louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT05604430: Pre-hospital Ventilation Clinical Study
Official title: Pre-hospital Ventilation Clinical Study
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Altered Mental Status
Sepsis
Heart Failure
Hemorrhage
Respiratory Distress Syndrome, Adult
Cardiac Arrest
Keywords: Ventilation
Pre-Hospital
Lead sponsor: Zoll Medical Corporation
Sponsor class: INDUSTRY
First posted: 2022-11-03
Enrollment: 500
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Cases where participating EMS Agencies use ZOLL 731 Series ventilator in accordance with device labeling and Agency protocols in a pre-hospital setting

Brief summary: This study will collect and characterize ventilator use during patient care with a ZOLL 731 Series ventilator in a pre-hospital setting.

Detailed description: This is a prospective, observational study.

ZOLL will develop a methodology to collect and transfer ventilator data from the device to ZOLL to allow for a characterization of ventilator use in the pre-hospital setting. This knowledge and experience will subsequently be used to inform development of a mechanism to allow for automatic data collection and transmission from ZOLL ventilators to a central data repository. These data will be used to provide feedback, reporting, and benchmarking to individual agencies and departments on their ventilator use as well as aggregate use data from all ventilators to allow for comparisons.

Enrollment in this study is expected to take approximately 24 months. No patient outcome data will be collected.Participants are enrolled once data have been downloaded from the ventilator via RescueNet® VentReview software. Participants will not be followed after the assessment of study objectives.

Eligibility criteria: Inclusion Criteria:

* Candidates for this study must meet all of the following Inclusion criteria:

  1. Ventilated using ZOLL 731 Series ventilator with Release 5 (or greater) software
  2. Data recorded in ventilator data file

Exclusion Criteria:

* None

Primary outcomes:
measure: Ventilator modes used
timeFrame: Through study completion, an average 1 hour
measure: Ventilator settings used
timeFrame: Through study completion, an average 1 hour
measure: Ventilator Alarm type
timeFrame: Through study completion, an average 1 hour
measure: Ventilator Alarm Frequency
timeFrame: Through study completion, an average 1 hour
Secondary outcomes:
Other outcomes:
Locations:
city: Baton Rouge
country: United States
facility: East Baton Rouge EMS
state: Louisiana
Study officials:
affiliation: East Baton Rouge EMS
name: Dan Godbee, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05288530: Satisfaction, Pain and Function Outcomes of Breast Reduction Patients
Official title: Satisfaction, Pain and Function Outcomes of Breast Reduction Patients: A Retrospective Chart Review and Patient Follow up
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Macromastia
Hypertrophy Breast
Lead sponsor: Claytor Noone Plastic Surgery
Sponsor class: OTHER
First posted: 2022-03-21
Enrollment: 35
Sex: FEMALE
Minimum age (years): 21
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Females age 21-70 with a diagnosis of hypertrophy of the breast who underwent surgical intervention

Brief summary: To explore the indications and benefits of breast reduction. The investigators suspect all of the patients in this population suffer from neck/back pain and limitations in function. The investigators also want to review the patients in this group to determine if the amount of breast tissue removed or previous breast size affects outcomes for these patients. Patients will then be contacted for outcome data and satisfaction information. Ultimately, this information may lead to improvements in management and education of patients with macromastia.


Eligibility criteria: Inclusion Criteria:

* Females
* Ages 21-71 years-old
* Hypertropy of the breast
* Macromastia
* post-surgical intervention for macromastia or hypertrophy of the breast

Exclusion Criteria:

* Males
* BMI\>40
* Hypertrophy of the breast but without surgical intervention
* Macromastia but without surgical intervention

Primary outcomes:
measure: DASH questionnaire
timeFrame: 6 months
measure: Breast Q questionnaire
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Claytor Noone Plastic Surgery
name: Brannon Claytor
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02438930: Client-Centered Counseling During Routine/Opt-Out HIV-Testing in Uganda
Official title: Client-Centered Counseling During Routine/Opt-Out HIV-Testing in Uganda
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: HIV
Sexual Behavior
Lead sponsor: UConn Health
Sponsor class: OTHER
Collaborators: name: Makerere University
name: National Institute of Mental Health (NIMH)
name: Rhode Island Hospital
First posted: 2015-05-08
Enrollment: 333
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This study pilot tests and intervention to help individuals reduce their risk for acquiring or transmitting HIV. The intervention is implemented when people are tested for HIV in an outpatient clinic in rural Uganda. Approximately half of participants will receive the intervention and the other half will receive the usual counseling provided during HIV counseling and testing.


Eligibility criteria: Inclusion Criteria:

1. at least 18 years of age,
2. have come to the outpatient clinic for a medical concern (e.g., cough, malaria, but not those seeking voluntary HIV-counseling and testing,
3. sexually active within the prior 3-months,
4. not currently pregnant,
5. no confirmed HIV-positive test result prior to the present HIV-test, and
6. live not more than 30km from Gombe Hospital in Uganda (to facilitate follow-up)

Exclusion Criteria:

* less than 18 years of age,
* having come to the clinic seeking voluntary HIV-counseling and testing,
* not sexually active in prior 3 months,
* currently pregnant,
* confirmed prior HIV positive test,
* live more than 30km from the hospital

Primary outcomes:
measure: Sexual risk behavior
timeFrame: 6 months
Secondary outcomes:
measure: Uptake of partner testing
timeFrame: 6 months
Other outcomes:
Locations:
city: Gombe
country: Uganda
facility: Gombe Hospital
Study officials:
affiliation: UConn Health
name: Susan M Kiene, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Kiene SM, Sileo K, Wanyenze RK, Lule H, Bateganya MH, Jasperse J, Nantaba H, Jayaratne K. Barriers to and acceptability of provider-initiated HIV testing and counselling and adopting HIV-prevention behaviours in rural Uganda: a qualitative study. J Health Psychol. 2015 Feb;20(2):173-87. doi: 10.1177/1359105313500685. Epub 2013 Sep 20.
Clinical trial NCT00780130: SPARQ and Core Proprioception
Official title: The Relationship of Core Stability to Core Proprioception
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Proprioception
Core Strength
Lead sponsor: Logan College of Chiropractic
Sponsor class: OTHER
First posted: 2008-10-27
Enrollment: 20
Sex: ALL
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Sampling method: NON_PROBABILITY_SAMPLE
Study population: asymptomatic normals

Brief summary: The purpose of this investigation is to determine the relationship of core stability to core proprioception

Detailed description: As no previous research has been reported correlating the SPARQtm method of athletic performance with the McGill Side Bridge test and core joint position error, this study is designed as a pilot. The subject's core stability will be measured with the SPARQtm method of athletic performance and the McGill Side Bridge test for core stability. Core proprioception will be determined using the standard test for proprioception, Joint Position Error (JPE) testing, with the Skill Technologies motion capture device. All participants will receive the SPARQtm method of athletic performance testing, the McGill Side Bridge test for core stability and the core joint position error tests twice, one week apart.

Eligibility criteria: Inclusion Criteria:

* college student, staff, or faculty members;
* History of thoracic / lumbar injuries for inclusion into the injured group.
* No history of thoracic / lumbar injuries for inclusion into the normal group.
* Ages 20 to 50
* History of previous athletic performance.

Exclusion Criteria:

* Previous lower extremity injury, surgery, visual or vestibular condition affecting balance
* Current acute illness that have an adverse effect on balance or core strength
* Local infection, injury or other malignancy
* Any unstable joints of the lower extremity or spine
* Any Spinal manipulation within 48 hours
* Prescription medication or supplement that affects blood pressure
* Pregnancy
* Diagnosis of severe hypertension (200-161/120-100 mmHg)
* Incapable of exercise for 15 minutes without hortness of breath
* Heart failure, kidney diseases and mental disorders

Primary outcomes:
measure: Mcgill sidebridge test proprioception testing SPARQ testing
timeFrame: Two testing sessions one week apart.
Secondary outcomes:
Other outcomes:
Locations:
city: Chesterfield
country: United States
facility: Logan College of Chiropractic
state: Missouri
Study officials:
References:
Clinical trial NCT04162730: Validity, Reliability and Responsiveness of Pain Sensitization Questionnaire
Official title: Validity, Reliability and Responsiveness of Pain Sensitization Questionnaire
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Pain Syndrome
Pain, Chronic
Knee Osteoarthritis
Lead sponsor: Acibadem University
Sponsor class: OTHER
First posted: 2019-11-14
Enrollment: 150
Sex: ALL
Minimum age (years): 40
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Knee osteoarthritis patients who have chronic pain

Brief summary: The aim of this study was to translate the Pain Sensitivity Questionnaire, which was developed to determine the level of pain sensitivity of individuals, to Turkish and to evaluate the validity and reliability of the Turkish version of the scale on knee osteoarthritis patients, and as well as to perform cultural adaptation. Pain sensitivity assessment is used to predict treatment or surgical outcomes of individuals. IPain Sensitivity Questionnaire is a frequently used scale that correlates with experimental pain tests and is used in studies conducted in different patient groups. We believe that adding this scale to our language will contribute to other studies in this field.


Eligibility criteria: Inclusion Criteria:

* Not having oral or written communication problems in Turkish,
* Diagnosis of knee osteoarthritis after clinical examination and radiological imaging,
* Being 40 years or older,
* To have neurological competence and cognitive level to answer scale questions.

Exclusion Criteria:

* To have fibromyalgia syndrome or neurological disease that may affect pain sensitivity levels of individuals,
* To have undergone surgery involving the knee in the last 1 year,
* The presence of peripheral neuropathy and neuropathy is therefore to be taking medication.

Primary outcomes:
measure: Pain Sensitivity Questionnaire
timeFrame: 1-4 week
Secondary outcomes:
measure: Pain Catastrophization Scale
timeFrame: 1-4 week
measure: Pressure Pain Threshold
timeFrame: One day
Other outcomes:
Locations:
city: İ̇stanbul
country: Turkey
facility: Özgül Öztürk
Study officials:
References:
Clinical trial NCT06046430: Investigation of Laterality and Sensory Acuity Abilities of Frozen Shoulder Patients
Official title: Investigation of Laterality and Sensory Acuity Abilities of Frozen Shoulder Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Frozen Shoulder
Laterality Defects
Lead sponsor: Harran University
Sponsor class: OTHER
First posted: 2023-09-21
Enrollment: 49
Sex: ALL
Minimum age (years): 35
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The sample of the study will consist of patients who applied to Harran University Hospital and were diagnosed with frozen shoulder.

Brief summary: The brain contains the body representation necessary for normal functioning, including goal-directed movements and behaviors. Body representation involves integrated sensory input and ideas about one's body. Both executed and imagined movements depend on the representation of the body in the cortical area. Laterilization is one of the motor imagery methods that requires activation of proprioceptive, somatosensory and premotor regions and enables the determination of pain-induced cortical changes. Another method to determine pain-related somatosensory changes is the two-point discrimination test.

It is suggested that laterization and sensory acuity responses may change due to long-term pain and stiffness experienced in people with frozen shoulders. Therefore, the aim of this study is to investigate the laterization and sensory acuity abilities of patients with frozen shoulder.


Eligibility criteria: Frozen Shoulder Group:

Inclusion Criteria:

Patients with shoulder pain of at least six months' duration secondary to tendinopathy and/or partial rotator cuff tear; Patients with ability to follow simple orders; iii) Patients with ability to sign to provide informed consent

Exclusion Criteria:

Normal passive ROM External ROM \< 30 To have received treatment (physiotherapy, intra-articular injection, surgery) related to the existing complaint Pain \< 3 according to the numbered pain assessment scale

Healthy group :

Inclusion criteria:

No actual shoulder pain or previous history of shoulder complaints including Frozen Shoulder.

Primary outcomes:
measure: Right-Left Discrimination
timeFrame: Baseline
measure: Acuity
timeFrame: Baseline
Secondary outcomes:
measure: Pain Intensity
timeFrame: Baseline
measure: Active Range of Motion (AROM) Assessment
timeFrame: Baseline
measure: Central sensitization
timeFrame: Baseline
measure: Pain Catastrophizing
timeFrame: Baseline
measure: Anxiety and Depression
timeFrame: Baseline
Other outcomes:
Locations:
city: Şanlıurfa
country: Turkey
facility: Harran University
Study officials:
References:
Clinical trial NCT02695030: Low-profile Visualized Intraluminal Support -HUD
Official title: MicroVention Low-profile Visualized Intraluminal Support (LVIS*) or LVIS Jr Humanitarian Use Device (LVIS HUD)
Study type: EXPANDED_ACCESS
Overall status: APPROVED_FOR_MARKETING
Conditions: Giant Wide Necked Aneurysms
Lead sponsor: NYU Langone Health
Sponsor class: OTHER
First posted: 2016-03-01
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT

Brief summary: The MicroVention Low-profile Visualized Intraluminal Support (LVIS\*) Device is intended for use with bare platinum embolic coils for the treatment of unruptured, wide neck (neck greater than or equal to 4 or a dome to neck ratio less than two), intracranial, saccular aneurysms arising from a parent vessel with a diameter of greater than or equal to 2.5mm and less than or equal to 4.5mm.

Detailed description: Wide neck aneurysms are very difficult to treat both surgically and endovascularly with clipping or coiling. The availability of this neurovascular flow diverter as a Humanitarian Use Device has provided an additional approach to aneurysm occlusion using endovascular techniques.

Eligibility criteria: Inclusion Criteria:

* Wide neck (neck greater than or equal to 4 or a dome to neck ratio less than two),Intracranial, saccular aneurysm arising from a parent vessel with a diameter of greater than or equal to 2.5mm and less than or equal to 4.5mm.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: New York
country: United States
facility: New York University School of Medicine
state: New York
Study officials:
affiliation: New York University Medical School
name: Howard Riina, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02151630: Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar Warts
Official title: Comparison of 70% Pyruvic Acid Solution and Duofilm Solution in Treatment of Plantar Wart
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE2
PHASE3
Conditions: Plantar Wart
Keywords: wart
verruca vulgaris
topical therapy
pyruvic acid
salicylic acid
Lead sponsor: Isfahan University of Medical Sciences
Sponsor class: OTHER
First posted: 2014-05-30
Enrollment: 60
Sex: ALL
Minimum age (years): 12
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Plantar warts can be bothersome and painful requiring treatment. The investigators will compare the efficacy of pyruvic acid and salicylic acid in treating multiple plantar warts. Patients with multiple plantar warts will be randomized to receive either pyruvic acid 70% or compound salicylic acid solution (salicylic acid 16.7%, lactic acid 16.7%, and collodion 100%) applying topically twice a day for 4 weeks. Patients will be visited every 2 weeks for one month after starting treatment and then every one month for up to 3 months. The number and size of warts will be evaluated.


Eligibility criteria: Inclusion Criteria:

* aged 12 years and above
* multiple warts (at least 2)

Exclusion Criteria:

* mosaic warts
* already under any treatment for warts
* pregnant or lactating women

Primary outcomes:
measure: Wart number
timeFrame: From before to 3 months after
measure: Wart size
timeFrame: From before to 3 months after
Secondary outcomes:
Other outcomes:
Locations:
city: Isfahan
country: Iran, Islamic Republic of
facility: Skin Diseases and Leishmaniasis Research Center
Study officials:
affiliation: Isfahan University of Medical Sciences
name: Fatima Assaf, M.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Kwok CS, Holland R, Gibbs S. Efficacy of topical treatments for cutaneous warts: a meta-analysis and pooled analysis of randomized controlled trials. Br J Dermatol. 2011 Aug;165(2):233-46. doi: 10.1111/j.1365-2133.2011.10218.x. Epub 2011 May 26.
Clinical trial NCT05331430: Effectiveness of Dry Needling and Stretching in People With Fibromyalgia.
Official title: Effectiveness of Dry Needling and Stretching on Joint Range and Myofascial Pain at the Cervical Level in People With Fibromyalgia.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dry Needling
Stretch
Fibromyalgia
Keywords: Dry needling
Stretch
Fibromyalgia
Physical Therapy
Lead sponsor: Universidad de Murcia
Sponsor class: OTHER
First posted: 2022-04-15
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized clinical trial
Primary purpose: TREATMENT

Brief summary: Effectiveness of dry needling and stretching on joint range and myofascial pain at the cervical level in people with fibromyalgia

Detailed description: A randomised clinical trial will be conducted in which there will be 3 groups. One control group and 2 experimental groups; one of them will undergo dry needling of the upper trapezius fibres and the other will undergo passive stretching of the upper trapezius fibres. Both groups will have the joint range of cervical lateral tilt, pain measurement by algometer and visual analogue scale (VAS) measured. All these measurements will be taken before and after treatment. The participants of the study will be people who have been diagnosed with fibromyalgia at least 6 months before the start of the study, who are members of the FIBROFAMUR association. Association of Fibromyalgia, Chronic Fatigue, Rheumatic and Musculoskeletal Diseases of Murcia. The data collected will be: socio-demographic data, age, sex, measurement of cervical joint range using a goniometer and measurement of pain using an algometer and visual analogue scale (VAS). As undesirable effects, in exceptional cases, the dry needling technique may produce residual discomfort in the puncture area that may last between 1 and 3 days.

Eligibility criteria: Inclusion Criteria:

* Have a diagnosis of fibromyalgia at least six months before the start of the study.
* Be of legal age.
* Report at least one episode of neck pain in the last six months.

Exclusion Criteria:

* Surgical interventions or scars at cervical level.
* Dizziness or vertigo.
* Dermatological problems.
* Severe psychiatric disorders.

Primary outcomes:
measure: Goniometer measurement
timeFrame: One month
measure: Measurement of pain with an algometer.
timeFrame: One month
measure: Visual analogue scale (VAS)
timeFrame: One month
Secondary outcomes:
Other outcomes:
Locations:
city: Murcia
country: Spain
facility: Universidad de Murcia
Study officials:
affiliation: Universidad de Murcia
name: Angel Martínez Carrasco, PhD
role: STUDY_DIRECTOR
affiliation: Universidad de Murcia
name: Jose Quereda Ruiz, Graduated
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01447030: Long Time Follow up After HJ Following Iatrogenic Bile Duct Injuries
Official title: Langtidsopfølgning Efter Kirurgisk Behandling af Iatrogene galdevejslæsioner opstået i Forbindelse Med Cholecystektomi
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Biliary Strictur After Hepatojejunostomy (HJ)
Morbidity and Mortality After and Around HJ
Keywords: Biliary strictur
Hepatojejunostomy
Iatrogenic major bile duct injury
Lead sponsor: Odense University Hospital
Sponsor class: OTHER
Collaborators: name: Aalborg University Hospital
name: Aarhus University Hospital
name: Herlev Hospital
name: Rigshospitalet, Denmark
First posted: 2011-10-05
Enrollment: 139
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All patients with iatrogenic bile duct injury (BDI) after cholecystectomy reconstructed with hepatojejunostomia. Collecting data from 5 Danish tertiary hepato-biliary centres from january 1995 to may 2009.

Brief summary: Introduction: Bile duct injury (BDI) after cholecystectomy remains a serious complication with major implications for patient outcome. For most major BDIs, the recommended method of repair is a hepaticojejunostomy (HJ). We conducted a retrospective review from 5 Danish hepatobiliary centres aiming to examine the perioperative and the long-term outcome after reconstructive HJ.


Eligibility criteria: Inclusion Criteria:

* All patients with iatrogenic Bile duct injury (BDI) after cholecystectomy reconstructed with hepatojejunostomy/choledochojejunostomy.

Exclusion Criteria:

* Patients with non-cholecystectomy-related BDI or with cholecystectomy-related BDI that had been definitively managed by other techniques.

Primary outcomes:
measure: Stricture of HJ
timeFrame: days to years
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References: