Clinical trial NCT04926363: Prevalence of Cardiovascular Risk Factors in Upper Vestibular Neuritis
Official title: Prevalence of Cardiovascular Risk Factors in People With Upper Vestibular Neuritis
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Vestibular Neuritis
Keywords: Vestibular neuritis
Anterior vestibular artery
Lead sponsor: University Hospital, Strasbourg, France
Sponsor class: OTHER
First posted: 2021-06-15
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Major having presented an episode of upper vestibular neuritis recorded on the Video Head Impulse Test Ulmer device at the HUS between 01/01/2016 and 01/31/2020,

Brief summary: Vestibular neuritis is the second cause of vertigo, it constitutes 5 to 6% of the aetiologies of vertigo in an otoneurological consultation.

Infection or reactivation of a neurotropic virus of the herpes group (HSV-1) in the vestibular lymph node is thought to be the cause of the unilateral vestibular deficit.

Upper vestibular neuritis is more common than lower, or total involvement. Goebel (2) explains this by an anatomical predisposition of the vestibular nerve canal to inflammation, unlike the singular nerve canal which is shorter and wider giving way to a certain degree of edema without consequence on its contents.

However, the innervation territory of the superior vestibular nerve is superimposable on the territory supplied by the anterior vestibular artery. The anterior, lateral semicircular canals and the utricle are affected. Current complementary vestibular and imaging examinations cannot differentiate between inflammatory or vascular involvement in upper vestibular neuritis.

The increased presence of cardiovascular risk factors in patients with upper vestibular neuritis would be an argument in favor of ischemic involvement of the anterior vestibular artery.


Eligibility criteria: nclusion criteria:

* Major subject (≥18 years old),
* Subject having presented an episode of upper vestibular neuritis recorded on the Video Head Impulse Test Ulmer device at the HUS between 01/01/2016 and 01/31/2020,
* Subject not having expressed his opposition, after information, to the reuse of his data for the purposes of this research.

Exclusion criteria:

* Patient who expressed his opposition to participating in the study,
* Total vestibular neuritis,
* impossibility of providing the subject with enlightened information (difficulties in understanding the subject, etc.)
* Subject under safeguard of justice,
* Subject under guardianship or guardianship,
* Lack of video head impulse test data.

Primary outcomes:
measure: Retrospective study of cardiovascular risk factors in people with upper vestibular neuritis
timeFrame: Files analysed retrospectively from January 01, 2016 to January 31, 2020 will be examined]
Secondary outcomes:
Other outcomes:
Locations:
city: Strasbourg
country: France
facility: Service ORL et de CCF - Hôpitaux Universitaires de Strasbourg
Study officials:
affiliation: Service ORL et de CCF- Hôpitaux Universitaires de Strasbourg
name: Anne CHARPIOT, MD, PhD
role: STUDY_DIRECTOR
References: