Clinical trial NCT02939885: fMRI Study of Brain Mechanisms Related to Emotions
Official title: Imagerie Fonctionnelle cérébrale: Aspects Normaux et Pathologiques
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Neuroimaging
Lead sponsor: Centre Hospitalier Universitaire de Besancon
Sponsor class: OTHER
Collaborators: name: University of Franche-Comté
First posted: 2016-10-20
Enrollment: 22
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Participants came after invitation to volunteer. They are mainly students from our university.

Brief summary: The purpose of the study is to better define and understand the brain mechanisms related to emotional and cognitive dimensions using odorous stimuli, gustatory stimuli, visual stimuli and auditory stimuli using functional Magnetic Resonance Imaging (fMRI).


Eligibility criteria: Inclusion Criteria:

* right-handed
* Healthy Volunteers

Exclusion Criteria:

* those applied for an magnetic resonance examination

Primary outcomes:
measure: Cerebral activation of subjects using Blood Oxygenation Level Dependant (BOLD) contrast imaging
timeFrame: at admission
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Bonnet L, Comte A, Tatu L, Millot JL, Moulin T, Medeiros de Bustos E. The role of the amygdala in the perception of positive emotions: an "intensity detector". Front Behav Neurosci. 2015 Jul 7;9:178. doi: 10.3389/fnbeh.2015.00178. eCollection 2015.
citation: Comte A, Gabriel D, Pazart L, Magnin E, Cretin E, Haffen E, Moulin T, Aubry R. On the difficulty to communicate with fMRI-based protocols used to identify covert awareness. Neuroscience. 2015 Aug 6;300:448-59. doi: 10.1016/j.neuroscience.2015.05.059. Epub 2015 May 30.
citation: Gabriel D, Henriques J, Comte A, Grigoryeva L, Ortega JP, Cretin E, Brunotte G, Haffen E, Moulin T, Aubry R, Pazart L. Substitute or complement? Defining the relative place of EEG and fMRI in the detection of voluntary brain reactions. Neuroscience. 2015 Apr 2;290:435-44. doi: 10.1016/j.neuroscience.2015.01.053. Epub 2015 Jan 30.
citation: Pazart L, Comte A, Magnin E, Millot JL, Moulin T. An fMRI study on the influence of sommeliers' expertise on the integration of flavor. Front Behav Neurosci. 2014 Oct 16;8:358. doi: 10.3389/fnbeh.2014.00358. eCollection 2014.
citation: Galliot E, Comte A, Magnin E, Tatu L, Moulin T, Millot JL. Effects of an ambient odor on brain activations during episodic retrieval of objects. Brain Imaging Behav. 2013 Jun;7(2):213-9. doi: 10.1007/s11682-012-9218-8.
citation: Billot PE, Comte A, Galliot E, Andrieu P, Bonnans V, Tatu L, Gharbi T, Moulin T, Millot JL. Time course of odorant- and trigeminal-induced activation in the human brain: an event-related functional magnetic resonance imaging study. Neuroscience. 2011 Aug 25;189:370-6. doi: 10.1016/j.neuroscience.2011.05.035. Epub 2011 May 20.
citation: Lombion S, Comte A, Tatu L, Brand G, Moulin T, Millot JL. Patterns of cerebral activation during olfactory and trigeminal stimulations. Hum Brain Mapp. 2009 Mar;30(3):821-8. doi: 10.1002/hbm.20548.