Clinical trial NCT03071692: Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)
Official title: Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: PHASE3
Conditions: Type2 Diabetes
Dyslipidemia
Lead sponsor: Kowa Research Institute, Inc.
Sponsor class: INDUSTRY
Collaborators: name: Brigham and Women's Hospital
First posted: 2017-03-07
Enrollment: 10544
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The primary objective of the study is to determine whether pemafibrate administered twice daily will delay the time to first occurrence of any component of the clinical composite endpoint of:

* nonfatal Myocardial Infarction (MI)
* nonfatal ischemic stroke
* coronary revascularization; or
* Cardio Vascular (CV) death.

Detailed description: A multi-regional clinical trial with participating sites in the following countries. India is being conducted under a previous protocol version due to regulatory requirements.

* Argentina
* Brazil
* Bulgaria
* Canada
* Colombia
* Czech Republic
* Denmark
* France
* Germany
* Hungary
* India
* Israel
* Japan
* Mexico
* Netherlands
* Poland
* Romania
* Russian Federation
* Slovakia
* South Africa
* Spain
* Ukraine
* United Kingdom
* United States

Eligibility criteria: Inclusion Criteria:

1. Fasting TG ≥ 200 mg/dL (2.26 mmol/L) and \< 500 mg/dL (5.65 mmol/L) at Visit 1 (Screening/Enrollment Visit) or Visit 1.1 (Retest)
2. HDL-C ≤ 40 mg/dL (1.03 mmol/L) at Visit 1 (Screening/Enrollment Visit) or Visit 1.1 (Retest)
3. Type 2 diabetes of longer than 12 weeks duration documented in medical records, for example: local laboratory evidence through medical record review of elevated HbA1c (≥ 6.5% \[48 mmol/mol\]), elevated plasma glucose (fasting ≥ 126 mg/dL \[7.0 mmol/L\], 2-hour ≥ 200 mg/dL \[11.1 mmol/L\] during oral glucose tolerance testing, or random value ≥ 200 mg/dL with classic symptoms, or currently taking medication for treatment of diabetes; AND either

   1. Age ≥ 50 years if male or ≥ 55 years if female (primary prevention cohort); OR
   2. Age ≥ 18 years and established systemic atherosclerosis (secondary prevention cohort), defined as any 1 of the following:

      * i. Prior MI or ischemic (non-hemorrhagic) stroke
      * ii. Coronary angiographic lesion of ≥ 60% stenosis in a major epicardial vessel or ≥ 50% left main stenosis
      * iii. Asymptomatic carotid disease with ≥ 70% carotid artery stenosis
      * iv. Symptomatic carotid disease with ≥ 50% carotid artery stenosis
      * v. Symptomatic lower extremity PAD (ie, intermittent claudication, rest pain, lower extremity ischemic ulceration, or major amputation with either ankle-brachial index ≤ 0.9 or other diagnostic testing \[eg, toe-brachial index, angiogram, or other imaging study\])
      * vi. Prior arterial revascularization procedure (including coronary, carotid, or peripheral angioplasty/stenting, bypass, or atherectomy/endarterectomy)

Exclusion Criteria:

1. Current or planned use of fibrates or agents with PPAR-α agonist activity (eg, saroglitazar) within 6 weeks (42 days) of Visit 1 (Screening/Enrollment Visit). Note: PPAR-γ agonists (eg, glizatones such as pioglitazone and rosiglitazone) are allowed
2. Known sensitivity to PPAR-α agonists or tablet excipients
3. Initiation of, or change in, current TG-lowering therapy within 12 weeks of Visit 1 (if applicable). Note: TG-lowering therapy is defined as niacin \> 100 mg/day or dietary supplements or prescription omega-3 fatty acids \> 1 g/day
4. Type 1 diabetes mellitus

Primary outcomes:
measure: Number of patients with first occurrence of nonfatal MI, nonfatal ischemic stroke, coronary revascularization, or CV death.
timeFrame: Through study completion, an average of 4 years
Secondary outcomes:
measure: Time to first occurrence of The 4-component composite endpoint of non-fatal MI, non-fatal ischemic stroke, hospitalization for unstable angina requiring unplanned coronary revascularization or cardiovascular death
timeFrame: Through study completion, an average of 4 years
measure: Time to first occurrence of the 3-component composite endpoint of non-fatal MI, non-fatal ischemic stroke, or cardiovascular death
timeFrame: Through study completion, an average of 4 years
measure: Time to first occurrence of any component of the primary endpoint or hospitalization for Heart failure (HF)
timeFrame: Through study completion, an average of 4 years
measure: Time to first occurrence of any component of the primary endpoint or all-cause mortality
timeFrame: Through study completion, an average of 4 years
measure: Time to first occurrence of any new or worsening Peripheral artery disease (PAD)
timeFrame: Through study completion, an average of 4 years
measure: Time of first occurrence of individual endpoints and an analysis of total events
timeFrame: Through study completion, an average of 4 years
measure: Incidence of cardiovascular events
timeFrame: Up to 4 Years
measure: Lipid Endpoints
timeFrame: Week -3 to Month 4 (Visit 1 to Visit 5)
measure: Nonfasting Remnant Cholesterol Endpoint
timeFrame: Week 0 to Month 6 (Visit 2 to Visit 6)
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: Synexus Clinical Research US, Inc.
state: Alabama
city: Birmingham
country: United States
facility: University of Alabama at Birmingham
state: Alabama
city: Birmingham
country: United States
facility: VA Medical Center - Birmingham
state: Alabama
city: Birmingham
country: United States
facility: Alabama Clinical Therapeutics, LLC
state: Alabama
city: Gulf Shores
country: United States
facility: Fundamental Research, LLC
state: Alabama
city: Mobile
country: United States
facility: Mobile Heart Specialists, PC
state: Alabama
city: Tuscumbia
country: United States
facility: Terence T. Hart, MD
state: Alabama
city: Chandler
country: United States
facility: Synexus Clinical Research US, Inc.
state: Arizona
city: Mesa
country: United States
facility: Synexus Clinical Research US, Inc.
state: Arizona
city: Peoria
country: United States
facility: Arizona Arthritis & Rheumatology Research, PLLC
state: Arizona
city: Phoenix
country: United States
facility: Phoenix Veterans Adminstration Health Care System
state: Arizona
city: Phoenix
country: United States
facility: Synexus Clinical Research US, Inc.
state: Arizona
city: Surprise
country: United States
facility: Clinical Research Institute of Arizona, LLC
state: Arizona
city: Tucson
country: United States
facility: Synexus Clinical Research US, Inc.
state: Arizona
city: Tucson
country: United States
facility: Eclipse Clinical Research
state: Arizona
city: Little Rock
country: United States
facility: Central Arkansas Veterans Healthcare System
state: Arkansas
city: Alhambra
country: United States
facility: Clinical Research Alliance, Inc
state: California
city: Costa Mesa
country: United States
facility: Aurora Care Clinic
state: California
city: Escondido
country: United States
facility: AMCR Institute, Inc.
state: California
city: Huntington Beach
country: United States
facility: National Institute of Clinical Research
state: California
city: Loma Linda
country: United States
facility: VA Loma Linda Healthcare System
state: California
city: Long Beach
country: United States
facility: VA Long Beach Healthcare System
state: California
city: Los Angeles
country: United States
facility: Eastside Clinical Research Associates
state: California
city: Los Angeles
country: United States
facility: VA Greater Los Angeles Healthcare System
state: California
city: Los Gatos
country: United States
facility: Richard S. Cherlin, MD
state: California
city: Northridge
country: United States
facility: Northridge Clinical Research Inc.
state: California
city: Palo Alto
country: United States
facility: Palo Alto Division
state: California
city: Pasadena
country: United States
facility: Huntington Hospital - Research Department
state: California
city: Rancho Cucamonga
country: United States
facility: Rancho Cucamonga Clinical Research
state: California
city: San Diego
country: United States
facility: MD Strategies Research Centers
state: California
city: Santa Maria
country: United States
facility: Alex Harrison, MD Inc.
state: California
city: Santa Rosa
country: United States
facility: Santa Rosa Cardiology Medical Group, Inc.
state: California
city: Vista
country: United States
facility: Blue Coast Cardiology
state: California
city: Aurora
country: United States
facility: Lynn Institute of Denver
state: Colorado
city: Golden
country: United States
facility: New West Physicians, PC
state: Colorado
city: Littleton
country: United States
facility: Southwest Family Medicine
state: Colorado
city: Waterbury
country: United States
facility: Chase Medical Research, LLC
state: Connecticut
city: West Haven
country: United States
facility: VA Connecticut Healthcare Sys
state: Connecticut
city: Newark
country: United States
facility: Cardiology Physicians, PA
state: Delaware
city: Bay Pines
country: United States
facility: Bay Pines VA Healthcare System
state: Florida
city: Bradenton
country: United States
facility: Meridien Research
state: Florida
city: Brandon
country: United States
facility: Clinical Research Of Brandon, LLC
state: Florida
city: Clearwater
country: United States
facility: Clearwater Cardiovascular Consultants
state: Florida
city: Daytona Beach
country: United States
facility: Daytona Heart Group
state: Florida
city: Delray Beach
country: United States
facility: Cohen Medical Research Associates, LLC
state: Florida
city: Gainesville
country: United States
facility: Malcom Randall VA Medical Center
state: Florida
city: Hollywood
country: United States
facility: Pines Clinical Research, Inc.
state: Florida
city: Homestead
country: United States
facility: Homestead Cardiac & Vein Center
state: Florida
city: Jacksonville
country: United States
facility: Westside Center for Clinical Research
state: Florida
city: Jacksonville
country: United States
facility: Jacksonville Center for Clinical Research
state: Florida
city: Jupiter
country: United States
facility: Health Awareness, Inc.
state: Florida
city: Lakeland
country: United States
facility: Meridien Research
state: Florida
city: Largo
country: United States
facility: Clearwater Cardiovascular & Interventional Consultants
state: Florida
city: Miami
country: United States
facility: University of Miami
state: Florida
city: Miami
country: United States
facility: Advanced Medical Research Institute
state: Florida
city: Ocala
country: United States
facility: Ocala Research Institute, Inc.
state: Florida
city: Ocala
country: United States
facility: Morgan Medical Management & Consultants Inc.
state: Florida
city: Ocoee
country: United States
facility: Endocrine Associates of Florida
state: Florida
city: Orlando
country: United States
facility: Research Physicians Network Alliance
state: Florida
city: Pembroke Pines
country: United States
facility: Andres Patron, D.O., P.A
state: Florida
city: Pembroke Pines
country: United States
facility: DBC Research, Corp
state: Florida
city: Pensacola
country: United States
facility: Langhorne Cardiology Consultants, Inc.
state: Florida
city: Safety Harbor
country: United States
facility: Clearwater Cardiovascular Consultants
state: Florida
city: Saint Petersburg
country: United States
facility: Professional Health Care of Pinellas
state: Florida
city: Tampa
country: United States
facility: James A. Haley VA Medical Center
state: Florida
city: Winter Haven
country: United States
facility: Clinical Research of Central Florida
state: Florida
city: Atlanta
country: United States
facility: Emory University
state: Georgia
city: Cumming
country: United States
facility: Atlanta Heart Specialists, LLC
state: Georgia
city: Decatur
country: United States
facility: VA Medical Center - Atlanta
state: Georgia
city: Dunwoody
country: United States
facility: Alta Pharmaceutical Research Center, Inc.
state: Georgia
city: Tucker
country: United States
facility: Atlanta Heart Specialists, LLC
state: Georgia
city: Champaign
country: United States
facility: Christie Clinic, LLC
state: Illinois
city: Chicago
country: United States
facility: Apex Medical Research, AMR, Inc.
state: Illinois
city: Gurnee
country: United States
facility: Clinical Investigation Specialists, Inc.
state: Illinois
city: Hines
country: United States
facility: Edward Hines Jr. VA Hospital
state: Illinois
city: Normal
country: United States
facility: Advocate Health and Hospitals Corp
state: Illinois
city: North Chicago
country: United States
facility: Captain James A. Lovell Federal Health Care Center
state: Illinois
city: Olympia Fields
country: United States
facility: Specialty Physicians of Illinois
state: Illinois
city: Anderson
country: United States
facility: Community Hospital of Anderson and Madison County, Inc.
state: Indiana
city: Evansville
country: United States
facility: Synexus Clinical Research US, Inc.
state: Indiana
city: Evansville
country: United States
facility: Deaconess Clinic
state: Indiana
city: Indianapolis
country: United States
facility: VA Medical Center - Indianapolis
state: Indiana
city: Munster
country: United States
facility: Cardiovascular Research of Northwest Indiana, LLC
state: Indiana
city: Valparaiso
country: United States
facility: Buynak Clinical Research
state: Indiana
city: Council Bluffs
country: United States
facility: West Broadway Clinic
state: Iowa
city: Des Moines
country: United States
facility: Iowa Diabetes and Endocrinology Research Center, PLC
state: Iowa
city: West Des Moines
country: United States
facility: The Iowa Clinic, PC
state: Iowa
city: Kansas City
country: United States
facility: University of Kansas Medical Center Research Institute, Inc.
state: Kansas
city: Leavenworth
country: United States
facility: VA Eastern Kansas Health Care
state: Kansas
city: Lexington
country: United States
facility: The Research Group of Lexington, LLC
state: Kentucky
city: Louisville
country: United States
facility: Robley Rex VA Medical Center
state: Kentucky
city: Alexandria
country: United States
facility: Cambridge Medical Trials
state: Louisiana
city: Covington
country: United States
facility: Cardiovascular Associates Research, LLC
state: Louisiana
city: Lake Charles
country: United States
facility: Centex Studies Inc.
state: Louisiana
city: Shreveport
country: United States
facility: Overton Brooks VA Medical Center
state: Louisiana
city: Biddeford
country: United States
facility: Southern Maine Health Care
state: Maine
city: Baltimore
country: United States
facility: Baltimore VA medical centre
state: Maryland
city: Baltimore
country: United States
facility: University of Maryland School of Medicine
state: Maryland
city: Baltimore
country: United States
facility: Maryland Cardiovascular Specialists
state: Maryland
city: Hyattsville
country: United States
facility: Medstar Health Research Institute
state: Maryland
city: Salisbury
country: United States
facility: Delmarva Heart Research Foundation, Inc.
state: Maryland
city: Boston
country: United States
facility: Joslin Diabetes Center
state: Massachusetts
city: Haverhill
country: United States
facility: Pentucket Medical Associates
state: Massachusetts
city: Milton
country: United States
facility: South Shore Internal Medicine Associates
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan
state: Michigan
city: Ann Arbor
country: United States
facility: Veterans Affairs Ann Arbor Healthcare System
state: Michigan
city: Buckley
country: United States
facility: Northern Pines Health Center
state: Michigan
city: Cadillac
country: United States
facility: Cadillac Clinical Research, LLC
state: Michigan
city: Flint
country: United States
facility: AA MRC LLC Ahmed Arif Medical Research Center
state: Michigan
city: Lansing
country: United States
facility: Sparrow Clinical Research Institute
state: Michigan
city: Saginaw
country: United States
facility: Covenant Medical Center, Inc.
state: Michigan
city: Minneapolis
country: United States
facility: Minneapolis Heart Institute Foundation
state: Minnesota
city: Richfield
country: United States
facility: Synexus Clinical Research US, Inc.
state: Minnesota
city: Saint Cloud
country: United States
facility: CentraCare Heart & Vascular
state: Minnesota
city: Saint Paul
country: United States
facility: HealthEast Medical Research Institute
state: Minnesota
city: Jackson
country: United States
facility: GV Montgomery VA Medical Center
state: Mississippi
city: Kansas City
country: United States
facility: Kansas City VA Medical Center
state: Missouri
city: Saint Louis
country: United States
facility: Synexus Clinical Research US, Inc.
state: Missouri
city: Kalispell
country: United States
facility: Kalispell Regional Medical Center dba Glacier View Research Institute
state: Montana
city: Omaha
country: United States
facility: VA Nebraska-Western Iowa Health Care System
state: Nebraska
city: Omaha
country: United States
facility: University of Nebraska Medical Center
state: Nebraska
city: Papillion
country: United States
facility: Synexus Clinical Research US, Inc.
state: Nebraska
city: Henderson
country: United States
facility: Synexus Clinical Research US, Inc.
state: Nevada
city: Las Vegas
country: United States
facility: Red Rock Clinical Research LLC
state: Nevada
city: Reno
country: United States
facility: VA Sierra Nevada Health Care System
state: Nevada
city: Nashua
country: United States
facility: Southern New Hampshire Diabetes and Endocrinology
state: New Hampshire
city: Eatontown
country: United States
facility: Monmouth Cardiology Associates
state: New Jersey
city: Linden
country: United States
facility: NJ Heart
state: New Jersey
city: Ridgewood
country: United States
facility: The Valley Hospital
state: New Jersey
city: Albuquerque
country: United States
facility: Raymond G. Murphy VA Medical Center
state: New Mexico
city: Albany
country: United States
facility: Endocrine Group, L.L.P.
state: New York
city: Albany
country: United States
facility: Stratton Veterans Affairs Medical Center - Albany
state: New York
city: Buffalo
country: United States
facility: Buffalo VA Medical Center
state: New York
city: Mineola
country: United States
facility: Winthrop Cardiology Associates
state: New York
city: New York
country: United States
facility: Icahn School of Medicine at Mount Sinai
state: New York
city: Syracuse
country: United States
facility: SUNY Upstate Medical University
state: New York
city: Syracuse
country: United States
facility: VA Medical Center - Syracuse
state: New York
city: Asheboro
country: United States
facility: Randolph Medical Associates
state: North Carolina
city: Asheville
country: United States
facility: OnSite Clinical Solutions, LLC
state: North Carolina
city: Burlington
country: United States
facility: Kernodle Clinic, Inc., Dept. of the Private Diagnostic Clinic, PLLC
state: North Carolina
city: Cary
country: United States
facility: Cary Research Group, LLC
state: North Carolina
city: Cary
country: United States
facility: PMG Research of Cary, LLC
state: North Carolina
city: Charlotte
country: United States
facility: Novant Health - Heart and Vascular Institute
state: North Carolina
city: Charlotte
country: United States
facility: The Presbyterian Hospital
state: North Carolina
city: Charlotte
country: United States
facility: Focus Clinical Research Solutions
state: North Carolina
city: Greensboro
country: United States
facility: Medication Management, LLC
state: North Carolina
city: Greensboro
country: United States
facility: Triad Clinical Trials, LLC
state: North Carolina
city: Hickory
country: United States
facility: Clinical Trials of America-NC, LLC
state: North Carolina
city: Hickory
country: United States
facility: PMG Research of Hickory, LLC
state: North Carolina
city: Mooresville
country: United States
facility: Research Institute of the Carolinas, PLC
state: North Carolina
city: Morehead City
country: United States
facility: Diabetes and Endocrinology Consultants
state: North Carolina
city: Pinehurst
country: United States
facility: Pinehurst Medical Clinic Inc
state: North Carolina
city: Raleigh
country: United States
facility: PMG Research of Raleigh, LLC
state: North Carolina
city: Rocky Mount
country: United States
facility: PMG Research of Rocky Mount, LLC
state: North Carolina
city: Salisbury
country: United States
facility: PMG Research of Salisbury, LLC
state: North Carolina
city: Shelby
country: United States
facility: Carolina Research Center, Inc.
state: North Carolina
city: Akron
country: United States
facility: Synexus Clinical Research US, Inc.
state: Ohio
city: Athens
country: United States
facility: OhioHealth Heart & Vascular Physicians (Heartcare, Inc.) - Athens
state: Ohio
city: Canton
country: United States
facility: Aultman Hospital
state: Ohio
city: Cincinnati
country: United States
facility: Hometown Urgent Care & Occupational Health
state: Ohio
city: Cincinnati
country: United States
facility: Cincinnati Veterans Affairs Medical Center
state: Ohio
city: Cleveland
country: United States
facility: Louis Stokes Cleveland Dept of VA Medical Center
state: Ohio
city: Franklin
country: United States
facility: Prestige Clinical Research Center
state: Ohio
city: Marion
country: United States
facility: Craig S Thompson MD LLC
state: Ohio
city: Norman
country: United States
facility: Intend Research
state: Oklahoma
city: Norman
country: United States
facility: Lynn Institute of Norman
state: Oklahoma
city: Oklahoma City
country: United States
facility: Oklahoma City Clinic - Central
state: Oklahoma
city: Oklahoma City
country: United States
facility: South Oklahoma Heart Research Group
state: Oklahoma
city: Medford
country: United States
facility: Heart Clinic of Southern Oregon
state: Oregon
city: Chambersburg
country: United States
facility: Chambersburg Hospital
state: Pennsylvania
city: Feasterville
country: United States
facility: AMH Feasterville Family Health Care Center
state: Pennsylvania
city: Levittown
country: United States
facility: Family Medical Associates
state: Pennsylvania
city: Pittsburgh
country: United States
facility: VA Pittsburgh Healthcare System
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Preferred Primary Care Physicians
state: Pennsylvania
city: Scottdale
country: United States
facility: Fay West Family Practice
state: Pennsylvania
city: Smithfield
country: United States
facility: Montgomery Medical Inc.
state: Pennsylvania
city: Cumberland
country: United States
facility: Partners in Clinical Research
state: Rhode Island
city: Lincoln
country: United States
facility: Ocean State Clinical Research Partners
state: Rhode Island
city: Providence
country: United States
facility: Providence Veteran Administration Medical Center
state: Rhode Island
city: Anderson
country: United States
facility: Synexus Clinical Research US, Inc.
state: South Carolina
city: Charleston
country: United States
facility: Ralph H. Johnson VA Medical Center
state: South Carolina
city: Greer
country: United States
facility: Mountain View Clinical Research, Inc.
state: South Carolina
city: Indian Land
country: United States
facility: Piedmont Research Partners
state: South Carolina
city: Little River
country: United States
facility: Main Street Physician's Care - Waterway
state: South Carolina
city: Myrtle Beach
country: United States
facility: Family Medicine of Sayebrook
state: South Carolina
city: Spartanburg
country: United States
facility: Palmetto Research Center, LLC
state: South Carolina
city: Summerville
country: United States
facility: Palmetto Clinical Research
state: South Carolina
city: Bristol
country: United States
facility: PMG Research of Bristol, LLC
state: Tennessee
city: Chattanooga
country: United States
facility: Chattanooga Medical Research, LLC
state: Tennessee
city: Chattanooga
country: United States
facility: Chattanooga Research and Medicine (CHARM)
state: Tennessee
city: Chattanooga
country: United States
facility: University Diabetes & Endocrine Consultants
state: Tennessee
city: Chattanooga
country: United States
facility: WR-ClinSearch, LLC
state: Tennessee
city: Kingsport
country: United States
facility: Holston Medical Group, P.C.
state: Tennessee
city: Knoxville
country: United States
facility: Metro Knoxville HMA, LLC
state: Tennessee
city: Memphis
country: United States
facility: VA Medical Center - Memphis
state: Tennessee
city: Nashville
country: United States
facility: Tennessee Valley Healthcare System
state: Tennessee
city: Austin
country: United States
facility: Central Texas Clinical Research, LLC
state: Texas
city: Dallas
country: United States
facility: Protenium Clinical Research
state: Texas
city: Dallas
country: United States
facility: VA Medical Center - Dallas
state: Texas
city: Dallas
country: United States
facility: North Texas Endocrine Center
state: Texas
city: Dallas
country: United States
facility: Research Institute of Dallas, P.A.
state: Texas
city: Dallas
country: United States
facility: Synexus Clinical Research US, Inc.
state: Texas
city: Edinburg
country: United States
facility: Doctors Hospital at Renaissance
state: Texas
city: Fort Worth
country: United States
facility: Texas Health Research & Education Institute
state: Texas
city: Fort Worth
country: United States
facility: Texas Health Physicians Group
state: Texas
city: Fort Worth
country: United States
facility: University of North Texas Health Science Center
state: Texas
city: Fort Worth
country: United States
facility: Diabetes and Thyroid Center of Fort Worth
state: Texas
city: Fort Worth
country: United States
facility: Rockwood Medical Clinic
state: Texas
city: Houston
country: United States
facility: East Texas Cardiology PA
state: Texas
city: Houston
country: United States
facility: Endocrine Associates, LLC
state: Texas
city: Houston
country: United States
facility: Heights Doctors Clinic
state: Texas
city: Houston
country: United States
facility: Associates in Medicine
state: Texas
city: Houston
country: United States
facility: Michael E. DeBakey VA Medical Center
state: Texas
city: Houston
country: United States
facility: Southwest Clinical Trials
state: Texas
city: Hurst
country: United States
facility: Protenium Clinical Research
state: Texas
city: Pearland
country: United States
facility: Houston Methodist Research Institute - CCAT Pearland
state: Texas
city: Plano
country: United States
facility: Clinical Investigations of Texas
state: Texas
city: San Antonio
country: United States
facility: Consano Clinical Research, LLC
state: Texas
city: San Antonio
country: United States
facility: Sant Antonio Premiere Internal Medicine
state: Texas
city: San Antonio
country: United States
facility: Briggs Clinical Research, LLC.
state: Texas
city: San Antonio
country: United States
facility: Schnitzler Cardiovascular Consultants (SCC), PLLC
state: Texas
city: San Antonio
country: United States
facility: Bandera Family Healthcare Research LLC
state: Texas
city: Schertz
country: United States
facility: Northeast Clinical Research of San Antonio
state: Texas
city: Spring
country: United States
facility: Spring Family Practice Associates
state: Texas
city: Tomball
country: United States
facility: Northwest Houston Heart Center
state: Texas
city: Victoria
country: United States
facility: Victoria Heart & Vascular Center
state: Texas
city: Waco
country: United States
facility: Hillcrest Family Health Clinics
state: Texas
city: Farmington
country: United States
facility: Utah Cardiology, P.C. (Davis)
state: Utah
city: White River Junction
country: United States
facility: VA Medical Center
state: Vermont
city: Burke
country: United States
facility: Burke Internal Medicine & Research
state: Virginia
city: Chesapeake
country: United States
facility: Virginia Endocrinology Research
state: Virginia
city: Manassas
country: United States
facility: Carient Heart and Vascular
state: Virginia
city: Richmond
country: United States
facility: Clinical Research Partners, LLC
state: Virginia
city: Richmond
country: United States
facility: McGuire DVA Medical Center
state: Virginia
city: Roanoke
country: United States
facility: Roanoke Heart Institute
state: Virginia
city: Suffolk
country: United States
facility: Suffolk Multispecialty Research
state: Virginia
city: Virginia Beach
country: United States
facility: Corporation Lane Internal Medicine
state: Virginia
city: Green Bay
country: United States
facility: Cardiology Associates of Bellin Health
state: Wisconsin
city: Kenosha
country: United States
facility: Clinical Investigation Specialists Inc
state: Wisconsin
city: La Crosse
country: United States
facility: Mayo Clinic Health System
state: Wisconsin
city: Madison
country: United States
facility: Meriter Medical Group, Inc.
state: Wisconsin
city: Milwaukee
country: United States
facility: Zablocki VA Medical Center
state: Wisconsin
city: Bahia Blanca
country: Argentina
facility: Hospital Interzonal General de Agudos Dr Jose Penna
state: Buenos Aires
city: Bahia Blanca
country: Argentina
facility: Hospital Italiano Regional del Sur
state: Buenos Aires
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Hospital Italiano
state: Buenos Aires
city: La Plata
country: Argentina
facility: CICLO
state: Buenos Aires
city: Mar del Plata
country: Argentina
facility: Centro de Investigaciones Medicas Mar del Plata
state: Buenos Aires
city: Mar del Plata
country: Argentina
facility: Instituto de Investigaciones Clinicas
state: Buenos Aires
city: San Nicolas
country: Argentina
facility: Instituto de Investigaciones Clinicas San Nicolas
state: Buenos Aires
city: San Nicolas
country: Argentina
facility: Instituto Clinico Metabolico
state: Buenos Aires
city: Vicente Lopez
country: Argentina
facility: Clinica Olivos
state: Buenos Aires
city: Caba
country: Argentina
facility: Hospital Sirio Libanes
state: Ciudad Autonoma Buenos Aires
city: Ciudad Autonoma de Bs. As.
country: Argentina
facility: Sanatorio Güemes
state: Ciudad Autonoma Buenos Aires
city: Ciudad Autonoma de Buenos Aires
country: Argentina
facility: Centro Medico Viamonte SRL
state: Ciudad Autonoma Buenos Aires
city: Villa Luro
country: Argentina
facility: CEMEDIC - Centro de Especialidades Medicas
state: Ciudad Autonoma Buenos Aires
city: San Vicente
country: Argentina
facility: Centro Medico Luquez
state: Cordoba
city: San Miguel de Tucuman
country: Argentina
facility: Axismed S.R.L.- Clínica Mayo
state: Tucuman
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Consultorio Dr. Litvak Bruno
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Fundacion Favaloro
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: CIPREC
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Investigaciones Medicas IMOBA S.R.L
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Centro Medico Dra Laura Maffei Investigacion Clinica Aplicada
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: CEDIC Centro de Investigaciones Clinicas
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Instituto Cardiovascular Buenos Aires
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: CCBR - Buenos Aires - AR
city: Cordoba
country: Argentina
facility: Inst. Privado de Inv. Clinicas de Cordoba
city: Cordoba
country: Argentina
facility: Instituto Medico DAMIC
city: Cordoba
country: Argentina
facility: Hospital Privado Centro Medico de Cordoba S.A
city: Cordoba
country: Argentina
facility: Clinica del Prado
city: Corrientes
country: Argentina
facility: Instituto de Cardiologia de Corrientes
city: Salta
country: Argentina
facility: Prevencion Cardiovascular Salta
city: Brasília
country: Brazil
facility: L2IP - Instituto de Pesquisas Clínicas Ltda.
state: Distrito Federal
city: Brasília
country: Brazil
facility: Hospital do Coração do Brasil
state: Distrito Federal
city: Brasília
country: Brazil
facility: CECAP - Centro de Cardiologia Clínica
state: Distrito Federal
city: Brasília
country: Brazil
facility: Hospital Universitário de Brasília
state: Distrito Federal
city: Brasília
country: Brazil
facility: Clínica de Endocrinologia e Metabologia Ltda.
state: Distrito Federal
city: Goiânia
country: Brazil
facility: CARDIOINTERV Centro de Pesquisa S/S
state: Goiás
city: Goiânia
country: Brazil
facility: Via Médica
state: Goiás
city: Goiânia
country: Brazil
facility: HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás
state: Goiás
city: Belo Horizonte
country: Brazil
facility: Hospital Felício Rocho
state: Minas Gerais
city: Belo Horizonte
country: Brazil
facility: CARDRESEARCH - Cardiologia Assistencial
state: Minas Gerais
city: Campina Grande do Sul
country: Brazil
facility: Sociedade Hospitalar Angelina Caron
state: Paraná
city: Curitiba
country: Brazil
facility: Cline Research Center (Leite PS Consultoria Medica LTDA)
state: Paraná
city: Curitiba
country: Brazil
facility: Núcleo de Pesquisa Clínica S/S
state: Paraná
city: Maringá
country: Brazil
facility: Paraná Medical Research Center
state: Paraná
city: Belém
country: Brazil
facility: HUJBB-UFPA - Hospital Universitário João de Barros Barreto - Universidade Federal do Pará
state: Pará
city: Rio de Janeiro
country: Brazil
facility: CCBR Brasil Centro de Pesquisas e Análises Clínicas Ltda.
state: Rio Do Janeiro
city: Natal
country: Brazil
facility: Eurolatino Natal Pesquisas Médicas Ltda.
state: Rio Grande Do Norte
city: Canoas
country: Brazil
facility: Hospital Universitário
state: Rio Grande Do Sul
city: Passo Fundo
country: Brazil
facility: Hospital São Vicente de Paulo
state: Rio Grande Do Sul
city: Pelotas
country: Brazil
facility: Santa Casa de Misericórdia de Pelotas
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Santa Casa de Misericórdia de Porto Alegre
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Hospital de Clínicas de Porto Alegre
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Centro de Pesquisas em Diabetes Ltda.
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Centro de Pesquisa Clínica Maimônides - Maimônides Day Hospital
state: Rio Grande Do Sul
city: Santa Maria
country: Brazil
facility: Centro de Pesquisa Médica Santa Maria Ltda.
state: Rio Grande Do Sul
city: Blumenau
country: Brazil
facility: Maestri e Kormann Consultoria Medico Científica LTDA
state: Santa Catarina
city: Campinas
country: Brazil
facility: Loema - Instituto de Pesquisa Clínica
state: Sao Paulo
city: Campinas
country: Brazil
facility: IPCC - Instituto de Pesquisa Clínica de Campinas
state: Sao Paulo
city: São Bernardo do Campo
country: Brazil
facility: CEMEC - Centro Multidisciplinar de Estudos Clínicos
state: Sao Paulo
city: São José do Rio Preto
country: Brazil
facility: Fundação Faculdade Regional de Medicina de São José do Rio Preto
state: Sao Paulo
city: São José dos Campos
country: Brazil
facility: ISPEM - Instituto São José dos Campos em Pesquisas Médicas
state: Sao Paulo
city: São Paulo
country: Brazil
facility: CPQuali Pesquisa Clínica Ltda.
state: Sao Paulo
city: São Paulo
country: Brazil
facility: CPCLIN - Centro de Pesquisas Clínicas Ltda.
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Clínica Paulista de Doenças Cardiovasculares Ltda.
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Dr. Consulta
state: Sao Paulo
city: São Paulo
country: Brazil
facility: CEPIC - Centro Paulista de Investigação Clínica e Serviços Médicos
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Hospital das Clínicas da Faculdade de Medicina da USP
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Incor - Instituto do Coração - HCFMUSP
state: Sao Paulo
city: Tatuí
country: Brazil
facility: IMC - Instituto de Moléstias Cardiovasculares Tatuí
state: Sao Paulo
city: Votuporanga
country: Brazil
facility: Santa Casa de Votuporanga
state: Sao Paulo
city: Blagoevgrad
country: Bulgaria
facility: MHAT 'Puls' AD
city: Blagoevgrad
country: Bulgaria
facility: MHAT - Blagoevgrad, EOOD
city: Byala
country: Bulgaria
facility: MHAT "Yuliya Vrevska - Byala", EOOD
city: Haskovo
country: Bulgaria
facility: MHAT-Haskovo, AD
city: Pazardzhik
country: Bulgaria
facility: MHAT "Higia", AD - Pazardzhik
city: Pazardzhik
country: Bulgaria
facility: MHAT - Pazardzhik AD
city: Pleven
country: Bulgaria
facility: MHAT "Sv. Pantaleymon - Pleven", OOD
city: Pleven
country: Bulgaria
facility: SHATC Pleven EAD
city: Pleven
country: Bulgaria
facility: UMHAT 'Dr. Georgi Stranski', EAD
city: Plovdiv
country: Bulgaria
facility: UMHAT "Sv. Georgi", EAD
city: Plovdiv
country: Bulgaria
facility: UMHAT "Kaspela", EOOD
city: Ruse
country: Bulgaria
facility: MC Rusemed ltd.
city: Sofia
country: Bulgaria
facility: Diagnostic Consultative Center II - Sofia OOD
city: Sofia
country: Bulgaria
facility: Fifth MHAT - Sofia EAD
city: Sofia
country: Bulgaria
facility: NMTH "Tsar Boris III"
city: Sofia
country: Bulgaria
facility: MHAT - "National Heart Hospital" EAD
city: Sofia
country: Bulgaria
facility: MHAT "Lyulin", EAD
city: Sofia
country: Bulgaria
facility: Acibadem City Clinic Tokuda Hospital Ead
city: Sofia
country: Bulgaria
facility: MC Start - d-r Todor Dimitrov EOOD
city: Sofia
country: Bulgaria
facility: DCC "Alexandrovska", EOOD
city: Sofia
country: Bulgaria
facility: UMHAT "Alexandrovska" EAD
city: Sofia
country: Bulgaria
facility: UMHAT 'Tsaritsa Yoanna - ISUL', EAD
city: Sofia
country: Bulgaria
facility: Fourth MHAT - Sofia EAD
city: Sofia
country: Bulgaria
facility: Diagnostic Consultation Center CONVEX EOOD
city: Sofia
country: Bulgaria
facility: Medical Center Kalimat
city: Sofia
country: Bulgaria
facility: UMHAT 'Sveta Anna' AD
city: Sofia
country: Bulgaria
facility: MC "Synexus - Sofia", EOOD
city: Sofia
country: Bulgaria
facility: UMHAT "SofiaMed", OOD
city: Stara Zagora
country: Bulgaria
facility: MC "Orfey", EOOD
city: Varna
country: Bulgaria
facility: SHATC "Cardiolife", OOD
city: Varna
country: Bulgaria
facility: SHATC - Varna, EOOD
city: Yambol
country: Bulgaria
facility: MHAT "Sv. Panteleymon", AD
city: Calgary
country: Canada
facility: LMC Clinical Research Inc. (Calgary)
state: Alberta
city: Edmonton
country: Canada
facility: ALTA Clinical Research Inc.
state: Alberta
city: Edmonton
country: Canada
facility: Royal Alexandra Hospital, CK Hui Heart Centre
state: Alberta
city: Red Deer
country: Canada
facility: The Bailey Clinic
state: Alberta
city: New Westminster
country: Canada
facility: Fraser Clinical Trials Inc.
state: British Columbia
city: Surrey
country: Canada
facility: Surrey Memorial Hospital
state: British Columbia
city: Vancouver
country: Canada
facility: BC Diabetes As Operated by Dr. TG Elliott, Inc.
state: British Columbia
city: Victoria
country: Canada
facility: Discovery Clinical Services Ltd.
state: British Columbia
city: Winnipeg
country: Canada
facility: Saint Boniface General Hospital
state: Manitoba
city: Winnipeg
country: Canada
facility: Rivergrove Medical Clinic
state: Manitoba
city: Winnipeg
country: Canada
facility: Winnipeg Clinic
state: Manitoba
city: St. John's
country: Canada
facility: Health Sciences Centre
state: Newfoundland and Labrador
city: Barrie
country: Canada
facility: LMC Clinical Research Inc. (Barrie)
state: Ontario
city: Brampton
country: Canada
facility: LMC Clinical Research Inc. (Brampton)
state: Ontario
city: Brampton
country: Canada
facility: Aggarwal and Associates Ltd
state: Ontario
city: Burlington
country: Canada
facility: JBN Medical Diagnostic Services Inc.
state: Ontario
city: Burlington
country: Canada
facility: LMC Clinical Research dba Manna Research Inc. Burlington North
state: Ontario
city: Cambridge
country: Canada
facility: Cambridge Cardiac Care Centre
state: Ontario
city: Cambridge
country: Canada
facility: Joanne F. Liutkus Medicine Professional Corporation
state: Ontario
city: Cambridge
country: Canada
facility: Saul Vizel Professional Medicine Corporation
state: Ontario
city: Concord
country: Canada
facility: LMC Clinical Research Inc. (Thornhill)
state: Ontario
city: Etobicoke
country: Canada
facility: LMC Clinical Research Inc. (Etobicoke)
state: Ontario
city: Guelph
country: Canada
facility: Dawson Road Family Medical Clinic
state: Ontario
city: Nepean
country: Canada
facility: LMC Clinical Research Inc. (Ottawa)
state: Ontario
city: Oakville
country: Canada
facility: LMC Clinical Research Inc. (Oakville)
state: Ontario
city: Oshawa
country: Canada
facility: James Cha, MD
state: Ontario
city: Ottawa
country: Canada
facility: The Ottawa Hospital - Riverside Campus
state: Ontario
city: Peterborough
country: Canada
facility: Kawartha Cardiology Clinical Trials
state: Ontario
city: Scarborough
country: Canada
facility: Scarborough Cardiology Research
state: Ontario
city: Sudbury
country: Canada
facility: Janik Research
state: Ontario
city: Toronto
country: Canada
facility: Humber River Hospital
state: Ontario
city: Toronto
country: Canada
facility: LMC Clinical Research Inc. (Bayview)
state: Ontario
city: Toronto
country: Canada
facility: St. Michael's Hospital
state: Ontario
city: Toronto
country: Canada
facility: LMC Clinical Research dba Manna Research Inc. Toronto
state: Ontario
city: Chicoutimi
country: Canada
facility: Ecogene-21
state: Quebec
city: Greenfield Park
country: Canada
facility: ViaCar Recherche Clinique Inc
state: Quebec
city: Longueuil
country: Canada
facility: Centre de Dépistage et Recherche Cardiovasculaire Rive-Sud
state: Quebec
city: Lévis
country: Canada
facility: Clinique de Cardiologie de Levis
state: Quebec
city: Mirabel
country: Canada
facility: LMC Clinical Research dba Manna Research Inc. Mirabel
state: Quebec
city: Montreal
country: Canada
facility: CHUM Hôtel-Dieu
state: Quebec
city: Montreal
country: Canada
facility: Applied Medical Informatics Research Inc.
state: Quebec
city: Montréal
country: Canada
facility: Clinique Santé Cardio MC
state: Quebec
city: Québec
country: Canada
facility: Recherche Clinique Sigma Inc.
state: Quebec
city: Québec
country: Canada
facility: Clinique Médicale St-Louis (Recherche) inc d/b/a/ Centre de Recherche Saint-Louis
state: Quebec
city: Québec
country: Canada
facility: ALPHA Recherche Clinique
state: Quebec
city: Saint-Laurent
country: Canada
facility: LMC Clinical Research Inc. (Montreal)
state: Quebec
city: St-Jérôme
country: Canada
facility: Recherche Médicale St-Jérôme Inc.
state: Quebec
city: St-Marc-des-Carrieres
country: Canada
facility: Centre Medical des Carrieres
state: Quebec
city: Quebec
country: Canada
facility: DIEX Recherche Quebec Inc.
city: Quebec
country: Canada
facility: Institut Universitaire de Cardiologie et de Pneumologie de Quebec
city: Quebec
country: Canada
facility: Clinique des maladies Lipidiques de Quebec
city: Barranquilla
country: Colombia
facility: Centro de Investigacion Medico Asistencial S.A.S
city: Barranquilla
country: Colombia
facility: IPS Centro Cientifico Asistencial S.A.S
city: Bogota
country: Colombia
facility: Dexa Diab Servicios Médicos Limitada.
city: Bogota
country: Colombia
facility: Solano y Terront Servicios Médicos Ltda.
city: Cartagena
country: Colombia
facility: Centro Cardiovascular Aristides Sotomayor Santa Lucia S.A.S. - IPS ASTALUC S.A.S. IPS
city: Espinal
country: Colombia
facility: Fundación Centro de Investigaciones Biomédicas Riescard
city: Floridablanca
country: Colombia
facility: Fundación Oftalmológica de Santander - FOSCAL
city: Medellin
country: Colombia
facility: Centro de Investigación Clínica CIC
city: Beroun
country: Czechia
facility: Medicentrum Beroun spol. s.r.o.
city: Brno
country: Czechia
facility: Nemocnice Milosrdnych bratri
city: Brno
country: Czechia
facility: Fakultni nemocnice u sv. Anny v Brne
city: Broumov
country: Czechia
facility: EDUMED s.r.o
city: Chocen
country: Czechia
facility: Poliklinika Chocen a.s.
city: Chomutov
country: Czechia
facility: Ordinace pro choroby srdce s.r.o.
city: Chrudim
country: Czechia
facility: MUDr. Jan Hubac s.r.o.
city: Havlickuv Brod
country: Czechia
facility: Nemocnice Havlickuv Brod p.o.
city: Hradec Kralove
country: Czechia
facility: Kardio-Pisova s.r.o.
city: Krnov
country: Czechia
facility: MUDr. Tomas Edelsberger
city: Nachod
country: Czechia
facility: EDUMED s.r.o
city: Olomouc
country: Czechia
facility: Agentura Science Pro Spol. s.r.o.
city: Olomouc
country: Czechia
facility: PreventaMed s.r.o.
city: Ostrava
country: Czechia
facility: CCR Ostrava s.r.o.
city: Prague
country: Czechia
facility: Corintez s.r.o.
city: Praha 10
country: Czechia
facility: MUDr. Jan KVASNICKA CSc. Angiologie kardiologie a interna
city: Praha 1
country: Czechia
facility: Nemocnice na Frantisku
city: Praha 2
country: Czechia
facility: Vseobecna fakultni nemocnice v Praze
city: Praha 8
country: Czechia
facility: ResTrial s.r.o.
city: Praha
country: Czechia
facility: Synexus Czech s.r.o.
city: Rakovnik
country: Czechia
facility: MUDr.Eva Mandakova MBA
city: Slany
country: Czechia
facility: Nemocnice Slany
city: Teplice
country: Czechia
facility: AeskuLab k.s.
city: Trutnov
country: Czechia
facility: Kardiologicka ambulance MUDr. Ferkl s.r.o.
city: Uherske Hradiste
country: Czechia
facility: Clinical Trials Services s.r.o
city: Uherske Hradiste
country: Czechia
facility: MUDr. Nina Zemkova s.r.o.
city: Aalborg
country: Denmark
facility: Bioclinica
city: Aalborg
country: Denmark
facility: Ålborg Universitets Hospital
city: Aarhus
country: Denmark
facility: Aarhus University Hospital
city: Ballerup
country: Denmark
facility: Bioclinica
city: Copenhagen S
country: Denmark
facility: Amager-Hvidovre Hospital
city: Esbjerg
country: Denmark
facility: Sydvestjyds Sygehus Esbjerg
city: Glostrup
country: Denmark
facility: Amager-Hvidovre Hospital
city: Hellerup
country: Denmark
facility: Herlev og Gentofte Hospital
city: Herlev
country: Denmark
facility: Herlev og Gentofte Hospital
city: Herning
country: Denmark
facility: Regionshospitalet Herning-Hospitalsenheden Vest
city: Holbæk
country: Denmark
facility: Holbæk Sygehus
city: Roskilde
country: Denmark
facility: Sjællands Universitetshospital
city: Svendborg
country: Denmark
facility: OUH
city: Vejle
country: Denmark
facility: Bioclinica
city: Chambray Les Tours
country: France
facility: CHU Tours - Hôpital Trousseau
state: Indre Et Loire
city: Nantes cedex 01
country: France
facility: CHU Nantes - Hopital Nord Laënnec
state: Loire Atlantique
city: Paris cedex 18
country: France
facility: Hôpital Bichat - Claude Bernard
state: Paris
city: Freiburg
country: Germany
facility: Universitaetsklinikum Freiburg
state: Baden Wuerttemberg
city: Villingen-Schwenningen
country: Germany
facility: Praxis fuer Praevention und Therapie
state: Baden Wuerttemberg
city: Kuenzing
country: Germany
facility: Gemeinschaftspraxis Dr. Klein/ Minnich
state: Bayern
city: Muenchen
country: Germany
facility: Klinikum der Universitaet Muenchen
state: Bayern
city: Muenchen
country: Germany
facility: Deutsches Herzzentrum Muenchen
state: Bayern
city: Naumburg
country: Germany
facility: GP Dr. Haggenmiller, PD Dr. Michael Jeserich
state: Bayern
city: Elsterwerda
country: Germany
facility: ZKS-Südbrandenburg -center for clinical studies Südbrandenburg GmbH
state: Brandenburg
city: Bad Homburg
country: Germany
facility: Neurologische Praxis Dr. Schoell & Kollegen
state: Hessen
city: Frankfurt
country: Germany
facility: Synexus Clinical Research GmbH
state: Hessen
city: Frankfurt
country: Germany
facility: ClinPhenomics GmbH & Co KG
state: Hessen
city: Schwerin
country: Germany
facility: Klinische Forschung Schwerin GmbH
state: Mecklenburg Vorpommern
city: Bochum
country: Germany
facility: Synexus Clinical Research GmbH
state: Nordrhein Westfalen
city: Dortmund
country: Germany
facility: Gemeinschaftspraxis Diabeteszentrum Dortmund Dr.med. Klaus Busch
state: Nordrhein Westfalen
city: Dortmund
country: Germany
facility: Kardiologische Praxis Gemeinschaftspraxis
state: Nordrhein Westfalen
city: Dortmund
country: Germany
facility: St. Johannes Hospital
state: Nordrhein Westfalen
city: Dortmund
country: Germany
facility: Klinikum Bielefeld gem. GmbH
state: Nordrhein Westfalen
city: Siegen
country: Germany
facility: Zentrum fuer Praevention und Rehabilitation
state: Nordrhein Westfalen
city: Leipzig
country: Germany
facility: Synexus Clinical Research GmbH
state: Sachsen
city: Leipzig
country: Germany
facility: Gemeinschaftspraxis Dr. Taeschner / Dr. Bonigut
state: Sachsen
city: Neumünster
country: Germany
facility: Dr. Uwe Böckmann / Birgit Jacobs - Diabeteszentrum Neumünster
state: Schleswig Holstein
city: Oldenburg
country: Germany
facility: RED - Institut GmbH
state: Schleswig Holstein
city: Erfurt
country: Germany
facility: Katholisches Krankenhaus "St. Johann Nepomuk"
state: Thueringen
city: Berlin
country: Germany
facility: Diabetespraxis Prenzlauer Allee
city: Berlin
country: Germany
facility: Institut fuer klinische Forschung und Entwicklung Berlin GmbH
city: Berlin
country: Germany
facility: Studienzentrum Rankestrasse
city: Berlin
country: Germany
facility: Synexus Clinical Research GmbH
city: Hamburg
country: Germany
facility: Gemeinschaftspraxis fuer innere Medizin und Diabetologie
city: Baja
country: Hungary
facility: Lausmed Kft.
city: Baja
country: Hungary
facility: Principal SMO Kft.
city: Balatonfured
country: Hungary
facility: DRC Gyogyszervizsgalo Kozpont Kft.
city: Bekescsaba
country: Hungary
facility: Bekes Megyei Kozponti Korhaz Dr. Rethy Pal Tagkorhaz
city: Bekescsaba
country: Hungary
facility: Belgyogyaszati es Kardiologiai Maganrendelo
city: Budapest
country: Hungary
facility: Clinexpert Kft.
city: Budapest
country: Hungary
facility: Synexus Magyarorszag Kft.
city: Budapest
country: Hungary
facility: CSALADGYOGYASZ Kft.
city: Budapest
country: Hungary
facility: Semmelweis Egyetem
city: Debrecen
country: Hungary
facility: Borvo Clinic Kft.
city: Debrecen
country: Hungary
facility: Debreceni Egyetem
city: Godollo
country: Hungary
facility: Meditoll Kft.
city: Gyula
country: Hungary
facility: Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaza
city: Gyula
country: Hungary
facility: Synexus Magyarorszag Egeszsegugyi Szolgaltato Kft.- Gyula DRS
city: Hatvan
country: Hungary
facility: BKS Research Kft.
city: Kalocsa
country: Hungary
facility: Z+P MED Egeszsegugyi, Kereskedelmi es Szolgaltato Bt.
city: Kaposvar
country: Hungary
facility: Somogy Megyei Kaposi Mor Oktato Korhaz
city: Komarom
country: Hungary
facility: Selye Janos Korhaz
city: Miskolc
country: Hungary
facility: IPR Hungary Kft.
city: Nagykanizsa
country: Hungary
facility: Kanizsai Dorottya Korhaz
city: Nyiregyhaza
country: Hungary
facility: Medifarma-98 Kft.
city: Nyiregyhaza
country: Hungary
facility: BORBANYA PRAXIS Kft.
city: Oroshaza
country: Hungary
facility: Dr. Nagy Laszlo Kardiologiai Maganrendeles
city: Pecs
country: Hungary
facility: Da Vinci Maganklinika
city: Szekesfehervar
country: Hungary
facility: Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz
city: Szekszard
country: Hungary
facility: Tolna Megyei Balassa Janos Korhaz
city: Veszprem
country: Hungary
facility: Csolnoky Ferenc Korhaz
city: Zalaegerszeg
country: Hungary
facility: Zala Megyei Szent Rafael Korhaz
city: Nellore
country: India
facility: Vijaya Super Speciality Hospital
state: Andhra Pradesh
city: Guwahati
country: India
facility: GNRC Hospital
state: Assam
city: New Delhi
country: India
facility: Loknayak Hospital
state: Delhi
city: New Delhi
country: India
facility: Sir Gangaram Hospital
state: Delhi
city: New Delhi
country: India
facility: Fortis Flight Lieutenant Rajan Dhall Hospital
state: Delhi
city: Ahmedabad
country: India
facility: Ahmedabad Bariatrics and Cosmetics Pvt Ltd.
state: Gujarat
city: Ahmedabad
country: India
facility: S. A. L. Hospital & Medical Institute
state: Gujarat
city: Nadiad
country: India
facility: DDMM Heart Institute
state: Gujarat
city: Surat
country: India
facility: Shri B. D. Mehta Mahavir Heart Institute
state: Gujarat
city: Surat
country: India
facility: BAPS Pramukhswami Hospital
state: Gujarat
city: Vadodara
country: India
facility: Sterling Hospital
state: Gujarat
city: Vadodara
country: India
facility: Rhythm Heart Institute
state: Gujarat
city: Gurgaon
country: India
facility: Medanta The Medicity
state: Haryana
city: Bangalore
country: India
facility: Fortis Hospitals Ltd.
state: Karnataka
city: Belgaum
country: India
facility: K.L.E. Society's Dr. Prabhakar Kore Hospital and Medical Research Centre
state: Karnataka
city: Mysuru
country: India
facility: JSS Hospital
state: Karnataka
city: Thiruvananthapuram
country: India
facility: Medical College
state: Kerala
city: Nagpur
country: India
facility: Meditrina Institute Of Medical Sciences
state: Maharashtra
city: Nashik
country: India
facility: Supe Heart & Diabetes Hospital & Research Centre
state: Maharashtra
city: Pimpri-Chinchwad
country: India
facility: 7-Orange Hospital
state: Maharashtra
city: Pune
country: India
facility: Shree Multispecialty Hospital
state: Maharashtra
city: Pune
country: India
facility: King Edward Memorial Hospital Research Centre
state: Maharashtra
city: Ulhasnagar
country: India
facility: Aashirwad Hospital
state: Maharashtra
city: Bhubaneshwar
country: India
facility: Institute of Medical Sciences and SUM Hospital
state: Orissa
city: Jaipur
country: India
facility: Eternal Heart Care Centre
state: Rajasthan
city: Chennai
country: India
facility: SRM Institutes for Medical Sciences
state: Tamilnadu
city: Chennai
country: India
facility: Institute of Cardiovascular Diseases Madras Medical Mission
state: Tamilnadu
city: Lucknow
country: India
facility: KRM Hospital & Research Centre
state: Uttar Pradesh
city: Varanasi
country: India
facility: Galaxy Hospital
state: Uttar Pradesh
city: Kolkata
country: India
facility: IPGMER and SSKM Hospital
state: West Bengal
city: Delhi
country: India
facility: Maharaja Agrasen Hospital
city: Afula
country: Israel
facility: HaEmek Medical Center
city: Haifa
country: Israel
facility: Bnai Zion Medical Center
city: Haifa
country: Israel
facility: Rambam Health Care Center
city: Haifa
country: Israel
facility: The Lady Davis Carmel Medical Center
city: Holon
country: Israel
facility: Wolfson Medical Center
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center
city: Jerusalem
country: Israel
facility: Hadassah University Hospital - Ein Kerem
city: Nahariya
country: Israel
facility: Galilee Medical Center
city: Petach Tikva
country: Israel
facility: Rabin Medical Center-Beilinson Campus
city: Ramat-Gan
country: Israel
facility: Chaim Sheba Medical Center
city: Rechovot
country: Israel
facility: Kaplan Medical Center
city: Safed
country: Israel
facility: Ziv Medical Center
city: Tel Aviv
country: Israel
facility: Tel Aviv Sourasky Medical Center
city: Tel Aviv
country: Israel
facility: Diabetes Medical Center
city: Nagakute-shi
country: Japan
facility: Aichi Medical University Hospital
state: Aichi-Ken
city: Nagoya-shi
country: Japan
facility: JOHAS Chubu Rosai Hospital
state: Aichi-Ken
city: Nagoya-shi
country: Japan
facility: Kojunkai Daido Clinic
state: Aichi-Ken
city: Nagoya-shi
country: Japan
facility: NHO Nagoya Medical Center
state: Aichi-Ken
city: Obu-shi
country: Japan
facility: National Center For Geriatrics And Gerontology
state: Aichi-Ken
city: Toyoake-shi
country: Japan
facility: Fujita Health University Hospital
state: Aichi-Ken
city: Chiba-shi
country: Japan
facility: Chiba University Hospital
state: Chiba-Ken
city: Matsudo-shi
country: Japan
facility: Kioroshikai Chibanishi General Hospital
state: Chiba-Ken
city: Matsudo-shi
country: Japan
facility: Seikeikai New Tokyo Heart Clinic
state: Chiba-Ken
city: Matsuyama-shi
country: Japan
facility: Ehime Prefectural Central Hospital
state: Ehime-Ken
city: Fukuoka-shi
country: Japan
facility: Fukuoka University Hospital
state: Fukuoka-Ken
city: Kasuga-shi
country: Japan
facility: Fukuoka Tokushukai Hospital
state: Fukuoka-Ken
city: Kitakyushu-shi
country: Japan
facility: Steel Memorial Yawata Hospital
state: Fukuoka-Ken
city: Koga-shi
country: Japan
facility: NHO Fukuoka Higashi Medical Center
state: Fukuoka-Ken
city: Onga-gun
country: Japan
facility: Chiyukai Fukuoka Shinmizumaki Hospital
state: Fukuoka
city: Koriyama-shi
country: Japan
facility: Southern Tohoku Medical Clinic
state: Fukushima-Ken
city: Koriyama-shi
country: Japan
facility: Hoshi General Hospital
state: Fukushima-Ken
city: Fuchu-shi
country: Japan
facility: Nakahama Heart Clinic
state: Hiroshima-Ken
city: Fukuyama-shi
country: Japan
facility: Nippon Kokan Fukuyama Hospital
state: Hiroshima-Ken
city: Higashihiroshima-shi
country: Japan
facility: NHO Higashihiroshima Medical Center
state: Hiroshima-Ken
city: Sapporo-shi
country: Japan
facility: Miyanosawa Clinic of Internal Medicine and Cardiology
state: Hokkaido
city: Hitachinaka-shi
country: Japan
facility: Tanaka Cardiology Clinic
state: Ibaraki-Ken
city: Naka-shi
country: Japan
facility: Nakakinen Clinic Medical Corporation Kensei-kai
state: Ibaraki-Ken
city: Hakusan-shi
country: Japan
facility: Public Central Hospital of Matto Ishikawa
state: Ishikawa-Ken
city: Komatsu-shi
country: Japan
facility: NHI Komatsu Municipal Hospital
state: Ishikawa-Ken
city: Morioka-shi
country: Japan
facility: Kuonkai Kamata Medical Clinic
state: Iwate-Ken
city: Morioka-shi
country: Japan
facility: Iwate Medical University Uchimaru Medical Center Hospital
state: Iwate-Ken
city: Takamatsu-shi
country: Japan
facility: Josuikai Olive Takamatsu Medical Clinic
state: Kagawa-Ken
city: Sagamihara-shi
country: Japan
facility: Sohken Yamamoto Clinic
state: Kanagawa-Ken
city: Yokohama-shi
country: Japan
facility: NHO Yokohama Medical Center
state: Kanagawa-Ken
city: Kumamoto-shi
country: Japan
facility: Kumamoto University Hospital
state: Kumamoto-Ken
city: Tamana-shi
country: Japan
facility: Ryubokai Higashi Diabetes and Cardiovascular Clinic
state: Kumamoto-Ken
city: Kyoto-shi
country: Japan
facility: Ijinkai Takeda General Hospital
state: Kyoto-Fu
city: Kyoto-shi
country: Japan
facility: Kyoto University Hospital
state: Kyoto-Fu
city: Kyoto-shi
country: Japan
facility: Rakuwakai Otowa Hospital
state: Kyoto-Fu
city: Osaki-shi
country: Japan
facility: Sato Hospital
state: Miyagi-Ken
city: Sendai-shi
country: Japan
facility: Tohoku Kosai Hospital
state: Miyagi-Ken
city: Sendai-shi
country: Japan
facility: Sendai Kousei Hospital
state: Miyagi-Ken
city: Oita-shi
country: Japan
facility: Keiwakai Oita Oka Hospital
state: Oita-Ken
city: Okayama-shi
country: Japan
facility: Okayama University Hospital
state: Okayama-Ken
city: Nakagami-gun
country: Japan
facility: Okinawa Tokushukai Chubu Tokushukai Hospital
state: Okinawa-Ken
city: Higashiosaka-shi
country: Japan
facility: Iwasaki Naika Clinic
state: Osaka-Fu
city: Higashiosaka-shi
country: Japan
facility: Takekawa Naika Clinic
state: Osaka-Fu
city: Izumisano-shi
country: Japan
facility: Rinku General Medical Center
state: Osaka-Fu
city: Kashiwara-shi
country: Japan
facility: Shiraiwa Medical Clinic
state: Osaka-Fu
city: Kishiwada-shi
country: Japan
facility: Tokushukai Kishiwada Tokushukai Hospital
state: Osaka-Fu
city: Osaka-shi
country: Japan
facility: Kansai Electric Power Hospital
state: Osaka-Fu
city: Suita-shi
country: Japan
facility: National Cerebral and Cardiovascular Center
state: Osaka-Fu
city: Toyonaka-shi
country: Japan
facility: Senrichuo Ekimae Clinic
state: Osaka-Fu
city: Iruma-gun
country: Japan
facility: IMS Miyoshi General Hospital
state: Saitama-Ken
city: Kawaguchi-shi
country: Japan
facility: Sugiura Clinic
state: Saitama-Ken
city: Tokorozawa-shi
country: Japan
facility: Sanyukai Saino Clinic
state: Saitama-Ken
city: Wako-shi
country: Japan
facility: NHO Saitama National Hospital
state: Saitama-Ken
city: Otsu-shi
country: Japan
facility: Shiga University of Medical Science Hospital
state: Shiga-Ken
city: Hamada-shi
country: Japan
facility: NHO Hamada Medical Center
state: Shimane-Ken
city: Shimotsuke-shi
country: Japan
facility: Jichi Medical University Hospital
state: Tochigi-Ken
city: Bunkyo-ku
country: Japan
facility: Juntendo University Hospital
state: Tokyo-To
city: Chuo-ku
country: Japan
facility: Fukuwa Clinic
state: Tokyo-To
city: Chuo-Ku
country: Japan
facility: Tokyo-Eki Center-Building Clinic
state: Tokyo-To
city: Itabashi-ku
country: Japan
facility: Nomura Clinic
state: Tokyo-To
city: Katsushika-ku
country: Japan
facility: Hosoda Clinic
state: Tokyo-To
city: Meguro-ku
country: Japan
facility: Toyukai Yutenji Medical Clinic (Yutenji Naika)
state: Tokyo-To
city: Shinjuku-ku
country: Japan
facility: Shinjuku Research Park Clinic
state: Tokyo-To
city: Ube-shi
country: Japan
facility: Yamaguchi University Hospital
state: Yamaguchi-Ken
city: Tijuana
country: Mexico
facility: Centro de Investigacion Cardiovascular y Metabolica
state: Baja California Norte
city: Mexico
country: Mexico
facility: Phytomedicamenta S.A. de C.V.
state: Distrito Federal
city: Mexico
country: Mexico
facility: Health Pharma Professional Research S.A. de C.V.
state: Distrito Federal
city: Mexico
country: Mexico
facility: Centro de Atención e Investigación en Factores de Riesgo Cardiovascular Omega S.C.
state: Distrito Federal
city: Mexico
country: Mexico
facility: Instituto Nacional de Ciencias Médicas y Nutricion Dr. Salvador Zubiran
state: Distrito Federal
city: Mexico
country: Mexico
facility: Mentrials S.A. de C.V.
state: Distrito Federal
city: Acapulco de Juárez
country: Mexico
facility: Centro de Investigacion Clinica del Pacifico, S.A. de C.V.
state: Guerrero
city: Guadalajara
country: Mexico
facility: Cardiologia Clinica e Intervencionista
state: Jalisco
city: Zapopan
country: Mexico
facility: Centro de Investigacion Medica de Occidente, S.C.
state: Jalisco
city: Cuautla
country: Mexico
facility: Instituto de Diabetes, Obesidad y Nutrición S.C.
state: Morelos
city: Monterrey
country: Mexico
facility: Universidad Autonoma de Nuevo Leon, Hospital Universitario Dr. Jose Eleuterio Gonzalez
state: Nuevo León
city: Monterrey
country: Mexico
facility: Centro Medico San Francisco
state: Nuevo León
city: San Nicolas de los Garza
country: Mexico
facility: Unidad Medica para la Salud Integral
state: Nuevo León
city: San Juan del Rio
country: Mexico
facility: Centro Integral Medico SJR S.C.
state: Queretaro
city: Madero
country: Mexico
facility: Centro de Estudios de Investigacion Metabolicos y Cardiovasculares S.C.
state: Tamaulipas
city: Aguascalientes
country: Mexico
facility: Centro de Investigacion Cardiometabolica de Aguascalientes S.A de C.V
city: Chihuahua
country: Mexico
facility: Investigacion En Salud Y Metabolismo S.C.
city: Veracruz
country: Mexico
facility: Sociedad de Metabolismo y Corazon S.C
city: Alkmaar
country: Netherlands
facility: Noordwest Ziekenhuisgroep
city: Almelo
country: Netherlands
facility: Ziekenhuisgroep Twente, Almelo
city: Amersfoort
country: Netherlands
facility: Meander Medisch Centrum
city: Amstelveen
country: Netherlands
facility: Ziekenhuis Amstelland
city: Amsterdam
country: Netherlands
facility: BovenlJ Ziekenhuis
city: Amsterdam
country: Netherlands
facility: Amsterdam UMC, Locatie AMC
city: Apeldoorn
country: Netherlands
facility: Gelre ziekenhuizen, locatie Lukas
city: Arnhem
country: Netherlands
facility: Rijnstate
city: Den Haag
country: Netherlands
facility: Haga Ziekenhuis
city: Deventer
country: Netherlands
facility: Deventer Ziekenhuis
city: Dordrecht
country: Netherlands
facility: Albert Schweitzer Ziekenhuis, Dordwijk
city: Ede
country: Netherlands
facility: Gelderse Vallei Ziekenhuis, Ede
city: Eindhoven
country: Netherlands
facility: Catharina Ziekenhuis Eindhoven
city: Haarlem
country: Netherlands
facility: Spaarne Gasthuis, Hoofddorp
city: Heerlen
country: Netherlands
facility: Zuyderland Medisch Centrum - Heerlen
city: Hoogezand
country: Netherlands
facility: Huisartsenpraktijk Gorecht
city: Kloosterhaar
country: Netherlands
facility: Quality Care Research
city: Leiden
country: Netherlands
facility: Leids Universitair Medisch Centrum
city: Roosendaal
country: Netherlands
facility: Bravis Ziekenhuis, Roosendaal
city: Rotterdam
country: Netherlands
facility: Maasstad Ziekenhuis, Zuider
city: Rotterdam
country: Netherlands
facility: Ikazia Ziekenhuis
city: Sliedrecht
country: Netherlands
facility: Albert Schweitzer Ziekenhuis, Zwijndrecht
city: Uden
country: Netherlands
facility: Bernhoven Uden
city: Utrecht
country: Netherlands
facility: UMC Utrecht
city: Utrecht
country: Netherlands
facility: Diakonessenhuis, Utrecht
city: Veldhoven
country: Netherlands
facility: Maxima Medisch Centrum
city: Venlo
country: Netherlands
facility: VieCuri Medisch Centrum
city: Bydgoszcz
country: Poland
facility: NZOZ Centrum Medyczne KERmed
city: Elblag
country: Poland
facility: KARDIOMED Janczska Kociwska Ostki PodckaRekrzSp
city: Gdansk
country: Poland
facility: Poradnia Kardiologiczna Jarosław Jurowiecki
city: Gdansk
country: Poland
facility: Synexus Polska SCM Sp. z o.o. Gdansku
city: Gdansk
country: Poland
facility: Uniwersyteckie Centrum Kliniczne
city: Gdynia
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska w Dziedzinie Kardiologii lek. med. Krzysztof Cymerman
city: Gdynia
country: Poland
facility: Synexus Polska Sp. z o.o. Oddzial w Gdyni
city: Grodzisk Mazowiecki
country: Poland
facility: Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Jana Pawla II
city: Katowice
country: Poland
facility: Synexus Polska Sp. z o.o. Oddzial w Katowicach
city: Katowice
country: Poland
facility: Centrum Medyczne Pratia Katowice II
city: Katowice
country: Poland
facility: SPSK Nr 7 SUM w Katowicach Gornoslaskie CM im. prof. Leszka Gieca
city: Kielce
country: Poland
facility: Specjalistyczna Poradnia Kardiologiczna i Nadciśnienia Tętniczego
city: Krakow
country: Poland
facility: Augustyn Monika
city: Krakow
country: Poland
facility: Krakowskie Centrum Medyczne Sp. z o.o.
city: Lodz
country: Poland
facility: Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi
city: Lodz
country: Poland
facility: NZOZ ALL-MED Centrum Medyczne Specjalistyczne Gabinety Lekarskie
city: Lodz
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska
city: Lublin
country: Poland
facility: KO-MED Centra Kliniczne Lublin II
city: Lublin
country: Poland
facility: Clinical Best Solutions
city: Lublin
country: Poland
facility: NZOZ Twoja Przychodnia
city: Naleczow
country: Poland
facility: NZOZ Osrodek Kardiologii Inwazyjnej -Ikardia
city: Oswiecim
country: Poland
facility: Medicome Sp. z o.o.
city: Poznan
country: Poland
facility: Synexus Polska sp. z o.o. Oddzial w Poznaniu
city: Poznan
country: Poland
facility: Praktyka Lekarska Ewa Krzyzagorska
city: Pulawy
country: Poland
facility: KO-MED Centra Kliniczne Pulawy
city: Ruda Slaska
country: Poland
facility: NZOZ Przychodnia Specjalistyczna H. Rudzki, A. Wittek
city: Rzeszow
country: Poland
facility: Centrum Medyczne Medyk
city: Skierniewice
country: Poland
facility: Clinmed Research
city: Sopot
country: Poland
facility: NZOZ Pro-Cordis Sopockie Centrum Bad. Kardiolog.
city: Sroda Wielkopolska
country: Poland
facility: NSZOZ Medicus
city: Staszow
country: Poland
facility: KO-MED Centra Kliniczne Staszow
city: Szczecin
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska dr n. med. Agnieszka Karczmarczyk Specjalista Chorob
city: Warsaw
country: Poland
facility: NBR Polska
city: Warszawa
country: Poland
facility: Centrum Medyczne Świat Pacjenta
city: Warszawa
country: Poland
facility: Synexus Polska Sp. z o.o. Oddział w Warszawie
city: Wierzchosławice
country: Poland
facility: Centrum Zdrowia Tuchow Sp. z o.o.
city: Wroclaw
country: Poland
facility: Synexus Polska Sp. z o.o. Oddział we Wroclawiu
city: Zamosc
country: Poland
facility: KO-MED Centra Kliniczne Zamosc
city: San Juan
country: Puerto Rico
facility: VA Medical Center - San Juan
city: Bacau
country: Romania
facility: S.C. CMI Dr. Pletea Noemi S.R.L
city: Baia Mare
country: Romania
facility: Cabinet Medical Individual Diabet, Nutritie, Boli Metabolice Dr. Pop Lavinia
city: Brasov
country: Romania
facility: S.C Centrul Medical de Diagnostic si Tratament Ambulator Neomed S.R.L
city: Bucharest
country: Romania
facility: Institutul de Urgenta pentru Boli Cardiovasculare "Prof. Dr. C.C. Iliescu"
city: Bucuresti
country: Romania
facility: S.C Clinica Medicala Data Plus S.R.L
city: Bucuresti
country: Romania
facility: Spitalul Clinic Colentina
city: Bucuresti
country: Romania
facility: Spitalul Clinic de Urgenta "Sfantul Pantelimon"
city: Bucuresti
country: Romania
facility: S.C. Health Net S.R.L
city: Bucuresti
country: Romania
facility: S.C Policlinica CCBR S.R.L
city: Bucuresti
country: Romania
facility: CMI Dr. Stolea T. Violeta - Medic specialist diabet zaharat, nutritie si boli metabolice
city: Buzau
country: Romania
facility: S.C. Medcon S.R.L.
city: Oradea
country: Romania
facility: S.C Grandmed S.R.L
city: Oradea
country: Romania
facility: S.C Pelican Impex S.R.L
city: Pașcani
country: Romania
facility: S.C. Bella Praxis S.R.L
city: Ploiesti
country: Romania
facility: S.C. Diabmed Dr. Popescu Alexandrina S.R.L
city: Ploiesti
country: Romania
facility: CMI Dr Busegeanu Mihaela Magdalena
city: Targu Mures
country: Romania
facility: S.C Mediab S.R.L
city: Timisoara
country: Romania
facility: S.C Medicali's S.R.L
city: Timisoara
country: Romania
facility: Spitalul Clinic Judetean de Urgenta "Pius Brinzeu"
city: Arkhangelsk
country: Russian Federation
facility: SBIH of Arkhangelsk region " First City Clinical hospital n.a. E. E. Volosevich"
city: Barnaul
country: Russian Federation
facility: TSHI "Altay Territorial Cardiologocal dispensary"
city: Ekaterinburg
country: Russian Federation
facility: SEIHPE "Ural SMA of RosZdrav" b.o. LLC "City Hospital #41"
city: Kemerovo
country: Russian Federation
facility: FSHI "MSU of MoIA of RF of Kemerovo Region"
city: Kemerovo
country: Russian Federation
facility: FSBI "Scientific-research Institute for Complex Problems of cardiovascular disease"
city: Kemerovo
country: Russian Federation
facility: NSIH "Departmental Hospital on Station Kemerovo of OJSC "Russian Railways"
city: Kemerovo
country: Russian Federation
facility: SAIH "Kemerovo Regional Clinical Hospital"
city: Krasnoyarsk
country: Russian Federation
facility: TSBIH "Krasnoyarsk Interdistrict Clinical Hospital of Emergency Medical Care n.a. N.S. Karpovich
city: Moscow
country: Russian Federation
facility: SBIH of Moscow "City Clinical Hospital n.a.Bakhrushinykh"
city: Moscow
country: Russian Federation
facility: SBHI "City Polyclinic #2 of Healthcare department of city of Moscow"
city: Moscow
country: Russian Federation
facility: FSBIH "Central Clinical Hospital of Russian Academy of Sciences"
city: Moscow
country: Russian Federation
facility: FSBI "Central Clinical Hospital with Polyclinic of the Department for Presidential Affairs of the RF
city: Moscow
country: Russian Federation
facility: SBEI HPE "Moscow State Medical and Dentistry University n.a. A. I. Evdokimov" of the MoH of the RF
city: Moscow
country: Russian Federation
facility: SBEI HPE "Moscow State Medical and Dentistry University n.a. A. I. Evdokimov" of the MoH of the RF
city: Murmansk
country: Russian Federation
facility: Murmansk Regional Clinical Hospital named after Bayandin
city: Novosibirsk
country: Russian Federation
facility: SBIH of Novosibirsk Region "Clinical Emergency Hospital #2"
city: Novosibirsk
country: Russian Federation
facility: SBIH of Novosibirsk region "City Clinical Hospital # 19"
city: Novosibirsk
country: Russian Federation
facility: FSBSI "Scientific Research Institute of Therapy and Preventive Medicine"
city: Novosibirsk
country: Russian Federation
facility: LLC "RC Medical"
city: Omsk
country: Russian Federation
facility: BIH of Omsk region "Clinical Medico-Sanitary Unit # 9
city: Omsk
country: Russian Federation
facility: Llc Ultramed
city: Perm
country: Russian Federation
facility: SBIH of Perm territory " City Clinical Hospital # 2 n.a. Fedor Khristoforovich Gral"
city: Perm
country: Russian Federation
facility: State Budgetary Healthcare Institution Clinical Medical Sani
city: Perm
country: Russian Federation
facility: SHI "Perm Regional Hospital of War Veterans"
city: Rostov-on-Don
country: Russian Federation
facility: City Emergency Hospital #2
city: Saint-Petersburg
country: Russian Federation
facility: CJSC Clinic complex
city: Saint-Petersburg
country: Russian Federation
facility: FSBI North-West Federal Medical Research Center n.a. V.A. Almazov of MoH RF
city: Saint-Petersburg
country: Russian Federation
facility: Saint-Petersburg SBHI "City outpatient clinic #28"
city: Saint-Petersburg
country: Russian Federation
facility: Pavlov First Saint Petersburg State Medical University
city: Saint-Petersburg
country: Russian Federation
facility: SPb SBIH "City Pokrovskaya Hospital"
city: Saint-Petersburg
country: Russian Federation
facility: LLC Medical Center Mart
city: Saratov
country: Russian Federation
facility: SIH "Saratov City Clinical Hospital # 2 n.a. V.I. Razumovskiy"
city: Sestroretsk
country: Russian Federation
facility: SPb SBIH "City Hospital # 40 of Kurortnyi region"
city: St. Petersburg
country: Russian Federation
facility: SPb SBIH "City Multy-field Hospital # 2"
city: St. Petersburg
country: Russian Federation
facility: LLC "Institute of Medical Examinations"
city: St. Petersburg
country: Russian Federation
facility: Llc "Medinet"
city: St. Petersburg
country: Russian Federation
facility: SPb SBIH "Nikolaevskaya Hospital"
city: Tomsk
country: Russian Federation
facility: FSBI "Research Institute for Cardiology" of Siberian Branch RAMS
city: Tver
country: Russian Federation
facility: SHI "Regional Clinical Hospital"
city: Ulyanovsk
country: Russian Federation
facility: SHI Ulyanovsk Reg Clinical Hospital
city: Yaroslavl
country: Russian Federation
facility: Yaroslavl Regional Clinical Hospital of War Veterans
city: Bardejov
country: Slovakia
facility: Alian s.r.o.
city: Bardejov
country: Slovakia
facility: Thyreomedical s.r.o.
city: Bratislava
country: Slovakia
facility: Metabol KLINIK s.r.o.
city: Bratislava
country: Slovakia
facility: Galenum, s.r.o.
city: Bratislava
country: Slovakia
facility: DIAFA s.r.o.
city: Bratislava
country: Slovakia
facility: Diabet, spol. s.r.o.
city: Bratislava
country: Slovakia
facility: Kardiovaskularne centrum, s.r.o.
city: Bratislava
country: Slovakia
facility: Kardiologicka, interna a sonograficka amb. Kardio-Sanus, sro
city: Bratislava
country: Slovakia
facility: MEDISPEKTRUM PLUS s.r.o.
city: Bratislava
country: Slovakia
facility: MUDr. Vladimir Gergel, s.r.o.
city: Dolny Kubin
country: Slovakia
facility: ENDIAMED, s.r.o.
city: Komarno
country: Slovakia
facility: MEDICUS plus s.r.o.
city: Kosice
country: Slovakia
facility: Human-Care s.r.o.
city: Kosice
country: Slovakia
facility: Sukromna interna a kardiologicka ambulancia
city: Levice
country: Slovakia
facility: DIA- Kontrol s.r.o.
city: Levice
country: Slovakia
facility: CELL B, s.r.o.
city: Lucenec
country: Slovakia
facility: KARDIO 1 s.r.o.
city: Lucenec
country: Slovakia
facility: IN-DIA s.r.o.
city: Nitra
country: Slovakia
facility: MUDr. Zuzana Ochodnicka,
city: Nove Zamky
country: Slovakia
facility: Fakultna nemocnica s poliklinikou Nove Zamky
city: Presov
country: Slovakia
facility: DIABETOL s.r.o.
city: Presov
country: Slovakia
facility: Medispol s.r.o.
city: Roznava
country: Slovakia
facility: Nemocnica s poliklinikou sv. Barbory Roznava a.s.
city: Sahy
country: Slovakia
facility: Peter Farkas MD, s.r.o.
city: Svidnik
country: Slovakia
facility: Interna SK s.r.o.
city: Svidnik
country: Slovakia
facility: Nemocnica arm. generala L. Svobodu Svidnik, a.s.,
city: Trencin
country: Slovakia
facility: Diabetes centrum, s.r.o.
city: Trnava
country: Slovakia
facility: JAL s.r.o.
city: Zilina
country: Slovakia
facility: MEDIVASA s.r.o.
city: Alberton
country: South Africa
facility: Cardiology Clinical Research
state: Gauteng
city: Centurion
country: South Africa
facility: Johese Clinical Research: Unitas
state: Gauteng
city: Johannesburg
country: South Africa
facility: Medicross Roodepoort Clinical Research
state: Gauteng
city: Johannesburg
country: South Africa
facility: Lenasia Clinical Trial Centre
state: Gauteng
city: Johannesburg
country: South Africa
facility: Wits Clinical Research
state: Gauteng
city: Kempton Park
country: South Africa
facility: Clinresco Centres (Pty) Ltd
state: Gauteng
city: Mamelodi East
country: South Africa
facility: Synexus SA - Stanza Clinical Research Centre
state: Gauteng
city: Pretoria
country: South Africa
facility: Seeber, M
state: Gauteng
city: Pretoria
country: South Africa
facility: Emmed Research
state: Gauteng
city: Pretoria
country: South Africa
facility: Synexus SA Watermeyer Clinical Research Centre
state: Gauteng
city: Pretoria
country: South Africa
facility: Johese Clinical Research: Midstream
state: Gauteng
city: Thabazimbi
country: South Africa
facility: Limpopo Clinical Research Initiative
state: Limpopo
city: Moloto
country: South Africa
facility: Dr AA Mahomed Medical Centre
state: Mpumalanga
city: Cape Town
country: South Africa
facility: Synexus Helderberg Clinical Research Centre
state: Western Cape
city: Cape Town
country: South Africa
facility: Corbod Research
state: Western Cape
city: Cape Town
country: South Africa
facility: Tread Research
state: Western Cape
city: Cape Town
country: South Africa
facility: Tiervlei Trial Centre
state: Western Cape
city: Cape Town
country: South Africa
facility: Cape Town Medical Research Centre
state: Western Cape
city: Cape Town
country: South Africa
facility: Paarl Research Centre
state: Western Cape
city: Cape Town
country: South Africa
facility: Groote Schuur Hospital Lipid Laboratory
state: Western Cape
city: Somerset West
country: South Africa
facility: Dr JM Engelbrecht Practice
state: Western Cape
city: Somerset West
country: South Africa
facility: Helderberg Research Institute
state: Western Cape
city: Badalona
country: Spain
facility: Hospital Universitari Germans Trias i Pujol
state: Barcelona
city: Sanlucar de Barrameda
country: Spain
facility: Hospital Virgen del Camino
state: Cádiz
city: Cordoba
country: Spain
facility: Hospital Universitario Reina Sofia
state: Córdoba
city: A Coruña
country: Spain
facility: Complejo Hospitalario Universitario A Coruña
state: La Coruña
city: Santiago de Compostela
country: Spain
facility: Complejo Hospitalario Universitario de Santiago
state: La Coruña
city: Almeria
country: Spain
facility: Hospital Virgen del Mar
city: Barcelona
country: Spain
facility: Hospital del Mar
city: Barcelona
country: Spain
facility: Hospital Quironsalud Barcelona
city: Barcelona
country: Spain
facility: Hospital de la Santa Creu i Sant Pau
city: Barcelona
country: Spain
facility: Hospital Universitari Vall d'Hebron
city: Madrid
country: Spain
facility: Hospital Universitario Ramon y Cajal
city: Málaga
country: Spain
facility: Hospital Regional Universitario de Malaga
city: Sevilla
country: Spain
facility: Nuevas tecnologías en Diabetes y Endocrinología
city: Sevilla
country: Spain
facility: Hospital Quironsalud Infanta Luisa
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Macarena
city: Cherkasy
country: Ukraine
facility: Cherkasy Regional Cardiological Center
city: Cherkasy
country: Ukraine
facility: CI Cherkasy RH of Cherkasy Regional Council
city: Chernivtsi
country: Ukraine
facility: CMI CCH#3 Dep of Ther# w the beds of card profile HSEI of UBSMU
city: Chernivtsi
country: Ukraine
facility: RCI Chernivtsi Regional Endocrinology Center Policlinic Dept SHEI of UBSMU
city: Dnipro
country: Ukraine
facility: CI Dnipropetrovsk City Cl Hosp #9 of Dniprop Reg Council SI DMA of MOH of Ukr Ch of Endocrinology
city: Dnipro
country: Ukraine
facility: Medical Center of Limited Liability Company Medical Center Clinic of Family Medicine
city: Ivano-Frankivsk
country: Ukraine
facility: Regional CH Dept of Endocrinology SHEI Ivano-Frankivsk NMU
city: Ivano-Frankivsk
country: Ukraine
facility: CI Ivano-Frankivsk Reg Cl Card Center Dept of Chronic Ischemic Heart Dis SHEI Ivano-Frank NMU
city: Ivano-Frankivsk
country: Ukraine
facility: Ivano-Frankivsk CCH Dept of Therapy #1 SHEI Ivano-Frankivsk NMU
city: Kharkiv
country: Ukraine
facility: CHI Kharkiv City Student Hosp Therap dept Nat Pharm Univer
city: Kharkiv
country: Ukraine
facility: CNE Prof. O.O. Shalimov Kharkiv City Clinical Hospital #2 KCC
city: Kharkiv
country: Ukraine
facility: GI L.T.Malaya Therapy National Institute of the NAMS of Ukraine
city: Kharkiv
country: Ukraine
facility: State Institution LT Malaya Inst. of Ther. of AMS of Ukraine
city: Kharkiv
country: Ukraine
facility: Railway Transport Kharkiv CH #1 of Healthcare Center Branch of PJSC Ukr Railway
city: Kharkiv
country: Ukraine
facility: Railway Transport Kharkiv CH#1 of Healthcare Center Branch of PJSC Ukrainian Railway
city: Kharkiv
country: Ukraine
facility: MC Doctor Alex Dept of General Practice-Family Medicine Kharkiv MA of PGE
city: Kharkiv
country: Ukraine
facility: CNE City Clin Hosp #8 of KCC Dept of Therapy Kharkiv MA of PGE of MOHU
city: Kherson
country: Ukraine
facility: CI Ye.Ye.Karabelesh Kherson City Clinical Hosp.
city: Kyiv
country: Ukraine
facility: KCCC of Endocr Dept of General Endocrine Pathology O. O. Bogomolets NMU
city: Kyiv
country: Ukraine
facility: Kyiv CCH #12 Dept of Therapy O.O.Bogomolets NMU
city: Kyiv
country: Ukraine
facility: LLC Treatment and Diagnostic Center Adonis Plus
city: Kyiv
country: Ukraine
facility: MC of PHEI Institute of General Practice - Family Medicine
city: Kyiv
country: Ukraine
facility: Medical Center Blagomed Plus LLC
city: Kyiv
country: Ukraine
facility: Med Center 'Ok!Clinic+' of International Institute of Clinical Trials LLC
city: Kyiv
country: Ukraine
facility: MC of Subsidiary Production Unit Med Scient Pract Union Medbud of PJSc Holding Company Kyivmiskbud
city: Kyiv
country: Ukraine
facility: Kyiv CH on Railway Transport #2 of Branch Center of Healthcare Public Company Ukr Railway
city: Kyiv
country: Ukraine
facility: Med Center of Eurolab LLC Policlinic Outpatient Dept O.O.Bogomolets NMU
city: Kyiv
country: Ukraine
facility: SI National Scientific Centre of Radiation Medicine of NAMSU
city: Kyiv
country: Ukraine
facility: SI NSC M.D. Strazhesko Institute of Cardiology of NAMSU
city: Kyiv
country: Ukraine
facility: SI NSС M.D. Strazhesko Institute of Cardiology of NAMSU
city: Kyiv
country: Ukraine
facility: Department of Medical Services and Rehabilitation of State Joint Stock Holding Company Artem
city: Kyiv
country: Ukraine
facility: Medical Center of Limited Liability Company Medical Center Concilium Medical
city: Kyiv
country: Ukraine
facility: CI of Kyiv RC Regional Clinical Hospital #2
city: Kyiv
country: Ukraine
facility: SI V.P.Komisarenko Institute of E&M of NAMSU
city: Kyiv
country: Ukraine
facility: SI V.P.Komisarenko Institute of Endocrinology and Metabolism of NAMSU
city: Lviv
country: Ukraine
facility: Lviv Reg St Clin Treatment - Diagnostic Endocrin Center, Dept of Polyclinic, D.Galytskyy Lviv NMU
city: Lviv
country: Ukraine
facility: Lviv Communal 4th City Clinical Hospital
city: Odesa
country: Ukraine
facility: Center of Reconstructive & Restorative Medicine (University Clinic) of Odessa National Medical Uni
city: Sumy
country: Ukraine
facility: CI Sumy City Clinical Hospital #1 Dept of Therapy Sumy SU Med Inst
city: Ternopil
country: Ukraine
facility: Ternopil City Municipal Hospital #2 Dept of Gastroenterology Ternopil I.Ya. Gorbachevskyi SMU
city: Uzhgorod
country: Ukraine
facility: Transcarpathian Regional Clinical Cardiology Dispansery
city: Vinnytsia
country: Ukraine
facility: Private Small Enterprise Medical Center Pulse
city: Vinnytsia
country: Ukraine
facility: Vinnytsia RC Highly Special.Endocr.Center Dept of Therapy #2 M.I. Pyrogov NMU
city: Vinnytsia
country: Ukraine
facility: National Pirogov Memorial Medical University
city: Vinnytsia
country: Ukraine
facility: SRI of Invalid Rehabilitation (EST Complex) of Vinnytsia M.I.Pyrogov NMU MOHU
city: Zaporizhzhia
country: Ukraine
facility: CI Zapor CCH#10 SI ZMA PGE Ch of therapy clin pharmacol & endocrin
city: Zhytomyr
country: Ukraine
facility: CI Central City Hospital #1 of Zhytomyr
city: Zhytomyr
country: Ukraine
facility: Zhytomyr regional clinical hospital n.a. O.F. Gerbachevskyy
city: Reading
country: United Kingdom
facility: Synexus Thames
state: Berkshire
city: Hayle
country: United Kingdom
facility: Mounts Bay Medical Ltd
state: Cornwall
city: Liskeard
country: United Kingdom
facility: Oak Tree Surgery
state: Cornwall
city: Penzance
country: United Kingdom
facility: The Alverton Practice
state: Cornwall
city: Torpoint
country: United Kingdom
facility: Rame Medical Limited
state: Cornwall
city: Plymouth
country: United Kingdom
facility: Knowle House Surgery
state: Devon
city: Torquay
country: United Kingdom
facility: Torbay Hospital
state: Devon
city: Stockton on Tees
country: United Kingdom
facility: Synexus Clinical Research North Tees
state: Durham
city: Chelmsford
country: United Kingdom
facility: Broomfield Hospital
state: Essex
city: London
country: United Kingdom
facility: Barts Hospital
state: Greater London
city: Manchester
country: United Kingdom
facility: Manchester Royal Infirmary
state: Greater Manchester
city: Manchester
country: United Kingdom
facility: Synexus Manchester Clinical Research Centre
state: Greater Manchester
city: Blackpool
country: United Kingdom
facility: Waterloo Medical Centre
state: Lancashire
city: Chorley
country: United Kingdom
facility: Synexus Lancashire Clinical Research Centre
state: Lancashire
city: Liverpool
country: United Kingdom
facility: Synexus Merseyside Clinical Research Centre
state: Merseyside
city: Hexham
country: United Kingdom
facility: Synexus Hexham General Hospital
state: Northumberland
city: Cardiff
country: United Kingdom
facility: Synexus Wales Clinical Research Centre
state: South Glamorgan
city: Glasgow
country: United Kingdom
facility: Synexus Scotland Clinical Research Centre
state: Strathclyde
city: Dundee
country: United Kingdom
facility: Ninewells Hospital
state: Tayside Region
city: Birmingham
country: United Kingdom
facility: Synexus Birmingham Clinical Research Centre
state: West Midlands
city: Swansea
country: United Kingdom
facility: Morriston Hospital
Study officials:
affiliation: CCVDP & The Brigham and Women's Hospital
name: Paul Ridker, MD
role: STUDY_DIRECTOR
affiliation: CCVDP & The Brigham and Women's Hospital
name: Aruna Pradhan, MD
role: STUDY_DIRECTOR
References:
citation: Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Pall D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5.
citation: Pradhan AD, Paynter NP, Everett BM, Glynn RJ, Amarenco P, Elam M, Ginsberg H, Hiatt WR, Ishibashi S, Koenig W, Nordestgaard BG, Fruchart JC, Libby P, Ridker PM. Rationale and design of the Pemafibrate to Reduce Cardiovascular Outcomes by Reducing Triglycerides in Patients with Diabetes (PROMINENT) study. Am Heart J. 2018 Dec;206:80-93. doi: 10.1016/j.ahj.2018.09.011. Epub 2018 Sep 29.