Clinical trial NCT02528630: Progressive Strength in Hand Osteoarthritis
Official title: Effectiveness of a Progressive Resistance Strength Program on Hand Osteoarthritis: a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Hand Osteoarthritis
Lead sponsor: Federal University of São Paulo
Sponsor class: OTHER
First posted: 2015-08-19
Enrollment: 60
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients.

Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients.

Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.


Eligibility criteria: Inclusion Criteria:

* diagnostic of hand OA according to american college of rheumatology of at least 1year;
* age over 50 years;
* both genders;
* pain in interphalangeal joints between 3-8 cm on a 10-cm numerical pain scale

Exclusion Criteria:

* other joint disease in hands;
* other rheumatic systemic disease;
* surgery in hands or writs;
* exercise or joint injection in hands in the previous 3 months;
* disability to perform the exercises.

Primary outcomes:
measure: Change in Pain
timeFrame: Baseline, after 6 and 12 weeks
Secondary outcomes:
measure: Change in hand function
timeFrame: Baseline, after 6 and 12 weeks
measure: Change in Patient satisfaction with treatment
timeFrame: 6 and 12 weeks
measure: Change in grip strength
timeFrame: Baseline, after 6 and 12 weeks
measure: Change in hand function
timeFrame: Baseline, after 6 and 12 weeks
measure: Change in pinch stength
timeFrame: Baseline, after 6 and 12 weeks
Other outcomes:
Locations:
city: Sao Paulo
country: Brazil
facility: Universidade Federal de Sao Paulo
state: SP
Study officials:
References: