Clinical trial NCT06890559: Enhancing Vaccination Uptake Through Points Redemption Based Financial Incentives and Digital Platforms: an Open-label Cluster Randomized Controlled Trial Utilizing Community Mobilization and Empowerment Strategies
Official title: Enhancing Vaccination Uptake Through Points Redemption Based Financial Incentives and Digital Platforms: an Open-label Cluster Randomized Controlled Trial Utilizing Community Mobilization and Empowerment Strategies
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Vaccination Uptake
Keywords: financial incentive
Lead sponsor: Zhejiang University
Sponsor class: OTHER
First posted: 2025-03-24
Enrollment: 5120
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The overall goal is to develop and optimize a health digital platform and points redemption-based financial incentive interventions for the promotion of non-National Immunization Program (non-NIP) vaccination uptake and related preventative behaviors in China, and formulate a low-cost, labor-saving and replicable pattern. The primary objective is to develop and optimize a digital platform-based point-redemption and financial incentive system and evaluate the effectiveness of the interventions for improving non-NIP vaccines coverage and related preventive behaviors.The main questions it aims to answer are:

H1: Participants allocated to the intervention group will demonstrate a 3% increase in vaccine doses of targeted non-NIP vaccines, including HPV vaccines, influenza vaccines, pneumonia vaccines, rotavirus vaccines, varicella vaccines, and haemophilus Influenza Type B polysaccharide conjugate (Hib) vaccines, compared to those in the control group at the 12-month follow-up.

H2: Participants allocated to the intervention group will exhibit a 5% increase in the prevalence of related preventive behaviors compared to those in the control group at the 12-month follow-up.

Researchers will compare the financial incentive intervention to the routine activities to see if the intervention works to improve the vacciantion rate of non-NIP vaccines.

Participants will:

1. Participants can automatically input their health behaviors through the digital platform, and the back-end will verify the information with data provided by the township hospitals or community health centers.
2. A QR code will be implemented at each township hospital or community health center. Participants will scan the QR code after completing vaccination or other related preventive behaviors. The digital platform will automatically record points for each completed behavior.
3. Use accumulated points to redeem gifts on the system, including household goods, electronic products, and free or discounted health services.


Eligibility criteria: Inclusion Criteria:

* Do not move from the original research and implementation site within the next year;
* Voluntarily participate in the study and sign the informed consent;
* No mental disorder or cognitive impairment, able to understand and cooperate with research requirements.

Exclusion Criteria:

* Have contraindications related to vaccination;
* The state of the body during the intervention period is not suitable for vaccination.

Primary outcomes:
measure: The number of targeted non-NIP vaccine doses per 1,000 person-years
timeFrame: one year
Secondary outcomes:
measure: Number of cervical cancer screenings, medical checkups for the elderly, and check-ups for children during the intervention period
timeFrame: one year
Other outcomes:
Locations:
Study officials:
References: