Clinical trial NCT05259293: Characteristics of Pneumothorax Associated With Transthoracic Percutaneous Lung Biopsy in Standard of Care
Official title: Characteristics of Pneumothorax Associated With Transthoracic Percutaneous Lung Biopsy in Standard of Care: a Retrospective Study in 6 Centers
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pneumothorax Iatrogenic Postprocedural
Keywords: interventional radiology, iatrogenic pneumothorax, transthoracic lung biopsy, pneumothorax rate, pneumothorax characteristics, patient management
Lead sponsor: Centre Hospitalier Universitaire de Besancon
Sponsor class: OTHER
Collaborators: name: Institut National de la Santé Et de la Recherche Médicale, France
First posted: 2022-02-28
Enrollment: 243
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult patients who presented with a pneumothorax following their lung biopsy (see eligibility criteria)

Brief summary: The number of lung biopsies has increased steadily in recent years. Pneumothorax is the most common complication of a lung biopsy and can occur during the procedure, immediately after the procedure or within a few hours (delayed pneumothorax). The incidence of pneumothorax in the literature is very different from one study to another: it has been reported to be from 9 to 54% in patients undergoing percutaneous transthoracic needle biopsy. This difference of incidence could be explained by the absence of consensus for the definition of an iatrogenic pneumothorax.

The characteristics of pneumothorax and the management of patients with iatrogenic pneumothorax will be evaluated in different centres in a retrospective manner. This study will contribute to refining the criteria for defining pneumothorax occurring during lung biopsy and will provide a better understanding of the condition and its management.


Eligibility criteria: Inclusion Criteria:

* Patients aged 18 years old and more at the time of the biopsy procedure in year 2020
* Having had a pneumothorax following their transthoracic percutaneous lung biopsy in year 2020

Exclusion Criteria:

* Objection to the use of the data (French sites only)

Primary outcomes:
measure: Annual incidence rate of pneumothorax related to transthoracic lung biopsy on total number of lung biopsies
timeFrame: 3 months
Secondary outcomes:
measure: Annual incidence rate of hospitalisation in patients with pneumothorax related to lung biopsies
timeFrame: 3 months
measure: Annual incidence rate of drainage in patients with pneumothorax related to lung biopsies
timeFrame: 3 months
Other outcomes:
Locations:
city: Besançon
country: France
facility: CHU de Besançon
city: Bordeaux
country: France
facility: Institut Bergonié
city: Tours
country: France
facility: CHU de Tours
city: Villejuif
country: France
facility: Institut Gustave Roussy
city: Dublin
country: Ireland
facility: Saint James Hospital
city: Oxford
country: United Kingdom
facility: Oxford University Hospitals
Study officials:
affiliation: CHU de Besançon
name: Julien BEHR, MD
role: PRINCIPAL_INVESTIGATOR
References: