Clinical trial NCT06279988: BRING-UP 3 Heart Failure
Official title: BRING-UP 3 Heart Failure
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Heart Failure
Lead sponsor: Heart Care Foundation
Sponsor class: OTHER
First posted: 2024-02-28
Enrollment: 10000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All consecutive patients with chronic HF and those admitted for acute (de novo or worsening) HF.

Brief summary: The aim of this observational study is to assess the level of adherence to guideline recommendations regarding the management of patients with Heart Failure with Reduced Ejection Fraction (HFrEF); - the safety profile of the implementation of recommended treatments; - to monitor treatment patterns of patients with acute hert failure (HF); - to monitor treatment patterns of all patients with chronic HF irrespective of the level of ejection fraction (EF).

Detailed description: Observational, prospective, multicenter study conducted in a large, representative sample of Italian cardiology centers.

Phases 1:

1. First educational intervention to discuss the recommendations of guidelines and treatment patterns in specific phenotypes of patients.
2. Data collection for 3 months or up to 30 consecutive patients with chronic HF or acute HF (both de novo and worsening).
3. Evaluation of the primary and secondary end-points of the study at 6 months after enrollment. Modifications of treatments will be monitored during the 6 months follow-up.
4. Second educational intervention to share the results of the first enrollment period of the study focusing the attention on existing gaps between guidelines recommendations and clinical practice.
5. New data collection for other 3 months or up to 30 consecutive patients with chronic HF or acute HF (both de novo and worsening).
6. Additional evaluation of the primary and secondary end-points of the study at 6 months after enrollment. Modifications of treatments will be monitored during the 6 months follow-up.
7. 12-month follow-up for all patients included in both enrolment phases of the study.

Eligibility criteria: Inclusion Criteria:

1. Age ≥18 years old.
2. Males and females at birth.
3. Any ejection fraction level (level of ejection fraction measured in the 6 months preceding enrollment).
4. Ambulatory chronic HF or Hospitalized de-novo or worsening HF.
5. Signed informed consent

Diagnosis will be made by the local attending physician following the ESC guidelines recommendations.

Exclusion Criteria:

1. Active neoplasia or very severe disease compromising short-medium term life expectancy.
2. Participation in interventional studies.
3. Patients already enrolled into the study from another participating center or in the previous enrolling phase.

Primary outcomes:
measure: Rate of adherence to Guideline-Directed Medical Therapy (GDMTs) in HFrEF
timeFrame: 6 months
Secondary outcomes:
measure: Rate of patient achieving appropriate dosages of GDMTs
timeFrame: 6 months
measure: Treatment patterns of patients with Heart failure with mildly reduced ejection fraction (HFmrEF) and Heart failure with preserved ejection fraction (HFpEF)
timeFrame: 6 months
measure: Treatment patterns of patients with Acute Heart Failure (AHF) irrespective of the level of EF
timeFrame: 6 months
measure: All cause and specific causes of death and hospitalization (Exploratory endpoint)
timeFrame: 12 months
Other outcomes:
Locations:
city: Casale Monferrato
country: Italy
facility: Ospedale Santo Spirito - Sc Cardiologia
state: AL
city: Novi Ligure
country: Italy
facility: Ospedale San Giacomo - Sc Cardiologia
state: AL
city: Ancona
country: Italy
facility: Ospedali Riuniti - Sod Cardiologia Ospedaliera E Utic
state: AN
city: Ancona
country: Italy
facility: Irccs Inrca - Uo Cardiologia/Utic/Telecardiologia
state: AN
city: Arezzo
country: Italy
facility: Ospedale San Donato - U.O.C Cardiologia
state: AR
city: Cortona
country: Italy
facility: Ospedale Valdichiana Santa Margherita - Uosd Cardiologia S.O. Cortona
state: AR
city: Avellino
country: Italy
facility: Aorn San Giuseppe Moscati - U.O. Cardiologia/Utic 'D. Rotiroti'
state: AV
city: Acquaviva Delle Fonti
country: Italy
facility: Ospedale Miulli - U.O.C. Cardiologia - Utic
state: BA
city: Altamura
country: Italy
facility: Ospedale Della Murgia - Fabio Perinei - S.C. Cardiologia-Utic
state: BA
city: Bari
country: Italy
facility: Ospedale San Paolo - Cardiologia-Utic
state: BA
city: Bari
country: Italy
facility: Ics Maugeri Spa Societa' Benefit Irccs Bari - Cardiologia Riabilitativa
state: BA
city: Bari
country: Italy
facility: Mater Dei Hospital - Riabilitazione Cardiologica
state: BA
city: Carbonara Di Bari
country: Italy
facility: Ospedale Di Venere - U.O.C. Di Cardiologia
state: BA
city: Monopoli
country: Italy
facility: Ospedale San Giacomo - Uoc Cardiologia
state: BA
city: Ponderano
country: Italy
facility: Ospedale Degli Infermi - Sc Di Cardiologia
state: BI
city: Feltre
country: Italy
facility: Presidio Ospedaliero "Santa Maria Del Prato" - U.O.C. Di Cardiologia-Utic
state: BL
city: Bentivoglio
country: Italy
facility: Ospedale Di Bentivoglio - U.O. Cardiologia Pianura
state: BO
city: Bologna
country: Italy
facility: Ospedale Maggiore - U.O.C. Di Cardiologia
state: BO
city: Bologna
country: Italy
facility: Ospedale Policlinico S. Orsola-Malpighi - Medicina Interna - Borghi
state: BO
city: Brindisi
country: Italy
facility: Ospedale Perrino - U.O.C. Di Cardiologia
state: BR
city: Brescia
country: Italy
facility: Istituto Ospedaliero Fondazione Poliambulanza - Unita Operativa Di Cardiologia E Utic
state: BS
city: Desenzano Del Garda
country: Italy
facility: Ospedale Di Desenzano Del Garda - Divisione Di Cardiologia - U.C.C.
state: BS
city: Gavardo
country: Italy
facility: Ospedale Civile 'La Memoria' - U.O. Di Cardiologia
state: BS
city: Lumezzane
country: Italy
facility: Istituti Clinici Scientifici Maugeri Irccs Sede Di Lumezzane - U.O. Di Cardiologia Riabilitativa
state: BS
city: Barletta
country: Italy
facility: Ospedale Monsignor Angelo R. Di Miccoli - Uoc Cardiologia/Utic
state: BT
city: Canosa Di Puglia
country: Italy
facility: Ospedale Caduti in Guerra - U.O.S.V.D Di Riabilitazione Cardiologica
state: BT
city: Bolzano
country: Italy
facility: Ospedale Centrale Bolzano - Cardiologia E Prove Funzionali
state: BZ
city: Caserta
country: Italy
facility: Azienda Ospedaliera S. Anna E S. Sebastiano - U.O. Cardiologia D'Emergenza Con Utic
state: CE
city: Castel Morrone
country: Italy
facility: Villa Delle Magnolie - Riabilitazione Cardiologica
state: CE
city: Maddaloni
country: Italy
facility: Casa Di Cura San Michele - Uo Cardiologia
state: CE
city: Chieti
country: Italy
facility: Ospedale Policlinico Ss. Annunziata - Uoc Cardiologia-Utic
state: CH
city: Cuneo
country: Italy
facility: Azienda Ospedaliera Santa Croce E Carle - Sc Cardiologia
state: CN
city: Mondovì
country: Italy
facility: Ospedale Regina Montis Regalis - U.O. Cardiologia-Utic
state: CN
city: Savigliano
country: Italy
facility: Ospedale Maggiore Ss. Annunziata - Sc Cardiologia
state: CN
city: Verduno
country: Italy
facility: Ospedale Pietro E Michele Ferrero - Cardiologia E Utic
state: CN
city: San Fermo Della Battaglia
country: Italy
facility: Ospedale S. Anna - U.O.C. Di Cardiologia
state: CO
city: Casalmaggiore
country: Italy
facility: Ospedale Oglio Po - U.O. Di Cardiologia-Utic
state: CR
city: Castrovillari
country: Italy
facility: Ospedale Civile Ferrari - U.O.C. Cardiologia-Utic
state: CS
city: Paola
country: Italy
facility: Ospedale Spoke Paola- Cetraro Po Paola - Utic Cardiologia
state: CS
city: Catania
country: Italy
facility: P.O. Garibaldi-Nesima - Arnas Garibaldi - U.O.C. Di Cardiologia Con Utic
state: CT
city: Catania
country: Italy
facility: Policlinico Catania Po G. Rodolico - Cardiologia Utic
state: CT
city: Catania
country: Italy
facility: Azienda Ospedaliera Cannizzaro - Uoc Cardiologia
state: CT
city: Catanzaro
country: Italy
facility: P.O. "Materdomini" - A.O.U. "Renato Dulbecco" - Ssd Cardiologia Riabilitativa
state: CZ
city: Catanzaro
country: Italy
facility: P.O. "Pugliese" - A.O.U. "Renato Dulbecco" - Utic-Emodinamica E Cardiologia Interventistica
state: CZ
city: Enna
country: Italy
facility: Presidio Ospedaliero Umberto I - Cardiologia - Utic- Riabilitazione
state: EN
city: Forli'
country: Italy
facility: Ospedale G.B. Morgagni - L. Pierantoni - U.O. Cardiologia
state: FC
city: Cento
country: Italy
facility: Ospedale Ss. Annunziata - U.O. Di Cardiologia Provinciale
state: FE
city: Ferrara
country: Italy
facility: Arcispedale Sant'Anna - U.O. Cardiologia
state: FE
city: Lagosanto
country: Italy
facility: Ospedale Del Delta - U.O. Cardiologia
state: FE
city: Foggia
country: Italy
facility: Policlinico Riuniti - S.C. Di Cardiologia Universitaria-Utic
state: FG
city: San Giovanni Rotondo
country: Italy
facility: Ospedale Casa Sollievo Della Sofferenza - Cardiologia - Utic - Riabil Cardiologica
state: FG
city: Empoli
country: Italy
facility: Ospedale San Giuseppe - Cardiologia
state: FI
city: Firenze
country: Italy
facility: Ospedale Santa Maria Nuova - Cardiologia
state: FI
city: Firenze
country: Italy
facility: Ospedale San Giovanni Di Dio - Sos Cardiologia
state: FI
city: Firenze
country: Italy
facility: Aou Careggi - Geriatria - Utig
state: FI
city: Genova
country: Italy
facility: Ospedale Padre Antero Micone - Sc Cardiologia - Utic
state: GE
city: Genova
country: Italy
facility: Irccs Ospedale Policlinico San Martino - Clinica Malattie Apparato Cardiovascolare
state: GE
city: Lavagna
country: Italy
facility: Ospedale Del Tigullio Polo Lavagna - Sc Cardiologia E Utic
state: GE
city: Gorizia
country: Italy
facility: Ospedale San Giovanni Di Dio - Sc Cardiologia (Gorizia-Monfalcone)
state: GO
city: Monfalcone
country: Italy
facility: Ospedale Civile San Polo - Sc Cardiologia (Gorizia-Monfalcone)
state: GO
city: Massa Marittima
country: Italy
facility: Ospedale S. Andrea - Alta Maremma - Uosd Cardiologia
state: GR
city: Lecco
country: Italy
facility: Ospedale Alessandro Manzoni - S.C. Di Cardiologia
state: LC
city: Copertino
country: Italy
facility: Ospedale San Giuseppe Da Copertino - U.O. Di Cardiologia
state: LE
city: Lecce
country: Italy
facility: Ospedale Vito Fazzi - Uoc Cardiologia-Utic Ed Emodinamica
state: LE
city: Scorrano
country: Italy
facility: Ospedale Ignazio Veris Delli Ponti - Uoc Cardiologia-Utic "E. Vilei"
state: LE
city: Livorno
country: Italy
facility: Ospedali Riuniti - U.O.C. Cardiologia E Utic
state: LI
city: Piombino
country: Italy
facility: Ospedale Villamarina - Cardiologia E Utic Piombino Elba
state: LI
city: Camaiore
country: Italy
facility: Nuovo Ospedale Versilia - Sc Cardiologia
state: LU
city: Castelnuovo Di Garfagnana
country: Italy
facility: Ospedale Santa Croce - Uosd Cardiologia E Di Continuita Assist.
state: LU
city: Desio
country: Italy
facility: Ospedale Pio Xi - U.O.C. Di Cardiologia
state: MB
city: Monza
country: Italy
facility: Policlinico Di Monza - Cardiologia Clinica E Utic
state: MB
city: Vimercate
country: Italy
facility: Nuovo Ospedale Di Vimercate - S.C. Cardiologia E Utic
state: MB
city: Macerata
country: Italy
facility: Ospedale Generale Provinciale - U.O. Cardiologia
state: MC
city: Messina
country: Italy
facility: Irccs Centro Neurolesi Bonino Pulejo - P.O Piemonte - Cardiologia E Utic
state: ME
city: Messina
country: Italy
facility: Azienda Ospedaliera Papardo - U.O. Cardiologia Con Utic - Emodinamica
state: ME
city: Bergamo
country: Italy
facility: Asst Papa Giovanni Xxiii - Sc Cardiologia 1
state: MI
city: Cernusco Sul Naviglio
country: Italy
facility: Ospedale Di Cernusco Sul Naviglio - U. O. Di Cardiologia E Ucc
state: MI
city: Cinisello Balsamo
country: Italy
facility: Ospedale Edoardo Bassini - Sc Cardiologia-Ucc Asst Nord Milano (Bassini-Ssg)
state: MI
city: Legnano
country: Italy
facility: Asst Ovest Milanese - Po Di Legnano - Cardiologia E Unita' Coronarica
state: MI
city: Milano
country: Italy
facility: Fondazione Irccs Ca' Granda Ospedale Maggiore Policlinico - Uoc Malattie Cardiovascolari
state: MI
city: Milano
country: Italy
facility: Ospedale Fatebenefratelli E Oftalmico - Cardiologia E U.C.C.
state: MI
city: Milano
country: Italy
facility: Centro Cardiologico Monzino Irccs - Scompenso,Cardiologia Clinica
state: MI
city: Milano
country: Italy
facility: Istituti Clinici Scientifici Maugeri Irccs Sede Di Milano - Riabilitazione Cardiologica
state: MI
city: Milano
country: Italy
facility: Istituti Clinici Scientifici Maugeri Irccs Sede Di Milano - Uo Cure Subacute
state: MI
city: Milano
country: Italy
facility: ASST SANTI PAOLO E CARLO - PO San Carlo - CARDIOLOGIA-UCC
state: MI
city: Milano
country: Italy
facility: Irccs Ospedale Galeazzi - Sant'Ambrogio - Cardiologia Universitaria Ed Imaging Cardiaco
state: MI
city: Milano
country: Italy
facility: Asst Ospedale Metropolitano Niguarda - Cardiologia 2 - Insufficienza Cardiaca E Trapianto
state: MI
city: Paderno Dugnano
country: Italy
facility: Clinica San Carlo - U.O. Cardiologia-Unita'Cure Coronariche
state: MI
city: Passirana
country: Italy
facility: Presidio Ospedaliero Di Passirana - Cardiologia Riabilitativa
state: MI
city: Rozzano
country: Italy
facility: Istituto Clinico Humanitas - Irccs - Cardiologia Clinica, Interventistica E Ucc
state: MI
city: San Donato Milanese
country: Italy
facility: Irccs Policlinico San Donato - U.O. Cardiologia Con Utic
state: MI
city: Sesto San Giovanni
country: Italy
facility: Irccs Policlinico Multimedica - Uo Di Cardiologia
state: MI
city: Matera
country: Italy
facility: Ospedale Madonna Delle Grazie - Ssd Utic
state: Mount
city: Policoro
country: Italy
facility: Ospedale Giovanni Paolo Ii - Uosd Utic
state: Mount
city: Mirandola
country: Italy
facility: Ospedale Santa Maria Bianca - U.O. Di Cardiologia
state: MO
city: Sassuolo
country: Italy
facility: Ospedale Di Sassuolo - Cardiologia
state: MO
city: Olbia
country: Italy
facility: Ospedale Giovanni Paolo Ii - Utic - Cardiologia
state: OT
city: Cefalu'
country: Italy
facility: Fondazione G. Giglio - U.O. Di Cardiologia
state: PA
city: Palermo
country: Italy
facility: Ospedale Buccheri La Ferla Fatebenefratelli - Ssd Riabilitazione Cardiovascolare
state: PA
city: Palermo
country: Italy
facility: Arnas P.O. Civico E Benfratelli - Uoc Utic
state: PA
city: Palermo
country: Italy
facility: Arnas P.O. Civico E Benfratelli - Uosd Cardiologia Clinica Trattam. Scompenso Card.
state: PA
city: Palermo
country: Italy
facility: Maria Eleonora Hospital - Cardiologia
state: PA
city: Palermo
country: Italy
facility: Aor Villa Sofia-Cervello P.O. Cervello - U.O. Cardiologia - Cervello
state: PA
city: Palermo
country: Italy
facility: Aor Villa Sofia-Cervello Po Villa Sofia - Uoc Cardiologia E Utic E Emodinamica -Villa Sofia
state: PA
city: Castel San Giovanni
country: Italy
facility: Ospedale Unico Della Val Tidone - Cardiologia E Riabilitazione
state: PC
city: Piacenza
country: Italy
facility: Ospedale Civile 'Guglielmo Da Saliceto' - Uoc Cardiologia E Utic
state: PC
city: Monselice
country: Italy
facility: Ospedali Riuniti Padova Sud - U.O.C. Cardiologia
state: PD
city: Pescara
country: Italy
facility: Ospedale Civile Dello Spirito Santo - Cardiologia Con Utic
state: PE
city: Citta' Di Castello
country: Italy
facility: Presidio Ospedaliero Citta' Di Castello - U.O. Cardiologia/Utic
state: PG
city: Foligno
country: Italy
facility: Nuovo Ospedale San Giovanni Battista - S.C. Cardiologia
state: PG
city: Gubbio
country: Italy
facility: Ospedale Gubbio-Gualdo Tadino - U.O. Di Utic E Cardiologia
state: PG
city: Perugia
country: Italy
facility: Centro Servizi Grocco - Cardiologia Riabilitativa E Prevenzione
state: PG
city: Pisa
country: Italy
facility: Ftgm - Stabilimento Di Pisa - Cardiologia E Medicina Cardiovascolare
state: PI
city: Pontedera
country: Italy
facility: Ospedale Generale Provinciale Lotti - U.O. Malattie Cardiovascolari Vde E Avc
state: PI
city: San Vito Al Tagliamento
country: Italy
facility: Ospedale Di S. Vito Al Tagliamento - Ssd Cardiologia San Vito - Spilimbergo
state: PN
city: Pistoia
country: Italy
facility: Ospedale San Jacopo - Soc Cardiologia
state: Point
city: Fidenza
country: Italy
facility: Ospedale Civile - U.O.C. Cardiologia - Utic
state: PR
city: Pavia
country: Italy
facility: Fondazione Irccs Policlinico San Matteo - Uoc Cardiologia 1
state: PV
city: Pavia
country: Italy
facility: Istituti Clinici Scientifici Maugeri Irccs Sede Di Pavia - U.O. Di Riabilitazione Cardiologica
state: PV
city: Voghera
country: Italy
facility: Ospedale Civile - U.O. Di Cardiologia
state: PV
city: Lugo
country: Italy
facility: Ospedale Civile - Uo Servizio Cardiologia
state: RA
city: Ravenna
country: Italy
facility: Ospedale Civile Santa Maria Delle Croci - Uoc Cardiologia
state: RA
city: Guastalla
country: Italy
facility: Ospedale Civile Di Guastalla - Sos Cardiologia E Riabilitazione Card Area Nord
state: RE
city: Reggio Emilia
country: Italy
facility: Po Santa Maria Nuova - Ausl Re Irccs - Soc Cardiologia Ospedaliera
state: RE
city: Vittoria
country: Italy
facility: Ospedale Riccardo Guzzardi - U.O.C. Di Cardiologia-Utic
state: RG
city: Rieti
country: Italy
facility: P.O. San Camillo de Lellis - U.O.C. Cardiologia
state: RI
city: Ariccia
country: Italy
facility: Ospedale Dei Castelli - U.O.C. Di Cardiologia E Utic
state: RM
city: Civitavecchia
country: Italy
facility: Ospedale Civile San Paolo - U.O.C. Cardiologia - Utic
state: RM
city: Roma
country: Italy
facility: Campus Biomedico - Cardiologia
state: RM
city: Roma
country: Italy
facility: P.O. San Filippo Neri - Asl Roma 1 - Cardiologia Clinica E Riabilitativa
state: RM
city: Roma
country: Italy
facility: Inmi Lazzaro Spallanzani Irccs - Servizio Di Cardiologia Del Dipartimento Clinico
state: RM
city: Roma
country: Italy
facility: Ospedale San Camillo - Uoc Cardiologia
state: RM
city: Roma
country: Italy
facility: Ospedale Sandro Pertini - Uoc Cardiologia
state: RM
city: Roma
country: Italy
facility: Policlinico Casilino - U.O.C. Cardiologia
state: RM
city: Roma
country: Italy
facility: Ao San Giovanni Addolorata - Uoc Cardiologia D'Urgenza E Utic
state: RM
city: Roma
country: Italy
facility: Ospedale Isola Tiberina - Uoc Cardiologia Diagnostica Interventistica-Utic
state: RM
city: Roma
country: Italy
facility: Ospedale Sant'Andrea Di Roma - U.O.C. Cardiologia
state: RM
city: Roma
country: Italy
facility: Ospedale Santo Spirito - Uoc Cardiologia
state: RM
city: Tivoli
country: Italy
facility: Ospedale San Giovanni Evangelista - U.O.C. Di Cardiologia - Utic
state: RM
city: Rimini
country: Italy
facility: Ospedale Infermi - U.O. Cardiologia
state: RN
city: Eboli
country: Italy
facility: Ospedale Maria Ss. Addolorata - U.O. Di Cardiologia Utic
state: SA
city: Salerno
country: Italy
facility: Aou S. Giovanni Di Dio-Ruggi D'Aragona - Cardiologia Intensiva Ospedaliera
state: SA
city: Salerno
country: Italy
facility: Aou S. Giovanni Di Dio-Ruggi D'Aragona - Ssd Utic
state: SA
city: Vallo Della Lucania
country: Italy
facility: Ospedale San Luca - U.O. Utic - Cardiologia
state: SA
city: Poggibonsi
country: Italy
facility: Ospedale Dell'Alta Val D'Elsa - Uosd Cardiologia-Utic
state: SI
city: Siena
country: Italy
facility: Aou Senese Ospedale S. Maria Alle Scotte - Cardiologia
state: SI
city: Sarzana
country: Italy
facility: Ospedale San Bartolomeo - Sc Riabilitazione Cardiologica
state: SP
city: Augusta
country: Italy
facility: Ospedale E. Muscatello - U.O. Di Cardiologia - Utic
state: SR
city: Avola
country: Italy
facility: Ospedale G. Di Maria - Cardiologia Utic
state: SR
city: Sassari
country: Italy
facility: Ospedale Ss. Annunziata - Cardiologia Clinica Ed Interventistica
state: SS
city: San Gavino Monreale
country: Italy
facility: Ospedale Nostra Signora Di Bonaria - U.O.C. Cardiologia E Utic
state: SU
city: Pietra Ligure
country: Italy
facility: Po Ponente - Ospedale Santa Corona - Sc Cardiologia Ponente
state: SV
city: Savona
country: Italy
facility: P.O. Levante - Ospedale San Paolo - S.C. Cardiologia Levante
state: SV
city: Taranto
country: Italy
facility: Casa Di Cura Villa Verde - Cardiologia
state: TA
city: Trento
country: Italy
facility: Ospedale Santa Chiara - Divisione Di Cardiologia
state: TN
city: Chivasso
country: Italy
facility: Ospedale Civico - Sc Cardiologia
state: TO
city: Cirié
country: Italy
facility: Por Cirié- Lanzo Presidio Cirié - S.C. Cardiologia
state: TO
city: Ivrea
country: Italy
facility: Ospedale Civile - S.C. Cardiologia
state: TO
city: Orbassano
country: Italy
facility: Aou San Luigi Gonzaga - S.C.D.O. Cardiologia
state: TO
city: Torino
country: Italy
facility: Aou Citta' Della Salute E Della Scienza - S.C. Cardiologia U
state: TO
city: Torino
country: Italy
facility: Ospedale Martini - Cardiologia (Mrt-Mv)
state: TO
city: Torino
country: Italy
facility: Ospedale Maria Vittoria - Cardiologia (Mrt-Mv)
state: To
city: Torino
country: Italy
facility: Ospedale San Giovanni Bosco - Sc Cardiologia
state: TO
city: Rovereto
country: Italy
facility: Ospedale Santa Maria Del Carmine - Cardiologia
state: Trento
city: Trieste
country: Italy
facility: Asugi Trieste - Sc Patologie Cardiovascolari
state: TS
city: Udine
country: Italy
facility: Pou "Santa Maria Della Misericordia" - S.O.C. Cardiologia
state: UD
city: Castellanza
country: Italy
facility: Ospedale Multimedica Castellanza - Cardiologia
state: VA
city: Saronno
country: Italy
facility: Presidio Ospedaliero Di Saronno - U.O.C. Di Cardiologia
state: VA
city: Tradate
country: Italy
facility: Ospedale Di Circolo Galmarini - Cardiologia
state: VA
city: Vercelli
country: Italy
facility: Ospedale Sant'Andrea - Sc Cardiologia
state: VC
city: Mestre
country: Italy
facility: Ospedale Dell'Angelo - U.O.C. Cardiologia
state: VE
city: Noale
country: Italy
facility: Ospedale P.F. Calvi - Uos Di Cardiologia Riabilitativa
state: VE
city: Arzignano
country: Italy
facility: Ospedale Civile - U.O.C. Di Cardiologia
state: VI
city: Santorso
country: Italy
facility: Ospedale Alto Vicentino - U.O.C. Cardiologia - Ucic
state: VI
city: San Bonifacio
country: Italy
facility: Ospedale G. Fracastoro - U.O.C. Di Cardiologia
state: VR
city: Civita Castellana
country: Italy
facility: Ospedale Civita Castellana - Ssd Cardiologia
state: VT
city: Viterbo
country: Italy
facility: Ospedale Belcolle - Uoc Cardiologia Ed Emodinamica
state: VT
city: Borgomanero
country: Italy
facility: Ospedale Ss. Trinita' - S.C. Di Cardiologia
city: Gattico
country: Italy
facility: Istituti Clinici Scientifici Maugeri Irccs Sede Di Veruno - Uo Cardiologia Riabilitativa
city: Lacco Ameno
country: Italy
facility: Ospedale Anna Rizzoli - Cardiologia-Utic
city: Napoli
country: Italy
facility: Ospedale Buon Consiglio Fatebenefratelli - U.O.Complessa Di Cardiologia E Utic
city: Napoli
country: Italy
facility: Aorn Cardarelli - U.O. Cardiologia Con Utic
city: Napoli
country: Italy
facility: Aorn Ospedale Dei Colli - P.O. Monaldi - Uosd Card. Riabilitativa Intensiva E Scompenso
city: Napoli
country: Italy
facility: Aorn Ospedale Dei Colli - P.O. Monaldi - Uosd Malattie Cardiologiche Congenite Adulti-Guch
city: Napoli
country: Italy
facility: Ospedale S. Giovanni Bosco - Sc Cardiologia - Utic
city: Novara
country: Italy
facility: Aou Maggiore Della Carita' - Scdo Cardiologia Ii
city: Pozzuoli
country: Italy
facility: Ospedale Santa Maria Delle Grazie - U.O. Cardiologia - Utic Con Emodinamica
Study officials:
References: