Clinical trial NCT03928613: Efficacy of the Cognitive Training Based on Location Information and Activity in People With Mild Cognitive Impairment
Official title: Efficacy of the Cognitive Training Based on Location Information and Activity in People With Mild Cognitive Impairment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Mild Cognitive Impairment
Keywords: Cognitive training
Cognitive intervention
Cognitive rehabilitation
Lead sponsor: Seoul National University Bundang Hospital
Sponsor class: OTHER
Collaborators: name: Institute of Information & Communications Technology Planning & Evaluation, Korea
First posted: 2019-04-26
Enrollment: 43
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to examine therapeutic efficacy of cognitive Training based on location information and activity in people with mild cognitive impairment

Detailed description: * A single arm, open-label study.
* Cognitive Training based on location information and activity is consists of both cognitive training and exercise(walking) using objects in the participant's home. The researchers visit the participant's home and find objects that were mainly used in the real life and easy to access (table, computer, television, etc.) and attach the recognition Bluetooth Low Energy(BLE) Tag (sticker integrated). The stickers printed on the tags consist of word categories (eg animals) belonging to a particular category, so as to assist strategic recall in the stepped recall task. The participants follow the instruction from the tablet-based program to perform the task. During performing the cognitive training program, the participants are guided to walk between the tagged objects in their home.
* The participants are aged over 60 years old and diagnosed with mild cognitive impairment.

Eligibility criteria: Inclusion Criteria:

* Aged above 60
* Confirmed literacy o Diagnosed with mild cognitive impairment by International Working Group on Mild Cognitive Impairment and Clinical Dementia Rating(CDR) of 0 or 0.5.

Exclusion Criteria:

* Evidence of delirium, confusion
* Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus
* Evidence of severe cerebrovascular pathology
* Presence of depressive symptoms that could influence cognitive function
* Presence of medical comorbidities that could result in any difficulties in study participation

Primary outcomes:
measure: Change in CERAD-TS1 score
timeFrame: baseline and 6 weeks
Secondary outcomes:
measure: Change in MMSE score
timeFrame: baseline and 6 weeks
measure: Change in SMCQ score
timeFrame: baseline and 6 weeks
measure: Change in GDS score
timeFrame: baseline and 6 weeks
Other outcomes:
Locations:
city: Seongnam-si
country: Korea, Republic of
facility: Seoul National University Bundang Hospital,
state: Gyeonggi
Study officials:
affiliation: Seoul National University Bundang Hospital
name: Ji Won Han, M.D., Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: