Clinical trial NCT06610006: Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults
Official title: Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Pre Hypertension
Lead sponsor: Foundation University Islamabad
Sponsor class: OTHER
First posted: 2024-09-24
Enrollment: 44
Sex: ALL
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: This is a randomized controlled trial having two groups. One group(interventional group) will be doing High Intensity Training (HIIT) and Isometric Wall Squat and the other group (control group) will be doing High intensity Interval Training (HIIT).
Primary purpose: TREATMENT

Brief summary: Hypertension is leading yet preventable risk factor for cardiovascular disease and all-cause mortality worldwide. Prehypertension identifies those at high risk of developing HTN, prompting intervention to prevent or delay the onset of the disease. High intensity interval training (HIIT) is a time efficient mode of training with established benefits, while Isometric wall squats (IWS) also provide a range of proven benefits and advantages, but their combined effect on BP measures is yet to be determined.Hence the objective of this study is to compare the effects of isometric wall squats along with high intensity interval training versus high intensity interval training alone on rate pressure product, SBP and DBP, heart rate and anthropometric measures in normotensive and pre-hypertensive sedentary adults

Detailed description: Pre-Hypertension is not a disease itself rather it categorizes those who are at the risk of developing hypertension in future. By targeting pre-hypertensive and normotensive individuals we are focusing on preventive measures, potentially reducing incidence of HTN and cardiovascular conditions in future. If found effective, this study can help in providing training protocols while also decreasing the risk of hypertension in future.A total of 15 sessions of high intensity interval training alone in one group and combination of high intensity interval and isometric wall squat in other group, for thrice a week on alternative days for 5 consecutive weeks will be given.

Eligibility criteria: Inclusion Criteria:

* Both male and female adults aged 18-45 years.
* Participants lying in Low PA (inactive) category on basis of IPAQ.
* Pre-hypertensive adults:
* SBP- 120 mmHg or more and \<140 mmHg
* DBP of 80 mmHg or more and \< 90 mmHg.
* Normotensive adults: SBP \< 120 mmHg and DBP \< 80 mmHg. Exclusion Criteria
* Diagnosed with any current infections.
* Subjects with any diagnosed cardiovascular or respiratory conditions.
* Subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program.
* Active Smokers
* Those with any contraindication to exercise testing or training.
* Pregnant females

Primary outcomes:
measure: Rate Pressure Product
timeFrame: 5 weeks
measure: Blood Pressure(SBP and DBP)
timeFrame: 5 weeks
measure: Heart rate
timeFrame: 5 weeks
measure: Anthropometric Measures Waist circumference
timeFrame: 5 weeks
measure: Anthropometric Measures hip circumference
timeFrame: 5 weeks
measure: Anthropometric Measures Waist to hip ratio
timeFrame: 5 weeks
measure: BMI
timeFrame: 5 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Foundation University College of Physical Therapy
state: Punjab
Study officials:
References: