Clinical trial NCT06059937: Evaluation of Cardiovascular Risk After Preeclampsia in General Practitioners and Patients
Official title: Evaluation of Cardiovascular Risk After Preeclampsia in General Practitioners and Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Patients Hospitalized for Pre-eclampsia
Keywords: pre-eclampsia
cardiovascular risk
Lead sponsor: Central Hospital, Nancy, France
Sponsor class: OTHER
First posted: 2023-09-29
Enrollment: 155
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients ≥ 18 years of age who were hospitalized for preeclampsia

Brief summary: Pre-eclampsia is a disease characterized by placental damage leading to a cascade of complications during pregnancy. It is initially manifested by high blood pressure and the presence of albumin in the urine. It can lead to emergency hospitalization in severe cases and cause major complications or even death in the mother and the fetus.

Several studies observing the outcome of patients with pre-eclampsia have shown an increased long-term cardiovascular risk in these patients, justifying regular medical follow-up with the treating physician and specialists, mainly cardiologists.

The main objective of this research is to describe the cardiovascular risk assessment actions implemented by the treating general practitioner in the year following pre-eclampsia (blood pressure measurement in the office, self-measurement of blood pressure, ABPM, cardiological consultation, biological monitoring of blood (creatininemia, LDL, fasting glycemia) or urine (albuminurie/creatininurie ratio), and screening and management of possible smoking).


Eligibility criteria: Inclusion Criteria:

* Patients ≥ 18 years hospitalized for preeclampsia at the Nancy regional maternity hospital

Exclusion Criteria:

* Fetal death in utero;
* Adult Person subject to a legal protection measure (guardianship, curatorship, safeguard of justice);
* Person deprived of liberty by a judicial or administrative decision;
* Person subject to psychiatric care under constraint by virtue of articles L. 3212-1 and L. 3213-1 of the Public Health Code.

Primary outcomes:
measure: Performing a blood pressure measurement by the general practitioner
timeFrame: Up to one year following pre eclampsia
measure: Performing a self-measurement of blood pressure
timeFrame: Up to one year following pre eclampsia
measure: Performing a cardiological consultation
timeFrame: Up to one year following pre eclampsia
measure: Performing a ambulatory measurement of blood pressure
timeFrame: Up to one year following pre eclampsia
measure: Performing a biological monitoring of blood (creatinine, LDL cholesterol, fasting glucose, albuminuria creatinuria ratio)
timeFrame: Up to one year following pre eclampsia
measure: Screening and management of possible smoking
timeFrame: Up to one year following pre eclampsia
Secondary outcomes:
measure: Cardiovascular risk assessment by the general practitioner
timeFrame: Up to 5 years following pre eclampsia
measure: Cardiovascular risk assessment by the patient
timeFrame: Up to 5 years following pre eclampsia
measure: Knowledge of pre-eclampsia status
timeFrame: Up to 5 years following pre eclampsia
measure: Pre eclampsia information mode
timeFrame: Up to 5 years following pre eclampsia
measure: Performing a blood pressure measurement
timeFrame: Up to one year following pre eclampsia
measure: Performing a self-measurement of blood pressure
timeFrame: Up to one year following pre eclampsia
measure: Performing a cardiological consultation
timeFrame: Up to one year following pre eclampsia
measure: Performing a ambulatory measurement of blood pressure
timeFrame: Up to one year following pre eclampsia
measure: Performing a biological monitoring of blood (creatinine, LDL cholesterol, fasting glucose, albuminuria creatinuria ratio)
timeFrame: Up to one year following pre eclampsia
measure: Screening and management of possible smoking
timeFrame: Up to one year following pre eclampsia
measure: Rate of hypertension following pre-eclampsia
timeFrame: Up to 5 years following pre eclampsia
measure: Rate of stroke following pre-eclampsia
timeFrame: Up to 5 years following pre eclampsia
measure: Rate of coronary accident following pre-eclampsia
timeFrame: Up to 5 years following pre eclampsia
Other outcomes:
Locations:
city: Vandoeuvre les nancy
country: France
facility: CHRU de NANCY
Study officials:
affiliation: CHRU de NANCY
name: Nicolas GIRERD, MD-PhD
role: STUDY_CHAIR
References: