Clinical trial NCT03080636: Sex and Exercise-mode Differences in Post Exercise Blood Pressure and Heart Rate Variability Responses During Workday
Official title: Sex and Exercise-mode Differences in Post Exercise Blood Pressure and Heart Rate Variability Responses During Workday
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hemodynamic
Exercise
Keywords: Post-exercise hypotension
Aerobic Exercise
Resistance Exercise
Autonomic Stress
Heart Rate Variability
Sex difference
Lead sponsor: Federal University of Uberlandia
Sponsor class: OTHER
First posted: 2017-03-15
Enrollment: 20
Sex: ALL
Minimum age (years): 28
Maximum age (years): 54
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: 20 healthy adults, public servants (9W and 11M), randomly underwent three experimental sessions in early morning prior to their work routine: a circuit resistance session at 40% of 1RM, a treadmill exercise session at 60-70% of heart rate reserve and a resting control session.
Primary purpose: PREVENTION

Brief summary: The present study compared the acute effects of Sex and exercise mode on subsequent blood pressure (BP) and heart rate variability (HRV) responses during daily work in healthy adults. All subjects did 3 sessions: aerobic exercise on a treadmill, resistance exercise at the gym and a seated control session.

Detailed description: Resting blood pressure and heart rate variability are simple and non-invasive methods to evaluate cardiovascular risk after different exercise sessions. Thus, exercise can reduce these risk factors in the short and long term, but these responses can be different between sex in different exercise sessions.

Eligibility criteria: Inclusion Criteria:

* Able to practice aerobic and resistance exercise at moderate intensity;
* Men and women;
* Normotensive, pre-hypertensive or hypertensive stage 1.

Exclusion Criteria:

* Renal pathologies;
* Using beta blockers;
* History of stroke or acute myocardial infarction;
* Smokers.

Primary outcomes:
measure: Resting blood pressure
timeFrame: Change from baseline Systolic and Diastolic Blood Pressure to 15, 30, 45, 60, 210, 360 and 540 minutes after exercise/control session
measure: Heart Rate Variability
timeFrame: Change from baseline Heart Rate Variability components to 15, 30, 45 and 60 minutes after exercise/control session
Secondary outcomes:
Other outcomes:
Locations:
city: Uberlandia
country: Brazil
facility: Guilherme Morais Puga
state: Minas Gerais
Study officials:
References:
citation: Gomes Anunciacao P, Doederlein Polito M. A review on post-exercise hypotension in hypertensive individuals. Arq Bras Cardiol. 2011 May;96(5):e100-109. Epub 2011 Mar 4. English, Portuguese, Spanish.
citation: Halliwill JR, Buck TM, Lacewell AN, Romero SA. Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise? Exp Physiol. 2013 Jan;98(1):7-18. doi: 10.1113/expphysiol.2011.058065. Epub 2012 Aug 7.
citation: Queiroz AC, Rezk CC, Teixeira L, Tinucci T, Mion D, Forjaz CL. Gender influence on post-resistance exercise hypotension and hemodynamics. Int J Sports Med. 2013 Nov;34(11):939-44. doi: 10.1055/s-0033-1337948. Epub 2013 Apr 19.
citation: Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J. 1996 Mar;17(3):354-81. No abstract available.
citation: Cote AT, Bredin SS, Phillips AA, Koehle MS, Warburton DE. Greater autonomic modulation during post-exercise hypotension following high-intensity interval exercise in endurance-trained men and women. Eur J Appl Physiol. 2015 Jan;115(1):81-9. doi: 10.1007/s00421-014-2996-5. Epub 2014 Sep 11.