Clinical trial NCT04154566: Influence of Aerobic Exercise on Inhibitory Control of Excutive Function in Spastic Hemiplegic C.P
Official title: Influence of Aerobic Exercise on Inhibitory Control of Excutive Function in Spastic Hemiplegic Cerebral Palsy: A Randomized Controlled Trail
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Spastic Hemiplegic Cerebral Palsy
Keywords: Hemiplegic cerebral palsy
inhibitory control of executive functions.
aerobic exercise.
Lead sponsor: South Valley University
Sponsor class: OTHER
First posted: 2019-11-06
Enrollment: 60
Sex: ALL
Minimum age (years): 7
Maximum age (years): 11
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: They were assigned randomly into two equal groups. Group (A) the study group received aerobic exercise in addition to selected physical therapy program. And group (B) the control group received the same selected physical therapy program only. The treatment was conducted for one hour, three times / weak for three successful months.
Primary purpose: TREATMENT

Brief summary: The study was conducted to assess the influence of aerobic exercise on inhibitory control of executive functions in spastic hemiplegic cerebral palsy.

Detailed description: Inhibitory control of executive functions (EF) is one of the main specific cognitive impairments that affect children with cerebral palsy, cognitive skills begin to develop in infancy and continuing through the pre-school years, childhood and into adolescence it changes across the lifespan of an individual and has great effect on their participation and quality of life. The aim of study was to assess the influence of aerobic exercise on inhibitory control of executive functions in spastic hemiplegic cerebral palsy. Sixty children with spastic hemiplegic cerebral palsy were enrolled in this study and were assessed for eligibility. Their aged ranged from seven and eleven years. They were assigned randomly into two equal groups. Group (A) the study group received aerobic exercise in addition to selected physical therapy program. And group (B) the control group received the same selected physical therapy program only. The treatment was conducted for one hour, three times / weak for three successful months. Eriksen flanker test and Stroop Color-Word test were used to assess inhibitory control of EF pre and post treatment.

Eligibility criteria: Inclusion Criteria:

* Their aged ranged from seven and eleven years.
* they were from both sexes.
* they have left side hemiplegic cerebral palsy.
* they were able to walk independently.

Exclusion Criteria:

* children with visual or auditory problems.
* children with history of drug intake that may affect the cognitive function.
* medically unstable children especially with cardiovascular disorders.
* uncooperative children.

Primary outcomes:
measure: The mean values of the Flanker test accuracy, congrunent reaction time and incongruent reaction time
timeFrame: Eriksen flanker test was assessed at day 0, 90.
measure: The mean values of the Stroop test accuracy, congrunent reaction time and incongruent reaction time
timeFrame: Stroop Color-Word test was assessed at day 0, 90.
Secondary outcomes:
Other outcomes:
Locations:
city: Qina
country: Egypt
facility: South Valley University, Faculty of Physical Therapy
Study officials:
affiliation: South Valley University, Faculty of Physical Therapy
name: Nehad A. Abo-zaid, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: South Valley University, Faculty of Physical Therapy
name: Mohammed E. Ali, PhD student
role: PRINCIPAL_INVESTIGATOR
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