Clinical trial NCT01327196: Cognitive Impairment and Cardiovascular Risk in Older
Official title: Detection of Mild Cognitive Impairment in People Older Than 65 Years of Age and Its Relationship to Cardiovascular Risk Factors (DECRIVAM)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cognitive Impairment
Cardiovascular Risk Factor
Keywords: dementia
cardiovascular risk
elderly
aging
older 65-100 years
Lead sponsor: Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Sponsor class: OTHER
Collaborators: name: Grupo de Investigación de Atención Primaria de Castilla y León
First posted: 2011-04-01
Enrollment: 327
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: It will depart from a reference population of 420 people older than 65 years living in the municipality of Salamanca

Brief summary: The objective of this project is to study cognitive yields in people of the town of Salamanca over 65, with particular emphasis on the acquisition of the initial symptoms of cognitive impairment in order to detect mild cognitive impairment and study the relationship between the clinical situation and cardiovascular risk factors. It will depart from a reference population of 420 people older than 65 years living in the municipality of Salamanca which took part in a survey prior to partner health needs of the elderly of 65 years in the municipality of Salamanca. This was a stratified sampling as stratum considering the area of health. The results of this study are expected to evidence the extent of the problem of cognitive decline in the population over 65 years. It is also expected to determine the relationship between the co-morbidity in this problem and specific factors of cardiovascular risk in this group of population.

Detailed description: A random sample population, the information obtained has a validity superior to other studies in which the sample has not followed very strict criteria of selection.

Protocol for measurement:

* variable demographic partner
* vascular risk factors
* co-morbidity
* functional level for the activities of daily life
* cognitive performance in attention, memory, language, praxias, gnosias (abbreviated neuropsychological battery)

Through a battery short neuropsychological specially adapted for the study of older people will carry out a study of the cognitive performance in people older than 65 years of age and will try to establish how much influence the controlled variables of cardiovascular risk.

Eligibility criteria: Inclusion Criteria:

* lives in the municipality of Salamanca
* over 65 years of age

Primary outcomes:
measure: Prevalence of risk factors cardiovascular
timeFrame: Prevalence of risk factors cardiovascular
Secondary outcomes:
measure: neuropsychological assessment
timeFrame: neuropsychological assessment
Other outcomes:
measure: neuropsychological assessment
timeFrame: neuropsychological assessment
Locations:
city: Salamanca
country: Spain
facility: Fundacion INFOSALUD
Study officials:
affiliation: Fundacion INFOSALUD
name: MºVictoria Perea-Bartolome, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Fundacion INFOSALUD
name: Emiliano Rodriguez-Sanchez, MD
role: STUDY_DIRECTOR
References:
citation: Perea-Bartolome MV, Garcia-Garcia R, Ladera-Fernandez V, Mora-Simon S, Patino-Alonso MC, Almanza-Guerra TJ, Agudo-Conde C, Muriel-Diez MP, Rodriguez-Sanchez E. Detection of mild cognitive impairment in people older than 65 years of age and its relationship to cardiovascular risk factors (DECRIVAM). BMC Public Health. 2011 Jun 27;11:504. doi: 10.1186/1471-2458-11-504.