Clinical trial NCT04553874: Health Status of the Oldest-old Population
Official title: Health Status of the Oldest-old Population: a Population-based, Cohort Study
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: the Health Status of the Oldest Old
Keywords: oldest-old; epidemiology; population-based; cohort
Lead sponsor: Peking University
Sponsor class: OTHER
Collaborators: name: Beijing Tongren Hospital
First posted: 2020-09-18
Enrollment: 800
Sex: ALL
Minimum age (years): 80
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All the people aged 80 years and above in the target community in Beijing will be enrolled, and people who were hospitalized for long period (6 months or more) or at the end of their lives were excluded.

Brief summary: This study aims to investigate the health status of the oldest-old population and to explore the key factors associated with their quality of life The study will select all the elderly aged 85 years and above from Lanqiying Community, Qinghuayuan Street, Haidian District, Beijing, and enroll them after informed consent. Demographic, sociological, economic, physiological information and disease-related records will be collected through questionnaire interviews, scales, and examinations.

After the first survey, the participants will be followed for 2 years to collect information about deaths or major health events. The baseline survey will be re-conducted two years later.

Detailed description: This study is a population-based cohort study. Oldest-old people (aged 80 and over) will be enrolled.

Data collection Social economics information include: name, gender, age, nationality, marital status, personal habits, occupation, level of education, family living situation, monthly income, way to go to a doctor and medical payment, etc The health status and disease will be obtained by review the medical records as well as the narration of the subjects and their family members. We will focus on diseases with high disability mortality, high social burden. Multiple indicators or abilities will be evaluated through the scale, including life or acting ability, nutritional status, cognitive ability, psychological status, social support, quality of life self-assessment, etc., so as to comprehensively understand the comprehensive information of the participants.

Basic physical examination and special clinical examination will be performed to obtain multiple objective indicators reflecting the subject's physical function The basic health examination includes; Blood pressure, respiration, heart rate, pulse; Height, weight, waist circumference, hip circumference, arm circumference, calf circumference, grip strength, vital capacity, tooth condition, hearing condition, visual acuity, ECG, etc.

Special examinations include the blood, urine, and stool specimens. Imageological examination like MRI, fundus photography, and optical coherence tomography will also be conducted.

Eligibility criteria: Inclusion Criteria:

* All the people aged 80 years and above in the target community in Beijing

Exclusion Criteria:

* People who were hospitalized for long period (6 months or more) or at the end of their lives were excluded.

Primary outcomes:
measure: Death
timeFrame: 3 years
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Peking University Third Hosipital
state: Beijing
Study officials:
affiliation: Peking University Third Hospital
name: chun Zhang, doctor
role: PRINCIPAL_INVESTIGATOR
References: