Clinical trial NCT05707000: Comparison of Quadriceps Strengthening and Kinesiotaping on Gait in Knee Osteoarthritis
Official title: Comparison of Concentric Quadriceps Strengthening and Facilitatory Kinesiotaping on Gait Parameters in Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Knee osteoarthritis
Quadriceps
Kinesiotaping
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-01-31
Enrollment: 38
Sex: ALL
Minimum age (years): 50
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this research is to determine the Effects of facilitatory Kinesio-taping and concentric quadriceps strengthening on gait parameters in knee osteoarthritis. Randomized clinical trials will be done at Physio Experts Clinic, Islamabad. The sample size is 38. The subjects were divided in two groups, with 19 subjects in Group A and 19 in Group B. Study duration was of 6 months. Sampling technique applied was Non probability Convenience Sampling technique. Both males and females of aged 50-60 years with Knee OA grade 2 or 3 were included. Tools used in the study are Numeric Pain Rating Score (NPRS), dynamometer, WOMAC questionnaire and Mobile app for measuring Temporospatial gait parameters.

Detailed description: Osteoarthritis is one of the most common musculoskeletal disorders in adults. It is a degenerative joint disease affecting 15%-40% of people more than 40 years of age. The term osteoarthritis was authored in 1886 by the English doctor, John Kent Spender. Clinical assessment to recognize OA from RA and other comparable conditions turned out to be broadly acknowledged by the main decade of the twentieth century enormous because of the endeavors set forward by Archibald E.

Osteoarthritis is a degenerative joint condition that causes other joint tissues to lose gross cartilage and to experience morphological damage. Pathological changes seen in knee osteoarthritis joints include progressive loss and destruction of articular cartilage, thickening of the subchondral bone, formation of osteophytes, variable degrees of inflammation of the synovium, degeneration of ligaments and menisci of the knee and hypertrophy of the joint capsule. Biomechanical factor that is assumed to contribute to the etiology of OA is laxity of knee joint, which is described as the rotation or displacement of femur from tibia. One research found that Varus-valgus laxity in patients with unaltered knees and unilateral OA is wider than in stable healthy participants, indicating knee joint laxity may be disease predisposing. the progress of the lateral and medial knee OA, as defined by narrowing of joint space and a degradation of physical activity, was found to have been linked with lower limb valgus-Varus alignment.

The main focus in OA management is on promoting self-management, reducing pain, optimize function, and modifying the disease process and its effects. The primary treatment for OA knee conservatively is physiotherapy which includes strength training, modalities, knee bracing, resistance training and Kinesiotaping. Resistance exercise can reduce knee pain severity and leg strength in participants with symptomatic knee OA. Exercise interventions using free weights or machines have generally focused on movements with concentric muscle contractions. Previous interventions were developed based on loads lifted during the concentric phase.

Kinesiotape (KT), is an elastic woven-cotton strip with a heat- sensitive acrylic adhesive structure.

Eligibility criteria: Inclusion Criteria:

* Adults of age 50- 60 years
* Presence of OA of the knee (using American College of Rheumatology criteria) for ≥6 months
* Knee pain due to tibiofemoral knee OA not from Patellofemoral OA
* Bilateral standing anterior-posterior radiograph demonstrating Kellgren and Lawrence OA grade 2 or 3

Exclusion Criteria:

* Knee surgery within last 12 months
* Lumber radiculopathy
* Vascular claudication
* Anterior knee pain due to diagnosed Patellofemoral syndrome/ chondromalacia
* Administered corticosteroid or hyaluronic injections within 3 months
* Any other MSK limitations
* Any cardiovascular problems

Primary outcomes:
measure: Temporo-spatial Gait Parameters:
timeFrame: 6 week
Secondary outcomes:
measure: Numeric Pain Rating Score (NPRS):
timeFrame: 6 week
measure: Functional Status (WOMAC Questionnaire):
timeFrame: 6 week
measure: Strength
timeFrame: 6 week
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Physio Experts Clinic
state: Capital
Study officials:
affiliation: Riphah International University
name: Aisha Razzaq, MSPT-OMPT
role: PRINCIPAL_INVESTIGATOR
References: