Clinical trial NCT06881316: Caffeine vs. Carbohydrate Mouth Rinsing in Soccer
Official title: Caffeine vs. Carbohydrate Mouth Rinsing in Soccer: Effects on Passing Performance and Psychophysiological Responses in Youth Players
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Performance
Soccer
Caffeine and Carbohydrate
Cognitive Function
Technical Skill
Keywords: Performance
caffeine mouth-rinsing
carbohydrate mouth-rinsing
cognitive-motor function
technical skill execution
Lead sponsor: Tokat Gaziosmanpasa University
Sponsor class: OTHER
First posted: 2025-03-18
Enrollment: 20
Sex: MALE
Minimum age (years): 14
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Crossover Assignment
Primary purpose: TREATMENT

Brief summary: The present study evaluated the influence of carbohydrate mouth-rinsing (CHO-MR), caffeine mouth-rinsing (CAF-MR), and control-substance mouth rinses on Loughborough soccer passing test (LSPT) performance. The study participants were involved in a randomized, double-blind, repeated-measures design that employed four sessions (familiarization, CHOMR, CAFMR, and CONT) over ten days at a testing facility. Participants took part in six test sessions 72 hours apart. In the CHO group, 6% w/v glucose solution was used. In the CAFF group, 6% w/v glucose solution was used. CONT group, only exercise was performed without any condition.

Detailed description: Participants were involved in a randomized, double-blind, repeated-measures design that employed four sessions (familiarization, LSPTCHO, LSPTCAFF, and LSPTCONT) over ten days at a testing facility. The initial session was an orientation, allowing participants to acclimate to the LSPT protocol and provide written informed consent. This session used water as a mouth rinse. Anthropometric data were also collected. Before the LSPT, participants completed 15-minute standardized warm-up sections, including jogging, sprinting, and integrating soccer-specific actions. The participants were asked to complete the LSPT at any time. During the tests, participants were blinded to the test scores. The following three sessions were test trials conducted between 15.00 h and 17.00 h at 32°C and 40% humidity. The participants performed the LSPT 72 h apart, LSPTCHO (6% w/v glucose solution), LSPTCAFF (1.2% w/v caffeine solution), and LSPTCONT conditions. Caffeine and CHO solutions were prepared in an equivalent saccharin base to ensure indistinguishability within the Falcon Sterile Tube and agitated for 30 seconds on a vortex mixer. Participants were instructed to avoid intense activity 24 hours before testing, observe a 2-hour fast before sessions, and abstain from caffeinated products on test days. All the test sessions were performed at 32°C and 40% humidity.

Eligibility criteria: Inclusion Criteria:

* Being healthy
* Male soccer players
* Willing to maintain the intervention for all sessions

Exclusion Criteria:

* Being under 14 years old
* Having a chronic disease
* Contraindication for caffeine mouth-rinsing (CAF-MR)
* Contraindication for carbohydrate mouth-rinsing (CHO-MR)
* Contraindications for exercise

Primary outcomes:
measure: Psychophysiological Responses-Heart Rate
timeFrame: From baseline to the end of treatment at 2 weeks
measure: Psychophysiological Responses-Rating of Perceived Exertion
timeFrame: From baseline to the end of treatment at 2 weeks
measure: Psychophysiological Responses-Enjoyment-Brunel mood of states
timeFrame: From baseline to the end of treatment at 2 weeks
measure: Loughborough Soccer Passing Test (LSPT)
timeFrame: From baseline to the end of treatment at 2 weeks
Secondary outcomes:
measure: Anthropometric Measurements 1
timeFrame: Baseline
Other outcomes:
measure: Anthropometric Measurements 2
timeFrame: Baseline
measure: Anthropometric Measurements 3
timeFrame: Baseline
Locations:
city: Tokat
country: Turkey
facility: Tokat Gaziosmanpasa Universty
Study officials:
affiliation: +905325452848
name: Ersan Arslan, Doctorate
role: STUDY_CHAIR
References:
citation: Soylu Y, Ramazanoglu F, Arslan E, Clemente FM. Effects of mental fatigue on the psychophysiological responses, kinematic profiles, and technical performance in different small-sided soccer games. Biol Sport. 2022 Oct;39(4):965-972. doi: 10.5114/biolsport.2022.110746. Epub 2021 Dec 30.
citation: Soylu Y, Chmura P, Arslan E, Kilit B. The Effects of Carbohydrate Mouth Rinse on Psychophysiological Responses and Kinematic Profiles in Intermittent and Continuous Small-Sided Games in Adolescent Soccer Players: A Randomized, Double-Blinded, Placebo-Controlled, and Crossover Trial. Nutrients. 2024 Nov 15;16(22):3910. doi: 10.3390/nu16223910.