Clinical trial NCT06221878: Comparison of Laparoscopic and Open Surgery for Colorectal Malignancy in Obese Patients
Official title: Analysis of the Prognostic Impact of Laparoscopic Surgery in Patients With Systemic Obesity and Colorectal Malignant Tumors
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Colorectal Cancer
Obesity
Keywords: Colorectal cancer
obesity
laparoscopy surgery
open surgery
postoperative survival analysis
Lead sponsor: Chang Gung Memorial Hospital
Sponsor class: OTHER
First posted: 2024-01-24
Enrollment: 473
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Stage I \~ III Colorectal adenocarcinoma patients with BMI ≥ 30 kg/m2 who underwent colorectal surgery at the Linkou branch of the Chang Gung Memorial Hospital (CGMH) between January 2009 and December 2019.

Brief summary: The goal of this observational study is to compare laparoscopic and open surgery outcomes in colorectal cancer patients with BMI ≥ 30 kg/m2 . The main question\[s\] it aims to answer are:

1. the short-term outcome and postoperative outcomes of patients treated with open group versus laparoscopy group
2. the long-term oncologic outcome of patients treated with open group versus laparoscopy group

This study is a retrospective and observational study. Subjects were not be given or offered any treatment during the study. The investigator reviewed the patient's medical history and examination report to determine eligibility based on inclusion and exclusion criteria.

If there is a comparison group: Researchers compared the open group and laparoscopy group to see if the laparoscopic group have better short-term outcomes with comparable oncologic outcomes to the open group.

Detailed description: This study is a retrospective and observational study. Subjects were not be given or offered any treatment during the study. The investigator reviewed the patient's medical history and examination report to determine eligibility based on inclusion and exclusion criteria.

Given the uncertainty regarding the long-term outcomes of laparoscopy in obese patients with CRC, this study aimed to analyse a decade of data comparing laparoscopic and open surgery outcomes in patients with BMI ≥ 30 kg/m2 who had undergone treatment for CRC at the Linkou Chang Gung Hospital.

Eligibility criteria: Inclusion Criteria:

* CRC patients with BMI ≥ 30 kg/m2 who underwent colorectal surgery at the Linkou branch of the Chang Gung Memorial Hospital (CGMH) between January 2009 and December 2019.

Exclusion Criteria:

* non-adenocarcinoma neoplasms
* Stage IV CRC

Primary outcomes:
measure: Short-term outcome
timeFrame: 2009 to 2019
measure: Short-term outcome
timeFrame: 2009 to 2019
measure: Short-term outcome
timeFrame: 2009 to 2019
measure: Short-term outcome
timeFrame: 2009 to 2019
measure: Short-term outcome
timeFrame: 2009 to 2019
Secondary outcomes:
measure: Long-term Oncologic outcome
timeFrame: 2009 to 2019
measure: Long-term Oncologic outcome
timeFrame: 2009 to 2019
measure: Long-term Oncologic outcome
timeFrame: 2009 to 2019
Other outcomes:
Locations:
Study officials:
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