Clinical trial NCT05031728: Cognitive Processing Therapy for Syrian Patients With PTSD
Official title: Cognitive Processing Therapy for the Treatment of Post-Traumatic Stress Disorder in Syrian Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Posttraumatic Stress Disorder (PTSD)
Keywords: Cognitive Processing Therapy (CPT)
Posttraumatic stress disorder (PTSD)
Syrians
Lead sponsor: British University In Egypt
Sponsor class: OTHER
First posted: 2021-09-02
Enrollment: 94
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Patients will be interviewed by a clinician and asked to complete the Clinician-Administered PTSD Scale (CAPS-5), Beck Depression Inventory (BDI-II), Beck Anxiety Inventory (BAI). Assessments will be conducted at baseline, 3-, and 12-months post treatment.
Primary purpose: TREATMENT

Brief summary: Background: Studies among Syrian refugees showed high prevalence rates of PTSD. The objective of the present study was to investigate the effectiveness of Cognitive Processing Therapy (CPT) in treating patients with posttraumatic stress disorder (PTSD) using a clinical trial. Methods: Data will be obtained through interviewing patients seeking for PTSD treatment. Patients will be interviewed by a clinician and asked to complete the Clinician-Administered PTSD Scale (CAPS-5), Beck Depression Inventory (BDI-II), Beck Anxiety Inventory (BAI). Assessments will be conducted at baseline, 3-, and 12-months posttreatment. The primary outcomes will be the scores of CAPS, BDI-II, and BAI. Results: we predict that CPT will result in greater reductions in CAPS scores.

Detailed description: Although individuals with PTSD experience significant suffering, disability, and a challenging clinical course, there are still significant gaps in the evidence addressing effective treatment options. Therefore, in the current study CPT will determine the effectiveness in treating Syrian patients with PTSD. Current study significantly adds to the existing literature. It is a novel study in Egypt and adds to the literature.

Eligibility criteria: Inclusion Criteria Their nationalities are Syrians

* age older than 18 years and younger than 65,
* patients meeting current diagnostic criteria for PTSD as defined in DSM-5
* have a good knowledge of English-language (reading, writing, and comprehension) because all assessments and therapy materials were in English

Exclusion Criteria

* having mental retardation
* having schizophrenia (or any other psychotic disorders).

Primary outcomes:
measure: assessing change in CAPS-5 scores between three time points
timeFrame: baseline (pre-intervention), posttreatment (immediately after the intervention), 12-months after the intervention
Secondary outcomes:
measure: assessing change in Beck Depression Inventory (BDI-II) scores between three time points
timeFrame: baseline (pre-intervention), posttreatment (immediately after the intervention), 12-months after the intervention
measure: assessing change in Beck Anxiety Inventory (BAI) scores between three time points
timeFrame: baseline (pre-intervention), posttreatment (immediately after the intervention), 12-months after the intervention
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: The British university in Egypt
Study officials:
affiliation: The British University in Egypt
name: Amani S Elbarazi, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: