Clinical trial NCT06692998: High and Low Level Laser Therapy in De Quervain's Tenosynovitis
Official title: Comparison of the Efficacy of High and Low Level Laser Therapy in the Treatment of De Quervain's Tenosynovitis: a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: DeQuervain Tendinopathy
Lead sponsor: Afyonkarahisar Health Sciences University
Sponsor class: OTHER
First posted: 2024-11-18
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim in this study was to compare the effects of high and low power laser treatments in the treatment of de Quervein tenosynovitis clinically and ultrasonographically.

Detailed description: De Quervain's tenosynovitis is tenosynovitis of the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons. Conservative management includes nonsteroidal anti-inflammatory drugs, wrist and thumb immobilization, ultrasound, and low-level laser therapy (LLLT). According to early literature, low-level laser therapy and ultrasound therapy appear to produce similar biological effects in reducing inflammation and promoting tissue healing.

In a study low-power laser therapy was found to be effective compared to placebo in de Quervain's tenosynovitis.

In a study of 35 female patients, low-power laser therapy (LLLT) combined with a thumb-supported splint was not superior to splint alone in patients with de Quervain's tenosynovitis.

In a more recent study low-power laser therapy was found to be similarly effective to ultrasound therapy.

The investigators found no studies in the literature on the effect of high-power laser therapy. The aim in this study was to compare the effects of high and low power laser treatments in the treatment of de Quervein tenosynovitis clinically and ultrasonographically.

Eligibility criteria: Inclusion Criteria:

* Between18-65 years of age
* Wrist pain for more than 3 weeks
* Finkelstein test positive
* Ability to understand commands

Exclusion Criteria:

* Physical therapy, injections, or surgery in the upper extremity in the last 3 months
* Fracture or trauma in the upper extremity in the last 6 months
* Radiating pain due to cervical discopathy
* Infection, loss of sensation, metal implant in the treatment area
* Inflammatory rheumatic diseases
* NSAID use
* Pregnancy or planning pregnancy during treatment
* Malignancy
* Pathology in the wrist on radiograph

Primary outcomes:
measure: Visual Pain Scale (VAS)
timeFrame: Before treatment (T0), After tratment (3. week) (T1)
measure: Ritchie Articular Index
timeFrame: Before treatment (T0), After tratment (3. week) (T1)
measure: Finkelstein test
timeFrame: Before treatment (T0), After tratment (3. week) (T1)
measure: Jamar Dynamometer
timeFrame: Before treatment (T0), After tratment (3. week) (T1)
Secondary outcomes:
measure: Disabilities of the Arm, Shoulder and Hand Questionnaire (QUICK DASH)
timeFrame: Before treatment (T0), After tratment (3. week) (T1)
measure: Ultrasonographic evaluation
timeFrame: Before treatment (T0), After tratment (3. week) (T1)
Other outcomes:
Locations:
Study officials:
affiliation: Afyonkarahisar Health Sciences University
name: SEVDA ADAR, Ass. Prof.
role: PRINCIPAL_INVESTIGATOR
References: