Clinical trial NCT05460442: Pericapsular Nerve Group Block Versus Fascia Iliaca Block for Pediatric Hip Surgery
Official title: Comparison of Ultrasound-Guided Pericapsular Nerve Group Block Versus Ultrasound-Guided Fascia Iliaca Block for Pediatric Hip Surgery
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Hip Surgery
Pericapsular Nerve
Fascia Iliaca
Lead sponsor: Tanta University
Sponsor class: OTHER
First posted: 2022-07-15
Enrollment: 75
Sex: ALL
Minimum age (years): 1
Maximum age (years): 6
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This compares the postoperative analgesic effect of ultrasound-guided pericapsular nerve group block (PENG) with ultrasound-guided fascia iliaca compartment block in pediatric patients undergoing hip surgery.

Detailed description: Surgeries involving hip joints in pediatric patients are associated with severe intraoperative and postoperative pain despite the use of systemic opioids.

Caudal block is the most commonly used method of regional anesthesia in children to control intraoperative and postoperative pain in surgeries involving lower limbs. However, there have been many side effects of caudal block such as hypotension, urine retention, excessive motor block, technical failure, nausea, and vomiting which may limit its use.

There are several techniques of ultrasound-guided regional anesthesia that are used to control acute pain in hip surgery with fewer side effects such as a lumbar plexus block, femoral nerve block, or a fascia iliaca compartment block.

The fascia iliaca compartment block (FICB) was described in 1989. It remains a popular regional anesthetic technique for surgical procedures involving the hip joint and femur. Local anesthetic (LA) is injected proximally beneath the fascia iliaca to block the femoral nerve (FN), obturator nerve (ON), and lateral cutaneous nerve of the thigh (LCNT) simultaneously.

The pericapsular nerve group (PENG) block was introduced to block the articular branches of the femoral, obturator, and accessory obturator nerves which provide sensory innervation to the hip. This regional anesthetic technique was described in 2018 for acute analgesia related to hip fractures.

Eligibility criteria: Inclusion Criteria:

* Pediatric patients
* aged 1-6 years old
* both sexes,
* American Society of Anesthesiologists (ASA) physical activity class I-II
* scheduled for elective hip surgery under general anesthesia.

Exclusion Criteria:

* Children with the severe systemic disease with American Society of Anesthesiologists physical activity class III or IV.
* Children with previous neurological or spinal disorders.
* Coagulation disorder.
* Infection at the block injection site.
* History of allergy to local anesthetics.

Primary outcomes:
measure: Total Opioids consumption
timeFrame: 24 hours postoperatively
Secondary outcomes:
measure: Postoperative pain
timeFrame: At post anesthesia care unit then after 30 minutes 2, 4, 6, 12, 24 hours.
measure: Time to first rescue analgesia
timeFrame: 24 hours Postoperatively
measure: Adverse effects
timeFrame: 24 hours Postoperatively
measure: Heart rate
timeFrame: Intraoperative then at post anesthesia care unit then after 30 minutes 2, 4, 6, 12, 24 hours
measure: Mean arterial blood pressure
timeFrame: Intraoperative then at post anesthesia care unit then after 30 minutes 2, 4, 6, 12, 24 hours.
Other outcomes:
Locations:
city: Tanta
country: Egypt
facility: Tanta University hospitals
Study officials:
References: