Clinical trial NCT06330649: The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism
Official title: The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cardiovascular Diseases
Hypertension
Diet
Keywords: Energy metabolism
Arterial blood pressure
heart rate
Lead sponsor: The University of Texas at Arlington
Sponsor class: OTHER
First posted: 2024-03-26
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Individuals will be randomly assigned to either an experimental or a control condition.
Primary purpose: PREVENTION

Brief summary: The objective of this protocol is to investigate the effect of consumption of a commercially available energy drink beverage on blood pressure, heart rate, and energy metabolism

Detailed description: Energy drink consumption has gained a lot in popularity and represents one of the most rapidly growing segments of the beverage industry. While regularly discussed in media outlets etc. the cardiovascular effects are not well described or well known. For example, the impacts on various cardiovascular parameters range from improved, decreased, to not impacted at all depending on the source. This can be due to a number of reasons including, study protocol design, study population tested, energy drink product used, volume consumed, etc. Accordingly, this study aims to investigate the impact of acute consumption of a standard commercially available can of energy drink beverage on the following parameters.

* Arterial blood pressure
* Heart rate
* Energy metabolism (oxygen consumption and carbon dioxide production

It is hypothesized that consumption of a 12 oz energy drink will result in modest elevations in arterial blood pressure, heart rate, and energy metabolism relative to when consuming of an equal volume of water.

Eligibility criteria: Inclusion Criteria:

* Between ages 18-30
* Must be free of reported cardiovascular, respiratory, and metabolic diseases.
* Must be caffeine naïve
* Must be fasted

Exclusion Criteria:

* Food allergies
* pregnant women
* Breast feeding women
* Individuals with cardiac, cardiovascular, respiratory, metabolic, and/or neurological disorders
* taking any prescription vasoactive medications
* allergies to spandex/lycra

Primary outcomes:
measure: Peripheral blood pressure in millimeters of mercury
timeFrame: baseline & 30, 60, 90, 120 min following beverage consumption
measure: Oxygen consumption milliliters per kilogram of body weight per minute
timeFrame: baseline & 30, 60, 90, 120 min following beverage consumption
measure: Heart rate in beats per minute
timeFrame: baseline & 30, 60, 90, 120 min following beverage consumption
Secondary outcomes:
Other outcomes:
Locations:
city: Arlington
country: United States
facility: UT Arlington - Science and Engineering Innovation and Research Building
state: Texas
Study officials:
affiliation: University of Texas at Arlington
name: Robert M Brothers, PhD
role: PRINCIPAL_INVESTIGATOR
References: