Clinical trial NCT03443375: Exercise Periodization and Older Adults
Official title: Effects of Resistance Training Periodization on Hemodynamic, Morphofunctional and Cognitive Parameters of Robust Older Women.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Aging
Physical Activity
Sarcopenia
Cognitive Decline
Blood Pressure
Physical Disability
Keywords: Older adults
Physical function
Muscle mass
Short-term memory
Executive function
Blood Pressure
Resistance training
Exercise training
Periodization
Lead sponsor: University of Campinas, Brazil
Sponsor class: OTHER
First posted: 2018-02-23
Enrollment: 14
Sex: FEMALE
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The present study aimed at investigating the effects of two different resistance training protocols - nonperiodized (NP) and daily undulating periodization (DUP) - on hemodynamic, morphofunctional and cognitive parameters of robust older women. Methods: Forty-two older women were randomized allocated into one of the three experimental groups: NP, DUP, and control group (CG). Evaluations of the hemodynamic, morphofunctional and cognitive parameters occurred before, during and after six months. The exercise groups performed the program of exercise twice a week over 22 weeks. In NP, the two weekly sessions were based on 3 sets of 8-10 repetitions at a difficult intensity. However, in DUP, a power exercise session based on 3 sets of 8-10 repetitions at a moderate intensity was added in the first session of the week.


Eligibility criteria: Inclusion Criteria:

* Aged ≥60 years;
* Female;
* Not having been part of a systematic program of physical exercises in the last 6 months;
* MEEM score \>19 points;
* Kihon checklist score \>10 points;
* Capacity to perform the basic and instrumental activities of daily living according to Katz and Pfeffer indexes;
* Self-reported good memory;
* Complete all measurements.

Exclusion Criteria:

* Changes on antihypertensive medication in the past 6 months prior to inclusion in the study;
* Cardiovascular disease (i.e., acute myocardial infarction, stroke, peripheral arterial disease, and transient ischemic disease)
* Metabolic disease (i.e., diabetes mellitus type I or II), pulmonary disease (i.e., emphysema)
* Neurological and/or psychiatric disease (i.e., Parkinson's or Alzheimer's disease)
* Skeletal muscle disorders
* Comorbidities associated with greater risk of falls
* Recent history of smoking or alcohol abuse
* Hormone replacement therapy and/or psychotropic drugs.

Primary outcomes:
measure: Changes in transfer capacity in seconds
timeFrame: 6 months
Secondary outcomes:
measure: Changes in fat-free mass in kg
timeFrame: 6 months
measure: Changes in overall cognitive capacity in points
timeFrame: 6 months
measure: Changes in blood pressure in mmHg
timeFrame: 6 months
measure: Changes in shor-term memory in points
timeFrame: 6 months
Other outcomes:
Locations:
Study officials:
References:
citation: Coelho-Junior HJ, Goncalves IO, Camara NOS, Cenedeze MA, Bacurau RF, Asano RY, Santana J, Caperuto E, Uchida MC, Rodrigues B. Non-periodized and Daily Undulating Periodized Resistance Training on Blood Pressure of Older Women. Front Physiol. 2018 Nov 27;9:1525. doi: 10.3389/fphys.2018.01525. eCollection 2018.