Clinical trial NCT05479799: Prevalence and Determinants of Anemia During the Third Trimester of Pregnancy
Official title: Prevalence and Determinants of Anemia During the Third Trimester of Pregnancy
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Anemia of Pregnancy
Keywords: Anemia
Hemoglobin
Third trimester
Pregnancy outcome
Lead sponsor: Beni-Suef University
Sponsor class: OTHER
First posted: 2022-07-29
Enrollment: 383
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 42
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: The study included pregnant women who attended the antenatal care clinic during their third trimester.

Brief summary: This cross-sectional study was conducted on 383 pregnant women who attended the antenatal care clinic during their third trimester at Beni-Suef University Hospital.

A proper history was taken from each participant. All women were subjected to routine antenatal care, including physical examinations, ultrasound examinations, and routine laboratory tests.

According to WHO criteria, anemia was diagnosed with a hemoglobin level of less than 11.0 g/dl. Anemia was further divided into three degrees; mild with hemoglobin level 10-10.9 g/dl, moderate with hemoglobin level 7-9.9 g/dl, and severe with hemoglobin level \< 7.0 g/dl.

Detailed description: This cross-sectional study was conducted on 383 pregnant women who attended the antenatal care clinic during their third trimester at Beni-Suef University Hospital.

A proper history was taken from each participant regarding age, educational level, residency (urban or rural), occupation, family income, frequency of antenatal visits, obstetric history, medical history, and surgical history. Nutritional history is taken to detect the frequency intake of meat/month, chicken/week, fish/week, fruits/week, vegetables/week, and tea/day. History of iron supplements intake was taken. All women were subjected to routine antenatal care, including a physical examination (e.g., measuring blood pressure), ultrasound, and umbilical artery Doppler examination. A blood sample was taken from each enrolled woman for standard laboratory tests such as complete blood picture, blood group, RH type, and blood sugar test if there is a risk. A urine sample was taken for urine analysis. Blood from each participant was drawn from the cubital vein into appropriate blood collection tubes using vacuum tube needles (Becton Dickinson Medical Devices Co. Ltd., Franklin Lakes, USA). K2EDTA tubes were used for CBC. Samples were transported and tested within 4 hours after collection. Measured CBC parameters included RBC, HGB, HCT, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), MCH concentration (MCHC), platelet count (PLT), WBC, and WBC differentials, including percentages and absolute counts of neutrophils (NEUT% and NEUT), lymphocytes (LYM% and LYM), monocytes (MONO% and MONO), basophils (BASO% and BASO), and eosinophils (EO% and EO).

According to WHO criteria, anemia was diagnosed with a hemoglobin level of less than 11.0 g/dl. Anemia was further divided into three degrees; mild with hemoglobin level 10-10.9 g/dl, moderate with hemoglobin level 7-9.9 g/dl, and severe with hemoglobin level \< 7.0 g/dl.

Eligibility criteria: Inclusion Criteria:

* pregnant women during their third trimester

Exclusion Criteria:

* Women with chronic medical illness

Primary outcomes:
measure: Number of participants with the prevalence of anemia in the third trimester of pregnancy
timeFrame: through study completion (3-6 months)
Secondary outcomes:
Other outcomes:
Locations:
city: Banī Suwayf
country: Egypt
facility: Beni-Suef University
Study officials:
References: