Clinical trial NCT06289816: Spleen Preserving Surgery for Splenic Hydatidosis: A Cohort Study on Short and Long-Term Outcomes
Official title: Minimally Invasive Spleen Preserving Surgery to Treat Primary Splenic Hydatidosis: Short and Long Term Outcomes: A Cohort Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Spleen-Preserving Surgery
Echinococcus Granulosus Infection
Hydatid Disease
Minimally Invasive Surgery
Keywords: Spleen-Preserving Surgery
Primary Splenic Hydatid Cyst
Hydatid Disease
Minimally Invasive Surgery
Echinococcus granulosus
Recurrence
Lead sponsor: Yarmouk University
Sponsor class: OTHER
First posted: 2024-03-04
Enrollment: 18
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This retrospective study involved patients diagnosed with primary splenic hydatid cysts, from January 2015 to June 2021. The study included medical records of 18 patients aged 14 years or older, diagnosed exclusively with primary, non-recurrent splenic hydatid cysts.

Exclusion criteria encompassed individuals under 14 years, patients in late pregnancy, those with recurrent cysts, extra-splenic involvement, or less than two years of postoperative follow-up.

Brief summary: This retrospective cohort study examines the effectiveness of minimally invasive spleen-preserving surgeries compared to total splenectomy for treating primary splenic hydatidosis in Jordan. Covering 18 patients from January 2015 to June 2021, the research highlights similar recurrence rates between both surgical approaches, emphasizing the benefits of spleen preservation in maintaining immune function and reducing septic risks, particularly in pediatric patients.

Detailed description: The study delves into a detailed analysis of 18 cases of primary splenic hydatid cysts treated through spleen-preserving surgeries-laparoscopic partial splenectomy, cystectomy, and cyst deroofing-augmented by albendazole therapy. It presents a comprehensive comparison based on patient demographics, symptoms, surgical details, and outcomes, including complications and recurrence rates. Findings reveal no significant statistical difference in recurrence rates between spleen-preserving methods and total splenectomy, suggesting the viability of less invasive approaches for managing this condition effectively while preserving spleen functionality and minimizing post-operative complications. The study underlines the need for individualized treatment plans and further research with larger cohorts.

Eligibility criteria: Inclusion Criteria:

* Adult patients (age 14 years or older).
* Diagnosed exclusively with primary, non-recurrent splenic hydatid cysts.

Exclusion Criteria:

* Children under 14 years of age.
* Patients in late pregnancy.
* Individuals with recurrent cysts.
* Cases with extra-splenic involvement.
* Patients with less than two years of postoperative follow-up.

Primary outcomes:
measure: Incidence of Postoperative Short-Term Complications
timeFrame: Up to 1 month post-operation
measure: Incidence of Postoperative Long-Term Complications
timeFrame: Up to 2 years post-operation
Secondary outcomes:
Other outcomes:
Locations:
city: Irbid
country: Jordan
facility: Anas Aljaiuossi
Study officials:
References: