Clinical trial NCT05805306: Entre Herman@s: Promoting Health Among Latino MSM
Official title: Promoting HIV PrEP Among MSM: a Randomized Control Trial - Aim 3
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: HIV Infections
Keywords: Men Who Have Sex with Men
Latino men
HIV PrEP
Siblings
Lead sponsor: Charles Drew University of Medicine and Science
Sponsor class: OTHER
Collaborators: name: St. Johns Community Health
name: National Institute on Minority Health and Health Disparities (NIMHD)
First posted: 2023-04-10
Enrollment: 288
Sex: ALL
Minimum age (years): 18
Maximum age (years): 39
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This is a randomized controlled trial with an attention placebo control group. The goal of this study is to decrease HIV incidence in Latino men who have sex with men by engaging their siblings in PrEP-use promotion. In the intervention arm, siblings will be trained to engage their gay brother in PrEP conversations. In the control arm, siblings will be trained to engage their gay brother in conversations about vaccines to prevent COVID, Hepatitis A/B, or MPOX.


Eligibility criteria: Inclusion Criteria: Latino Men Who Have Sex with Men

1. self-identify as Latino
2. identify as male
3. be \<40 years old
4. report HIV-negative status
5. be willing to talk about MSM healthcare issues with a sibling
6. either (a) have never used PrEP or (b) stopped using PrEP at least 90 days ago
7. missing most recent COVID vaccine
8. missing Hepatitis (A or B) vaccines
9. missing Mpox vaccine
10. meet CDC's PrEP eligibility criteria (be HIV-negative; any male sex partner in the past six months; not in a monogamous partnership with a recently tested, HIV-negative man; and at least one of the following: any anal sex without condoms in past 6 months, any sexually-transmitted infection (STI) diagnosed or reported in past 6 months, or is in an ongoing sexual relationship with an HIV-positive male partner).

Exclusion Criteria: Latino Men Who Have Sex with Men

1. are unable to provide consent or
2. they do not meet any of the criteria above

Inclusion Criteria: Siblings

1. at least 18 years old
2. report a close relationship his/her LMSM brother \<40 years old
3. be willing to talk about MSM healthcare issues with his/her LMSM brother

Exclusion Criteria: Siblings

1. are unable to provide consent or
2. they do not meet any of the criteria above

Primary outcomes:
measure: Number of participants that start using PrEP
timeFrame: 90 days
measure: Number of participants that get vaccinated
timeFrame: 90 days
Secondary outcomes:
measure: Number of participants who increase their willingness to use PrEP
timeFrame: 90 days
measure: Number of participants who increase their willingness to get vaccinated
timeFrame: 90 days
Other outcomes:
Locations:
city: Los Angeles
country: United States
facility: Charles R. Drew University of Medicine and Science
state: California
Study officials:
affiliation: Charles Drew University of Medicine and Science
name: Homero del Pino, PhD, MS
role: PRINCIPAL_INVESTIGATOR
References: