Clinical trial NCT06776107: Mortality in Brain Injury at the Intensive Care Unit (TraVi II)
Official title: Factors Associated With Mortality in Brain Injury at the Intensive Care Unit. A Cross-sectional Trial, 2019-2023 (TraVi II)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Traumatic Brain Injuries
Keywords: Brain Injuries
Traumatic Brain Injuries
Brain Concussion
Traffic Accidents
Critical Care
Colombia
Lead sponsor: Hospital Departamental de Villavicencio
Sponsor class: OTHER
First posted: 2025-01-15
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population was patients with traumatic brain injury who were admitted to the intensive care unit.

Brief summary: Introduction: traumatic brain injuries are a leading cause of disability and mortality in the young population, associated mainly with traffic road accidents and violent wounds. The study aimed to analyze factors related to the mortality in patients with brain injury admitted to the intensive care unit.

Methodology: Between 2019 and 2024, an analytical cross-sectional trial at Hospital Departamental de Villavicencio, Colombia was performed. Information was selected from the intensive care unit (ICU) database. Variables of interest and outcomes, such as mortality and ICU length of stay, were identified. The comparison was performed with the software Prism® for Mac iOS and Wizard® for the predictive model.

Results: The study will show the factors associated with mortality of brain injury patients admitted to the intensive care unit.

Detailed description: Objective: The study aimed to analyze factors related to the mortality in patients with brain injury admitted to the intensive care unit.

Methodology: Between 2019 and 2024, an analytical cross-sectional trial at Hospital Departamental de Villavicencio, Colombia, a reference center for the Colombian Orinoco region with 400 hospital beds and 53 polyvalent ICU beds was performed. Information was selected from 2,154 admission registers in the intensive care unit (ICU) database. Data of admissions considered for review were from patients with diagnostic codes of brain injury, brain edema, polytrauma, ventilatory failure, neurogenic shock, and traumatic subarachnoid hemorrhage. All the registries with codes S00-S09 from the 10th revision of the International Diseases Classification from the World Health Organization were reviewed. Variables of interest and outcomes, such as mortality and ICU length of stay, were identified. The comparison was performed with the software Prism® for Mac iOS and Wizard® for the predictive model.

Results: The study will show the factors associated with mortality of brain injury patients admitted to the intensive care unit.

Eligibility criteria: Inclusion Criteria:

* Traumatic brain injury.
* Admitted to the intensive care unit.

Exclusion Criteria:

* Remission from another hospital.
* Decease for causes other than the brain injury.

Primary outcomes:
measure: ICU mortality
timeFrame: 30 days
Secondary outcomes:
measure: ICU length of stay
timeFrame: 30 days
Other outcomes:
Locations:
city: Villavicencio
country: Colombia
facility: Hospital Departamental de Villavicencio
state: Meta
Study officials:
affiliation: Hospital Departamental de Villavicencio
name: Norton Perez, MD
role: PRINCIPAL_INVESTIGATOR
References:
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