louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06461000: EULAR Impact of Rheumatic and Musculoskeletal Diseases Survey
Official title: EULAR Impact of Rheumatic and Musculoskeletal Diseases Survey
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Rheumatologic Disease
Musculoskeletal Diseases
Lead sponsor: European Alliance of Associations in Rheumatology
Sponsor class: OTHER
First posted: 2024-06-14
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: - adults with at least 1 RMD

Brief summary: The EULAR Impact of RMDs Survey collects first-hand information about the impact of rheumatic and musculoskeletal diseases (RMDs) among patients across and beyond Europe. Through periodic questionnaires, patients will provide information about their healthcare situation, and how the disease affects their social and occupational lives. This data will be an important resource for researchers, healthcare professionals, and patients alike, providing valuable insights into the burden of disease and helping improve the overall care for people living with these conditions.


Eligibility criteria: Inclusion Criteria:

* 18-year-old at time of baseline survey
* Living in a EULAR country at time of baseline survey
* Diagnosed with at least one RMD
* Valid personal e-mail address
* Being able to use an internet website

Exclusion Criteria:

* none

Primary outcomes:
measure: General population description - country
timeFrame: every 6 months for up to 5 years
measure: General population description - diagnosis
timeFrame: every 6 months for up to 5 years
measure: General population description
timeFrame: every 6 months for up to 5 years
Secondary outcomes:
measure: Diagnosis history - physician treating the RMD
timeFrame: every 6 months for up to 5 years
measure: Diagnosis history - outpatient care history
timeFrame: every 6 months for up to 5 years
measure: Diagnosis history - timeline
timeFrame: every 6 months for up to 5 years
measure: Diagnosis history - Inpatient care
timeFrame: every 6 months for up to 5 years
measure: Non-pharmacological and pharmacological treatments.
timeFrame: every 6 months for up to 5 years
measure: Other chronic diseases
timeFrame: every 6 months for up to 5 years
measure: Disease burden - impact of disease
timeFrame: every 6 months for up to 5 years
measure: Disease burden - health assessment
timeFrame: every 6 months for up to 5 years
measure: Disease burden - quality of life
timeFrame: every 6 months for up to 5 years
measure: Consequences on work and life (WPAI questionnaire)
timeFrame: every 6 months for up to 5 years
measure: Other barriers due to RMD
timeFrame: every 6 months for up to 5 years
measure: Health care
timeFrame: every 6 months for up to 5 years
measure: Demographics - persons living with patient
timeFrame: every 6 months for up to 5 years
measure: Demographics - professional status
timeFrame: every 6 months for up to 5 years
Other outcomes:
Locations:
city: Kilchberg
country: Switzerland
facility: EULAR
state: Zurich
Study officials:
References:
Clinical trial NCT03471000: The Influence of the Crown-implant Ratio on the Crestal Bone Level and Implant Secondary Stability
Official title: The Influence of the Crown-implant Ratio on the Crestal Bone Level and Implant Secondary Stability - 36 Months Clinical Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Partial Edentulism
Tooth Loss
Keywords: implant
dental implant
Lead sponsor: Akademicka Poliklinika Stomatologiczna
Sponsor class: OTHER
Collaborators: name: Dentsply Sirona Implants and Consumables
name: Wrocław Medical University
First posted: 2018-03-20
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study was to determine whether implant length and the crown-to-implant (C/I) ratio influence implant stability and the loss of the surrounding marginal bone, and whether short implants can be used instead of sinus augmentation procedures.

Detailed description: The patients participating in the study (n=30) had one single tooth implant - a short (OsseoSpeed™ L6Ø4 mm, Implants) or a regular implant (OsseoSpeed™ L11 and L13Ø4 mm, DENTSPLY Implants) - placed in the maxilla. The evaluation was based on clinical and radiological examination.

The crown-to-implant ratio was determined by dividing the length of the crown together with the abutment by the length of the implant placed crestally. Mean crown-to-implant ratios were calculated separately for each group and its correlation with the MBL (marginal bone loss) and stability was assessed. The authors compared the correlation between the C/I ratio values, MBL and secondary implant stability.

Eligibility criteria: Inclusion Criteria:

* Non-smoking patients with no systemic or local diseases were qualified.

Additional inclusion criteria were as follows:

* minimal apicocoronal height of the alveolar ridge of 6 mm in the region of the implant insertion in the pre-surgical qualification
* minimal width of the alveolar ridge of 6-7 mm in the region of interest
* HKT (height of the keratinized tissue) higher than 2 mm
* API ≤ 35 (Approximal Plaque Index)
* PI ≤ 25. (Plaque Index)
* Bone Type III or D2 were included in the study
* No graft procedures in the area of interest,

Exclusion Criteria:

-

Primary outcomes:
measure: Clinical measurement of implant stability
timeFrame: 36 months
Secondary outcomes:
measure: Radiological measurement of marginal bone loss around implant
timeFrame: 36 months
Other outcomes:
Locations:
Study officials:
affiliation: Medical University Wrocław
name: Marzena Dominiak, Prof
role: PRINCIPAL_INVESTIGATOR
References:
citation: Hadzik J, Krawiec M, Slawecki K, Kunert-Keil C, Dominiak M, Gedrange T. The Influence of the Crown-Implant Ratio on the Crestal Bone Level and Implant Secondary Stability: 36-Month Clinical Study. Biomed Res Int. 2018 May 16;2018:4246874. doi: 10.1155/2018/4246874. eCollection 2018.
Clinical trial NCT01544400: Description and Evaluation of Eating Disorders in Elite Athletes (TCA SHN)
Official title: Description and Evaluation of Eating Disorders in Elite Athletes
Study type: OBSERVATIONAL
Overall status: TERMINATED
Conditions: Eating Disorders
Anorexia Nervosa
Boulimia Nervosa
Binge Eating Disorders
Keywords: reverse anorexia,
anorexia athletics
Lead sponsor: Nantes University Hospital
Sponsor class: OTHER
First posted: 2012-03-05
Enrollment: 386
Sex: ALL
Minimum age (years): 12
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Athletes registered on the high level sportsmen list or in access to high level sport

Brief summary: Athletes in particular elite athletes have obsessional food and body concerns, in bond with a worship of the performance more and more invading, which lead to clinical and subclinical eating disorders. These eating disorders differ according to the disciplines and are difficult to diagnose in athletes because there are insufficiently described.

Our aim at estimating the frequency of eating disorders in athletes and describing eating disorders by means of somatic, dietetic and psychological evaluations.


Eligibility criteria: Inclusion Criteria:

* to have at least 12 years
* to be registered on the high level sportsmen list or to be in access to high level sport
* to have obtained the non opposition of the athlete if he is major (if not the legal person in charge of the athlete have to give is non opposition).
* to be affiliated to social security

Exclusion Criteria:

* presenting obvious cognitive disturbance
* not able to understand or/ and to read French language
* pregnant women
* subject under tutelage

Primary outcomes:
measure: Presence of eating disorder
timeFrame: 1 day
Secondary outcomes:
measure: Presence of eating disorder according to the psychologist, dietician and the somatician
timeFrame: 1 day
measure: Sociodemographic variables
timeFrame: 1 day
measure: Doping conduits variables
timeFrame: 1 day
measure: Investment in practice sporting variables
timeFrame: 1 day
measure: Addictives and psychiatric comorbidity
timeFrame: 1 day
Other outcomes:
Locations:
city: CHU Nantes
country: France
facility: Prétagut
Study officials:
affiliation: Nantes University Hospital
name: Stephane Pretagut
role: PRINCIPAL_INVESTIGATOR
affiliation: University Hospital, Bordeaux
name: Serge Lise
role: PRINCIPAL_INVESTIGATOR
affiliation: University Hospital, Grenoble
name: Michel GUINOT
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02158000: Aspiration of Excessive Endometrial Fluid at the Day of Ovum Retrieval Plus Diosmin in (ICSI) Cycles
Official title: Aspiration of Excessive Endometrial Fluid at the Day of Ovum Retrieval Plus Diosmin in (ICSI) Cycles
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Infertility
Lead sponsor: Benha University
Sponsor class: OTHER
First posted: 2014-06-06
Enrollment: 200
Sex: FEMALE
Minimum age (years): 23
Maximum age (years): 48
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: To notify the effect of aspiration of excessive endometrial fluid in addition to Diosmin in cases undergoing intracytoplasmic sperm injection (ICSI) cycles.

Detailed description: Objectives: To notify the effect of aspiration of excessive endometrial fluid in addition to Diosmin in cases undergoing intracytoplasmic sperm injection (ICSI) cycles.

Study design: Prospective randomized controlled clinical trial.

Patients and Methods: 200 women with excessive endometrial fluid by transvaginal ultrasound during ICSI cycles are randomly scheduled into two equal groups. In group A, one tab every 8 hs Diosmin ( 500mg) beginning from the day of ovum retrieval in addition to aspiration of the fluid by an IUI catheter ; while in group B (control group), no thing is given or done. The main outcome measures are presence of the fluid on the day of embryo transfer and the pregnancy rate on those patients.

Eligibility criteria: Inclusion Criteria:

* women with excessive endometrial fluid by transvaginal ultrasound during ICSI cycles

Exclusion Criteria:

* none

Primary outcomes:
measure: the pregnancy rate
timeFrame: is checked 16 days after embryos transfer
Secondary outcomes:
measure: presence of the fluid on the day of embryo transfer
timeFrame: at the day of embryo transfer
Other outcomes:
Locations:
city: Banhā
country: Egypt
facility: Benha univesity hospital
state: El Qualyobia
Study officials:
affiliation: Department of Obstetrics and Gynecology, Benha University Hospital
name: khalid mohamed
role: STUDY_CHAIR
References:
Clinical trial NCT02679300: Virtual Reality and Pain Perception During Exercises for Patients With Chronic Non-specific Low Back Pain
Official title: The Influence of a Virtual Reality Environment on Pain Perception During Exercises for Patients With Chronic Non-specific Low Back Pain: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Low Back Pain
Keywords: Chronic Low Back Pain
Virtual Reality
Serious Gaming
Exercise Therapy
Distraction
Lead sponsor: Hasselt University
Sponsor class: OTHER
Collaborators: name: Jessa Hospital
First posted: 2016-02-10
Enrollment: 84
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Immersion in a virtual reality environment has been shown to reduce pain during a variety of painful medical procedures, such as wound care for burn patients and dental care. Often, serious games are used to distract patients from this painful procedures. Recently, serious games have also been developed for patients with low back pain. Because patients with low back pain frequently experience pain during exercises, the investigators hypothesize that exercising with serious games can reduce the pain intensity and the time spent thinking of pain during exercises. To test this hypothesis, the investigators will conduct a randomized controlled trial where two groups will be compared: the experimental group will perform one session of exercises with serious games, while the control group will perform one session of the same exercises without the serious games.


Eligibility criteria: Inclusion Criteria:

* Chronic non-specific low back pain, with or without referred pain to the legs
* Age 18-65
* Able to understand Dutch
* A minimum pain intensity of 3/10 on the numeric pain rating scale at the time of the test
* Being familiar with pelvic tilt exercises

Exclusion Criteria:

* Spinal surgery in the past
* Pregnancy
* Serious underlying pathologies (e.g. multiple sclerosis, tumors,...)
* Signs or symptoms of nerve root involvement
* Known skin-allergy for tape

Primary outcomes:
measure: Average pain intensity during exercises using the numeric pain rating scale
timeFrame: Day 1
measure: Time spent thinking of the pain using a numeric rating scale
timeFrame: Day 1
Secondary outcomes:
measure: Pain intensity after the exercises using a numeric rating scale
timeFrame: Day 1
measure: Harmfulness of the exercises using a numeric rating scale
timeFrame: Day 1
Other outcomes:
measure: Number of pelvic tilts
timeFrame: Day 1
measure: Immersion (questionnaire will be used to measure the level of immersion)
timeFrame: Day 1
Locations:
city: Hasselt
country: Belgium
facility: Hasselt University
Study officials:
References:
citation: Matheve T, Bogaerts K, Timmermans A. Virtual reality distraction induces hypoalgesia in patients with chronic low back pain: a randomized controlled trial. J Neuroeng Rehabil. 2020 Apr 22;17(1):55. doi: 10.1186/s12984-020-00688-0.
Clinical trial NCT03868800: Shared Decision-Making and Dialysis Choice
Official title: Shared Decision-Making and Dialysis Choice: A Complex Intervention
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Kidney Diseases
Lead sponsor: University of Aarhus
Sponsor class: OTHER
Collaborators: name: Aarhus University Hospital
name: Hillerod Hospital, Denmark
name: Hospital of Southern Jutland
name: Regional Hospital Holstebro
First posted: 2019-03-11
Enrollment: 402
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: The SDM-DC intervention is designed for patients with kidney failure who must make a decision regarding type of dialysis: haemodialysis or peritoneal dialysis. SDM-DC consists of patient and his or her relative(s) being given a patient decision aid called 'Dialysis choice' and booked for meetings with a dialysis coordinator.

Detailed description: The dialysis coordinators were trained in the why, what and how in relation to SDM-DC and to deliver the intervention by tailoring to patients' needs and using three different communication skills: mirroring, active listening and value clarification. The patient decision aid was designed to be utilised during and between the SDM-DC meetings. The patient decision aid is in paper format and consists of a set of tools: a decision map, an overview of uremic symptoms, an overview of options, and the Ottawa Personal Decision Guide. More specifically, the patient decision aid makes explicit the dialysis decision, describes options, benefits and harms using the best available evidence, and intends to help patients clarify their values by indicating the importance of the benefits and harms out of scale from (0) to (5). Four videos with personal stories were available to be shown and discussed at the meetings if the patient preferred to see the reason why another patient has chosen a specific option. Each video showed one option with a patient telling why he/she chose that option, and how he/she weighed the advantages and disadvantages.

Eligibility criteria: Inclusion Criteria:

* Estimated glomerular filtration rate below 20 ml/min
* A clinical judgement made by the contact nurse and the contact physician

Exclusion Criteria:

* Conservative care
* A set date for a transplantation with a living donor
* Not able to participate due to cognitive impairment

Primary outcomes:
measure: Patients experiences of a shared decision-making process
timeFrame: 14 days after interventions
measure: Knowledge, readiness for decision-making and decision quality
timeFrame: 14 days after interventions
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Aarhus University Hospital
name: Jeanette Finderup, Master
role: PRINCIPAL_INVESTIGATOR
References:
citation: Finderup J, Lomborg K, Jensen JD, Stacey D. Choice of dialysis modality: patients' experiences and quality of decision after shared decision-making. BMC Nephrol. 2020 Aug 5;21(1):330. doi: 10.1186/s12882-020-01956-w.
Clinical trial NCT03793400: Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor
Official title: Long-term Outcome of Punctate Inner Choroidopathy or Multifocal Choroiditis With Active Choroidal Neovascularization Managed With Anti-vascular Endothelial Growth Factor
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Choroidal Neovascularization
Punctate Inner Choroidopathy
Keywords: punctate inner choroidopathy
multifocal choroidits
choroidal neovascularization
anti-VEGF
long-term outcome
Lead sponsor: Changhua Christian Hospital
Sponsor class: OTHER
First posted: 2019-01-04
Enrollment: 22
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The investigators included punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization patients with follow up over 4 years.

Brief summary: To evaluate the long-term outcome of active choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) after anti-vascular endothelial factor treatment.

Detailed description: To evaluate the long-term outcome of active choroidal neovascularization (CNV) in punctate inner choroidopathy (PIC) or multifocal choroiditis (MFC) after anti-vascular endothelial factor treatment.

The age, sex, best corrected visual acuity (BCVA) in Snellen chart, and refractive status for each patient were recorded. All patients had thorough clinical examinations, including slit lamp biomicroscopy, indirect ophthalmoloscopy, and spectral domain optical coherence tomography during each visit. Fundus photography, fluorescein angiography, and indocyanine angiography were performed on all patients. OCT angiography was performed.

Eligibility criteria: Inclusion Criteria:

1. Patients were punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization.
2. Follow up over 4 years.

Exclusion Criteria:

1. Patients were not punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization
2. Patients were punctate inner choroidopathy or multifocal choroiditis with active choroidal neovascularization but loss follow over 1 year.

Primary outcomes:
measure: Wilcoxon Signed-Rank test
timeFrame: Baseline,48 month.
Secondary outcomes:
measure: visual acuity
timeFrame: Baseline,48 month.
Other outcomes:
Locations:
city: Changhua
country: Taiwan
facility: Changhua Christian Hospital
Study officials:
References:
Clinical trial NCT00271700: Improving Glycemic Control on GMS: A Quality Improvement Study
Official title: Improving Glycemic Control on GMS: A Quality Improvement Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Diabetes Mellitus
Keywords: Diabetes Mellitus
Outcome Assessment (Healthcare)
Inpatients
Hospital Information Systems
Education
Lead sponsor: Brigham and Women's Hospital
Sponsor class: OTHER
Collaborators: name: Novo Nordisk A/S
First posted: 2006-01-04
Enrollment: 179
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will examine whether new processes and technologies for monitoring diabetic patients' insulin levels improves patient care at Brigham and Women's Hospital.

Detailed description: This study will examine whether new processed and technologies for monitoring diabetic patients' insulin levels improves patient care. Patients at Brigham and Women's Hospital (BWH), staying on the General Medicine Service, who have Type 2 diabetes and who are not on IV insulin can participate in this study. Physicians and nurses will be taught new rules to care for diabetic patients, while in the hospital. Also, the BWH computer system will be updated to include these new rules for administering insulin. Patients who participate in the study will be randomly placed into one of two groups: one group that will be cared for by physicians and nurses who have learned these new rules for administering insulin; or the second group, who will receive diabetes care at BWH before the new rules were adopted. The study will last approximately 1 year.

Eligibility criteria: Inclusion Criteria:

* Subjects will include all type 2 diabetic patients on the General Medicine Service (GMS) of Brigham and Women's Hospital (BWH) who do not have an indication for IV insulin.

Exclusion Criteria:

* Type 2 diabetic patients on the General Medicine Service (GMS) of Brigham and Women's Hospital (BWH) who have an indication for IV insulin.

Primary outcomes:
measure: - Point-of-care testing glucose values (percent of routine glucose readings between 60 and 180 mg/dL)
measure: - Lab glucose values (percent of routine glucose readings between 60 and 180 mg/dL)
Secondary outcomes:
measure: - Quality of insulin orders using explicit criteria
Other outcomes:
Locations:
city: Boston
country: United States
facility: Brigham and Women's Hospital
state: Massachusetts
Study officials:
affiliation: Brigham and Women's Hospital
name: Jeffrey L Schnipper, MD, MPH
role: PRINCIPAL_INVESTIGATOR
References: