Clinical trial NCT04947475: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community
Official title: Project MATLINK: Development and Evaluation of a Screening, Brief Intervention, & Referral to Treatment (SBIRT) Program for Opioid Dependent Prisoners and Probationers Transitioning to the Community
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Opioid-use Disorder
HIV Infections
Tuberculosis
Hepatitis C
Hepatitis B
Depression
Syphilis
Keywords: HIV
OUD
Methadone
HCV
HBV
TB
Depression
Syphilis
Lead sponsor: Yale University
Sponsor class: OTHER
Collaborators: name: Ukrainian Institute on Public Health Policy
name: AFEW Kyrgyzstan
name: AFI - Act For Involvement
name: National Institute on Drug Abuse (NIDA)
First posted: 2021-07-01
Enrollment: 835
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The purpose of this study is to evaluate the efficacy a Screening, Brief Intervention, and Referral to Treatment (SBIRT) program for linking opioid dependent individuals currently incarcerated or in probation in Moldova, Kyrgyzstan, and Ukraine to opioid substitution therapy in the community after release or during their probation period.


Eligibility criteria: Inclusion Criteria:

1. 18 years of age or older
2. Within 180 days of release or possible release (eligible for parole) to the community, but greater than 7 days to release to the community OR currently in probation.
3. FOR THOSE IN PRISON: Relocating to a location within 30 km (approximately 60-minute commute) of the referred Narcology center. Each participant will be asked the address he/she is planning to reside under that will be immediately checked on the map to determine the travel time. A participant then will be asked if he/she would be willing to travel the distance to a particular OAT site. If a person does not meet this inclusion criterion, he/she will be referred to a local harm reduction center.
4. Meets ICD-10 screening criteria for pre-incarceration opioid dependence

   FOR THOSE IN PROBATION:
5. Living within 30 km of an OAT delivery site
6. Not having received OAT in the last 15 days.
7. Positive for OUD

Exclusion Criteria:

1. Pregnant or may become pregnant
2. FOR THOSE IN PRISON: Will be released from prison in 7 days or less.

Primary outcomes:
measure: Enrollment on OAT
timeFrame: 12 months
Secondary outcomes:
measure: OAT Knowledge
timeFrame: 6 month
measure: OAT Attitudes
timeFrame: 6 months
measure: Interest in OAT
timeFrame: 6 months
measure: OAT Difficulty
timeFrame: 6 months
measure: OAT Importance
timeFrame: 6 months
Other outcomes:
Locations:
city: Bishkek
country: Kyrgyzstan
facility: AIDS Foundation East-West
city: Chisinau
country: Moldova, Republic of
facility: AFI - Act for Involvement
city: Kyiv
country: Ukraine
facility: Ukrainian Institute for Public Health Policy
Study officials:
affiliation: Yale University
name: Frederick L Altice, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: AIDS Foundation East-West
name: Natalya Shumskaya
role: STUDY_DIRECTOR
affiliation: Ukrainian Institute for Public Health Policy
name: Nataliia Saishuk
role: STUDY_DIRECTOR
affiliation: AFI - Act For Involvement
name: Svetlana Doltu
role: STUDY_DIRECTOR
References: