Clinical trial NCT02506413: Replicating MamaToto in Rural Tanzania
Official title: Replicating MamaToto in Rural Tanzania
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Maternal Death
Newborn Death
Keywords: Maternal and Newborn Health
Lead sponsor: University of Calgary
Sponsor class: OTHER
Collaborators: name: Catholic University of Health and Allied Sciences
First posted: 2015-07-23
Enrollment: 8323
Sex: ALL
Minimum age (years): 15
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: This study was part of a longitudinal implementation evaluation using an effectiveness-intervention hybrid (Type 2) design and a RE-AIM evaluation model.
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This study aimed to adapt and implement a district-led, policy-based, low cost Maternal and Newborn Health (MNH) intervention package using the MamaToto process, proven successful in Uganda, in rural Tanzania. The investigators hypothesized that the 'MamaToto Package' will be successfully implemented in the Misungwi District and will be effective in improving key maternal and newborn health indicators of study participants.

Detailed description: This study collected baseline data on indicators related to pre-natal care, delivery, post-natal care, treatment of childhood illnesses and family planning. Data collection tools/strategies included 1) a mapping exercise, 2) health facility audit 3) household surveys and 4) exit interviews. Data was collected at baseline and endline. Operational data was collected throughout the life of the study. Results were used to inform implementation of interventions that aim to improve health facility capacity to deliver good quality care to women and children and to strengthen families and communities to better advocate for and engage in activities that promote healthier women and children.

Mapping data was collected in two districts 1) Misungwi and 2) Kwimba. Baseline and endline data was collected in Misungwi only. The intervention began in Misungwi in Years 1 and 2 and then rolled out to Kwimba in Year 3.

Eligibility criteria: Inclusion Criteria:

* Randomly selected households (30) living in selected hamlets with a competent participant of greater than 15 years of age
* All women of reproductive age (age 15-49 years old) living in selected households in selected hamlets

Exclusion Criteria:

* Households with participants that are away for an extended time or have no one home at the time of survey completion

Primary outcomes:
measure: Proportion of live births attended by a skilled health provider
timeFrame: Change between pre (baseline) and post (endline-up to 36 months) intervention
Secondary outcomes:
measure: Proportion of women receiving postnatal care <48H
timeFrame: Change between pre (baseline) and post (endline-up to 36 months) intervention
measure: Proportion of women receiving antenatal care 4 or more times during pregnancy
timeFrame: Change between pre (baseline) and post (endline-up to 36 months) intervention
Other outcomes:
Locations:
city: Mwanza
country: Tanzania
facility: Catholic University of Health and Allied Sciences
Study officials:
affiliation: Catholic University of Health and Allied Sciences
name: Dismas K Matovelo, MD, MMed
role: PRINCIPAL_INVESTIGATOR
References:
citation: Matovelo D, Boniphace M, Singhal N, Nettel-Aguirre A, Kabakyenga J, Turyakira E, Mercader HFG, Khan S, Shaban G, Kyomuhangi T, Hobbs AJ, Manalili K, Subi L, Hatfield J, Ngallaba S, Brenner JL. Evaluation of a comprehensive maternal newborn health intervention in rural Tanzania: single-arm pre-post coverage survey results. Glob Health Action. 2022 Dec 31;15(1):2137281. doi: 10.1080/16549716.2022.2137281.