Clinical trial NCT06311539: The Effect of Circadian Rhythm on Physical Performance in Healthy Male Individuals
Official title: The Effect of Chronotype and Circadian Rhythm on Physical Performance in Healthy Male Individuals
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Chronotype
Exercise
Keywords: circadian rhythm
chronotype
physical performance
Lead sponsor: Istanbul Bilgi University
Sponsor class: OTHER
First posted: 2024-03-15
Enrollment: 60
Sex: MALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized Controlled Study
Primary purpose: SCREENING

Brief summary: Little is known about optimizing the timing of exercise periods to maximize the health benefits of exercise. Furthermore, exercise is a potent modulator of skeletal muscle metabolism and it is clear that skeletal muscle has a robust circadian profile. Circadian rhythms can be observed in behavior, physiology, and metabolism. Various studies show that exercise changes the rhythm of the clock machines in skeletal muscle. Studies examining the relationship between exercise, especially strength training, and circadian rhythm are quite limited in the literature. Although some studies have shown that force peaks in the afternoon/evening hours, regardless of muscle group and contraction speed, there are no studies on how much this time interval varies from person to person and chronotype.

The aim of this study is to investigate to what extent strength training given at appropriate times for morning, evening and intermediate chronotypes creates changes in performance in healthy adult male individuals.

Detailed description: After participants are informed about the research, evaluation and exercise protocol, their signed consent will be obtained.

The Morningness-Eveningness Questionnaire will be applied until 30 participants with morning type and 30 evening type chronotypes are reached. (Estimated for 100 students) After determining 30 morning type and 30 evening type participants, isokinetic evaluations will be made and vertical jump heights will be measured (T0).

Then, 15 morning type participants will be included in the morning exercise program (08:00) and 15 morning type participants will be included in the evening exercise program (18:00).

15 evening type participants will be included in the morning exercise program (08:00) and 15 evening type participants will be included in the evening exercise program (18:00).

Thus, some of the participants from both morning and evening groups will be included in strength training for 6 weeks, at a time appropriate to their chronotypes, and some at a time incompatible with their chronotypes. Isokinetic evaluations and vertical jump height measurements will be repeated at the end of the strengthening exercise program, which will last 3 days a week for 6 weeks, a total of 18 sessions.

Eligibility criteria: Inclusion Criteria:

* Being male,
* Between the ages of 18-30
* Having a chronotype that was morning person or evening person in the Morningness-Eveningness Questionnaire

Exclusion Criteria:

* Being female
* Having an intermediate chronotype in the Morningness-Eveningness Questionnaire
* Having a history of surgery or limitation in the knee area
* Having a metabolic, neurological, or orthopedic disorder.

Primary outcomes:
measure: Isokinetic strength test
timeFrame: T0 and T1 (Baseline and after 6 week exercise program)
measure: Vertical jump test
timeFrame: T0 and T1 (Baseline and after 6 week exercise program)
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Marmara University, Faculty of Health Sciences
name: Ilksan Demirbuken, PhD
role: STUDY_DIRECTOR
affiliation: Marmara University, Faculty of Health Sciences
name: Ender Ersin Avci, PhD
role: STUDY_DIRECTOR
affiliation: Marmara University
name: Mine Gulden Polat, PhD
role: STUDY_DIRECTOR
References: