Clinical trial NCT02018848: Internet-delivered Attention Training for Obsessive-Compulsive Disorder
Official title: Internet-delivered Attention Training for Obsessive-Compulsive Disorder
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Obsessive-Compulsive Disorder
Keywords: Obsessive-Compulsive Disorder
Attention Training
Attention Bias Modification
Dot-Probe Task
Randomized Controlled Trial
Online Treatment
Washing
Checking
Lead sponsor: Humboldt-Universität zu Berlin
Sponsor class: OTHER
First posted: 2013-12-23
Enrollment: 108
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this study is to investigate an attention training program for participants with Obsessive-Compulsive Disorder. The attention training consists of a modified dot probe task with picture stimuli related to washing and checking paired with neutral pictures.

Participants are randomly assigned to an experimental and a placebo-control group. After a minimum of 4 weeks of attention training we expect to find differences between participants of the experimental and the control group in terms of attention bias, OCD symptoms, anxiety and depression.


Eligibility criteria: Inclusion Criteria:

* diagnosis of primary OCD according to OCI-R self report (cut-off \>=18)

Exclusion Criteria:

* suicidal
* substance abuse or addiction
* psychotic symptoms
* visual impairment if not compensated with optical aid

Current treatment is not an exclusion criterion, but data on treatment status (current psycho- or pharmacotherapy for OCD) will enter our statistical analyses.

Primary outcomes:
measure: Yale-Brown Obsessive-Compulsive Scale Self-Report Scale (Y-BOCS-SRS) T1
timeFrame: pre-treatment, estimated: between day 1 and day 7 after enrolment (no time limit set)
measure: Yale-Brown Obsessive-Compulsive Scale Self-Report Scale (Y-BOCS-SRS) T2
timeFrame: post-treatment, between day 1 and 6 after T2 Bias Assessment (time limit set)
measure: Yale-Brown Obsessive-Compulsive Scale Self-Report Scale (Y-BOCS-SRS) T3
timeFrame: follow-up, between day 27 and 50 after T2 questionnaires (time limit set)
Secondary outcomes:
measure: Obsessive-Compulsive Inventory-Revised (OCI-R) T1
timeFrame: pre-treatment, estimated: between day 1 and day 7 after enrolment (no time limit set)
measure: Obsessive-Compulsive Inventory-Revised (OCI-R) T2
timeFrame: post-treatment, between day 1 and 6 after T2 Bias Assessment (time limit set)
measure: Obsessive-Compulsive Inventory-Revised (OCI-R) T3
timeFrame: follow-up, between day 27 and 50 after T2 questionnaires (time limit set)
Other outcomes:
measure: Beck Anxiety Inventory (BAI) T1
timeFrame: pre-treatment, estimated: between day 1 and day 7 after enrolment (no time limit set, all further steps relative to exact time point of T1 questionnaires)
measure: Beck Anxiety Inventory (BAI) T2
timeFrame: post-treatment, between day 1 and 6 after T2 Bias Assessment (time limit set)
measure: Beck Anxiety Inventory (BAI) T3
timeFrame: follow-up, between day 27 and 50 after T2 questionnaires (time limit set)
measure: Beck Depression Inventory II (BDI-II) T1
timeFrame: pre-treatment, estimated: between day 1 and day 7 after enrolment (no time limit set, all further steps relative to exact time point of T1 questionnaires)
measure: Beck Depression Inventory II (BDI-II) T2
timeFrame: post-treatment, between day 1 and 6 after T2 Bias Assessment (time limit set)
measure: Beck Depression Inventory II (BDI-II) T3
timeFrame: follow-up, between day 27 and 50 after T2 questionnaires (time limit set)
measure: Attention bias towards OCD-relevant stimuli at T1 measured with a dot-probe task.
timeFrame: after T1 questionnaires and pre-treatment, estimated: between day 1 and 3 after T1 questionnaires (no time limit set)
measure: Attention bias towards OCD-relevant stimuli at T2 measured with a dot-probe task.
timeFrame: post-treatment, after a minimum of 8 training sessions over a time of 4 weeks, estimated: between day 1 and 4 after last training session (no time limit set)
Locations:
city: Berlin
country: Germany
facility: Humboldt-Universität zu Berlin
Study officials:
References: