Clinical trial NCT06611865: Comparison of Intraligamentary Anesthesia With the Inferior Alveolar Nerve Block for the Extraction of Mandibular Molars.
Official title: Cross-sectional Study Documenting the Relative Efficacy of Intraligamentary Anesthesia and the Inferior Alveolar Nerve Block for the Extraction of Posterior Mandibular Teeth.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Tooth Extraction
Tooth Extraction Site Healing
Keywords: Intraligamentary Anaesthesia
Inferior Alveolar Nerve Block
Tooth Extraction
Dry Socket
Lead sponsor: Nishtar Medical University
Sponsor class: OTHER
First posted: 2024-09-25
Enrollment: 535
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: A split-mouth group was included with 70 teeth extracted from 35 patients. In such cases, involving bilaterally indicated teeth, ILA and IANB were used on opposite sides, but the second tooth was anesthetized only after the first extraction had completed and had been recorded. The second group had 500 patients with unilateral extractions. ILA was compared with IANB in each group separately, and the results in group I were then compared descriptively with those in group II.
Primary purpose: SUPPORTIVE_CARE

Brief summary: Local anaesthesia or numbing is done before tooth extraction. This study compares two different methods of numbing molar teeth before extraction. It compares them on the basis of pain during the procedure and on discomfort after the procedure as well. It will help dentists better understand the benefits of the two techniques, and their usage case to case.

Detailed description: The study was designed as a randomized controlled trial. The purpose of this study was to examine the differences in efficacy of the intraligamentary anaesthetic technique and the inferior alveolar nerve block for mandibular posterior tooth extraction cases. Pain intensity, duration of anaesthesia, incidence of post-operative dry socket, success rates, onset of anaesthesia were examined. It was done in a split-mouth method so that two different techniques were used in the same patient, thus minimizing individual variations.

Eligibility criteria: Inclusion Criteria:

* Patients of both sexes who were more than 18 years of age; they had indications of non-surgical extraction of one or multiple mandibular posterior teeth.

Exclusion Criteria:

* For patients: pregnancy, immunological compromise, systemic conditions requiring special considerations and non-compliance.
* The exclusion criteria for individual teeth were: acutely infected teeth or any teeth with the instances of expression of pus through sinus tracts or the gingival sulcus were excluded. In case of multiple unilaterally indicated teeth that were to be extracted under IANB, only the tooth best fitting all criteria was considered for the study.

Primary outcomes:
measure: Injection pain
timeFrame: Through the duration of injection (within a few seconds to 1 minute)
measure: Pain during extraction procedure
timeFrame: For the duration of treatment (estimated within 1 hour)
measure: Unpleasantness of treatment
timeFrame: For the duration of treatment (estimated within 1 hour)
measure: Latency time of anesthesia (minutes)
timeFrame: Anesthesia was tested with a dental probe on the marginal gingiva at: 1) immediately after the injection and 2) every 10 seconds (ILA) / every 30 seconds (IANB) until complete painlessness was achieved.
measure: Anesthetic effect
timeFrame: For the duration of treatment (estimated within 2 hours)
measure: Amount of anesthetic solution (mL)
timeFrame: For the duration of treatment (estimated within 1 hour)
measure: Duration of treatment (minutes)
timeFrame: For the duration of treatment (estimated up to 1 to 2 hours)
measure: Duration of local numbness (minutes)
timeFrame: For the duration of treatment (estimated up to 1 to 2 hours)
Secondary outcomes:
measure: Incidence of Dry socket
timeFrame: From the complete extraction of tooth to 14 days after the extraction of tooth
Other outcomes:
Locations:
city: Multan
country: Pakistan
facility: Nishtar Institute of Dentistry
state: Punjab
Study officials:
affiliation: Nishtar Institute of Dentistry
name: Amjad Bari, MDS
role: STUDY_CHAIR
References: