Clinical trial NCT06517134: Prescribing Patterns of Antihypertensive Drugs in Uncomplicated Hypertension
Official title: Association Between GP Characteristics and Prescription Patterns for Antihypertensive Drugs: A Cross-sectional Study in Normandy, France
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hypertension,Essential
Cardiovascular Diseases
Keywords: hypertension
prescriptions
primary care
Lead sponsor: University Hospital, Caen
Sponsor class: OTHER
First posted: 2024-07-24
Enrollment: 3325032
Sex: ALL
Minimum age (years): 18
Maximum age (years): 99
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The participant pool for this study comprised GP characteristics and prescription practices within the Normandy region in northwestern France during the course of 2019. With a resident population of 3,325,032 as of January 1, 2019, and a total of 2,165 registered GPs, the study was well-situated to offer a representative analysis.

In order to focus on conventional full-time primary GP care, practitioners whose primary professional focus included specialties such as osteopathy, acupuncture, homeopathy, or nutrition were excluded. Furthermore, GPs with fewer than 300 annual consultations/visits (less than one per day), fewer than 2,000 annual drug prescriptions, no patients with any of the 30 chronic diseases that qualify for no-charge treatment under French law, or solely very low-income patients (eligible for no-charge GP visits as defined by French legislation) were also excluded.

Brief summary: Hypertension incurs substantial cardiovascular morbidity and mortality, particularly in primary prevention settings. General practitioners (GPs) play a pivotal role in the management of hypertension in primary care, yet variations exist among GPs. The determinants shaping GPs' antihypertensive medication (AD) prescription patterns in the setting of hypertension remain ambiguous. This investigation sought to elucidate how GPs' characteristics and professional activities influence AD prescriptions. A cross-sectional study utilizing a sample of 2,165 GPs was conducted in Normandy, France, in 2019. The ratio of AD prescriptions to overall prescription volume was computed for each practitioner. GPs were classified as 'low' or 'high' AD prescribers based on the median of this ratio. The ratio was examined in relation to GPs' demographic and professional variables such as age, gender, practice setting, years of experience, consultation frequency, the demographics and socioeconomic status of their patient panels, and prevalence of chronic conditions in patients. These associations were explored using both univariate and multivariate analyses.


Eligibility criteria: Inclusion Criteria:

* All patients who had at least one visit to their GP in 2019 were included, but minors were omitted.

Exclusion Criteria:

* minors

Primary outcomes:
measure: GP demographics
timeFrame: 1 year
measure: medical practice activities
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Caen
country: France
facility: Xavier Humbert
Study officials:
References: