Clinical trial NCT05030428: Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease
Official title: A Randomized, Double-blind, Placebo-controlled, Multicenter Trial, Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Participants With Established Cardiovascular Disease (VICTORION-2 PREVENT)
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: PHASE3
Conditions: Atherosclerotic Cardiovascular Disease
Keywords: Atherosclerotic cardiovascular disease
Hypercholesterolemia
Dyslipidemia
high cholesterol
Hyperlipidemia
Inclisiran
siRNA
KJX839
Lead sponsor: Novartis
Sponsor class: INDUSTRY
First posted: 2021-09-01
Enrollment: 17004
Sex: ALL
Minimum age (years): 40
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: randomized, double-blind, parallel group, placebo-controlled, multi-center, event-driven study
Primary purpose: TREATMENT

Brief summary: Study CKJX839B12302 is a pivotal Phase III trial to evaluate the benefits of inclisiran on major adverse cardiovascular (MACE) events in participants with established cardiovascular disease (CVD).

Detailed description: Purpose of this study is to test the hypothesis that treatment with inclisiran sodium 300 mg s.c. administered on Day 1, Month 3 (Day 90), and every 6 months thereafter taken in addition to well-tolerated high-intensity statin therapy in participants with established ASCVD will significantly reduce the risk of 3-Point-Major Adverse Cardiovascular Events (3P-MACE) defined as a composite of CV death, non-fatal myocardial infarction (MI) and non-fatal ischemic stroke. This will be compared to placebo in adjunct to well-tolerated high-intensity statin therapy.

Eligibility criteria: Inclusion Criteria:

1. Fasting LDL-C ≥ 70 mg/dL at randomization visit
2. Stable (greater than or equal to 4 weeks) and well-tolerated lipid-lowering regimen (including e.g. with or without Ezetimibe) that must include a high-intensity statin therapy with either atorvastatin greater than or equal to 40 mg QD or rosuvastatin greater than or equal to 20 mg QD
3. Established CV disease defined as ANY of the following three conditions

   1. Spontaneous Myocardial infarction ≥ 4 weeks from screening visit
   2. History of ischemic stroke occurred ≥ 4 weeks prior to the Screening visit
   3. Symptomatic peripheral arterial disease (PAD) evidenced by either intermittent claudication with ankle brachial index (ABI) \< 0.85, prior peripheral arterial revascularization procedure, or, amputation due to atherosclerotic disease.

Exclusion Criteria:

1. Acute coronary syndrome, stroke, peripheral arterial revascularization procedure or amputation due to atherosclerotic disease \< 4 weeks before screening visit
2. Treatment with PCSK9 inhibitors (e.g. evolocumab, alirocumab) within 90 days or planned use post first study visit
3. Planned or expected cardiac, cerebrovascular or peripheral artery surgery or re-vascularization within the 6 months after the first study visit
4. Heart failure NYHA class III or IV
5. Active liver disease defined as any known current infectious, neoplastic, or metabolic pathology of the liver
6. Previous exposure to inclisiran or any other non-mAb PCSK9-targeted therapy, either as an investigational or marketed drug within 2 years
7. Severe concomitant non-CV disease that is expected to reduce life expectancy to less than 5 years
8. History of malignancy that required surgery radiation therapy and/or systemic therapy during the 3 years prior to the first study visit
9. Pregnant or nursing (lactating) women

Other protocol-defined inclusion/exclusion criteria may apply.

Primary outcomes:
measure: Time to First Occurrence of 3P-MACE (3-Point Major Adverse Cardiovascular Events)
timeFrame: From randomization to total follow-up time (up to 72 months)
Secondary outcomes:
measure: Time to Occurrence of Cardiovascular (CV) Death
timeFrame: From randomization to total follow-up time (up to 72 months)
measure: Time to First Occurrence of 4P-MACE (4-Point Major Adverse Cardiovascular Events)
timeFrame: From randomization to total follow-up time (up to 72 months)
measure: Time to first occurrence of Major Limb Adverse Events (MALE)
timeFrame: From randomization to total follow-up time (up to 72 months)
measure: Time to occurrence of all-cause death
timeFrame: From randomization to total follow-up time (up to 72 months)
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: Ascension St Vincents
state: Alabama
city: Fairhope
country: United States
facility: Eastern Shore Research Institute
state: Alabama
city: Foley
country: United States
facility: G and L Research LLC
state: Alabama
city: Anchorage
country: United States
facility: Alaska Heart and Vascular
state: Alaska
city: Gilbert
country: United States
facility: Mercy Gilbert Medical Center
state: Arizona
city: Mesa
country: United States
facility: Cardiovascular Associates of Mesa
state: Arizona
city: Phoenix
country: United States
facility: Elite Clinical Studies
state: Arizona
city: Scottsdale
country: United States
facility: HonorHealth Heart Group Deer Valley
state: Arizona
city: Sun City West
country: United States
facility: Clinical Research Inst of Arizona
state: Arizona
city: Tucson
country: United States
facility: Pima Heart And Vascular Clin Rch
state: Arizona
city: Little Rock
country: United States
facility: ARcare Center for Clinical Research
state: Arkansas
city: Little Rock
country: United States
facility: Arkansas Clinical Research
state: Arkansas
city: Bakersfield
country: United States
facility: Central Cardiology Medical Center
state: California
city: Canoga Park
country: United States
facility: Hope Clinical Research
state: California
city: Concord
country: United States
facility: John Muir Physician Network Clinical Research Center
state: California
city: Fullerton
country: United States
facility: ASCADA Research
state: California
city: Huntington Beach
country: United States
facility: Diabetes Lipid Management Center
state: California
city: Irvine
country: United States
facility: University of Calif Irvine Med Cntr
state: California
city: La Jolla
country: United States
facility: UC San Diego Health
state: California
city: Los Angeles
country: United States
facility: American Institute of Research
state: California
city: Los Angeles
country: United States
facility: Keck Medical Center USC
state: California
city: Los Angeles
country: United States
facility: University of California LA
state: California
city: Palo Alto
country: United States
facility: VA Palo Alto Health Care System
state: California
city: San Diego
country: United States
facility: San Diego Veterans Medical Center
state: California
city: San Ramon
country: United States
facility: West Coast Research LLC
state: California
city: Santa Ana
country: United States
facility: Helping Hands Medical Associates INC
state: California
city: Santa Ana
country: United States
facility: Syrentis Clinical Research
state: California
city: Spring Valley
country: United States
facility: Encompass Clinical Research
state: California
city: Stanford
country: United States
facility: Stanford University Medical Center
state: California
city: Stockton
country: United States
facility: Manshadi Heart Institute
state: California
city: Torrance
country: United States
facility: Uni of California at Los Angeles
state: California
city: Tustin
country: United States
facility: Tilda Research
state: California
city: Vista
country: United States
facility: Blue Coast Research Center LLC
state: California
city: West Hills
country: United States
facility: Interv Cardiology Med Grp
state: California
city: Aurora
country: United States
facility: Aurora Denver Cardiology Associates
state: Colorado
city: Aurora
country: United States
facility: Rocky Mountain Regional VA Med Ctr
state: Colorado
city: Bridgeport
country: United States
facility: Bridgeport Hospital
state: Connecticut
city: Greenwich
country: United States
facility: d-b-a Greenwich Cardio Assoc
state: Connecticut
city: Waterbury
country: United States
facility: Chase Medical Research LLC
state: Connecticut
city: Washington
country: United States
facility: Emerson Clinical Research Institute
state: District of Columbia
city: Boca Raton
country: United States
facility: Excel Medical Clinical Trials LLC
state: Florida
city: Bradenton
country: United States
facility: Cardiovascular and Vein Center of Florida
state: Florida
city: Bradenton
country: United States
facility: Nova Clinical Research LLC
state: Florida
city: Clearwater
country: United States
facility: Bay Care Medical Group
state: Florida
city: Daytona Beach
country: United States
facility: Cardiology Research Associates
state: Florida
city: DeLand
country: United States
facility: Hillcrest Medical Research
state: Florida
city: Hialeah
country: United States
facility: Indago Research and Health Ctr Inc
state: Florida
city: Hialeah
country: United States
facility: National Research Institute
state: Florida
city: Hialeah
country: United States
facility: Sister Life Research Inc
state: Florida
city: Hollywood
country: United States
facility: Zenith Clinical Research
state: Florida
city: Jacksonville Beach
country: United States
facility: Baptist Heart Specialists
state: Florida
city: Jacksonville
country: United States
facility: Westside Center for Clinical Research
state: Florida
city: Jacksonville
country: United States
facility: University of Florida Health Science Center
state: Florida
city: Lake Worth
country: United States
facility: United Vein and Vascular Centers
state: Florida
city: Miami Lakes
country: United States
facility: Inpatient Research Clinical LLC
state: Florida
city: Miami Lakes
country: United States
facility: RM Medical Research Inc
state: Florida
city: Miami
country: United States
facility: Infinite Clinical Research
state: Florida
city: Miami
country: United States
facility: A&A Research Group Inc
state: Florida
city: Miramar
country: United States
facility: Eminat LLC
state: Florida
city: Naples
country: United States
facility: Advanced Research for Health Improvement LLC
state: Florida
city: Ocala
country: United States
facility: Ocala Cardiovascular Research
state: Florida
city: Oviedo
country: United States
facility: Oviedo Medical Research
state: Florida
city: Palm Springs
country: United States
facility: CTMD Research
state: Florida
city: Pembroke Pines
country: United States
facility: Broward Research Center
state: Florida
city: Pensacola
country: United States
facility: SEC Clinical Research
state: Florida
city: Port Charlotte
country: United States
facility: Peace River Cardiovascular Center
state: Florida
city: Saint Petersburg
country: United States
facility: Advanced Medical Research Center
state: Florida
city: Tampa
country: United States
facility: New Tampa Health
state: Florida
city: Tampa
country: United States
facility: James A Haley Veterans Hospital
state: Florida
city: Tampa
country: United States
facility: BayCare Medical Group Inc
state: Florida
city: Tampa
country: United States
facility: Genesis Clinical Research
state: Florida
city: Tampa
country: United States
facility: BayCare Health System
state: Florida
city: Tampa
country: United States
facility: Ravessa Clinical Research
state: Florida
city: Wellington
country: United States
facility: Cardiology Partners Clinical Research Institute
state: Florida
city: Fayetteville
country: United States
facility: Javara Research
state: Georgia
city: Gainesville
country: United States
facility: Northeast Georgia Medical Center
state: Georgia
city: Peachtree Corners
country: United States
facility: Alta Pharmaceutical Research Center
state: Georgia
city: Tucker
country: United States
facility: Atlanta Heart Specialists LLC
state: Georgia
city: Meridian
country: United States
facility: Solaris Clinical Research
state: Idaho
city: Nampa
country: United States
facility: Saltzer Health
state: Idaho
city: Addison
country: United States
facility: Biofortis Research
state: Illinois
city: Arlington Heights
country: United States
facility: Northwest Heart Clinical Rsrch LLC
state: Illinois
city: Chicago
country: United States
facility: Cedar Crosse Research Ct
state: Illinois
city: Chicago
country: United States
facility: Chicago Clinical Research Inst
state: Illinois
city: Jerseyville
country: United States
facility: Gateway Cardiology PC
state: Illinois
city: Peoria
country: United States
facility: Methodist Med Center Of Illinois
state: Illinois
city: Springfield
country: United States
facility: SIU School of Medicine
state: Illinois
city: Springfield
country: United States
facility: Prairie Heart Institute
state: Illinois
city: Elkhart
country: United States
facility: Elkhart Cardiology Group
state: Indiana
city: Indianapolis
country: United States
facility: Franciscan Health Services Research Center
state: Indiana
city: Lebanon
country: United States
facility: Witham Health Services
state: Indiana
city: Merrillville
country: United States
facility: The Heart Center of Lake County
state: Indiana
city: Munster
country: United States
facility: Cardiovascular Research Of Northwest Indiana, Llc
state: Indiana
city: Waterloo
country: United States
facility: Covenant Medical Center
state: Iowa
city: Kansas City
country: United States
facility: University of Kansas Hospital
state: Kansas
city: Overland Park
country: United States
facility: Midwest Heart and Vascular Spec
state: Kansas
city: Topeka
country: United States
facility: Cotton O Neil Clinical Res Center
state: Kansas
city: Wichita
country: United States
facility: Ascension Via Christi Research
state: Kansas
city: Lexington
country: United States
facility: University of Kentucky College of Health Sciences
state: Kentucky
city: Louisville
country: United States
facility: U of Louisville Rudd Heart and Lung
state: Kentucky
city: Alexandria
country: United States
facility: Christus Health Central Lousia
state: Louisiana
city: Baton Rouge
country: United States
facility: Louisiana Cardiology Associates
state: Louisiana
city: Bossier City
country: United States
facility: Grace Research LLC
state: Louisiana
city: Covington
country: United States
facility: Cardiovascular Associates Research
state: Louisiana
city: Covington
country: United States
facility: Louisiana Heart Center Research
state: Louisiana
city: Crowley
country: United States
facility: Avant Research Associates LLC
state: Louisiana
city: Eunice
country: United States
facility: Horizon Research Group of Opelousas, LLC
state: Louisiana
city: Gray
country: United States
facility: Cardiovascular Institute South ASC
state: Louisiana
city: Hammond
country: United States
facility: Heart Clinic of Hammond
state: Louisiana
city: Lafayette
country: United States
facility: CV Ins of the South
state: Louisiana
city: Mandeville
country: United States
facility: North Shore Heart and Vascular
state: Louisiana
city: Mandeville
country: United States
facility: Clinical Trials Management LLC
state: Louisiana
city: Metairie
country: United States
facility: Omega Clinical Research
state: Louisiana
city: Monroe
country: United States
facility: Clinical Trials of America LA LLC
state: Louisiana
city: Natchitoches
country: United States
facility: Barnum Medical Research Inc
state: Louisiana
city: New Orleans
country: United States
facility: Crescent City Physicians Inc
state: Louisiana
city: Opelousas
country: United States
facility: CV Ins of the South
state: Louisiana
city: Shreveport
country: United States
facility: Grace Research Llc
state: Louisiana
city: Slidell
country: United States
facility: Louisiana Heart Center Research
state: Louisiana
city: Zachary
country: United States
facility: Southern Clinical Research
state: Louisiana
city: Baltimore
country: United States
facility: Sinai Ct for Throm Res and Drug Dev
state: Maryland
city: Beltsville
country: United States
facility: Metropolitan Cardiovascular Consultants Llc
state: Maryland
city: Columbia
country: United States
facility: Johns Hopkins University
state: Maryland
city: Fort Washington
country: United States
facility: Anderson Medical Research
state: Maryland
city: Glenn Dale
country: United States
facility: Javara Inc
state: Maryland
city: Lanham
country: United States
facility: Capitol Cardiology Associates
state: Maryland
city: Oxon Hill
country: United States
facility: MD Medical Research
state: Maryland
city: Rockville
country: United States
facility: Adventist HealthCare Shady Grove Medical Center
state: Maryland
city: Salisbury
country: United States
facility: Tidal Health Peninsula Regional Inc
state: Maryland
city: Boston
country: United States
facility: Tufts Medical Center
state: Massachusetts
city: Boston
country: United States
facility: Dana Farber Cancer Institute
state: Massachusetts
city: Boston
country: United States
facility: VA Boston Healthcare System
state: Massachusetts
city: Boston
country: United States
facility: Beth Israel Deaconess Medical Center
state: Massachusetts
city: Methuen
country: United States
facility: ActivMed Practices and Research
state: Massachusetts
city: Detroit
country: United States
facility: Henry Ford Hospital
state: Michigan
city: Flint
country: United States
facility: AA Medical Research Center
state: Michigan
city: Grand Rapids
country: United States
facility: Healthy Heart Cardiology
state: Michigan
city: Lansing
country: United States
facility: McLaren Greater Lansing
state: Michigan
city: Midland
country: United States
facility: MyMichigan Medical Center Midland
state: Michigan
city: Saginaw
country: United States
facility: Central University Of Michigan
state: Michigan
city: Southfield
country: United States
facility: Providence Hospital Patient Care Research
state: Michigan
city: Traverse City
country: United States
facility: Traverse Heart and Vascular
state: Michigan
city: Ypsilanti
country: United States
facility: Trinity Health Michigan Heart
state: Michigan
city: Duluth
country: United States
facility: St Marys Medical Center
state: Minnesota
city: Minneapolis
country: United States
facility: University Of Minnesota
state: Minnesota
city: Robbinsdale
country: United States
facility: North Memorial Heart and Vascular Institute
state: Minnesota
city: Saint Cloud
country: United States
facility: CentraCare Heart and Vascular Center
state: Minnesota
city: Saint Paul
country: United States
facility: Regions Hospital
state: Minnesota
city: Belzoni
country: United States
facility: Belzoni Clinical Research
state: Mississippi
city: Jackson
country: United States
facility: Jackson Heart Clinic
state: Mississippi
city: Jackson
country: United States
facility: VAMC Research-G V Sonny Montgomery Clinic
state: Mississippi
city: Tupelo
country: United States
facility: Cardiology Associates of North MS
state: Mississippi
city: Yazoo City
country: United States
facility: Yazoo Clinical Research .
