Clinical trial NCT06133400: Mapping the Health Status of the Population of French Polynesia: the MATAEA Project
Official title: Mapping the Health Status of the Population of French Polynesia: the MATAEA Project
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Non Communicable Diseases
Microbiome
Communicable Diseases
Pesticide Exposure
Metal Poison
Genetics Population
Ciguatera
Keywords: cross-sectional survey
non-communicable disease
communicable disease
French Polynesia
population genetics
Lead sponsor: Institut Louis Malardé
Sponsor class: OTHER
Collaborators: name: Institut Pasteur
name: Institut de la Statistique de la Polynésie française
name: Centre Hospitalier de la Polynésie française
name: Université de la Polynésie française
name: Institut National en Santé Publique du Québec
First posted: 2023-11-15
Enrollment: 1942
Sex: ALL
Minimum age (years): 18
Maximum age (years): 69
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: This is a cross-sectional study carried out on a sample of the adult population aged 18 to 69, distributed over the five archipelagos of French Polynesia.

Participation in the study involves: agreement to answer a questionnaire to collect information on socio-demographic characteristics, lifestyle habits and medical history; physical measurements (height, weight, waist circumference, blood pressure and skin pigmentation); and agreement to take biological samples (blood, saliva and stool) for biological, genetic and microbiological analyses.

The aim of the study is to assess the current health status of the population of French Polynesia and to evaluate the influence of contextual risk factors (lifestyle, place of residence, history of infection) and intrinsic susceptibility factors (genetics, age, gender, microbiota) in relation to non-communicable and infectious diseases.


Eligibility criteria: Inclusion Criteria:

* be aged 18 or over and under 70 on the date of recruitment
* having signed the consent form

Exclusion Criteria:

* Minors
* Pregnant or parturient women, and nursing mothers
* Persons deprived of their liberty by a judicial or administrative decision
* Adults who are the subject of a legal protection measure or who are unable to express their consent
* People undergoing psychiatric care
* Individuals who are not affiliated to a social security scheme or beneficiaries of such a scheme
* Homeless people
* Disabled people (unable to move)
* People unable to answer the questionnaire

Primary outcomes:
measure: Prevalence of obesity
timeFrame: 2 years
measure: Prevalence of diabetes
timeFrame: 2 years
measure: Prevalence of cardiovascular diseases
timeFrame: 2 years
measure: Association between non-communicable diseases and behavioral factors
timeFrame: 2 years
measure: Association between non-communicable diseases and physical measurements
timeFrame: 2 years
measure: Association between non-communicable diseases and blood analyses
timeFrame: 2 years
measure: Seroprevalence of communicable diseases
timeFrame: 2 years
measure: Composition of microbiome
timeFrame: 2 years
measure: Level of exposure to heavy metals
timeFrame: 2 years
measure: Level of exposure to pesticides
timeFrame: 2 years
measure: Level of exposure to mosquito bites
timeFrame: 2 years
measure: Prevalence of ciguatera poisoning
timeFrame: 2 years
measure: Demographic and adaptive history of French Polynesians using genomics
timeFrame: 2 years
measure: Genetic susceptibility to obesity
timeFrame: 2 years
measure: Genetic susceptibility to diabetes
timeFrame: 2 years
measure: Genetic susceptibility to communicable diseases
timeFrame: 2 years
Secondary outcomes:
Other outcomes:
Locations:
city: Papeete
country: French Polynesia
facility: Institut Louis Malardé
state: Tahiti
Study officials:
affiliation: Institut Louis Malardé
name: Van-Mai CAO-LORMEAU, PhD
role: STUDY_DIRECTOR
References: