Clinical trial NCT04934709: Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance
Official title: Immediate Effects of Photobiomodulation Therapy Combined With Static Magnetic Field on the Subsequent Performance: a Randomized Crossover Triple-blinded Placebo-controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Skeletal Muscle Performance
Keywords: Photobiomodulation Therapy
Static Magnetic Field
Subsequent performance
Lead sponsor: University of Nove de Julho
Sponsor class: OTHER
First posted: 2021-06-22
Enrollment: 12
Sex: MALE
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: PREVENTION

Brief summary: There is evidence about the effects of photobiomodulation therapy (PBMT) alone and combined with static magnetic field (PBMT-sMF) on skeletal muscle fatigue, physical performance and post-exercise recovery in different types of exercise protocols and sports activity. However, it is unknown the effects of PBMT-sMF to improve the subsequent performance after a first set of exercise. Therefore, the aim of this study was to investigate the effects of PBMT-sMF, applied between two sets of exercises, on the subsequent physical performance.

Detailed description: A randomized, crossover, triple-blinded (assessors, therapist and volunteers), placebo-controlled trial was carried out. Healthy non-athletes' male volunteers were randomized and treated with a single application of PBMT-sMF and placebo between two sets of an exercise protocol performed on isokinetic dynamometer.

The order of interventions was randomized.

The primary outcome was fatigue index, measured by isokinetic dynamometer during the exercise protocol. The secondary outcomes were total work and peak torque measured by isokinetic dynamometer during the exercise protocol; and blood lactate, measured by blood samples collected before, 3 minutes after the first set of the exercise protocol, 3 minutes after the application of the intervention and 3 minutes after the second set of the exercise protocol.

Statistical analysis:

The findings were tested for normality using the Kolmogorov-Smirnov test and were determined to have a normal distribution. Data were expressed as the mean and standard deviation, and a two-way repeated measures ANOVA was performed to test between-group differences at each timepoint (treatment effects), mean difference (MD) and 95% confidence intervals (CI), followed by the Bonferroni post hoc test. The significance level was set at p \< 0.05.

Eligibility criteria: Inclusion criteria:

* Male healthy volunteers;
* Non-athletes or those who practiced physical activity up to once a week;
* Aged 18-35 years.

Exclusion criteria

* History of musculoskeletal injuries in the hip and knee regions in the two months prior to the study;
* Use of pharmacological agents and nutritional supplements;
* Chronic joint disease in the non-dominant lower limb.

Primary outcomes:
measure: Fatigue index
timeFrame: 1 minute after the end of exercise protocol.
Secondary outcomes:
measure: Total work
timeFrame: 1 minute after the end of exercise protocol.
measure: Peak torque
timeFrame: 1 minute after the end of exercise protocol.
measure: Blood lactate
timeFrame: 3 minutes after the first set of the exercise protocol, 3 minutes after the application of the intervention and 3 minutes after the second set of the exercise protocol.
Other outcomes:
Locations:
city: São Paulo
country: Brazil
facility: Laboratory of Phototherapy and Innovative Technologies in Health
Study officials:
References: