Clinical trial NCT03153631: Female Sexual Dysfunction in Breast Cancer Patients
Official title: Evaluating Female Sexual Dysfunction in Breast Cancer Patients After Mastectomy
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Female Breast Cancer
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2017-05-15
Enrollment: 75
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Seventy five female, with cancer breast who did mastectomy at child bearing period, will be recruited from the outpatient clinic of clinical oncology department in Assiut University hospital and South Egypt Cancer Institute.

Brief summary: Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death among females world wide. breast cancer alone accounts for 25% of all cancer cases and 15% of all cancer deaths among females.

Detailed description: In Egypt, cancer breast is one of the commonest cancers among females representing 38.8%.cancer breast among females ranked the top with a high frequency in lower, middle, upper Egypt (33.8%,26.8%,38.7% resp.).

Women who developed breast cancer were more amenable than women who remained free of breast carcinoma to experience reduced physical function, vitality, social function.

Difficulties related to sexuality and sexual functioning were common and occurred soon after surgical and adjuvant treatment. addressing these problems is essential to improve the quality of life of young women with breast cancer.

Sexuality is a basic and important domain of human experience that can be damaged during and following cancer treatment. The risk of sexual dysfunction is even of greater importance among young cancer patients and survivors, with young breast cancer patients at particularly high risk.

In cancer breast patients, various factors can induce sexual dysfunction. Some of these factors; hormonal alterations induced by chemotherapy and radiotherapy, or physiological and functional disturbances are related to the deterioration of physical condition. These factors are strictly clinical.

Other factors which induce disturbances in sexual behavior, such as anxious\\ depressive reactions in adapting to illness and treatment and cancerophobic reactions and loss of self esteem that accompany any illness are more psychological\\ psychiatric in nature.

Having sexual problems (or dysfunction) includes experiencing disturbances in sexual desire and physiological changes associated with loss of sexual desire and arousal, reduction in sexual pleasure, difficulty achieving orgasm, anxiety about sexual performance and pain during intercourse.

Eligibility criteria: Inclusion Criteria:

* Age: 18-40 years old.
* Social status: Married.
* (Performance status): Who 0-1

  * 0-Asymptomatic (fully active, able to carry on all predisease activities without restriction)
  * 1-Symptomatic but completely ambulatory (restricted in physically strenuous activity but ambulatory and able to carry out work of light or sedentary nature. For example, light housework, office work)

Exclusion Criteria:

* Pregnant women.
* Comorbidities (Diabetes mellitus., Hypertension).
* Female genital tract disease.

Primary outcomes:
measure: assessment of female sexual dysfunction in breast cancer patients after mastectomy using questionaire
timeFrame: one month
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
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