Clinical trial NCT05237830: Effectiveness of Intraoperative Cell Salvage in Aseptic Revision Total Hip Arthroplasty.
Official title: Effectiveness of Intraoperative Cell Salvage in Aseptic Revision Total Hip Arthroplasty: a Single-center Retrospective Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Revision of Total Hip Arthroplasty
Lead sponsor: University of Liege
Sponsor class: OTHER
First posted: 2022-02-14
Enrollment: 140
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Revision of arthroplasty was defined as the exchange of any component of the hip prosthesis.

Brief summary: Intraoperative cell salvage is an important measure of patient blood management but its effectiveness in patients undergoing revision total hip arthroplasty remains unclear. Over the last decade, we have used intraoperative cell salvage systematically in this group of patients. However, since the use of cell salvage has a cost and requires additional resources, we decided to retrospectively investigate its usefulness in this particular indication.


Eligibility criteria: Inclusion Criteria:

* Eligible patients were adults undergoing elective aseptic revision of hip arthroplasty at the department of orthopedic surgery of the University Hospital of Liege between 01 January 2011 and 31 December 2020.

Exclusion Criteria:

* Patients undergoing revision for infection or with local malignancies were excluded from this study.

Primary outcomes:
measure: Cell savage use
timeFrame: during the surgical procedure
Secondary outcomes:
measure: Re-infused
timeFrame: during the surgical procedure
measure: Hemoglobin
timeFrame: during the surgical procedure
measure: Allogenic Transfusion
timeFrame: 7 days
measure: Aspirated blood
timeFrame: during the surgical procedure
measure: Fluid
timeFrame: during the surgical procedure
Other outcomes:
Locations:
city: Liège
country: Belgium
facility: CHU de Liège
Study officials:
References:
citation: Greenky M, Shaner J, Rasouli MR, Han SB, Parvizi J, Hozack WJ. Intraoperative blood salvage in revision total hip arthroplasty: who benefits most? J Arthroplasty. 2014 Jun;29(6):1298-300. doi: 10.1016/j.arth.2013.12.009. Epub 2013 Dec 14.
citation: Palmer AJR, Lloyd TD, Gibbs VN, Shah A, Dhiman P, Booth R, Murphy MF, Taylor AH, Kendrick BJL; collaborators. The role of intra-operative cell salvage in patient blood management for revision hip arthroplasty: a prospective cohort study. Anaesthesia. 2020 Apr;75(4):479-486. doi: 10.1111/anae.14989. Epub 2020 Feb 9.
citation: Rigal JC, Riche VP, Tching-Sin M, Fronteau C, Huon JF, Cadiet J, Boukhari R, Vourc'h M, Rozec B. Cost of red blood cell transfusion; evaluation in a French academic hospital. Transfus Clin Biol. 2020 Nov;27(4):222-228. doi: 10.1016/j.tracli.2020.08.002. Epub 2020 Aug 15.
citation: Goel R, Patel EU, Cushing MM, Frank SM, Ness PM, Takemoto CM, Vasovic LV, Sheth S, Nellis ME, Shaz B, Tobian AAR. Association of Perioperative Red Blood Cell Transfusions With Venous Thromboembolism in a North American Registry. JAMA Surg. 2018 Sep 1;153(9):826-833. doi: 10.1001/jamasurg.2018.1565.
citation: Walsh TS, Palmer J, Watson D, Biggin K, Seretny M, Davidson H, Harkness M, Hay A. Multicentre cohort study of red blood cell use for revision hip arthroplasty and factors associated with greater risk of allogeneic blood transfusion. Br J Anaesth. 2012 Jan;108(1):63-71. doi: 10.1093/bja/aer326. Epub 2011 Oct 27.