Clinical trial NCT03967431: Effects of Narrative Enhancement and Cognitive Therapy (NECT) on Self-stigma in Patients With Schizophrenia
Official title: Effects of Narrative Enhancement and Cognitive Therapy (NECT) on Self-stigma in Patients With Schizophrenia: A Randomized Controlled Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Schizophrenia
Lead sponsor: National Yang Ming Chiao Tung University
Sponsor class: OTHER
First posted: 2019-05-30
Enrollment: 86
Sex: ALL
Minimum age (years): 20
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The participants were divided into experimental and control groups through block randomization.
Primary purpose: OTHER

Brief summary: This study aims to explore the effect of narrative enhancement and cognitive therapy in improving self-stigma, self-esteem, depression and hope of patients with chronic schizophrenia.

Detailed description: 86 participants with chronic schizophrenia in two different hospitals in northern Taiwan were recruited in this study. All participants were randomized into experimental and control groups through block randomization. After randomization, the participants in control group received routine care and the others in experimental group received Narrative Enhancement and Cognitive Therapy(NECT) which contains 20 times group meetings. The research tools include demographic data, the Internalized Stigma of Mental Illness Scale (ISMIS), the Discrimination and Stigma Scale (DISC), Rosenberg self-Esteem scale (RSES), Beck Depression Inventory (BDI-II) and Herth Hope Index (HHI). The questionnaires were collected for three times, including before the intervention, 12 weeks after intervention, and after the end of intervention. The collected data were analyzed by IBM SPSS 24.0 statistical software. The descriptive statistics include mean, standard deviation, minimum, maximum, frequency distribution, and percentages; the Generalized estimating equations (GEE) were used to explore the effect of Narrative Enhancement and Cognitive Therapy on self-stigma, self-esteem, depressive symptoms and hope in patients with schizophrenia after controlling demographic data.

Eligibility criteria: Inclusion Criteria:

* People with Schizophrenia for more than two years.
* The age is between 20(included) and 64(included).
* Can communicate with Mandarin or Taiwanese.
* The score of the Mini-Mental State Examination (MMSE) is above 24(included).
* The score of the Positive and Negative Syndrome Scale(PANSS) is below 60(included).
* People are willing to participate in this study, can read and know the consent and can sign on the consent by their own.

Exclusion Criteria:

* Exclude people with a personality disorder, brain injury, cognitive impairment, Intellectual Developmental Disorder or substance use disorder.
* people who are not willing to sign the consent.
* people can not read.
* people can not communicate with Mandarin or Taiwanese.

Primary outcomes:
measure: The Internalized Stigma of Mental Illness Scale (ISMIS)
timeFrame: For two groups at baseline(T0), at 12th week(T1) and at 20th week(T2)
measure: The Discrimination and Stigma Scale
timeFrame: For two groups at baseline(T0), at 12th week(T1) and at 20th week(T2)
Secondary outcomes:
measure: Beck Depression Inventory (BDI-II)
timeFrame: For two groups at baseline(T0), at 12th week(T1) and at 20th week(T2)
measure: Herth Hope Index (HHI)
timeFrame: For two groups at baseline(T0), at 12th week(T1) and at 20th week(T2)
measure: Rosenberg self-esteem scale
timeFrame: For two groups at baseline(T0), at 12th week(T1) and at 20th week(T2)
Other outcomes:
Locations:
city: Taipei City
country: Taiwan
facility: National Yang-Ming University
Study officials:
affiliation: National Yang Ming Chiao Tung University
name: Chiu-Yueh Yang, Ph.D.
role: STUDY_CHAIR
References: