Clinical trial NCT01328275: Progress Adult Study
Official title: The Thai HIV Disease Progression: An Observational Database
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: HIV
Depression
Keywords: HIV related adverse events
immunological failure
virological failure
quality of life
depression
genotypic resistance
Lead sponsor: The HIV Netherlands Australia Thailand Research Collaboration
Sponsor class: OTHER
Collaborators: name: Bamrasnaradura Infectious Diseases Institute
name: Sanpatong Hospital
First posted: 2011-04-04
Enrollment: 5600
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: HIV-infected patients currently receiving ART at Bamrasnaradura Institute, Sanpatong Hospital or HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok.

Brief summary: The purpose of this study is to study the HIV disease progression in HIV-infected Thai Adult.

Detailed description: This is a multicenter, observational prospective cohort study. All HIV-infected patients from Bamrasnaradura Institute, Sanpatong Hospital and HIV-NAT, Thai Red Cross AIDS Research Centre, are followed to assess HIV disease progression.

Eligibility criteria: Inclusion Criteria:

1. There is evidence that HIV infection true (blood positive results by ELISA (ELISA) has been confirmed or detected evidence co-infection. HIV in the body by PCR, HIV-RNA PCR).Currently on PI regimens
2. Signed consent form
3. Age\> 18 years

Exclusion Criteria:

1. Patients who came for treatment in a department other than out patient, such as inpatient or emergency room.
2. Patients are not willing to receive treatment on a regular basis in all 3 hospitals as patients normally receive treatment at other hospitals on a regular basis. However, due to urgent events. Need to receive treatment in hospital and three of.
3. Patients who have been diagnosed by doctors as a Psychological disorder that can not store the data.
4. Patients who have been diagnosed by a medical condition that Alcoholism

Primary outcomes:
measure: HIV related adverse events
timeFrame: 1 year
Secondary outcomes:
measure: Immunological failure
timeFrame: 1 year
measure: virological failure
timeFrame: 1 year
measure: the change of quality of life
timeFrame: 1 year
measure: depression
timeFrame: 1 year
measure: genotypic resistance
timeFrame: 1 year
Other outcomes:
Locations:
city: Bangkok
country: Thailand
facility: HIV-NAT, Thai Red Cross AIDS Research Centre
city: Chiang Mai
country: Thailand
facility: Sanpatong Hospital
city: Nonthaburi
country: Thailand
facility: Bamrasnaradura infectious disease institute
Study officials:
affiliation: Bamrasnaradura infectious disease institute
name: Wisit Prasithsirikul, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Sanpatong Hospital
name: Wirat Klinbuayam, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: HIV-NAT, Thai Red Cross - AIDS Research Centre
name: Jintanat Ananworanich, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Pongpirul W, Pongpirul K, Ananworanich J, Klinbuayaem V, Avihingsanon A, Prasithsirikul W. Chronic kidney disease incidence and survival of Thai HIV-infected patients. AIDS. 2018 Jan 28;32(3):393-398. doi: 10.1097/QAD.0000000000001698.