Clinical trial NCT05133375: Hemodynamic Changes of Tracheal Intubation With McCoy and Macintosh Laryngoscopes
Official title: Comparison of Hemodynamic Changes of Tracheal Intubation With McCoy and Macintosh Laryngoscopes
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hemodynamic Rebound
Lead sponsor: CMH Jhelum
Sponsor class: OTHER
First posted: 2021-11-24
Enrollment: 272
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: A total of 272 patients were randomly allocated into two groups, Patients in group A were treated with Macintosh laryngoscope and in groups B with McCoy laryngoscope was used for endotracheal intubation. Pulse and systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3minutes after intubation. All this information was recorded on a Pro forma.

Detailed description: After taking approval from hospital ethical committee, 272 patients who reported to Operation Theatre of CMH, Jhelum were selected for the study. Informed consent was obtained and patient demographic information (name, age, contact) was recorded. Patients were randomly divided in two equal groups by using lottery method. GROUP A: Where Macintosh laryngoscope was used for endotracheal intubation. GROUP B: Where McCoy laryngoscope was used for endotracheal intubation.

Before reporting to Operation theatre a detailed pre anesthesia assessment was done in all patients, all necessary laboratory investigations were collected. On OT table pulse and systolic blood pressure was checked by non-invasive method. 18G cannula was passed and ECG was attached. A pillow was placed under the head to obtain classical sniffing position for intubation. All the patients were pre medicated with injection midazolam 0.08mg/kg, injection nalbuphine 0.1 mg/kg, injection dexamethasone 0.08mg/kg and injection metoclopramide 0.1 mg/kg. Pre oxygenation was done with 100% oxygen for 3 mins. Induction was done with injection propofol2 mg/kg, muscle relaxation achieved with injection atracurium 0.5mg/kg. Laryngoscopy was started after 3 minutes by a qualified anesthetist. Pulse and systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3minutes after intubation. All this information was recorded on a Proforma.

Eligibility criteria: Inclusion Criteria:

* Both Male and Female
* Age between 18 to 70
* ASA I and II males and females.
* Malampatti I and II.
* Hemodynamically stable, no known ischemic heart disease and no history of hypertension.
* Nil per oral for at least 6 hours.

Exclusion Criteria:

* Non consenting patient.
* ASA III, IV or V patient.
* Malampati III or IV.
* Cervical instability
* Thyromental distance of less than 6cm, inter incisor distance of less than 3cm.
* Known case of hypertension and ischemic heart disease.
* Pregnant female.
* Body mass index of more than 30.
* Patients of oropharyngeal surgery.
* Unable to Intubate in less than 1 minute.

Primary outcomes:
measure: Effect on the pulse of intubation with Macintosh and McCoy laryngoscope
timeFrame: After Laryngoscopy, pulse was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation.
measure: Effect on the systolic blood pressure of intubation with Macintosh and McCoy laryngoscope
timeFrame: After Laryngoscopy, systolic blood pressure was recorded by non-invasive measures before laryngoscopy and at 30 seconds, 2 and 3 minutes after intubation
Secondary outcomes:
Other outcomes:
Locations:
city: Jhelum
country: Pakistan
facility: CMH
state: Punjab
Study officials:
affiliation: Anesthesiologist
name: Muhammad Awais Qarni
role: PRINCIPAL_INVESTIGATOR
References: