Clinical trial NCT05900713: Effect of DNS Exercises Training on Hypertension
Official title: Effect of Dynamic Neuromuscular Stabilization Training on Postural Control in Patients With Essential Hypertension
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Essential Hypertension
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2023-06-12
Enrollment: 60
Sex: MALE
Minimum age (years): 50
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: parallel study is a type of clinical study in which two or more groups of participants receive different interventions.
Primary purpose: TREATMENT

Brief summary: Purpose of the study This study will be conducted to investigate any significant effect of dynamic neuromuscular stabilization training on postural control in patients with essential hypertension.

Detailed description: PURPOSE:

This study will be conducted to investigate any significant effect of dynamic neuromuscular stabilization training on postural control in patients with essential hypertension.

BACKGROUND:

The most recent global estimates suggested that hypertension (HTN) affected 1.13 billion people worldwide.

Raised blood pressure (BP) has emerged as the most important risk factor for global morbidity and mortality.

Hypertensive individuals present slower processing speed, reduced static and dynamic balance, decreased functional mobility during both single and dual tasking and higher fear of falling in comparison to normotensive individuals. These findings expand the body of knowledge about the effects of HTN on physical functions like prolonged processing time, disturbed balance and reduced mobility functions, which may guide clinicians in including preventive and rehabilitative strategies to their therapy protocols in order to improve the quality of life of the individuals with HTN.

HYPOTHESES:

Null Hypothesis: there will be no significant effect of dynamic neuromuscular stabilization training on postural control in patients with essential hypertension.

RESEARCH QUESTION: Will be any significant effect of dynamic neuromuscular stabilization training on postural control in patients with essential hypertension?

Eligibility criteria: Inclusion Criteria:

1. Sixty men patients with stage two essential HTN (more than 140/90 mm hg).
2. Their age will be ranged from 50-60 years old.
3. Body mass index (BMI) from 25 to 34.9 kg/m2.
4. Low levels of physical activity (using the International Physical Activity Questionnaire-Short Version) (The Arabic version of the questionnaire will be used)

Exclusion Criteria:

1. Uncontrolled HTN.
2. Diabetes mellitus.
3. Heavy Smoker.
4. Neurological or musculoskeletal conditions that interfere with gait
5. Vertebrobasilar insufficiency (VBI).
6. Use of psychotropic drugs.
7. Impaired vision and/or hearing.
8. Unstable medical conditions.
9. Patients who are unable to follow verbal instructions.
10. Participation in regular exercise training of any type in the previous 3 months.

Primary outcomes:
measure: Postural control by Biodex Balance System
timeFrame: 8 weeks
measure: balance by The Modified star excursion balance test (mSEBT)
timeFrame: 8 weeks
measure: dynamic balance and functional mobility by Timed-Up-and-Go test (TUG)
timeFrame: 8 weeks
Secondary outcomes:
measure: Sleep quality: using The Pittsburgh Sleep Quality Index (PSQI)
timeFrame: 8 weeks
measure: Quality of life: using The 12 Item Short Form Health Survey (SF-12) Questionnaire
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Faculty of Physical Therapy
Study officials:
affiliation: Cairo University
name: Shymaa Mohamed Ali, lecturer
role: STUDY_DIRECTOR
References:
citation: Ozaldemir I, Iyigun G, Malkoc M. Comparison of processing speed, balance, mobility and fear of falling between hypertensive and normotensive individuals. Braz J Phys Ther. 2020 Nov-Dec;24(6):503-511. doi: 10.1016/j.bjpt.2019.09.002. Epub 2019 Sep 23.
citation: Ghavipanje V, Rahimi NM, Akhlaghi F. Six Weeks Effects of Dynamic Neuromuscular Stabilization (DNS) Training in Obese Postpartum Women With Low Back Pain: A Randomized Controlled Trial. Biol Res Nurs. 2022 Jan;24(1):106-114. doi: 10.1177/10998004211044828. Epub 2021 Sep 23.