Clinical trial NCT05882942: Matcha Green Tea Effects at Rest and During Moderate-intensity Exercise in Females
Official title: Effects of Matcha Green Tea on Heart Rate Variability, Substrate Oxidation and Cardiovascular Response at Rest and During Moderate-intensity Exercise in Females
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: No Condition
Lead sponsor: University of Chichester
Sponsor class: OTHER
First posted: 2023-05-31
Enrollment: 8
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Randomized, placebo-controlled, crossover design
Primary purpose: BASIC_SCIENCE

Brief summary: Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. This research will expand the insight on the effects by Matcha green tea supplementation and address the effects on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Detailed description: Intake of the catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition. EGCG is the most abundant and potent bioactive compound (50-80% of the total catechin content) found in Matcha green tea (MGT) and is usually consumed as a drink or in a capsulated from unfermented tea leaves. MGT polyphenols have antioxidant and anti-inflammatory properties, providing numerous health benefits, such as the reduced risk of type 2 diabetes and obesity. MGT supplementation (3g over a 24hr period) has been shown to enhance fat oxidation during 30-min brisk walking as well as lower respiratory exchange ratio in females. Understanding the effectiveness of the bioactive compounds found in natural food sources in improving human health is key to informing the general population and the public health policies preceding them; the daily consumption of drinks and food naturally high in EGCG content could be recommended as an essential part of a healthy lifestyle. This research will expand the insight on Matcha green tea supplementation address the effect on heart rate variability, substrate oxidation at rest, and cardiovascular responses at rest in addition to metabolic and physiologic responses for a 1-hr walk in healthy females.

Eligibility criteria: Inclusion Criteria:

* healthy
* non-smokers
* not taking any supplements
* no known allergy to green tea

Exclusion Criteria:

* smokers
* known high blood pressure
* on medication

Primary outcomes:
measure: Heart rate variability
timeFrame: Three weeks
measure: Carbohydrate oxidation
timeFrame: Three weeks
measure: Fat oxidation
timeFrame: Three weeks
measure: Cardiac output
timeFrame: Three weeks
measure: Stroke volume
timeFrame: Three weeks
measure: Total peripheral resistance
timeFrame: Three weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Chichester
country: United Kingdom
facility: Mark Willems
state: West Sussex
city: Chichester
country: United Kingdom
facility: University of Chichester
Study officials:
affiliation: University of Chichester
name: Mark E Willems
role: PRINCIPAL_INVESTIGATOR
References: