Clinical trial NCT05015517: ESP Block vs FIB in Patients Undergoing Hip Arthroplasty
Official title: Comparison of Ultrasound Guided Erector Spinae Block and Supra-inguinal Fascia Iliaca Block for Postoperative Analgesia in Patients Undergoing Hip Arthroplasty: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Hip Arthropathy
Keywords: Erector spinae block
Fascia iliaca block
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2021-08-20
Enrollment: 54
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The aim of this study is to compare between the analgesic efficacy of ESP block and FIB in patients undergoing hip arthroplasty.

Detailed description: Hip arthroplasty surgery is usually associated with severe postoperative pain. Several modalities are usually used for postoperative analgesia in these patients, those include; intravenous analgesia, neuraxial analgesia and peripheral nerve blocks.

Peripheral nerve blocks have several advantages such as; potent analgesia, lower motor impairment and minimal systemic complications.

Lumbar plexus block and supra-inguinal fascia iliaca block (FIB) are the most commonly performed peripheral nerve blocks for hip surgeries.

Fascia iliaca block is one of the most common techniques for pain control after hip surgeries; it can be regarded as an anterior approach of the lumbar plexus. It provides analgesia through spread of local anaesthetic to the femoral and lateral cutaneous femoral nerves.

Ultrasound guided erector spinae plane (ESP) block is a recent regional anesthetic technique. It was first described in 2016 for acute and chronic thoracic pain management. It is a paraspinal fascial plane block that provides analgesia through injecting local anesthetic drugs to block the ventral and dorsal rami of spinal nerves in the paravertebral area.

To the best of the investigators knowledge, the use of ESP block in hip surgery was only investigated in one study and few case reports. Therefore, further randomized controlled studies are needed to prove this hypothesis.

This study aims to investigate the efficacy of ESP block in hip replacement compared to the supra-inguinal FIB.

The investigators hypothesize that erector spinae block may provide better postoperative analgesia than fascia iliaca block, since erector spinae block provides analgesic cover for the entire lumbar plexus rather than just peripheral nerves provided by fasicia iliaca.

Eligibility criteria: Inclusion Criteria:

* Age between 18 and 65 years
* ASA grade I to II
* Patients scheduled for hip replacement surgeries under subarachnoid block (SAB) e.g. hip hemi-arthroplasty, total hip arthroplasty

Exclusion Criteria:

* Patient refusal
* Age below 18 or above 65 years.
* ASA grade III to IV
* Patients with known allergies to any of the drugs used.
* Contraindication to SAB eg. Coagulopathy, infection at the injection site, severe cardiopulmonary disease, diabetic or other neuropathies.
* Patients receiving opioids for chronic analgesic therapy
* Inability to comprehend visual analogue scale (VAS)
* Infection at site of erector spinae or fascia iliaca block.
* Body mass index \>35 kg/m2

Primary outcomes:
measure: Total morphine requirements
timeFrame: 24 hours postoperatively
Secondary outcomes:
measure: Visual analogue pain score
timeFrame: at rest at 2, 4, 6, 12, 18, and 24 hours postoperatively
measure: Time to first postoperative analgesic request
timeFrame: 24 hours postoperatively
measure: Quadriceps muscle power strength
timeFrame: at 6, 12 and 24 hours postoperatively
Other outcomes:
Locations:
Study officials:
affiliation: Cairo University
name: Ashraf RA Aswa, Professor
role: STUDY_DIRECTOR
References: