Clinical trial NCT05259670: Risk Factors for Recurrent Intussusception Successful Reduction in Pediatric Patients
Official title: Risk Factors for Recurrent Intussusception After Successful Reduction in Pediatric Patients in a Tertiary Care Hospital of Nepal: A Prospective-Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Intussusception
Keywords: Hydrostatic reduction
Recurrence
Pediatrics
Lead sponsor: Nepal Medical Student Society
Sponsor class: OTHER
Collaborators: name: Tribhuvan University Teaching Hospital, Institute Of Medicine.
First posted: 2022-02-28
Enrollment: 78
Sex: ALL
Minimum age (years): 0
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Pediatric population age less than 16 years old recruited undergoing recurrent intussusception with successful reduction followed up for 1 month.

Brief summary: To determine risk factors associated with recurrent intussusception among pediatric patients who have undergone successful reduction at a tertiary care hospital.

Detailed description: This is the prospective observational study. In this study, 78 patients,age \<16 years with diagnosis of intussusception between June 2019 and April 2020 who had successful reduction with either hydrostatic reduction and/or operative reduction in Teaching Hospital were enrolled in the study. They were followed up to a period of 1 month for recurrence of intussusception. The recurrent cases were thus identified and various variables were compared between recurrent and non-recurrent cases by univariable and multivariable analysis.

This prospective observational study was approved by the ethics committees of Institutional review board of Tribhuvan University, Institute of Medicine.

A standard structured questionnaire was filled by interviewing the patient (if possible) and family members/relatives after taking informed written consent. The questionnaire documented the patient's age, sex, weight, duration of symptoms, presenting symptoms: abdominal pain, excessive cry, vomiting, lethargy, blood in stool, fever, palpable mass, constipation, diarrhoea ,location of mass, enlarged lymph nodes(LNs), blood counts and methods of reduction. Age of 2 years, weight of 12 kg and duration of symptoms of 48 hours was used to classify patients into two groups

Eligibility criteria: Inclusion Criteria:

* We included the patients who were diagnosed with intussusception from the age of 0 year to 16 years who received nonoperative and operative reduction as an initial treatment.

Exclusion Criteria:

* Pediatric patients with spontaneous reduction of hydro-reduction and who required resection and anastomosis as a part of operative procedure were excluded from the study.

Primary outcomes:
measure: Risk factor for recurrent intussusception
timeFrame: June 2019-April 2020
Secondary outcomes:
Other outcomes:
Locations:
city: Kathmandu
country: Nepal
facility: Tribhuvan University Teaching hospital
state: Bagmati
city: Maharajgunj
country: Nepal
facility: Tribhuvan University Teaching hospital
state: Bagmati
Study officials:
References: