Clinical trial NCT00175175: Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
Official title: Randomized Trial of Osteoporosis Intervention Strategies in Hip Fracture Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoporosis
Hip Fracture
Keywords: osteoporosis treatment
osteoporosis testing
hip fracture
quality improvement
Lead sponsor: University of Alberta
Sponsor class: OTHER
Collaborators: name: Alberta Heritage Foundation for Medical Research
name: Royal Alexandra Hospital
First posted: 2005-09-15
Enrollment: 220
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Patients with hip fractures have suffered the most devastating consequence of osteoporosis; and yet, they are rarely if ever tested or treated for the condition, even though they remain at high risk of recurrent fracture.

We hypothesize that, compared with usual care, an allied health professional-run osteoporosis service (case management) will be able to increase testing and treatment of osteoporosis in patients at high risk of fracture.

Detailed description: Patients with hip fractures have suffered the most devastating consequence of osteoporosis; and yet, they are rarely if ever tested or treated for the condition, even though they remain at high risk of recurrent fracture.

We hypothesize that, compared with usual care, an allied health professional-run osteoporosis service (case management) will be able to increase testing and treatment of osteoporosis in patients at high risk of fracture.

Eligibility criteria: Inclusion Criteria:

* hip fracture patient \> 50 years of age
* able to give consent (or proxy consent available)
* lives within health region
* no contraindications to bisphosphonate therapy

Exclusion Criteria:

* refuses to participate or consent
* dementia or delirium without a proxy consent available
* nursing home or longterm care
* pathologic fracture
* chronic glucocorticoid use
* already receiving prescription osteoporosis treatment (calcium and vitamin D do not preclude inclusion)

Primary outcomes:
measure: The proportion of patients taking bisphosphonate therapy within 6 months of hip fracture
Secondary outcomes:
measure: Proportion of patients taking prescription osteoporosis treatment at 6 months and 12 months
measure: Proportion in receipt of a BMD test at 6 months and 12 months
measure: Proportion still adherent to osteoporosis treatments at 6 months and 12 months
measure: Proportion of patients with recurrent fractures at 6 months and 12 months
measure: Cost effectiveness analyses
Other outcomes:
Locations:
city: Edmonton
country: Canada
facility: University of Alberta Hospitals
state: Alberta
Study officials:
affiliation: University of Alberta
name: Sumit R Majumdar, MD, MPH
role: PRINCIPAL_INVESTIGATOR
References:
citation: Morrish DW, Beaupre LA, Bell NR, Cinats JG, Hanley DA, Harley CH, Juby AG, Lier DA, Maksymowych WP, Majumdar SR. Facilitated bone mineral density testing versus hospital-based case management to improve osteoporosis treatment for hip fracture patients: additional results from a randomized trial. Arthritis Rheum. 2009 Feb 15;61(2):209-15. doi: 10.1002/art.24097.
citation: Majumdar SR, Lier DA, Beaupre LA, Hanley DA, Maksymowych WP, Juby AG, Bell NR, Morrish DW. Osteoporosis case manager for patients with hip fractures: results of a cost-effectiveness analysis conducted alongside a randomized trial. Arch Intern Med. 2009 Jan 12;169(1):25-31. doi: 10.1001/archinte.169.1.25.
citation: Majumdar SR, Beaupre LA, Harley CH, Hanley DA, Lier DA, Juby AG, Maksymowych WP, Cinats JG, Bell NR, Morrish DW. Use of a case manager to improve osteoporosis treatment after hip fracture: results of a randomized controlled trial. Arch Intern Med. 2007 Oct 22;167(19):2110-5. doi: 10.1001/archinte.167.19.2110.