Clinical trial NCT03868878: Capoeira Training Decrease Plasma Triglycerides
Official title: Twelve Weeks of Capoeira Training Decrease Plasma Triglycerides in Advanced-age Frail Adults of a Long-term Institution
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Physical Conditioning, Human
Lipid Metabolism
Aged
Keywords: Capoeira Training (martial arts)
Triglycerides
Aging
Lead sponsor: Universidade Federal do vale do São Francisco
Sponsor class: OTHER
Collaborators: name: Regional Hospital of Juazeiro, BA, Brazil
name: Research support foundation of the Pernambuco State - FACEPE, Brazil
First posted: 2019-03-11
Enrollment: 14
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Background: Among the risk factors associated with aging, a special highlight has been attributed to cardiovascular dysfunctions, insulin resistance, central obesity and dyslipidemia, which is marked by low levels of cholesterol (high density lipoprotein) and in particular by high levels of plasma triglycerides. Individuals with high levels of plasma triglycerides tend to have a prolonged postprandial hypertriglyceridemia after a fat-meal challenge, which would potentially further increase the risk associated with cardiovascular disease. Due to the impact of aging and its associated risk factors on the older adults health, several strategies have been proposed to avoid the progression of chronic diseases. These diseases are frequent in this population, especially the ones that resides in long-term institutions and they are mainly characterized by sedentary lifestyle and functional inability. Systematic reviews have shown that the implementation of physical activity programs associated with a favorable dietary pattern may benefit the lipid profile of the older adults. Moreover, it is suggested as a primary strategy, the realization of physical exercise as a therapy for this disease. In the physical exercise programs aspects, unconventional modalities such as Capoeira, which is practiced in more than 150 countries, it has aroused interest in the scientific research. Characterized by a system composed by attack and defense movements and from Afro-Brazilian origin, Capoeira combines sports elements of the fight, gymnastics, dance and musicality. However, there is no study investigating the effect of Capoeira training on the lipid profile of older adults, which would have an important clinical application in the health of this population, especially living in conditions of sedentarism and frailty in long-term institutions.

Aim: The present study analyzed the effects of twelve weeks of Capoeira training on the lipid profile of advanced-age frail adults of a long-term institution, which are characterized by sedentary lifestyle and affected by several diseases.

Methods: Participants were assigned into two groups (CONTROL: n = 07; 82.4±13.6 years and CAPOEIRA: n = 07; 79.4±6.9 years). The CAPOEIRA group performed twelve weeks of Capoeira training program, being twice a week lasting 60 minutes each at light to moderate intensity. Samples of 10 ml of blood were collected from participants' antecubital vein at the pre- and post-intervention moments in both groups. Plasma concentrations of triglycerides, total cholesterol, low density lipoprotein cholesterol and high density lipoprotein cholesterol were evaluated using the enzymatic colorimetric method. Anthropometry measures were performed and to internal control the energy consumption evaluations were carried out through daily food diaries during intervention period.


Eligibility criteria: Inclusion Criteria:

* age greater than 60 years;
* is not engaged in physical exercise programs for at least one year;
* do not present severe cardiovascular disease, kidney disease, liver disease or limiting cognitive or neuromuscular disease and;
* does not present visual or auditory inability.

Exclusion Criteria:

* failing to perform any of the evaluations suggested during the intervention protocol and;
* absence in five or more Capoeira training sessions.

Primary outcomes:
measure: Change from baseline triglycerides concentration at 3 months
timeFrame: Pre- (week zero) and Post- (through study completion, 12 weeks) in Capoeira training group and Control group
Secondary outcomes:
Other outcomes:
Locations:
city: Petrolina
country: Brazil
facility: Federal University of Vale do São Francisco (UNIVASF).
state: Pernambuco
Study officials:
affiliation: Federal University of Vale do São Francisco
name: Sérgio R Moreira, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Moreira SR, Teixeira-Araujo AA, Dos Santos AO, Simoes HG. Ten weeks of capoeira progressive training improved cardiovascular parameters in male practitioners. J Sports Med Phys Fitness. 2017 Mar;57(3):289-298. doi: 10.23736/S0022-4707.16.06030-8. Epub 2016 Feb 3.
citation: Moreira SR, Teixeira-Araujo AA, Numata Filho ES, Moraes MR, Simoes HG. Psychophysiological characterization of different capoeira performances in experienced individuals: A randomized controlled trial. PLoS One. 2018 Nov 15;13(11):e0207276. doi: 10.1371/journal.pone.0207276. eCollection 2018.
citation: Moreira SR, Carvalho FO, Moraes JFVN, Carvalho RGS, Araújo RC, Teixeira-Araújo AA, Okano AH. Eight weeks of Capoeira progressive training program increases flexibility of beginners. Sport Sci Health 12: 329-337, 2016.