Clinical trial NCT04471493: Pediatric and Ambulatory Research in Infectious Diseases
Official title: Real Time Surveillance of Pediatric Infectious Diseases in French Ambulatory Care: PARI Study
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Otitis
Bronchiolitis
Influenza
Pharyngitis
Varicella
Pneumonia
Gastroenteritis
Keywords: Vaccination
Antibiotic treatment
Point of care test
automated data extraction
network
Lead sponsor: Association Clinique Thérapeutique Infantile du val de Marne
Sponsor class: OTHER
Collaborators: name: AFPA (Association Française de Pédiatrie Ambulatoire)
name: GlaxoSmithKline
name: Sanofi
name: Pfizer
name: Merck Sharp & Dohme LLC
First posted: 2020-07-15
Enrollment: 400000
Sex: ALL
Minimum age (years): 1
Maximum age (years): 16
Standard ages: CHILD
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Children under 16 years with infectious disease

Brief summary: Many ambulatory networks are mainly based on diagnoses made by first-line physicians not specifically trained to join the network. Here we aim to set up a surveillance network on pediatric infectious diseases with an investment in teaching with specific trainings of participating pediatricians, increasing in use of point of care tests, and automated data extraction from the computers of the pediatricians.

Detailed description: 107 pediatricians among the 1400 members of the French ambulatory pediatric association, AFPA (Association Française de Pédiatrie Ambulatoire) were involved in this survey.To belong to the PARI network, pediatricians have to use the same software, Axi5-Infansoft (developed by CompuGroup Medical, Nanterre, France) for electronic medical record of children. The pediatricians were trained to the use of point of care tests and to the infectious diagnoses (otitis, pharyngitis, varicella, bronchiolitis, influenza, pneumonia, etc..). The study population consisted of all children under 16 years of age from the patient population for which an infectious disease was diagnosed.

Eligibility criteria: Inclusion Criteria:

* Children under 16 years of age with at least one infectious disease among:
* pharyngitis
* otitis
* pneumonia
* influenza
* bronchiolitisz
* varicella
* gastroenteritis
* enterovirus disease
* bordetella pertussis disease
* using the same same software, Axi5-Infansoft (developed by CompuGroup Medical, Nanterre, France)

Exclusion Criteria:

* parental refusal

Primary outcomes:
measure: Evaluation of the number of infectious diseases
timeFrame: 5 years
Secondary outcomes:
measure: Evaluation of the use of point of care tests
timeFrame: 5 years
measure: Evaluation of the antibiotic treatments
timeFrame: 5 years
Other outcomes:
Locations:
city: Créteil
country: France
facility: AFPA
Study officials:
affiliation: Association Clinique et Thérapeutique Infantile du Val de Marne
name: Robert Cohen
role: STUDY_DIRECTOR
References:
citation: Cohen R, Bechet S, Gelbert N, Frandji B, Vie Le Sage F, Thiebault G, Kochert F, Cahn-Sellem F, Werner A, Ouldali N, Levy C. New Approach to the Surveillance of Pediatric Infectious Diseases From Ambulatory Pediatricians in the Digital Era. Pediatr Infect Dis J. 2021 Jul 1;40(7):674-680. doi: 10.1097/INF.0000000000003116.