Clinical trial NCT06632847: Comparison of Device Based Inspiratory Muscle Training and Thera-band Resistive Training in Healthy Adults
Official title: Comparison of Inspiratory Muscle Training and Thera-band Resistive Training on Diaphragmatic Strength and Pulmonary Function of Healthy Adults.
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Healthy Young Adults
Keywords: Inspiratory muscle training
Thera-band resistive training
Healthy young adults
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-10-09
Enrollment: 56
Sex: ALL
Minimum age (years): 20
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: This study aims to evaluate the impact of inspiratory muscle training and Thera-band resistive training on pulmonary function and diaphragmatic strength of healthy adults. This trail investigate whether IMT can improve pulmonary function and diaphragmatic strength of healthy adults as well as overall respiratory health.

Detailed description: Inspiratory Muscle Training(IMT) has been shown to improve respiratory muscle strength and endurance in various conditions. This study aims to explore the effects of IMT specifically in healthy young adults. To assess whether a structured IMT program improves diaphragmatic strength and pulmonary function in healthy adults. A randomized control trail involving 56 competitive young healthy adults will be conducted. The study duration will be 8 weeks, with assessments conducted at baseline , mid-point, and at the end of intervention. The IMT group participate in 20 minutes of training session, 4 to 5 times per week, using power-breathe device. Thera-band resistive training group participate in 15 minutes of training session, 3 times per week, using different colors of thera-band. This study aims to provide robust evidence on the benefits of IMT for young healthy adults.

Eligibility criteria: Inclusion Criteria:

* Both male and female participants.
* 20 to 35 years
* FEV1/FVC ratio above 60%
* Non-smokers

Exclusion Criteria:

* Acute illness within last 2 weeks
* Obese patients whose BMI greater than 30kg
* Patient with history of chronic airflow limitation or any diagnosed disease.
* Patient with acute infection.

Primary outcomes:
measure: Peak Expiratory Flow Rate (PEFR)
timeFrame: 6 weeks
measure: Forced Vital Capacity (FVC)
timeFrame: 6 week
measure: Forced Expiratory volume in 1sec (FEV1)
timeFrame: 6 week
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Railway General Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Suman Sheraz, Phd
role: PRINCIPAL_INVESTIGATOR
References:
citation: Fernandez-Lazaro D, Corchete LA, Garcia JF, Jerves Donoso D, Lantaron-Caeiro E, Cobreros Mielgo R, Mielgo-Ayuso J, Gallego-Gallego D, Seco-Calvo J. Effects on Respiratory Pressures, Spirometry Biomarkers, and Sports Performance after Inspiratory Muscle Training in a Physically Active Population by Powerbreath(R): A Systematic Review and Meta-Analysis. Biology (Basel). 2022 Dec 29;12(1):56. doi: 10.3390/biology12010056.
citation: Qin L, Liu S, Hu S, Feng L, Wang H, Gong X, Xuan W, Lu T. The Effect of Inspiratory Muscle Training on Health-Related Fitness in College Students. Int J Environ Res Public Health. 2024 Aug 17;21(8):1088. doi: 10.3390/ijerph21081088.
citation: Van Hollebeke M, Gosselink R, Langer D. Training Specificity of Inspiratory Muscle Training Methods: A Randomized Trial. Front Physiol. 2020 Dec 3;11:576595. doi: 10.3389/fphys.2020.576595. eCollection 2020.