Clinical trial NCT06598748: Effect of Mechanical Interface Mobilization Technique on Pain and Functional Status in Carpal Tunnel Syndrome
Official title: Effect of Mechanical Interface Mobilization Technique on Pain and Functional Status in Carpal Tunnel Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Carpal Tunnel Syndrome
Keywords: CTS
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 30
Sex: ALL
Minimum age (years): 24
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Participants were randomly assigned to the experimental group or control group. Participants were not notified which group was assigned to
Primary purpose: TREATMENT

Brief summary: The aim of this study is to find out the influence of mechanical interface mobilization technique which consists of 5 different steps, in management of carpal tunnel syndrome and how this technique effects pain and functional status in individuals who has carpal tunnel syndrome.

Detailed description: The median nerve gets entrapped in the wrist, causing carpal tunnel syndrome (CTS), the most prevalent peripheral neuropathy in the upper limb. A number of clinical findings, such as sensory issues with the first three digits of the hand sensory distribution of the median nerve, a positive Phalen test, weakness and atrophy of the thenar muscle, and electrophysiological findings (prolonged motor and sensory distal latencies of the median nerve) are used to diagnose CTS . The most frequent occupational risk factors for CTS are repetitive wrist and finger motions or holding uncomfortable wrist positions for extended periods of time. Tenosynovitis of the finger flexors, a thicker transverse carpal ligament, a fracture or dislocation of the distal radius or lunate, rheumatoid arthritis, lipoma, diabetes, and hyperthyroidism are other non-occupational causes . A combination of techniques has been used in the studies of Seradge H. et al and Sucher Benjamin M. Et al which included mechanical interface and neuro-dynamics, but the isolated effects of each method is yet to be determined by further studies as their combined effects are more focused on in the current literature. And that leads to an unclear decision about, which group of manual therapy techniques has better effects on individuals suffering from CTS .

Eligibility criteria: Inclusion Criteria:

* Positive Phalen test and Tinel Test.
* Positive symptoms of CTS (Pain, numbness, or tingling in the first three and lateral half of the fourth finger.

Exclusion Criteria:

* No previous surgical treatments at the wrist joint, no fractures or open wounds at the wrist.
* Patients with thoracic outlet syndrome, and cervical radiculopathy.
* History of carpal tunnel release surgery.
* Steroid injection in the carpal tunnel.
* Pregnant females.
* Metabolic diseases such as diabetes, severe thyroid disorders and anemia.

Primary outcomes:
measure: Visual analogue scale (VAS)
timeFrame: 4 week (will be measured at the end of every week)]
measure: Symptom Severity Scale
timeFrame: 1st week(pre) and 4th week(post)]
measure: Hand functional status scale
timeFrame: 1st week(pre) and 4th week(post)]
Secondary outcomes:
Other outcomes:
Locations:
city: Khushāb
country: Pakistan
facility: Dhqh Campus 2 Khushab
state: Punjab
Study officials:
affiliation: Riphah International University
name: Ramsha Tariq, MsOMPT
role: PRINCIPAL_INVESTIGATOR
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