Clinical trial NCT04292106: The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance
Official title: The Effects of Red Spinach Extract Supplementation on Isometric Strength, Resistance Exercise and Cognitive Performance.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Sports
Lead sponsor: Lipscomb University
Sponsor class: OTHER
First posted: 2020-03-02
Enrollment: 11
Sex: MALE
Minimum age (years): 18
Maximum age (years): 34
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: Red Spinach is a natural food which is a rich source of nitrates, which are beneficial in hemodynamics, cardiovascular function, and have natural hypotensive and antianginal effects. Red spinach extract has been shown to be beneficial in exercise performance, albeit mostly in aerobic exercise. In a previous study in our lab, we found that dietary nitrate consumption resulted in significantly greater isometric force production in teenage males. However, currently there is little know regarding the effects of dietary nitrate supplementation on isometric strength, resistance exercise and cognitive performance.

Detailed description: This research study is designed to measure the effects of red spinach extract (RSE) on markers of physical and cognitive performance during and following anaerobic exercise.

Eligibility criteria: Inclusion Criteria:

* 18-34 years old Participants must have at least 1 year of resistance training experience.
* Free of any physical limitations, medications, and supplements that may affect performance, as determined by a health and activity questionnaire.
* Are free of musculoskeletal injuries
* Are not taking medications that may interfere with study measurements

Exclusion Criteria:

* Participants that cannot take either the RSE or placebo supplement will be excluded, as this will be a double-blind study.
* Furthermore, participants that cannot participate in pre- and post-research testing, and/or those that cannot commit to regular training sessions will be excluded.
* Inability to perform physical exercise (determined by health and activity questionnaire)
* Taking any other nutritional supplement or performance enhancing drug.
* Any chronic illness that causes continuous medical care

Primary outcomes:
measure: Bench Press Repetitions to Fatiuge
timeFrame: Through study completion, during both treatments (~4 weeks)
measure: Bench Press Power
timeFrame: Through study completion, during both treatments (~4 weeks)
measure: Isometric Mid-thigh pull (IMTP) Peak Force
timeFrame: Through study completion, during both treatments (~4 weeks)
measure: Isometric Mid-thigh pull (IMTP) Rate of Force Development
timeFrame: Through study completion, during both treatments (~4 weeks)
Secondary outcomes:
measure: Estimated Muscle Blood Flow via Near-infrared Spectroscopy (NIRS)
timeFrame: Through study completion, during both treatments (~4 weeks)
measure: Cognitive Performance via Stroop Test
timeFrame: Through study completion, during both treatments (~4 weeks)
Other outcomes:
Locations:
city: Nashville
country: United States
facility: Jeremy Townsend
state: Tennessee
Study officials:
affiliation: Lipscomb University
name: Jeremy Townsend, PhD
role: PRINCIPAL_INVESTIGATOR
References: