Clinical trial NCT05988944: The Hand Functions In Cerebral Palsy
Official title: Which One is The Most Effective On The Hand Functions In Cerebral Palsy: Constraint-Induced Movement Therapy or Constraint-Induced Movement Therapy With Virtual Reality? A Randomized Controlled Trial.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cerebral Palsy
Hand Functions
Keywords: Hand Functions
Virtual Reality
Constraint-Induced Movement Therapy
Cerebral Palsy
Rehabilitation
Lead sponsor: Uludag University
Sponsor class: OTHER
First posted: 2023-08-14
Enrollment: 45
Sex: ALL
Minimum age (years): 8
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The hand motor functions are very important in the daily life activities, educational, and social participation of children. Losing The hand motor functions limit these activities and participation. Constraint-induced movement therapy (CIMT) or virtual reality (VR) therapy has often been preferred to improve the hand's motor functions.

Detailed description: CIMT and VR are used to improve the motor functions of the hand in cerebral palsy (CP). The aim of this study was to compare the effects of CIMT-VR use and only CIMT use on hand functions in children with hemiparetic cerebral palsy. Hand function and performance were evaluated with the Jebsen-Taylor and Moberg pick-up tests. All evaluations were made twice; before the first therapy and after six weeks. Children with hemiparetic CP were divided into three groups randomly (Traditional techniques (TT), TT+CIMT, and TT+CIMT+VR).

Eligibility criteria: The inclusion criteria of the study were determined to be

* aged 8 to 18 years,
* diagnosed with hemiparetic CP,
* being level 2 or 3 according to the gross motor function measurement scale and the manual ability classification system.

The exclusion criteria of the study were,

* severe cognitive dysfunction that rendered them unable to perform simple tasks (e.g., reaching, grasping),
* having pharmacologic medicine for spasticity,
* having botulinum toxin A injections in the last 6 months,
* having upper extremity surgery,
* having visual and/or auditory problems which affect therapy or evaluation.

Primary outcomes:
measure: The Jebsen-Taylor Test
timeFrame: this evaluation was done twice; before the first therapy and after six weeks by the same physiotherapist.
measure: Moberg pick-up test
timeFrame: this evaluation was done twice; before the first therapy and after six weeks by the same physiotherapist.
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Uskudar Universty
Study officials:
affiliation: Uskudar University
name: Esin KADIKOYLU, Pt
role: STUDY_CHAIR
affiliation: Uskudar University
name: Eren DEMIRAYAK, Pt
role: STUDY_CHAIR
affiliation: Uludag University
name: Cetin Sayaca, Assoc. Prof.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Elliott C, Reid S, Hamer P, Alderson J, Elliott B. Lycra((R)) arm splints improve movement fluency in children with cerebral palsy. Gait Posture. 2011 Feb;33(2):214-9. doi: 10.1016/j.gaitpost.2010.11.008. Epub 2010 Dec 4.
citation: Hoare BJ, Wallen MA, Thorley MN, Jackman ML, Carey LM, Imms C. Constraint-induced movement therapy in children with unilateral cerebral palsy. Cochrane Database Syst Rev. 2019 Apr 1;4(4):CD004149. doi: 10.1002/14651858.CD004149.pub3.
citation: Sakzewski L, Ziviani J, Boyd R. Systematic review and meta-analysis of therapeutic management of upper-limb dysfunction in children with congenital hemiplegia. Pediatrics. 2009 Jun;123(6):e1111-22. doi: 10.1542/peds.2008-3335. Epub 2009 May 18.
citation: Brady K, Garcia T. Constraint-induced movement therapy (CIMT): pediatric applications. Dev Disabil Res Rev. 2009;15(2):102-11. doi: 10.1002/ddrr.59.
citation: Jung SH, Song SH, Kim SD, Lee K, Lee GC. Does virtual reality training using the Xbox Kinect have a positive effect on physical functioning in children with spastic cerebral palsy? A case series. J Pediatr Rehabil Med. 2018;11(2):95-101. doi: 10.3233/PRM-160415.