Clinical trial NCT04800900: Effectiveness of Pharmaceutical Interventions in Hospitalized Patients
Official title: Effectiveness of Pharmaceutical Interventions in the Omission of Prescription and Desprescription of Medications in Hospitalized Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Safety Issues
Lead sponsor: Federal University of Bahia
Sponsor class: OTHER
First posted: 2021-03-16
Enrollment: 332
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: The presence of multimorbidities is very common among the elderly, which become major consumers of medicines. The process of prescribing medicines for the elderly should be done with caution, as the use of some medications may present more risks than benefits in this range age. Potentially inappropriate prescribing for the elderly has become a global concern for the promotion of an adequate pharmacotherapy, it becomes essential to be aware of the effectiveness and safety of medicines and the knowledge of which drugs whose risks of serious adverse reactions outweigh the benefit of your referral. In this sense, the present study has aim to evaluate the effectiveness of pharmaceutical interventions in frequency of omission of drugs with proven efficacy for cardiovascular diseases and promotion of treatment prescription inappropriate and polypharmacy. A prospective quasi experimental before and after study will be carried out in elderly patients diagnosed with cardiovascular disease admitted to the Ana Nery hospital, Salvador, Bahia, Brazil. A convenience sample will be collected, the data will be released and revised in a database built in the SPSS software and analyzed in the program statistic R and SPSS. At the end of the study, it is expected a decrease in the frequency of omission of medications and promotion of prescription drugs inappropriate.


Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of cardiovascular disease
* Discharge after 24 hours

Exclusion Criteria:

\* Death

Primary outcomes:
measure: Effectiveness of pharmaceutical interventions measured by proportion of accepted interventions and all interventions
timeFrame: The acceptance of all pharmaceutical interventions related to inappropriate prescribed drugs and omission of prescription during the hospitalization of the patient will be evaluated, through study completion, an average of 1 year
Secondary outcomes:
measure: Incidence of polypharmacy in elderly people with cardiovascular diseases measured by prescription containing five or more drugs
timeFrame: First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year
measure: Incidence of omission of prescription drugs with proven efficacy for cardiovascular diseases measured by the START criteria
timeFrame: First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year
measure: Incidence of potentially inappropriate drug prescription in elderly people with cardiovascular diseases measured by the Beers criteria
timeFrame: First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year
Other outcomes:
Locations:
city: Salvador
country: Brazil
facility: Hospital Ana Nery
state: Bahia
Study officials:
References: