Clinical trial NCT03099434: Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media
Official title: Expanding Live Donor Kidney Transplantation Through Advocacy Training and Social Media
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Kidney Failure
Kidney Diseases
Keywords: Live Donor Transplant, Social Media, Education, Advocacy, Live Donor
Lead sponsor: Johns Hopkins University
Sponsor class: OTHER
Collaborators: name: University of Alabama at Birmingham
name: Northwestern University
name: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
First posted: 2017-04-04
Enrollment: 775
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Intervention model description: Patients will be randomly assigned to one of the 3 arms, where arm 1 is two interventions combined (LDC program + Facebook app), arm 2 is one intervention (Facebook app), and arm 3 is the control group (standard-of-care).
Primary purpose: OTHER

Brief summary: This pilot study will be a clinical trial to test the feasibility and effectiveness of an educational intervention and a mobile health intervention in adults with end stage renal disease (ESRD) who have not yet identified a potential live donor.

Detailed description: Transplant candidates are hesitant to discuss their illness and the difficulties associated with dialysis, and are therefore reluctant to pursue live donor kidney transplant (LDKT). The investigators will conduct a prospective 3-arm randomized controlled trial with two novel interventions to increase live donation. Arm 1 includes LDC program and the Facebook app, Arm 2 includes just the Facebook app, and Arm 3 includes standard of care. The investigators primary objective is to demonstrate the the effectiveness of these interventions in increasing live donor transplantation rates for candidates with no prior potential live donor.

Eligibility criteria: Inclusion Criteria:

* Kidney transplant candidates aged≥18 added to the waitlist in the last year with no potential live donors are eligible.
* If there is an individual willing to donate, but the candidate is unwilling to consider this option or this particular individual, the candidate is eligible for the trial and may still benefit from identification of new donors or increased comfort accepting donation from others.
* Participants at Johns Hopkins University or University of Alabama must speak English. Participants at Northwestern University must speak English or Spanish.

Exclusion Criteria:

* Candidates with live donors currently under evaluation for donation will be excluded.
* Those with a previous kidney transplant will be excluded

Primary outcomes:
measure: Live donor kidney transplantation
timeFrame: within 1 year of enrollment
Secondary outcomes:
measure: Live Donor Inquiries
timeFrame: within 1 year of enrollment
measure: knowledge of live donation
timeFrame: within 6 months of enrollment
measure: comfort initiating conversations
timeFrame: within 6 months of enrollment
Other outcomes:
Locations:
city: Evanston
country: United States
facility: Northwestern University
state: Illinois
city: Baltimore
country: United States
facility: Johns Hopkins University
state: Maryland
Study officials:
affiliation: Johns Hopkins University
name: Andrew Cameron, MD PhD
role: PRINCIPAL_INVESTIGATOR
References: