Clinical trial NCT04295434: Blood Pressure Control in ESH Excellence Centres
Official title: Study of the European Society of Hypertension on Blood Pressure Control in ESH Excellence Centres
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Blood Pressure
Lifestyle Risk Reduction
White Coat Hypertension
Keywords: Blood pressure
Hypertension
Control
European
Excellence centres
Lead sponsor: Clinical Hospital Centre Zagreb
Sponsor class: OTHER
Collaborators: name: European Society of Hypertension
First posted: 2020-03-04
Enrollment: 3000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Patients with hypertension that are under supervision of excellence centres participating in the study.

Brief summary: In the BP-CON-ESH study we are going to include and analyze treated hypertensive patients seen consecutively by the ESH Excellence Centres. Blood pressure will be measured as usually done in the office, but care will be adopted to make measurements highly standardized in all Centres. The primary goals will be to determine the global, regional and country rates of hypertension control in Europe. Other goals will be to identify global and regional factors associated with blood pressure control in different European regions. The results obtained in the BP-CON-ESH project will be used to refine treatment strategies for improvement of blood pressure control and will serve as a basis for assessing future changes and trends in Europe.

Detailed description: The most important task of the European Society of Hypertension is to improve blood pressure treatment and increase blood pressure control, thus decreasing cardiovascular risk, premature cardiovascular and renal morbidity and mortality, with in addition a reduction of health-care costs. More than a decade ago, the European Society of Hypertension established a network of Excellence Centres. Those centres are leading institutions for the diagnosis and treatment of hypertension and thus are front runners of good clinical practice in hypertension management in their countries. An important task of the Excellence Centres is also to be active in research, particularly in projects conducted by the European Society of Hypertension. The ongoing BP-CON-ESH project on the rate of blood pressure control in hypertensive patients addresses the most elementary,but at the same timethe most important aspect in hypertension management, because the observed low rates of blood pressure control is the reason why hypertension is still today the leading cause of death worldwide.

In the BP-CON-ESH study we are going to include and analyze treated hypertensive patients seen consecutively by the ESH Excellence Centres. Blood pressure will be measured as usually done in the office, but care will be adopted to make measurements highly standardized in all Centres.

The primary goals will be to determine the global, regional and country rates of hypertension control in Europe. Other goals will be to identify global and regional factors associated with blood pressure control in different European regions. It is well known that the overall control of hypertension in Europe is still insufficient. However, the problem is not the same across Europe. Differences in healthcare systems exist among European countries, and in some countries government healthcare system only partially reimburse costs of antihypertensive therapy. There are also differences in gross national product, educational levels, salt consumption, prevalence of obesity and other aspects. These could cause dissimilarities in hypertension prevalence, achieved blood pressure control and cardiovascular mortality among European regions.

The results obtained in the BP-CON-ESH project will be used to refine treatment strategies for improvement of blood pressure control and will serve as a basis for assessing future changes and trends in Europe.

Eligibility criteria: Inclusion Criteria:

* Signed informed consent

Exclusion Criteria:

* Pregnancy and breastfeeding
* Terminal malignancy, reduced life expectancy (\<6 months)
* Amputated limb
* Dementia
* Patients living in a nursing home
* Unsigned informed consent

Primary outcomes:
measure: Blood pressure control
timeFrame: Through study completion, an average of 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Yerevan
country: Armenia
facility: Center of Preventive Cardiology, Yerevan
city: Wels
country: Austria
facility: Klinikum Wels-Grieskirchen
city: Brussels
country: Belgium
facility: Erasmus Hospital
city: Liège
country: Belgium
facility: CHU de Liège
city: Mons
country: Belgium
facility: Ambroise Paré University Hospital
city: Sofia
country: Bulgaria
facility: University Hospital "St. Anna"
city: Zagreb
country: Croatia
facility: University hospital centre Zagreb
state: Grad Zagreb
city: Plzen
country: Czechia
facility: Charles University Medical School and University Hospital
city: Praha
country: Czechia
facility: Center for Hypertension, Charles University, Prague
city: Praha
country: Czechia
facility: Institute for Clinical and Experimental Medicine (IKEM) and Thomayer Hospital, Prague
city: Tallinn
country: Estonia
facility: Tallinn Hypertension Excellence Centre
city: Berlin
country: Germany
facility: Hypertension Center Berlin Charité
city: Bonn
country: Germany
facility: Hypertoniezentrum Bonn
city: Hanover
country: Germany
facility: Medizinische Hochschule Hannover
city: Homburg
country: Germany
facility: Universitätskliniken des Saarlandes
city: Munich
country: Germany
facility: Hypertension Center Munich
city: Athens
country: Greece
facility: Hypertension and Cardiovascular Prevention Clinic, 3rd Department of Medicine, Evangelismos Hospital
city: Athens
country: Greece
facility: Hypertension Clinic, University Hospital Laiko
city: Athens
country: Greece
facility: University of Athens, Hippokration Hospital
city: Athens
country: Greece
facility: Hypertension Clinic, Department of Cardiology, KAT General Hospital
city: Athens
country: Greece
facility: Hypertension Clinic, Cardiology Department, Asklepeion Hospital
city: Heraklion
country: Greece
facility: University Hospital of Heraklion
city: Ioánnina
country: Greece
facility: Hypertension Center, Department of Nephrology, University Hospital of Ioannina
city: Thessaloníki
country: Greece
facility: Hypertension Outpatient Clinic, 1st Propedeutic Dept. of Internal Medicine, AHEPA Hospital
city: Thessaloníki
country: Greece
facility: Hypertension Center, Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki
city: Thessaloníki
country: Greece
facility: Aristotle University of Thessaloniki, Papageorgiou General Hospital
city: Ashdod
country: Israel
facility: Assuta Ashdod University Hospital
city: Brescia
country: Italy
facility: Centre of Prevention and Treatment of Arterial Hypertension and Cardiovascular Risk Factors
city: Milan
country: Italy
facility: S. Luca Hospital, Istituto Auxologico Italiano
city: Milan
country: Italy
facility: Ospedale Niguarda, Dip. De Gasperis e Università di Milano Bicocca
city: Napoli
country: Italy
facility: Napoli Hypertension Excellence Centre, Federico II Clinic Research Center for Hypertension and Related Conditions
city: Torino
country: Italy
facility: Excellence Centre of Hypertension, Department of Medical Sciences, University of Torino
city: Beirut
country: Lebanon
facility: American University Center, Hypertension/Vascular Medicine Division (Associated Centre)
city: Kaunas
country: Lithuania
facility: Kaunas Hypertension Excellence Centre
city: Maastricht
country: Netherlands
facility: University Hospital Maastricht
city: Nijmegen
country: Netherlands
facility: Radboud University of Nijmegen Medical Center
city: Warsaw
country: Poland
facility: Department of Internal Medicine, Hypertension and Vascular Diseases, Warsaw Medical University
city: Guimarães
country: Portugal
facility: Centro Hospitalar do Alto Ave, Minho University
city: Bucharest
country: Romania
facility: Department of Cardiology and Internal Medicine, Emergency Clinical Hospital of Bucharest
city: Belgrad
country: Serbia
facility: Centre for Hypertension of the Clinical Centre of Serbia
city: Barcelona
country: Spain
facility: Hipertensión Clinic, Internal Medicine, Hospital Clinico, University of Barcelona
city: Córdoba
country: Spain
facility: Hypertension Clinic, Nephrology Department, Reina Sofia University Hospital
city: Stockholm
country: Sweden
facility: Danderyd University Hospital
city: Kyiv
country: Ukraine
facility: National Scientific Center "The M.D. Strazhesko Institute of Cardiology"
city: London
country: United Kingdom
facility: St. Bartholomew's Royal London School of Medicine & Dentistry
city: London
country: United Kingdom
facility: The Pearl-Rose Clinic (Hypertension & Cardiovascular Risk), Hammersmith Hospital,
Study officials:
affiliation: Clinical Hospital Centre Zagreb
name: Bojan Jelaković, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: