Clinical trial NCT06766877: Effect of Core Stability Versus Conventional Exercise for Functional Ambulation of Calf Muscle
Official title: Effect of Core Stability Versus Conventional Exercise for Functional Ambulation of Calf Muscle
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: knee
arthritis
tendon
Lead sponsor: Dow University of Health Sciences
Sponsor class: OTHER
First posted: 2025-01-09
Enrollment: 100
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Knee osteoarthritis (KOA) is a degenerative joint disease causing pain, stiffness, and reduced quality of life. While treatments often focus on drugs or surgery, noninvasive exercises like core stabilization and ankle/foot strengthening show potential but lack comparative studies. Understanding anatomical factors like Achilles tendon (AT) thickness is crucial for targeted rehabilitation, though measurement reliability remains an issue. This study aims to compare the effects of these exercises on KOA symptoms and evaluate the use of digital calipers for AT thickness measurement, aiming to enhance clinical management of KOA.

Detailed description: The objective of the study is:

1. To determine the interrater and intrarater reliability of digital calliper to measure the side to side Achilles tendon thickness.
2. To determine the impact of 24 sessions of core stability translated in gait ambulation.
3. determines the relationships between Achilles tendon thickness (ATT), knee symptoms/functions, and foot alignment in knee OA patients, considering their interconnected biomechanical nature.
4. compare the effects of core stability and ankle-foot strengthening exercises on clinical outcomes in KOA patients

Eligibility criteria: Inclusion Criteria:

* 40 years old, had been diagnosed with KOA based on ACR, and

  * having Grade II or III osteoarthritis by K/L criteria.

Exclusion Criteria:

* post-traumatic osteoarthritis
* lower limb sensorimotor dysfunction,
* Any history of knee fracture/ tumor/ infection and hip/knee surgery.
* Total Knee Replacement patients.
* Neurological disease.
* Patient received physical therapy treatment from last 6 months.
* Inflammatory Arthritis (Rheumatoid Arthritis)
* Use of any intra-articular injections (steroid/ hyaluronic acid/ PRP.) from last 3-6 months.

Primary outcomes:
measure: Knee Injury and Osteoarthritis Outcome Score (KOOS) Questionnaire
timeFrame: 8 weeks
measure: Visual Analogue Scale (VAS) at rest
timeFrame: 8 weeks
measure: Stair climb test
timeFrame: 8 weeks
measure: Knee flexion range of motion
timeFrame: 8 weeks
measure: knee extension range of motion
timeFrame: 8 weeks
measure: Achilles tendon thickness
timeFrame: 8 weeks
measure: 30 second chair test
timeFrame: 8 weeks
measure: Timed up and go test
timeFrame: 8 weeks
measure: 40 meter walk test
timeFrame: 8 weeks
measure: Gastrocnemius muscle strength
timeFrame: 8 weeks
measure: navicular/foot ratio
timeFrame: 8 weeks
measure: Ankle range of motion
timeFrame: 8 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: BIPTRM
state: Sindh
Study officials:
affiliation: Dow University of Health Sciences/ Baqai Medical University
name: SHAIKH NABI BUKHSH NAZIR, PhD Scholar
role: PRINCIPAL_INVESTIGATOR
References: