Clinical trial NCT04508465: Persistent Postoperative Pain After Major Emergency Abdominal Surgery
Official title: Persistent Postoperative Pain After Major Emergency Abdominal Surgery
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Chronic Postoperative Pain
Lead sponsor: Zealand University Hospital
Sponsor class: OTHER
First posted: 2020-08-11
Enrollment: 110
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who have undergone major emergency abdominal surgery at the department of abdominal surgery at Zealand University Hospital Køge

Brief summary: Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake, reduced pulmonary capacity and increased risk of complications and length of hospitalization. The literature does not supply much information on short- or longer-term outcomes of pain treatment for emergency surgery. The investigators know that for planned surgery in general around 10-50 percentage suffer from persistent postoperative pain. It is therefore important to follow-up on the longer-term outcomes after the standardized analgesic pain treatment. Based on a predefined patient group called OMEGA (Optimizing Major EMergency Abdominal surgery) the investigators hypothesize that OMEGA patients will present a significant incidence rate of patients with persistent postoperative pain and/or continued opioid/non-opioid usage. Therefore this study is to investigate the incidence of prolonged postoperative pain and opioid/non-opioid consumption in OMEGA patients at 3 month after major emergency abdominal surgery.


Eligibility criteria: Inclusion Criteria:

* OMEGA patients (patients who have undergone major emergency abdominal surgery including the stomach, small or large bowel, or rectum for conditions such as perforation, ischemia, abdominal abscess, bleeding or obstruction)
* Age 18 or more
* Surgery performed within 72 hours of an acute admission or as an acute re-operation

Exclusion Criteria:

* Elective laparoscopy
* Diagnostic laparotomy/laparoscopy where no subsequent procedure is performed
* Non-elective hernia repair without bowel resection
* Admission or transfer to an intensive care unit

Primary outcomes:
measure: Pain Mobilization
timeFrame: Data is collected 3 months postoperative
measure: Opioids
timeFrame: Data is collected 3 months postoperative
Secondary outcomes:
measure: Pain Rest
timeFrame: Data is collected 3 months postoperative
measure: Non-opiod Analgesic
timeFrame: Data is collected 3 months postoperative
measure: Barthel-20 Index
timeFrame: Data is collected 3 months postoperative
measure: EuroQol-5
timeFrame: Data is collected 3 months postoperative
measure: Montreal Cognitive Assessment test (Mini-MoCA)
timeFrame: Data is collected 3 months postoperative
Other outcomes:
Locations:
city: Køge
country: Denmark
facility: Zealand University Hospital, Department of Anaesthesiology
Study officials:
References: