Clinical trial NCT06252688: Conceptualisation of a Network Approach to Complete the Classification of Eating Disorders With the Aim of Better Personalising Their Management
Official title: Conceptualisation of a Network Approach to Complete the Classification of Eating Disorders With the Aim of Better Personalising Their Management
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Eating Disorders
Eating Disorder Binge
Keywords: Anorexia nervosa
Bulimia
Binge eating disorders
Neuropsychology
Neurocognitiond
Daily functioning
Lead sponsor: University Hospital, Montpellier
Sponsor class: OTHER
First posted: 2024-02-12
Enrollment: 840
Sex: ALL
Minimum age (years): 15
Maximum age (years): 65
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: Eating disorders (EDBs) are mental disorders with a great impact on the lives of individuals as well as a great cost imposed on society. The treatments currently available rely on different forms of psychotherapies with an unsatisfactory response rate as well as a considerable relapse rate . One of the reasons underlying the low success of available therapeutic modalities would be the heterogeneity of the clinical presentation of EDs, making their classification and the personalization of their treatment more difficult.The investigators hypothesize that a secondarily dimensional classification approach (respecting the categorical classification currently in use) of EDs based on the different dimensions disturbed in these disorders as well as in their comorbidities, would better represent their nosographic reality, which could provide patients with more personalized and potentially more effective care.

Detailed description: Detailed Description:

The investigators will recruit a total of 840 patients with an eating disorder in the university hospital of Montpellier.

- Participation consists of a one-day visit with a multidisciplinary assessment. No action is specific to research except the biological collection for the constitution of a genetic bank. This is the usual management of patients with eating disorders addressed to our department.

Eligibility criteria: Inclusion Criteria:

* Patient with an eating disorder according to DSM-V criteria
* Patient aged from 15 to 65 years
* Patient who performs the day-hospital evaluation
* Patient affiliated to a French social security system
* Patient able to understand the nature, the aim and the methodology of the study
* For minor one of the legal guardians gave his consent

Exclusion Criteria:

* Patient in an unstable somatic state (eg severe metabolic disorder making impossible or unreliable neuropsychological assessments)
* Patient's refusal to participate
* Patient protected by law (guardianship or curatorship)\*
* Pregnant or nursing women. A dosage of βHCG will be performed to ensure the absence of pregnancy

Primary outcomes:
measure: Eating Disorders Inventory (EDI-2)
timeFrame: Baseline
measure: Eating Disorder Examination Questionnaire (EDE-Q)
timeFrame: Baseline
Secondary outcomes:
measure: Symptomatic dimensions of Eating Disorder Examination Questionnaire (EDEQ)
timeFrame: baseline
measure: Body Shape Questionnaire (BSAQ-34)
timeFrame: baseline
measure: Yale Food Addiction Scale (YFAS)
timeFrame: baseline
measure: Sociocultural Attitudes Towards Appearance Scale (SATAQ-4)
timeFrame: baseline
measure: Female drive for muscularity scale (FDMS)
timeFrame: baseline
measure: exercice and Eating disorders questionnaire (EED)
timeFrame: baseline
measure: Childhood Trauma Questionnaire (CTQ)
timeFrame: baseline
measure: depression scale (PQ-9)
timeFrame: baseline
measure: The anxiety scale (GAD-7)
timeFrame: baseline
measure: The insomnia severity index (ISI)
timeFrame: baseline
measure: The disgust propensity and sensitivity scale (DPSS-R)
timeFrame: Baseline
measure: The emotional regulation scale (DERS-F)
timeFrame: baseline
measure: The Sheehan Global Functioning Scale (SDS)
timeFrame: baseline
measure: Detail and flexibility questionnaire (Dflex)
timeFrame: baseline
measure: Rey's figure
timeFrame: baseline
measure: d2 attention test
timeFrame: Baseline
measure: Wisconsin test (WCST-64)
timeFrame: Baseline
measure: Delay discounting task (DDT)
timeFrame: Baseline
measure: Mini International Neuropsychiatric Interview
timeFrame: Baseline
measure: The relationship between BMI and the biological parameters of the blood test
timeFrame: Baseline
measure: The relationship between disease duration and the biological parameters of the blood test
timeFrame: Baseline
measure: The relationship between BMI and calorimetry data
timeFrame: Baseline
measure: The relationship between disease duration and calorimetry data
timeFrame: Baseline
measure: The relationship between BMI of TCA and bone densitometry data
timeFrame: Baseline
measure: The relationship between BMI and impedancemetry data
timeFrame: Baseline
measure: The relationship between disease duration and impedancemetry data
timeFrame: Baseline
Other outcomes:
Locations:
Study officials:
References: