Clinical trial NCT02961413: A Prospective Cohort Study on Drug-induced Liver Injury in China（DILI-P）
Official title: A Multi-center, Prospective, Non-interventional Cohort Study on Drug Induced Liver Injury in Mainland China
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Drug-induced Liver Injury
Lead sponsor: Drug Induced Liver Disease Study Group
Sponsor class: OTHER
First posted: 2016-11-11
Enrollment: 10000
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: all patients with drug-induced liver injury

Brief summary: This is a multi-center, prospective, non-interventional cohort study .

Its primary objectives are:

1. assess DILI patients' clinical characteristics, disease progression and influencing factors in clinical practice;
2. learn about suspected drug caused DILI,rechallenging, liver biochemical abnormalities mode, etc.

Detailed description: The main purpose of this study is to understand patients with DILI clinical outcome and influencing factors in China's second and tertiary general hospitals (including Western medicine hospital, Chinese medicine hospital andIntegrated traditional Chinese and Western Medicine Hospital) and vulnerabilities of drug-induced liver injury specialist hospital (tuberculosis hospital, Pulmonary, etc.) in mainland.

The main purpose

1. assess the DILI patients' clinical outcomes and influencing factors in the real world;
2. learn about suspected drug caused DILI,rechallenging, liver biochemical abnormalities mode, etc.

Secondary objectives

1. assess the compliance of the DILI practice to the 2015 vision of the DILI guidelines in china.;
2. evaluate the histological features of DILI patients;
3. assessment DILI characteristics, prognosis and influencing factors in specific populations(such as the elderly, children with underlying liver disease background, etc.)

Eligibility criteria: Inclusion Criteria:

* Diagnosis of DILI patients with various types and severity according to the 2015 version of the Chinese DILI treatment guidelines
* RUCAM ≥6, or RUCAM between 3-5 is required by the three experts determined that the drug-induced liver injury
* patient can provide informed consent form

Exclusion Criteria:

* non-drug-induced liver injury

Primary outcomes:
measure: Disease progression of DILI (drug-induced liver injury ), i.e. death, liver failure, chronic DILI, recover
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Shanghai
country: China
facility: Renji hospital
Study officials:
affiliation: RenJi Hospital
name: Yimin Mao
role: STUDY_CHAIR
affiliation: No.85 Hospital of PLA
name: Chengwei Chen
role: STUDY_CHAIR
affiliation: Pulmonary Hospital of Lanzhou
name: Xingfang Li
role: PRINCIPAL_INVESTIGATOR
affiliation: First Hospital of China Medical University
name: Yiling Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Fuzhou General Hospital
name: Dongliang Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Changzhou Third People 's Hospital
name: Suocai Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: First Hospital of Shijiazhuang City
name: Rongxia Sang
role: PRINCIPAL_INVESTIGATOR
affiliation: Hebei Chest Hospital
name: Zhihui Li
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital of Heilongjiang Chinese Medicine University
name: Feng Sun
role: PRINCIPAL_INVESTIGATOR
affiliation: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
name: Wushu Yan
role: PRINCIPAL_INVESTIGATOR
affiliation: Bazhou People 's Hospital
name: Yanqin Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Mudanjiang Red Flag Hospital
name: Xu Lian
role: PRINCIPAL_INVESTIGATOR
affiliation: Pingdingshan People's Hospital No.1
name: Mingfang Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: General Hospital of Pingdingshan Coal Industry Company
name: Yanrong Shi
role: PRINCIPAL_INVESTIGATOR
affiliation: Luoyang Central Hospital
name: Hongwei Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Third Hospital Affiliated to Henan University of Science and Technology
name: Ximei Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of Luoyang
name: Hongling Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second Hospital Affiliated to Henan University of Science and Technology
name: Renping Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Beijing 302 Hospital
name: Zhengsheng Zou
role: PRINCIPAL_INVESTIGATOR
affiliation: Ruian People's Hospital
name: Jiguang Ding
role: PRINCIPAL_INVESTIGATOR
affiliation: Daqing oilfield general hospital
name: Yanjun Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: The No.123 Hospital of Chinese People's Liberation Army
name: Weixin He
role: PRINCIPAL_INVESTIGATOR
affiliation: Tianjin First Central Hospital
name: Wufang Qi
role: PRINCIPAL_INVESTIGATOR
affiliation: The No.211 Hospital of Chinese People's Liberation Army
name: Yuqin Xu
role: PRINCIPAL_INVESTIGATOR
affiliation: Beijin Youan Hospital,Capital Medical University
name: Jing Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Jiangxi Chest Hospital
name: Peilan Zong
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of Hangzhou Xiaoshan District
name: Yuefei Shen
role: PRINCIPAL_INVESTIGATOR
affiliation: Infectious Diseases Hospital of Shangqiu
name: Chunyan Zhou
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second People's Hospital of Wuhu
name: Baijing Ding
role: PRINCIPAL_INVESTIGATOR
affiliation: Wuhu Third People's Hospital
name: Liyun Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Affiliated Hospital of Hebei University of Engineering
name: Yongze Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: Fifth Hospital of Shijiazhuang City
name: Haibin Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
name: Hui Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: Beijing 302 Hospital
name: Hongling Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Henan University of Science and Technology
name: Yingjian Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Southwest Hospital, China
name: Qing Mao
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Shanxi Medical University
name: Liaoyun Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: First People's Hospital of Yunnan Province
name: Jiawei Gen
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Medical College,Shihezi University
name: Weize Zuo
role: PRINCIPAL_INVESTIGATOR
affiliation: Nanjing Chest Hospital
name: Xia Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Nanchang University
name: Xuan Zhu
role: PRINCIPAL_INVESTIGATOR
affiliation: Linyi People's Hospital
name: Feng Shuai
role: PRINCIPAL_INVESTIGATOR
affiliation: Hunan Chest Hospital
name: Kunyun Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Fifth People,Hospital of Suzhou
name: Chuanwu Zhu
role: PRINCIPAL_INVESTIGATOR
affiliation: Renmin Hospital of Wuhan University
name: Wei Ge
role: PRINCIPAL_INVESTIGATOR
affiliation: 85 Hospital of People's Liberation Army
name: Xiaojin Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Xiamen University
name: Jiajun Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: Xiangya Hospital of Central South University
name: Yan Huang
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital of Xinjiang Medical University
name: Fangping He
role: PRINCIPAL_INVESTIGATOR
affiliation: Xijing Hospital
name: Xinmin Zhou
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Inner Mongolia University of Science and Technology
name: Aiqing Lin
role: PRINCIPAL_INVESTIGATOR
affiliation: Wuhan General Hospital of Guangzhou Military
name: Xiaojing Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: Ruijin Hospital
name: Qing Xie
role: PRINCIPAL_INVESTIGATOR
affiliation: Xingtai People's Hospital
name: Qingge Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Peking University First Hospital
name: Yanyan Yu
role: PRINCIPAL_INVESTIGATOR
affiliation: Shenzhen Third People's Hospital
name: Jing Yuan
role: PRINCIPAL_INVESTIGATOR
affiliation: Kunming General Hospital of Chengdu Military Area Command
name: Shiwu Ma
role: PRINCIPAL_INVESTIGATOR
affiliation: Central South University
name: Jun Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhejiang Cancer Hospital
name: Qinghua Yao
role: PRINCIPAL_INVESTIGATOR
affiliation: The No.457 Hospital of Chinese People's Liberation Army
name: Yihong Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Second Hospital of Shanxi Medical University
name: Qi Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Xinjiang Autonomous Region Hospital of TCM
name: Xiaozhong Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Daqing Longnan Hopital
name: Yongwen Ma
role: PRINCIPAL_INVESTIGATOR
affiliation: Sir Run Run Shaw Hospital
name: Fangfang Lv
role: PRINCIPAL_INVESTIGATOR
affiliation: Ankang City Central Hospital
name: Xiaojun Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Fouth People's Hospital of Datong
name: Riwang Hu
role: PRINCIPAL_INVESTIGATOR
affiliation: Chongqing Traditional Chinese Medicine Hospital
name: Yi Song
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second Affiliated Hospital of Chongqing Medical University
name: Peng Hu
role: PRINCIPAL_INVESTIGATOR
affiliation: Beijing Ditan Hospital
name: Wen Xie
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital of Harbin Medical University
name: Yongguo Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Yanbian University Hospital
name: Haiyan Jin
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of Qinzhou
name: Zheng Li
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital Xi'an Jiaotong University
name: Shuixiang He
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Provincial Hospital
name: Lei Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Jilin University
name: Junqi Niu
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second People's Hospital of Liaoyuan
name: Bin Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital of Kunming Medical University
name: Jing You
role: PRINCIPAL_INVESTIGATOR
affiliation: WUHAN NO.7 HOSPITAL
name: Youqin Yan
role: PRINCIPAL_INVESTIGATOR
affiliation: General Hospital of The Yangtze River Shipping
name: Lvye Xv
role: PRINCIPAL_INVESTIGATOR
affiliation: Wuhan Mental Health Centre
name: Changyong Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Ya'nan University Affiliated Hospital
name: Guanghua Xv
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Anhui Medical University
name: Hongbin Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second Hospital of Nanjing Medical University
name: Yongfeng Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: Yuncheng Central Hospital
name: Xilian Dong
role: PRINCIPAL_INVESTIGATOR
affiliation: LinFen People's Hospital
name: Xuefeng Su
role: PRINCIPAL_INVESTIGATOR
affiliation: Shanxi Provincial Cancer Hospital
name: Mudan Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Affiliated Hospital of Inner Mongolia Medical University
name: Zhen Ma
role: PRINCIPAL_INVESTIGATOR
affiliation: West China Hospital
name: Hong Tang
role: PRINCIPAL_INVESTIGATOR
affiliation: Shanghai Shuguang Hospital
name: Chenghai Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: South China University of Science And Technology Affiliated Hospital
name: Zhenyu Yan
role: PRINCIPAL_INVESTIGATOR
affiliation: Jiangsu province hospital of TCM
name: Fei Qiao
role: PRINCIPAL_INVESTIGATOR
affiliation: Sichuan Province Hospital
name: Xingxiang Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: Nanfang Hospital, Southern Medical University
name: Jinjun Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Guangdong Provincial People's Hospital
name: Weihong Sha
role: PRINCIPAL_INVESTIGATOR
affiliation: First People's Hospital of Hangzhou
name: Jie Jin
role: PRINCIPAL_INVESTIGATOR
affiliation: Hainan General Hospital
name: Feng Lin
role: PRINCIPAL_INVESTIGATOR
affiliation: Cangzhou Central Hospital
name: Guoqi Zheng
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhong Shan Hospital
name: Jiyao Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: LanZhou University
name: Lin Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Tongji Medical College of Huazhong University of Science and Technology
name: Dongliang Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Center Hospital Of Maanshan
name: Li Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second Hospital of Anhui Medical University
name: Guizhou Zou
role: PRINCIPAL_INVESTIGATOR
affiliation: Fuyang First People's Hospital
name: Yong Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Yiwu Central Hospital
name: Lianqing Lou
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital of Hangzhou
name: Huaming Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Huzhou Central Hospital
name: Shifang Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Affiliated Hospital of Jiaxing University
name: Zhifen Pan
role: PRINCIPAL_INVESTIGATOR
affiliation: Hangzhou Hospital of Traditional Chinese Medicine
name: Wenlong Zheng
role: PRINCIPAL_INVESTIGATOR
affiliation: Hangzhou Xiaoshan Hospital of Traditional Chinese Medicine
name: Jingbo Pei
role: PRINCIPAL_INVESTIGATOR
affiliation: Hangzhou Xiaoshan First People's Hospital
name: Feng Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: Dongyang People's Hospital
name: Feng Qian
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhejiang Quhua Hospital
name: Jianzheng Mao
role: PRINCIPAL_INVESTIGATOR
affiliation: Shaoxing People's Hospital
name: Ahuo Ma
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital of Quzhou
name: Qinhong Zheng
role: PRINCIPAL_INVESTIGATOR
affiliation: Tongxiang First People's Hospital
name: Jufen Xu
role: PRINCIPAL_INVESTIGATOR
affiliation: Ningbo Yinzhou No.2 Hospital
name: Jiemin Hong
role: PRINCIPAL_INVESTIGATOR
affiliation: Ningbo Medical Center Lihuili Eastern Hospital
name: Jianwei Shen
role: PRINCIPAL_INVESTIGATOR
affiliation: Ningbo No.2 Hospital
name: Yunsong Qian
role: PRINCIPAL_INVESTIGATOR
affiliation: Jinhua Central Hospital
name: Weihong Du
role: PRINCIPAL_INVESTIGATOR
affiliation: Huzhou Hospital of Traditional Chinese Medicine
name: Jiaxin Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhejiang Construction Hospital
name: Qingjing Ru
role: PRINCIPAL_INVESTIGATOR
affiliation: The No.98 Hospital of Chinese People's Liberation Army
name: Chunsheng Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Baoding First Central Hospital
name: Yinxia Hao
role: PRINCIPAL_INVESTIGATOR
affiliation: Xi'an No.3 Hospital
name: Li Sun
role: PRINCIPAL_INVESTIGATOR
affiliation: Le Qin People's Hospital
name: Wenlei Hu
role: PRINCIPAL_INVESTIGATOR
affiliation: Second Affiliated Hospital of Xi'an Jiaotong University
name: Shuangsuo Dang
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhengzhou No.6 People's Hospital
name: Yu Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital of Heilongjiang Chinese Medicine University
name: Zhaoxia Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: Heilongjiang Provincial Hospital of Traditional Chinese Medicine
name: Yang Pan
role: PRINCIPAL_INVESTIGATOR
affiliation: Dandong City Infectious Disease Hospital
name: Yi Shen
role: PRINCIPAL_INVESTIGATOR
affiliation: Baoding City Infectious Disease Hospital
name: Xia Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Anshan Central Hospita
name: Qian Zhong
role: PRINCIPAL_INVESTIGATOR
affiliation: Xiangtan Central Hospita
name: Zhixiong Fang
role: PRINCIPAL_INVESTIGATOR
affiliation: Xiangxi Autonomous Prefecture People's Hospital
name: Xiaoping Xu
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of YueYang
name: Sihai Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The People's Hospital of Xuancheng City
name: Hui Tian
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of Lanzhou City
name: Shiquan Ka
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Province Chest Hospital
name: Dongfang Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Guangzhou First People's Hospital
name: Yuqiang Nie
role: PRINCIPAL_INVESTIGATOR
affiliation: Heilongjiang Mudanjiang Nanshan Hospital
name: Yan Song
role: PRINCIPAL_INVESTIGATOR
affiliation: Second Affiliated Hospital of Xi'an Jiaotong University
name: Xiaoyan Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: Hebei Medical University Third Hospital
name: Caiyan Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Hebei Medical University Third Hospital
name: Yuemin Nan
role: PRINCIPAL_INVESTIGATOR
affiliation: People 's Hospital of Kaizhou District, Chongqing City
name: Dingguo Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Public Health Clinical Center of Chengdu
name: Li Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: First Hospital of Hebei Medical University
name: Lixin Tong
role: PRINCIPAL_INVESTIGATOR
affiliation: West China Hospital,Huaxi University
name: Hao Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Jinshan Hospital Fudan University
name: Shurui Piao
role: PRINCIPAL_INVESTIGATOR
affiliation: Meng Chao Liver and Gallbladder Hospital of Fujian Medical University
name: Lvfeng Yao
role: PRINCIPAL_INVESTIGATOR
affiliation: Affiliated Hospital of Hebei University
name: Yanqing Tian
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Guangxi University of Chinese Medicine
name: Zhenbin Hu
role: PRINCIPAL_INVESTIGATOR
affiliation: No.2 Hospital Of Huhhot
name: Caisheng Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third Xiangya Hospital of Central South University
name: Xiaoyan Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Shandong Provincial Chest Hospital
name: Feng Jin
role: PRINCIPAL_INVESTIGATOR
affiliation: Donggang Center Hospital
name: Yanbo Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: The 3Th People's Hospital Of Hengshui
name: Zhiqiang Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Shandong Provincial Chest Hospital
name: Yu Xiong
role: PRINCIPAL_INVESTIGATOR
affiliation: Shandong Provincial Chest Hospital
name: Xinmei Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Nongan county
name: Yan Zhuang
role: PRINCIPAL_INVESTIGATOR
affiliation: Shandong Provincial Chest Hospital
name: Chaoren Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Tuberculosis Department, Shandong Provincialchest Hospital
name: Zhonghua Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Tuberculosis Department, Shandong Provincialchest Hospital
name: Meiying Lin
role: PRINCIPAL_INVESTIGATOR
affiliation: Affiliated Hospital of Hebei University
name: Jihong Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Center Hospital Of Maanshan
name: Jingyi Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Jinxian county
name: Sangen Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: The Fourth Affiliated Hospital of Nanchang University
name: Yongping Pan
role: PRINCIPAL_INVESTIGATOR
affiliation: Second Central Hospital of Baoding
name: Ruipu Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Lushan Tuberculosis Prevention and Control Hospital
name: Xueshan Tao
role: PRINCIPAL_INVESTIGATOR
affiliation: Ganzhou People's Hospital
name: Shilin Qu
role: PRINCIPAL_INVESTIGATOR
affiliation: Jingzhou Chest Hospital
name: Jie Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Luxi county
name: Diefeng Yin
role: PRINCIPAL_INVESTIGATOR
affiliation: Chinese Medicine Hospital of Gao'an City
name: Jianfeng Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Sinopharm Dongfeng General Hospital
name: Xueqiang Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: Fujian Cancer Hospital
name: Jianwei Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: The 94th Hospital of the People's Liberation Army
name: Yong Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Nanchang county
name: Chengyun Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Xunyang
name: Shengjun Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Weifang
name: Jizhu Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Weifang
name: Jianjun Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Jiujiang City
name: Gang Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Fengyang County People's Hospital
name: Yong Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Infectious Disease Hospital Of Heilongjiang Province
name: Yansheng Sun
role: PRINCIPAL_INVESTIGATOR
affiliation: Third People's Hospital Of Jiujiang City
name: Xiong Tang
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Bengbu Medical University
name: Shousong Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Lingbi County People's Hospital
name: Jiandao Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Liu'an People's Hospital
name: Long Yu
role: PRINCIPAL_INVESTIGATOR
affiliation: Shexian People's Hospital
name: Weihua Xun
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Provincial Hospital
name: Yong Jia
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Provincial Hospital Infectious Hospital
name: Yi Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second People's Hospital Of Lanzhou City
name: Zhengmao Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhuzhou No.2 Hospital
name: Jianmin Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Anhui Medical University
name: Huafa Yin
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Province Xuancheng City Central Hospital
name: Meilong Ding
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Dongzhi county
name: Shanlou Hu
role: PRINCIPAL_INVESTIGATOR
affiliation: Xiaoxian People's Hospital
name: Yi Ding
role: PRINCIPAL_INVESTIGATOR
affiliation: Huangshan City People's Hospital
name: Weidong Fang
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Wuhu County Hospital
name: Liu Hong
role: PRINCIPAL_INVESTIGATOR
affiliation: Bozhou Hospital of Traditional Chinese Medicine
name: Xiaorong Xu
role: PRINCIPAL_INVESTIGATOR
affiliation: Suzhou Hospital Affiliated To Anhui Medical University
name: Delian Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second People's Hospital Of Hefei
name: Yong Huang
role: PRINCIPAL_INVESTIGATOR
affiliation: Dazhou Central Hospital
name: Qiliang Tan
role: PRINCIPAL_INVESTIGATOR
affiliation: Huainanchaoyang Hospital
name: Songqing Liao
role: PRINCIPAL_INVESTIGATOR
affiliation: The People's Hospital Huaibei
name: Bin Yao
role: PRINCIPAL_INVESTIGATOR
affiliation: Huainan First People's Hospital
name: Shuiqing Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: Infectious Disease Hospital Of Baishan
name: Yanmin Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Chest Hospital
name: Lei Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Chest Hospital
name: Wenhong Lin
role: PRINCIPAL_INVESTIGATOR
affiliation: Tonghua Central Hospital
name: Wengang Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Ninth People's Hospital Of Jilin
name: Chongfeng Gu
role: PRINCIPAL_INVESTIGATOR
affiliation: Jilin Tuberculosis Prevention and Control Institute
name: Zhe Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Jixijikuang Hospital
name: Junfeng Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Tianjin Tuberculosis Prevention and Control Center
name: Jie Zhou
role: PRINCIPAL_INVESTIGATOR
affiliation: Renmin Hospital Of Shayang
name: Guomin Tang
role: PRINCIPAL_INVESTIGATOR
affiliation: Baiyupao Hospital
name: Zhuo Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Weifang
name: Guohui Zhu
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Weifang
name: Xingping Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhangshu People's Hospital
name: Jingen Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Beijing Friendship Hospital
name: Xinyan Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Avic 363 Hospital
name: Hongliang Liang
role: PRINCIPAL_INVESTIGATOR
affiliation: Yiyang Central Hospital
name: Lijun Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: Fengcheng People's Hospital
name: Fangchun Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Xiangdong Hospital Hunan Normal University
name: Jianwei Zhou
role: PRINCIPAL_INVESTIGATOR
affiliation: Zhangjiajie City People's Hospital
name: Zhongrui Su
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third Xiangya Hospital of Central South University
name: Wei Xiao
role: PRINCIPAL_INVESTIGATOR
affiliation: Qitaihe Coal Mine Hospital
name: Bohui Yuan
role: PRINCIPAL_INVESTIGATOR
affiliation: Beilun People's Hospital
name: Chun Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: Luohe Psychiatric Hospital
name: Gaizhi Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: No.2 People's Hospital of Fuyang City
name: Ming Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Qiqihar Tuberculosis Prevention and Control Center
name: Zhixue Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of Yunnan
name: Wei Yue
role: PRINCIPAL_INVESTIGATOR
affiliation: Ningbo Medical Center Lihuili Eastern Hospital
name: Li Zhou
role: PRINCIPAL_INVESTIGATOR
affiliation: Anqing Municipal Hospitalis
name: Xiaoqing Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Dengzhou Central Hospital
name: Chunge Tian
role: PRINCIPAL_INVESTIGATOR
affiliation: No.1 People's Hospital Of Zhumadian
name: Tianming Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital of Zhengzhou University
name: Ji'ao Han
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Xinye
name: Jingxia Ma
role: PRINCIPAL_INVESTIGATOR
affiliation: The First People's Hospital of Xinmi
name: Jie Bao
role: PRINCIPAL_INVESTIGATOR
affiliation: Weihui People's Hospital
name: Jianhui Sun
role: PRINCIPAL_INVESTIGATOR
affiliation: Yuanyang Central Hospital
name: Xiaoju Luo
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Hebi
name: Weili Niu
role: PRINCIPAL_INVESTIGATOR
affiliation: Hepatobiliary Hospital Of Jilin
name: Ming Wang
role: PRINCIPAL_INVESTIGATOR
affiliation: Dengzhou Hospital of TCM
name: Yiwen Qiao
role: PRINCIPAL_INVESTIGATOR
affiliation: Suining Infectious Diseases Hospital
name: Chuan Zhao
role: PRINCIPAL_INVESTIGATOR
affiliation: Anhui Mental Health Center
name: Xiaoqian Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Wugang People's Hospital
name: Jingchao Guo
role: PRINCIPAL_INVESTIGATOR
affiliation: General Hospital of Heilongjiang Provincial Agricultural Reclamation Bureau
name: Weihua Liu
role: PRINCIPAL_INVESTIGATOR
affiliation: Baoji People's Hospital
name: Feng Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Taian Enliang Hospital
name: Man Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Xiuyan Central Hospital
name: Hong Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Anshan Mental Health Center
name: Shansong Bai
role: PRINCIPAL_INVESTIGATOR
affiliation: General Hospital Of Liaohe Oilfield
name: Xiuying Men
role: PRINCIPAL_INVESTIGATOR
affiliation: Tiefa Coal Group General Hospital
name: Yanhua Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: The People's Hospital Of Lingchengqu
name: Junzu Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: Baoshan Hospital Of Chifeng
name: Haiyan Zhou
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third Affiliated Hospital of Jinzhou Medical University
name: Yu Feng
role: PRINCIPAL_INVESTIGATOR
affiliation: Liaoyang City Central Hospital
name: Yihua Song
role: PRINCIPAL_INVESTIGATOR
affiliation: Panshan Mental Rehabilitation Hospital
name: Tao Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: Wafangdian Central hospital
name: Yueping Li
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Ningjinxian
name: Guosheng Jiang
role: PRINCIPAL_INVESTIGATOR
affiliation: Taian City Central Hospital
name: Bo Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Hebei Chest Hospital
name: Shujun Geng
role: PRINCIPAL_INVESTIGATOR
affiliation: The Second People's Hospital Of Changzhou
name: Jin Huang
role: PRINCIPAL_INVESTIGATOR
affiliation: The 169th Hospital Of P.L.A.
name: Fengming Yin
role: PRINCIPAL_INVESTIGATOR
affiliation: Public Health Affiliated Hospital,University Of South China
name: Weiguo He
role: PRINCIPAL_INVESTIGATOR
affiliation: Affiliated Nanhua Hospital，University Of South China
name: Zhefeng Zhong
role: PRINCIPAL_INVESTIGATOR
affiliation: First Affiliated Hospital Xi'an Jiaotong University
name: Yuan Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Third People's Hospital Of Changzhou
name: Guoping Fang
role: PRINCIPAL_INVESTIGATOR
affiliation: Tonghua Tuberculosis Prevention and Control Center
name: Qiang Miao
role: PRINCIPAL_INVESTIGATOR
affiliation: The Fourth People's Hospital of Chenzhou
name: Xin'guang Huang
role: PRINCIPAL_INVESTIGATOR
affiliation: The Fourth People's Hospital Of Zibo
name: Duanbao Tian
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Shishou
name: Yaoming Yuan
role: PRINCIPAL_INVESTIGATOR
affiliation: Yanji Tuberculosis Prevention and Control Center
name: Yuzi Lin
role: PRINCIPAL_INVESTIGATOR
affiliation: Dunhua Tuberculosis Prevention and Control Center
name: Ligang Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Huichun Tuberculosis Prevention and Control Center
name: Yu Zhang
role: PRINCIPAL_INVESTIGATOR
affiliation: Yanji Brain Hospital
name: Chunrong Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Yanji Brain Hospital
name: Aimin Wu
role: PRINCIPAL_INVESTIGATOR
affiliation: Antu Tuberculosis Prevention and Control Center
name: Xiangzhu Bai
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Zhongxiang
name: Shaorong Deng
role: PRINCIPAL_INVESTIGATOR
affiliation: Tianjin Xiqing Hospital
name: Shaoguang Yang
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Zhenjiang
name: Guohong Ge
role: PRINCIPAL_INVESTIGATOR
affiliation: The Affiliated Hospital of Xuzhou Medical University
name: Xuebing Yan
role: PRINCIPAL_INVESTIGATOR
affiliation: People's Hospital Of Songzi
name: Sheng Huang
role: PRINCIPAL_INVESTIGATOR
affiliation: Affiliated Hospital of Hangzhou Normal University
name: Gongying Chen
role: PRINCIPAL_INVESTIGATOR
affiliation: Tianjin Second People's Hospital
name: Ping Li
role: PRINCIPAL_INVESTIGATOR
affiliation: The First Affiliated Hospital of Anhui Medical University
name: Jiehua Li
role: PRINCIPAL_INVESTIGATOR
affiliation: Beijing YouAn Hospital
name: Weiwei Kang
role: PRINCIPAL_INVESTIGATOR
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