Clinical trial NCT06848985: Impact of Combined Aerobic and Resistance Exercise on Autonomic Function and Cardiopulmonary Endurance in Obese College Students
Official title: Impact of Combined Aerobic and Resistance Exercise on Autonomic Function and Cardiopulmonary Endurance in Obese College Students
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Obese College Students
Aerobic Exercise Combined with Resistance Exercise
Keywords: Aerobic exercise combined with resistance exercises
Cardiorespiratory endurance
Autonomic function
Obese college students
Lead sponsor: Capital University of Physical Education and Sports, China
Sponsor class: OTHER
First posted: 2025-02-27
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 22
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Obese college students aged 18-22 were recruited from a university in Beijing to participate in a public elective course on exercise for weight loss and slimming at the Capital University of Physical Education and Sport (CUPES). Ultimately, 60 students who met these criteria were selected for the study, divided into an experimental group of 30 and a control group of 30. The study primarily utilized a combined exercise regimen of aerobic and resistance exercises, conducted three times a week over a period of 16 weeks. The control group maintained their normal physical activity levels without any additional intervention.
Primary purpose: TREATMENT

Brief summary: This study explores the potential link between aerobic exercise combined with resistance training and improvements in cardiopulmonary function in obese individuals, focusing particularly on the influence of autonomic nerve function. By examining the effects of combined exercise on obese college students, this research aims to elucidate the critical role that autonomic nerve function improvement plays in enhancing cardiopulmonary function in this demographic.

The study primarily utilized a combined exercise regimen of aerobic and resistance exercises, conducted three times a week over a period of 16 weeks. One session was held during class hours, with the remaining two sessions scheduled during free time in the university gym. Aerobic exercises included the use of treadmills and elliptical machines, with intensity maintained at 60%-70% of the maximum heart rate (calculated as 220 minus age), for a total of 40 minutes per session (5 minutes of warm-up, 30 minutes of main exercise, and 5 minutes of cool-down). Heart rate monitors were used to ensure the intensity was maintained; resistance exercises involved gym equipment and bodyweight exercises, including the use of a pec deck machine, lat pull-downs, chest presses, bicep curls, tricep extensions, leg curls, and leg presses. The intensity of resistance exercises was set at about 65%-70% of one repetition maximum (1RM), with each session consisting of three sets of 6-8 repetitions and lasting for 30 minutes.


Eligibility criteria: Inclusion Criteria:

* Obese college students aged 18-22 were recruited from a university in Beijing to participate in a public elective course on exercise for weight loss and slimming at the Capital University of Physical Education and Sport (CUPES). The inclusion criteria included a BMI of ≥28 kg/m\^2, no history of chronic diseases such as cardiovascular or metabolic diseases, no psychiatric conditions (e.g., depression, anxiety disorder, obsessive-compulsive disorder), and no physical disabilities or movement disorders (such as bone and joint diseases).

Exclusion Criteria:

* The exclusion criteria include individuals with diseases that may affect training (such as cardiovascular diseases, respiratory diseases, and musculoskeletal disorders), as well as those diagnosed with mental disorders (such as depression, anxiety, obsessive-compulsive disorder, etc.).

Primary outcomes:
measure: Autonomic function
timeFrame: From enrollment to the end of treatment at 16 weeks
measure: Cardiorespiratory endurance
timeFrame: From enrollment to the end of treatment at 16 weeks
Secondary outcomes:
measure: The Functional Movement Screen (FMS) score
timeFrame: From enrollment to the end of treatment at 16 weeks
measure: Body composition
timeFrame: From enrollment to the end of treatment at 16 weeks
Other outcomes:
Locations:
city: Beijing
country: China
facility: Capital University Of Physical Education And Sports
state: Beijing
Study officials:
References: