Clinical trial NCT03722394: Pain Neuroscience Education for Acute and Sub-Acute Low Back Pain
Official title: Pain Neuroscience Education for Acute and Sub-Acute Low Back Pain: An Exploratory Case Series
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Low Back Pain
Pain, Chronic
Pain, Back
Lead sponsor: University of Nevada, Las Vegas
Sponsor class: OTHER
Collaborators: name: St. Ambrose University
First posted: 2018-10-26
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Observational cohort
Primary purpose: TREATMENT

Brief summary: To determine if Pain Neuroscience Education (PNE) would result in positive clinical changes in patients presenting with acute or sub-acute low back pain (LBP).

Detailed description: Background: Pain neuroscience education (PNE) has shown efficacy in treating chronic pain. Clinicians may believe PNE is not suitable for acute and sub-acute pain. Subgroupings of low back pain (LBP) imply some patients with LBP may respond favorably to PNE.

Objective: To determine if PNE would result in positive clinical changes in patients presenting with acute or sub-acute LBP.

Methods: Eighty consecutive patients with LBP \< 3 months were enrolled in the study. Patients completed a demographics questionnaire, leg and LBP rating (Numeric Pain Rating Scale - NPRS), disability (Oswestry Disability Index), fear-avoidance (Fear-Avoidance Beliefs Questionnaire), pain catastrophization (Pain Catastrophization Scale), central sensitization (Central Sensitization Inventory), pain knowledge (Revised Neurophysiology of Pain Questionnaire), risk assessment (Keele STarT Back Screening Tool), active trunk flexion and straight leg raise (SLR). Patients received a 15-minute verbal, one-on-one PNE session, followed by repeat measurement of LBP and leg pain (NPRS), trunk flexion and SLR.

Eligibility criteria: Inclusion Criteria:

* a complaint of LBP with or without leg pain less than 3 months, and
* a willingness to participate

Exclusion Criteria:

* a) were under age 18 (minor);
* b) had undergone lumbar surgery;
* c) could not read or understand the English language;
* d) presented with any cognitive deficits rendering them unsuitable for PNE (i.e., stroke, traumatic brain injury, etc.),
* e) declined to participate or
* f) presented with a medical etiology (red flag) associated with their LBP.

Primary outcomes:
measure: NPRS - LBP
timeFrame: Immediate change from baseline after assigned intervention
measure: NPRS - Leg pain
timeFrame: Immediate change from baseline after assigned intervention
Secondary outcomes:
measure: Active trunk flexion
timeFrame: Immediate change from baseline in centimeters after assigned intervention
measure: Passive Straight Leg Raise
timeFrame: Immediate change from baseline in angular degrees after assigned intervention
Other outcomes:
Locations:
city: Las Vegas
country: United States
facility: University of Nevada Las Vegas
state: Nevada
Study officials:
affiliation: St. Ambrose University
name: Kevin Farrell, PhD
role: PRINCIPAL_INVESTIGATOR
References: