Clinical trial NCT01507415: Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?
Official title: Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbation if COPD?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Respiratory Tract Diseases
Lung Diseases
Lung Diseases, Obstructive
Bronchitis, Chronic
Pulmonary Emphysema
Disease Progression
Keywords: Cohort Studies
Longitudinal Studies
Patient Readmission
Hospitalization
Disability Evaluation
Lead sponsor: Royal Brompton & Harefield NHS Foundation Trust
Sponsor class: OTHER
Collaborators: name: Medical Research Council
name: The Hillingdon Hospitals NHS Foundation Trust
name: West Hertfordshire Hospitals NHS Trust
First posted: 2012-01-10
Enrollment: 226
Sex: ALL
Minimum age (years): 35
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Any patient hospitalised with an acute exacerbation of COPD. Cohorts will be recruited from local District General Hospitals with Acute Admissions Units and Accident \& Emergency Departments.

Brief summary: This study aims to evaluate simple tests of physical function in hospitalised patients with chronic obstructive pulmonary disease (COPD) and to assess whether they can predict future hospital readmission. The Short Physical Performance Battery (SPPB) is a simple test of standing balance, usual walking speed (4-metre gait speed) and ability to stand from a chair, which reflects global physical functioning and frailty.

We hypothesise that the SPPB or 4-metre gait speed can predict future hospital readmissions.


Eligibility criteria: Inclusion Criteria:

* Hospital admission with an exacerbation of COPD
* Must have capacity to consent
* Able to walk

Exclusion Criteria:

* Co-morbibities that limit walking ability
* Co-morbidities that make walking unsafe

Primary outcomes:
measure: Hospital readmission rate
timeFrame: 3 months
Secondary outcomes:
measure: Hospital readmission rate
timeFrame: 12 months
measure: Time to first hospital readmission
timeFrame: 12 months
measure: Hospital Bed days
timeFrame: 12 months
Other outcomes:
Locations:
city: Uxbridge
country: United Kingdom
facility: Hillingdon Hospital
city: Watford
country: United Kingdom
facility: Watford General Hospital
Study officials:
affiliation: NIHR Respiratory Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust
name: William DC Man, MRCP PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Volpato S, Cavalieri M, Sioulis F, Guerra G, Maraldi C, Zuliani G, Fellin R, Guralnik JM. Predictive value of the Short Physical Performance Battery following hospitalization in older patients. J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):89-96. doi: 10.1093/gerona/glq167. Epub 2010 Sep 22.
citation: Nolan CM, Kon SSC, Patel S, Jones SE, Barker RE, Polkey MI, Maddocks M, Man WD. Gait speed and pedestrian crossings in COPD. Thorax. 2018 Feb;73(2):191-192. doi: 10.1136/thoraxjnl-2017-210173. Epub 2017 May 5.
citation: Kon SS, Jones SE, Schofield SJ, Banya W, Dickson MJ, Canavan JL, Nolan CM, Haselden BM, Polkey MI, Cullinan P, Man WD. Gait speed and readmission following hospitalisation for acute exacerbations of COPD: a prospective study. Thorax. 2015 Dec;70(12):1131-7. doi: 10.1136/thoraxjnl-2015-207046. Epub 2015 Aug 17.