Clinical trial NCT02579109: Multisensorial Information's Treatment in Autism Spectrum Disorder
Official title: Exploring Social Cognition in Autism Spectrum Disorder With Long Time Memory Task. Controlled Study on 8-13 Years Childs
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Autism
Lead sponsor: Centre Hospitalier Universitaire de Nice
Sponsor class: OTHER
First posted: 2015-10-19
Enrollment: 38
Sex: ALL
Minimum age (years): 7
Maximum age (years): 13
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: Introduction:

Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors. There's also deficits in social cognition. When having a face-to-face conversation, a listener not only hears what a speaker is saying, but also sees the articulatory gestures that accompany those sounds. Speech signals needs then a multisensory processing. Impairments in multisensory perceptual binding may be particularly relevant in ASD, given that hallmark features of the disorder include difficulties in speech, communication, and social interactions.

Objectives:

The investigator suggest that atypical multisensory processing in ASD may have an impact on speech perception and social processing.

Aims:

Methods:

This pilot study measures free recall scores in 3 lists of words presentation after 30 minutes. In the first condition (CI) words are only listening. In the second condition (CII) words are associated with a picture of a mans face. In the third condition (CIII) words are associated with a video of a man speaking. Three lists are homogeneous form words characteristics (lexical frequency, emotional valence norm, imageability). Participants were 7- to 13-year-olds typically developing children (TD) (N = 19) and ASD children (N = 19).

The investigator would create some new tools for exploring the treatment of a social information. These tools should be the closest of a ecological social interaction.


Eligibility criteria: Inclusion Criteria:

* Boy or girl,
* 7 - 13 years,
* Presenting a diagnosis DSM IV of disorder(confusion) of the autistic spectre: detected by the scale(ladder) ADI ( Autism Diagnostic Interview) or by TEENAGERS (Autism Diagnostic Observation Schedule): typical autistic. These patients do not answer the diagnosis of psychosis according to Kiddie-SADS,
* Upper total IQ or equal to 50, examination dating less than year before the inclusion,
* French-speaking children,
* Signature of the informed consent by the parents(relatives) and the child,
* Membership to the Social Security.

Exclusion Criteria:

* Genetic, neurological or neurosensory pathologies,
* Diagnosis of intrusive disorder(confusion) of the not specified development: TED our,
* The patients will not be included who would participate in a program or a study of reeducation in the social fitnesses.

Primary outcomes:
measure: rate of reminder after 30 minutes between the group autistic and the group witness( %)
timeFrame: 30 minutes
Secondary outcomes:
measure: Difference of the scores of reminders words (%)
timeFrame: 30 minutes
Other outcomes:
Locations:
Study officials:
References: