louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02422680: Patient Satisfaction With Colonoscopy in a Danish Setting - What Are the Most Important Factors?
Official title: Patient Satisfaction With Colonoscopy in a Danish Setting - What Are the Most Important Factors?
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Colorectal Cancer
Keywords: Quality assurance
Caecum intubation rate
Patient satisfaction
Lead sponsor: Aalborg University Hospital
Sponsor class: OTHER
Collaborators: name: Nordsim
First posted: 2015-04-21
Enrollment: 0
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients referred to colonoscopy at the out patient clinic at Aalborg University department. All patients deemed fit to for at colonoscopy at the outpaient clinic were included. The patient population is a mix of screening and non-screening patients. The study begins in april 2015.

Brief summary: The study aim is to investigate factors associated with patient satisfaction during a colonoscopy.

Detailed description: The study aim to capture key quality indicators and patient satisfaction for 800 patients referred for a colonoscopy at Aalborg University Hospital. The patient population is mix of screening and non-screening colonoscopies seen at our out-patient clinic.

Each Colonoscopy is registered using a specially designed registration form and a more detailed form relating to the colonoscopy itself. The data collected includes: The Colonoscopist endoscopy experience and education, Medicine use, Colonoscopy duration, Unadjusted Caecum Intubations rate, Polyp detection rate, Polyps removed, Cancer detection rate and Nurse assisted Gloucester Comfort score.

Patient level data were recorded using a questionaire with 6 questions regarding satisfaction, pain, discomfort etc on a 10 cm analog scale.

Eligibility criteria: Inclusion Criteria:

* All patients referred to colonoscopy at the out-patient clinic at Aalborg University department.

Exclusion Criteria:

* Rejection to fill out questionaire.
* Patents referred to AVA (advanced endoscopy unit) were excluded as the are not comparable to regular colonoscopies. Most patients are referred to AVA for specific endoscopy treatments such as large polyp removals etc.

Primary outcomes:
measure: Patient Satisfaction
timeFrame: 1 day
Secondary outcomes:
measure: Nurses perception of patients' pain
timeFrame: 1 day
measure: Patient Pain (own Perception)
timeFrame: 1 day
Other outcomes:
Locations:
city: Aalborg
country: Denmark
facility: NordSim, Aalborg University Hospital
Study officials:
affiliation: Aalborg University Hospital, Surgical Department.
name: Lasse Pedersen, m.d.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Chartier L, Arthurs E, Sewitch MJ. Patient satisfaction with colonoscopy: a literature review and pilot study. Can J Gastroenterol. 2009 Mar;23(3):203-9. doi: 10.1155/2009/903545.
Clinical trial NCT00646880: A Study to Evaluate the Efficacy of Tolterodine Prolonged Release Compared With Propiverine for the Treatment of Korean Patients With Overactive Bladder as Assessed by Ambulatory Urodynamic Monitoring
Official title: Double-Blind Crossover Comparative Ambulatory Urodynamic Monitoring (AUM) Study of Tolterodine PR and Propiverine in Korean Patients With Overactive Bladder (OAB)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Urinary Bladder, Overactive
Lead sponsor: Pfizer
Sponsor class: INDUSTRY
First posted: 2008-03-31
Enrollment: 41
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to compare the difference between tolterodine prolonged release (PR) and propiverine in efficacy as assessed by the AUM and to show that tolterodine PR is similar to propiverine with respect to micturition chart variables and safety profile.


Eligibility criteria: Inclusion Criteria:

* Symptoms of urinary urgency
* Symptoms of urinary frequency (greater than or equal to 8 micturitions per 24 hours) as verified on the patient's micturition chart
* Symptoms of overactive bladder for greater than or equal to 6 months

Exclusion Criteria:

* Stress incontinence as determined by the investigator and confirmed for female patients by a cough provocation test
* An average volume voided of \>200 ml per micturition as verified on the micturition chart before randomization
* Total daily urine volume of \>3000 ml as verified on the micturition chart before randomization

Primary outcomes:
measure: Parameters of detrusor activity, occurring throughout the duration of comparable AUM
timeFrame: 28 days
Secondary outcomes:
measure: Number of pads used per 24 hours
timeFrame: 28 days
measure: Urge Incontinence
timeFrame: 28 days
measure: Number of urgency episodes
timeFrame: 28 days
measure: Number of micturitions per 24 hours
timeFrame: 28 days
measure: Volume voided per micturition
timeFrame: 28 days
measure: Patient's perception of bladder condition
timeFrame: 28 days
measure: Patient's perception of treatment benefit
timeFrame: 28 days
measure: Patient's perception of urgency
timeFrame: 28 days
measure: The occurrences of adverse events and withdrawals and changes in laboratory variables over each 1-week treatment period.
timeFrame: 42 days
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Pfizer Investigational Site
Study officials:
affiliation: Pfizer
name: Pfizer CT.gov Call Center
role: STUDY_DIRECTOR
References:
Clinical trial NCT05428280: Comparing the Effects of Muscle Energy Technique Versus Myofascial Mobilization in Managing Sub-acute Low Back Pain
Official title: Effectiveness of Muscle Energy Technique Versus Myofascial Mobilization in Improving Functional Outcome in Sub-acute Non-specific Low Back Pain: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Lordosis
Low Back Pain
Lead sponsor: Dow University of Health Sciences
Sponsor class: OTHER
First posted: 2022-06-23
Enrollment: 60
Sex: ALL
Minimum age (years): 30
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Institute for Clinical Systems Improvement (ICSI) defines sub-acute low back pain as low back pain lasting between 4 and 12 weeks. There is insufficient evidence regarding the comparative effect of muscle energy technique and myofascial mobilization in the management of sub-acute non-specific low back pain with the tightness of quadratus lumborum and erector spinae muscles

Detailed description: A randomized experimental controlled trial will be carried out to compare the effectiveness of muscle energy technique and myofascial mobilization in the management of sub-acute non-specific low back pain. A total of 60 male and female volunteers having subjects with sub-acute nonspecific low back pain will be recruited in this study. Subjects will be assessed at baseline for pain and disability using Visual Analogue Scale and Ronald Morris Disability Questionnaire (RMDQ 0-24) respectively. After baseline assessment, all subjects will be allocated to two groups through computer-generated random sampling. Group 1 will perform Muscle energy technique combined with conventional exercise; Group 2 will receive Myofascial Mobilization combined with conventional exercise. This study will be conducted at the Physiotherapy Department of Sindh Institute of Physical Medicine and Rehabilitation (SIPM\&R). Data will be analyzed using SPSS 21 and ANCOVA technique will be used in this study.

Eligibility criteria: Inclusion Criteria:

* Sub-acute low back pain with the range of 7 to 12 weeks of unresolved symptoms.
* Positive test of tight Erector spinae muscle and Tight Quadratus Lumboram muscle

Exclusion Criteria:

* Spinal malignancy
* Spinal fracture
* Spine foraminal stenosis
* Nerve root compression
* Radicular symptoms
* Sciatica
* Cord compression
* Paralysis
* Muscular dystrophy
* Myelopathy
* Seizure disorder
* Severe trauma
* Unexplained weight loss

Primary outcomes:
measure: Visual Analogue Scale
timeFrame: Change from baseline pain intensity at 4 weeks
measure: Rolland Morris Disability Questionnaire
timeFrame: Change from baseline functional disability at 4 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: Sindh Institute of Physical Medicine and Rehabilitation
state: Sindh
Study officials:
affiliation: Sindh Institute of Physical Medicine and Rehabilitation
name: Faizan Abdullah, MSAPT, DPT
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06472180: Sectional Versus Full Glass Ceramic Laminate Veneers
Official title: Marginal Adaptation, Color Stability and Clinical Performance of Sectional and Full Glass Ceramic Laminate Veneers. A Randomized Clinical Trial
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Spacing of Anterior Teeth
Keywords: Mini-veneers
partial veneers
porcelain fragments
sectional veneers
laminate veneers
Lead sponsor: October University for Modern Sciences and Arts
Sponsor class: OTHER
First posted: 2024-06-25
Enrollment: 22
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study is to assess the marginal adaptation, color stability and clinical performance of glass ceramic sectional veneers compared to full laminate veneers There's two null hypotheses , the first is that there is no difference in the marginal adaptation of sectional and full glass ceramic laminate veneers.

the Second is that there is no apparent change in color stability and clinical performance of sectional and full glass ceramic laminate veneers.

Detailed description: Although seeking for more minimally invasive treatment modalities with the use of the new advancements in ceramics and adhesive materials, however there is insufficient clinical studies assessing the ultraconservative sectional veneers has been published although there are many published case reports proving their success .

Hence the aim of this study is to assess the sectional veneers compared to laminate veneer regarding marginal adaptation, color stability and clinical performance

Eligibility criteria: Inclusion Criteria:

* Patients seeking for esthetics with the following criteria
* Male or female patients age range above 18 years old
* Minor esthetic defects in anterior region
* Multiple spacing
* diastemas
* Incisal fracture
* Initial proximal caries
* Patients able physically and psychologically to tolerate restorative procedures
* Patients willing to return for follow-up examinations and evaluation
* Class I occlusion

Exclusion Criteria:

* Patients free of:
* Tempromandibular disorders
* Para-functional habits
* Cracked teeth
* Moderate or deep caries
* Heavily discolored teeth
* Heavy smokers
* Enamel defects compromising bonding
* Active periodontal disease
* Pulpal disease
* Mobility
* Occlusal disturbances
* Class II and III occlusion

Primary outcomes:
measure: Marginal adaptation of sectional and full glass ceramic laminate veneer using digital device intraoral scanner
timeFrame: Baseline,3,6,9,12 months
Secondary outcomes:
measure: Color stability
timeFrame: Baseline,3,6,9,12 months
measure: Clinical performance
timeFrame: Baseline,3,6,9,12 months
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: October University for Modern Sciences & Arts
state: Giza, 6th October City
Study officials:
affiliation: October University for Modern Sciences & Arts
name: Nehal G Mohamed, BDS
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01042080: Neurally Adjusted Ventilatory Assist and Synchrony in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Official title: Effect of Mechanical Ventilation With NAVA and PSV on Inspiratory Muscle Workload and Synchrony in Patients With Chronic Obstructive Pulmonary Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: Mechanical ventilation
Neurally adjusted ventilatory assist (NAVA)
Acute respiratory failure
Chronic obstructive pulmonary disease
Weaning
Invasive mechanical ventilation
Positive Pressure support Ventilation
Lead sponsor: Hôpital Européen Marseille
Sponsor class: OTHER
First posted: 2010-01-05
Enrollment: 16
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: SUPPORTIVE_CARE

Brief summary: NAVA used the electrical activity of the diaphragm (EAdi) to initiate and deliver in proportion of an inspiratory assistance. During inspiration, EAdi signal occurred earlier than airflow or pressure variations in the airway. The investigators hypothesized that NAVA improved patient-ventilator synchrony and reduced inspiratory workload as compared with pressure support ventilation delivered at two different cycling criteria (25 and 50 %).


Eligibility criteria: Inclusion Criteria:

* History of chronic obstructive pulmonary disease
* Admitted for acute respiratory failure requiring invasive mechanical ventilation
* Currently receiving pressure support ventilation

Exclusion Criteria:

* Age \< 18 years
* Respiratory rate \> 35 bpm
* Severe hypoxemia with SpO2 \< 88 % and FIO2 \> 50 %
* Heart rate \> 120 bpm
* Systolic arterial pressure \< 90 mmHg
* Contraindication to naso-gastric tube's insertion

Primary outcomes:
measure: Inspiratory muscle workload as reflected by the diaphragmatic Pressure Time Product (PTPdi)
timeFrame: 5 minutes
Secondary outcomes:
measure: Ineffective inspiratory effort
timeFrame: 5 minutes
measure: Dynamic intrinsic PEEP
timeFrame: 5 minutes
measure: Arterial blood gases
timeFrame: 20 minutes
measure: Trigger delay
timeFrame: 5 minutes
Other outcomes:
Locations:
city: Marseille
country: France
facility: Hopital Paul Desbief
city: Marseille
country: France
facility: Fondation Hôpital Ambroise Paré
Study officials:
affiliation: Fondation Hôpital Ambroise Paré
name: Jérôme ALLARDET-SERVENT, MD, MSc
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03773380: Breathe Anew for Lung Cancer Survivorship
Official title: Breathe Anew: Designing and Testing the Feasibility of a Novel Intervention for Lung Cancer Survivorship
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Lung Cancer
Lead sponsor: St. Joseph's Healthcare Hamilton
Sponsor class: OTHER
First posted: 2018-12-12
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: Survivorship programs have become an integral component of modern cancer care programs. In Canada, there has been tremendous success for survivorship programs for breast, prostate, and colorectal cancer, however lung cancer survivorship programs have not been widely developed. The complexity of the disease, high mortality, short survival times, high cost of surveillance, and patient habits have traditionally been barriers against the success of lung cancer survivorship programs. The investigator proposes a feasibility study to pilot a novel intervention titled Breathe Anew, which will aim to identify and overcome the barriers to the design and implementation of a lung cancer survivorship program. The investigator has assembled a multi-disciplinary team of experts and lung cancer survivors who will develop the Breathe Anew survivorship intervention. The intervention will be vetted using an integrated knowledge translation approach, which will involve members of the target population, primarily patients who previously underwent lung resection, to modify the intervention and ensure acceptability. After Breathe Anew has been designed, it will be tested in a pilot study of 50 patients to ensure its feasibility and determine its cost. The ultimate goal of this feasibility study is to lay the groundwork for a subsequent comparative trial to evaluate the impact of Breathe Anew on patient-important outcomes including health related quality and length of life and postoperative complications.


Eligibility criteria: Inclusion Criteria:

* Age 18 years or older
* All patients at St. Joseph's Healthcare Hamilton who received lung resection for Stage I, Stage II, or Stage IIIa Non-Small Cell Lung Cancer are eligible to enroll.
* Owns a smart device

Exclusion Criteria:

* Patients who received lung resection for Stage IIIb or IV Non-Small Cell Lung Cancer
* Patients with affected mobility (walker, wheelchair)
* Patients who use oxygen at home

Primary outcomes:
measure: Compliance
timeFrame: 12 months
Secondary outcomes:
measure: Accrual Rate
timeFrame: 12 months
measure: Patient-Reported Satisfaction
timeFrame: 12 months
measure: Cost Per Patient
timeFrame: 12 months
Other outcomes:
Locations:
city: Hamilton
country: Canada
facility: St. Joseph's Healthcare Hamilton
state: Ontario
Study officials:
References:
Clinical trial NCT03525080: Comparison of 6-fluoro-[18F]-L-dihydroxyphenylalanine (18F-DOPA) Positron Emission Tomography (PET) and Multiparametric Resonance Magnetic Imagery (RMI) in Initial Exploration of Glial Tumors
Official title: Diagnostic Assessment Study, Single Site and Prospective, comparing18F-DOPA PET and Multiparametric RMI in Initial Exploration of Diffuse Glial Tumors
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Brain Neoplasms
Adult Brain Tumor
Lead sponsor: Center Eugene Marquis
Sponsor class: OTHER
First posted: 2018-05-15
Enrollment: 16
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: For patient having a brain tumor, RMI is the standard exam for tumor characterization and determines initial surgery.

The aim of this study is to assess if PET could provide additional information that could have an impact on surgery (indication and planification)


Eligibility criteria: Inclusion Criteria:

* Suspected glial resectable tumor
* Free and informed consent
* Affiliated to French social security

Exclusion Criteria:

* Suspected high grade glioma
* Surgical emergency
* Pregnant or breastfeeding woman
* Patient deprived of their liberty or under guardianship
* Patient not able to follow study medical monitoring for geographical, social or psychological reasons
* Treated with carbidopa, catechol-O-methyl transferase inhibitor, haloperidol, reserpine within 2 weeks before PET imagery

Primary outcomes:
measure: PET pictures and MRI sequences comparison
timeFrame: Imagings performed up to 29 days after inclusion (before brain surgery)
Secondary outcomes:
Other outcomes:
Locations:
city: Rennes
country: France
facility: Centre Eugène Marquis
state: Bretagne
Study officials:
affiliation: Centre Eugène Marquis
name: Florence LE JEUNE, Professor
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03876080: Dry Needling in Subjects With Delayed Onset Muscle Soreness
Official title: Biomechanical Response to Dry Needling in Subjects With Delayed Onset Muscle Soreness: a Double Blind Randomized Control Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Delayed Onset Muscle Soreness
Lead sponsor: Bradley University
Sponsor class: OTHER
First posted: 2019-03-15
Enrollment: 36
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Investigation of the biomechanical response in delayed onset muscle soreness using dry needling vs. sham


Eligibility criteria: Inclusion Criteria:

* The participants of the study will be any healthy male or female between
* age of 18 to 35
* able and willing to perform an exercise protocol using the gastrocnemius muscle
* willing to receive either sham or dry needling intervention

Exclusion Criteria:

* current muscular pain
* prior trigger point therapy in the past 6 months
* medications that affect muscle function
* injury in the past 6 months
* any health condition that prevents exercising
* recent surgery

Primary outcomes:
measure: Change in Biomechanical stiffness (N/m) using MyotonPRO
timeFrame: baseline, immediately after intervention, 24 hours after intervention
Secondary outcomes:
measure: Change in Pressure pain threshold using pressure algometry
timeFrame: baseline, immediately after intervention, 24 hours after intervention
Other outcomes:
Locations:
city: Peoria
country: United States
facility: Bradley University
state: Illinois
Study officials:
References:
Clinical trial NCT01328080: Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy
Official title: Improving Acne Keloidalis Nuchae by Inducing Matrix Metalloproteinases in Vivo Using Targeted Ultraviolet-B Irradiation
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Acne Keloidalis Nuchae
Lead sponsor: Johns Hopkins University
Sponsor class: OTHER
Collaborators: name: Skin of Color Society
First posted: 2011-04-04
Enrollment: 11
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study is being done to evaluate the effect of targeted UV-B (a component of sunlight) on the treatment of acne keloidalis nuchae (AKN, or razor bumps on the back of the neck). The investigators believe targeted UV-B is a safe and effective way to reduce the appearance of AKN.


Eligibility criteria: Inclusion Criteria:

* age 18 or over
* male gender
* African-American or other black ethnicity
* current diagnosis of acne keloidalis nuchae (razor bumps on back of neck)

Exclusion Criteria:

* allergy to lidocaine or numbing medicine
* history of increased sensitivity to sunlight, lupus, or porphyria
* current use of a drug that increases sensitivity to sunlight

Primary outcomes:
measure: Percentage Change in Total AKN Lesions From Baseline to Week 16.
timeFrame: Baseline to Week 16
Secondary outcomes:
Other outcomes:
Locations:
city: Baltimore
country: United States
facility: Johns Hopkins Dept. of Dermatology
state: Maryland
Study officials:
References: