Clinical trial NCT05905107: Neurodynamic Sequencing in Patients With Carpal Tunnel Syndrome
Official title: Effects of Neurodynamic Sequencing on Pain, Wrist Range of Movement and Functional Disability in Patients With Carpal Tunnel Syndrome
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Carpal Tunnel Syndrome
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-06-15
Enrollment: 56
Sex: ALL
Minimum age (years): 25
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Carpal tunnel syndrome is a compressive neuropathy of median nerve in the fascial tunnel at wrist which causes pain, numbness ,and tingling in the extremities. Common treatment options used in the treatment of carpal tunnel syndrome are conservative and surgical treatment option is better, this question is still a topic requiring more and more clinical trials. Neuromobilisation described by Butler is one of the treatment options which are used in the treatment of carpal tunnel syndrome in conjunction with other conservative measures.

This proposed study will find out the effectiveness of Neuromobilisation in treatment of carpal tunnel syndrome. As there is very little evidence available which Neuromobilisation technique is effective and what are the types of patients which can get benefit from this technique. This study will find out the effect of Neuromobilisation in patients suffering from carpal tunnel syndrome of non traumatic origin. This is a randomized clinical trial. Target population is patients suffering from carpal tunnel syndrome of non-traumatic origin. Data will be collected from District Headquarter Hospital Faisalabad. This study will include 56 participants according to the selection criteria. The participants will be randomly divided into two groups through sealed opaque envelop method.

Group A will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing proximal to distal in 3 sets of 15 repetitions in one session on alternate days for 4 weeks. Group B will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing distal to proximal in 3 sets of 10 repetitions in one session for 4 weeks. The Statistical analysis will be performed through SPSS Software 21.


Eligibility criteria: Inclusion Criteria:

* Patients positive for provocative test ( Phalen's test, Wrist decompression test and tinnel test).

Exclusion Criteria:

* Inflammation around the wrist
* Tumor around the wrist
* Rheumatoid Arthritis
* Osteoporosis
* Joint Hypermobility

Primary outcomes:
measure: Pain at wrist joint
timeFrame: 4 weeks
measure: Wrist Range of Movement at wrist joint
timeFrame: 4 weeks
measure: Functional Ability at wrist joint
timeFrame: 4 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Faisalābad
country: Pakistan
facility: District Headquarters Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Sahreen Anwar, Ph.D
role: PRINCIPAL_INVESTIGATOR
References: