Clinical trial NCT06131099: Effects of Dohsa Hou Exercises on Functional Mobility
Official title: Effects of Dohsa Hou Exercises on Functional Mobility in Children With Down Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Down Syndrome
Keywords: Dohsa hou exercise
Down syndrome
Psychomotor therapy
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-11-14
Enrollment: 34
Sex: ALL
Minimum age (years): 6
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Its a randomized control trail, used to compare the effects of Dohsa hou exercises on functional mobility in children with Down syndrome. Subjects with Down syndrome meeting the predetermined inclusion and exclusion criteria will be divided into two groups using simple random sampling technique.
Primary purpose: TREATMENT

Brief summary: Trisomy 21 is a condition where there's an extra chromosome 21, which leads to a set of clinical signs called Down syndrome. Down syndrome is one of the most complicated genetic conditions that can occur post-term and is the most commonly survivable form of aneuploidy of the autosomal chromosomes.

Dohsa hou is a type of psychomotor therapy that helps improve psychological problems by using bodily movements, sensation and relaxation experience. It was first developed under the name psycho-rehabilitation to help children with cerebral palsy improve their movements and posture. By using Dohsa hou movement's issues were effectively addressed in children with cerebral palsy, despite their physical limitations being caused by physiological disorders. There are two kind of treatments of Dohsa hou exercises that are relaxation therapy to decrease the stress level in body and other one is to align the body to correct the posture and movements of the body.

Detailed description: This study will be a randomized control trial, used to compare the effects of Dohsa hou exercises on functional mobility in children with Down syndrome. Subjects with Down syndrome meeting the predetermined inclusion and exclusion criteria will be divided into two groups using simple random sampling techniques. Assessment will be done by using Test of trunk impairment scale and Time Up and Go Test. Subjects in one group will be treated with Dohsa hou therapy and in other group standard treatment protocol.

Eligibility criteria: Inclusion Criteria:

1. Down syndrome
2. Age group of 6 to 12 years old
3. Male and female (both genders)
4. Body mass index (BMI) within normal range \<95%
5. Absence of any psychiatric and physical illness at the time of participation.

Exclusion Criteria:

1. Uncontrolled seizures
2. Any kind of autoimmune diseases
3. Registered visually impaired or hearing issues
4. Severe atlanto axial instability
5. Congenital heart defects (CHD)
6. Unable or unwilling to understand the commands

Primary outcomes:
measure: Trunk impairment scale
timeFrame: 6 weeks
measure: Time up and go
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Riphah International University
state: Punjab
Study officials:
affiliation: Riphah International University
name: Muhammad Asif Javed, MS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Fujino H, Moritsugu A. Dohsa-hou for unexplained regression in Down syndrome in a 19-year-old man: A case report. Clin Case Rep. 2022 May 15;10(5):e05827. doi: 10.1002/ccr3.5827. eCollection 2022 May.