Clinical trial NCT06716099: Clinical Characteristics and Outcome of Patients With Community Acquired Pneumonia
Official title: Clinical Characteristics and Outcome of Patients With Community Acquired Pneumonia
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Community Acquired Pneumonia (CAP)
Keywords: CAP
Pneumonia
clinical characteristics
Lead sponsor: Sohag University
Sponsor class: OTHER
First posted: 2024-12-04
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: participants will be more than 18 years old who admitted to sohag university hospital

Brief summary: the goal of this observational study is to evaluate the clinical characteristic and outcomes of patients with community-acquired pneumonia admitted to Sohag University Hospital.

the researcher will take medical history and clinical examination and investigations of participants .

the participants will visit the clinic after one month to be reevaluated again .

Detailed description: Community acquired pneumonia is acute infection of the pulmonary parenchyma that occurs in the community in a patient who has not been hospitalized within 14 days prior to onset of symptoms or hospitalized less than 2 days prior to the onset of symptoms the aim of the study typically focuses on examining the various factors that influence the presentation, management, and outcomes of individuals diagnosed with pneumonia that is acquired outside of a hospital or healthcare setting.

Type of the study: observational study

Outcomes of interest include:

I. Mortality (in hospital and 30 days). II. The need for further mechanical ventilation or ICU admission. III. Duration of hospital stay.

Eligibility criteria: Inclusion Criteria:

* The study will include patients ≥18 years old with community acquired pneumonia

Exclusion Criteria:

1. Patients already was diagnosed as active malignancy before admission
2. Patient on chemotherapy
3. HIV patients
4. Indication of mechanical ventilation on admission

Primary outcomes:
measure: improved
timeFrame: within one month
measure: patients developed complications
timeFrame: within one month
measure: Death of patient
timeFrame: within one month
Secondary outcomes:
measure: intensive care unit admission
timeFrame: within one month
Other outcomes:
Locations:
Study officials:
References:
citation: Han X, Liu X, Chen L, Wang Y, Li H, Zhou F, Xing X, Zhang C, Suo L, Wang J, Yu G, Wang G, Yao X, Yu H, Wang L, Liu M, Xue C, Liu B, Zhu X, Li Y, Xiao Y, Cui X, Li L, Cao B; CAP-China network. Disease burden and prognostic factors for clinical failure in elderly community acquired pneumonia patients. BMC Infect Dis. 2020 Sep 12;20(1):668. doi: 10.1186/s12879-020-05362-3.
citation: Iqbal N, Irfan M, Siddique F, Arshad V, Zubairi ABS. Factors predicting in-hospital mortality among patients admitted with community acquired pneumonia at a tertiary care hospital Karachi, Pakistan. Clin Respir J. 2020 Apr;14(4):328-334. doi: 10.1111/crj.13137. Epub 2020 Jan 2.
citation: Elsener C, Beeler PE, Battegay E, Bello B, Thienemann F. Risk Factors of In-Hospital Mortality in Patients Treated for Pneumonia at a Tertiary Care Centre in Switzerland. Respiration. 2020;99(8):637-645. doi: 10.1159/000508666. Epub 2020 Jul 7.
citation: Li HY, Guo Q, Song WD, Zhou YP, Li M, Chen XK, Liu H, Peng HL, Yu HQ, Chen X, Liu N, Lu ZD, Liang LH, Zhao QZ, Jiang M. Modified IDSA/ATS Minor Criteria for Severe Community-Acquired Pneumonia Best Predicted Mortality. Medicine (Baltimore). 2015 Sep;94(36):e1474. doi: 10.1097/MD.0000000000001474.
citation: Shoar S, Musher DM. Etiology of community-acquired pneumonia in adults: a systematic review. Pneumonia (Nathan). 2020 Oct 5;12:11. doi: 10.1186/s41479-020-00074-3. eCollection 2020.
citation: 1. Somberg J. Harrisons, Princiole of Internal Medicine. 20th ed. LWW; 2005