Clinical trial NCT04788134: Post- Rotatory Nystagmus Test: Normative Data for Spanish Adolescents and Adults
Official title: Normative Data for Post-rotatory Nystagmus Test at Spanish Adolescent and Adult Population: a Transversal Study
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Vestibular Function Tests
Nystagmus Vestibular
Keywords: vestibular function tests
nystagmus, physiologic
adult
adolescent
Lead sponsor: Quesada, Rocío Vico
Sponsor class: INDIV
First posted: 2021-03-09
Enrollment: 163
Sex: ALL
Minimum age (years): 13
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: People over 13 years, that lives in the north, middle and south of Spain, and meet the selection criteria.

Brief summary: The vestibulo-ocular reflex is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head. The post-rotational nystagmus test (PRN) assesses the integrity of this reflex, thus assessing the perception of the vestibular system. The duration of this reflex after administering this test has been widely studied in children from 2 months to 12 years and 11 months of age. However, there is a knowledge gap from that age that the present study seeks to address.

Detailed description: The vestibulo-ocular reflex (VOR) is the motor response of our eyes in the opposite direction to a translational or rotational movement of our head. The post-rotational nystagmus test (PRN) assesses the integrity of this reflex, thus assessing the perception of the vestibular system. This system has an important role in our balance, stabilization of the visual field when our head moves, awareness of the position of our head in space, postural control and functions of the Autonomous Nervous System.

The duration of this reflex after administering this test has been widely studied in children from 2 months to 12 years and 11 months of age. However, there is a knowledge gap from that age that the present study seeks to address. This article aims to explore the use of the PRN test for adolescent and adults, to prove if the duration of the VOR is longer in these population than in children. It will be also recollected personal data to study whether exposure to vestibular input influences its reactivity and perception.

Eligibility criteria: Inclusion Criteria:

* People over 13 years of age.
* Spanish-speaking population.
* Signature of the informed consent.

Exclusion Criteria:

* Diagnosis of a neurodevelopmental or neurological disorder.
* Being in occupational therapeutic treatment for balance or vestibular problems.
* Practice of sports in one previous hour.
* Adverse reaction to vestibular input such as vomiting, discoloration, feeling of unpleasantness or any other type of negative reaction before / during / after the administration of the NPR.

Primary outcomes:
measure: Duration of vestibular-ocular reflex after the administration of nystagmus post-rotatory test in adolescent and adult population
timeFrame: End of the nystagmus post rotatory test and end of the vestibular-ocular reflex
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Quesada, Rocío Vico
name: Vico Rocío
role: PRINCIPAL_INVESTIGATOR
affiliation: Quesada, Rocío Vico
name: Pedrero Yolanda
role: PRINCIPAL_INVESTIGATOR
affiliation: Quesada, Rocío Vico
name: Zisa Nerina
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mailloux Z, Leao M, Becerra TA, Mori AB, Soechting E, Roley SS, Buss N, Cermak SA. Modification of the postrotary nystagmus test for evaluating young children. Am J Occup Ther. 2014 Sep-Oct;68(5):514-21. doi: 10.5014/ajot.2014.011031.