Clinical trial NCT06405659: Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis
Official title: Immediate Fever During Anaesthesia Recovery After Surgical Procedure With Scoliosis: A Case Report and Literature Review
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Fever
Scoliosis
Surgical Trauma
Hypothermia
General Anaesthesia
Lead sponsor: Affiliated Hospital of Guangdong Medical University
Sponsor class: OTHER
First posted: 2024-05-08
Enrollment: 1
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: A 15-year-old female with a 1-year history of scoliosis was admitted to the hospital after a health examination.

Brief summary: Fever is a common clinical symptom in patients with postoperative scoliosis. However, there are rare reports of immediately fevers occurring following operative procedures.

Detailed description: Postoperative fever is a common clinical symptom in patients following spinal surgery, with an incidence of 13.2%, and 64.5% of patients with neuromuscular scoliosis were observed to develop postoperative fevers. The most frequently observed cause of fever is surgical trauma, which is associated with inflammatory responses to surgery, and such fevers typically resolve within 2-3 days. This self-limited cause of postoperative fever is non-pathological,4 and the severity and duration of such fevers depend on the duration, scope, and type of surgery, and whether a mesh graft was inserted. The aetiology of immediate postoperative fever for patients following hip prosthesis implantation is unknown, and it is inexpedient to initiate antibiotic treatment or to increase the prophylactic antibiotic dosage. However, there are rare reports of chills and fevers occurring immediately following spinal surgery, to the best of our knowledge, there have been no reports on the mechanism of immediate postoperative fever following spinal surgery.

Based on this evidence and on observation, when patients experience postoperative fevers, nearly all surgeons seek to exclude infection as a cause. The case presented in this paper is that of a 15-year-old female with idiopathic scoliosis who underwent posterior idiopathic scoliosis incision and correction for pedicle fixation. The clinical symptoms of interest, including chills, a high fever, an increased heart rate and increased blood pressure, were observed immediately during the course of anaesthesia resuscitation. In this report, risk factors, treatment and prevention are assessed based on the case evidence.

Eligibility criteria: Inclusion Criteria:

* N/A

Exclusion Criteria:

* N/A

Primary outcomes:
measure: surgical complication
timeFrame: up to 3 years, after surgical procedure
Secondary outcomes:
Other outcomes:
Locations:
city: Zhanjiang
country: China
facility: The Affiliated Hospital of Guangdong Medical University
state: Guangdong
Study officials:
affiliation: Affiliated Hospital of Guangdong Medical University
name: Yiyue Zhong, Ph.D.
role: PRINCIPAL_INVESTIGATOR
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