Clinical trial NCT03964285: Repetitive Thinking in Fibromyalgia
Official title: Impact of Rumination on Affectivity After Physical Activity in Fibromyalgia
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Rumination
Fibromyalgia
Chronic Pain
Repetitive Negative Thinking
Keywords: Rumination
Fibromyalgia
Chronic Pain
affectivity
repetitive negative thinking
Lead sponsor: Centre Hospitalier Universitaire, Amiens
Sponsor class: OTHER
Collaborators: name: Université de Lille
First posted: 2019-05-28
Enrollment: 47
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Some fibromyalgia patients may use inappropriate emotional regulation strategies to respond to pain. Rumination could be one of this inefficient regulation strategies. The investigators believe that the use of rumination strategies to respond to the discomfort of daily physical activity would maintain and aggravate a negative emotional state after the effort. Distraction would be a more effective strategy to cope with pain. From this data, the investigators want to explore the causal link between rumination and negative affectivity after physical activity in fibromyalgia using an experimental design.

Detailed description: Fibromyalgia is a disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory and mood issues. As with any condition of chronic pain, psychological mechanisms can help maintain discomfort and pain. These mechanisms may hinder the recovery of physical activity. Some patients may use cognitive strategies of emotional regulation that are ineffective to cope with pain and discomfort of everyday activities, such as rumination. The literature suggests that this process is linked to the physical and psychological difficulties of fibromyalgia. However, no study has revealed a causal link between rumination and negative affectivity in a context of physical activity in this population. The investigators want to test this hypothesis by directly manipulating the style of information processing following a relevant activity for these patients: climbing steps. In one group the investigators will induce rumination right after climbing the steps. In the other group the investigators will induce distraction. Patient with Fibromyalgia will be recruited at the Pain Center of CHU-Amiens. Patients will complete different scales before to climb steps and after experimental induction. The investigators hypothesize that Patients using a rumination strategy after an uncomfortable physical activity will experience a greater subjective discomfort than patients using a distraction strategy.

Eligibility criteria: Inclusion Criteria:

* Adults Patients
* Free and informed consent signed.
* French native speaker, writer and reader.
* according 1990 American College of Rheumatology criteria : Patients with diffuse pain for more than three months and with digital palpation pain on more than 11 insertion points.

Exclusion Criteria:

* minor patients
* Adult major under administrative protection
* Patient with severe psychosis or depression or severe anxiety or impulsivity as assessed by the clinician

Primary outcomes:
measure: Change in PANAS score before and after induction phase
timeFrame: One hour and twenty minutes after inclusion of the patients
Secondary outcomes:
measure: Change in VAS score before and after induction phase
timeFrame: One hour and twenty minutes after inclusion of the patients
Other outcomes:
Locations:
city: Amiens
country: France
facility: CHU Amiens
Study officials:
affiliation: CHU Amiens
name: Eric Serra, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: CHU Amiens
name: Virginie Marechal, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: CHU Amiens
name: Alain DERVAUX, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: CHU Amiens
name: Jérémy Fonseca Das Neves, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Lille University
name: Stéphane Rusinek, PHD
role: PRINCIPAL_INVESTIGATOR
References: