Clinical trial NCT02752217: Effectiveness of Inspiratory Muscle Training With Slow Breathing in Elderly With ISH
Official title: Effectiveness of Inspiratory Muscle Training With Antihypertensive Breathing Technique on Lung and Exercise Capacity in Elderly With Isolated Systolic Hypertension
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Hypertension
Lead sponsor: Khon Kaen University
Sponsor class: OTHER
First posted: 2016-04-26
Enrollment: 32
Sex: ALL
Minimum age (years): 60
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Study the effects of inspiratory muscle training at Low load of 25 %Maximal inspiratory pressure with slow breathing rate at 6 breaths/min on inspiratory muscle strength, lung function, chest wall expansion, abdominal expansion, exercise capacity and blood pressure in elderly with Isolated systolic hypertension.

Detailed description: Study the effects of inspiratory muscle training at Low load of 25 % Maximal inspiratory pressure with slow breathing rate at 6 breaths/min with BreatheMAXยฎdevice for 8 weeks at home on inspiratory muscle strength, lung function (slow vital capacity, inspiratory capacity), chest wall expansion, abdominal expansion, exercise capacity by arm ergometry and blood pressure in elderly with Isolated systolic hypertension. who have age 60-80 years.

Eligibility criteria: Inclusion Criteria:

1. Subjects aged 60 to 80 years of age with an essential isolated systolic hypertension stage I II based on recommendation of JNC VII from primary care units in community and the Outpatient Department of Srinakarind hospital in Khon Kaen province Thailand
2. Good communication and co operation
3. Independent physical activity
4. Stable controlled hypertension

Exclusion Criteria:

1. Essential isolated systolic hypertension stage III or secondary hypertension
2. History of heart disease such as coronary artery disease myocardial infarction
3. History of respiratory disease such as asthma chronic bronchitis
4. History of neuromuscular disease such as muscle weakness cerebrovascular disease
5. History of renal disease
6. Exercise limited by pain

Primary outcomes:
measure: Change from baseline in Maximal inspiratory pressure (MIP)
timeFrame: Baseline and at 8 weeks
Secondary outcomes:
measure: Lung capacity
timeFrame: Baseline and at 8 weeks
measure: Exercise capacity
timeFrame: Baseline and at 8 weeks
measure: Chest wall expansion and abdominal expansion
timeFrame: Baseline and at 8 weeks
measure: Blood pressure (BP)
timeFrame: Baseline and at 8 weeks
Other outcomes:
Locations:
city: Na Muang
country: Thailand
facility: Faculty of Associated Medical Sciences
state: Khon Kaen
Study officials:
affiliation: Faculty of Associated Medical Sciences.
name: Phailin Tongdee, Master
role: PRINCIPAL_INVESTIGATOR
References:
citation: Jones CU, Sangthong B, Pachirat O. An inspiratory load enhances the antihypertensive effects of home-based training with slow deep breathing: a randomised trial. J Physiother. 2010;56(3):179-86. doi: 10.1016/s1836-9553(10)70023-0.
citation: Ublosakka-Jones C, Tongdee P, Pachirat O, Jones DA. Slow loaded breathing training improves blood pressure, lung capacity and arm exercise endurance for older people with treated and stable isolated systolic hypertension. Exp Gerontol. 2018 Jul 15;108:48-53. doi: 10.1016/j.exger.2018.03.023. Epub 2018 Mar 28.