Clinical trial NCT02918565: Mechanisms for Alcohol Treatment Change [MATCH] Study
Official title: Mechanisms for Alcohol Treatment Change [MATCH] Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Alcohol Consumption
Lead sponsor: University of Pittsburgh
Sponsor class: OTHER
Collaborators: name: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
First posted: 2016-09-29
Enrollment: 1131
Sex: ALL
Minimum age (years): 18
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: A 5-arm randomized trial to determine what components of a text message intervention are necessary to reduce hazardous drinking among young adults and mechanisms through which these changes occur.

Detailed description: Young adults ages 18-25 have high rates of hazardous alcohol use and alcohol-related consequences. The Emergency Department (ED) provides an important opportunity to identify young adult hazardous drinkers who could benefit from interventions. A Text Message (TM) intervention was shown to reduce alcohol consumption among young adult ED patients, showing durable effects over 9-months. The TM intervention uses behavior change techniques with the largest effect sizes in an alcohol intervention meta-analysis: "goal commitment" and "self-monitoring", along with real-time "feedback". However, the unique effect of these ingredients, and mechanisms (processes occurring within the individual) through which they operate to reduce drinking remain unclear, a critical gap addressed by this project. Young adult ED patients (ages 18-25) who screen positive for hazardous drinking will be recruited to participate in a randomized trial to determine how best to help individuals reduce hazardous drinking. All participants will be asked to complete web-based surveys at baseline, 12 and 24 weeks after enrollment, complete brief psychomotor tasks weekly for 14 weeks, and respond to text messages each Thursday and Sunday for the next 12 weeks. Those randomized to the TM interventions will additionally receive feedback on their text reports. The four TM intervention arms are: (1) Drinking Cognition Feedback (DCF), (2) Alcohol Risk Feedback (ARF), (3) Adaptive Goal Support (AGS) and (4) a combination of DCF, ARF, and AGS=COMBO). Study results have implications for designing efficient mobile interventions, and developing a dynamic theory of behavior change.

Eligibility criteria: Inclusion Criteria:

* total score of \>2 for women or \>3 for men on the AUDIT-C
* at least 1 binged drinking episode in the prior 30 days

Exclusion Criteria:

* no cell phone with text messaging
* have been diagnosed with an alcohol or substance use disorder
* pregnant or planning pregnancy
* taking medicine for a psychiatric disorder (including depression, anxiety)
* taking any medicine that could interact with alcohol

Primary outcomes:
measure: Number of Binge Drinking Days
timeFrame: 12 weeks after starting intervention
Secondary outcomes:
measure: Drinks Per Drinking Day
timeFrame: 12 weeks after starting intervention
measure: Count of Participants With Any Binge Drinking Day
timeFrame: 12 weeks after starting intervention
measure: Brief Young Adult Alcohol Consequences Questionnaire Score
timeFrame: 12 weeks after starting intervention
Other outcomes:
Locations:
city: Pittsburgh
country: United States
facility: University of Pittsburgh Medical Center Emergency Department
state: Pennsylvania
Study officials:
affiliation: University of Pittsburgh
name: Brian Suffoletto, MD MS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Suffoletto B, Field M, Chung T. Attentional and approach biases to alcohol cues among young adult drinkers: An ecological momentary assessment study. Exp Clin Psychopharmacol. 2020 Dec;28(6):649-658. doi: 10.1037/pha0000343. Epub 2019 Dec 30.