Clinical trial NCT05173649: Calisthenic and Neuromuscular Training in Patients With Knee OA.
Official title: Effect of Calisthenics and Neuromuscular Training in Patients With Knee Osteoarthritis.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Calisthenic training
Neuromuscular training
Knee Osteoarthritis
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-12-30
Enrollment: 36
Sex: ALL
Minimum age (years): 40
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study is to compare effects of calisthenics and neuromuscular training in patients with knee osteoarthritis.

Detailed description: OsteoArthristis (OA) is the most frequent form of arthritis and a leading cause of pain and disability worldwide. OA can affect any synovial joint, although the hip, knee, hand, foot and spine are the most commonly affected sites.

The knee is the most commonly affected joint and knee OA (KOA) represents the leading joint disorder in the world. At present, there is no preventive or curative drug treatment available for KOA.

Physical therapy plays a significant role in treating patients with knee OA. Rehabilitation enables the patient to cope with their daily task independently and mainly focus on self-help and patient-driven treatments rather than on passive therapies delivered by clinicians.

A systemic review was conducted on Comparative Effect of Calisthenics and Proprioceptive Exercises on Pain, Proprioception, Balance and Function in Chronic Osteoarthritis of Knee. According to this study Light intensity Calisthenics exercises are effective and can be recommended as an adjunct to conventional physiotherapy for the patients with Osteoarthritis knee.

Another research was conducted on Efficacy of Neuromuscular Training on Pain, Balance and Function in Patients with Grade I and II Knee Osteoarthritis. The results shows that although conventional exercise program is effective in reducing knee pain, and increasing lower extremity muscle strength and range of motion, adding neuromuscular training (KBA) along with conventional exercise program in rehabilitation leads to higher improvement on balance and function in patient with knee grade I and II osteoarthritis.

A positive effect has been observed in treating patients with both the interventions.

The past research records are evident that therapists have determined individual effects of calisthenics and neuromuscular training for rehabilitation of Knee OA. The evidence for implementation of two protocols for rehabilitation of Knee OA is sparse. So the aim of the study is to compare effects of calisthenics and neuromuscular training in patients with knee osteoarthritis.

Eligibility criteria: Inclusion Criteria:

1. Subjects with chronic OA (symptoms for more than 3 months).
2. Subjects willing to participate and take treatment.
3. Grade of 2 to 3 as per Kellegren and Lawrence radiographic classification.

Exclusion Criteria:

1. Subjects having any systemic joint pathologies, inflammatory joint disease (e.g.

   Rheumatoid arthritis, gouty arthritis, psoriatic arthritis).
2. Subjects who had any neurological deficit (paresthesia, sensory loss, radiculopathy, myelopathy any mental illness (Dementia, Alzheimer's, Parkinson disease etc.) that can affect orientation and concentration.
3. Subjects on medication like antidepressants, corticosteroid, and anti-inflammatory medications.
4. Peripheral vascular diseases.
5. Any history of surgery related to lower extremity.
6. Subjects having metal implants in the lower limb

Primary outcomes:
measure: WOMAC(Western Ontario and McMaster Universities Osteoarthritis Index)
timeFrame: 6 weeks
measure: NPRS(Numeric pain rating scale)
timeFrame: 6 weeks
measure: Short Physical Performance Battery
timeFrame: 6 weeks
measure: Mini BES-Test
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Riphah International University
state: Punjab
Study officials:
affiliation: Riphah International University
name: Aruba Saeed, PhD*
role: STUDY_CHAIR
References: