Clinical trial NCT05384639: Dual-task Cycling System on Cognitive Function for the Elderly
Official title: Simultaneous Dual-Task Cycling Exercise Training on Cognitive Function for the Elderly
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Cognitive Impairment
Lead sponsor: Chinese University of Hong Kong
Sponsor class: OTHER
Collaborators: name: Innovation and Technology Commission, Hong Kong
First posted: 2022-05-20
Enrollment: 30
Sex: ALL
Minimum age (years): 65
Maximum age (years): 80
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This project aims to develop a new dual-task stationary cycling system that can monitor and provide feedback on the aerobic exercise intensity, while administrating appropriate cognitive trainings targeting various cognitive sub domains through a screen in front of the user.

The proposed system is designed to train the brain with cognitive tasks and the body with aerobic exercises at the same time. The difficulties of the cognitive tasks are controlled by the users' previous performances on these tasks so that they wouldn't be too easy nor too difficult. Similarly, the intensity of the aerobic exercise will be monitored through an optical encoder for the cycling cadence, two power meters for the force output on the two pedals, as well as a heart rate monitor for the users' physiological response. Constant feedback is being provided to the users so that they will exercise at the correct intensity to provide the greater cardiovascular and cognitive benefits.


Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of MCI or cutoff at 2 \< n \< 16 th percentile MoCA score according to the level of education and age
* Sufficient cognitive ability to follow simple instructions
* Able to understand content and purpose of the study
* Conscious and in stable physical condition

Exclusion Criteria:

* Any additional medical or psychological condition that would affect their ability to comply with the study protocol, e.g., a significant orthopaedic or chronic pain condition; or
* Severe hip, knee or ankle contracture that would preclude the passive range of motion of the leg
* Uncontrolled Cardiac issues

Primary outcomes:
measure: The Montreal Cognitive Assessment, Hong Kong Version (HK-MoCA)
timeFrame: Within one month after the last training session
Secondary outcomes:
measure: Trail Making Test
timeFrame: Within one month after the last training session
measure: 6 Minutes Walk Test
timeFrame: Within one month after the last training session
measure: 5 times Sit to Stand
timeFrame: Within one month after the last training session
measure: 10 meters walk Test
timeFrame: Within one month after the last training session
measure: Graded Heart-rate Assessment
timeFrame: Within one month after the last training session
Other outcomes:
Locations:
city: Shatin
country: Hong Kong
facility: Department of Biomedical Engineering, The Chinese University of Hong Kong
Study officials:
affiliation: Department of Biomedical Engineering, The Chinese University of Hong Kong
name: Raymond Tong, PhD
role: PRINCIPAL_INVESTIGATOR
References: