Clinical trial NCT02002013: The Fluid Translation of Research Into Practice Study
Official title: The Fluid Translation of Research Into Practice Study (Fluid-TRIPS): An International Cross-Sectional Survey of Fluid Resuscitation Practice
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Critical Care, Fluid Resuscitation
Keywords: Adult
ICU patient
Fluid resuscitation
observational study
Lead sponsor: The George Institute for Global Health, Australia
Sponsor class: OTHER
First posted: 2013-12-05
Enrollment: 2000
Sex: ALL
Minimum age (years): 16
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult patients present in the ICU on the study day

Brief summary: Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs

Detailed description: The Fluid-Translation of Research into Practice Study (TRIPS) is an international, single day, cross-sectional study planned for the second quarter of 2014, coordinated by the George Institute for Global Health, with the purpose of documenting prescribing practices for fluid resuscitation in intensive care units (ICUs) worldwide. This international cross-sectional study follows on from the publication of large-scale randomized controlled trials and meta-analyses of fluid resuscitation, which provide evidence of how fluid resuscitation may affect patient-centered outcomes.

Fluid-TRIPS is a repeat of the Saline versus Albumin for Fluid Evaluation (SAFE)-TRIPS which was an international cross-sectional survey conducted in 2007 that had 391 ICU's participate from 25 countries and provided insight into international fluid resuscitation practice at that time. Along with establishing if fluid resuscitation practices have changed since SAFE-TRIPS, Fluid-TRIPS also aims to determine the relationship between fluid choice and evidence, along with understand other factors that may influence the choice of bolus fluid in clinical practice.

Eligibility criteria: Inclusion Criteria:

Adult patients present in the ICU on the study day or admitted during the 24-hour study period will be included in the study sample.

Exclusion Criteria:

Children under 16 years are excluded

Primary outcomes:
measure: Type of resuscitation fluid in ICU
timeFrame: 24-hour study day
Secondary outcomes:
measure: Cost comparison of fluid choice between regions
timeFrame: Designated 24-hour study day
Other outcomes:
Locations:
city: Sydney
country: Australia
facility: The The George Institute for global health; Critical Care & Trauma Division
state: New South Wales
Study officials:
affiliation: The George Institute
name: Naomi Hammond
role: STUDY_CHAIR
affiliation: The George Institute
name: Colman Taylor
role: STUDY_CHAIR
References:
citation: Hammond NE, Taylor C, Finfer S, Machado FR, An Y, Billot L, Bloos F, Bozza F, Cavalcanti AB, Correa M, Du B, Hjortrup PB, Li Y, McIntryre L, Saxena M, Schortgen F, Watts NR, Myburgh J; Fluid-TRIPS and Fluidos Investigators; George Institute for Global Health, The ANZICS Clinical Trials Group, BRICNet, and the REVA research Network. Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study. PLoS One. 2017 May 12;12(5):e0176292. doi: 10.1371/journal.pone.0176292. eCollection 2017.