Clinical trial NCT01502722: Effect of Ingestion of Sugary Drinks on Thirst Sensation
Official title: Effect of Ingestion of Sugary Drinks on Thirst Sensation
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Thirst
Lead sponsor: Universidade do Porto
Sponsor class: OTHER
First posted: 2012-01-02
Enrollment: 24
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: DIAGNOSTIC

Brief summary: The purpose of this study is to determine if regular soft drinks (with sugar) have the same effect on thirst as diet soft drinks(with sweeteners).

Detailed description: Participants should be in the laboratory at 8.00 in order to collect the values of weight, height, total body water, intracellular water and extracellular water in a Segmental Multi Frequency Body Composition Monitor (TANITA MC 180 MA®). Then, a blood sample will be collected for analysis of blood glucose and osmolality. They will sit at individual tables for the duration of the session and were allowed to read, listen to music with earphones, or use their portable computers with the exception of internet access to minimize visual cues (e.g., unwanted publicity for beverages or visiting Web sites showing pictures of food and drinks), which may have effect on thirst. Breakfast will be served at 9.30 on every occasion and preload stimuli will be offered exactly 60 minutes after breakfast (at 10.30). Lunch will be provided at 13.00. Motivational ratings will be first obtained at the end of collection of blood sample (baseline or time 0) and every 30 minutes thereafter until the lunch time (times 1 through 7). After lunch (time 8), participants will complete the last set of ratings and will bring a food diary to record all food and fluid intake until 00.00 that day.

Eligibility criteria: Inclusion Criteria:

* body mass index(BMI) between (18,5 - 25 kg/m2)
* regular consumers of breakfast
* stable in weight for the past 6 months
* not dieting to gain or lose weight
* like all drinks and food available in study

Exclusion Criteria:

* pregnant and nursing women
* smokers
* athletes
* subjects under medication(except oral contraceptives in women)

Primary outcomes:
measure: Motivational Ratings
timeFrame: 1 day
Secondary outcomes:
measure: Food Behavior After Intervention
timeFrame: 1 day
measure: Amount of water ingested
timeFrame: 1 day
Other outcomes:
Locations:
city: Porto
country: Portugal
facility: Faculdade de Ciências da Nutrição e Alimentação da Universidade do Porto
Study officials:
affiliation: Faculdade de Ciências da Nutrição e Alimentação - Universidade do Porto
name: Pedro R Carvalho, PhD Student
role: PRINCIPAL_INVESTIGATOR
affiliation: Faculdade de Ciências da Nutrição e Alimentação - Universidade do Porto
name: Vitor H Teixeira, PhD
role: STUDY_DIRECTOR
References:
citation: Monsivais P, Perrigue MM, Drewnowski A. Sugars and satiety: does the type of sweetener make a difference? Am J Clin Nutr. 2007 Jul;86(1):116-23. doi: 10.1093/ajcn/86.1.116.
citation: Almiron-Roig E, Drewnowski A. Hunger, thirst, and energy intakes following consumption of caloric beverages. Physiol Behav. 2003 Sep;79(4-5):767-73. doi: 10.1016/s0031-9384(03)00212-9.