Clinical trial NCT00096772: Collection of Blood Samples From HIV Infected People
Official title: Collection and Use of Blood For Genetic and Other Related Analyses (The GENOMICS Protocol)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: HIV Infections
Keywords: Genetic Testing
Genomics
Human Genetic Factors
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Sponsor class: NIH
First posted: 2004-11-16
Enrollment: 2502
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Study participants will be selected from those who have given informed consent for participation in a qualifying CPCRA clinical trial.

Brief summary: The purpose of this study is to collect blood samples from HIV infected individuals for use in future genetic studies.

Detailed description: Genetic differences among people with HIV may account for differences in disease progression and response to antiretroviral therapy. The Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA) was created to conduct studies in HIV infected communities and particularly in people of color, women, and injection drug users. This study will collect whole blood samples from HIV infected individuals. The samples will be used in future CPCRA studies comparing human genetic factors with clinical data from other CPCRA studies.

Eligibility criteria: Inclusion Criteria:

* Presently participating, previously participated in, or has given informed consent for participation in a qualifying CPCRA clinical trial
* Signed informed consent

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Mill Valley
country: United States
facility: Dr. M. Estes Med. Practice CRS
state: California
city: Oakland
country: United States
facility: Dr. Robert Scott Med. Practice CRS
state: California
city: Oakland
country: United States
facility: East Bay AIDS Ctr. CRS
state: California
city: San Francisco
country: United States
facility: Dr. Shawn Hassler Med. Practice CRS
state: California
city: San Francisco
country: United States
facility: Positive Health Program Clinic (San Francisco Gen. Hosp.) CRS
state: California
city: San Francisco
country: United States
facility: Dr. Virginia Cafaro Med. Practice CRS
state: California
city: San Francisco
country: United States
facility: Dr. William Owen Med. Practice CRS
state: California
city: San Francisco
country: United States
facility: Castro-Mission Health Ctr. CRS
state: California
city: San Francisco
country: United States
facility: St. Mary's Med. Ctr. of San Francisco CRS
state: California
city: San Francisco
country: United States
facility: San Francisco VAMC, Infectious Diseases Clinic CRS
state: California
city: San Francisco
country: United States
facility: UCSF PHP, Gen. Internal Medicine Practice CRS
state: California
city: Boulder
country: United States
facility: Beacon Clinic at Boulder CRS
state: Colorado
city: Denver
country: United States
facility: Denver Infectious Diseases Consultants CRS
state: Colorado
city: Denver
country: United States
facility: Kaiser Permanente of Denver CRS
state: Colorado
city: Denver
country: United States
facility: Univ. of Colorado Health Science Ctr. CRS
state: Colorado
city: Denver
country: United States
facility: Denver Public Health CRS - INSIGHT
state: Colorado
city: Denver
country: United States
facility: Denver Public Health CRS
state: Colorado
city: Denver
country: United States
facility: Eastside Family Health Ctr. CRS
state: Colorado
city: Denver
country: United States
facility: APEX Family Medicine CRS
state: Colorado
city: Denver
country: United States
facility: South Denver Infectious Diseases Specialists, Accord Med. Ctr. CRS
state: Colorado
city: Wheat Ridge
country: United States
facility: Western Infectious Disease Consultants CRS
state: Colorado
city: New Haven
country: United States
facility: Yale Univ. School of Medicine, NE ProACT - New Haven CRS
state: Connecticut
city: Georgetown
country: United States
facility: Georgetown Wellness Clinic
state: Delaware
city: Wilmington
country: United States
facility: Christiana Care Health Services HIV Program CRS
state: Delaware
city: Washington
country: United States
facility: Washington DC VAMC, Washington Regional AIDS Program, Infectious Diseases CRS
state: District of Columbia
city: Chicago
country: United States
facility: Klein & Slotten Medical Associates CRS
state: Illinois
city: Chicago
country: United States
facility: Univ. of Illinois Family Ctr. for Infectious Disease CRS
state: Illinois
city: Chicago
country: United States
facility: Lakeshore Infectious Disease Associates CRS
state: Illinois
city: Chicago
country: United States
facility: North Side Family Medicine CRS
state: Illinois
city: Baton Rouge
country: United States
facility: Earl K. Long Med. Ctr., LSU - Mid City EIC Clinic CRS
state: Louisiana
city: Baton Rouge
country: United States
facility: James Osterberger, MD (Private Med. Practice) CRS
state: Louisiana
city: New Orleans
country: United States
facility: Med. Ctr. of Louisiana at New Orleans, HIV Outpatient Clinics CRS
state: Louisiana
city: New Orleans
country: United States
facility: Tulane University Health Sciences Center, Louisiana Community AIDS Research Program(LaCARP) CRS
state: Louisiana
city: New Orleans
country: United States
facility: New Orleans VAMC CRS
state: Louisiana
city: Boston
country: United States
facility: CRI-Boston CRS
state: Massachusetts
city: Springfield
country: United States
facility: CRI-Springfield CRS
state: Massachusetts
city: Detroit
country: United States
facility: Harper Hosp., Detroit CRS
state: Michigan
city: Detroit
country: United States
facility: Wayne State Univ. CRS
state: Michigan
city: Detroit
country: United States
facility: Wayne State Univ. INSIGHT CRS
state: Michigan
city: Detroit
country: United States
facility: Henry Ford Hosp. CRS
state: Michigan
city: Detroit
country: United States
facility: Henry Ford Hosp., Div. of Infectious Disease INSIGHT CRS
state: Michigan
city: Detroit
country: United States
facility: Detroit Community Health Connection, Inc. CRS
state: Michigan
city: Jackson
country: United States
facility: Univ. of Mississippi Med. Ctr., Div. of Infectious Diseases CRS
state: Michigan
city: Lansing
country: United States
facility: Michigan State Univ., Infectious Disease Clinic CRS
state: Michigan
city: Camden
country: United States
facility: Cooper Hospital/Univ. Med. Ctr., The Cooper Early Intervention Program (EIP) CRS
state: New Jersey
city: Camden
country: United States
facility: Cooper Univ. Hosp. CRS
state: New Jersey
city: Hillsborough
country: United States
facility: ID Care Inc. - Hillsborough CRS
state: New Jersey
city: Neptune
country: United States
facility: Jersey Shore Univ. Med. Ctr. CRS
state: New Jersey
city: Newark
country: United States
facility: Cathedral Healthcare System, St. Michael's Med. Ctr. CRS
state: New Jersey
city: Newark
country: United States
facility: New Jersey Community Research Initiative, Jeffrey Bomser Clinic CRS
state: New Jersey
city: Paterson
country: United States
facility: St. Joseph's Hosp. & Med. Ctr. of New Jersey CRS
state: New Jersey
city: Paterson
country: United States
facility: St. Joseph's Hosp. & Med. Ctr. of New Jersey
state: New Jersey
city: Perth Amboy
country: United States
facility: Raritan Bay Med. Ctr., Perth Amboy Division CRS
state: New Jersey
city: Randolph
country: United States
facility: ID Care - Randolph CRS
state: New Jersey
city: Union
country: United States
facility: Infectious Disease Specialists of N.J., North Jersey Community Research Initiative CRS
state: New Jersey
city: Voorhees
country: United States
facility: The Early Intervention Program at Kennedy Hosp. CRS
state: New Jersey
city: Bronx
country: United States
facility: Bronx- Lebanon Hospital Center Clinical Research Site (BLHC CRS)
state: New York
city: Bronx
country: United States
facility: Bronx-Lebanon Hosp. Ctr. CRS
state: New York
city: Bronx
country: United States
facility: Montefiore Med. Ctr., AIDS Ctr. CRS
state: New York
city: New York
country: United States
facility: St. Vincent Hosp. & Med. Ctr. CRS
state: New York
city: New York
country: United States
facility: Harlem Hospital Ctr./Columbia University CRS (Gordin CTU)
state: New York
city: New York
country: United States
facility: Harlem Hosp. Ctr., Outpatient Clinics (New York) CRS
state: New York
city: Portland
country: United States
facility: Multnomah County Health Dept., HIV Health Services Ctr. CRS
state: Oregon
city: Portland
country: United States
facility: Legacy Clinic Good Samaritan CRS
state: Oregon
city: Portland
country: United States
facility: The Research & Education Group-Portland CRS
state: Oregon
city: Portland
country: United States
facility: Providence Portland Med. Ctr., Ambulatory Care and Education Ctr. CRS
state: Oregon
city: Portland
country: United States
facility: Kaiser Immune Deficiency Clinic of Portland CRS
state: Oregon
city: Portland
country: United States
facility: Legacy Clinic Emanuel CRS
state: Oregon
city: Portland
country: United States
facility: Legacy Clinic Northeast CRS
state: Oregon
city: Portland
country: United States
facility: Oregon Health & Sciences Univ. Internal Medicine (L-475) CRS
state: Oregon
city: Philadelphia
country: United States
facility: Temple Univ. School of Medicine CRS
state: Pennsylvania
city: Houston
country: United States
facility: Baylor College of Medicine, Thomas St. Clinic CRS
state: Texas
city: Houston
country: United States
facility: Houston AIDS Research Team CRS
state: Texas
city: Houston
country: United States
facility: Michael E. DeBakey VAMC CRS
state: Texas
city: Houston
country: United States
facility: Thomas Street Clinic CRS
state: Texas
city: Fredericksburg
country: United States
facility: MediCorp, Infectious Disease Associates CRS
state: Virginia
city: Petersburg
country: United States
facility: Petersburg Health Care Alliance CRS
state: Virginia
city: Richmond
country: United States
facility: Vernon Harris East End Community Health Ctr. CRS
state: Virginia
city: Richmond
country: United States
facility: CrossOver Health Ctr. CRS
state: Virginia
city: Richmond
country: United States
facility: South Richmond Health Care Ctr. CRS
state: Virginia
city: Richmond
country: United States
facility: Hunter Holmes McGuire VAMC CRS
state: Virginia
city: Richmond
country: United States
facility: VCU Health Systems, Infectious Disease Clinic CRS
state: Virginia
city: Richmond
country: United States
facility: Virginia Commonwealth Univ. Medical Ctr. CRS
state: Virginia
Study officials:
affiliation: AIDS Research Alliance Chicago (ARAC), University of Illinois at Chicago
name: Jonathan Uy, MD
role: STUDY_CHAIR
References:
citation: Anastassopoulou CG, Kostrikis LG. The impact of human allelic variation on HIV-1 disease. Curr HIV Res. 2003 Apr;1(2):185-203. doi: 10.2174/1570162033485311.
citation: O'Brien SJ, Nelson GW. Human genes that limit AIDS. Nat Genet. 2004 Jun;36(6):565-74. doi: 10.1038/ng1369.
citation: Telenti A. The genetic cohorts: facing the new challenges in infectious diseases. The HIV model. Enferm Infecc Microbiol Clin. 2004 Jun-Jul;22(6):337-41. doi: 10.1016/s0213-005x(04)73106-7.