Clinical trial NCT01512641: Prevalence of Dissociative Disorders in Children
Official title: Prevalence of Dissociative Disorders in Children in a Population Supported in the Medico-social and Health Structures in Provence Alpes Cote d'Azur
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dissociative Disorders
Schizophrenia
Keywords: children dissociative disorders schizophrenia
Lead sponsor: Centre Hospitalier Universitaire de Nice
Sponsor class: OTHER
First posted: 2012-01-19
Enrollment: 301
Sex: ALL
Minimum age (years): 7
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: Schizophrenia beginning before 18 years is a clinical entity not well known because of its low incidence and difficulties in the clinical diagnosis.

However, in the investigators clinical practice, due to the specialization of the investigators service, the investigators are led to hospital to receive important feel active of patients meeting the Diagnostic and Statistical Manual of Mental Disorders IV text revision (DSM IV-TR) precose schizophrenia.

The work of us team on the theme of the relationship between Pervasive Developmental Disorders and precose Schizophrenia led us to hypothesize that a number of children in care in the medical and educational institutes, hospitals and day shelters therapeutic part-time symptoms of schizophrenia or a line real early diagnosis of schizophrenia undervalued or not diagnosed.

The main goal is to estimate the prevalence of dissociative disorders in a population of children in care institutions and medical education in child psychiatry in hospitals and others structures.


Eligibility criteria: Inclusion Criteria:

* 7 to 18 years
* Supported in the partner institutions of the study
* IQ\>35 on the certificate of orientation of the Maison Départementale des Personnes Handicapées (MDPH)
* Obtaining the agreement of parents and children

Exclusion Criteria:

* QI\<35 on the certificate file Guidance MDPH
* Children not speaking french

Primary outcomes:
measure: Rate of children diagnosed with dissociative disorders
timeFrame: between 2 and 4 hours depending children
Secondary outcomes:
measure: Percentage of children positive for test: Autism Diagnostic Interview-Revise (ADI-R).
timeFrame: 1 day on average
measure: Scores of three dimensions of schizophrenia in the Positive And Negative Syndrome Scale (PANSS)
timeFrame: 4 hours
measure: Score at the Test Lillois de Communication (TLC)
timeFrame: 30 minutes
measure: Score on the Wechsler Intelligence Scale for Children-Fourth Edition (WISC IV)subtests and overall intelligence quotient (IQ).
timeFrame: 4 hours
measure: Response time to test verbal fluency, scores on the Trail Making Test A (TMT) and TMT B.
timeFrame: 30 minutes
Other outcomes:
Locations:
city: Antibes
country: France
facility: Psychiatrie infanto-juvénile - Centre Hospitalier d'Antibes
city: Fréjus
country: France
facility: Psychiatrie infanto-juvénile-Pôle femme-mère -enfant
city: Marseille
country: France
facility: Service de psychiatrie de l'enfant et de l'adolescent
city: Nice
country: France
facility: Service de psychiatrie de l'enfant et de l'adolescent
Study officials:
affiliation: University hospital of Nice
name: Florence ASKENAZY, PU-PH
role: STUDY_DIRECTOR
affiliation: University hospital of Nice
name: Emmanuelle DOR, PH
role: PRINCIPAL_INVESTIGATOR
affiliation: AP-HM
name: François POINSO, PU-PH
role: PRINCIPAL_INVESTIGATOR
affiliation: Frejus's hospital
name: Michèle BATTISTA, PH
role: PRINCIPAL_INVESTIGATOR
affiliation: Antibes's hospital
name: Michel BOUBLIL, PH
role: PRINCIPAL_INVESTIGATOR
References:
citation: Dor-Nedonsel E, Menard ML, Fernandez A, Sakarovitch C, Fontas E, Salle-Collemiche X, Poinso F, Tosello AL, Maria F, Manera V, Askenazy F, Thummler S. Early-Onset Schizophrenia in a paediatric population of French psychiatric and medico-social care centres: A cross sectional study. PLoS One. 2020 Jul 27;15(7):e0236241. doi: 10.1371/journal.pone.0236241. eCollection 2020.