Clinical trial NCT05702840: EXerCise wEight Loss
Official title: The Effects of a Home-based Resistance Training Programme on Body Composition and Muscle Function During Weight Loss in People With Overweight or Obesity: a Randomised Controlled Pilot Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Overweight and Obesity
Lead sponsor: University of Glasgow
Sponsor class: OTHER
First posted: 2023-01-27
Enrollment: 48
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomised controlled pilot trial with two groups, resistance exercise + weight loss group and weight loss only group.
Primary purpose: BASIC_SCIENCE

Brief summary: The overall aim of this study is to investigate the effects of home-based resistance exercise programme on changes in body composition and strength during weight loss, in people living with obesity or overweight.


Eligibility criteria: Inclusion Criteria:

* Obesity or overweight (BMI ≥ 25kg/m2).
* Passing the Physical Activity Readiness Questionnaire (PAR-q+)

Exclusion Criteria:

* Currently take part in more than 1.5 hours of structured exercise per week.
* Having recently (\<6 months) taken part in any resistance exercise training, taking any medications known to affect weight loss.
* Actively engaged in a weight loss programme, having lost more than 2kg weight in the last 6 months.
* Any other reason which would limit ability to perform the exercises and outcome measurements safely.

Primary outcomes:
measure: Change in whole body lean mass
timeFrame: Change from baseline to 12 weeks
Secondary outcomes:
measure: Change in whole body fat mass
timeFrame: Change from baseline to 12 weeks
measure: Change in body mass
timeFrame: Change from baseline to 12 weeks
measure: Change in vastus lateralis muscle thickness
timeFrame: Change from baseline to 12 weeks
measure: Change in knee extensor maximal isometric torque
timeFrame: Change from baseline to 12 weeks
measure: Change in grip strength
timeFrame: Change from baseline to 12 weeks
measure: Change in functional physical abilities
timeFrame: Change from baseline to 12 weeks
Other outcomes:
Locations:
city: Glasgow
country: United Kingdom
facility: Stuart Robert Gray
Study officials:
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