Clinical trial NCT03306056: Whole-body Electromyostimulation Versus Conventional Low-volume Strength Training in Overweight Individuals
Official title: Comparison of the Effects of Whole-body Electromyostimulation Versus Conventional Low-volume Strength Training in Overweight Individuals at Increased Cardiometabolic Risk
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Overweight and Obesity
Metabolic Syndrome
Keywords: Exercise
Strength Training
Health Promotion
Inflammation
Body Composition
Lead sponsor: University of Erlangen-Nürnberg Medical School
Sponsor class: OTHER
First posted: 2017-10-10
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: parallel-group, randomized-controlled study
Primary purpose: TREATMENT

Brief summary: The main purpose of this study is to compare the effects of whole-body electromyostimulation versus a conventional low-volume strength-training program, each combined with an individualized, weight-reducing diet, on the cardiometabolic risk profile, muscle strength, body composition, inflammatory markers and subjective health outcomes in overweight individuals at increased cardiometabolic risk.


Eligibility criteria: Inclusion Criteria:

* Body Mass Index \>25
* presence of at least 2 cardiometabolic risk factors

Exclusion Criteria:

* Healthy persons or patients under age
* Overweight persons without any additional cardiometabolic risk factors
* Pregnancy, Lactation
* Psychological disorders, epilepsy, sever neurological disorders
* Participation in other exercise- or nutrition studies within the last 6 months
* acute cardiovascular disease
* malignant disease
* Rheuma
* Intake of anabolic drugs,
* Skin injuries in the area of electrode placements
* Electronic implants (defibrillator, pacemaker)
* Persons in mental hospitals by order of authorities or jurisdiction

Primary outcomes:
measure: Metabolic Syndrome Z-Score (MetS-Z-Score)
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
Secondary outcomes:
measure: Muscle strength
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Body Composition
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Cardiorespiratory Fitness (CRF)
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Inflammation status
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Health-related quality of life
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Pain scores
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Perceived stress
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
measure: Subjective work ability
timeFrame: 12 weeks (baseline to 12 week follow-up assessment)
Other outcomes:
Locations:
city: Erlangen
country: Germany
facility: Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports,
Study officials:
affiliation: University Erlangen Nuremberg Medical School
name: Dejan Reljic, Dr.
role: PRINCIPAL_INVESTIGATOR
affiliation: University Erlangen Nuremberg Medical School
name: Yurdaguel Zopf, Prof.
role: PRINCIPAL_INVESTIGATOR
References: