Clinical trial NCT06303219: Effects of Traditional Moderate Intensity Training and High Intensity Interval Training in Polycystic Ovarian Syndrome
Official title: Comparative Effects of Traditional Moderate Intensity Training and High Intensity Interval Training on Anxiety, Fatigue and Quality of Life in Polycystic Ovarian Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Polycystic Ovarian Syndrome
Keywords: Anxiety
Fatigue
High Intensity Interval Training
Polycystic Ovarian Syndrome
Quality of Life.
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-03-12
Enrollment: 44
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To determine the comparative effects of traditional moderate intensity training and high intensity interval training on Anxiety, fatigue and Quality of Life in females with polycystic ovarian syndrome


Eligibility criteria: Inclusion Criteria:

* Participants with BMI greater than 25kg/m2
* Oligo- or anovulation/irregular cycles i.e 35 days
* Married women
* Primary infertility
* A diagnosis of polycystic ovaries based on ultrasound results

Exclusion Criteria:

* Use of psychiatric or psychotropic medications.
* Unresolved gynecological conditions i.e Cervical Dysplasia, Pelvic floor prolapse, Uterine Fibroids, Urinary Incontinence
* Diabetes, pregnancy, smoking, illness or injury that prevented or limited exercise performance and existing participation in regular physical activity

Primary outcomes:
measure: Hamilton Anxiety Rating scale (HAM-A)
timeFrame: 4th week
measure: The Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (PCOSQ)
timeFrame: 4th week
measure: The Fatigue Impact Scale (FIS)
timeFrame: 4th week
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Gynecological Department of Fatima Memorial Hospital
Study officials:
affiliation: Riphah International University
name: hina gul
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Teede HJ, Tay CT, Laven JJE, Dokras A, Moran LJ, Piltonen TT, Costello MF, Boivin J, Redman LM, Boyle JA, Norman RJ, Mousa A, Joham AE; International PCOS Network. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Eur J Endocrinol. 2023 Aug 2;189(2):G43-G64. doi: 10.1093/ejendo/lvad096.
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citation: Kite C, Parkes E, Taylor SR, Davies RW, Lagojda L, Brown JE, Broom DR, Kyrou I, Randeva HS. Time to Load Up-Resistance Training Can Improve the Health of Women with Polycystic Ovary Syndrome (PCOS): A Scoping Review. Med Sci (Basel). 2022 Sep 22;10(4):53. doi: 10.3390/medsci10040053.
citation: Patel V, Menezes H, Menezes C, Bouwer S, Bostick-Smith CA, Speelman DL. Regular Mindful Yoga Practice as a Method to Improve Androgen Levels in Women With Polycystic Ovary Syndrome: A Randomized, Controlled Trial. J Am Osteopath Assoc. 2020 Apr 14. doi: 10.7556/jaoa.2020.050. Online ahead of print.
citation: Abdollahi L, Mirghafourvand M, Babapour JK, Mohammadi M. Effectiveness of cognitive-behavioral therapy (CBT) in improving the quality of life and psychological fatigue in women with polycystic ovarian syndrome: a randomized controlled clinical trial. J Psychosom Obstet Gynaecol. 2019 Dec;40(4):283-293. doi: 10.1080/0167482X.2018.1502265. Epub 2018 Sep 3.
citation: .Jakhar R, Sen ED, Rastogi P. Improvement In Health-Related Quality of Life in Polycystic Ovarian Syndrome: A Randomized Controlled Trial. Journal of Survey in Fisheries Sciences. 2023:382-8.
citation: Ashila A, Murugaraj T. Effect of High Intensity Interval Training on Body Mass Index, Plasma Glucose and Insulin Among Individuals with Polycystic Ovary Syndrome Living in the South Indian Coast. Journal of Coastal Life Medicine. 2023;11:2579-85