Clinical trial NCT04797845: Patient's TeleMonitoring With Amyotrophic Lateral Sclerosis Treated by Non Invasive Ventilation at Home.
Official title: "Patient's TeleMonitoring With Amyotrophic Lateral Sclerosis Treated by Non Invasive Ventilation at Home." Tele Monitoring Ventilation At Home (TM-VAH)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Amyotrophic Lateral Sclerosis
Noninvasive Ventilation
Keywords: Telemonitoring
amyotrophic lateral sclerosis
noninvasive ventilation
feasibility
Lead sponsor: University Hospital, Toulouse
Sponsor class: OTHER
First posted: 2021-03-15
Enrollment: 33
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: Single-center, prospective pilot study on patients with amyotrophic lateral sclerosis fitted with noninvasive ventilation. The objective is to assess the satisfaction of remote monitoring of patients on non-invasive ventilation after 12 months.

Detailed description: The non invasive ventilation is one of treatments used during the amyotrophic lateral sclerosis when patients have a chronic respiratory failure with alveolar hypoventilation signs. It is demonstrated to improve quality of life and prognosis of the disease. These patients, often severely disabled, generally have a negative experience of repeated hospitalizations. Despite everything, medical and paramedical monitoring is necessary, especially when they are fitted with non invasive ventilation (NIV). A quarterly reassessment is recommended . The possibilities of telemonitoring at home have grown considerably in recent years. In addition, the fans are currently able to remotely transfer a certain amount of data to the service provider, making remote monitoring feasible.Our project therefore aims to assess the feasibility of remote monitoring of patients with Amyotrophic Lateral Sclerosis (ALS) fitted with non invasive ventilation (NIV) through the assessment of their satisfaction, using both medical data and data provided by the ventilator. It is a single-center, prospective pilot study on 30 patients with amyotrophic lateral sclerosis fitted with noninvasive ventilation. Patients will benefit from a quarterly teleconsultation to assess the study criteria through questionnaires during 12 months. Ventilation machines make it possible to carry out remote monitoring, with the help of healthcare providers.

Eligibility criteria: o inclusion criteria:

* Patient over 18 years,
* Patient with Amyotrophic Lateral Sclerosis (ALS),
* Already fitted by Non Invasive Ventilation (NIV),
* Patient having signed the informed consent
* Patient affiliated to a social security scheme,
* Patient with a correct understanding of the French language,
* Patient with access to an internet connection at home.

For the caregiver:

* Adult person
* Be the patient's primary caregiver
* Have signed the informed consent intended for the caregiver

  o exclusion criteria:
* Patient with another cause of chronic respiratory failure: other neuromuscular diseases, Chronic obstructive pulmonary disease (COPD), diffuse interstitial lung disease,
* Patient under guardianship or under judicial protection,
* Patient dependent at least 20 hours out of 24 of the non invasive Ventilation (NIV).

Primary outcomes:
measure: Patient satisfaction of the telemonitoring of non invasive ventilation at home assessed by CSQ-8 at the end of the study
timeFrame: 1 year
Secondary outcomes:
measure: Effect of remote monitoring
timeFrame: every 3 months during 1 year
measure: Patient satisfaction during the study
timeFrame: every 3 months during 1 year
measure: Feasibility for caregivers assessed by Zarit questionnaire
timeFrame: every 3 months during 1 year
measure: Feasibility for caregivers assessed by Depression Anxiety Stress Scales (DASS-21) questionnaire
timeFrame: every 3 months during 1 year
measure: Feasibility for nursing staff
timeFrame: every 3 months during 1 year
Other outcomes:
Locations:
city: Toulouse
country: France
facility: Toulouse University Hospital
Study officials:
affiliation: University Hopsital Toulouse
name: Sandrine Pontier-Marchandise, MD
role: PRINCIPAL_INVESTIGATOR
References: