Clinical trial NCT03269253: Maternal Loss of Control Eating
Official title: Maternal Loss of Control Eating: a Longitudinal Study of Maternal and Child Outcomes
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Eating Disorder
Obesity
Keywords: ALSPAC
longitudinal
Lead sponsor: Icahn School of Medicine at Mount Sinai
Sponsor class: OTHER
First posted: 2017-08-31
Enrollment: 14451
Sex: FEMALE
Minimum age (years): 16
Maximum age (years): 43
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All pregnant women living in the geographical area of Avon, UK, who were expected to deliver their baby between 1st April 1991 and 31st December 1992, were recruited. 14,541 women were enrolled. Amongst these pregnancies, there were a total of 14,676 fetuses, resulting in 14,062 live births and 13,798 children who were alive at 1 year of age and were singletons.

Brief summary: This study focused on investigating the effects of maternal disordered eating on maternal and child outcomes as part of a secondary data analysis of the Avon Longitudinal Study of Parents and Children (ALSPAC).

Detailed description: Deidentified and anonymised data already collected as part of the ALSPAC study will be analysed to investigate the effects of maternal eating on maternal and child outcomes (diet, eating, weight, metabolic). The Avon Longitudinal Study of Parents and Children (ALSPAC) is a longitudinal, prospective study designed to examine the effects of environment, genetics and other factors on health and development.All pregnant women living in the geographical area of Avon, UK, who were expected to deliver their baby between 1st April 1991 and 31st December 1992, were recruited. 14,541 women were enrolled. Amongst these pregnancies, there were a total of 14,676 fetuses, resulting in 14,062 live births and 13,798 children who were alive at 1 year of age and were singletons. The ALSPAC study website contains details of all the data that is available through a fully searchable data Dictionary (http://www.bris.ac.uk/alspac/researchers/data-access/data-dictionary/).

Missingness will be assessed and standard data analytical techniques such as MI will be used.Crude and adjusted logistic, linear, and multinomial regression models will be employed.

Eligibility criteria: Inclusion Criteria:

-

Exclusion Criteria:

* multiple pregnancies
* no questionnaire data at 32 weeks.

eligibility criteria : enrolled in the ALSPAC study; inclusion: all women part of the ALSPAC study;

Primary outcomes:
measure: birth weight
timeFrame: Day 1
Secondary outcomes:
measure: BMI
timeFrame: average 21 years
measure: Food Frequency Questionnaire (FFQ)
timeFrame: average 9 months
measure: Food Frequency Questionnaire
timeFrame: average 21 years
Other outcomes:
Locations:
city: New York
country: United States
facility: Icahn School of Medicine at Mount Sinai
state: New York
Study officials:
affiliation: Icahn School of Medicine at Mount Sinai
name: Nadia Micali, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Micali N, Al Essimii H, Field AE, Treasure J. Pregnancy loss of control over eating: a longitudinal study of maternal and child outcomes. Am J Clin Nutr. 2018 Jul 1;108(1):101-107. doi: 10.1093/ajcn/nqy040.