Clinical trial NCT04722016: LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE
Official title: LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Newborn Rds
Transient Tachypnea of the Newborn
Pneumonia
Keywords: lung ultrasonography
chest x ray
newborn
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2021-01-25
Enrollment: 104
Sex: ALL
Maximum age (years): 2
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Term or preterm neonates with respiratory distress that started within the first 24 h after birth

Brief summary: We aimed to decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography.

From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study. We used bed side ultrasound as the first line tecnique for lung imaging. X-ray were taken in cases with increasing respiratory distress in spite of treatment according to diagnosis depending on USG findings. We calculated decreased number of chest X-ray for every patient and evaluated the estimated decrease in radiation exposure.

Detailed description: Background:

Chest X-ray is commonly used as first line imaging method to diagnose the reason of respiratory distress in NICUs. Lung ultrasound is a new diagnostic tool for lung imaging, and this method has been used more common recently in NICUs.

Objectives:

We aimed to determine the decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography.

Methods:

From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study. We used bed side ultrasound as the first line tecnique for lung imaging. X-ray were taken in cases with increasing respiratory distress in spite of treatment according to diagnosis depending on USG findings. We calculated decreased number of chest X-ray for every patient and evaluated the estimated decrease in radiation exposure.

Eligibility criteria: Inclusion Criteria:

* Term or preterm neonates with respiratory distress that started within the first 24 h after birth were included if they showed at admission signs of respiratory distress defined as: tachypnea (respiratory rate \>60 breaths/min), intercostal/subcostal retractions, grunting, or FiO2 requirement \>0.21.

Exclusion Criteria:

* Patients with a diagnosis of major malformations or chromosomal abnormalities, inherited metabolic diseases, congenital muscle disease-hypotonicity, hypoxic ischemic encephalopathy were not enrolled.

Primary outcomes:
measure: Reduced radiation exposure
timeFrame: 18 months
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
Study officials:
References:
citation: Escourrou G, De Luca D. Lung ultrasound decreased radiation exposure in preterm infants in a neonatal intensive care unit. Acta Paediatr. 2016 May;105(5):e237-9. doi: 10.1111/apa.13369. No abstract available.
citation: Tandircioglu UA, Yigit S, Oguz B, Kayki G, Celik HT, Yurdakok M. Lung ultrasonography decreases radiation exposure in newborns with respiratory distress: a retrospective cohort study. Eur J Pediatr. 2022 Mar;181(3):1029-1035. doi: 10.1007/s00431-021-04296-5. Epub 2021 Oct 23.