Clinical trial NCT05514054: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
Official title: EMBER-4: A Randomized, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE3
Conditions: Breast Neoplasms
Lead sponsor: Eli Lilly and Company
Sponsor class: INDUSTRY
First posted: 2022-08-24
Enrollment: 8000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy in participants with early breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have already taken endocrine therapy for two to five years and must have a higher-than-average risk for their cancer to return. Study participation could last up to 10 years.


Eligibility criteria: Inclusion Criteria:

* Have a diagnosis of ER+, HER2- early-stage, resected, invasive breast cancer without evidence of distant metastasis.
* Participants must have received at least 24 months but not more than 60 months of any adjuvant ET, from time of adjuvant ET initiation.
* Participants may have received (neo) adjuvant chemotherapy and/or targeted therapy with a CDK4/6- or PARP- inhibitor.
* Must have an increased risk of disease recurrence based on clinical-pathological risk features.
* Have a Performance Status of 0 or 1 on the Eastern Cooperative Oncology Group scale.
* Have adequate organ function.

Exclusion Criteria:

* Have any evidence of metastatic disease (including contralateral ALN) or inflammatory breast cancer at primary breast cancer diagnosis.
* Participants with more than a 6-month consecutive gap in therapy during the course of prior adjuvant ET.
* Participants who have completed or discontinued prior adjuvant ET \>6 months prior to screening.
* Participants with a history of previous breast cancer are excluded, with the exception of ipsilateral DCIS treated by locoregional therapy alone ≥5 years ago.
* Pregnant, breastfeeding, or expecting to conceive or father children within the projected duration of the trial, starting with the screening visit through 180 days after the last dose of study intervention.
* Participant has previously received ET of any duration for breast cancer prevention (tamoxifen or AIs) or raloxifene.
* Participants with a history of any other cancer.
* Have serious preexisting medical conditions that, in the judgment of the investigator, would preclude participation in this study.

Primary outcomes:
measure: Invasive Disease-Free Survival (IDFS)
timeFrame: Randomization to recurrence or death from any cause (up to 10 years)
Secondary outcomes:
measure: Distant Recurrence-Free Survival (DRFS)
timeFrame: Randomization to Distant Recurrence or Death from Any Cause (up to 10 Years)
measure: Overall Survival (OS)
timeFrame: Randomization to Death from Any Cause (up to 10 Years)
measure: Pharmacokinetics (PK): Steady State Plasma Concentrations of Imlunestrant
timeFrame: Year 1, Month 2 to Month 4
measure: Change from Baseline in the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (EORTC QLQ-C30) Physical Functioning
timeFrame: Visit 1 Day 1 up to end of Year 5
measure: Change from Baseline in the EORTC QLQ-C30 Role Functioning
timeFrame: Visit 1 Day 1 up to end of Year 5
measure: Change from Baseline in the EORTC QLQ-C30 Global QOL
timeFrame: Visit 1 Day 1 up to end of Year 5
measure: Proportion of Time on Study Treatment with High Overall Adverse Event Burden
timeFrame: Visit 1 Day 1 up to end of Year 5
Other outcomes:
Locations:
city: Daphne
country: United States
facility: USO - Southern Cancer Center
state: Alabama
city: Huntsville
country: United States
facility: Clearview Cancer Institute
state: Alabama
city: Mobile
country: United States
facility: Infirmary Cancer Care
state: Alabama
city: Gilbert
country: United States
facility: Banner MD Anderson Cancer Center
state: Arizona
city: Glendale
country: United States
facility: USO - Arizona Oncology Associates - HAL
state: Arizona
city: Phoenix
country: United States
facility: St. Joseph's Hospital and Medical Center
state: Arizona
city: Phoenix
country: United States
facility: Mayo Clinic in Arizona - Phoenix
state: Arizona
city: Tucson
country: United States
facility: USO - Arizona Oncology Associates - HOPE
state: Arizona
city: Tucson
country: United States
facility: The University of Arizona Cancer Center - North Campus
state: Arizona
city: Springdale
country: United States
facility: Highlands Oncology Group
state: Arkansas
city: Berkeley
country: United States
facility: UCSF - John Muir Health Cancer Center Berkeley
state: California
city: Fremont
country: United States
facility: Washington Hospital Healthcare System
state: California
city: Irvine
country: United States
facility: Chao Family Comprehensive Cancer Center and Ambulatory Care (CIACC) - Irvine
state: California
city: Loma Linda
country: United States
facility: Loma Linda University Cancer Center
state: California
city: Monterey
country: United States
facility: Pacific Cancer Care
state: California
city: Orange
country: United States
facility: St. Joseph Hospital
state: California
city: Orange
country: United States
facility: University of California, Irvine (UCI) Health - UC Irvine Medical Center
state: California
city: Sacramento
country: United States
facility: University of California Davis (UC Davis) Comprehensive Cancer Center
state: California
city: San Diego
country: United States
facility: Kaiser Permanente San Diego Mission Road
state: California
city: San Francisco
country: United States
facility: Zuckerberg San Francisco General Hospital and Trauma Center
state: California
city: San Francisco
country: United States
facility: UCSF Medical Center at Mission Bay
state: California
city: Stockton
country: United States
facility: Saint Joseph's Medical Center
state: California
city: Aurora
country: United States
facility: Anschutz Cancer Pavilion
state: Colorado
city: Colorado Springs
country: United States
facility: UCHealth Memorial Hospital
state: Colorado
city: Fort Collins
country: United States
facility: UCHealth Harmony
state: Colorado
city: Greeley
country: United States
facility: Banner MD Anderson Cancer Center at North Colorado Medical Center
state: Colorado
city: Lakewood
country: United States
facility: USO - Rocky Mountain Cancer Centers
state: Colorado
city: Loveland
country: United States
facility: Banner MD Anderson Cancer Center at McKee Medical Center
state: Colorado
city: New Haven
country: United States
facility: Yale-New Haven Hospital
state: Connecticut
city: Washington
country: United States
facility: Georgetown University Medical Center
state: District of Columbia
city: Washington
country: United States
facility: MedStar Washington Hospital Center
state: District of Columbia
city: Altamonte Springs
country: United States
facility: AdventHealth Altamonte Springs
state: Florida
city: Hollywood
country: United States
facility: Memorial Regional Hospital
state: Florida
city: Hollywood
country: United States
facility: Millennium Oncology Research Clinic
state: Florida
city: Jacksonville
country: United States
facility: Mayo Clinic in Florida
state: Florida
city: Miami
country: United States
facility: Miami Cancer Institute at Baptist Health, Inc.
state: Florida
city: Palm Bay
country: United States
facility: USO - Cancer Care Centers of Brevard
state: Florida
city: Pensacola
country: United States
facility: USO - Woodlands Medical Specialists
state: Florida
city: Plantation
country: United States
facility: Miami Cancer Institute - Plantation
state: Florida
city: Tampa
country: United States
facility: Tampa General Hospital
state: Florida
city: Atlanta
country: United States
facility: Winship Cancer Institute, Emory University
state: Georgia
city: Atlanta
country: United States
facility: Northside Hospital
state: Georgia
city: Savannah
country: United States
facility: Summit Cancer Care, PC
state: Georgia
city: Honolulu
country: United States
facility: Kaiser Permanente Moanalua Medical Center
state: Hawaii
city: Honolulu
country: United States
facility: Kapiolani Medical Center for Women and Children
state: Hawaii
city: Chicago
country: United States
facility: Northwestern Memorial Hospital
state: Illinois
city: Chicago
country: United States
facility: University of Illinois at Chicago
state: Illinois
city: Peoria
country: United States
facility: Illinois Cancer Care
state: Illinois
city: Springfield
country: United States
facility: Simmons Cancer Institute at SIU
state: Illinois
city: Westwood
country: United States
facility: The University of Kansas Cancer Center - Westwood
state: Kansas
city: Covington
country: United States
facility: Ochsner Clinic Foundation
state: Louisiana
city: Hammond
country: United States
facility: Pontchartrain Cancer Center
state: Louisiana
city: New Orleans
country: United States
facility: Ochsner Clinic Foundation
state: Louisiana
city: Lewiston
country: United States
facility: Central Maine Medical Center
state: Maine
city: York
country: United States
facility: York Hospital
state: Maine
city: Bethesda
country: United States
facility: Walter Reed National Military Medical Center
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
city: Boston
country: United States
facility: Dana-Farber Cancer Institute
state: Massachusetts
city: Danvers
country: United States
facility: Mass General/North Shore Cancer Center
state: Massachusetts
city: Fairhaven
country: United States
facility: Southcoast Centers for Cancer Care
state: Massachusetts
city: Foxboro
country: United States
facility: Dana-Farber Cancer Institute - Foxborough
state: Massachusetts
city: Methuen
country: United States
facility: Dana-Farber Cancer Institute - Merrimack Valley
state: Massachusetts
city: Milford
country: United States
facility: Dana-Farber/Brigham and Women's Cancer Center at Milford Regional Medical Center
state: Massachusetts
city: Newton
country: United States
facility: Mass General Cancer Center at Newton-Wellesley
state: Massachusetts
city: South Weymouth
country: United States
facility: Dana-Farber/Brigham and Women's Cancer Center - South Shore Hospital
state: Massachusetts
city: Worcester
country: United States
facility: University of Massachusetts Medical School
state: Massachusetts
city: Edina
country: United States
facility: M Health Fairview Cancer Clinic -Edina
state: Minnesota
city: Minneapolis
country: United States
facility: USO - Minnesota Oncology Hematology
state: Minnesota
city: Minneapolis
country: United States
facility: Allina Health Cancer Institute
state: Minnesota
city: Rochester
country: United States
facility: Mayo Clinic in Rochester, Minnesota
state: Minnesota
city: Columbia
country: United States
facility: University of Missouri Hospital
state: Missouri
city: Saint Louis
country: United States
facility: Washington University
state: Missouri
city: Omaha
country: United States
facility: Nebraska Methodist Hospital
state: Nebraska
city: Lebanon
country: United States
facility: Dartmouth-Hitchcock Medical Center
state: New Hampshire
city: Londonderry
country: United States
facility: Dana-Farber - New Hampshire Oncology/Hematology
state: New Hampshire
city: Camden
country: United States
facility: MD Anderson Cancer Center at Cooper
state: New Jersey
city: East Brunswick
country: United States
facility: Astera Cancer Care
state: New Jersey
city: Little Silver
country: United States
facility: Regional Cancer Care Associates
state: New Jersey
city: New Brunswick
country: United States
facility: Rutgers Cancer Institute of New Jersey
state: New Jersey
city: Pennington
country: United States
facility: Capital Health Medical Center - Hopewell
state: New Jersey
city: Albuquerque
country: United States
facility: New Mexico Oncology Hematology Consultants Ltd.
state: New Mexico
city: Albuquerque
country: United States
facility: University of New Mexico Comprehensive Cancer Center
state: New Mexico
city: Albany
country: United States
facility: USO - New York Oncology Hematology
state: New York
city: Brooklyn
country: United States
facility: Maimonides Cancer Center
state: New York
city: Brooklyn
country: United States
facility: NYU Langone Health - Brooklyn
state: New York
city: Lake Success
country: United States
facility: R.J. Zuckerberg Cancer Center
state: New York
city: Mineola
country: United States
facility: Perlmutter Cancer Center at NYU Langone Hospital - Long Island
state: New York
city: Mount Kisco
country: United States
facility: Northern Westchester Hospital
state: New York
city: New York
country: United States
facility: Laura and Isaac Perlmutter Cancer Center
state: New York
city: New York
country: United States
facility: NYC Health + Hospitals / Bellevue
state: New York
city: New York
country: United States
facility: Memorial Sloan Kettering Cancer Center
state: New York
city: Queens
country: United States
facility: Queens Medical Associates
state: New York
city: Rochester
country: United States
facility: University of Rochester - Wilmot Cancer Institute
state: New York
city: Sleepy Hollow
country: United States
facility: Phelps Hospital
state: New York
city: Staten Island
country: United States
facility: Staten Island University Hospital
state: New York
city: Westbury
country: United States
facility: Clinical Research Alliance
state: New York
city: Asheville
country: United States
facility: Messino Cancer Center
state: North Carolina
city: Canton
country: United States
facility: Aultman Hospital
state: Ohio
city: Cincinnati
country: United States
facility: The Christ Hospital Cancer Center
state: Ohio
city: Cincinnati
country: United States
facility: USO - Oncology Hematology Care
state: Ohio
city: Columbus
country: United States
facility: The Mark H Zangmeister Center
state: Ohio
city: Toledo
country: United States
facility: Mercy Health - St. Vincent Medical Center
state: Ohio
city: Youngstown
country: United States
facility: St. Elizabeth Youngstown Hospital
state: Ohio
city: Corvallis
country: United States
facility: Good Samaritan Regional Medical Center
state: Oregon
city: Eugene
country: United States
facility: USO - Oncology Associates of Oregon
state: Oregon
city: Portland
country: United States
facility: Oregon Health and Science University
state: Oregon
city: Tigard
country: United States
facility: USO - Compass Oncology
state: Oregon
city: Bethlehem
country: United States
facility: St. Luke's University Health Network
state: Pennsylvania
city: Horsham
country: United States
facility: USO - Alliance Cancer Specialists, PC
state: Pennsylvania
city: Philadelphia
country: United States
facility: Thomas Jefferson University - Clinical Research Institute
state: Pennsylvania
city: Philadelphia
country: United States
facility: Thomas Jefferson University, Aria Jefferson Health
state: Pennsylvania
city: Willow Grove
country: United States
facility: Asplundh Cancer Pavilion
state: Pennsylvania
city: Providence
country: United States
facility: Lifespan Cancer Institute
state: Rhode Island
city: Greenville
country: United States
facility: St Francis Cancer Center
state: South Carolina
city: Germantown
country: United States
facility: The West Clinic, PLLC dba West Cancer Center
state: Tennessee
city: Knoxville
country: United States
facility: University of Tennessee Medical Center
state: Tennessee
city: Nashville
country: United States
facility: Sarah Cannon Research Institute
state: Tennessee
city: Austin
country: United States
facility: USO - Texas Oncology
state: Texas
city: Dallas
country: United States
facility: USO - Texas Oncology
state: Texas
city: Dallas
country: United States
facility: USO - Texas Oncology
state: Texas
city: Denison
country: United States
facility: USO - Texas Oncology
state: Texas
city: El Paso
country: United States
facility: Texas Oncology - West Texas
state: Texas
city: El Paso
country: United States
facility: William Beaumont Army Medical Center
state: Texas
city: Flower Mound
country: United States
facility: USO - Texas Oncology
state: Texas
city: Fort Sam Houston
country: United States
facility: Brooke Army Medical Center
state: Texas
city: Fort Worth
country: United States
facility: John Peter Smith Hospital
state: Texas
city: Fort Worth
country: United States
facility: The Center for Cancer and Blood Disorders
state: Texas
city: Fort Worth
country: United States
facility: USO - Texas Oncology
state: Texas
city: Fredericksburg
country: United States
facility: USO - Texas Oncology
state: Texas
city: McAllen
country: United States
facility: USO - Texas Oncology
state: Texas
city: Plano
country: United States
facility: USO - Texas Oncology
state: Texas
city: Round Rock
country: United States
facility: Scott & White Hospital - Round Rock
state: Texas
city: San Antonio
country: United States
facility: Mays Cancer Center
state: Texas
city: Temple
country: United States
facility: Baylor Scott & White Medical Center - Temple
state: Texas
city: The Woodlands
country: United States
facility: US Oncology Research Network
state: Texas
city: Webster
country: United States
facility: USO - Texas Oncology
state: Texas
city: Charlottesville
country: United States
facility: University of Virginia Health System
state: Virginia
city: Fairfax
country: United States
facility: Inova Schar Cancer Institute
state: Virginia
city: Fort Belvoir
country: United States
facility: Fort Belvoir Community Hospital
state: Virginia
city: Midlothian
country: United States
facility: Bon Secours St. Francis Medical Center
state: Virginia
city: Norfolk
country: United States
facility: USO - Virginia Oncology Associates
state: Virginia
city: Reston
country: United States
facility: USO - Virginia Cancer Specialists
state: Virginia
city: Roanoke
country: United States
facility: USO - Oncology & Hematology Associates of Southwest Virginia
state: Virginia
city: Berazategui
country: Argentina
facility: Centro de Oncología e Investigación de Buenos Aires
state: Buenos Aires
city: Ciudad Autónoma de Buenos Aires
country: Argentina
facility: Instituto Alexander Fleming
state: Buenos Aires
city: Mar del Plata
country: Argentina
facility: Instituto de Investigaciones Clínicas Mar del Plata
state: Buenos Aires
city: San Nicolas
country: Argentina
facility: Go Centro Medico San Nicolás
state: Buenos Aires
city: Buenos Aires
country: Argentina
facility: CIPREC
state: Ciudad Autónoma De Buenos Aires
city: Buenos Aires
country: Argentina
facility: Mautalen Salud e Investigación
state: Ciudad Autónoma De Buenos Aires
city: Caba
country: Argentina
facility: Fundación Cenit Para La Investigación En Neurociencias
state: Ciudad Autónoma De Buenos Aires
city: Caba
country: Argentina
facility: Clinica Adventista Belgrano
state: Ciudad Autónoma De Buenos Aires
city: Capital
country: Argentina
facility: Centro Medico Privado CEMAIC
state: Córdoba
city: Río Cuarto
country: Argentina
facility: Instituto Médico Río Cuarto
state: Córdoba
city: Viedma
country: Argentina
facility: Clinica Viedma S. A
state: Río Negro
city: Rosario
country: Argentina
facility: Fundacion Estudios Clinicos
state: Santa Fe
city: San Miguel de Tucumán
country: Argentina
facility: Centro Medico San Roque
state: Tucumán
city: Buenos Aires
country: Argentina
facility: Investigaciones Clinicas Moleculares (ICM)
city: Buenos Aires
country: Argentina
facility: Centro Oncologico Korben
city: Buenos Aires
country: Argentina
facility: Fundación Respirar
city: La Rioja
country: Argentina
facility: Fundación CORI para la Investigación y Prevención del Cáncer
city: Mendoza
country: Argentina
facility: Fundacion Scherbovsky
city: San Juan
country: Argentina
facility: Centro Polivalente de Asistencia e Investigacion Clinica - CER San Juan
city: San Juan
country: Argentina
facility: Instituto San Marcos
city: Coffs Harbour
country: Australia
facility: Coffs Harbour Health Campus
state: New South Wales
city: Darlinghurst
country: Australia
facility: St Vincent's Hospital
state: New South Wales
city: Gosford
country: Australia
facility: Gosford Hospital
state: New South Wales
city: Liverpool
country: Australia
facility: Liverpool Hospital
state: New South Wales
city: Newcastle
country: Australia
facility: Lake Macquarie Private Hospital
state: New South Wales
city: Sydney
country: Australia
facility: Mater Hospital Sydney
state: New South Wales
city: Tiwi
country: Australia
facility: Royal Darwin Hospital
state: Northern Territory
city: Mackay
country: Australia
facility: Mackay Base Hospital
state: Queensland
city: Southport
country: Australia
facility: Gold Coast University Hospital
state: Queensland
city: Townsville
country: Australia
facility: The Townsville Hospital
state: Queensland
city: Urraween
country: Australia
facility: Hervey Bay Hospital
state: Queensland
city: Woodville
country: Australia
facility: The Queen Elizabeth Hospital
state: South Australia
city: Hobart
country: Australia
facility: Royal Hobart Hospital
state: Tasmania
city: Launceston
country: Australia
facility: Launceston General Hospital
state: Tasmania
city: Ballarat Central
country: Australia
facility: Ballarat Health Services
state: Victoria
city: Box Hill
country: Australia
facility: Box Hill Hospital
state: Victoria
city: Clayton
country: Australia
facility: Monash Health
state: Victoria
city: Geelong
country: Australia
facility: Barwon Health
state: Victoria
city: Melbourne
country: Australia
facility: St Vincent's Hospital
state: Victoria
city: Melbourne
country: Australia
facility: Northern Hospital
state: Victoria
city: Melbourne
country: Australia
facility: Maroondah Hospital
state: Victoria
city: Shepparton
country: Australia
facility: Goulburn Valley Health
state: Victoria
city: Nedlands
country: Australia
facility: Breast Cancer Research Centre-WA
state: Western Australia
city: Graz
country: Austria
facility: Medizinische Universität Graz
state: Steiermark
city: Schwaz
country: Austria
facility: Private Practice - Dr. Hubalek
state: Tirol
city: Vienna
country: Austria
facility: Universitaetsklinikum Allgemeines Krankenhaus Wien
state: Wien
city: Vienna
country: Austria
facility: Klinik Hietzing
state: Wien
city: Salzburg
country: Austria
facility: Uniklinikum Salzburg
city: Wien
country: Austria
facility: Medizinische Universität Wien
city: Anderlecht
country: Belgium
facility: Institut Jules Bordet
state: Bruxelles-Capitale, Région De
city: Auderghem
country: Belgium
facility: CHIREC - site delta
state: Bruxelles-Capitale, Région De
city: Brussels
country: Belgium
facility: CHU Saint-Pierre
state: Bruxelles-Capitale, Région De
city: Brussels
country: Belgium
facility: Centre Hospitalier Universitaire Brugmann
state: Bruxelles-Capitale, Région De
city: Brussels
country: Belgium
facility: Cliniques universitaires Saint-Luc
state: Bruxelles-Capitale, Région De
city: Charleroi
country: Belgium
facility: Grand Hôpital de Charleroi
state: Hainaut
city: La Louvière
country: Belgium
facility: Groupe Jolimont
state: Hainaut
city: Hasselt
country: Belgium
facility: Jessa Ziekenhuis
state: Limburg
city: Sint-Niklaas
country: Belgium
facility: AZ Nikolaas
state: Oost-Vlaanderen
city: Leuven
country: Belgium
facility: UZ Leuven
state: Vlaams-Brabant
city: Kortrijk
country: Belgium
facility: AZ Groeninge Campus Kennedylaan
state: West-Vlaanderen
city: Oostende
country: Belgium
facility: AZ Oostende vzw
state: West-Vlaanderen
city: Ieper
country: Belgium
facility: Jan Yperman ziekenhuis
city: Liège
country: Belgium
facility: Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman
city: Namur
country: Belgium
facility: CHU UCL Namur/Site Sainte Elisabeth
city: Ottignies
country: Belgium
facility: Clinique Saint Pierre
city: Verviers
country: Belgium
facility: CHR Verviers - La Tourelle
city: Salvador
country: Brazil
facility: Nucleo de Oncologia da Bahia
state: Bahia
city: Fortaleza
country: Brazil
facility: Centro de Pesquisa Clínica do Instituto do Câncer do Ceará
state: Ceará
city: Vitória
country: Brazil
facility: CEDOES
state: Espírito Santo
city: Goiânia
country: Brazil
facility: Hospital Araújo Jorge
state: Goiás
city: Belo Horizonte
country: Brazil
facility: Oncocentro de Minas Gerais
state: Minas Gerais
city: Curitiba
country: Brazil
facility: Centro Integrado de Oncologia de Curitiba
state: Paraná
city: Londrina
country: Brazil
facility: Hospital de Cancer de Londrina
state: Paraná
city: Belem
country: Brazil
facility: CTO - Centro de Tratamento Oncológico
state: Pará
city: Recife
country: Brazil
facility: Multihemo
state: Pernambuco
city: Ijui
country: Brazil
facility: ONCOSITE - Centro de Pesquisa Clinica em Oncologia
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Hospital Moinhos de Vento
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Hospital São Lucas da PUCRS
state: Rio Grande Do Sul
city: Porto Velho
country: Brazil
facility: Hospital de Amor Amazônia
state: Rondônia
city: Barretos
country: Brazil
facility: Fundação Pio XII - Hospital de Câncer de Barretos
state: São Paulo
city: Ribeirão Preto
country: Brazil
facility: Hospital de Clínicas de Ribeirão Preto
state: São Paulo
city: Santo André
country: Brazil
facility: Faculdade de Medicina do ABC
state: São Paulo
city: Sao Paulo
country: Brazil
facility: Hospital Sírio Libanês
state: São Paulo
city: Sao Paulo
country: Brazil
facility: Hospital BP
state: São Paulo
city: Sao Paulo
country: Brazil
facility: A. C. Camargo Cancer Center
state: São Paulo
city: Sao Paulo
country: Brazil
facility: Instituto D'Or de Pesquisa e Ensino (IDOR)
state: São Paulo
city: Sao Paulo
country: Brazil
facility: Hospital Santa Paula
state: São Paulo
city: São José do Rio Preto
country: Brazil
facility: Fundação Faculdade Regional de Medicina de São José do Rio Preto
state: São Paulo
city: Brasilia
country: Brazil
facility: Hospital Sirio Libanes
city: Rio de Janeiro
country: Brazil
facility: Instituto Nacional de Câncer - INCA
city: Rio de Janeiro
country: Brazil
facility: Hospital São Lucas de Copacabana
city: Rio de Janeiro
country: Brazil
facility: Centro de Tratamento de Tumores Botafogo para Oncoclinicas Rio de Janeiro SA
city: Rio de Janeiro
country: Brazil
facility: Instituto de Educação, Pesquisa e Gestão em Saúde
city: São Paulo
country: Brazil
facility: IPITEC
city: São Paulo
country: Brazil
facility: NotreDame Intermedica Saude S.A
city: São Paulo
country: Brazil
facility: Instituto de Ensino e Pesquisa São Lucas
city: São Paulo
country: Brazil
facility: Icesp - Instituto Do Câncer Do Estado de São Paulo
city: São Paulo
country: Brazil
facility: Clínica de Pesquisa e Centro de Estudos em Ginecologia Oncológica e Mamária LTDA
city: São Paulo
country: Brazil
facility: Hospital Alemao Oswaldo Cruz
city: São Paulo
country: Brazil
facility: Núcleo de Pesquisa Clínica da Rede São Camilo
city: São Paulo
country: Brazil
facility: Instituto de Assistência Médica ao Servidor Público Estadual - IAMSPE/HSPE-FMO Conhecer Centro de Oncolog -T
city: Calgary
country: Canada
facility: Arthur J.E. Child Comprehensive Cancer Centre
state: Alberta
city: Surrey
country: Canada
facility: BC Cancer Surrey
state: British Columbia
city: London
country: Canada
facility: Victoria Hospital & Children's Hospital - London Health Sciences Centre
state: Ontario
city: Toronto
country: Canada
facility: Humber River Hospital
state: Ontario
city: Toronto
country: Canada
facility: Sunnybrook Research Institute - Odette Cancer Centre
state: Ontario
city: Montreal
country: Canada
facility: Jewish General Hospital
state: Quebec
city: Montreal
country: Canada
facility: Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de-Montréal (CIUSSS NÎM) - H -T
state: Quebec
city: Montréal
country: Canada
facility: Centre Hospitalier de l'Université de Montréal
state: Quebec
city: Quebec City
country: Canada
facility: CHU de Québec-Université Laval, Hôpital du Saint-Sacrement
state: Quebec
city: Wuhu Shi
country: China
facility: Wannan Medical College Yijishan Hospital
state: Anhui
city: Beijing
country: China
facility: Beijing Hospital
state: Beijing
city: Beijing
country: China
facility: Cancer Hospital Chinese Academy of Medical Science
state: Beijing
city: Beijing
country: China
facility: Peking University People's Hospital
state: Beijing
city: Beijing
country: China
facility: Beijing Friendship Hospital Affiliate of Capital University
state: Beijing
city: Fuzhou
country: China
facility: Fujian Medical University Union Hospital-1 Bingfanglou
state: Fujian
city: Fuzhou
country: China
facility: The 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army
state: Fujian
city: Dongguan
country: China
facility: Dongguan People's Hospital
state: Guangdong
city: Foshan
country: China
facility: Shunde Hospital of Southern Medical Univesity
state: Guangdong
city: Guangzhou
country: China
facility: Sun Yat-sen University Cancer Center
state: Guangdong
city: Guangzhou
country: China
facility: Guangdong Maternity and Child Health Care Hospital
state: Guangdong
city: Huizhou
country: China
facility: Huizhou Municipal Central Hospital
state: Guangdong
city: Jiangmen
country: China
facility: Jiangmen Center Hospital
state: Guangdong
city: Shantou
country: China
facility: Cancer Hospital of Shantou University Medical College
state: Guangdong
city: Shenzhen
country: China
facility: ShenZhen People's Hospital
state: Guangdong
city: Shenzhen
country: China
facility: Shenzhen Second People's Hospital
state: Guangdong
city: Shenzhen
country: China
facility: Cancer Hospital Chinese Academy of Medical Sciences. Shenzhen Center
state: Guangdong
city: Zhanjiang
country: China
facility: Central Hospital of Guangdong Provincial Agricutural Reclamation
state: Guangdong
city: Haikou
country: China
facility: Hainan General Hospital
state: Hainan
city: Baoding
country: China
facility: Affiliated Hospital of Hebei University
state: Hebei
city: Anyang
country: China
facility: Anyang Cancer Hospital
state: Henan
city: Luoyang
country: China
facility: The First Affiliated Hospital of Henan University of Science &Technology
state: Henan
city: Wuhan
country: China
facility: Union Hospital Tongji Medical College Huazhong University of Science and Technology
state: Hubei
city: Wuhan
country: China
facility: Renmin Hospital of Wuhan University
state: Hubei
city: Wuhan
country: China
facility: Hubei Cancer Hospital
state: Hubei
city: Xiangyang
country: China
facility: Xiangyang Central Hospital
state: Hubei
city: Changde
country: China
facility: The First People's Hospital of Changde City
state: Hunan
city: Changsha
country: China
facility: Xiangya Hospital Central South University
state: Hunan
city: Changsha
country: China
facility: Hunan Cancer Hospital
state: Hunan
city: Yongzhou
country: China
facility: The Central Hospital of Yongzhou - North Campus
state: Hunan
city: Yueyang
country: China
facility: The First People's Hospital of Yueyang
state: Hunan
city: Huai'an
country: China
facility: First Huai'an Hospital Affiliated to Nanjing Medical University
state: Jiangsu
city: Nanjing
country: China
facility: Jiangsu Province Hospital
state: Jiangsu
city: Suzhou
country: China
facility: The First Affiliated Hospital of Soochow University
state: Jiangsu
city: Nanchang
country: China
facility: The Third Hospital of Nanchang
state: Jiangxi
city: Changchun
country: China
facility: The First Hospital of Jilin University
state: Jilin
city: Xi'an
country: China
facility: The First Affiliated Hospital of Xi'an Jiaotong University
state: Shaanxi
city: Jinan
country: China
facility: Jinan Central Hospital
state: Shandong
city: Jining
country: China
facility: Jining Medical University - Affiliated Hospital
state: Shandong
city: Shanghai
country: China
facility: Fudan University Shanghai Cancer Center
state: Shanghai
city: Yuncheng Shi
country: China
facility: Yuncheng Central Hospital - Eastern Hospital
state: Shanxi
city: Chengdu
country: China
facility: Sichuan Cancer hospital
state: Sichuan
city: Deyang
country: China
facility: Deyang City People's Hospital
state: Sichuan
city: Neijiang
country: China
facility: The Second People's Hospital of Neijiang
state: Sichuan
city: Tianjing
country: China
facility: Tianjin Medical University Cancer Institute & Hospital
state: Tianjin
city: Urumqi
country: China
facility: Xinjiang Medical University Cancer Hospital - Urumqi
state: Xinjiang
city: Hangzhou
country: China
facility: The First People's Hospital of Hangzhou
state: Zhejiang
city: Hangzhou
country: China
facility: Zhejiang Provincial People's Hospital
state: Zhejiang
city: Hangzhou
country: China
facility: Zhejiang Cancer Hospital
state: Zhejiang
city: Ningbo
country: China
facility: Hwa Mei Hospital University of Chinese Academy of Sciences
state: Zhejiang
city: Ningbo
country: China
facility: Ningbo First Hospital
state: Zhejiang
city: Horovice
country: Czechia
facility: Nemocnice Horovice
state: Beroun
city: Brno
country: Czechia
facility: Masarykuv onkologicky ustav
state: Brno-město
city: Hradec Kralove
country: Czechia
facility: Fakultni nemocnice Hradec Kralove
state: Hradec Králové
city: Ostrava
country: Czechia
facility: Fakultni nemocnice Ostrava
state: Moravskoslezský Kraj
city: Pardubice
country: Czechia
facility: Multiscan
state: Pardubický Kraj
city: Prague
country: Czechia
facility: Fakultni Thomayerova nemocnice
state: Praha 4
city: Praha
country: Czechia
facility: Fakultni nemocnice Motol
state: Praha 5
city: Prague
country: Czechia
facility: Fakultni nemocnice Bulovka
state: Praha 8
city: Bordeaux
country: France
facility: Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest
state: Aquitaine
city: La Chaussée-Saint-Victor
country: France
facility: Polyclinique De Blois
state: Centre
city: La Rochelle
country: France
facility: Groupe Hospitalier La Rochelle-Ré-Aunis - Hôpital Saint Louis
state: Charente-Maritime
city: Besançon
country: France
facility: CHU Besançon
state: Doubs
city: Brest
country: France
facility: CHRU de Brest
state: Finistère
city: Limoges
country: France
facility: Clinique Francois Chenieux
state: Haute-Vienne
city: Saint-Cloud
country: France
facility: Institut Curie - site Saint-Cloud
state: Hauts-de-Seine
city: La Tronche
country: France
facility: Chu Grenoble Alpes
state: Isère
city: Mont-de-Marsan
country: France
facility: Centre Hospitalier Intercommunal de Mont-de-Marsan et du Pays des Sources
state: Landes
city: Montpellier
country: France
facility: Centre de Cancérologie du Grand Montpellier
state: Languedoc-Roussillon
city: Saint Herblain
country: France
facility: Institut de Cancérologie de l'Ouest
state: Loire-Atlantique
city: Vandoeuvre-lès-Nancy
country: France
facility: Institut de Cancérologie de Lorraine Alexis Vautrin
state: Lorraine
city: Reims
country: France
facility: Institut Jean Godinot
state: Marne
city: Nancy
country: France
facility: Polyclinique de Gentilly
state: Meurthe-et-Moselle
city: Metz
country: France
facility: Centre Hospitalier Régional Metz Thionville - Hôpital de Mercy
state: Moselle
city: Le Mans
country: France
facility: Clinique Victor Hugo Le Mans
state: Pays-de-la-Loire
city: Bayonne
country: France
facility: Centre Hospitalier de la Côte Basque
state: Pyrénées-Atlantiques
city: Pau
country: France
facility: Centre Hospitalier de Pau
state: Pyrénées-Atlantiques
city: Perpignan
country: France
facility: Centre Catalan d'Oncologie
state: Pyrénées-Orientales
city: Lyon
country: France
facility: Hopital Prive Jean Mermoz
state: Rhône-Alpes
city: Avignon
country: France
facility: Sainte Catherine Institut du Cancer Avignon Provence
state: Vaucluse
city: La Roche-sur-Yon
country: France
facility: CHD Vendee
state: Vendée
city: Poitiers
country: France
facility: Centre Hospitalier Universitaire de Poitiers
state: Vienne
city: Clermont-Ferrand
country: France
facility: Pole Santé République
city: Nice
country: France
facility: Centre Antoine-Lacassagne
city: Paris
country: France
facility: Hôpital Saint-Louis
city: Paris
country: France
facility: Hôpital Européen Georges Pompidou
city: Paris
country: France
facility: Groupe Hospitalier Diaconesses Croix Saint Simon
city: Paris
country: France
facility: Institut Curie
city: Paris
country: France
facility: Hôpital Tenon
city: Saint-Grégoire
country: France
facility: Centre Hospitalier Privé Saint-Grégoire
city: Valenciennes
country: France
facility: Centre de cancérologie des Dentellières
city: Créteil
country: France
facility: Henri Mondor Hospital
state: Île-de-France
city: Paris
country: France
facility: Groupe hospitalier Paris saint Joseph
state: Île-de-France
city: Freiburg im Breisgau
country: Germany
facility: Universitaetsklinikum Freiburg
state: Baden-Württemberg
city: Friedrichshafen
country: Germany
facility: Private Practice - Dr. Helmut Oettle und Prof.Dr.med. Frank Mayer
state: Baden-Württemberg
city: Mannheim
country: Germany
facility: Universitätsmedizin Mannheim
state: Baden-Württemberg
city: Stuttgart
country: Germany
facility: Robert-Bosch-Krankenhaus
state: Baden-Württemberg
city: Tübingen
country: Germany
facility: Universitaetsklinikum Tuebingen
state: Baden-Württemberg
city: Ulm
country: Germany
facility: Universitaetsklinikum Ulm
state: Baden-Württemberg
city: Augsburg
country: Germany
facility: Gemeinschaftspraxis hop-augsburg
state: Bayern
city: Augsburg
country: Germany
facility: Universitaetsklinikum Augsburg
state: Bayern
city: Donauwörth
country: Germany
facility: Onkologiezentrum Donauwörth
state: Bayern
city: Erlangen
country: Germany
facility: Universitaetsklinikum Erlangen
state: Bayern
city: Kempten
country: Germany
facility: Klinikverbund Allgäu gGmbH
state: Bayern
city: München
country: Germany
facility: Klinikum der Ludwig-Maximilians-Universitaet Muenchen
state: Bayern
city: Potsdam
country: Germany
facility: Klinikum Ernst von Bergmann
state: Brandenburg
city: Frankfurt
country: Germany
facility: Agaplesion Markus Krankenhaus
state: Hessen
city: Wiesbaden
country: Germany
facility: Helios HSK Wiesbaden
state: Hessen
city: Schwerin
country: Germany
facility: HELIOS Kliniken Schwerin
state: Mecklenburg-Vorpommern
city: Bottrop
country: Germany
facility: Marienhospital Bottrop
state: Nordrhein-Westfalen
city: Dortmund
country: Germany
facility: St.-Johannes-Hospital Dortmund
state: Nordrhein-Westfalen
city: Düsseldorf
country: Germany
facility: MVZ Medical Center Düsseldorf GmbH
state: Nordrhein-Westfalen
city: Essen
country: Germany
facility: Kliniken Essen-Mitte, Evangelische Huyssens-Stiftung
state: Nordrhein-Westfalen
city: Herne
country: Germany
facility: St. Anna Hospital
state: Nordrhein-Westfalen
city: Krefeld
country: Germany
facility: Zentrum fuer ambulante gynaekologische Onkologie (ZAGO)
state: Nordrhein-Westfalen
city: Köln
country: Germany
facility: Universitaetsklinikum Koeln
state: Nordrhein-Westfalen
city: Mayen
country: Germany
facility: Onkologisch-hämatologisches Forschungsinstitut am Habsburgring
state: Rheinland-Pfalz
city: Trier
country: Germany
facility: Klinikum Mutterhaus der Borromäerinnen
state: Rheinland-Pfalz
city: Homburg
country: Germany
facility: Universitaetsklinikum des Saarlandes
state: Saarland
city: Dessau
country: Germany
facility: Städtisches Klinikum Dessau
state: Sachsen-Anhalt
city: Kiel
country: Germany
facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel
state: Schleswig-Holstein
city: Gera
country: Germany
facility: SRH Wald-Klinikum Gera
state: Thüringen
city: Suhl
country: Germany
facility: SRH Zentralklinikum Suhl
state: Thüringen
city: Berlin
country: Germany
facility: Praxisklinik Krebsheilkunde fur Frauen
city: Berlin
country: Germany
facility: Onkologische Schwerpunktpraxis Kurfuerstendamm
city: Berlin
country: Germany
facility: Helios Klinikum Berlin-Buch
city: Goettingen
country: Germany
facility: OSP Göttingen
city: Patras
country: Greece
facility: Olympion General Clinic
state: Achaḯa
city: Patras
country: Greece
facility: University Hospital of Patras
state: Achaḯa
city: Athens
country: Greece
facility: Iaso Private General Obstetrics Gynecological & Pediatric Clinic Diagnostic Therapeutic & Research Center -T
state: Attikí (Region)
city: Athens
country: Greece
facility: Agios Savvas Regional Cancer Hospital
state: Attikí
city: Athens
country: Greece
facility: Alexandra Hospital
state: Attikí
city: Athens
country: Greece
facility: IASO Obstetrics - Gynecology Clinic
state: Attikí
city: Chaidari
country: Greece
facility: Attikon General University Hospital
state: Attikí
city: Nea Kifissia
country: Greece
facility: General Oncology Hospital of Kifissia "Agioi Anargiroi"
state: Attikí
city: Ioannina
country: Greece
facility: University Hospital of Ioannina
state: Ioánnina
city: Heraklion
country: Greece
facility: University General Hospital of Heraklion
state: Irakleío
city: Thessaloniki
country: Greece
facility: BioClinic Thessaloniki
state: Kentrikí Makedonía
city: Thessaloniki
country: Greece
facility: Agios Loukas Clinic
state: Kentrikí Makedonía
city: Thessaloniki
country: Greece
facility: Euromedica General Clinic of Thessaloniki
state: Thessaloníki
city: Thessaloniki
country: Greece
facility: European Interbalkan Medical Center
state: Thessaloníki
city: Larissa
country: Greece
facility: University General Hospital of Larissa
state: Thessalía
city: Hksar
country: Hong Kong
facility: Queen Mary Hospital
city: Kecskemét
country: Hungary
facility: Bacs-Kiskun Megyei Korhaz
state: Bács-Kiskun
city: Nyiregyhaza
country: Hungary
facility: Szabolcs Szatmár Bereg Vármegyei Oktatókórház
state: Szabolcs-Szatmár-Bereg
city: Budapest
country: Hungary
facility: Országos Onkológiai Intézet
city: Budapest
country: Hungary
facility: Uzsoki Utcai Kórház
city: Debrecen
country: Hungary
facility: Debreceni Egyetem Klinikai Kozpont
city: Visakhapatnam
country: India
facility: Mahatma Gandhi Cancer Hospital and Research Institute
state: Andhra Pradesh
city: New Delhi
country: India
facility: Delhi State Cancer Institute
state: Delhi
city: Ahmedabad
country: India
facility: Hemato Oncology Clinic
state: Gujarat
city: Ahmedabad
country: India
facility: KD Hospital
state: Gujarat
city: Bangalore
country: India
facility: Medstar Speciality Hospital
state: Karnataka
city: Belagavi
country: India
facility: KLES Dr. Prabhakar Kore Hospital & M.R.C
state: Karnataka
city: Thiruvananthapuram
country: India
facility: Regional Cancer Centre - Thiruvananthapuram
state: Kerala
city: Karad
country: India
facility: Krishna Institute of Medical Sciences - Karad
state: Maharashtra
city: Kolhapur
country: India
facility: Kolhapur Cancer Centre Private Limited
state: Maharashtra
city: Mumbai
country: India
facility: Tata Memorial Hospital
state: Maharashtra
city: Nagpur
country: India
facility: Rashtrasant Tukdoji Regional Cancer Hospital
state: Maharashtra
city: Pune
country: India
facility: Grant Medical Foundation - Ruby Hall Clinic
state: Maharashtra
city: Pune
country: India
facility: Lifepoint Multispeciality Hospital
state: Maharashtra
city: Bhubaneswar
country: India
facility: All India Institute of Medical Sciences
state: Odisha
city: Chennai
country: India
facility: Cancer Institute (WIA)
state: Tamil Nadu
city: Hyderabad
country: India
facility: Nizam's Institute of Medical Sciences
state: Telangana
city: Kanpur
country: India
facility: Regency Hospital
state: Uttar Pradesh
city: Chandigarh
country: India
facility: Postgraduate Institute of Medical Education & Research
city: Galway
country: Ireland
facility: Galway University Hospital
state: Connaught
city: Cork
country: Ireland
facility: Bon Secours Cork Hospital
city: Cork
country: Ireland
facility: Cork University Hospital
city: Dublin
country: Ireland
facility: St. Vincent's University Hospital
city: Dublin
country: Ireland
facility: St. James's Hospital
city: Dublin
country: Ireland
facility: UCD School of Medicine Beacon Hospital
city: Dublin
country: Ireland
facility: Beaumont Hospital, Dublin
city: Sligo
country: Ireland
facility: Sligo General Hospital
city: Waterford
country: Ireland
facility: Waterford Regional Hospital
city: Kfar Saba
country: Israel
facility: Meir Medical Center
state: HaMerkaz
city: Petah Tikva
country: Israel
facility: Rabin Medical Center
state: HaMerkaz
city: Ramat Gan
country: Israel
facility: Sheba Medical Center
state: HaMerkaz
city: Zerifin
country: Israel
facility: Yitzhak Shamir Medical Center
state: HaMerkaz
city: Tel Aviv
country: Israel
facility: Sourasky Medical Center
state: Tell Abīb
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center
state: Yerushalayim
city: Jerusalem
country: Israel
facility: Hadassah Medical Center
state: Yerushalayim
city: Haifa
country: Israel
facility: Carmel Hospital
state: Ḥeifā
city: Naples
country: Italy
facility: University of Naples Federico II
state: Campania
city: Napoli
country: Italy
facility: Istituto Nazionale Tumori IRCCS Fondazione Pascale
state: Campania
city: Misterbianco
country: Italy
facility: Humanitas Istituto Clinico Catanese
state: Catania
city: Bologna
country: Italy
facility: IRCCS - AOU di Bologna
state: Emilia-Romagna
city: Genova
country: Italy
facility: Ospedale San Martino
state: Liguria
city: Monza
country: Italy
facility: Ospedale San Gerardo-ASST Monza
state: Lombardia
city: Rozzano
country: Italy
facility: Humanitas
state: Milano
city: Rome
country: Italy
facility: Istituto Nazionale Tumori Regina Elena
state: Roma
city: Statte
country: Italy
facility: Ospedale San Giovanni Moscati
state: Taranto
city: Candiolo
country: Italy
facility: Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia
state: Torino
city: Firenze
country: Italy
facility: Azienda Ospedaliera Universitaria Careggi
state: Toscana
city: Ancona
country: Italy
facility: Aou Ospedali Riuniti Umberto I
city: Bergamo
country: Italy
facility: Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII
city: Brindisi
country: Italy
facility: Ospedale Antonio Perrino
city: Macerata
country: Italy
facility: Ospedale Generale Provinciale Macerata
city: Milano
country: Italy
facility: Istituto Europeo di Oncologia IRCCS
city: Modena
country: Italy
facility: Azienda Ospedaliero Universitaria
city: Padova
country: Italy
facility: Istituto Oncologico Veneto IRCCS
city: Parma
country: Italy
facility: Azienda Ospedaliero Universitaria di Parma
city: Terni
country: Italy
facility: Azienda Ospedaliera Santa Maria Terni
city: Nagoya
country: Japan
facility: Nagoya University Hospital
state: Aichi
city: Nagoya
country: Japan
facility: Nagoya City University Hospital
state: Aichi
city: Chiba-shi
country: Japan
facility: Chiba cancer center
state: Chiba
city: Kamogawa
country: Japan
facility: Kameda Clinic
state: Chiba
city: Matsuyama
country: Japan
facility: National Hospital Organization Shikoku Cancer Center
state: Ehime
city: Otashi
country: Japan
facility: Gunma Prefectural Cancer Center
state: Gunma
city: Takasaki
country: Japan
facility: National Hospital Organization Takasaki General Medical Centar
state: Gunma
city: Fukuyama
country: Japan
facility: Fukuyama City Hospital
state: Hiroshima
city: Sapporo
country: Japan
facility: National Hospital Organization Hokkaido Cancer Center
state: Hokkaido
city: Sapporo
country: Japan
facility: Hokkaido University Hospital
state: Hokkaido
city: Nishinomiya
country: Japan
facility: Hyogo Medical University Hospital
state: Hyogo
city: Tsukuba
country: Japan
facility: Tsukuba University Hospital
state: Ibaraki
city: Kanazawa
country: Japan
facility: Ishikawa Prefectural Central Hospital
state: Ishikawa
city: Uchinada
country: Japan
facility: Kanazawa Medical University Hospital
state: Ishikawa
city: Yahaba-cho, Shiwa-gun
country: Japan
facility: Iwate Medical University Hospital
state: Iwate
city: Kawasaki
country: Japan
facility: St. Marianna University Hospital
state: Kanagawa
city: Sagamihara
country: Japan
facility: Kitasato University Hospital
state: Kanagawa
city: Yokohama
country: Japan
facility: Yokohama City University Medical Center
state: Kanagawa
city: Yokohama
country: Japan
facility: Kanagawa cancer center
state: Kanagawa
city: Sendai-shi
country: Japan
facility: Tohoku University Hospital
state: Miyagi
city: Matsumoto
country: Japan
facility: Shinshu University Hospital
state: Nagano
city: Niigata-shi
country: Japan
facility: Niigata Cancer Center Hospital
state: Niigata
city: Naha
country: Japan
facility: Naha Nishi Clinic
state: Okinawa
city: Hirakata
country: Japan
facility: Kansai Medical University Hospital
state: Osaka
city: Izumo
country: Japan
facility: Shimane University Hospital
state: Shimane
city: Utsunomiya
country: Japan
facility: Tochigi Cancer Center
state: Tochigi
city: Bunkyo-ku
country: Japan
facility: Juntendo University Hospital
state: Tokyo
city: Chuo-ku
country: Japan
facility: St. Luke's International Hospital
state: Tokyo
city: Hachioji-shi
country: Japan
facility: Tokai University Hachioji Hospital
state: Tokyo
city: Koto
country: Japan
facility: Japanese Foundation for Cancer Research
state: Tokyo
city: Shinagawa
country: Japan
facility: Showa University Hospital
state: Tokyo
city: Shinjyuku-ku
country: Japan
facility: National Center for Global Health and Medicine
state: Tokyo
city: Chiba
country: Japan
facility: Chiba University Hospital
city: Fukuoka
country: Japan
facility: National Hospital Organization Kyushu Cancer Center
city: Fukushima
country: Japan
facility: Fukushima Medical University
city: Gifu
country: Japan
facility: Gifu University Hospital
city: Hiroshima
country: Japan
facility: Hiroshima City Hospital
city: Hiroshima
country: Japan
facility: Hiroshima University Hospital
city: Kagoshima
country: Japan
facility: Sagara Hospital
city: Kumamoto
country: Japan
facility: Kumamoto Breast Surgical Hospital
city: Kumamoto
country: Japan
facility: Kumamoto Shinto General Hospital
city: Kyoto
country: Japan
facility: University Hospital,Kyoto Prefectural University of Medicine
city: Kyoto
country: Japan
facility: Kyoto University Hospital
city: Miyazaki
country: Japan
facility: Miyazaki Prefectural Miyazaki Hospital
city: Okayama
country: Japan
facility: Okayama University Hospital
city: Okinawa
country: Japan
facility: Nakagami Hospital Okinawa
city: Osaka
country: Japan
facility: National Hospital Organization - Osaka National Hospital - Institute For Clinical Research
city: Saitama
country: Japan
facility: Saitama Red Cross Hospital
city: Shizuoka
country: Japan
facility: Shizuoka General Hospital
city: Tokushima
country: Japan
facility: Tokushima University Hospital
city: Cheongju-si
country: Korea, Republic of
facility: Chungbuk National University Hospital
state: Chungcheongbuk-do [Chungbuk]
city: Cheonan-si
country: Korea, Republic of
facility: Soon Chun Hyang University Cheonan Hospital
state: Chungcheongnam-do [Chungnam]
city: Incheon
country: Korea, Republic of
facility: Inha University Hospital
state: Incheon-gwangyeoksi [Incheon]
city: Namdong-gu
country: Korea, Republic of
facility: Gachon University Gil Medical Center
state: Incheon-gwangyeoksi [Incheon]
city: Hwasun-gun
country: Korea, Republic of
facility: Chonnam National University Hwasun Hospital
state: Jeonranamdo
city: Goyang-si
country: Korea, Republic of
facility: National Cancer Center
state: Kyǒnggi-do
city: Seongnam-si
country: Korea, Republic of
facility: CHA Bundang Medical Center, CHA University
state: Kyǒnggi-do
city: Seongnam
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
state: Kyǒnggi-do
city: Suwon-si
country: Korea, Republic of
facility: Ajou University Hospital
state: Kyǒnggi-do
city: Gyeongsan-si
country: Korea, Republic of
facility: Yeungnam Univeristy Medical Center
state: Kyǒngsangbuk-do
city: Busan
country: Korea, Republic of
facility: Dongnam Institute of Radiological and Medical Sciences
state: Pusan-Kwangyǒkshi
city: Seoul
country: Korea, Republic of
facility: Korea University Anam Hospital
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: Severance Hospital, Yonsei University Health System
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: Gangnam Severance Hospital
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: The Catholic Univ. of Korea Seoul St. Mary's Hospital
state: Seoul-teukbyeolsi [Seoul]
city: Seoul
country: Korea, Republic of
facility: Korea University Guro Hospital
state: Seoul-teukbyeolsi [Seoul]
city: Daegu
country: Korea, Republic of
facility: Kyungpook National University Chilgok Hospital
state: Taegu-Kwangyǒkshi
city: Ulsan
country: Korea, Republic of
facility: Ulsan University Hospital
state: Ulsan-Kwangyǒkshi
city: Tijuana
country: Mexico
facility: Hospital Angeles
state: Baja California
city: Tuxtla Gutierrez
country: Mexico
facility: Centro de Estudios Y Prevencion Del Cancer
state: Chiapas
city: Mexico City
country: Mexico
facility: CENEIT Oncológicos. Centro Especializado en Investigación y Tratamientos Oncológicos
state: Distrito Federal
city: Mexico City
country: Mexico
facility: Grupo Medico Camino Sc
state: Distrito Federal
city: León
country: Mexico
facility: Preparaciones Oncologicas
state: Guanajuato
city: Guadalajara
country: Mexico
facility: CIO - Centro de Inmuno-Oncología de Occidente
state: Jalisco
city: Guadalajara
country: Mexico
facility: Clinica de Investigacion en Reumatologia y Obesidad S. C.
state: Jalisco
city: Monterrey
country: Mexico
facility: Axis Heilsa S. de R.L. de C.V.
state: Nuevo León
city: Monterrey
country: Mexico
facility: Centro Regiomontano de Investigación
state: Nuevo León
city: Monterrey
country: Mexico
facility: Filios Alta Medicina
state: Nuevo León
city: San Pedro Garza Garcia
country: Mexico
facility: Centro Medico Zambrano Hellion
state: Nuevo León
city: San Luis Potosi
country: Mexico
facility: Oncologico Potosino, S.C.
state: San Luis Potosí
city: Ciudad Madero
country: Mexico
facility: Centro de Estudios de Investigacion Metabolicos y Cardiovasculares
state: Tamaulipas
city: Chihuahua
country: Mexico
facility: Scientia Investigacion Clinica S.C.
city: Oaxaca
country: Mexico
facility: Oaxaca Site Management Organization
city: Oaxaca
country: Mexico
facility: Centro de Investigacion Clinica de Oaxaca
city: Puebla
country: Mexico
facility: Unidad Médica Onco-hematológica
city: Querétaro
country: Mexico
facility: PanAmerican Clinical Research - Querétaro - Avenida Antea
city: Toluca
country: Mexico
facility: Centro Oncologico Estatal ISSEMyM ( COEI )
city: Assen
country: Netherlands
facility: Wilhelmina Ziekenhuis Assen
state: Drenthe
city: Maastricht
country: Netherlands
facility: Maastricht UMC+
state: Limburg
city: Venlo
country: Netherlands
facility: VieCuri Medisch Centrum, locatie Venlo
state: Limburg
city: Breda
country: Netherlands
facility: Amphia Ziekenhuis, locatie Breda Molengracht
state: Noord-Brabant
city: Hoofddorp
country: Netherlands
facility: Spaarne Gasthuis - Hoofddorp
state: Noord-Holland
city: Zaandam
country: Netherlands
facility: Zaans Medisch Centrum
state: Noord-Holland
city: Deventer
country: Netherlands
facility: Deventer Ziekenhuis
state: Overijssel
city: Hengelo
country: Netherlands
facility: Ziekenhuisgroep Twente, locatie Almelo
state: Overijssel
city: Delft
country: Netherlands
facility: Reinier de Graaf Ziekenhuis, locatie Delft
state: Zuid-Holland
city: Den Haag
country: Netherlands
facility: Haga Ziekenhuis locatie Leyweg
state: Zuid-Holland
city: Dordrecht
country: Netherlands
facility: Albert Schweitzer Ziekenhuis, locatie Dordwijk
state: Zuid-Holland
city: Torun
country: Poland
facility: MICS Centrum Medyczne Torun
state: Kujawsko-pomorskie
city: Siedlce
country: Poland
facility: Mazowiecki Szpital Wojewódzki w Siedlcach
state: Mazowieckie
city: Warszawa
country: Poland
facility: Luxmed Onkologia sp. z o. o.
state: Mazowieckie
city: Warszawa
country: Poland
facility: Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie
state: Mazowieckie
city: Oswiecim
country: Poland
facility: FORMED2
state: Małopolskie
city: Opole
country: Poland
facility: Opolskie Centrum Onkologii w Opolu im. prof. Tadeusza Koszarowskiego
state: Opolskie
city: Gdynia
country: Poland
facility: Szpitale Pomorskie Sp. z o. o.
state: Pomorskie
city: Koszalin
country: Poland
facility: Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie
state: Zachodniopomorskie
city: Lodz
country: Poland
facility: Salve Medica
state: Łódzkie
city: Lisbon
country: Portugal
facility: Champalimaud Foundation
state: Lisboa
city: Lisbon
country: Portugal
facility: Centro Hospitalar Universitário Lisboa Norte, E.P.E. - Hospital de Santa Maria
state: Lisboa
city: Vila Nova de Gaia
country: Portugal
facility: Centro Hospitalar de Vila Nova de Gaia/Espinho - Unidade I
state: Porto
city: Almada
country: Portugal
facility: Hopital Garcia de Orta
state: Setúbal
city: Lisboa
country: Portugal
facility: Hospital da Luz Lisboa
city: Lisboa
country: Portugal
facility: Hospital Beatriz Ângelo
city: Brasov
country: Romania
facility: C.M.D.T.A. Neomed
state: Brașov
city: Bucharest
country: Romania
facility: Onco Medint Srl
state: București
city: Bucharest
country: Romania
facility: Lotus-Med
state: București
city: Bucharest
country: Romania
facility: SC Memorial Healthcare International SRL
state: București
city: Cluj-Napoca
country: Romania
facility: Institutul Oncologic Cluj
state: Cluj
city: Ovidiu
country: Romania
facility: Ovidius Clinical Hospital OCH
state: Constanța
city: Craiova
country: Romania
facility: Centrul de Oncologie "Sfântul Nectarie"
state: Dolj
city: Otopeni
country: Romania
facility: Radiology Therapeutic Center
state: Ilfov
city: Timișoara
country: Romania
facility: S C Oncocenter Oncologie Clinica S R L
state: Timiș
city: București
country: Romania
facility: Spitalul Clinic Colțea
city: București
country: Romania
facility: Gral Medical Diagnostic Center
city: Singapore
country: Singapore
facility: National Cancer Centre Singapore
state: Central Singapore
city: Singapore
country: Singapore
facility: Raffles Hospital
state: Central Singapore
city: Bratislava
country: Slovakia
facility: Onkologicky Ustav sv. Alzbety
state: Bratislavský Kraj
city: Bratislava
country: Slovakia
facility: Narodny onkologicky ustav
state: Bratislavský Kraj
city: A Coruña
country: Spain
facility: CHUAC-Hospital Teresa Herrera
state: A Coruña [La Coruña]
city: Almeria
country: Spain
facility: Hospital Universitario Torrecárdenas
state: Andalucía
city: Mahon
country: Spain
facility: Hospital Mateu Orfila
state: Balears [Baleares]
city: Palma
country: Spain
facility: Hospital Universitari Son Espases
state: Balears [Baleares]
city: Barcelona
country: Spain
facility: Parc de Salut Mar - Hospital del Mar
state: Barcelona [Barcelona]
city: Barcelona
country: Spain
facility: Hospital Quiron Barcelona
state: Barcelona [Barcelona]
city: Barcelona
country: Spain
facility: Hospital Universitari Vall d'Hebron
state: Barcelona [Barcelona]
city: Sant Cugat del Vallès
country: Spain
facility: Hospital Universitari General de Catalunya
state: Barcelona [Barcelona]
city: Barcelona
country: Spain
facility: Hospital Universitari Dexeus
state: Catalunya [Cataluña]
city: Barcelona
country: Spain
facility: Hospital Clínic de Barcelona
state: Catalunya [Cataluña]
city: Barcelona
country: Spain
facility: Hospital de la Santa Creu i Sant Pau
state: Catalunya [Cataluña]
city: Cáceres
country: Spain
facility: Hospital San Pedro de Alcántara
state: Extremadura
city: Jaen
country: Spain
facility: Complejo Hospitalario de Jaén
state: Jaén
city: Logroño
country: Spain
facility: Hospital San Pedro
state: La Rioja
city: Lleida
country: Spain
facility: Hospital Universitario Arnau de Vilanova de Lleida
state: Lleida [Lérida]
city: Lugo
country: Spain
facility: Hospital Lucus Augusti
state: Lugo [Lugo]
city: Getafe
country: Spain
facility: Hospital Universitario Getafe
state: Madrid, Comunidad De
city: Madrid
country: Spain
facility: Hospital General Universitario Gregorio Marañon
state: Madrid, Comunidad De
city: Madrid
country: Spain
facility: Hospital Universitario Infanta Leonor
state: Madrid, Comunidad De
city: Madrid
country: Spain
facility: Hospital Universitario Ramón y Cajal
state: Madrid, Comunidad De
city: Madrid
country: Spain
facility: Hospital Universitario 12 de Octubre
state: Madrid, Comunidad De
city: Madrid
country: Spain
facility: Hospital Universitario La Paz
state: Madrid, Comunidad De
city: El Palmar, Murcia
country: Spain
facility: Hospital Clínico Universitario Virgen de la Arrixaca
state: Murcia, Región De
city: Malaga
country: Spain
facility: H.R.U Málaga - Hospital Materno-infantil
state: Málaga
city: Pamplona
country: Spain
facility: Complejo Hospitalario de Navarra
state: Navarra
city: Bilbao
country: Spain
facility: Osi Bilbao-Basurto
state: País Vasco
city: La Laguna
country: Spain
facility: Hospital Universitario de Canarias
state: Santa Cruz De Tenerife
city: Reus
country: Spain
facility: Hospital Universitari Sant Joan de Reus
state: Tarragona [Tarragona]
city: Valencia
country: Spain
facility: Hospital Clinico de Valencia
state: Valenciana, Comunitat
city: Valencia
country: Spain
facility: Hospital Quirónsalud Valencia
state: València
city: Alicante
country: Spain
facility: Hospital General Universitario de Alicante
city: Badajoz
country: Spain
facility: Hospital Infanta Cristina
city: Burgos
country: Spain
facility: Hospital Universitario de Burgos
city: Granada
country: Spain
facility: Hospital Universitario San Cecilio
city: Madrid
country: Spain
facility: Hospital La Princesa
city: Madrid
country: Spain
facility: Hospital Beata María Ana
city: Madrid
country: Spain
facility: Hospital Ruber Internacional
city: Madrid
country: Spain
facility: Hospital Clinico San Carlos
city: Málaga
country: Spain
facility: Hospital Vithas Málaga
city: Santa Cruz de Tenerife
country: Spain
facility: Hospital Universitario Nuestra Señora de Candelaria
city: Segovia
country: Spain
facility: Hospital General de Segovia
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Macarena
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Del Rocio
city: Toledo
country: Spain
facility: Hospital Universitario de Toledo
city: Valladolid
country: Spain
facility: Hospital Clínico Universitario de Valladolid
city: Zaragoza
country: Spain
facility: Hospital Clínico Universitario Lozano Blesa
city: Changhua County
country: Taiwan
facility: Changhua Christian Hospital
state: Changhua
city: Tainan City
country: Taiwan
facility: Chi Mei Hospital - Liouying Branch
state: Tainan
city: Kaohsiung
country: Taiwan
facility: Kaohsiung Medical University Chung-Ho Memorial Hospital
city: New Taipei City
country: Taiwan
facility: Taipei Tzu Chi General Hospital
city: Taichung
country: Taiwan
facility: Taichung Veterans General Hospital
city: Tainan
country: Taiwan
facility: National Cheng Kung University Hospital
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital
city: Taipei
country: Taiwan
facility: Mackay Memorial Hospital
city: Taipei
country: Taiwan
facility: Taipei Veterans General Hospital
city: Taipei
country: Taiwan
facility: Koo Foundation Sun Yat-Sen Cancer Center
city: Taoyuan
country: Taiwan
facility: Chang Gung Medical Foundation-Linkou Branch
city: Altindağ
country: Turkey
facility: Hacettepe Universitesi
state: Ankara
city: Istanbul, Pendik
country: Turkey
facility: Marmara Universitesi Pendik Egitim Arastirma Hastanesi
state: İstanbul
city: Stanbul
country: Turkey
facility: Medipol Mega Universite Hastanesi
state: İstanbul
city: Izmir, Karsiyaka
country: Turkey
facility: Izmir Medical Park Hospital
state: İzmir
city: Mugla
country: Turkey
facility: Mugla Sitki Kocman Universitesi Egitim ve Arastirma Hastanesi
state: Muğla
city: Adapazarı
country: Turkey
facility: Sakarya Training and Research Hospital
state: Sakarya
city: Adana
country: Turkey
facility: Adana Medical Park Seyhan Hastanesi
city: Adana
country: Turkey
facility: Adana City Hospital
city: Ankara
country: Turkey
facility: Ankara Gülhane Eitim ve Aratrma Hastanesi
city: Ankara
country: Turkey
facility: Ankara Etlik City Hospital
city: Ankara
country: Turkey
facility: Memorial Ankara Hastanesi
city: Ankara
country: Turkey
facility: Ankara Bilkent Şehir Hastanesi
city: Antalya
country: Turkey
facility: Akdeniz Universitesi Hastanesi
city: Antalya
country: Turkey
facility: Antalya Egitim ve Arastırma Hastanesi
city: Bursa
country: Turkey
facility: Uludag Universitesi
city: Diyarbakir
country: Turkey
facility: Dicle Üniversitesi
city: Edirne
country: Turkey
facility: Trakya University Medical Faculty Hospital
city: Gaziantep
country: Turkey
facility: Gaziantep Universitesi Sahinbey Arastirma ve Uygulama Hastanesi
city: Istanbul
country: Turkey
facility: TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi
city: Izmir
country: Turkey
facility: Ege Universitesi Hastanesi
city: Izmir
country: Turkey
facility: zmir Katip Çelebi Üniversitesi Atatürk Eitim Ve Aratrma Hastanesi
city: Kocaeli
country: Turkey
facility: Kocaeli Üniversitesi
city: Malatya
country: Turkey
facility: İnönü Üniversitesi Turgut Özal Tıp Merkezi Eğitim ve Araştırma Hastanesi
city: Mersin
country: Turkey
facility: Mersin University
city: Samsun
country: Turkey
facility: Ondokuz Mayıs Universitesi
city: Plymouth
country: United Kingdom
facility: Derriford Hospital
state: Devon
city: Preston
country: United Kingdom
facility: Panthera Biopartners - Preston
state: England
city: Colchester
country: United Kingdom
facility: Colchester General Hospital
state: Essex
city: East Kilbride, Glasgow
country: United Kingdom
facility: Hairmyres Hospital
state: Great Britain
city: Northwood
country: United Kingdom
facility: Mount Vernon Hospital
state: Hertfordshire
city: Stevenage
country: United Kingdom
facility: Lister Hospital
state: Hertfordshire
city: London
country: United Kingdom
facility: St Bartholomew's Hospital
state: London, City Of
city: Rochdale
country: United Kingdom
facility: Panthera Biopartners - Manchester
state: Manchester
city: Wigan
country: United Kingdom
facility: Oncology Research
state: Manchester
city: Edinburgh
country: United Kingdom
facility: Western General Hospital
state: Midlothian
city: Liverpool
country: United Kingdom
facility: Clatterbridge Cancer Centre - Liverpool
city: Manchester
country: United Kingdom
facility: The Christie NHS Foundation Trust
city: Reading
country: United Kingdom
facility: Royal Berkshire Hospital
Study officials:
affiliation: Eli Lilly and Company
name: Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
role: STUDY_DIRECTOR
References: