Clinical trial NCT00687089: Examination of Cognitive Function in Patients Treated With Subutex
Official title: Examination of Cognitive Function, Weight, Sexual Function in Patients Receiving Treatment With Subutex at 3 Months Without Using Opiates
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Opiate Addiction
Keywords: Opiates
Subutex
Buprenorphine
Patients who addicted to opiates
Lead sponsor: BeerYaakov Mental Health Center
Sponsor class: OTHER_GOV
Collaborators: name: Ebetim Clinic
First posted: 2008-05-30
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: People who suffer from addiction problems (opiates) and willing to start Buprenorphine treatment

Brief summary: People who addicted to Heroin and other opiates suffer from a disease with approved genetic basis. It causes to a behavioral response as searching and using those drugs even though they know it causes severe damages as physiological, familiar and legal affairs.

The popular treatment's goal is to "clean" the people from any drug. In a medical and pharmacological point of view there is no sense in this approach for all people. This point of view believes that Buprenorphine (Subutex) is a correct pharmacological treatment.

The hypothesis of this research is that people using Buprenorphine have difficulties in gaining weight, in sexual and cognitive function (according to subjects' reports)

Detailed description: People who addicted to Heroin and other opiates suffer from a disease with approved genetic basis. It causes to a behavioral response as searching and using those drugs even though they know it causes severe damages as physiological, familiar and legal affairs.

The popular treatment's goal is to "clean" the people from any drug. In a medical and pharmacological point of view there is no sense in this approach for all people. This point of view believes that Buprenorphine (Subutex) is a correct pharmacological treatment.

The hypothesis of this research is that people using Buprenorphine have difficulties in gaining weight, in sexual and cognitive function (according to subjects' reports) We examine people who stopped opiates and began Buprenorphine. Every participant in the study will have two visits: the first one before receiving Buprenorphine and the second one after 3 months of receiving Buprenorphine.

Eligibility criteria: Inclusion Criteria:

* People who suffer from addiction problems (opiates)
* People who willing to to start Buprenorphine treatment
* People who willing to cooperate with study tests and questionnaires
* People aged 18 to 70

Exclusion Criteria:

* People who suffer from any neurocognitive problems
* People who suffer from mental illnesses
* People who are having legal guardian

Primary outcomes:
measure: ASI quationarry, neurocognitive computerized tests, MMSE test, Sexual function questionnaire and satisfaction questionnaire
timeFrame: In 2 visits during the study
Secondary outcomes:
Other outcomes:
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Study officials:
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