Clinical trial NCT03254316: Health Care Associated Infection Surveillance in NICU
Official title: Healthcare Associated Infection Surveillance in NICU of Assiut University Children's Hospital
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Health Care Associated Infection
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2017-08-18
Enrollment: 100
Sex: ALL
Minimum age (years): 1
Maximum age (years): 28
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This is a prospective clinical study covered a period of 12 months in a tertiary neonatal intensive care unit in NICU of Assiut university children's hospital.

Brief summary: Healthcare - Associated Infection Surveillance In Neonatal Intensive Care Unit of Assiut University Children's Hospital.The objective of study is to determine the incidence, infection sites, causative organisms and risk factors related to healthcare-associated infections in NICU in Assiut University Children hospital.

Detailed description: Nosocomial infections (NIs) are a major public health problem worldwide . Nosocomial infections are those acquired in or associated with hospitals. They are also known as hospital-acquired or healthcare-associated infections. The usual deﬁnition of a hospital-acquired infection is one that was not present or incubating when the patient was admitted to a hospital or healthcare facility; where there is doubt, a cut-off period of 48 hours after admission is used.The terms hospital-acquired and healthcare-associated are often used interchangeably, but 'healthcare-associated' also has the wider meaning of any infection acquired as a result of healthcare in any setting.

Nosocomial infections are common, and may be serious or fatal. Some are unavoidable but doctors' duty of care to their patients extends to fundamental matters such as basic hygiene, which may prevent patients becoming infected, and avoidance of unnecessary antibiotics, to discourage development of resistance Health care-associated infections (HC-AIs) are a major cause of morbidity and mortality in neonatal intensive care units (NICUs) and lead to increases in hospital length of stay and treatment cost. Higher nosocomial infection incidence in NICUs was related to longer duration of hospital stay, and invasive interventions and medical treatments. HC-AIs, especially device-associated health care-associated infections (DA-HAIs), were also common in newborns because of their insufﬁcient immune system and mechanical barriers, as well as lack of protective ﬂora

Eligibility criteria: Inclusion Criteria:

1. Age at admission ( 0-28 DAY )
2. Neonates who admitted for more than 48 hours

Exclusion Criteria:

1. Age:more than 28days
2. Neonates who admitted for less than 48 hours.
3. Neonates who admitted for infection reasons as (pneumonia, MAS, AGE and skin infection).
4. Neonates with potentially infection (PROM, chorioamnionitis, TOF)
5. Neonates with congenital infections

Primary outcomes:
measure: Detect incidence of nosocomial infection in NICU
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Assiut university hospital
Study officials:
affiliation: Assiut University
name: Asmaa Shorat, Professor
role: STUDY_DIRECTOR
References: