Clinical trial NCT04717778: Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow's Milk in Children
Official title: Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow's Milk in Children
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: pH
Lead sponsor: Universidad Tecnologica de Mexico
Sponsor class: OTHER
First posted: 2021-01-22
Enrollment: 21
Sex: ALL
Minimum age (years): 3
Maximum age (years): 6
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: The study was carried out in 21 first grade primary school children, they were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).
Primary purpose: OTHER

Brief summary: The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female. They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk)

Detailed description: * The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female.
* The group was given a brushing technique using a model and 2 videos were shown to reinforce the brushing technique and explanation of what was going to be done in the study.
* Supervised tooth brushing was performed in a group of 5 people.
* They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).
* Each child was given 7 plastic cups each day and asked to pour their saliva into the cup when instructed.
* The samples were taken with pH indicator strips and the result was recorded in personalized tables.

Eligibility criteria: Inclusion Criteria:

* Boys and girls from 3 to 6 years

Exclusion Criteria

* Boys and girls with allergies
* Children with lactose intolerance

Elimination criteria:

- Boys and girls who do not want to participate at the time of the study

Primary outcomes:
measure: Sociodemographic results
timeFrame: 1 hour the sociodemographic data of all the children were taken.
measure: pH results
timeFrame: The average time of pH evaluation for each milk per child was an hour and a half.
Secondary outcomes:
Other outcomes:
Locations:
city: Mexico City
country: Mexico
facility: UNITEC
Study officials:
affiliation: Universidad Tecnológica Centroamericana
name: Annia Avalos, Master
role: PRINCIPAL_INVESTIGATOR
References:
citation: Vanga SK, Raghavan V. How well do plant based alternatives fare nutritionally compared to cow's milk? J Food Sci Technol. 2018 Jan;55(1):10-20. doi: 10.1007/s13197-017-2915-y. Epub 2017 Nov 2.
citation: Hettinga K, van Valenberg H, de Vries S, Boeren S, van Hooijdonk T, van Arendonk J, Vervoort J. The host defense proteome of human and bovine milk. PLoS One. 2011 Apr 27;6(4):e19433. doi: 10.1371/journal.pone.0019433.
citation: Cuppari C, Manti S, Salpietro A, Dugo G, Gitto E, Arrigo T, Sturiale M, Salpietro C. ALMOND MILK: A POTENTIAL THERAPEUTIC WEAPON AGAINST COW'S MILK PROTEIN ALLERGY. J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2 Suppl 1):8-12.