Clinical trial NCT02849756: Future of the Older Patients After Intensive Care Unit
Official title: Future of the Older Patients After Intensive Care Unit
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Intensive Care Unit Syndrome
Keywords: Intensive care
elderly
autonomy
Future
older patients
intensive care unit
Lead sponsor: Hôpital NOVO
Sponsor class: OTHER
First posted: 2016-07-29
Enrollment: 240
Sex: ALL
Minimum age (years): 85
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients older than 85 years hospitalized in intensive care unit will be included in this study.

Brief summary: Estimate the future six months after the admission in an intensive care unit of the patients of 85 and more years old in terms of autonomy.

Detailed description: The diverse studies published on the future of the elderly hospitalized in resuscitation place the limit very low, between 65 and 80 years. The feeling of a very bad forecast at these extreme ages pulls nevertheless a filter in the admission in ICU which has this day no scientific justification. The knowledge of the evolution after the hospitalization of these older patients can help to make certain decisions concerning as well the admission of these patients in ICU as the realization of invasive treatments.

After informal interrogation of numerous intensivists, it seems to take shape a bar around 85 years beyond which the forecast would be worse without more proof what consolidated the choice of this limit.

The reserved scores were already used in similar studies (simplified ALD).

Primary purpose :

* Describe the survival and the evolution of the quality of life after a stay in resuscitation for very old patients.
* The quality of life will be studied through a score of autonomy: the simplified ALD score.

The population will be described in general then by age bracket (more or less of 90 years old), according to the length of stay in ICU, the heavy treatments (artificial ventilation, renal replacement therapy) practiced, the initial gravity (score IGS 2). The impact of possible decisions of Limitation or Stop of Therapeutic Activates will also be taken into account.

Eligibility criteria: Inclusion Criteria:

* All patients over 85 years old staying in intensive car units

Exclusion Criteria:

* Knaus D
* No possibly of call (phone) 6 months after ICU admission
* Patients who do not speak French
* Patients do not accept the participation

Primary outcomes:
measure: ALD score
timeFrame: Six month
Secondary outcomes:
measure: survival
timeFrame: Six month
Other outcomes:
Locations:
city: Pontoise
country: France
facility: René-Dubos Hospital
state: Val d'Oise
Study officials:
affiliation: René-Dubos Hospital
name: Philippe Dr MICHEL, PH
role: PRINCIPAL_INVESTIGATOR
References:
citation: Khouli H, Astua A, Dombrowski W, Ahmad F, Homel P, Shapiro J, Singh J, Nallamothu R, Mahbub H, Eden E, Delfiner J. Changes in health-related quality of life and factors predicting long-term outcomes in older adults admitted to intensive care units. Crit Care Med. 2011 Apr;39(4):731-7. doi: 10.1097/CCM.0b013e318208edf8.
citation: Lewis-Newby M, Curtis JR, Martin DP, Engelberg RA. Measuring family satisfaction with care and quality of dying in the intensive care unit: does patient age matter? J Palliat Med. 2011 Dec;14(12):1284-90. doi: 10.1089/jpm.2011.0138. Epub 2011 Nov 22.
citation: Biston P, Aldecoa C, Devriendt J, Madl C, Chochrad D, Vincent JL, De Backer D. Outcome of elderly patients with circulatory failure. Intensive Care Med. 2014 Jan;40(1):50-6. doi: 10.1007/s00134-013-3121-7. Epub 2013 Oct 17.