Clinical trial NCT05096793: Acute Supplementation With Beta-Alanine Improves Performance in Aerobic-anaerobic Transition Zones in Endurance Athletes
Official title: Acute Supplementation With Beta-Alanine Improves Performance in Aerobic-anaerobic Transition Zones in Endurance Athletes
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Beta-alanine
Keywords: beta-alanine
ergogenic aid
physical performance
aerobic-anaerobic transition zones
maximal aerobic speed
Lead sponsor: University of Americas
Sponsor class: OTHER
First posted: 2021-10-27
Enrollment: 12
Sex: MALE
Minimum age (years): 18
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: The experimental design applied was randomized cross-over and double-blind
Primary purpose: TREATMENT

Brief summary: The use of beta-alanine (BA) to increase physical performance is widely documented. However, the acute effect of this amino acid on maximal tests in the aerobic-anaerobic transition zone is still uncertain. The objective of this study was to determine the acute effect of low and high-dose BA trials on maximal aerobic speed (MAS) in endurance athletes. We hypothesized that high doses of BA have a greater effect than low doses, both compared to baseline. Twelve male endurance athletes volunteered for the study. The experimental design applied was randomized cross-over, double-blind. Treatment included three 6-minute run tests (6-MRT), the first as a baseline, then randomized 6-MRT with low (30 mg·kg-1) and high (45 mg·kg-1) dose BA trials. The 6-MRTs were separated by 72 hours. The main variable of the study was the distance (m) performed in the 6-MRT. Differences between tests were established through ANOVA and Tukey's multiple comparison tests (p \< 0.05).

Detailed description: In this original research, we determined the acute effect of low (30 mg·kg-1) and high-dose (45 mg·kg-1) BA trials on maximal aerobic speed (MAS) in endurance athletes. At the same time, we compared the effect size with of BA.

Eligibility criteria: Inclusion Criteria:

* The inclusion criterion was years of training for endurance events (participants had a minimum of two years running middle-distance and long-distance events).

Exclusion Criteria:

* The exclusion criterion was the inability to perform the 6-minute run test

Primary outcomes:
measure: 6-minute race test (meters)
timeFrame: at the end of the 6 minute test
Secondary outcomes:
measure: Lactate
timeFrame: at the end of the 6 minute test
measure: Heart Rate
timeFrame: at the end of the 6 minute test
Other outcomes:
Locations:
city: Viña del Mar
country: Chile
facility: Uamericas
Study officials:
affiliation: University of Americas
name: Hernán Cañon, Ph.D.
role: STUDY_DIRECTOR
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