Clinical trial NCT03049436: Adapted Physical Activity in a Chemotherapy Ambulatory Care Unit: Feasibility and Impact on Fatigue, Anxiety and Depression in Cancer Patients
Official title: Adapted Physical Activity in a Chemotherapy Ambulatory Care Unit: Feasibility and Impact on Fatigue, Anxiety and Depression in Cancer Patients
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Adapted Physical Activity and Cancer
Keywords: Physical activity
cancer
chemotherapy
daily care unit
Lead sponsor: CHU de Reims
Sponsor class: OTHER
First posted: 2017-02-10
Enrollment: 250
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients undergoing chemotherapy or targeted therapy at UMA-CH ambulatory care service of Reims, CHU, for a digestive, lung, hematological or dermatological cancers, of any stage, between February 2017 and August 2017

Brief summary: Physical activity has demonstrated efficacy in cancer prevention and improves quality of life and outcome in cancer survivors. Patients undergoing chemotherapy, especially those with advanced disease, may have symptoms leading to inactivity. Adapted physical activity (APA) among those patients could improve their tolerance to the treatment, and thereby their quality of life. APA could be beneficial to patients with curable disease as well as patients undergoing palliative chemotherapy. Some studies suggest that fighting against loss of muscle mass could lead to a survival benefit. However, APA is not established in daily practice and has not yet been evaluated in a chemotherapy ambulatory care unit.

Primary aim of the study is to assess feasibility of an APA program in a chemotherapy ambulatory care unit of digestive, lung, hematological and dermatological cancers Secondary aim is to measure the impact of an APA program on fatigue, anxiety, depression and handgrip strength in patients beginning chemotherapy or targeted therapy for a digestive, lung, hematological or dermatological cancer, of any stage.

Detailed description: Assess feasibility of an APA program in a chemotherapy ambulatory care unit of digestive, lung, hematological, and dermatological cancers Measure the impact of an APA program on fatigue, anxiety, depression, handgrip strength

Eligibility criteria: Inclusion Criteria:

* Patients beginning chemotherapy or targeted therapy at UMA-CH ambulatory care unit of Reims, CHU, for a digestive, lung, hematological or dermatological cancer, of any stage
* Patients who agree to participate to the study
* Major patient

Exclusion Criteria:

* Patient with previous chemotherapy or targeted therapy in the UMA-CH unit
* Patient under law protection
* Minor patient
* Patient with neurological defect preventing from any physical activity

Primary outcomes:
measure: Feasibility of APA program
timeFrame: Day 0
Secondary outcomes:
measure: fatigue
timeFrame: Month 3
measure: Anxiety
timeFrame: Month 3
measure: Fatigue
timeFrame: Month 6
measure: Anxiety
timeFrame: Month 6
measure: handgrip strength
timeFrame: Month 3
measure: handgrip strength
timeFrame: Month 6
Other outcomes:
Locations:
city: Reims
country: France
facility: Chu de Reims
Study officials:
References: