Clinical trial NCT07002307: The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Some Physiological Parameters
Official title: The Effect of Honey-sweetened Coffee, Black Tea and Green Tea on Blood Pressure, Heart Rate and Blood Glucose
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Blood Pressure
Heart Rate
Blood Glucose
Keywords: Coffee
Honey-sweetened coffee
Black tea
Honey-sweetened black tea
Green Tea
Honey-sweetened green tea
Blood pressure
Heart rate
Blood glucose
Lead sponsor: University of Uyo Teaching Hospital
Sponsor class: OTHER
First posted: 2025-06-03
Enrollment: 70
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 26
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: The goal of this clinical trial is to investigate whether a three-day consumption of honey-sweetened black tea, green tea, and coffee will have an effect on blood pressure, heart rate, and blood glucose. The main questions it aims to answer are:

Does honey-sweetened black tea, green tea, and coffee, respectively, have the ability to influence blood pressure, heart rate, or blood glucose level?

Research will compare honey-sweetened black tea, green tea, and coffee to a placebo (warm water) to see if honey-sweetened black tea, green tea, and coffee work to reduce or increase blood pressure, heart rate, or blood glucose.

Participants will:

Take honey-sweetened black tea, green tea, and coffee, OR plain black tea, green tea, and coffee, OR warm water, one cup a day for 3 days The beverages will be taken at the Physiology laboratory, University of Uyo, and the participants will be observed for 60 minutes, during which their blood pressure, heart rate, and blood glucose level will be measured. This procedure will be repeated for the 3 days of study.


Eligibility criteria: Inclusion Criteria:

Inclusion criteria are as follows:

* Age between 18 and 26
* Non-habitual coffee and tea drinkers who consume coffee, green tea, or black tea 2-5 times in the last two months
* Non-allergic to coffee, green tea, black tea, or honey
* Absence of medication use
* Will refrain from ingesting energy drinks, carbonated beverages, caffeinated beverages, or food for 24 hours before the study and throughout the study periods
* Will not consume anything except water after 11 p.m. during the experimental days Will be available and cooperate throughout the study duration.

Exclusion Criteria:

Exclusion criteria are as follows:

* Presence of cardiovascular disorders, hypertension, or diabetes
* Blood pressure above 120/80 mmHg and random blood glucose above 125 mg/dL
* Alcohol intake
* Smoking
* Habitual coffee or tea drinker

Primary outcomes:
measure: Blood pressure
timeFrame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
measure: Heart rate
timeFrame: Will be measured before consumption of the beverages and at 15, 30, 45, and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
measure: Blood glucose
timeFrame: Will be measured before consumption of the beverages and at 30 and 60 minutes after consumption of the beverages. This procedure will be repeated for 3 consecutive days.
Secondary outcomes:
measure: Age
timeFrame: Will obtained during the eligibility process
measure: Height
timeFrame: Will be measured on the first day of the experiment before the commencement of the experiment.
measure: Body weight
timeFrame: Measurements will be taken over the course of the 3-day study prior to the commencement of the experiment each day.
Other outcomes:
Locations:
city: Uyo
country: Nigeria
facility: Physiology laboratory, Physiology Department, Faculty of Basic Medical Sciences, University of Uyo
state: Akwa-Ibom
Study officials:
affiliation: University of Uyo
name: Esther O Aluko
role: PRINCIPAL_INVESTIGATOR
References: