Clinical trial NCT03688542: Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
Official title: Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Polypharmacy
Inappropriate Prescribing
Keywords: Deprescribing
Inappropriate Medication
Nursing Homes
Lead sponsor: University of Geneva, Switzerland
Sponsor class: OTHER
First posted: 2018-09-28
Enrollment: 56
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Older people residing in nursing homes (NH) are frequently polymedicated and often prescribed potentially inappropriate medications. Deprescribing has been proposed as a way to reduce the number of drugs they receive and their exposure to harmful treatments.

The objectives of this study are 1) To evaluate the effect of a deprescribing-specific interdisciplinary quality circle module on the use of potentially inappropriate medication in nursing-home residents. 2) To determine the effective strategies to reach and implement deprescribing consensus resulting of said quality circle module.


Eligibility criteria: Inclusion Criteria:

Nursing homes taking part in the study must have

* a geriatric of psycho-geriatric mission;
* been part of their cantonal pharmaceutical assistance program for at least a year.

Exclusion Criteria:

* None

Primary outcomes:
measure: Percentage of Potentially Inappropriate Galenic Units
timeFrame: 12 months
measure: Number of Potentially Inappropriate Defined Daily Doses (DDDs) Per Average Resident and Per Day
timeFrame: 12 months
Secondary outcomes:
measure: Number of Potentially Inappropriate DDD to Avoid
timeFrame: 12 months
measure: Number of Potentially Inappropriate DDD to Reevaluate
timeFrame: 12 months
measure: Number of Hospital Days
timeFrame: 12 months
measure: Mortality Rate
timeFrame: 12 months
measure: Number of Falls Per Average Resident and Per Year
timeFrame: 12 months
measure: Percentage of Residents With at Least One Day of Physical Restraints Use
timeFrame: 12 months
Other outcomes:
Locations:
city: Lausanne
country: Switzerland
facility: Centre de Pharamacie Communautaire
state: Vaud
Study officials:
affiliation: University of Geneva
name: Olivier Bugnon, Prof
role: STUDY_DIRECTOR
References:
citation: Cateau D, Ballabeni P, Niquille A. Effects of an interprofessional deprescribing intervention in Swiss nursing homes: the Individual Deprescribing Intervention (IDeI) randomised controlled trial. BMC Geriatr. 2021 Nov 19;21(1):655. doi: 10.1186/s12877-021-02465-7.
citation: Cateau D, Ballabeni P, Niquille A. Effects of an interprofessional Quality Circle-Deprescribing Module (QC-DeMo) in Swiss nursing homes: a randomised controlled trial. BMC Geriatr. 2021 May 1;21(1):289. doi: 10.1186/s12877-021-02220-y.
citation: Cateau D, Ballabeni P, Mena S, Bugnon O, Niquille A. Deprescribing in nursing homes: Protocol for nested, randomised controlled hybrid trials of deprescribing interventions. Res Social Adm Pharm. 2021 Apr;17(4):786-794. doi: 10.1016/j.sapharm.2020.05.026. Epub 2020 May 27.