state: Mississippi
city: Kansas City
country: United States
facility: Kansas City VA Medical Center
state: Missouri
city: North Kansas City
country: United States
facility: North Kansas City Hospital
state: Missouri
city: Saint Louis
country: United States
facility: St Louis V A Medical Center
state: Missouri
city: Saint Louis
country: United States
facility: Gateway Cardiovascular Rsch Ctr Inc
state: Missouri
city: Saint Louis
country: United States
facility: Mercy South
state: Missouri
city: Saint Louis
country: United States
facility: St Louis Heart and Vascular
state: Missouri
city: Springfield
country: United States
facility: Mercy Hospital
state: Missouri
city: Lincoln
country: United States
facility: Physician Research Collaboration
state: Nebraska
city: Omaha
country: United States
facility: VA Medical Center - NWI, Endocrine Studies (R151)
state: Nebraska
city: Omaha
country: United States
facility: CCT Research
state: Nebraska
city: Henderson
country: United States
facility: Las Vegas Endocrinology
state: Nevada
city: Las Vegas
country: United States
facility: AB Clinical Trials
state: Nevada
city: Las Vegas
country: United States
facility: Clinical Research of South Nevada
state: Nevada
city: Manchester
country: United States
facility: Catholic Medical Center
state: New Hampshire
city: Haddon Heights
country: United States
facility: Cooper University Health Care
state: New Jersey
city: Linden
country: United States
facility: New Jersey Heart
state: New Jersey
city: Manalapan
country: United States
facility: Garden State Heart Care
state: New Jersey
city: New Brunswick
country: United States
facility: Robert Wood Johnson Medical School
state: New Jersey
city: Newark
country: United States
facility: Newark Beth Israel Medical Center
state: New Jersey
city: Ridgewood
country: United States
facility: The Valley Hospital
state: New Jersey
city: Somerset
country: United States
facility: Cardio Metabolic Institute
state: New Jersey
city: Albuquerque
country: United States
facility: New Mexico Heart Institute
state: New Mexico
city: Albany
country: United States
facility: Albany Medical College
state: New York
city: Binghamton
country: United States
facility: Meridian Clinical Research
state: New York
city: Cooperstown
country: United States
facility: Bassett Medical Center
state: New York
city: Endwell
country: United States
facility: Meridian Clinical Research LLC
state: New York
city: Mineola
country: United States
facility: NYU Langone Hlth Card Assoc
state: New York
city: New York
country: United States
facility: Weill Cornell Medical Center
state: New York
city: New York
country: United States
facility: Icahn School of Med at Mt Sinai
state: New York
city: Northport
country: United States
facility: Northport VA Medical Center
state: New York
city: Rochester
country: United States
facility: Rochester Clinical Research
state: New York
city: Stony Brook
country: United States
facility: State Uni of NY at Stony Brook
state: New York
city: Valhalla
country: United States
facility: Westchester Medical Center
state: New York
city: Charlotte
country: United States
facility: Novant Health Heart and Vascular Institute
state: North Carolina
city: Charlotte
country: United States
facility: Tryon Medical Partners PLLC
state: North Carolina
city: Morehead City
country: United States
facility: Lucas Research
state: North Carolina
city: Raleigh
country: United States
facility: NC Heart and Vascular Research LLC
state: North Carolina
city: Salisbury
country: United States
facility: Accellacare
state: North Carolina
city: Winston-Salem
country: United States
facility: Wake Forest University Baptist Medical Center
state: North Carolina
city: Grand Forks
country: United States
facility: Altru Health Research Dept.
state: North Dakota
city: Akron
country: United States
facility: Akron Hospital Summa Health System
state: Ohio
city: Cincinnati
country: United States
facility: Velocity Clin Research Springdale
state: Ohio
city: Cincinnati
country: United States
facility: University Of Cincinnati
state: Ohio
city: Cleveland
country: United States
facility: University Hospitals Cleveland Medical Center
state: Ohio
city: Kettering
country: United States
facility: Kettering Medical Center
state: Ohio
city: Marion
country: United States
facility: Rama Research LLC
state: Ohio
city: Springfield
country: United States
facility: Heart House Research Foundation
state: Ohio
city: Toledo
country: United States
facility: Mercy Health St Vincent Med Ctr
state: Ohio
city: Vandalia
country: United States
facility: Premier Cardiovascular Institute
state: Ohio
city: Tulsa
country: United States
facility: Oklahoma Heart Institute
state: Oklahoma
city: Bend
country: United States
facility: Bend Memorial Clinic
state: Oregon
city: Corvallis
country: United States
facility: Samaritan Cardiology
state: Oregon
city: Abington
country: United States
facility: Abington Memorial Hospital
state: Pennsylvania
city: Butler
country: United States
facility: Butler Memorial Hospital
state: Pennsylvania
city: Pittsburgh
country: United States
facility: UPMC
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Preferred Primary Care Physicians
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Preferred Primary Care Physicians
state: Pennsylvania
city: Smithfield
country: United States
facility: Frontier Clinical Research LLC
state: Pennsylvania
city: Warwick
country: United States
facility: Kent County Memorial Hospital
state: Rhode Island
city: Charleston
country: United States
facility: Medical Univ Of South Carolina
state: South Carolina
city: Columbia
country: United States
facility: Columbia Heart Clinic
state: South Carolina
city: Columbia
country: United States
facility: Columbia VA Health Care System
state: South Carolina
city: Greenville
country: United States
facility: Bon Secours Medical Group
state: South Carolina
city: Greenville
country: United States
facility: Prisma Health Upstate
state: South Carolina
city: Ladson
country: United States
facility: Trident Cardiology
state: South Carolina
city: Myrtle Beach
country: United States
facility: Family Medicine of Sayebrook
state: South Carolina
city: Sioux Falls
country: United States
facility: Sanford University of South Dakota Medical Center
state: South Dakota
city: Sioux Falls
country: United States
facility: North Central Heart
state: South Dakota
city: Greenville
country: United States
facility: Wellmont CVA Heart Institute
state: Tennessee
city: Jackson
country: United States
facility: Apex Cardiology Research Associates of Jackson
state: Tennessee
city: Jackson
country: United States
facility: The Jackson Clinic PA
state: Tennessee
city: Knoxville
country: United States
facility: Accellacare
state: Tennessee
city: Knoxville
country: United States
facility: Turkey Creek Medical Center
state: Tennessee
city: Memphis
country: United States
facility: Memphis Cardiology and Vein Ct
state: Tennessee
city: Powell
country: United States
facility: Cardiovascular Res of Knoxville LLC
state: Tennessee
city: Tullahoma
country: United States
facility: Tennessee Center For Clinical Trials
state: Tennessee
city: Amarillo
country: United States
facility: PharmaTex Research LLC
state: Texas
city: Bedford
country: United States
facility: North Hills Medical Research Inc
state: Texas
city: Dallas
country: United States
facility: VA North Texas Health Care System
state: Texas
city: Dallas
country: United States
facility: Soltero Cardiovascular Research Center
state: Texas
city: Dallas
country: United States
facility: North Texas Endocrine Center
state: Texas
city: Dallas
country: United States
facility: Research Institute of Dallas PA
state: Texas
city: Dallas
country: United States
facility: Texas Health Physicians Group
state: Texas
city: Dallas
country: United States
facility: SW Family Medicine Associates
state: Texas
city: El Paso
country: United States
facility: David Turbay MD PLLC
state: Texas
city: Fort Worth
country: United States
facility: Texas Health Physicians Group
state: Texas
city: Fort Worth
country: United States
facility: Texas Health Physicians Group
state: Texas
city: Houston
country: United States
facility: Houston Methodist Hospital
state: Texas
city: Houston
country: United States
facility: UT Physicians Memorial Hermann
state: Texas
city: Houston
country: United States
facility: Orion Medical
state: Texas
city: Houston
country: United States
facility: Village Medical Village MD S Tx
state: Texas
city: Lampasas
country: United States
facility: FMC Science
state: Texas
city: Livingston
country: United States
facility: East Texas Research Associates Inc.
state: Texas
city: McKinney
country: United States
facility: CardioVoyage LLC
state: Texas
city: Pflugerville
country: United States
facility: Discovery Clinical Trials
state: Texas
city: Plano
country: United States
facility: Heartplace-Plano
state: Texas
city: San Antonio
country: United States
facility: University of Texas Health Science Ctr
state: Texas
city: San Antonio
country: United States
facility: South Texas Cardiovascular Consultants PLLC
state: Texas
city: San Antonio
country: United States
facility: Endeavor Clinical Trials
state: Texas
city: Sherman
country: United States
facility: Sherman Clinical Research
state: Texas
city: Stephenville
country: United States
facility: Javara Research
state: Texas
city: Sugar Land
country: United States
facility: Privia Medical Group Gulf Coast
state: Texas
city: Texas City
country: United States
facility: Alina clinical trials .
state: Texas
city: Texas City
country: United States
facility: Alina clinical trials Baxter REsearch LLC
state: Texas
city: The Woodlands
country: United States
facility: Javara Research
state: Texas
city: Bountiful
country: United States
facility: Progressive Clinical Research
state: Utah
city: Burke
country: United States
facility: Burke Internal Medicine and Research
state: Virginia
city: Forest
country: United States
facility: Javara Research
state: Virginia
city: Hopewell
country: United States
facility: Heart Care Associates P C
state: Virginia
city: Norfolk
country: United States
facility: York Clinical Research
state: Virginia
city: Richmond
country: United States
facility: Dominion Medical Associates
state: Virginia
city: Roanoke
country: United States
facility: Roanoke Heart Institute
state: Virginia
city: Winchester
country: United States
facility: Winchester Medical Center
state: Virginia
city: Seattle
country: United States
facility: Virginia Mason Medical Centre
state: Washington
city: Seattle
country: United States
facility: Swedish Medical Center-Cardiovascular Research
state: Washington
city: Seattle
country: United States
facility: University of Washington
state: Washington
city: Tacoma
country: United States
facility: Universal Research Group LLC
state: Washington
city: Wenatchee
country: United States
facility: Confluence Health Hospital
state: Washington
city: Caba
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Caba
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Caba
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Caba
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Caba
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Ciudad Autonoma de Bs As
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Mar del Plata
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Quilmes
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Ramos Mejia
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: San Martin
country: Argentina
facility: Novartis Investigative Site
state: Buenos Aires
city: Posadas
country: Argentina
facility: Novartis Investigative Site
state: Misiones
city: Ciudad de Salta
country: Argentina
facility: Novartis Investigative Site
state: Provincia De Salta
city: Tucuman
country: Argentina
facility: Novartis Investigative Site
state: San Miguel De Tucuman
city: Rosario
country: Argentina
facility: Novartis Investigative Site
state: Santa Fe
city: Rosario
country: Argentina
facility: Novartis Investigative Site
state: Santa Fe
city: Rosario
country: Argentina
facility: Novartis Investigative Site
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city: San Miguel de Tucuman
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facility: Novartis Investigative Site
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country: Argentina
facility: Novartis Investigative Site
city: Buenos Aires
country: Argentina
facility: Novartis Investigative Site
city: Buenos Aires
country: Argentina
facility: Novartis Investigative Site
city: Caba
country: Argentina
facility: Novartis Investigative Site
city: Ciudad de Buenos Aires
country: Argentina
facility: Novartis Investigative Site
city: Cordoba
country: Argentina
facility: Novartis Investigative Site
city: Cordoba
country: Argentina
facility: Novartis Investigative Site
city: Corrientes
country: Argentina
facility: Novartis Investigative Site
city: Formosa
country: Argentina
facility: Novartis Investigative Site
city: Mendoza
country: Argentina
facility: Novartis Investigative Site
city: Santa Fe
country: Argentina
facility: Novartis Investigative Site
city: Santa Fe
country: Argentina
facility: Novartis Investigative Site
city: Botany
country: Australia
facility: Novartis Investigative Site
state: New South Wales
city: New Lambton Heights
country: Australia
facility: Novartis Investigative Site
state: New South Wales
city: Auchenflower
country: Australia
facility: Novartis Investigative Site
state: Queensland
city: Bundaberg West
country: Australia
facility: Novartis Investigative Site
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city: Milton
country: Australia
facility: Novartis Investigative Site
state: Queensland
city: Woolloongabba
country: Australia
facility: Novartis Investigative Site
state: Queensland
city: Adelaide
country: Australia
facility: Novartis Investigative Site
state: South Australia
city: Bedford Park
country: Australia
facility: Novartis Investigative Site
state: South Australia
city: Leabrook
country: Australia
facility: Novartis Investigative Site
state: South Australia
city: Woodville South
country: Australia
facility: Novartis Investigative Site
state: South Australia
city: Clayton
country: Australia
facility: Novartis Investigative Site
state: Victoria
city: Geelong
country: Australia
facility: Novartis Investigative Site
state: Victoria
city: Malvern East
country: Australia
facility: Novartis Investigative Site
state: Victoria
city: Richmond
country: Australia
facility: Novartis Investigative Site
state: Victoria
city: Joondalup
country: Australia
facility: Novartis Investigative Site
state: Western Australia
city: Nedlands
country: Australia
facility: Novartis Investigative Site
state: Western Australia
city: Liverpool
country: Australia
facility: Novartis Investigative Site
city: Braunau
country: Austria
facility: Novartis Investigative Site
city: Graz
country: Austria
facility: Novartis Investigative Site
city: Antwerpen
country: Belgium
facility: Novartis Investigative Site
city: Brasschaat
country: Belgium
facility: Novartis Investigative Site
city: Brugge
country: Belgium
facility: Novartis Investigative Site
city: Bruxelles
country: Belgium
facility: Novartis Investigative Site
city: Charleroi
country: Belgium
facility: Novartis Investigative Site
city: Edegem
country: Belgium
facility: Novartis Investigative Site
city: Genk
country: Belgium
facility: Novartis Investigative Site
city: Gent
country: Belgium
facility: Novartis Investigative Site
city: Kortrijk
country: Belgium
facility: Novartis Investigative Site
city: La Louviere
country: Belgium
facility: Novartis Investigative Site
city: Roeselare
country: Belgium
facility: Novartis Investigative Site
city: Ronse
country: Belgium
facility: Novartis Investigative Site
city: Yvoir
country: Belgium
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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city: Salvador
country: Brazil
facility: Novartis Investigative Site
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city: Brasilia
country: Brazil
facility: Novartis Investigative Site
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city: Brasilia
country: Brazil
facility: Novartis Investigative Site
state: DF
city: Vitoria
country: Brazil
facility: Novartis Investigative Site
state: ES
city: Belo Horizonte
country: Brazil
facility: Novartis Investigative Site
state: MG
city: Uberlandia
country: Brazil
facility: Novartis Investigative Site
state: Minas Gerais
city: Curitiba
country: Brazil
facility: Novartis Investigative Site
state: PR
city: Pelotas
country: Brazil
facility: Novartis Investigative Site
state: RS
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country: Brazil
facility: Novartis Investigative Site
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city: Porto Alegre
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facility: Novartis Investigative Site
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city: Porto Alegre
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facility: Novartis Investigative Site
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city: Blumenau
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facility: Novartis Investigative Site
state: Santa Catarina
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country: Brazil
facility: Novartis Investigative Site
state: Sao Paulo
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country: Brazil
facility: Novartis Investigative Site
state: SE
city: Campinas
country: Brazil
facility: Novartis Investigative Site
state: SP
city: Ribeirao Preto
country: Brazil
facility: Novartis Investigative Site
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city: Santo Andre
country: Brazil
facility: Novartis Investigative Site
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city: Santo Andre
country: Brazil
facility: Novartis Investigative Site
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city: Sao Bernardo do Campo
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facility: Novartis Investigative Site
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city: Sao Jose Do Rio Preto
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facility: Novartis Investigative Site
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city: Sao Jose do Rio Preto
country: Brazil
facility: Novartis Investigative Site
state: SP
city: Sao Paulo
country: Brazil
facility: Novartis Investigative Site
state: SP
city: Sao Paulo
country: Brazil
facility: Novartis Investigative Site
state: SP
city: Sao Paulo
country: Brazil
facility: Novartis Investigative Site
state: SP
city: Sao Paulo
country: Brazil
facility: Novartis Investigative Site
state: SP
city: Campinas
country: Brazil
facility: Novartis Investigative Site
city: Rio de Janeiro
country: Brazil
facility: Novartis Investigative Site
city: Sao Jose
country: Brazil
facility: Novartis Investigative Site
city: Sao Paulo
country: Brazil
facility: Novartis Investigative Site
city: Sandanski
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facility: Novartis Investigative Site
state: Blagoevgrad
city: Burgas
country: Bulgaria
facility: Novartis Investigative Site
city: Haskovo
country: Bulgaria
facility: Novartis Investigative Site
city: Kyustendil
country: Bulgaria
facility: Novartis Investigative Site
city: Montana
country: Bulgaria
facility: Novartis Investigative Site
city: Pernik
country: Bulgaria
facility: Novartis Investigative Site
city: Pleven
country: Bulgaria
facility: Novartis Investigative Site
city: Plovdiv
country: Bulgaria
facility: Novartis Investigative Site
city: Ruse
country: Bulgaria
facility: Novartis Investigative Site
city: Ruse
country: Bulgaria
facility: Novartis Investigative Site
city: Sliven
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Sofia
country: Bulgaria
facility: Novartis Investigative Site
city: Stamboliyski
country: Bulgaria
facility: Novartis Investigative Site
city: Stara Zagora
country: Bulgaria
facility: Novartis Investigative Site
city: Stara Zagora
country: Bulgaria
facility: Novartis Investigative Site
city: Veliko Tarnovo
country: Bulgaria
facility: Novartis Investigative Site
city: Calgary
country: Canada
facility: Novartis Investigative Site
state: Alberta
city: Edmonton
country: Canada
facility: Novartis Investigative Site
state: Alberta
city: Edmonton
country: Canada
facility: Novartis Investigative Site
state: Alberta
city: North Vancouver
country: Canada
facility: Novartis Investigative Site
state: British Columbia
city: Vancouver
country: Canada
facility: Novartis Investigative Site
state: British Columbia
city: Vancouver
country: Canada
facility: Novartis Investigative Site
state: British Columbia
city: Victoria
country: Canada
facility: Novartis Investigative Site
state: British Columbia
city: Victoria
country: Canada
facility: Novartis Investigative Site
state: British Columbia
city: Victoria
country: Canada
facility: Novartis Investigative Site
state: British Columbia
city: Winnipeg
country: Canada
facility: Novartis Investigative Site
state: Manitoba
city: Winnipeg
country: Canada
facility: Novartis Investigative Site
state: Manitoba
city: Moncton
country: Canada
facility: Novartis Investigative Site
state: New Brunswick
city: Halifax
country: Canada
facility: Novartis Investigative Site
state: Nova Scotia
city: Sydney
country: Canada
facility: Novartis Investigative Site
state: Nova Scotia
city: Cambridge
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Guelph
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Newmarket
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Oakville
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Peterborough
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Sarnia
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Scarborough
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Scarborough
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Stoufville
country: Canada
facility: Novartis Investigative Site
state: Ontario
city: Greenfield Park
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Montreal
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Montreal
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Montreal
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Sainte Foy
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Sainte Foy
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: St Jerome
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Terrebonne
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Trois Rivieres
country: Canada
facility: Novartis Investigative Site
state: Quebec
city: Quebec
country: Canada
facility: Novartis Investigative Site
city: Quebec
country: Canada
facility: Novartis Investigative Site
city: Victoria
country: Chile
facility: Novartis Investigative Site
state: Araucania
city: Osorno
country: Chile
facility: Novartis Investigative Site
state: Los Lagos
city: La Serena
country: Chile
facility: Novartis Investigative Site
state: Region De Coquimbo
city: Temuco
country: Chile
facility: Novartis Investigative Site
state: Region De La Araucania
city: Santiago
country: Chile
facility: Novartis Investigative Site
state: Region Metropolitana
city: Santiago
country: Chile
facility: Novartis Investigative Site
state: RM
city: Vina Del Mar
country: Chile
facility: Novartis Investigative Site
state: Valparaiso
city: Santiago
country: Chile
facility: Novartis Investigative Site
city: Santiago
country: Chile
facility: Novartis Investigative Site
city: Foshan
country: China
facility: Novartis Investigative Site
state: Guangdong
city: Guangzhou City
country: China
facility: Novartis Investigative Site
state: Guangdong
city: Guangzhou
country: China
facility: Novartis Investigative Site
state: Guangdong
city: Guangzhou
country: China
facility: Novartis Investigative Site
state: Guangdong
city: Nanning
country: China
facility: Novartis Investigative Site
state: Guangxi
city: Harbin
country: China
facility: Novartis Investigative Site
state: Heilongjiang
city: Jingzhou
country: China
facility: Novartis Investigative Site
state: Hubei
city: Wuhan
country: China
facility: Novartis Investigative Site
state: Hubei
city: Wuhan
country: China
facility: Novartis Investigative Site
state: Hubei
city: Wuhan
country: China
facility: Novartis Investigative Site
state: Hubei
city: Changsha
country: China
facility: Novartis Investigative Site
state: Hunan
city: Changsha
country: China
facility: Novartis Investigative Site
state: Hunan
city: Hohhot
country: China
facility: Novartis Investigative Site
state: Inner Mongolia
city: Changzhou
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Jiangyin
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Nanjing
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Nanjing
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Nanjing
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Suzhou
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Xuzhou
country: China
facility: Novartis Investigative Site
state: Jiangsu
city: Nanchang
country: China
facility: Novartis Investigative Site
state: Jiangxi
city: Pingxiang
country: China
facility: Novartis Investigative Site
state: Jiangxi
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country: China
facility: Novartis Investigative Site
state: Jilin
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country: China
facility: Novartis Investigative Site
state: Liaoning
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country: China
facility: Novartis Investigative Site
state: Liaoning
city: Jinan
country: China
facility: Novartis Investigative Site
state: Shandong
city: Shanghai
country: China
facility: Novartis Investigative Site
state: Shanghai
city: Taiyuan
country: China
facility: Novartis Investigative Site
state: Shanxi
city: Xian
country: China
facility: Novartis Investigative Site
state: Shanxi
city: Chengdu
country: China
facility: Novartis Investigative Site
state: Sichuan
city: Tianjin
country: China
facility: Novartis Investigative Site
state: Tianjin
city: Urumqi
country: China
facility: Novartis Investigative Site
state: Xinjiang
city: Wulumuqi
country: China
facility: Novartis Investigative Site
state: Xinjiang
city: Hangzhou
country: China
facility: Novartis Investigative Site
state: Zhejiang
city: Lishui City
country: China
facility: Novartis Investigative Site
state: Zhejiang
city: Taizhou
country: China
facility: Novartis Investigative Site
state: Zhejiang
city: Beijing
country: China
facility: Novartis Investigative Site
city: Beijing
country: China
facility: Novartis Investigative Site
city: Beijing
country: China
facility: Novartis Investigative Site
city: Beijing
country: China
facility: Novartis Investigative Site
city: Beijing
country: China
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Guangzhou
country: China
facility: Novartis Investigative Site
city: Jinan
country: China
facility: Novartis Investigative Site
city: Shanghai
country: China
facility: Novartis Investigative Site
city: Shanghai
country: China
facility: Novartis Investigative Site
city: Shanghai
country: China
facility: Novartis Investigative Site
city: Tianjin
country: China
facility: Novartis Investigative Site
city: Xiamen
country: China
facility: Novartis Investigative Site
city: Medellin
country: Colombia
facility: Novartis Investigative Site
state: Antioquia
city: Medellin
country: Colombia
facility: Novartis Investigative Site
state: Antioquia
city: Barranquilla
country: Colombia
facility: Novartis Investigative Site
state: Atlantico
city: Cartagena
country: Colombia
facility: Novartis Investigative Site
state: Bolivar
city: Manizales
country: Colombia
facility: Novartis Investigative Site
state: Caldas
city: Pereira
country: Colombia
facility: Novartis Investigative Site
state: Risaralda
city: Cali
country: Colombia
facility: Novartis Investigative Site
state: Valle Del Cauca
city: Cali
country: Colombia
facility: Novartis Investigative Site
state: Valle Del Cauca
city: Barranquilla
country: Colombia
facility: Novartis Investigative Site
city: Bogota
country: Colombia
facility: Novartis Investigative Site
city: Cali
country: Colombia
facility: Novartis Investigative Site
city: Floridablanca
country: Colombia
facility: Novartis Investigative Site
city: Cakovec
country: Croatia
facility: Novartis Investigative Site
city: Krapinske toplice
country: Croatia
facility: Novartis Investigative Site
city: Opatija
country: Croatia
facility: Novartis Investigative Site
city: Osijek
country: Croatia
facility: Novartis Investigative Site
city: Rijeka
country: Croatia
facility: Novartis Investigative Site
city: Slavonski Brod
country: Croatia
facility: Novartis Investigative Site
city: Split
country: Croatia
facility: Novartis Investigative Site
city: Zagreb
country: Croatia
facility: Novartis Investigative Site
city: Cesky Krumlov
country: Czechia
facility: Novartis Investigative Site
state: Czech Republic
city: Louny
country: Czechia
facility: Novartis Investigative Site
state: Czech Republic
city: Slany
country: Czechia
facility: Novartis Investigative Site
state: Czech Republic
city: Hradec Kralove
country: Czechia
facility: Novartis Investigative Site
state: CZE
city: Policska
country: Czechia
facility: Novartis Investigative Site
state: CZE
city: Bedihost
country: Czechia
facility: Novartis Investigative Site
city: Brno Bohunice
country: Czechia
facility: Novartis Investigative Site
city: Brno
country: Czechia
facility: Novartis Investigative Site
city: Brno
country: Czechia
facility: Novartis Investigative Site
city: Hodonin
country: Czechia
facility: Novartis Investigative Site
city: JIhlava
country: Czechia
facility: Novartis Investigative Site
city: Marianske lazne
country: Czechia
facility: Novartis Investigative Site
city: Nachod
country: Czechia
facility: Novartis Investigative Site
city: Ostrava
country: Czechia
facility: Novartis Investigative Site
city: Ostrava
country: Czechia
facility: Novartis Investigative Site
city: Ostrava
country: Czechia
facility: Novartis Investigative Site
city: Pardubice
country: Czechia
facility: Novartis Investigative Site
city: Praha 10
country: Czechia
facility: Novartis Investigative Site
city: Praha 5
country: Czechia
facility: Novartis Investigative Site
city: Praha
country: Czechia
facility: Novartis Investigative Site
city: Prerov
country: Czechia
facility: Novartis Investigative Site
city: Pribram VIII
country: Czechia
facility: Novartis Investigative Site
city: Svitavy
country: Czechia
facility: Novartis Investigative Site
city: Trebic
country: Czechia
facility: Novartis Investigative Site
city: Uherske Hradiste
country: Czechia
facility: Novartis Investigative Site
city: Zlin
country: Czechia
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Central Jutland
city: Aarhus N
country: Denmark
facility: Novartis Investigative Site
city: Esbjerg
country: Denmark
facility: Novartis Investigative Site
city: Glostrup
country: Denmark
facility: Novartis Investigative Site
city: Herlev
country: Denmark
facility: Novartis Investigative Site
city: Hjorring
country: Denmark
facility: Novartis Investigative Site
city: Roskilde
country: Denmark
facility: Novartis Investigative Site
city: Svendborg
country: Denmark
facility: Novartis Investigative Site
city: Viborg
country: Denmark
facility: Novartis Investigative Site
city: Parnu
country: Estonia
facility: Novartis Investigative Site
city: Tallinn
country: Estonia
facility: Novartis Investigative Site
city: Tallinn
country: Estonia
facility: Novartis Investigative Site
city: Tallinn
country: Estonia
facility: Novartis Investigative Site
city: Tallinn
country: Estonia
facility: Novartis Investigative Site
city: Tartu
country: Estonia
facility: Novartis Investigative Site
city: Tartu
country: Estonia
facility: Novartis Investigative Site
city: Kuopio
country: Finland
facility: Novartis Investigative Site
state: Pohjois Savo
city: Helsinki
country: Finland
facility: Novartis Investigative Site
city: Jyvaskyla
country: Finland
facility: Novartis Investigative Site
city: Turku
country: Finland
facility: Novartis Investigative Site
city: Turku
country: Finland
facility: Novartis Investigative Site
city: Nice
country: France
facility: Novartis Investigative Site
state: Cedex1
city: Limoges
country: France
facility: Novartis Investigative Site
state: Haute Vienne
city: Amiens
country: France
facility: Novartis Investigative Site
city: Beziers Cedex
country: France
facility: Novartis Investigative Site
city: Brest
country: France
facility: Novartis Investigative Site
city: Chambray les Tours
country: France
facility: Novartis Investigative Site
city: Cholet
country: France
facility: Novartis Investigative Site
city: Clermont-Ferrand Cedex 1
country: France
facility: Novartis Investigative Site
city: Corbeil Essonnes
country: France
facility: Novartis Investigative Site
city: Grenoble
country: France
facility: Novartis Investigative Site
city: Le Coudray
country: France
facility: Novartis Investigative Site
city: Lille
country: France
facility: Novartis Investigative Site
city: Lille
country: France
facility: Novartis Investigative Site
city: Marseille
country: France
facility: Novartis Investigative Site
city: Marseille
country: France
facility: Novartis Investigative Site
city: Metz
country: France
facility: Novartis Investigative Site
city: Montauban
country: France
facility: Novartis Investigative Site
city: Montpellier
country: France
facility: Novartis Investigative Site
city: Nimes
country: France
facility: Novartis Investigative Site
city: Orleans
country: France
facility: Novartis Investigative Site
city: Paris cedex 10
country: France
facility: Novartis Investigative Site
city: Paris
country: France
facility: Novartis Investigative Site
city: Paris
country: France
facility: Novartis Investigative Site
city: Paris
country: France
facility: Novartis Investigative Site
city: Pau
country: France
facility: Novartis Investigative Site
city: Pessac
country: France
facility: Novartis Investigative Site
city: Poitiers
country: France
facility: Novartis Investigative Site
city: Reims
country: France
facility: Novartis Investigative Site
city: Rennes
country: France
facility: Novartis Investigative Site
city: Toulouse 4
country: France
facility: Novartis Investigative Site
city: Tourcoing
country: France
facility: Novartis Investigative Site
city: Valenciennes
country: France
facility: Novartis Investigative Site
city: Ioannina
country: Greece
facility: Novartis Investigative Site
state: GR
city: Larissa
country: Greece
facility: Novartis Investigative Site
state: GR
city: Athens
country: Greece
facility: Novartis Investigative Site
city: Athens
country: Greece
facility: Novartis Investigative Site
city: Athens
country: Greece
facility: Novartis Investigative Site
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country: Greece
facility: Novartis Investigative Site
city: Oroshaza
country: Hungary
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Hungary
facility: Novartis Investigative Site
city: Balassagyarmat
country: Hungary
facility: Novartis Investigative Site
city: Balatonfured
country: Hungary
facility: Novartis Investigative Site
city: Budapest
country: Hungary
facility: Novartis Investigative Site
city: Budapest
country: Hungary
facility: Novartis Investigative Site
city: Debrecen
country: Hungary
facility: Novartis Investigative Site
city: Kalocsa
country: Hungary
facility: Novartis Investigative Site
city: Kecskemet
country: Hungary
facility: Novartis Investigative Site
city: Kistarcsa
country: Hungary
facility: Novartis Investigative Site
city: Komarom
country: Hungary
facility: Novartis Investigative Site
city: Nagykanizsa
country: Hungary
facility: Novartis Investigative Site
city: Oroshaza
country: Hungary
facility: Novartis Investigative Site
city: Pecs
country: Hungary
facility: Novartis Investigative Site
city: Szeged
country: Hungary
facility: Novartis Investigative Site
city: Szekszard
country: Hungary
facility: Novartis Investigative Site
city: Szolnok
country: Hungary
facility: Novartis Investigative Site
city: Zalaegerszeg
country: Hungary
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Iceland
facility: Novartis Investigative Site
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country: India
facility: Novartis Investigative Site
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country: India
facility: Novartis Investigative Site
state: Andhrapradesh
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facility: Novartis Investigative Site
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country: India
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Gujarat
city: Ahmedabad
country: India
facility: Novartis Investigative Site
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country: India
facility: Novartis Investigative Site
state: Gujarat
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Karnataka
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: India
facility: Novartis Investigative Site
state: Kerala
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country: India
facility: Novartis Investigative Site
state: Madhyapradesh
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facility: Novartis Investigative Site
state: Maharashtra
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facility: Novartis Investigative Site
state: Maharashtra
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country: India
facility: Novartis Investigative Site
state: Maharashtra
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facility: Novartis Investigative Site
state: Maharashtra
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country: India
facility: Novartis Investigative Site
state: Maharashtra
city: Pune
country: India
facility: Novartis Investigative Site
state: Maharashtra
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facility: Novartis Investigative Site
state: Rajasthan
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facility: Novartis Investigative Site
state: Tamil Nadu
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country: India
facility: Novartis Investigative Site
state: Tamil Nadu
city: Madurai
country: India
facility: Novartis Investigative Site
state: Tamil Nadu
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country: India
facility: Novartis Investigative Site
state: Telangana
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country: India
facility: Novartis Investigative Site
state: Telangana
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country: India
facility: Novartis Investigative Site
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country: India
facility: Novartis Investigative Site
state: Uttar Pradesh
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country: India
facility: Novartis Investigative Site
state: Uttar Pradesh
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facility: Novartis Investigative Site
state: Uttar Pradesh
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country: India
facility: Novartis Investigative Site
state: Uttar Pradesh
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country: India
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Uttarakhand
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country: India
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Coimbatore
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facility: Novartis Investigative Site
city: New Delhi
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facility: Novartis Investigative Site
city: New Delhi
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facility: Novartis Investigative Site
city: Puducherry
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facility: Novartis Investigative Site
city: Ashdod
country: Israel
facility: Novartis Investigative Site
city: Holon
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facility: Novartis Investigative Site
city: Jerusalem
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facility: Novartis Investigative Site
city: Nahariya
country: Israel
facility: Novartis Investigative Site
city: Petach Tikva
country: Israel
facility: Novartis Investigative Site
city: Ramat Gan
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facility: Novartis Investigative Site
city: Sefad
country: Israel
facility: Novartis Investigative Site
city: Zerifin
country: Israel
facility: Novartis Investigative Site
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country: Italy
facility: Novartis Investigative Site
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country: Italy
facility: Novartis Investigative Site
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country: Italy
facility: Novartis Investigative Site
state: BS
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country: Italy
facility: Novartis Investigative Site
state: FE
city: Firenze
country: Italy
facility: Novartis Investigative Site
state: FI
city: Grosseto
country: Italy
facility: Novartis Investigative Site
state: GR
city: Pozzilli
country: Italy
facility: Novartis Investigative Site
state: IS
city: Milano
country: Italy
facility: Novartis Investigative Site
state: MI
city: Milano
country: Italy
facility: Novartis Investigative Site
state: MI
city: Milano
country: Italy
facility: Novartis Investigative Site
state: MI
city: Rozzano
country: Italy
facility: Novartis Investigative Site
state: MI
city: Modena
country: Italy
facility: Novartis Investigative Site
state: MO
city: Pordenone
country: Italy
facility: Novartis Investigative Site
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country: Italy
facility: Novartis Investigative Site
state: SI
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facility: Novartis Investigative Site
state: TO
city: Sassari
country: Italy
facility: Novartis Investigative Site
city: Toyota
country: Japan
facility: Novartis Investigative Site
state: Aichi
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country: Japan
facility: Novartis Investigative Site
state: Fukuka
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country: Japan
facility: Novartis Investigative Site
state: Ishikawa
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facility: Novartis Investigative Site
state: Ishikawa
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Osaka
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facility: Novartis Investigative Site
state: Saitama
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facility: Novartis Investigative Site
city: Nairobi
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facility: Novartis Investigative Site
city: Cheongju si
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facility: Novartis Investigative Site
state: Chungcheongbuk Do
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facility: Novartis Investigative Site
state: Dalseo Gu
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facility: Novartis Investigative Site
state: Gangwon-Do
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country: Korea, Republic of
facility: Novartis Investigative Site
state: Gyeonggi Do
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country: Korea, Republic of
facility: Novartis Investigative Site
state: Gyeongsangnam Do
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country: Korea, Republic of
facility: Novartis Investigative Site
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city: Seoul
country: Korea, Republic of
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Seocho Gu
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country: Korea, Republic of
facility: Novartis Investigative Site
city: Daejeon
country: Korea, Republic of
facility: Novartis Investigative Site
city: Gwangju
country: Korea, Republic of
facility: Novartis Investigative Site
city: Incheon
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facility: Novartis Investigative Site
city: Jinju
country: Korea, Republic of
facility: Novartis Investigative Site
city: Seoul
country: Korea, Republic of
facility: Novartis Investigative Site
city: Seoul
country: Korea, Republic of
facility: Novartis Investigative Site
city: Seoul
country: Korea, Republic of
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facility: Novartis Investigative Site
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country: Latvia
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Panevezys
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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city: Solferino Phoenix
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city: Ciudad de Mexico
country: Mexico
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Jalisco
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Mexico
facility: Novartis Investigative Site
state: Yucatan
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country: Mexico
facility: Novartis Investigative Site
city: Aguascalientes
country: Mexico
facility: Novartis Investigative Site
city: Chihuahua
country: Mexico
facility: Novartis Investigative Site
city: Durango
country: Mexico
facility: Novartis Investigative Site
city: Guadalajara
country: Mexico
facility: Novartis Investigative Site
city: Xalapa
country: Mexico
facility: Novartis Investigative Site
city: Xalapa
country: Mexico
facility: Novartis Investigative Site
city: Doetinchem
country: Netherlands
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Amersfoort
country: Netherlands
facility: Novartis Investigative Site
city: Amstelveen
country: Netherlands
facility: Novartis Investigative Site
city: Amsterdam
country: Netherlands
facility: Novartis Investigative Site
city: Amsterdam
country: Netherlands
facility: Novartis Investigative Site
city: Deventer
country: Netherlands
facility: Novartis Investigative Site
city: Dordrecht
country: Netherlands
facility: Novartis Investigative Site
city: Gouda
country: Netherlands
facility: Novartis Investigative Site
city: Groningen
country: Netherlands
facility: Novartis Investigative Site
city: Groningen
country: Netherlands
facility: Novartis Investigative Site
city: Heemstede
country: Netherlands
facility: Novartis Investigative Site
city: Leeuwarden
country: Netherlands
facility: Novartis Investigative Site
city: Leiderdorp
country: Netherlands
facility: Novartis Investigative Site
