Clinical trial NCT02515318: Physiotherapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Official title: Effects of a Physiotherapy Program in Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: COPD
Keywords: COPD
Exacerbation
Hospitalisation
Physiotherapy
Lead sponsor: Universidad de Granada
Sponsor class: OTHER
First posted: 2015-08-04
Enrollment: 60
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Chronic Obstructive Pulmonary Disease (COPD) is projected to be the fifth leading burden of disease worldwide by the year 2020. An acute exacerbation of COPD (AECOPD) is defined as an acute event characterized by a worsening of the patient's respiratory symptoms that requires a modification in the medication. AECOPD are frequent (mean of 1-4 exacerbations each year). It increases in frequency with the severity of the disease. The objective of this study is to examine whether a physical therapy intervention can reduce impairment in patients with COPD during hospitalization due to an acute exacerbation.

Detailed description: Chronic obstructive pulmonary disease (COPD) is one of the leading diseases causing mortality and morbidity, despite advanced pharmacotherapy and therapeutic management.

COPD patients suffer frequent exacerbations, defined as 'acute events characterized by a worsening of the patient's respiratory symptoms that is beyond normal day-to-day variations and leads to a change in medication'. Acute illness and prolonged bed rest are associated with loss of muscle mass and a significant decline in functional ability and mobility. Interventions to counteract these impairments are indicated.

Eligibility criteria: Inclusion Criteria:

* COPD diagnosis with exacerbation.
* No contraindication of physiotherapy.
* Signed written consent.
* Medical approval for inclusion

Exclusion Criteria:

* Neurological, orthopedic or heart diseases.
* Prosthetic devices in the lower limbs.

Primary outcomes:
measure: Muscle strength
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
measure: Exercise capacity
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
Secondary outcomes:
measure: Respiratory function
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
measure: Dyspnea
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
measure: Health status
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
measure: Fatigue
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
measure: Impact of COPD
timeFrame: Participants will be followed for the duration of hospital stay, an expected average of 9 days.
Other outcomes:
measure: Dependency levels
timeFrame: Baseline
measure: Comorbidities
timeFrame: Baseline
Locations:
city: Granada
country: Spain
facility: University of Granada
city: Granada
country: Spain
facility: Department of Physical Therapy
Study officials:
affiliation: Universidad de Granada
name: Marie Carmen Valenza, PhD
role: PRINCIPAL_INVESTIGATOR
References: