Clinical trial NCT06657599: Malnutrition is a Severe Health Issue for Cancer Patients. This Study Examines How Preoperative Nutritional Status Affects Postoperative Delirium in Patients Undergoing Major Abdominal Surgery for Gynecological and Gastrointestinal Tumors.
Official title: Malnutrition is a Severe Health Issue for Cancer Patients. This Study Examines How Preoperative Nutritional Status Affects Postoperative Delirium in Patients Undergoing Major Abdominal Surgery for Gynecological and Gastrointestinal Tumors. the Study Highlights the Critical Role of Preoperative Malnutrition in Delirium and Recommends That All Patients Scheduled for Major Abdominal Surgery Be Evaluated for Nutritional Status At the Outset.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Surgery
Malnutrition
Delirium, Postoperative
Abdominal Neoplasm
Lead sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Sponsor class: OTHER
First posted: 2024-10-24
Enrollment: 120
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients undergoing major abdominal surgery, have gynecological and GIS tumor, expected to stay in postoperative care unit for more than 24 hours.

Brief summary: The World Health Organization (WHO) identifies malnutrition as a significant public health threat. It is a common issue among cancer patients due to various factors. Specific nutrient deficiencies can lead to severe cognitive problems. This study aims to evaluate the impact of preoperative nutritional status on the frequency of postoperative delirium. Additionally, we will compare different parameters that can be used to diagnose preoperative malnutrition.

We included a total of 120 patients aged over 18 years, classified as ASA I-IV, who were undergoing major abdominal surgery for gynecological or gastrointestinal tumors and were expected to remain in the postoperative care unit for more than 24 hours. The patients' preoperative scores, albumin levels, prealbumin levels, and other relevant data were recorded. In the first 24 hours post-surgery, delirium was assessed using the Ramsay Sedation Scale and the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU).


Eligibility criteria: Inclusion Criteria:

* ASA I-IV
* Over 18 years of age
* Undergoing major abdominal surgery for gynecological and GIS tumor
* Expected to stay in postoperative care unit for more than 24 hours

Exclusion Criteria:

* Under age 18.
* Patients scheduled for emergency surgery, pregnancy, who want to withdraw from postoperative work.
* Patients with dementia, Alzheimer, psychiatric illness, illiterate people.
* Patients with speech, vision and hearing problems.
* Patients with a history of alcoholism.
* Patients who need postoperative mechanical ventilation support (patients who develop heart or respiratory failure due to COPD, heart failure, pulmonary embolism and similar reasons)

Primary outcomes:
measure: CAM-ICU
timeFrame: 24 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Ozlem Sen
Study officials:
References: