Clinical trial NCT05777200: Sociodemographic and Clinical Characteristics of Patients Admitted to the Addiction Management Unit
Official title: Sociodemographic and Clinical Characteristics of Patients Admitted to the Addiction Management Unit of Assiut University Hospital
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Substance Use Disorders
Keywords: substance use disorder
addiction
Sociodemographic characteristics
personality traits
patterns of substance abuse
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2023-03-21
Enrollment: 200
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with substance use disorder, based on DSM-5 criteria, who are admitted to the addiction management unit of Assiut University Hospital.

Brief summary: Substance use disorder (SUD) is a dynamic process that changes constantly over time with new trends of drug dependence emerge every now and then, thus timely information about trends in psychoactive substance use could yield tailored interventions and reduce potential harms.

Identifying personal, social, and demographic characteristics of patients with this disorder at the local, regional, and national levels helps physicians, health authorities, and policy-makers detect early emerging trends and enable them better plan and implement prevention, treatment, and rehabilitation programs.

This study aims to identify sociodemographic, personal characteristics, as well as patterns of illicit drug abuse in patients admitted for addiction treatment.

Detailed description: Substance use disorder (SUD) is a complex condition in which there is uncontrolled use of a substance despite its harmful consequences. People with SUD have an intense focus on using a certain substance(s) such as alcohol, tobacco, or illicit drugs, to the point where the person's ability to function in day-to-day life becomes impaired. People keep using the substance even when they know it is causing or will cause problems.

Drug use brings with it the likelihood of several negative health consequences. These can include a wide range of physical and mental health disorders, foremost of which are dependence, HIV infection, hepatitis-related liver diseases, overdose and premature death.

The problem of substance use is becoming one of the most serious and rapidly growing phenomena all over the world. It accounts for substantial global morbidity, mortality, and financial and social burden. According to Global Burden of Disease (GBD) study, there were an estimated 494,000 drug-related deaths attributable to the use of drugs in 2019.

In 2020, 1 in every 18 people aged 15-64 worldwide - an estimated 284 million people (5.6 per cent of the population) - had used a drug in the past 12 months. However, the coverage of interventions for the treatment of drug use disorders remains low overall. Implementation of scientific evidence-based drug prevention interventions remains low as well, especially in middle- and low-income countries.

In Egypt, SUD is a serious public health threat. Recent studies have demonstrated increases in the prevalence of the use of tobacco, illegal drugs, and over-the-counter drugs, particularly among youth.

Drug treatment registers are often used as a proxy indicator of treatment demand. This information is useful for analysis of service utilization and can be used as an indicator of trends in prevalence and patterns of high-risk drug consumption.

Assiut University Hospital is the biggest hospital in Upper Egypt, and it provides health services for Assiut city and most of the neighboring governorates. Addiction management unit of Assiut University Hospital contains 16 beds, based on paid service and about 400 patients have been admitted per year.

SUD is a dynamic process that changes constantly over time with new trends of drug dependence emerge every now and then, thus timely information about trends in psychoactive substance use could yield tailored interventions and reduce potential harms.

Identifying personal, social, and demographic characteristics of patients with this disorder at the local, regional, and national levels helps physicians, health authorities, and policy-makers detect early emerging trends and enable them better plan and implement prevention, treatment, and rehabilitation programs.

This study aims to identify sociodemographic, personal characteristics, as well as patterns of illicit drug abuse in patients admitted for addiction treatment.

Eligibility criteria: Inclusion Criteria:

* All patients with substance use disorder who are admitted to the addiction treatment unit.
* Accept participating into the study.

Exclusion Criteria:

* Patients refuse participating in the study.

Primary outcomes:
measure: To identify the sociodemographic characteristics of patients with substance use disorder attending addiction treatment unit.
timeFrame: One week
measure: To identify personality traits of patients with substance use disorder attending addiction treatment unit.
timeFrame: One week
measure: To identify patterns of substance abuse among patients with substance use disorder attending addiction treatment unit.
timeFrame: One week
Secondary outcomes:
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Assiut University Hospital
state: Assiut Governorate
Study officials:
affiliation: Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University
name: Alaa El Din M. Darweesh, Prof.
role: STUDY_CHAIR
affiliation: Department of Neurology and Psychiatry, Faculty of Medicine, Assiut University
name: Romany H. Gabra, Dr
role: STUDY_DIRECTOR
References:
citation: Loffredo CA, Boulos DN, Saleh DA, Jillson IA, Garas M, Loza N, Samuel P, Shaker YE, Ostrowski MJ, Amr S. Substance use by Egyptian youth: current patterns and potential avenues for prevention. Subst Use Misuse. 2015 Apr;50(5):609-18. doi: 10.3109/10826084.2014.997391. Epub 2015 Jan 28.
citation: Connery HS, McHugh RK, Reilly M, Shin S, Greenfield SF. Substance Use Disorders in Global Mental Health Delivery: Epidemiology, Treatment Gap, and Implementation of Evidence-Based Treatments. Harv Rev Psychiatry. 2020 Sep/Oct;28(5):316-327. doi: 10.1097/HRP.0000000000000271.
citation: Darweesh, A. E., Agban, M., Mohammed, M. H., & Gabra, R. H. (2020). Association between opioid use disorder (tramadol) and serum level of interleukin-2. Middle East Current Psychiatry, 27(1). https://doi.org/10.1186/s43045-020-00037-w
citation: Rabie, M., Shaker, N.M., Gaber, E. et al. Prevalence updates of substance use among Egyptian adolescents. Middle East Curr Psychiatry 27, 4 (2020). https://doi.org/10.1186/s43045-019-0013-8