Clinical trial NCT05276986: Effects of Delayed Muscle Pain on Respiratory Muscle Function
Official title: Effects of Delayed Muscle Pain on Respiratory Muscle Function
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Muscle Soreness
Exercise
Respiratory Muscles
Respiratory Function Tests
Keywords: Muscle Soreness
Exercise
Respiratory Muscles
Respiratory Function Tests
Lead sponsor: Ankara Yildirim Beyazıt University
Sponsor class: OTHER
First posted: 2022-03-14
Enrollment: 24
Sex: ALL
Minimum age (years): 18
Maximum age (years): 24
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: 24 healthy university students (n=11 female, n=13 male) with a mean age of 21±2 years included the study.
Primary purpose: SCREENING

Brief summary: The aim of the study was to determine whether delayed-onset muscle soreness (DOMS) in trunk muscles has an effect on respiratory function parameters, respiratory muscle strength, respiratory muscle endurance, and exercise capacity.

Detailed description: In 24 healthy university students was induced for the trunk muscles with a load equals to 80% of the maximum repetitive voluntary contraction. Pulmonary function parameters, respiratory muscle strength and endurance, exercise capacity, pain, fatigue, and dyspnea perception severity were recorded before DOMS and at the 24th and 48th hours after DOMS.

After DOMS, there is a decrease in respiratory performance values and exercise capacity of healthy individuals and athletes. Therefore, it should be taken into account that delayed muscle soreness before the competition may affect performance. It may be beneficial to take precautions for delayed muscle pain while creating training and exercise programs, and to create treatment programs in case of the emergence of DOMS.

Eligibility criteria: Inclusion Criteria:

* Being a healthy individual between the ages of 18-25
* Not having a regular exercise habit
* No infection until at least 3 weeks before the study

Exclusion Criteria:

* Lung disease
* Cardiovascular disease
* Neurological disease
* Orthopedic disease

Primary outcomes:
measure: Pulmonary Function Tests (FVC)
timeFrame: Pulmonary function test measurements were made in all individuals at baseline.
measure: Pulmonary Function Tests (FEV1)
timeFrame: Pulmonary function test measurements were made in all individuals at baseline.
measure: Pulmonary Function Tests (FEF25%-75%)
timeFrame: Pulmonary function test measurements were made in all individuals at baseline.
measure: Pulmonary Function Tests (VC)
timeFrame: Pulmonary function test measurements were made in all individuals at baseline.
measure: Pulmonary Function Tests (FVC)
timeFrame: Pulmonary function test measurements were made in all individuals at the 24th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (FEV1)
timeFrame: Pulmonary function test measurements were made in all individuals at the 24th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (FEF25%-75%)
timeFrame: Pulmonary function test measurements were made in all individuals at the 24th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (VC)
timeFrame: Pulmonary function test measurements were made in all individuals at the 24th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (FVC)
timeFrame: Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (FEV1)
timeFrame: Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (FEF25%-75%)
timeFrame: Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.
measure: Pulmonary Function Tests (VC)
timeFrame: Pulmonary function test measurements were made in all individuals at the 48th hours after the trunk-oriented DOMS.
measure: Respiratory Muscle Strength Measurement
timeFrame: This test was carried out at baseline.
measure: Respiratory Muscle Strength Measurement
timeFrame: This test was carried out at the 24th after DOMS.
measure: Respiratory Muscle Strength Measurement
timeFrame: This test was carried out at 48th hours after DOMS.
measure: Respiratory Muscle Endurance Test
timeFrame: This test was performed at baseline.
measure: Respiratory Muscle Endurance Test
timeFrame: This test was performed at 24 hours after DOMS.
measure: Respiratory Muscle Endurance Test
timeFrame: This test was performed at 48 hours after DOMS.
measure: Exercise Capacity
timeFrame: This test was carried out at baseline.
measure: Exercise Capacity
timeFrame: This test was carried out at the 24th hours after DOMS.
measure: Exercise Capacity
timeFrame: This test was carried out at 48th hours after DOMS.
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Ankara Yildirim Beyazit University,Faculty of Health Sciences, Physiotherapy and Rehabilitation Department
city: Ankara
country: Turkey
facility: Faculty of Health Sciences, Departmant of Physiotherapy and Rehabilitation, Baskent University
Study officials:
affiliation: Cyprus International University, School of Physical Education and Sports
name: Sema Ozden
role: PRINCIPAL_INVESTIGATOR
affiliation: Cyprus International University, Faculty of Health Sciences,Department of Physiotherapy and Rehabilitation
name: Ozge Ozalp
role: STUDY_DIRECTOR
affiliation: Ankara Yildirim Beyazit University,Faculty of Health Sciences, Physiotherapy and Rehabilitation Department
name: Rabia Tugba Kilic
role: STUDY_DIRECTOR
affiliation: Baskent University, Physiotherapy and Rehabilitation Department
name: Hayri Baran Yosmaoglu
role: STUDY_CHAIR
References:
citation: Benditt JO. Respiratory Care of Patients With Neuromuscular Disease. Respir Care. 2019 Jun;64(6):679-688. doi: 10.4187/respcare.06827.
citation: Lieber RL, Friden J. Morphologic and mechanical basis of delayed-onset muscle soreness. J Am Acad Orthop Surg. 2002 Jan-Feb;10(1):67-73.
citation: Imtiyaz S, Veqar Z, Shareef MY. To Compare the Effect of Vibration Therapy and Massage in Prevention of Delayed Onset Muscle Soreness (DOMS). J Clin Diagn Res. 2014 Jan;8(1):133-6. doi: 10.7860/JCDR/2014/7294.3971. Epub 2014 Jan 12.
citation: Cheung K, Hume P, Maxwell L. Delayed onset muscle soreness : treatment strategies and performance factors. Sports Med. 2003;33(2):145-64. doi: 10.2165/00007256-200333020-00005.
citation: Jamurtas AZ, Theocharis V, Tofas T, Tsiokanos A, Yfanti C, Paschalis V, Koutedakis Y, Nosaka K. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. Eur J Appl Physiol. 2005 Oct;95(2-3):179-85. doi: 10.1007/s00421-005-1345-0. Epub 2005 Jul 9.
citation: Hotta N, Yamamoto K, Katayama K, Ishida K. The respiratory response to passive and active arm movements is enhanced in delayed onset muscle soreness. Eur J Appl Physiol. 2009 Feb;105(3):483-91. doi: 10.1007/s00421-008-0926-0. Epub 2008 Nov 15.
citation: Black LF, Hyatt RE. Maximal respiratory pressures: normal values and relationship to age and sex. Am Rev Respir Dis. 1969 May;99(5):696-702. doi: 10.1164/arrd.1969.99.5.696. No abstract available.