Clinical trial NCT05173636: Effects of Cervical Lateral Glide Along With Thoracic Mobilizations in Patients With Neurogenic Cervicobrachial Pain.
Official title: Effects of Cervical Lateral Glide Mobilizations Along With Thoracic Mobilizations in Patients With Neurogenic Cervicobrachial Pain.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cervicobrachial Syndrome
Keywords: Pain
Range of motion
Cervicobrachial pain
Cervical lateral glide
Thoracic mobilization
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-12-30
Enrollment: 30
Sex: ALL
Minimum age (years): 25
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: In the scientific literature, cervicobrachial pain is the presence of pain in the neck that radiates or refers to the arm. It is considered as common spine disorder with upper quadrant pain due to muscles, joints or intervertebral discs. This study aims to compare the effects of direct neural tissue technique that is cervical lateral glide mobilization along with indirect neural tissue mobilization technique that is thoracic mobilization on pain, range of motion, endurance of neck flexors and functional ability in patients with cervicobrachial pain.

Detailed description: The exact incidence of cervicobrachial pain syndrome is not known due to the paucity of population-based studies, patients suffering the symptoms of this condition frequently attend for physiotherapy.

In the scientific literature, cervicobrachial pain is the presence of pain in the neck that radiates or refers to the arm. It is considered as common spine disorder with upper quadrant pain due to muscles, joints or intervertebral discs. Upper quadrant discomfort involves neck, shoulder, arm, upper back but neural tissue sensitivity to mechanical stimuli portrays to be the essential element of cervicobrachial pain. It generally refers to neck pain that along with paresthesia is radiating to one upper extremity and leading to muscle imbalances. Elvey planned some clinical tests to recognize the problems of neurogenic disorders that are responsive to non-intrusive physical therapy treatment. The acceptability of these tests from effective treatments has not been adequately proven yet.

According to the literature cervical lateral glide is considered as first line treatment in reducing pain and improving upper limb function and is specifically very effective in patients of cervicobrachial pain syndrome. Cervical lateral glide has hypoalgesic effect on neck and arm pain. It is thought that this technique stimulates cervical afferents which can affect pain processes at spinal cord and cortical levels. A study was conducted in which passive techniques for mobilizing neural tissue and cervical spine were given as direct manual therapy treatment. Thoracic mobilization corresponds to indirect neural mobilization that is effective in reducing pain and functional limitations when incorporated with cervical spine mobilization that is referred as direct neural mobilization in patients of cervicobrachial pain. Evidence suggests that improvement in cervical stability and thoracic mobility achieved through manual therapy is significant in reducing neck pain and improving functional motion This study would help to investigate the delineation between specific and non-specific components of manual therapy. This study aims to compare the effects of direct neural tissue technique that is cervical lateral glide mobilization along with indirect neural tissue mobilization technique that is thoracic mobilization on pain, range of motion, endurance of neck flexors and functional ability in patients with cervicobrachial pain.

Eligibility criteria: Inclusion Criteria:

* Pain in upper quadrant associated with cervical spine eliciting unilateral neck pain.
* Paresthesia and numbness in the neck and arm for at least three continuous months
* Active movements of cervical spine (extension, lateral flexion to either side or ipsilateral rotations) and arm movements reproducing pain.
* Symptom reproduction on passive movements in the same pattern as with active movements.
* Elicitation of adverse response (in terms of range of movement and reproduction of symptoms) to neural tissue provocation testing of median, ulnar and radial nerves and subsequent symptom alteration with neural tissue differentiating maneuvers.
* Tenderness at transverse processes of cervical spine (nerve roots), nerve trunks of median, ulnar and radial nerves at different anatomical locations in the course of respective neural tissue.
* Hyperalgesic related cutaneous tissues on palpation (tender points).
* Evidence of a related pathology (example: radiological evidence of cervical disc pathology in the vicinity of involved nerve roots or evidence of stenosis at cervical neural foramen as diagnosed by a qualified musculoskeletal Radiologist)
* provoked or spontaneous paresthesia and pain with radicular distribution
* Positive results in the following tests: Spurling, Distraction, and Upper Limb tension test.
* Diagnosis will be based upon subjective presentation of patient's pain pattern which includes somatic referred pain and neurogenic radiating symptoms.

Exclusion Criteria:

* Bilateral symptoms (due to unilateral nature of lateral glide mobilization technique).
* History of spinal surgery
* Systemic diseases besides neck pain.
* Vertebral infections.
* Presented red flags.
* Used analgesics within 48 hours before initial assessment.

Primary outcomes:
measure: Numeric pain rating scale for pain
timeFrame: at base line
measure: Numeric pain rating scale for pain
timeFrame: at 2nd week
measure: Numeric pain rating scale for pain
timeFrame: at 4th week
measure: Northwick Park neck pain questionnaire (for physical function)
timeFrame: at baseline
measure: Northwick Park neck pain questionnaire (for physical function)
timeFrame: at 2nd week
measure: Northwick Park neck pain questionnaire (for physical function)
timeFrame: at 4th week
measure: Cervical range of motion by Goniometer
timeFrame: at baseline
measure: Cervical range of motion by Goniometer
timeFrame: at 2nd week
measure: Cervical range of motion by Goniometer
timeFrame: at 4th week
measure: Deep neck flexor endurance test
timeFrame: at baseline
measure: Deep neck flexor endurance test
timeFrame: at 2nd week
measure: Deep neck flexor endurance test
timeFrame: at 4th week
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Benazir Bhutto Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: maria khalid, MS OMPT
role: PRINCIPAL_INVESTIGATOR
References: