Clinical trial NCT05573646: Online Group-based Dual-task Training to Improve Cognitive Function of Community-dwelling Older Adults
Official title: Online Group-based Dual-task Training to Improve Cognitive Function of Community-dwelling Older Adults: A Feasibility Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Aging Well
Lead sponsor: The University of Hong Kong
Sponsor class: OTHER
Collaborators: name: Health and Medical Research Fund
First posted: 2022-10-10
Enrollment: 76
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Objectives: This study aims to explore the feasibility, acceptance, and efficacy of online group-based dual-task training as an intervention for improving cognitive function among community-dwelling older adults.

Hypothesis to be tested: We hypothesize that after the intervention, there will be an improvement in the participants' cognitive function as compared with pre-intervention status and with the control group. Also, lower-limb muscle strength and psychosocial wellbeing will be improved after the intervention.

Design and subjects: This is a randomised controlled feasibility study. The target population is community-dwelling older adults with access to an online meeting platform. About 75 participants will be recruited and randomised to the intervention and attention control groups in a ratio of 2:1. Intervention group will receive 60 minutes of online group-based dual-task training twice a week for 12 weeks led by a trained facilitator. Cognitive training components include arithmetic operation, verbal fluency, and upper limb/finger movement. Physical training components are chair-based exercises. The training components will be selected using a co-design approach.

Instruments: Memory Inventory in Chinese (MIC), Digit Span Test, Victoria Stroop Test, Montreal Cognitive Assessment 5-Minutes (Hong Kong Version).

Main outcome measures: Subjective memory complaints as measured by MIC.


Eligibility criteria: Inclusion Criteria:

* aged 65 years and above,
* no communication problems,
* able to communicate in Chinese, and
* able to use an online meeting platform.

Exclusion Criteria:

* contraindications to chair-based exercises, and
* engagement in any kind of cognitive training three months prior to the study or during the study period.

Primary outcomes:
measure: Change from baseline subjective memory complaints at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline subjective memory complaints at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline subjective memory complaints at 18 weeks
timeFrame: 18 weeks after baseline
Secondary outcomes:
measure: Change from baseline cognitive status at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline cognitive status at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline cognitive status at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline working memory at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline working memory at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline working memory at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline executive function at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline executive function at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline executive function at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline lower-limb muscle strength at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline lower-limb muscle strength at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline lower-limb muscle strength at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline happiness at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline happiness at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline happiness at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline depressive symptoms at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline depressive symptoms at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline depressive symptoms at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline social isolation/integration at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline social isolation/integration at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline social isolation/integration at 18 weeks
timeFrame: 18 weeks after baseline
measure: Change from baseline instrumental activity of daily living at 6 weeks
timeFrame: Six weeks after baseline
measure: Change from baseline instrumental activity of daily living at 12 weeks
timeFrame: 12 weeks after baseline
measure: Change from baseline instrumental activity of daily living at 18 weeks
timeFrame: 18 weeks after baseline
Other outcomes:
Locations:
city: Hong Kong
country: Hong Kong
facility: Nursing Home
Study officials:
affiliation: School of Nursing, The University of Hong Kong
name: Pui Hing Chau, PhD
role: PRINCIPAL_INVESTIGATOR
References: