Clinical trial NCT01545986: A Comparative Analysis of Two Types of Exercise on Outcomes Following Total Knee Arthroplasty
Official title: A Comparative Analysis of High Velocity and Standard Low Velocity Exercise Training on Rehabilitation Outcomes Following Total Knee Arthroplasty
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoarthritis, Knee
Keywords: Joint Replacement
Exercise
Power training
Lead sponsor: Helen Hayes Hospital
Sponsor class: OTHER
First posted: 2012-03-07
Enrollment: 38
Sex: ALL
Minimum age (years): 60
Maximum age (years): 89
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study was to compare the effects of two exercise programs, using low velocity (LV) and high velocity (HV) contractions, on outcomes of individuals who have undergone total knee arthroplasty (TKA). The experimental hypothesis was that individuals performing HV exercise, compared to LV, would exhibit superior outcomes.

Detailed description: The most effective type of exercise has not been identified for individuals who undergo total knee arthroplasty (TKA). High velocity (HV) exercise when compared to low velocity (LV) exercise produces greater gains in power and certain functional activities in older adults. The use of HV exercise for patients who undergo TKA has not been investigated.

Eligibility criteria: Inclusion Criteria:

* Adults aged 60- 89 years of age.
* primary unilateral TKA 10-21 days prior to the outpatient PT evaluation
* received inpatient rehabilitation at Helen Hayes Hospital

Exclusion Criteria:

* Any other lower extremity joint or back pain (not inclusive of recent Total knee arthroplasty) rated greater than four out of ten with weight-bearing
* any other lower extremity joint replacement surgery
* diagnosis of osteoporosis with history of fractures, uncontrolled hypertension, unstable cardiac or pulmonary problems, neurological disease affecting motor control, uncontrolled diabetes
* chest pain or shortness of breath on stair-climbing
* requirement of human assistance to walk in addition to the ambulation device
* inability to follow instructions to perform testing and/or exercise,
* participants who stated that they would not be available to complete 12 exercise sessions
* individual adherence with performance of a home exercise program (HEP) less than five of seven days at the end of the treatment period

Primary outcomes:
measure: Change from Baseline in Six Minute Walk Test (6MWT) at six weeks
timeFrame: 6 weeks
Secondary outcomes:
measure: Gait Abnormality Rating Scale (GARS)
timeFrame: 6 weeks
measure: Change from Baseline in Visual Analogue Scale (VAS) Pain at six weeks
timeFrame: 6 weeks
measure: Change from Baseline in Timed Up and Go Test (TUG) at six weeks
timeFrame: 6 weeks
measure: Gait Velocity
timeFrame: 6 weeks
measure: Change from Baseline in Short Form-36 (SF-36) at six weeks
timeFrame: 6 weeks
measure: Change from Baseline in Stair Climb Test at six weeks
timeFrame: 6 weeks
Other outcomes:
Locations:
city: West Haverstraw
country: United States
facility: Helen Hayes Hospital
state: New York
Study officials:
affiliation: Helen Hayes Hospital
name: Marie A. Kelly, DHS
role: PRINCIPAL_INVESTIGATOR
References: