Clinical trial NCT01972841: This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive Bladder
Official title: A Randomized, Double-Blind, Parallel-Group, Placebo- and Active-Controlled, Multi-center Study to Evaluate the Efficacy, Safety and Tolerability of Combinations of Solifenacin Succinate and Mirabegron Compared to Solifenacin Succinate and Mirabegron Monotherapy in the Treatment of Overactive Bladder
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Urinary Bladder Overactive
Urinary Bladder Diseases\Urologic Diseases
Overactive Bladder
Urgency Incontinence
Keywords: Combination Therapy
Mirabegron
Overactive Bladder
Urgency
Urinary Incontinence
Nocturia
Solifenacin Succinate
Lead sponsor: Astellas Pharma Inc
Sponsor class: INDUSTRY
First posted: 2013-10-31
Enrollment: 3527
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study was to examine how well two medicines (solifenacin succinate and mirabegron) combined work compared to each medicine alone in the treatment of bladder problems.


Eligibility criteria: Inclusion Criteria:

* Subject was willing and able to complete the micturition diary and questionnaires correctly and able to measure his/her vital signs at home at stipulated time points, using the device provided by the study personnel, and to adequately record the readings;
* Subject had symptoms of "wet" OAB (urinary frequency and urgency with incontinence) for at least 3 months;

Exclusion Criteria:

* Subject had significant PVR volume (\> 150 mL);
* Subject had a neurological cause for detrusor overactivity (e.g. neurogenic bladder, diabetic neuropathy with autonomic component or bladder involvement, or systemic or central neurological disease such as multiple sclerosis and Parkinson's disease with autonomic component or bladder involvement). An autonomic component could be inferred when autonomic functions were affected, including heart rate, blood pressure, perspiration and digestion.
* Subject had an indwelling catheter or practices intermittent self catheterization.
* Subject had chronic inflammation such as bladder pain syndrome /interstitial cystitis, symptomatic bladder stones or any previous or current radiation cystitis.
* Subject had received intravesical treatment in the past 12 months with e.g., botulinum toxin, resiniferatoxin, capsaicin.
* Subject had moderate to severe hepatic impairment
* Subject had severe renal impairment
* Subject had a clinically significant abnormal ECG
* Subject had a concurrent malignancy or history of cancer (except noninvasive skin cancer) within the last 5 years prior to screening.
* Subject had an average QTcF interval \> 450 ms for males or \> 470 ms for females based on the triplicate ECGs completed at Screening or is at risk of QT prolongation (e.g., family history of long QT syndrome, hypokalaemia).
* Subject had severe hypertension, which is defined as a sitting average systolic blood pressure ≥ 180 mmHg and/or average diastolic blood pressure ≥ 110 mmHg.

Primary outcomes:
measure: Change From Baseline to End of Treatment (EoT) in Mean Number of Incontinence Episodes Per 24 Hours
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in Mean Number of Micturitions Per 24 Hours
timeFrame: Baseline and EoT (up to 12 weeks)
Secondary outcomes:
measure: Change From Baseline to EoT in Mean Volume Voided Per Micturition
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in Overactive Bladder Questionnaire (OAB-q) Symptom Bother Score
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in Treatment Satisfaction-Visual Analogue Scale (TS-VAS)
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Number of Incontinence Episodes at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Number of Incontinence Episodes
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8 and 12 in Mean Number of Incontinence Episodes Per 24 Hours
timeFrame: Baseline and weeks 4, 8 and 12
measure: Change From Baseline to Weeks 4, 8 and 12 in Mean Number of Micturitions Per 24 Hours
timeFrame: Baseline and weeks 4, 8 and 12
measure: Change From Baseline to Weeks 4, 8 and 12 in Mean Volume Voided Per Micturition
timeFrame: Baseline and weeks 4, 8 and 12
measure: Change From Baseline to EoT in Corrected Micturition Frequency
timeFrame: Baseline and Week 12
measure: Number of Urgency Incontinence Episodes at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Number of Urgency Incontinence Episodes
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Mean Number of Urgency Incontinence Episodes Per 24 Hours
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Mean Number of Urgency Episodes (Grade 3 or 4) Per 24 Hours
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Number of Nocturia Episodes at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Number of Nocturia Episodes
timeFrame: Baseline and weeks 4, 8, 12, and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Mean Number of Nocturia Episodes Per 24 Hours
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Number of Pads Used at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8 and 12 (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Number of Pads Used
timeFrame: Baseline and weeks 4, 8, 12 and EOT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Mean Number of Pads Used Per 24 Hours
timeFrame: Baseline and weeks 4, 8 and 12 (up to 12 weeks)
measure: Number of Incontinence-Free Days at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Number of Days With < 8 Micturitions at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8,12 and EoT (up to 12 weeks)
measure: Number of Incontinence-Free Days With < 8 Micturitions at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Patient Perception of Bladder Condition Questionnaire (PPBC)
timeFrame: Baseline and weeks 4, 8, 12, EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8 and 12 in the OAB-q Symptom Bother Score
timeFrame: Baseline and weeks 4, 8 and 12
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in OAB-q Health-Related Quality of Life Questionnaire (HRQL) Total Score
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in OAB-q HRQL Subscale Score: Coping
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in OAB-q HRQL Subscale Score: Concern
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in OAB-q HRQL Subscale Score: Sleep
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in OAB-q HRQL Subscale Score: Social
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Patient's Global Impression of Change (PGIC) Scale: Impression in Bladder Symptoms at Week 12 and EoT
timeFrame: Week 12 and EoT (up to 12 weeks)
measure: PGIC Scale: Impression in General Health at Week 12 and EoT
timeFrame: Week 12 and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in European Quality of Life in 5 Dimensions (EQ-5D) Questionnaire Subscale Score: Mobility
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in EQ-5D Questionnaire Subscale Score: Self-Care
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in EQ-5D Questionnaire Subscale Score: Usual Activities
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in EQ-5D Questionnaire Subscale Score: Pain/Discomfort
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to EoT in EQ-5D Questionnaire Subscale Score: Anxiety/Depression
timeFrame: Baseline and EoT (up to 12 weeks)
measure: Change From Baseline to Week 12 and EoT in Work Productivity and Activity Impairment: Specific Health Problem Questionnaire (WPAI:SHP) Score: Percent Work Time Missed
timeFrame: Baseline and week 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Week 12 and EoT in WPAI:SHP Score: Percent Impairment While Working
timeFrame: Baseline and week 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Week 12 and EoT in WPAI:SHP Score: Percent Overall Work Impairment
timeFrame: Baseline and week 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Week 12 and EoT in WPAI:SHP Score: Percent Activity Impairment
timeFrame: Baseline and week 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 8 and 12 in TS-VAS
timeFrame: Baseline and week 4, 8 and 12
measure: Percentage of Participants With Zero Incontinence Episodes Per 24 Hours Using the Last 3 Diary Days at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants With ≥ 10 Points Improvement From Baseline in the OAB-q Symptom Bother Score at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants With ≥ 10 Points Improvement From Baseline in HRQL Total Score at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants With 50% Reduction in Mean Number of Incontinence Episodes Per 24 Hours at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants for Micturition Frequency Normalization at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8 , 12 and EoT (up to 12 weeks)
measure: Percentage of Participants With Zero Incontinence Episodes Per 24 Hours Using the Last 7 Diary Days at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants With ≥ 1 Point Improvement From Baseline in PPBC at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants With Major (≥ 2 Points) Improvement From Baseline in PPBC at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants Who Were Double Responders (50% Reduction in Mean Number of Incontinence Episodes Per 24 Hours and at Least 10 Points Improvement on OAB-q Symptom Bother Scale) at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants Who Were Double Responders (50% Reduction in Mean Number of Incontinence Episodes Per 24 Hours and at Least 10 Points Improvement on OAB-q HRQL Total Score) at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants Who Were Double Responders (50% Reduction in Mean Number of Incontinence Episodes Per 24 Hours and at Least 1 Point Improvement on PPBC) at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants Who Were Triple Responders (50% Reduction in Mean Number of Incontinence Episodes Per 24 Hours, at Least 10 Points Improvement on OAB-q Symptom Bother Scale and at Least 1 Point Improvement on PPBC) at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Percentage of Participants Who Were Triple Responders (50% Reduction in Mean Number of Incontinence Episodes Per 24 Hours, at Least 10 Points Improvement on OAB-q HRQL Total Score and at Least 1 Point Improvement on PPBC) at Weeks 4, 8, 12 and EoT
timeFrame: Weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Number of Participants With Treatment-Emergent Adverse Events (TEAEs)
timeFrame: From first dose of double-blind study drug up to 30 days after last dose of double-blind study drug (up to 16 weeks)
measure: Change From Baseline to Weeks 4, 8, 12 and EoT in Postvoid Residual (PVR) Volume
timeFrame: Baseline and weeks 4, 8, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in Mean 24-hours, Mean Daytime and Mean Nighttime Systolic Blood Pressure (SBP)
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in Mean 24-h, Mean Daytime and Mean Nighttime Diastolic Blood Pressure (DBP)
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in Mean 24-h, Mean Daytime and Mean Nighttime Pulse Rate (PR)
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in Mean SBP in the Time to Maximum Concentration (Tmax) Window
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in Mean DBP in the Tmax Window
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in Mean PR in the Tmax Window
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Maximum 1-hour Change From Time-matched Baseline in SBP at Weeks 4, 12 and EoT
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Maximum 1-hour Change From Time-matched Baseline in DBP at Weeks 4, 12 and EoT
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Maximum 1-hour Change From Time-matched Baseline in PR at Weeks 4, 12 and EoT
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in SBP Peak/Trough Difference
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in DBP Peak/Trough Difference
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
measure: Change From Baseline to Weeks 4, 12 and EoT in PR Peak/Trough Difference
timeFrame: Baseline and weeks 4, 12 and EoT (up to 12 weeks)
Other outcomes:
Locations:
city: Mobile
country: United States
facility: Site US10049 Coastal Clinical Research, Inc.
state: Alabama
city: Mobile
country: United States
facility: Site US10112 TFI, LLC
state: Alabama
city: Chandler
country: United States
facility: Site US10104 Clinical Research Advantage, Inc.
state: Arizona
city: Phoenix
country: United States
facility: Site US10021 Beach Clinical Studies
state: Arizona
city: Anaheim
country: United States
facility: Site US10122 Orange County Research Institute
state: California
city: Cerritos
country: United States
facility: Site US10098 Skyline Research
state: California
city: Glendora
country: United States
facility: Site US10539 Citrus Valley Medical Research
state: California
city: Hawaiian Gardens
country: United States
facility: Site US10082 American Clinical Trials
state: California
city: Los Angeles
country: United States
facility: Site US10132 Axis Clinical Trials
state: California
city: Los Angeles
country: United States
facility: Site US10133 Axis Clinical Trials
state: California
city: Palo Alto
country: United States
facility: Site US10536 Stanford School of Medicine
state: California
city: Paramount
country: United States
facility: Site US10149 Bayview Research Group
state: California
city: Sacramento
country: United States
facility: Site US10559 UC Davis Medical Center
state: California
city: San Diego
country: United States
facility: Site US10003 San Diego Clinical Trials
state: California
city: San Diego
country: United States
facility: Site US10545 San Diego Institute for Sexual Medicine
state: California
city: Tarzana
country: United States
facility: Site US10106 West Coast Clinical Research
state: California
city: Valley Village
country: United States
facility: Site US10595 Bayview Research Group
state: California
city: Denver
country: United States
facility: Site US10034 Urology Center of Colorado
state: Colorado
city: Lakewood
country: United States
facility: Site US10070 Physicians' Research Options/Red Rocks OB/GYN
state: Colorado
city: Wheat Ridge
country: United States
facility: Site US10053 Western Clinical Research, Inc.
state: Colorado
city: Danbury
country: United States
facility: Site US10128 Clinical Research Center of CT
state: Connecticut
city: New Britain
country: United States
facility: Site US10018 Grove Hill Clinical Research
state: Connecticut
city: New Haven
country: United States
facility: Site US10170 Yale - New Haven Hospital West Haven VAMC
state: Connecticut
city: Waterbury
country: United States
facility: Site US10123 Chase Medical Research, LLC
state: Connecticut
city: Bradenton
country: United States
facility: Site US10060 Meridien Research
state: Florida
city: Hialeah
country: United States
facility: Site US10097 A.G.A. Clinical Trials DBA Neostart Group
state: Florida
city: Hialeah
country: United States
facility: Site US10148 Best Quality Research, Inc.
state: Florida
city: Hialeah
country: United States
facility: Site US10153 Palmetto Professional Research
state: Florida
city: Hialeah
country: United States
facility: Site US10159 Urological Research Network
state: Florida
city: Hialeah
country: United States
facility: Site US10534 South Florida Medical Research
state: Florida
city: Homestead
country: United States
facility: Site US10535 South Florida Medical Research
state: Florida
city: Jacksonville
country: United States
facility: Site US10165 East Coast Institute for Research
state: Florida
city: Jupiter
country: United States
facility: Site US10091 Health Awareness
state: Florida
city: New Port Richey
country: United States
facility: Site US10150 Suncoast Clinical Research, Inc.
state: Florida
city: Ocala
country: United States
facility: Site US10158 Renstar Medical Research
state: Florida
city: Orlando
country: United States
facility: Site US10124 Winter Park Urology Associates
state: Florida
city: Orlando
country: United States
facility: Site US10134 Compass Research, LLC
state: Florida
city: Pembroke Pines
country: United States
facility: Site US10009 South Broward Research
state: Florida
city: Pembroke Pines
country: United States
facility: Site US10540 Demaur Clinical Research, INC
state: Florida
city: Plantation
country: United States
facility: Site US10554 Private Practice
state: Florida
city: Sarasota
country: United States
facility: Site US10095 Florida Urology Specialists
state: Florida
city: Tallahassee
country: United States
facility: Site US10010 Southeastern Research Group, Inc
state: Florida
city: Wellington
country: United States
facility: Site US10014 Private Practice
state: Florida
city: Alpharetta
country: United States
facility: Site US10037 Atlanta Medical Research Institute
state: Georgia
city: Roswell
country: United States
facility: Site US10127 Perimeter North Medical Research, Inc.
state: Georgia
city: Sandy Springs
country: United States
facility: Site US10120 WR-Mount Vernon Clinical Research
state: Georgia
city: Shawnee Mission
country: United States
facility: Site US10024 GTC Research
state: Kansas
city: Wichita
country: United States
facility: Site US10078 Heartland Research Associates, LLC
state: Kansas
city: Lake Charles
country: United States
facility: Site US10088 Centex Studies, Inc.
state: Louisiana
city: Metairie
country: United States
facility: Site US10074 Medpharmics, LLC
state: Louisiana
city: Shreveport
country: United States
facility: Site US10025 Regional Urology, LLC
state: Louisiana
city: Glen Burnie
country: United States
facility: Site US10558 Chesapeake Urology Research Associates
state: Maryland
city: Owings Mills
country: United States
facility: Site US10560 Chesapeake Urology Research Associates
state: Maryland
city: Boston
country: United States
facility: Site US10282 Boston Clinical Trials
state: Massachusetts
city: Watertown
country: United States
facility: Site US10114 Bay State Clinical Trials, Inc.
state: Massachusetts
city: Grand Rapids
country: United States
facility: Site US10152 Female Pelvic Medicine & Urogynecology Institute
state: Michigan
city: Sartell
country: United States
facility: Site US10542 Adult & Pediatric Urology Group
state: Minnesota
city: Billings
country: United States
facility: Site US10110 Montana Health Research Institute, Inc.
state: Montana
city: Missoula
country: United States
facility: Site US10154 Montana Medical Research Inc
state: Montana
city: Lincoln
country: United States
facility: Site US10553 Women's Clinic of Lincoln
state: Nebraska
city: Las Vegas
country: United States
facility: Site US10140 IVCTLV
state: Nevada
city: Englewood
country: United States
facility: Site US10002 Urology Center Research Institute
state: New Jersey
city: Lawrenceville
country: United States
facility: Site US10051 AdvancedMed Research
state: New Jersey
city: Lawrenceville
country: United States
facility: Site US10047 Lawrence OBGYN Associates
state: New Jersey
city: Moorestown
country: United States
facility: Site US10162 Phoenix OB-GYN Associates, LLC
state: New Jersey
city: Albuquerque
country: United States
facility: Site US10011 Albuquerque Clinical Trials, Inc.
state: New Mexico
city: Albuquerque
country: United States
facility: Site US10015 Urology Group of New Mexico
state: New Mexico
city: Albany
country: United States
facility: Site US10077 Northeast Urogynecology
state: New York
city: Brooklyn
country: United States
facility: Site US10089 Maimonides Medical Center
state: New York
city: Garden City
country: United States
facility: Site US10026 AccuMed Research Associates
state: New York
city: Kingston
country: United States
facility: Site US10040 Premier Medical Group Of The Hudson Valley
state: New York
city: New York
country: United States
facility: Site US10073 Manhattan Medical Research Practice, PLLC
state: New York
city: New York
country: United States
facility: Site US10249 New York Clinical Trials
state: New York
city: New York
country: United States
facility: Site US10168 Weill Cornell Medical College
state: New York
city: Newburgh
country: United States
facility: Site US10126 Premier Medical Group
state: New York
city: Poughkeepsie
country: United States
facility: Site US10028 Premier Medical Group of the Hudson Valley
state: New York
city: Williamsville
country: United States
facility: Site US10593 Upstate Clinical Research Associates LLC
state: New York
city: Concord
country: United States
facility: Site US10076 Carolina Clinical Trials
state: North Carolina
city: Raleigh
country: United States
facility: Site US10129 PMG Research of Raleigh
state: North Carolina
city: Raleigh
country: United States
facility: Site US10549 Associated Urologists of North Carolina
state: North Carolina
city: Winston-Salem
country: United States
facility: Site US10062 Piedmont Medical Research
state: North Carolina
city: Cleveland
country: United States
facility: Site US10050 Rapid Medical Research, Inc.
state: Ohio
city: Lyndhurst
country: United States
facility: Site US10033 Ohio Clinical Research
state: Ohio
city: Wadsworth
country: United States
facility: Site US10067 Family Practice Center of Wadsworth
state: Ohio
city: West Chester
country: United States
facility: Site US10551 The Christ Hospital
state: Ohio
city: Oklahoma City
country: United States
facility: Site US10109 Lynn Health Science Institute
state: Oklahoma
city: Medford
country: United States
facility: Site US10541 Sunstone Medical Research
state: Oregon
city: Bala-Cynwyd
country: United States
facility: Site US10008 Urologic Consultants of Southeastern Pennsylvania
state: Pennsylvania
city: Lancaster
country: United States
facility: Site US10045 Lancaster Urology
state: Pennsylvania
city: Philadelphia
country: United States
facility: Site US10017 Philadelphia Clinical Research, LLC
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Site US10167 University of Pittsburgh Medical Center
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Site US10250 Preferred Primary Care Physicians Inc.
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Site US10248 Preferred Primary Care Physicians, Inc
state: Pennsylvania
city: Uniontown
country: United States
facility: Site US10063 Preferred Primary Care Physician Research
state: Pennsylvania
city: West Reading
country: United States
facility: Site US10012 Advanced Clinical Concepts
state: Pennsylvania
city: Charleston
country: United States
facility: Site US10166 Medical University of South Carolina
state: South Carolina
city: Greer
country: United States
facility: Site US10094 University Medical Group
state: South Carolina
city: Mount Pleasant
country: United States
facility: Site US10046 Coastal Carolina Research Center
state: South Carolina
city: Mount Pleasant
country: United States
facility: Site US10079 PMG Research of Charleston, LLC
state: South Carolina
city: Myrtle Beach
country: United States
facility: Site US10117 Carolina Urologic Research Center
state: South Carolina
city: Simpsonville
country: United States
facility: Site US10023 Hillcrest Clinical Research, LLC
state: South Carolina
city: Summerville
country: United States
facility: Site US10101 Palmetto Clinical Research
state: South Carolina
city: Kingsport
country: United States
facility: Site US10006 Holston Medical Group
state: Tennessee
city: Austin
country: United States
facility: Site US10084 Dynamed Clinical Research of Austin,LLC dba DM Clinical Resc
state: Texas
city: Carrollton
country: United States
facility: Site US10066 Texas Urology PA
state: Texas
city: Corpus Christi
country: United States
facility: Site US10065 Advanced Research Associates
state: Texas
city: Houston
country: United States
facility: Site US10085 Centex Studies, Inc.
state: Texas
city: Houston
country: United States
facility: Site US10108 Clinical Trial Network
state: Texas
city: Houston
country: United States
facility: Site US10219 Methodist Urology Associates
state: Texas
city: Houston
country: United States
facility: Site US10093 Pioneer Research Solutions, Inc.
state: Texas
city: Hurst
country: United States
facility: Site US10090 Protenium Clinical Research, LLC
state: Texas
city: San Antonio
country: United States
facility: Site US10105 Clinical Trials of Texas
state: Texas
city: San Antonio
country: United States
facility: Site US10111 Clinical Trials of Texas
state: Texas
city: Sandy
country: United States
facility: Site US10092 Physicians' Research Options/Salt Lake Women's Center
state: Utah
city: Richmond
country: United States
facility: Site US10032 National Clinical Research Inc.
state: Virginia
city: Virginia Beach
country: United States
facility: Site US10064 The Group for Women
state: Virginia
city: Virginia Beach
country: United States
facility: Site US10083 Urology of Virginia, PLLC.
state: Virginia
city: Burien
country: United States
facility: Site US10013 Seattle Urology Research Center
state: Washington
city: Mountlake Terrace
country: United States
facility: Site US10004 Integrity Medical Research, LLC
state: Washington
city: Seattle
country: United States
facility: Site US10155 Seattle Women's Health, Research, Gynecology
state: Washington
city: Walla Walla
country: United States
facility: Site US10135 Walla Walla Clinic
state: Washington
city: Buenos Aires
country: Argentina
facility: Site AR54005 IUBA - Instituto Urologico de Buenos Aires
city: Buenos Aires
country: Argentina
facility: Site AR54003 Hospital Italiano de Buenos Aires
city: Buenos Aires
country: Argentina
facility: Site AR54006 Hospital Italiano de Buenos Aires
city: Ciudad Autónoma Buenos Aires
country: Argentina
facility: Site AR54001 CDU - Centro de Urología
city: Rosario Provincia De Santa Fe
country: Argentina
facility: Site AR54004 Instituto de Investigaciones Clnicas Rosario
city: Ballarat
country: Australia
facility: Site AU61026 Ballarat Urology
city: Brisbane
country: Australia
facility: Site AU61022 Brisbane South Clinical Research Centre
city: Broadmeadow
country: Australia
facility: Site AU61005 Hunter Clinical Research
city: Daw Park
country: Australia
facility: Site AU61015 Repatriation General Hospital
city: Footscray
country: Australia
facility: Site AU61025 Western Health
city: Malvern
country: Australia
facility: Site AU61012 Cabrini Hospital
city: Nambour
country: Australia
facility: Site AU61010 Nambour General Hospital
city: Parkville
country: Australia
facility: Site AU61002 The Royal Womens Hospital
city: Perth
country: Australia
facility: Site AU61004 Keogh Institute for Medical Research
city: Randwick
country: Australia
facility: Site AU61007 Prince of Wales Hospital
city: Richmond
country: Australia
facility: Site AU61008 Epworth Healthcare
city: Sherwood
country: Australia
facility: Site AU61019 AusTrialsSherwood
city: Sydney
country: Australia
facility: Site AU61017 Healthpac Medical Centre
city: Sydney
country: Australia
facility: Site AU61021 Royal Hospital for Women
city: Wollongong
country: Australia
facility: Site AU61011 Illawarra Health and Medical Research Institute
city: Gent
country: Belgium
facility: Site BE32004 Gent University Hospital
city: Leuven
country: Belgium
facility: Site BE32011 Universitaire Ziekenhuizen Leuven
city: Roeselare
country: Belgium
facility: Site BE32014 Hart Ziekenhuis
city: Sint-Truiden
country: Belgium
facility: Site BE32012 Sint-Trudo Ziekenhuis, Campus Sint Jozef/Sint-Anna
city: Pleven
country: Bulgaria
facility: Site BG35904 University Hospital (UMHAT) - George Stranski
city: Plovdiv
country: Bulgaria
facility: Site BG35908 MHAT Plovdiv AD
city: Ruse
country: Bulgaria
facility: Site BG35902 MHAT Ruse
city: Sofia
country: Bulgaria
facility: Site BG35905 MHAT Alexandrovska Hospital
city: Sofia
country: Bulgaria
facility: Site BG35903 MHATEM Pirogov
city: Varna
country: Bulgaria
facility: Site BG35906 UMHAT Varna
city: Veliko Tarnovo
country: Bulgaria
facility: Site BG35910 MHAT
city: Edmonton
country: Canada
facility: Site CA15029 Royal Alexandra Hospital
state: Alberta
city: Edmonton
country: Canada
facility: Site CA15035 Glenrose Rehabilitation Hospital
state: Alberta
city: Vancouver
country: Canada
facility: Site CA15033 Prohealth
state: British Columbia
city: Saint John
country: Canada
facility: Site CA15008 Private Practice
state: New Brunswick
city: Barrie
country: Canada
facility: Site CA15001 The Male/Female Health & Research Centre
state: Ontario
city: Brampton
country: Canada
facility: Site CA15006 Bramalea Medical Centre
state: Ontario
city: Brantford
country: Canada
facility: Site CA15003 Brantford Urology Research
state: Ontario
city: Burlington
country: Canada
facility: Site CA15042 G. Kenneth Jansz Medicine Professional Corporation
state: Ontario
city: Hamilton
country: Canada
facility: Site CA15044 McMaster Institute of Urology
state: Ontario
city: Kingston
country: Canada
facility: Site CA15031 Centre for Applied Urology Research (CAUR)
state: Ontario
city: Kitchener
country: Canada
facility: Site CA15007 Eunoia2 Incorporated
state: Ontario
city: London
country: Canada
facility: Site CA15034 Oxford/Richmond Medical
state: Ontario
city: North York
country: Canada
facility: Site CA15032 Stanley Flax Medical Prof Corp
state: Ontario
city: Toronto
country: Canada
facility: Site CA15013 Sunnybrook Health Sciences Center
state: Ontario
city: Toronto
country: Canada
facility: Site CA15004 Primehealth Clinical Research
state: Ontario
city: Toronto
country: Canada
facility: Site CA15002 Toronto Western Hospital
state: Ontario
city: Drummondville
country: Canada
facility: Site CA15026 Rhodin Recherche Clinique
state: Quebec
city: Granby
country: Canada
facility: Site CA15015 Recherches Cliniques Theradev, Inc.
state: Quebec
city: Greenfield Park
country: Canada
facility: Site CA15021 Urology South Shore Research
state: Quebec
city: Laval
country: Canada
facility: Site CA15030 UroLaval
state: Quebec
city: Montreal
country: Canada
facility: Site CA15040 RechercheGCP Research
state: Quebec
city: Montreal
country: Canada
facility: Site CA15020 Diex Research Montreal
state: Quebec
city: Point-Claire
country: Canada
facility: Site CA15010 Ultra Med Research, Inc.
state: Quebec
city: Sherbrooke
country: Canada
facility: Site CA15027 Diex Research Sherbrooke Inc
state: Quebec
city: St-Romuald
country: Canada
facility: Site CA15039 Pro-recherche
state: Quebec
city: Quebec
country: Canada
facility: Site CA15025 Clinique RSF Inc.
city: Fuzhou
country: China
facility: Site CN86017 Affiliated Union Hospital of Fujian Medical Uni.
state: Fujian
city: Beijing
country: China
facility: Site CN86025 Beijing Friendship Hospital
city: Beijing
country: China
facility: Site CN86009 Peking University 3rd Hospital
city: Beijing
country: China
facility: Site CN86013 Beijing Hospital
city: Changchun
country: China
facility: Site CN86014 The First Hospital Bethune of Jilin University
city: Changsha
country: China
facility: Site CN86002 Changsha Central Hospital
city: Chengdu
country: China
facility: Site CN86028 General Hospital of Chengdu Military Region of PLA
city: Chongqing
country: China
facility: Site CN86029 Southwest Hospital (Chongqing)
city: Guangzhou
country: China
facility: Site CN86016 Guangzhou First People's Hospital
city: Lan Zhou
country: China
facility: Site CN86027 Second Hospital of Lanzhou University
city: Lanzhou
country: China
facility: Site CN86030 Lanzhou University First Hospital
city: Nanchang
country: China
facility: Site CN86020 The First Affiliated Hospital of NanChang Univers
city: Nanjing
country: China
facility: Site CN86023 Nanjing First Hospital
city: Shanghai
country: China
facility: Site CN86021 HuaDong Hosipital Affiliated to Fudan University
city: Shanghai
country: China
facility: Site CN86003 Shanghai Renji Hospital
city: Shanghai
country: China
facility: Site CN86012 The Fifth People's Hospital of Shanghai
city: Suzhou
country: China
facility: Site CN86011 The Second Affiliated Hospital of Soochow Universi
city: Suzhou
country: China
facility: Site CN86010 1st Affiliated Hosptital of Suchow University
city: Wenzhou
country: China
facility: Site CN86026 The First Affiliated Hospital of Wenzhou Medical C
city: Wuhan
country: China
facility: Site CN86022 Tongji Hospital, Tongji Medical College of Hust
city: Wuhan
country: China
facility: Site CN86015 Zhongnan Hospital of Wuhan University
city: Wuxi
country: China
facility: Site CN86018 Wuxi People's Hospital
city: Medellin
country: Colombia
facility: Site CO57003 Hospital Pablo Tobón Uribe
state: Antioquia
city: Medellin
country: Colombia
facility: Site CO57004 Instituto de Coloproctologia ICO SAS
city: Brno
country: Czechia
facility: Site CZ42015 Centrum ambulantni gynekologie a primarni pece
city: Hradec Kralove
country: Czechia
facility: Site CZ42003 SANUS
city: Hradec Kralove
country: Czechia
facility: Site CZ42001 Fakultni Nemocnice Hradec Kralove
city: Jihlava
country: Czechia
facility: Site CZ42002 Hospital Jihlava
city: Novy Jicin
country: Czechia
facility: Site CZ42011 Hospital Novy Jicin
city: Olomouc
country: Czechia
facility: Site CZ42010 G-centrum Olomouc S.R.O.
city: Ostrava
country: Czechia
facility: Site CZ42014 Private Practice
city: Plzen
country: Czechia
facility: Site CZ42005 Research Site s.r.o.
city: Praha 4
country: Czechia
facility: Site CZ42007 Uro-Santé/Nová Brumlovka
city: Sternberk
country: Czechia
facility: Site CZ42013 Urology Clinic
city: Uherske Hradiste
country: Czechia
facility: Site CZ42009 Hospital Uherské Hradiště a.s.
city: Usti nad Labem
country: Czechia
facility: Site CZ42006 Private Practice
city: Aalborg
country: Denmark
facility: Site DK45012 Aalborg Sygehus Nord
city: Aarhus
country: Denmark
facility: Site DK45013 University Hospital of Aarhus, Skejby
city: Parnu
country: Estonia
facility: Site EE37201 Parnu Hospital
city: Tallinn
country: Estonia
facility: Site EE37205 West Tallinn Central Hospital
city: Tartu
country: Estonia
facility: Site EE37202 Tartu University Hospital
city: Kouvola
country: Finland
facility: Site FI35801 Kouvolan Lääkäriasema
city: Oulu
country: Finland
facility: Site FI35803 Oulu University Hospital
city: Vantaa
country: Finland
facility: Site FI35802 Meilahti Hospital
city: Colmar Cedex
country: France
facility: Site FR33007 Centre Hospitalier Louis Pasteur
city: Dijon
country: France
facility: Site FR33010 CHU Hopital du Bocage
city: Nantes Cedex 1
country: France
facility: Site FR33008 CHU Nantes
city: Nimes Cedex
country: France
facility: Site FR33002 CHU Carémeau
city: Paris Cedex 20
country: France
facility: Site FR33001 Hopital Tenon
city: Paris Cedex 20
country: France
facility: Site FR33024 Hopital Tenon
city: Paris
country: France
facility: Site FR33013 Hopital Saint Louis
city: Pierre Benite Cedex
country: France
facility: Site FR33011 Centre Hospitalier Lyon Sud
city: Suresnes
country: France
facility: Site FR33012 Hopital Foch
city: Tours Cedex 9
country: France
facility: Site FR33005 Hopital Bretonneau
city: Bad Ems
country: Germany
facility: Site DE49008 Private Practice
city: Bergisch Gladbach
country: Germany
facility: Site DE49031 Urologisches Zentrum Refrath
city: Bonn
country: Germany
facility: Site DE49033 Universitsy Clinic Bonn
city: Duisburg
country: Germany
facility: Site DE49002 Private Practice
city: Duisburg
country: Germany
facility: Site DE49032 Urologicum Duisburg
city: Ganderkesee
country: Germany
facility: Site DE49010 Private Practice
city: Halle (Saale)
country: Germany
facility: Site DE49011 Private Practice
city: Leipzig
country: Germany
facility: Site DE49013 Private Practice
city: Lutherstadt Eisleben
country: Germany
facility: Site DE49003 Private Practice
city: Munich
country: Germany
facility: Site DE49034 LMU Muenchen
city: Neustadt I. Sachsen
country: Germany
facility: Site DE49001 Private Practice
city: Rostock
country: Germany
facility: Site DE49026 Zentrum fuer Onkologie und Urologie Rostock
city: Sangerhausen
country: Germany
facility: Site DE49014 Private Practice
city: Athens
country: Greece
facility: Site GR30009 Aretaieio/Maginio
city: Hong Kong
country: Hong Kong
facility: Site HK85204 The Chinese Uni of HK, Prince of Wales Hospital
city: Kowloon
country: Hong Kong
facility: Site HK85201 Kwong Wah Hospital
city: Shatin
country: Hong Kong
facility: Site HK85203 The Chinese Uni of HK, Prince of Wales Hospital
city: Csongrád
country: Hungary
facility: Site HU36003 Dr.Szarka Ödön Kistérségi Egészségügyi Szolgáltató Kft
city: Kecskemet
country: Hungary
facility: Site HU36007 Mediroyal Prevention Center
city: Pecs
country: Hungary
facility: Site HU36005 Uro-clin Ltd
city: Sopron
country: Hungary
facility: Site HU36013 Sopron Erzsébet Hospital
city: Szentes
country: Hungary
facility: Site HU36001 Donatella 99BT
city: Veszprém
country: Hungary
facility: Site HU36012 Veszprém County Cholnoky Ferenc Hospital
city: Ancona
country: Italy
facility: Site IT39022 Azienda Ospedale Umberto I (Ancona)
city: Avellino
country: Italy
facility: Site IT39007 Azienda Ospedaliera San Giuseppe Moscati
city: Latina
country: Italy
facility: Site IT39001 U.O. Dip. di Neuro-Urologia; Univ. di Roma La Sapienza
city: Milano
country: Italy
facility: Site IT39020 Ospedale San Raffaele IRCCS, U.O. di Ginecologia e Ostetricia, Unità Funzionale di Uroginecologia
city: Milan
country: Italy
facility: Site IT39003 Ospedale San Raffaele
city: Bucheon-Si
country: Korea, Republic of
facility: Site KR82014 Soon Chun Hyang University Hospital
city: Busan
country: Korea, Republic of
facility: Site KR82006 Dong-A University Medical Center
city: Busan
country: Korea, Republic of
facility: Site KR82016 Pusan National University Hospital
city: Cheongju-si
country: Korea, Republic of
facility: Site KR82024 Chungbuk National University Hospital
city: Daegu
country: Korea, Republic of
facility: Site KR82032 Kyungpook National University Hospital
city: Daegu
country: Korea, Republic of
facility: Site KR82005 Yeungnam University Hospital
city: Daegu
country: Korea, Republic of
facility: Site KR82029 Daegu Catholic Univ. Medical Center
city: Daejeon
country: Korea, Republic of
facility: Site KR82019 Chungnam National University Hospital
city: Daejeon
country: Korea, Republic of
facility: Site KR82011 Eulji University Hospital
city: Gwangju
country: Korea, Republic of
facility: Site KR82031 Chonnam National University Hospital
city: Iksan -Si
country: Korea, Republic of
facility: Site KR82009 Wonkwang University Hospital
city: Incheon
country: Korea, Republic of
facility: Site KR82023 Gachon University Gil Hospital
city: Jeonju-si
country: Korea, Republic of
facility: Site KR82010 Chonbuk National University Hospital
city: Seongnam-si
country: Korea, Republic of
facility: Site KR82025 Seoul National University Bundang Hospital
city: Seoul
country: Korea, Republic of
facility: Site KR82021 Cheil General Hospital & Women's Healthcare Center
city: Seoul
country: Korea, Republic of
facility: Site KR82020 Seoul National University Hospital
city: Seoul
country: Korea, Republic of
facility: Site KR82030 Severance Hospital
city: Seoul
country: Korea, Republic of
facility: Site KR82013 Hallym University Kangdong Sacred Heart Hospital
city: Seoul
country: Korea, Republic of
facility: Site KR82017 Kyung Hee University Medical Center
city: Seoul
country: Korea, Republic of
facility: Site KR82002 Samsung Medical Center
city: Seoul
country: Korea, Republic of
facility: Site KR82008 Gangnam Severance Hospital
city: Seoul
country: Korea, Republic of
facility: Site KR82015 Korea University Medical Center
city: Seoul
country: Korea, Republic of
facility: Site KR82001 Seoul Saint Mary's Hospital
city: Seoul
country: Korea, Republic of
facility: Site KR82003 Asan Medical Center
city: Seoul
country: Korea, Republic of
facility: Site KR82012 Konkuk University Medical Center
city: Suwon-si
country: Korea, Republic of
facility: Site KR82004 Ajou University Hospital
city: Liepaja
country: Latvia
facility: Site LV37102 Private Practice
city: Olaine
country: Latvia
facility: Site LV37103 Health Centre "Olaine"
city: Riga
country: Latvia
facility: Site LV37105 P.Stradins Clinical University Hospital
city: Kaunas
country: Lithuania
facility: Site LT37008 Kaunas 2nd Clinical Hospital
city: Kaunas
country: Lithuania
facility: Site LT37004 KHospital of Lithuanian University of Health Science
city: Kaunas
country: Lithuania
facility: Site LT37011 Saules Family Medicine Centre
city: Klaipeda
country: Lithuania
facility: Site LT37012 Klaipeda University Hospital
city: Vilnius
country: Lithuania
facility: Site LT37005 Public Institution Vilnius City University Hospital
city: Vilnius
country: Lithuania
facility: Site LT37010 Public Institution Vilnius City University Hospital
city: Vilnius
country: Lithuania
facility: Site LT37003 Family Medical Centre Seimos gydytojas
city: Vilnius
country: Lithuania
facility: Site LT37007 Vilnius University Hospital Santariskiu Klinikos
city: Vilnius
country: Lithuania
facility: Site LT37009 Clinics Privatus gydytojas
city: Georgetown
country: Malaysia
facility: Site MY60006 Hospital Pulau Pinang
city: Kuala Lumpur
country: Malaysia
facility: Site MY60001 Hospital Kuala Lumpur
city: Kuala Lumpur
country: Malaysia
facility: Site MY60004 University Malaya Medical Centre
city: Kuala Lumpur
country: Malaysia
facility: Site MY60005 Universiti Kebangsaan Malaysia Medical Centre
city: Kuching
country: Malaysia
facility: Site MY60003 Hospital Ummum Sarawak
city: Petaling Jaya
country: Malaysia
facility: Site MY60002 Sime Darby Medical Centre
city: Durango
country: Mexico
facility: Site MX52004 Consultorio de Especialidad en Urologia
city: Guadalajara
country: Mexico
facility: Site MX52001 Centro de Investigacin Basica y Clnica
city: Mexico City
country: Mexico
facility: Site MX52003 Clinstile, Sociedad Anonima de Capital Variable
city: Monterrey
country: Mexico
facility: Site MX52002 Accelerium Clinical Research/ Hospital San Jorge
city: Amsterdam
country: Netherlands
facility: Site NL31002 Academic Medical Center (AMC)
city: Enschede
country: Netherlands
facility: Site NL31006 Medisch Spectrum Twente
city: Nijmegen
country: Netherlands
facility: Site NL31005 Canisius-Wilhelmina Ziekenhuis
city: Sneek
country: Netherlands
facility: Site NL31010 Antonius Ziekenhuis Sneek
city: Utrecht
country: Netherlands
facility: Site NL31001 University Medical Centre Utrecht
city: Auckland
country: New Zealand
facility: Site NZ64004 John A Tuckey Ltd Ascot Central
city: Christchurch
country: New Zealand
facility: Site NZ64001 Canterbury Urology Research Trust
city: Hamilton
country: New Zealand
facility: Site NZ64005 Waikato Urology Research Limited
city: Nelson
country: New Zealand
facility: Site NZ64002 Roundhay Medical Centre
city: Tauranga
country: New Zealand
facility: Site NZ64003 Tauranga Urology Research Ltd
city: Whangarei
country: New Zealand
facility: Site NZ64006 Cardinal Point Specialist Centre
city: Hamar
country: Norway
facility: Site NO47006 M3 Helse AS
city: Lierskogen
country: Norway
facility: Site NO47008 Norsk Helseklinikk (Heiaklinikken)
city: Ålesund
country: Norway
facility: Site NO47007 Medi3 Clinic AS, Ålesund
city: La Victoria
country: Peru
facility: Site PE51006 Hospital Nacional Guillermo Almenara Irigoyen EsSalud
state: Lima
city: San Isidro
country: Peru
facility: Site PE51007 Clínica Anglo Americana
state: Lima
city: Lima
country: Peru
facility: Site PE51001 Instituto de Ginecologia y Reproduccion
city: Lima
country: Peru
facility: Site PE51002 Clinica San Borja
city: Lima
country: Peru
facility: Site PE51004 Clinica San Pablo
city: Lima
country: Peru
facility: Site PE51005 Hospital Nacional Hipolito Unanue
city: Bacolod City
country: Philippines
facility: Site PH63008 Dr. Pablo O. Torre Memorial Hospital
city: Davao City
country: Philippines
facility: Site PH63005 Davao Doctor's Hospital
city: Davao City
country: Philippines
facility: Site PH63010 Davao Doctor's Hospital
city: Manila
country: Philippines
facility: Site PH63003 University of Santo Tomas Hospital (USTH)
city: Manila
country: Philippines
facility: Site PH63009 Chinese General Hospital and Medical Center
city: Quezon City
country: Philippines
facility: Site PH63004 East Avenue Medical Center
city: Bialystok
country: Poland
facility: Site PL48018 Gastromed
city: Chorzow
country: Poland
facility: Site PL48013 Urovita Ltd.
city: Gdynia
country: Poland
facility: Site PL48014 Synexus Polska
city: Lodz
country: Poland
facility: Site PL48004 NZOZ Szpital Sw.Rodziny Centrum Medyczne
city: Lublin
country: Poland
facility: Site PL48010 Nzoz Novita
city: Myslowice
country: Poland
facility: Site PL48011 Nzoz Centrum Urologiczne sp. z o.o.
city: Opole
country: Poland
facility: Site PL48016 Prywatny Gabinet Urologiczny
city: Piaseczno
country: Poland
facility: Site PL48005 HEUREKA Hanna Szalecka
city: Warsaw
country: Poland
facility: Site PL48012 Military Institute of Medicine
city: Warsaw
country: Poland
facility: Site PL48003 CSKMSW
city: Warszawa
country: Poland
facility: Site PL48001 Specjalistyczny Gabinet Lekarski
city: Wrocław
country: Poland
facility: Site PL48019 Synexus Polska sp. z o. o.
city: Brasov
country: Romania
facility: Site RO40015 Spitaul Clinic Judetean de Urgenta Brasov
city: Bucuresti
country: Romania
facility: Site RO40004 Spitalul Clinic de Urgenta Sfantul Ioan
city: Bucuresti
country: Romania
facility: Site RO40001 Spiatlul Clinic Th. Burghele
city: Bucuresti
country: Romania
facility: Site RO40005 Spiatlul Clinic Th. Burghele
city: Cluj-Napoca
country: Romania
facility: Site RO40014 E-URO Cabinet
city: Iasi
country: Romania
facility: Site RO40007 Spital Clinic
city: Sibiu
country: Romania
facility: Site RO40010 Spitalul Clinic Judetan de Urgenta Sibiu
city: Timisoara
country: Romania
facility: Site RO40002 Spitalul Clinic Judetean de Urgenta Timisoara
city: Kazan
country: Russian Federation
facility: Site RU70015 LLC Clinical Research Medical Complex
city: Penza
country: Russian Federation
facility: Site RU70023 Penza Regional Clinical Hospatal n. a. N.N. Burdenko
city: Saint Petersburg
country: Russian Federation
facility: Site RU70019 City Multidisciplinary Hospital No. 2
city: Saint Petersburg
country: Russian Federation
facility: Site RU70002 Pavlov St. Petersburg State Medical University
city: Saint Petersburg
country: Russian Federation
facility: Site RU70022 St. Petersburg State Public Health Institution
city: St. Petersburg
country: Russian Federation
facility: Site RU70014 OOO Hospital Orkli
city: Ufa
country: Russian Federation
facility: Site RU70018 Bashkirsky State Medical University of Roszdrav
city: Singapore
country: Singapore
facility: Site SG65001 National University Hospital
city: Singapore
country: Singapore
facility: Site SG65002 Singapore General Hospital
city: Singapore
country: Singapore
facility: Site SG65003 KK Women's and Children's Hospital
city: Bratislava
country: Slovakia
facility: Site SK42105 Ruzinovska poliklinika a.s.
city: Kosice
country: Slovakia
facility: Site SK42107 Zeleznicne zdravotnictvo Kosice, s.r.o.
city: Kosice
country: Slovakia
facility: Site SK42101 Andrologicka a Urologicka Ambulancia
city: Nitra
country: Slovakia
facility: Site SK42103 UroExam s.r.o.
city: Poprad
country: Slovakia
facility: Site SK42108 BrenCare, s. r. o.
city: Presov
country: Slovakia
facility: Site SK42104 Urology Outpatient Department
city: Trencin
country: Slovakia
facility: Site SK42106 Private Urological Care Center
city: Trencin
country: Slovakia
facility: Site SK42102 CeGys, s.r.o.
city: Murska Sobota
country: Slovenia
facility: Site SI38604 General Hospital Murska Sobota
city: Novo Mesto
country: Slovenia
facility: Site SI38602 General Hospital Novo Mesto
city: Cape Town
country: South Africa
facility: Site ZA27005 Grootte Schuur Hospital
city: Centurion
country: South Africa
facility: Site ZA27001 Private Practice
city: Durban
country: South Africa
facility: Site ZA27006 Parklands Hospital
city: Meyerspark
country: South Africa
facility: Site ZA27013 Synexus Clinical Research SA (Pty) Ltd
city: Paarl
country: South Africa
facility: Site ZA27007 Paarl Medical Centre
city: Roodepoort
country: South Africa
facility: Site ZA27002 Mayo Clinic
city: Coslada
country: Spain
facility: Site ES34010 Hospital del Henares
city: Esplugues De Llobregat-Barcelo
country: Spain
facility: Site ES34024 Hospital San Juan de Dios
city: Getafe (Madrid)
country: Spain
facility: Site ES34001 Hospital Universitario de Getafe
city: Madrid
country: Spain
facility: Site ES34006 Hospital San Rafael
city: Madrid
country: Spain
facility: Site ES34004 Hospital Infanta Leonor
city: Madrid
country: Spain
facility: Site ES34015 Hospital 12 de Octubre
city: Madrid
country: Spain
facility: Site ES34009 Hospital Universitario La Paz
city: Madrid
country: Spain
facility: Site ES34005 Hospital de Fuenlabrada
city: Sevilla
country: Spain
facility: Site ES34003 Hospital Universitario Nuestra Señora de Valme
city: Sevilla
country: Spain
facility: Site ES34007 Hospital Virgen del Rocio
city: Valencia
country: Spain
facility: Site ES34002 H. U. Politecnico La Fe
city: Boras
country: Sweden
facility: Site SE46007 Ladulaas Clinical Studies
city: Helsingborg
country: Sweden
facility: Site SE46025 Pharmasite
city: Malmö
country: Sweden
facility: Site SE46005 Center för Läkemedelsstudier
city: Stockholm
country: Sweden
facility: Site SE46016 Citydiabetes - Stockholm
city: Stockholm
country: Sweden
facility: Site SE46008 Bragée Medect AB
city: Stockholm
country: Sweden
facility: Site SE46012 Karolinska University Hospital Huddinge
city: Stockholm
country: Sweden
facility: Site SE46003 Danderyds Hospital
city: Uppsala
country: Sweden
facility: Site SE46009 Encia AB, Uppsala Hälsomottagning
city: Vällingby
country: Sweden
facility: Site SE46017 S3 Clinical Research Centers
city: Taichung
country: Taiwan
facility: Site TW88605 Taichung Veteran General Hospital
city: Taichung
country: Taiwan
facility: Site TW88611 Chung Shan Medical University Hospital
city: Tainan
country: Taiwan
facility: Site TW88612 Chi Mei Medical Center, Yong Kang
city: Taipei
country: Taiwan
facility: Site TW88614 Tri-Service General Hospital
city: Bangkok
country: Thailand
facility: Site TH66002 Chulalongkorn Hospital
city: Bangkok
country: Thailand
facility: Site TH66008 Phramongkutklao Hospital
city: Bangkok
country: Thailand
facility: Site TH66005 Siriraj Hospital
city: Chiang Mai
country: Thailand
facility: Site TH66010 Maharaj Nakorm Chiangmai Hosp
city: Hat Yai
country: Thailand
facility: Site TH66006 Songklanagarind Hospital, Prince of Songkla University
city: Khon Kaen
country: Thailand
facility: Site TH66009 Srinagarind Hospital
city: Pathum Thani
country: Thailand
facility: Site TH66007 Thammasat University Hospital
city: Ratchathewi
country: Thailand
facility: Site TH66011 Ramathibodi Hospital
city: Ankara
country: Turkey
facility: Site TR90019 Ankara University Medical Faculty Ibni Sina Hospital
city: Bursa
country: Turkey
facility: Site TR90013 Uludag University Faculty of Medicine
city: Denizli
country: Turkey
facility: Site TR90001 Pamukkale University Faculty of Medicine
city: Istanbul
country: Turkey
facility: Site TR90017 Bilim University Sisli Florence Nightingale Hospital
city: Chernigov
country: Ukraine
facility: Site UA38002 City Hospital No 2
city: Chernivtsi
country: Ukraine
facility: Site UA38015 Regional Municipal Institution, Urology Department
city: Dnipropetrovsk
country: Ukraine
facility: Site UA38013 Dnipropetrovsk State Medical Academy, Mechnikov Dnipropetrov
city: Kharkiv
country: Ukraine
facility: Site UA38006 Shapoval Regional Clinical Centre of Urology and Nephrology
city: Kiev
country: Ukraine
facility: Site UA38007 Central Outpatient Hospital of Deanyanskyy Distric
city: Kyiv
country: Ukraine
facility: Site UA38003 Urology Dpt of Kyiv City Clinical Hospital #3
city: Kyiv
country: Ukraine
facility: Site UA38010 Academy of Medical Sciences of Ukraine
city: Uzhorod
country: Ukraine
facility: Site UA38014 Uzhgorod City Polyclinic
city: Vinnytsya
country: Ukraine
facility: Site UA38004 Vinnitsa Endocrinology Dispens
city: Zaporizhzhya
country: Ukraine
facility: Site UA38008 Medical Academy of Postgraduate Education, Urology Clinic
city: Garston
country: United Kingdom
facility: Site GB44009 Sheepcot Medical Centre
state: Watfort
city: Crewe
country: United Kingdom
facility: Site GB44003 Leighton Hospital
city: Gillingham
country: United Kingdom
facility: Site GB44021 Medway Hospital
city: Harrow
country: United Kingdom
facility: Site GB44005 North West London Hosp Menopause Clinic
city: Leeds
country: United Kingdom
facility: Site GB44024 St James's University Hospital
city: London
country: United Kingdom
facility: Site GB44025 Kings College Hospital
city: Plymouth
country: United Kingdom
facility: Site GB44006 Derriford Hospital
city: Reading
country: United Kingdom
facility: Site GB44022 The Royal Berkshire Hospital
city: Sheffield
country: United Kingdom
facility: Site GB44001 Royal Hallamshire Hospital
Study officials:
affiliation: Astellas Pharma Europe B.V.
name: Medical Director
role: STUDY_DIRECTOR
References: