Clinical trial NCT05727488: SARAH Exercise Program in Patients With Rheumatoid Arthritis
Official title: Investigating the Effects of SARAH Exercise Program on Proprioception and Hand Functions in Patients With Rheumatoid Arthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Rheumatoid Arthritis
Keywords: Hand
Proprioception
Exercise
Lead sponsor: Izmir Katip Celebi University
Sponsor class: OTHER
First posted: 2023-02-14
Enrollment: 49
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The aim of this study is to investigate the effectiveness of the SARAH home exercise program to be applied for 12 weeks on wrist proprioception and hand functions in adult patients with rheumatoid arthritis.

Detailed description: Finger/hand/wrist joints can be affected in the early period in patients with RA, and as the disease progresses, it can significantly limit the patient's functionality. Damage to articular and periarticular structures seen in inflammatory arthritis may affect the sense of proprioception by destroying mechanoreceptors located in these areas. Hand functions may worsen as a result of the worsening of the sense of proprioception, which can be defined as being aware of body parts.

SARAH (Strengthening and Stretching for Rheumatoid Arthritis of the Hand) home exercise program, which is a widely preferred approach in the case of hand involvement in patients with rheumatoid arthritis (RA), includes exercises to increase hand-wrist strength and mobility. Although the effectiveness of this program on pain, muscle strength, and range of motion has been demonstrated in large patient groups, its effect on proprioception and hand functions, which may be caused by inflammatory arthritis, has not been studied. Therefore, this study aims to investigate the effectiveness of the SARAH home exercise program on wrist proprioception and hand functions in adult patients with rheumatoid arthritis.

Eligibility criteria: Inclusion Criteria:

1. RA diagnosis according to 2010 ACR/EULAR RA criteria
2. Being between the ages of 18-65
3. Being able to follow Turkish instructions
4. Volunteering to participate in the study

Exclusion Criteria:

1. Being in an acute disease exacerbation period
2. Ongoing physiotherapy/occupational/exercise treatment regarding hands within the last 6 months
3. History of steroid injection, surgery, or trauma to the upper extremity in the last 6 months

Primary outcomes:
measure: Change in Wrist Joint Position Sense
timeFrame: At baseline and twelve weeks later
measure: Change in Hand Performance
timeFrame: At baseline and twelve weeks later
measure: Change in Grip Strength
timeFrame: At baseline and twelve weeks later
measure: Change in Pinch Strength
timeFrame: At baseline and twelve weeks later
measure: Change in Self-reported Hand Functions
timeFrame: At baseline and twelve weeks later
Secondary outcomes:
measure: Change in Pain
timeFrame: At baseline and twelve weeks later
measure: Change in Morning Stiffness
timeFrame: At baseline and twelve weeks later
measure: Change in Disease Activity
timeFrame: At baseline and twelve weeks later
measure: Change in General Functioning
timeFrame: At baseline and twelve weeks later
Other outcomes:
Locations:
city: İzmir
country: Turkey
facility: Izmir Katip Celebi University
Study officials:
affiliation: Izmir Katip Celebi University
name: Deniz Bayraktar, PT, PhD
role: PRINCIPAL_INVESTIGATOR
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