Clinical trial NCT06597552: The Effect of Inspiratory Muscle Training on Pediatric Cancer Patient
Official title: The Effect of Inspiratory Muscle Training on Respiratory Functions, Functional Capacity, Failure and Quailty of Life in Pediatric Cancer Patient
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pediatric Cancer
Inspiratory Muscle Training
Keywords: Pediatric Cancer
Inspiratory Muscle Training
Respiratory Function
Muscle Strength
Lead sponsor: Medipol University
Sponsor class: OTHER
Collaborators: name: Bezmialem Vakif University
First posted: 2024-09-19
Enrollment: 8
Sex: ALL
Minimum age (years): 8
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study is to examine the effects of inspiratory muscle training on respiratory functions, functional capacity, fatigue and quality of life in pediatric cancer patients who have recently completed treatment. A total of 27 patients were included in the study. The patients were divided into two groups as Training and Control groups. After the initial evaluation of all patients, they were included in an 8-week inspiratory muscle training program. The final evaluation was made at the end of 8 weeks. According to the final evaluations, it was found that there was a statistical increase in favor of the Training group on Maximal Inspiratory Pressure, 6 Minute Walking Test, Quality of Life and Fatigue.

Detailed description: The aim of this study is to investigate the effects of inspiratory muscle training on respiratory functions, functional capacity, fatigue and quality of life in pediatric cancer patients. A total of 27 patients, 13 in the training group and 14 in the control group, who received and completed cancer treatment at the Memorial Şişli Hospital Pediatric Oncology and Hematology Department and who met the inclusion criteria were included in the study. The age, gender, diagnosis, height and weight of the patients included in the study were recorded. Evaluations were made regarding respiratory functions, respiratory muscle strength, functional capacity, fatigue and quality of life in the patients before and after inspiratory muscle training.

In the study, the initial and post-training values of the FVC, % FVC, FEV1, % FEV1, FEV1/FVC, PEF and % PEF in the respiratory function test of the patients in the training and control groups were compared.

The MIP and MEP values of the patients in the training and control groups were compared with the initial and post-test values of SpO2, heart rate and walking distance calculated after 6MWT. Fatigue values of patients in the education and control groups before and after inspiratory muscle training were compared. Physical, emotional, social and school-related baseline values obtained after the pediatric quality of life test in the education and control groups were compared.

Eligibility criteria: Inclusion Criteria:

* Being between 8 and 18 years old
* Having been diagnosed with cancer and having completed treatment
* Having passed at least 30 and at most 120 days after completion of treatment.

Exclusion Criteria:

* Having chronic lung disease,
* Having a history of hospitalization due to infection in the last month,
* Having a history of surgical intervention due to cancer,
* Having insufficient cognitive and cognitive functions,
* Having an orthopedic problem affecting mobility or a history of musculoskeletal surgical intervention,
* Having cancer relapse during the 8-week training program,
* Having received additional chemotherapy for any reason despite having completed treatment,

Primary outcomes:
measure: Measurement of Pulmonary Function
timeFrame: 8 weeks
measure: Measurement of Respiratory Muscle Strength
timeFrame: 8 weeks
measure: Measurement of Functional Capacity
timeFrame: 8 weeks
measure: Measurement of Quality of Life
timeFrame: 8 weeks
measure: Measurement of Fatigue
timeFrame: 8 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakıf University
Study officials:
affiliation: Bezmialem Vakif University
name: Semiramis Özyılmaz, Assoc. Prof.
role: STUDY_DIRECTOR
References: