Clinical trial NCT02354729: Encouraging Allergic Young Adults to Carry Epinephrine
Official title: Using Text Messaging and Financial Incentives to Encourage Allergic Young Adults to Carry Epinephrine
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Adherence
Food Allergy
Lead sponsor: University of Pennsylvania
Sponsor class: OTHER
First posted: 2015-02-03
Enrollment: 33
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Fifteen million Americans suffer from food allergies. Food allergies can be life threatening; the only known life-saving treatment is epinephrine. Adolescents/young adults are at increased risk of adverse events, because of increased risk-taking with food and decreased likelihood of carrying epinephrine. This is a pilot randomized trial to test text message reminders, with and without financial incentives, to encourage allergic young adults to carry epinephrine.

Detailed description: Aim: We pilot tested a novel strategy to encourage young adults with food allergies to carry their epinephrine auto-injectors. Adolescents/young adults are at increased risk of adverse events, because of increased risk-taking with food and decreased likelihood of carrying epinephrine.

Study design: This is a pilot randomized controlled trial, with a survey component. Text messaging is the mode of communication and inquiry with study participants.

Hypothesis: The intervention group, which will receive modest financial incentives for carrying epinephrine, will be more likely to demonstrate that they are carrying their epinephrine, when queried by the study team.

This study employs text messaging, along with photography, as a mode of momentary ecologic assessment, or real-time measurement of epinephrine carrying. In addition, text messaging was used as a mode of asking questions regarding food allergy knowledge and beliefs among young adults. Text messages were sent from a designated telephone (and telephone number) purchased for use in this study. We used text messaging for reminder messages, text responses, and for the participants to send photographs back to us. We converted text message data (participants responses) into a RedCap database. Our research coordinator sent and received the text messages and compiled a secure RedCap database of responses.

Eligibility criteria: Inclusion Criteria:

* Have known food allergy
* Epinephrine auto-injector prescription
* Access to a cell phone with ability to send picture messages

Exclusion Criteria:

-

Primary outcomes:
measure: Proportion of check-ins at which participant is carrying epinephrine
timeFrame: 10 randomly timed check-ins during the 7 week intervention period
Secondary outcomes:
measure: Self-reported acceptability of text messages
timeFrame: Measured at the end of the 7 week intervention
Other outcomes:
Locations:
Study officials:
affiliation: University of Pennsylvania
name: Carolyn C Cannuscio, ScD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Cannuscio CC, Dupuis R, Graves A, Seymour JW, Kounaves S, Strupp E, Leri D, Frasso R, Grande D, Meisel ZF. A behavioral economics intervention to encourage epinephrine-carrying among food-allergic adults: a randomized controlled trial. Ann Allergy Asthma Immunol. 2015 Sep;115(3):234-240.e1. doi: 10.1016/j.anai.2015.05.018. Epub 2015 Jun 17.