Clinical trial NCT03878680: Prevalence of Asthma and Allergies Among Children in UAE
Official title: Prevalence of Asthma and Allergies Among Children in UAE-A Cross-sectional Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Asthma
Lead sponsor: AstraZeneca
Sponsor class: INDUSTRY
First posted: 2019-03-18
Enrollment: 3737
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Children with age 6-7 years or with age 13-14 years at the time of questionnaires completion, and residing in Dubai and the Northern Emirates of UAE

Brief summary: Multicenter, cross-sectional study to recruit a random sample of 6000 children via school class registers: 3000 children aged 13-14 years and 3000 children aged 6-7 years.

Detailed description: Multicenter, cross-sectional study to recruit a random sample of 6000 children via school class registers: 3000 children aged 13-14 years and 3000 children aged 6-7 years.Standard ISAAC core questions for wheezing, rhinitis, and atopic dermatitis will be used. The ISAAC questionnaire has been validated by the World Health Organization and translated into many languages, and used in many countries. In this study, the Arabic and English version will be used. In addition, questions regarding exposure to Arabian incense "Bokhor" and smoking questions of the environmental questionnaire will be included.

ISAAC Questionnaires

1. Core questionnaire on wheezing.
2. Core questionnaire on rhinitis.
3. Core questionnaire on atopic dermatitis.
4. Smoking questions of the environmental questionnaire.
5. Video questionnaire on wheezing (only for 13-14 years age group, if applicable)

Eligibility criteria: Inclusion Criteria:

* Children with age 6 to 7 years or with age 13 to 14 years at the time of questionnaires completion, and residing in Dubai and the Northern Emirates of UAE.
* Children aged 6 to 7 years or 13 to14 years, whose legal guardians give their consent.
* Able to give assent in the 13 to 14 years group.
* Able to comprehend and answer the questionnaire themselves in the 13 to 14 years group.

Exclusion Criteria:

* Aged 13 to 14 years and unable to answer the questionnaire due to physical or mental disability.
* Parent or legal guardian refuses sign and return consent for the 6 to 7 years group and the 13 to 14 years group.

Primary outcomes:
measure: Prevalence of asthma in children aged 6-7 years and 13-14 years in Dubai and the Northern Emirates.
timeFrame: 3 Month
Secondary outcomes:
measure: Severity of asthma in children aged 6-7 years and 13-14 years in Dubai and the Northern Emirates.
timeFrame: 3 Month
Other outcomes:
measure: Prevalence of asthma in children aged 6-7 years and 13-14 years in Dubai and the Northern Emirates, who were exposed to Arabian incense "Bokhor".
timeFrame: 3 Month
measure: Prevalence of asthma in children aged 6-7 years and 13-14 years in Dubai and the Northern Emirates, who were exposed to tobacco smoke
timeFrame: 3 Month
Locations:
city: Ajman
country: United Arab Emirates
facility: Research Site
city: Dubai
country: United Arab Emirates
facility: Research Site
city: FUJ
country: United Arab Emirates
facility: Research Site
city: RAK
country: United Arab Emirates
facility: Research Site
city: Sharjah
country: United Arab Emirates
facility: Research Site
city: UMQ
country: United Arab Emirates
facility: Research Site
Study officials:
References: