Clinical trial NCT04036435: Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
Official title: An Open-Label, Multi-Center Extension Study to Characterize the Long-Term Safety and Efficacy of BMS-986165 in Subjects With Moderate-to-Severe Plaque Psoriasis
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: PHASE3
Conditions: Psoriasis
Keywords: Psoriasis
Lead sponsor: Bristol-Myers Squibb
Sponsor class: INDUSTRY
First posted: 2019-07-29
Enrollment: 1452
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The main purpose of this study is to characterize the long-term safety and efficacy of the drug Deucravacitinib (BMS-986165) in patients who have been previously enrolled in an applicable Phase 3 psoriasis study.


Eligibility criteria: Inclusion Criteria:

* Completion of the protocol-required treatment period in an applicable study of BMS-986165 in moderate-to-severe psoriasis
* Women must not be pregnant, lactating, or breastfeeding

Exclusion Criteria:

* Any disease or medical condition that the investigator feels that would make the patient unsuitable for this study.
* To be eligible for the study, a participant must not have active signs or symptoms of tuberculosis (TB) as judged by the investigator.

Other protocol-defined inclusion/exclusion criteria apply

Primary outcomes:
measure: Incidence of Adverse Events (AEs)
timeFrame: Up to 244 weeks
measure: Incidence of Serious Adverse Events (SAEs)
timeFrame: Up to 244 weeks
Secondary outcomes:
measure: static Physician Global Assessment (sPGA) 0/1 response
timeFrame: Up to 240 weeks
measure: Psoriasis Area and Severity Index (PASI) 75 response
timeFrame: Up to 240 weeks
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: Total Skin and Beauty Dermatology Center
state: Alabama
city: Birmingham
country: United States
facility: Local Institution - 0278
state: Alabama
city: Phoenix
country: United States
facility: Alliance Dermatology and Mohs Center - Phoenix
state: Arizona
city: Phoenix
country: United States
facility: Arizona Research Center
state: Arizona
city: Tucson
country: United States
facility: Synexus - Orange Grove Family Practice
state: Arizona
city: Fort Smith
country: United States
facility: Johnson Dermatology
state: Arkansas
city: Hot Springs
country: United States
facility: Burke Pharmaceutical Research
state: Arkansas
city: Rogers
country: United States
facility: Northwest Arkansas Clinical Trials Center, PLLC
state: Arkansas
city: Fountain Valley
country: United States
facility: First OC Dermatology & Belle-Aimee Skincare Clinic Fountain Valley
state: California
city: Fresno
country: United States
facility: Local Institution - 0206
state: California
city: Irvine
country: United States
facility: Local Institution - 0017
state: California
city: Long Beach
country: United States
facility: Interspond - Long Beach Clinical Trials
state: California
city: Los Angeles
country: United States
facility: Dermatology Research Associates - Los Angeles
state: California
city: Los Angeles
country: United States
facility: Local Institution - 0236
state: California
city: San Diego
country: United States
facility: University of California San Diego Health Systems
state: California
city: San Diego
country: United States
facility: Therapeutics Clinical Research
state: California
city: San Diego
country: United States
facility: University Dermatology Group
state: California
city: San Luis Obispo
country: United States
facility: Local Institution - 0094
state: California
city: Santa Monica
country: United States
facility: Clinical Science Institute
state: California
city: Santa Rosa
country: United States
facility: NorthBay Clinical Research
state: California
city: Santa Rosa
country: United States
facility: Synexus - Santa Rosa
state: California
city: Sherman Oaks
country: United States
facility: Local Institution - 0042
state: California
city: Walnut Creek
country: United States
facility: Care Access Research - Walnut Creek
state: California
city: Bridgeport
country: United States
facility: New England Research Associates
state: Connecticut
city: Stamford
country: United States
facility: Stamford Therapeutics Consortium
state: Connecticut
city: Boca Raton
country: United States
facility: Local Institution - 0170
state: Florida
city: DeLand
country: United States
facility: ERN - Accel Research Sites
state: Florida
city: Hialeah
country: United States
facility: Indago Research and Health Center
state: Florida
city: Miami Lakes
country: United States
facility: Interspond - Savin Medical Group
state: Florida
city: Miami Lakes
country: United States
facility: Local Institution - 0007
state: Florida
city: Miami
country: United States
facility: LCC Medical Research
state: Florida
city: Miami
country: United States
facility: International Dermatology Research
state: Florida
city: Miami
country: United States
facility: Well Pharma Medical Research
state: Florida
city: Miami
country: United States
facility: Local Institution - 0216
state: Florida
city: Port Orange
country: United States
facility: Local Institution - 0198
state: Florida
city: Tampa
country: United States
facility: Local Institution - 0233
state: Florida
city: Tampa
country: United States
facility: Local Institution - 0008
state: Florida
city: Marietta
country: United States
facility: Local Institution - 0013
state: Georgia
city: Sandy Springs
country: United States
facility: Local Institution - 0235
state: Georgia
city: Meridian
country: United States
facility: Treasure Valley Dermatology & Skin Cancer Center
state: Idaho
city: Springfield
country: United States
facility: Springfield Clinic
state: Illinois
city: West Dundee
country: United States
facility: Dundee Dermatology
state: Illinois
city: Evansville
country: United States
facility: Deaconess Clinic Downtown
state: Indiana
city: Evansville
country: United States
facility: Clinical Research Advantage - Evansville - South Kenmore Drive
state: Indiana
city: Indianapolis
country: United States
facility: Dawes Fretzin Dermatology Group
state: Indiana
city: Plainfield
country: United States
facility: Local Institution - 0020
state: Indiana
city: South Bend
country: United States
facility: The South Bend Clinic
state: Indiana
city: Louisville
country: United States
facility: Local Institution - 0040
state: Kentucky
city: Lake Charles
country: United States
facility: Shondra L. Smith, M.D.
state: Louisiana
city: Monroe
country: United States
facility: Clinical Trials of America - Monroe
state: Louisiana
city: Boston
country: United States
facility: Tufts Medical Center
state: Massachusetts
city: Boston
country: United States
facility: Local Institution - 0291
state: Massachusetts
city: Chestnut Hill
country: United States
facility: Ora
state: Massachusetts
city: Methuen
country: United States
facility: Local Institution - 0234
state: Massachusetts
city: Quincy
country: United States
facility: DermCare Experts
state: Massachusetts
city: Ann Arbor
country: United States
facility: David Fivenson MD Dermatology
state: Michigan
city: Fort Gratiot
country: United States
facility: Hamzavi Dermatology
state: Michigan
city: Troy
country: United States
facility: Local Institution - 0025
state: Michigan
city: New Brighton
country: United States
facility: Associated Skin Care Specialists - Minnesota Clinical Study Center
state: Minnesota
city: Saint Louis
country: United States
facility: Washington University School of Medicine - West County Dermatology
state: Missouri
city: Las Vegas
country: United States
facility: Clinical Research Consortium - Las Vegas
state: Nevada
city: Berlin
country: United States
facility: Hassman Research Institute
state: New Jersey
city: East Windsor
country: United States
facility: Local Institution - 0016
state: New Jersey
city: Bronx
country: United States
facility: Montefiore Medical Center - Bronx
state: New York
city: Kew Gardens
country: United States
facility: Forest Hills Dermatology Group
state: New York
city: New York
country: United States
facility: Local Institution - 0058
state: New York
city: Stony Brook
country: United States
facility: Local Institution - 0218
state: New York
city: Cary
country: United States
facility: PMG Research of Cary
state: North Carolina
city: Wilmington
country: United States
facility: Wilmington Dermatology Center
state: North Carolina
city: Columbus
country: United States
facility: Radiant Research - Columbus
state: Ohio
city: Columbus
country: United States
facility: ClinOhio Research Services
state: Ohio
city: Fairborn
country: United States
facility: Local Institution - 0176
state: Ohio
city: Norman
country: United States
facility: Central Sooner Research
state: Oklahoma
city: Oklahoma City
country: United States
facility: Unity Clinical Research
state: Oklahoma
city: Portland
country: United States
facility: Local Institution - 0009
state: Oregon
city: Portland
country: United States
facility: Local Institution - 0167
state: Oregon
city: Exton
country: United States
facility: Local Institution - 0045
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Local Institution - 0282
state: Pennsylvania
city: Anderson
country: United States
facility: Radiant Research - Anderson
state: South Carolina
city: Charleston
country: United States
facility: Clinical Research Center of the Carolinas
state: South Carolina
city: Greer
country: United States
facility: Local Institution - 0037
state: South Carolina
city: North Charleston
country: United States
facility: Coastal Carolina Research Center - Mount Pleasant
state: South Carolina
city: Rapid City
country: United States
facility: Local Institution - 0004
state: South Dakota
city: Goodlettsville
country: United States
facility: Rivergate Dermatology - Main Office
state: Tennessee
city: Jackson
country: United States
facility: Clinical Research Solutions - Jackson
state: Tennessee
city: Knoxville
country: United States
facility: Dermatology Associates of Knoxville
state: Tennessee
city: Knoxville
country: United States
facility: The Skin Wellness Center
state: Tennessee
city: Arlington
country: United States
facility: Local Institution - 0006
state: Texas
city: Bellaire
country: United States
facility: Bellaire Dermatology
state: Texas
city: Dallas
country: United States
facility: Local Institution - 0015
state: Texas
city: Dallas
country: United States
facility: Local Institution - 0195
state: Texas
city: Dallas
country: United States
facility: Local Institution - 0030
state: Texas
city: Dallas
country: United States
facility: Menter Dermatology Research Institute
state: Texas
city: Houston
country: United States
facility: Center for Clinical Studies - Texas Medical Center
state: Texas
city: Pflugerville
country: United States
facility: Austin Institute for Clinical Research - Pflugerville
state: Texas
city: San Antonio
country: United States
facility: University of Texas Health Science Center at San Antonio
state: Texas
city: San Antonio
country: United States
facility: Dermatology Clinical Research Center of San Antonio
state: Texas
city: Sugar Land
country: United States
facility: Interspond - Acclaim Dermatology
state: Texas
city: Sugar Land
country: United States
facility: Interspond - Houston Center for Clinical Research
state: Texas
city: Webster
country: United States
facility: Center for Clinical Studies - Webster
state: Texas
city: Seattle
country: United States
facility: Local Institution - 0265
state: Washington
city: Phillip
country: Australia
facility: Woden Dermatology
state: Australian Capital Territory
city: Darlinghurst
country: Australia
facility: Holdsworth House Medical Practice
state: New South Wales
city: Kogarah
country: Australia
facility: St. George Dermatology & Skin Care Centre
state: New South Wales
city: Westmead
country: Australia
facility: Local Institution - 0250
state: New South Wales
city: Benowa
country: Australia
facility: The Skin Centre
state: Queensland
city: Woolloongabba
country: Australia
facility: Veracity Clinical Research
state: Queensland
city: Hectorville
country: Australia
facility: North Eastern Health Specialists
state: South Australia
city: Box Hill
country: Australia
facility: Local Institution - 0245
state: Victoria
city: Carlton
country: Australia
facility: Skin and Cancer Foundation
state: Victoria
city: East Melbourne
country: Australia
facility: Sinclair Dermatology
state: Victoria
city: Parkville
country: Australia
facility: Local Institution - 0251
state: Victoria
city: Perth
country: Australia
facility: Local Institution - 0247
state: Western Australia
city: Calgary
country: Canada
facility: Beacon Dermatology
state: Alberta
city: Edmonton
country: Canada
facility: Stratica Medical
state: Alberta
city: Surrey
country: Canada
facility: SkinFit MD Laser and Cosmetic Clinic
state: British Columbia
city: Vancouver
country: Canada
facility: University of British Columbia
state: British Columbia
city: Winnipeg
country: Canada
facility: Wiseman Dermatology Research
state: Manitoba
city: Ajax
country: Canada
facility: CCA Medical Research
state: Ontario
city: London
country: Canada
facility: Mediprobe Research
state: Ontario
city: London
country: Canada
facility: Local Institution - 0090
state: Ontario
city: Markham
country: Canada
facility: Lynderm Research
state: Ontario
city: Mississauga
country: Canada
facility: DermEdge
state: Ontario
city: North Bay
country: Canada
facility: North Bay Dermatology Centre
state: Ontario
city: North York
country: Canada
facility: Office of Dr. Niakosari Firouzeh
state: Ontario
city: Oakville
country: Canada
facility: Institute of Cosmetic and Laser Surgery
state: Ontario
city: Peterborough
country: Canada
facility: Local Institution - 0088
state: Ontario
city: Richmond Hill
country: Canada
facility: Local Institution - 0082
state: Ontario
city: Toronto
country: Canada
facility: Toronto Dermatology Centre
state: Ontario
city: Toronto
country: Canada
facility: Local Institution - 0132
state: Ontario
city: Waterloo
country: Canada
facility: Kim Papp Clinical Research
state: Ontario
city: Windsor
country: Canada
facility: XLR8 Medical Research
state: Ontario
city: Montreal
country: Canada
facility: Docteur David Gratton Dermatologue
state: Quebec
city: Montreal
country: Canada
facility: Siena Medical Research
state: Quebec
city: Quebec
country: Canada
facility: Local Institution - 0258
city: Beijing
country: China
facility: Local Institution
state: Beijing
city: Beijing
country: China
facility: Local Institution
state: Beijing
city: Chongqing
country: China
facility: Local Institution
state: Chongqing
city: Wuhan
country: China
facility: Local Institution
state: Hubei
city: Wuhan
country: China
facility: Local Institution
state: Hubei
city: Nanjing
country: China
facility: Local Institution - 0312
state: Jiangsu
city: Changchun
country: China
facility: Local Institution
state: Jilin
city: Dalian
country: China
facility: Local Institution
state: Liaoning
city: Taiyuan
country: China
facility: Local Institution
state: Shan1xi
city: Shanghai
country: China
facility: Local Institution - 0292
state: Shanghai
city: Chengdu
country: China
facility: Local Institution
state: Sichuan
city: Hangzhou
country: China
facility: Local Institution
state: Zhejiang
city: Hangzhou
country: China
facility: Local Institution
state: Zhejiang
city: Hangzhou
country: China
facility: Local Institution
state: Zhejiang
city: Hangzhou
country: China
facility: Local Institution
state: Zhejiang
city: Jihlava 1
country: Czechia
facility: Nemocnice Jihlava
city: Novy Jicin
country: Czechia
facility: Nemocnice Novy Jicin a.s.
city: Olomouc
country: Czechia
facility: MUDr. Helena Korandova
city: Ostrava
country: Czechia
facility: Fakultni Nemocnice Ostrava
city: Praha 10
country: Czechia
facility: Clintrial
city: Praha 1
country: Czechia
facility: Sanatorium profesora Arenbergera
city: Usti nad Labem
country: Czechia
facility: Krajska zdravotni - Masarykova nemocnice v Usti nad Labem
city: Tampere
country: Finland
facility: Local Institution - 0279
city: Nice cedex 3
country: France
facility: Centre Hospitalier Universitaire de Nice Hopital lArchet
city: Augsburg
country: Germany
facility: Licca Clinical Research Institute
city: Bochum
country: Germany
facility: Hautarztpraxis Dr. Niesmann & Dr. Othlinghaus
city: Dresden
country: Germany
facility: Hautarztpraxis Dr. Beatrice Gerlach
city: Frankfurt am Main
country: Germany
facility: Synexus Frankfurt Clinical Research
city: Hamburg
country: Germany
facility: Local Institution - 0263
city: Kiel
country: Germany
facility: Dermakiel - Allergie Und Haut Centrum
city: Langenau
country: Germany
facility: Praxis Dr. Beate Schwarz
city: Straubing
country: Germany
facility: Praxis Dr. med. Wilfried Steinborn
city: Wuppertal
country: Germany
facility: CentroDerm Privatklinik
city: Budapest
country: Hungary
facility: Qualiclinic Egeszsegugyi Szolgaltato es Kutatasszervezo Kft.
city: Budapest
country: Hungary
facility: Synexus Magyarorszag
city: Budapest
country: Hungary
facility: Semmelweis Egyetem
city: Debrecen
country: Hungary
facility: Synexus Magyarorszag Egeszsegugyi Szolgaltato - Debrecen Affiliated Site
city: Debrecen
country: Hungary
facility: Debreceni Egyetem Klinikai Kozpont
city: Gyula
country: Hungary
facility: Synexus Magyarorszag Egeszsegugyi Szolgaltato - Gyula
city: Nyiregyhaza
country: Hungary
facility: Josa Andras Oktatokorhaza - Szabolcs Szatmar-Bereg Megyei Onkormanyzat
city: Pecs
country: Hungary
facility: Pecsi Tudomanyegyetem Klinikai Kozpont
city: Szolnok
country: Hungary
facility: Allergo-Derm Bakos
city: Zalaegerszeg
country: Hungary
facility: Synexus Magyarorszag Egeszsegugyi Szolgaltato - Zalaegerszeg
city: Haifa
country: Israel
facility: Local Institution - 0237
city: Petah Tikva
country: Israel
facility: Local Institution
city: Ramat Gan
country: Israel
facility: Local Institution
city: Nagoya
country: Japan
facility: Local Institution - 0065
state: Aichi
city: Fukuoka-shi
country: Japan
facility: Fukuoka University Hospital
state: Fukuoka
city: Sapporo
country: Japan
facility: Sapporo Skin Clinic
state: Hokkaido
city: Kobe
country: Japan
facility: Kobe University Hospital
state: Hyogo
city: Isehara City
country: Japan
facility: Tokai University Hospital
state: Kanagawa
city: Yokohama-Shi
country: Japan
facility: Local Institution - 0075
state: Kanagawa
city: Yokohama
country: Japan
facility: Yokohama City University Hospital
state: Kanagawa
city: Nankoku
country: Japan
facility: Local Institution - 0076
state: Kochi
city: Kyoto-city
country: Japan
facility: Local Institution - 0066
state: Kyoto
city: Kyoto-City
country: Japan
facility: Kyoto University Hospital
state: Kyoto
city: Tsu
country: Japan
facility: Mie University Hospital
state: MIE
city: Matsumoto
country: Japan
facility: Local Institution - 0072
state: Nagano
city: Kurashiki
country: Japan
facility: Kurashiki Central Hospital
state: Okayama
city: Hamamatsu
country: Japan
facility: Hamamatsu University Hospital
state: Shizuoka
city: Shimotsuke
country: Japan
facility: Jichi Medical University Hospital
state: Tochigi
city: Itabashi-Ku
country: Japan
facility: Teikyo University Hospital
state: Tokyo
city: Itabashi-ku
country: Japan
facility: Nihon University Itabashi Hospital
state: Tokyo
city: Minato-ku
country: Japan
facility: The Jikei University Hospital
state: Tokyo
city: Shinagawa
country: Japan
facility: Local Institution - 0062
state: Tokyo
city: Shinjuku-ku
country: Japan
facility: Tokyo Medical University Hospital
state: Tokyo
city: Shinjuku-ku
country: Japan
facility: Japan Community Health Care Organization Tokyo Yamate Medical Center
state: Tokyo
city: Kumamoto
country: Japan
facility: Kumamoto University Hospital
city: Osaka
country: Japan
facility: Local Institution - 0073
city: Osaka
country: Japan
facility: Local Institution - 0067
city: Bucheon-si
country: Korea, Republic of
facility: Local Institution
city: Busan
country: Korea, Republic of
facility: Local Institution - 0054
city: Goyang-si
country: Korea, Republic of
facility: Local Institution
city: Gwangju
country: Korea, Republic of
facility: Local Institution - 0310
city: Hwaseong-si
country: Korea, Republic of
facility: Local Institution
city: Incheon
country: Korea, Republic of
facility: Local Institution
city: Incheon
country: Korea, Republic of
facility: Local Institution
city: Seongnam-si
country: Korea, Republic of
facility: Local Institution
city: Seongnam-si
country: Korea, Republic of
facility: Local Institution - 0051
city: Seoul
country: Korea, Republic of
facility: Local Institution
city: Seoul
country: Korea, Republic of
facility: Local Institution - 0305
city: Seoul
country: Korea, Republic of
facility: Local Institution - 0055
city: Seoul
country: Korea, Republic of
facility: Local Institution
city: Seoul
country: Korea, Republic of
facility: Local Institution
city: Seoul
country: Korea, Republic of
facility: Local Institution - 0053
city: Seoul
country: Korea, Republic of
facility: Local Institution
city: Suwon
country: Korea, Republic of
facility: Local Institution
city: Mount Cook
country: New Zealand
facility: Local Institution
city: Tauranga
country: New Zealand
facility: Local Institution
city: Warszawa
country: Poland
facility: Local Institution - 0138
state: MZ
city: Bialystok
country: Poland
facility: Local Institution - 0104
city: Bialystok
country: Poland
facility: ZDROWIE OSTEO-MEDIC s.c. Lidia i Artur Racewicz, Agnieszka i Jerzy Supronik
city: Bialystok
country: Poland
facility: ClinicMed Daniluk Nowak Spolka Jawna
city: Elblag
country: Poland
facility: Centrum Kliniczno Badawcze J Brzezicki B Gornikiewicz Brzezicka Lekarze Spolka Partnerska
city: Gdansk
country: Poland
facility: Local Institution - 0149
city: Gdynia
country: Poland
facility: Synexus Polska Oddzial w Gdyni
city: Iwonicz-Zdroj
country: Poland
facility: Zespol Naukowo-Leczniczy Iwolang
city: Katowice
country: Poland
facility: Synexus - Katowice
city: Krakow
country: Poland
facility: Krakowskie Centrum Medyczne
city: Krak
country: Poland
facility: Pratia MCM Krakow
city: Lodz
country: Poland
facility: Centrum Terapii Wspolczesnej
city: Lodz
country: Poland
facility: Local Institution - 0114
city: Lodz
country: Poland
facility: Local Institution - 0144
city: Lodz
country: Poland
facility: Centrum Medyczne All-Med
city: Lublin
country: Poland
facility: Niepubliczny Zaklad Opieki Zdrowotnej MED-LASER
city: Olsztyn
country: Poland
facility: Miejski Szpital Zespolony w Olsztynie
city: Osielsko
country: Poland
facility: DermoDent - Centrum Medyczne Czajkowscy
city: Poznan
country: Poland
facility: Solumed Centrum Medyczne
city: Poznan
country: Poland
facility: Local Institution - 0103
city: Siedlce
country: Poland
facility: ETG - Siedlce
city: Skierniewice
country: Poland
facility: ETG - Skierniewice
city: Torun
country: Poland
facility: Local Institution - 0125
city: Warsaw
country: Poland
facility: Local Institution - 0111
city: Warszawa
country: Poland
facility: Clinical Research Group
city: Warszawa
country: Poland
facility: High-Med Przychodnia Specjalistyczna
city: Warszawa
country: Poland
facility: ETG - Warszawa
city: Wroc?aw
country: Poland
facility: Local Institution - 0137
city: Wroclaw
country: Poland
facility: dermMedica Sp. z o.o.
city: Wroclaw
country: Poland
facility: Local Institution - 0124
city: Wroclaw
country: Poland
facility: Centrum Medyczne Oporow
city: San Juan
country: Puerto Rico
facility: Local Institution - 0289
city: Ekaterinburg
country: Russian Federation
facility: Local Institution - 0178
city: Kazan
country: Russian Federation
facility: Local Institution - 0172
city: Krasnodar
country: Russian Federation
facility: Local Institution - 0187
city: Moscow
country: Russian Federation
facility: Local Institution - 0171
city: Moscow
country: Russian Federation
facility: Local Institution - 0175
city: Moscow
country: Russian Federation
facility: Local Institution - 0169
city: Ryazan
country: Russian Federation
facility: Local Institution - 0190
city: Saint Petersburg
country: Russian Federation
facility: Local Institution - 0179
city: Saint Petersburg
country: Russian Federation
facility: Local Institution - 0182
city: Saint Petersburg
country: Russian Federation
facility: Local Institution - 0201
city: Saratov
country: Russian Federation
facility: Local Institution - 0202
city: Smolensk
country: Russian Federation
facility: Local Institution - 0184
city: Yaroslavl
country: Russian Federation
facility: Local Institution - 0222
city: Alcorcon
country: Spain
facility: Local Institution - 0223
city: Badalona
country: Spain
facility: Hospital Universitari Germans Trias i Pujol
city: Barakaldo
country: Spain
facility: Hospital Universitario Cruces
city: Cordoba
country: Spain
facility: Local Institution - 0225
city: Las Palmas De Gran Canaria
country: Spain
facility: Local Institution - 0226
city: Madrid
country: Spain
facility: Hospital Universitario Ramon Y Cajal
city: Malaga
country: Spain
facility: Local Institution - 0227
city: Manises
country: Spain
facility: Hospital de Manises
city: Pozuelo de Alarcon
country: Spain
facility: Hospital Universitario Quironsalud Madrid
city: Boras
country: Sweden
facility: Ladulaas Kliniska Studier
city: Lund
country: Sweden
facility: ProbarE i Lund
city: Solna
country: Sweden
facility: Local Institution - 0186
city: Kaohsiung
country: Taiwan
facility: Local Institution - 0079
city: Kaohsiung
country: Taiwan
facility: Local Institution - 0297
city: Taipei City
country: Taiwan
facility: Local Institution
city: Taipei
country: Taiwan
facility: Local Institution
city: Taipei
country: Taiwan
facility: Local Institution - 0153
city: Taipei
country: Taiwan
facility: Local Institution
city: Taipei
country: Taiwan
facility: Local Institution
city: Cannock
country: United Kingdom
facility: MAC Clinical Research - Cannock
city: Chorley
country: United Kingdom
facility: Synexus - Lancashire Clinical Research Centre
city: Chorley
country: United Kingdom
facility: Synexus - Manchester Clinical Research Centre
city: Chorley
country: United Kingdom
facility: Synexus - Merseyside Clinical Research Centre
city: Cornwall
country: United Kingdom
facility: Mounts Bay Medical
city: Dudley
country: United Kingdom
facility: The Dudley Group NHS Foundation Trust
city: Durham
country: United Kingdom
facility: MAC Clinical Research - Stockton
city: Lancashire
country: United Kingdom
facility: MAC Clinical Research - Blackpool
city: Leicestershire
country: United Kingdom
facility: Burbage Surgery
city: London
country: United Kingdom
facility: Guys and Saint Thomas NHS Foundation Trust
city: Manchester
country: United Kingdom
facility: MAC Clinical Research - Manchester
city: Manchester
country: United Kingdom
facility: Salford Royal NHS Foundation Trust
city: Prescot
country: United Kingdom
facility: MAC Clinical Research - Liverpool
Study officials:
affiliation: Bristol-Myers Squibb
name: Bristol-Myers Squibb
role: STUDY_DIRECTOR
References: