Clinical trial NCT06790017: Hemoglobin-to-red Blood Cell Distribution Width Ratio and Hypothermia for Elderly Patient
Official title: Temperature Measurement for Transurethral Prostatectomy Surgery in Elderly Patient
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Transurethral Resection of Prostate Syndrome
Elderly (People Aged 65 or More)
General Anesthetic
Keywords: elderly
hypothermia
Lead sponsor: Ankara Etlik City Hospital
Sponsor class: OTHER_GOV
First posted: 2025-01-23
Enrollment: 60
Sex: MALE
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Etlik City Hospital, Urology Operating Rooms

Brief summary: As individuals age, they often enter a phase of increased "frailty." Elderly and frail patients represent a population that requires heightened sensitivity and close monitoring during surgical procedures. This study aims to investigate the relationship between the Hemoglobin-to-Red Blood Cell Distribution Width (Hb/RDW) ratio and perioperative hypothermia in elderly patients undergoing transurethral prostatectomy. This is an observational study. Preoperative blood test results and intraoperative body temperature measurements of the patients will be recorded in our data forms.


Eligibility criteria: Inclusion Criteria:

* Patients who provided informed consent.
* Patients scheduled for transurethral prostatectomy surgery.
* Patients classified as ASA-PS 1, 2, or 3.
* Male patients aged 65 years or older.
* Patients undergoing elective surgery.
* Patients receiving general anesthesia.

Exclusion Criteria:

* Patients who did not provide informed consent.
* Patients undergoing emergency surgery.
* Patients with conditions that disrupt thermoregulation (e.g., intracranial mass, peripheral vascular diseases, sepsis).
* Patients with a body temperature of \<34℃ or \>38℃ upon arrival at the preoperative waiting room.
* Patients who used heating methods other than the routine cotton cover in the preoperative waiting room.
* Patients who received additional heating methods other than the routinely applied intraoperative hot air blower drapes.
* Patients undergoing surgery under any type of anesthesia other than general anesthesia.
* Patients who were taken out of the operating room while intubated.

Primary outcomes:
measure: Perioperative Hypothermia
timeFrame: 1 hour before anesthesia and intraoperative
Secondary outcomes:
measure: Frailty
timeFrame: preoperative
measure: Red blood cell distribution width
timeFrame: 1 hour before anesthesia and intraoperative
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Etlik City Hospital
Study officials:
affiliation: Ankara Etlik City Hospital
name: Gokcen KULTUROGLU
role: PRINCIPAL_INVESTIGATOR
References:
citation: Zhu M, Wei C, Yang X, Huang Y, Xu Y, Xiong Z. Lower haemoglobin-to-red blood cell distribution width ratio is independently associated with frailty in community-dwelling older adults: a cross-sectional study. BMJ Open. 2023 Jul 9;13(7):e069141. doi: 10.1136/bmjopen-2022-069141.
citation: Qu J, Zhou T, Xue M, Sun H, Shen Y, Chen Y, Tang L, Qian L, You J, Yang R, Liu Y. Correlation Analysis of Hemoglobin-to-Red Blood Cell Distribution Width Ratio and Frailty in Elderly Patients With Coronary Heart Disease. Front Cardiovasc Med. 2021 Aug 27;8:728800. doi: 10.3389/fcvm.2021.728800. eCollection 2021.