Clinical trial NCT05584839: Statistically Analysis of Carpal Tunnel Syndrome Diagnosis
Official title: A Comprehensive Statistical Analysis for the Diagnosis of Carpal Tunnel Syndrome
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Carpal Tunnel Syndrome
Diagnosis
Keywords: carpal tunnell syndrome
anthpometric
Lead sponsor: Ahi Evran University Education and Research Hospital
Sponsor class: OTHER
First posted: 2022-10-18
Enrollment: 40
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Persons aged 18-65 years who apply to outpatient clinics with symptoms of CTS

Brief summary: Trap neuropathies; They are compression neuropathies that occur as a result of peripheral nerves being compressed for various reasons along their anatomical paths. Although each nerve has areas suitable for anatomical entrapment, compression can occur at any point along the nerve. Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by compression of the median nerve at the wrist level. Its prevalence in the general population is 2.5-11%.

Although the majority of cases are idiopathic, it may also occur secondary to pathologies such as pregnancy, diabetes mellitus, thyroid dysfunction, arthritis, wrist fractures and acromegaly or occupation. The diagnosis of CTS is made clinically, but the best method for definitive diagnosis is electrophysiological examination.

Some anthropometric measurements that may be associated with CTS were made and their effect on the risk of CTS was investigated. In a study conducted by Sabry et al. in 2009, it was reported that there may be a relationship between BMI, wrist ratio (ratio of wrist depth to width) and wrist-palm ratio (ratio of wrist depth to palm length) and CTS risk. In a study by Lim et al. in 2008, it was reported that the critical value for wrist ratio was 0.70 and above. However, there were no studies reporting how many percent predictors of anthropometric measurements according to the severity of CTS.

Detailed description: The study was planned as a quantitative research. Socio-demographic information form, anthropometric measurements of hand grip strength, palm length, hand width length, wrist circumference length, Visual Analog Scale scale, EMG findings will be evaluated by hand dynamometer.

Trybus et al. Considering the study they conducted in patients with CTS in which they examined hand anthropometric measurements in CTS, it was planned to include 100 patients in the study with a power range of 80% and an effect width of 0.05.

Eligibility criteria: Inclusion Criteria:

* Admitted to outpatient clinics with symptoms of CTS
* Findings of CTS in physical examination
* CTS diagnosis was confirmed by nerve conduction study
* KTS grade mild or moderate
* He has not received physical therapy for this reason in the previous 1 year
* No steroid injection and no treatment for neuropathic pain (pregabalin, gabapentin, etc.)

Exclusion Criteria:

* - Those under the age of 18 Those with a history of previous surgery or fracture of the affected hand and wrist Those with diabetes mellitus, chronic kidney failure, gout, rheumatoid arthritis, thyroid diseases
* Pregnant Those with polyneuropathy, radiculopathy, plexopathy, thoracic outlet syndrome

Primary outcomes:
measure: Hand Grip Strength
timeFrame: 0-1 days
Secondary outcomes:
measure: Hand length
timeFrame: 0-1 days
Other outcomes:
Locations:
city: Kırşehir
country: Turkey
facility: İsmail Ceylan
state: Merkez
Study officials:
References:
citation: Calixtre LB, Oliveira AB, de Sena Rosa LR, Armijo-Olivo S, Visscher CM, Alburquerque-Sendin F. Effectiveness of mobilisation of the upper cervical region and craniocervical flexor training on orofacial pain, mandibular function and headache in women with TMD. A randomised, controlled trial. J Oral Rehabil. 2019 Feb;46(2):109-119. doi: 10.1111/joor.12733. Epub 2018 Oct 26.