Clinical trial NCT06510244: Pain Perception Measurement by EEG and NRS
Official title: Measuring Pain Perception to the Same Stimulus in Different Patients Using Electroencephalography and Numerical Rate Scale
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Pain
Electroencephalography
Toothache
Keywords: pain perception
Numeric Pain Rating Scale
electroencephalography
Lead sponsor: Cleveland Dental Institute
Sponsor class: OTHER
First posted: 2024-07-19
Enrollment: 100
Sex: ALL
Minimum age (years): 20
Maximum age (years): 60
Standard ages: ADULT
Observational model: OTHER
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: In the outpatient clinic of CDI Cleveland Dental Institute, patients with mature and vital tooth #8 are between 20 and 60 years old.

Brief summary: Observational study at CDI Cleveland Dental Institute. Investigators will assess the pain perception in one group of patients using two non-invasive methods. First, a numerical rate scale (NRS) and second, a brain wave EEG.

Detailed description: To generate the nociceptive stimulus, The investigators will apply cold (Endo-Ice) to a healthy upper incisor tooth #8. Inclusion criteria: Patients between 20 and 60 years old, with healthy teeth, no history of dental alveolar trauma, and no pulp chamber calcification. After the nociceptive stimulus, patients will write their pain perception on paper from 0 to 10, and at the same time, we will record the brain activity with a non-invasive EEG Emotiv. Then, we will correlate both methods.

Eligibility criteria: Inclusion Criteria:

* Males and females
* Age: 20-60 years.
* Tooth #8 vital and mature. No history of dentoalveolar trauma.
* Adequate coronal tooth structure.

Exclusion Criteria:

* Chronic periodontitis.
* Vertical root fracture.
* Immature teeth.
* Necrotic teeth.
* Systemic diseases that affect the healing process.
* Non restorable teeth.

Primary outcomes:
measure: Pain Perception Measurement by EEG.
timeFrame: January 2024-December 2024
measure: Pain Perception Measurement by EEG and NRS.
timeFrame: January 2024-December 2024
Secondary outcomes:
Other outcomes:
Locations:
city: Cleveland
country: United States
facility: Cleveland Dental Institute
state: Ohio
Study officials:
References:
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citation: Holsheimer J, Feenstra BW. Volume conduction and EEG measurements within the brain: a quantitative approach to the influence of electrical spread on the linear relationship of activity measured at different locations. Electroencephalogr Clin Neurophysiol. 1977 Jul;43(1):52-8. doi: 10.1016/0013-4694(77)90194-8.