Clinical trial NCT01788644: Early Child Care and Risk of Obesity
Official title: Nurture: Early Child Care and Risk of Obesity
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Child Adiposity
Keywords: Child adiposity
Infancy
Motor activity
Feeding behavior
Sleep
Stress, Physiological
Lead sponsor: Johns Hopkins University
Sponsor class: OTHER
First posted: 2013-02-11
Enrollment: 860
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Mothers/infant dyads in the Durham, NC area

Brief summary: The purpose of this study is to examine risk factors associated with infant growth and the development of obesity in the first year of life. The investigators plan to establish a racially and ethnically diverse southern cohort of 800 mother/infant dyads, followed regularly from birth to 12 months of age. The cohort will be residents of Durham, North Carolina (NC) and the immediate surrounding area. The proposed longitudinal study will examine factors contributing to the development of obesity, including dietary behaviors, physical activity and inactivity, stress, and sleep duration and quality. Frequent in-home assessments throughout infancy and contact with other care providers will help pinpoint exactly when children begin to gain weight excessively and will identify risk factors related to energy intake, energy expenditure, stress, and sleep associated with obesity.


Eligibility criteria: Inclusion Criteria:

* mother over 18
* in 2nd or 3rd trimester of pregnancy with singleton
* speak and read English
* planning to stay in area for the first year of baby's life

Exclusion Criteria:

* baby born with conditions that may affect weight, feeding or motor activity

Primary outcomes:
measure: Change in child adiposity
timeFrame: birth - 12 months
Secondary outcomes:
Other outcomes:
Locations:
city: Durham
country: United States
facility: Duke University Medical Center
state: North Carolina
Study officials:
References:
citation: Benjamin Neelon SE, Ostbye T, Bennett GG, Kravitz RM, Clancy SM, Stroo M, Iversen E, Hoyo C. Cohort profile for the Nurture Observational Study examining associations of multiple caregivers on infant growth in the Southeastern USA. BMJ Open. 2017 Feb 8;7(2):e013939. doi: 10.1136/bmjopen-2016-013939.
citation: Costa S, Adams J, Gonzalez-Nahm S, Benjamin Neelon SE. Childcare in Infancy and Later Obesity: a Narrative Review of Longitudinal Studies. Curr Pediatr Rep. 2017;5(3):118-131. doi: 10.1007/s40124-017-0134-7. Epub 2017 Jun 15.
citation: Khatiwada A, Shoaibi A, Neelon B, Emond JA, Benjamin-Neelon SE. Household chaos during infancy and infant weight status at 12 months. Pediatr Obes. 2018 Oct;13(10):607-613. doi: 10.1111/ijpo.12395. Epub 2018 Jul 17.
citation: Hesketh KR, Evenson KR, Stroo M, Clancy SM, Ostbye T, Benjamin-Neelon SE. Physical activity and sedentary behavior during pregnancy and postpartum, measured using hip and wrist-worn accelerometers. Prev Med Rep. 2018 Apr 19;10:337-345. doi: 10.1016/j.pmedr.2018.04.012. eCollection 2018 Jun.
citation: Emond JA, O'Malley AJ, Neelon B, Kravitz RM, Ostbye T, Benjamin-Neelon SE. Associations between daily screen time and sleep in a racially and socioeconomically diverse sample of US infants: a prospective cohort study. BMJ Open. 2021 Jun 24;11(6):e044525. doi: 10.1136/bmjopen-2020-044525.