louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT05487872: Mindfulness and Psychological Inflexibility
Official title: Mindfulness Skills Training and Psychological Inflexibility: a Randomized Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Mindfulness
Lead sponsor: Bahcesehir Cyprus University
Sponsor class: OTHER
First posted: 2022-08-04
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: This study aimed to examine whether mindfulness skills training can help to reduce experiential avoidance and anxiety level. This study investigated whether the training delivery methods (audio-guided mindfulness exercise or virtual reality-based mindfulness exercise) differ in terms of changing general experiential avoidance and anxiety symptoms.

Detailed description: The experimental design (randomized trial) was used in this study. Data were collected through convenience sampling. After obtaining ethical approval fromEthics Committee of the Bahçeşehir Cyprus University, participants were invited to participate in the study via advertisements posted in the university building. Recruited participants were randomly assigned to the experimental group or control group. All participants will be provided with an informed consent form which provided information about participant's right and data management. Participants in the experimental group completed mindfulness exercise on Virtual Reality (VR) system where they listened to an audio track (guide for the exercise) and saw calming nature scenes (e.g., views on the beach) whereas those in the control group completed mindfulness exercise by listening to the (same) audio track only. Each mindfulness session took approximately 15 mins. In total, four sessions were completed in two weeks (2 sessions per week). After obtaining informed consent, the participants completed a survey pack that included valid and reliable measurement scales (mindfulness skills \[The Cognitive and Affective Mindfulness Scale - Revised\], experiential avoidance \[Acceptance and Action Questionnaire-II\], and anxiety symptoms \[Generalized Anxiety Disorder Scale\]) at two-time points (i.e., pre-test \[before intervention\], and post-test \[after 4 sessions/when sessions were completed\], At the end of the study, the participants were provided with a debrief form.

Eligibility criteria: Inclusion Criteria:

* age of 18 and above,
* ability to read, and/or understand English

Exclusion Criteria:

* Participants who regularly practice mindfulness exercise were excluded form the analyses

Primary outcomes:
measure: Change in experiential avoidance
timeFrame: at two time points (pre-intervention and immediately after the intervention)
Secondary outcomes:
measure: Change in anxiety
timeFrame: at two time points (pre-intervention and immediately after the intervention)
Other outcomes:
Locations:
city: Nicosia
country: Cyprus
facility: Bahçeşehir Cyprus University
Study officials:
affiliation: Bahcesehir Cyprus University
name: Buse Keskindag
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01037972: Influence of Whole Body Vibration Compared to Conventional Physiotherapy in Patients With Gonarthrosis
Official title: Influence of Whole Body Vibration Compared to Conventional Physiotherapy in Patients With Gonarthrosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Osteoarthritis
Keywords: Galileo
Whole body vibration
Osteoarthritis
Knee
Physiotherapy
Lead sponsor: University of Cologne
Sponsor class: OTHER
First posted: 2009-12-23
Enrollment: 40
Sex: ALL
Minimum age (years): 30
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients with osteoarthritis of the knee.

Brief summary: 40 patients with osteoarthritis of the knee will be randomly assigned to conventional physiotherapy on the one and whole body vibration exercises on the other hand. The duration of the training will be 6 weeks, three times a week.

The outcome will be measured by WOMAC and SF-12 scores relating to pain and quality of life. The second outcome criteria will be a motion analysis and balance testing before and after the training.

The follow-up is 26 weeks.


Eligibility criteria: Inclusion Criteria:

* 30-80 years old
* WOMAC 30-70 mm (VAS)
* Gonarthrosis (Kellgren/Lawrence) II-III

Exclusion Criteria:

* WOMAC \>70 mm (VAS)
* Endoprosthesis in lower extremity
* BMI \>40 kg/m2

Primary outcomes:
measure: Pain Reduction
timeFrame: 6 weeks after inclusion
Secondary outcomes:
measure: Motion analysis
timeFrame: 6 weeks after inclusion
measure: Pain reduction
timeFrame: 12 weeks after inclusion
measure: Pain reduction
timeFrame: 26 weeks after inclusion
measure: Motion analysis
timeFrame: 12 weeks after inclusion
measure: Motion analysis
timeFrame: 26 weeks after inclusion
measure: Quality of life
timeFrame: 6 weeks after inclusion
measure: Quality of life
timeFrame: 12 weeks after inclusion
measure: Quality of life
timeFrame: 26 weeks after inclusion
Other outcomes:
Locations:
city: Cologne
country: Germany
facility: University Hospital of Cologne
Study officials:
affiliation: University of Cologne
name: Kourosh Zarghooni, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Cologne
name: Gregor Stein, MD
role: STUDY_DIRECTOR
References:
citation: Stein G, Knoell P, Faymonville C, Kaulhausen T, Siewe J, Otto C, Eysel P, Zarghooni K. Whole body vibration compared to conventional physiotherapy in patients with gonarthrosis: a protocol for a randomized, controlled study. BMC Musculoskelet Disord. 2010 Jun 21;11:128. doi: 10.1186/1471-2474-11-128.
Clinical trial NCT06900972: Effect of Colloids Versus Crystalloids on Heart Mechanics: a Double-blind Cross Over Randomized Trial
Official title: Effect of Colloids Versus Crystalloids on Heart Mechanics: a Double-blind Cross Over Randomized Trial
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: PHASE3
Conditions: Fluid Reponsiveness
Fluid Resuscitation
Fluid Therapy
Keywords: colloids
cristalloids
heart mechanics
Lead sponsor: University of Monastir
Sponsor class: OTHER
First posted: 2025-03-28
Enrollment: 16
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: The debate over whether to use colloid or crystalloid solutions for fluid resuscitationis still ongoing. Colloid solutions consist of large molecules that generally cannot pass through healthy capillary membranes, whereas crystalloid solutions contain ions that easily move from the intravascular space to the interstitial compartment. Therefore, it is traditionally argued that colloids are more effective at expanding intravascular volume, with a suggested ratio of 1:3 compared to crystalloids. However, there is currently limited evidence to suggest that resuscitation with one type of fluid is more effective or safer than t he other. Despite these theoretically advantageousphysiological properties, colloids have not demonstrated a clear hemodynamic benefit over crystalloids. We hypothesized that these unexpected discrepancies may be attributed to different mechanical heart responses.


Eligibility criteria: Inclusion Criteria:

* HealthyVolunteers with age \> 18 years without medical history

Exclusion Criteria:

History of cardio vascular diseases Diabetes Hypertension Currentpregnancy Knownallergy to one of the tested products Leftventricular dysfunction discovered at baseline assessment Valvular heart or other structural diseases discovered at base line assessment

Primary outcomes:
measure: Heart mechanics response will be assessed by using left ventricular longitudinal strain, left ventricular torsion strain curves, left atrial strain curves and right ventricular free wall strain curves
timeFrame: 1 day
Secondary outcomes:
Other outcomes:
Locations:
city: MOnastir
country: Tunisia
facility: Fattouma Bourguiba Hospital
Study officials:
References:
citation: Myburgh JA, Mythen MG. Resuscitation fluids. N Engl J Med. 2013 Sep 26;369(13):1243-51. doi: 10.1056/NEJMra1208627. No abstract available.
Clinical trial NCT03470272: Effects of Red Light LED Therapy on Body Contouring
Official title: Effects of Red Light LED Therapy on Body Contouring
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Obesity
Lead sponsor: Manamed Inc.
Sponsor class: INDUSTRY
First posted: 2018-03-19
Enrollment: 66
Sex: ALL
Minimum age (years): 18
Maximum age (years): 77
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Red light laser therapy using 635nm red light laser technology has previously been shown to cause lipolysis in subcutaneous fat as a non-surgical method to promote weight loss and body contouring. This study hypothesizes that red LED light therapy using 650nm red light LED (light emitting diode) technology produces similar results to the laser device (red LASER 635nm) when preformed using a specified treatment protocol.

Detailed description: Red light laser therapy using 635nm red light laser technology has previously been shown to cause lipolysis in subcutaneous fat as a non-surgical method to promote weight loss and body contouring. This study hypothesizes that red LED light therapy using 650nm red light LED (light emitting diode) technology produces similar results to the laser device (red LASER 635nm) when preformed using a specified treatment protocol.

Furthermore, it is hypothesized that the Vevazz therapy program achieves the results after one 28 minute treatment period. The predicate 635nm LED device (Photonica Professional by Ward Photonics) achieves its results after one 32 minute therapy program.

The FB Professional therapy program uses the FB Professional LED device for fat removal using LED red light therapy. This multi-site study reviews results from 70 randomly selected patients after a single treatment using the FB Professional LED device.

Eligibility criteria: Inclusion Criteria:

* At least 18 years or older.
* May be male or female.
* Generally good health.

Exclusion Criteria:

* Minors.
* Open wounds or sores.
* Pacemaker.
* Photosensitivity.
* Epilepsy.
* Any form of cancer.
* Severe kidney or liver problems.
* Thyroid problems.
* Pregnant or nursing.

Primary outcomes:
measure: Change in Fat Amount (Reduction) in Treatment Area as Measured in Inches Lost
timeFrame: One 28 minute session
Secondary outcomes:
Other outcomes:
Locations:
city: New Port Richey
country: United States
facility: Ligertwood Chiropractic
state: Florida
Study officials:
affiliation: Human Studies Group
name: Paul Ligertwood, Dr
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02466672: The Role and Effect of Anemia in Children With Pneumonia
Official title: The Role and Effect of Anemia in Children With Pneumonia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Anemia
Pneumonia
Lead sponsor: Massachusetts General Hospital
Sponsor class: OTHER
Collaborators: name: Mbarara University of Science and Technology
name: Thrasher Research Fund
name: National Institutes of Health (NIH)
name: National Heart, Lung, and Blood Institute (NHLBI)
First posted: 2015-06-09
Enrollment: 212
Sex: ALL
Minimum age (years): 6
Maximum age (years): 59
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Children age 6 months to 59 months admitted to the hospital with WHO-defined severe pneumonia

Brief summary: This study will measure the effect of anemia on the outcomes of hospitalized children with severe pneumonia.


Eligibility criteria: Inclusion Criteria:

* Age 6 months to 59 months
* WHO-defined severe pneumonia

Exclusion Criteria:

* Congenital heart disease

Primary outcomes:
measure: Time to recovery from pneumonia
timeFrame: participants will be followed for the duration of hospital stay, an expected average of 5 days
Secondary outcomes:
Other outcomes:
Locations:
city: Mbarara
country: Uganda
facility: Mbarara University of Science and Technology
Study officials:
affiliation: Massachusetts General Hospital
name: Peter P Moschovis, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03730272: Occurence of Pain and Use of Analgesic Treatment in Multi-trauma Patients of Intermediate Seveity
Official title: The Incidence and Strenght of Pain in Conscious Multitrauma Patients, 0-14 Days After Multitrauma
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Post Traumatic Pain
Post Traumatic Analgesic Treatment
Lead sponsor: Oslo University Hospital
Sponsor class: OTHER
First posted: 2018-11-05
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients With any kind of multitrauma, fullfilling inclusion/exclusion

Brief summary: To register the perceived pain score during 0-14 days after multitrauma in conscious patients and to register the use (type and dose) of analgesic treatment in the same period.


Eligibility criteria: Inclusion Criteria:

* Patient With trauma, ISS \> 8

Exclusion Criteria:

* Unconscious patients at admission
* patients due for major surgery within 3 hrs of admission
* patients primary admitted to other hospitals
* not able to communicate in Norewegian

Primary outcomes:
measure: Worst pain
timeFrame: 0-14 days
measure: Average pain
timeFrame: 0-14 days
Secondary outcomes:
measure: analgesic methods
timeFrame: 0-14 days
Other outcomes:
Locations:
city: Oslo
country: Norway
facility: Dept of Anesthesiology, Oslo University Hospital, Ullevaal
Study officials:
References:
Clinical trial NCT01253772: Pulse Oximeter Responses to Multiple Levels of Stable Hypoxia in Neonates
Official title: Pulse Oximeter Responses to Multiple Levels of Stable Hypoxia in Neonates
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hypoxia
Lead sponsor: SterilMed, Inc.
Sponsor class: INDUSTRY
First posted: 2010-12-03
Enrollment: 4
Sex: ALL
Maximum age (years): 6
Standard ages: CHILD
Accepts healthy volunteers: no
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Neonatal children undergoing complex cardiac surgical procedures.

Brief summary: Validate pulse oximeter sensors in neonates by comparing sensor readings to blood samples during cardiac surgery.

Detailed description: Researchers at the University of California, San Francisco have developed methods that permit them to test multiple pulse oximeter sensors on neonates simultaneously during cardiac surgery. During this type of surgery, the arterial oxygen saturation changes over a wide range, providing an ideal arena for the assessment of neonatal pulse oximeter sensors at many levels of oxygen saturation. Several arterial blood gas samples are typically obtained during these procedures. Saturation of each arterial blood sample is determined by direct oximetry in a hemoximeter and this measurement is compared to the reading displayed on the pulse oximeter.

Eligibility criteria: Inclusion Criteria:

* Neonatal patient scheduled to undergo cardiac surgery where routine blood draws would be taken
* Understand and provide signed parental/guardian consent

Exclusion Criteria:

* Failure to obtain parental consent
* Patients shown to have an adverse reaction to medical tape/adhesive

Primary outcomes:
measure: SpO2 Accuracy Verification Study (ARMS) of ≤ 3%
timeFrame: During Analysis - data were collected anywhere from the beginning of surgery until the completion of the procedure
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: University of California, San Francisco
name: Greg Stratmann, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06889272: Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery
Official title: Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Congenital Cardiac Defect
Acute Renal Injury
Blood Transfusion Complication
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2025-03-21
Enrollment: 205
Sex: ALL
Maximum age (years): 18
Standard ages: CHILD
ADULT
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Pediatric patients who applied to Hacettepe University Faculty of Medicine (HÜTF) Hospital and underwent cardiac surgery by the Department of Cardiovascular Surgery between January 1, 2013 and December 31, 2023 will be included in the study.

Brief summary: Blood transfusion strategies in cardiac surgery are a research topic that has been studied more for adults. There is not enough data on this subject for children in studies. Investigators aim to examine the renal damage risk level of blood transfusion volume, which is one of the modifiable risk factors that can cause acute kidney injury in pediatric cases undergoing cardiac surgery.

The main question it aims to answer is:

What is the effect of blood transfusion volume on the risk of renal damage in pediatric cardiovascular surgery? The names of the patients who were operated on by the Department of Cardiovascular Surgery will be accessed from the system records and their files will be reviewed. The patients' demographic information, anesthesia management and postoperative renal function tests will be scanned.


Eligibility criteria: Inclusion Criteria:

* pediatric patients undergoing cardiovascular surgery

Exclusion Criteria:

* Being over 18 years old Weighting over 30 kg Preoperative acute kidney injury

Primary outcomes:
measure: postoperative acute renal failure
timeFrame: From registration to the end of the second postoperative day
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University Anesthesiology and Reanimation
Study officials:
affiliation: Assistant professor
name: Murat Izgi
role: STUDY_DIRECTOR
References:
Clinical trial NCT05324072: Musculoskeletal Disorders Among Egyptian Anesthesiologists
Official title: Prevalence and Risk Factors of Work Related Musculoskeletal Disorders Among Egyptian Anesthesiologists: a Cross-sectional Study.
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Musculoskeletal Disorders
Lead sponsor: Sohag University
Sponsor class: OTHER
First posted: 2022-04-12
Enrollment: 150
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Egyptian anesthesiologists on practice inside or outside Egypt

Brief summary: This cross-sectional online survey questionnaire based study for Prevalence and risk factors of work related musculoskeletal disorders among Egyptian anesthesiologists.

Detailed description: This cross-sectional online survey questionnaire based study will be approved by medical ethical committee of Sohag faculty of medicine. Survey participants will be reassured that all data collected are for research purposes. Responses will be voluntary anonymous and have no identifying data. Egyptian anaesthesiologists will be invited through social media to participate in the survey.

Eligibility criteria: Inclusion Criteria:

* Egyptian anesthesiologists on clinical practice

Exclusion Criteria:

-

Primary outcomes:
measure: Prevalence of work related musculoskeletal disorders among Egyptian anesthesiologists
timeFrame: April to September 2022
Secondary outcomes:
measure: Risk factors of work related musculoskeletal disorders among Egyptian anesthesiologists
timeFrame: April to September 2022
Other outcomes:
Locations:
city: Aswan
country: Egypt
facility: Sohag faculty of medicine
state: Please Select
Study officials:
affiliation: Sohag Faculty of medicine
name: Bahaa Mohammed, MD
role: STUDY_DIRECTOR
References:
Clinical trial NCT03563872: Enhancing Systems of Care to Improve Hypertension Guideline Implementation
Official title: Enhancing Systems of Care to Improve Hypertension Guideline Implementation to Communities With Health Disparities
Study type: INTERVENTIONAL
Overall status: WITHDRAWN
Phase: NA
Conditions: Hypertension
Keywords: hypertension
team-based
guidelines
implementation
Lead sponsor: Henry Ford Health System
Sponsor class: OTHER
First posted: 2018-06-20
Enrollment: 0
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study is a prospective cluster randomized trial testing a systems-level strategy to implement current American Heart Association hypertension guidelines in African American communities at risk for cardiovascular related health disparities. The trial will take place within an integrated health system serving Detroit and will assess blood pressure control over one year's time.

Detailed description: The trial will randomize 12 clinics within the Henry Ford Health System to two arms. The first arm will be comparison clinics that continue to use existing team-based strategies for hypertension management. The second arm will be intervention clinics. These clinics will have enhancements to existing team-based hypertension management. The first enhancement is clinical decision support based in the electronic health record. The second enhancement is improved protocols to implement telehealth prescribing that is nurse-led.

The trial will enroll participants through an urban emergency department. Participants will be assigned to one of these 12 clinics and continue study activities for 1 year. Clinicians at the clinics will manage blood pressure. Study specific visits will occur at 3, 6, 9, and 12 months. Primary outcome assessment is 12 months.

Eligibility criteria: Inclusion Criteria:

* Adult (\>18 years) African Americans
* Lacks established primary care for BP management
* History of HTN
* SBP ≥ 140 mmHg

Exclusion Criteria:

* Pregnancy
* Need for hospitalization from ED
* Serious comorbid conditions
* Alcohol or drug dependence
* Suspected resistant HTN
* Anticipated poor-adherence to study designated primary care clinic

Primary outcomes:
measure: Change in systolic blood pressure
timeFrame: 12 months
Secondary outcomes:
measure: Therapeutic Intensity
timeFrame: 12 months
measure: Change in systolic blood pressure
timeFrame: 6 months
measure: Change in diastolic blood pressure
timeFrame: 12 months
measure: Treatment Congruence
timeFrame: 12 months
Other outcomes:
measure: Cost effectiveness
timeFrame: 12 months
Locations:
city: Detroit
country: United States
facility: Henry Ford Hospital
state: Michigan
Study officials:
References: