Clinical trial NCT04217070: Suicidal Poisoning in Emergency Units
Official title: Evaluation of Suicidal Poisoning Cases in Emergency Units of Assuit University Hospitals
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Poisoning
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2020-01-03
Enrollment: 303
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All patients presented to Emergency units of assiut university hospitals with suicidal poisoning attemps

Brief summary: Poisoning is the deterioration of the body's functions by the ingestion of any substance being toxic to the body or by overdosing a nontoxic substance. Poisoning cases may vary according to the geographical and seasonal characteristics of the region, sociocultural structure of the population, life index and the age groups.

Worldwide, intentional self-poisoning (ISP) is the most common form of suicide attempt and the most common method that results in medical hospitalization.

Detailed description: Questionnaire is prepared including the following items:

Demographic data:

Gender -age-marital status -occupation- socioeconomic state -special habit -history of psychiatric innless-history of chronic diseases-history of drug dependence -previous suicidal attempts-toxic substance used in suicide- time of poisoning, season and time of arrival .

Data regarding poisoned substance:

Dose, type of the substance used and rout of administration. Presenting symptoms of intoxication and management

Complete clinical examination:

General condition: conscious level and vital signs. Local examination: chest, heart, abdomen, etc.

Investigation:

(Arterial blood gases - ECG -otherwise according to case presentation)

Prognosis:

Complete recovery, complications, death.

Eligibility criteria: Inclusion Criteria:

* suicidal poisoning cases

Exclusion Criteria:

* other causes of suicide

Primary outcomes:
measure: Determination of the prevalence of suicidal poisoning cases attending emergency units, Assuit university hospitals
timeFrame: One year
Secondary outcomes:
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Assiut University Hospital
Study officials:
name: Randa H Abd-Elhady, prof
role: STUDY_DIRECTOR
name: Noha E Ebrahem, Dr
role: STUDY_DIRECTOR
References:
citation: Conner KR, Wiegand TJ, Gorodetsky R, Schult RF, Kaukeinen K. Poisoning Severity Associated with a Range of Medications in Suicide Attempts by Ingestion. Suicide Life Threat Behav. 2019 Jun;49(3):635-642. doi: 10.1111/sltb.12468. Epub 2018 Apr 25.
citation: Kanchan T, Menezes RG. Suicidal poisoning in Southern India: gender differences. J Forensic Leg Med. 2008 Jan;15(1):7-14. doi: 10.1016/j.jflm.2007.05.006. Epub 2007 Sep 5.
citation: Kazanasmaz H, Kazanasmaz O, Calik M. Epidemiological and sociocultural assessment of childhood poisonings. Turk J Emerg Med. 2019 Jun 20;19(4):127-131. doi: 10.1016/j.tjem.2019.06.001. eCollection 2019 Oct.
citation: Piekarska-Wijatkowska A, Kobza-Sindlewska K, Rogaczewska A, Zajdel R, Krakowiak A. Intentional poisoning among elderly people-residents of a large urban agglomeration in Poland. Hum Exp Toxicol. 2016 Dec;35(12):1328-1336. doi: 10.1177/0960327116630353. Epub 2016 Feb 9.
citation: Klonsky ED, May AM, Saffer BY. Suicide, Suicide Attempts, and Suicidal Ideation. Annu Rev Clin Psychol. 2016;12:307-30. doi: 10.1146/annurev-clinpsy-021815-093204. Epub 2016 Jan 11.