Clinical trial NCT05367375: Comparison of Removing and Non-removing Patellofemoral Joint Osteophytes Following Medial Unicompartment Knee Arthroplasty
Official title: Does Removing Patellofemoral Joint Osteophytes Reduce Anterior Knee Pain Following Unicompartment Knee Arthroplasty?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Anterior Knee Pain
Keywords: patellofemoral osteophyte
anteromedial osteoarthritis knee
mobile bearing UKA
patellofemoral pain
Lead sponsor: Thammasat University
Sponsor class: OTHER
First posted: 2022-05-10
Enrollment: 90
Sex: ALL
Minimum age (years): 43
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: isolated medial osteoarthritis of the knee

Brief summary: Background: Anterior knee pain (AKP) is a challenge following unicompartmental knee arthroplasty (UKA). Some surgeons remove patellofemoral joint (PFJ) osteophytes to reduce osteophyte impingement and AKP. However, there is evidence that PFJ osteophytes compensate for knee osteoarthritis (OA) by increasing and improving stability and increase contract surface area in knee osteoarthritis. Moreover, when PFJ osteophytes are not removed, some studies report good clinical outcomes. The issue of removing or leaving PFJ osteophytes is controversial.

The objective of this study was to compare AKP following mobile bearing UKA after removing or leaving PFJ osteophytes.

Methods: The prospective non-randomized study included 89 isolated medial osteoarthritis (OA) of knee. They were classified into 2 groups. Group (Gp)1 was removing PFJ osteophytes; consists of 44 knees. Gp2 was non-removing PFJ osteophytes: consists of 45 knees. The patients were follow up and recorded incidence of AKP and VAS for AKP at 6 weeks, 3months, 6 months, 1 year and 2 years. No patients were lost to follow up. The patellar tilt and shift were measured at 6 weeks, 3months, 6months, 1year and 2 years via skyline view radiography. The knee society scores, Oxford knee score, knee injury and osteoarthritis outcome score, forgotten joint score and Kujala scale also were recorede at 6 weeks, 3months, 6months, 1 year and 2 years.

Detailed description: Removing and non-removing osteophyte at patellofemoral joint is controversial topic. The osteophyte may help to reduce load and improve stability of patellofemoral joint. Therefore, the purpose of this study is to compared anterior knee pain between removing and non-removing osteophyte at patellofemoral joint following medial mobile bearing unicompartmental knee arthroplasty

Eligibility criteria: Inclusion Criteria:

* age \> 42 years old
* range of motion \> 90 degrees
* flexion contracture\< 15 degrees
* normal function of anterior cruciate ligament

Exclusion Criteria:

* spontaneous osteonecrosis of the knee
* inflammatory joinr arthritis
* full thickness cartilage loss at lateral compartment

Primary outcomes:
measure: incidence of anterior knee pain
timeFrame: 6 weeks
measure: incidence of anterior knee pain
timeFrame: 3 months
measure: incidence of anterior knee pain
timeFrame: 6 months
measure: incidence of anterior knee pain
timeFrame: 1 year
measure: incidence of anterior knee pain
timeFrame: 2 year
measure: Visual analogue scale for anterior knee pain
timeFrame: 6 weeks
measure: Visual analogue scale for anterior knee pain
timeFrame: 3 months
measure: Visual analogue scale for anterior knee pain
timeFrame: 6 months
measure: Visual analogue scale for anterior knee pain
timeFrame: 1 year
measure: Visual analogue scale for anterior knee pain
timeFrame: 2 years
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
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