Clinical trial NCT03561818: Comparison of PR Efficiency in Home-based With Hospital-based PR in Bronchiectasis
Official title: Comparison of Pulmonary Rehabilitation Efficiency in Home-based With Hospital-based Pulmonary Rehabilitation in Bronchiectasis
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Bronchiectasis
Pulmonary Rehabilitation
Lung Diseases
Lung Diseases, Interstitial
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2018-06-19
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The investigators aimed to compare the home-based Pulmonary Rehabilitation with the hospital-based pulmonary rehabilitation in terms of pulmonary rehabilitation efficiency in patient with bronchiectasis.

Detailed description: While the benefits of pulmonary rehabilitation (PR) in cases of chronic obstructive pulmonary disease (COPD) have been well-documented, there have been only a limited number of studies investigating the efficacy of PR in patients with bronchiectasis. Some of these studies have reported positive effects of PR also in bronchiectasis patients, but have underlined the need for additional studies including larger patient groups to define PR indications, and to ensure that exercise protocols are specific for this patient group. There are many PR organizational types, such as hospital-based, telephone-mentoring with home-based or tele monitorization programs. Hospital-based supervised programs are time-consuming and costly practices. For this reason, there is a need for further studies on the effectiveness and benefits of unsupervised programs. In this study, we will compare unsupervised home-based PR and supervised hospital-based PR in terms of pulmonary rehabilitation effectiveness.

The pulmonary function tests, dyspnea perception, quality of life and exercise capacity assessments will performed before and after pulmonary rehabilitation.

Eligibility criteria: Inclusion Criteria:

* Between the ages of 18-70
* Patients signing informed consent form
* Bronchiectasis patients in the stable phase who were diagnosed with High-resolution computed tomography (HRCT).

Exclusion Criteria:

* Decompensated heart failure, uncontrolled hypertension (Systolic Blood Pressure\> 200, Diastolic Blood Pressure\> 110),
* Additional diseases that may prevent exercise,
* To be regularly exercising regularly

Primary outcomes:
measure: Changes from baseline the 6-minute walking distance at two months.
timeFrame: Two months
measure: Changes from baseline the modified Medical Research Council (mMRC) scale at two months.
timeFrame: Two months
Secondary outcomes:
measure: Changes from baseline the forced expiratory volume in one second at two months.
timeFrame: Two months
measure: Changes from baseline the peripheral muscle strength at two months.
timeFrame: Two months
measure: Changes from baseline the Quality of Life at two months.
timeFrame: Two months
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Yedikule Chest Disease Hospital
state: Zeytinburnu
Study officials:
References: