Clinical trial NCT04960007: Comparison of the Swallowing Functions in Sarcopenia and Dynapenia
Official title: Comparison of the Swallowing Functions of the Sarcopenia and Dynapenia Patients
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Sarcopenia
Dysphagia
Swallowing Disorder
Keywords: sarcopenia
dynapenia
swallowing
deglutition
dysphagia
Lead sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Sponsor class: OTHER
First posted: 2021-07-13
Enrollment: 108
Sex: ALL
Minimum age (years): 60
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients who were 60-90 years old.

Brief summary: The purpose of the study to investigate the comparison of the swallowing functions of the sarcopenia and dynapenia in older patients

Detailed description: Sarcopenia is a geriatric syndrome; from skeletal muscle, and in its usefulness. Dynapenia is a picture of sarcopenia without measurable muscle mass. It has been shown that dysphagia complaints are more common in patients with sarcopenia than in the normal population, but a comparison with patients with dynapenia has not been made to the best of our knowledge. According to the algorithm of The International Society of Physical and Rehabilitation Medicine (ISPRM), experts in the special interest group on sarcopenia, in the routine examination of patients aged 60-90 years who applied to the Physical Medicine and Rehabilitation outpatient clinic with complaints of decreased muscle function, weakness, and slow movement, or "sarcopenia" or Patients with "dynapenia" and patients without Sarcopenia disease who volunteered to participate in the study will be included in the order of application to the outpatient clinic.

Eligibility criteria: Inclusion Criteria:

* Age between 60-90 years
* Sarcopenia and dynapenia patients in study groups
* Non- sarcopenia and non-dynapenia patients in control groups
* Patients who were accept to consent form

Exclusion Criteria:

* Severe sarcopenia patients
* Cognitive limitations
* Out of age 60-90 years old
* Patients who were not accept to consent form

Primary outcomes:
measure: The values of Pharyngeal Residue Severity
timeFrame: Baseline
measure: The values of penetration and aspiration
timeFrame: Baseline
measure: The evaluation of eating and swallowing functions
timeFrame: Baseline
measure: The evaluation of depression
timeFrame: Baseline
measure: The values of muscle strength
timeFrame: Baseline
measure: The values of muscle mass
timeFrame: Baseline
Secondary outcomes:
measure: Mean of demographic
timeFrame: Baseline
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Prof Dr Cemil Tascioglu City Hospital
Study officials:
affiliation: Prof. Dr. Cemil Tascıoglu City Hospital
name: yavuz atar, Asso Prof,MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Firat Ozer F, Akin S, Soysal T, Gokcekuyu BM, Erturk Zararsiz G. Relationship Between Dysphagia and Sarcopenia with Comprehensive Geriatric Evaluation. Dysphagia. 2021 Feb;36(1):140-146. doi: 10.1007/s00455-020-10120-3. Epub 2020 Apr 27.
citation: Kara M, Kaymak B, Frontera W, Ata AM, Ricci V, Ekiz T, Chang KV, Han DS, Michail X, Quittan M, Lim JY, Bean JF, Franchignoni F, Ozcakar L. Diagnosing sarcopenia: Functional perspectives and a new algorithm from the ISarcoPRM. J Rehabil Med. 2021 Jun 21;53(6):jrm00209. doi: 10.2340/16501977-2851.
citation: Chen YC, Chen PY, Wang YC, Wang TG, Han DS. Decreased swallowing function in the sarcopenic elderly without clinical dysphagia: a cross-sectional study. BMC Geriatr. 2020 Oct 21;20(1):419. doi: 10.1186/s12877-020-01832-0.