisiana
city: Westminster
country: United States
facility: Alliance Hematology Oncology, PA
state: Maryland
city: Hyannis
country: United States
facility: Capecod Hospital/Davenport Mugar Cancer Center
state: Massachusetts
city: Worcester
country: United States
facility: Fallon Clinic
state: Massachusetts
city: Bay City
country: United States
facility: Michigan State University/Bay Regional Medical Center
state: Michigan
city: Flint
country: United States
facility: Genesys Hurley Cancer Institute
state: Michigan
city: Flint
country: United States
facility: Michigan State University/McLaren Regional Medical Center
state: Michigan
city: Kalamazoo
country: United States
facility: West Michigan Cancer Center
state: Michigan
city: Lansing
country: United States
facility: Michigan State University/Breslin Cancer Center
state: Michigan
city: Lapeer
country: United States
facility: Michigan State University/Lapeer Regional Medical Center
state: Michigan
city: Mount Clemens
country: United States
facility: Michigan State University/Mount Clemens Regional Medical Center
state: Michigan
city: Novi
country: United States
facility: Newland Medical Associates
state: Michigan
city: Owosso
country: United States
facility: Michigan State University/Memorial Cancer Center
state: Michigan
city: Southfield
country: United States
facility: Newland Medical Associates
state: Michigan
city: Duluth
country: United States
facility: Duluth Clinic Cancer Center
state: Minnesota
city: Saint Louis Park
country: United States
facility: Park Nicollet Institute - Louisiana Ave.
state: Minnesota
city: Jackson
country: United States
facility: Jackson Oncology Associates
state: Mississippi
city: Chesterfield
country: United States
facility: St. Louis Cancer Care, LLP
state: Missouri
city: Jefferson City
country: United States
facility: Capitol Comprehensive Cancer Care Clinic
state: Missouri
city: Saint Joseph
country: United States
facility: St. Joseph Oncology
state: Missouri
city: Saint Louis
country: United States
facility: University Hematology Oncology, Inc.
state: Missouri
city: Saint Louis
country: United States
facility: Washington University in St. Louis, Division of Oncology, Section of Bone Marrow Transplantation & Leukemia
state: Missouri
city: Saint Louis
country: United States
facility: Hematology Oncology Consultants, Inc
state: Missouri
city: Saint Louis
country: United States
facility: St. John's Mercy Medical Center
state: Missouri
city: Springfield
country: United States
facility: St. John's Medical Research Institute
state: Missouri
city: Missoula
country: United States
facility: Montana Cancer Institute Foundation
state: Montana
city: Lincoln
country: United States
facility: Nebraska Hematology Oncology, PC
state: Nebraska
city: Lincoln
country: United States
facility: Southeast Nebraska Hematology & Oncology Consultants, PC
state: Nebraska
city: Henderson
country: United States
facility: TORI - Comprehensive Cancer Centers of NV
state: Nevada
city: Las Vegas
country: United States
facility: Southern Nevada Cancer Research Foundation
state: Nevada
city: Reno
country: United States
facility: VA Sierra Nevada Healthcare System
state: Nevada
city: Belleville
country: United States
facility: Essex Oncology of North Jersey, PA
state: New Jersey
city: Cherry Hill
country: United States
facility: The Center for Cancer and Hematologic Disease
state: New Jersey
city: Englewood
country: United States
facility: Drs. Forte, Schleider, Attas & Condemi, PA
state: New Jersey
city: Morristown
country: United States
facility: Hematology-Oncology Associates of Northern NJ dba Carol G. Simon
state: New Jersey
city: Somerville
country: United States
facility: Steeplechase Cancer Center
state: New Jersey
city: Albany
country: United States
facility: US Oncology - New York Oncology Hematology, PC-Albany
state: New York
city: Albany
country: United States
facility: US Oncology - Albany Medical Cancer Center
state: New York
city: Amsterdam
country: United States
facility: US Oncology - Amsterdam Community Cancer Program
state: New York
city: Bronx
country: United States
facility: Bronx River Medical Associates
state: New York
city: Bronx
country: United States
facility: Eastchester Center for Cancer Care
state: New York
city: Buffalo
country: United States
facility: Jonah Cancer Care Center & ECMC
state: New York
city: Hudson
country: United States
facility: US Oncology - Cavell Cancer Treatment Program
state: New York
city: Johnson City
country: United States
facility: Broome Oncology
state: New York
city: Lake Success
country: United States
facility: Arena Oncology Associates, PC
state: New York
city: Latham
country: United States
facility: US Oncology - New York Oncology Hematology, PC-Latham
state: New York
city: Rexford
country: United States
facility: US Oncology - New York Oncology Hematology, PC-Rexford
state: New York
city: Syracuse
country: United States
facility: SUNY Upstate Medical University - Adult Program
state: New York
city: Troy
country: United States
facility: US Oncology - Troy Cancer Treatment Program
state: New York
city: Cary
country: United States
facility: US Oncology - Cancer Centers of North Carolina - Cary
state: North Carolina
city: Durham
country: United States
facility: DUMC Division of Cellular Therapy/ABMT
state: North Carolina
city: Hickory
country: United States
facility: Carolina Oncology Specialists, PA
state: North Carolina
city: High Point
country: United States
facility: Emerywood Hematology/Oncology
state: North Carolina
city: Raleigh
country: United States
facility: US Oncology - Cancer Centers of North Carolina - Falls
state: North Carolina
city: Bismarck
country: United States
facility: Legacy Pharma Research
state: North Dakota
city: Bismarck
country: United States
facility: Med Center One
state: North Dakota
city: Fargo
country: United States
facility: Roger Maris Cancer Center
state: North Dakota
city: Akron
country: United States
facility: Summa Health System - Cancer Research Office
state: Ohio
city: Canton
country: United States
facility: Gabrail Cancer Center Research
state: Ohio
city: Cleveland
country: United States
facility: Cleveland VA Medical Center
state: Ohio
city: Columbus
country: United States
facility: Mid Ohio Oncology/Hematology, Inc
state: Ohio
city: Elyria
country: United States
facility: Hematology Oncology Center, Inc
state: Ohio
city: Wooster
country: United States
facility: Lawrence M. Stallings MD LTD dba Trilogy Cancer Care
state: Ohio
city: Eugene
country: United States
facility: US Oncology - Willamette Valley Cancer Institute - Eugene
state: Oregon
city: Springfield
country: United States
facility: US Oncology - Willamette Valley Cancer Institute - Springfield
state: Oregon
city: Bethlehem
country: United States
facility: Oncology Hematology of Lehigh Valley
state: Pennsylvania
city: Danville
country: United States
facility: Geisinger Medical Center
state: Pennsylvania
city: Drexel Hill
country: United States
facility: Consultants in Medical Oncology and Hematology, PC
state: Pennsylvania
city: Harrisburg
country: United States
facility: Andrews and Patel Associates
state: Pennsylvania
city: Kingston
country: United States
facility: US Oncology - Medical Oncology Associates (Nahar)
state: Pennsylvania
city: Lancaster
country: United States
facility: Lancaster Cancer Center
state: Pennsylvania
city: Pittsburgh
country: United States
facility: The Western Pennsylvania Hospital
state: Pennsylvania
city: Pittsburgh
country: United States
facility: UPCI Hillman Cancer Center
state: Pennsylvania
city: Reading
country: United States
facility: Berks Hematology Oncology Associates
state: Pennsylvania
city: Cranston
country: United States
facility: Hematology & Oncology Associates of Rhode Island
state: Rhode Island
city: Charleston
country: United States
facility: Charleston Hematology Oncology Associates, PA
state: South Carolina
city: Easley
country: United States
facility: US Oncology - Cancer Centers of the Carolinas - Easley
state: South Carolina
city: Greenville
country: United States
facility: US Oncology - Cancer Centers of the Carolinas - Butternut
state: South Carolina
city: Greenville
country: United States
facility: US Oncology - Cancer Centers of the Carolinas - West Faris
state: South Carolina
city: Greenville
country: United States
facility: US Oncology - Cancer Centers of the Carolinas - Eastside
state: South Carolina
city: Hilton Head Island
country: United States
facility: SC Cancer Specialists, PA
state: South Carolina
city: Seneca
country: United States
facility: US Oncology - Cancer Center of the Carolinas - Seneca
state: South Carolina
city: Spartanburg
country: United States
facility: US Oncology - Cancer Centers of the Carolinas - Spartanburg
state: South Carolina
city: Sioux Falls
country: United States
facility: Sanford Clinic
state: South Dakota
city: Sioux Falls
country: United States
facility: Avera Cancer Institute
state: South Dakota
city: Collierville
country: United States
facility: Family Cancer Center, PLLC
state: Tennessee
city: Nashville
country: United States
facility: SCRI
state: Tennessee
city: Abilene
country: United States
facility: US Oncology - Texas Cancer Center - Abilene (South)
state: Texas
city: Amarillo
country: United States
facility: US Oncology - Texas Oncology, PA - Amarillo
state: Texas
city: Arlington
country: United States
facility: US Oncology - Texas Oncology - Arlington South
state: Texas
city: Austin
country: United States
facility: US Oncology - Texas Oncology - Midtown
state: Texas
city: Austin
country: United States
facility: US Oncology - Texas Oncology Cancer Center
state: Texas
city: Austin
country: United States
facility: US Oncology - South Austin Cancer Center
state: Texas
city: Austin
country: United States
facility: US Oncology - Texas Oncology North Austin
state: Texas
city: Austin
country: United States
facility: Austin Cancer Centers
state: Texas
city: Austin
country: United States
facility: US Oncology - Southwest Regional Cancer Center - North
state: Texas
city: Bedford
country: United States
facility: US Oncology - Texas Oncology, PA - Bedford
state: Texas
city: Bryan
country: United States
facility: St. Joseph Regional Cancer Center
state: Texas
city: Cedar Park
country: United States
facility: US Oncology - Texas Oncology Cedar Park
state: Texas
city: College Station
country: United States
facility: Scott & White Clinic
state: Texas
city: Corpus Christi
country: United States
facility: South Texas Institute of Cancer
state: Texas
city: Corpus Christi
country: United States
facility: Coastal Bend Cancer Center
state: Texas
city: Dallas
country: United States
facility: US Oncology - Texas Cancer Center at Medical City
state: Texas
city: Dallas
country: United States
facility: US Oncology -Texas Oncology, PA - Dallas
state: Texas
city: El Paso
country: United States
facility: US Oncology - El Paso Cancer Treatment Ctr
state: Texas
city: Fort Worth
country: United States
facility: US Oncology - Texas Oncology, PA - Forth Worth
state: Texas
city: Fort Worth
country: United States
facility: US Oncology - Southwest Forth Worth Cancer Center
state: Texas
city: Garland
country: United States
facility: US Oncology - Texas Oncology, PA - Garland
state: Texas
city: Grapevine
country: United States
facility: US Oncology - Texas Oncology - Grapevine
state: Texas
city: Houston
country: United States
facility: MD Anderson Cancer Center
state: Texas
city: Houston
country: United States
facility: The Methodist Hospital Research Institute-AOCT
state: Texas
city: Irving
country: United States
facility: Southlake Oncology dba Las Colinas Hematology Oncology
state: Texas
city: Kerrville
country: United States
facility: US Oncology - San Antonio Tumor & Blood Clinic - Kerrville
state: Texas
city: Kyle
country: United States
facility: US Oncology - Texas Oncology - Kyle
state: Texas
city: Longview
country: United States
facility: US Oncology - Longview Cancer Center
state: Texas
city: Lubbock
country: United States
facility: Joe Arrington Cancer Research and Treatment Center
state: Texas
city: Midland
country: United States
facility: US Oncology - Allison Cancer Center
state: Texas
city: Odessa
country: United States
facility: US Oncology - Texas Oncology - Odessa
state: Texas
city: Plano
country: United States
facility: US Oncology - North Texas Regional Cancer Center
state: Texas
city: Plano
country: United States
facility: US Oncology - Texas Oncology Plano West Cancer Center
state: Texas
city: Round Rock
country: United States
facility: US Oncology - Texas Oncology Seton Williamson
state: Texas
city: Round Rock
country: United States
facility: US Oncology - Texas Oncology - Round Rock Cancer Center
state: Texas
city: San Antonio
country: United States
facility: US Oncology - Cancer Care Centers of South Texas
state: Texas
city: San Antonio
country: United States
facility: US Oncology - HOAST - Medical Dr.
state: Texas
city: San Antonio
country: United States
facility: US Oncology - San Antonio Tumor & Blood Clinic - M. Oak
state: Texas
city: San Marcos
country: United States
facility: US Oncology - Texas Oncology - San Marcos
state: Texas
city: Temple
country: United States
facility: Scott & White Healthcare Department of Research
state: Texas
city: Tyler
country: United States
facility: ETMC dba Blood and Cancer Center - East Texas
state: Texas
city: Tyler
country: United States
facility: ETMC dba Tyler Hematology Oncology
state: Texas
city: Waco
country: United States
facility: US Oncology - Texas Oncology Cancer Care and Research Center
state: Texas
city: Wichita Falls
country: United States
facility: US Oncology - Texoma Cancer Center
state: Texas
city: American Fork
country: United States
facility: Central Utah Clinic
state: Utah
city: Ogden
country: United States
facility: Northern Utah Associates
state: Utah
city: Salt Lake City
country: United States
facility: University of Utah - Huntsman Cancer Institute
state: Utah
city: Arlington
country: United States
facility: US Oncology - Arlington Fairfax Hematology Oncology
state: Virginia
city: Fairfax
country: United States
facility: US Oncology - Fairfax-Northern VA Hem-Onc PC
state: Virginia
city: Gainesville
country: United States
facility: US Oncology - Fairfax Northern Virginia Hematology-Oncology, PC-Gainesville
state: Virginia
city: Leesburg
country: United States
facility: US Oncology - Fairfax-Northern Virgina Hem-Onc, PC-Leesburg
state: Virginia
city: Winchester
country: United States
facility: US Oncology - Shenandoah Oncology - Winchester
state: Virginia
city: Woodbridge
country: United States
facility: US Oncology - Fairfax-Northern Virginia Hem-Onc, PC-Woodbridge
state: Virginia
city: Bellingham
country: United States
facility: Peace Health Medical Group
state: Washington
city: Edmonds
country: United States
facility: US Oncology - Puget Sound Cancer Center-Edmonds
state: Washington
city: Everett
country: United States
facility: Providence Everett Medical Center
state: Washington
city: Kennewick
country: United States
facility: Columbia Basin Hematology and Oncology
state: Washington
city: Seattle
country: United States
facility: US Oncology - Puget Sound Cancer Center-Seattle
state: Washington
city: Spokane
country: United States
facility: US Oncology - Cancer Care Northwest - Sherman
state: Washington
city: Spokane
country: United States
facility: Medical Oncology Associates PS
state: Washington
city: Walla Walla
country: United States
facility: Providence St. Mary Regional Cancer Center
state: Washington
city: Yakima
country: United States
facility: US Oncology - Yakima Valley Memorial Hospital/North Star Lodge
state: Washington
city: Morgantown
country: United States
facility: West Virginia University - Clinical Trials Research Unit
state: West Virginia
city: Appleton
country: United States
facility: Fox Valley Hematology & Oncology
state: Wisconsin
city: Green Bay
country: United States
facility: St. Vincent Hospital/Green Bay Oncology
state: Wisconsin
city: Milwaukee
country: United States
facility: CMS Water Tower Medical Commons Medical Oncology #100
state: Wisconsin
city: Waukesha
country: United States
facility: Waukesha Memorial Hospital
state: Wisconsin
city: San Juan
country: Puerto Rico
facility: Auxilio Cancer Center
Study officials:
affiliation: Bristol-Myers Squibb
name: Bristol-Myers Squibb
role: STUDY_DIRECTOR
References:
citation: Rifkin RM, Jagannath S, Durie BGM, Narang M, Terebelo HR, Gasparetto CJ, Toomey K, Hardin JW, Wagner L, Parikh K, Abouzaid S, Srinivasan S, Kitali A, Zafar F, Abonour R. Treatment Outcomes and Health Care Resource Utilization in Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide-only Maintenance, Any Maintenance, or No Maintenance: Results from the Connect MM Registry. Clin Ther. 2018 Jul;40(7):1193-1202.e1. doi: 10.1016/j.clinthera.2018.05.017. Epub 2018 Jul 23.
citation: Shah JJ, Abonour R, Gasparetto C, Hardin JW, Toomey K, Narang M, Srinivasan S, Kitali A, Zafar F, Flick ED, Rifkin RM. Analysis of Common Eligibility Criteria of Randomized Controlled Trials in Newly Diagnosed Multiple Myeloma Patients and Extrapolating Outcomes. Clin Lymphoma Myeloma Leuk. 2017 Sep;17(9):575-583.e2. doi: 10.1016/j.clml.2017.06.013. Epub 2017 Jun 17.
citation: Terebelo HR, Abonour R, Gasparetto CJ, Toomey K, Durie BGM, Hardin JW, Jagannath S, Wagner L, Narang M, Flick ED, Srinivasan S, Yue L, Kitali A, Agarwal A, Rifkin RM; CONNECT MM Registry Investigators. Development of a prognostic model for overall survival in multiple myeloma using the Connect(R) MM Patient Registry. Br J Haematol. 2019 Dec;187(5):602-614. doi: 10.1111/bjh.16139. Epub 2019 Aug 5.
citation: Rifkin RM, Abonour R, Terebelo H, Shah JJ, Gasparetto C, Hardin J, Srinivasan S, Ricafort R, Nagarwala Y, Durie BG. Connect MM Registry: The Importance of Establishing Baseline Disease Characteristics. Clin Lymphoma Myeloma Leuk. 2015 Jun;15(6):368-76. doi: 10.1016/j.clml.2014.12.002. Epub 2014 Dec 11.
citation: Rifkin RM, Abonour R, Shah JJ, Mehta J, Narang M, Terebelo H, Gasparetto C, Toomey K, Hardin JW, Lu JJ, Kenvin L, Srinivasan S, Knight R, Nagarwala Y, Durie BG. Connect MM(R) - the Multiple Myeloma Disease Registry: incidence of second primary malignancies in patients treated with lenalidomide. Leuk Lymphoma. 2016 Sep;57(9):2228-31. doi: 10.3109/10428194.2015.1132419. Epub 2016 Jan 13. No abstract available.
citation: Terebelo H, Srinivasan S, Narang M, Abonour R, Gasparetto C, Toomey K, Hardin JW, Larkins G, Kitali A, Rifkin RM, Shah JJ. Recognition of early mortality in multiple myeloma by a prediction matrix. Am J Hematol. 2017 Sep;92(9):915-923. doi: 10.1002/ajh.24796. Epub 2017 Jul 19.
citation: Jagannath S, Abonour R, Durie BGM, Gasparetto C, Hardin JW, Narang M, Terebelo HR, Toomey K, Wagner L, Srinivasan S, Kitali A, Yue L, Flick ED, Agarwal A, Rifkin RM. Heterogeneity of Second-Line Treatment for Patients With Multiple Myeloma in the Connect MM Registry (2010-2016). Clin Lymphoma Myeloma Leuk. 2018 Jul;18(7):480-485.e3. doi: 10.1016/j.clml.2018.04.007. Epub 2018 May 4.
citation: Jagannath S, Abonour R, Durie BGM, Narang M, Terebelo HR, Gasparetto CJ, Toomey K, Hardin JW, Wagner L, Agarwal A, Srinivasan S, Kitali A, Flick ED, Sturniolo M, Rifkin RM. Impact of post-ASCT maintenance therapy on outcomes in patients with newly diagnosed multiple myeloma in Connect MM. Blood Adv. 2018 Jul 10;2(13):1608-1615. doi: 10.1182/bloodadvances.2018017186.
citation: Abonour R, Wagner L, Durie BGM, Jagannath S, Narang M, Terebelo HR, Gasparetto CJ, Toomey K, Hardin JW, Kitali A, Gibson CJ, Srinivasan S, Swern AS, Rifkin RM. Impact of post-transplantation maintenance therapy on health-related quality of life in patients with multiple myeloma: data from the Connect(R) MM Registry. Ann Hematol. 2018 Dec;97(12):2425-2436. doi: 10.1007/s00277-018-3446-y. Epub 2018 Jul 29.
citation: Jagannath S, Rifkin RM, Gasparetto CJ, Toomey K, Durie BGM, Hardin JW, Terebelo HR, Wagner L, Narang M, Ailawadhi S, Omel JL, Srinivasan S, He M, Ung B, Kitali A, Flick ED, Agarwal A, Abonour R; CONNECT MM Registry Investigators. Treatment Journeys of Patients With Newly Diagnosed Multiple Myeloma (NDMM): Results From The Connect MM Registry. Clin Lymphoma Myeloma Leuk. 2020 May;20(5):272-276. doi: 10.1016/j.clml.2019.10.002. Epub 2019 Oct 14. No abstract available.
citation: Ailawadhi S, Jagannath S, Lee HC, Narang M, Rifkin RM, Terebelo HR, Durie BGM, Toomey K, Hardin JW, Gasparetto CJ, Wagner L, Omel JL, He M, Yue L, Flick ED, Agarwal A, Abonour R; Connect MM Registry Investigators. Association between race and treatment patterns and survival outcomes in multiple myeloma: A Connect MM Registry analysis. Cancer. 2020 Oct 1;126(19):4332-4340. doi: 10.1002/cncr.33089. Epub 2020 Jul 24.
citation: Abonour R, Rifkin RM, Gasparetto C, Toomey K, Durie BGM, Hardin JW, Terebelo HR, Jagannath S, Narang M, Ailawadhi S, Omel JL, Lee HC, Srinivasan S, Kitali A, Agarwal A, Wagner L; CONNECT MM Registry Investigators. Effect of initial treatment on health-related quality of life in patients with newly diagnosed multiple myeloma without immediate stem cell transplant intent: results from the Connect(R) MM Registry. Br J Haematol. 2021 Apr;193(1):93-100. doi: 10.1111/bjh.17131. Epub 2020 Oct 29.
citation: Engelhardt M, Ihorst G, Singh M, Rieth A, Saba G, Pellan M, Lebioda A. Real-World Evaluation of Health-Related Quality of Life in Patients With Multiple Myeloma From Germany. Clin Lymphoma Myeloma Leuk. 2021 Feb;21(2):e160-e175. doi: 10.1016/j.clml.2020.10.002. Epub 2020 Oct 24.
citation: Ailawadhi S, Jagannath S, Narang M, Rifkin RM, Terebelo HR, Toomey K, Durie BGM, Hardin JW, Gasparetto CJ, Wagner L, Omel JL, Kumar V, Yue L, Kitali A, Agarwal A, Abonour R; Connect MM Registry Investigators. Connect MM Registry as a national reference for United States multiple myeloma patients. Cancer Med. 2020 Jan;9(1):35-42. doi: 10.1002/cam4.2656. Epub 2019 Nov 7.