Clinical trial NCT05185700: Symptoms ,Signs and Complications That Appear After Infection With Covid 19 Virus
Official title: Post Covid 19 Syndrome
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: COVID-19
Keywords: post covid-19
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2022-01-11
Enrollment: 180
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: This prospective study will be conducted on 175 patients who were previously diagnosed as covid-19. A written consent will be obtained from the patient or from his first degree-relative.

Brief summary: 1. Raise awareness for persistent post-COVID syndrome (PPCS).
2. Rising tide of physical and psychological disabilities that have been described in post-COVID patients.

Detailed description: Since SARS-CoV-2 infection was recognised in late 2019, the academic and clinical emphasis has been on respiratory manifestations .

Post-COVID syndrome appears to be a multisystem disease, occurring even after a relatively mild acute illness. Increasing evidence exists for direct multiorgan effects, and indirect effects on other organ systems and disease processes, such as cardiovascular diseases and cancers, through changes in healthcare delivery and patient behaviors . So, the long term effects of covid-19 on individuals and health systems are becoming clear, investigation across organ systems is urgently needed. Long covid, or post-covid syndrome, is not one condition, and is defined by the National Institute for Health and Care Excellence (NICE) as "signs and symptoms that develop during or after an infection consistent with covid-19 which continue for more than 12 weeks and are not explained by an alternative diagnosis . NICE guidelines recommend referral to post-covid syndrome assessment clinics if post covid symptoms persist for 6-12 weeks . Pre-existing conditions and risk factors are predictors of acute covid-19 outcomes (such as admission to the intensive care unit and mortality, but the epidemiology of postcovid syndrome has been less well defined . Because of the unclear medium and long term pathophysiology across organ systems. When post-covid syndrome clinics are established, characterization of the epidemiology of the disease will help with appropriate diagnosis, care, public health interventions and policy, and resource planning. So, further research is highly indicated.

Eligibility criteria: Inclusion Criteria:

* patient diagnosed as covid-19.
* Presence of post covid-19 symptoms.

Exclusion Criteria:

* Patient refusal.
* Patient less than 18 years.

Primary outcomes:
measure: Identifying post covid -19 respiratory manifestations.
timeFrame: 1 year
Secondary outcomes:
measure: identifying other post covid -19 manifestations.
timeFrame: 1 year
Other outcomes:
Locations:
Study officials:
affiliation: assuit university hospital
name: Rafaat T El-Sokry, professor
role: STUDY_DIRECTOR
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