Clinical trial NCT06988917: Rehabilitation Efficacy of Low-Load Blood Flow Restriction Training for Lateral Patellar Compression Syndrome
Official title: Rehabilitation Efficacy of Low-Load Blood Flow Restriction Training for Lateral Patellar Compression Syndrome
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Lateral Patellar Compression Syndrome
Keywords: Lateral Patellar Compression Syndrome
patellofemoral joint
LL-BFRT
Lead sponsor: Peking University Third Hospital
Sponsor class: OTHER
First posted: 2025-05-25
Enrollment: 60
Sex: ALL
Minimum age (years): 30
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient with lateral patellar compression syndrome after lateral retinacular release

Brief summary: The purpose of this study is to understand the effect of low-load blood flow restriction training on the rehabilitation effect of patients after lateral patellar compression syndrome surgery, and to observe the differences between low-load blood flow restriction training combined with conventional rehabilitation training and conventional rehabilitation training. The main question it aims to answer is:

Can low-load blood flow restriction training improve the rehabilitation effect of patients after surgery for lateral patellar hypertension syndrome? Researchers compared conventional rehabilitation training with conventional rehabilitation training combined with low-load blood-limiting training to explore the effect of blood-limiting training combined with conventional rehabilitation training on the lower extremity function of patients after lateral patellar compression syndrome surgery, providing experimental and theoretical basis for formulating rehabilitation training programs.


Eligibility criteria: Inclusion Criteria:

1. Aged 30-60 years with a Visual Analog Scale (VAS) score ≥3;
2. Diagnosed with lateral patellar compression syndrome confirmed by MRI and clinical evaluation, having undergone arthroscopic lateral retinacular release surgery;
3. Presenting postoperative reduction in thigh circumference on the affected side, accompanied by quadriceps muscle atrophy and decreased muscle strength;
4. Minimum postoperative duration of ≥2 weeks, with signed informed consent and demonstrated ability to comply with the study protocol.

Exclusion Criteria:

1. Patients with concomitant fractures or other ligament injuries (including those with prior ACL reconstruction);
2. Individuals presenting with severe osteoarthritis or rheumatoid arthritis;
3. Those with medical histories of deep vein thrombosis, coagulation disorders, vascular diseases, or diabetes mellitus;
4. Subjects with active infections, malignancies, current pregnancy, or psychiatric disorders.

Primary outcomes:
measure: Lysholm score
timeFrame: 0-4week
measure: VAS score
timeFrame: 0-4week
measure: Peak torque of knee extension
timeFrame: 0-4week
measure: Quadriceps thickness
timeFrame: 0-4week
Secondary outcomes:
measure: Thigh circumference
timeFrame: 0-4week
measure: Range of motion of the knee joint
timeFrame: 0-4week
Other outcomes:
Locations:
city: Chongli
country: China
facility: Peking University Third Hospital of Chongli
state: Hebei
Study officials:
name: Yuping Yang
role: PRINCIPAL_INVESTIGATOR
References: