Clinical trial NCT06964841: PRIMARY TESTICULAR LYMPHOMA
Official title: PRIMARY TESTICULAR LYMPHOMA WITH EXTRA-NODAL STOMACH AFFECTATION
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Testicular Lymphoma
Keywords: testis
lymphoma
nodal
stomach
Lead sponsor: Instituto Mexicano del Seguro Social
Sponsor class: OTHER_GOV
First posted: 2025-05-09
Enrollment: 1
Sex: MALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 57 year old male with testicular lymphoma

Brief summary: 742 / 5.000 A 57-year-old male: Denies chronic degenerative, allergic, traumatic, transfusional, or surgical complications. He denies a family history of testicular cancer or abnormalities in testicular descent.

The patient presented with an enlarged right testicle that had been present for 1 month. He saw his family doctor, who prescribed antibiotic and analgesic treatment, without improvement, and was referred to our service. Upon examination, the right testicle was palpable, nontender, slightly enlarged, indurated, with nodulations measuring 0.5 cm in diameter, and free spermatozoa.

The left testicle was normal.

He underwent radical orchiectomy, which revealed renal testicular lymphoma.

Detailed description: A 57-year-old male: Denies chronic degenerative, allergic, traumatic, transfusional, or surgical complications. He denies a family history of testicular cancer or abnormalities in testicular descent.

The patient presented with an enlarged right testicle that had been present for 1 month. He saw his family doctor, who prescribed antibiotic and analgesic treatment, without improvement, and was referred to our service. Upon examination, the right testicle was palpable, non-tender, slightly enlarged, indurated, with nodulations measuring 0.5 cm in diameter, and free spermatozoa.

The left testicle was normal.

He underwent radical orchiectomy, which revealed renal-testicular lymphoma.

On the first postoperative day, the patient began to have stools with malignant cells and discontinuous invasion of the umbilical cord.

He was evaluated by the Gastroenterology department, who indicated the performance of an endoscopy, which revealed a 6 cm bleeding gastric ulcer. A biopsy was taken and a diffuse B-cell lymphoma was detected.

He was evaluated by the Gastroenterology department, who indicated the performance of an endoscopy, which revealed a large lesion.

On the first postoperative day, the patient began to have stools with malignant cells and discontinuous invasion of the umbilical cord.

He was evaluated by the Gastroenterology department, who indicated the performance of an endoscopy, which revealed a large lesion.

The patient continued to have melena and grade IV anemia. He was referred to pathology, where he was found to have OMS. He showed no improvement despite blood transfusions. He died. Immunohistochemistry for both testicular lesions and on the third postoperative day.

Eligibility criteria: Inclusion Criteria:

* Patient with testicular lymphoma

Exclusion Criteria:

* Patient without testicular lymphoma

Primary outcomes:
measure: Mortality
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Mérida
country: Mexico
facility: Instituto Mexicano del Seguro Social
state: Yucatán
Study officials:
References:
citation: Motyckova M, Vosahlova V, Belada D, Simkovic M, Zak P. [Primary testicular lymphoma]. Vnitr Lek. 2017 Summer;63(6):415-422. Czech.