Clinical trial NCT06808659: Effects of Neural Mobilization and Stretching in Piriformis Syndrome
Official title: Comparative Effects of Neural Mobilization of Sciatic Nerve Versus Stretching Among Patients With Piriformis Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Piriformis Syndrome
Keywords: Physiotherapy
Piriformis Stretching
Visual Analog Scale (VAS)
Pain Management
FAIR Test
Range of Motion
Lead sponsor: Bahria University
Sponsor class: OTHER
First posted: 2025-02-05
Enrollment: 40
Sex: ALL
Minimum age (years): 22
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: In a study involving 40 patients diagnosed with sciatica, researchers aimed to investigate whether neural mobilization of the sciatic nerve or stretching of the piriformis muscle was more effective in treating piriformis syndrome. The patients were divided into two groups, each containing 20 individuals. Group A underwent neural mobilization therapy, while Group B performed piriformis muscle stretches, with both groups receiving treatment three times a week for two weeks. Assessments, including Visual Analog Scale (VAS) for pain, hip range of motion (ROM) in flexion, abduction, and external rotation, as well as the FAIR test, were conducted before and after the interventions.
Primary purpose: TREATMENT

Brief summary: This study compares the effects of piriformis stretching and neural mobilization of the sciatic nerve in individuals with piriformis syndrome, a condition that is frequently characterized by hip and buttock pain and discomfort brought on by the piriformis muscle compressing the sciatic nerve.

Detailed description: In a study involving 40 patients diagnosed with sciatica, researchers aimed to investigate whether neural mobilization of the sciatic nerve or stretching of the piriformis muscle was more effective in treating piriformis syndrome. The patients were divided into two groups, each containing 20 individuals. Group A underwent neural mobilization therapy, while Group B performed piriformis muscle stretches, with both groups receiving treatment three times a week for two weeks. Assessments, including Visual Analog Scale (VAS) for pain, hip range of motion (ROM) in flexion, abduction, and external rotation, as well as the FAIR test, were conducted before and after the interventions.

Eligibility criteria: Inclusion Criteria:

* Positive lasegue sign
* Positive piriformis sign
* Tenderness at sciatic notch (over piriformis muscle).

Exclusion Criteria:

* • Prior surgery of lumbar spine (laminectomy)

  * Unrecognized pelvic fracture
  * Known case of renal stones
  * Disc herniation in lumbar spine
  * Myositis ossificans of piriformis muscle.

Primary outcomes:
measure: Pain Reduction
timeFrame: 2 weeks
measure: Increase Range of Motion
timeFrame: 2 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: Isra Institute of Rehabilitation Sciences
state: Sindh
Study officials:
name: Rabia Khan, Masters of Science
role: PRINCIPAL_INVESTIGATOR
References:
citation: Othman IK, Raj NB, Siew Kuan C, Sidek S, Wong LS, Djearamane S, Loganathan A, Selvaraj S. Association of Piriformis Thickness, Hip Muscle Strength, and Low Back Pain Patients with and without Piriformis Syndrome in Malaysia. Life (Basel). 2023 May 18;13(5):1208. doi: 10.3390/life13051208.
citation: Hu YE, Ho GWK, Tortland PD. Deep Gluteal Syndrome: A Pain in the Buttock. Curr Sports Med Rep. 2021 Jun 1;20(6):279-285. doi: 10.1249/JSR.0000000000000848.
citation: Danazumi MS, Yakasai AM, Ibrahim AA, Shehu UT, Ibrahim SU. Effect of integrated neuromuscular inhibition technique compared with positional release technique in the management of piriformis syndrome. J Osteopath Med. 2021 May 31;121(8):693-703. doi: 10.1515/jom-2020-0327.
citation: Burke CJ, Walter WR, Adler RS. Targeted Ultrasound-Guided Perineural Hydrodissection of the Sciatic Nerve for the Treatment of Piriformis Syndrome. Ultrasound Q. 2019 Jun;35(2):125-129. doi: 10.1097/RUQ.0000000000000360.
citation: Shahzad M, Rafique N, Shakil-Ur-Rehman S, Ali Hussain S. Effects of ELDOA and post-facilitation stretching technique on pain and functional performance in patients with piriformis syndrome: A randomized controlled trial. J Back Musculoskelet Rehabil. 2020;33(6):983-988. doi: 10.3233/BMR-181290.
citation: Ahmad Siraj S, Dadgal R. Physiotherapy for Piriformis Syndrome Using Sciatic Nerve Mobilization and Piriformis Release. Cureus. 2022 Dec 26;14(12):e32952. doi: 10.7759/cureus.32952. eCollection 2022 Dec.
citation: Ankar P, Ratnani GR, Ramteke SU, Jaiswal PR. Effect of Neuromuscular Training and Neurodynamic Solutions for Asymptomatic Prolapsed Intervertebral Disc and Coexisting Piriformis Syndrome in a 19-Year-Old: A Comprehensive Case Report. Cureus. 2024 Jan 27;16(1):e53050. doi: 10.7759/cureus.53050. eCollection 2024 Jan.