Clinical trial NCT06481865: Weight-bearing of Patients After Pelvic Ring Fracture
Official title: Weight-bearing of Patients After Pelvic Ring Fracture: A Monocentric Observational Study
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Weight-bearing of Patients After Pelvic Ring Fracture
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
First posted: 2024-07-01
Enrollment: 250
Sex: ALL
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: All patients treated in the orthopedics and traumatology department at CHU de Grenoble Alpes between 01/01/2020 and 31/12/2022 for a pelvic ring fracture are selected for the monocentric observational study.

Epidemiological data, preoperative management, fracture patterns according to classification (Tile and AO/OTA), operative data, and radiological criteria (X-rays and CT scans) are collected and analyzed retrospectively

Brief summary: Pelvic ring fractures are fractures associated with high morbidity and mortality. When the fracture is displaced, surgical management to achieve reduction and fixation of the anterior and posterior annulus is the current reference. The optimal technique that gives the best results is controversial. Open reductions and internal fixations (ORIFs) are associated with more blood loss and a higher rate of infection, while closed reductions and percutaneous fixations (CRPF) are associated with more screw misplacements and thus vascular or nerve damage. The results appear to be similar in the literature between the two approaches

Surgery for pelvic ring fractures has become increasingly common over the past three decades Recovery is often delayed for weeks post-surgery, depending on the center. Modern management emphasizes early rehabilitation, including early mobility and weight-bearing, when possible. Increasing the number of screws, their diameter and length, and systematically fixing both anterior and posterior lesions add safety for early reloading

The aim of the study is The main objective of the study is to evaluate the clinical outcome associated with early weight-bearing in patients operated on for a pelvic ring fracture in a large cohort of patients at Grenoble University Hospital, compared to patients operated on for the same type of pelvic ring fracture with delayed weight-bearing.

The investigator hypothesize that early weight-bearing of pelvic ring fractures with biomechanically stable fixation does not result in significant differences in clinical outcomes at a minimum of one year compared to patients with delayed weight-bearing


Eligibility criteria: Inclusion Criteria:

* Adult patient at the time of injury
* Pelvic ring fracture
* Pre-operative X-rays
* Pre-operative CT scan
* Post-operative X-rays
* Postoperative CT scan
* Willingness and ability to participate in the study.

Exclusion Criteria:

* Ipsi-lateral fracture of the femoral and/or associated acetabulum (Floating Hip C or B)
* Pregnant and breastfeeding women
* People under guardianship, protected adults

Primary outcomes:
measure: Evaluate the clinical outcome associated with early weight-bearing in patients operated on for a pelvic ring fracture compared to patients operated on for the same type of pelvic ring fracture with delayed weight-bearing
timeFrame: 1 year
Secondary outcomes:
measure: Define the prognostic factors associated with poor clinical outcomes and Pseudoarthrosis or vicious callus.
timeFrame: 1 year
measure: Compare clinical outcomes and radiological results with the literature
timeFrame: 1 year
measure: Compare clinical outcomes and radiological results with the literature
timeFrame: 1 year
measure: Compare clinical outcomes and radiological results with the literature
timeFrame: 1 year
measure: Evaluation of the outcomes and complications of immediate weight-bearing in elderly patients.
timeFrame: 1 year
Other outcomes:
Locations:
city: Grenoble
country: France
facility: Grenoble Alpes university Hospital,La tronche
Study officials:
affiliation: Grenoble Alpes University Hospital
name: Mehdi PI BOUDISSA
role: PRINCIPAL_INVESTIGATOR
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