Clinical trial NCT03808363: Effectiveness of High Intensity Interval Training (HIIT) on Improving Cardiometabolic Health After SCI
Official title: High-intensity Interval Training Versus Moderate Intensity Continuous Training as a Means to Improve Cardiometabolic Health After Spinal Cord Injury
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Metabolic Syndrome
Cardiovascular Diseases
Keywords: Metabolic Syndrome
Spinal Cord Injury
Cardiovascular Disease
High Intensity Interval Training
Lead sponsor: Brock University
Sponsor class: OTHER
First posted: 2019-01-17
Enrollment: 8
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: 6 week exercise intervention testing the efficacy of high intensity interval training as compared to current research supporting moderate intensity continuous exercise as a means to mitigate cardiometabolic decline following spinal cord injury
Primary purpose: PREVENTION

Brief summary: Testing the efficacy of high intensity interval training (HIIT), as compared to current research supporting moderate intensity continuous training (MICT), as a means to improve cardiometabolic health after spinal cord injury.

Detailed description: This study aims to challenge the effectiveness of the current aerobic exercise recommendations for individuals with spinal cord injuries (SCI). Currently, moderate intensity continuous training (MICT) is suggested however this study intends to explore the effectiveness of high intensity interval training (HIIT). To do so, approximately 8 individuals with SCI will be undergo a 6 week HIIT intervention consisting of 3 sessions per week. With a focus on cardiometabolic health markers (listed in outcome measure section), we aim to provide support for HIIT as a viable method of mitigating cardiovascular risk in a SCI population.

Eligibility criteria: Inclusion Criteria:

* Individuals with a spinal cord injury (paraplegia or tetraplegia, complete or incomplete) who are at least one-year post injury.
* Declared medically stable, and able to communicate clearly in English.

Primary outcomes:
measure: Waist circumference (inches)
timeFrame: 6 weeks
measure: Cholesterol
timeFrame: 6 weeks
measure: Triglycerides
timeFrame: 6 weeks
measure: Glycated Hemoglobin (HbA1c)
timeFrame: 6 weeks
measure: Tumor necrosis factor (TNF-a)
timeFrame: 6 weeks
measure: Interleukin - 10 (IL-10)
timeFrame: 6 weeks
measure: Pulse Wave Velocity
timeFrame: 6 weeks
measure: Blood pressure
timeFrame: 6 weeks
measure: Peak Oxygen Consumption (VO2 peak)
timeFrame: 6 weeks
measure: C Reactive Protein (CRP)
timeFrame: 6 weeks
measure: Leptin
timeFrame: 6 weeks
measure: Adiponectin
timeFrame: 6 weeks
Secondary outcomes:
measure: Physical Activity Enjoyment Scale (PACES)
timeFrame: 6 weeks
Other outcomes:
Locations:
city: St. Catherines
country: Canada
facility: Brock University
state: Ontario
Study officials:
affiliation: Masters Student
name: Mitchel Gibson, BKin
role: PRINCIPAL_INVESTIGATOR
affiliation: Masters Student
name: Aaron Donst, BKin
role: PRINCIPAL_INVESTIGATOR
References: