Clinical trial NCT05030259: The Research About the ACS After Femoropopliteal Arterial Injuries
Official title: ACS After Femoropopliteal Arterial Injuries
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Acute Compartment Syndrome
Keywords: ACS
femoropopliteal arterial injuries
fasciotomy
Lead sponsor: Hebei Medical University Third Hospital
Sponsor class: OTHER
First posted: 2021-09-01
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The patients with femoropopliteal arterial injuries in our hospital who will be treated with vascular repair.

Brief summary: Crural Compartment syndrome is a well-known sequela after femoropopliteal arterial injuries in the lower extremity, particularly when there has been a long period of ischemia,need for ligation of a major vein, or when there is severe associated soft tissue.There is conteoversy in the treatment.


Eligibility criteria: Inclusion Criteria:

* patients with femoropopliteal arterial injuries
* patients older than 18 years

Exclusion Criteria:

* Patients who did not survive to discharge
* Patients with primary amputation
* patients younger than 18 years

Primary outcomes:
measure: the rate of amputation
timeFrame: up to 6 months
measure: fasciotomy performed or not
timeFrame: up to 2 weeks
Secondary outcomes:
measure: the rate of primary skin closure
timeFrame: up to 1 months
measure: hospital lengths of stay
timeFrame: up to 6 months
measure: injury mechanism of patients
timeFrame: up to 1 week
measure: the costs of hospitalization
timeFrame: up to 2 months
measure: tourniquet used or not
timeFrame: up to 1 week
measure: the time of using tourniquet
timeFrame: up to 1 week
measure: the time to surgical intervention
timeFrame: up to 1 month
measure: extremity Abbreviated Injury Scale of patients
timeFrame: up to 1 week
measure: Injury Severity Score of patients
timeFrame: up to 1 week
measure: concomitant injury of patients
timeFrame: up to 1 week
measure: time of skin closure
timeFrame: up to 1 month
measure: admission hemoglobin of patients
timeFrame: up to 1 month
measure: admission pH of patients
timeFrame: up to 1 month
measure: admission lactate of patients
timeFrame: up to 1 month
measure: postoperative lactate of patients
timeFrame: up to 1 month
measure: admission International Normalized Ratio of patients
timeFrame: up to 1 month
measure: postoperative International Normalized Ratio of patients
timeFrame: up to 1 month
measure: admission CK of patients
timeFrame: up to 1 month
measure: postoperative CK of patients
timeFrame: up to 1 month
measure: admission LDH of patients
timeFrame: up to 1 month
measure: postoperative LDH of patients
timeFrame: up to 1 month
measure: Number of Participants with Lower Extremity Arteriosclerosis Obliterans
timeFrame: up to 1 week
measure: vascular repair technique of patients
timeFrame: up to 1 week
measure: Number of Participants with sepsis
timeFrame: up to 1 month
measure: Ischemia time of patients
timeFrame: up to 1 week
measure: Postoperative knee function of patients
timeFrame: up to 6 month
Other outcomes:
Locations:
city: Shijiazhuang
country: China
facility: the Third Hospital of Hebei Medical Univesity
state: Hebei
Study officials:
affiliation: Hebei Medical University Third Hospital
name: Hou Zhiyong, Doctor
role: PRINCIPAL_INVESTIGATOR
References: