Clinical trial NCT06918158: Mobilization With Movement Versus Joint-Specific Manipulation in De Quervain's Tenosynovitis
Official title: Comparative Study on the Effectiveness of Mobilization With Movement Versus Joint Specific Manipulation on Pain and Function in Patient With Dequervains Tenosynovitis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Tenosynovitis
Keywords: Tenosynovitis
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2025-04-09
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Intervention model description: RCT
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: A comparative study on the effectiveness of mobilization with movement (MWM) versus joint-specific manipulation (JSM) in patients with De Quervain's tenosynovitis typically aims to assess how each technique impacts pain relief and functional improvement. De Quervain's tenosynovitis is an inflammation of the tendons around the thumb and wrist, often causing pain, swelling, and difficulty in performing everyday tasks. The study would likely compare the two interventions by measuring pain levels, range of motion, and overall functional outcomes before and after treatment. MWM involves applying specific, controlled movements while the patient is actively engaging in their joint motion, targeting the tissue's mobility and reducing pain. JSM, on the other hand, focuses on manipulating the joint directly to restore normal function, specifically targeting the wrist and thumb regions affected by the condition.

Detailed description: A comparative study on the effectiveness of Mobilization with Movement (MWM) versus Joint-Specific Manipulation (JSM) in patients with De Quervain's Tenosynovitis would delve deeper into the physiological mechanisms and clinical outcomes associated with each technique, providing valuable evidence for therapeutic decision-making. De Quervain's Tenosynovitis is a condition characterized by the inflammation of the tendons at the base of the thumb, particularly affecting the abductor pollicis longus and extensor pollicis brevis tendons. This condition is commonly caused by repetitive strain, overuse, or trauma, leading to pain, swelling, and restricted movement, which significantly impacts the patient's daily activities.

Eligibility criteria: Inclusion Criteria:o Patients clinically diagnosed with De Quervain's tenosynovitis

* Age between 25-45 years.
* Positive Finkelstein test.
* Pain over the first dorsal compartment.
* Limited wrist and thumb function.
* Willingness to take part and adhere to the study's guidelines.

Exclusion Criteria:Participants fall in this category would be excluded of the study.

* Previous surgery of wrist or thumb.
* Presence of neurological symptoms like numbness, weakeness.
* Rheumatological conditions like rheumatoid arthritis.
* Pregnancy.
* Presence of wrist fracture or osteoporosis.
* Carpel tunnel syndrome.

Primary outcomes:
measure: Pain Reduction - Measured using the Numeric Pain Rating Scale (NPRS) (0-10 scale).
timeFrame: 6 Months
Secondary outcomes:
measure: Wrist Function - Assessed with the Patient-Rated Wrist Evaluation (PRWE) (0-100 scale).
timeFrame: 6months
Other outcomes:
measure: Clinical Signs - Evaluated using Finkelstein's Test (Positive/Negative).
timeFrame: 6 months
Locations:
city: Malakand
country: Pakistan
facility: Riphah international University Malakand Campus
state: KPK
Study officials:
affiliation: Riphah International University
name: Dr.Nadeem Ahmad, MS
role: PRINCIPAL_INVESTIGATOR
References: