Clinical trial NCT06066489: Effect of Educational Program About Preventive Care Bundle for Prevention of Ventilator Associated Pneumonia Among Newborns
Official title: Effect of Educational Program for Nurses About Preventive Care Bundle for Prevention of Ventilator Associated Pneumonia Among Newborns
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Ventilator Associated Pneumonia
Keywords: newborn
Lead sponsor: Damanhour University
Sponsor class: OTHER
First posted: 2023-10-04
Enrollment: 137
Sex: ALL
Minimum age (years): 3
Maximum age (years): 30
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: SEQUENTIAL
Intervention model description: A prospective, quasi-experimental, pre- and post-study with a one month baseline period; one month intervention period and three months post-intervention period
Primary purpose: PREVENTION

Brief summary: This study is designed to investigate the effect of educational program for nurses about preventive care bundle for prevention of ventilator associated pneumonia among newborns.

Detailed description: Neonatal ventilator associated pneumonia (VAP) is a common nosocomial infection and a frequent reason for empirical antibiotic therapy in NICUs. Ventilator associated pneumonia (VAP) is defined as a nosocomial lower airway infection in intubated patients with onset after 48 h or more of invasive mechanical ventilation.Prevention of VAP has been primarily achieved by the "bundle approach"; this involves the simultaneous application of several preventive strategies for all patients.In Egypt and other developing countries, reports on the success of VAP intervention strategies, particularly among neonates, are scarce. So, it is important to conduct educational programs for nurses about VAP to decrease its incidence.

Eligibility criteria: Inclusion Criteria:

* Gestational age ≥34 weeks
* Intubated newborns and those expected to receive mechanical ventilation for more than 48 hours.

Exclusion Criteria:

* Newborns with diagnosis of pneumonia at the time of admission.
* Newborns developed pneumonia in the first 48 hours of mechanical ventilation.
* Newborns subjected to reintubation.
* Immunosuppressed newborns.

Primary outcomes:
measure: prevalence of VAP among newborns ( the number of newborns diagnosed with VAP during the study period
timeFrame: before intervention as baseline ( Day 1), immediately after the intervention, 3 months later after intervention
Secondary outcomes:
measure: nurses practices about prevention of ventilator associated pneumonia after implementing the training program will be compared by their practices before the intervention using Observational Checklist
timeFrame: before intervention as baseline(Day 1), immediately after the intervention, 3 months later after intervention
Other outcomes:
Locations:
Study officials:
References:
citation: Iosifidis E, Pitsava G, Roilides E. Ventilator-associated pneumonia in neonates and children: a systematic analysis of diagnostic methods and prevention. Future Microbiol. 2018 Sep;13:1431-1446. doi: 10.2217/fmb-2018-0108. Epub 2018 Sep 26.
citation: Alriyami A, Kiger JR, Hooven TA. Ventilator-Associated Pneumonia in the Neonatal Intensive Care Unit. Neoreviews. 2022 Jul 1;23(7):e448-e461. doi: 10.1542/neo.23-7-e448.
citation: Niedzwiecka T, Patton D, Walsh S, Moore Z, O'Connor T, Nugent L. What are the effects of care bundles on the incidence of ventilator-associated pneumonia in paediatric and neonatal intensive care units? A systematic review. J Spec Pediatr Nurs. 2019 Oct;24(4):e12264. doi: 10.1111/jspn.12264. Epub 2019 Jul 23.