Clinical trial NCT06397170: Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients
Official title: Effects of Graded Repetitive Arm Supplementary Program Versus Task Based Training on Upper Limb Function in Stroke Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Upper Extremity Paresis
Motor Activity
Keywords: Stroke
Upper Extremity Paresis
Motor Activity
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-05-02
Enrollment: 38
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Patients will be divided into Group A (N=19) will receive Graded repetitive arm supplementary program and Patients in Group B (N=19)will receive Task based training.
Primary purpose: TREATMENT

Brief summary: To determine effects of graded repetitive arm supplementary program versus Task based training on Upper limb function in stroke patients.

Detailed description: This study will be Randomized Clinical Trial. A total of 38 stroke patients will be recruited by using non-probability convenience sampling Technique. Patients will be Randomized and allocated into two interventional groups based on the inclusion and exclusion criteria. Patients in Group A will receive Graded repetitive arm supplementary program and Patients in Group B will receive Task based training. All participants will receive the treatment for 40 minutes per session, 5 days per week for 5 weeks. For the evaluation of all participant scales like be Chedoke Arm and Hand Activity Inventory for clinical relevance, Fugl Mayer assessment scale for performance assessment, Action Reach Arm Test for coordination and dexterity and Motor Activity Log for functional assessment of Upper limb in stroke patients. D

Eligibility criteria: Inclusion Criteria:

* Patients with Sub acute stage of stroke.
* Patients with Ischemic and Haemorrhagic stroke.
* Patients with Cognition level on Mini Mental State Examination must be \> 24
* Patients with mild pain in upper extremity according to Numeric Pain Rating Scale
* Patients with Grade 2 active movements in affected extremity Tone of upper limb at Modified Ashworth Scale Grade 1+.

Exclusion Criteria:

* Other neurological disorders e.g. brain tumor, encephalitis, meningitis, brain abscess.
* Use of antipsychotics
* Use of drugs for spasticity.
* Patients with vestibular impairment.

Primary outcomes:
measure: Fugl Mayer assessment scale
timeFrame: 6 months
measure: The Motor Activity Log (MAL)
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Imran International Amjad
state: Punjab
Study officials:
affiliation: Riphah International University
name: Zeest hashmi
role: PRINCIPAL_INVESTIGATOR
References:
citation: Connell LA, McMahon NE, Watkins CL, Eng JJ. Therapists' use of the Graded Repetitive Arm Supplementary Program (GRASP) intervention: a practice implementation survey study. Phys Ther. 2014 May;94(5):632-43. doi: 10.2522/ptj.20130240. Epub 2014 Feb 6.
citation: Veerbeek JM, van Wegen E, van Peppen R, van der Wees PJ, Hendriks E, Rietberg M, Kwakkel G. What is the evidence for physical therapy poststroke? A systematic review and meta-analysis. PLoS One. 2014 Feb 4;9(2):e87987. doi: 10.1371/journal.pone.0087987. eCollection 2014.
citation: Yang CL, Waterson S, Eng JJ. Implementation and Evaluation of the Virtual Graded Repetitive Arm Supplementary Program (GRASP) for Individuals With Stroke During the COVID-19 Pandemic and Beyond. Phys Ther. 2021 Jun 1;101(6):pzab083. doi: 10.1093/ptj/pzab083.
citation: Lee HS, Lim JH, Jeon BH, Song CS. Non-immersive Virtual Reality Rehabilitation Applied to a Task-oriented Approach for Stroke Patients: A Randomized Controlled Trial. Restor Neurol Neurosci. 2020;38(2):165-172. doi: 10.3233/RNN-190975.