Clinical trial NCT01732315: Adolescent Vaccination Reminder Study
Official title: Adolescent Vaccination Reminders Using Email
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Adolescent Vaccination Status
Keywords: Adolescent vaccination
Immunization rates
Barriers to vaccination
Attitudes
Intentions
Lead sponsor: University of Colorado, Denver
Sponsor class: OTHER
Collaborators: name: University of Michigan
name: Centers for Disease Control and Prevention
First posted: 2012-11-22
Enrollment: 3783
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This protocol describes a study about vaccination uptake among adolescents. The purpose of the study is to determine whether parents who receive email reminders will be more likely to obtain Tdap (tetanus-diphtheria-acellular pertussis), HPV (human papilloma virus), meningococcal, and influenza vaccines for their adolescent children than parents who do not receive email reminders.

Detailed description: Adolescents are a reservoir population for a variety of vaccine preventable diseases (VPDs). Despite this, adolescent vaccination rates lag substantially behind national goals of 80% coverage for adolescent vaccines set forth by Healthy People 2020. This has been particularly the case for the vaccines most recently recommended for adolescents, such as the HPV (human papilloma virus) and seasonal influenza (flu) vaccines; national coverage levels in 2010 for HPV were 32% (for series completion among females only) and 35% for flu vaccine. Uptake levels for the two other adolescent-targeted vaccines, Tdap and meningococcal conjugate (MCV4) vaccines are currently at 69% and 63%, respectively.

A major barrier to increased adolescent vaccination levels is the lack of parental and provider recognition that an adolescent is due for vaccine doses. For providers, there are the dual challenges of getting adolescents to come in for annual preventive care visits and also minimizing "missed opportunities" for vaccination (i.e. clinical interactions with a patient where a needed vaccine could have been provided but was not). Reminder/recall systems are one mechanism to help address both of these challenges for providers while also informing parents about the need for adolescent vaccines.

Eligibility criteria: Inclusion Criteria:

* Parents of adolescents (Ages 11-18) have children who attend one of 4 participating pediatric practices,
* Parents are able to read and converse in English,
* Parents have an active email address that is associated with their child's medical record,
* Parents have an adolescent whose medical record can be matched with their MCIR record.

Exclusion Criteria:

* Parent age \<18 years,
* Parents have an invalid or non-working parent email address,
* Parents have opted out of email communication,
* Prisoners,
* Decisionally challenged participants.

Primary outcomes:
measure: New immunization doses
timeFrame: New immunizations within 60 days of reminder notification
Secondary outcomes:
measure: Waived immunization doses
timeFrame: Waived immunizations within 60 days of reminder notification
measure: Historical immunization doses
timeFrame: Historical immunizations within 60 days of reminder notification
Other outcomes:
Locations:
city: Ann Arbor
country: United States
facility: University of Michigan
state: Michigan
Study officials:
affiliation: University of Michigan
name: Kevin Dombkowski, DrPH
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Colorado, Denver
name: Amanda Dempsey, MD, PhD, MPH
role: PRINCIPAL_INVESTIGATOR
References:
citation: Dombkowski KJ, Cowan AE, Reeves SL, Foley MR, Dempsey AF. The impacts of email reminder/recall on adolescent influenza vaccination. Vaccine. 2017 May 25;35(23):3089-3095. doi: 10.1016/j.vaccine.2017.04.033. Epub 2017 Apr 25.