louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT04031352: Investigation of Factors Affecting Children's Attitudes Towards Peers With Disability
Official title: Investigation of Factors Affecting Children's Attitudes Towards Peers With Disability
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Disability Physical
Keywords: attitude
CATCH
children
disability
peers
Lead sponsor: Pamukkale University
Sponsor class: OTHER
First posted: 2019-07-24
Enrollment: 1305
Sex: ALL
Minimum age (years): 11
Maximum age (years): 15
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 1305 elementary school students (aged 11-14 years and grades 5-8) included to the study from 6 public and 2 private schools. The students participating in the study, 48.9% (534) were female, 51.1% (558) were male.

Brief summary: Children with disabilities can be exposed to stigma and discrimination because of poor attitudes. The role of peer is crucial for development of disabled children.

The aim of the study was to investigate the attitudes of children towards their peers with disabilities and to identify factors associated with them.

1305 elementary school students included to the study. The students participating in the study, 48.9% (534) were female, 51.1% (558) were male. The Chedoke-McMaster Attitudes towards Children with Handicaps (CATCH) scale was used to investigate the children's attitudes.

Detailed description: * Being important in terms of epidemiological investigation.
* Giving new results from society with different cultural and national characteristics.
* Investigating the three components of the CATCH.

Eligibility criteria: Inclusion Criteria:

* Inclusion criteria were being a student of elementary school, being aged between 11-15 years and being volunteer.

Exclusion Criteria:

* Students who had a congenital or acquired disability or a handicap and who did not complete the scale were excluded.

Primary outcomes:
measure: CATCH
timeFrame: one year
Secondary outcomes:
Other outcomes:
Locations:
city: Denizli
country: Turkey
facility: Pamukkale University
Study officials:
affiliation: Pamukkale University
name: ALI KITIS, PROF
role: STUDY_CHAIR
affiliation: Pamukkale University
name: OZGE MINE YILMAZ, MSC
role: PRINCIPAL_INVESTIGATOR
affiliation: Pamukkale University
name: HANDE USTA, PHDc
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02341352: Three Measures for the Prevention of Carious Lesions in Preschool Children
Official title: Study on Children's Dental Caries Prevention and Mechanism
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE3
Conditions: Dental Caries
Lead sponsor: Zhejiang University
Sponsor class: OTHER
Collaborators: name: Hangzhou Occupational Disease Prevention Hospital
First posted: 2015-01-19
Enrollment: 500
Sex: ALL
Minimum age (years): 24
Maximum age (years): 54
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Analysis different measures preventive effect on carious Lesions incidence and oral microecological system change of preschool children

Detailed description: Different caries prevention trials including fluoride vanish, IgY-passive immunotherapy and probiotics lasting 24 months were conducted with a total of 500 children aged 24 to 54 months of age in Lin'an, Zhejiang, China. The trials were cluster- domized .After obtaining parent´s informed consent, preschool children were clinical examinated according to ICDAS-Ⅱ and microbiological tested of saliva at baseline, 1m, 6m, 12m, 18m and 24m. To find the differences of caries incidence and oral microecology change in four groups, dmfs will be assessed and saliva will be analysed in experiment.

Eligibility criteria: Inclusion Criteria:

* preschool children in good general health
* At least 18 deciduous teeth

Exclusion Criteria:

* With major systemic disease or on long-term medication
* Not cooperative and refuse dental treatment
* With a history of extra fluoride supplement
* Take antibiotics for nearly 8 weeks

Primary outcomes:
measure: The number of new cavitated or incipient carious lesion
timeFrame: 24 months after first visit
Secondary outcomes:
Other outcomes:
Locations:
city: Hangzhou
country: China
facility: Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University
state: Zhejiang
Study officials:
affiliation: Department of Conservative Dentistry and Periodontics, Affiliated Hospital of Stomatology, School of Medicine, Zhejiang University
name: Hui Chen
role: PRINCIPAL_INVESTIGATOR
References:
citation: Zhang J, Su L, Wang Y, Deng S. Improved High-Throughput Sequencing of the Human Oral Microbiome: From Illumina to PacBio. Can J Infect Dis Med Microbiol. 2020 Dec 11;2020:6678872. doi: 10.1155/2020/6678872. eCollection 2020.
citation: Wang Y, Wang S, Wu C, Chen X, Duan Z, Xu Q, Jiang W, Xu L, Wang T, Su L, Wang Y, Chen Y, Zhang J, Huang Y, Tong S, Zhou C, Deng S, Qin N. Oral Microbiome Alterations Associated with Early Childhood Caries Highlight the Importance of Carbohydrate Metabolic Activities. mSystems. 2019 Nov 5;4(6):e00450-19. doi: 10.1128/mSystems.00450-19.
Clinical trial NCT02069652: Prevention of Transmission of Sexually Transmitted Diseases in the Youth Through Effective Intervention,
Official title: Chung-Ho Memorial Hospital Kaohsiung Medical University
Study type: EXPANDED_ACCESS
Overall status: NO_LONGER_AVAILABLE
Conditions: HIV
Lead sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital
Sponsor class: OTHER
First posted: 2014-02-24
Sex: MALE
Minimum age (years): 15
Maximum age (years): 30
Standard ages: CHILD
ADULT

Brief summary: The data of Taiwan CDC showed the total HIV victims amounted up to 22,020 from 1984 to 2011. Under risk factor analysis, it indicated the increasing victims among MSM (men having sex with men, including homosexuals \& bisexuals) cohorts, from 64% of them in 2009 to 72% in 2011. For age stratification of patients, the youth (from 15 to 24 years old) comprised of 18.5% (4078). Among them, 40% are students. MSM are still the main population (over 80%) from 2009 to 2011. Therefore it is crucial to target the young MSM.

Detailed description: Purpose: Under the hospital based, and in conjuction with the community, we try to target the young HIV MSM victims and develop the partnership networking to seek for the potential high risk couples to enroll into our intervention.

Materials \& Methods: At hospital, though HIV clinic has case manager, however the limitation of space and privacy, we just focus on the HIV patient itself and have limited time to educate patients' sex partners. Therefore, we aimed at enrolling more of the intimate partners thru young HIV MSM victims thru hospital base. We will provide the saliva OraQuick rapid test service to the partners, thus set up the relationship with the study subjects, and then communicate with them and educate them with knowledge of sexual transmitted diseases and sex health. We plan to enroll 200 study subjects till the end of this year. Our co-PI, Prof. Y.M. Chen will also perform HIV gene clustering analysis thru high throughput ultra-deep pyrosequencing among young MSM HIV victims. The other co-PI Prof. P.I. Chou will train the research assistant adopting MSM HIV victim partner follow-up model to approach the study subjects with structured questionnaires. Prof. Chou also collected the study subjects in the northern Taiwan with her own project, thus we can compare and analyze the difference from the locality (North area v.s. South area).

Anticipated work: We aim at enrolling 300 young HIV MSM partners to this OraQuick rapid test, setting up the follow-up model and providing the intervention education of safe sex thru individual case management, group meeting, leader-finding plan and interactive MSM web networking to achieve the preventione of sexual disease transmission in the youth.

Eligibility criteria: Inclusion Criteria:

1. Homosexual or bisexual and MSM who have sex.
2. Age over 15 years old to 30 years old.

Exclusion Criteria:

1. Women and heterosexual.
2. AIDS was received within three months of screening those.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT02789852: Evaluation of the Effectiveness of Night Orthosis in Treating Women With Symptomatic Osteoarthritis in the Interphalangeal Joint of the Dominant Hand
Official title: Evaluation of the Effectiveness of Night Orthosis in Treating Women With Symptomatic Osteoarthritis in the Interphalangeal Joint of the Dominant Hand
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hand Injuries
Lead sponsor: Federal University of São Paulo
Sponsor class: OTHER
First posted: 2016-06-03
Enrollment: 52
Sex: FEMALE
Minimum age (years): 40
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Evaluation of the effectiveness of using a night orthosis for II and III or fingers of the dominant hand in women diagnosed with symptomatic osteoarthritis compared to a control group.

Detailed description: Objective: To evaluate the effectiveness of using a night orthosis for II and III or fingers of the dominant hand in women diagnosed with symptomatic osteoarthritis compared to a control group.

Methods: Through a randomized controlled clinical trial with blind assessment and follow-up of six months. Fifty-Two participants were randomized into two groups: group orthosis and control, and made a night orthosis II and or III fingers, thermoplastic will be used as a treatment for participants orthosis group. The participants underwent four evaluations at time 0, 45 days, 90 days and 180 days after its inclusion in the study. The variables studied were: the visual analog scale of pain, grip and pinch strength, questionnaires Cochin and Australian/Canadian Hand Osteoarthritis Index and functional Pick-up test.

Eligibility criteria: Inclusion Criteria:

* Women aged between 40 and 80 years.
* Patients diagnosed with osteoarthritis (OA) hand according to the American College of Rheumatology classification criteria.
* Pain symptom in proximal interphalangeal (PIP's) or distal interphalangeal (DIP's) dominant hand in II and III or fingers.
* Provide greater pain symptom of II and III or fingers between each other.
* Complains of pain symptom measured by a visual analog scale (VAS) pain between 3 to 8 cm in the II and III or fingers of the dominant hand reported to perform joint movement (activity).
* Thumb abduction with the II and III fingers without changing the pincer movement pulp-pulp.

Exclusion Criteria:

* Other rheumatic diseases, neurological and skeletal muscle that can affect the upper limb.
* Fibromyalgia uncontrolled.
* Pregnancy.
* Geographical inaccessibility and transport.
* Cognitive impairment that prevents the understanding of assessment tools.

Primary outcomes:
measure: Change in Pain
timeFrame: T0 (inclusion), T45( 45 days after inclusion), T90 (90 days after inclusion) and T180 (180 days after inclusion)
Secondary outcomes:
Other outcomes:
Locations:
city: Sao Paulo
country: Brazil
facility: Universidade Federal de Sao Paulo
state: SP
Study officials:
References:
Clinical trial NCT04452552: Ultrasound Cavitation Versus Radiofrequency on Abdominal Fat
Official title: Effect of Ultrasound Cavitation Versus Radiofrequency on Abdominal Fat Thickness in Postnatal Women
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy Diet
Keywords: Ultra-sound cavitation
Radiofrequency
fat thickness
Lead sponsor: Cairo University
Sponsor class: OTHER
Collaborators: name: Yasmin Mohamed Assim
First posted: 2020-06-30
Enrollment: 50
Minimum age (years): 25
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Fifty overweight primipara women at 6 months postnatally aged from 20-35 years, BMI (25-29.9) kg/m2 and have waist hip ratio (WHR) \> 0.8. They were assigned randomly into 2 equal groups: Group (A) received ultra-sound cavitation40 KHz applied for 30 min, once time weekly for 8 weeks. Group (B) received radiofrequency multi-polar 5MHZ applied for 30 min, once time weekly for 8 weeks. Both groups received the same diet program throughout the treatment period. All females in both groups were assessed through weight scale for body weight, tape measurement for waist/hip ratio and ultra-sonography for fat thickness of abdominal region before and after treatment
Primary purpose: TREATMENT

Brief summary: Overweight and obesity is prevalent among women of reproductive age (25-34 years) with 42% having a BMI \> 25 kg/m2. Weight gain increases the risk of developing diabetes and cardiovascular disease. The amount of weight regain postpartum can shift women from the healthy weight category into the overweight or obese BMI categories. Purpose: This study was conducted to compare the effectiveness of ultra-sound Cavitation versus radiofrequency on abdominal fat thickness on postnatal women

Detailed description: Fifty overweight primipara women at 6 months postnatally aged from 20-35 years, BMI (25-29.9) kg/m2 and have waist hip ratio (WHR) \> 0.8. They were assigned randomly into 2 equal groups: Group (A) received ultra-sound cavitation40 KHz applied for 30 min, once time weekly for 8 weeks. Group (B) received radiofrequency multi-polar 5MHZ applied for 30 min, once time weekly for 8 weeks. Both groups received the same diet program throughout the treatment period. All females in both groups were assessed through weight scale for body weight, tape measurement for waist/hip ratio and ultra-sonography for fat thickness of abdominal region before and after treatment

Eligibility criteria: Inclusion Criteria:

* Their age were ranged from 20 to 35 years
* their body mass index BMI 25-29.9 kg/m2
* their waist hip ratio (WHR) \> 0.8.

Exclusion Criteria:

* heart disease
* high cholesterol
* liver
* kidney diseases

Primary outcomes:
measure: BMI calculation
timeFrame: 8 weeks
Secondary outcomes:
measure: Waist to hip ratio Measurement
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Ghada Elrefaye
state: Cairo
Study officials:
affiliation: Cairo University
name: ghada eb elrefaye, professor
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01911052: The Impact of Telephone and Short Message System Based Education on Bowel Preparation for Colonoscopy
Official title: The Impact of Telephone and Short Message System Based Education on Bowel Preparation for Colonoscopy in Health Screened Population
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Bowel Preparation
Keywords: Bowel preparation
Lead sponsor: Keimyung University Dongsan Medical Center
Sponsor class: OTHER
First posted: 2013-07-30
Enrollment: 390
Sex: ALL
Minimum age (years): 19
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Inadequate bowel preparation results in decreased rates of cecal intubation, increased rates of missing important lesions, increased patient discomfort, higher risk of complications, prolonged procedure time and increased health-care cost. Recent study reported that Telephone-based re-education (TRE) on the day before colonoscopy significantly improved the quality of bowel preparation and polyp detection rate. However, there is no study to compare the effect of telephone with short message system (SMS) based re-education on the quality of bowel preparation in health screened population. Our goal is to improve the quality of bowel preparation with telephone or SMS based re-education for outpatients undergoing screening colonoscopies. The investigators hypothesise that efforts to improve education and maximise patient compliance during the preparatory period will enhance the efficacy of bowel preparation.


Eligibility criteria: Inclusion Criteria:

* All health screened populations
* age \>18
* scheduled for an elective screening colonoscopy

Exclusion Criteria:

* inpatients
* pregnancy
* breast feeding
* prior history of surgical large bowel resection
* patients allergic to PEG-ELS based laxatives

Primary outcomes:
measure: Quality of bowel preparation
timeFrame: day 1
Secondary outcomes:
measure: polyp detection rate
timeFrame: day 1
Other outcomes:
measure: Patient compliance
timeFrame: baseline
Locations:
city: Daegu
country: Korea, Republic of
facility: Eun Soo Kim
Study officials:
affiliation: Keimyung University School of Medicine
name: Eun Soo Kim, Professor
role: PRINCIPAL_INVESTIGATOR
References:
citation: Liu X, Luo H, Zhang L, Leung FW, Liu Z, Wang X, Huang R, Hui N, Wu K, Fan D, Pan Y, Guo X. Telephone-based re-education on the day before colonoscopy improves the quality of bowel preparation and the polyp detection rate: a prospective, colonoscopist-blinded, randomised, controlled study. Gut. 2014 Jan;63(1):125-30. doi: 10.1136/gutjnl-2012-304292. Epub 2013 Mar 16.
citation: Lee YJ, Kim ES, Choi JH, Lee KI, Park KS, Cho KB, Jang BK, Chung WJ, Hwang JS. Impact of reinforced education by telephone and short message service on the quality of bowel preparation: a randomized controlled study. Endoscopy. 2015 Nov;47(11):1018-27. doi: 10.1055/s-0034-1392406. Epub 2015 Jul 16.
Clinical trial NCT02925052: Evaluation of the Gastric Tube Guide to Place Orogastric Tubes
Official title: Evaluation of the Gastric Tube Guide to Place Orogastric Tubes: : A Prospective, Randomized Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Orogastric Tube Placement
Lead sponsor: Johannes Gutenberg University Mainz
Sponsor class: OTHER
First posted: 2016-10-05
Enrollment: 151
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A randomized controlled prospective study of orogastric tube placement with the Gastric Tube Guide vs conventional placement.


Eligibility criteria: Inclusion Criteria:

* Age ≥ 18 Years
* No concurrent participation in another study
* Capacity to consent
* Present written informed consent of the research participant
* Elective surgery in general anesthesia
* Required orogastric intubation

Exclusion Criteria:

* Existing pregnancy
* Emergency patients
* Preexisting pathological findings in the mouth, pharynx or esophagus

Primary outcomes:
measure: Success
timeFrame: 180 seconds
Secondary outcomes:
measure: Attempts
timeFrame: 180 seconds
measure: Time
timeFrame: 180 seconds
measure: Complications
timeFrame: 180 seconds
measure: Postoperative comfort
timeFrame: 24 hours
Other outcomes:
Locations:
city: Mainz
country: Germany
facility: University Medical Center
state: Rhineland-Palatinate
Study officials:
References:
Clinical trial NCT01774552: Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment
Official title: A Pilot Study of Photo Acoustic Microscopy and Optical Coherence Tomography Imaging Technologies to Evaluate the Port-wine Stain Birthmark Treatment Before and After Pulsed Dye Laser Treatment.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Port-wine Stain
Lead sponsor: University of California, Irvine
Sponsor class: OTHER
Collaborators: name: Beckman Laser Institute University of California Irvine
First posted: 2013-01-24
Enrollment: 4
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Study population will be selected from Beckman Laser Medical Clinic, UCI

Brief summary: Port-wine stain is a congenital, progressive vascular malformation of human skin involving post-capillary venules that occurs in an estimated 0.3% of children and can alter personality development and psychological in children.

Detailed description: The researchers at University of California, Irvine and Washington University in Saint Louis are collaborating in this project and developes new multiple imaging devices call photoacoustic microscopy and optical coherence tomography imaging technologies can be use to evaluate the response of port-wine stain from Pulse Dye Laser treatment.

Eligibility criteria: Inclusion Criteria:

* All age with diagnosis of Port-wine stain

Exclusion Criteria:

* No diagnosis of Port-wine stain

Primary outcomes:
measure: evaluate the port-wine stain birthmark
timeFrame: up to 12 months
Secondary outcomes:
Other outcomes:
Locations:
city: Irvine
country: United States
facility: Beckman Laser Institute Medical Clinic
state: California
Study officials:
affiliation: Beckman Laser Institute, UCI
name: Wancun Jia, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02622152: Right Lateral Positioning of Postoperative Pediatric Cardiac Surgery
Official title: Right Lateral Positioning of Postoperative Pediatric Cardiac Surgery: Effect on Arterial Oxygenation, Respiratory Mechanics, Hemodynamics, and Adverse Events
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Heart Defects, Congenital
Keywords: Right lateral
Oxygenation
Cardiac
Congenital
Pediatric
Postoperative
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2015-12-04
Enrollment: 60
Sex: ALL
Minimum age (years): 1
Maximum age (years): 10
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Directly following cardiac surgery for congenital heart disease; patients are not receiving routine turning every two hours to prevent pressure ulcers, because a negative influence on hemodynamic parameters is assumed. Investigators have suggested that lateral position may have clinically significant effects on oxygenation in cardiac surgery patients.

Detailed description: Sixty pediatric congenital heart disease patients were randomly assigned to two equal intervention groups

Eligibility criteria: Inclusion Criteria:

* Age within 10 years with a cyanotic congenital heart disease
* Hemodynamic stability with no compromising arrhythmia
* No respiratory arrest
* Not connected with mechanical ventilation

Exclusion Criteria:

* Cyanotic congenital heart disease
* Hemodynamic instability

Primary outcomes:
measure: Arterial oxygenation
timeFrame: Duration of Intensive Care Unit Admission after weaning from mechanical ventilation an expected average of 4 days
Secondary outcomes:
measure: Blood pressure
timeFrame: Duration of Intensive Care Unit Admission after weaning from mechanical ventilation an expected average of 4 days
measure: Heart rate
timeFrame: Duration of Intensive Care Unit Admission after weaning from mechanical ventilation an expected average of 4 days
measure: Oxygen saturation
timeFrame: Duration of Intensive Care Unit Admission after weaning from mechanical ventilation an expected average of 4 days
measure: Respiratory rate
timeFrame: Duration of Intensive Care Unit Admission after weaning from mechanical ventilation an expected average of 4 days
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Faculty of Medicine
Study officials:
affiliation: associate professor
name: sayed abd elshafy, MD
role: PRINCIPAL_INVESTIGATOR
References: