Clinical trial NCT04842734: Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Official title: Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease During the Covid-19 Pandemic
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Alzheimer Disease
Telerehabilitation
Online Physical Exercise
Computerized Cognitive Stimulation
Covid-19 Pandemic
Keywords: Alzheimer's disease
Telerehabilitation
Physical exercise
Computerized Cognitive Stimulation
Covid-19 Pandemic
Cognitive Stimulation
Online physical exercise
Alzheimer disease
Lead sponsor: Yeditepe University
Sponsor class: OTHER
First posted: 2021-04-13
Enrollment: 60
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: It is planned to include 60 individuals diagnosed with AD according to DSM-IV diagnostic criteria by the neurologist. Individuals will be randomly divided into three groups; as the physical exercise group (n=20), physical exercise and cognitive stimulation (n=20) and the control group (n=20) according to inclusion criteria
Primary purpose: TREATMENT

Brief summary: Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the Covid-19 pandemic period.


Eligibility criteria: Inclusion Criteria:

* ≥ 65 years and older
* Diagnosed with AD according to DSM-IV diagnostic criteria by a neurologist,
* MOCA ≥ 13
* Clinical Dementia Rating Scale \< 2
* Having sufficient wireless support or telephone connection where the person lives
* Who gave consent to participate in the study
* No history of any neurological or orthopedic injury that could prevent participation in the study and affect functional mobility.

Exclusion Criteria:

* Geriatric Depression Scale score \> 11
* Various mobility restrictions, musculoskeletal disorders, (wheelchair use, etc.)
* Clinically significant aphasia (must be able to understand the therapist's commands)
* Significant visual or sensory impairment
* MoCA \< 13
* Having a severe musculoskeletal disorder
* Having paralysis
* Impaired balance
* The presence of severe lung and heart disease

Primary outcomes:
measure: Alzheimer's Disease Related Quality of Life Scale
timeFrame: 24 weeks
measure: Montreal Cognitive Assessment Scale
timeFrame: 24 weeks
measure: Berg Balance Scale
timeFrame: 24 weeks
measure: Time up and Go Test
timeFrame: 24 weeks
measure: Sit to Stand Test
timeFrame: 24 weeks
measure: Arm Curl Test
timeFrame: 24 weeks
Secondary outcomes:
measure: Katz Activities of Daily Living Scale
timeFrame: 24 weeks
measure: Lawton Instrumental Activities of Daily Living Scale
timeFrame: 24 weeks
measure: Geriatric Depression Scale (Short Form)
timeFrame: 24 weeks
Other outcomes:
Locations:
city: İstanbul
country: Turkey
facility: Yeditepe University
state: Eyalet/Yerleşke
Study officials:
References: