louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT05132959: The Morphometric Parameters of Shoulder and Supraspinatus Tendinosis
Official title: The Association Between The Morphometric Parameters of Shoulder and Supraspinatus Tendinosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Shoulder Pain
Tendinosis
Lead sponsor: Alanya Alaaddin Keykubat University
Sponsor class: OTHER
First posted: 2021-11-24
Enrollment: 100
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with shoulder pain due to shoulder pathology and another pathology and who have MRI images of the shoulder were recrutied into the study.

Brief summary: Supraspinatus tendinosis one of the most common pathologies of the musculoskeletal system.The aim of this study to investigate the relationship between supraspinatus tendinosis and shoulder morphology with magnetic resonance imaging (MRI).

Detailed description: Supraspinatus tendinosis one of the most common pathologies of the musculoskeletal system. It affects 15-50% of the population and its prevalence increases with age. It can lead to useful disability as well as ease of life. Weight, old age and traumas as recurrent risk for SS tendosis. In the literature, there are a large number of small and small numbers among the biology of supraspinologicus tears .The aim of this study to investigate the relationship between supraspinatus tendinosis and shoulder morphology with magnetic resonance imaging (MRI).

Eligibility criteria: Inclusion Criteria:

* Patients with shoulder pain or healthy controls

Exclusion Criteria:

* Patients with a history of shoulder surgery or trauma, inflammation of the shoulder joint, inflammatory arthritis, space-occupying mass lesions, rupture of the supraspinatus tendon or calcific tendinitis were excluded from the study.

Primary outcomes:
measure: Coracoacromial ligament thickness
timeFrame: three months
measure: Acromial angle (delta angle)
timeFrame: three months
measure: Acromioglenoid angle
timeFrame: three months
measure: Axial supraspinatus glenoid angle
timeFrame: at the same time
measure: Coronal supraspinatus glenoid angle
timeFrame: three months
measure: Acromiohumeral distance
timeFrame: three months
measure: Coracoacromial arch angle
timeFrame: three months
Secondary outcomes:
Other outcomes:
Locations:
city: Antalya
country: Turkey
facility: Alanya Alaaddin Keykubat University
Study officials:
References:
Clinical trial NCT04536259: Assessing People's Hospital Outpatient Appointment Preferences in the United Kingdom
Official title: Assessing People's Hospital Outpatient Appointment Preferences in the United Kingdom
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hospital Outpatient Clinics
Chronic Disease
Lead sponsor: University of Warwick
Sponsor class: OTHER
First posted: 2020-09-02
Enrollment: 1481
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Consenting participants be randomly assigned to one of three groups in a 1:1:1 fashion. Each group will be asked to imagine receiving an invitation to attend a hospital outpatient appointment by video or in-person. In the first group, the proposed attendance mode will be by video. In the second group, the proposed attendance mode will be in-person. In the third group, participants will simply be asked to select which mode of attendance they prefer: video or in-person.
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The sustainability of the United Kingdom's National Health Service's (NHS) is threatened immediately by Covid-19 and continually by an increasing prevalence of long-conditions that cannot be cured but can be maintained. Shifting traditional face-to-face outpatient appointments to remote video consultations may help the NHS continue to serve patients efficiently. While much research has examined healthcare providers' attitudes and beliefs about remote video consultations, less has attempted to understand how NHS service providers should invite patients to attend them. The present study examines how the framing of an invitation to attend a hospital outpatient appointment by video influences the proportion of people who agree to attend by video. It also explores some of the barriers and facilitators people may experience to attending appointments by video across diagnostic complexities and age groups. The results of this study should help hospitals better present patients with the option to attend video consultations where appropriate, and provide support to mitigate common barriers to people's willingness to give video consultations a go.


Eligibility criteria: Inclusion Criteria:

All participants will:

* be 18 years old or older;
* be resident in the United Kingdom; and
* indicate having been diagnosed with a chronic diseases such as diabetes, heart disease, stroke etc.

Exclusion Criteria:

* be less than 18 years old;
* not be resident in the United Kingdom; and
* not indicate having been diagnosed with a chronic diseases such as diabetes, heart disease, stroke etc.

Primary outcomes:
measure: Response to the outpatient invitation
timeFrame: One day
Secondary outcomes:
Other outcomes:
Locations:
city: Coventry
country: United Kingdom
facility: Kelly Schmidtke
state: West Midlands
Study officials:
affiliation: University of Warwick
name: Kelly A Schmidtke, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00316459: Study Evaluating the Effects of Multiple Oral Doses of ERB-041 on Cardiac Repolarization in Healthy Subjects
Official title: A Randomized, Double-Blind, Placebo and Moxifloxacin (Open-Label) Controlled, 4-Period, Crossover Study of the Effects of Multiple Oral Doses of ERB-041 on Cardiac Repolarization in Healthy Subjects
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Healthy
Long QT Syndrome
Keywords: Healthy
Cardiac
Pharmacokinetics
Lead sponsor: Wyeth is now a wholly owned subsidiary of Pfizer
Sponsor class: INDUSTRY
First posted: 2006-04-20
Enrollment: 64
Sex: ALL
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: To assess the effect of ERB-041 after multiple oral doses on cardiac repolarization as assessed by the QTc interval.


Eligibility criteria: Inclusion Criteria:

* Healthy as determined by the investigator on the basis of medical history, physical examination, clinical laboratory test results, vital signs, and ECG.
* Nonsmoker or smoker of fewer than 10 cigarettes (half a pack) per day as determined by history.

Exclusion Criteria:

* A family history of long QT syndrome and/or cardiac death.
* Any significant cardiovascular, hepatic, renal, respiratory, gastrointestinal, endocrine, immunologic, dermatologic, hematological, neurological, or psychiatric disease.

Primary outcomes:
measure: To assess the effect of ERB-041 after multiple oral doses on cardiac repolarization as assessed by the QTc interval
Secondary outcomes:
measure: To characterize pharmacokinetic and pharmacodynamic relationships as it relates to QTc.
Other outcomes:
Locations:
city: Miami
country: United States
state: Florida
Study officials:
affiliation: Wyeth is now a wholly owned subsidiary of Pfizer
name: Medical Monitor
role: STUDY_DIRECTOR
References:
Clinical trial NCT04928859: Study on Efficacy and Safety of Human Albumin in Burn Shock Recovery
Official title: Study on Efficacy and Safety of Human Albumin in Burn Shock Recovery
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Burns Shock
Keywords: burns; shock; recovery; human albumin; effect
Lead sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Sponsor class: OTHER
First posted: 2021-06-16
Enrollment: 364
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The patients who admitted to the burn ward of the Second Affiliated Hospital, School of Medicine, Zhejiang University and needed fluid resuscitation were identified during the period of January 2011 to December 2018.

Brief summary: To explore the effects and safety of human albumin in burn shock recovery, and then provide a theoretical basis for its rational use.

Detailed description: A retrospective case-control study was conducted. Patients who admitted to the burn ward and needed fluid resuscitation during the period of January 2011 to December 2018 in our unit were identified. Patients were divided into two groups according to the severity of burns, the patients with a 20%\<TBSA≤50% constituted the moderate and severe burn group, the patients with a TBSA\>50% constituted the severest burn group, and then the patients who used albumin for resuscitation constituted the albumin group, the patients who did not use albumin constituted the control group. The primary outcome was mortality, and the secondary outcomes included hospital stay, ventilator supporting, fluid use, and complications.

Eligibility criteria: Inclusion Criteria:

* Age ≥ 18
* TBSA≥ 20% （TBSA，the total burn area.）
* Admitted to hospital within 24 hours after injury.

Exclusion Criteria:

* STB ≥ 33 μ mol/L
* Cr ≥ 171 μ
* Urine output l\< 500 ml / 24 h
* Pregnant and lactating women
* Severe combined injury
* Glucocorticoids users
* Immunosuppressants users
* Patients survived less than 48 hours

Primary outcomes:
measure: the mortality of the patients
timeFrame: during the patients's hospitalization, an average of 1-2 month.
Secondary outcomes:
measure: the length of the patients's hospital stay
timeFrame: during the patients's hospitalization, an average of 1-2 month.
measure: the number of patients that using ventilators
timeFrame: during the patients's hospitalization, an average of 1-2 month.
measure: Volume of fluid used for resuscitationVolume of fluid used for resuscitation the volume of the patients's resuscitation fluid
timeFrame: during the patients's hospitalization, an average of 1-2 month.
measure: the number of complications that the patients occurred
timeFrame: during the patients's hospitalization, an average of 1-2 month.
Other outcomes:
Locations:
Study officials:
affiliation: Second Affiliated Hospital, School of Medicine, Zhejiang University
name: Hai-Bin Dai, doctor
role: STUDY_DIRECTOR
References:
Clinical trial NCT05573659: Capillary Refill Time Calculated With a Video-assisted Method Has a Better Reproducibility Than Visual Method in Critically Ill Patients
Official title: Capillary Refill Time Calculated With a Video-assisted Method Has a Better Reproducibility Than Visual Method in Critically Ill Patients a Prospective Monocentric Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Intensive Care Unit
Mortality
Reliability
Keywords: capillary refill time
intensive care unit
mortality
reliability
Lead sponsor: Centre Hospitalier Universitaire, Amiens
Sponsor class: OTHER
First posted: 2022-10-10
Enrollment: 59
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Capillary refill time is the time it takes for the skin to regain its initial colour after moderate pressure. It is usually performed on the patient index finger, middle finger or ring finger with the examiner's thumb and index finger for five seconds, three measurements having to be averaged. Capillary refill time has a dependent operator character, but it has been shown to be accurately correlated with 14-day mortality in septic shock, hospitalisation need in pediatric population.

The purpose of this project is to show that capillary refill time obtained by a video-assisted method has a better inter- and intra-observer reproducibility than capillary refill time obtained by a visual method.


Eligibility criteria: Inclusion Criteria:

* Age \> 18 years
* hospitalized in ICU
* Patient or Family /relative with Inclusion Authorization

Exclusion Criteria:

* Pregnant or lactating women
* Under protection (guardianship, curators, reinforced curators)

Primary outcomes:
measure: Variation of measure of capillary refill time in visual assisted capillary refill time group.
timeFrame: 28 days
measure: Variation of measure of capillary refill time in video assisted capillary refill time group.
timeFrame: 28 days
measure: Variation of measure of capillary refill time between both groups.
timeFrame: 28 days
Secondary outcomes:
Other outcomes:
Locations:
city: Amiens
country: France
facility: CHU Amiens Picardie
Study officials:
References:
Clinical trial NCT04733859: Using Red Djulis Products Can Improve Skin Conditions
Official title: Using Red Djulis Products Can Improve Skin Conditions
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Skin Condition
Lead sponsor: TCI Co., Ltd.
Sponsor class: INDUSTRY
First posted: 2021-02-02
Enrollment: 30
Sex: ALL
Minimum age (years): 20
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Hypothesis: Using red djulis products can improve skin conditions


Eligibility criteria: Inclusion Criteria:

1. Dry skin
2. Rough skin
3. Large pores
4. Dark yellow complexion
5. Sagging skin

Exclusion Criteria:

1. Skin disorders
2. Liver diseases
3. Kidney diseases
4. Allergy to cosmetics, drugs, or foods
5. Pregnant and lactating women
6. People who had any cosmetic procedures before 4 weeks of the study
7. Area of facial spot over 3 cm2
8. Vegan
9. People who took collagen supplements in the past 3 months.

Primary outcomes:
measure: skin moisture
timeFrame: up to 8 week
measure: skin elasticity
timeFrame: up to 8 week
measure: skin gloss
timeFrame: up to 8 week
measure: skin spot
timeFrame: up to 8 week
measure: skin wrinkle
timeFrame: up to 8 week
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Research & Design Center, TCI CO., Ltd
state: Neipu Township
Study officials:
affiliation: Chia Nan University of Pharmacy ＆ Science
name: Chia-Hua Liang, Ph.D
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01438359: A Drug-Drug Interaction Study of Furosemide and PA21
Official title: A Single-centre, Open-label, Three-period Study of the Pharmacokinetic Effect of PA21 on Furosemide in Healthy Male and Female Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Healthy
Keywords: Drug-drug interaction
Pharmacokinetics
PA21
Drug Interaction Potentiation
Lead sponsor: Vifor Pharma
Sponsor class: INDUSTRY
First posted: 2011-09-22
Enrollment: 42
Sex: ALL
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this study is to determine if Furosemide is affected by PA21.


Eligibility criteria: Inclusion Criteria:

* Healthy volunteers
* Written informed consent

Exclusion Criteria:

* No significant medical conditions
* Pregnancy

Primary outcomes:
measure: Effect of PA21 on Furosemide
timeFrame: PK assessment on Day 0, 11, and 22: pre-dose, 0.25, 0.5, 1, 1.5, 2, 2.5, 3, 4, 5, 6, 8, 12, 24, 48 hrs post furosemide dose
Secondary outcomes:
Other outcomes:
Locations:
city: Anaheim
country: United States
facility: ACRI - Phase 1
state: California
Study officials:
affiliation: ACRI - Phase 1 (Advanced Clinical Research Institute)
name: Peter J Winkle, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06991959: Can Education for Rural Women Lift the Fog Behind Closed Doors?
Official title: Can Education for Rural Women Lift the Fog Behind Closed Doors?
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Contraception
Sexually Transmitted Diseases
Keywords: Rural
Education
Knowledge
Attitudes
Lead sponsor: Trakya University
Sponsor class: OTHER
First posted: 2025-05-28
Enrollment: 72
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The aim of this study was to investigate the effect of family planning and sexually transmitted diseases education given to rural women on their level of knowledge and attitudes towards reproductive health and family planning. Design: The prospective, randomized controlled study


Eligibility criteria: Inclusion Criteria:

* Women who can speak Turkish,
* Are older than 18 years of age,
* Do not have a diagnosis of hearing impairment,
* Live with their husband/partner,
* Have an active sexual life,
* Live in the districts within the borders of Bartın province,
* Do not have a type of cancer that may affect sexual function,
* Have not received family planning and sexually transmitted diseases training before,
* Have written informed consent,
* Volunteer to participate in the study

Exclusion Criteria:

* Women who received family planning and sexually transmitted diseases education from another counselor during the study period,
* Did not participate in the post-test,
* Did not volunteer to participate in the study

Primary outcomes:
measure: Sexually Transmitted Diseases Knowledge Scale
timeFrame: change from before implamentation patent and after 1st day of practice.
measure: Reproductive Health and Family Planning Attitude Scale
timeFrame: change from before implamentation patent and after 1st day of practice.
Secondary outcomes:
Other outcomes:
Locations:
city: Bartın
country: Turkey
facility: Bartın University
Study officials:
References:
Clinical trial NCT00201500: Left Ventricular and Endothelial Function in Preeclampsia
Official title: Left Ventricular and Endothelial Function in Preeclampsia, a Case Control Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Preeclampsia
Lead sponsor: Norwegian University of Science and Technology
Sponsor class: OTHER
Collaborators: name: Helse Nord-Trøndelag HF
First posted: 2005-09-20
Enrollment: 39
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Sampling method: PROBABILITY_SAMPLE
Study population: Women with preeclampsia and women with normotensive pregnancies.

Brief summary: The purpose of this study is (1) to examine whether the left ventricular function is impaired in women with preeclampsia relative to healthy pregnant controls, (2) to examine whether the endothelial function is impaired in women with preeclampsia relative to healthy pregnant controls, and (3) to examine whether there is a post partum impairment in left ventricular and endothelial function.


Eligibility criteria: Inclusion Criteria:

* \>18 years of age
* Case: Clinical diagnosis of preeclampsia,
* Control: Systolic BP \<140 mmHg and diastolic BP \<90 mmHg

Exclusion Criteria:

* Known hypertension or other cardiovascular disease
* Diabetes/gestational diabetes
* Multiple gestation

Primary outcomes:
measure: Left Ventricular Function
timeFrame: 3 months
measure: Endothelial Function
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Trondheim
country: Norway
facility: NTNU
Study officials:
affiliation: Norwegian University of Science and Technology
name: Stig A Slørdahl, Professor
role: STUDY_CHAIR
References:
citation: Tyldum EV, Backe B, Stoylen A, Slordahl SA. Maternal left ventricular and endothelial functions in preeclampsia. Acta Obstet Gynecol Scand. 2012 May;91(5):566-73. doi: 10.1111/j.1600-0412.2011.01282.x.
Clinical trial NCT05473000: Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise
Official title: Investigating Susceptibility of Cardiorespiratory Responses to Ozone During Cycling Exercise Based on Resting Ozone Exposure
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Ozone Exposure During Rest and Exercise
Keywords: Ozone
Air pollution
Exercise
Cycling
Susceptibility
Ventilation
Lead sponsor: University of British Columbia
Sponsor class: OTHER
Collaborators: name: Natural Sciences and Engineering Research Council, Canada
First posted: 2022-07-25
Enrollment: 20
Sex: MALE
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: Ground level ozone (O3) is a common airborne pollutant that is well recognized to cause negative respiratory symptoms and impair pulmonary function. The proposed study aims to have participants perform submaximal and maximal cycling exercise protocols exposed to both O3 and room air in a crossover design to evaluate how ventilatory patterns, pulmonary function, development of symptoms, and cycling performance are impacted by O3 exposure. Additionally, the investigators look to compare responses between O3 at rest and during exercise to predict which subjects may be most susceptible to adverse response, as considerable interindividual variability exists.


Eligibility criteria: Inclusion Criteria:

* Healthy males between the age of 18 and 50
* Currently training and/or competing in endurance sport
* VO2max \>60 ml/kg/min
* Able to communicate sufficiently using the English language

Exclusion Criteria:

* History of smoking
* Upper respiratory tract infection within the last 4 weeks
* Presence of any chronic respiratory disease

Primary outcomes:
measure: Time-to-exhaustion on Maximal Cycling Bout
timeFrame: From the beginning of the maximal constant work-rate cycling bout until volitional exhaustion occurs (roughly 1-5 minutes)
Secondary outcomes:
Other outcomes:
Locations:
city: Vancouver
country: Canada
facility: University of British Columbia
state: British Columbia
Study officials:
affiliation: University of British Columbia
name: Michael Koehle, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: