Clinical trial NCT06577480: Validity and Reliability of the Turkish Version of the Post-Liver Transplant Quality of Life Questionnaire
Official title: Investigation of Validity and Reliability of the Turkish Version of the Post-Liver Transplant Quality of Life (pLTQ) Questionnaire
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Liver Transplant Disorder
Quality of Life
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2024-08-29
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Liver transplant recipients

Brief summary: Liver transplantation is a crucial treatment for life-threatening liver diseases, including acute liver failure, end-stage chronic liver disease, primary liver cancers, and congenital metabolic disorders. Quality of life in liver transplant patients is vital. The World Health Organization defines quality of life as an individual's perception of their position in life within the context of culture, values, goals, and expectations. Liver transplantation improves quality of life. Recipients should be closely monitored and supported psychologically, with the effectiveness of the intervention in improving quality of life well-documented. Saab et al. developed the post-Liver Transplantation Quality of Life (pLTQ) questionnaire, which includes eight sub-dimensions across 32 items. To our knowledge, no Turkish-specific QoL tool for liver transplant patients currently exists. This study aims to validate and assess the reliability of the Turkish version of the pLTQ questionnaire.


Eligibility criteria: Inclusion criteria:

* Being 18 years of age or older,
* Having received post-liver transplant treatment at Hacettepe University Adult Hospital General Surgery Units and being referred to Hacettepe University, Faculty of Physical Therapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit after routine clinical and laboratory examinations, if deemed appropriate for the study,
* Being willing to participate in the study.

Exclusion criteria:

* Having undergone combined liver-kidney transplantation and multiple organ transplantation,
* Having uncontrolled cardiovascular and neurological problems,
* Having a cognitive problem that will prevent understanding the questionnaires,
* Not being willing to participate in the study.

Primary outcomes:
measure: Assessment of quality of life - disease specific
timeFrame: 1st day
measure: Assessment of quality of life - general
timeFrame: 1st day
measure: Assessment of health profile
timeFrame: 1st day
measure: Psychosocial status assessment
timeFrame: 1st day
measure: Fatigue assessment
timeFrame: 1st day
Secondary outcomes:
measure: Anthropometric and clinical characteristics
timeFrame: 1st day
measure: Model for End-Stage Liver Disease score index
timeFrame: 1st day
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University Faculty of Physical Therapy and Rehabilitation
Study officials:
affiliation: Hacettepe University
name: Aslihan Cakmak-Onal, PhD, PT
role: PRINCIPAL_INVESTIGATOR
affiliation: Hacettepe University
name: Naciye Vardar-Yagli, PhD, PT
role: STUDY_DIRECTOR
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