Clinical trial NCT04986878: Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty
Official title: Comparison Between the Analgesic Effects of Single Shot Versus Continuous Adductor Canal Block in Patients Undergoing Total Knee Arthroplasty
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Rheumatism Knee
Lead sponsor: Aswan University Hospital
Sponsor class: OTHER
First posted: 2021-08-03
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The target population of this study will be patients undergoing primary total knee arthroplasty at Aswan l and Assiut university hospitals
Primary purpose: TREATMENT

Brief summary: Adductor canal block (ACB) has emerged as an option for postoperative regional analgesia in patients undergoing total knee arthroplasty (TKA).

Detailed description: Various approaches to the performance of peripheral nerve blocks for postoperative pain control in patients undergoing TKA have been described in the literature. These approaches include lumbar plexus block, femoral nerve block (FNB), with or without a sciatic nerve block, and most recently the ACB. FNB is a commonly used modality for postoperative analgesia after TKA. It is considered by some as the gold standard or the cornerstone of postoperative analgesia after TKA. However, FNB reduces quadriceps muscle strength essential for mobilization and active contribution in any physical rehabilitation program. Quadriceps weakness places the patients at risk of falling. which may be detrimental to postoperative recovery. The ACB has recently emerged as an appealing alternative to FNB as it is predominately a sensory nerve block of a more distal branch of the femoral nerve ( the saphenous nerve).

Eligibility criteria: Inclusion Criteria:

* Patients scheduled for primary total knee arthroplasty with
* American Society of Anesthesiologists (ASA) physical status I -III,
* mentally competent and able to give consent for enrollment in the study.

Exclusion Criteria:

1. Patient younger than 18 years old or older than 70 years old
2. Allergy to local anesthetics, systemic opioids (fentanyl, morphine, hydromorphone, and any of the drugs included in the multimodal perioperative pain protocol.
3. Revision surgeries were excluded.
4. Impaired kidney functions and patients with coagulopathy were also excluded.
5. Chronic pain syndromes and patients with chronic opioid use defined as the use of regular daily doses of systemic narcotics for the past 6 months prior to the surgery.
6. BMI of 40 or more
7. Pregnancy (positive urine pregnancy test result in Preop area on the morning of surgery)

Primary outcomes:
measure: postoperative pain scores by visual analogue score
timeFrame: 48 hours
Secondary outcomes:
measure: time to up and go test (minutes)
timeFrame: 48 hours
measure: six-minute walking test
timeFrame: 48 hours
measure: the 30-Second Chair test
timeFrame: 48 hours
Other outcomes:
Locations:
city: Aswan
country: Egypt
facility: Aswan University Hospital
city: Aswan
country: Egypt
facility: Huda Fahmy
Study officials:
References: