Clinical trial NCT04941352: Motivational Interviewing in Patients With Schizophrenia
Official title: The Effect of Interpersonal Relations Theory-Based Motivational Interviews on Functional Recovery and Insight Levels of Patients With Schizophrenia
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Motivational Interviews
Schizophrenia
Keywords: Insight
Functional Recovery
Interpersonal Relations Theory
Motivational Interviews
Schizophrenia
Lead sponsor: Pamukkale University
Sponsor class: OTHER
First posted: 2021-06-28
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized controlled pre-post test design
Primary purpose: SUPPORTIVE_CARE

Brief summary: Introduction: A poor therapeutic relationship, low insight and lack of motivation are associated with poor adjustment (to symptoms, treatment, and environment) in patients with schizophrenia. In order to achieve better compliance and results, the therapeutic relationship and insight should be developed by increasing the motivation of individuals.

Purpose: This study examines the effect of Interpersonal Relations Theory-Based motivational interviews on functional recovery and insight levels of patients with schizophrenia.

Methods: This single-blind, randomized controlled study used the simple randomization method and employed a pretest-posttest control group design, which is an experimental research design. The study was conducted at Pamukkale University, Health Research and Application Center, Habib Kızıltaş Psychiatric Hospital from November 2019 to June 2020 and included 40 individuals (20 in the experimental and 20 in the control groups). Study data were collected using a personal information form, the Functional Remission of General Schizophrenia Scale (FROGS) and the Scale for Assessing the Three Components of Insight (SAI). The researchers carried out a 6-session Interpersonal Relations Theory-based motivational interview with the participants in the experimental group. No intervention was made to the control group. The data were analyzed on the basis of pre-intervention, post-intervention and 3 months after the intervention (follow-up).

Detailed description: Schizophrenia is a severe mental illness that causes problems in the thoughts, feelings, and behaviors of the individual, impairs the ability to evaluate reality, has a unique world and keeps the individual away from social life, causes difficulties in his family and social environment, relapses, and is a progressive, severe mental illness when regular treatment is not applied.

It is reported that individuals diagnosed with schizophrenia have poor insight into how they evaluate the symptoms of the disease and what they expect from treatment. One of the problems of individuals diagnosed with schizophrenia is lack of motivation. It is stated that this may be caused by the dopaminergic system. This situation can cause individuals to have difficulties in social life.

In this context, it is important to evaluate motivational processes in the treatment of schizophrenia and to plan and implement initiatives that will increase motivation. A poor therapeutic relationship, low insight and lack of motivation are associated with poor adjustment (to symptoms, treatment, and environment) in patients with schizophrenia. In order to achieve better compliance and results, the therapeutic relationship and insight should be developed by increasing the motivation of individuals. Nurses need to establish a therapeutic relationship in order for the nursing care to produce effective results in the recovery process of these patients.

In this study, it is thought that Interpersonal Relations-Based Motivational Interviewing can be effective in increasing the symptom management, social-occupational functionality, adherence to treatment, daily life skills and insight levels of patients with schizophrenia, and may shed light and guide psychiatric nursing interventions.

Eligibility criteria: Inclusion Criteria:

* To be at least primary school graduate,
* Living in the city center of Denizli,
* Being open to communication and cooperation.
* Being between the ages of 18-65,
* Being in remission (period without psychotic exacerbation),
* To have a diagnosis of schizophrenia according to DSM-5 (The Diagnostic and Statistical Manual of Mental Disorders) diagnostic criteria.

Exclusion Criteria:

* Being under the age of 18 and over the age of 65,
* Being illiterate in Turkish,
* Having Mental Retardation,
* Being diagnosed with a mental illness other than schizophrenia according to the DSM-5 diagnostic criteria,
* Being in a psychotic attack period.

Primary outcomes:
measure: Assessing the Three Components of Insight Score
timeFrame: Change from baseline Assessing the Three Components of Insight score at 3 months
measure: Functional Remission of General Schizophrenia Score
timeFrame: Change from baseline Functional Remission of General Schizophrenia score at 3 months
Secondary outcomes:
measure: Number of health care uses
timeFrame: Change in the number of initial health care use in the 3rd month
Other outcomes:
Locations:
city: Denizli
country: Turkey
facility: Pamukkale University Pamukkale University, Faculty of Health Science, Departmant of Psychiatric Nursing
state: Kınıklı Kampus
Study officials:
affiliation: Pamukkale University
name: Gülay Yiğitoğlu, PhD
role: STUDY_DIRECTOR
affiliation: Pamukkale University
name: Nesrin Çunkuş, Msc
role: PRINCIPAL_INVESTIGATOR
affiliation: Pamukkale University
name: Ayşe Nur İnci Kenar, PhD
role: STUDY_CHAIR
References:
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citation: World Health Organisation (WHO) 2019. Schizophrenia. [Last accessed on 2021 May 6]. Available from: https://www.who.int/news-room/fact-sheets/detail/schizophrenia
citation: Cho JM, Lee K. Effects of motivation interviewing using a group art therapy program on negative symptoms of schizophrenia. Arch Psychiatr Nurs. 2018 Dec;32(6):878-884. doi: 10.1016/j.apnu.2018.07.002. Epub 2018 Jul 19.
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citation: Ertem MY, Duman ZC. The effect of motivational interviews on treatment adherence and insight levels of patients with schizophrenia: A randomized controlled study. Perspect Psychiatr Care. 2019 Jan;55(1):75-86. doi: 10.1111/ppc.12301. Epub 2018 Jun 11.