Clinical trial NCT06222528: Reducing Stigma and Increasing Treatment Seeking Intentions Among Adolescents
Official title: Brief Personalized Videos to Reduce Stigma and Increase Treatment-seeking Behavior Among Adolescents With Depression
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stigma, Social
Mental Health Disorder
Adolescent Behavior
Depression
Lead sponsor: New York State Psychiatric Institute
Sponsor class: OTHER
First posted: 2024-01-24
Enrollment: 1200
Sex: ALL
Minimum age (years): 14
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Depression is a leading cause of illness and disability in teenagers. Longer duration of untreated depression (DUD) is associated with greater severity, poorer outcome, and cognitive impairment. Stigma toward people with depression has been identified as a barrier to seeking help; therefore, reducing stigma toward young people at depressive risk could enhance their receptivity to seeking treatment. Social contact is a form of interpersonal contact with members of the stigmatized group and the most effective type of intervention for improvement in stigma-related knowledge and attitudes.

In a prior study, the investigators developed short video interventions to reduce stigma and increase treatment seeking among adolescents with depression. The videos feature adolescent protagonists varied by race/ethncitiy and gender (Black girl, Black boy, White girl, White boy, Hispanic girl, Hispanic boy, nonbinary or transgender adolescent) who will share their experiences with depression, challenges, and recovery process. The investigators would like to conduct a randomized controlled trial (RCT) to test the efficacy of these tailored videos as compared to a video control condition (which provides information about depression and how to seek help but does not include a personal story) on reducing self-stigma and increasing help-seeking intentions and behavior at baseline, post, 2 week follow-up, and 4 week follow-up among adolescents ages 14-18 recruited via Cloudresearch. The videos will be shown again at 2 week follow-up.

Detailed description: In a randomized control trial (RCT) with pre-, post-intervention, and 2 and 4 week follow-up assessments, the investigators aim to test the efficacy of brief social contact video interventions, varying protagonist race/ethnicity, as compared to video control in reducing depression related stigma and increasing treatment-seeking intentions and behavior among adolescents ages 14-18 recruited via Cloudresearch, a crowdsourcing platform. The control condition will include a video that will provide information about depression and how to seek help but does not include a personal story. The tailored video interventions will be assigned based on participant demographics and will include adolescent protagonists varied by race/ethnicity and gender (Black girl, Black boy, White girl, White boy, Hispanic girl, Hispanic boy, nonbinary or transgender adolescent). Videos will be shown at baseline and 2 week follow-up. The investigators hypothesize that 1) Brief social contact-based video interventions will reduce stigma towards depression and increase treatment-seeking intentions and behavior compared to video control which provides information about depression and help seeking but does not include a personal story.

Eligibility criteria: Inclusion Criteria:

* Ages 14-18
* English speaking
* US Residents

Exclusion Criteria:

* Age less than 14 or greater than 18
* Non-English speaking
* Non-US Resident

Primary outcomes:
measure: Depression Stigma
timeFrame: Baseline
measure: Depression Stigma
timeFrame: Post (immediately after the videos are shown)
measure: Depression Stigma
timeFrame: 2 week follow-up
measure: Depression Stigma
timeFrame: 4 week follow-up
measure: Attitude Towards Seeking Professional Psychological Help
timeFrame: Baseline
measure: Attitude Towards Seeking Professional Psychological Help
timeFrame: Post (immediately after the videos are shown)
measure: Attitude Towards Seeking Professional Psychological Help
timeFrame: 2 week follow-up
measure: Attitude Towards Seeking Professional Psychological Help
timeFrame: 4 week follow-up
Secondary outcomes:
measure: Emotional engagement
timeFrame: Post (immediately after the videos are shown
measure: Emotional engagement
timeFrame: 2 week follow-up
measure: Treatment related stigma
timeFrame: Baseline
measure: Treatment related stigma
timeFrame: Post (immediately after the videos are shown)
measure: Treatment related stigma
timeFrame: 2 week follow-up
measure: Treatment related stigma
timeFrame: 4 week follow-up
measure: Barriers to Access to Care Evaluation (BACE V3)
timeFrame: Baseline
measure: Barriers to Access to Care Evaluation (BACE V3)
timeFrame: Post (immediately after the videos are shown)
measure: Barriers to Access to Care Evaluation (BACE V3)
timeFrame: 2 week follow-up
measure: Barriers to Access to Care Evaluation (BACE V3)
timeFrame: 4 week follow-up
measure: Mental Health Treatment
timeFrame: Baseline
measure: Actual help seeking
timeFrame: 2 week follow-up
measure: Actual help seeking
timeFrame: 4 week follow-up
Other outcomes:
Locations:
city: New York
country: United States
facility: New York State Psychiatric Institute
state: New York
Study officials:
References:
citation: Griffiths KM, Christensen H, Jorm AF, Evans K, Groves C. Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomised controlled trial. Br J Psychiatry. 2004 Oct;185:342-9. doi: 10.1192/bjp.185.4.342.
citation: Elhai JD, Schweinle W, Anderson SM. Reliability and validity of the Attitudes Toward Seeking Professional Psychological Help Scale-Short Form. Psychiatry Res. 2008 Jun 30;159(3):320-9. doi: 10.1016/j.psychres.2007.04.020. Epub 2008 Apr 22.
citation: de Vreede T, Andel SA, de Vreede GJ, Spector P, Singh V, Padmanabhan B. What is engagement and how do we measure it? Toward a domain independent definition and scale. Proceedings of the 52nd Hawaii International Conference on System Sciences. 2019, Hawaii. p. 749-758.
citation: Clement S, Brohan E, Jeffery D, Henderson C, Hatch SL, Thornicroft G. Development and psychometric properties the Barriers to Access to Care Evaluation scale (BACE) related to people with mental ill health. BMC Psychiatry. 2012 Jun 20;12:36. doi: 10.1186/1471-244X-12-36.
citation: Brenner RE, Colvin KF, Hammer JH, Vogel DL. Using Item Response Theory to Develop Revised (SSOSH-7) and Ultra-Brief (SSOSH-3) Self-Stigma of Seeking Help Scales. Assessment. 2021 Jul;28(5):1488-1499. doi: 10.1177/1073191120958496. Epub 2020 Sep 25.