Clinical trial NCT06552013: Action Towards Health Equity and Improved Air Quality in the Duwamish Valley: A Multilevel Asthma Intervention
Official title: Action Towards Health Equity and Improved Air Quality in the Duwamish Valley: A Multilevel Asthma Intervention
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Asthma in Children
Keywords: air quality
Lead sponsor: University of Washington
Sponsor class: OTHER
Collaborators: name: National Institute of Environmental Health Sciences (NIEHS)
First posted: 2024-08-13
Enrollment: 80
Sex: ALL
Minimum age (years): 6
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The goal of this randomized control trial is to learn if box fans and filters can reduce asthma symptoms and improve indoor air quality in children ages 6 - 17 years old with asthma living in the Duwamish Valley, Seattle, Washington. The main question it aims to answer are:

* Do box fans with filters improve asthma symptoms?
* Do box fans with filters improve an objective measure used to monitor lung function known as forced expiratory volume during the first second (FEV1)? Researchers will compare children living in households with high quality filters to those in households with sham filters to see if air quality and asthma symptoms improve.

Participants will

* fill out several questionnaires
* monitor their lung function with a peak flow meter
* place an air monitor in their homes to monitor indoor air quality
* run the box fan when they are at home


Eligibility criteria: Inclusion Criteria:

* age (6-17 years)
* poorly controlled physician diagnosed asthma defined as more than four days with asthma symptoms in the past two weeks, use of asthma rescue medication for more than four days in the past two weeks, or health care utilization due to asthma in the past year (hospitalization, emergency room visit, or unscheduled clinic visit)
* living in Georgetown and South Park neighborhoods of Seattle

Exclusion Criteria:

* children with unstable housing or shared custody arrangements

Primary outcomes:
measure: Asthma symptoms
timeFrame: ACQ will be measured weekly for 6 consecutive weeks, two pre-intervention weeks (before box fans have been given to participant) and four weeks while fans are being used in the home. Symptoms will also be assessed at the six month follow-up visit.
measure: FEV1
timeFrame: FEV1 measures will be taken daily, once in the morning and once at night for the six week study time frame. Prior to the six month follow up we will ask participants to take three consecutive days of FEV1 measurements, for an additional 6 measures
Secondary outcomes:
measure: Asthma quality of life
timeFrame: Will be evaluated at baseline (visit 1), after 6 weeks (visit 3) and at 6 month follow up (visit 4)
measure: Use of rescue medications
timeFrame: ACQ will be measured weekly for 6 consecutive weeks, two pre-intervention weeks (before box fans have been given to participant) and four weeks while fans are being used in the home. Symptoms will also be assessed at the six month follow-up visit.
measure: Health care utilization in the past month
timeFrame: Will be evaluated at baseline (visit 1), after 6 weeks (visit 3) and at 6 month follow up (visit 4)
Other outcomes:
Locations:
city: Seattle
country: United States
facility: Duwamish River Community Coaltion
state: Washington
Study officials:
affiliation: University of Washington
name: Anjum Hajat, PhD, MPH
role: PRINCIPAL_INVESTIGATOR
References: