Clinical trial NCT00699985: Psychological Symptoms in Patients With Behcet's Disease by SCL90-R
Official title: Comparison of Psychological Symptoms in Patients With Behcet's Disease and Control Patients by Symptom Check List 90-Revised (SCL-90-R)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Behcet's Syndrome
Keywords: Psychological Symptoms
Behcet's Disease
Lead sponsor: Tehran University of Medical Sciences
Sponsor class: OTHER
First posted: 2008-06-18
Enrollment: 400
Sex: ALL
Minimum age (years): 14
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: BD and Non-BD patients who attended the clinic for their routine follow-up.

Brief summary: To find the overall psychological profile of patients with Behcet's Disease (BD) and compare it with Non-BD patients.patients were checked for psychological symptoms by Symptom Check List 90 Revised (SCL90-R)

Detailed description: 200 BD and 200 Non-BD patients were checked for psychological symptoms by Symptom Check List 90 Revised (SCL90-R). BD diagnosis was based on the new International Criteria for Behcet's Disease (ICBD). Non-BD patients were patients mimicking BD. All patients were asked to complete the SCL90-R when they attended the clinic for their routine follow-up. The demographic information and disease manifestations including ocular and neurological involvement were registered. For those with visual impairment, SCL90-R was applied by an interviewer. Frequencies and descriptive analysis were measured in both BD and Non-BD groups. Means and standard deviations (SD) of visual acuity were calculated. Data collected from SCL90-R did not have normal distribution in any dimension. The mean values of raw numbers, global severity index (GSI), the positive symptoms total (PST) and the positive symptom distress index (PSDI), were compared by Mann-Whitney U (M-W U) test.).To detect any bias in results due to data collection method, self reported data and reviewer collected data were compared.

Eligibility criteria: Inclusion Criteria:

* Behcet's disease patients that their diagnosis was based on the new International Criteria for Behcet's Disease (ICBD).
* Non-Behcet's disease patients were patients mimicking BD.

Exclusion Criteria:

* Probable Behcet's Disease

Primary outcomes:
Secondary outcomes:
measure: Total score of SCL90-R dimensions and global indexes
timeFrame: 22months
Other outcomes:
Locations:
city: Tehran
country: Iran, Islamic Republic of
facility: Rheumatology Research Center, Shariati Hospital
Study officials:
affiliation: Rheumatology Research Center, Tehran University for Medical Sciences
name: Bahar Sadeghi, MD
role: STUDY_DIRECTOR
affiliation: Rheumatology Research Center, Tehran University for Medical Sciences
name: Fereydoun Davatchi, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Memory and Behavioral Department, Roozbeh Hospital, Tehran University for Medical Sciences
name: Maryam Noroozian, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Rheumatology Research Center, Tehran University for Medical Sciences
name: Farhad Shahram, MD
role: PRINCIPAL_INVESTIGATOR
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