Clinical trial NCT06021834: Effect of Physical Rehabilitation in Patients With Parkinson's Disease
Official title: Effect of Physical Rehabilitation on Cardiorespiratory Parameters, Postural Balance and Sociopsychological and Cognitive Variables in Patients With Parkinson's Disease
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Parkinson Disease
Keywords: "Parkinson Disease"
"cognitive function"
"postural balance"
"physical rehabilitation"
Lead sponsor: Faculty of Medicine, Sousse
Sponsor class: OTHER
First posted: 2023-09-01
Enrollment: 40
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: This is a prospective study. The aim of this study is to investigate the effect of exercise retraining on cardiorespiratory parameters, postural balance, sociopsychological variables, and cognitive function in subjects with Parkinson's disease.

There will be two measurement sessions, one pre-intervention and one post-intervention (measuring cardiorespiratory parameters, evaluating dynamic and static postural balance, and assessing cognitive function).

Detailed description: this is a 12-week prospective study with the theme that I wish to develop in this context entitled "the effect of exercise retraining on cardiorespiratory parameters, postural balance, sociopsychological variables, and cognitive function in subjects with Parkinson's disease".

There will be two measurement sessions, one pre-intervention and one post-intervention (measuring cardiorespiratory parameters, evaluating dynamic and static postural balance, and assessing cognitive function).

The recruited subjects will be randomly assigned to two groups: a control group and an experimental group. The subjects will be invited to attend the program three times per week.

The control group will engage in an endurance training program, while the experimental group will participate in a combined endurance training and cognitive training program

Eligibility criteria: Inclusion Criteria:

* Diagnosed with Parkinson's disease according to the Movement Disorder Society (MDS) 2015 criteria.
* Mild to moderate stage according to the Hoehn and Yahr scale.
* No hearing or visual impairments that could hinder the integration and implementation of the rehabilitation protocol.
* Has the ability to communicate and walk.
* Patient has been stable on treatment for 3 months.

Exclusion Criteria:

* A contraindication to engaging in cardiovascular physical activity
* A Montreal Cognitive Assessment score (MoCA ) of less than 24.
* A current psychiatric disorder that could make it difficult or dangerous to adhere to the research protocol.
* Musculoskeletal impairments or excessive pain in any joint that could limit participation in an exercise program.
* Treatment with sedative medications

Primary outcomes:
measure: Cardiorespiratory Parameters
timeFrame: There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient)
measure: Postural Balance
timeFrame: There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient)
measure: Depression
timeFrame: There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient)
measure: Cognitive Function
timeFrame: There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient)
Secondary outcomes:
measure: Strength
timeFrame: There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient)
Other outcomes:
Locations:
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