Clinical trial NCT06707675: Chronotype and Myofascial Pain Syndrome,
Official title: Chronotype and Quality of Life in Patients with Myofascial Pain Syndrome, a Cross-Sectional Study
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Myofascial Pain Syndrome, Diffuse
Lead sponsor: Afyonkarahisar Health Sciences University
Sponsor class: OTHER
First posted: 2024-11-27
Enrollment: 500
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients aged 18-65 who applied to Afyonkarahisar Health Sciences University (AFSU) Physical Medicine and Rehabilitation Polyclinic and who have had neck and back pain complaints for at least 3 months were diagnosed with myofascial pain syndrome through anamnesis and physical examination.

Brief summary: The aim of this study is to examine chronotype preferences in myofascial pain syndrome and to investigate its relationship with pain severity, disability and quality of life.

Detailed description: Myofascial pain syndrome (MPS) is defined as sensory, motor, and autonomic symptoms caused by myofascial trigger points. Trigger points are defined as tender points in discrete taut bands of stiffened muscle that cause local and referred pain, among other symptoms. The mechanical and psychological stress of the muscle can activate trigger points and cause pain over a wide area. MyofascialPainSyndrome (MPS) is considered one of the most common chronic musculoskeletal pains. Various studies have shown that it is often associated with depression and anxiety. It is important to focus on modifiable biopsychosocial factors, while paying attention to aspects that cannot be changed, such as attitudes, neuroticism, and trait anxiety, which are known to be somewhat stable over time. Knowing these factors is necessary to improve patients' quality of life and regain their functions.

Pain in patients with MAS can cause sleep disorders such as non-restorative sleep or difficulty initiating or maintaining sleep. It is estimated that 70-80% of patients with MAS experience sleep disorders. Patients with insomnia, especially those living in urban affluent areas, are at risk of developing MAS later in life. Morning-evening preference is an inter-individual difference, also known as diurnal or circadian preference.

The circadian rhythm is controlled by the endogenous circadian clock, which has a genetic basis and is affected by exogenous factors. Due to these individual differences, individuals' energy levels during the day vary so much that people prefer to be active at different times of the day. Morning Type individuals prefer to be active early in the day, while evening type individuals prefer to be active later in the day. Individuals who are between these types and morning or evening preference are called intermediate types. Morning preference is affected by biological factors (e.g., body temperature, cortisol, melatonin), technological and social factors (e.g., electronic media, lighting, TV screens, daily life activities), and environmental factors (e.g., climate, latitude, longitude). In addition, morning preference is related to personality, health, eating habits and psychological well-being. Morning people are more conscientious and more prone to healthy behaviors. On the other hand, evening preference can lead to behavioral problems (e.g., depression, loneliness), personality disorders (substance abuse, eating disorders, internet addiction, daytime sleepiness) and poor academic performance. A study in which 1548 people with fibromyalgia (FMS) were assessed with an online survey that included questions about sleep quality, well-being, pain, chronotype and FMS showed that late chronotypes were more affected by fibromyalgia.

Another study investigating the relationships between chronotypes and musculoskeletal pain showed that evening and intermediate chronotypes were associated with musculoskeletal pain, but mental distress, insomnia, and comorbidities also played a role in these relationships. The aim of this study is to examine chronotype preferences in myofascial pain syndrome and to investigate its relationship with pain severity, disability and quality of life.

Eligibility criteria: Inclusion Criteria:

* neck-back pain for at least 3 months
* diagnosis of myofascial pain syndrome by anamnesis and physical examination

Exclusion Criteria:

* Cervical Radiculopathy/Myelopathy
* Recent injection or physical therapy within the last 3 months
* Neck and shoulder surgery
* Neurological and inflammatory diseases
* Pregnancy
* Malignancy

Primary outcomes:
measure: VAS
timeFrame: "Baseline"
measure: Pressure Algometry Measurements: (kg/cm2)
timeFrame: "Baseline"
measure: Cervical joint range of motion
timeFrame: "Baseline"
measure: Morningness Eveningness Questionnaire
timeFrame: "Baseline"
Secondary outcomes:
measure: Neck Pain Disability Scale
timeFrame: "Baseline"
measure: Pittsburg Sleep Quality Index (PSQI)
timeFrame: "Baseline"
measure: Beck Depression Anxiety Inventory
timeFrame: "Baseline"
measure: The Pain Catastrophizing Scale
timeFrame: "Baseline"
measure: SF-12
timeFrame: "Baseline"
Other outcomes:
Locations:
Study officials:
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