Clinical trial NCT03762239: Effect of Air Pollution on the Cognitive Function of Adolescents
Official title: Citizen Science for Analysing the Effect of Air Pollution on the Cognitive Function of Adolescents
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Attention Impaired
Risk-Taking
Risk Behavior
Social Preferences
Decision Making
Attention
Keywords: Attention
Air pollution
Black carbon
Particulate matter
Risk behavior
Social preferences
Decision making
Air purifier
Air cleaner
Lead sponsor: Barcelona Institute for Global Health
Sponsor class: OTHER
Collaborators: name: Recercaixa
name: Centre de Recerca per a l'Educació Científica i Matemàtica (CRECIM)
name: Institute of Environmental Assessment and Water Research (IDAEA-CSIC)
name: Economics and Bussiness Department, Universtitat Pompeu Fabra
First posted: 2018-12-03
Enrollment: 2123
Sex: ALL
Minimum age (years): 13
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Previous observational studies have reported an association between higher air pollution exposure and lower attention in children. With this project, the investigators aim to confirm this association in adolescents using an experimental design. In addition, the study will assess the relationship between air pollution exposure and individual preferences with respect to risk, time and social considerations. High school students in 3rd grade (ESO, 14-15 years of age) in different high schools in the Barcelona province (Spain) will be invited to participate. For each class in each high school, participating students will be randomly split into two equal-sized groups. Each group will be assigned to a different classroom where they will complete several activities during two hours, including an attention test (Flanker task) and a reduced version of the Global Preferences Survey. One of the classrooms will have an air purifier that will clean the air. The other classroom will have the same device but without the filters, so it will only re-circulate the air without cleaning it. Students will be masked to intervention allocation. The investigators hypothesize that students assigned to the clean air classroom will have better scores in the attention test, and that decision-making will also present differences in the two classrooms.


Eligibility criteria: Inclusion Criteria:

* Students in the 3rd ESO course in participating high schools with signed informed consent

Exclusion Criteria:

* None

Primary outcomes:
measure: Response Speed Consistency Throughout the Attention Network Task-Flanker Task (Post ANT)
timeFrame: Obtained from a test administered approximately 90 minutes after entering the classroom
measure: Combined Risk Taking Score
timeFrame: Obtained from a test administered approximately 100 minutes after entering the classroom
measure: Combined Patience Score
timeFrame: Obtained from a test administered approximately 100 minutes after entering the classroom
measure: Positive Reciprocity Score
timeFrame: Obtained from a test administered approximately 100 minutes after entering the classroom
measure: Altruism Score
timeFrame: Obtained from a test administered approximately 100 minutes after entering the classroom
measure: Trust Score
timeFrame: Obtained from a test administered approximately 100 minutes after entering the classroom
Secondary outcomes:
measure: Impulsivity (From ANT)
timeFrame: Obtained from a test administered approximately 90 minutes after entering the classroom
measure: Selective Attention (From ANT)
timeFrame: Obtained from a test administered approximately 90 minutes after entering the classroom
measure: Alerting Score (From ANT)
timeFrame: Obtained from a test administered approximately 90 minutes after entering the classroom
measure: Orienting Score (From ANT)
timeFrame: Obtained from a test administered approximately 90 minutes after entering the classroom
measure: Conflict Score (Executive Attention) (From ANT)
timeFrame: Obtained from a test administered approximately 90 minutes after entering the classroom
measure: Self Assessment of How Good They Are in Math
timeFrame: Obtained from a test administered approximately 100 minutes after entering the classroom
Other outcomes:
Locations:
city: Barcelona
country: Spain
facility: ISGlobal
Study officials:
affiliation: Barcelona Institute for Global Health
name: Xavier Basagaña, PhD
role: PRINCIPAL_INVESTIGATOR
References: