Clinical trial NCT03982251: The Effects of Whole Body Vibration in People With Chronic Stroke
Official title: The Effects of Whole Body Vibration Training With Different Frequencies on Bone Health and Neuromotor Performance in Individuals With Chronic Stroke: A Randomized Controlled Trial.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: vibration
bone
mucle
cerebrovascular accident
rehabilitation
Lead sponsor: The Hong Kong Polytechnic University
Sponsor class: OTHER
First posted: 2019-06-11
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function.

Detailed description: Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function in people with chronic stroke.

Eligibility criteria: Inclusion Criteria:

1. a diagnosis of stroke
2. stroke onset \>6 months
3. \>18 years of age
4. able to walk for short distance independently with or without walking aid
5. able to understand simple verbal commands

Exclusion Criteria:

1. neurological conditions other than stroke
2. significant musculoskeletal conditions (e.g. amputations)
3. metal implants in the lower extremity
4. previous fracture of the lower extremity
5. are currently taking bone resorption inhibitors or were taking the same before stroke.
6. significant peripheral vascular disease
7. vestibular disorders
8. pregnancy
9. Other serious illnesses that preclude the person from participating in the study

Primary outcomes:
measure: bone resorption marker
timeFrame: pre-test (week 0)
measure: bone resorption marker
timeFrame: post-test (week8)
Secondary outcomes:
measure: Six Minute Walk Test
timeFrame: pre-test (week 0)
measure: Six Minute Walk Test
timeFrame: post-test (week8)
measure: Gait velocity
timeFrame: pre-test (week 0)
measure: Gait velocity
timeFrame: post-test (week8)
measure: Spasticity
timeFrame: pre-test (week 0)
measure: Spasticity
timeFrame: post-test (week8)
Other outcomes:
Locations:
city: Hongkong
country: Hong Kong
facility: The Hong Kong Polytechnic University
Study officials:
affiliation: The Hong Kong Polytechnic University
name: Marco YC Pang, PhD
role: PRINCIPAL_INVESTIGATOR
References: