Clinical trial NCT04488211: IVM Survey Among Reproductive Medicine Specialists
Official title: Survey of Fertility Specialists' Knowledge of, Experience With, and Attitudes Toward the Use of in Vitro Maturation of Oocytes in Reproductive Medicine
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: IVM
Lead sponsor: Universitair Ziekenhuis Brussel
Sponsor class: OTHER
Collaborators: name: CooperSurgical Inc.
First posted: 2020-07-27
Enrollment: 200
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Fertility specialists around the globe who are affiliated to a public or private fertility clinic. Clinics will be identified based on whether they have worked with IVM previously but stopped, and clinics with appropriate size to offer IVM competence.

Brief summary: Although IVM as a laboratory technology in reproductive medicine has existed for many decades, there is a lack of well-designed studies comparing the efficiency and the patient satisfaction related to IVM as compared to standard ovarian stimulation for IVF. In view of this, and in order to identify unmet needs of fertility specialists with regard to the application of IVM, the investigator developed the idea of a worldwide web-based survey analysis of fertility specialists' insights and experiences regarding IVM.

Detailed description: The IVM survey will be structured as a series of open questions and multiple-choice questions. In most of the questions, a single answer will be required by participants. A small number of questions will allow multiple answers. The survey will be web-based. Invitations to participate in the survey will be emailed on three occasions to selected fertility specialists worldwide who are affiliated to a public or private fertility clinic. Clinics will be identified based on whether they have worked with IVM previously but stopped, and clinics with appropriate size to offer IVM competence. When no response is obtained from selected fertility specialists, e-mails will be sent to affiliated colleagues working at the same fertility clinic. When analyzing the survey results, care will be taken to analyse the responses per fertility clinic, as responses from different fertility specialists working in the same fertility clinic should be avoided. Results will be analysed using a method that assigns equal weight per clinic and a method that weights clinic responses based on treatment volume (number of IVF cycles).

Eligibility criteria: Inclusion Criteria:

* IVF clinics that have worked with IVM previously but stopped
* clinics with appropriate size to offer IVM

Primary outcomes:
measure: Name of the measurement: Application of in vitro maturation (IVM) of oocytes as a laboratory tool
timeFrame: 1 month
measure: Name of the measurement: Appreciation of IVM as a laboratory technique
timeFrame: 1 month
Secondary outcomes:
measure: Name of the measurement: Annual number of egg retrievals for IVM
timeFrame: 1 month
Other outcomes:
Locations:
city: Brussel
country: Belgium
facility: Universitair Ziekenhuis Brussel
Study officials:
affiliation: Universitair Ziekenhuis Brussel
name: Michel De Vos
role: PRINCIPAL_INVESTIGATOR
References: