Clinical trial NCT03440749: Rhythm and Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy
Official title: Rhythm and the Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Cerebral Palsy
Keywords: rhythm
serial Reaction Time Task
Lead sponsor: University Hospital, Toulouse
Sponsor class: OTHER
Collaborators: name: Institut National de la Santé Et de la Recherche Médicale, France
First posted: 2018-02-22
Enrollment: 60
Sex: ALL
Minimum age (years): 6
Maximum age (years): 14
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Comparative monocentric physiopathological study with 2 groups of children : children with cerebral palsy and children age-matched for the control group
Primary purpose: SUPPORTIVE_CARE

Brief summary: Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them.

The child is seating in front of a computer, seating comfortably on a chair during 1 hour. The experimental task consists in learning a sequence of taps on "Serial reaction time task" type buzzers (SRTT) in which the child must press a buzzer corresponding to one of the 4 squares that on the screen. The sequence corresponds to 10 steps in a particular order.

Detailed description: Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them. In particular, the learning of movements in the presence of multisensory rhythmic information seems to have beneficial effects at the cognitive and motor level. The present study aims to test the respective effects of rhythm and multisensoriality on motor learning in children with cerebral palsy.

The motor learning task is known as the "Serial Reaction Time Task" (SRTT). It consists in repeating a sequence of movements of the upper limbs using visual-spatial information alone (V). It will test the addition of synchronous auditory stimulation to visual information or rhythmic auditory stimulation(VAR), to contrast with a control condition with non-rhythmic auditory stimulation (VANR). The performance of the children will be measured by the reaction time (RT), its stability and the number of errors made throughout the motor learning.

The child is placed in front of a screen on which 4 luminous stimuli are presented on a horizontal plane. Four buzzers are placed in front of him, each buzzer corresponds to the position of a stimulus. The stimuli light up in a predetermined sequence (10 positions) and the child must press the buzzer corresponding to the position of the stimulus that comes on. Four blocks of 5 sequences are repeated to test the general learning (B1 to B4) and then a block of random stimuli is presented to test the specific learning of the sequence (B5).

Eligibility criteria: Inclusion Criteria:

For all children:

* Age between 6 and 14 years
* Obtaining the informed consent of the person possessing parental authority for all children

For children with Cerebral Palsy:

* Diagnosis of spastic cerebral palsy of levels GMFCS I to IV
* Ability to press buzzers with the palm of the hand, Manual Ability Classification System (MASC) I to IV
* Ability to understand instructions ("tap a buzzer along with a picture or sound") (investigator's appreciation)

For control children: no pathology diagnosed

Exclusion Criteria:

For all children:

* Children with a characteristic psychiatric pathology.
* Disorders of the understanding
* Hearing deficiency
* Uncorrected visual impairment

Primary outcomes:
measure: Time reaction (TR)
timeFrame: 1 hour
Secondary outcomes:
measure: Number of errors
timeFrame: 1 hour
Other outcomes:
measure: Multisensory integration degree
timeFrame: 1 hour
measure: Degree of synchronization
timeFrame: 1 hour
Locations:
city: Toulouse
country: France
facility: University Hospital Toulouse
Study officials:
affiliation: University Hospital, Toulouse
name: Philippe Marque, MD
role: PRINCIPAL_INVESTIGATOR
References: