Clinical trial NCT00773799: Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community
Official title: Mastering Hospital Antimicrobial Resistance and Its Spread Into the Community
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: ESBL Infection
Methicillin-Resistant Staphylococcus Aureus
Keywords: To define activities and patient characteristics likely to lead to dissemination of resistant bacteria in rehabilitation centers and
To define specific risk factors for acquisition of resistant bacteria (ESBL producers and MRSA) in rehabilitation centers.
ESBL producers
MRSA
Lead sponsor: Tel-Aviv Sourasky Medical Center
Sponsor class: OTHER_GOV
First posted: 2008-10-16
Enrollment: 1200
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: A rehabilitation center's department in which the hospitalized patients are older then 18 years old.

Brief summary: Data on occurrence of antimicrobial resistant bacteria acquisition in rehabilitation centers will be collected. After removal of patient identifiers, information regarding the patients population will be entered into electronic sheet. The phase will last twelve months in each center.

Detailed description: All patients admitted to the department will be examined on admission, two weeks latter and monthly by obtaining nares and perirectal cultures. These cultures will be processed for detection the target organisms. This activity is part of the good medical practice and is performed on routine basis in various hospital units

Epidemiological data will be collected from patient records. This data will be stored after removal of all patients' identifiers. These data will be transferred for analysis to Tel Aviv Medical Center

Eligibility criteria: Inclusion Criteria:

* Hospitalized patients are older then 18 years old

Exclusion Criteria:

* Age 18 years or less

Primary outcomes:
measure: A rehabilitation center's department in which the hospitalized patients are older then 18 years old.
timeFrame: 1 YEAR
Secondary outcomes:
Other outcomes:
Locations:
city: Tel-aviv
country: Israel
facility: Tasmc
Study officials:
affiliation: TASMC
name: Yehuda carmeli, MD MPH
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Smith DL, Dushoff J, Perencevich EN, Harris AD, Levin SA. Persistent colonization and the spread of antibiotic resistance in nosocomial pathogens: resistance is a regional problem. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3709-14. doi: 10.1073/pnas.0400456101. Epub 2004 Feb 25.