Clinical trial NCT05742958: The Quality of Recovery After Intrathecal Morphine or Adductor Canal Block in Anterior Cruciate Ligament Reconstruction
Official title: The Quality of Recovery After Intrathecal Morphine or Adductor Canal Block Added to Spinal Anesthesia in Patients Undergoing Arthroscopic Anterior Cruciate Ligament Reconstruction
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE4
Conditions: Adductor Canal Block
Intrathecal Morphine
Arthroscopic Anterior Cruciate Ligament Reconstruction
Quality of Recovery
Keywords: intrathecal morphine
adductor canal block
quality of recovery
Lead sponsor: Cukurova University
Sponsor class: OTHER
First posted: 2023-02-24
Enrollment: 70
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The Quality of Recovery 40 (QoR-40) is a multidimensional questionnaire that addresses many aspects of postoperative recovery. The QoR-40 has been used many times to measure the recovery of patients after different surgeries, and this questionnaire seems to be a reliable tool for evaluating anesthesia-related techniques, including regional anesthesia. Arthroscopic knee surgery causes moderate to severe postoperative pain for most patients. Various methods such as different systemic drugs, peripheral or central blocks and intra-articular injections have been developed for the effective, safe and long-term control of this pain. In recent years, it has been shown that regional anesthesia techniques reduce the need for opioids in orthopedic ambulatory surgeries and accelerate recovery and discharge. However, there is no consensus on which is the best approach among these various regional techniques. However, adductor canal block (ACB) and intrathecal morphine (ITM) are the preferred regional methods in the perioperative pain management of knee surgery. In this study, it was aimed to test the effectiveness of intrathecal morphine or adductor canal block added to spinal anesthesia on the quality of recovery in patients undergoing arthroscopic anterior cruciate ligament reconstruction surgery.


Eligibility criteria: Inclusion Criteria:

* American Society of Anesthesiologists (ASA) physical status I or II adult patients aged 18-65 years undergoing elective arthroscopic anterior cruciate ligament reconstruction will be included in the study.

Exclusion Criteria:

* We will exclude patients with known coagulopathy, allergies to the studied drugs, obesity (BMI \>35kg/m2), renal and/or hepatic insufficiency, chronic pain syndrome, mental impairment, depression, chronic alcoholism, and usage of antidepressant and analgesic drugs before surgery.

Primary outcomes:
measure: 24-hour Quality of Recovery-40 (QoR-40) questionnaire scores
timeFrame: Postoperative 24-hour.
Secondary outcomes:
measure: Numeric Rating Score (NRS)
timeFrame: Postoperative 1, 2, 4, 8, 12 and 24-hour.
measure: Supplement analgesia requirement
timeFrame: Postoperative 1, 2, 4, 8, 12 and 24-hour.
measure: The time to first postoperative mobilisation
timeFrame: Duration of postoperative 24-hour
measure: Discharge time
timeFrame: Duration of postoperative 24-hour
measure: Treatment satisfaction
timeFrame: Postoperative 24-hour
Other outcomes:
Locations:
city: Adana
country: Turkey
facility: Cukurova University
state: Saricam
Study officials:
References: