louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT03026270: Effect of Therapeutical Paraffin in the Malleability of Burned Skin
Official title: Effect of Therapeutical Paraffin Wax Bath in the Malleability of Burned Skin
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Burn
Keywords: Physiotherapy
Paraffin
Burn
Contracture
Lead sponsor: University of Sao Paulo
Sponsor class: OTHER
First posted: 2017-01-20
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: Effect of therapeutical paraffin wax bath in the malleability of burned skin

Detailed description: The altered biomechanical properties of the skin entail limitation of movement, it have been important the statement of resources aimed at increasing skin suppleness. The objective of the study is to evaluate the effect of therapeutic paraffin in biophysical characteristics of the burned skin with or without scar hypertrophic. For this, 60 volunteers will be evaluated in the age group of 18-60 years, of both sexes, with deep second degree and third degree burns and evaluated areas submitted to therapeutic procedures, divided evenly into scar areas and normal skin. Applications will be set randomly by lot, with cross design (cross-over), and a minimum interval of seven days (wash-out) of the activities. The biophysical and biomechanical parameters of the skin will be assessed noninvasively by Cutometer of the model (MPA) 580, device to measure elasticity of the upper skin layer using negative pressure, and the durometer, measure hardness of the skin, before, immediately after 0, 10, 20 and 30 minutes of intervention with therapeutic paraffin in different procedures (number of layers and thermal insulation). Sociodemographic, clinical and surgical data of the volunteers will be evaluated by SPSS 15 (Statistical Analysis Software). The normality of the data will be verified by the Shapiro-Wilk test, and the effect of therapeutic procedures over time evaluated by the Friedman test (intragroup) and the test Kruskal-Wallis post hoc Dunn for comparisons between different funds (intergroup), p \<0.05, will evaluated by software SPSS.

Eligibility criteria: Inclusion Criteria:

* Will be included in the study individuals who were victims of 2 deep burns or 3rd grade being subjected to grafting autogenous procedures, with or without the presence of hypertrophic scar, normal skin of individuals, ie without tissue damage and to agree to sign the term free and informed consent.

Exclusion Criteria:

* They will be included in this study individuals with diseases or deformities that affect the structure and function of the skin.

Primary outcomes:
measure: Distensibility of burned hypertrophic scar
timeFrame: up to 30 minutes
Secondary outcomes:
measure: Hardness of burned hypertrophic scar before, immediately after 0, 10, 20 and 30 minutes.
timeFrame: up to 30 minutes
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT06619470: Brain Wave Entrainment Using Alpha Frequency Binaural Beats on Adolescent Swimmers
Official title: Brain Wave Entrainment Using Alpha Frequency Binaural Beats on Adolescent Swimmers
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Athletes
Lead sponsor: Alexandria University
Sponsor class: OTHER
First posted: 2024-10-01
Enrollment: 11
Sex: ALL
Minimum age (years): 13
Maximum age (years): 15
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Relaxation techniques and binaural beats added to music have a positive effect on athletic performance of swimmers than music therapy and mental training alone

Detailed description: EEG measurement after Relaxation techniques and binaural beats added to music have been employed showed a positive effect on the athletic performance of swimmers when BB have been added to music therapy and mental training

Eligibility criteria: Inclusion Criteria:

- adolescent swimmer

Exclusion Criteria:

-

Primary outcomes:
measure: reaction time
timeFrame: 6 weeks
measure: EEG frequency
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT06453070: Hasan Kalyoncu University
Official title: Hasan Kalyoncu University
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Aggression
Forensic Psychiatric Patients
Keywords: Forensic Psychiatric Patients
Aggression
childhood traumas
cognitive distortions
nursing
Lead sponsor: Hasan Kalyoncu University
Sponsor class: OTHER
First posted: 2024-06-11
Enrollment: 103
Sex: MALE
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: They are people who do not have criminal liability, do not have a reading comprehension problem, and volunteer to participate in the research. Since the forensic women's service was not active, the sample consisted of 103 male patients.

Brief summary: Aggression is a serious problem that appears to be common in forensic psychiatric patients. Determining factors related to aggression is important for psychiatric nurses during the treatment, care and rehabilitation of patients. The aim of this study is to determine the relationship between childhood traumas, cognitive distortions and aggression in forensic psychiatry patients. This descriptive study was conducted with 103 male forensic psychiatry patients treated in a high security forensic psychiatry hospital. The data of study were collected Introductory Information Form, Childhood Psychological Traumas Scale (CTQ), Cognitive Distortions Scale (CDS) and Buss-Perry Aggression Scale (BAQ). In this study, 82.5% of forensic psychiatry patients were male, 50.5% were married, 49.5% had secondary education, 53.4% were not working. It was found that patients diagnosed with Schizophrenia Spectrum and Other Psychotic Disordersa and Bipolar Affective Disorders, who were hospitalised more than 5 times, who used alcohol/substances and who had previous experience of forensic events had higher levels of aggression. There was a significant positive correlation between the childhood traumas, cognitive distortions and aggression. The results of this study reveal important results that will contribute to psychiatric nurses caring for forensic psychiatric patients in determining the patients' aggression and affecting factors during the treatment and care process.


Eligibility criteria: Inclusion Criteria:

* people who do not have criminal liability
* do not have a reading comprehension problem
* volunteers to participate in the research

Exclusion Criteria:

* Patients who did not agree to participate in the study or who left the study

Primary outcomes:
measure: There was a significant correlation between the childhood traumas and aggression
timeFrame: Four mounth
measure: There was a significant correlation between the cognitive distortions and aggression
timeFrame: Four mounth
Secondary outcomes:
Other outcomes:
Locations:
city: Elazığ
country: Turkey
facility: Forensic Psychiatry Unit of Elazığ Fethi Sekin City Hospital
Study officials:
References:
Clinical trial NCT02774070: Characteristics of Rheumatoid Arthritis Patients With Atlantoaxial Synovitis Detected by Plain X-ray and MRI
Official title: Characteristics of Rheumatoid Arthritis Patients With Asymptomatic Versus Symptomatic Atlantoaxial Joint Affection Detected by Plain X-ray and Magnetic Resonance Imaging
Study type: INTERVENTIONAL
Overall status: WITHDRAWN
Phase: NA
Conditions: Neck Pain
Keywords: AAJ RA MRI synovitis
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2016-05-17
Enrollment: 0
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SCREENING

Brief summary: This study detects the presence of atlantoaxial joint affection in symptomatic versus asymptomatic rheumatoid arthritis patients revealed by plain X-ray and magnetic resonance imaging of the cervical spine

Detailed description: Atlantoaxial joint affection in rheumatoid arthritis patients may have life-threatening complications if not detected early. It may not be detected unless it becomes symptomatic. However, asymptomatic atlantoaxial joint affection is not uncommon. Investigators will try to detect atlantoaxial joint affection at an early stage and its relation to symptomatology and other disease criteria. So investigators will use conventional plain X-ray examination combined with magnetic resonance imaging of the cervical spine to detect soft tissue as well as bony changes of this condition.

Eligibility criteria: Inclusion Criteria:

* Rheumatoid arthritis patients complaining or not complaining of atlantoaxial affection symptomatology

Exclusion Criteria:

* Pregnant females
* Patients with pacemakers or metallic bony plates.
* Patients that have claustrophobia

Primary outcomes:
measure: Prevelance of atlantoaxial joint affection in clinically and laboratory proven rheumatoid arthritis patients
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Assiut University
name: Nisreen A Abbas, Doctor
role: PRINCIPAL_INVESTIGATOR
References:
citation: Yurube T, Sumi M, Nishida K, Miyamoto H, Kohyama K, Matsubara T, Miura Y, Hirata H, Sugiyama D, Doita M. Accelerated development of cervical spine instabilities in rheumatoid arthritis: a prospective minimum 5-year cohort study. PLoS One. 2014 Feb 18;9(2):e88970. doi: 10.1371/journal.pone.0088970. eCollection 2014.
citation: Nazarinia M, Jalli R, Kamali Sarvestani E, Farahangiz S, Ataollahi M. Asymptomatic atlantoaxial subluxation in rheumatoid arthritis. Acta Med Iran. 2014;52(6):462-6.
Clinical trial NCT03836170: Analysis of the Impact of Cholecystectomy on Gut Microbiome in Adults
Official title: Analysis by High-throughput Sequencing: the Impact of Cholecystectomy on Gut Microbiome in Adults
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE1
Conditions: Laparoscopic Cholecystectomy
Keywords: laparoscopic cholecystectomy
gut microbiota
Lead sponsor: Shanghai Jiao Tong University School of Medicine
Sponsor class: OTHER
First posted: 2019-02-11
Enrollment: 40
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: BASIC_SCIENCE

Brief summary: Laparoscopic cholecystectomy (LC) is widely used in the gallbladder stone, gallbladder polyp, gallbladder cancer and other diseases. Some of the patients would develop diarrhea after surgery, and studies have reported an increased risk of colorectal cancer after LC. The aim of the present study was to examine the effects of LC on the gut microbiota.


Eligibility criteria: Inclusion Criteria:

1. Gallbladder polyps diameter mm \>10;
2. The history of the symptoms of patients with gallbladder stones, there was no history of acute attack in the past month;
3. Age \<70 years old;
4. No serious systemic diseases such as diabetes, hypertension, heart disease, lung disease and so on/American anesthesia Association (ASA) grade I or II;
5. BMI\<30;
6. Families have better care and observation, and away from the hospital within 1 hours; patients and their families understand the process of ambulatory surgery (24 hours) and the pros and cons.

Exclusion Criteria:

1. Less than 18 years old;
2. With previous gastric surgery ;
3. Major systemic diseases ;
4. Pregnancy or lactation;
5. The use of antibiotics or yogurt within 2 months before the study.

Primary outcomes:
measure: Change of gut microbiota after laparoscopic cholecystectomy
timeFrame: Three months and one year after completion of LC
Secondary outcomes:
Other outcomes:
Locations:
city: Shanghai
country: China
facility: Renji Hospital, School of Medicine, Shanghai Jiao Tong University
state: Shanghai
Study officials:
affiliation: Renji Hospital, School of Medicine, Shanghai Jiao Tong University
name: Hong Lu, M.D.
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04110470: Comparison of the Safety and Cost of a Simplified Post-Operative Radiograph (SPOR) Protocol
Official title: Definitive Study for Non-inferiority Randomized Control Trial Comparing the Safety and Cost of a Simplified Post-Operative Radiographic (SPOR) Protocol for Selected Fractures
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Fractures, Bone
Fracture Complications
Xray Complication
Lead sponsor: University of Manitoba
Sponsor class: OTHER
First posted: 2019-10-01
Enrollment: 1612
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The standard post-operative radiographic protocol for the monitoring of fractures at Health Sciences Centre includes post-operative in hospital radiographs as well as radiographs at the two week follow up appointment. This is in addition to good quality intra-operative radiographs. With current operative techniques and implants, orthopaedic surgeons can achieve reliably stable internal fixation. In fact, patients are often allowed to take weight through the fractured limb immediately post-operatively. In these cases, redundant post-operative radiographs likely represent an avoidable cost to the system financially, and an avoidable cost to the patient in additional time spent in hospital and unnecessary radiation exposure.


Eligibility criteria: Inclusion Criteria:

* At least one lag screw for each fracture line
* At least one compression plate across each fracture line
* Locked intramedullary nail
* Articular/peri-articular fracture with antiglide/under-contoured plate
* Tension band technique (plate included) in simple fracture pattern
* Operating surgeon is confident in fixation construct, despite non-load sharing criteria.

Exclusion Criteria:

* Fracture \>21 days old
* Age \<18 years, or open growth plates
* Articular fracture with depression
* Multiple orthopaedic fractures
* History or radiographic appearance of osteoporosis/osteopenia or poor operative bone quality
* Likely difficulty with follow-up in first 6 weeks

Primary outcomes:
measure: Safety of a simplified post-operative radiographic protocol for fractures with stable fixation.
timeFrame: At six weeks.
measure: Cost-effectiveness of a simplified post-operative radiographic protocol for fractures with stable fixation.
timeFrame: At six weeks.
Secondary outcomes:
measure: Patient satisfaction: with a simplified post-operative radiographic protocol.
timeFrame: At six weeks.
Other outcomes:
Locations:
Study officials:
affiliation: University of Manitoba
name: Tudor V Tufescu, BSc, MD, FRCSC
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01067170: Pneumatic Compression Stockings During Hemodialysis
Official title: The Effect of Pneumatic Compression Stockings on Hemodynamic Parameters in Hemodialysis Patients: A Randomized Crossover Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hemodialysis
Keywords: Hemodialysis
Intradialytic hypotension
Lead sponsor: University of Calgary
Sponsor class: OTHER
First posted: 2010-02-11
Enrollment: 51
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: PREVENTION

Brief summary: This study aims to determine the effect of pneumatic compression devices (PCDs) on central blood volume in hemodialysis patients. We hypothesize that PCDs will help maintain central blood volume, and therefore prevent sudden decreases in blood pressure during hemodialysis.


Eligibility criteria: Inclusion Criteria:

* on hemodialysis at least 3 months
* on hemodialysis at least 3 times per week

Exclusion Criteria:

* dialyzing with a central venous catheter
* vascular access dysfunction
* peripheral vascular disease
* active medical issue
* unable to provide informed consent

Primary outcomes:
measure: Central blood volume
timeFrame: pre and post hemodialysis
Secondary outcomes:
measure: cardiac output
timeFrame: pre and post hemodialysis
measure: cardiac index
timeFrame: pre and post hemodialysis
measure: systemic vascular resistance
timeFrame: pre and post hemodialysis
measure: intracellular fluid volume
timeFrame: pre and post hemodialysis
measure: extracellular fluid volume
timeFrame: pre and post hemodialysis
measure: total body water
timeFrame: pre and post hemodialysis
Other outcomes:
Locations:
city: Calgary
country: Canada
facility: University of Calgary
state: Alberta
Study officials:
affiliation: University of Calgary
name: Jennifer M MacRae, MD MSc
role: PRINCIPAL_INVESTIGATOR
References:
citation: Tai DJ, Ahmed SB, Palacios-Derflingher L, Hemmelgarn BR, MacRae JM; Alberta Kidney Disease Network. Pneumatic compression devices during hemodialysis: a randomized crossover trial. Nephrol Dial Transplant. 2013 Apr;28(4):982-90. doi: 10.1093/ndt/gfs502. Epub 2012 Nov 7.
Clinical trial NCT01207570: Endermotherapy for Children With Developmental Disabilities
Official title: Effect of Endermotherapy on Passive Ankle Range of Motion in Children With Developmental Disabilities
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Cerebral Palsy
Developmental Delay
Keywords: flexibility
muscle
stretching
cerebral palsy
developmental
Lead sponsor: The Hong Kong Polytechnic University
Sponsor class: OTHER
Collaborators: name: Phoelia Co. Ltd.
First posted: 2010-09-23
Enrollment: 54
Sex: ALL
Minimum age (years): 2
Maximum age (years): 6
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: Children with developmental disabilities often sustain decreased range of motion in their extremities. The decrease in flexibility may be due to neuromuscular disorders such as spasticity or dystonia. Other causes may be imbalance in muscle strength surrounding a joint, leading to inappropriate habitual posture. Over time, muscle contracture may result for those muscle groups that are placed in a shortened position for an extended period of time. The most common site of muscle contractures among these children are gastrocnemius/soleus (lower limbs), and latissimus dorsi muscles (upper limbs). Muscle contractures can lead to further decline in functional abilities. Therefore, it is important to identify effective intervention strategies to enhance or maintain muscle flexibility in children with developmental dysfunctions.

Commercially available endermotherapy device has been used to soften scar tissue following burn injuries. The mechanical stimulation applied may also have beneficial effects on relaxing the muscle tissue. The overall aim of the proposed study is to determine whether endermotherapy treatment has immediate effect in improving joint range of motion among children with developmental disabilities.

The research hypothesis is that children in the endermotherapy group will have significantly more gain in ankle passive range of motion than those in the control group.


Eligibility criteria: Inclusion Criteria:

* children aged between 2 and 6.
* children with diagnosis of cerebral palsy or developmental disabilities.
* Has limited ankle dorsiflexion range of motion (less than 20 degrees)

Exclusion Criteria:

* Other serious illnesses that preclude participation

Primary outcomes:
measure: Ankle Passive Range of Motion
timeFrame: day 1 before treatment
measure: Ankle Passive Range of Motion
timeFrame: day 4 before treatment
measure: Ankle Passive Range of Motion
timeFrame: Day 1 after treatment
measure: Ankle Passive Range of Motion
timeFrame: Day 4 after treatment
Secondary outcomes:
Other outcomes:
Locations:
city: Hong Kong
country: Hong Kong
facility: Heep Hong Society
Study officials:
affiliation: The Hong Kong Polytechnic University
name: Marco Y P, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05306470: Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa
Official title: Ethyl Chloride-Endo Ice Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa - a Randomized Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pain
Symptomatic Irreversible Pulpitis
Lead sponsor: Altamash Institute of Dental Medicine
Sponsor class: OTHER
First posted: 2022-04-01
Enrollment: 90
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Local anesthesia in the oral cavity is a pain full experience for the patient. All means should be made to reduce the pain and anxiety of the patient for needle stick procedures. My study aims in elevating the pain experienced by the patient during this procedure by using either cold application with ethyl chloride or 5% lidocaine gel.

Detailed description: Local anesthetic procedure is always a dreadful experience for the patient specially for the patients who are already in pain . It is a job of the dentist to provide a painless dental treatment from the very beginning. Most dental procedures require administration of local anesthesia for a painless procedure with local anesthesia procedure being painful itself with the administration of needle in the oral cavity. Dentist everyday in their practice utilise various techniques and procedures in alleviating this painful experience with either application of lidocaine gel or spray . Numbing the oral mucosa with cold application is well documented and tested therefore my study aims in application of ethyl chloride spray on cotton pallet for a duration of 30 seconds in producing the desired numbing effect of the oral mucosa before infiltration of local anesthesia in alleviating the needle prick sensation perceived by the patient.

Pain level is assigned to one of four categorical scores using visual analogue scale

1. :None(0)
2. : Mild (1-3)
3. : Moderate (4-6)
4. : Severe (7-10)

Eligibility criteria: Inclusion Criteria:

* No medical history
* No age restrictions
* Patients suffering from Symptomatic Irreversible Pulpitis requiring buccal infiltration

Exclusion Criteria:

* Patients having any medical conditions considered to affect patient safety or the quality of the study
* if they had any known hypersensitivity to local anaesthetics of amide type or any of the other contents in the substance used

Primary outcomes:
measure: Post oral local anesthetic infiltration pain
timeFrame: immediately after completion of administration of oral local anesthetic infiltration within 60 seconds
Secondary outcomes:
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: Hira Danish
state: Sindh
Study officials:
References: