Clinical trial NCT01987037: Neuropsychomotor Functions in Children With Autism Spectrum Disorder
Official title: Neuropsychomotor Functions in Children With Autism Spectrum Disorder
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Autism Spectrum Disorder
Keywords: autism spectrum disorder
neuropsychomotor assessment
NP-MOT
motor skills
gross motor
Lead sponsor: Centre Hospitalier Esquirol
Sponsor class: OTHER
First posted: 2013-11-19
Enrollment: 40
Sex: ALL
Minimum age (years): 4
Maximum age (years): 11
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: children attended in the Centre Hospitalier Esquirol and the CRA (Autism Reference Center) in Limousin, France, for suspiscion of autism

Brief summary: The aim of the study is to describe the feasibility of the passation of the assessment battery of psychomotor functions tests (NP-MOT) in children aged 4 to 11 years with a diagnosis of autism spectrum disorder: number and type of evaluable events, number and type of tests with a deficit compared to the standard results.

Detailed description: After informed consent obtention, the children will be submitted to the different tests of the battery to evaluate the psychomotor functions. The results will be compared with other data collected from the routine practise : socio-demographic data, medical and developmental antecedents,psychological tests (KABC II, Rey test, London Tower test, ...), psychomotor evaluation (MABC, evaluation of manual praxis, visual abilities, Frostig test), understanding data (N-EEL test), neuropediatric examination, clinical assessment (ADI-R, CARS).

The use of this battery allows this fine discriminative assessment of the psychomotor functions involved in the movement. Exploring each function will allow to take into account qualitative and quantitative aspects of the movement in every aspects, and this is not applied in the routine care until now. Calibration for each event can explore each function independently of each other, and will provide information to determine any specific developmental characteristics improve care.

Eligibility criteria: Inclusion Criteria:

* informed consent from the parents or the legal representative
* age 4 to 11
* autism spectrum disorder diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders, fourth edition- text revised

Exclusion Criteria:

* bad understanding of the french language
* motor disability from lesion or accidental origin, proved genetic or neurologic disease
* deafness, blindness
* parents with administrative or judiciary protection, and without health insurance

Primary outcomes:
measure: results to the NP-MOT tests battery
timeFrame: one day
Secondary outcomes:
Other outcomes:
Locations:
city: Limoges
country: France
facility: Centre de Ressources Autisme Limousin
city: Limoges
country: France
facility: Centre Hospitalier esquirol
Study officials:
References:
citation: Lasserre E, Vaivre-Douret L, Abadie V. Psychomotor and cognitive impairments of children with CHARGE syndrome: common and variable features. Child Neuropsychol. 2013 Sep;19(5):449-65. doi: 10.1080/09297049.2012.690372. Epub 2012 Jun 14.