Clinical trial NCT06754475: Effects of Upper Extremity Low Volume HIIT in Heart Failure
Official title: The Effect of Upper Extremity Low-Volume High-Intensity Interval Training on Physical and Cognitive Functions in Heart Failure Patients
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: High Intensity Interval Training
Heart Failure
Exercises
Keywords: high intensity interval training
upper extremity
exercises capacity
Lead sponsor: Tarsus University
Sponsor class: OTHER
First posted: 2024-12-31
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomised controlled trial
Primary purpose: TREATMENT

Brief summary: This study was planned to investigate the effects of upper extremity low-volume high-intensity interval training (LV-HIIT) on physical and cognitive function in patients with heart failure with preserved ejection fraction(HFpEF).The research was planned as a randomized controlled trial. Patients with clinically stable HFpEF at cardiology clinic will be included in the study. These cases will be randomly divided into two groups: intervention group and control grup. After 8 weeks intervention physical functions before and after treatment; functional exercise capacity, arm exercise capacities , peripheral muscle strength , fatigue cognitive functions; anxiety and depression and fear of movement will be evaluated.

Detailed description: Patients in the DV-HIIT group will receive training consisting of 4 minutes of warm-up and cool-down at 50% Wmax on an arm ergometer, 1 minute of training at 85-95% Wmax work intensity, followed by 6 interval training periods including 1 minute of active recovery periods at 50-70% Wmax, 2 days/week, totaling 8 weeks of training. The control group will be followed with standard medical treatment.

Eligibility criteria: Inclusion Criteria:

* Clinical condition stable for ≥4 weeks.
* New York Heart Association functional classification I-II to III
* Over 18 years old

Exclusion Criteria:

History of CABG surgery

* Unstable angina pectoris
* Severe arrhythmia
* Acute pericarditis, endocarditis, myocarditis
* Severe left ventricular failure (EF \<40%)
* Acute pulmonary embolism
* History of syncope
* Dissecting aneurysm
* Thrombophlebitis
* Orthopedic disorders that may interfere with exercise
* Uncontrolled hypertension, severe pulmonary arterial hypertension
* Moderate-severe valve disease
* Decompensated Congestive Heart Failure
* Electrolyte abnormalities
* Hypertrophic Cardiomyopathy

Primary outcomes:
measure: maximal arm exercises capacity
timeFrame: At baseline and after 8 week
measure: Functional capacity
timeFrame: At baseline and after 8 week
measure: Upper extremity muscle strength
timeFrame: At baseline and after 8 week
measure: reaction time
timeFrame: At baseline and after 8 week
measure: cognitive function
timeFrame: At baseline and after 8 week
measure: Postural sway
timeFrame: At baseline and after 8 week
measure: heart rate variablity
timeFrame: At baseline and after 8 week
Secondary outcomes:
measure: hand steadness
timeFrame: At baseline and after 8 week
measure: Anxiety and depresion
timeFrame: At baseline and after 8 week
measure: activities of daily living
timeFrame: At baseline and after 8 week
Other outcomes:
Locations:
city: Mersin
country: Turkey
facility: Tarsus University, TARSUS, Mersin
state: Mersi̇n
city: Yeni̇şehi̇r
country: Turkey
facility: Nurel Ertürk, TARSUS, Mersin
state: Mersi̇n
Study officials:
References: