Clinical trial NCT01750047: A Epidemiological Survey of Preoperative Pain Perception and Postoperative Pain in Chinese Population
Official title: A Epidemiological Survey of Preoperative Pain Perception and Postoperative Pain in Chinese Population
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pain
Surgery
Keywords: pain perception
postoperative pain
demography
smoking
alcohol
Lead sponsor: Huazhong University of Science and Technology
Sponsor class: OTHER
First posted: 2012-12-17
Enrollment: 1327
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Chinese patients receiving elective surgery under general anesthesia

Brief summary: Object: Every person's pain perception and possible postoperative pain is different. As the investigators know, they are affected by many factors. However, the investigators don't know whether the smoking factors, alcohol factors, surgery type, education background, etc. will affect individual pain perception and possible postoperative pain in Chinese population. This study was conducted to investigate the power of these possible affect factors. Method: Patients receiving elective surgery under general anesthesia were recruited into this study. The investigators measured their preoperative pressure pain threshold (PPT) and pressure pain tolerance (PTO)and also investigated the patient's personal information of smoking factors, alcohol factors, surgery type, education background, etc. In addition, we retrospectively investigated the visual analog scale (VAS) during patient-controlled analgesia (PCA) treatment 0 to 48 h after operation as well as the PCA press frequency and drug consumption of those patients who received PCA administration.

Detailed description: Patients with the following diseases were excluded: known history of chronic pain, psychiatric diseases or communication disorders, diabetes mellitus, severe cardiovascular diseases, kidney or liver diseases with poor hepatic function, alcohol or pregnancy or at the lactation period.

Eligibility criteria: Inclusion Criteria:

* Aged 18 to 70
* The right hand is handedness
* Agreed to participate the research
* Not with known chronic disease
* Not taking analgesics within 3 months

Exclusion Criteria:

* History of chronic pain diseases
* Diabetes mellitus
* Severe cardiovascular diseases
* Kidney or liver diseases
* Alcohol or drug abuse
* Pregnancy or at lactation period
* Disagree to participate to the research

Primary outcomes:
measure: Pressure pain threshold
timeFrame: 1 year
measure: Pressure pain tolerance
timeFrame: 1 year
Secondary outcomes:
measure: Pain scores on visual analog scale after operation
timeFrame: 1 year
measure: Opioid consumption dose after operation
timeFrame: 1 year
Other outcomes:
Locations:
city: Wuhan
country: China
facility: Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
state: Hubei
Study officials:
affiliation: Huazhong University of Science and Technology
name: Zhang Xianwei, Doctor
role: PRINCIPAL_INVESTIGATOR
References: