Clinical trial NCT05660629: Mulligan Mobilization in Rheumatoid Hand
Official title: Comparison of the Effects of Exercise and Protective Approach in the Rheumatoid Hand and Joint Mobilization Applications on Pain, Functional Status and Quality of Life
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Rheumatoid Arthritis
Keywords: Mulligan Mobilization
Hand Rheumatoid Arthritis
Lead sponsor: Kirsehir Ahi Evran Universitesi
Sponsor class: OTHER
First posted: 2022-12-21
Enrollment: 21
Sex: ALL
Minimum age (years): 30
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this randomized-controlled study is to learn about the effectiveness of the Mulligan mobilization in rheumatoid hands. The main question it aims to answer are:

-Does mulligan mobilization reduce effusion in wrist joints with rheumatoid arthritis? Participants will take Mulligan mobilization application and active ROM exercises for their hands. Researcher will compare treatments group ith sham mobilization.

Detailed description: Rheumatoid arthritis (RA) is a systemic disease that can lead to chronic pain, bone and soft tissue damage, and disability retirement. Alleviating pain and maintaining joint range of motion in RA are important for reducing disability. Joint mobilizations are manual therapy techniques used to increase range of motion and reduce pain. The aim of this study is to investigate the effects of rheumatoid hand exercise and protective approach and joint mobilization applications on pain, functional status and quality of life.

Eligibility criteria: Inclusion Criteria:

* Having been diagnosed with RAS according to ACR and EULAR criteria,
* Being under the control of a physiatrist for at least 1 year,
* Have not had any upper extremity surgery in the last 6 months
* Have the cognitive capacity to understand commands,
* Not to be involved in any other rehabilitation program or study,

Exclusion Criteria:

* Presence of soft tissue injury and chronic bone damage in the hand,
* Presence of acute inflammation in any joint in the previous week,
* Presence of a degenerative or non-degenerative neurological condition that causes a change in pain perception,

Primary outcomes:
measure: Joint activity
timeFrame: 6 weeks
measure: Amount of hypertrophia and effusion in wrist joints
timeFrame: 6 weeks
measure: Distance in wrist joints
timeFrame: 6 weeks
measure: DAS-28
timeFrame: 6 weeks
Secondary outcomes:
measure: Determining the state of pain after treatment
timeFrame: 6 weeks
measure: Grip force
timeFrame: 6 weeks
measure: Range of Motion
timeFrame: 6 weeks
measure: Post-treatment status of disease-related quality of life
timeFrame: 6 weeks
measure: Physical, social, and emotional well-being in RA
timeFrame: 6 weeks
Other outcomes:
Locations:
city: Kırşehir
country: Turkey
facility: Ahi Evran University
Study officials:
affiliation: Kirsehir Ahi Evran Universitesi
name: Figen TUNCAY, Professor
role: STUDY_DIRECTOR
References:
citation: Levitsky A, Kisten Y, Lind S, Nordstrom P, Hultholm H, Lyander J, Hammelin V, Gentline C, Giannakou I, Faustini F, Skillgate E, van Vollenhoven R, Sundberg T. Joint Mobilization of the Hands of Patients With Rheumatoid Arthritis: Results From an Assessor-Blinded, Randomized Crossover Trial. J Manipulative Physiol Ther. 2019 Jan;42(1):34-46. doi: 10.1016/j.jmpt.2018.04.007. Epub 2019 Mar 14.
citation: Villafane JH, Cleland JA, Fernandez-de-Las-Penas C. Bilateral sensory effects of unilateral passive accessory mobilization in patients with thumb carpometacarpal osteoarthritis. J Manipulative Physiol Ther. 2013 May;36(4):232-7. doi: 10.1016/j.jmpt.2013.05.008. Epub 2013 May 27.
citation: Ozcelep OF, Ustun I, Algun ZC. Effect of task-oriented training on pain, functionality, and quality of life in rheumatoid arthritis. Turk J Phys Med Rehabil. 2022 Mar 1;68(1):76-83. doi: 10.5606/tftrd.2022.6666. eCollection 2022 Mar.