Clinical trial NCT06854419: Efficacy Evaluation of Blood Peach Extract and Rose Apple Extract on Skin
Official title: Efficacy Evaluation of Blood Peach Extract and Rose Apple Extract on Skin
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Dermatology
Keywords: skin analysis
skin care products
Lead sponsor: TCI Co., Ltd.
Sponsor class: INDUSTRY
First posted: 2025-03-03
Enrollment: 90
Sex: FEMALE
Minimum age (years): 20
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Evaluate the effects of blood peach extract drink and rose apple extract drink on enhancing hemoglobin and iron levels, and improving skin health.


Eligibility criteria: Inclusion Criteria:

* Healthy adult females aged 20 to 65;
* Preferably those with pale complexion or signs of iron deficiency anemia.

Exclusion Criteria:

* Currently undergoing or having undergone any medical beauty treatments within the past month (including skincare, laser treatments, chemical peel, injections, or cosmetic surgery);
* Outdoor workers (exposed to sunlight for more than 5 hours daily);
* Pregnant, breastfeeding, or planning to become pregnant during the trial (self-reported);
* Individuals with heart, liver, kidney, endocrine, or other significant organic diseases (self-reported);
* Individuals who have undergone major surgery (according to medical history);
* Long-term medication users;
* Individuals with mental health disorders;
* Those who are already regularly taking iron supplements;
* Faculty or staff members who are currently enrolled in the principal investigator's courses.

Primary outcomes:
measure: the volume of skin wrinkles
timeFrame: Volume change from Baseline skin wrinkles at 8 weeks
measure: the roughness of skin texture
timeFrame: Rating skin roughness from Baseline skin texture at 8 weeks
Secondary outcomes:
measure: the change of skin elasticity
timeFrame: Change from Baseline skin elasticity at 8 weeks
measure: the change of skin collagen density
timeFrame: Change from Baseline skin collagen density at 8 weeks
measure: the change of skin pores
timeFrame: Change from Baseline skin pores at 8 weeks
measure: the change of skin tone
timeFrame: Change from Baseline skin tone at 8 weeks
measure: the change of skin hydration
timeFrame: Change from Baseline skin hydration at 8 weeks
measure: the change of skin melanin/erythema index
timeFrame: Change from Baseline skin melanin/erythema index at 8 weeks
measure: the change of skin redness
timeFrame: Change from Baseline skin redness at 8 weeks
measure: the change of lip redness
timeFrame: Change from Baseline lip redness at 8 weeks
measure: the change of Red Blood Cells (RBC) Count of blood
timeFrame: Change from Baseline RBC count at 8 weeks
measure: the change of hemoglobin level of blood
timeFrame: Change from Baseline hemoglobin level at 8 weeks
measure: the change of mean corpuscular volume (M.C.V) level of blood
timeFrame: Change from Baseline M.C.V level at 8 weeks
measure: the change of mean corpuscular hemoglobin concentration (M.C.H.C) level of blood
timeFrame: Change from Baseline M.C.H.C level at 8 weeks
measure: the change of ferrous level of blood
timeFrame: Change from Baseline ferrous level at 8 weeks
measure: the change of ferritin level of blood
timeFrame: Change from Baseline ferritin level at 8 weeks
measure: the change of Total Iron Binding Capacity (TIBC) level of blood
timeFrame: Change from Baseline TIBC level at 8 weeks
measure: the change of unsaturated iron-binding capacity (UIBC) level of blood
timeFrame: Change from Baseline UIBC level at 8 weeks
Other outcomes:
measure: the change of liver function biomarkers (AST, ALT) of blood
timeFrame: change from Baseline liver function biomarkers at 8 weeks
measure: the change of renal function biomarkers (creatinine, BUN) of blood
timeFrame: change from Baseline renal function biomarkers at 8 weeks
measure: the change of fasting glucose level of blood
timeFrame: change from Baseline fasting glucose level at 8 weeks
measure: the change of Advanced glycation end products (AGEs) level of blood
timeFrame: change from Baseline AGEs level at 8 weeks
measure: The change of self-assessment skin and metabolic circulation condition
timeFrame: Change from Baseline skin and metabolic circulation condition at 8 weeks
Locations:
city: Taichung City
country: Taiwan
facility: China Medical University of Department of Cosmeceutics
Study officials:
affiliation: China Medical University of Department of Cosmeceutics
name: Hsiu-Mei Chiang
role: PRINCIPAL_INVESTIGATOR
References: