Clinical trial NCT03241056: Cognitive Checking Intervention for Maladaptive Beliefs About Memory
Official title: Increasing Memory Confidence: a Novel Intervention for Obsessive-Compulsive Disorder
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Obsessive-Compulsive Disorder
Lead sponsor: University of Manitoba
Sponsor class: OTHER
First posted: 2017-08-07
Enrollment: 23
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A small (N = 24) pilot study developed a new and brief cognitive-behavioural therapy (CBT) module for checking symptoms (CBT-C) in obsessive-compulsive disorder (OCD). CBT-C targets maladaptive beliefs about memory and results show that it is effective at significantly decreasing checking symptoms as compared to a waitlist control. The objectives of the current investigation are to further investigate CBT-C by (1) replicating the pilot results in a larger sample; (2) using an active control condition (treatment as usual) as the comparison condition (3) including a 6-month follow-up, and (4) determining whether the association between maladaptive beliefs about memory at pre-treatment assessment are related to degree of checking symptom reduction following CBT-C. The findings of the study will have theoretical significance in adding to our understanding of the maladaptive belief domains relevant to the development and maintenance of OCD and supporting the cognitive model of compulsive checking. The relevant clinical significance is the further development of an intervention that could improve outcomes in treatment of persons with OCD. The key practical outcome of the research would be to add a stepped care offering to patients with OCD.


Eligibility criteria: Inclusion Criteria:

* Adult over the age of 18 living in the province of Manitoba, Canada.
* Diagnosis of OCD with clinically significant levels of compulsive checking (i.e., able to meet the diagnostic criteria for OCD according to the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition based solely on checking symptoms. Other OCD symptoms may be present and checking does not need to be the primary symptom.)

Exclusion Criteria:

* Active psychosis
* Active Mania
* Presence of a substance use disorder that would interfere with participation in the treatment

Primary outcomes:
measure: Vancouver Obsessional Compulsive Inventory - checking subscale (change)
timeFrame: Change in checking symptoms from pre-treatment to post-treatment at 3 weeks later
measure: Average time spent checking per week (change)
timeFrame: Change in average time spent checking from pre-treatment to post-treatment at 3 weeks later
measure: Vancouver Obsessional Compulsive Inventory - checking subscale
timeFrame: Avarege time spent checking at 6-month follow-up
Secondary outcomes:
measure: Beliefs about Memory Inventory (change)
timeFrame: Change in beliefs about memory from pre-treatment to post-treatment at 3 weeks later
measure: Beliefs about Memory Inventory
timeFrame: Beliefs about memory at 6 month follow-up
measure: Obsessive Beliefs Questionnaire (change)
timeFrame: Change in obsessive beliefs from pre-treatment to post-treatment at 3 weeks later
measure: Obsessive Beliefs Questionnaire
timeFrame: Obsessive beliefs at 6-month follow-up
Other outcomes:
Locations:
city: Winnipeg
country: Canada
facility: St. Boniface Hospital
state: Manitoba
Study officials:
References: