Clinical trial NCT04354558: French Single Centre Experience of Critically Ill Patients With Covid 19
Official title: Epidemiology and Outcomes of Critically Ill Patients With Covid 19: a French Single Centre Experience
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Epidemiology
Sars-CoV2
COVID 19
Critical Care
Prognostic
Survival
Keywords: Epidemiology
Sars-CoV2
COVID 19
critical care
prognostic
survival
Lead sponsor: Centre Hospitalier Universitaire, Amiens
Sponsor class: OTHER
First posted: 2020-04-21
Enrollment: 200
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Critically ill patients with SARS Cov2 admitted in ICU

Brief summary: Since the outbreak of a syndrome of acute respiratory distress associated to a novel coronavirus 2 (SARS-Cov2) that began in China, Europe and France have to face a sanitary emergency with critically care support when the patient evolves to an acute respiratory distress (ARDS). In the context of supply shortages (ventilators, bed capacities) that countries have to deal with, data were lacking of characteristics and outcomes of patients admitted to intensive care unit (ICU). the purpose of this project is to report the epidemiology and the outcomes of a French cohort of critically ill patients with SARS-Cov2


Eligibility criteria: Inclusion Criteria:

* 18 years old
* patient with positive rRT PCR of SARS Cov2 on a sample of nasopharyngeal swab
* admission in intensive care unit

Exclusion Criteria:

* patient under 18 years old

Primary outcomes:
measure: Variation of age between critically ill patients with SARS Cov2 admitted in ICU with non critically ill patients with SARS Cov2 admitted in ICU
timeFrame: from day 1 of admission
measure: Variation of medical history between critically ill patients with SARS Cov2 admitted in ICU with non critically ill patients with SARS Cov2 admitted in ICU
timeFrame: from day 1 of admission
measure: Variation of chronic drug used between critically ill patients with SARS Cov2 admitted in ICU with non critically ill patients with SARS Cov2 admitted in ICU
timeFrame: from day 1 of admission
measure: Variation of chest CT scan at admission, between critically ill patients with SARS Cov2 admitted in ICU with non critically ill patients with SARS Cov2 admitted in ICU
timeFrame: from day 1 of admission
measure: Variation of respiratory support at ICU admission, between critically ill patients with SARS Cov2 admitted in ICU with non critically ill patients with SARS Cov2 admitted in ICU
timeFrame: from day 1 of admission
Secondary outcomes:
Other outcomes:
Locations:
city: Amiens
country: France
facility: CHU Amiens
Study officials:
affiliation: CHU Amiens
name: Osama Abou Arab, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Beyls C, Hermida A, Bohbot Y, Martin N, Viart C, Boisgard S, Daumin C, Huette P, Dupont H, Abou-Arab O, Mahjoub Y. Automated left atrial strain analysis for predicting atrial fibrillation in severe COVID-19 pneumonia: a prospective study. Ann Intensive Care. 2021 Dec 7;11(1):168. doi: 10.1186/s13613-021-00955-w.