Clinical trial NCT01463917: Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery
Official title: Use of Hypertonic Versus Isotonic Solutions in Off Pump Coronary Artery Bypass Graft Surgery Targeting the Left Marginal Branch
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE4
Conditions: Coronary Artery Disease
Keywords: Coronary Artery Bypass
Off-Pump
Saline Solution
Hypertonic
Lead sponsor: Hospital Pitangueiras
Sponsor class: OTHER
First posted: 2011-11-02
Enrollment: 20
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This is a comparison between Hypertonic versus isotonic solution in a double blind randomized trial for off pump Coronary Artery Bypass Graft (CABG) surgery targeting the left marginal branch.

Hypertonic solution should provide better tolerance for heart mobilization with less volume expansion and less drugs.


Eligibility criteria: Inclusion Criteria:

* Off pump CABG targeting the left marginal branch

Exclusion Criteria:

* On pump surgery

Primary outcomes:
measure: Use of vasoactive drugs in left marginal branch off pump CABG surgery
timeFrame: time related to left branch coronary anastomosis for drug need.
Secondary outcomes:
measure: Fluid balance
timeFrame: Operative period and first operative day
Other outcomes:
Locations:
city: Jundiai
country: Brazil
facility: Hospital Pitangueiras
state: Sao Paulo
Study officials:
affiliation: Hospital Pitangueiras
name: ROBERTO R Silva, MD PHD
role: PRINCIPAL_INVESTIGATOR
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