Clinical trial NCT04383600: Flapless Mops for Acceleration of Canine Retraction
Official title: Efficacy of Micro-osteoperforations on the Rate of Maxillary Canine Retraction: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dental Malocclusions
Angle Class II, Division 1
Bimaxillary Protrusion
Keywords: MOPs
micro-osteoperforation
acceleration
orthodontic tooth movement
Lead sponsor: Al-Azhar University
Sponsor class: OTHER
First posted: 2020-05-12
Enrollment: 12
Sex: ALL
Minimum age (years): 14
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the present clinical study was directed to evaluate the effectiveness of micro-osteoperforations on the rate of canine retraction; in addition, the potential risk for root resorption during maxillary canine retraction.

Detailed description: The aim of the present clinical study was directed to evaluate the effectiveness of micro-osteoperforations on the rate of canine retraction; in addition, the potential risk for root resorption during maxillary canine retraction.

This study was conducted on a total sample of 24 canines of 12 patients, 8 females and 4 males, with mean age was 16.17 ± 2.29 years old who required therapeutic extraction of maxillary 1st premolars and canine retraction. They were selected randomly from the Outpatient Clinic, Department of Orthodontics, Faculty of Dental Medicine (Boys), Al-Azhar University, Cairo, Egypt.

Both maxillary canines, in each patient, were randomly assigned to either an experimental side or the control side in a simple split-mouth design. In the experimental side, micro-osteoperforations was performed distal to the maxillary canine before starting retraction, while the canines in the contralateral control side were retracted without micro-osteoperforations.

Extraction was done at the start of the treatment, and before fitting of the orthodontic appliance. Then upper dental arches were leveled and aligned using conventional sequences of wires.

Three flapless micro-osteoperforations was performed by using orthodontic miniscrews distal to the maxillary canines in the experimental side before starting retraction. Each perforation was 1.6 mm in diameter and 3-4 mm depth into the bone. Canines were completely retracted on 0.016 × 0.022 ̋ stainless steel wires by using closed coil spring delivered 150 gm force.

Patients were followed up every 28 days until complete canine retraction. Routine orthodontic records were obtained for each patient before treatment.

Additionally, a full skull CBCT images were taken before treatment and immediately after canine retraction.

The rate of canine retraction was assessed clinically; in addition, cone beam CT (CBCT) scans were used to assess the amount of canine retraction root length changes. Also anchorage loss of first permanent molars were assessed.

The treatment results were compared clinically and radiographically (CBCT).

Eligibility criteria: Inclusion Criteria:

1. An age ranged between 14 to 18 years.
2. Class II division 1 malocclusion or Class I bimaxillary protrusion with mild or no crowding. Wherever crowding was present, it was symmetrical on both sides of the arch.
3. Patients who diagnosed to require extraction of at least maxillary first premolars bilaterally as a part of their treatment plan.
4. Complete permanent dentition (3rdmolars were not included).
5. Good oral and general health.
6. No history of periodontal problems.
7. No therapeutic intervention planned involving intermaxillary or other intraoral or extraoral appliances during the study period.

Exclusion Criteria:

1. Blocked out or impacted maxillary canines.
2. Transverse and/or vertical skeletal dysplasia or craniofacial anomalies.
3. Systemic diseases or regular use of medications that could interfere with orthodontic treatment.
4. Previous orthodontic treatment.

Primary outcomes:
measure: Rate of canine retraction
timeFrame: change from start of canine retraction until complete space closure up to 6 months
measure: Canine root length changes
timeFrame: change from start of orthodontic treatment until complete space closure up to 9 months
Secondary outcomes:
measure: Anchorage loss of maxillary first permanent molars.
timeFrame: change from start of orthodontic treatment until complete space closure up to 9 months
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Al azhar university
Study officials:
affiliation: Al-Azhar University
name: Ahmed El Awady
role: PRINCIPAL_INVESTIGATOR
References: