Clinical trial NCT06065696: Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery
Official title: Compliance With Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery in Tertiary Hospital in Indonesia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Enhanced Recovery After Surgery
Anesthesia
Surgery-Complications
Colorectal
Early Mobilization
Keywords: early mobilization
Enhanced Recovery After Surgery
PONV prophylaxis
fluid management
pain management
Lead sponsor: Indonesia University
Sponsor class: OTHER
First posted: 2023-10-04
Enrollment: 343
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients underwent colorectal surgery in Cipto Mangunkusumo Hospital during 2020 to 2022

Brief summary: Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our hospital: post operative nausea and vomiting (PONV) prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management. Although early mobilization affected by postoperative pain, vomiting and nausea, and fluid balance management, nonetheless, there is no clear evidence of how much each of these components will affect early mobilization.

Detailed description: Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in ERAS protocol for colorectal surgery in our hospital: PONV prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management. Although early mobilization affected by postoperative pain, vomiting and nausea, and fluid balance management, nonetheless, there is no clear evidence of how much each of these components will affect early mobilization. This study was a retrospective cohort study by collecting secondary data from patients underwent elective colorectal surgery in our hospital from January 2020 to December 2022. The outcomes assessed were early mobilization rate and factors affecting it (PONV prophylaxis, intraoperative fluid management, intraoperative multimodal analgesia, and postoperative opioid-free pain management).

Eligibility criteria: Inclusion criteria

* Patient underwent colorectal surgery in Cipto Mangunkusumo Hospital from 2020 to 2022
* Age 18-60 years old
* American Society of Anesthesiologist (ASA) physical status 1, 2, and 3

Exclusion criteria

* Patients who were not intubated on postoperative period
* Patients who had physical limitation during preoperative mobility test

Primary outcomes:
measure: Early mobilization
timeFrame: Within 24 hours after surgery
measure: PONV prophylaxis
timeFrame: Given during intraoperative period
measure: Multimodal analgesia
timeFrame: Given during intraoperative period
measure: Intraoperative fluid management
timeFrame: Given during intraoperative period
measure: Postoperative pain management
timeFrame: Immediately after surgery until discharge, assessed until hospital discharge, up to 50 days
Secondary outcomes:
Other outcomes:
Locations:
city: Jakarta Pusat
country: Indonesia
facility: Cipto Mangunkusumo Central National Hospital
state: DKI Jakarta
Study officials:
affiliation: Indonesia University
name: Aldy Heriwardito, Consultant
role: PRINCIPAL_INVESTIGATOR
References: