Clinical trial NCT04102306: Assessing Motor Imagery Ability of Tongue and Mouth in Subjects With and With no Temporomandibular Disorders
Official title: Assessing Motor Imagery Using the Tongue and Mouth Imagery Questionnaire (TMIQ) in Patients With Temporomandibular Disorder and Healthy Control Subjects: a Reliability and Construct Validity Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Temporomandibular Disorder
Motor Imagery
Keywords: orofacial myotherapies;
physical therapy;
assessment;
questionnaire validation
Lead sponsor: Cabinet de Kinesitherapie SCM Saint-Alexandre
Sponsor class: INDUSTRY
Collaborators: name: University of Lyon
name: Hospices Civils de Lyon
First posted: 2019-09-25
Enrollment: 94
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: 47 participants with DTM 47 participants with no DTM (healthy control) age-matched and gender-matched to participants with DTM.

Brief summary: Temporomandibular disorder (TMD) is the symptomatic expression of a muscular or an articular impairment at the manducatory tract. TMD affects between 30 to 65% of the population with a higher prevalence for young women. The patients with DTM report a decrease of their personal, social and professional quality of life. Treatment usually relies on physical therapy. Among the different technics that can be used in physical therapy, there is growing evidence advocating the efficacy of using motor imagery (i.e. imagining a movement with no concomitant physical execution) during rehabilitation. It has also been shown that the benefits of practicing motor imagery depend on the ability (i.e., the higher the ability, the greater the benefits). However, there is no investigation of the motor imagery ability of the tongue and mouth movements conditioning the use of motor imagery during TMD rehabilitation. The objective of the study is to investigate the ability of imagining tongue and mouth movements using the Tongue and Mouth Imagery Questionnaire (TMIQ) as compare to the gold-standard Kinesthetic and Visual Imagery Questionnaire (KVIQ - Malouin et al., 2007).

Detailed description: Principal objective:

Assess the validity construct of the Tongue and Mouth Imagery Questionnaire (TMIQ) as compare to the gold-standard Kinesthetic and Visual Imagery Questionnaire (KVIQ - Malouin et al., 2007), both measuring the motor imagery vividness.

Secondary objectives:

1. Assess the reliability of the TMIQ using a test-retest.
2. Assess the temporal coupling (i.e., the ratio between imagined and physically practiced movement) and compare these ratios for the TMIQ and KVIQ.
3. Investigate the effect of TMD by comparing the vividness scores of TMIQ for respectively subject with and with no TMD.
4. Investigate the effect of TMD by comparing the vividness scores of KVIQ for respectively subject with and with no TMD.
5. Investigate the effect of TMD by comparing the temporal coupling scores of TMIQ for respectively subject with and with no TMD.
6. Investigate the effect of TMD by comparing the temporal coupling scores of KVIQ for respectively subject with and with no TMD.

Eligibility criteria: Inclusion Criteria:

* age between 18 and 75 years
* A voluntary individual who has given informed consent after receiving clear, fair and appropriate information about the study.

For DTM group participants

* inclusion during the DTM rehabilitation in the physical therapy firm "Cabinet Saint Alexandre".
* beneficiary of the social security scheme

Exclusion Criteria:

* The presence of a short tongue brake (Marchesan, 2005)
* Lingual immaturity evaluated by the Tardieu test (Jouannaud et al. 1972)
* Patients who had orthognathic surgery within 6 months post- operative, or facial fractures according to the same deadlines
* The presence of peripheral facial palsy
* Current participation in another research whose objective would be the evaluation of a therapeutic, drug or not, introducing an experimental bias.

Primary outcomes:
measure: vividness score of imagined movements of the TMIQ for the DTM group
timeFrame: at study inclusion, i.e day 1
measure: vividness score of imagined movements of the TMIQ for the CTL group
timeFrame: at study inclusion, i.e day 1
measure: vividness score of imagined movements of the KVIQ for the DTM group
timeFrame: at study inclusion, i.e day 1
measure: vividness score of imagined movements of the KVIQ for the CTL group
timeFrame: at study inclusion, i.e day 1
Secondary outcomes:
measure: vividness score of imagined movements of the TMIQ for the DTM group
timeFrame: at study completion, between 8 days to 45 days after inclusion
measure: vividness score of imagined movements of the TMIQ for the CTL group
timeFrame: at study completion, between 8 days to 45 days after inclusion
measure: Temporal coupling to imagined movements of the TMIQ for the DTM group
timeFrame: at study completion, between 8 days to 45 days after inclusion
measure: Temporal coupling to imagined movements of the TMIQ for the CTL group
timeFrame: at study inclusion, i.e day 1
measure: Temporal coupling to imagined movements of the TMIQ for the CTL group
timeFrame: at study completion, between 8 days to 45 days after inclusion
Other outcomes:
measure: mental representation of the maximal opening of the mouth for the DTM group
timeFrame: at study inclusion, i.e day 1
measure: mental representation of the maximal opening of the mouth for the CTL group
timeFrame: at study inclusion, i.e day 1
measure: Accuracy of tongue pointing against the wood examination stick for the DTM group
timeFrame: at study inclusion, i.e day 1
measure: Accuracy of tongue pointing against the wood examination stick for the CTL group
timeFrame: at study inclusion, i.e day 1
Locations:
city: Lyon
country: France
facility: Cabinet Saint Alexandre
Study officials:
affiliation: Cabinet de kinésithérapie Saint Alexandre
name: Caroline Alvarado-Faysse, PT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Alvarado C, Arminjon A, Damieux-Verdeaux C, Lhotte C, Condemine C, Cousin AS, Sigaux N, Bouletreau P, Mateo S. Impaired tongue motor control after temporomandibular disorder: A proof-of-concept case-control study of tongue print. Clin Exp Dent Res. 2022 Apr;8(2):529-536. doi: 10.1002/cre2.549. Epub 2022 Feb 27.