louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02484365: Preoperative Noninvasive Hemoglobin Monitoring in Pediatric Patients
Official title: The Accuracy of the Noninvasive Hemoglobin Monitoring for Preoperative Evaluation for Pediatric Patients
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Surgery
Keywords: Hemoglobins
Monitoring, Outpatient
Preoperative Period
Pediatrics
Lead sponsor: Chung-Ang University Hosptial, Chung-Ang University College of Medicine
Sponsor class: OTHER
First posted: 2015-06-29
Enrollment: 177
Sex: ALL
Minimum age (years): 1
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: pediatric patients age under 18 years planning to receive elective surgery under general anesthesia people live in South Korea

Brief summary: The preoperative evaluation including sampling blood in pediatric patients is hard to perform. However, the knowledge of the baseline cell blood count is important to prepare unexpected surgical bleeding etc.. The invasive procedure for blood sampling in small children is often failed and sometimes induces iatrogenic blood loss and parent's complaints. The Pulse Co-oximetry (Masimo) is recently developed device which can provide noninvasive hemoglobin value. However, the accuracy is controversial. There are studies in pediatric patients during surgery and in ICU. However, the comparison for preoperative evaluation is not analysed. Therefore, the investigators want to evaluate the accuracy for preoperative preparation in pediatric patients.

Detailed description: There are not enough data comparing the noninvasive hemoglobin and venous hemoglobin in pediatric patients during preoperative period. The investigators will collect the venous sample and the noninvasive hemoglobin data from masimo within 1 hour. Without any additional medication, the patients will visit preanesthetic room and attach the probe of masimo on index finger. The R 20L or R25L will be used based on their weight. The parameter will be stabilized within 2 minutes and the SpHb and perfusion index will be recorded.

Eligibility criteria: Inclusion Criteria:

* ASA class 1,2

Exclusion Criteria:

* Poor peripheral circulation
* Infection or trauma on the sensor contact region

Primary outcomes:
measure: hemoglobin
timeFrame: once, preoperative visit anesthetic office
Secondary outcomes:
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Department of Anesthesiology and Pain Medicine : Chung-Aung University Hospital
Study officials:
affiliation: Chung-Ang University Hosptial, Chung-Ang University College of Medicine
name: Yong-Hee Park
role: PRINCIPAL_INVESTIGATOR
References:
citation: Jung YH, Lee J, Kim HS, Shin SH, Sohn JA, Kim EK, Choi JH. The efficacy of noninvasive hemoglobin measurement by pulse CO-oximetry in neonates. Pediatr Crit Care Med. 2013 Jan;14(1):70-3. doi: 10.1097/PCC.0b013e318260117d.
Clinical trial NCT04290065: Miodural Bridge Stretching in Posture Modification in Professional Footballers
Official title: Efficacy of a Physiotherapy Intervention by Stretching the Miodural Bridge in the Modification of Posture in Professional Soccer Players. A Randomized Clinical Study.
Study type: INTERVENTIONAL
Overall status: WITHDRAWN
Phase: NA
Conditions: Hamstring Injury
Keywords: Hamstring muscle
Soccer
Flexibility
Hip joint
Suboccipital muscles
Lead sponsor: Investigación en Hemofilia y Fisioterapia
Sponsor class: NETWORK
First posted: 2020-02-28
Enrollment: 0
Sex: MALE
Minimum age (years): 18
Maximum age (years): 23
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Fatigue influences the kinematics of the knee. Decreasing the tone of the suboccipital musculature may decrease the tone of the knee flexors. Inhibition of the suboccipital musculature is used to improve ischiosural muscle tension.

The main objective of the study is to evaluate the effectiveness of the stretching of the miodural bridge in the modification of the posture in professional soccer players of 3rd division.

Randomized clinical trial. 30 players will be randomized to the two study groups: experimental (technique of stretching technique of the miodural bridge) and control (without intervention). A blinded evaluator will perform three evaluations: pretreatment, post-treatment and follow-up. The study variables will be: modification of posture and weight distribution (plantar pressure platform). The sample distribution will be calculated using a Kolmogórov-Smirnov analysis. The changes after each evaluation will be analyzed with the t-student test of related samples and through an ANOVA of repeated measures the intra and intersubject effect will be observed. The effect size will be calculated using Cohen's formula.

After stretching the miodural bridge, it is expected to see improvement in posture changes.


Eligibility criteria: Inclusion Criteria:

* Football players
* Male
* From 18 to 23 years old
* That have a federation file in 3rd division in the Region of Murcia
* That you don't have any acute lesions at the time of the study.

Exclusion Criteria:

* Subjects that: present some relevant subacute or chronic pathology that may have a direct impact on the processes or structures related to the study who have neurological problems or related to the vestibular system
* That receive a specific Physiotherapy training on any of the study regions
* Not sign the informed consent document

Primary outcomes:
measure: Change from baseline posture modification after treatment and at month
timeFrame: Screening visit, within the first seven days after treatment and after one month follow-up visit
Secondary outcomes:
measure: Change from baseline modification of the weight distribution after treatment and at month
timeFrame: Screening visit, within the first seven days after treatment and after one month follow-up visit
Other outcomes:
Locations:
city: Madrid
country: Spain
facility: Universidad Europea de Madrid
state: Comunity Of Madrid
Study officials:
References:
Clinical trial NCT05339165: FAMily Factors INvolved in Eating Disorders
Official title: FAMily Factors INvolved in Eating Disorders
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Eating Disorders
Keywords: Eating disorder, anorexia nervosa, bulimia nervosa
Lead sponsor: University Medical Center Goettingen
Sponsor class: OTHER
First posted: 2022-04-21
Enrollment: 600
Sex: ALL
Minimum age (years): 12
Maximum age (years): 59
Standard ages: CHILD
ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Study participants with diagnosed anorexia nervosa or bulimia nervosa according to ICD-10 criteria

Brief summary: This observational study compares parental age and birth order in patients diagnosed with anorexia nervosa and bulimia nervosa.

Detailed description: Study participants are recruited (300 patients for each entity). Healthy subjects without evidence of an eating disorder serve as a control group. Psychometric assessment will include data on pathological eating behavior and general psychological and interpersonal problems.

Outcome measures The SCL-90-R questionnaire is a self-report inventory for adolescents and adults that assesses a wide range of psychological problems and symptoms of psychopathology. The questionnaire consists of 90 items, each of which contributes to one of nine primary symptom dimensions.

The short form of the Inventory of Interpersonal Problems (IIP-C) is used to measure interpersonal problems. This self-report questionnaire contains 64 items assigned to eight subscales.

Eligible candidates are stratified as cases or matched controls as follows:

1. Cases are eligible patients diagnosed with anorexia nervosa or bulimia nervosa (n=300 for each entity) at the time of study inclusion.
2. Controls (100) are healthy subjects of a similar age distribution and from the same study site without the diagnosis of an eating disorder.

Inclusion criteria:

- Age \> 12 and \< 59 years (adolescents and adults).

Exclusion criteria:

* Diagnosed with a malignant disease
* Not fluent in the German language
* Severe mental disorder

Eligibility criteria: Inclusion Criteria:

- Age \> 12 and \< 59 years (adolescents and adults) with either anorexia nervosa or bulimia nervosa.

Exclusion Criteria:

* Diagnosed with a malignant disease
* Not fluent in the German language
* Severe mental disorder

Primary outcomes:
measure: SCL-90-R questionnaire
timeFrame: One day
measure: Short form of the Inventory of Interpersonal Problems (IIP-C)
timeFrame: One day
Secondary outcomes:
Other outcomes:
Locations:
city: Göttingen
country: Germany
facility: University of Göttingen
state: NDS
city: Göttingen
country: Germany
facility: University Medical Center
Study officials:
affiliation: University of Göttingen
name: Thomas Meyer
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04342065: Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery
Official title: Efficacy of Pre-emptive Different Doses of Oral Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Patients Subjected for Elective Lumbar Spine Fixation Surgery: a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
PHASE3
Conditions: Post-Operative Pain
Lead sponsor: South Egypt Cancer Institute
Sponsor class: OTHER
First posted: 2020-04-10
Enrollment: 200
Sex: ALL
Minimum age (years): 21
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The anti-epileptic drugs such as gabapentin and other non-steroidal anti-inflammatory drugs (NSAID) such as celecoxib were used as a part of multimodal analgesia to control such pain. Gabapentin is an anticonvulsant drug that has analgesic effect in post-herpetic neuralgia, diabetic neuropathy, and neuropathic pain. Celecoxib is one of the NSAIDs, that its analgesic effect is reported in various studies by cyclooxygenase-2 (COX-2) inhibitor.

The aim of this randomized double-blinded study was to asses and compare the efficacy of using gabapentin versus celecoxib as a part of multimodal analgesia in perioperative hemodynamic control and pain relief in patients underwent posterior approach lumbar spine disc fixation surgery.


Eligibility criteria: Inclusion Criteria:

* American society of anesthesiologists (ASA) I and II, aged between 21-60 years old scheduled to undergo elective posterior approach lumbar spine disc surgery

Exclusion Criteria:

* Patients with a known sensitivity to celecoxib or pregabalin, psychotic disorder or cognitive impairment, history of drug dependency or substance addiction, history of chronic medical disease, the presence of coagulation disorders or pregnancy, were excluded from the study.

Primary outcomes:
measure: pain control
timeFrame: Change from Baseline Visual Analogue Scale every 4 hours for 48 hours (0=no pain 10=most sever pain)
Secondary outcomes:
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt
Study officials:
References:
Clinical trial NCT04377165: Innovative Tool to Limit Spread of COVID 19 in Residential Aged Care Facilities
Official title: Innovative Tool to Limit Spread of COVID 19 in Residential Aged Care
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: COVID
Influenza
Gastroenteritis
Keywords: Infection Control
Lead sponsor: The University of Queensland
Sponsor class: OTHER
First posted: 2020-05-06
Enrollment: 34
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SEQUENTIAL
Primary purpose: PREVENTION

Brief summary: This project is a randomised trial in order to determine if "gamification" can result in behaviour change for healthcare workers in the residential aged care setting. The app is for Age Care and care workers at the front line who are working to protect those most vulnerable to COVID-19. There are 2 groups in this trial on group will receive current and accurate information from an app. The other group will receives the app with the addition of a gamification competent, this will include rewarding experiences for staff doing safety behaviours and wellbeing behaviours. The purpose of the gamification is to create a calming and reassuring experience that injects positivity and joy where possible during this stressful time.

Detailed description: The study design will be a multi- centre cluster randomised control trial, where Age Care facilities are randomised into two groups:

1. Newsfeed- gets the app with newsfeed only
2. Gamification group- gets the full gamified app, including the newsfeed Workers in our network of residential aged care facilities will be invited to participate in a study of communication of information regarding COVID-19 and how they will play a role in preventing its spread.

Eligibility criteria: Inclusion Criteria:

* Age Health Care Worker

Exclusion Criteria:

-

Primary outcomes:
measure: To compare the hours of sick leave used over the course of the 4-week period post randomisation for each group
timeFrame: 4 weeks
Secondary outcomes:
measure: To compare handwashing behaviour
timeFrame: 4 weeks
measure: To compare self-testing rates
timeFrame: 4 weeks
measure: To compare the level of surface wipe down
timeFrame: 4 weeks
measure: To compare number of COVID-19 tests completed in Facilities
timeFrame: 4 weeks
measure: To compare the number of COVID 19 infections in facilities
timeFrame: 4 weeks
measure: To compare the other types of outbreaks (Flu, gastroenteritis)
timeFrame: 4 weeks
measure: To compare the awareness of COVID 19 training available to workers in the facilities
timeFrame: 4 weeks
measure: To compare the awareness of PPE training available to workers in the facilities
timeFrame: 4 weeks
measure: To compare the levels of PPE material used in
timeFrame: 4 weeks
measure: To compare the wellbeing and self-efficacy of the two groups
timeFrame: 4 weeks
Other outcomes:
Locations:
Study officials:
affiliation: The University of Queensland
name: David L Paterson, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00564265: Current Management of Gastrointestinal Stromal Tumors (GIST) in the Region of Coquimbo
Official title: Outcomes of Surgical Treatment of Gastrointestinal Stromal Tumors in the IV Region of Chile
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Gastrointestinal Stromal Tumors
Keywords: GIST
Lead sponsor: Cirujanos la Serena
Sponsor class: OTHER
First posted: 2007-11-27
Enrollment: 24
Sex: ALL
Minimum age (years): 15
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients operated on for GIST

Brief summary: This is a retrospective analysis and description of the preferred diagnostic and treatment methods employed on GIST on the Region of Coquimbo from 2003 to 2008.


Eligibility criteria: Inclusion Criteria:

* All operated patients with GIST
* Positive immunohistochemistry

Exclusion Criteria:

* Patients with GIST not operated
* Patients with GIST operated on but without immunohistochemistry

Primary outcomes:
measure: Number of Patients Who Survived
timeFrame: 5 years
Secondary outcomes:
Other outcomes:
Locations:
city: La Serena
country: Chile
facility: Hospital De La Serena
state: Coquimbo
Study officials:
affiliation: Hospital de La Serena
name: Marcelo A Beltran, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03079765: Training Educators to Conduct Functional Behavior Assessment Via Telehealth
Official title: Training Educators to Implement Behavioral Assessment and Treatment Procedures in School Settings Via Telehealth
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Autism Spectrum Disorder
Keywords: Telehealth
Functional behavior assessment
Lead sponsor: University of Colorado, Denver
Sponsor class: OTHER
First posted: 2017-03-14
Enrollment: 12
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: SEQUENTIAL
Primary purpose: TREATMENT

Brief summary: This study evaluates the effects of delivering training services via telehealth to educators in rural schools. The investigators hope to increase the accuracy with which educators implement functional behavior assessments in schools. During the study, participants will receive training on functional behavior assessments at different periods. When one school is receiving training, other schools will not be receiving training. The purpose will be to show increased accuracy of functional behavior assessments only occur following training.

Detailed description: Training services for educators typically occurs in-vivo with experts providing immediate feedback and modeling to shape behavior. These types of training experiences may not be accessible for all educators though. The current study will evaluate delivering behavioral skills training (e.g., feedback and error correction) via telehealth for educators conducting functional behavior assessments. The components of the functional behavior assessment that will be targeted are open-ended interviews, stimulus preference assessments, direct observations of problem behavior, and a functional communication training program. With at least three different schools, the investigators will introduce training delivered via telehealth one at a time to show that increases in acquisition of the various components of the functional behavior assessment only occur following telehealth-based training.

Eligibility criteria: Inclusion Criteria:

* Must be an educator who conducts functional behavior assessment.
* Must be training to become a registered behavior technician.

Exclusion Criteria:

Primary outcomes:
measure: Increased functional behavior assessment procedural fidelity
timeFrame: 1 hour
Secondary outcomes:
Other outcomes:
Locations:
city: Aurora
country: United States
facility: University of Colorado, Anschutz Medical Campus
state: Colorado
Study officials:
affiliation: University of Colorado, Denver
name: Patrick Romani, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02990065: Optimizing Protein Intake and Nitrogen Balance in Adult Critically Ill Patients
Official title: Optimizing Protein Intake and Nitrogen Balance in Adult Critically Ill Patients: a Randomized Controlled Trial (OPINiB STUDY)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Protein Deficiency
Keywords: PROTEIN SUPPLEMENTATION
NUTRITIONAL STATUS
Lead sponsor: University of Padova
Sponsor class: OTHER
First posted: 2016-12-12
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purposes of the study are:

* To strictly ensure the appropriate level of protein and caloric provision in critical illness, according to the latest literature recommendation;
* To determine if an association exists between protein intake and nitrogen balance in the context of a nutrition with appropriate protein provision based on the latest literature recommendations, rather than in a standard diet with a caloric target weight-based. Creatinine clearance will also be evaluated to determine if there is any harmful effect to the kidney secondary to an elevated BUN.
* To determine if there is a difference in ICU mortality rate between the current nutrition standard and a hyperproteic nutrition protocol.


Eligibility criteria: Inclusion criteria:

* Age \> 18 years
* Receiving PN and/or EN nutrition
* Indwelling urinary catheter
* Mechanically ventilated patients

Exclusion criteria:

* Age \< 18 years
* Chronic renal or hepatic failure
* Current or history (past 6 months) of GI bleeding
* BMI \>30 kg/m2 o \<18 kg/m2
* Terminally ill patients
* Pregnancy

Primary outcomes:
measure: nitrogen balance (gr)
timeFrame: change from baseline through study completion, an average of 15 days
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Danielis M, Lorenzoni G, Cavaliere L, Ruffolo M, Peressoni L, De Monte A, Muzzi R, Beltrame F, Gregori D. Optimizing Protein Intake and Nitrogen Balance (OPINiB) in Adult Critically Ill Patients: A Study Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2017 May 9;6(5):e78. doi: 10.2196/resprot.7100.
Clinical trial NCT01688765: Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis
Official title: Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Psychotic Disorders
Keywords: Schizophrenia
Schizoaffective disorder
Bipolar disorder
Lead sponsor: Mclean Hospital
Sponsor class: OTHER
First posted: 2012-09-20
Enrollment: 187
Sex: ALL
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: First episode psychosis patients Healthy controls

Brief summary: The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.

Detailed description: The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.

The study design is case-control, there are no interventions.

Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of first episode of a psychotic disorder
* Healthy controls with no psychiatric disorder history

Exclusion Criteria:

* Significant neurological or medical illness history
* Ages \<18 or \>45

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Belmont
country: United States
facility: McLean Hospital
state: Massachusetts
Study officials:
affiliation: Mclean Hospital
name: Dost Ongur, MD PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02680665: Ameparomo Capsules 250 mg Drug Use Investigation
Official title: AMEPAROMO CAPSULES 250 MG DRUG USE INVESTIGATION
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Intestinal Amebiasis
Lead sponsor: Pfizer
Sponsor class: INDUSTRY
First posted: 2016-02-11
Enrollment: 120
Sex: ALL
Minimum age (years): 15
Maximum age (years): 99
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Sites of infection department, internal medicine, and other relevant departments.

Brief summary: This Study is intended to evaluate the safety and effectiveness of Ameparomo Capsules 250 mg under actual medical practice.


Eligibility criteria: Inclusion Criteria:

* Patients with no history of using this product

Exclusion Criteria:

* No exclusion criteria are set out in this study.

Primary outcomes:
measure: Number of Participants With Adverse Drug Reactions
timeFrame: 38 days at maximum
Secondary outcomes:
measure: Proportion of Cyst Negative
timeFrame: 10 days + 3 months at maximum
measure: Overall Clinical Response Rate
timeFrame: 10 days at maximum
Other outcomes:
Locations:
Study officials:
affiliation: Pfizer
name: Pfizer CT.gov Call Center
role: STUDY_DIRECTOR
References: