Clinical trial NCT06152133: Telerehabilitation, Core Stability Exercises and Hereditary Ataxia (TRCore-ataxia)
Official title: Effects of a Telerehabilitation Program of Central Stability Exercises to Improve Balance and Gait in Hereditary Ataxia. A Randomized Controlled Pilot Study.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hereditary Ataxia
Spinocerebellar Degenerations
Cerebellar Ataxia
Keywords: Spinocerebellar Degenerations
Telerehabilitation
Exercise
Lead sponsor: Universitat de Lleida
Sponsor class: OTHER
Collaborators: name: Universitat Internacional de Catalunya
name: Hospital Clinic of Barcelona
name: Universidad Europea de Madrid
First posted: 2023-11-30
Enrollment: 12
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized Controlled Pilot
Primary purpose: TREATMENT

Brief summary: Hereditary ataxias (HA) are a heterogeneous group of degenerative diseases of the cerebellum, brain stem and spinal cord. People who suffer from AH, among other symptoms, present deficiencies in the stability of the trunk, which leads to an alteration in postural control, with a strongly influential factor in the loss of balance and gait disorders. Improving the functionality of these physical aspects can help reduce the rate of falls, increase autonomy and quality of life for people with HA.

Evidence suggests that rehabilitation strategies based on core stability exercises (CSE) are effective in improving balance and postural control in several neurological diseases, such as stroke. However, there is little evidence with people with HA. In a previous study carried out by researchers of this project, in which an EEC exercise program was piloted at home, low adherence to treatment was perceived due to the little follow-up that was given to the participants. Therefore, including telerehabilitation in these programs would increase follow-up and could influence adherence.


Eligibility criteria: Inclusion Criteria:

* Suffer from degenerative HA at any stage of the disease (Spinocerebellar ataxia, Friedreich's ataxia, sporadic idiopathic cerebellar ataxia and neurodegenerative diseases where ataxia is the dominant symptom).
* Adults over 18 years of age.
* Be able to use a computer or mobile phone (It will be evaluated using the DILE scale)
* Have an internet connection.

Exclusion Criteria:

* Suffer from other neurological diseases and inability to follow simple instructions. -
* Suffering from a musculoskeletal injury that prevents you from performing the exercises.
* Being unable to maintain standing for more than 10 seconds without support (assessed with item 2 on the SARA scale).

Primary outcomes:
measure: Rate of dynamic sitting balance and trunk coordination
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
measure: Static sitting balance and Standing balance
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
measure: Walking Speed
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
Secondary outcomes:
measure: ADLs
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
measure: Lower extremity strength
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
measure: Adherence to treatment
timeFrame: T1: 7 weeks and T0: follow up 7 weeks
measure: Risk of falls
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
measure: Severity of ataxia
timeFrame: T0: Baseline, T1: 7 weeks and T0: follow up 7 weeks
measure: Treatment compliance
timeFrame: T1: 7 weeks and T0: follow up 7 weeks
measure: Program satisfaction
timeFrame: T1: 7 weeks
Other outcomes:
Locations:
city: Lleida
country: Spain
facility: University of Lleida
Study officials:
References: