Clinical trial NCT03773341: Causes and Patterns of Anterior Cruciate Ligament Injuries Among Egyptian Population
Official title: Causes and Patterns of ACL Injuries Among Egyptian People
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: ACL Injury
Keywords: ACL injury
non sport causes
Egyptians
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2018-12-12
Enrollment: 500
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Egyptian patients with confirmed ACL injury by clinical and radio logical diagnoses older than 18 years old and younger than 60 years old

Brief summary: The aim of work is to detect the patterns and the causes of ACL injury among Egyptian population and to identify its risk factors. Identify the male to female ratio of injuries in our community. To document the patterns and frequencies of associated injuries

Detailed description: The ACL (Anterior Cruciate ligament) is one of the most frequently injured ligaments of the knee, with a prevalence estimated to be 1 in 3000 in the US (greater than 120000 cases annually). ACL injury frequently affects young, active individuals. It is also frequently associated with other structural injuries in the Knee joint like meniscal tears and multi-ligamentous injuries. ACL injury leads to increased laxity in the knee, predispose the knee to subsequent injuries and early onset osteoarthritis of the knee.

Sports related trauma is the commonest cause of ACL rupture. Females are reported to have 2 to 10-fold higher risk of injury than males playing the same sport. According to previous studies at Assuit University Hospital the impression was that the ACL injuries are more common in males than females. Additionally, non-sports injuries like motor cycle accidents and domestic injuries are expected to be a major cause of ACL rupture, besides sports injuries, among Egyptian population.

Eligibility criteria: Inclusion Criteria:

* Patients with confirmed ACL injury

Exclusion Criteria:

* Patients with ACL injury associated with fracture at the same limb

Primary outcomes:
measure: Patterns of ACL injuries among Egyptian population
timeFrame: one year
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Levine JW, Kiapour AM, Quatman CE, Wordeman SC, Goel VK, Hewett TE, Demetropoulos CK. Clinically relevant injury patterns after an anterior cruciate ligament injury provide insight into injury mechanisms. Am J Sports Med. 2013 Feb;41(2):385-95. doi: 10.1177/0363546512465167. Epub 2012 Nov 9.
citation: Arendt E, Dick R. Knee injury patterns among men and women in collegiate basketball and soccer. NCAA data and review of literature. Am J Sports Med. 1995 Nov-Dec;23(6):694-701. doi: 10.1177/036354659502300611.
citation: Anderson AF, Dome DC, Gautam S, Awh MH, Rennirt GW. Correlation of anthropometric measurements, strength, anterior cruciate ligament size, and intercondylar notch characteristics to sex differences in anterior cruciate ligament tear rates. Am J Sports Med. 2001 Jan-Feb;29(1):58-66. doi: 10.1177/03635465010290011501.