Clinical trial NCT06359457: Correlation Between Serum Progesterone Level And Primary Dysmenorrhea
Official title: Correlation Between Serum Progesterone Level And Menstrual Symptoms In Young Females With Primary Dysmenorrhea
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Primary Dysmenorrhea
Keywords: Dysmenorrhoea
Serum progesterone level
Visual analogue scale
Menstrual symptoms questionnaire
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2024-04-11
Enrollment: 100
Sex: FEMALE
Minimum age (years): 17
Maximum age (years): 25
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: One hundred girls with dysmenorrhoea. Menarche at least 3 years ago. All females should be regular menstrual cycles.

Brief summary: This study will be conducted to determine the correlation between the levels of serum progesterone and Menstrual Symptoms In Young Females with primary dysmenorrhea.

Detailed description: One hundred adult females with primary dysmenorrhea will participate in this study. They will be recruited from the Gynaecological outpatient clinic, Kasr El Ainy University Hospital, Cairo, Egypt Many studies reported that primary dysmenorrhea was the result of increased prostaglandin, especially prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) which produced the effect through the cyclooxygenase pathway, and further led to uterine ischemia hypoxia. Nevertheless the relationship between the serum progesterone level and menstrual symptoms was not completely clear. Hence, this study will investigate the association between the serum progesterone level and menstrual symptoms in young females with primaryf dysmenorrhea.

Eligibility criteria: Inclusion Criteria:

1. One hundreds adult females were suffered from primary dysmenorrhea.
2. Their age was ranged from 17 to 24 years.
3. Their body mass index was ranged from 20 to 25 kg/m2.

Exclusion Criteria:

* Any participant will be excluded from the study if they have:

  1. Irregulars or infrequent menstrual cycles.
  2. Pacemaker, Myasthenia gravis, hyperthyroidism, active tuberculosis and psychosis.
  3. Pelvic pathology.

Primary outcomes:
measure: Serum progesterone level
timeFrame: 1 month
measure: Pain intensity
timeFrame: 1 month
measure: Physical and psychological menstrual symptoms
timeFrame: 1 month
measure: Correlation between serum progesterone level and pain
timeFrame: 1 month
measure: Correlation between serum progesterone level and menstrual symptoms
timeFrame: 1 month
Secondary outcomes:
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Menna Allah Youssef Nasr El-Dien
Study officials:
affiliation: Lecturer of Physical Therapy for Orthopedic. Physical Therapy, Nahda University.
name: HANAA HAFEZ, PhD
role: STUDY_DIRECTOR
affiliation: Lecturer of Physical Therapy for Basic Science. Physical Therapy, Nahda University.
name: RANIA Hamed, PhD
role: STUDY_DIRECTOR
affiliation: Lecturer Of Physical Therapy For Cardiovascular, Respiratory and Geriatrics.
name: ESRAA MOHAMED, PhD
role: STUDY_DIRECTOR
affiliation: Faculty of Medicine, Al-Azhar University.
name: HOSSAM HUSSIEN, PhD
role: STUDY_DIRECTOR
References: