Clinical trial NCT03360149: Health Practice of Hemophilia Patiente Care During Pregnancy, Delivery and Newborn Children
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hemophilia
Keywords: Hemophilia pregnant
Hemophilia delivery
Hemophilia children
Lead sponsor: University Hospital, Brest
Sponsor class: OTHER
First posted: 2017-12-04
Enrollment: 35
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: - Adult with Hemophilia A or B during Pregnancy, Delivery and Newborn Children

Brief summary: Prenancy and specialy delivery for hemophilia mother and her children possibly hemophilia is risked.

Diagnostical of hemophilia pregnan is the first difficulty but patients with hemorrhagic menstruation without etiology known, hemorrhagic complication during a chirurgical procedure or during previously pregnancy currently are examine in Haemostasis consultation.

None French recommendation specifie for health practice of these hemophilia patients exists. However, Anglo-Saxon recommendations are published in 2011.

The objective of this study is to realize a French investigation of health practice about hemophilia care of these patients and to compare them with the English reference table.


Eligibility criteria: Inclusion Criteria:

* Adult
* Hemophilia A or B
* Pregnancy between 2014 and 2016

Exclusion Criteria:

- Opposition

Primary outcomes:
measure: antenatal care in pregnant women carriers of hemophilia
timeFrame: during pregnancy
measure: labour and delivery procedures
timeFrame: day of delivery
measure: post-partum care
timeFrame: day of delivery until 3 month
measure: children care
timeFrame: day of delivery until 3 month
measure: antenatal care in pregnant women carriers of hemophilia
timeFrame: 9 month (during pregnancy)
measure: antenatal care in pregnant women carriers of hemophilia
timeFrame: 9 month (during pregnancy)
measure: labour and delivery procedures
timeFrame: day of delivery
measure: labour and delivery procedures
timeFrame: day of delivery
measure: labour and delivery procedures
timeFrame: day of delivery
measure: post-partum care
timeFrame: day of delivery until 3 month
measure: post-partum care
timeFrame: day of delivery until 3 month
measure: post-partum care
timeFrame: day of delivery until 3 month
measure: children care
timeFrame: day of delivery until 3 month
measure: children care
timeFrame: day of delivery until 3 month
Secondary outcomes:
Other outcomes:
Locations:
city: Angers
country: France
facility: CHU d'Angers
city: Brest
country: France
facility: CHRU de Brest
city: Le Mans
country: France
facility: Ch Le Mans
city: Nantes
country: France
facility: CHU de Nantes
city: Poitiers
country: France
facility: CHU de Poitiers
city: Rennes
country: France
facility: CHU de Rennes
city: Tours
country: France
facility: CHU de TOURS
Study officials:
References:
citation: Nau A, Gillet B, Guillet B, Beurrier P, Ardillon L, Cussac V, Guillou S, Raj L, Trossaert M, Horvais V, Bayart S, Potin J, Rose J, Macchi L, Couturaud F, Lacut K, Pan-Petesch B. Bleeding complications during pregnancy and delivery in haemophilia carriers and their neonates in Western France: An observational study. Haemophilia. 2020 Nov;26(6):1046-1055. doi: 10.1111/hae.14117. Epub 2020 Aug 25.