Clinical trial NCT04099316: Effects of Eccentric Training Intervention in Older Adults
Official title: Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Sarcopenia
Keywords: Aging
Eccentric training
Muscle strength
Physical function
Sarcopenia
Lead sponsor: Seoul National University Bundang Hospital
Sponsor class: OTHER
Collaborators: name: National Research Foundation of Korea
First posted: 2019-09-23
Enrollment: 27
Sex: ALL
Minimum age (years): 60
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Sarcopenia leads to loss of muscle mass and muscle strength during the aging process. It has been reported that eccentric training has some positive effects on the preservation of eccentric strength, with less delayed onset muscle soreness (DOMS) in older groups, and lower metabolic costs.

Detailed description: This is prospective study. The goals of this study are to:

1. Examine the effects of eccentric training on physical function (gait speed, stair climb, chair stand) in older adults.
2. Examine the effects of eccentric training on muscle strength (Isometric strength, Isokinetic strength, power) in older adults.

Eligibility criteria: Inclusion Criteria:

* Subjects who can agree voluntarily
* Older men/women: Age (60 - 80 yrs)

Exclusion Criteria:

* Uncontrolled hypertension
* Acute coronary syndrome
* Subjects who took drugs which can affects neuromuscular system
* Subjects who cannot agree voluntarily

Primary outcomes:
measure: Gait speed
timeFrame: Change from baseline gaitspeed at 8 weeks
measure: Stair climb
timeFrame: Change from baseline stair climb at 8 weeks
measure: Chair stand
timeFrame: Change from baseline chair stand at 8 weeks
Secondary outcomes:
measure: Isokinetic knee strength
timeFrame: Change from baseline isokinetic knee strength at 8 weeks
measure: Isometric knee strength
timeFrame: Change from baseline isometric knee strength at 8 weeks
measure: Power
timeFrame: Change from baseline power at 8 weeks
Other outcomes:
Locations:
city: Seongnam
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
state: Geyonggi
Study officials:
References:
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