Clinical trial NCT04645628: Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam
Official title: Optimization of the Acquisition Sequence to Improve the Quality and Comfort of Magnetic Resonance Imaging Exam
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Healthy Subjects
Patient Performing an MRI Examination
Lead sponsor: Central Hospital, Nancy, France
Sponsor class: OTHER
First posted: 2020-11-27
Enrollment: 720
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: The purpose of this study is to evaluate the optimization of MRI acquisition sequences.


Eligibility criteria: Inclusion Criteria for all subjects :

* to be over 18 year-old,
* to be able to understand the instructions given,
* to be enrolled in a social security plan,
* to have underwent a pre-inclusion medical examination,
* to give a written consent.

Inclusion Criteria especially for Patients :

* to perform a MRI examination of the head, neck, spine, thorax, abdomen, pelvis, retroperitoneum, lower limbs, upper limbs or whole body during clinical follow-up care.

Exclusion Criteria for all subjects :

* any contraindication to MR examination (active medical device, ferromagnetic foreign body, pregnancy, morbid obesity, claustrophobia, ... ),
* subject under a measure of legal protection.

Exclusion Criteria especially for Healthy Subjects :

* to have a pathology in the anatomical area to be imaged
* to be employed by the CHRU of Nancy or having the slightest link of subordination with the CHRU of Nancy.

Exclusion Criteria especially for Patients :

* to have a limited MRI examination time due to a sensitive clinical situation (sedation, unstable hemodynamic state, postoperative).

Primary outcomes:
measure: Image quality based on standard imaging quality criteria.
timeFrame: 6 months after the last inclusion
Secondary outcomes:
measure: Comparison of the Signal to Noise Ratio obtained by the optimized MRI sequence and the reference situation (standard sequence).
timeFrame: 6 months after the last inclusion
measure: Comparison of the Contrast to Noise Ratio obtained by the optimized MRI sequence and the reference situation (standard sequence).
timeFrame: 6 months after the last inclusion
measure: Comparison of the acquisition time obtained with the optimized MRI sequence and the reference situation (standard sequence).
timeFrame: 6 months after the last inclusion
measure: Comparison of blurring and artefacts obtained by the optimized MRI sequence and the reference situation (standard sequence).
timeFrame: 6 months after the last inclusion
measure: Comparison of the spatial resolution obtained by the optimized MRI sequence and the reference situation (standard sequence).
timeFrame: 6 months after the last inclusion
measure: Qualification of the MRI acquisition for a clinical study.
timeFrame: 6 months after the inclusion
measure: Evaluation of intra-subject reproducibility on the same MRI and on two MRIs.
timeFrame: 6 months after the last inclusion
Other outcomes:
Locations:
city: Nancy
country: France
facility: CHRU de Nancy
Study officials:
References: