Clinical trial NCT07018232: Enhancing Timely Access to Medication Changes: The Role of Pharmacists in Overcoming Transitions of Care Challenges
Official title: Enhancing Timely Access to Medication Changes: The Role of Ambulatory Care Pharmacists in Overcoming Transitions of Care Challenges
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Transitional Care
Keywords: pharmacist
medication access
hospital discharge
Lead sponsor: The Guthrie Clinic
Sponsor class: OTHER
First posted: 2025-06-12
Enrollment: 104
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Adult patients discharged from an acute care hospital with a change in their chronic prescription medication regimen

Brief summary: Objective: Among patients discharged from the hospital with changes in maintenance prescription medication, how does experiencing a medication access gap compared to a no medication access gap impact the time to first unplanned healthcare encounter?

This is a retrospective, cohort study conducted at two hospital sites in rural Pennsylvania and New York State using encounter data from the electronic health record to analyze any patient discharged with medication changes from June 1, 2023 to May 31, 2024.

Detailed description: Background: Transitions of care are high-risk periods marked by frequent medication-related problems with up to 80% of discharged patients and 98% of older adults experiencing discrepancies in their medication regimens. These gaps, often due to delayed prescription refills or poor care coordination, contribute to unplanned healthcare encounters, increased costs, and strain on providers. Pharmacists can mitigate these risks by improving medication access and continuity.

Objective: Among patients discharged from the hospital with changes in maintenance prescription medication, how does experiencing a medication access gap compared to a no medication access gap impact the time to first unplanned healthcare encounter?

This is a retrospective, cohort study conducted at two hospital sites in rural Pennsylvania and New York State using encounter data from the electronic health record to analyze any patient discharged with medication changes from June 1, 2023 to May 31, 2024.

Eligibility criteria: Inclusion Criteria:

* Age 18 years and older
* Have a Guthrie primary care provider
* Discharged from the hospital to home or self-care (routine)
* Had a medication change on discharge based on a discharge summary and/or after visit summary (AVS) containing "start taking these medications", "continue these medications which have changed", and/or "stop taking these previous medications".

Exclusion Criteria:

* Age less than 18 years of age
* Do not have a Guthrie primary care provider
* Discharged from the hospital to anywhere besides home or self-care (routine) such as to rehabilitation, long-term care, left against medical advice, or transferred to another type of healthcare institution
* prescriptions on discharge that lack e-prescribing class
* prescriptions on discharge for day supplies less than 28 days
* prescriptions on discharge for day supplies greater than 45 days
* prescriptions on discharge with 1 or more refills provided
* prescriptions on discharge for as needed medications
* prescriptions on discharge for anti-infective agent
* prescriptions on discharge for short-term steroids
* prescriptions on discharge for nausea medication
* prescriptions on discharge for bowel regimen medication
* prescriptions on discharge for diabetic or medical supplies
* prescriptions on discharge for topical medications
* prescriptions on discharge for cough suppressants,
* prescriptions on discharge for vitamins and supplements
* prescriptions on discharge for medications that can be purchased over the counter

Primary outcomes:
measure: Number of days to first unplanned healthcare encounter post-discharge
timeFrame: 90 days after discharge
Secondary outcomes:
measure: Number of days that a patient is without a prescribed medication post-discharge
timeFrame: 90 days after discharge
measure: Describe the types of drug-related problems and/or medication access barriers between the two groups
timeFrame: 90 days after discharge
Other outcomes:
Locations:
city: Sayre
country: United States
facility: Robert Packer Hospital
state: Pennsylvania
Study officials:
affiliation: The Guthrie Clinic
name: Alison Van Dyke, PharmD
role: PRINCIPAL_INVESTIGATOR
References: