Clinical trial NCT06370286: The Effect of Acute Concurrent Exercise on Inhibitory Control: An Event-related Potential Study
Official title: The Effect of Acute Concurrent Exercise on Inhibitory Control: An Event-related Potential Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Exercise
Cognition
Lead sponsor: National Taiwan Normal University
Sponsor class: OTHER
First posted: 2024-04-17
Enrollment: 78
Sex: ALL
Minimum age (years): 20
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Participants were randomly assigned to either a concurrent exercise (CE), aerobic exercise (AE), or control (CON) group. Participants in the CE group engaged in 12-minutes of AE (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). The AE group participated in 25 minutes of AE (40%-59% HRR). Prior to and following exercise onset, participants in both the CE and AE groups completed a 5-minute warm-up and cool-down. Participants in the CON group read books for 35 minutes. Lactate concentrations were measured at timepoint of 0-, 17-, and 30-minutes relative to the treatment onset. Response time (RT) and accuracy in the Stroop test, as well as P3 amplitudes, were assessed before and after the treatment.
Primary purpose: TREATMENT

Brief summary: The present study aimed to determine the effects of acute concurrent exercise on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate among younger adults. The main questions it aims to answer are: (1) Does acute concurrent exercise improve inhibitory control via behavioral and event-related potential approaches? (2) Does lactate play a potential mediational role in the effect of acute concurrent exercise on inhibitory control?

Detailed description: The present study aimed to determine the effects of acute concurrent exercise (CE) on inhibitory control via behavioral and event-related potential approaches and to examine its potential mediational role on lactate. Participants were randomly assigned to either a CE, aerobic exercise (AE), or control (CON) group. Participants in the CE group engaged in 12-minutes of AE (40%-59% of heart rate reserve \[HRR\]) coupled with 13-minutes of resistance exercise (1 set, with 75% of 10-repetition maximum, and 12 repetitions of 8 movements). The AE group participated in 25 minutes of AE (40%-59% HRR). Prior to and following exercise onset, participants in both the CE and AE groups completed a 5-minute warm-up and cool-down. Participants in the CON group read books for 35 minutes. Lactate concentrations were measured at timepoint of 0-, 17-, and 30-minutes relative to the treatment onset. Response time (RT) and accuracy in the Stroop test, as well as P3 amplitudes, were assessed before and after the treatment.

Eligibility criteria: Inclusion Criteria:

* aged between 20 and 30 years
* able to exercise without undue risk (i.e., the first seven questions of the Physical Activity Readiness Questionnaire for Everyone \[PAR-Q+\] were answered "No")
* right-handed dominance
* typical or corrected-to-typical eyesight
* limited physical activity in the previous month (i.e., \< 150 minutes/week of moderate-intensity physical activity)

Exclusion Criteria:

* psychiatric or neurological ailments
* cardiorespiratory or neuromuscular conditions
* obese status (body mass index \[BMI\] \> 27 kg/m2)

Primary outcomes:
measure: Inhibitory control
timeFrame: 30 minutes
Secondary outcomes:
measure: Blood lactate
timeFrame: Timepoint 1 (prior to the commencement of treatment), Timepoint 2 (17 minutes after the initiation of treatment), and Timepoint 3 (30 minutes after the start of treatment).
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Department of Physical Education and Sport Sciences, National Taiwan Normal University
Study officials:
affiliation: Department of Physical Education and Sport Sciences, National Taiwan Normal University
name: Yu-Kai Chang, PhD
role: STUDY_CHAIR
affiliation: Department of Physical Education and Sport Sciences, National Taiwan Normal University
name: Ruei-Hong Li, MS
role: PRINCIPAL_INVESTIGATOR
References: