Clinical trial NCT04364516: Retrospective Observational Registry of Patients With Atrial Fibrillation From Vigo´s Health Area
Official title: Retrospective Observational Registry of Patients With Atrial Fibrillation From Vigo´s Health Area (Registro Observacional Retrospectivo de Pacientes Con Fibrilación Auricular Del Área de Vigo)
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Atrial Fibrillation
Keywords: Atrial Fibrllation; Anticoagulation; Bleeding; Embolism.
Lead sponsor: Hospital Álvaro Cunqueiro
Sponsor class: OTHER
First posted: 2020-04-28
Enrollment: 15000
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients with atrial fibrillation from Health Area of Vigo

Brief summary: Registry of all consecutive patients with atrial fibrillation from Heath Area of Vigo, since 2013 to 2020, in order to study therapy, mortality, cardiovascular complications and bleeding events.

Detailed description: Retrospective observational registry of patients diagnosed of atrial fibrillation between 2013 and 2020. Clinical, analytical and echocardiographic data will be recorded, as well as therapeutic prescription information. Data on mortality and cardioembolic and hemorrhagic events will be collected during follow-up. The aim is to study the prevalence and incidence of atrial fibrillation, the anticoagulant treatment according to cardioembolic risk, the thromboembolic events and hemorrhagic events, the risk of mortality (Cardiovascular, Non-Cardiovascular), the contemporary management (Rhythm control versus frequency control strategy), and other complications, such as heart failure, acute coronary syndrome or cancer.

Eligibility criteria: Inclusion Criteria:

* All patients with confirmed diagnoses of atrial fibrillation by ECG.

Exclusion Criteria:

* None

Primary outcomes:
measure: Mortality
timeFrame: Follow-up (3 years)
Secondary outcomes:
measure: Bleeding
timeFrame: Follow-up (3 years)
measure: Embolism
timeFrame: Follow-up (3 years)
Other outcomes:
Locations:
city: Vigo
country: Spain
facility: Department of Cardiology, Hospital Álvaro Cunqueiro
state: Pontevedra
Study officials:
affiliation: University Hospital Alvaro Cunqueiro, Vigo, Spain
name: EMAD ABU ASSI, PhD, MD
role: STUDY_DIRECTOR
affiliation: University Hospital Alvaro Cunqueiro, Vigo, Spain
name: SERGIO RAPOSEIRAS ROUBIN, PhD, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: University Hospital Alvaro Cunqueiro, Vigo, Spain
name: ANDRES IÑIGUEZ ROMO, PhD, MD
role: STUDY_CHAIR
References:
citation: Dominguez-Erquicia P, Raposeiras-Roubin S, Abu-Assi E, Bouzon-Iglesias P, Parada-Barcia JA, Lizancos-Castro A, Gonzalez-Garcia A, Noriega-Caro VA, Ledo-Pineiro A, Iglesias-Otero C, Gonzalez-Bermudez I, Iniguez-Romo A. Comparison of Outcomes in Patients With Atrial Fibrillation Under Oral Anticoagulation Therapy Analyzed by Body Weight (<60, 60 to 100, and >100 kg). Am J Cardiol. 2022 Dec 1;184:41-47. doi: 10.1016/j.amjcard.2022.07.028. Epub 2022 Sep 27.
citation: Raposeiras-Roubin S, Abu-Assi E, Lizancos Castro A, Barreiro Pardal C, Melendo Viu M, Cespon Fernandez M, Blanco Prieto S, Rossello X, Ibanez B, Filgueiras-Rama D, Iniguez Romo A. Nutrition status, obesity and outcomes in patients with atrial fibrillation. Rev Esp Cardiol (Engl Ed). 2022 Oct;75(10):825-832. doi: 10.1016/j.rec.2022.01.006. Epub 2022 Mar 9. English, Spanish.
citation: Cespon-Fernandez M, Raposeiras-Roubin S, Abu-Assi E, Melendo-Viu M, Garcia-Campo E, Iniguez-Romo A. Renin-Angiotensin System Inhibitors Prognostic Benefit in Older Patients with Atrial Fibrillation. J Am Med Dir Assoc. 2021 Oct;22(10):2190-2195. doi: 10.1016/j.jamda.2021.01.063. Epub 2021 Feb 16.