Clinical trial NCT06657352: Skin Efficacy Testing of Astrion Products
Official title: Skin Efficacy Testing of Astrion Products
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Skin Pigment
Skin Red
Lead sponsor: Chia Nan University of Pharmacy ＆ Science
Sponsor class: OTHER
First posted: 2024-10-24
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: This project aims to conduct safety and efficacy tests on the skin for the ingestion of Astrion Vitality Capsules, containing A. membranaceus and C. Asiatica roots, and the topical application of Astrion Vitality Cream. The goal is to develop health and skincare products that regulate physiological functions, promote overall wellness, and enhance skin beauty.


Eligibility criteria: Inclusion Criteria:

* Subjects aged ≥18 years.

Exclusion Criteria:

* Non-voluntary participants.
* Subjects diagnosed with skin diseases, cirrhosis, or chronic renal failure by a -physician.
* Individuals with known allergies to cosmetics, drugs, or food.
* Pregnant or breastfeeding women.
* Individuals taking medication for chronic diseases.
* Subjects who, within 12 weeks prior to the test, have undergone laser facial treatments, chemical peels, or experienced prolonged sun exposure (more than 3 hours of direct sunlight in a week).
* Students taught by the investigator.
* Individuals unwilling to allow the publication of photos of the experimental results.

Primary outcomes:
measure: skin melanin
timeFrame: The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit
measure: Skin brightness
timeFrame: The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit
measure: skin moisture
timeFrame: The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit
measure: skin elasticity
timeFrame: The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit
measure: collagen density content
timeFrame: The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit
measure: skin surface topography
timeFrame: The topical group applied ACS cream to the face twice daily for 4 weeks. The oral group took one ACS capsule twice daily after meals for 12 weeks. The combination group followed both regimens for 12 weeks. A placebo group, identical in appearance but wit
Secondary outcomes:
Other outcomes:
Locations:
city: Tainan
country: Taiwan
facility: Chia Nan University of Pharmacy ＆ Science
Study officials:
References: