Clinical trial NCT04195152: Lingual Nerve Injury in Patients With Difficult Intubation
Official title: Investigation of the Incidence of Lingual Nerve Injury and Related Factors in Patients With Difficult Intubation
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Difficult Intubation
Lingual Nerve Injuries
Keywords: Difficult intubation
Lingual nerve injury
Body mass index
Lead sponsor: Istanbul Medeniyet University
Sponsor class: OTHER
First posted: 2019-12-11
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All adult patients undergo general anesthesia who have difficulty in intubation will be included in the study.

Brief summary: The aim of this study is to investigate the incidence of lingual nerve injury and related factors in difficult intubation cases.

Demographic data of difficult intubation cases and body mass indices, thyromental and sternomental distances, mallampati classification, neck circumference, maximum mouth opening be recorded.Numbness of the tongue and metallic taste will be questioned

Detailed description: The lingual nerve is the anterior descending branch of the posterior trunk of the mandibular division of the trigeminal nerve.

Lingual nerve injury is a recognised complication of orotracheal intubation and has been associated with forceful laryngoscopy.

Although left-sided neuropraxia has been reported, right-sided lesions are thought to be more common because the standard Macintosh laryngoscope exerts pressure on the right side of the tongue.

Lingual nerve injury following orotracheal intubation was first described in 1971 by Teichner who reported a right-sided neuropraxia which was attributed to direct pressure from the laryngoscope.

Eligibility criteria: Inclusion Criteria:

All adult patients undergo general anesthesia who have difficulty in intubation will be included in the study. The same number of patients without intubation difficulties will be included in the study as a control group.

Exclusion Criteria:

1. Patients who are not intubated under general anesthesia
2. Patients undergoing regional anesthesia or peripheral nerve block
3. Patients with laryngeal mask placed will not be included in the study.

Primary outcomes:
measure: The incidence of lingual nerve injury
timeFrame: 1 year
Secondary outcomes:
measure: Rate of emergency tracheotomy
timeFrame: 1 year
measure: Incidence of cardiovascular complications
timeFrame: 1 year
measure: Percentage of patients with teeth injuries
timeFrame: 1 year
measure: Percentage of patients with oral mucosa injuries
timeFrame: 1 year
measure: Percentage of patients with temporary difficulty in swallowing
timeFrame: 1 year
measure: Percentage of patients with temporary difficulty in breathing
timeFrame: 1 year
measure: Incidence of inability to taste
timeFrame: 1 year
measure: Incidence of numbness in the tongue
timeFrame: 1 year
measure: Percentage of patients with metallic taste in the tongue
timeFrame: 1 year
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul MU Goztepe Training and Research Hospital
Study officials:
References: