louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06399549: Effects of Dead Bug vs. Mc Gill Exercises on Pain, QOL and Core Stability in Patient With Chronic Nonspecific LBP
Official title: Effects of Dead Bug vs. Mc Gill Exercises on Pain, Quality of Life and Core Stability in Patient With Chronic Nonspecific Low Back Pain
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Low Back Pain
Lead sponsor: Superior University
Sponsor class: OTHER
First posted: 2024-05-03
Enrollment: 44
Sex: ALL
Minimum age (years): 30
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: DIAGNOSTIC

Brief summary: Low back pain is one of the most common conditions for which patients are sent to physiotherapy clinics. 84% of people have experienced it at least once in their lifetime, and over 50% have experienced it more than once, according to research. However, diagnosis and, in particular, the provision of specialized back pain therapy remain difficult.

Detailed description: This study aims to compare the effects of dead bug vs. Mc Gill exercises on pain, quality of life and core stability in patient with chronic nonspecific low back pain. It will be a randomized clinical trial study. The sample size of study will be 44 participants (22 in each group). Data will be collected from Azra Naheed Hospital. Data will be collected within 6 months after approval of synopsis. Group A will follow dead bug exercises and Group B will follow Mc Gill exercises (Curl up, Side Bridge and Bird Dog). The patients in both groups will be performed the corresponding exercises 3 days a week and 10 repetitions of each exercise for a period of 6 weeks and a rest interval of 2 minutes between exercises. The exercises will be taught to the patients at the end of the first session in both groups. The data will be analyzed using SPSS version 24 for Windows software. Statistical significance will be set at P ≤ 0.05. Normality of data will be assessed through Kolmogorov-smirnov test. Difference between pre-treatment and post-treatment readings will be calculated using Paired sample t-test for parametric data. For non-parametric data Wilcoxon test will be used. Independent sample t test will be used for parametric data and Mann Whitney test will be used for non parametric data.

Eligibility criteria: Inclusion Criteria:

* Age 30-50 years
* Patient with the history of 3 months nonspecific low back pain
* Pain intensity (3-7) according to VAS score

Exclusion Criteria:

* Spinal stenosis
* Neurological dysfunction
* Systemic disease
* Pregnancy
* Infections
* Carcinoma
* Any fracture or deformity

Primary outcomes:
measure: VA
timeFrame: 6 Months
Secondary outcomes:
measure: SF36
timeFrame: 6 Months
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Sir Ganga Ram Hospital Physiotherapy department , Mozang
state: Punjab
Study officials:
References:
Clinical trial NCT05627349: The Evaluation for Fu's Subcutaneous Needling (FSN) in Carpal Tunnel Syndrome.
Official title: The Evaluation for Fu's Subcutaneous Needling in Carpal Tunnel Syndrome: a Randomized Controlled Trial.
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Carpal Tunnel Syndrome
Keywords: Fu's Subcutaneous Needling, carpal tunnel syndrome
Lead sponsor: China Medical University Hospital
Sponsor class: OTHER
First posted: 2022-11-25
Enrollment: 60
Sex: ALL
Minimum age (years): 20
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to evaluate the efficacy of Fu's Subcutaneous Needling (FSN) in carpal tunnel syndrome (CTS). The main questions it aims to answer are:

* Dose FSN improve the symptoms of CTS?
* Dose FSN decrease cross section area of median nerve in CTS patients?
* Dose FSN have the effect of electrophysiology exam in CTS patients? Participants will receive wrist splinting and FSN treatment respectively. Researchers will compare wrist splinting group with FSN group to see if FSN being effective for CTS.


Eligibility criteria: Inclusion Criteria:

1. Male or female aged 20-85 years old.
2. Meet the diagnosis of mild to moderate carpal tunnel syndrome.
3. If the patient has carpal tunnel syndrome in both hands, choose the side with mild or moderate carpal tunnel syndrome.
4. After being explained, join the trial voluntarily and sign the subject's consent form.

Exclusion Criteria:

1. Caused by trauma or mass lesion.
2. Thenar muscle atrophy.
3. Electrophysiological examination revealed severe CTS.
4. Chronic kidney disease, rheumatoid arthritis, abnormal thyroid function, diabetes.
5. Psychiatric history or incapable of cooperating with the investigator.
6. Pregnancy.
7. History of substance abuse or long-term steroid use.
8. History of median nerve surgery.
9. Those who do not sign the consent form.

Primary outcomes:
measure: Change of Boston Carpal Tunnel Questionnaire (BCTQ)
timeFrame: Change from baseline at one month after treatment.
measure: Change of electrophysiology exam
timeFrame: Change from baseline at one month after treatment.
measure: Change of cross section area of median nerve in ultrasound
timeFrame: Change from baseline at one month after treatment
Secondary outcomes:
Other outcomes:
Locations:
city: Zhubei
country: Taiwan
facility: China Medical University Hsinchu Hospital
state: Hsinchu County
Study officials:
affiliation: China Medical University, China
name: Chih Ying Wu, MD
role: STUDY_CHAIR
References:
Clinical trial NCT05168449: The Impact of Pharmacist-led Mobile Application on Adherence in Chronic Kidney Disease Patients
Official title: The Impact of Pharmacist - Led Mobile Application on Medication Adherence and Efficacy in Chronic Kidney Disease Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Kidney Diseases
Adherence, Medication
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2021-12-23
Enrollment: 86
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The aim of the study is to assess the impact of pharmacist led mobile application on adherence and efficacy of medication in chronic kidney disease patients

Detailed description: This is a prospective randomized two group pharmacist-led interventional study that will be conducted in a private nephrology clinic. The study will involve introduction of the mobile phone applications to chronic kidney disease patients to improve their adherence to the prescribed medications.

Recruited patients will be randomly divided in two groups; intervention group and control group, with baseline evaluation of outcomes to be measured.

Control group will be provided with usual care. Intervention group will be provided in addition to the usual care, with an access to the mobile application after a simple training for app usage. Both groups will be followed for a period of 3 months.

The study will include the development, validation and the testing for evaluating the specially designed mobile application.

Eligibility criteria: Inclusion Criteria:

* Stages 2-5 of chronic kidney disease
* Literate
* Ownership of android smart phone compatible with the application
* Poly-pharmacy

Exclusion Criteria:

* On dialysis due to loss of kidney function
* Pregnancy due to altered physiology

Primary outcomes:
measure: Change in medication adherence
timeFrame: Change from baseline at 3 months
Secondary outcomes:
measure: Change in estimated glomerular filtration rate/ creatinine clearance
timeFrame: Change from baseline at 3 months
measure: Change in systolic and diastolic blood pressure
timeFrame: Change from baseline at 3 months
measure: Change in HbA1c
timeFrame: Change from baseline at 3 months
measure: Change in mobile application usability and acceptability by patients
timeFrame: Change from baseline at 3 months
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Private Clinic
Study officials:
affiliation: Teaching Assistant
name: Shaza Gamal, Bsc
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00247949: Accuracy of Non-invasive Continuous CO2-Monitoring
Official title: The Accuracy of Non-invasive Continuous Carbon Dioxide Monitoring by the Sentec V-Sign Digital Monitor System
Study type: OBSERVATIONAL
Overall status: TERMINATED
Conditions: Blood Gas Monitoring, Transcutaneous
Keywords: carbon dioxide
monitoring
major surgery
repeated blood gas testing
carbon dioxide monitoring
Lead sponsor: University Hospital, Basel, Switzerland
Sponsor class: OTHER
Collaborators: name: SenTec AG, Ringstrasse 39, CH-4106 Therwil
First posted: 2005-11-02
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients undergoing surgery in general anesthesia and with clinical indication for repeated arterial blood gas sampling

Brief summary: Arterial carbon dioxide partial pressure (PaCO2) is an essential indicator of ventilation and respiratory function. It is routinely tested invasively by arterial blood gas analysis (ABGA) but recently developed miniaturized carbon dioxide tension sensors promise non-invasive and continuous transcutaneous PCO2 (PtcCO2) monitoring. We, the researchers at University Hospital, Basel, Switzerland, determined the accuracy of two PtcCO2 monitors (TOSCA 500 with Sensor 92, Linde Medical Sensors AG, Basel; and Sentec Digital Monitor with V-Sign Sensor, Sentec AG, Therwil) for measurement of single values and trends in PaCO2 in critically ill patients, using ABGA as a reference.

Detailed description: Measurement of SO2 is used in nearly every patient receiving anesthesia or sedation, whereas monitoring of pCO2 is important in patients during and shortly after major surgery and in critically ill patients. But measurement of pCO2 requires arterial blood sampling and laboratory testing. Non-invasive monitors for continuous assessment of arterial pCO2 have been developed but their accuracy and feasibility were insufficient to make them useful in the clinical setting. Recently, a new digital system for continuous and non-invasive monitoring of arterial pCO2 and SO2 has been introduced (SenTec Digital Monitor System, SenTec AG, Therwil, Switzerland). This present study has been designed to evaluate the accuracy of the SenTec V-SignTM monitoring system for measuring pCO2 in comparison with repeated arterial blood gas testing in the operation room and in the intensive care unit.

Eligibility criteria: Inclusion Criteria:

* Patients older than 18 years with clinical indication of repeated arterial blood gas analyses

Exclusion Criteria:

* No informed consent

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Basel
country: Switzerland
facility: University Hospital
state: CH
Study officials:
affiliation: Department of Anaesthesia University Hospital Basel
name: Daniel Bolliger, Dr.
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04960449: Arthroscopic Treatment of Partial Rotator Cuff Tears in Shoulder Joint
Official title: Arthroscopic Treatment of Partial-thickness Rotator Cuff Tendon Tears
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Rotator Cuff Tears
Lead sponsor: Peking University Third Hospital
Sponsor class: OTHER
First posted: 2021-07-13
Enrollment: 50
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients diagnosed with partial-thickness rotator cuff tendon tears. Partial rotator cuff tears can be divided into three categories, bursa side tears, tendon tears and joint side tears. Studies have found that rotator cuff tendon tears account for 55% of partial tears, compared to the other two types of partial tears, there has been very little research on partial-thickness rotator cuff tendon tears, which has no consensus on diagnosis and treatment.

Brief summary: A retrospective analysis was performed on patients with partial-thickness rotator cuff tendon tears who underwent arthroscopic surgery from August 2006 to December 2011. To evaluate functional outcomes and tendon healing after arthroscopy.

Detailed description: To study the surgical method and clinical effect of arthroscopic treatment of rotator cuff tendon tear. Retrospective analysis was performed on patients with rotator cuff tendon tears who underwent arthroscopic surgery from August 2006 to December 2011. Preoperative X-ray and MRI were performed. Rotator cuff repair was performed during the operation. UCLA shoulder scoring scale was used to evaluate the shoulder joint at preoperative and final follow-up.

Eligibility criteria: Inclusion Criteria:

* From August 2006 to December 2011, patients with partial-thickness rotator cuff tendon tears who underwent arthroscopic surgery in our department and were successfully followed up.

Exclusion Criteria:

* Patients with frozen shoulder and shoulder joint instability.

Primary outcomes:
measure: The function of shoulder joint was analyzed 1 year after arthroscopy.
timeFrame: 1 year after operation
measure: The function of shoulder joint was analyzed 2 years after arthroscopy.
timeFrame: 2 years after operation
measure: The function of shoulder joint was analyzed 5 years after arthroscopy.
timeFrame: 5 years after operation
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Peking University Third Hospital
Study officials:
affiliation: Peking University Third Hospital
name: jian xiao
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04613349: FArial NErf MRI in the Preoperative Assessment of PArotide Tumors
Official title: FArial NErf MRI in the Preoperative Assessment of PArotide Tumors
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Parotid Tumor
Lead sponsor: Fondation Ophtalmologique Adolphe de Rothschild
Sponsor class: NETWORK
First posted: 2020-11-03
Enrollment: 88
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient candidate for first line surgery for a parotid tumor

Brief summary: 1. st visit: Inclusion, 3Tesla injected parotid MRI performed as part of routine care for characterization, to which two specific high resolution sequences will be added. Evaluation of the exact position of the parotid tumor relative to the trunk of the facial nerve and its first branches, classification into two categories: on contact (≤ 5 mm) or at a distance (\> 5 mm).
2. nd visit: Surgical intervention of the parotid tumor. The surgeon will specify the same data as that collected by the radiologists after the MRI.
3. rd visit: Post-operative consultation in the week following the intervention. The surgeon will look for the occurrence of post-operative facial paralysis.


Eligibility criteria: Inclusion Criteria:

* Patient over 18 years old
* Patient candidate for first line surgery for a parotid tumor
* Parotid tumor located near the trunk of the facial nerve and or its first branches of division according to the clinical examination of the ENT surgeon and the imaging data
* Affiliate or beneficiary of a social security scheme
* Written consent to participate in the study

Exclusion Criteria:

* Personal history of parotid homolateral surgery
* Absolute or relative contraindication to MRI
* Known hypersensitivity to gadolinic contrast media
* Pre or post operative period of a liver transplant
* Patient benefiting from a legal protection measure
* Pregnant or lactating woman
* Patient who has already benefited from a preoperative MRI to characterize a complete, well conducted and interpretable parotid lesion

Primary outcomes:
measure: measurements by the radiologist on the high resolution 3Tesla MRI with specific sequences.
timeFrame: day 0
measure: assessment by the surgeon during the excision surgery of the parotid lesion
timeFrame: day 0
Secondary outcomes:
Other outcomes:
Locations:
city: Paris
country: France
facility: Fondation A De Rothschild
Study officials:
References:
Clinical trial NCT03183349: Immediate Implant Placement With Platlet Rich Fibrin as Space Filling Material Versus the Use of Deprotienized Bovine Bone (Tutogen) in Maxillary Premolars.
Official title: Immediate Implant Placement With Platlet Rich Fibrin as Space Filling Material Versus the Use of Deprotienized Bovine Bone (Tutogen) in Maxillary Premolars. A Randomized Controlled Clinical Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Immediate Dental Implant
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2017-06-12
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: 20 subjects suffering from non restorable maxillary premolar teeth will be randomly devided into two groups. the selected teeth will be extracted and immeiate implants will be placed in all subjects. the first group will recieve deprotienized bovine bone (tutogen) to fill the buccal space between the implant and the bone, the second group will recieve platlet rich fibrin to fill the buccal space between the implant and the bone


Eligibility criteria: Inclusion Criteria:

* non restorable maxillary premolars non smoker free from any systemic disease or medication that could impair normal bone healing

Exclusion Criteria:

* any systemic disease that could affect bone healing patient with lesion related to the surgical site

Primary outcomes:
measure: Patient morbidity
timeFrame: 14 days
Secondary outcomes:
measure: crestal bone loss
timeFrame: 3 months
measure: implants stability quotient
timeFrame: 3 months
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT00159549: Long Term Effect of an Education and Training Program for Patients With Chronic Obstructive Pulmonary Disease
Official title: Long Term Effect of an Education and Training Program for Patients With Chronic Obstructive Pulmonary Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: Patient education
Lead sponsor: Norwegian University of Science and Technology
Sponsor class: OTHER
Collaborators: name: Helse Nord-Trøndelag HF
First posted: 2005-09-12
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 99
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A parallell group study comparing the effect of an education program with an education and training program for patients with COPD. 30 participants in each group. Participants self-select which group they wanted to be in. Main outcome is SGRQ (a HQoL for patients with COPD).


Eligibility criteria: Inclusion Criteria:

* Patients diagnosed with COPD (FEV1\<75% of expected) who have the ability to conversation and active participation will be included.

Exclusion Criteria:

-

Primary outcomes:
measure: St Geoprg Respiratory Questionnaire (SGRQ)
Secondary outcomes:
measure: COPD-Efficacy scale (Norwegian short version), Breathing Problems Questionnaire (BPQ), journal examinations, FVC, FEV1, six minutes walking test with registration of shortness of breath and pulseoxymetrical data.
Other outcomes:
Locations:
city: Trondheim
country: Norway
facility: Department of Community Medicine and General Practice
Study officials:
affiliation: Norwegian University of Science and Technology
name: Aslak Steinsbekk, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Lomundal BK, Steinsbekk A. Observational studies of a one year self-management program and a two year pulmonary rehabilitation program in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2007;2(4):617-24.
citation: Steinsbekk A, Lomundal BK. Three-year follow-up after a two-year comprehensive pulmonary rehabilitation program. Chron Respir Dis. 2009;6(1):5-11. doi: 10.1177/1479972308098387.
Clinical trial NCT04726449: Observatory of Psychiatric Symptoms and Their Somatic Causes in Urgent Medical Care
Official title: Observatory of Psychiatric Symptoms and Their Somatic Causes in Urgent Medical Care (OPOSSUM)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Neurologic Disorder
Psychiatric Disorder
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2021-01-27
Enrollment: 148
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient using emergency department for a psychiatric symptom

Brief summary: Use of emergency department for psychiatric symptoms always addresses the question of a potential somatic cause to the symptoms. Despite the wide-spread use of standard biology test and systematic brain imaging (for a first episode), there are still up to 5% of patients sent in psychiatric wards that actually have a somatic explanation to their symptoms which induces an important delay in the diagnostic assessement We hypothesized that simple neurological clinical examination along with fast psychometric screening tests in the Emergency Room (ER) could help the physicians to better screen the patients and thus prevent inaccurate post-emergency orientation.

Every patient visiting the ER for psychiatric symptoms will be included. The usual physical examination by the ER physician will be associated with two psychometric tests (namely the Clock-drawing test and Frontal Assessment Battery test).

The follow up will be made after 3 months in order to have the final diagnosis. Neurological data and data from the FAB test and the Clock-drawing test will be compared between patients who were finally given a psychiatric diagnosis versus patients with a somatic diagnosis at the end of the follow up period.


Eligibility criteria: Inclusion Criteria:

* Age\> 18 years old
* Patient consulting the emergency room for psychiatric recourse
* Benefiting from a consultation with a psychiatrist in the emergency room
* Patient affiliated to a social security scheme

Exclusion Criteria:

* Pregnant or breastfeeding women
* Patient objecting to the conduct of this study and the collection of health data
* Patient with motor disorders preventing the performance of a test requiring a pencil
* Patient sedated before treatment in the emergency room
* Patient with visual disturbances

Primary outcomes:
measure: Somatic or psychiatric nature of the final diagnosis given to the patient
timeFrame: At 3 month
Secondary outcomes:
Other outcomes:
Locations:
city: Lyon
country: France
facility: Service Accueil des Urgences, Hopital Edouard Herriot
state: Rhône
Study officials:
affiliation: Hôpital Edouard Herriot, HCL
name: KARIM TAZAROURTE, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: