Clinical trial NCT04141332: Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
Official title: Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Specific Language Impairment
Lead sponsor: Mansoura University Hospital
Sponsor class: OTHER
First posted: 2019-10-28
Enrollment: 160
Sex: ALL
Minimum age (years): 3
Maximum age (years): 6
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The study was conducted on 80 children with speech disorders in preschool children.

Brief summary: The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.

Detailed description: This study concentrates on the impact of epileptiform activity for childhood epilepsy on the speech and language disturbances in addition to the associated social, cognitive and intellectual dysfunctions.

Eligibility criteria: Inclusion Criteria:

* 80 children were suffering from specific language impairment
* 80 healthy children with age and sex match control group.

Exclusion Criteria:

* Previous history of perinatal hypoxic-ischemic damage
* meningitis or encephalitis
* motor weakness
* hearing disorders
* IQ below seventy
* CP, social deprivation
* autism and
* psychiatric disorders .

Primary outcomes:
measure: EEGs finding
timeFrame: 24-48 hours
Secondary outcomes:
Other outcomes:
measure: Intelligence quotient (IQ)
timeFrame: 24-72 hours
measure: social age
timeFrame: 24-48 hours
measure: cognitive age
timeFrame: 24-48 hours
measure: language assessment
timeFrame: 24-72 hours
Locations:
city: Mansoura
country: Egypt
facility: Mansoura University Hospital
state: Dakahlia
Study officials:
affiliation: Assistant Prof of Neurology
name: Esmael M Ahmed, MD
role: PRINCIPAL_INVESTIGATOR
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