Clinical trial NCT04791241: A Check-list Including Lung Ultrasound for ED Patients With ARF
Official title: Evaluation of a Check-list Including Lung Ultrasound for the Management of Patients With Acute Respiratory Failure at the Emergency Department During the COVID-19 Era
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Acute Respiratory Failure
Keywords: Covid19
Acute Respiratory Failure
Ultrasound
Checklist
Emergency
Diagnosis
Lead sponsor: Centre Hospitalier Metropole Savoie
Sponsor class: OTHER
First posted: 2021-03-10
Enrollment: 105
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: The aim of the study is to evaluate if a check-list including lung ultrasonography can help to identify the etiology of the acute respiratory failure of patients managed at the emergency room.

Adult patients admitted to the emergency room for acute respiratory failure will be offered the study. The emergency physician will perform a systematic examination using a checklist, including pulmonary embolism prediction scores, structured clinical examination and lung ultrasound, in order to establish a diagnostic hypothesis.

A diagnostic hypothesis will be made after completion of the checklist. The emergency physician can perform additional examinations and treatment after completion of the checklist.

The final diagnosis will be checked by an adjudication committee which will have all the documents established during the emergency room consultation and any hospitalization following this hospitalization.

The main outcome will be the concordance rate between the diagnosis after the check-list and the final diagnosis.


Eligibility criteria: Inclusion Criteria:

* Patient with acute respiratory failure table (SpO2 90% in ambient air or need more than 3 L/min of oxygen to have SpO2 \> 92% AND/OR signs of respiratory struggle sign AND/OR respiratory rate control \> 25 cycles/minute AND/OR cyanosis)
* Over 18 years old

Exclusion Criteria:

* Pregnant, Parturising or Breastfeeding Women
* Patient who has already participated in the study in the previous 7 days

Primary outcomes:
measure: Agreement between the etiology retained after using the checklist and the diagnosis retained by an adjudication committee after analysis of the entire patient file.
timeFrame: 1 month after inclusion
Secondary outcomes:
measure: Analysis of the diagnosis retained after the checklist in patients with a final diagnosis of COVID-19; analysis of the final diagnosis in patients with a diagnosis of COVID-19 evoked after the checklist
timeFrame: One month after inclusion
measure: Collection of treatments started only after completion of the checklist and verification of its suitability for the diagnosis selected
timeFrame: at one day
measure: Collection of additional examinations possibly performed in the emergency unit after the completion of the checklist
timeFrame: at one day
measure: Comparison of treatments introduced after completion of the checklist and after the other additional examinations performed at the emergency room
timeFrame: at one day
measure: Delay between completion of the checklist and obtaining the results of any other examinations
timeFrame: At one day
Other outcomes:
Locations:
city: Annecy
country: France
facility: CH Annecy Genevois
city: Chambéry
country: France
facility: Centre Hospitalier Metropole Savoie
city: Grenoble
country: France
facility: CHUGA
Study officials:
References: