Clinical trial NCT05742542: The Effects of High vs. Low Time Spent Near VO2max During Two Work-matched High Intensity Interval Training.
Official title: The Effects of High vs. Low Time Spent Near VO2max During Two Work-matched High Intensity Interval Training.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: VO2max
Keywords: VO2max
Exercise
Aerobic
Performance
Training
Lead sponsor: University of the State of Santa Catarina
Sponsor class: OTHER
First posted: 2023-02-24
Enrollment: 15
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: The order of training protocols was randomized and the training programs had a washout period of at least one month.
Primary purpose: TREATMENT

Brief summary: Maximal oxygen uptake (VO2max) is used to define cardiorespiratory fitness, which is important to health and sport performance in humans. Although different types of training can improve VO2max, the high intensity interval training is recognized as one of the best ways to do it. Furthermore, it has long been speculated that high intensity interval training that elicits a high time spent near VO2max could be the best way to improve VO2max. However, this theory has not been verified. Thus, the investigators performed a randomized controlled trial with crossover in healthy individuals who underwent two high intensity interval training protocols of two weeks, being a workout with longer and other with shorter time spent near VO2max.

Detailed description: Fifteen participants were enrolled in a randomized trial with crossover to perform two weeks of high intensity interval training with high (i.e., five times 2 minutes of work and 1 minute of recovery; T-2min:1min) or low (i.e., ten times 1 minutes of work and 30 seconds of recovery; T-1min:30seg) time spent near VO2max. The work intensity was adjusted at 85% and 87% of power output achieved at the end of incremental test for the first and second week, respectively. Before and after the T-2min:1min and T-1min:30seg, the participants performed tests to determine VO2max, lactate threshold, muscle oxidative capacity, pulmonary oxygen uptake kinetics, power output achieved at the end of incremental test, and power output related to Wingate anaerobic test. The training programs had a washout period of at least one month.

Eligibility criteria: Inclusion Criteria:

* Male ≥ 18 years;
* No known musculoskeletal disorders;
* Apparently healthy
* Physically active according to American College of Sports Medicine standards and recommendations (Garber et al., 2011; RIEBE et al., 2015).

Exclusion Criteria:

* Taking any medication that could affect aerobic parameters;
* Smokers;
* Involved in an aerobic training program at the start of the study.

Primary outcomes:
measure: Maximal oxygen uptake
timeFrame: Change at Maximal oxygen uptake after two weeks
Secondary outcomes:
measure: Lactate threshold
timeFrame: Change at Lactate threshold after two weeks
measure: Muscle oxidative capacity
timeFrame: Change at Muscle oxidative capacity after two weeks
measure: Pulmonary oxygen uptake kinetics
timeFrame: Change at Pulmonary oxygen uptake kinetics after two weeks
measure: Power output achieved at the end of incremental test
timeFrame: Change at Power output achieved at the end of incremental test after two weeks
measure: Wingate anaerobic test
timeFrame: Change at Wingate anaerobic test after two weeks
measure: Time spent near VO2max
timeFrame: First to the last day of test or training, an average of 4 weeks
Other outcomes:
measure: Session-rating of perceived exertion
timeFrame: First to the last day of test or training, an average of 4 weeks
measure: Perceived Recovery Status Scale
timeFrame: First to the last day of test or training, an average of 4 weeks
measure: Heart rate
timeFrame: First to the last day of test or training, an average of 4 weeks
measure: Adipose tissue thickness
timeFrame: Change at Adipose tissue thickness after two weeks
measure: Body mass
timeFrame: Change at Body mass after two weeks
Locations:
city: Florianópolis
country: Brazil
facility: University of the State of Santa Catarina
state: Santa Catarina
Study officials:
affiliation: Member of Human Performance Research Group
name: João G Raimundo, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Buchheit M, Laursen PB. High-intensity interval training, solutions to the programming puzzle: Part I: cardiopulmonary emphasis. Sports Med. 2013 May;43(5):313-38. doi: 10.1007/s40279-013-0029-x.
citation: Laursen PB, Jenkins DG. The scientific basis for high-intensity interval training: optimising training programmes and maximising performance in highly trained endurance athletes. Sports Med. 2002;32(1):53-73. doi: 10.2165/00007256-200232010-00003.
citation: Lisboa FD, Raimundo JAG, Salvador AF, Pereira KL, Turnes T, Diefenthaeler F, Oliveira MFM, Caputo F. Acute Cardiopulmonary, Metabolic, and Neuromuscular Responses to Severe-Intensity Intermittent Exercises. J Strength Cond Res. 2019 Feb;33(2):408-416. doi: 10.1519/JSC.0000000000002130.
citation: Lisboa FD, Salvador AF, Raimundo JA, Pereira KL, de Aguiar RA, Caputo F. Decreasing Power Output Increases Aerobic Contribution During Low-Volume Severe-Intensity Intermittent Exercise. J Strength Cond Res. 2015 Sep;29(9):2434-40. doi: 10.1519/JSC.0000000000000914.
citation: Midgley AW, Mc Naughton LR. Time at or near VO2max during continuous and intermittent running. A review with special reference to considerations for the optimisation of training protocols to elicit the longest time at or near VO2max. J Sports Med Phys Fitness. 2006 Mar;46(1):1-14.
citation: Midgley AW, Mc Naughton LR, Wilkinson M. Criteria and other methodological considerations in the evaluation of time at V.O2max. J Sports Med Phys Fitness. 2006 Jun;46(2):183-8.
citation: Raimundo JAG, Turnes T, de Aguiar RA, Lisboa FD, Loch T, Ribeiro G, Caputo F. The Severe Exercise Domain Amplitude: A Comparison Between Endurance Runners and Cyclists. Res Q Exerc Sport. 2019 Mar;90(1):3-13. doi: 10.1080/02701367.2018.1549356. Epub 2019 Jan 17.
citation: Turnes T, de Aguiar RA, Cruz RS, Caputo F. Interval training in the boundaries of severe domain: effects on aerobic parameters. Eur J Appl Physiol. 2016 Jan;116(1):161-9. doi: 10.1007/s00421-015-3263-0. Epub 2015 Sep 15.