Clinical trial NCT00967980: Femoral Versus Psoas Continuous Peripheral Nerve Blocks Following Hip Arthroplasty
Official title: Femoral Versus Psoas Continuous Peripheral Nerve Blocks Following Hip Arthroplasty
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Hip Arthroplasty
Hip Pain
Keywords: pain
Hip Resurfacing
catheter
nerve block
UCSD
hip surgery
psoas
femoral
ambulation
hip flexion
infusion
Lead sponsor: University of California, San Diego
Sponsor class: OTHER
First posted: 2009-08-28
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this research study is to determine if the insertion site of a perineural catheter, or tiny tube placed next to the nerves that go to the hip which you will have surgery, affects the amount of pain relief that is experienced after surgery.

Detailed description: To determine the association between perineural catheter location and postoperative analgesia, analgesic requirements, ambulatory distance, and flexion following hip arthroplasty.

Primary Hypothesis: Differing the catheter insertion site (femoral vs. psoas compartment) for a perineural local anesthetic infusion is not associated with lower pain scores during the 24-hour period beginning the morning following hip arthroplasty.

Eligibility criteria: Inclusion Criteria:

* primary, unilateral hip arthroplasty or hip resurfacing
* age greater than or equal to 18 years
* postoperative analgesic plan includes perineural local anesthetic infusion

Exclusion Criteria:

* morbid obesity (BMI greater than 40)
* chronic, high-dose opioid use
* history of opioid abuse
* pregnancy
* incarceration
* amu meirp-muscular deficit of the ipsilateral femoral nerve and/or quadriceps muscle
* inability to communicate with hospital staff

Primary outcomes:
measure: Patient's mean pain score (NRS) during perineural infusion as measured by the nursing staff at UCSD and entered in the computer system.
timeFrame: 24 hours beginning 7:30am day following surgery
Secondary outcomes:
measure: Analgesic used, as reported by nursing staff in the UCSD computer system.
timeFrame: 3 days following surgery
measure: Patient's ambulation distance as recorded by therapist (occupational or physical) in the UCSD computer system.
timeFrame: 3 days following surgery
measure: Hip flexion, in degrees measured with a standard goneometer, as recorded by therapist (occupational or physical) in the UCSD computer system.
timeFrame: 3 days following surgery
measure: Infusion duration of pain pump, measured on the pump itself in hours and minutes.
timeFrame: 3 days following surgery
measure: Duration of hospital stay, in hours, as reported in the UCSD computer system.
timeFrame: 3 days following surgery
measure: Surgical/anesthetic adverse events as reported by hospital staff
timeFrame: day of surgery and 3 days following
measure: Experiences of patient during the infusion and following, as reported to study staff in a phone conversation, one week following surgery.
timeFrame: 1 week following surgery
Other outcomes:
Locations:
city: San Diego
country: United States
facility: UCSD Medical Center
state: California
Study officials:
affiliation: University of California, San Diego
name: Brian M Ilfeld, M.D., M.S.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Ilfeld BM, Mariano ER, Madison SJ, Loland VJ, Sandhu NS, Suresh PJ, Bishop ML, Kim TE, Donohue MC, Kulidjian AA, Ball ST. Continuous femoral versus posterior lumbar plexus nerve blocks for analgesia after hip arthroplasty: a randomized, controlled study. Anesth Analg. 2011 Oct;113(4):897-903. doi: 10.1213/ANE.0b013e318212495b. Epub 2011 Apr 5.