Clinical trial NCT06609837: 30-Second Sit-to-Stand Test for Assessing Functional Capacity in Juvenile Idiopathic Arthritis
Official title: 30-Second Sit-to-Stand Test as an Alternative Tool for Assessing Functional Capacity in Patients With Juvenile Idiopathic Arthritis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Juvenile Idiopahtic Arthritis
Keywords: adolescents
Juvenile Idiopahtic Arthritis
functional capacity
Lead sponsor: Istanbul University - Cerrahpasa
Sponsor class: OTHER
First posted: 2024-09-24
Enrollment: 197
Sex: ALL
Minimum age (years): 12
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Individuals with JIA who come to Istanbul University Medical Faculty, Pediatric Rheumatology Clinic and meet the inclusion criteria for Usability and Validity Group Healthy adolescent participants aged 12-18 years

Brief summary: Juvenile Idiopathic Arthritis (JIA) is a heterogeneous, idiopathic, chronic inflammatory, rheumatic disease that is most common in childhood and is thought to involve immunological mechanisms in its etiopathogenesis. The physiology of children and adolescents is constantly changing due to the development and maturation of their systems. At the same time, the changes that this population shows, especially during the growth spurt and adolescence, can affect their performance in frequently used functional tests such as the 6-Minute Walk Test (6MWT). At the same time, it is emphasized that alternative tests are needed because the evaluation procedures of the 6MWT are not practical enough. The aim of this study is to investigate whether 30 Second Sit to Stand Test (30SST) is an alternative tool for assessing functional capacity in patients with JIA.

H0: 30SST is not an alternative tool for assessing functional capacity in patients with JIA.

H1: 30SST is an alternative tool for assessing functional capacity in patients with JIA.

The study will include 81 adolescent patients with oligoarticular/polyarticular JIA and 116 healthy adolescent between the ages of 12-18. The 6MWT, 30SST and 10 Stair Climb Test (10SCT) will be applied to the cases that meet the inclusion criteria to evaluate their functional capacity. Demographic data and test results of the participants will be recorded and evaluated with statistical analysis methods. We believe that alternative tests that can be used to evaluate functional capacity in patients with JIA will contribute to the literature as a result of this study.


Eligibility criteria: Inclusion Criteria:

* Being 12-18 years old for both groups
* Having been diagnosed with JIA at least 6 months ago at the Istanbul Medical Faculty Pediatric Rheumatology Clinic for Usability and Validity Group
* Having a diagnosis of Oligoarticular/Polyarticular JIA for Usability and Validity Group
* Volunteer to participate in the study for both groups

Exclusion Criteria:

* History of trauma or surgery affecting the musculoskeletal system within the last 6 months
* Having an additional chronic disease affecting the musculoskeletal system for both groups
* Having vision or hearing problems for both groups
* Having cognitive impairment at a level where the person cannot understand the commands given for both groups
* Having vision or hearing problems for both groups
* Having had a corticosteroid injection into the knee or ankle within the last week for both groups
* Difference in length in the lower extremities for both groups

Primary outcomes:
measure: 6 Minute Walk Test (6 MWT)
timeFrame: Time Frame: Baseline
measure: 30 Second Sit to Stand Test (30SST)
timeFrame: Time Frame: Baseline
measure: 10 Stairs Climb Test (10SCT)
timeFrame: Time Frame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul University-Cerrahpaşa
Study officials:
affiliation: Istanbul University - Cerrahpasa
name: Nilay Arman, Assoc. Prof.
role: STUDY_DIRECTOR
affiliation: Fenerbahçe University
name: Asena Yekdaneh, MSc. Pt.
role: PRINCIPAL_INVESTIGATOR
affiliation: Istanbul University - Cerrahpasa
name: Asya Albayrak, MSc. Pt.
role: PRINCIPAL_INVESTIGATOR
affiliation: Istanbul University
name: Fatma Gül Demirkan, Dr.
role: PRINCIPAL_INVESTIGATOR
affiliation: Istanbul University
name: Özlem Akgün, Assoc. Prof.
role: PRINCIPAL_INVESTIGATOR
affiliation: Istanbul University
name: Nuray Aktay Ayaz, Prof.
role: PRINCIPAL_INVESTIGATOR
References: