Clinical trial NCT06780878: Comparison of Progressive Muscle Relaxation and Stretching Exercises in Diabetic Population
Official title: Comparison of Progressive Muscle Relaxation and Stretching Exercises Mediated by Stress in Diabetic Population
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Diabetes Mellitus Type 2
Keywords: perceived stress
progressive muscle relaxation
stretching exercises
heart rate variability
cortisol levels
galvanic skin response
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2025-01-17
Enrollment: 36
Sex: FEMALE
Minimum age (years): 35
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The study consists of 2 active comparators and 1 control group.
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to compare the effects of Progressive muscle relaxation and stretching exercises mediated by stress on heart rate variability, cortisol level, galvanic skin response and perceived stress scale. The main questions it aims to answer are, Will there be a significant difference between the effects of Progressive muscle relaxation and stretching exercises in the diabetic population? Can stress mediate the effects of Progressive muscle relaxation and stretching exercises in the diabetic population?

Researchers will compare the effects of Progressive muscle relaxation and stretching exercises mediated by stress on heart rate variability, cortisol level, galvanic skin response and perceived stress scale.

Participants will:

Be given session of Progressive muscle relaxation or stretching exercises or no physical therapy treatment 3 sessions per week for 2 weeks and visit the clinic once every 3 days for 2 weeks for intervention. Measurements will be taken before and after every session. Perceived Stress will be assessed at the start of the intervention at baseline and then after 2 weeks.

Detailed description: The subject of this research is individuals with type 2 diabetes who also experience depression. Progressive muscle relaxation (PMR) has the potential to reduce blood sugar levels in type 2 diabetes patients. This reduction is linked to the stress, both physical and psychological, experienced by the patients.

When stressors are assessed, muscle tension is created, which signals the brain and creates a feedback. PMR works to interrupt this loop by stimulating the parasympathetic nervous system and influencing the hypothalamus through focused concentration, promoting a positive mindset and reducing stress on the hypothalamus. Stretching can also be easily integrated into a diabetic's daily routine promoting both physical and mental wellbeing.

Most studies focus on PMR or stretching exercises separately in managing stress, but comparing these two interventions in terms of stress reduction and physical outcomes in diabetics is limited.

Understanding which intervention provides better stress relief could lead to more targeted recommendations in diabetic care.

Eligibility criteria: Inclusion Criteria:

* Age 35-65 years Females Uncontrolled Diabetes Mellitus Sedentary Lifestyle Has never undergone progressive muscular relaxation before.

Exclusion Criteria:

* Unstable Angina Cardiac arrhythmia Postural deformities Left ventricular ejection fraction \< 45%

Primary outcomes:
measure: Heart rate variability
timeFrame: 24 hours
measure: Cortisol levels
timeFrame: 24 hours
measure: Galvanic skin response
timeFrame: 24 hours
measure: Perceived stress
timeFrame: 2 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Pakistan Railway General Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Maria Naeem, DPT, MS-CPPT
role: PRINCIPAL_INVESTIGATOR
References: