Clinical trial NCT06600347: Effect of DASH Diet and Progressive Muscle Relaxation on Cardiovascular Risks in Postmenopausal Women
Official title: Effect of DASH Diet and Progressive Muscle Relaxation on Cardiovascular Risks in Postmenopausal Women
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Cardiovascular Complication
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 90
Sex: FEMALE
Minimum age (years): 50
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will be conducted to investigate the effect of DASH diet and Progressive muscle relaxation on cardiovascular risks in postmenopausal women.

Detailed description: Cardiovascular disease is the leading cause of morbidity and mortality in men and women, but the incidence of cardiovascular disease related deaths is higher in women than men. Hypertension is one of the leading risk factors for cardiovascular disease. Aging in both men and women is characterized by increases in blood pressure (BP), but the age-related increases are more rapid in women particularly postmenopausal women than in men.

A variety of non-pharmacologic treatments to manage stress have been found effective in reducing blood pressure and the development of hypertension. The DASH eating pattern promotes blood pressure reduction by encouraging the consumption of foods that are low in saturated fat, total fat, cholesterol, and sodium and high in potassium, calcium, magnesium, fiber, and protein. In terms of actual food choices, the DASH eating pattern encourages whole grains, fat free or low-fat dairy products, fruits, vegetables, poultry, fish, and nuts. Foods that are limited include fatty meats, full-fat dairy products, tropical oils (e.g., coconut, palm, and palm kernel oils), and sweets and sugar sweetened beverages.

The mechanism by which relaxation techniques lower blood pressure is unclear. One theory suggests that they may help lower the stress and physiologic arousal produced by the autonomic nervous system, thereby reducing blood pressure. So this study is a trial to determine the effect of DASH diet and progressive muscle relaxation in reducing cardiovascular risks in postmenopausal women.

Eligibility criteria: Inclusion Criteria:

* The participant's ages will be ranged from 50- 60 years old.
* Their body mass index will be ranged from 30-35 kg/m2.
* All women are hypertensive at least one year postmenopause.
* Their scores in perceived stress scale will be ranged from 14-40.

Exclusion Criteria:

* Women with systolic blood pressure (SBP) \>160 mmHg or diastolic blood pressure (DBP) \>100mmHg.
* Women who have other known causes of hypertension, such as renal diseases.
* Women who are using sedatives or tranquilizer or antidepressant drugs.

Primary outcomes:
measure: Systolic blood pressure
timeFrame: 3 months
measure: Diastolic blood pressure
timeFrame: 3 months
measure: Low density lipoprotein
timeFrame: 3 months
measure: High density lipoprotein
timeFrame: 3 months
measure: Triglyceride level
timeFrame: 3 months
measure: Total cholesterol level
timeFrame: 3 months
Secondary outcomes:
measure: Stress measurement
timeFrame: 3 months
Other outcomes:
Locations:
city: Suez
country: Egypt
facility: Farahnaz Ahmed Mohamed
Study officials:
affiliation: Cairo University
name: Mohamed Awad, professor
role: STUDY_DIRECTOR
affiliation: National Institute of Nutrition
name: Heba Abdel Halim, PHD
role: STUDY_DIRECTOR
affiliation: Cairo University
name: Hala Emara, professor
role: STUDY_CHAIR
References: