Clinical trial NCT03627078: Motor Interference Therapy For Traumatic Memories
Official title: The Effect of Motor Interference Therapy In Traumatic Memories: A Controlled Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Trauma, Psychological
Post Traumatic Stress Disorder
Keywords: traumatic memories
post traumatic stress disorder
motor interference therapy
non pharmacological therapy
trauma related disorders
Lead sponsor: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Sponsor class: OTHER
First posted: 2018-08-13
Enrollment: 28
Sex: ALL
Minimum age (years): 16
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study is to compare the effect of motor interference therapy (TIM) to reduce the intensity of discomfort (distress) generated by a traumatic memory compared to a relaxation control maneuver, immediately after the intervention, a week, a month and six months after intervention.

Detailed description: The investigators treated 10 patients with autobiographical traumatic memories using finger tapping tasks, (Motor Interference Therapy \<TIM\>)in a pilot study with amazing results and a solid size effect. The investigators decided to challenge the intervention using a control task (Jacobson´s progressive relaxation exercises) The hypothesis consists in achieving a 30% reduction of the distress, (measured with Visual Analogue Scale) by using TIM compared with the control task. Patients with traumatic memories will be enrolled in to one of two treatment modalities. The first group will receIve motor interference therapy and the second group will receive a control task (relaxation exercises). Both groups will be assessed using the Spanish version of the PTSD Symptom Severity Scale-Revised (EGS-R), the visual analogue scale (EQ-VAS) from EuroQol 5D (EQ-5D), and a simple visual-analogue scale (VAS) immediately after, a week after, a month after and six months after the treatment for follow up.

Eligibility criteria: Inclusion Criteria:

* Patients older than 16 years
* Spanish as a native language
* Give written informed consent
* having at least 1 traumatic memory causing distress

Exclusion Criteria:

* Neurological or psychiatric disorders that affect the capacity of verbal comprehension and judgment, such as dementia, psychosis, mental retardation or other cognitive alteration that does not allow them to perform the tasks indicated in the TIM or SHAM
* History of recent substance abuse
* Patients with significant hearing loss or some other hearing impairment

Primary outcomes:
measure: Change in Visual Analogue Scale (EVA)
timeFrame: baseline, immediately, 1 week, 1 month, 6 months
Secondary outcomes:
measure: Spanish version of the PTSD Symptom Severity Scale-Revised (EGS-R)
timeFrame: baseline, 1 week, 1 month, 6 months
measure: visual analogue scale (EQ-VAS) from EuroQol 5D (EQ-5D)
timeFrame: baseline, 1 week, 1 month, 6 months
Other outcomes:
Locations:
city: Mexico
country: Mexico
facility: Instituto Nacional de Neurologia Y Neurocirugia Mvs
state: Ciudad De Mexico
Study officials:
affiliation: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
name: Edgar D Crail-Melendez, MD
role: PRINCIPAL_INVESTIGATOR
References: