Clinical trial NCT05482750: Resistance Training in the Fasted State
Official title: Effects of Resistance Training Performed in the Fasted State Compared to the Fed State on Morphological and Neuromuscular Adaptations in Young Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Fasting
Exercise
Resistance Training
Lead sponsor: Federal University of Rio Grande do Sul
Sponsor class: OTHER
First posted: 2022-08-01
Enrollment: 28
Sex: ALL
Minimum age (years): 19
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: It is well evidenced in the literature that fasting aerobic exercise generates a series of metabolic differences when compared to exercise performed in the fed state, including the use of fats predominantly as an energy source. Consequently, increases in adaptations to aerobic training, related to health and physical performance, are observed when sessions are performed in the fasted state. In relation to resistance training, the evidence is limited. There is a lack of data in the literature regarding the effects of fasting on resistance exercises and whether this practice may reflect in losses or improvements in morphological and neuromuscular adaptations related to resistance training. Thus, the aim of the present project is to compare the effects of resistance training performed in the fasted state compared to the fed state during 12 weeks on body composition and physical performance in young adults. Thirty-four eutrophic or overweight individuals, not engaged in regular resistance exercises, aged between 20 and 40 years, will be recruited. They will be put on a standard customized diet and will perform 2 weekly sessions of resistance exercise after overnight fasting (10 to 12 hours) or in the fed state, for 12 weeks. Before, in the middle and after this period, evaluations of body composition, muscle thickness and quality, maximum dynamic strength and maximum power will be analyzed. Comparisons will be performed using Generalized Estimating Equations (GEE), adopting the factors group (2 stratifications) and time (3 stratifications). All results will be expressed as mean and standard deviation and the accepted significance level will be 5%.


Eligibility criteria: Inclusion Criteria:

* Men and women;
* Aged between 19 and 40 years;
* Body mass index (BMI) between 18 and 29.9 kg/m²;
* Not engaged in regular strength physical exercise (\>1 weekly session) for the last 3 months.

Exclusion Criteria:

* Smokers;
* Use of medications and/or supplements that may influence the outcomes evaluated;
* Individuals who have a chronic disease that may prevent physical exercise.

Primary outcomes:
measure: Body mass
timeFrame: 1 minute
measure: Lean body mass
timeFrame: 15 minutes
measure: Fat body mass
timeFrame: 15 minutes
measure: Muscle thickness
timeFrame: 30 minutes
measure: Muscle quality
timeFrame: 30 minutes
measure: Maximum dynamic strength
timeFrame: 30 minutes
measure: Maximum power
timeFrame: 30 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Porto Alegre
country: Brazil
facility: Escola de Educação Física, Fisioterapia e Dança - UFRGS
state: Rio Grande Do Sul
Study officials:
References: