Clinical trial NCT03607019: Social Deprivation Features in Intensive Care Unit Patients
Official title: Epidemiology and Prognostic Impact of Social Deprivation Features in Intensive Care Unit Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Socioeconomic Factors
Keywords: Intensive care
Critical care
Poverty
inequalities
Lead sponsor: Centre Hospitalier de Saint-Denis
Sponsor class: OTHER
First posted: 2018-07-31
Enrollment: 234
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All consecutive patients admitted to one of the participating ICUs during the study period

Brief summary: Socioeconomic inequalities are increasingly recognised as an important public health issue, and it is now well established that patients with socioeconomic deprivation (SED) features demonstrate higher mortality and morbidity. The epidemiology and impact of SED on the specific population of ICU patients has been insufficiently investigated.

In this prospective multicenter study of patients admitted to 9 ICUs of the Paris area, the investigators aim to explore the epidemiology of SED features, and its impact on mortality and length of stay.


Eligibility criteria: Inclusion Criteria:

* Age ≥ 18 years
* Admission to one of the participating intensive care units

Exclusion Criteria:

* None

Primary outcomes:
measure: 30-day mortality
timeFrame: 30 days
Secondary outcomes:
measure: ICU length of stay
timeFrame: up to 12 weeks
measure: Hospital length of stay
timeFrame: up to 12 weeks
measure: ICU mortality
timeFrame: up to 12 weeks
Other outcomes:
measure: 30-day mortality of pre-specified subgroup of undocumented immigrants
timeFrame: 30 days
measure: 30-day mortality of pre-specified subgroup of deprived patients aged between 18 and 25 years old
timeFrame: 30 days
Locations:
city: Boulogne-Billancourt
country: France
facility: Centre Hospitalier Universitaire Ambroise Paré
city: Colombes
country: France
facility: Centre Hospitalier Universitaire Louis Mourier
city: Corbeil-Essonnes
country: France
facility: Centre Hospitalier Sud-Francilien
city: Créteil
country: France
facility: Centre Hospitalier Universitaire Henri Mondor
city: Jossigny
country: France
facility: Grand Hopital de l'Est Francilien
city: Longjumeau
country: France
facility: Groupe Hospitalier Nord-Essone
city: Montreuil
country: France
facility: Centre Hospitalier Intercommunal André Grégoire
city: Paris
country: France
facility: Centre Hospitalier Universitaire Lariboisière
city: Saint-Denis
country: France
facility: Centre Hospitalier de Saint-Denis
Study officials:
affiliation: Centre Hospitalier de Saint-Denis
name: Etienne de Montmollin, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Centre Hospitalier de Saint-Denis
name: Morgan Benais, MD
role: STUDY_CHAIR
affiliation: Centre Hospitalier de Saint-Denis
name: Daniel Da Silva, MD
role: STUDY_CHAIR
References:
citation: Marmot M, Allen J, Bell R, Bloomer E, Goldblatt P; Consortium for the European Review of Social Determinants of Health and the Health Divide. WHO European review of social determinants of health and the health divide. Lancet. 2012 Sep 15;380(9846):1011-29. doi: 10.1016/S0140-6736(12)61228-8. Epub 2012 Sep 8.
citation: Welch CA, Harrison DA, Hutchings A, Rowan K. The association between deprivation and hospital mortality for admissions to critical care units in England. J Crit Care. 2010 Sep;25(3):382-90. doi: 10.1016/j.jcrc.2009.11.003. Epub 2010 Jan 15.
citation: Zager S, Mendu ML, Chang D, Bazick HS, Braun AB, Gibbons FK, Christopher KB. Neighborhood poverty rate and mortality in patients receiving critical care in the academic medical center setting. Chest. 2011 Jun;139(6):1368-1379. doi: 10.1378/chest.10-2594. Epub 2011 Mar 31.
citation: Latour J, Lopez V, Rodriguez M, Nolasco A, Alvarez-Dardet C. Inequalities in health in intensive care patients. J Clin Epidemiol. 1991;44(9):889-94. doi: 10.1016/0895-4356(91)90051-a.
citation: Bein T, Hackner K, Zou T, Schultes S, Bosch T, Schlitt HJ, Graf BM, Olden M, Leitzmann M. Socioeconomic status, severity of disease and level of family members' care in adult surgical intensive care patients: the prospective ECSSTASI study. Intensive Care Med. 2012 Apr;38(4):612-9. doi: 10.1007/s00134-012-2463-x. Epub 2012 Jan 25.
citation: Bige N, Hejblum G, Baudel JL, Carron A, Chevalier S, Pichereau C, Maury E, Guidet B. Homeless Patients in the ICU: An Observational Propensity-Matched Cohort Study. Crit Care Med. 2015 Jun;43(6):1246-54. doi: 10.1097/CCM.0000000000000944.