Clinical trial NCT03440541: Uses of Gamma Irradiated Amniotic Membrane as an Alternative Method in Psoriasis Treatment
Official title: Uses of Gamma Irradiated Amniotic Membrane as an Alternative Method in Psoriasis Treatment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Psoriasis
Keywords: Amniotic membrane
Psoriasis
Treatment
Lead sponsor: Egyptian Atomic Energy Authority
Sponsor class: OTHER_GOV
First posted: 2018-02-22
Enrollment: 22
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Using of human amniotic membrane extra-cellular matrix as a topical treatment for improving Psoriasis Area and Severity Index (PASI).

Detailed description: Human amniotic membrane extra-cellular matrix was purchased from National center for radiation research and technology, Egypt, under commercial name REGE pro gel.

Eligibility criteria: Inclusion Criteria:

* patients have psoriasis lesion

Exclusion Criteria:

* must stop other line of treatment

Primary outcomes:
measure: Scaling size decrement
timeFrame: 2 weeks
measure: Histopathological improvement
timeFrame: 6 weeks
Secondary outcomes:
measure: Erythema disappearing
timeFrame: 4-6 weeks
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Amniotic tissue lab
Study officials:
affiliation: NATIONAL CENTER FOR RADIATION RESEARCH AND TECHNOLOGY
name: Nashwa K Radwan, PhD
role: STUDY_DIRECTOR
References:
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