Clinical trial NCT05856032: Effects of Acapella With Conventional Chest Physiotherapy Techniques in Post CABG Patients.
Official title: Effects of Using Acapella in Combination With Conventional Chest Physiotherapy Techniques to Improve Pulmonary Functions in Post CABG Patients.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cardiac Procedure Complication
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-05-12
Enrollment: 66
Sex: ALL
Minimum age (years): 45
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To determine the effects of using Acapella as an oscillatory positive expiratory pressure device in combination with conventional chest physiotherapy for secretion removal and revival of pulmonary functions in hospitalized post coronary artery bypass grafting patients.

Detailed description: Acapella is one of the Oscillatory Positive Expiratory Pressure (OPEP) device used in mobilization of peripheral secretions to the central trachea. It consists of a mouth piece and metal strip that is attached to a magnet which oscillates upon exhalation of the patient into the device results in oscillations. This helps in generating positive expiratory pressure (PEP) and oscillations of the magnetic ball assist in mucus collection and expectoration. Pulmonary functions are greatly reduced in patients undergone CABG surgery due to prolong effects of anesthesia and muscle relaxants administered prior to surgery. Ciliary motion along the pathway of pulmonary tract is depressed which results in decrease expectoration capacity, causes mucus retention and reduces pulmonary volumes and capacities. Chest physiotherapy is the treatment option for such patients that is being practiced over years. In recent years certain respiratory aids or devices are also in use to relieve secretion retention along with standard chest physiotherapy techniques.

The purpose of this study is to find the effects of using Acapella as an OPEP device along with conventional chest physiotherapy techniques in post-CABG surgery patients to relieve mucus retention and improving pulmonary functions post-surgery.

Eligibility criteria: Inclusion Criteria:

* Patients of both genders within age range of 45-65 years
* Elective CABG surgery patients
* Patients undergoing Phase 1 cardiac rehabilitation post CABG
* Patients who are vitally stable post operatively

Exclusion Criteria:

* Patient having prolong intubation period post-operatively
* Patients having long term arrythmias prior to surgery
* Patients having an implanted pacemaker
* Patients having uncontrolled diabetes, sepsis or any metabolic condition
* Patients with impaired cognition.

Primary outcomes:
measure: Change in Forced Expiratory Volume in 1 second
timeFrame: pre-operative day 1 and post-operative day 6 of CABG surgery
measure: Change in Forced Vital Capacity
timeFrame: pre-operative day 1 and post-operative day 6 of CABG surgery
measure: Ratio of Forced Expiratory Volume in 1 second and Forced Vital Capacity
timeFrame: pre-operative day 1 and post-operative day 6 of CABG surgery
Secondary outcomes:
measure: Borg dyspnoea scale
timeFrame: 6th post-operative day after CABG surgery
measure: Amount of secretions expectorated
timeFrame: 6th post-operative day after CABG surgery
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Armed Forces Institute of Cardiology
state: Punjab
Study officials:
affiliation: Riphah International University
name: Malik Muhammad Ali Awan, MSPT
role: PRINCIPAL_INVESTIGATOR
References: