Clinical trial NCT03074578: Is There a Desensitization During Sleep After Exposure to a Violent Verbal Input ?
Official title: Y a T-il Une désensibilisation Pendant le Sommeil après la réception de Violence Verbale ?
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Verbal Abuse
Keywords: sleep
verbal abuse
polysomnography
perception
neuropsychological tests
Lead sponsor: Centre National de la Recherche Scientifique, France
Sponsor class: OTHER
Collaborators: name: Institut National de la Santé Et de la Recherche Médicale, France
First posted: 2017-03-09
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Watching two different videos (one violent, one non-violent), re-exposure after 11h daytime (wake period) or 11h nighttime (sleep period). The order of videos is balanced, in a cross over fashion
Primary purpose: OTHER

Brief summary: There is a need for quantify the emotional and neurophysiological perception of verbal violence, in order to understand the impact it might have on a subject. This project aims at assessing the influence of time, sleep, and people interaction on the perception of verbal violence.

Detailed description: There are many processes involved in the perception of verbal violence. There is a need for quantified data to have a better understanding the physiological and neurological perception of verbal violence, in order to understand the impact it might have on a subject. This project aims at assessing the influence of time, sleep, and people interaction on the perception of verbal violence. The "cognitive replay" will also be assessed through dreams. The investigators think that sleep plays a role in desensitization to negative emotions and to memory consolidation. However, the role of sleep in verbal violence remains unknown.

Eligibility criteria: Inclusion Criteria:

* Subject fully understands French
* Subject willing to consent to the study and signed the written consent
* Subject is afiliated to the Freanch national health care system (Sécurité Sociale)
* Subject level of education superior to "Brevet des collèges" (an equivalent would be the general certificate of secondary education)

Exclusion Criteria:

* The subject is not able to understand the protocol
* The subject has a language disorder
* The subject has a psychiatric or neurological disorders
* The subject does not use psychotropic drugs
* The subject has watched the advertidement : "stop djihadisme", broadcasted on television by the french government

Primary outcomes:
measure: Heart rate
timeFrame: During each video exposure (duration 1.2 min), 4 times
Secondary outcomes:
measure: Sweating
timeFrame: During the video exposure (duration 1.2 min), 4 times
measure: Vasoconstriction
timeFrame: During the video exposure (duration 1.2 min), 4 times
measure: Emotions
timeFrame: Just after the video exposure, during 1 min
Other outcomes:
Locations:
city: Paris
country: France
facility: Service des pathologies du sommeil, Hôpital Pitié Salpêtrière
Study officials:
affiliation: Pitie Salpêtrière Hospital, Paris, France
name: Isabelle Arnulf, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Barros A, Uguccioni G, Salkin-Goux V, Leu-Semenescu S, Dodet P, Arnulf I. Simple behavioral criteria for the diagnosis of disorders of arousal. J Clin Sleep Med. 2020 Jan 15;16(1):121-128. doi: 10.5664/jcsm.8136. Epub 2019 Dec 4.