city: Meppel
country: Netherlands
facility: Novartis Investigative Site
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country: Netherlands
facility: Novartis Investigative Site
city: Nijmegen
country: Netherlands
facility: Novartis Investigative Site
city: Sneek
country: Netherlands
facility: Novartis Investigative Site
city: Tiel
country: Netherlands
facility: Novartis Investigative Site
city: Tilburg
country: Netherlands
facility: Novartis Investigative Site
city: Venlo
country: Netherlands
facility: Novartis Investigative Site
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city: Christchurch
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facility: Novartis Investigative Site
city: Christchurch
country: New Zealand
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: New Zealand
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Oslo
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facility: Novartis Investigative Site
city: Skedsmokorset
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Philippines
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Philippines
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Bialystok
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Torun
country: Poland
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
city: Warszawa
country: Poland
facility: Novartis Investigative Site
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country: Poland
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Portugal
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Portugal
facility: Novartis Investigative Site
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country: Puerto Rico
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Romania
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Serbia
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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country: Serbia
facility: Novartis Investigative Site
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country: Serbia
facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
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facility: Novartis Investigative Site
state: Centurion
city: Bloemfontein
country: South Africa
facility: Novartis Investigative Site
state: Free State
city: Germiston
country: South Africa
facility: Novartis Investigative Site
state: Gauteng
city: Pretoria
country: South Africa
facility: Novartis Investigative Site
state: Gauteng
city: Pretoria
country: South Africa
facility: Novartis Investigative Site
state: Gauteng
city: Soweto
country: South Africa
facility: Novartis Investigative Site
state: Gauteng
city: Vereeniging
country: South Africa
facility: Novartis Investigative Site
state: Gauteng
city: Cape Town
country: South Africa
facility: Novartis Investigative Site
state: Western Cape
city: Cape Town
country: South Africa
facility: Novartis Investigative Site
state: Western Cape
city: George
country: South Africa
facility: Novartis Investigative Site
state: Western Cape
city: Paarl
country: South Africa
facility: Novartis Investigative Site
state: Western Cape
city: Cape Town
country: South Africa
facility: Novartis Investigative Site
state: ZAF
city: Bloemfontein
country: South Africa
facility: Novartis Investigative Site
city: Cape Town
country: South Africa
facility: Novartis Investigative Site
city: Midrand
country: South Africa
facility: Novartis Investigative Site
city: Pretoria
country: South Africa
facility: Novartis Investigative Site
city: Worcester
country: South Africa
facility: Novartis Investigative Site
city: Ferrol
country: Spain
facility: Novartis Investigative Site
state: A Coruna
city: Almeria
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: Cordoba
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: Malaga
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: Sevilla
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: Sevilla
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: Sevilla
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: Utrera
country: Spain
facility: Novartis Investigative Site
state: Andalucia
city: El Prat de Llobregat
country: Spain
facility: Novartis Investigative Site
state: Barcelona
city: Hospitalet de Llobregat
country: Spain
facility: Novartis Investigative Site
state: Barcelona
city: Sabadell
country: Spain
facility: Novartis Investigative Site
state: Barcelona
city: Sant Joan Despi
country: Spain
facility: Novartis Investigative Site
state: Barcelona
city: Jerez
country: Spain
facility: Novartis Investigative Site
state: Cadiz
city: Villamartin
country: Spain
facility: Novartis Investigative Site
state: Cadiz
city: Santander
country: Spain
facility: Novartis Investigative Site
state: Cantabria
city: Salamanca
country: Spain
facility: Novartis Investigative Site
state: Castilla Y Leon
city: Valladolid
country: Spain
facility: Novartis Investigative Site
state: Castilla Y Leon
city: Barcelona
country: Spain
facility: Novartis Investigative Site
state: Cataluna
city: Reus
country: Spain
facility: Novartis Investigative Site
state: Cataluna
city: Barcelona
country: Spain
facility: Novartis Investigative Site
state: Catalunya
city: Barcelona
country: Spain
facility: Novartis Investigative Site
state: Catalunya
city: Valencia
country: Spain
facility: Novartis Investigative Site
state: Comunidad Valenciana
city: Valencia
country: Spain
facility: Novartis Investigative Site
state: Comunidad Valenciana
city: A Coruna
country: Spain
facility: Novartis Investigative Site
state: Galicia
city: La Coruna
country: Spain
facility: Novartis Investigative Site
state: Galicia
city: Santiago De Compostela
country: Spain
facility: Novartis Investigative Site
state: Galicia
city: Mallorca
country: Spain
facility: Novartis Investigative Site
state: Islas Baleares
city: Palma De Mallorca
country: Spain
facility: Novartis Investigative Site
state: Islas Baleares
city: Alcorcon
country: Spain
facility: Novartis Investigative Site
state: Madrid
city: San Sebastian de los Reyes
country: Spain
facility: Novartis Investigative Site
state: Madrid
city: El Palmar
country: Spain
facility: Novartis Investigative Site
state: Murcia
city: Bilbao
country: Spain
facility: Novartis Investigative Site
state: Pais Vasco
city: Vigo
country: Spain
facility: Novartis Investigative Site
state: Pontevedra
city: A Coruna
country: Spain
facility: Novartis Investigative Site
city: Alicante
country: Spain
facility: Novartis Investigative Site
city: Barcelona
country: Spain
facility: Novartis Investigative Site
city: Barcelona
country: Spain
facility: Novartis Investigative Site
city: Granada
country: Spain
facility: Novartis Investigative Site
city: Huelva
country: Spain
facility: Novartis Investigative Site
city: Las Palmas de Gran Canaria
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Madrid
country: Spain
facility: Novartis Investigative Site
city: Salamanca
country: Spain
facility: Novartis Investigative Site
city: Zaragoza
country: Spain
facility: Novartis Investigative Site
city: Stockholm
country: Sweden
facility: Novartis Investigative Site
state: SE
city: Goteborg
country: Sweden
facility: Novartis Investigative Site
state: Vastra Gotalands Lan
city: Falun
country: Sweden
facility: Novartis Investigative Site
city: Goteborg
country: Sweden
facility: Novartis Investigative Site
city: Lund
country: Sweden
facility: Novartis Investigative Site
city: Malmo
country: Sweden
facility: Novartis Investigative Site
city: Stockholm
country: Sweden
facility: Novartis Investigative Site
city: Stockholm
country: Sweden
facility: Novartis Investigative Site
city: Vasteras
country: Sweden
facility: Novartis Investigative Site
city: Kaohsiung
country: Taiwan
facility: Novartis Investigative Site
city: Tainan
country: Taiwan
facility: Novartis Investigative Site
city: Tainan
country: Taiwan
facility: Novartis Investigative Site
city: Taipei
country: Taiwan
facility: Novartis Investigative Site
city: Taipei
country: Taiwan
facility: Novartis Investigative Site
city: Taipei
country: Taiwan
facility: Novartis Investigative Site
city: Taipei
country: Taiwan
facility: Novartis Investigative Site
city: Songkhla
country: Thailand
facility: Novartis Investigative Site
state: Hat Yai
city: Bangkok
country: Thailand
facility: Novartis Investigative Site
city: Bangkok
country: Thailand
facility: Novartis Investigative Site
city: Chiang Mai
country: Thailand
facility: Novartis Investigative Site
city: Muang
country: Thailand
facility: Novartis Investigative Site
city: Muang
country: Thailand
facility: Novartis Investigative Site
city: Istanbul
country: Turkey
facility: Novartis Investigative Site
state: TUR
city: Adana
country: Turkey
facility: Novartis Investigative Site
city: Ankara
country: Turkey
facility: Novartis Investigative Site
city: Bakırkoy Istanbul
country: Turkey
facility: Novartis Investigative Site
city: Bursa
country: Turkey
facility: Novartis Investigative Site
city: Diskapi Ankara
country: Turkey
facility: Novartis Investigative Site
city: Istanbul
country: Turkey
facility: Novartis Investigative Site
city: Istanbul
country: Turkey
facility: Novartis Investigative Site
city: Izmir
country: Turkey
facility: Novartis Investigative Site
city: Konya
country: Turkey
facility: Novartis Investigative Site
Study officials:
affiliation: Novartis Pharmaceuticals
name: Novartis Pharmaceuticals
role: STUDY_DIRECTOR
References: