Clinical trial NCT06789133: Effects of Gait Training With and Without PNF on Balance ,Gait and Activities of Daily Living in Parkinson's Patients
Official title: Effects of Gait Training With and Without Proprioceptive Neuromuscular Facilitation on Balance, Gait and Activities of Daily Living in Parkinson's Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease (PD)
Proprioceptive Neuromuscular Facilitation
Keywords: PNF
PD
BWSTT
ADLs
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2025-01-23
Enrollment: 36
Sex: ALL
Minimum age (years): 45
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Proprioceptive Neuromuscular Facilitation (PNF) and gait training exercises are specifically used to treat balance, gait and functional activities in Parkinson s patients. PNF has been compared with gait training and balance training in other conditions like stroke and multiple sclerosis but limited literatures are present in which PNF has been compared with gait training in Parkinson patients.


Eligibility criteria: Inclusion Criteria:

* Parkinson's patients.
* Patients from both gender around the age of 45-65.
* Patient with a score of 42 above on the Berg Balance Scale.
* Patients with shuffling gait
* Patient with good cognitive function minimum score of 20 or more on Mini-mental Status Examination MMSE scale
* Exclusion Criteria:
* Patients with a history of CVA.
* Patient with peripheral vascular disease.
* Patient with fracture or dislocation of lower limb.
* Patient with peripheral nerve injury

Primary outcomes:
measure: Berg balance scale
timeFrame: 4 weeks
measure: Time up and go Test
timeFrame: 4 weeks
measure: Modified Barthel index
timeFrame: 4 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Arthritis and spine care , Lahore General hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Arnab Altaf, MSDPT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mazhar T, Jameel A, Sharif F, Asghar M. Effects of conventional physical therapy with and without proprioceptive neuromuscular facilitation on balance, gait, and function in patients with Parkinson's disease. J Pak Med Assoc. 2023 Jun;73(6):1280-1283. doi: 10.47391/JPMA.6710.
citation: Giardini M, Nardone A, Godi M, Guglielmetti S, Arcolin I, Pisano F, Schieppati M. Instrumental or Physical-Exercise Rehabilitation of Balance Improves Both Balance and Gait in Parkinson's Disease. Neural Plast. 2018 Mar 7;2018:5614242. doi: 10.1155/2018/5614242. eCollection 2018.
citation: Alexandre de Assis IS, Luvizutto GJ, Bruno ACM, Sande de Souza LAP. The Proprioceptive Neuromuscular Facilitation Concept in Parkinson Disease: A Systematic Review and Meta-Analysis. J Chiropr Med. 2020 Sep;19(3):181-187. doi: 10.1016/j.jcm.2020.07.003. Epub 2020 Dec 15.
citation: Mak MKY, Wong-Yu ISK. Exercise for Parkinson's disease. Int Rev Neurobiol. 2019;147:1-44. doi: 10.1016/bs.irn.2019.06.001. Epub 2019 Jun 27.
citation: Pelicioni PHS, Menant JC, Latt MD, Lord SR. Falls in Parkinson's Disease Subtypes: Risk Factors, Locations and Circumstances. Int J Environ Res Public Health. 2019 Jun 23;16(12):2216. doi: 10.3390/ijerph16122216.
citation: Mirelman A, Bonato P, Camicioli R, Ellis TD, Giladi N, Hamilton JL, Hass CJ, Hausdorff JM, Pelosin E, Almeida QJ. Gait impairments in Parkinson's disease. Lancet Neurol. 2019 Jul;18(7):697-708. doi: 10.1016/S1474-4422(19)30044-4. Epub 2019 Apr 8.
citation: Nonnekes J, Nieuwboer A. Towards Personalized Rehabilitation for Gait Impairments in Parkinson's Disease. J Parkinsons Dis. 2018;8(s1):S101-S106. doi: 10.3233/JPD-181464.