Clinical trial NCT00989924: Research on the Correlation Among Magnetocardiography Patterns and Known Cardiovascular Risk Factors in Diabetic Patients
Official title: Research on the Correlation Among Magnetocardiography Patterns and Known Cardiovascular Risk Factors in Diabetic Patients
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Diabetes Mellitus
Keywords: Diabetes mellitus
Coronary heart disease
Magnetocardiography
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
First posted: 2009-10-06
Enrollment: 1100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The Diabetic patient who receives follow-up at NTUH diabetics caring network

Brief summary: The purpose of this study is to evaluate the correlation among magnetocardiography (MCG) patterns and various known cardiovascular risk factors.

Detailed description: It is well understood that diabetes mellitus (DM) causes various micro- and macrovascular complications. Among them, coronary heart diseases (CHDs) claim most mortality, and diabetes has been considered as "CHD equivalent". Furthermore, the risk of CHD has been noticed to increase in the pre-diabetic stage, suggesting the development of CHD may start in a rather early stage of the disease. Thus, early detection of CHD in diabetic patients seems to be important. However, currently exam methods for CHD in diabetic patients seemed to have their limitations.

Developed in the 1960s, magnetocardiography (MCG) is designed to detect the weak magnetic field generated by the electrical activity of the heart, and has been used widely in the study of fetal cardiac electrophysiology, arrhythmia and ischemic heart disease. However, the MCG pattern in diabetic patients is not fully understood. The aim of the study is to clarify the correlation among various cardiovascular risk factors and MCG pattern in diabetic patients. And, according to the results of the study, we'll evaluate the potentiality of MCG in early diagnosis of CHD in diabetic patients.

Eligibility criteria: Inclusion Criteria:

* Clear consciousness
* Met the diagnostic criteria of DM published by the American Diabetes Association in 2009

Exclusion Criteria:

* not suitable for MCG exam (ex. with pacemaker implantation or indwelling metallic device)

Primary outcomes:
measure: The smooth index of corrected QT interval (SIQTC) measured by MCG
timeFrame: as the MCG exam is over
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital
Study officials:
affiliation: National Taiwan University Hospital
name: Lee-Ming Chuang, MD. Ph.D.
role: STUDY_DIRECTOR
affiliation: National Taiwan University Hospital
name: Chau-Chung Wu, MD. Ph.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: National Taiwan University Hospital
name: Yi-Der Jiang, MD.
role: PRINCIPAL_INVESTIGATOR
affiliation: National Taiwan University Hospital
name: Tien-Jyun Chang, MD. Ph.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: National Taiwan University Hospital, Yun-Lin Branch
name: Chih-Hung Lin, MD.
role: PRINCIPAL_INVESTIGATOR
References: