Clinical trial NCT05669118: Dental Autotransplantation or Immediate Single Implant for the Replacement of a Hopeless Molar.
Official title: Dental Autotransplantation or Immediate Single Implant for the Replacement of a Hopeless Molar: a Comparative Case Series Study.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Transplantation, Autologous
Autografts
Surgery, Oral
Lead sponsor: Aula Dental Avanzada
Sponsor class: OTHER
First posted: 2022-12-30
Enrollment: 29
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who come to the clinic and need a tooth extracted.

Brief summary: The aim of this comparative study is to know the differences between the soft tissue volume changes around the autotransplanted tooth and the dental implant placed immediately after the extraction of a posterior tooth. Patient-centered results will also be obtained after having received one or the other treatment.

Detailed description: Dental autotransplantation has high levels of success in permanent teeth with open apex. The results of success in permanent teeth with closed apex are somewhat lower but sufficient to consider the treatment as a viable alternative and to extend the therapeutic range of the treatment to older ages.

The aim of this prospective observational investigation is to evaluate the dimensional and attachment changes that occur in the treated areas and in the autotransplanted teeth respectively of adult patients with permanent teeth with closed apex. All adult patients receiving a dental autotransplantation between the years 2022 and 2023 will be included.

Pre-treatment, volume and insertion parameters will be recorded before and one year after treatment. The comparison with the extraction and dental implant treatment will be made using the digital records that are usually obtained during the performance of this treatment. The comparison will be made with the same number of patients who have been recruited for the dental autotransplant treatment, and the volumetric changes that occur will also be analyzed.

The volume comparisons will be carried out using the Medit Link digital measurement software (Medit, Seoul, Republic of Korea) and data will be obtained and analyzed statistically in order to draw the appropriate conclusions.

Eligibility criteria: Inclusion Criteria:

* Patients in ASA-I health status
* Aged between 18 and 80 years,
* Present a tooth in need of extraction with a mature candidate donor tooth compatible with the recipient bed
* Acceptance of proposed treatment of dental autotransplantation

Exclusion Criteria:

* Unavailability of a candidate donor tooth
* Refusal of proposed treatment of dental autotransplantation

Primary outcomes:
measure: Soft tissue volume changes
timeFrame: 2 times measurement: day 0 and 6 months after
measure: Periodontal probing pocket depth
timeFrame: 6 months after
Secondary outcomes:
measure: Patients satisfaction after treatment
timeFrame: 6 months after the reception of the treatment
Other outcomes:
Locations:
city: Alicante
country: Spain
facility: Clínica Dental Esteve
Study officials:
affiliation: Clínica Dental Esteve
name: Guillem Esteve-Pardo, PhD
role: PRINCIPAL_INVESTIGATOR
References: