Clinical trial NCT03520816: The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience
Official title: The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Burns
Physiotherapy
Exercises
Keywords: Fibronectin
Prealbumin
Physiotherapy
Major Burns
biochemical parameters
Lead sponsor: Hasan Kalyoncu University
Sponsor class: OTHER
First posted: 2018-05-11
Enrollment: 20
Sex: ALL
Minimum age (years): 21
Maximum age (years): 47
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients.

Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study. Participants were divided into two groups: one group was the treatment group and the other was the control group. In the treatment group, patients were admitted to the physiotherapy programme from the first day they have been hospitalised, in addition to their routine treatment (medical, surgery, etc.), for 4 days per week. It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises. The days of treatment were determined as Tuesday, Wednesday, Thursday and Friday. Patients could not be treated on a Monday because that was surgery day. The control group consisted of patients who could not receive physiotherapy due to various reasons. All patients included in the study were evaluated weekly for 6 weeks after admission to the hospital. Parameters such as demographic information, characteristics of burn injury, C-reactive protein, fibronectin, transferrin and prealbumin were evaluated.


Eligibility criteria: Inclusion Criteria:

* Age ≥ 18 years
* Major burn injury (according to ABA)
* Conscious patients

Exclusion Criteria:

* Inhalation injury
* Various chronic disorders
* Organ dysfunctions

Primary outcomes:
measure: Fibronectin
timeFrame: Changes in fibronectin at 6 weeks later
measure: Prealbumin
timeFrame: Changes in prealbumin at 6 weeks later
measure: C-reactive protein
timeFrame: Changes in C-reactive protein at 6 weeks later
measure: Transferrin
timeFrame: Changes in transferrin at 6 weeks later
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Hasan Kalyoncu University
name: MURAT ALİ ÇINAR, Msc
role: PRINCIPAL_INVESTIGATOR
References:
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