Clinical trial NCT04254952: Turkish Version of Nijmegen Questionnaire
Official title: The Validity and Reliability of the Turkish Version of the Nijmegen Questionnaire in Evaluating Respiratory Dysfunction in Asthmatic Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hyperventilation Syndrome
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2020-02-05
Enrollment: 54
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Asthmatic patients

Brief summary: The study aims to provide Turkish version of Nijmegen Questionnaire for the evaluation of respiratory dysfunction in asthmatic subjects. The incidence of hyperventilation syndrome in asthmatic patients can be determined with the results of the study.

Detailed description: Nijmegen Questionnaire allows to assess and identify respiratory symptoms and dysfunction, and to assess unexplained respiratory symptoms and symptoms of hyperventilation syndrome. Determining whether Turkish version of Nijmegen Questionnaire is a valid and reliable tool in asthmatic individuals will guide researchers for further studies on identifying appropriate treatment approaches for the patient and developing different treatment strategies. Hyperventilation syndrome is a recognized form of respiratory dysfunction associated with biochemical factors. Hyperventilation syndrome is defined as breathing above the body's metabolic requirements. This results in decreased carbon dioxide pressure in the arterial blood, respiratory alkalosis, and increased symptoms. Complex symptoms such as shortness of breath, chest tightness, paresthesia, anxiety, and dizziness may occur. There is no laboratory test which is the gold standard in the diagnosis of hyperventilation syndrome. If it is concluded that the Turkish version of the Nijmegen Questionnaire is a valid and reliable test in individuals with asthma, a new tool will be introduced to the literature for the evaluation of pulmonary dysfunction in asthmatic individuals.

Eligibility criteria: Inclusion Criteria:

* Having mild to moderate clinically stable asthmatic patients
* Being able to cooperate
* Being 18 years old or older

Exclusion Criteria:

* Having severe orthopedic, neurological, cardiovascular disorders or cognitive problems
* Unable to cooperte

Primary outcomes:
measure: Dyspnea perception
timeFrame: 1st day
measure: Breathe-holding time
timeFrame: 1st day
measure: End-tidal CO2 measurement
timeFrame: 1st day
measure: Asthma control test
timeFrame: 1st day
measure: Nijmegen Questionnaire
timeFrame: 1st day
Secondary outcomes:
measure: Quality of life questionnaire
timeFrame: 1st day
measure: Disease-specific quality of life
timeFrame: 1st day
measure: Assessment of anxiety and depression
timeFrame: 1st day
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Aslihan Cakmak
Study officials:
affiliation: Hacettepe University
name: Deniz Inal-Ince, Prof
role: STUDY_DIRECTOR
affiliation: Hacettepe University
name: Gul Karakaya, Prof
role: PRINCIPAL_INVESTIGATOR
affiliation: Hacettepe University
name: Aslihan Cakmak, MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Hacettepe University
name: Senem Simsek, MSc
role: PRINCIPAL_INVESTIGATOR
References: