Clinical trial NCT04047329: Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate
Official title: Risk Factors and Impact of Anesthesia Techniques on Myocardial Infarction Following Transurethral Resection of the Prostate: a Nationwide Database Case Control Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Anesthesia
Transurethral Resection of Prostate Syndrome
Myocardial Infarction
Lead sponsor: Chang Gung Memorial Hospital
Sponsor class: OTHER
First posted: 2019-08-06
Enrollment: 115025
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients receiving TURP

Brief summary: This study examined the risk factors and the influence of the type of anesthetic used during transurethral resection of the prostate (TURP) on subsequent incidence of myocardial infarction (MI).

Detailed description: This study utilized a population-based, nationwide dataset to evaluate the risk factors of MI for patients with benign prostate hypertrophy (BPH) who received TURP. Besides, The study also compared the different effects of general anesthesia (GA) and neuraxial anesthesia (NA) on the incidence of MI within 6 and 12 months after TURP.

Eligibility criteria: Inclusion Criteria:

* Patients receiving TURP surgery (1998-2012)

Exclusion Criteria:

* Patients without anesthesia records
* Patients receiving both general and neuraxial anesthesia
* Mortality within 12 months of TURP

Primary outcomes:
measure: Postoperative myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Postoperative myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Patient's age (year-old) that developed post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Patient's age (year-old) that developed post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed Diabetes Mellitus developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed disorders of lipoid metabolism developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed gout developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed hypertension developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed heart disease history developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed stroke history developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed liver cirrhosis history developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed chronic obstructive pulmonary disease developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarction
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients with pre-operative diagnosed asthma developing post-TURP myocardial infarction
timeFrame: within 12 months after the first admission for TURP
Secondary outcomes:
measure: Number of patients who had post-operative myocardial infarction after receiving general anesthesia for TURP
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients who had post-operative myocardial infarction after receiving neuraxial anesthesia for TURP
timeFrame: within 6 months after the first admission for TURP
measure: Number of patients who did not have post-operative myocardial infarction after receiving general anesthesia for TURP
timeFrame: within 12 months after the first admission for TURP
measure: Number of patients who did not have post-operative myocardial infarction after receiving neuraxial anesthesia for TURP
timeFrame: within 12 months after the first admission for TURP
Other outcomes:
Locations:
Study officials:
References: