louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT04050241: Workload in Anesthesiological Practice
Official title: Objective and Subjective Mental Workload During Direct and Indirect Laryngoscopy in Anesthetists: an In-vivo, Cross-over Randomized Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Work Related Stress
Keywords: Mental workload
Anesthesia
Laryngoscopy
Intubation
Perceived workload
Lead sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Sponsor class: OTHER
First posted: 2019-08-08
Enrollment: 14
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: SUPPORTIVE_CARE

Brief summary: The study evaluates differences in perceived and objective workload in anesthetists during intubation procedure with a direct (Mcintosh) or indirect (Glidescope) laryngoscope. Expert anesthetists will perform 3 intubations per device, while completing a secondary task, during which reaction times to an auditory stimulus will be recorded, and will complete a questionnaire (the NASA-Task Load Index) to evaluate their perceived workload at the end of each procedure.

Detailed description: Intubation and laryngoscopy are the most demanding procedure in anesthesiological routine clinical practice, associated with high workload. The measurement and management of workload is considered important in anesthesiology to prevent work-related stress and errors in performance. New devices, thanks to advances in technology, seem promising in reducing operators' workload and improving safety and success of intubation processes.

Therefore, in this study, based on previous results, the hypothesis that the Glidescope videolaryngoscope reduces operators' perceived and and objective workload, as compared to the standard Mcintosh laryngoscope, will be tested.

Expert anesthetists will perform 3 intubations per device in a randomized order, while completing a secondary task, during which reaction times (verbal responses) to an auditory stimulus (a clacson) will be recorded, and operators will complete a questionnaire (the NASA-Task Load Index) to evaluate their perceived workload at the end of each procedure.

Eligibility criteria: Inclusion Criteria:

* Anesthetists with expertise in videolaryngoscopy and direct laryngoscopy that give consent to participate

Exclusion Criteria:

* Anesthetists that refuse to participate
* Anesthetists without expertise in videolaryngoscopy and direct laryngoscopy that give consent to participate
* Anesthetists that have left hearing loss

Primary outcomes:
measure: Perceived workload
timeFrame: Immediately after the procedure/intervention
Secondary outcomes:
measure: Quantitative workload
timeFrame: During the laryngoscopy/intubation procedure
Other outcomes:
Locations:
city: Milan
country: Italy
facility: Fondazione IRCCS Istituto Neurologico Carlo Besta
Study officials:
affiliation: Fondazione IRCCS Istituto Neurologico Carlo Besta
name: Elenora F Orena, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05096741: OCS Liver PROTECT Continuation Post-Approval Study
Official title: OCS Liver PROTECT Continuation Post-Approval Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Liver Transplant
Lead sponsor: TransMedics
Sponsor class: INDUSTRY
First posted: 2021-10-27
Enrollment: 300
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Subjects transplanted in the OCS Liver PROTECT Trial

Brief summary: Post-approval observational study of subjects that were enrolled and transplanted in the OCS Liver PROTECT Trial.

Detailed description: Post-approval observational study of subjects that were enrolled and transplanted in the OCS Liver PROTECT Trial.

Eligibility criteria: Inclusion Criteria:

* Subjects transplanted in the OCS Liver PROTECT Trial

Primary outcomes:
measure: Liver Graft Survival
timeFrame: 2 years
Secondary outcomes:
Other outcomes:
measure: Patient Survival
timeFrame: 2 years
Locations:
city: La Jolla
country: United States
facility: University of California San Diego
state: California
city: San Diego
country: United States
facility: Scripps
state: California
city: San Francisco
country: United States
facility: University of California San Francisco
state: California
city: Tampa
country: United States
facility: Tampa General
state: Florida
city: Atlanta
country: United States
facility: Emory
state: Georgia
city: Baltimore
country: United States
facility: Johns Hopkins
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
city: Detroit
country: United States
facility: Henry Ford Hospital
state: Michigan
city: Minneapolis
country: United States
facility: University of Minnesota
state: Minnesota
city: Columbus
country: United States
facility: Ohio State University Medical Center
state: Ohio
city: Memphis
country: United States
facility: University of Tennessee Health Science Center
state: Tennessee
city: Dallas
country: United States
facility: University of Texas Southwest
state: Texas
city: Houston
country: United States
facility: Houston Methodist Hospital
state: Texas
city: San Antonio
country: United States
facility: The University of Texas Health Science Center at San Antonio
state: Texas
city: Charlottesville
country: United States
facility: University of Virginia
state: Virginia
city: Richmond
country: United States
facility: Virginia Commonwealth University Health System
state: Virginia
city: Seattle
country: United States
facility: University of Washington
state: Washington
Study officials:
References:
Clinical trial NCT06677541: Vibrator Use to Improve Sexual and Pelvic Floor Function Among Urogynecology Patients
Official title: Vibrator Use to Improve Sexual and Pelvic Floor Function Among Urogynecology Patients
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Pelvic Floor Dysfunction
Sexual Dysfunction Female
Vibrator
Lead sponsor: Albany Medical College
Sponsor class: OTHER
First posted: 2024-11-06
Enrollment: 84
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Limited data exist describing the use and role of vibrators in a urogynecology population and no randomized controlled trials investigating the use of vibrators as a therapeutic tool to enhance sexual and pelvic floor function in urogynecology patients has been conducted. This study aims to evaluate the efficacy of vibrator use in improving sexual and pelvic floor function in urogynecology patients who report sexual dysfunction.


Eligibility criteria: Inclusion Criteria:

* • Women aged 18 and over presenting to the urogynecology clinic.

  * Women diagnosed with one of the following urogynecologic conditions

    o Pelvic organ prolapse, urgency incontinence, overactive bladder, stress urinary incontinence, fecal incontinence, recovering from a urogynecologic surgery over 6 weeks following surgery and clear for intercourse. Patients post op who continue to have pelvic floor dysfunction can be candidates for the study if they continue to have one of the pelvic floor dysfunctions listed.
  * Patient will be screened with the FSFI and will be eligible if they score less than 26.55
  * Patient's must be willing to use a vibrator.
  * Able to provide informed consent.
  * Not currently using a vibrator or has not used a vibrator in the past 3 months.
  * Able to read and write in English

Exclusion Criteria:

* • Patients with cognitive impairment.

  * Patients with refusal or discomfort with vibrator use.
  * Currently using a vibrator or has used a vibrator in the past 3 months.
  * Patients unable to provide informed consent.
  * Patients not clear for intercourse following their surgery
  * Patients with surgery within 2 months of recruitment.

Primary outcomes:
measure: Female Sexual Function Index
timeFrame: up to 12 weeks
Secondary outcomes:
measure: Pelvic Floor Distress Inventory -20
timeFrame: up to 12 weeks
measure: Pelvic Organ Prolapse incontinence sexual questionnaire 12
timeFrame: up to 12 weeks
measure: sexual satisfaction index
timeFrame: up to 12 weeks
measure: female genitourinary pain index
timeFrame: up to 12 weeks
measure: patient health questionnaire 9
timeFrame: up to 12 weeks
Other outcomes:
Locations:
city: Albany
country: United States
facility: Albany Medical Center
state: New York
Study officials:
References:
Clinical trial NCT03730441: Correlation Between ADR of Screening and All Colonoscopies
Official title: Correlation Between ADR of Screening and All Colonoscopies
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Colon Neoplasm
Lead sponsor: Hospital Frydek-Mistek
Sponsor class: OTHER
First posted: 2018-11-05
Enrollment: 6925
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: people over 50 years of age coming for colonoscopic examination

Brief summary: The aim of the study is to compare ADR for colonoscopies from various indications and to find correlations between ADR of screening and all examinations.

Detailed description: ADR (adenoma detection rate) is generally accepted quality indicator and it is calculated from screening colonoscopies in patients over 50 years of age. For possible gaming with ADR for screening colonoscopies, monitoring of ADR for all colonoscopies is discussed nowadays.The aim of the study is to compare ADR for colonoscopies from various indications and to find correlations between ADR of screening and all examinations.

We want to retrospectively assess the quality indicators of all colonoscopies performed from January 2013 to December 2017. We want to calculate ADR for all colonoscopies in patients over 50 years of age excluding therapeutic, IBD, management of complications and sigmoidoscopies (screening, surveillance, diagnostic) and separately only for screening colonoscopies. Correlation analysis will be performed using Pearson´s correlation coefficient.

Eligibility criteria: Inclusion Criteria:

* people over 50 years of age coming for colonoscopic examination (screening, surveillance, diagnostic)

Exclusion Criteria:

* age under 50 years
* indication for colonoscopy: therapeutic, IBD, management of complications and sigmoidoscopies

Primary outcomes:
measure: correlation between ADR of screening and all colonoscopies (screening, surveillance, diagnostic)
timeFrame: january 2013 - december 2017
Secondary outcomes:
Other outcomes:
Locations:
city: Frýdek-Místek
country: Czechia
facility: Hospital Frydek-Mistek
Study officials:
affiliation: Doctor
name: Ivana Mikoviny Kajzrlikova
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mikoviny Kajzrlikova I, Vitek P, Chalupa J, Kuchar J, Platos J, Reha P, Klvana P. Correlation between ADR of screening and all colonoscopies. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Nov;165(4):386-389. doi: 10.5507/bp.2020.059. Epub 2020 Dec 16.
Clinical trial NCT06596941: Ultrasound Assessment of Isolated Distal Deep Vein Thrombosis
Official title: Ultrasound Assessment of Isolated Distal Deep Vein Thrombosis
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Iddvt
Pulmonary Embolism (PE)
Lead sponsor: Ruijin Hospital
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 800
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Both male and female

Brief summary: Retrospective assessment of ultrasound and clinical characteristics of patients with IDDVT, development of a pulmonary embolism risk prediction model for thrombus, and provision of appropriate diagnostic and therapeutic recommendations.


Eligibility criteria: Inclusion Criteria:

Diagnosis of new-onset IDDVT confirmed by lower limb vascular ultrasound; presence/absence of pulmonary embolism clarified by pulmonary artery CTA; ultrasound and pulmonary artery CTA results spanning no more than 5 days.

Exclusion Criteria:

Anticoagulation therapy in the last month; pregnancy or puerperium; recurrent DVT or PE.

Primary outcomes:
measure: IDDVT with PE
timeFrame: At the initial visit
Secondary outcomes:
Other outcomes:
Locations:
city: Shanghai
country: China
facility: Ruijin Hospital,Shanghai Jiao Tong University School of Medicine
Study officials:
References:
Clinical trial NCT04459741: HIV, Immune Activation and Salt Sensitive Hypertension
Official title: Hypertension, Dietary Salt and Inflammation
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: HIV-1-infection
Hypertension,Essential
Keywords: Inflammation
Human immunodeficiency virus (HIV)
Salt
Interleukin 6
Interleukin 17A
Hypertension
Lead sponsor: Mulungushi University
Sponsor class: OTHER
Collaborators: name: University of Zambia
name: Vanderbilt University Medical Center
First posted: 2020-07-07
Enrollment: 85
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Participants are instructed on salt deprivation for a week followed by a low salt (4 grams) diet for one week and switched to high salt (9 grams) for the following one week
Primary purpose: DIAGNOSTIC

Brief summary: High dietary salt is associated with immune activation, elevated levels of inflammatory cytokines and hypertension in murine models. Hypertension is independently associated with inflammation in both murine studies and studies in humans. In people living with HIV, these interactions are not well established. The aim of this study is to determine the effect of excess dietary salt on immune cell activation, pro- and anti-inflammatory cytokines and blood pressure between individuals with and without hypertension among people living with HIV and HIV negative persons.


Eligibility criteria: Inclusion Criteria:

* Adults (aged 18 and above) who will be required to verbally consent and sign a consent form
* HIV positive or HIV Normotensive individuals or hypertensive If HIV, on antiretroviral therapy ART treated hypertensive individuals

Exclusion Criteria:

* Existence of comorbidities such as diabetes mellitus and cancer Existing and recent past opportunistic infections, syphilis, hepatitis C and B virus infection and tuberculosis infection;
* Sick persons (clients seeking healthcare due to an illness rather than routine ART clinic reviews)
* Those with recent and current alcohol consumption and smoking status

Primary outcomes:
measure: Pro-inflammatory cytokines
timeFrame: 2 weeks: At the end of the low- and high-salt phases
Secondary outcomes:
measure: Blood pressure
timeFrame: 2 weeks: At the end of the low- and high-salt phases
Other outcomes:
Locations:
city: Livingstone
country: Zambia
facility: Livingstone Central Hospital
state: Southern
Study officials:
affiliation: Mulungushi University
name: Sepiso K Masenga, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Masenga SK, Hamooya BM, Nzala S, Kwenda G, Heimburger DC, Mutale W, Koethe JR, Kirabo A, Munsaka SM. HIV, immune activation and salt-sensitive hypertension (HISH): a research proposal. BMC Res Notes. 2019 Jul 16;12(1):424. doi: 10.1186/s13104-019-4470-2.
Clinical trial NCT04934241: The Effect of Self-Acupressure on Pain and Sleep in Coronary Artery Patients
Official title: The Effect of Self-Acupressure on Pain and Sleep in Coronary Artery Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Coronary Artery Disease
Keywords: Self-Acupressure
Sleep
Pain
Coronary Artery Patıent
Lead sponsor: Istanbul Sabahattin Zaim University
Sponsor class: OTHER
First posted: 2021-06-22
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: This study is an experimental study with pre-test and post-test control groups
Primary purpose: SUPPORTIVE_CARE

Brief summary: This study will be conducted to evaluate the effect of acupressure applied to patients with coronary artery disease (CAD) on pain and sleep quality.

Detailed description: Self-Acupressur application will improve pain and sleep quality in CAD.

Eligibility criteria: Inclusion Criteria:

* Not having a psychiatric diagnosis,
* To be able to communicate adequately
* Not having psychiatric problems
* Volunteering to participate in research

Exclusion Criteria:

* None

Primary outcomes:
measure: Visual Analog Scale (VAS)
timeFrame: 1. week
measure: Visual Analog Scale (VAS)
timeFrame: 4. week
measure: Pittsburgh Sleep Quality Index (PSQI)
timeFrame: 1. week
measure: Pittsburgh Sleep Quality Index (PSQI)
timeFrame: 4. week
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Sabahattin Zaim University, Faculty of Health Sciences
state: Küçükçekmece
Study officials:
affiliation: Istanbul Sabahattin Zaim University
name: Zülfünaz ÖZER, PhD
role: STUDY_CHAIR
References:
citation: Narimani M, Ansari Jaberi A, Negahban Bonabi T, Sadeghi T. Effect of Acupressure on Pain Severity in Patients Undergoing Coronary Artery Graft: A Randomized Controlled Trial. Anesth Pain Med. 2018 Oct 20;8(5):e82920. doi: 10.5812/aapm.82920. eCollection 2018 Oct.
Clinical trial NCT00527241: Efficacy Trial of Raices Nuevas
Official title: Efficacy Trial of Raices Nuevas
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
PHASE3
Conditions: Intimate Partner Violence
Keywords: partner violence, spouse abuse
Lead sponsor: Centers for Disease Control and Prevention
Sponsor class: FED
Collaborators: name: University of Michigan
name: The Community Health and Social Services Center, Inc.
First posted: 2007-09-10
Enrollment: 160
Sex: MALE
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This trial will test the impact of a culturally tailored and theory driven primary intimate partner violence prevention intervention with Spanish speaking Latino men.

Detailed description: In this randomized controlled trial, Spanish speaking Latino men will be recruited from community church settings in Southwest Detroit and randomly assigned to: (a) an intimate partner violence prevention intervention or (b) a wait-list control condition. Latino men assigned to the intervention will receive, in a small group setting, an 8-session, primary intimate partner violence prevention intervention based on the Duluth model and culturally and linguistically tailored for Spanish speaking Latino men. Measures will be administered at pre-test, and at three and six months post-intervention.

Eligibility criteria: Inclusion Criteria:

* Spanish speaking Latino men
* between the ages of 18 and 55
* in a stable relationship for at least the past three months

Exclusion Criteria:

* severely mentally impaired
* hearing impaired

Primary outcomes:
measure: Perpetration of violence towards intimate partner
timeFrame: 3 and 6 months after completion of intervention
Secondary outcomes:
measure: intentions to abuse intimate partner
timeFrame: 3 and 6 months after completion of intervention
measure: Beliefs, norms, and perceived self-efficacy
timeFrame: 3 and 6 months after completion of intervention
Other outcomes:
Locations:
city: Detroit
country: United States
facility: Community Health and Social Services Center (CHASS)
state: Michigan
Study officials:
References:
Clinical trial NCT00748241: Study to Evaluate Implant Survival Rate of Astra Tech Fixture ST in the Posterior Maxilla With One-stage Surgery and Early Loading
Official title: An Open Prospective Study to Evaluate the Survival Rate and Marginal Bone Response of Astra Tech Dental Implants, Fixture ST, in Patients With Tooth Loss in the Posterior Maxilla.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Jaw, Edentulous, Partially
Lead sponsor: Dentsply Sirona Implants and Consumables
Sponsor class: INDUSTRY
First posted: 2008-09-08
Enrollment: 19
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The purpose of this study is primarily to evaluate implant survival rate of Astra Tech Fixture ST placed in the posterior maxilla. A one-stage surgical protocol will be used and the implants will be loaded four weeks after implant installation (early loading). Marginal bone levels, plaque and status of the periimplant mucosa will also be evaluated. The subjects will be followed for three years.


Eligibility criteria: Inclusion Criteria:

* Age 18 - 75
* Unilateral or bilateral edentulism in the posterior maxilla, last tooth should be the canine or the first bicuspid
* Willing to give informed consent

Exclusion Criteria:

* Bone height \< 5 mm, in the planned implant area
* Bone width \< 5 mm, in the planned implant area
* Previous bone augmentation procedure in the planned implant area
* Previous failures of endosseous implants
* Untreated caries and/or periodontal disease of residual dentition
* History or presence of any systemic or local disease or condition that would compromise post-operative healing and/or osseointegration
* Systemic corticosteroids or any other medication that would compromise post-operative healing and/or osseointegration
* Current alcohol or drug abuse
* Unable or unwilling to return for follow-up visits for 3 years

Primary outcomes:
measure: Implant Survival Rate
timeFrame: At follow-up visit: 6 months after implants have been loaded
measure: Implant Survival Rate
timeFrame: At follow-up visit: 1 year after implants have been loaded
measure: Implant Survival Rate
timeFrame: At follow-up visit: 2 years after implants have been loaded
measure: Implant Survival Rate
timeFrame: At follow-up visit: 3 years after implants have been loaded
Secondary outcomes:
measure: Implant Failure
timeFrame: 3 years after implant placement
Other outcomes:
Locations:
city: New York
country: United States
facility: Dept. of Periodontology, New York Dept of Veterans Affairs Medical Center
state: New York
city: New York
country: United States
facility: Dept. of Prosthodontics, New York Dept of Veterans Affairs Medical Center
state: New York
Study officials:
affiliation: New York Dept of Veterans Affairs Medical Center
name: Bruce G Valauri, D.D.S.
role: PRINCIPAL_INVESTIGATOR
affiliation: New York Dept of Veterans Affairs Medical Center
name: Michael Toffler, D.D.S.
role: PRINCIPAL_INVESTIGATOR
References: