Clinical trial NCT06676878: Body Composition, Fitness, and Thermoregulation in Young Boys With Type I Diabetes vs. Healthy Soccer Players
Official title: Assessment of Differences in Body Composition, Physical Fitness, and Thermoregulatory Response to Incremental Exercise in Young Boys With Type I Diabetes and Healthy Soccer Players
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Diabetes
Keywords: diabetes
football
exercise
thermography
Lead sponsor: Poznan University of Physical Education
Sponsor class: OTHER
First posted: 2024-11-06
Enrollment: 40
Sex: MALE
Minimum age (years): 15
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: DIAGNOSTIC

Brief summary: The study aims to assess differences in body composition, exercise capacity, and thermoregulation between young soccer players with type 1 diabetes and their healthy peers. Real-time glycemic monitoring during exercise will provide insights for developing effective diabetes management strategies, enhancing athletes' health and performance.

Detailed description: The aim of the study is to assess differences in body composition, exercise capacity, and exercise-induced thermoregulation between young athletes (soccer players) with type 1 diabetes and their healthy peers (also soccer players). Specifically, the study seeks to understand how type 1 diabetes, periodic glycemic fluctuations, and the body's metabolic balance status impact these parameters. By monitoring glycemic levels in real-time during exercise, the research will provide valuable insights into the necessity and frequency of glycemic control for individuals engaging in physical activity of varying intensities. The data obtained from this study may be crucial for developing effective strategies for managing type 1 diabetes in athletes, ultimately contributing to the improvement of their overall health and physical performance. Additionally, these findings could inform guidelines and recommendations for safe and effective exercise practices for diabetic athletes.

Eligibility criteria: Inclusion Criteria:

* Active soccer training for at least 5 years

Exclusion Criteria:

* Comorbidities significantly affecting metabolism and thermoregulation

Primary outcomes:
measure: Skin temperature changes
timeFrame: during the test
Secondary outcomes:
measure: Glycemic monitoring
timeFrame: during the test
Other outcomes:
measure: Antropometric measurement - weight
timeFrame: before test
measure: Antropometric measurement - height
timeFrame: before test
measure: Bone Mineral Density (BMD):
timeFrame: before test
measure: Fat Mass
timeFrame: before test
measure: Lean Mass
timeFrame: before test
measure: Ventilation
timeFrame: during test
measure: Oxygen Consumption (VO2)
timeFrame: during the test
measure: Measurement Cardiovascular Parameters
timeFrame: during the test
measure: Monitoring Fatigue Levels Using the RPE Scale
timeFrame: during the test
measure: Lactate
timeFrame: during the test
measure: Glucose Levels from a Fingertip Blood Drop
timeFrame: during the test
Locations:
city: Poznan
country: Poland
facility: Human Movement Analysis Laboratory LaBthletics Academy of Physical Education in Poznań
state: Wlkp
Study officials:
affiliation: Department of Physical Therapy and Sports Recover, Poznan University of Physical Education
name: Anna Straburzynska-Lupa, Prof
role: STUDY_DIRECTOR
References:
citation: Wierzbicka E, Swiercz A, Pludowski P, Jaworski M, Szalecki M. Skeletal Status, Body Composition, and Glycaemic Control in Adolescents with Type 1 Diabetes Mellitus. J Diabetes Res. 2018 Sep 3;2018:8121634. doi: 10.1155/2018/8121634. eCollection 2018.
citation: Mysliwiec A, Skalska M, Michalak A, Chrzanowski J, Szmigiero-Kawko M, Lejk A, Jastrzebska J, Radziminski L, Lopez-Sanchez GF, Gawrecki A, Jastrzebski Z. Responses to Low- and High-Intensity Exercise in Adolescents with Type 1 Diabetes in Relation to Their Level of VO2 Max. Int J Environ Res Public Health. 2021 Jan 15;18(2):692. doi: 10.3390/ijerph18020692.
citation: De Ridder F, Ledeganck KJ, De Winter B, Braspenning R, Delbeke D, Renard E, Pozzilli P, Pieralice S, Vissers D, De Block C. Trends of glucose, lactate and ketones during anaerobic and aerobic exercise in subjects with type 1 diabetes: The ACTION-1 study. Diabetes Metab Res Rev. 2022 Sep;38(6):e3537. doi: 10.1002/dmrr.3537. Epub 2022 May 21.
citation: Reddy R, Wittenberg A, Castle JR, El Youssef J, Winters-Stone K, Gillingham M, Jacobs PG. Effect of Aerobic and Resistance Exercise on Glycemic Control in Adults With Type 1 Diabetes. Can J Diabetes. 2019 Aug;43(6):406-414.e1. doi: 10.1016/j.jcjd.2018.08.193. Epub 2018 Aug 30.
citation: McGinn R, Carter MR, Barrera-Ramirez J, Sigal RJ, Flouris AD, Kenny GP. Does type 1 diabetes alter post-exercise thermoregulatory and cardiovascular function in young adults? Scand J Med Sci Sports. 2015 Oct;25(5):e504-14. doi: 10.1111/sms.12344. Epub 2014 Dec 8.