Clinical trial NCT05113875: Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital
Official title: Health System Dynamic & Resource Requirement in a South African COVID-19 Field
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Field Hospitals
COVID-19 Pandemic
Health Systems
Global Health
Health Resources
Low-Income Population
Lead sponsor: University of Cape Town
Sponsor class: OTHER
First posted: 2021-11-09
Enrollment: 596
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population is from an underserved community utilizing public health services. The population in based in Mitchells Plain, Cape Town South Africa.

Brief summary: The aim of this study is to describe the patient clinical profile, resource requirements, and health system dynamics in a field hospital during the second wave of the Coronavirus (COVID-19) pandemic, leading to the outbreak of viral severe acute respiratory syndrome (SARS-CoV-2 virus), in South Africa. By describing the field hospital in this unique setting, the investigators hope to provide an efficient guide to similar settings across low- and middle-income countries.

This was a retrospective, single-center study. A total of 596 patients with confirmed COVID-19 were admitted to Mitchells Plain Hospital of Hope (MPHOH), Cape Town, South Africa, between January 1st and February 28th, 2021. Patient clinical characteristics, outcome, and resource allocation was collected. Daily hospital dynamics, including admissions, discharges, deaths and oxygen use was analyzed and compared to the local and national COVID-19 incidence rates.

Detailed description: The aim of the study is to amplify what is known about field hospitals in resource-constrained setting, so as to guide meaningfully the future COVID-19 public health response. Understanding not only the patient profile, but clinical resource requirements, and health system dynamic in a South African field hospital during the second wave of the COVID-19 pandemic can help in preparation for a future infection surge. This will shed light on the extent and timing of excess demand for intermediate care facilities for COVID-19 during peak infection periods in this region. Furthermore, lessons learnt here can guide efforts in similar settings across low-and middle-income countries.

Data was collected on all patients admitted to MPHOH between January 1st and February 28th 2021 using notes from patient folders' and an electronic hospital records systems. Patient demographics, clinical profile, resource utilization; as well as the hospital dynamics were collected. COVID-19 incidence rates were collected from the National Institute for Infectious Diseases, South Africa

A descriptive data analysis was performed to report the number, mean, median, and range of all relevant values. Hospital level data were summarized into weekly intervals, described and compared to COVID-19 incidence rates. Statistical data analysis was performed using R Statistical Computing program and Microsoft Excel.

Eligibility criteria: Inclusion Criteria:

* All patients admitted to the Mitchells Plain Hospital of Hope COVID-19 field hospital between 1st January 2021 and 29th February 2021. Patients admitted to the hospital must have been: over 18years of age, diagnosed with COVID-19 via polymerase chain reaction (PCR) test, transferred from a referring facility.

Exclusion Criteria:

* No patients were excluded.

Primary outcomes:
measure: Patient Demographics
timeFrame: January 1st to February 29th 2021
measure: Patient Demographics
timeFrame: January 1st to February 29th 2021
measure: Patient Clinical Condition
timeFrame: January 1st to February 29th 2021
measure: Patient Clinical Condition
timeFrame: January 1st to February 29th 2021
measure: Patient Clinical Condition
timeFrame: January 1st to February 29th 2021
measure: Patient Clinical Condition
timeFrame: January 1st to February 29th 2021
measure: Patient Clinical Condition
timeFrame: January 1st to February 29th 2021
measure: Patient Clinical condition
timeFrame: January 1st to February 29th 2021
measure: Hospital Human Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Human Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Human Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Physical Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Physical Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Physical Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Physical Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Physical Resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Hospital Physical resources Utilized
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Health System Dynamics
timeFrame: January 1st to February 29th 2021
measure: Local Incidence rates of COVID-19 infections
timeFrame: December 1st 2020 to February 29th 2021
measure: Local Incidence rates of COVID-19 infections
timeFrame: December 1st 2020 to February 29th 2021
Secondary outcomes:
Other outcomes:
Locations:
city: Cape Town
country: South Africa
facility: Mitchells Plain Hospital of Hope Covid-19 Field Hospital, Lentegeur Hospital
state: Western Province
Study officials:
References: