Clinical trial NCT05656456: Impact of COVID-19 on Mental Health of OCD Patients and live-in Family Members
Official title: The Impact of the COVID-19 Pandemic on Patients With Obsessive-Compulsive Disorder and Their live-in Family Members
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Obsessive-Compulsive Disorder
Keywords: Family accommodation
Covid-19
Lead sponsor: University Hospital, Ghent
Sponsor class: OTHER
First posted: 2022-12-19
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: OCD patients followed at the Centre of OCD and their live-in family members

Brief summary: The impact of the current Covid-19 pandemic on mental health of people with preexisting psychiatric problems is enormous. This longitudinal study investigates the prevalence of mental health problems (obsessive compulsive, or depressive symptoms, anxiety, stress...) of obsessive-compulsive disorder (OCD) patients and their live-in family members. We also aim to investigate the impact of the pandemic, isolation measures, exposure to media and changing therapeutic setting in OCD patients and their live-in family members through qualitative research.

Detailed description: The impact of the current Covid-19 pandemic on mental health of people with preexisting psychiatric problems is enormous. Previous studies during the SARS outbreak demonstrated a significant burden and increase of mental health problems in people with preexisting psychiatric problems, but little is known about the impact on preexisting obsessive-compulsive disorder (OCD). This longitudinal study aims to investigate the prevalence of mental health problems of OCD patients during and after the Covid-19 pandemic. We also want to investigate the impact on family accommodation (FA). There is growing evidence that FA maintains and/or facilitates OCD symptoms. OCD patients and their live-in family members, followed at the Centre for OCD of the Ghent university hospital, will be included. Sociodemographic data, data regarding employment and previous mental health problems will be collected at the first survey. The Y-BOCS (OCD symtoms) and FAS (family accommodation) will be taken from patients and family members respectively at the start, after 1, 3 and 6 months. The Depression, Anxiety and Stress Scale (DASS-21), the Dutch translation of the Covid-19 Peritraumatic Distress Index (CPDI) will be administered at the same time points through an online survey.

Secondly, patients and live-in family members will be interviewed about their experiences concerning the covid pandemic, the isolation measures, media exposure and change of mental health practice and the impact on the OCD (qualitative research).

Eligibility criteria: Inclusion Criteria:

* OCD patients
* live-in family members of OCD patients

Exclusion Criteria:

* not speaking fluently Dutch

Primary outcomes:
measure: OCD symptoms in patients at baseline
timeFrame: Baseline
measure: Family accommodation in family members at baseline
timeFrame: Baseline
measure: Change in OCD symptoms in patients
timeFrame: Baseline + 30 days, baseline + 90 days, baseline + 180 days
measure: Change in family accommodation in family members
timeFrame: Baseline + 30 days, baseline + 90 days, baseline + 180 days
Secondary outcomes:
measure: Depressive symptoms at baseline in patients and family members
timeFrame: Baseline
measure: Change in depressive symptoms in patients and family members
timeFrame: Baseline + 30 days, baseline + 90 days, baseline + 180 days
measure: Anxiety symptoms at baseline in patients and family members
timeFrame: Baseline
measure: Change in anxiety symptoms in patients and family members
timeFrame: Baseline + 30 days, baseline + 90 days, baseline + 180 days
measure: Stress levels at baseline in patients and family members
timeFrame: Baseline
measure: Change in stress levels in patients and family members
timeFrame: Baseline + 30 days, baseline + 90 days, baseline + 180 days
measure: Covid-19 related psychological stress at baseline in patients and family members
timeFrame: Baseline
measure: Change in Covid-19 related psychological stress in patients and family members
timeFrame: Baseline + 30 days, baseline + 90 days, baseline + 180 days
Other outcomes:
Locations:
city: Ghent
country: Belgium
facility: Ghent University Hospital
Study officials:
affiliation: University Hospital, Ghent
name: Gilbert MD Lemmens, MD, PhD
role: STUDY_DIRECTOR
References: