Clinical trial NCT04741958: Role of Ultrasound Guided Peripheral Thoracic Tumors
Official title: Role of Ultrasound Guided Percutaneous Transthoracic Core Needle Biopsy in Diagnosis of Peripheral Thoracic Tumors
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Thoracic Neoplasms
Keywords: Ultrasound; .
Chest; Diseases
Core needle biopsy
Lead sponsor: Beni-Suef University
Sponsor class: OTHER
First posted: 2021-02-05
Enrollment: 60
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: The current study is a case series study conducted on 60 patients that had radiographic evidence of thoracic mass suspected of malignancy
Primary purpose: DIAGNOSTIC

Brief summary: The aim of the study was to calculate sensitivity, and accuracy of ultrasound guided percutaneous core needle biopsy in different thoracic tumors (lung, pleural, chest wall and mediastinal).

Detailed description: Peripheral intrathoracic shadows are common presentation of different diseases of different origin (chest wall, pleura, pulmonary, and mediastinum), they are increasing in numbers including, peripheral lung cancer, tuberculosis, pneumonia, and atelectasis. \[1\] Thoracic masses with wall contact represent a frequent pathology that requires complex imaging studies, and often interventional procedures, in order to reach the complete diagnosis. In most cases, after a thoracic lesion is found on a thoracic X-Ray, the next step is to perform a CT and/or a bronchoscopy exam, but pleural and pulmonary lesions often call for additional investigations.

Therefore, transthoracic ultrasonography (US) permits visualization of these lesions, their structural characterization, while offering suggestive elements for their malignant nature and for the differential diagnosis.

Sonography has the capacity to clarify the nature of opaque lesions such as effusions, atelectasis, masses, and consolidations. Transthoracic ultrasound has received increased interest from chest Physicians in recent years as it has the advantages of bedside availability, absence of radiation, and guided aspiration of fluid-filled areas and solid tumors.

Furthermore US allows percutaneous guided biopsies with lower risks compared with the radiological guiding methods (fluoroscopy and CT). Trransthoracic US can replace other imaging modalities of the chest and guide a variety of diagnostic and therapeutic procedures. Under real time US guidance, the success rate of transthoracic needle aspiration or biopsy (TNB) significantly increases, whereas the risk of complications is greatly reduced.

Eligibility criteria: Inclusion Criteria:

1. An acoustic window for the ultrasound beam to penetrate.
2. Patients have platelet count more than 100000 and normal prothrombin time.

Exclusion Criteria:

1. Cardio vascular instability.
2. Arterio venous malformation or aneurysm.
3. Patients with uncontrolled convulsions

Primary outcomes:
measure: Value of sonar guided true cut needle biopsy in diagnosis in different thoracic tumors (lung, pleural, chest wall and mediastinal).
timeFrame: 8week
Secondary outcomes:
Other outcomes:
Locations:
city: Banī Suwayf
country: Egypt
facility: Benisuef Unversity
Study officials:
affiliation: beni seuf unversity
name: maha fathy, MD of chest
role: PRINCIPAL_INVESTIGATOR
References:
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