Clinical trial NCT01152606: A Study of Cardiac Safety in Patients With HER2 Positive Early Breast Cancer Treated With Herceptin
Official title: An Observational Study of Cardiac Events in Patients With HER2 Positive Early Breast Cancer Treated With Herceptin
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Breast Cancer
Lead sponsor: Hoffmann-La Roche
Sponsor class: INDUSTRY
First posted: 2010-06-29
Enrollment: 3942
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: HER2-positive Breast Cancer

Brief summary: This is a single cohort observational safety study. All patients will be treated and monitored according to the local clinical practice. No additional procedures/patient visits in comparison with the usual clinical practice are planned for the study. Data will be collected from centre's medical records for up to 5 years or death.


Eligibility criteria: Inclusion Criteria:

* All patients who are considered candidates to receive Herceptin for this indication

Exclusion Criteria:

* Patients for whom Herceptin is contraindicated

Primary outcomes:
measure: Incidence of symptomatic congestive heart failure\n(CHF) using New York Heart Association class II, III and IV, and cardiac death
timeFrame: On treatment and up to 5 years follow-up
Secondary outcomes:
measure: Time to onset and the time to recovery of symptomatic congestive heart failure
timeFrame: On treatment and up to 5 years follow-up
measure: Incidence of asymptomatic cardiac failure and other significant cardiac conditions
timeFrame: On treatment and up to 5 years follow-up
Other outcomes:
Locations:
city: Graz
country: Austria
facility: Lkh-Univ. Klinikum Graz; Klinik Für Gynäkologie
city: Graz
country: Austria
facility: LKH-UNIV. KLINIKUM GRAZ; Klinische Abteilung für Onkologie
city: Klagenfurt
country: Austria
facility: Lhk Klagenfurt; Abt. Für Gynäkologie
city: Leoben
country: Austria
facility: LKH Hochsteiermark; Abt. für Innere Medizin
city: Linz
country: Austria
facility: Ordensklinikum Linz Barmherzige Schwestern; Abt. fur Innere Medizin 1
city: Rankweil
country: Austria
facility: Lhk Feldkirch; Interne Medizin Abt.
city: Salzburg
country: Austria
facility: Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt.
city: St Veit An Der Glan
country: Austria
facility: A. Ö. Krankenhaus Der Barmherzigen Brüder; Abt. Für Chirurgie
city: Steyr
country: Austria
facility: A.Ö. Lhk; Ii. Medizinische Abt. Mit Schwerpunkt Gaströnter. & Onkologie
city: Vöcklabruck
country: Austria
facility: Lhk Vöcklabruck; Ii. Interne Abt.
city: Wels
country: Austria
facility: Klinikum Kreuzschwestern Wels; Iv. Interne Abt.
city: Wien
country: Austria
facility: Krankenanstalt Rudolfstiftung; I. Med. Abt.
city: Wien
country: Austria
facility: Medizinische Universität Wien; Univ.Klinik für Frauenheilkunde - Klinik für Gynäkologie
city: Wien
country: Austria
facility: Medizinische Universität Wien; Univ.Klinik für Innere Medizin I
city: Wien
country: Austria
facility: Wilhelminenspital; I. Medizinische Abt.
city: Antwerpen
country: Belgium
facility: ZNA Middelheim
city: Baudour
country: Belgium
facility: CH EpiCURA Site Louis Caty
city: Brasschaat
country: Belgium
facility: AZ KLINA
city: Brugge
country: Belgium
facility: AZ Sint Jan
city: Bruxelles
country: Belgium
facility: HIS (Etterbeek Ixelles)
city: Bruxelles
country: Belgium
facility: Hospital Erasme; Neurologie
city: Bruxelles
country: Belgium
facility: Cliniques Universitaires St-Luc
city: Edegem
country: Belgium
facility: UZ Antwerpen
city: Kortrijk
country: Belgium
facility: AZ Groeninge (Kennedylaan)
city: Liège
country: Belgium
facility: CHU Sart-Tilman
city: Namur
country: Belgium
facility: Clinique Ste-Elisabeth
city: Ottignies
country: Belgium
facility: Clinique St Pierre asbl
city: Roeselare
country: Belgium
facility: AZ Delta (Campus Wilgenstraat)
city: Sint Niklaas
country: Belgium
facility: AZ Nikolaas (Sint Niklaas)
city: Turnhout
country: Belgium
facility: AZ Turnhout Sint Elisabeth
city: Wilrijk
country: Belgium
facility: Sint Augustinus Wilrijk
city: Aschaffenburg
country: Germany
facility: Studienzentrum Aschaffenburg
city: Bad Soden
country: Germany
facility: Internist; Praxis Für Haemotologie & Onkologie
city: Bassum
country: Germany
facility: Brustzentrum Bassum
city: Berlin
country: Germany
facility: Onkologische Schwerpunktpraxis Kurfürstendamm
city: Berlin
country: Germany
facility: Praxis Dr. Schoenegg
city: Berlin
country: Germany
facility: DRK Kliniken Berlin Köpenick, Frauenklinik
city: Berlin
country: Germany
facility: Praxis Dr Geuther
city: Bielefeld
country: Germany
facility: Onkologische Schwerpunktpraxis Bielefeld; Haemotologie & Internistische onkologie
city: Bonn
country: Germany
facility: Medizinisches Versorgungszentrum Bonn
city: Bonn
country: Germany
facility: Universitätsklinikum Bonn; Zentrum für Geburtshilfe und Frauenheilkunde
city: Donauwörth
country: Germany
facility: Med. Versorgungszentrum Filiale Donauwörth Onkologisches Zentrum
city: Donauwörth
country: Germany
facility: Onkologisches Zentrum; Oncology
city: Dortmund
country: Germany
facility: St. Johannes Hospital
city: Dresden
country: Germany
facility: Praxis im Elbcenter 1 in Dresden-Pieschen; Dr. med. Thomas Goehler & Dipl.-Med. Steffen Doerfel
city: Dresden
country: Germany
facility: BAG Freiberg-Richter, Jacobasch, Illmer, Wolf
city: Dresden
country: Germany
facility: Universitätsklinikum "Carl Gustav Carus"; Frauenheilkunde und Geburtshilfe
city: Düsseldorf
country: Germany
facility: Universitätsklinikum Düsseldorf; Frauenklinik
city: Ebersberg
country: Germany
facility: Kreisklinik Ebersberg; Abteilung für Gynäkologie & Geburtshilfe
city: Erlangen
country: Germany
facility: Universitätsklinikum Erlangen; Frauenklinik
city: Eschweiler
country: Germany
facility: St Antonius Hospital; Frauenklinik
city: Essen
country: Germany
facility: Uniklinik Essen; Gynäkologie
city: Frankfurt am Main
country: Germany
facility: Hämatologisch-Onkologische Gemeinschaftspraxis am Bethanien-Krankenhaus
city: Freiburg
country: Germany
facility: Praxis für Interdisziplinäre Onkologie und Hämatologie GbR
city: Fulda
country: Germany
facility: Klinikum Fulda gAG; Frauenklinik
city: Georgsmarienhütte
country: Germany
facility: Klinikum St. Georg GmbH; Franziskus-Hospital Harderberg; Klinik für Gynaekologie und Geburtshilfe
city: Goch
country: Germany
facility: Wilhelm-Anton-Hospital Klinik f.Hämatologie und internistische Onkologie
city: Halle
country: Germany
facility: Martin-Luther-Universität Halle-Wittenberg
city: Hamburg
country: Germany
facility: Universitätsklinikum Hamburg-Eppendorf; Frauenklinik
city: Hamburg
country: Germany
facility: Kooperatives Mammazentrum Hamburg Krankenhaus Jerusalem
city: Hamburg
country: Germany
facility: Praxis Harburger Ring
city: Hamburg
country: Germany
facility: Iorc-Innovation Onkologie& Research& Consulting Gmbh; Praxis Lerchenfeld Hamburg
city: Hamburg
country: Germany
facility: Dres. Sigrun Müller-Hagen Mathias Bertram und Ulrich Stein
city: Hameln
country: Germany
facility: SANA Klinikum Hameln-Pyrmont; Frauenklinik / Brustzentrum
city: Hannover
country: Germany
facility: Diakovere Henriettenstift, Frauenklinik
city: Hannover
country: Germany
facility: Medizinische Hochschule Zentrum Frauenheilkunde Abt.Gynäkologische Onkologie
city: Herne
country: Germany
facility: Stiftung Kathol. Krankenhaus Marienhospital Herne Klinik Mitte Frauenklinik
city: Homburg/Saar
country: Germany
facility: Universitaetsklinikum des Saarlandes; Klinik f. Frauenheilkunden und Geburtshilfe
city: Jena
country: Germany
facility: Universitätsklinikum Jena; Klinik und Poliklinik für Frauenheilkunde und Fortpflanzungsmedizin
city: Kaiserslautern
country: Germany
facility: Westpfalz-Klinikum GmbH; Klinik für Frauenheilkunde und Geburtshilfe
city: Kassel
country: Germany
facility: Gemeinschaftspraxis Dr. Siehl & Dr. Soeling
city: Kiel
country: Germany
facility: Systemedic Frauenarzte Pruener Gang
city: Köln
country: Germany
facility: Gemeinschaftspraxis Für Haematologie/Onkologie
city: Köln
country: Germany
facility: Uniklinik Köln; Klinik Für Frauenheilkunde
city: Langen
country: Germany
facility: Asklepios Klinik; Abt. Gynäkologie
city: Lemgo
country: Germany
facility: Klinik Lippe Lemgo; Medizinische Klinik II/Haematoonkologie
city: Lübeck
country: Germany
facility: Universitätsklinikum Schleswig-Holstein / Campus Lübeck; Klinik für Frauenheilkunde und Geburtshilfe
city: Magdeburg
country: Germany
facility: Onkologische Gemeinschaftspraxis
city: Mainz
country: Germany
facility: Universitätsmedizin Mainz; Klinik u. Poliklinik f. Geburtshilfe u. Frauenheilkunde
city: Marburg
country: Germany
facility: Universitätsklinikum Marburg; Gynäkologie
city: Mülheim
country: Germany
facility: Ev. Krankenhaus
city: Münster
country: Germany
facility: Gemeinschaftspraxis für Hämatologie und Onkologie
city: Oldenburg
country: Germany
facility: Praxis Für Haematologie & Onkologie Dr. B. Otremba
city: Oranienburg
country: Germany
facility: Praxis Frau Dr. Schwarz
city: Passau
country: Germany
facility: Klinikum Passau; 2. Medizinische Klinik; Onkologie und Hämatologie
city: Rheinfelden
country: Germany
facility: Krankenhaus Rheinfelden; Frauenklinik
city: Rotenburg-wuemme
country: Germany
facility: Agaplesion Diakonieklinikum Rotenburg
city: Saarbruecken
country: Germany
facility: Caritas Klinik St. Theresia -Frauenklinik Brustzentrum
city: Saarbruecken
country: Germany
facility: Praxis Dr. Wagner
city: Saarbruecken
country: Germany
facility: Klinik Saarbrücken Ggmbh; Brustzentrum
city: Saarlouis
country: Germany
facility: DRK Krankenhaus Saarlouis; Kooperatives Brustzentrum
city: Saint Wendel
country: Germany
facility: Marienkrankenhaus Abt. Gynäkologie und Geburtshilfe
city: Stade
country: Germany
facility: MVZ für Hämatologie, Onkologie, Strahlentherapie und Palliativmedizin -; Klinik Dr. Hancken
city: Stendal
country: Germany
facility: Johanniter-Krankenhaus
city: Stralsund
country: Germany
facility: Klinik Der Hansestadt Stralsund Gmbh; Frauenklinik
city: Traunstein
country: Germany
facility: Klinikum Traunstein
city: Trier
country: Germany
facility: Klinikum Mutterhaus der Borromaeerinnen gGmbH; Haematologie/Onkologie
city: Unna
country: Germany
facility: Katharinen-Hospital gGmbH
city: Weiden
country: Germany
facility: Kliniken Nordoberpfalz; Klinikum Weiden; Brustzentrum
city: Wiesbaden
country: Germany
facility: Gemeinschaftspraxis Hämatologie / Onkologie
city: Budapest
country: Hungary
facility: Semmelweis Egyetem Onkologiai Központ
city: Budapest
country: Hungary
facility: Municipal Hospital of Uzsoki Utca; Centre of Oncoradiology
city: Nyíregyháza
country: Hungary
facility: Josa Andras Korhaz; Dept of Oncoradiology
city: Szombathely
country: Hungary
facility: Vas Megyei Markusovszky Korhaz ; Pulmonology
city: Chieti
country: Italy
facility: Policlinico Ospedaliero Ss Annunziata; U.O. Di Clinica Oncologica
state: Abruzzo
city: Potenza
country: Italy
facility: Ospedale San Carlo; Day Hospital Oncologia Medica
state: Basilicata
city: Rionero in Vulture
country: Italy
facility: Ospedale Oncologico Regionale; U.O. Oncologia Medica Ed Ematologia
state: Basilicata
city: Catanzaro
country: Italy
facility: Az. Osp. Pugliese; Dh Oncologico
state: Calabria
city: Cosenza
country: Italy
facility: Az. Osp. Mariano Santo; Centro Oncologico
state: Calabria
city: Avellino
country: Italy
facility: Azienda Ospedaliera S.G. Moscati; Division of Medical Oncology
state: Campania
city: Napoli
country: Italy
facility: Az. Osp. Cardarelli; Divisione Di Oncologia
state: Campania
city: Napoli
country: Italy
facility: Ist. Uni Federico Ii; Divisione Di Oncologia Medica - Dpt. Di Medicina Interna
state: Campania
city: Napoli
country: Italy
facility: Istituto Tumori Fondazione Pascale; Endocrinologia Oncologica
state: Campania
city: Napoli
country: Italy
facility: Ospedale S. Gennaro; Oncologia Medica
state: Campania
city: Bologna
country: Italy
facility: Az. Osp. S. Orsola Malpighi; Istituto Di Oncologia Seragnoli
state: Emilia-Romagna
city: Meldola
country: Italy
facility: Opspedale Morgagni - Pierantoni; Dept. Di Oncologia Medica
state: Emilia-Romagna
city: Ravenna
country: Italy
facility: Ospedale Provinciale Santa Maria delle Croci
state: Emilia-Romagna
city: Aviano
country: Italy
facility: Irccs Centro Di Riferimento Oncologico (CRO); Dipartimento Di Oncologia Medica
state: Friuli-Venezia Giulia
city: Trieste
country: Italy
facility: Centro Soc. Oncologico, Azienda Sanitaria Universitaria Integrata Trieste; CENTRO ONCOLOGICO
state: Friuli-Venezia Giulia
city: Latina
country: Italy
facility: Ospedale S. Maria Goretti; Divisione Di Oncologia Medica
state: Lazio
city: Roma
country: Italy
facility: Ospedale San Giacomo in Augusta; Reparto Oncologia
state: Lazio
city: Roma
country: Italy
facility: Policlinico Universitario Campus Biomedico; Uoc Oncologia Medica
state: Lazio
city: Roma
country: Italy
facility: Azienda Complesso Ospedaliero S. Filippo Neri; Divisione Di Oncologia Medica
state: Lazio
city: Roma
country: Italy
facility: Istituto Regina Elena; Oncologia Medica A
state: Lazio
city: Roma
country: Italy
facility: Policlinico Militare Di Roma; Reparto Di Oncologia
state: Lazio
city: Genova
country: Italy
facility: IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A
state: Liguria
city: La Spezia
country: Italy
facility: Ospedale S. Andrea Est Felettino; Oncologia Medica
state: Liguria
city: Bergamo
country: Italy
facility: Asst Papa Giovanni XXIII; Oncologia Medica
state: Lombardia
city: Brescia
country: Italy
facility: Az. Osp. Spedali Civili; Divisione Di Oncologia - Iii Medicina
state: Lombardia
city: Casalpusterlengo
country: Italy
facility: Ospedale Di Casalpusterlengo; Day Hospital Oncologico
state: Lombardia
city: Como
country: Italy
facility: Ospedale Valduce; Dept. Di Oncologia Medica
state: Lombardia
city: Lecco
country: Italy
facility: ASST DI LECCO; Oncologia Medica
state: Lombardia
city: Legnano
country: Italy
facility: ASST OVEST MILANESE; Oncologia Medica
state: Lombardia
city: Mantova
country: Italy
facility: Az. Osp. Carlo Poma; Divisione Di Oncologia Medica
state: Lombardia
city: Milano
country: Italy
facility: Istituto Europeo Di Oncologia
state: Lombardia
city: Milano
country: Italy
facility: Asst Santi Paolo E Carlo; Unita Operativa Di Oncologia Medica
state: Lombardia
city: Pavia
country: Italy
facility: Fondazione Salvatore Maugeri; Divisione Di Oncologia Medica
state: Lombardia
city: Pavia
country: Italy
facility: Fondazione Salvatore Maugeri; Servizio Di Prevenzione Oncologica
state: Lombardia
city: Pavia
country: Italy
facility: Irccs Policlinico S. Matteo - Uni Pavia; Clinica Medica I Div. Med. Int. Onc. Medica E Gastroent.
state: Lombardia
city: Varese
country: Italy
facility: Ospedale Di Circolo; Centro Di Senologia
state: Lombardia
city: Fano
country: Italy
facility: Ospedale S. Croce Di Fano; Servizio Oncologia
state: Marche
city: Candiolo
country: Italy
facility: Fondazione Del Piemonte Per L'oncologia Ircc Di Candiolo; Dipartimento Oncologico
state: Piemonte
city: Ponderano (BI)
country: Italy
facility: Ospedale Degli Infermi Di Biella; Reparto Oncologia Medica
state: Piemonte
city: Torino
country: Italy
facility: A.O. Città della Salute e della Scienza - Presidio Molinette; divisione oncologia medica
state: Piemonte
city: Torino
country: Italy
facility: Ospedale Sant'Anna - Uni Di Torino; Unita Di Oncologia Ginecologica
state: Piemonte
city: Lecce
country: Italy
facility: Ospedale Vito Fazzi; Div. Oncoematologia
state: Puglia
city: San Giovanni Rotondo
country: Italy
facility: IRCCS Ospedale Casa Sollievo Della Sofferenza; Oncologia
state: Puglia
city: Cagliari
country: Italy
facility: A.O.U. Cagliari-P.O. Monserrato;U.O. Oncologia
state: Sardegna
city: Sassari
country: Italy
facility: Azienda Ospedaliero Universitaria Di Sassari;Oncologia
state: Sardegna
city: Catania
country: Italy
facility: Centro Catanese Di Oncologia; Oncologia Medica
state: Sicilia
city: Palermo
country: Italy
facility: Az. Osp. M. Ascoli G. Di Cristina; Oncologia Medica
state: Sicilia
city: Palermo
country: Italy
facility: La Maddalena Casa Di Cura Di Alta Specialita; Oncologia Chirurgica
state: Sicilia
city: Ragusa
country: Italy
facility: Az. Osp. ; Divisione Di Oncologia
state: Sicilia
city: Arezzo
country: Italy
facility: USL 8 Ospedale San Donato; Oncology Endocrinology
state: Toscana
city: Bagno a Ripoli
country: Italy
facility: Ospedale Santa Maria Annunziata; Oncologia
state: Toscana
city: Firenze
country: Italy
facility: Azienda Ospedaliero-Universitaria Careggi;S.C. Oncologia Medica 1
state: Toscana
city: Lucca
country: Italy
facility: Ospedale Campo Di Marte; Dipartimento Oncologico
state: Toscana
city: Poggibonsi
country: Italy
facility: Azienda Usl 7; Dept. Oncologico
state: Toscana
city: Trento
country: Italy
facility: Ospedale Santa Chiara; Oncologia Medica
state: Trentino-Alto Adige
city: Cona (Ferrara)
country: Italy
facility: Arcispedale S.Anna; Oncologia Medica
state: Veneto
city: Santorso
country: Italy
facility: Polo Ospedaliero Santorso
state: Veneto
city: Vicenza
country: Italy
facility: Ospedale Civile S. Bortolo; Divisione Di Oncologia
state: Veneto
city: Bydgoszcz
country: Poland
facility: Regionalne Centrum Onkologi; Oddzial Chorob Wewnetrznych I Onkologii
city: Poznan
country: Poland
facility: Oddzial Chemioterapii Szpitala Klinicznego Nr 1 w Poznaniu
city: Mataro
country: Spain
facility: Hospital General de Mataro; Servicio de Oncologia
state: Barcelona
city: Sabadell
country: Spain
facility: Corporacio Sanitaria Parc Tauli; Servicio de Oncologia
state: Barcelona
city: La Laguna
country: Spain
facility: Hospital Universitario de Canarias;servicio de Oncologia
state: Tenerife
city: Jaen
country: Spain
facility: Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia
city: Malaga
country: Spain
facility: Hospital Regional Universitario Carlos Haya
city: Navarra
country: Spain
facility: Hospital de Navarra; Servicio de Oncologia
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen del Rocio; Servicio de Oncologia
city: Toledo
country: Spain
facility: Complejo Hospitalario de Toledo- H. Virgen de la Salud; Servicio de Oncologia
city: Zaragoza
country: Spain
facility: Hospital Universitario Miguel Servet; Servicio Oncologia
city: Gaevle
country: Sweden
facility: Gävle sjukhus onkologkliniken
city: Jonkoping
country: Sweden
facility: Lanssjukhuset Ryhov; Onkologkliniken
city: Kalmar
country: Sweden
facility: Länssjukhuset Kalmar; Oncology
city: Karlstad
country: Sweden
facility: Centralsjukhuset Karlstad, Onkologkliniken
city: Linköping
country: Sweden
facility: Uni Hospital Linkoeping; Dept. of Oncology
city: Lund
country: Sweden
facility: Skånes University Hospital, Skånes Department of Onclology
city: Stockholm
country: Sweden
facility: Karolinska Hospital; Oncology - Radiumhemmet
city: Sundsvall
country: Sweden
facility: Länssjukhuset Sundsvall, Onkologkliniken
city: Umea
country: Sweden
facility: Norrlands Universitetssjukhus, Umeå, Cancercentrum; Dept of Oncology
city: Aberdeen
country: United Kingdom
facility: Aberdeen Royal Infirmary; Medical Oncology Dept
city: Belfast
country: United Kingdom
facility: Belfast City Hospital; Dept of Oncology
city: Cardiff
country: United Kingdom
facility: Velindre Cancer Centre; Oncology Dept
city: Chelmsford
country: United Kingdom
facility: Broomfield Hospital; Oncology
city: Dundee
country: United Kingdom
facility: Ninewells Hospital; Dept of Radiotherapy & Oncology
city: Exeter
country: United Kingdom
facility: Royal Devon & Exeter Hospital; Oncology Centre
city: Glasgow
country: United Kingdom
facility: Glasgow Western Infirmary; Dept of Radiotherapy
city: Huddersfield
country: United Kingdom
facility: Huddersfield Royal Infirmary
city: Kings Lynn
country: United Kingdom
facility: Queen Elizabeth Hospital
city: London
country: United Kingdom
facility: St Thomas Hospital; Medicine Div.
city: London
country: United Kingdom
facility: St George'S Hospital; Oncology Research Office /Oncology Opd
city: London
country: United Kingdom
facility: Charing Cross Hospital; Medical Oncology.
city: Manchester
country: United Kingdom
facility: Christie Hospital; Breast Cancer Research Office
city: Middlesborough
country: United Kingdom
facility: James Cook Uni Hospital
city: Newcastle Upon Tyne
country: United Kingdom
facility: Newcastle General Hospital
city: Preston
country: United Kingdom
facility: Royal Preston Hosptial
city: Romford
country: United Kingdom
facility: Oldchurch Hospital
city: Salisbury
country: United Kingdom
facility: Salisbury District General Hospital; Medical Oncology Dept
city: Shrewsbury
country: United Kingdom
facility: Royal Shrewsbury Hospitals Nhs Trust; Oncology
city: Southampton
country: United Kingdom
facility: Southampton General Hospital; Medical Oncology
city: Worthing
country: United Kingdom
facility: Worthing Hospital; Sussex Oncology Centre, Worthing Breast Unit
city: Yeovil
country: United Kingdom
facility: Yeovil District Hospital; Macmillan Cancer Unit
city: York
country: United Kingdom
facility: Airedale General Hospital; Oncology
Study officials:
affiliation: Hoffmann-La Roche
name: Clinical Trials
role: STUDY_DIRECTOR
References: