Clinical trial NCT04601896: Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018
Official title: Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Refractory Cardiac Arrest
ExtraCorporeal Membrane Oxygenation (ECMO)
Keywords: ExtraCorporeal Membrane Oxygenation (ECMO)
Refractory Cardiac Arrest
Quality life assessement (SF36 QUESTIONNAIRE)
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
First posted: 2020-10-26
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: monocentric study based on clinical data and quality of life assessement,

Retrospective step :

* Clinical data collection for live patients admissed for Refractory Cardiac Arrest with ECMO from january 2006 through december 2018,
* Clinical data collection for live patients admissed for Refractory Cardiac Arrest without ECMO from january 2015 through december 2018,

Prospective step:

* Quality of life assessment via telephone interview based on SF36 questionnaire performed for live patients admissed for Refractory Cardiac Arrest with ECMO from january 2006 through december 2018
* Quality of life assessment via telephone interview based on SF36 questionnaire performed for live patients admissed for Refractory Cardiac Arrest without ECMO from january 2015 through december 2018

Brief summary: If the ExtraCorporeal Membrane Oxygenation (ECMO) improves survival in the management of refractory cardiac arrest (RCA), this technique is still an invasive technique, not devoid of complications and requiring intensive care that can have serious consequences for patients. If the studies so far show an acceptable quality of life post ECMO in refractory cardiac arrest, the study looks about the quality of life of our patients in Grenoble who survived a refractory cardiac arrest between 2006 and 2018 at the hospital university Grenoble Alps and the factors influencing this quality of life.


Eligibility criteria: Inclusion Criteria:

* Adult \>18 years
* Admission to intensive care unit after a Refractory Cardiac Arrest
* Hemodynamic instability after resumption of spontaneous cardiac activity.
* Non-opposition of the patient or his relatives
* Admission to intensive care unit From 2006 Through 2018

Exclusion Criteria:

* ECMO for hypothermia or drug intoxication.
* Comorbidity contraindicated the ECMO
* Patients dead before hospital discharge

Primary outcomes:
measure: Global quality of life score
timeFrame: Through study completion, an average of 3 months
Secondary outcomes:
measure: Live patients characteristics description
timeFrame: Through study completion, an average of 3 months
measure: Vital status
timeFrame: Through study completion, an average of 3 months
measure: Quality of life score related at live patients characteristics description
timeFrame: Through study completion, an average of 3 months
measure: Quality of life score comparison
timeFrame: Through study completion, an average of 3 months
Other outcomes:
Locations:
city: Grenoble
country: France
facility: Chu Grenoble Alpes
Study officials:
References: