Clinical trial NCT06396351: Factors Affecting Abdominal Compliance During CO2 Insufflation in Laparoscopic Abdominal Surgery
Official title: Factors Influencing Abdominal Compliance During CO2 Insufflation in Patients Undergoing Laparoscopic Abdominal Surgery
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Laparoscopic Surgery
Keywords: abdominal compliance
intraabdominal pressure
laparoscopic surgery
Lead sponsor: Ankara University
Sponsor class: OTHER
First posted: 2024-05-02
Enrollment: 90
Sex: ALL
Minimum age (years): 18
Maximum age (years): 82
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: ASA I-III patients aged between 18 and 82 years undergoing elective abdominal surgery with laparoscopic technique.

Brief summary: The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.

Detailed description: During laparoscopic surgery, pneumoperitoneum is achieved by insufflating carbon dioxide (CO2) gas into the abdominal cavity to create a safe working space. Pneumoperitoneum-induced elevation in intra-abdominal pressure (IAP) can result in various complications. Abdominal compliance (AC), represents the slope of the P-V curve of the abdominal cavity and is a measure of the ease of abdominal dilatation, is important to balance between surgical safety and complications. The aim of this study was to determine the effect of demographic and anatomic variables on AC.

The study included 90 patients who underwent laparoscopic abdominal surgery. Subcutaneous adipose tissue and abdominal muscle thickness were measured ultrasonographically. Mean AC was calculated during insufflation using the formula (ΔV/ΔP). The relationship between demographic and anatomic variables and AC was investigated

Eligibility criteria: Inclusion Criteria:

Aged between 18 and 82 years ASA class I-III Elective abdominal surgery with laparoscopic technique

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Exclusion Criteria:

Aged below 18 and above 82 ASA IV-V

Primary outcomes:
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary outcomes:
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
measure: The factors affecting abdominal compliance
timeFrame: From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Ankara University Medical School Anesthesiology and ICU Department
Study officials:
affiliation: Ankara University
name: Menekse Ozcelik
role: STUDY_CHAIR
affiliation: Ankara University
name: Ezgi Yıldırım
role: PRINCIPAL_INVESTIGATOR
affiliation: Ankara University
name: Keziban Sanem Çakar Turhan
role: STUDY_CHAIR
affiliation: Ankara University
name: Aysegul Guven
role: PRINCIPAL_INVESTIGATOR
affiliation: Ankara University
name: Derya Gökmen
role: PRINCIPAL_INVESTIGATOR
References: