Clinical trial NCT06597318: Trends of Patient-reported Outcome Measures (PROMs) in Multimorbid Medical Patients Hospitalized for an Acute Illness
Official title: Trends of Patient-reported Outcome Measures (PROMs) in Multimorbid Medical Patients Hospitalized for an Acute Illness
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: PROM
PREM
Quality of Care
Internal Medicine
Lead sponsor: University of Lausanne Hospitals
Sponsor class: OTHER
Collaborators: name: Insel Gruppe AG, University Hospital Bern
name: University Hospital, Geneva
name: University Hospital, Zürich
name: University Hospital, Basel, Switzerland
First posted: 2024-09-19
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with 2 or more chronic diseases, hospitalized in general internal medicine divisions of all five Swiss university hospitals

Brief summary: currently, PROMs and PREMs are not routinely collected and compared among medical inpatients of Swiss university hospitals, nor is a standard set of PROMs and PREMs available for use in Swiss hospitals. The project aims to examine trends in patient-reported outcomes (PROMs), including symptoms, quality of life, and distress, in multimorbid hospitalized patients from admission to 30 days post-discharge. It will also investigate whether PROMs at discharge are linked to the risk of readmission or emergency visits and explore how these outcomes differ in patients who receive low-value care. Additionally, the project will assess the relationship between patient-reported experiences (PREMs) and the provision of low-value care during the hospital stay.


Eligibility criteria: Inclusion Criteria:

* eligible for the LUCID registry (CER-VD AO_2023-00029) \[Age ≥ 18 years, hospitalized in one of the five participating university hospitals (Geneva, Lausanne, Bern, Zürich, Basel), after 01.01.2014, and admitted to general internal medicine wards
* Multimorbid patients (2 or more chronic diseases, defined as chronic conditions defined by international classification of diseases, 10th revision, codes with an estimated expected duration of at least 6 months or based on a clinical decision.
* Acute illness
* Signature of study specific informed consent

Exclusion Criteria:

* Not able to speak French, German or English
* Foreseen length of stay of less than 4 days (estimated by study collaborators)
* Prior inclusion in the TRADUCE study
* Incapacity of discernment, i.e. cognitive impairment which could interfere with the ability to fill in PROMs tools

Primary outcomes:
measure: Correlation of PROMS with the risk of readmission
timeFrame: Day 1, Day 3, at the day of discharge (approximately day 8) and Day 30 after discharge from Hospital
Secondary outcomes:
measure: Correlation of PROMs at discharge and risk of hospital readmission or ED visits
timeFrame: Day 30 after discharge from hospital
measure: Exploration of PROMs in patients who receive low-value care
timeFrame: Day 1, Day 3, at the day of discharge (approximately day 8) and Day 30 after discharge from Hospital
measure: Explore PREMs
timeFrame: Since 24 hours after beginning of the hospitalization up to Discharge from Hospital (approximately day 8)
Other outcomes:
Locations:
city: Lausanne
country: Switzerland
facility: Lausanne University Hospital
state: Vaud
Study officials:
affiliation: University Hospital, Geneva
name: Jerome Stirnemann, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Bern University Hospital
name: Carole Aubert, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Zürich University Hospital
name: Florence Vallelian Cervetto, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Basel University Hospital
name: Stefano Bassetti, MD
role: PRINCIPAL_INVESTIGATOR
References: