Clinical trial NCT04020692: Home Improvement Initiative of the TRaitement Optimisé Medicamenteux After Hospitalization
Official title: Home Improvement Initiative of the TRaitement Optimisé Medicamenteux After Hospitalization
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Older Adult
Chronic Disease
Clinical Pharmacy
Surgery
Ambulatory Care
Keywords: Multicenter study
Before-and-after type study
Minimal risks and constraints
Lead sponsor: University Hospital, Strasbourg, France
Sponsor class: OTHER
First posted: 2019-07-16
Enrollment: 223
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The issue of drug continuity after hospital discharge has become a major issue in recent years. When patients return home, the drugs taken do not correspond to the treatments prescribed at the end of the hospitalization. This is due to appropriate or inappropriate initiatives of the patients (or their relatives) and/or the physicians accompanying them. Prescribed medications, on the other hand, are almost always dispensed by community pharmacists.

The scope chosen in this project is that the intervention of an operational clinical pharmacy team (EOPC), targeting both patient and health care professionals (inpatient and outpatient), will maintain, in outpatient care, the drugs treatments that have been optimized during hospitalization
Primary purpose: SUPPORTIVE_CARE

Brief summary: The hypothesis is that the intervention of an operational clinical pharmacy team (EOPC), targeting both patients and hospital and health care professionals, allows: i) to initiate a therapeutic review during hospitalization, ii) to accompany the patients upon hospital discharge, iii) to maintain, in outpatient care, the drug treatments that have been optimized during hospitalization.

The main objective of the study is to demonstrate that the intervention of an EOPC in surgical departments and then in outpatient care makes it possible to maintain, 45 days after the discharge of the patients aged 65 years and over, the chronic outpatient treatments revised and optimized during the hospital stay.

The secondary objectives are to measure the impacts of EOPC's intervention on:

* unexpected readmissions, emergency use, medical complications and adverse drug reactions;
* patient and health professional satisfactions (community pharmacists and physicians);
* the costs of drug treatments in ambulatory care.


Eligibility criteria: Inclusion Criteria:

* Patient (man or woman)
* age ≥ 65 years with more than 3 drugs taken for 3 months, stay in surgery with a duration of ≥ 1 days including urgent surgery;
* affiliated to a social health insurance scheme;
* for whom a return home is possible;
* able to understand the objectives of the research and give informed, dated and signed consent.

Exclusion Criteria:

* Patient (man or woman)
* with as a hospital discharge an entry into a nursing home or long-term care called "important medical and technical care (SMTI);
* with cognitive or other problems preventing consent (at the discretion of the geriatric expertise team);
* under the safeguard of justice;
* under tutorship or curatorship.

Primary outcomes:
measure: Compliance of patients' medication intake at 45 days (D45) compared to the discharge prescription (D0): drugs prescribed and taken by patients (chronic disease treatments only)
timeFrame: 45 days
Secondary outcomes:
Other outcomes:
Locations:
city: Strasbourg
country: France
facility: Groupe Hospitalier Saint Vincent
city: Strasbourg
country: France
facility: Les Hôpitaux Universitaires de Strasbourg
Study officials:
References: