Clinical trial NCT06479486: Clinimetric Properties of Performance-based Measures of Physical Function in Patients With COPD
Official title: Clinimetric Properties of Performance-based Measures of Physical Function in Patients With COPD: a Comparison of Clinimetric Properties of Four Tools
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: Clinimetric properties, COPD, performance-based measures
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-06-28
Enrollment: 50
Sex: ALL
Minimum age (years): 40
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Single Group Assignment
Primary purpose: TREATMENT

Brief summary: A COPD (Chronic obstructive pulmonary disease), is a group of progressive lung diseases. COPD is a preventable and treatable respiratory disorder largely caused by smoking and long term exposure to chemical irritants. This study aims to provide essential insights into the reliability, validity, responsiveness and Interpretability of such tests, enabling healthcare professionals to make informed decisions about patient recovery progress and the optimization of rehabilitation protocols.

Detailed description: A COPD (Chronic obstructive pulmonary disease), is a group of progressive lung diseases, a preventable and treatable respiratory disorder largely caused by smoking and long term exposure to chemical irritants. COPD affects the respiratory system and is progressive, which can result in a number of difficulties or impairments. ) Effect on Daily Activities, Work Limitations, Fatigue Muscle Weakness, Breathlessness and Reduced Exercise Capacity, and Impaired Quality of Life. Pulmonary rehabilitation is a comprehensive course that helps people with chronic respiratory illnesses, such as COPD, improve their overall health and quality of life. Clinimetric properties of four distinct tools designed for assessing performance-based physical functional outcomes following COPD patients surgery. 6 Minute Walk Test (6MWT), 2 minute Walk test (2MWT), and Timed Up and GO (TUG), 30sec sit to stand test (30sec STS) will be assessed to determine any changes in their functionality test.

Eligibility criteria: Inclusion Criteria:

* Diagnosed cases of COPD (FEV1/FVC \< 0.70).
* Both genders
* Clinically stable
* Age 40-65 years

Exclusion Criteria:

* Disease exacerbation in last 4 weeks
* Co-existing respiratory or any other condition
* Inability to perform tests due to cognitive or any physical limitations

Primary outcomes:
measure: 6MWT (Six-Minute Walk Test)
timeFrame: 6 week
measure: 2MWT (Two-Minute Walk Test)
timeFrame: 6 week
measure: Timed Up and GO (TUG)
timeFrame: 6 week
measure: 30 seconds sit to stand test (30SSTS):
timeFrame: 6 week
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Hearts International Hospital
state: AL
Study officials:
affiliation: Riphah International University
name: Suman Sheraz, PhD*
role: PRINCIPAL_INVESTIGATOR
References:
citation: Massierer D, Alsowayan W, Lima VP, Bourbeau J, Janaudis-Ferreira T. Prognostic value of simple measures of physical function and muscle strength in COPD: A systematic review. Respir Med. 2020 Jan;161:105856. doi: 10.1016/j.rmed.2019.105856. Epub 2019 Dec 19.
citation: Charlson ME, Carrozzino D, Guidi J, Patierno C. Charlson Comorbidity Index: A Critical Review of Clinimetric Properties. Psychother Psychosom. 2022;91(1):8-35. doi: 10.1159/000521288. Epub 2022 Jan 6.