Clinical trial NCT05514951: Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment
Official title: Study of the Prevalence of Iron Deficiency in Elderly Patient in Hospital Environment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Iron-deficiency
Lead sponsor: Vifor Pharma
Sponsor class: INDUSTRY
First posted: 2022-08-25
Enrollment: 888
Sex: ALL
Minimum age (years): 75
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: Iron deficiency is defined by insufficient tissue iron stores and anemia is the ultimate stage of iron deficiency. Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

Detailed description: Iron deficiency (MD) is defined by insufficient tissue iron stores. Since iron is essential for the synthesis of hemoglobin, when the iron deficiency no longer makes it possible to maintain a sufficient level of erythropoiesis, anemia appears: it is the ultimate stage of iron deficiency.

Anemia is the most common haematological pathology encountered in geriatric practice. Its prevalence, in population generally ambulatory, is between 10 and 15% after the age of 65 and is greater than 20% beyond the age of 85.

Anemia should never be neglected in an elderly subject because it is associated with an increase in mortality, but also with a increased morbidity in terms of complications heart disease, cognitive decline, frailty, hospitalizations, and impairment of quality of life. About a third of anemias elderly person is attributable to a deficiency in vitamin B9 or B12 or an iron deficiency.

Apart from anemia, iron deficiency is common and constitutes a factor of poor prognosis in diseases chronic such as heart failure, kidney failure chronic or cancer, all pathologies very frequently found in the elderly. It is the origin of the deterioration in the general condition of patients, their re-hospitalization or even the progression of their pathology.

In this context where elderly patients also present a certain number of comorbidities including the pathologies mentioned previously, it is important to better diagnose the deficiency martial in the elderly patient.

This diagnosis is all the more important because, depending on the chronic pathology, data from the literature have shown that correcting the iron deficiency brings benefits to the patient by reducing the risk of recurrence of anemia, the prescription of erythropoietin and the use of transfusion for patients in oncology, gastroenterology and nephrology

Eligibility criteria: Inclusion Criteria:

* Any patient hospitalized in a geriatric unit (short geriatric stay, SSR) or seen on an outpatient basis (hospitalization day, consultation)
* Affiliated patient or beneficiary of a social healthcare system
* Patient having given written consent

Exclusion Criteria:

* Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by court order or administration

Primary outcomes:
measure: Percentage of patients diagnosed with iron deficiency on inclusion
timeFrame: Day 1
Secondary outcomes:
Other outcomes:
Locations:
city: ANGERS Cedex 9
country: France
facility: Chu Angers
city: Bayonne
country: France
facility: CH de Bayonne
city: Calais Cedex
country: France
facility: Ch De Calais
city: Chambéry
country: France
facility: CH Chambéry
city: Corbeil-Essonnes
country: France
facility: CHSF
city: Dunkerque Cedex 1
country: France
facility: Ch de Dunkerque
city: Lille Cedex
country: France
facility: Hôpital Gériatrique Les Bateliers Chu Lille
city: Nantes Cedex 1
country: France
facility: Chu De Nantes, Hôpital Bellier
city: Nice
country: France
facility: CHU de NICE-hopital CIMIEZ
city: Paris Cedex 12
country: France
facility: Hopital Saint Antoine
city: Pau
country: France
facility: CH de Pau
city: Poitiers
country: France
facility: CHU de Poitiers
city: Strasbourg
country: France
facility: HUS - Hôpitaux Universitaires de Starsbourg
city: Tours Cedex 9
country: France
facility: Hôpital Bretonneau
city: Vandoeuvre-Lès-Nancy
country: France
facility: Chu Nancy
city: Villeurbanne
country: France
facility: HCL
Study officials:
References: