Clinical trial NCT04217915: A Survey of Management of Analgesia, Sedation and Delirium in ICU Patients in China
Official title: A Survey of Management of Analgesia, Sedation and Delirium in ICU Patients in China
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Delirium on Emergence
Analgesia
Separation
Keywords: analgesia
sedation
ICU
Delirium
Lead sponsor: China Medical University, China
Sponsor class: OTHER
Collaborators: name: The Second Affiliated Hospital of Kunming Medical University
name: First Affiliated Hospital of Kunming Medical University
name: First Affiliated Hospital of Harbin Medical University
name: The First Affiliated Hospital of Dalian Medical University
name: Peking University People's Hospital
name: Qilu Hospital of Shandong University
name: The Second Affiliated Hospital of Dalian Medical University
name: The Second Affiliated Hospital of Harbin Medical University
name: The First Hospital of Jilin University
name: General Hospital of Ningxia Medical University
First posted: 2020-01-06
Enrollment: 800
Sex: ALL
Minimum age (years): 18
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The patients were randomly selected from the ICU of the A tertiary hospitals in the major provinces and cities of China.

Brief summary: In 2018, the severe medicine branch of the Chinese Medical Association and the American Society of severe medicine successively updated the pain and sedation guidelines for severe patients (PADIS guidelines). In addition to the update of the original evaluation and management of pain and sedation and delirium, the new guidelines also increased the monitoring and management of early activities and sleep quality for severe patients. Therefore, it is necessary for us to investigate the compliance of the new guidelines for analgesia, sedation and delirium management among the medical staff of critical care, so as to find out the existing problems in the management of analgesia, sedation and delirium in critical care patients, and find solutions to improve the overall quality level of our management of critical care patients

Detailed description: The first part is to master the current situation of analgesia, sedation and delirium management of ICU patients in China. In order to understand the compliance of Chinese ICU doctors and nurses with the PADIS guidelines, a questionnaire survey was conducted with the participation of multiple centers in China, aiming at the doctors and nurses with different seniority in the critical medicine department. At the same time, the total number of critically ill patients, pain, agitation and delirium assessment tools and critical patients in 2018 were investigated The incidence of pain, agitation and delirium, the implementation of early activities, the monitoring and evaluation of sleep quality, and related interventions, including real-world clinical data such as drug treatment and non drug treatment.The second part focuses on the management of severe delirium in ICU in China. For the patients with delirium in the above survey, a further in-depth and detailed survey shall be conducted, covering the basic diseases of the patients, the occurrence time of delirium, the type of delirium, relevant risk factors, the diagnosis method of delirium, the duration of delirium, the prevention and treatment measures (including drug treatment and non drug treatment measures), and the prognosis of delirium patients .

Eligibility criteria: Inclusion Criteria:

* Age ≥ 18 years old;
* stay in ICU for more than 24 hours and have used analgesics and Sedatives.

Exclusion Criteria:

* Before entering the ICU, they had mental illness and dementia;
* coma or deep sedation could not be evaluated;
* brain injury, stroke sequelae, epilepsy and other brain diseases;
* nerious audio-visual dysfunction and unable to communicate normally.
* Pregnant and lactating women

Primary outcomes:
measure: Compliance of ICU medical staff with PADIS guidelines
timeFrame: 2020.12
Secondary outcomes:
measure: Incidence of delirium
timeFrame: 2020.12
Other outcomes:
Locations:
city: Shenyang
country: China
facility: the first hospital of China Medical University
state: Liaoning
Study officials:
affiliation: China Medical University, China
name: xiaochun ma, doctor
role: STUDY_CHAIR
References:
citation: Wang J, Peng ZY, Zhou WH, Hu B, Rao X, Li JG. A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China. Chin Med J (Engl). 2017 May 20;130(10):1182-1188. doi: 10.4103/0366-6999.205852.
citation: Morandi A, Piva S, Ely EW, Myatra SN, Salluh JIF, Amare D, Azoulay E, Bellelli G, Csomos A, Fan E, Fagoni N, Girard TD, Heras La Calle G, Inoue S, Lim CM, Kaps R, Kotfis K, Koh Y, Misango D, Pandharipande PP, Permpikul C, Cheng Tan C, Wang DX, Sharshar T, Shehabi Y, Skrobik Y, Singh JM, Slooter A, Smith M, Tsuruta R, Latronico N. Worldwide Survey of the "Assessing Pain, Both Spontaneous Awakening and Breathing Trials, Choice of Drugs, Delirium Monitoring/Management, Early Exercise/Mobility, and Family Empowerment" (ABCDEF) Bundle. Crit Care Med. 2017 Nov;45(11):e1111-e1122. doi: 10.1097/CCM.0000000000002640.