Clinical trial NCT02197689: A Trial for a Personalized Medication Management Platform to Improve Medication Adherence
Official title: Mobile Intelligent Personal Medication Management Platform
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Patients Take Medicine
Keywords: Personalized Medication Management
Medication Adherence
SMS Medication Reminder
Lead sponsor: Taipei Medical University
Sponsor class: OTHER
Collaborators: name: National Science and Technology Council, Taiwan
name: Taipei Veterans General Hospital, Taiwan
name: China Medical University, Taiwan
name: Taipei Medical University WanFang Hospital
name: National Yang Ming Chiao Tung University
name: National Chung Cheng University
name: National Tsing Hua University, HsinChu City, Taiwan
name: National Taiwan University
name: Hwa Hsia Institute of Technology, New Taipei City, Taiwan
First posted: 2014-07-23
Enrollment: 763
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Taiwan has attracted much attention for its National Health Insurance (NHI) and healthcare system around the world with many countries in Europe and the United States using it as a benchmark. However, increasing medication costs over the past two years account for more than 25% of total expenditure, surpassing every OECD member and mounting increasing pressure on the NHI. Nevertheless, patient medication adherence is relatively low. Thus, the investigators assessed the effectiveness of a personalized medication management system for improving the medication adherence for patients, in order to save long term medication costs.

Detailed description: Design, Setting and Patients: The investigators developed a mobile personalized medication management platform (PMMP) to reduce delayed and missed medications. The investigators conducted a randomized control trial in medical centers of northern Taiwan from January 2010 to July 2012 using 1198 participants that missed or delayed their medications during past three days. They received a minimum 7-day to 14-day maximum medication prescription.

Interventions: Patients were randomized into a control group which non-received any SMS reminder for medication using and an intervention group which received a SMS reminder everyday in mobile devices.

Primary Outcome(s) and Measure(s): The primary outcomes were compared patient medication adherence among experimental and control groups.

Eligibility criteria: Inclusion Criteria:

* Delayed or forgot to take medications over the last 3 days
* Received a min. 7-day medication prescription
* Able to receive SMS using mobile phones / devices
* 20 years or older
* Having intention to receive active treatment

Exclusion Criteria:

* Unable to receive SMS via mobile phones
* Illiterate and \< 20 years of age
* Received outpatient prescription drugs for ≤ 7 days
* External use, injections and traditional Chinese medicine
* Planned to go abroad
* Cold, cough, or prescribed with analgesics

Primary outcomes:
measure: The proportion of patients in delaying and forgetting medications
timeFrame: Patients who participated in this trial will be sent SMS during 7days
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Taipei Medical University
name: Yu-Chuan Li, MD., PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Huang CY, Nguyen PA, Clinciu DL, Hsu CK, Lu JR, Yang HC, Wu CC, Tsai WC, Chou YC, Kuo TBJ, Chang PL, Jian WS, Li YJ. A personalized medication management platform (PMMP) to improve medication adherence: A randomized control trial. Comput Methods Programs Biomed. 2017 Mar;140:275-281. doi: 10.1016/j.cmpb.2016.12.012. Epub 2016 Dec 30.