Clinical trial NCT05498246: Bipolar Coagulation Versus Suture Renorrhaphy in Laparoscopic Partial Nephrectomy
Official title: Bipolar Coagulation Versus Suture Renorrhaphy for Hemostasis of Tumour Bed in Laparoscopic Partial Nephrectomy: Prospective Randomized Comparative Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Nephrectomy
Lead sponsor: Benha University
Sponsor class: OTHER
First posted: 2022-08-12
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Patients were divided into two groups by close envelope method in this prospective study. group (A) included 30 cases in which we used bipolar coagulation for hemostasis ,group (B) included 30 cases in which we used suture renorrhaphy.
Primary purpose: TREATMENT

Brief summary: To compare between bipolar coagulation of tumor bed in laparoscopic partial nephrectomy versus suture renorrhaphy

Detailed description: Partial nephrectomy is the standard of care for T1 renal masses (local tumour) it preserves as much normal renal tissue as possible to avoid post-operative acute renal failure, chronic kidney disease and associated metabolic and cardiovascular morbidities . The main challenges that affect partial nephrectomy outcome is the need for renal ischemia to achieve good hemostasis, and the long-term oncological consequences associated with positive surgical margin. Laparoscopic partial nephrectomy has been widely used lately as it is associated with less blood loss, short hospital stay and early recovery in comparison to open partial nephrectomy . Hemostasis of the tumor bed after laparoscopic partial nephrectomy can be achieved by various techniques including Suture renorrhaphy which can be used whatever the bleeding area, the size of bleeding vessel, or the amount of bleeding. However, it consumes more ischemia time, involves functional parenchyma, and requires high laparoscopic skills . There for in our study we tried to find a way to improve the functional and oncological outcome of laparoscopic partial nephrectomy by comparing the bipolar coagulation versus conventional suture renorrhaphy in performing stable hemostasis of tumor bed

Eligibility criteria: Inclusion Criteria:

* Radiological diagnosis of renal mass less than 7cm
* Renal mass in patients with chronic kidney disease

Exclusion Criteria:

* Patients with Central or hilar renal masses
* Renal masses close to pelvi-calyceal system

Primary outcomes:
measure: To compare between bipolar coagulation of tumor bed in laparoscopic partial nephrectomy versus suture renorrhaphy
timeFrame: baseline frame
Secondary outcomes:
Other outcomes:
Locations:
city: Banhā
country: Egypt
facility: Mohamed Kadry Mostafa
state: Qalubia
Study officials:
affiliation: Data analysis
name: mostafa khalil, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: data collections
name: Ali Abdelkarim, MD
role: PRINCIPAL_INVESTIGATOR
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