Clinical trial NCT03800732: The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers
Official title: The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers: Randomized Cross-over Study.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Shift Work Type Circadian Rhythm Sleep Disorder
Lead sponsor: Federal University of Uberlandia
Sponsor class: OTHER
First posted: 2019-01-11
Enrollment: 10
Sex: MALE
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: This study aimed to verify the influence of night work and food intake during the night shift on the eating behavior of fixed night workers the next day.

Detailed description: Night work causes restriction of sleep time and circadian misalignment and, therefore, have been associated with nutritional and metabolic impairments. The objective of the present study is to verify the influence of night work and food intake in this period on the behavior of the following day. The workers selected by criteria and inclusion and exclusion will be evaluated at the baseline: anthropometric parameters, food consumption and perception, duration of food consumption, sleep habits and chronobiological pattern (sleep monitoring by actigraphy, chronotype, social jet lag), parameters biochemical (blood count, lipidogram, C-reactive protein, cortisol, glucose, insulin).Subsequently, 30 workers will integrate a randomized and controlled crossover clinical study with three randomly established interventions: (1) two nights of work without meals during the shift; (2) two nights of work with a meal during the shift; (3) two nights sleep. Participants will go to the laboratory the morning after the second night of each condition to offer a test meal ad libitum, which will consist of foods of various compositions and food groups. Preprandial metabolic assessments will be conducted (ghrelin, GLP-1 - glucagon-like peptide 1, PYY-peptide YY). The following postprandial evaluations will be carried out and in the 24 hours following the experiment: food choices (record of all foods) and food perceptions (hunger, appetite, satiety and eating). It is expected to determine how nocturnal versus nocturnal work, and nocturnal fasting versus nocturnal fasting affect the next day's food choices.

Eligibility criteria: Inclusion Criteria:

* Agree to participate in the study and sign the Informed Consent Form (EHIC).
* No significant changes in body mass in the last 6 months.
* With stable food and sleep routine in the last two months.

Exclusion Criteria:

* Failure to provide the information or material necessary for the development of the study.
* Report of chronic non-communicable diseases.
* Report of diagnosed and untreated psychiatric disorders.

Primary outcomes:
measure: Preprandial metabolic
timeFrame: 6 months
measure: Change of food perceptions
timeFrame: 6 months
Secondary outcomes:
measure: Food behavior
timeFrame: 6 months
Other outcomes:
Locations:
city: Uberlândia
country: Brazil
facility: Cibele Aparecida Crispim
state: Minas Gerais
Study officials:
References: