Clinical trial NCT05593796: Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder
Official title: The Efficacy of Cognitive Behavioral Therapy(CBT) in Treatment of Methamphetamine Use Disorder
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Methamphetamine Abuse
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2022-10-25
Enrollment: 50
Sex: MALE
Minimum age (years): 15
Maximum age (years): 50
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: In phase 0:

. These patients will undergo toxicological and psychiatric assessment and will be screened using the inclusion and exclusion criteria.

phase 1:

treatment-as-usual (TAU)- Group offered usual treatment include detoxification, medical care. Clinician-delivered CBT-Group offered 12 weekly, individual sessions of manual-guided CBT (15) delivered by trained clinician .

phase2: a follow-up at 3-month post treatment phase without treatment.
Primary purpose: TREATMENT

Brief summary: The efficacy of cognitive behavioral therapy(CBT) in treatment of methamphetamine use disorder

Detailed description: Methamphetamine (MA) use is a serious public health concern in many countries and is second to cannabis as the most widely abused illicit drug in the world.

Over the past few years; there is an alarming increase in crystal methamphetamine (Shabu) abuse in the Egyptian market and The Egyptian government is annoyed from this issue because youth within the age of productivity were targeted.

Regular methamphetamine use can be associated with a range of psychiatric symptoms, particularly psychosis, anxiety, and depression.

No FDA approved pharmacological treatments are available for Meth addiction up till now and despite great advances achieved in understanding the neurobiology of drug addiction, the therapeutic options are severely limited . Consequently, the only available treatment at present is psychosocial intervention.

The effectiveness of CBT for other substance-use disorders (e.g. alcohol-, opioid- and cocaine-use disorders) has been well documented and as such this basic treatment approach has been applied to amphetamine-type stimulant (ATS)-use disorder .

Currently, there is not enough evidence to establish the efficacy of CBT for amphetamine -type stimulant( ATS) -use disorders because of a paucity of high-quality research in this area.

The present study will examine the efficacy of Cognitive behavioral therapy in reducing methamphetamine use in comparison to medical treatment usually taken in methamphetamine use disorder

Eligibility criteria: Inclusion Criteria:

* patients who meet the criteria for methamphetamine use disorder according to Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM 5) (10)
* aged of 15-49 years' old
* more than 9 year of education
* urine drug screening positive for methamphetamine

Exclusion Criteria:

* other Axis I disorder of DSM-V criteria such as bipolar disorder, schizophrenia, depression
* Had a legal case pending resulting in inability to commit to 12 weeks of treatment.
* Refusal to participate
* poly drug dependence.

Primary outcomes:
measure: increase in the addiction severity index for methamphetamine use disorder
timeFrame: 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References: