Clinical trial NCT06176586: Mat Pilates Exercise Program in Patients With Axial Psoriatic Arthritis
Official title: Investigating the Effects of Mat Pilates Exercises in Patients With Axial Psoriatic Arthritis
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Psoriatic Arthritis
Keywords: Pilates Exercise
Arthritis
Spine Mobility
Lead sponsor: Izmir Katip Celebi University
Sponsor class: OTHER
First posted: 2023-12-19
Enrollment: 48
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study is to investigate the effectiveness of mat Pilates exercises on spinal mobility, spinal muscle endurance, disease activity, fatigue, emotional well-being, physical performance, and overall quality of life in Psoriatic Arthritis (PsA) patients with axial involvement.

Detailed description: Psoriasis is a chronic inflammatory skin disease commonly accompanied by joint involvement known as psoriatic arthritis (PsA) \[1\]. PsA is a subgroup of spondyloarthritis and is characterized by peripheral arthritis, dactylitis, enthesitis and spondylitis. Axial involvement, which occurs in approximately 40% of PsA patients may affect the entire spine, particularly the sacroiliac joint, leading to reduced cervical rotation, lateral flexion and anterior flexion of the spine \[2,3\]. Exercise interventions in PsA primarily aim to relieve pain, improve mobility and enhance functional capacity \[4\]. Mat Pilates exercises have been demonstrated as a safe and beneficial intervention in various rheumatic diseases, exhibiting significant improvements in functional status, fatigue, disease activity, pain, and overall quality of life \[5-7\]. Additionally, Pilates has been reported as effective in maintaining and enhancing spinal mobility \[8,9\]. However, despite these favorable outcomes, the efficacy of Pilates exercises in PsA remains unexplored.

The aim of this study is to investigate the effectiveness of mat pilates exercises in psoriatic arthritis patients with axial involvement.

Eligibility criteria: Inclusion Criteria:

* Being classified as PsA according to CASPAR Classification Criteria
* Being between the ages of 18-65
* Volunteering to participate in the study

Exclusion Criteria:

* Any additional systemic disease other than PsA
* Any other condition that may prevent participation/continuation of the exercise program or completion of the assessments
* Regular exercise habits (following a structured exercise program at least 3 days a week)
* Being included in a physiotherapy and rehabilitation program within the last 6 months

Primary outcomes:
measure: Change in Physical Performance
timeFrame: At baseline and 12 weeks later
Secondary outcomes:
measure: Change in Functional Status
timeFrame: At baseline and 12 weeks later
measure: Change in Trunk Muscle Endurance
timeFrame: At baseline and 12 weeks later
measure: Change in Spinal Mobility
timeFrame: At baseline and 12 weeks later
measure: Chance in Disease Activity
timeFrame: At baseline and 12 weeks later
measure: Change in Fatigue
timeFrame: At baseline and 12 weeks later
measure: Change in Emotional Status
timeFrame: At baseline and 12 weeks later
measure: Change in Quality of Life
timeFrame: At baseline and 12 weeks later
Other outcomes:
Locations:
city: İzmir
country: Turkey
facility: Izmir Katip Celebi University
Study officials:
affiliation: Izmir Katip Celebi University
name: Deniz Bayraktar, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Parisi R, Symmons DP, Griffiths CE, Ashcroft DM; Identification and Management of Psoriasis and Associated ComorbidiTy (IMPACT) project team. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol. 2013 Feb;133(2):377-85. doi: 10.1038/jid.2012.339. Epub 2012 Sep 27.
citation: Ogdie A, Weiss P. The Epidemiology of Psoriatic Arthritis. Rheum Dis Clin North Am. 2015 Nov;41(4):545-68. doi: 10.1016/j.rdc.2015.07.001. Epub 2015 Sep 11.
citation: Gladman DD, Antoni C, Mease P, Clegg DO, Nash P. Psoriatic arthritis: epidemiology, clinical features, course, and outcome. Ann Rheum Dis. 2005 Mar;64 Suppl 2(Suppl 2):ii14-7. doi: 10.1136/ard.2004.032482.
citation: Chimenti MS, Triggianese P, Conigliaro P, Santoro M, Lucchetti R, Perricone R. Self-reported adherence to a home-based exercise program among patients affected by psoriatic arthritis with minimal disease activity. Drug Dev Res. 2014 Nov;75 Suppl 1:S57-9. doi: 10.1002/ddr.21197.
citation: Altan L, Korkmaz N, Dizdar M, Yurtkuran M. Effect of Pilates training on people with ankylosing spondylitis. Rheumatol Int. 2012 Jul;32(7):2093-9. doi: 10.1007/s00296-011-1932-9. Epub 2011 Apr 17.
citation: Caglayan BC, Keskin A, Gur Kabul E, Basakci Calik B, Bas Aslan U, Karasu U. Effects of clinical Pilates exercises in individuals with fibromyalgia: A randomized controlled trial. Eur J Rheumatol. 2021 Jul;8(3):150-155. doi: 10.5152/eurjrheum.2020.20037.
citation: Acar Y, Ilcin N, Gurpinar B, Can G. The effects of clinical pilates training on disease-specific indices, core stability, and balance in patients with ankylosing spondylitis. J Bodyw Mov Ther. 2023 Jan;33:69-75. doi: 10.1016/j.jbmt.2022.09.010. Epub 2022 Sep 23.
citation: Oksuz S, Unal E. Comparison of the effects of aerobic training alone versus aerobic training combined with clinical Pilates exercises on the functional and psychosocial status of patients with ankylosing spondylitis: A randomized controlled trial. Physiother Theory Pract. 2023 Jan;39(1):61-71. doi: 10.1080/09593985.2021.2005199. Epub 2021 Nov 18.