Clinical trial NCT03902236: Reaction Time and Postural Control in Individuals With Cystic Fibrosis and Bronchiectasis
Official title: Evaluation of Reaction Time and Postural Control in Individuals With Cystic Fibrosis and Bronchiectasis
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Cystic Fibrosis
Bronchiectasis
Keywords: postural control
reaction time
cystic fibrosis
Bronchiectasis
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2019-04-03
Enrollment: 60
Sex: ALL
Minimum age (years): 6
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Children diagnosed with cystic fibrosis and bronchiectasis is referred from Hacettepe University, Pediatric Chest Diseases Department to Hacettepe University Department of Physiotheraphy and Rehabilitation will be included in this study. And also, healthy children at 6-18 years olds who are relatives of patients admitted to the our department will be included in this study.

Brief summary: The aim of this study is to evaluate the reaction time and postural control and to investigate the relationship between reaction time, exercise capacity, muscle oxygenation and balance in children with cystic fibrosis (CF) and non-CF bronchiectasis. 40 patients including 20 CF patients and 20 non-CF bronchiectasis and 20 healthy individuals will be included in this study. Demographic and physical characteristics' will be recorded. Lung function testing will be performed. Balance will be assessed using functional reach test, exercise capacity was measured using the incremental shuttle walking test and reaction time will be assessed using ''Fitlight TrainerTM''. Heart rate, respiratory rate, oxygen saturation, muscle oxygenation, dyspnea and fatigue perception will be measured before and after exercise test and reaction time measurement.


Eligibility criteria: Inclusion Criteria:

* Children diagnosed with bronchiectasis and cystic fibrosis at 6-18 years old age for the bronchiectasis and cystic fibrosis groups respectively
* Healthy children at 6-18 years old age for the healthy group.
* Stable medical condition (free from the acute exacerbation)
* Children who have not participated in the planned exercise training program in the last 3 months
* Compliance with the tests

Exclusion Criteria:

* Children who have a physical problems that limit the application of the tests
* Acute infection or unstable medical status

Primary outcomes:
measure: Reaction Time and Postural Control
timeFrame: 8 minutes
measure: Muscle oxygenation
timeFrame: 40 minutes (during the incremental shuttle walk test+reaction and postural control protocol)
measure: Exercise capacity
timeFrame: 20 minutes
measure: Balance
timeFrame: 5 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
Study officials:
References:
citation: Borges NR, Driller MW. Wearable Lactate Threshold Predicting Device is Valid and Reliable in Runners. J Strength Cond Res. 2016 Aug;30(8):2212-8. doi: 10.1519/JSC.0000000000001307.
citation: Klein M, Gauggel S, Sachs G, Pohl W. Impact of chronic obstructive pulmonary disease (COPD) on attention functions. Respir Med. 2010 Jan;104(1):52-60. doi: 10.1016/j.rmed.2009.08.008. Epub 2009 Sep 11.