Clinical trial NCT04770558: Effectiveness of Interactive Exergame in Older Adults With Sarcopenia
Official title: Effectiveness of Interactive Exergame to Improve Physical and Cognitive Functions in Older Adults With Sarcopenia
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Sarcopenia
Lead sponsor: Taipei Medical University
Sponsor class: OTHER
First posted: 2021-02-25
Enrollment: 60
Sex: ALL
Minimum age (years): 65
Maximum age (years): 99
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Sarcopenia has been defined as an age related, involuntary loss of skeletal muscle mass and strength. The prevalence of sarcopenia is about 10% globally, and risk factors of sarcopenia includes age, lower physical activity, and malnutrition. Sarcopenia can lead to many adverse health outcomes, particularly in physical and cognitive functions. Most of previous studies have reported that interactive exergame can improve cognitive and physical functions in older population but none of studies use of interactive exergame on older adults with sarcopenia. Therefore, the aim of study will investigate the effects of interactive exergame on older adults with sarcopenia.

Detailed description: A total of 60 older participants will be randomly assigned to the experimental and control groups. Participants in the experimental group will receive 40 minutes per session, 2 times a week for 12 weeks interactive exergame while those in the control group will maintain their regular activity. All participants will be assessed their physical and cognitive function, sarcopenia index and other health related outcome measurements before and after intervention program.

Eligibility criteria: Inclusion Criteria:

1. 65-99 years old
2. able to walk 6 meters without assistance devices
3. older adults with possible sarcopenia, sarcopenia or severe sarcopenia

Exclusion Criteria:

1. people with hemodialysis
2. people with built-in electronic medical equipment
3. people with central nervous system disease such as stroke or Parkinson's disease
4. score in ascertain dementia 8 more than 2
5. people with mental illness

Primary outcomes:
measure: Hand grip
timeFrame: Change from Baseline hand grip at Week 12
measure: Lower limbs strength
timeFrame: Change from Baseline lower limbs strength at Week 12
measure: Appendicular muscle mass
timeFrame: Change from Baseline appendicular muscle mass at Week 12
measure: Function ability
timeFrame: Change from Baseline function ability at Week 12
measure: Static balance
timeFrame: Change from Baseline static balance at Week 12
measure: Walking ability
timeFrame: Change from Baseline walking ability at Week 12
measure: Fear of falling
timeFrame: Change from Baseline fear of falling at Week 12
measure: Cognitive function
timeFrame: Change from Baseline cognitive function at Week 12
Secondary outcomes:
measure: Physical Activity
timeFrame: Change from Baseline physical activity at Week 12
measure: Diet record
timeFrame: Change from Baseline diet record at Week 12
measure: Depression
timeFrame: Change from Baseline depression at Week 12
measure: Health-related quality of life
timeFrame: Change from Baseline health-related quality of life at Week 12
Other outcomes:
measure: Sarcopenia screening
timeFrame: Baseline
measure: Dementia screening
timeFrame: Baseline
Locations:
city: Taipei
country: Taiwan
facility: Community daycare center
Study officials:
affiliation: School of Gerontology Health Management
name: Shu-Chun Lee, PhD
role: PRINCIPAL_INVESTIGATOR
References: