Clinical trial NCT06759532: Impact of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance on Prognosis for ST-segment Elevation Myocardial Infarction
Official title: Prognostic Role of Persistent Microvascular Obstruction by Cardiac Magnetic Resonance for ST-segment Elevation Myocardial Infarction
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: ST Elevation (STEMI) Myocardial Infarction
Keywords: Microvascular occlusion;
ST-segment elevation myocardial infarction
Prognosis
Lead sponsor: Chinese PLA General Hospital
Sponsor class: OTHER
First posted: 2025-01-06
Enrollment: 344
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The patients in this study were diagnosis as STEMI, and were plan to undergo primary percutaneous coronary intervention and were plan to underwent cardiac magnetic resonance at 7 days and 6 months after primary percutaneous coronary intervention . The patients were divided into three groups according to the presence of absence of MVO at the first cardiac magnetic resonance and second cardiac magnetic resonance.

Brief summary: The aims of the study were to evaluate the predictive value of persistent microvascular obstruction (MVO) by cardiac magnetic resonance for main adverse cardiac events in ST-segment elevation myocardial infarction patients.

MVO in the acute phase of myocardial infarction has been considered to be strong predictor of a poor prognosis. We plan to explore the relationship between persistent MVO and the long-term prognosis of patients with STEMI. We made hypothesis that patients with persistent MVO have a poor prognosis.


Eligibility criteria: Inclusion Criteria:

* ST-segment elevation myocardial infarction undewent primary percutaneous coronary intervention

Exclusion Criteria:

* contraindications for cardiac magnetic resonance
* severe heart failure
* previous myocardial infarction.

Primary outcomes:
measure: Main aderverse cardiac events
timeFrame: 5 years after myocardiac infarction
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Chinese PLA general hospital
state: Beijing
Study officials:
References:
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