Clinical trial NCT06225388: Effect of Wearing a Compression Sock During Running on Muscle Soreness in Distance Runners.
Official title: Effect of Wearing a Compression Sock During Running on Delayed Onset Muscle Soreness in Distance Runners: A Randomised, Double-blind, Sham-controlled, Crossover Trial.
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Muscle Soreness
Perceived Recovery
Perceived Exertion
Affective Response
Heart Rate
Keywords: runner
garments
pain
stocking
knee
sports
Lead sponsor: Centro Universitário Augusto Motta
Sponsor class: OTHER
First posted: 2024-01-25
Enrollment: 44
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: Running is the most popular physical activity worldwide. Although running provides many health benefits, it is often associated with injuries and symptoms such as delayed onset muscle soreness. There is still a paucity of interventions that can effectively minimise these symptoms in distance runners.

Detailed description: Our primary aim is to explore the effect of compression socks during running on delayed onset muscle soreness after running. Our secondary aims are to explore the effects of compression socks during running on perceived recovery, perceived exertion, affective response, and heart rate after running. This is a randomised, double-blind, sham-controlled crossover trial. Forty-four participants will be recruited via social media, running clubs and the running coaches' network of the research team. Participants will be randomised to complete a running protocol under two conditions (compression socks or sham socks). After that, there will be a wash-out period of 7 to 10 days, and participants will repeat the running protocol under the other conditions. Primary outcome: lower limb muscle soreness will be collected, using a 0-100 numerical pain scale, immediately, 24 hours and 48 hours after the running protocol, with 24 hours post-protocol being the primary timepoint. Secondary outcomes: perceived recovery will be collected, using a 0-10 scale immediately, 24 hours and 48 hours after the running protocol. Perceived exertion, affective response, and heart rate will be registered only immediately after the protocol. Between-group differences will be explored using linear mixed models.

Eligibility criteria: Inclusion Criteria:

* Run consistently in the last six months (at least three times a week and at least 10 kilometres per week);
* Runners who did not run further than 42 kilometres in the last month.

Exclusion Criteria:

* Pregnancy;
* Any lower limbs fracture in the last 12 months;
* History of lower limb arthroplasty or osteotomy, previous venous thrombosis, kidney disease;
* Any running-related injury in the last six months. A running-related injury will be considered the presence of lower limb pain that caused restriction, stoppage of running (distance, speed, duration, or training) for at least seven days or three consecutive scheduled training sessions or the need for a health professional treatment

Primary outcomes:
measure: Lower limb muscle soreness.
timeFrame: 24 hours post-intervention.
Secondary outcomes:
measure: Lower limb muscle soreness.
timeFrame: 5 minutes post-intervention, and 48 hours post-intervention.
measure: Perceived recovery.
timeFrame: 5 minutes post-intervention, 24 hours, and 48 hours post-intervention.
measure: Perceived exertion
timeFrame: 5 minutes post-intervention.
measure: Affective response
timeFrame: 5 minutes post-intervention.
measure: Heart rate
timeFrame: Through the intervention, an average of 30 minutes.
Other outcomes:
Locations:
city: Rio De Janeiro
country: Brazil
facility: Centro Universitário Augusto Motta
Study officials:
affiliation: Centro Universitário Augusto Motta
name: Leandro AC Nogueira, PhD
role: STUDY_CHAIR
References: