Clinical trial NCT05353218: Ultrasound-Guided Intermediate Versus Deep Cervical Plexus Block for Carotid Endarterectomy
Official title: Efficacy of Ultrasound-Guided Intermediate Versus Deep Cervical Plexus Block for Carotid Endarterectomy: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anesthesia
Keywords: cervical plexus block
Endarterectomy, Carotid
Lead sponsor: Istanbul University
Sponsor class: OTHER
First posted: 2022-04-29
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized, Prospective
Primary purpose: TREATMENT

Brief summary: Cervical plexus blocks are regional methods used in carotid endarterectomy. Cervical plexus blocks consist of three blocks: superficial, intermediate and deep. These three blocks can be used alone or combined. The aim of this study is to evaluate the effectiveness of ultrasound-guided intermediate and deed cervical plexus block in patients undergoing carotid endarterectomy.

Detailed description: Carotid endarterectomy is a surgical method used to treat occlusive lesions of the carotid. Regional anesthesia is preferred because it allows for consciousness control and neurological examination during the operation. Cervical plexus blocks are regional methods used in carotid endarterectomy. It is a regional technique in which the cervical spinal nerves (C2-C3-C4) are blocked with a local anesthetic agent from different regions. Cervical plexus blocks consist of three blocks: superficial, intermediate and deep, depending on the depth at which the local anesthetic agent is infiltrated. According to the preference of the clinician for the purpose of anesthesia, these three blocks can be used separately or combined. It is mentioned that all three blocks provide sufficient anesthesia for carotid endarterectomy surgery to be performed.

In the study, investigators planned to evaluate the effectiveness of ultrasound-guided intermediate and deep cervical plexus blocks in patients undergoing carotid endarterectomy by comparing the number of patients who need additional local anesthetics.

Eligibility criteria: Inclusion Criteria:

* Patients scheduled for carotid endarterectom y surgery.

Exclusion Criteria:

* Local infection
* Previous ipsilateral surgery
* Radiotherapy
* Conversion to general anesthesia
* Known bleeding disorders
* Known allergy of local anesthetic

Primary outcomes:
measure: Number of patient needed supplemental local anesthetic
timeFrame: Intraoperative 2-3 hours
Secondary outcomes:
measure: Amount of supplemental local anesthetic
timeFrame: Intraoperative 2-3 hours
measure: Duration of blocks' application
timeFrame: Up to 15 minutes
measure: Region where patient needs supplemental local anesthetic
timeFrame: Intraoperative 2-3 hours
measure: Amount of remifentanil
timeFrame: Intraoperative 2-3 hours
measure: Pain assessment
timeFrame: Intraoperative 2-3 hours
measure: Complications
timeFrame: Up to 24 hours
measure: Patient's satisfaction
timeFrame: Up to 24 hours
measure: Surgeon's satisfaction
timeFrame: Up to 24 hours
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Faculty of Medicine
Study officials:
References: