Clinical trial NCT02043496: Integrative Cognitive-Affective Therapy for Binge Eating Disorder
Official title: Integrative Cognitive-Affective Therapy for Binge Eating Disorder
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Binge Eating Disorder
Keywords: Binge Eating Disorder
Binge Eating
Eating Disorders
Obesity
Psychotherapy
Cognitive Behavioral Therapy
Lead sponsor: University of Minnesota
Sponsor class: OTHER
Collaborators: name: Neuropsychiatric Research Institute, Fargo, North Dakota
First posted: 2014-01-23
Enrollment: 96
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The purpose of the study is to test a newly developed individual psychotherapy treatment for binge eating disorder in adults. This treatment is a type of individual psychotherapy called Integrative Cognitive-Affective Therapy (ICAT) that focuses on helping people change their behaviors, feelings, thoughts about themselves, and relationships. This new treatment is being compared to an existing treatment called Cognitive-Behavior Therapy-Guided Self Help (CBTgsh), which focuses on changing behavior patterns through the use of reading and homework assignments along with sessions with a therapist. The primary hypothesis of this investigation is that ICAT will be associated with greater reductions in binge eating at end of treatment and follow-up compared to CBTgsh.


Eligibility criteria: Inclusion Criteria:

* Binge eating disorder (DSM-5)

Exclusion Criteria:

* History of gastric bypass surgery
* Medical condition acutely affecting eating and/or weight
* Current medical and/or psychiatric instability (e.g., acute suicidality)
* Psychosis and/or bipolar disorder
* Severe cognitive impairment or developmental disability
* Inability to read English
* Current substance use disorder
* Current participation in psychotherapy and/or commercial weight loss program
* Change in dosage and/or frequency of psychotropic medication in the past 6 weeks
* Pregnant or breast feeding
* BMI \< 21

Primary outcomes:
measure: Binge Eating Episode Frequency (Eating Disorder Examination)
timeFrame: 17 Weeks and 6-month Follow-up
Secondary outcomes:
measure: Global Eating Disorder Symptoms (EDE)
timeFrame: 17 Weeks and 6-month follow-up
measure: Symptoms of Depression (BDI)
timeFrame: 17 Weeks and 6-month follow-up
measure: Symptoms of Anxiety (STAI)
timeFrame: 17 Weeks and 6-month Follow-up
measure: Self-Esteem (RSEQ)
timeFrame: 17 Weeks and 6-month Follow-up
Other outcomes:
Locations:
city: Minneapolis
country: United States
facility: University of Minnesota
state: Minnesota
city: Fargo
country: United States
facility: Neuropsychiatric Research Institute
state: North Dakota
Study officials:
affiliation: University of Minnesota
name: Carol B Peterson, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Neuropsychiatric Research Institute/University of North Dakota
name: Stephen A Wonderlich, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Peterson CB, Engel SG, Crosby RD, Strauman T, Smith TL, Klein M, Crow SJ, Mitchell JE, Erickson A, Cao L, Bjorlie K, Wonderlich SA. Comparing integrative cognitive-affective therapy and guided self-help cognitive-behavioral therapy to treat binge-eating disorder using standard and naturalistic momentary outcome measures: A randomized controlled trial. Int J Eat Disord. 2020 Sep;53(9):1418-1427. doi: 10.1002/eat.23324. Epub 2020 Jun 25.