Clinical trial NCT00034619: A Phase 2 Trial of ALIMTA (LY231514, Pemetrexed) Plus Oxaliplatin Administered Every 21 Days for First-Line Treatment of Patients With Advanced Colorectal Cancer.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Colorectal Cancer
Lead sponsor: Eli Lilly and Company
Sponsor class: INDUSTRY
First posted: 2002-05-02
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to assess the antitumor activity of ALIMTA plus Oxaliplatin combination therapy in patients with previously untreated advanced colorectal cancer


Eligibility criteria: Inclusion Criteria:

* Diagnosis of primary cancer of the colon or rectum
* Must have measurable disease
* Must be able to comply with study procedure

Exclusion Criteria:

* Prior chemotherapy for advanced disease
* Pregnancy or lactation
* Candidates for surgical resection of one or more metastatic foci
* Second primary cancer
* Inability to take folic acid or vitamin B12

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Huntsville
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Alabama
city: Pittsfield
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Massachusetts
city: Kalamazoo
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Michigan
city: Latham
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: New York
city: Asheville
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: North Carolina
city: Goldsboro
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: North Carolina
city: Hendersonville
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: North Carolina
city: Winston-Salem
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: North Carolina
city: Columbus
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Ohio
city: Bend
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Oregon
city: Portland
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Oregon
city: Philadelphia
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Pennsylvania
city: Pittsburgh
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Pennsylvania
city: Reading
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Pennsylvania
city: Charleston
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: South Carolina
city: Ivins
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Utah
city: Ogden
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Utah
city: Provo
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Utah
city: St. George
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Utah
city: Bellevue
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Washington
city: Seattle
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Washington
city: Spokane
country: United States
facility: "For information on a site near you, call our call center at 1-877-CTLILLY (1-877-285-4559)"
state: Washington
Study officials:
References: