Clinical trial NCT01997970: NEAT - Prevention and Treatment of Overweight and Obesity.
Official title: Non-exercise Activity Thermogenesis (NEAT) - Prevention and Treatment of Overweight and Obesity
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Overweight
Obesity
Keywords: NEAT
Treadmill desk
Lead sponsor: Umeå University
Sponsor class: OTHER
First posted: 2013-11-28
Enrollment: 80
Sex: ALL
Minimum age (years): 40
Maximum age (years): 67
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will investigate the effect on Non-exercise Activity Thermogenesis (NEAT) when implementing active workstation at offices compared to conventional office work. The primary hypothesis is that this implementation will lead to a significant increase in time spent walking per day.

Detailed description: NEAT consists of the energy expenditure of the physical activities that are non sporting-like and that we perform in our everyday life, such as walking, cleaning, shoveling snow etc. Which occupation we have play a big role in how much we are able to active our NEAT during our days and those who have more active jobs can expend up to 1500kcal more per day than those with sedentary jobs.

This study aims to try and increase NEAT at offices where sedentary time often is high. Participants will be randomized to either an intervention group or to a control group. Participants in the control group will continue to work at their regular desk, but will receive an individual health talk in the beginning of the study where diet and physical activity recommendations will be discussed.Participants in the intervention group will receive the same individual health talk and a treadmill desk, which they will use for 12 months at self-selected speed. They will be recommended to walk on the treadmill for at least 1 hour per day.

Eligibility criteria: Inclusion Criteria:

* Office workers with mainly sedentary tasks
* BMI 25-40

Exclusion Criteria:

* Severe depression and/or anxiety
* Exhaustion disorder
* Diabetes Mellitus
* Severe cardiovascular disease
* Severe kidney disease
* Musculoskeletal disorders that prohibit walking on a treadmill
* Contraindications for physical activity
* Thyroidea illness
* Pregnancy

For fMRI-study, additional exclusion criteria are:

* Implanted metal- or electrical devices
* Pregnancy
* Extraneous metal pieces in the body

Primary outcomes:
measure: Change from baseline in physical activity and sedentariness at 12 months
timeFrame: Baseline, 12 months
Secondary outcomes:
measure: Change from baseline in metabolism at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in anthropometrics at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in body composition at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in musculoskeletal pain at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in stress at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in depression/anxiety at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in Quality of Life at 12 months
timeFrame: Baseline, 12 months
measure: Change from baseline in cognitive Function and functional brain response at 12 months
timeFrame: Baseline, 12 months
measure: Qualitative interview study
timeFrame: 12 months
Other outcomes:
Locations:
city: Umeå
country: Sweden
facility: Umeå University
Study officials:
affiliation: Umeå University
name: Tommy Olsson, Professor
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bergman F, Matsson-Frost T, Jonasson L, Chorell E, Sorlin A, Wennberg P, Ohberg F, Ryberg M, Levine JA, Olsson T, Boraxbekk CJ. Walking Time Is Associated With Hippocampal Volume in Overweight and Obese Office Workers. Front Hum Neurosci. 2020 Aug 20;14:307. doi: 10.3389/fnhum.2020.00307. eCollection 2020.
citation: Bergman F, Wahlstrom V, Stomby A, Otten J, Lanthen E, Renklint R, Waling M, Sorlin A, Boraxbekk CJ, Wennberg P, Ohberg F, Levine JA, Olsson T. Treadmill workstations in office workers who are overweight or obese: a randomised controlled trial. Lancet Public Health. 2018 Nov;3(11):e523-e535. doi: 10.1016/S2468-2667(18)30163-4. Epub 2018 Oct 12.
citation: Bergman F, Boraxbekk CJ, Wennberg P, Sorlin A, Olsson T. Increasing physical activity in office workers--the Inphact Treadmill study; a study protocol for a 13-month randomized controlled trial of treadmill workstations. BMC Public Health. 2015 Jul 10;15:632. doi: 10.1186/s12889-015-2017-6.