Clinical trial NCT03697642: Nasopharyngeal Airway Guide Nasogastric Tube Placement
Official title: A Nasopharyngeal Airway Facilitates Nasogastric Intubation in Anesthetized Intubated Patients: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Nasogastric Tube
Nasopharyngeal Airway
Anesthesia, General
Lead sponsor: Chang Gung Memorial Hospital
Sponsor class: OTHER
First posted: 2018-10-05
Enrollment: 108
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Nasogastric tube placement is essential for various surgery and critically ill patients. However, NG tube insertion in anesthetized, paralyzed, and intubated or unconscious patients may be difficult, with reported success rate less 50% on the first attempt without any auxiliary devices. Endotracheal tube intubation narrow the space of oropharynx and hypopharynx. Loss ability to swallow and tongue drop also made the NG tube coil in the mouth easily. Investigators assume nasopharyngeal airway can facilitate NG tube insertion by opening a channel from nostril to epiglottis and reduce complications by protecting nasal cavity while inserting NG.


Eligibility criteria: Inclusion Criteria:

* Patient should be \> 20 years old, ASA 1\~3 under going schedule general anesthesia with endotracheal tube intubation
* Patient who required NG tube placement for perioperative care

Exclusion Criteria:

* Coagulation abnormality (PLT≤100000, INR\>1.2 \& PT≥13)
* Hemodynamic unstable (with inotropic agent use)
* Arrythmia
* Esophageal varices or stricture, Esophageal cancer, trauma or previous esophageal surgery
* Gastric cancer involve cardiac orifice
* Corrosive chemical (strong acid or alkali) ingestion
* Skull base fracture
* Recent nasal surgery, nasal fracture or severe nasal obstruction
* Loose teeth that make endotracheal tube can not fix right side

Primary outcomes:
measure: First attempt successful rate
timeFrame: can be know after NG tube placement immediately
measure: Second attempt successful rate
timeFrame: can be know after NG tube placement immediately
measure: Overall successful rate insertion
timeFrame: can be know after NG tube placement immediately
measure: Time cost during NG tube placement
timeFrame: can be know after NG tube placement immediately
Secondary outcomes:
measure: Incidence of NG tube coiling
timeFrame: can be know after NG tube placement immediately
measure: Incidence of NG tube kinking
timeFrame: can be know after NG tube placement immediately
measure: Incidence of NG tube knotting
timeFrame: can be know after NG tube placement immediately
measure: Incidence of epistaxis after NG tube placement
timeFrame: can be know after NG tube placement immediately
measure: Mean blood pressure change after NG tube placement
timeFrame: can be know after NG tube placement immediately
measure: Heart rate change after NG tube placement
timeFrame: can be know after NG tube placement immediately
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Chang Gung Memorial Hospital
Study officials:
References:
citation: Huang TY, Lin JR, Chung YT. A preinstalled nasopharyngeal airway in the right nasal passageway to facilitate nasogastric intubation in anesthetized and intubated patients: a prospective randomized controlled trial. BMC Gastroenterol. 2020 Nov 3;20(1):365. doi: 10.1186/s12876-020-01514-6.