Clinical trial NCT05606744: Effects of Blood Flow Restriction During Eccentric Resistance Exercise
Official title: Effects of Blood Flow Restriction During Multiple-joint Eccentric Resistance Training on Muscle Morphology and Function of the Lower Body
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Blood Flow Restriction
Lead sponsor: Utah State University
Sponsor class: OTHER
First posted: 2022-11-07
Enrollment: 45
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Individuals will be randomly assigned to a BFR or non BFR exercise condition. The subjects will perform a single, 3-5 minute bout of eccentric exercise on the Eccentron device either with BFR (with restriction cuffs on the thigh per the procedures below) or without the BFR.
Primary purpose: OTHER

Brief summary: The purpose of this study is to compare the muscle strength and muscle soreness effects experienced following short term (acute) eccentric exercise with and without blood flow restriction (BFR) performed at low - moderate training intensities.


Eligibility criteria: Exclusion Criteria:

* lower body surgery or injury in the last 12 months
* have any neuromuscular disease
* height \>76 inches tall
* height \<54 inches tall
* eccentric strength greater than 725 pounds
* pregnant or plan to be pregnant in the duration of the protocol
* don't do resistance exercise at least once per week
* perform intense cardio or strength training \>4 days per week
* Present with any other significant comorbid conditions that would impair the ability to participate in the exercise-based testing

Inclusion criteria:

* 18 - 30 years old
* strength train lower body 1-3 times per week

Primary outcomes:
measure: visual analog scale (soreness)
timeFrame: Baseline (pretest)
measure: visual analog scale (soreness)
timeFrame: immediately post exercise
measure: visual analog scale (soreness)
timeFrame: 24 hours post exercise
measure: visual analog scale (soreness)
timeFrame: 48 hours post exercise
measure: visual analog scale (soreness)
timeFrame: 72 hours post exercise
measure: force algometer (soreness)
timeFrame: Baseline (pretest)
measure: force algometer (soreness)
timeFrame: immediately post exercise
measure: force algometer (soreness)
timeFrame: 24 hours post exercise
measure: force algometer (soreness)
timeFrame: 48 hours post exercise
measure: force algometer (soreness)
timeFrame: 72 hours post exercise
Secondary outcomes:
measure: Eccentric muscle strength
timeFrame: Baseline (pretest)
measure: Eccentric muscle strength
timeFrame: immediately post exercise
measure: Eccentric muscle strength
timeFrame: 24 hours post exercise
measure: Eccentric muscle strength
timeFrame: 48 hours post exercise
measure: Eccentric muscle strength
timeFrame: 72 hours post exercise
measure: Single-leg hop
timeFrame: Baseline (pretest)
measure: Single-leg hop
timeFrame: immediately post exercise
measure: Single-leg hop
timeFrame: 24 hours post exercise
measure: Single-leg hop
timeFrame: 48 hours post exercise
measure: Single-leg hop
timeFrame: 72 hours post exercise
Other outcomes:
Locations:
Study officials:
affiliation: Utah State University
name: Brennan Thompson, PhD
role: PRINCIPAL_INVESTIGATOR
References: