Clinical trial NCT05314634: The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Official title: The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Executive Function
Keywords: acute exercise
concurrent exercise
cognitive flexibility
Lead sponsor: National Taiwan Normal University
Sponsor class: OTHER
First posted: 2022-04-06
Enrollment: 78
Sex: ALL
Minimum age (years): 21
Maximum age (years): 28
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Participants were randomly assigned to three group, namely the concurrent exercise group (CE), the aerobic exercise group (AE), and the reading control group (RC). Participants in CE groups were asked to finish 5 min warm-up, 12 min aerobic exercise, 13 min resistance exercise, and 5 min cool down. Participants in the AE group were asked to finish 5 min warm-up, 25 min aerobic exercise, and 5 min cool down. Participants in RC group were required to finish 35 min reading. All groups took a 30 min cognitive test before and after the intervention. The blood lactate were collected before, 17 minutes after, and after the intervention.
Primary purpose: TREATMENT

Brief summary: Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Detailed description: Executive function is a high-level cognition which plays an important role in academic performance, career, and interpersonal relationship. Meta-analysis study has demonstrated that acute exercise could improve executive function, and also observed similar positive effect through both aerobic and resistance exercise. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Eligibility criteria: Inclusion Criteria:

1. no history of psychiatric or neurological disorders
2. no history of cardiovascular disease
3. normal or corrected to normal vision and normal color perception
4. right handed
5. 18.5 \< BMI \< 27

Exclusion Criteria:

1. Diagnosed with epilepsy

Primary outcomes:
measure: Task Switch Test Response Times
timeFrame: 30 minutes
Secondary outcomes:
Other outcomes:
measure: Blood Lactate
timeFrame: before intervention, 17 minutes after intervention, and immediately after the 35 minute intervention
measure: Stroop Task
timeFrame: 30 minutes
Locations:
city: Taipei
country: Taiwan
facility: Department of Physical Education and Sport Sciences, National Taiwan Normal University
Study officials:
affiliation: Department of Physical Education and Sport Sciences, National Taiwan Normal University
name: Yu-Kai Chang, Ph.D.
role: STUDY_DIRECTOR
References: