Clinical trial NCT04987619: Effect of Beetroot Juice Supplements on Lower-limb Strength in Females
Official title: Acute Effects of Beetroot Juice Supplements on Lower-limb Strength and Muscular Endurance in Physically Active Women: Double-blind Crossover Randomized Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Muscular Endurance
Keywords: Explosive force production
Beetroot juice
Beetroot
muscular endurance
Lead sponsor: Maimónides Biomedical Research Institute of Córdoba
Sponsor class: OTHER
First posted: 2021-08-03
Enrollment: 11
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: The experimental procedure will consist of three visits, separate from each other by one week, to achieve the total elimination of any effects caused by BJR as well as the optimal recovery of the participants.
Primary purpose: OTHER

Brief summary: This study aims to evaluate the effects of beetroot juice supplements on lower-limb strength and muscular endurance in physically active women, due to the presence of NO3- in beetroot juice.

Detailed description: Beetroot juice (BJR) is used as an ergogenic aid, but no study has analyzed its' effects on explosive force production in physically active women. It has been proposed that females could blunt reduction of NO2- to NO based on a higher oxidative skeletal muscle phenotype than males. However, it has been observed a higher increase on plasma NO2- levels after supplementation compared to and a greater enhancement on muscle contractile function.

Based on the absence of any study that has analyzed the effect of NO3- supplements on jump ability and power production on weightlifting on female population; the purpose of this study will be to investigate the possible ergogenic effect of BJR on physically active women on explosive force production and muscular endurance in a lower-limb body weightlifting protocol, due to the presence of NO3- in BJR and its effects.

Eligibility criteria: Inclusion Criteria:

* Physically active females with 18-30 years of age
* More than 6 months on RT training programs
* Be familiarized with back squat, leg press and leg extension exercises
* Not consuming any type of nutritional supplement or anabolic substances in the previous three months or during the study
* Not suffering from a musculoskeletal injury that could interfere with the exercise protocol during the investigation

Exclusion Criteria:

* None

Primary outcomes:
measure: Change of height reached in jump
timeFrame: Week 1, 2 and 3.
Secondary outcomes:
measure: Movement velocity
timeFrame: Visit 1 (week 1), 2 (week 2) and 3 (week 3).
measure: Power on back squat
timeFrame: Visit 1 (week 1), 2 (week 2) and 3 (week 3).
measure: Muscular endurance test
timeFrame: Visit 1 (week 1), 2 (week 2) and 3 (week 3).
measure: Rating of perceived exertion (RPE).
timeFrame: Visit 1 (week 1), 2 (week 2) and 3 (week 3).
Other outcomes:
Locations:
city: Lavras
country: Brazil
facility: Studies Research Group in Neuromuscular Responses (GEPREN), University of Lavras
city: Córdoba
country: Spain
facility: Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba
city: Córdoba
country: Spain
facility: Metabolism and Investigation Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC),Reina Sofia University Hospital, University of Cordoba
city: Córdoba
country: Spain
facility: Department of Food Science and Technology, Rabanales University Campus, University of Cordoba
city: Córdoba
country: Spain
facility: Department of Nursing Pharmacology and Physiotherapy, Faculty of Medicine and Nursing, University of Córdoba
city: Sevilla
country: Spain
facility: Departamento de Motricidad Humana y Rendimiento Deportivo, Universidad de Sevilla
Study officials:
affiliation: Hospital Universitario Reina Sofía
name: Jose Manuel Jurado Castro
role: PRINCIPAL_INVESTIGATOR
References: