Clinical trial NCT05241015: Effect of Sensorimotor Training on Upper Extremity in Parkinson's Patients
Official title: Investigation of the Effect of Sensorimotor Training on Upper Extremity Functions, Activity and Participation in Parkinson's Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease
Keywords: Parkinson
Upper Extremity
Sensorimotor Training
ICF
Function
Lead sponsor: Hacettepe University
Sponsor class: OTHER
Collaborators: name: TC Erciyes University
name: Nuh Naci Yazgan University
First posted: 2022-02-15
Enrollment: 27
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: There are many factors affecting the upper extremity such as tremor, bradykinesia, rigidity, and postural instability in Parkinson's patients. According to the International Classification of Functioning, Disability and Health (ICF) model, there are restrictions on people's activities and participation in life due to structural and functional disorders affecting the upper extremity in PD.

In PD, integrating and using proprioceptive feedback, sensorimotor integration and peripheral sensory functions are reported to be impaired. Numerous studies show that the main source of motor problems in PD is dysfunction of sensorimotor integration. Since the cervical region contains a dense concentration of proprioceptive organs such as muscle spindles, it plays an important role in providing afferent proprioceptive information for postural control. Therefore, sensorimotor training targeting the cervical region gains importance. In this study, we aim to reduce PD-specific upper extremity disorders and related activity and participation limitations by increasing motor control in the cervical region with sensorimotor training. Patients with Parkinson's disease will be included in the study and randomly divided into 2 groups. While the general physiotherapy program will be applied to the control group, sensorimotor training will be given in addition to the exercise group.


Eligibility criteria: Inclusion Criteria:

* Having idiopathic Parkinson's disease over the age of 40
* Meets the diagnostic criteria of the United Kingdom Parkinson's Disease Society Brain Bank
* Hoehn-Yahr Staging \<3
* Mini mental test score of 24 and above
* In the "on" period
* Receiving oral therapy only

Exclusion Criteria:

* Patients receiving device-assisted therapy
* Patients receiving apomorphine therapy
* Patients with mini mental test scores below 24
* Patients who use drugs (antidepressants, etc.) that will affect cognitive functions
* Patients with hearing and speech problems
* Patients with orthopedic, neurological and vestibular problems other than Parkinson's that may prevent them from completing the tests and treatment

Primary outcomes:
measure: Posture Analysis
timeFrame: Change from baseline at 8 week
measure: Tremor
timeFrame: Change from baseline at 8 week
measure: Unified Parkinson's Disease Rating Scale
timeFrame: Change from baseline at 8 week
measure: Proprioception
timeFrame: Change from baseline at 8 week
measure: Tactile acuity
timeFrame: Change from baseline at 8 week
measure: Touch threshold
timeFrame: Change from baseline at 8 week
measure: Pain threshold
timeFrame: Change from baseline at 8 week
measure: Pain intensity
timeFrame: Change from baseline at 8 week
measure: Hand Grip Strength
timeFrame: Change from baseline at 8 week
measure: Pinch Grip Strength
timeFrame: Change from baseline at 8 week
measure: Endurance of Cervical Muscles
timeFrame: Change from baseline at 8 week
measure: Fatigue
timeFrame: Change from baseline at 8 week
measure: Hand functions
timeFrame: Change from baseline at 8 week
measure: Dual Task Performance
timeFrame: Change from baseline at 8 week
measure: Disabilities of the Arm, Shoulder and Hand Questionnaire
timeFrame: Change from baseline at 8 week
measure: Quality of life evaluation
timeFrame: Change from baseline at 8 week
measure: Evaluation of Environmental Factors
timeFrame: Change from baseline at 8 week
measure: Motor speed
timeFrame: Change from baseline at 8 week
Secondary outcomes:
Other outcomes:
Locations:
city: Kayseri
country: Turkey
facility: Nuh Naci Yazgan University, Department of Physiotherapy and Rehabilitation
Study officials:
References: