Clinical trial NCT03406065: Sodium Bicarbonate Supplementation in Combat Sports Athletes
Official title: The Effect of Sodium Bicarbonate Supplementation on Physical and Specific Performance Capacity in Combat Sports Athletes
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
PHASE3
Conditions: Supplementation
Sport
Keywords: Sodium bicarbonate
NaHCO3
Combat Sports
Physical capacity
Dummy test
Lead sponsor: Poznan University of Life Sciences
Sponsor class: OTHER
Collaborators: name: Poznan University of PhysED
First posted: 2018-01-23
Enrollment: 64
Sex: ALL
Minimum age (years): 17
Maximum age (years): 30
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on physical and specific performance capacity, as well as concentrations of the selected biochemical blood markers in trained combat sports athletes, in a randomised, double-blind, placebo-controlled trial.

Detailed description: Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive-dose NaHCO3 ingestion on physical capacity and specific performance capacity, and concentrations of the selected biochemical blood markers in trained combat sports athletes, in a randomised, double-blind, placebo-controlled trial.

Eligibility criteria: Inclusion Criteria:

* written informed consent from all participants before the study (included aslo informed consents to the participation in the study of athletes under the age of 18 obtained from their parents)
* a current medical clearance to practice sports,
* training experience: at least 4 years (of combat sport training),
* minimum of 4 workout sessions (combat sport) a week,

Exclusion Criteria:

* current injury,
* any health-related contraindication,
* declared general feeling of being unwell,
* unwilling to follow the study protocol.

Primary outcomes:
measure: Changes in anaerobic capacity after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in specific performance capacity after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
Secondary outcomes:
measure: Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in blood hematocrit levels after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in polyphenols and albumin concentration
timeFrame: Baseline and after 10 days
measure: Changes in FRAP concentration
timeFrame: Baseline and after 10 days
Other outcomes:
Locations:
city: Poznań
country: Poland
facility: Poznan University of Life Sciences, ul.Wojska Polskiego 31
state: Wielkopolska
Study officials:
affiliation: Poznan University of Life Sciences, ul. Wojska Polskiego 31, Poznań, Wielkopolska, Poland, 60-624
name: Jan Jeszka, Professor
role: STUDY_CHAIR
References: