Clinical trial NCT05615207: The Effect of Motor Imagery on Balance in Persons With Multiple Sclerosis
Official title: The Effect of Motor Imagery on Balance in Persons With Multiple Sclerosis
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Falls
Motor Imagery
Multiple Sclerosis
Balance
Fatigue
Lead sponsor: Dominican University New York
Sponsor class: OTHER
First posted: 2022-11-14
Enrollment: 10
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized Controlled Trial - participants will be randomized into the Standard of Care (physical practice) or the Motor Imagery group. Blocked randomization will be implemented to ensure even comparison between groups . Then each person will receive one on one training based on the item(s) on the BBS with which they had difficulty.
Primary purpose: TREATMENT

Brief summary: This study will investigate if the use of motor imagery to practice a balance task is as effective as physically practicing balance tasks as measured by the Berg Balance Scale (BBS) in persons with MS. A secondary purpose is to investigate if using a motor imagery balance intervention will limit fatigue typically experienced with physical movement in this population.

Detailed description: Motor Imagery, where persons practice mental performance of a task without the physical performance of the task has been found to improve many aspects of mobility in persons with MS. Its effect on balance is not known. Traditionally, balance training in persons with MS(pwms) has taken the form of physical performance of balance tasks. Although this is effective, this may increase the fatigue that commonly limits physical exercise in MS.

The purpose of this study is to compare the effects of Motor Imagery on physical performance on balance and fatigue in persons with MS.

Upon a participant's arrival to Dominican University NY, we will:

A) Provide participants with an informed consent, explain the process, and answer questions B) Collect intake data (demographics and subject characteristics - age, gender, ethnicity, EDSS/ Phenotypes, years since diagnosis, MS Impact Scale-29 (MSIS29), Fatigue Severity Scale (FSS), Activities-Specific Balance Confidence scale (ABC) C) Collect baseline observational measures: Berg Balance Scale (BBS)

The participants will then be randomized into the Standard of Care (physical practice) or the Motor Imagery group. Blocked randomization will be implemented to ensure even comparison between groups. Then each person will receive one on one training based on the item(s) on the BBS with which they had difficulty. For example, if the participant had difficulty with item 13 on the BBS, practicing that item would become part of their intervention. Participants in the Standard of Care group will be instructed on how to physically practice their items. Participants in the Motor Imagery group will be guided through mentally practicing their items.

The interventionist will select the 3 items on the BBS with which the participant struggled the most and provide in person and HEP instructions based on those items. We will instruct the participant to perform 10 minutes of total daily practice of these exercises at home in the mode indicated by their group. The 10 minutes will be divided among multiple exercises if applicable and can be done either all at once or broken up over the course of the day. Participants will receive a logbook with written and/or verbally recorded instructions on how to perform their exercises.

Participants will perform the interventions at home for 10 minutes a day for 2 weeks, and will then return to DUNY after the 2 weeks for post-test data collection.

Eligibility criteria: Inclusion Criteria:

* Confirmed diagnosis of Multiple Sclerosis
* A non-perfect score on the Berg Balance Scale

Exclusion Criteria:

* A perfect score on the Berg Balance Scale
* Current participation in a program focused on improving balance

Primary outcomes:
measure: Berg Balance Test
timeFrame: Two weeks
Secondary outcomes:
measure: MS Impact Scale-29 (MSIS29)
timeFrame: Two weeks
measure: Fatigue Severity Scale (FSS)
timeFrame: Two weeks
measure: Activities-Specific Balance Confidence scale (ABC)
timeFrame: Two weeks
Other outcomes:
Locations:
city: Orangeburg
country: United States
facility: Dominican University New York
state: New York
Study officials:
affiliation: Dominican University New York
name: Stefanie DiCarrado, DPT
role: PRINCIPAL_INVESTIGATOR
References: