Clinical trial NCT05564065: Comparison of Intra-articular Steroid Injection and Radiofrequency Thermocoagulation in Coxarthrosis Patients
Official title: Comparison of Intra-articular Steroid Injection and Radiofrequency Thermocoagulation of the Sensory Branches of the Femoral and Obdurator Nerves in Coxarthrosis Patients
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Pain Hip Burning
Lead sponsor: Istanbul University
Sponsor class: OTHER
First posted: 2022-10-03
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Two groups: 1. intraarticular steroid injection of hip joint; 2. Radiofrequency thermocoagulation of femoral and obturator nerve terminal sensory branches of hip joint
Primary purpose: SUPPORTIVE_CARE

Brief summary: The investigators aimed that the Comparison of effectiveness of the intra-articular steroid injection and radiofrequency thermocoagulation of the sensory branches of the femoral and obdurator nerves in coxarthrosis patients

Detailed description: Osteoarthirtis is a deficency of articular cartilge which is caused by genetic, metabolic and biochemical factors. This is a pathologic period with cartilage, bone and sinovium destruction.

Pharmacological treatments and/or phsiycal medicine may not be enough to reduce pain in patients with chronic pain of osteoarthiritis. Intraarticular steroid injection is the most common used intervention method in analgesia of hip osteoarthirtis. Thus; cartilage inflammation can be decelerated and osteophyte formation can be prevented. On the other hand; because of less vascularity of hip joint, frequent steroid injections may cause aseptic necrosis.

In past decades, treatment to pain of hip joint pain caused by ostheoarthrits, radiofrequency ablation treatment is used to sensory nerves which cause pain. Especially, it can be a solution in patients who do not want to undergo a surgery.

Patients diagnosed with coxarthrosis will be randomly divided into two groups. One group will receive intra-articular steroid injection and the other group will receive radiofrequency thermocoagulation to the hip sensory nerve branches (femoral and obdurator). It was planned to compare the vas scores of the patients before and 1-3 months after the procedure with their effectiveness.

Eligibility criteria: Inclusion Criteria:

* - Older than 18-year-old
* Clincal, radiological (Grade 3-4) and laboratory examinations ara related with diagnosis of hip joint osteoarthirtis
* Despite of previous medical and physical treatment, VAS score \> 5 and above
* Norological examination without critical motor and sensory deficency
* Patients who sign informed consent.

Exclusion Criteria:

* Coagulation disorders (bleeding diathesis)
* Usage of antitrombotic, anticoagulant medications
* Sepsis and local infection on intervention area
* Allergic to any of drugs which is used in intervention
* Without informed consent approval

Primary outcomes:
measure: Visual Analog Scale comparison
timeFrame: Baseline
measure: Visual Analog Scale comparison
timeFrame: 1.month
measure: Visual Analog Scale comparison
timeFrame: 3.month
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Halil Cetingok
state: Fatih
Study officials:
affiliation: Istanbul University
name: Halil Cetingok, Ass. Prof
role: STUDY_DIRECTOR
References: