Clinical trial NCT04974606: Effect of Coffeeberry on Mood, Motivation and Cognitive Performance
Official title: Effect of Coffeeberry on Mood, Motivation and Cognitive Performance
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Fatigue, Mental
Alertness
Mood
Motivation
Cognitive Performance
Keywords: alertness
mental fatigue
coffeeberry
coffee fruit
Lead sponsor: PepsiCo Global R&D
Sponsor class: INDUSTRY
First posted: 2021-07-23
Enrollment: 30
Sex: ALL
Minimum age (years): 17
Maximum age (years): 50
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: The primary purpose is to test the short-term effects of the acute consumption of two novel beverages made from coffeeberries, the fruit of the coffee plant (Coffea arabica) benchmarked against caffeine on several aspects of cognitive performance.

Preliminary studies suggest that flavanols and chlorogenic acids can enhance cognitive performance. It is unknown if drinks formulated with flavanols and chlorogenic acids (without high sugar or caffeine) improve cognition or mood to a similar extent as caffeine. Coffeeberry beverage comparisons will be made to a flavored positive control beverage containing caffeine and a flavored placebo beverage.


Eligibility criteria: Inclusion Criteria:

* Are older than 17 and under 50 years of age
* Self-report of good health

Exclusion Criteria:

* Using any prescription medication including birth control
* Report hypersensitivity to caffeine
* Have visual impairment that cannot be corrected with glasses or contact lenses
* Report any food allergies
* Self-reported excessive leisure time physical activity (\> 7 strenuous bouts per week)
* the presence of current gastrointestinal, sleep, or psychiatric disorder,
* Report pregnancy/lactation, illegal drug use, smoker
* failure to demonstrate adequate minimal performance on lab, computer-based cognitive tasks.
* Participation in another clinical trial within past 30 days

Primary outcomes:
measure: Cognition score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Higher test scores are better.
measure: Fatigue score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Lower fatigue score is better.
measure: Alertness score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Higher alertness score is better.
measure: Calmness score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Higher calmness score is better.
measure: Contentedness score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Higher contentedness score is better.
measure: Motivation score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Higher motivation score is better.
measure: Energy score
timeFrame: Change from baseline to 60 and 120 min post-consumption. Stronger feelings of mental and physical energy are better.
Secondary outcomes:
Other outcomes:
Locations:
city: Athens
country: United States
facility: Exercise Psychology Laboratory University of Georgia
state: Georgia
Study officials:
affiliation: University of Georgia, Athens
name: Patrick J O'Connor
role: PRINCIPAL_INVESTIGATOR
References: