Clinical trial NCT05912985: Three Different Oxygenation Strategies in Bronchoscopy Procedures Under Sedation
Official title: Comparison of Three Different Oxygenation Strategies Consisting of Nasal Cannula, Modified Nasopharyngeal Cannula and HFNO (High Flow Nasal Oxygen) in Bronchoscopy Procedures Under Sedation
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Bronchoscopy
Lead sponsor: Ankara City Hospital Bilkent
Sponsor class: OTHER
First posted: 2023-06-22
Enrollment: 252
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients admitted to the bronchoscopy unit for the procedure

Brief summary: The purpose of study aims to determine which of the three different oxygenation strategies, including nasal cannula, modified nasopharyngeal cannula, and HFNO groups, is safer in patients undergoing bronchoscopy under sedation.

Detailed description: The patients will be evaluated in the anesthesia polyclinic before the procedure, routine preparation will be made, and written informed consent will be obtained. After being informed about the study and potential risks, all patients who gave written informed consent will be enrolled in the study by recording their demographic information after determining whether they are eligible to participate in the study. In addition, STOP-BANG and FRAIL fragility questionnaires will be administered to the patients. Which oxygenation method should be used which patient will be left to the decision of the Anesthesiologist; The oxygenation tools used in the bronchoscopy unit are nasal cannula, modified nasopharyngeal cannula, and HFNO. When the patients are taken to the procedure room, anesthesia management will be applied by the standard working order of the anesthesia clinic. In addition to non-invasive arterial blood pressure monitoring, 5-channel ECG and pulse oximetry, and standard hemodynamic monitoring, Bispectral Index (BIS) monitoring will be performed. During the process, oxygen saturation will be continuously monitored and the lowest value will be recorded. Interventions made in cases of low oxygen saturation will also be recorded. At the end of the procedure, the patient will be taken to the recovery unit after waking up.

Eligibility criteria: Inclusion Criteria:

* All patients undergoing bronchoscopy

Exclusion Criteria:

* Do not have the ability to read, understand and sign the consent form
* Pregnancy
* Contraindications to anesthetic drugs
* Hemodynamically unstable patients
* Having a peripheral vascular disease
* Intubated patients
* Patients with tracheostomy

Primary outcomes:
measure: desaturation rate during processing
timeFrame: during the procedure, an average of 1 hour
Secondary outcomes:
measure: rate of use of the jaw thrust maneuver during the procedure
timeFrame: during the procedure, an average of 1 hour
measure: rate of airway usage during the process
timeFrame: during the procedure, an average of 1 hour
Other outcomes:
measure: Desaturation rate in patients with a high risk of Osas according to the stop-bang score
timeFrame: before the procedure, 2 minutes
measure: Desaturation rate in patients with higher frailty scores than frail fragility scores
timeFrame: before the procedure, 2 minutes
Locations:
city: Ankara
country: Turkey
facility: Ankara Bilkent City Hospital
state: Çankaya
Study officials:
affiliation: Ankara City Hospital Bilkent
name: süleyman taş
role: PRINCIPAL_INVESTIGATOR
References: