Clinical trial NCT04691609: Assiut University Registry for ACS Patients During COVID-19 Pandemic
Official title: Assiut University Registry for ACS Patients During COVID-19 Pandemic
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: ACS-COVID-19-Assiut
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2020-12-31
Enrollment: 2500
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: ACS patients admitted to Assiut university heart hospital either male or female, young or old, COVID-19 confirmed, suspected or even excluded.

Brief summary: To register pathological events occurring to all acute coronary syndrome patients coming to Assiut university heart hospital through one year during COVID- 19 pandemic

Detailed description: In the face of the quickly evolving coronavirus disease 2019 (COVID-19) pandemic, many health-care systems around the globe have modified their routine management of patients presenting with acute cardiovascular emergencies including patients with ACS.A unifying theme in the new management strategies is the adoption of new restrictive measures to meet the challenges of increased risk of infection of health-care workers; limited numbers of beds, shortage of personal protective equipment (PPE), inadequate number of protected catheterization rooms; and the clinical overlap between ACS and COVID-19 infection in some of patients.

In developing countries, with an already strained health system due to economic problems, the situation is more challenging and needs the formulation of efficient protocols that can accommodate several medical and socioeconomic challenges.

Egypt, with an estimated population of 100 million, is facing exceptional challenges during the COVID-19 crisis. Because large scale use of polymerase chain reaction (PCR) test for SARS-CoV-2 in a large population is a problem, the prevalence of COVID-19 infection in Egypt is unknown. Furthermore, the supply of PPE falls far short of demands with lack of professionally protected cardiac catheterization rooms. With progression of the pandemic in such a large population, care of COVID-19 patients is expected to rapidly overwhelm the supplies, beds, and staff available in Egyptian hospitals.

The Cardiology Department in Assiut university hospital has revised the management protocols for ACS patients and implemented new management protocols both for patients with ST-segment elevation myocardial infarction (STEMI) and Non-ST-segment elevation acute coronary syndromes (NSTE-ACS).

Eligibility criteria: Inclusion Criteria:

* Patients presenting with symptoms or ECG indicative of acute coronary syndrome admitted to Assiut heart hospital

Exclusion Criteria:

* The only exclusion criteria is refusal of the patient to participate in the study

Primary outcomes:
measure: Main Number, distribution and oucome of all ACS patients coming to Assiut heart hospital
timeFrame: about 1 year
Secondary outcomes:
measure: To register pathological events occurring to all acute coronary syndrome patients coming to Assiut university heart hospital through one year during COVID- 19 pandemic
timeFrame: about 1 year
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Samah ObiedAllah Fouad
state: Resident
Study officials:
affiliation: aymankhairy11@gmail.com
name: Ayman Khairy Hassan, Lecturer
role: STUDY_DIRECTOR
References: