Clinical trial NCT03807024: Age-specific Prevalence and Comparisons of UDS and Bladder Diary Between OAB-wet and -Dry Women
Official title: Age-specific Prevalence and Comparisons of Urodynamics and Bladder Diary Between Overactive Bladder-wet and -Dry Women Based on Bladder Diary
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Urinary Bladder, Overactive
Keywords: Overactive bladder
Bladder diary
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
First posted: 2019-01-16
Enrollment: 1071
Sex: FEMALE
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Between July 2009 and January 2018, all women older than 20-year-old with OAB visiting a medical center for evaluation were enrolled.

Brief summary: The knowledge of the age-specific prevalence of overactive bladder syndrome (OAB)-wet and -dry women is important for understanding the impact of aging on OAB. Thus, our aim is to describe clinically differences between OAB-wet and -dry women.

Detailed description: Between July 2009 and January 2018, all women with OAB visiting a medical center for evaluation were reviewed. The classification of OAB-wet or OAB-dry is based on the record of the three-day bladder diary of each patient. The diagnosis of OAB in each patient was based on the presence of at least one episode of urgency in her three-day bladder diary and with the absence of stress urinary incontinence. The presence of at least one episode of urgency associated incontinence was defined to be OAB-wet, otherwise, OAB-dry.

Eligibility criteria: Inclusion Criteria:

1. More than 20-year-old
2. Female
3. Diagnosed with overactive bladder by bladder diary

Exclusion Criteria:

1. Younger than 20-year-old
2. Pregnant or planned to be pregnant

Primary outcomes:
measure: Diagnosis of OAB
timeFrame: Between July 2009 and January 2018
Secondary outcomes:
measure: Age-specific comparison
timeFrame: Between July 2009 and January 2018
Other outcomes:
Locations:
Study officials:
affiliation: National Taiwan University Hospital
name: Ho-Hsiung Lin, PhD
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Coyne KS, Sexton CC, Bell JA, Thompson CL, Dmochowski R, Bavendam T, Chen CI, Quentin Clemens J. The prevalence of lower urinary tract symptoms (LUTS) and overactive bladder (OAB) by racial/ethnic group and age: results from OAB-POLL. Neurourol Urodyn. 2013 Mar;32(3):230-7. doi: 10.1002/nau.22295. Epub 2012 Jul 27.