Clinical trial NCT06308289: Combined Effects of Global Posture Re-education and Active Cycle of Breathing Technique in COPD
Official title: Combined Effects of Global Posture Re-education and Active Cycle of Breathing Technique on Cardiorespiratory Fitness, Posture and Quality of Life in Chronic Obstructive Pulmonary Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: chronic obstructive Pulmonary disease
Posture
Work of breathing
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-03-13
Enrollment: 68
Sex: ALL
Minimum age (years): 40
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized controlled trial
Primary purpose: TREATMENT

Brief summary: The randomized controlled trial will involve 30 participants, with Group A receiving GPRM and ACBT, while Group B follows the conventional COPD model that includes ACBT only.Assessments of heart rate, physical fitness, and quality of life will contribute to a nuanced understanding of joint function, informing future COPD treatment paradigms.

Detailed description: The focus of this study will be on addressing the critical challenge of treating chronic obstructive pulmonary disease (COPD), a globally prevalent and heterogeneous lung condition associated with substantial morbidity and mortality. With COPD anticipated to become the leading global cause of death, this research will investigate a novel intervention that combines global postural retraining (GPRM) and physical fitness, utilizing respiratory cycle technology (ACBT). This study assumes to enhance heart rate, posture, and overall quality of life in individuals with COPD. The randomized controlled trial will involve 30 participants, with Group A receiving GPRM and ACBT, while Group B follows the conventional COPD model that includes ACBT only. The study, utilizing nonprobability purposive sampling, will span six months to comprehensively evaluate cardiovascular, respiratory, and quality-of-life outcomes. Exclusion criteria ensure a representative sample, excluding individuals with severe diseases or recent surgeries. The significance of this investigation lies in its potential to revolutionize COPD treatment, offering a cost-effective approach that simultaneously enhances patient health. By targeting both biomechanical and respiratory aspects, the study aims to provide valuable insights into improving COPD treatment strategies globally, with a focus on the combined effects of global postural retraining and active breathing techniques. Assessments of heart rate, physical fitness, and quality of life will contribute to a nuanced understanding of joint function, informing future COPD treatment paradigms.

Eligibility criteria: Inclusion Criteria:

1. Adults aged 40-75 years diagnosed with stable COPD (according to GOLD guidelines).
2. Patients of both genders
3. FEV1: FVC ranging from 68 - 69%.
4. Predicted FEV1 of less than 70%.
5. Willingness to participate

Exclusion Criteria:

1. Acute Exacerbation of COPD
2. Participants with severe comorbidities, such as unstable cardiovascular diseases (e.g., recent myocardial infarction, uncontrolled hypertension)
3. Participants diagnosed with respiratory conditions other than COPD (such as asthma, interstitial lung disease)
4. Individuals who have undergone major thoracic or abdominal surgery within the past three months
5. Individuals with severe mental health conditions (such as uncontrolled psychosis or severe depression)
6. Pregnant or lactating individuals.

Primary outcomes:
measure: SF- 36 Questionnaire
timeFrame: 12 Weeks
measure: FEV1/FVC ratio
timeFrame: 12 Weeks
measure: 6-minute walk test
timeFrame: 12 Weeks
measure: Photogrammetry
timeFrame: 12 Weeks
measure: Forced expiratory volume (FEV1)
timeFrame: 12 Weeks
measure: Forced vital capacity (FVC)
timeFrame: 12 Weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Gujranwala
country: Pakistan
facility: Social Security Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Muhammad Faizan Hamid, MS-CPPT
role: PRINCIPAL_INVESTIGATOR
References: