Clinical trial NCT01994811: Eastern Caribbean Health Outcomes Research Network (ECHORN)
Official title: Eastern Caribbean Health Outcomes Research Network (ECHORN)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cancer
Cardiovascular Disease
Diabetes
Keywords: cancer
cardiovascular disease
diabetes
Lead sponsor: Yale University
Sponsor class: OTHER
Collaborators: name: National Institute on Minority Health and Health Disparities (NIMHD)
First posted: 2013-11-26
Enrollment: 2961
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The population-based prospective cohort is comprised of adults aged 40 and older living in four countries: Puerto Rico (PR), Barbados (BB), the US Virgin Islands (USVI), and Trinidad and Tobago (TT).

Brief summary: The Eastern Caribbean Health Outcomes Research Network (ECHORN) is a collaborative research study that examines the lifestyles, eating habits, and health behaviors associated with cancer, diabetes and heart disease in adult men and women living in the Eastern Caribbean.

Detailed description: The Eastern Caribbean Health Outcomes Research Network (ECHORN) has two aims: (1) To form a research collaborative across the Eastern Caribbean islands of Puerto Rico, the U.S. Virgin Islands, Barbados, and Trinidad \& Tobago to recruit and follow a community-dwelling adult cohort to estimate the prevalence of known and potential risk factors associated with the development of heart disease, cancer, and diabetes and (2) To enhance health outcomes research leadership capacity in the region through a series of dedicated activities locally and abroad. ECHORN will expand clinical research with racial/ethnic minority populations in a transitioning part of the globe now threatened with an epidemic of noncommunicable chronic diseases (NCD). ECHORN's findings will have direct implications for the health disparities research and policy agenda in the mainland United States. In the long term, the links ECHORN will facilitate with local health policy delegations and global strategic organizational partners will promote the translation of research to improve health outcomes across the region. The collection and storage of biological specimens will also contribute to national biomonitoring projects and has the potential to identify unique risk and protective factors in the development of NCD.

Eligibility criteria: Inclusion Criteria:

* Greater than or equal to 40 years of age
* English or Spanish language speaking
* Resident of island at least 10 years
* Able to provide informed consent
* Non-institutionalized at the time of data collection
* Stable contact/residential information
* No plans to relocate from island within the next 5 years

Primary outcomes:
measure: Prevalence of non-communicable diseases
timeFrame: 5 years
Secondary outcomes:
Other outcomes:
Locations:
city: Bridgetown
country: Barbados
facility: University of the West Indies, Cave Hill Campus
city: San Juan
country: Puerto Rico
facility: University of Puerto Rico Medical Sciences Campus
city: St. Augustine
country: Trinidad and Tobago
facility: University of the West Indies, St. Augustine Campus
state: West Indies
city: Charlotte Amalie
country: Virgin Islands (U.S.)
facility: University of the Virgin Islands
Study officials:
affiliation: Yale University
name: Marcella Nunez-Smith, MD, MHS
role: PRINCIPAL_INVESTIGATOR
References: