Clinical trial NCT04787146: File Analysis of Falling Patients: Are Drugs Frequently Involved
Official title: File Analysis of Falling Patients: Are Drugs Frequently Involved
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Fall Patients
Keywords: Drugs
Lead sponsor: Fondation Hôpital Saint-Joseph
Sponsor class: OTHER
First posted: 2021-03-08
Enrollment: 52
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: From Monday to Friday, the study will be offered to patients selected consecutively and who have fallen within the previous 24 hours (between 7.55 a.m. the day before and 7.55 a.m. the next day).

Brief summary: The damage caused by patient falls is a major public health problem, due to the large and growing number of people concerned, the potentially serious consequences but also the financial cost generated by their care.

These consequences can be physical as well as psychological. Fractures and pain are the first consequences that come to mind, but many others should be mentioned: post-fall syndrome, loss of autonomy or even entering an institution, fear of falling, loss of confidence in itself.

Detailed description: During 2018, 285 reports of falls were counted within the Paris Saint-Joseph Hospital Group (GhPSJ). Reducing these falls is one of the institutional goals. A dedicated working group has been created to put in place preventive and corrective measures.

These falls can be caused by many factors to the patient:

1. Intrinsic:

   * History of a fall,
   * pathologies (Parkinson's or Alzheimer's disease),
   * hearing and visual disturbances,
   * urinary incontinence.
2. extrinsic:

   * Unsuitable shoes
   * unsuitable habitat,
   * slippery floors (eg bathroom).

Among the intrinsic factors, polypharmacy is also found. It has been established that certain drug classes are at risk of falling, in particular psychotropic drugs (benzodiazepines, hypnotics, anxiolytics, antidepressants, neuroleptics) which promote sedation and dizziness, hypoglycemic drugs which cause hypoglycaemia in diabetic patients on -treated or antihypertensive drugs causing hypotension.

It is now clearly established that drug adherence to treatment is poor in cities, giving rise to omissions but also sometimes to overconsumption of certain drugs, including psychotropic drugs.

Eligibility criteria: Inclusion Criteria:

* Major patient
* French-speaking patient
* Patient hospitalized within the Paris Saint-Joseph Hospital Group
* Patient who fell during hospitalization and for whom a fall report has been completed

Exclusion Criteria:

* Patients in the process of therapeutic limitation
* Patient under guardianship or curatorship
* Patient deprived of liberty
* Patient objecting to participation in the study
* Patient under legal protection

Primary outcomes:
measure: To assess the prevalence of falls associated with one or more risk factors for drug iatrogenism within the Paris Saint-Joseph Hospital Group.
timeFrame: 1 week
Secondary outcomes:
measure: List the drug treatments at risk taken by patients who fall
timeFrame: 1 week
measure: Evaluate the relevance of drug prescriptions in patients who fall
timeFrame: 1 week
measure: Evaluate the overall compliance of falling patients
timeFrame: 1 week
Other outcomes:
Locations:
city: Paris
country: France
facility: Groupe Hospitalier Paris Saint-Joseph
state: Ile De France
Study officials:
affiliation: Fondation Hôpital Saint-Joseph
name: Elodie MENAGE
role: PRINCIPAL_INVESTIGATOR
References: