Clinical trial NCT06998017: The Feasibility of LVHIIT on Inpatient Stroke Rehab
Official title: The Feasibility of Low-Volume High Intensity Interval Training on Inpatient Stroke Rehab
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: EARLY_PHASE1
Conditions: Stroke
High Intensity Interval Training
Aerobic Fitness
Physical Therapy
Lead sponsor: University of Kansas Medical Center
Sponsor class: OTHER
First posted: 2025-05-31
Enrollment: 15
Sex: ALL
Minimum age (years): 18
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: The objective of this study is to explore the safety and feasibility of conducting low-volume, high-intensity interval training (HIIT) on a total body recumbent stepper (TBRS) in persons with stroke in an inpatient rehabilitation setting.


Eligibility criteria: Inclusion Criteria:

* -Both sexes between the age of 18-85 years at time of consent
* Ischemic or hemorrhagic stroke at consent. People with stroke and newly diagnosed cardiovascular complications had \>50% prevalence of recurrent stroke at 5 years. Index stroke or recurrent stroke on same side as index stroke will be allowed.
* Exercise continuously for minimum of 30 watts for 3 minutes on the recumbent stepper to demonstrate ability to perform the exercise test or therapist confirmation/documentation of participant's ability to use the recumbent stepper.
* No aerobic exercise contraindications or other safety/physical concerns during the submaximal exercise test determined by the therapy team or inpatient physicians.
* Able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions

Exclusion Criteria:

* Implanted pacemaker or defibrillator limiting exercise performance
* Reported pain that limits or interferes with activities of daily living and physical activity/exercise
* Acute Myocardial Infarction in the last 2 days
* Ongoing unstable Angina
* Active Endocarditis
* Symptomatic Severe Aortic Stenosis
* Decompensated Heart Failure
* Acute Pulmonary Embolism, Pulmonary Insufficiency, or Deep Veinous Thrombosis
* Acute Myocarditis or Pericarditis
* Other significant neurologic, orthopedic, or peripheral vascular conditions that would limit exercise participation
* Oxygen-dependent chronic obstructive pulmonary disease
* Neurological disease (Multiple Sclerosis, Alzheimer's disease, Parkinson's disease)
* Pregnancy

Primary outcomes:
measure: Safety of LVHIIT (low volume high intensity interval training) on total body recumbent stepper
timeFrame: 2-3 months
measure: Adherence of LVHIIT (low volume high intensity interval training) on total body recumbent stepper
timeFrame: 2-3 months
measure: Attainment of LVHIIT (low volume high intensity interval training) on total body recumbent stepper
timeFrame: 2-3 months
measure: Acceptability of LVHIIT (low volume high intensity interval training) on total body recumbent stepper
timeFrame: 2-3 months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: University of Kansas
name: Alexandra Arickx, MD
role: PRINCIPAL_INVESTIGATOR
References: