Clinical trial NCT03395106: Public Health Messages to Address Vaccine Hesitancy
Official title: Developing and Evaluating Public Health Messages to Address Vaccine Hesitancy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Vaccine Hesitancy
Keywords: vaccine
public health
Lead sponsor: University of Manitoba
Sponsor class: OTHER
Collaborators: name: Canadian Immunization Research Network
First posted: 2018-01-10
Enrollment: 883
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Factorial design 2x2
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Views on vaccines range from those who are strongly supportive to those who are stridently opposed and will not budge from identity-based core beliefs about vaccines. In between these poles are numerous others who can delay, be reluctant (but still accept), or refuse/accept some vaccines for their children but not others. It is for these vaccine-hesitant parents that constitute the 'middle ground' of this spectrum where the most immediate and productive gains can be made towards enhancing vaccination acceptance and improving uptake. However, navigating this noisy communications environment is difficult, given the array of confusing and conflicting information available from multiple and competing sources. To date, there is no consensus on how best to use communication to respond to vaccine hesitancy. Building on two Canada-wide surveys of parents, the goal of this research is to identify which communication strategies show the greatest impact in reducing parental vaccine hesitancy and improving vaccination intentions.

The specific objectives are to:

1. Develop and pre-test four variations of news media stories that vary by source (parent versus physician) and content (intuitive versus deliberative);
2. Examine the impact of vaccine hesitant parents' exposure to vaccine communications that vary in source (parent versus physician) and content (intuitive versus deliberative) on primary (vaccine hesitant attitudes) and secondary (vaccine intentions) outcomes; and
3. Explore which media story variation may be more effective in improving vaccination attitudes and intentions for different parental decision-making styles (deliberative versus intuitive).


Eligibility criteria: Inclusion Criteria:

* Parents over 18 living in Canada with a YOUNGEST child is less than 24 months.

Exclusion Criteria:

* Parents who have a YOUNGEST child older than 24 months
* A parent who is pregnant, before the first trimester is complete

Primary outcomes:
measure: Vaccine Hesitancy
timeFrame: Change in baseline measured up to 1 day after content delivery
Secondary outcomes:
measure: Intention to Vaccinate
timeFrame: Change in baseline measured up to 1 day after content delivery
Other outcomes:
Locations:
city: Winnipeg
country: Canada
facility: University of Manitoba
state: Manitoba
Study officials:
affiliation: University of Manitoba
name: Michelle Driedger, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Pachur T, Spaar, M. Domain-specific preferences for intuition and deliberation in decision making. Journal of Applied Research in Memory and Cognition. 4:303-311, 2015.
citation: Opel DJ, Taylor JA, Zhou C, Catz S, Myaing M, Mangione-Smith R. The relationship between parent attitudes about childhood vaccines survey scores and future child immunization status: a validation study. JAMA Pediatr. 2013 Nov;167(11):1065-71. doi: 10.1001/jamapediatrics.2013.2483.