Clinical trial NCT05244356: Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation
Official title: Effective Public Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation: A Randomized Controlled Experiment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: COVID-19
Respiratory Disease
Vaccine Refusal
Infectious Disease
Coronavirus Infections
Behavior, Health
Pneumonia
Respiratory Tract Infections
Lung Diseases
Pneumonia, Viral
Keywords: message
messaging
propagation
intent
vaccine
recommend
Lead sponsor: Clinical Research Centre, Malaysia
Sponsor class: OTHER
Collaborators: name: Institute for Health Behavioral Research, Malaysia
name: University of Malaya
name: UNICEF Malaysia
name: Ministry of Health, Malaysia
name: London School of Economics and Political Science
First posted: 2022-02-17
Enrollment: 5784
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: This is a randomised controlled experiment in the form of a web based survey study which randomly exposes participants to different forms of public health messages, after which participants will be assessed on their intent to take up the COVID-19 vaccine, recommend the vaccine, and also willingness to propagate the exposed message.


Eligibility criteria: Inclusion Criteria:

* Willing and able to give informed consent for participation in the trial
* Malaysian nationality.
* Can understand either the English or Malay language.
* Aged 18 years or above

Exclusion Criteria:

* Received at least one COVID-19 vaccination dose

Primary outcomes:
measure: Change in intent to accept the COVID-19 vaccine amongst the Malaysian adult population.
timeFrame: Immediately before and after message exposure during questionnaire administration.
measure: Change in intent to recommend the COVID-19 vaccine to healthy adults.
timeFrame: Immediately before and after message exposure during questionnaire administration.
measure: Change in intent to recommend the COVID-19 vaccine to elderly.
timeFrame: Immediately before and after message exposure during questionnaire administration.
measure: Change in intent to recommend the COVID-19 vaccine to people with existing health conditions.
timeFrame: Immediately before and after message exposure during questionnaire administration.
measure: Intent to share message on social media platform.
timeFrame: Immediately after message exposure during questionnaire administration.
Secondary outcomes:
measure: Moderators of vaccination intent.
timeFrame: Immediately after message exposure during questionnaire administration.
measure: Reliability of various information sources about COVID-19.
timeFrame: Immediately after message exposure during questionnaire administration.
Other outcomes:
Locations:
city: Shah Alam
country: Malaysia
facility: Institute for Clinical Research, National Institutes of Health, Malaysia
state: Selangor
Study officials:
affiliation: Clinical Research Centre, Malaysia
name: Yee Liang Hing, MSc.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Hing NYL, Woon YL, Lee YK, Kim HJ, Lothfi NM, Wong E, Perialathan K, Ahmad Sanusi NH, Isa A, Leong CT, Costa-Font J. When do persuasive messages on vaccine safety steer COVID-19 vaccine acceptance and recommendations? Behavioural insights from a randomised controlled experiment in Malaysia. BMJ Glob Health. 2022 Jul;7(7):e009250. doi: 10.1136/bmjgh-2022-009250.