Clinical trial NCT02844985: A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction
Official title: Genetic Markers in Sexual Addiction
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Sexual Addiction
Keywords: Sexual Addiction
Genomics
Personality
Polymorphism
Lead sponsor: American Foundation for Addiction Research
Sponsor class: OTHER
Collaborators: name: University of Alberta
name: University of Southern Mississippi
First posted: 2016-07-26
Enrollment: 2000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Sexual Addict Group: individuals undergoing treatment for sexual addiction.

Control Group: individuals from general community who have no history of addiction or psychopathology

Brief summary: The study is intended to identify gene polymorphisms significantly associated with specific behavioral- and preoccupation-typologies of sexual addiction, and to identify additional potential genetic markers of sexual addiction. Research subjects with sexual addiction will be identified from the out-patient and in-patient populations of the investigative sites. Research subjects in the Control Group will be identified from the general population and from the student body of selected colleges. Approximately 1100 subjects will be enrolled in the study. Anticipating 10% drop-out, this is intended to generate a population of approximately 500 men and women clinically diagnosed with sexual addiction, and approximately 500 healthy men and women who do not meet diagnostic criteria for sexual addiction nor have psychopathology who will serve as the control population.


Eligibility criteria: Inclusion Criteria:

* Sexual Addict Group

Age \>= 18 years

Participating in sexual addiction treatment program

Sexual Addiction Screening Test--Revised (SAST-R) score \>= 11

Meets at least 3 diagnostic criteria for sexual addiction

* Control Group

Age \>= 18 years

SAST-R score \< 6

Exclusion Criteria:

* Sexual Addiction Group

Serious mental illness

Significant cognitive impairment

* Control Group

History of addiction

Current or previous Diagnostic and Statistical Manual (DSM-5) diagnosis

Serious mental illness

Significant cognitive impairment

Primary outcomes:
measure: Gene polymorphisms identified through polymerase chain reaction using fluorescent primers and restriction fragment length polymorphism analysis
timeFrame: Assessed at Enrollment
Secondary outcomes:
Other outcomes:
Locations:
city: Scottsdale
country: United States
facility: Psychological Counseling Services
state: Arizona
city: Wickenburg
country: United States
facility: Gentle Path at The Meadows
state: Arizona
city: Los Angeles
country: United States
facility: Center for Healthy Sex
state: California
city: Los Angeles
country: United States
facility: Triune Therapy Group
state: California
city: Hattiesburg
country: United States
facility: Pine Grove Behavioral Health and Addiction Services
state: Mississippi
city: Rochester
country: United States
facility: Kavod Center
state: New York
city: Houston
country: United States
facility: Center for Healthy Sexuality
state: Texas
city: Bellevue
country: United States
facility: Seattle Christian Counseling
state: Washington
Study officials:
References: