Clinical trial NCT04839796: Northeastern Taiwan Community Medicine Research Cohort
Official title: A Cohort Study on Disease Prevention and Health Promotion in Northeastern Region of Taiwan
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Cohort Study
Keywords: NTCMRC
Maintenance Project
Health Care Activities
Lead sponsor: Chang Gung Memorial Hospital
Sponsor class: OTHER
First posted: 2021-04-09
Enrollment: 20000
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Participants who enroll in these community health activities and meet the following conditions:

1. Over the age of 20.
2. Residing in 64 administrative areas in Keelung city and new Taipei city.

Brief summary: The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age of 20 residing in 64 administrative areas in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires, and disease awareness seminars.

Biological samples, questionnaire information, and medical data obtained from researcher's participants are stored in researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.

Detailed description: The cohort study on disease prevention and health promotion in the northeastern region of Taiwan is a trial dedicated to large-scale generational research in northeastern Taiwan beginning in the August of 2013. The program aims to develop a comprehensive and integrated approach to disease prevention and community health. The researcher's cohort organizes healthcare outreaches for participants over the age in Keelung city and new Taipei city. The researcher's sessions include a comprehensive health examination, health-related questionnaires and disease awareness seminars.

Biological samples, questionnaire information, and medical data obtained from the researcher's participants are stored in the researcher's core laboratory. Depersonalized data and samples are shared with partnering trials approved by the Chang Gung Memorial Hospital Institutional review board. The investigators are currently partnered with 18 clinical trials spanning across multiple disciplines such as urology, hepatology, metabolism, physical therapy, and psychology.

The investigators are also a member of the national "Establish Multi-omics Database of Smart Healthcare for Obesity Therapeutics involving " joint project and the national "Remote Medical Monitoring System-Linking Healthcare Industrial Ecosystem-Taiwanese Novel Disease Monitoring Solution" initiative.

Introduction: This research is conducted in the form of community health care activities. Through regular community health household activities, community residents' awareness of health is improved, and various pathogenic factors are analyzed to strengthen health education, improve living habits, reduce risk factors, and promote the health of community residents.

Project purpose: In order to promote community fitness, The investigators will conduct long-term community medicine generation research. This research consists of a series of collaborative projects such as chronic kidney disease, chronic liver disease, metabolic syndrome, depression, dementia, obesity, exercise rehabilitation, etc.

In community health care activities, collect biological samples such as blood, urine, feces, etc., as well as questionnaire data. This project will link participants relevant health data to establish a database for the generation of Keelung Chang Gung community medicine research. These data will be provided for analysis of co-operative plans related to generations of research and long-term tracking of participants health.

Eligibility criteria: Inclusion Criteria:

1. Residing in Keelung city and new Taipei city.
2. Mobile health and mental health
3. Participating in healthcare outreaches

Exclusion Criteria:

1. Under 20 years old
2. Participant without judgment
3. Participant has HIV

Primary outcomes:
measure: Participant died during the observation period.
timeFrame: From 2013 Augus to Feb 2021
measure: Dementia
timeFrame: From 2013 Augus to Feb 2021
measure: Chronic Kidney Disease
timeFrame: From 2013 Augus to Feb 2021
measure: Liver cancer
timeFrame: From 2013 Augus to Feb 2021
Secondary outcomes:
Other outcomes:
Locations:
city: Keelung
country: Taiwan
facility: Community Medicine Research Center Chang Gung Memorial Hospital Keelung,Taiwan,204
Study officials:
affiliation: Community Medicine Research Center,Chang Gung Memorial Hospital,Keelung branch
name: Yu Chiau Shyu, PHD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Wu IW, Tsai TH, Lo CJ, Chou YJ, Yeh CH, Cheng ML, Lai CC, Sytwu HK, Tsai TF. Discovery of a Biomarker Signature That Reveals a Molecular Mechanism Underlying Diabetic Kidney Disease via Organ Cross Talk. Diabetes Care. 2022 Jun 2;45(6):e102-e104. doi: 10.2337/dc22-0145. No abstract available.