Clinical trial NCT03698578: Creatine Kinase Levels and Clinical and Functional Parameters in Parajiu-jitsu Athletes
Official title: Correlation Between Creatine Kinase Levels and Clinical and Functional Parameters in the Moments Following the Fight in Parajiu-jitsu Athletes: A Controlled Clinical Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Healthy
Deficiency Diseases
Lead sponsor: São Paulo State University
Sponsor class: OTHER
First posted: 2018-10-09
Enrollment: 12
Sex: MALE
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SCREENING

Brief summary: Introduction: Evidence indicates that muscle damage caused by exercise can lead to functional, biochemical and clinical damage. Therefore, it is pertinent to perform investigations related to the muscle damage marker, creatine kinase with clinical and functional responses. These outcomes encompass an intrinsic potential for understanding the real magnitude of interpretation of classic signals in athletic environments and monitoring of athletes, contributing to specific actions. Objective: To verify the correlation between clinical signs (pain and perception of recovery), functional (muscular strength) and the behavior of CK levels, in the moments following a simulated fight. METHODS: Six male parajiu-jitsu practitioners (34-44 years) were included in the study. The participants attended the collection site 4 times, with a 24-hour interval between sessions, characterizing the following collection moments: baseline, post-exertion, 24, 48 and 72 hours after the simulated fight. Data on pain (visual analogue scale - EVA), perception of recovery (Likert Scale), muscle strength (Dynamometry) and blood samples for CK analysis were collected. All parameters described were measured at all times of collection. For the analysis of the association between behavior of CK levels, clinical and functional variables, the Odds Ratio test and 95% confidence interval were used. For the gross values, the Pearson test was used according to the normality of the data.

Detailed description: Participants will be intentionally allocated into two groups, G1 consisting of professional athletes and G2 consisting of amateur athletes. This division was carried out to guarantee homogeneous stratification between participants with level of conditioning and similar training. The anonymity of the participants will be guaranteed. There will be masking of the participants, investigator and evaluator of the results that were blind to the hypotheses and allocation in groups, adopted in the study. All participants regularly attended the same training center and no sports injuries that might compromise athletic performance will be reported during the survey.

Eligibility criteria: Inclusion Criteria:

* Jiu-Jitsu paratroopers were included. To be included in the study participants should report absence of anemia, inflammation, diabetes, cardiovascular disease, and musculoskeletal injuries in the six months prior to data collection. In addition, participants were instructed to refrain from anti-inflammatory drugs, analgesics, alcoholic beverages, and tobacco and did not perform any extra exercise during the study.

Exclusion Criteria:

* withdrawal of participants for personal reasons

Primary outcomes:
measure: creatine kinase
timeFrame: post fight - 72 hours
Secondary outcomes:
measure: perception of recovery
timeFrame: post fight - 72 hours
measure: muscle pain
timeFrame: post fight - 72 hours
Other outcomes:
Locations:
city: Barra do Garças
country: Brazil
facility: Rayana Loch Gomes
state: Mount
Study officials:
affiliation: Paulista State University
name: Jessica Michelletti, master
role: STUDY_CHAIR
References: