Clinical trial NCT05335837: Ilioinguinal/Iliohypogastric Block for Inguinal Hernia Repair
Official title: Postoperative Recovery Time in Inguinal Hernia Repair Under Ilioinguinal, Iliohypogastric Nerve Block and Sedation Versus General Anesthesia: a Propensity Score Matched-cohort Retrospective Study
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Anesthesia
Lead sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sponsor class: OTHER
First posted: 2022-04-19
Enrollment: 350
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient

Brief summary: Inguinal hernia have traditionally been done under general anesthesia. While safe, general anesthesia is associated with potential postoperative nausea/vomiting and drowsiness. Additionally, the recent COVID19 pandemic has heightened the precaution to avoid aerosol generating procedures (AGP) if possible. General anesthesia requires airway manipulation, thus necessitate performing an AGP. Recently, we began using peripheral nerve block and sedation as primary anesthetic technique for inguinal hernia repairs. While surgeon administered local anesthetic, also known as local infiltration, has been done for inguinal hernia repair, using specific nerve blocks and sedation has not been compared with general anesthesia. We believe the advantage of this novel technique can improve postoperative recovery. This retrospective study will compare the total hospital length of stay of those receiving nerve blocks and sedation as primary anesthetic techniques versus those with general anesthesia.


Eligibility criteria: Inclusion Criteria:

* 18 years or older
* American Society of Anesthesiologists (ASA) Physical Status I to III
* Body Mass Index (BMI) less than 45
* Single hernia repair, elective, ambulatory surgery

Exclusion Criteria:

* Opioid dependence (30 mg oral morphine equivalents daily or more)
* History of malignant hyperthermia
* Pregnancy

Primary outcomes:
measure: Postoperative recovery time
timeFrame: Time from exiting operating room to time ready for hospital discharge, up to 100 hours
Secondary outcomes:
measure: Preoperative time
timeFrame: Time from patient registration to entering operating room, up to 100 hours
measure: Intraoperative time
timeFrame: Time from entering to exiting operating room, up to 100 hours
measure: Hospital length of stay
timeFrame: Time from patient registration to ready for hospital discharge, up to 100 hours
measure: Postoperative nausea vomiting
timeFrame: Time from exiting operating room to time ready for hospital discharge, up to 100 hours
measure: Severe pain
timeFrame: Time from exiting operating room to time ready for hospital discharge, up to 100 hours
measure: Desaturation
timeFrame: Time from exiting operating room to time ready for hospital discharge, up to 100 hours
measure: Postoperative opioid dose
timeFrame: Time from exiting operating room to time ready for hospital discharge, up to 100 hours
Other outcomes:
Locations:
city: London
country: Canada
facility: Cheng Lin
state: Ontario
Study officials:
References: