Clinical trial NCT06962878: Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars
Official title: Assessment of Bone Volume Changes in Immediate Implant Placement Using Allograft Versus Xenograft in Mandibular Molars: Randomized Clinical Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Bone Volume
Immediate Implant With Bone Graft
Keywords: Bone graft
Jumping gap
Xenograft
Allograft
Immediate implant
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-05-08
Enrollment: 20
Sex: ALL
Minimum age (years): 20
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Twenty recruited patients indicated for immediate implant placement in mandibular molar sites are divided into two groups, with each group containing ten patients. One group assigned for placement of xenograft after molar extraction and immediate implant placement, while the other group received allograft as space-filling material.


Eligibility criteria: Inclusion Criteria:

* Patients with non-restorable mandibular molars
* Both sexes with age range from 20 years to 45 years
* Good oral hygiene
* Adequate alveolar bone dimensions for implant replacement
* Adequate bone volume after extraction to achieve primary stability of the immediate implant
* Co-operative patient

Exclusion Criteria:

* Patients with any systemic disease as uncontrolled diabetes or osteoporosis
* Heavy smokers with smokers more than 10 cigarettes per day
* Pregnancy
* Patients with any signs of active infection or pus formation
* Patients undergoing chemotherapy or radiotherapy, immunocompromised patients

Primary outcomes:
measure: Horizontal bone thickness in millimeters
timeFrame: 6 months postoperative
Secondary outcomes:
measure: Vertical bone height in millimeters
timeFrame: 6 months postoperative
measure: Pain intensity
timeFrame: One week postoperative
Other outcomes:
Locations:
Study officials:
affiliation: Cairo University
name: Mohamed Atef, PhD
role: STUDY_DIRECTOR
References:
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