Clinical trial NCT00408265: Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study
Official title: Smoking Cessation in Substance Abuse Treatment Patients: A Feasibility Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Nicotine Dependence
Keywords: Nicotine Dependence
Contingency Management
Lead sponsor: UConn Health
Sponsor class: OTHER
Collaborators: name: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
First posted: 2006-12-06
Enrollment: 80
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to compare the effects of self-help materials for smoking cessation and self-help materials for smoking cessation plus prize-based contingency management (CM), in which prize incentives are available for breath and saliva samples that indicate smoking abstinence, in substance abuse treatment patients who want to quit smoking.

Detailed description: The specific aims of this study are: (1) to examine the efficacy of self-help materials compared to self-help materials plus prize contingency management (CM) for smoking abstinence in substance abuse treatment patients and (2) examine the effects of smoking abstinence on substance use and substance treatment retention. To address these specific aims, cigarette smokers entering treatment for alcohol, cocaine or heroin abuse or dependence, who report daily smoking (at least one cigarette per day) for the past year, and who meet other inclusion and exclusion criteria, are randomly assigned to receive self-help materials or self-help materials plus CM. Individuals in the CM group have the opportunity to win prizes, worth on average $1, $20, or $100, when they meet smoking abstinence criteria (CO \< 8ppm and salivary cotinine \< 10ng/mL). Participants meet with research staff 4 times/week during Weeks 1-4, 2 times/week during Weeks 5-8 and 1 time/week during Weeks 9-12. Follow-up interviews are scheduled 1, 3 and 6 months following the smoking quit date.

Eligibility criteria: Inclusion Criteria:

* meets diagnostic criteria for alcohol, cocaine or heroin abuse or dependence
* self-report daily smoking for at least the past year
* CO \> 8ppm
* interested in quitting smoking while in treatment,
* minimum age 18 years old
* willing to provide names, addresses and phone numbers of individuals to assist in locating the patient for follow-up evaluations
* English speaking

Exclusion Criteria:

* current use of NRT
* current use of bupropion
* serious, uncontrolled psychiatric illness (e.g., acute schizophrenia, suicide risk)
* dementia (Mini-mental status score of \<23)
* currently participating in another CM study at the clinic
* in recovery for pathological gambling

Primary outcomes:
measure: Percent negative CO readings
measure: Percent negative cotinine readings
measure: Longest period of continuous abstinence
Secondary outcomes:
measure: Self-reported frequency and severity of smoking
measure: Objective substance use
measure: Self-reported substance use
measure: Treatment retention
Other outcomes:
Locations:
city: Farmington
country: United States
facility: University of Connecticut Health Center
state: Connecticut
Study officials:
affiliation: UConn Health
name: Sheila M Alessi, PhD
role: PRINCIPAL_INVESTIGATOR
References: