Clinical trial NCT04481165: Experience of Adolescents With Anorexia Nervosa Towards Antidepressants
Official title: Subjective Experience of Adolescents Suffering From Anorexia Nervosa With Antidepressants
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Adolescents Cared for Anorexia Nervosa at Maison de Solenn
Keywords: Anorexia nervosa
Adolescents
Antidepressive agents
Lead sponsor: Assistance Publique - Hôpitaux de Paris
Sponsor class: OTHER
First posted: 2020-07-22
Enrollment: 15
Sex: ALL
Minimum age (years): 12
Maximum age (years): 25
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adolescents (between 12 and 25 years) suffer from anorexia nervosa, at the Maison de Solenn, Cochin Hospital, Paris, France

Brief summary: The purpose of this study is to explore the experience of adolescents suffering from anorexia nervosa confronted with the prescription of antidepressants

Detailed description: In our adolescent psychiatric unit, antidepressant's prescription is common during the care pathway for adolescents with anorexia nervosa.

The literature highlights a paradox between scientific data and clinical practice, based on expert consensus. There are a very few qualitative studies in this subject and none of them concern adolescents.

The purpose of this qualitative study is to explore the experience and opinion of adolescents suffering from anorexia nervosa confronted with the prescription of antidepressants

Eligibility criteria: Inclusion Criteria:

* Adolescents aged 12 to 25
* Suffering from anorexia nervosa \[according to DSM-5 criteria\]
* Has been prescribed for a type of SSRIs antidepressant (still ongoing or interrupted at the time of the interview)
* Non-opposition to the study

Exclusion Criteria:

* Atypical eating disorder that do not meet DSM-5 criteria for restrictive anorexia nervosa
* Body Mass Index \< 15
* Prescribed for another antidepressant than SSRIs

Primary outcomes:
measure: Qualitative data / Experience of taking anidepressants
timeFrame: At the time of inclusion (Day 0)
Secondary outcomes:
Other outcomes:
Locations:
city: Paris
country: France
facility: Maison de Solenn / Cochin Hospital
Study officials:
affiliation: APHP, Hôpital Cochin, Maison de Solenn, F-75014 Paris, France
name: Maude LUDOT, Psychiatrist
role: PRINCIPAL_INVESTIGATOR
affiliation: APHP, Hôpital Cochin, Maison de Solenn, F-75014 Paris, France
name: Marie-Rose MORO, PU-PH
role: STUDY_CHAIR
affiliation: APHP, Hôpital Cochin, Maison de Solenn, F-75014 Paris, France
name: Corinne BLANCHET, PH
role: STUDY_DIRECTOR
affiliation: APHP, Hôpital Cochin, Maison de Solenn, F-75014 Paris, France
name: Jonathan LACHAL, PHU
role: STUDY_DIRECTOR
References:
citation: Leble N, Radon L, Rabot M, Godart N. [Depressive symptoms during anorexia nervosa: State of the art and consequences for an appropriate use of antidepressants]. Encephale. 2017 Feb;43(1):62-68. doi: 10.1016/j.encep.2016.02.017. Epub 2016 Jul 21. French.
citation: Anderson C, Roy T. Patient experiences of taking antidepressants for depression: a secondary qualitative analysis. Res Social Adm Pharm. 2013 Nov-Dec;9(6):884-902. doi: 10.1016/j.sapharm.2012.11.002. Epub 2012 Dec 4.