Clinical trial NCT04690959: Comparative Effects of Tensioning and Sliding Neural Mobilization on Nerve Root Function
Official title: Comparative Effects of Tensioning and Sliding Neural Mobilization on Nerve Root Function :Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Physical and Rehabilitation Medicine
Keywords: Randomized controlled trial
Neurodynamics
evoked potential
somatosensory
Lead sponsor: University of Sharjah
Sponsor class: OTHER
First posted: 2020-12-31
Enrollment: 90
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: A prospective, parallel-group, randomized clinical trial participants will be randomly assigned to the control group or one of the 2 intervention groups. One group received neural gliding mobilization and the other neural tensioning mobilization, both targeting the median nerve
Primary purpose: TREATMENT

Brief summary: the current study will try to answer the question: Is it theoretically possible, that increased longitudinal stress on nerve root from sliding or tensioning intervention may subtly affect the neural function? Our hypothesis is that tensioning and sliding, differently affect the neural function.

Detailed description: A prospective, parallel randomized, controlled study will be conducted at a research laboratory of our University. Participant recruitment will begin following approval from the Ethics Committee .The patients will participate in the study after signing an informed consent form prior to data collection.

Per inclusion criteria, subjects will be between 18 and 50 years of age, not currently experiencing any neck or dominant upper extremity symptoms, do not have a history significant for a chronic painful condition, and will not using pain relievers. Prior to participating in any study-related procedures, participants will read and signed an informed consent form approved by the Institutional Review Board.

Participants will be divided into three groups; One group will receive neural gliding mobilization and the other neural tensioning mobilization, both targeting the median nerve.

. the third group will receive sham neural mobilization intervention . Participants were not given information on which neural mobilization technique they were receiving; they were only told that they could receive one of two different neural mobilization techniques. Six sessions will be given every other day for 2 weeks.

Eligibility criteria: Inclusion Criteria:

* not currently experiencing any neck or dominant upper extremity symptoms.
* do not have a history significant for a chronic painful condition.
* do not using pain relievers.

Exclusion Criteria:

* inflammatory joint disease or other systemic pathologies.
* prior history of overt injury and surgery relating to the musculoskeletal system.
* disorder related to the spine and extremities.
* musculoskeletal pain in the last three months.

Primary outcomes:
measure: Change in dermatomal somatosensory evoked potentials
timeFrame: baseline (pre-treatment) , 2 weeks ,through study completion, an average of 1 week
Secondary outcomes:
measure: Change in Skin Sympathetic response
timeFrame: baseline (pre-treatment) , 2 weeks ,through study completion, an average of 1 week
measure: Change in Pressure pain threshold
timeFrame: baseline (pre-treatment) , 2 weeks of treatment and at 1 week following the end of treatment
Other outcomes:
Locations:
city: Sharjah
country: United Arab Emirates
facility: Ibrahim Moustafa
state: United Arab Emirate
city: Sharjah
country: United Arab Emirates
facility: University of Sharjah
Study officials:
affiliation: University of Sharjah
name: Ibrahim Moustafa, associate professor
role: PRINCIPAL_INVESTIGATOR
References: