Clinical trial NCT05769088: Effects of a Multi-Ingredient Pre-Workout Supplement on Body Composition, Performance, Muscular Properties, and Wellbeing in Adults.
Official title: Effects of a Protein-Based Multi-Ingredient Pre-Workout Supplement on Body Composition, Performance, Perceptual Responses, Energy Feelings and Muscular Properties, in Middle-Aged and Older Adults.
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Protein Deficiency
Training Group, Sensitivity
Fatigue
Muscular Atrophy
Psychological
Keywords: Fatigue
Supplement
Protein
Resistance Training
Pre-workout
Strength
Rate of Perceived Exertion
Muscle
Lead sponsor: University of Greenwich
Sponsor class: OTHER
Collaborators: name: Crown Sport Nutrition
name: Go Fit Spain
First posted: 2023-03-15
Enrollment: 40
Sex: ALL
Minimum age (years): 45
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: 6 Weeks of resistance training (alternate days), with a Pre-workout or Maltodextrin intake.
Primary purpose: TREATMENT

Brief summary: The investigation will be conducted as a double blinded, randomized, parallel between treatment conditions comparison design with two different groups ingesting a different supplement each one.

Detailed description: Following inclusion, familiarization and baseline assessments, the participants will be randomly allocated to receive either a multi-ingredient, pre-workout supplement (PREW) or maltodextrin (CHO). Thereafter, the participants will follow a 6-weeks resistance training mesocycle, involving three resistance training sessions (Monday, Wednesday and Friday) per week (18 sessions in total). Before and after the 6 weeks of intervention, the following assessments will be performed: (i) Body composition (fat mass and fat-free mass) via air displacement plethysmography (BodPod); (ii) muscle contractile properties on Vastus Medialis and Anterior Deltoids (via Tensiomyography; (iii) muscle structure of the Vastus Lateralis of the Quadriceps and the Elbow Flexors of dominant extremities via Ultrasound; (iv) Maximal Isometric Strength (Isometric Mid-Thigh Pull); (v) Upper and Lower Body Muscular Power (Medicine Ball Throw and Vertical Jump), (vi) Upper and Lower Muscular Endurance (30-Seconds Sit-to-Stand and 30-Seconds 16RM Bench Press), (vii) Immune System (via HemoCue WBC DIFF System).

The supplements will be ingested 15 min before each training session.

Energy Feeling Questionnaire will be filled immediately before warming up.

In addition, Rate of Perceived Exertion to training will be assessed 15 min after the completion of all workouts.

Eligibility criteria: Inclusion Criteria:

* Healthy (no injuries, illnesses or medication intake).
* Between 45 and 65 years old.
* Active and familiarised with Resistance Training.

Exclusion Criteria:

* Unhealthy (illnesses or medication intake) or injured.
* Untrained.
* Young (\<45 y.o.) or elderly (\>65 y.o.).

Primary outcomes:
measure: Tensiomyography
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
measure: Vertical Jump
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
measure: Chest Medicine Ball Throw
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
measure: Maximal Mid-Thigh Pull Isometric Strength
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
measure: Muscle Thickness
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
measure: Self Perceived Energy Feeling
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
measure: Whole Body Perceptual Response during Resistance Training
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
Secondary outcomes:
measure: White Blood Cells count
timeFrame: Changes from 3 days previous to, and 3 days after the completion of the 6-weeks training program
Other outcomes:
Locations:
city: London
country: United Kingdom
facility: University of Greenwich, Avery Hill Campus, Sparrows Farm. Avery Hill, London., United Kingdom, SE9 2BT
state: Avery Hill, London.
Study officials:
References: