Clinical trial NCT06001866: Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Official title: Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Developmental Language Disorder
Specific Language Impairment
Language Development
Keywords: word learning
word retrieval
preschool-aged children
Lead sponsor: Purdue University
Sponsor class: OTHER
Collaborators: name: National Institute on Deafness and Other Communication Disorders (NIDCD)
First posted: 2023-08-21
Enrollment: 27
Sex: ALL
Minimum age (years): 48
Maximum age (years): 71
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Within-participant design in which each child learns words under two conditions.
Primary purpose: BASIC_SCIENCE

Brief summary: Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and eventual economic wellbeing. Word learning is one of the principal weaknesses in these children. This project focuses on the word learning abilities of four- and five-year-old children with DLD. The goal of the project is to build on the investigators' previous work to determine whether, as has been found thus far, special benefits accrue when these children must frequently recall newly introduced words during the course of learning. The focus of the current study is verb-learning. The goal of the study is to increase children's absolute levels of learning while maintaining the advantage that repeated retrieval holds over comparison methods of learning.

Detailed description: Developmental Language Disorder (DLD) affects language learning in an estimated 7% of children. Although much of the research literature has emphasized difficulties learning grammar, children with DLD also have major deficits in vocabulary. In recent work, the investigators have been examining the benefit of retrieval practice to enhance word learning and retention in preschoolers with DLD. The rationale behind this work is grounded in the growing literature in the field of cognitive psychology which shows that repeated practice in retrieving information results in greater long-term retention than continuous study of that information without opportunities for retrieval. In addition, retrieval practice that occurs after a delay-or "spacing" between study of a word and subsequent recall attempts-can lead to stronger effects.

The investigators have explored the benefits of retrieval practice for preschoolers with DLD and with typical language development (TD), showing that recall and retention for novel words (nouns, adjectives, verbs) were greater when learned using repeated spaced retrieval (RSR) than when learned using repeated study only. Despite benefitting from RSR, children with DLD still showed lower levels of recall than children with TD, in particular in novel verb learning.

In the current study, the investigators seek to improve the absolute levels of word form recall for verbs by modifying the method used previously. Sixteen children with DLD will be recruited for this study along with 16 children with TD matched on chronological age. Using a within-subjects design, children will learn eight novel verbs, four at a time. Each set of four will be learned over two consecutive days, with two words in the RSR condition and two words in a repeated study condition. The referents for these novel words will be video-recorded transitive actions performed by actors on objects and presented on a laptop screen.

In the RSR condition, children will initially hear the word paired with a video of a novel action, immediately be asked to recall the word, and then see/hear it again. After three other words are presented, they will be asked to recall the original word again; this "3" spaced retrieval schedule will continue for the rest of the learning session. In the comparison condition, children will simply hear the words paired with a video of the novel action. In this study, during retrieval practice, children will be prompted to respond with a full sentence containing the verb.

Recall of the verbs will be tested after the learning session on the second day and one week later. At one week, children will also complete a syntactic generalization test in which they are prompted to use the novel verb in a type of sentence that is different from the one used during learning. Finally, children will complete a two-alternative recognition test.

The investigators hypothesize that novel verbs that undergo RSR during the learning period will be learned and recalled better than comparable novel verbs that are assigned to the repeated study condition. This RSR advantage will continue to be observed when the children must use the novel verbs with new actors and objects and will be seen as well in the syntactic generalization test when the children must use the novel verbs in a new sentence frame. Introducing novel verbs representing actions that can be performed on varying objects is expected to improve overall learning. In addition, by having the child produce the verbs in the context of a full sentence, the newly learned verbs should become more integrated with other sentence elements (subjects and direct objects), resulting in a richer representation in memory and consequently, greater recall, recognition, and syntactic flexibility than was observed in the previous novel verb study.

Eligibility criteria: Inclusion Criteria:

* a significant deficit in language ability (language test score below cutoff for best sensitivity/specificity) or documented age-appropriate language ability.

normal hearing no evidence of neurological damage or disease scores on tests of nonverbal intelligence above the intellectual disability range not within Autistic range on Autism screening test native English speaker (can be bilingual)

Exclusion Criteria:

* failed hearing screening known neurological damage or disease scores on tests of nonverbal intelligence below the intellectual disability range (standard score less than 75) autism spectrum disorder non-native English speaker

Primary outcomes:
measure: Word form recall accuracy (number of verbs correctly recalled)
timeFrame: 5 minutes after end of learning period
measure: Word form recall accuracy (number of verbs correctly recalled)
timeFrame: 1 week after end of learning period
measure: Accuracy of generalizing novel verb to a new syntactic frame (number of verbs used in a syntactic frame different from the one used in initial learning and recall).
timeFrame: 1 week after end of learning period
measure: Word recognition (number of words accurately identified)
timeFrame: 1 week after end of learning period
Secondary outcomes:
measure: Number of correctly identified words on Peabody Picture Vocabulary Test, 5th Ed.
timeFrame: completed at start of study
measure: Years of maternal education
timeFrame: information collected at start of study
Other outcomes:
Locations:
city: West Lafayette
country: United States
facility: Purdue University
state: Indiana
Study officials:
affiliation: Purdue Universtiy
name: Laurence B. Leonard, PhD
role: PRINCIPAL_INVESTIGATOR
References: