Clinical trial NCT03811041: Adolescent Depression Associated With Parental Depression
Official title: Adolescent Depression Associated With Parental Depression : Screening, Prevalence and Secondary Prevention From the Meeting of Depressed Parents on Primary Care
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Depression
Lead sponsor: University Hospital, Brest
Sponsor class: OTHER
First posted: 2019-01-22
Enrollment: 80
Sex: ALL
Minimum age (years): 11
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: DIAGNOSTIC

Brief summary: Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care.

In children the existence of a parental depression is a significant and recognized risk factor for the development of a depression. It is regularly reported that 30% of adolescents of depressed parents have depression themselves. General Practitioners (GP) have significant access to the depression of adults, potentially parents of teenagers. In fact, 20% of patients in the regular active file of one GP have depression. The primary health care system could provide indirect but voluminous and unprecedented access to the identification of adolescent depression at an early stage from the encounter of depressed parents.

The difficulties of articulation between primary care (PC) and mental health devices are demonstrated. They disrupt the care pathways of adolescents detected in PC, prevention, and may even disturb early detection of depression. An organized joint between the PC and a specialized mental health service for adolescents ("Maison Des Adolescents" MDA) could promote the process of screening and preventing depression of adolescents of depressed parents encountered in PC.

In addition, if the effects of parental depression on adolescents are established, they remain complex and interactive. They vary by age and sex of the child but also the sex of the parent. A concomitant study of adolescent and parent depression will provide data to analyze the prevalence of depressed parent adolescent depression and to define risk or protection factors.

AdoDesP study is a cluster randomised trial (randomisation of the GPs) which compare a group of adolescent with PC articulated with mental health service (MDA) and an other group without articulation (routine cares).

A third group of depressed adolescents will be constituted to analyse parental depression of depressed adolescents.


Eligibility criteria: Inclusion Criteria:

* Parents of groups 1 and 2 :

  * Major patient consulting his GP
  * Depressed patient
  * Parent of adolescent aged between 11 and 18 years old
* Adolescents of groups 1 and 2 :

  * Aged more than 11 and less than 18 years old
  * Parent included in the study
* Parents of group 3 :

  * Parent of depressed adolescent under care at the MDA of Marseille, included in the study and whose depression is confirmed by HSCL25 scale
* Adolescents of group 3 :

  * Aged more than 11 and less than 18 years old
  * Depressed patient
  * Under care at the MDA of Marseille since less than 1 month

Exclusion Criteria:

* Parents of groups 1, 2 and 3 :

  * Minor patient
  * Enable to give his consent
  * Patient with guardianship or curatorship
  * Non consenting patient
  * Pregnant or nursing mother
* Adolescents of groups 1 and 2 :

  * Aged \< 11 or ≥18
  * Parent whose depression isn't confirmed by HSCL25 scale
  * Non consenting adolescent
  * Pregnant or nursing mother
* Adolescent of group 3 :

  * Aged \< 11 or ≥18
  * Non depressed adolescent
  * Non consenting patient
  * Pregnant or nursing mother

Primary outcomes:
measure: Changes in adolescents' depression intensity
timeFrame: Day 0 and Month12
Secondary outcomes:
measure: Diagnosis of depression rate
timeFrame: Day 0
measure: Changes in adolescents' quality of live
timeFrame: Day 0, Month6 and Month12
measure: Prevalence of adolescent depression with depressed parent
timeFrame: Day 0
measure: Prevalence of parental depression with depressed adolescent
timeFrame: Day 0
measure: Risk and protection factors
timeFrame: Day 0
Other outcomes:
Locations:
city: Brest
country: France
facility: Dr Phan
city: Brest
country: France
facility: Dr Volant-Le-Berre
city: Brest
country: France
facility: Dr Wauters
city: Guilers
country: France
facility: Dr AUGUSTIN
city: Guissény
country: France
facility: Dr Le Grignou
city: Landerneau
country: France
facility: Dr Ac'h
city: Landivisiau
country: France
facility: Dr PITMAN
city: Le Relecq-Kerhuon
country: France
facility: Dr CHIRON
city: Le Relecq-Kerhuon
country: France
facility: Dr CONNAN
city: Locmaria-Plouzané
country: France
facility: Dr Cazuguel
city: Plougastel-Daoulas
country: France
facility: Dr Coat-Gourio
city: Plounéour-Trez
country: France
facility: Dr NABBE
Study officials:
References: