louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06694961: Knowledge of Adolescent Well-care Visits and Attitudes Amongst Physicians
Official title: Knowledge of Adolescent Well-care Visits and Attitudes Amongst Pediatricians and Family Medicine Physicians Across Al-Ain City
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Adolescent Health
Keywords: knowledge
Attitude
Pediatricians
family medicine
Physician
Adolescent
well-care visits
Lead sponsor: Abu Dhabi Health Services Company
Sponsor class: OTHER_GOV
First posted: 2024-11-19
Enrollment: 100
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Pediatricians and family medicine physicians

Brief summary: The goal of this observational study is to be a quality improvement project to assess the knowledge, attitude towards adolescent well visit screening and preventing counseling amongst pediatrician and family medicine physicians in Al-Ain city. We will be conducting an online survey covering general aspects regarding adolescent well-being visits, before and after providing necessary education to the participants

Detailed description: This is a quality improvement project with the following fields to be studied:

* Knowledge of recommendations regarding adolescent well-care visits amongst pediatricians \& primary care physicians in Al-Ain City.
* Compliance of pediatricians \& primary care physicians towards adolescent well-care visits.
* Effectiveness in conducting educatory sessions for physicians to improve the quality of adolescent well-care visits.
* Adolescent behaviour \& knowledge of the availability of well-care visits.
* Adolescent \& family satisfaction in attendance of well-care visits.
* An online survey covering general aspects regarding adolescent well-being visits will be shared with pediatricians and family medicine physicians, before and after providing necessary education to the participants.

Eligibility criteria: Inclusion Criteria:

* Pediatricians and family medicine physicians at Al Ain City SEHA Hospitals.

Exclusion Criteria:

* Pediatricians and family medicine physicians who are not part of Al Ain City SEHA Hospitals.

Primary outcomes:
measure: Knowledge of physicians towards adolescent well care visits
timeFrame: 1 year
measure: Attitudes of physicians towards adolescent well-care visits
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Al Ain
country: United Arab Emirates
facility: Tawam Hospital
state: Abu Dhabi
Study officials:
affiliation: Abu Dhabi Health Services Co. -SEHA
name: Alaa S Mehair, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Abu Dhabi Health Services Co-SEHA
name: Najla S AlKuawiti, MD
role: STUDY_CHAIR
References:
Clinical trial NCT04993261: An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors
Official title: Evaluation of Dual Energy CT for the Detection of Gastrointestinal Carcinoids
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: EARLY_PHASE1
Conditions: Carcinoid Syndrome
Carcinoid Tumor
Digestive System Neuroendocrine Tumor G1
Metastatic Carcinoid Tumor
Lead sponsor: M.D. Anderson Cancer Center
Sponsor class: OTHER
First posted: 2021-08-06
Enrollment: 71
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: This trial studies the use of a special type of computed (CT) scan called dual energy CT in detecting gastrointestinal carcinoid tumors. CT is an imaging technique that uses x-rays and a computer to create images of areas inside the body. Dual energy computed tomography is a technique used during routine CT scans to help obtain and process the image after the scan is complete. Doctors want to learn if dual energy computed tomography can help improve the detection of carcinoid tumors during routine CT scans.

Detailed description: PRIMARY OBJECTIVES:

I. Evaluate prospectively the sensitivity and specificity of dual energy computed tomography (CT) in detecting primary gastrointestinal (GI) carcinoid.

OUTLINE:

Patients undergo one dual energy CT scan during scheduled CT scan.

Eligibility criteria: Inclusion Criteria:

* Patients with: clinical features of carcinoid syndrome (or) increased serum and urinary markers suggestive of carcinoid (or) endoscopic biopsy proven carcinoid (or) metastases which are biopsy proven as carcinoid.
* Patient is scheduled to have a clinically indicated staging CT exam.
* Patients who have signed their informed consent form to undergo the study.

Exclusion Criteria:

* Patients who have already had their primary GI carcinoid resected.
* Contraindication to intravenous contrast agents (e.g. allergy, renal failure, dialysis, pregnancy etc.).
* Pregnant patients.

Primary outcomes:
measure: Sensitivity and specificity of dual energy computed tomography in detecting primary gastrointestinal carcinoid tumors
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Houston
country: United States
facility: M D Anderson Cancer Center
state: Texas
Study officials:
affiliation: M.D. Anderson Cancer Center
name: Ajaykumar Morani
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02323061: Brain Computer Interface（BCI） System for Stroke Rehabilitation
Official title: Brain Computer Interface（BCI） System for Stroke Rehabilitation
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Lead sponsor: Chinese University of Hong Kong
Sponsor class: OTHER
First posted: 2014-12-23
Enrollment: 25
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A BCI system for stroke subjects will be designed in an attempt to train the motor-related areas in their brains responsible for hand open/close function. A robot hand will be used and controlled by the system in real time based on EEG pattern for identification of motion intention for hand movements in the motor cortex. A randomized controlled trial study design will be adopted. All subjects will be assessed by clinical assessments including FMA and neuroimaging assessments using multimodal MR techniques before and after the training to evaluate training effectiveness.


Eligibility criteria: Inclusion Criteria:

1. Sufficient cognition to follow simple instructions, as well as understand the content and purpose of the experiment;
2. Subcortical ischemic lesion within the territory of the middle cerebral artery;
3. Have moderate to severe motor disability at the paretic upper limb (assessed by Fugl-Meter Assessment (FMA), Modified Ashworth Score of fingers (MAS), and Action Research Arm Test(ARAT)).
4. Hemiparesis resulting from a single unilateral lesion of the brain with onset at least 6 months before data collection.

Exclusion Criteria:

1. Severe hand spasticity, open hand wound or hand deformity;
2. Visual field deficits;
3. Aphasia, neglect, and apraxia,
4. Participation in any therapeutic treatment ("outside therapy") performed with the paralyzed arm during the planned study - including baseline and follow up.
5. History of alcohol, drug abuse or epilepsy,
6. Bilateral infracts,
7. Uncontrolled medical problems,
8. Serious cognitive deficits,
9. Other MRI contraindications

Primary outcomes:
measure: FMA-UE
timeFrame: 6-month followup
measure: ARAT
timeFrame: 6-month followup
Secondary outcomes:
measure: MAS
timeFrame: 6-month followup
measure: MRI
timeFrame: 6-month followup
Other outcomes:
Locations:
city: Hong Kong
country: Hong Kong
facility: Department of Biomedical Engineering, The Chinese University of Hong Kong
Study officials:
References:
citation: Lau CCY, Yuan K, Wong PCM, Chu WCW, Leung TW, Wong WW, Tong RKY. Modulation of Functional Connectivity and Low-Frequency Fluctuations After Brain-Computer Interface-Guided Robot Hand Training in Chronic Stroke: A 6-Month Follow-Up Study. Front Hum Neurosci. 2021 Jan 20;14:611064. doi: 10.3389/fnhum.2020.611064. eCollection 2020.
citation: Yuan K, Wang X, Chen C, Lau CC, Chu WC, Tong RK. Interhemispheric Functional Reorganization and its Structural Base After BCI-Guided Upper-Limb Training in Chronic Stroke. IEEE Trans Neural Syst Rehabil Eng. 2020 Nov;28(11):2525-2536. doi: 10.1109/TNSRE.2020.3027955. Epub 2020 Nov 6.
Clinical trial NCT02602561: Effects of HMB Supplementation on Recovery Following ACL Surgery
Official title: Effects of HMB Supplementation on Muscle Mass Following ACL Reconstructive Surgery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: ACL Injury
Keywords: HMB
beta-hydroxy-beta-methylbutyrate
ACL
surgery
muscle mass
Lead sponsor: Metabolic Technologies Inc.
Sponsor class: INDUSTRY
Collaborators: name: Iowa State University
First posted: 2015-11-11
Enrollment: 4
Sex: ALL
Minimum age (years): 18
Maximum age (years): 49
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised. Reconstructive surgery is often necessary to repair the damage which is then followed by a regimen of physical therapy in order to regain full activity. Nutritional intervention after the surgery could help the patient maintain muscle mass during recovery, thus allowing for a quicker return to normal activity.

Detailed description: Beta-hydroxy-beta-methylbutyrate (HMB) is a nutritional supplement shown to improve muscle mass with exercise, and also in muscle loss conditions caused by a decrease in physical activity. Participants will be recruited who will undergo reconstructive surgery for a complete ACL tear and will then enter a standard physical therapy program during a six week recovery period. Subjects will receive either HMB or a placebo supplement during the recovery period. Muscle mass will be measured two weeks prior to the surgery and again after the recovery period using an InBody 720 body composition analyzer. Additionally, the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire will be administered as a measure of recovery and activity level during the study.

Eligibility criteria: Inclusion Criteria:

* Complete anterior cruciate ligament (ACL) tear
* Will benefit from ACL reconstructive surgery
* Are able to participate in the physical therapy program
* No previous major knee injuries or surgeries
* No health conditions affecting muscle mass

Exclusion Criteria:

* Incomplete ACL tear
* Have multiple or bilateral ligament tears
* Are unable to participate in the physical therapy program
* Have had previous major knee injuries or surgeries
* Have health conditions affecting muscle mass

Primary outcomes:
measure: Skeletal Muscle Mass by impedance measurement using the InBody 720 body composition analyzer
timeFrame: Six Weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Ames
country: United States
facility: Iowa State University
state: Iowa
Study officials:
affiliation: Metabolic Technologies Inc.
name: John A Rathmacher, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00178061: Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder
Official title: Treatment of Primary Mood Disorders in the Comorbidly Ill
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Bipolar I Disorder
Borderline Personality Disorder
Lead sponsor: University of Pittsburgh
Sponsor class: OTHER
First posted: 2005-09-15
Enrollment: 13
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study will examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

Detailed description: The major aim of this proposal is to examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.

The specific aims are to create a research and supervisory team and to identify potential moderators of treatment response and mediators of outcome over the course of treatment.

Members of the team will meet weekly to begin a treatment development process for enhancing Interpersonal Social Rhythm Therapy (IPSRT) for these patients. Additional assessment measures will be utilized to examine the proposed mediators and moderators of treatment.

Eligibility criteria: Inclusion Criteria:

* Bipolar I Disorder with Comorbid Borderline Personality Disorder, currently manic or depressed

Exclusion Criteria:

* Unstable Medical illness

Primary outcomes:
measure: Hamilton Rating Scale for Depression (HRSD-25)
Secondary outcomes:
measure: Raskin Severity of Depression and Mania Scales
Other outcomes:
Locations:
city: Pittsburgh
country: United States
facility: Western Psychiatric Institute and Clinic
state: Pennsylvania
Study officials:
affiliation: University of Pittsburgh
name: Ellen Frank
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05519761: A Retrospective, Observational, Multicenter Study to Evaluate the Safety and Performance of POLYSITE® and SEESITE® Implantable Ports
Official title: A Retrospective, Observational, Multicenter Study to Evaluate the Safety and Performance of POLYSITE® and SEESITE® Implantable Ports
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Veinous
Chemotherapy
Antibiotics
Antiviral Drugs
Parenteral Nutrition
Blood Transfusion
Blood Derivatives Transfusion
PMCF Study
Lead sponsor: Perouse Medical
Sponsor class: INDUSTRY
Collaborators: name: Eclevar Medtech
First posted: 2022-08-29
Enrollment: 250
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All references of POLYSITE® and SEESITE® implantable ports apply to adult targeted population group.

Only POLYSITE® and SEESITE® implantable ports referenced as 2000 series (micro size) and connected to a 5F catheter apply to paediatric (\>10 kg) targeted population groups.

Brief summary: The purpose of this study is to evaluate performance and safety of POLYSITE® and SEESITE® implantable ports allowing repeated and prolonged access to the venous system for the administration of chemotherapy, antibiotics, antiviral drugs, parenteral nutrition, and for blood transfusion or blood derivatives transfusion.


Eligibility criteria: Inclusion Criteria:

* Adult and paediatric population
* Patient who received the implantation of any POLYSITE® or SEESITE® implantable port referenced in the Annex 1 of the current protocol between 1-JAN-2018 and 31-DEC-2020

Exclusion Criteria:

* Patient who refused the data collection according to GDPR regulation applicable in France
* Patient who received the implantation of another device than those presented in Annex 1 of the current protocol.

Primary outcomes:
measure: Performance : success of the insertion and placement of the implantable port.
timeFrame: Peri-procedure
measure: Associate Performance : correct device insertion assess by Radiological endpoint
timeFrame: Peri-procedure
measure: Associate Performance : correct device insertion assess Clinical endpoint
timeFrame: Peri-procedure
measure: Per-procedure Safety
timeFrame: 30 Days
measure: Associated Safety : rate of complications
timeFrame: 30 days
Secondary outcomes:
measure: Performance : evaluation of the device performance
timeFrame: 5 years
measure: device failure
timeFrame: 5 years
measure: Safety: perioperative time
timeFrame: 5 years
measure: Safety FU period: Device Failure Removal
timeFrame: 5 years
measure: Safety Long Term period: Device Failure Removal
timeFrame: 5 years
measure: Safety Long Term period: complications
timeFrame: 5 years
measure: Emergent Risks
timeFrame: 5 years
Other outcomes:
Locations:
city: Orléans
country: France
facility: CHR d'Orléans
city: Suresnes
country: France
facility: Hopital Foch
city: Villejuif
country: France
facility: IGR
Study officials:
References:
Clinical trial NCT00241761: Epidemiology of Depression and Heart Failure in Aging
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cardiovascular Diseases
Heart Diseases
Heart Failure
Heart Failure, Congestive
Depression
Coronary Disease
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Sponsor class: NIH
First posted: 2005-10-19
Sex: ALL
Maximum age (years): 100
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no

Brief summary: To understand how depression leads to congestive heart failure (CHF) in older adults.

Detailed description: BACKGROUND:

Depression is known to be associated with an increased risk of coronary heart disease (CHD), and with adverse outcomes among older adults with CHD. Recent evidence suggests that depression is also associated with an increased risk of congestive heart failure, and with adverse outcomes among older adults with congestive heart failure. However, the mechanisms by which depression leads to congestive heart failure are not known

DESIGN NARRATIVE:

To determine the mechanisms of association between depression and CHF, the investigators will use an existing cohort of 1024 older adults (mean age 67) with CHD (including 680 with no heart failure and 344 with clinical or subclinical heart failure) who were recruited between September 2000 and December 2002 for "The Heart and Soul Study." The Heart and Soul Study was originally designed to understand the mechanism of association between depression and CHD. Since patients with CHD are at high risk for CHF, this well-characterized cohort will provide a unique opportunity to examine the relation between depression and CHF. At baseline, participants completed a depression interview (Diagnostic Interview Schedule); full exercise treadmill testing with stress echocardiography; 24-hour Holter monitoring for heart rate variability; 24-hour urine collection for cortisol and norepinephrine; venous blood measurements for lipids, platelet reactivity, and C-reactive protein; and an extensive questionnaire. Participants have been followed annually by telephone. The investigators will invite all participants to return for a 5-year examination, and will follow them for an additional 3 years thereafter, to determine (a) the independent association between baseline depression and CHF, and (b) the extent to which 5-vear changes in biological and behavioral factors associated with depression explain the relation between depression and CHF. By identifying the mechanisms that explain the relation between depression and CHF, this study will enable them to target specific areas for improving the treatment of these patients.

Eligibility criteria: No eligibility criteria

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Northern California Institute for Res & Educ
name: Mary Whooley
References:
Clinical trial NCT00293761: A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Open-angle Glaucoma
Ocular Hypertension
Keywords: open-angle
glaucoma
ocular
hypertension
Lead sponsor: Alcon Research
Sponsor class: INDUSTRY
First posted: 2006-02-20
Enrollment: 109
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of the study is to determine whether a glaucoma therapy is safe and effective in treating patients with open-angle glaucoma or ocular hypertension


Eligibility criteria: Inclusion Criteria:

* Adult patients of either sex of any race diagnosed with open-angle glaucoma (with or without pseudoexfoliation or pigment dispersion component) or ocular hypertension.
* Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

* Under age 18.
* Other protocol-defined exclusion criteria may apply.

Primary outcomes:
measure: Mean IOP
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Gross RL, Peace JH, Smith SE, Walters TR, Dubiner HB, Weiss MJ, Ochsner KI. Duration of IOP reduction with travoprost BAK-free solution. J Glaucoma. 2008 Apr-May;17(3):217-22. doi: 10.1097/IJG.0b013e31815a3472.
Clinical trial NCT00662961: Forehead Lift Fixation
Official title: Periosteum Versus Bone for the Fixation of Forehead Lift: A Prospective, Randomized, Controlled, Split-Face Trial.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Forehead
Keywords: Plastic Surgery
Lead sponsor: Federal University of Uberlandia
Sponsor class: OTHER
First posted: 2008-04-21
Enrollment: 12
Sex: ALL
Minimum age (years): 21
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: To compare periosteum versus bone fixation in forehead lift.

Detailed description: Forehead lift method of fixation is variable and lots of different methods have been described with different rates of success.

The comparison of to different techniques in a RCT has not been reported before.

The objective is to compare periosteum versus bone fixation in forehead lift, in a randomized, blinded, controlled, split-face trial.

Eligibility criteria: Inclusion Criteria:

* Eye brow malposition
* Forehead wrinkles

Exclusion Criteria:

* Previous surgery
* Forehead trauma or scar

Primary outcomes:
measure: Eye brow position
timeFrame: 6 months
Secondary outcomes:
measure: Patients' satisfaction
timeFrame: 6 months
measure: Complications
timeFrame: 6 months
Other outcomes:
Locations:
city: Uberlandia
country: Brazil
facility: Federal University of Uberlandia, Department of ENT/H&N
state: MG
Study officials:
affiliation: Federal University of Uberlandia, Department of ENT/H&N
name: Lucas G Patrocinio, MD
role: PRINCIPAL_INVESTIGATOR
References: