Clinical trial NCT01820988: MaSS - Maastricht Sarcopenia Study
Official title: Cross-sectional Study on the Identification and Characterization of Community-dwelling Older People With Sarcopenia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Sarcopenia
Lead sponsor: Maastricht University Medical Center
Sponsor class: OTHER
Collaborators: name: Nutricia Research Fundation
First posted: 2013-03-29
Enrollment: 247
Sex: ALL
Minimum age (years): 65
Maximum age (years): 99
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Community-dwelling older people

Brief summary: The objective of this cross-sectional study is to obtain insight in the characteristics (nutritional status and level of physical activity) of sarcopenic compared to non-sarcopenic community-dwelling older people. There is one measurement moment and measurements will take place at the participant's home.

Detailed description: * Characterization of sarcopenic older people (demographics, nutritional status, level of physical activity)
* Prevalence rates of sarcopenia in community-dwelling older people in the Netherlands
* Insight in differences and/or overlap between sarcopenia versus frailty
* Insight in the impact of sarcopenia on economic outcomes

Eligibility criteria: Inclusion Criteria:

* ≥ 65 years old
* Have given informed consent
* Understand Dutch language
* Able to perform a walk test

Exclusion Criteria:

* Older people living in a nursing home
* Older people with active rheumatoid arthritis, post stroke status with evident lingering symptoms (paralysis, loss of motor functions), diseases of the nervous system like Parkinson and MS, active angina pectoris, dementia
* Older people in a wheelchair, with ICD or pacemaker

Primary outcomes:
measure: Mean difference in nutritional status and level of physical activity of sarcopenic participants vs. non-sarcopenic participants, as a measure of a Food Frequency Questionnaire and Mini-Nutritional Assessment Tool and Minnesota questionnaire
timeFrame: 1 home visit
Secondary outcomes:
measure: Prevalence of sarcopenia in community-dwelling older people
timeFrame: 1 home visit
measure: Number of sarcopenic participants with frailty as a measure of the FRAIL scale and Fried criteria
timeFrame: 1 home visit
measure: Health care costs by sarcopenic vs. non-sarcopenic participants, measured by health care use
timeFrame: 1 home visit
Other outcomes:
Locations:
city: Maastricht
country: Netherlands
facility: Maastricht University
Study officials:
affiliation: Maastricht University
name: J.M.G.A. Schols, Prof. Dr.
role: STUDY_DIRECTOR
affiliation: Maastricht University
name: R.J.G. Halfens, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Maastricht University
name: J.M.M. Meijers, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Maastricht University
name: D.M. Mijnarends, MSc
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mijnarends DM, Meijers JM, Halfens RJ, ter Borg S, Luiking YC, Verlaan S, Schoberer D, Cruz Jentoft AJ, van Loon LJ, Schols JM. Validity and reliability of tools to measure muscle mass, strength, and physical performance in community-dwelling older people: a systematic review. J Am Med Dir Assoc. 2013 Mar;14(3):170-8. doi: 10.1016/j.jamda.2012.10.009. Epub 2012 Dec 29.
citation: Mijnarends DM, Schols JM, Meijers JM, Tan FE, Verlaan S, Luiking YC, Morley JE, Halfens RJ. Instruments to assess sarcopenia and physical frailty in older people living in a community (care) setting: similarities and discrepancies. J Am Med Dir Assoc. 2015 Apr;16(4):301-8. doi: 10.1016/j.jamda.2014.11.011. Epub 2014 Dec 17.