Clinical trial NCT07011277: Gait Characteristics of Women With Breast Cancer-Related Lymphedema
Official title: Investigation of Gait Characteristics in Women With Breast Cancer Related Lymphedema
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Breast Cancer Related Lymphedema
Keywords: breast cancer
lymphedema
gait disorders
upper extremity disorders
Lead sponsor: Gazi University
Sponsor class: OTHER
First posted: 2025-06-08
Enrollment: 40
Sex: FEMALE
Minimum age (years): 25
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study was conducted at the Oncological Rehabilitation Unit in Gazi University. Women with breast cancer related lymphedema (study group) who were referred to receive physiotherapy recommendations were included in the study.

Brief summary: Upper extremity lymphedema is one of the most common problems associated with cancer treatments in breast cancer survivors. Lymphedema causes asymmetry, changes posture, decreases arm swing due to increased weight, and as a result, may affects the patients' gait. The aim of this study is to examine the gait parameters in women with breast cancer-related lymphedema. Women diagnosed with breast cancer who are referred to the Gazi University Health Sciences Faculty Physiotherapy and Rehabilitation Department Oncological Rehabilitation Unit to receive physiotherapy recommendations and healthy volunteers will be included in the study. The demographic and clinical characteristics of the individuals will be recorded. Body Mass Index (BMI) will be calculated. Then, presence of lymphedema and lymphedema severity will be evaluated by measuring the circumference of the arms with a tape measure. Active shoulder joint movements will be evaluated with goniometer, handgrip strength with K-Force hand dynamometer, spatiotemporal parameters of gait and pelvic symmetry will be evaluated using BTS G-Walk wearable motion analysis system. Women with breast cancer related lymphedema will be compared with healthy women in terms of relevant parameters of gait. In addition, the relationship between lymphedema severity, shoulder joint movement limitation and grip strength with gait parameters in women with breast cancer and lymphedema will be analyzed.


Eligibility criteria: Inclusion Criteria:

* Having breast cancer related lymphedema
* Being between the ages of 25-70
* Completing cancer treatments

Exclusion Criteria:

* Having orthopedic, neurological or vision problems that may affect walking
* Being in the active treatment process (being in the acute phase after surgery, receiving chemotherapy or radiotherapy)

Primary outcomes:
measure: Lymphedema Severity
timeFrame: baseline
measure: Shoulder Range of Motion
timeFrame: baseline
measure: Handgrip Strength
timeFrame: baseline
measure: Spatio-temporal Gait Characteristics
timeFrame: baseline
measure: Pelvic Symmetry in Gait
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Gazi University Faculty of Health Sciences
Study officials:
References: