Clinical trial NCT06036134: Reducing COVID-19 Vaccine Hesitancy Among Hispanic Parents
Official title: Reducing Vaccine Hesitancy Among Hispanic Parents of COVID-19 Vaccine-Eligible Children
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Vaccine-Preventable Diseases
COVID-19 Pandemic
Health-Related Behavior
Health Knowledge, Attitudes, Practice
Narration
Keywords: COVID-19 Vaccine
Digital storytelling
Hispanic children
Vaccine hesitancy
Health disparities
Lead sponsor: Arizona State University
Sponsor class: OTHER
Collaborators: name: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
First posted: 2023-09-13
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: COVID-19 vaccines are available to children over six months, and these vaccines are powerful tools against this catastrophic pandemic. However, Hispanic/Latino children have lower COVID-19 vaccination rates than White non-Hispanic children .Our team of health communication and public health experts proposes a community-based theory-driven intervention that utilizes culturally-grounded narratives from digital storytelling to reduce Hispanic parents' COVID-19 vaccine hesitancy and increase their children's vaccine uptake.

Detailed description: Among children and adolescents, infection with SARS-CoV-2 (COVID-19) can lead to health complications (e.g., multisystem inflammatory syndrome, long COVID), hospitalizations, and death. COVID-19 vaccines are available to children over six months, and these vaccines are powerful tools against this catastrophic pandemic. However, Hispanic/Latino children have lower COVID-19 vaccination rates than White non-Hispanic children3 In most southwestern U.S. states, Hispanic children have the lowest COVID-19 vaccination rates among pediatric populations. Lower vaccination rates in children are primarily due to parental vaccine hesitancy. Considerably more work is needed to decrease parental COVID-19 vaccine hesitancy among Hispanic parents.

Narrative-based interventions are powerful tools for persuading individuals to enact health behaviors (vaccination) that require an immediate personal cost (discomfort) for a longer-term gain (disease immunity). Our current study will examine digital storytelling (DST), a specific form of culturally-grounded narrative developed via community engagement, to reduce Hispanic parents' COVID-19 vaccine hesitancy. No research, to our knowledge, has used digital stories to decrease Hispanic parents' vaccine hesitancy. Therefore, it is critical to assess which stories resonate with and are most persuasive for those who are hesitant to have their children receive COVID-19 doses and then explore the impact of an intervention utilizing these stories on parents' decisions to vaccinate their children against COVID-19.

Specific Aims:

Aim 1: Develop one digital story per participant (n=10; each story lasting 2-3 minutes) in a DST workshop with a sample of Hispanic parents/ legal guardians converted from being COVID-19 vaccine-hesitant to vaccine-accepting.

Aim 2: Assess the feasibility and acceptability of a web-based pilot DST intervention vs. an information-only control among Hispanic parents and legal guardians (n=80) of children who are not up-to-date with CDC-recommended COVID-19 vaccine doses.

Exploratory aim: The investigators will explore intervention and control group participants' (n=80) patterns of pre- to post-intervention change in vaccine uptake perceptions, vaccine hesitancy, intentions to vaccinate children against COVID-19, and children's vaccine uptake at two months post-intervention.

Eligibility criteria: Inclusion Criteria:

* self-identifies as Hispanic
* is a biological parent or a legal guardian of at least one child under 18 years old
* their child(ren) are not vaccinated against up-to-date with COVID-19 vaccine doses
* agrees to send and receive a text message and submit a photo of their child's immunization record for T3 data collection.

Exclusion Criteria:

* individuals who do not meet inclusion criteria or are unable/ unwilling to provide consent.

Primary outcomes:
measure: Parental COVID-19 vaccine hesitancy
timeFrame: Baseline (T1), T2 (after 4-week intervention), and T3 (2-months post-intervention)
measure: Intentions to vaccinate child(ren) against COVID-19
timeFrame: Baseline (T1), T2 (after 4-week intervention), and T3 (2-months post-intervention)
measure: Child's COVID-19 vaccine uptake
timeFrame: T3 (2-months post-intervention)
Secondary outcomes:
measure: Parents' attitudes about vaccinating their child(ren) against COVID-19
timeFrame: Baseline (T1), T2 (after 4-week intervention), and T3 (2-months post-intervention)
measure: Parents' perceived norms about vaccinating their child(ren) against COVID-19
timeFrame: Baseline (T1), T2 (after 4-week intervention), and T3 (2-months post-intervention)
measure: Parents' perceived behavioral control to vaccinate their child(ren) against COVID-19
timeFrame: Baseline (T1), T2 (after 4-week intervention), and T3 (2-months post-intervention)
Other outcomes:
Locations:
city: Phoenix
country: United States
facility: Arizona State University
state: Arizona
Study officials:
affiliation: Arizona State University
name: Alexis Koskan, Ph.D
role: PRINCIPAL_INVESTIGATOR
affiliation: Arizona State University
name: Sunny W Kim, Ph.D
role: PRINCIPAL_INVESTIGATOR
References: