Clinical trial NCT05741593: Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated with Antithrombotics for an Ischemic Stroke.
Official title: Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated with Antithrombotics for an Ischemic Stroke.
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Stroke
Keywords: Qualitative study
semi-structured interview
antithrombotic
stroke
medication adherence
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2023-02-23
Enrollment: 30
Sex: ALL
Minimum age (years): 65
Maximum age (years): 100
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients aged 65 and over, hospitalized for an ischemic stroke or a recurrence of ischemic stroke, being already treated with an antithrombotic treatment hospitalized at the Charpennes hospital with a plan to return home

Brief summary: Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. There are brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

Detailed description: Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. The probability of stroke recurrence is high: about 25% the first year , and 30 to 40% in the 5 years following the stroke. Recurrent strokes are responsible for significant disability, institutionalization, major neurocognitive disorders, and death.

In order to reduce the risk of stroke recurrence, multiple secondary prevention strategies have demonstrated their effectiveness, such as the prescription of drugs (in particular statins and antithrombotics), the establishment of a balanced diet, the practice of an activity physical, or even tobacco addiction.

However, the effectiveness of these strategies is optimal if and only if patients adhere to them.

In addition, previous studies have focused on the brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.

In elderly patients, other obstacles could have been identified by specific studies, such as cognitive, sensory, functional disorders or even isolation.

Eligibility criteria: Inclusion Criteria:

* Patients aged 65 and over
* Patients hospitalized for an ischemic stroke or a recurrence of ischemic stroke, already being treated with an antithrombotic treatment (antiplatelet agent or anticoagulant ) prior to the stroke
* Patients living at home and with a plan to return home.
* Patients who did not object to the study and who gave their consent for the recording of the interview

Exclusion Criteria:

* Patients with cognitive disorders or stroke sequelae that do not allow a semi-directive interview to be carried out (at medical discretion).
* Non-French speaking patients

Primary outcomes:
measure: Analysis of the verbatim from the transcription of the recorded interviews.
timeFrame: one year
Secondary outcomes:
measure: Analysis of verbatim statements from the transcription of recorded interviews on patients' representations and beliefs regarding antithrombotics
timeFrame: 15 to 60 minutes per patient
measure: Analysis of verbatim statements from the transcription of recorded interviews on patients' medication adherence to antithrombotics
timeFrame: 15 to 60 minutes per patient
measure: Analysis of verbatim statements from the transcription of recorded interviews on the impact of the occurrence of stroke or recurrence of stroke on medication adherence
timeFrame: 15 to 60 minutes per patient
measure: Analysis of verbatim statements from the transcription of recorded interviews on the obstacles and levers to medication adherence
timeFrame: 15 to 60 minutes per patient
Other outcomes:
Locations:
city: Villeurbanne
country: France
facility: institute of aging - Hôpital des Charpennes
Study officials:
References: