Clinical trial NCT05702099: Effect of Simultaneous Cystectomy on Ovarian Reserve in Cases of Adnexal Detorsion
Official title: Effect of Simultaneous Cystectomy on Ovarian Reserve in Cases of Adnexal Detorsion
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Ovarian Torsion
Keywords: ovarian torsion
cystectomy
ovarian reserve
Lead sponsor: Bagcilar Training and Research Hospital
Sponsor class: OTHER_GOV
First posted: 2023-01-27
Enrollment: 67
Sex: FEMALE
Minimum age (years): 15
Maximum age (years): 63
Standard ages: CHILD
ADULT
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All women between the ages of 15-63 who underwent emergency surgery for ovarian torsion.

Brief summary: There are mostly ovarian cysts under adnexal torsion from gynecological emergencies. There are many studies in the literature examining the effect of adnexal detorsion on ovarian reserve. However, there is no study in the literature examining the effect of concomitant cystectomy. In this study, the investigators aimed to investigate whether the cystectomy procedure performed together with detorsion has an additional effect on the ovarian reserve in cases of ovarian torsion with cysts.

Detailed description: All women who underwent emergency surgery in the investigators' obstetrics and gynecology department since April 2015 due to adnexal torsion were analyzed. All patients who underwent ovarian detorsion (Group 1) and ovarian detorsion+cystectomy (Group 2) were called for control between 6-12 months postoperatively. In all patients, the sizes of both ovaries and the number of antral follicles were counted by ultrasonography by 2 physicians who did not know the detorsion side beforehand. All women will be compared within and between groups in terms of ovarian sizes and antral follicle numbers.

Eligibility criteria: Inclusion Criteria:

* All women who underwent emergency surgery for ovarian torsion

Exclusion Criteria:

* Those who underwent oophorectomy with suspicion of malignancy
* When faced with spontaneously amputated ovary due to chronic or acute torsion
* Women with only salpinx torsion

Primary outcomes:
measure: Ovarian volume difference between groups
timeFrame: postoperative 6-12 months
measure: The number of antral follicles difference between groups
timeFrame: postoperative 6-12 months
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bagcilar Teaching and Research Hospital
state: Bagcilar
Study officials:
affiliation: Bagcilar Training and Research Hospital
name: Evrim Ebru Kovalak
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bozdag G, Demir B, Calis PT, Zengin D, Dilbaz B. The impact of adnexal torsion on antral follicle count when compared with contralateral ovary. J Minim Invasive Gynecol. 2014 Jul-Aug;21(4):632-5. doi: 10.1016/j.jmig.2014.01.007. Epub 2014 Jan 21.
citation: Calis P, Bozdag G, Karakoc Sokmensuer L, Kender N. Does ischemia-reperfusion injury affect ovarian reserve and follicle viability in a rat model with adnexal torsion? Eur J Obstet Gynecol Reprod Biol. 2015 Feb;185:126-30. doi: 10.1016/j.ejogrb.2014.12.006. Epub 2014 Dec 23.