Clinical trial NCT05164289: Interest of EMDR Schizophrenic Disorders
Official title: Interest of EMDR (Eye Movement Desensitization and Reprocessing) Psychotherapy in the Management of Schizophrenic Disorders
Study type: OBSERVATIONAL
Overall status: TERMINATED
Conditions: Schizophrenic Disorders
Keywords: Schizophrenic disorders
Psychosis
Eye Movement Desensitization and Reprocessing
Lead sponsor: Hôpital NOVO
Sponsor class: OTHER
First posted: 2021-12-20
Enrollment: 6
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients hospitalized for decompensated psychotic disorder in the psychiatric departments of the Centers Hospitaliers of Pontoise or Villejuif.

Brief summary: The purpose of this study is to determine the interest of the use of EMDR (Eye Movement Desensitization and Reprocessing) psychotherapy in the management of psychotic disorders, in particular schizophrenic disorders.

Detailed description: Since 2015 more and more studies conducted by researchers, especially Dutch and English, are interested in the use of EMDR (Eye Movement Desensitization and Reprocessing) for other pathologies such as bipolar disorder, unipolar depression, anxiety disorders, psychotic disorders, substance use disorders and chronic pain.

These studies show that EMDR appears to be a technique that is both effective, capable of significantly improving symptoms, and without risk for patients, while respecting the protocol and the clinical stabilization provided during the procedure.

To date, the use of EMDR for the management of psychotic patients has not been the subject of any prospective study in France and the authors' conclusions converge on the fact that it is essential to carry out more research on the subject.

For this, the investigators wish to evaluate the effect of EMDR on the management of patients with schizophrenic disorders, on the basis that this psychotherapy would improve their quality of life (improvement of all the specific scores used in psychiatry). : PANSS, DES, HAD and WEMWBS scales).

Finally, the investigators believe that it is relevant to assess the benefit of EMDR six months after hospitalization of patients, in order to measure the maintenance of this efficacy in the medium term

Eligibility criteria: Inclusion Criteria:

* ≥ 18 years and over,
* Hospitalized for decompensated psychotic disorder, Positive diagnosis of schizophrenia or schizoaffective disorder (according to the DSM-V psychiatry manual),
* With positive or negative symptoms according to the Positive and Negative Syndrome Scale (PANSS),
* Stabilized clinical condition (considered compatible with hospital discharge),
* With ambulatory follow-up planned after hospitalization

Exclusion Criteria:

* \< 18 years,
* Patients who do not meet the diagnostic criteria (according to the DSM-V psychiatry manual) for schizophrenic or schizoaffective disorder),
* Non-French speaking or illiterate patients,
* Cognitive disorders making it impossible the understanding and the none- opposition to the study,
* Non-stabilized clinical condition (incompatible with hospital discharge),

Primary outcomes:
measure: Assessment of the decrease in the severity of positive or negative symptoms of schizophrenia
timeFrame: At 6 month after Hospital discharge (M0)
Secondary outcomes:
measure: Assessment of the decrease in the intensity of dissociative symptoms.
timeFrame: At 6 month after Hospital discharge (M0)
measure: Assessment of the decrease in the intensity of anxiety and depressive symptoms.
timeFrame: At 6 month after Hospital discharge (M0)
measure: Quality of life assessment
timeFrame: At 6 month after Hospital discharge (M0)
Other outcomes:
Locations:
city: Pontoise
country: France
facility: Departement of Psychiatry - Hospital René Dubos
city: Villejuif
country: France
facility: Departement of Psychiatry -Hospital Paul Guiraud
Study officials:
affiliation: Hospital René Dubos - Pontoise
name: Dr Marie-Claire ASMAR
role: PRINCIPAL_INVESTIGATOR
References: