Clinical trial NCT05663541: Validity and Reliability of Lower Extremity Position Test in Patients with Multiple Sclerosis
Official title: Validity and Reliability of Lower Extremity Position Test in Patients with Multiple Sclerosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Multiple Sclerosis
Sensory Impairments
Proprioceptive Disorders
Validity
Reliability
Lead sponsor: Pamukkale University
Sponsor class: OTHER
First posted: 2022-12-23
Enrollment: 90
Sex: ALL
Minimum age (years): 20
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Multiple sclerosis indivuduals

Brief summary: Sensory disorders are one of the most important problems in individuals with MS, and these disorders are among the first symptoms of MS. Loss of sense of proprioception is particularly common in patients with MS. Studies show that assessment methods for the quantitative measurement of sensory disorders are lacking. Especially in the clinic, there is no evaluation method that evaluates the sense of proprioception. Therefore, the aim of this study perform the validity and reliability study of the lower extremity position test to evaluate proprioception sense in individuals with MS.


Eligibility criteria: Inclusion Criteria:

* 20-65 years old
* EDSS score between 0-5
* Person who has not had an attack in the last 1 month or who is not in the attack period
* Person without systemic disease such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy
* Person who has not undergone surgery that restricts balance function in the lower extremity.
* Person without hip, knee and ankle contracture
* Person who does not have additional neurological disease
* Person who does not use vestibulosupressants or drugs that may cause neuropathy and does not have a history of alcohol use
* To have full cooperation and adaptation to the work
* Individuals who agree to receive treatment will be included in the study.

Exclusion Criteria:

* Being younger than 20 years old and over 65 years old
* Being in the attack period
* Hip, knee or ankle contracture
* Being greater than EDSS 5
* Having systemic diseases such as hypertension, heart disease, Diabetes Mellitus, hyperlipidemia, malignancy
* Having an additional neurological disease
* Having a vestibulospressant or drug or alcohol use habit that causes neuropathy
* Not cooperating and adapting to the work

Primary outcomes:
measure: Sensorial Assessment-1
timeFrame: through study completion, an average of 1 year
measure: Sensorial Assessment-2
timeFrame: through study completion, an average of 1 year
measure: Balance Assessment-1
timeFrame: through study completion, an average of 1 year
measure: Balance Assessment-2
timeFrame: through study completion, an average of 1 year
measure: Walking Speed Assessment
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
measure: Demographic Assessment
timeFrame: through study completion, an average of 1 year
measure: Expanded Disability Status Scale (EDSS)
timeFrame: through study completion, an average of 1 year
Other outcomes:
Locations:
city: Bursa
country: Turkey
facility: Romatem Bursa Fizik Tedavi ve Rehabilitasyon Hastanesi
Study officials:
References: