Clinical trial NCT06700265: Ultrasound Airway Examination as a Tool for Detection of Difficult Intubation in Adult Patients
Official title: Ultrasound Airway Examination as a Tool for Detection of Difficult Intubation in Adult Patients
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Difficult Airway
Keywords: airway ultrasound
Lead sponsor: National Cancer Institute, Egypt
Sponsor class: OTHER
First posted: 2024-11-21
Enrollment: 246
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: all population undergoining surgical operation requiring general anesthesia and endotracheal intubation

Brief summary: the goal of the observational study to measure the effectiveness of neck ultrasound in prediction of difficult intubation in adult patients

Detailed description: All participant undergoing elective surgery under general anesthesia will go a detailed preoperative sonographic assessment by the anesthesiologist who has experience in airway ultrasound for measurement of Hyomental distance, thyrohyoid distance, thyroid cricoid, anterior soft tissue thickness at levels of hyoid bone, cricoid cartilage and vocal cord and all measurement will be measured in neutral and sniffing position.

after induction of general anesthesia intubation will done by macintosh laryngoscope and degree of difficulty of intubation will be measured by cormack-lehane classification without any external manipulation

Eligibility criteria: Inclusion Criteria:

* Adult patients above18 years old
* Both sex
* Requiring general anesthesia with endotracheal intubation

Exclusion Criteria:

* Emergency surgery,
* patients with limited mouth, head or neck movement,
* patients with temporomandibular joint impairment,
* fracture or tumors of mandible,
* patients requiring awake intubation,
* uncooperative patients,
* any cervical spine limitation movement
* neck swelling or tumor
* Prominent teeth deformities.

Primary outcomes:
measure: measurement of effectiveness of neck ultrasound use of ultrasound measurement in prediction of difficult intubation
timeFrame: 30 min after ultrasound measurements at time of induction of anesthesai
Secondary outcomes:
measure: Hyomental distance in neutral position
timeFrame: 30 min before operation
measure: Throhyoid distance in neutral position
timeFrame: 30 min before operation
measure: Cricothyriod distance in neutral position
timeFrame: 30 min before operation
measure: Anterior soft tissue thickness at level of hyoid bone in neutral position
timeFrame: 30 min before opeqrtio
measure: Anterior soft tissue thickness at level of epiglottis in neutral position
timeFrame: 30 min befor operation
measure: Anterior soft tissue thickness at level of vocal cord in neutral position
timeFrame: 30 min before operation
measure: Hyomental distance in sniffing position
timeFrame: 30 min before operation
measure: Thyrohyoid distance in sniffing position
timeFrame: 30 min before operation
measure: Cricothyroid distance in sniffing position
timeFrame: 30 minutes before operation
measure: Anterior soft tissue thickness at level of hyoid bone in sniffing position
timeFrame: 30 min before operation
measure: Anterior soft tissue thickness at level of epiglottis in sniffing position
timeFrame: 30 min before operation
measure: Anterior soft tissue thickness at level of vocal cord in sniffing position
timeFrame: 30 min before operation
Other outcomes:
measure: Age
timeFrame: 30 min before operation
Locations:
Study officials:
affiliation: national cancer institute in egypt
name: ayman ali ghoneim, MD in anesthesia
role: STUDY_DIRECTOR
References:
citation: Parameswari A, Govind M, Vakamudi M. Correlation between preoperative ultrasonographic airway assessment and laryngoscopic view in adult patients: A prospective study. J Anaesthesiol Clin Pharmacol. 2017 Jul-Sep;33(3):353-358. doi: 10.4103/joacp.JOACP_166_17.
citation: Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Airway physical examination tests for detection of difficult airway management in apparently normal adult patients. Cochrane Database Syst Rev. 2018 May 15;5(5):CD008874. doi: 10.1002/14651858.CD008874.pub2.
citation: Gomes SH, Simoes AM, Nunes AM, Pereira MV, Teoh WH, Costa PS, Kristensen MS, Teixeira PM, Pego JM. Useful Ultrasonographic Parameters to Predict Difficult Laryngoscopy and Difficult Tracheal Intubation-A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021 May 28;8:671658. doi: 10.3389/fmed.2021.671658. eCollection 2021.