Clinical trial NCT06464406: Virtual Reality During Exercise Testing
Official title: Effects of Virtual Reality on Cardiorespiratory Fitness Test Results
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Virtual Reality
Keywords: virtual reality
cardiorespiratory fitness
anaerobic threshold
bicycle ergometer test
Lead sponsor: Augusta University
Sponsor class: OTHER
First posted: 2024-06-18
Enrollment: 24
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: This study will use a repeated-measures crossover model in which each participant completes the two conditions of the maximal exercise test (Control and Virtual Reality) in a randomized, counterbalanced order.
Primary purpose: OTHER

Brief summary: The goal of this clinical trial is to explore the effects of virtual reality use on maximal aerobic exercise test performance (aerobic capacity) in healthy adults. The main questions it aims to answer are:

* Does using a virtual reality program during a maximal aerobic exercise test lead to differences in VO2peak (maximal aerobic capacity)? and,
* Does using a virtual reality program during a maximal aerobic exercise test lead to differences in work rate at the ventilatory threshold?

Participants will complete a maximal aerobic exercise test two times (separated by 1 week of recovery) under the following conditions:

* normal testing conditions in a lab
* while viewing a virtual reality video

Researchers will compare the test results of both conditions to see if the use of a virtual reality program alters VO2peak or the ventilatory threshold.

Detailed description: Virtual reality imparts a dissociative effect on users during exercise, such that the physical activity task is experienced as more enjoyable and pleasant, requires less exertion, and requires less physiological function for a given submaximal work rate.

This array of positive effects may be particularly advantageous during a maximal aerobic exercise test, mainly because participant motivation and negative psychological state often lead to premature test termination. Ameliorating the unpleasantness of this type of exercise test with the use of virtual reality technology may prolong effort expenditure during the test and result in superior performance compared to a control condition.

Additionally, improving physiological function at submaximal work rates may lead to alterations in other important testing outcomes, particularly the ventilatory threshold. The ventilatory threshold is used as a reference point for prescribing exercise intensity. An intervention that modifies this value would have repercussions for physical fitness practitioners who prescribe exercise intensity relative to the ventilatory threshold.

The general purpose of this study is to determine the effect of virtual reality on maximal aerobic exercise test performance in healthy adults. The specific questions it aims to answer are:

* Does using a virtual reality program during a maximal aerobic exercise test lead to differences in VO2peak (maximal aerobic capacity)? and,
* Does using a virtual reality program during a maximal aerobic exercise test lead to differences in work rate at the ventilatory threshold?

Secondary questions this study aims to answer include:

Does using a virtual reality program during a maximal aerobic exercise test lead to differences in

* exercise test time?
* maximal heart rate during the exercise test?
* maximal respiratory exchange ratio (RER) during the exercise test?
* heart rate (HR) at the ventilatory threshold?
* RER at the ventilatory threshold?
* psychological response \[rating of perceived exertion (RPE) and affective valence\] throughout the exercise test?

To address these aims, participants will complete the same maximal aerobic exercise test on a cycler ergometer under normal laboratory conditions (Control) and when viewing an immersive virtual reality video (VR). The two tests will be completed in a randomized and counterbalanced order to account for learning or familiarity effects, and will be separated by 1 week to account for the effects of testing fatigue.

Respiratory data, HR, RPE, and affective valence were collected during the exercise tests to address the aims of the study.

Eligibility criteria: Inclusion Criteria:

-

Exclusion Criteria:

* Answering "YES" to one or more items on the Physical Activity Readiness Questionnaire (PAR-Q).
* Women who are pregnant at the time of participation according to a pregnancy test.

Primary outcomes:
measure: VO2peak
timeFrame: Assessed during the exercise test for each condition.
measure: Ventilatory threshold
timeFrame: Assessed during the exercise test for each condition.
Secondary outcomes:
measure: Peak power
timeFrame: Assessed during the exercise test for each condition.
measure: Total test time
timeFrame: Assessed during the exercise test for each condition.
measure: RPE
timeFrame: Assessed throughout the exercise test for each condition (at the end of the warm-up and end of every even-numbered stage)..
measure: Affective Valence
timeFrame: Assessed throughout the exercise test for each condition (at the end of the warm-up and end of every even-numbered stage)..
measure: %VO2peak at ventilatory threshold
timeFrame: Assessed during the exercise test for each condition.
measure: Heart rate at ventilatory threshold
timeFrame: Assessed during the exercise test for each condition.
measure: Heart rate at VO2peak
timeFrame: Assessed during the exercise test for each condition.
measure: Respiratory Exchange Ratio (RER) at VO2peak
timeFrame: Assessed during the exercise test for each condition.
measure: Respiratory Exchange Ratio (RER) at ventilatory threshold
timeFrame: Assessed during the exercise test for each condition.
Other outcomes:
Locations:
city: Augusta
country: United States
facility: Augusta University
state: Georgia
Study officials:
affiliation: Augusta University
name: Andrew R Moore, PhD
role: PRINCIPAL_INVESTIGATOR
References: