Clinical trial NCT06531577: Atmospheric Pressure and Epistaxis Relationship
Official title: Influence of Atmospheric Pressure on Patients Presenting to the Emergency Department With Epistaxis
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Atmospheric Pressure; Adverse Effect
Epistaxis Nosebleed
Keywords: atmospheric pressure
epistaxis
blood pressure
Lead sponsor: Saglik Bilimleri Universitesi
Sponsor class: OTHER
Collaborators: name: Ankara Etlik City Hospital
First posted: 2024-08-01
Enrollment: 600
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients over the age of 18 presenting to emergency department with epistaxis

Brief summary: In this study, investigators aim to understand the relationship between changes in atmospheric pressure and blood pressure, and to investigate whether these changes have an impact on the etiology of epistaxis.

Detailed description: This study aims to investigate the potential effects of changes in atmospheric pressure on epistaxis and, if such effects exist, to review treatment adjustments based on weather forecasts for hypertensive patients to prevent potential hypertensive emergencies and enhance patient comfort. This research poses no risk to patients and is purely observational and clinical in nature.

The study will be conducted prospectively over a period of 6 months at the Emergency Department of Ankara Etlik City Hospital, focusing on patients presenting with epistaxis.After initial evaluation upon presentation to the emergency department, patients will undergo routine emergency department monitoring for epistaxis, including physical examination, vital sign monitoring, evaluation of coagulation parameters, and hemoglobin levels. Apart from routine tests, no additional invasive or non-invasive procedures will be performed by us.

Data obtained from patients and daily atmospheric pressure parameters will be evaluated and analyzed.

Eligibility criteria: Inclusion Criteria:

Patients aged 18 and above Presenting to the emergency department with complaints of epistaxis, whether active or resolved.

Willing volunteers consenting to participate in the study. Residing in central districts of Ankara

Exclusion Criteria:

Patients under the age of 18. Pregnant individuals. Those with a history of maxillofacial surgery. Patients reporting a history of trauma at the time of admission. Patients stating they are from a city other than Ankara.

Primary outcomes:
measure: epistaxis
timeFrame: 24 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Etlik City Hospital
state: Yenimahalle
Study officials:
affiliation: ass. prof. of organization
name: gulsen akcay, ass. prof.
role: STUDY_DIRECTOR
References:
citation: Jelavic B, Majstorovic Z, Kordic M, Leventic M, Grgic MV, Baudoin T. Idiopathic epistaxis and meteorological factors: case-control study. B-ENT. 2015;11(4):267-73.
citation: Min SJ, Kang H, Kim KS, Min HJ. Minimal temperature, mean wind speed, and mean relative humidity are associated with spontaneous epistaxis in Seoul, Korea. Auris Nasus Larynx. 2021 Feb;48(1):98-103. doi: 10.1016/j.anl.2020.07.012. Epub 2020 Jul 25.