Clinical trial NCT07013786: Correlation Between Motor Control Dysfunction and Radiographic Parameter in Non Specific Chronic Low Back Pain
Official title: Correlation Between Motor Control Dysfunction and Radiographic Parameter in Non Specific Chronic Low Back Pain
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Chronic Non Specific Low Back Pain
Keywords: Lumbar motor control dysfunction
Lumbopelvic parameters
Radiographic alignment
Transverse abdominis
Multifidus
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-06-10
Enrollment: 64
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients aged 20-40 years diagnosed with non-specific chronic low back pain (NSCLBP), recruited from the outpatient physical therapy clinic of Cairo University. Participants will be screened based on clinical and radiographic criteria to ensure eligibility and safety.

Brief summary: This study aims to investigate the relationship between motor control dysfunction (MCD) and radiographic parameters in non-specific chronic low back pain (NSCLBP). Participants will undergo specific clinical motor control tests and lumbar spine X-rays to evaluate the alignment and coordination of spinal and pelvic structures. Understanding this relationship may help improve rehabilitation strategies and reduce pain in affected individuals.

Detailed description: Non-specific chronic low back pain (NSCLBP) is a common musculoskeletal condition associated with impaired neuromuscular coordination and motor control dysfunction (MCD). This study seeks to determine the correlation between MCD and radiographic parameters including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), and lumbar lordotic angle (LLA).

A total of 64 participants aged 20-40 with NSCLBP will be evaluated at the Faculty of Physical Therapy, Cairo University. Motor control will be assessed using a pressure biofeedback unit in two positions (crock lying and prone) via the Abdominal Draw-in Maneuver (ADIM). Radiographic measurements will be taken using lateral lumbar spine X-rays in standing posture.

The aim is to identify whether poor activation of deep stabilizing muscles (Transverse Abdominus and Multifidus) correlates with abnormal pelvic alignment and altered spinal curvature. Outcomes may support more effective personalized rehabilitation protocols targeting neuromuscular control to improve spine-pelvis function in NSCLBP patients.

Statistical analysis will include Pearson correlation to test for associations between motor control test performance and radiographic angle values.

Eligibility criteria: Inclusion Criteria:

* . Patients diagnosed with non-specific chronic low back pain (NSCLBP) for more than 3 months

  * Age between 20 and 40 years
  * Both males and females
  * Body mass index (BMI) between 18.5 and 29.9
  * No physical therapy or medical treatment during the last 3 months
  * Able and willing to provide informed consent

Exclusion Criteria:

* • Patients with specific causes of low back pain (e.g., disc herniation, fractures, tumors, infections)

  * History of spinal or lower limb surgery or injury
  * Radiculopathy or neurological disorders affecting motor control
  * Diagnosed spinal deformities (e.g., scoliosis, spondyloarthropathy, ankylosing spondylitis)
  * Contraindications to X-ray (e.g., pregnancy)
  * Patients currently undergoing physical therapy or medical intervention

Primary outcomes:
measure: Lumbar Lordotic Angle
timeFrame: At baseline (during initial assessment visit)
measure: Pelvic Incidence Angle
timeFrame: At baseline (during initial assessment visit)
measure: Pelvic Tilt Angle
timeFrame: At baseline (during initial assessment visit)
measure: Sacral Slope Angle
timeFrame: At baseline (during initial assessment visit)
measure: Lumbar Motor Control Assessment via Pressure Biofeedback during ADIM
timeFrame: At baseline (during initial assessment visit)
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Cairo university- Faculty of physical therapy
name: Enas Fawzy Youssef, Phd,MSc,PSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Cairo university- faculty of medicine,department of radiology
name: Nevien Ezzat Elliethy, Phd,MSc,PSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Cairo university- Faculty of physical therapy
name: Tasneem Ehab Mohammad, Phd,MSc,PSc
role: PRINCIPAL_INVESTIGATOR
References:
citation: Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LC, Ostelo RW, Macedo LG. Motor control exercise for chronic non-specific low-back pain. Cochrane Database Syst Rev. 2016 Jan 8;2016(1):CD012004. doi: 10.1002/14651858.CD012004.