Clinical trial NCT02075424: Descriptive Study of Biological Stress and Perceived Stress at the Center 15
Official title: Descriptive Study of Biological Stress and Perceived Stress in Call Regulation Operators and Doctors When Processing a Call at the Center 15
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Physiological Stress
Psychological Stress
Keywords: stress
cortisol
emergency call center
hospital staff
Lead sponsor: Centre Hospitalier Régional Metz-Thionville
Sponsor class: OTHER
First posted: 2014-03-03
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: The purpose of this study is to describe biological stress (cortisolemia) and perceived stress in Emergency Call Center Operators and Doctors while processing a center 15 call.

Detailed description: Sample description : qualitative variables be expressed as percentages, numbers and 95% confidence intervals Quantitative variables will be expressed as means, standard deviations or medians, range, interquartile intervals Description of biological stress : it will be described by calculating the difference between the observed peek or peeks of cortisol ans the cortisol level measured at rest (means, standard deviations or medians, range, interquartile intervals) Description of perceived stress : the AVS will be described in terms of means and standard deviation Comparison of the peek-delta/base level of cortisol in the 3 different workstations of the call center operators according to the non parametrical Kruskall Wallis test. Same for the lengthof service of the call operator, the severity of the call and the status of the doctor The AVS score (perceived stress) will be compared to the peek-delta/base level of cortisol (biological stress) thanks to the Spearmann correlation coefficient.

Eligibility criteria: Inclusion Criteria:

* medical and paramedical staff from the center 15 (call operators, emergency doctors and general practitioners)
* healthy volunteers having received the specific information letter regarding the sudy and having signed the clarified consent form
* healthy volunteers are affiliated to the french social welfare

Exclusion Criteria:

* chronic alcoholism
* women under oestroprogestative hormonal treatment
* high level athletes
* healthy volunteers under steroids treatment
* healthy volunteers suffering from a mental health related disorder
* fever on the day the sample is taken
* healthy volunteers with endocrine disorders

Primary outcomes:
measure: biological stress by salivary cortisol secretion
timeFrame: every 15 minutes after the emergency call and during 2 hours
Secondary outcomes:
measure: perceived stress : VAS and SPPN questionnaire
timeFrame: VAS is assessed four times (once after each emergency call) during the first salivary sampling. SPPN once, on day 1, remote the emergency call (within the hourspreceding or following the emergency call)
Other outcomes:
Locations:
city: Metz cedex 03
country: France
facility: Centre Hospitalier Régional Metz Thionville
Study officials:
affiliation: Centre Hospitalier Régional Metz-Thionville
name: Michel Aussedat, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Weibel L, Gabrion I, Aussedat M, Kreutz G. Work-related stress in an emergency medical dispatch center. Ann Emerg Med. 2003 Apr;41(4):500-6. doi: 10.1067/mem.2003.109.
citation: Nakajima Y, Takahashi T, Shetty V, Yamaguchi M. Patterns of salivary cortisol levels can manifest work stress in emergency care providers. J Physiol Sci. 2012 May;62(3):191-7. doi: 10.1007/s12576-012-0197-8. Epub 2012 Feb 19.
citation: Kirschbaum C, Hellhammer DH. Salivary cortisol in psychobiological research: an overview. Neuropsychobiology. 1989;22(3):150-69. doi: 10.1159/000118611.
citation: Hellhammer DH, Wust S, Kudielka BM. Salivary cortisol as a biomarker in stress research. Psychoneuroendocrinology. 2009 Feb;34(2):163-171. doi: 10.1016/j.psyneuen.2008.10.026. Epub 2008 Dec 18.
citation: Kirschbaum C, Hellhammer DH. Salivary cortisol in psychoneuroendocrine research: recent developments and applications. Psychoneuroendocrinology. 1994;19(4):313-33. doi: 10.1016/0306-4530(94)90013-2.