Clinical trial NCT03472300: Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals
Official title: Prevalence of Self-disclosed Knee Trouble and Use of Treatments Among Elderly Individuals from Frederiksberg Municipality - a Prospective Cohort Study
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Knee Osteoarthritis
Survey, Family Life
Complementary Therapies
Pain
Keywords: Knee Osteoarthritis
pain
Complementary Therapies
Survey
questionnaire
Lead sponsor: Frederiksberg University Hospital
Sponsor class: OTHER
First posted: 2018-03-21
Enrollment: 9600
Sex: ALL
Minimum age (years): 60
Maximum age (years): 69
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population will comprise the sample of all elderly individuals 60-69 years old, living in the Frederiksberg municipality (central part of Copenhagen) Denmark

Brief summary: Although knee pain is prevalent among community-dwelling older adults, little is known about how people in general handle their pain. We will conduct a survey to explore how knee pain affects people's lives and which treatments or self-management strategies they have chosen (or are being offered), and how these interact concerning pain reduction and maintenance of function.

Detailed description: Although knee pain is prevalent among community-dwelling older adults and frequently leads to consultation in primary care, little is known about how people in general manage their knee pain.

Treatments of knee osteoarthritis include a variety of non-pharmaceutical, medical, and surgical interventions with highly individual and inconsistent results and with the possible exception of a longer lasting weight reduction, none of the non-surgical treatments have been able to demonstrate long-lasting effect on pain or disability.

It is well recognised that patient participation in handling of disease creates better compliance and satisfaction with pharmacological treatment.

Another option for taking active part in self-management is the use of complementary and alternative medicine (CAM). despite their popularity and effect, there is currently no overview of the actual extent of CAMs used for knee pain and disability at a population level, and most CAMs remain to be studied scientifically for efficacy.

The incidence of knee OA shows a steep increase at age above 60 years. Furthermore, after this age an increasing prevalence of disablement to knee trouble is encountered. To prevent this development, measures must be sought to alter the course of knee OA.

By asking people about how knee pain affects their life, which treatments or self-management strategies they have chosen (or are being offered), and how these interact for the reduction of pain and maintenance of function, new knowledge will be gained about the preferences and perceived effectiveness of treatments at large. The information gained will enable the prioritising of research on interventions to be tested and will align this with the primary concerns and interests of the population. This will subsequently lead to better guidance of patients by the health care providers, and will aid decision makers in choosing feasible health care policies and strategies.

Eligibility criteria: Inclusion Criteria:

* Between 60-69 years of age
* Citizen in the Community of Frederiksberg

Exclusion Criteria:

• No formal exclusion criteria but unability to understand/answer our questionnaire is per se an exclusion criteria

Primary outcomes:
measure: Self-disclosed knee trouble/pain
timeFrame: 1 Year
Secondary outcomes:
measure: Self-disclosed knee trouble/pain
timeFrame: Annually for 10 years
measure: Knee injury and Osteoarthritis Outcome Score (KOOS)
timeFrame: Annually for 10 years
measure: Brief Illness Perception Questionnaire (IPQ-B)
timeFrame: Annually for 10 years
measure: EQ-5D
timeFrame: Annually for 10 years
measure: Treatments of all kinds
timeFrame: Annually for 10 years
measure: Influence of treatments (longitudinal)
timeFrame: Annually for 10 years
Other outcomes:
Locations:
city: Frederiksberg
country: Denmark
facility: the Parker Institute, Bispebjerg-Frederiksberg Hospital
state: Danmark
Study officials:
affiliation: The Parker Institute
name: Elisabeth Ginnerup
role: STUDY_CHAIR
References:
citation: Ginnerup-Nielsen EM, Henriksen M, Christensen R, Heitmann BL, Altman R, March L, Woolf A, Karlsen H, Bliddal H. Prevalence of self-reported knee symptoms and management strategies among elderly individuals from Frederiksberg municipality: protocol for a prospective and pragmatic Danish cohort study. BMJ Open. 2019 Sep 4;9(9):e028087. doi: 10.1136/bmjopen-2018-028087.