Clinical trial NCT06017154: Acute Effect of Motor-Cognitive Training
Official title: The Acute Effects of Brain Activation and Functional Connectivity Following Motor-cognitive Training Using Functional MRI
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Injury;Sports
Keywords: injury prevention
cognition
physical performance
athletic training
Lead sponsor: University of Kentucky
Sponsor class: OTHER
First posted: 2023-08-30
Enrollment: 21
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes). The training program will comprise of integrate neuromuscular (agility, dynamic postural stability, shuffling, rapid acceleration/deceleration, plyometrics, lateral shuffle, and core stability) and cognitive (reaction time, processing speed, task switching, decision-making, and working memory) challenges.


Eligibility criteria: Inclusion Criteria:

* Physically active

Exclusion Criteria:

* Injury to the muscle or bone (upper extremity, lower extremity, or back) within the past 3 months
* Had musculoskeletal surgery or fracture (required open reduction internal fixation or within the last 12 months)
* Had a concussion or mild head injury within the last year
* Have been diagnosed with any kind of neurological, vestibular, or visual disturbance that impairs mobility
* Currently taking medications that affect the central nervous system
* Pregnant or suspicions of being pregnant
* Have metal fragments, pins, plates, or clips, shrapnel, body piercings that cannot be removed, have surgical implants or orthodontics that cannot be removed
* Have claustrophobia
* Have a history of cognitive impairment

Primary outcomes:
measure: Change in brain activation
timeFrame: 2 hours, pre-training session and immediately post-training session
measure: Change in functional connectivity
timeFrame: 2 hours, pre-training session and immediately post-training session
measure: Change in reaction time
timeFrame: 2 hours, pre-training session and immediately post-training session
measure: Change in accuracy
timeFrame: 2 hours, pre-training session and immediately post-training session
Secondary outcomes:
measure: Demographic/Injury History Form
timeFrame: Once, pre-training
measure: Defense Veterans Pain Rating Scale
timeFrame: Once, pre-training
measure: Modified Disablement In Physically Active Scale
timeFrame: Once, pre-training
measure: NASA Physical Activity Survey
timeFrame: Once, pre-training
measure: Heart rate
timeFrame: 35 minutes, during the training session
measure: Average reaction time during the intervention
timeFrame: 30 minutes, during the training session
measure: Misses during the training session
timeFrame: 30 minutes, during the training session
measure: Hits during the training session
timeFrame: 30 minutes, during the training session
measure: Number of errors during the training session
timeFrame: 30 minutes, during the training session
measure: Rate of perceived exertion
timeFrame: 30 minutes, during the training session
measure: Perceived cognitive difficulty
timeFrame: 30 minutes, during the training session
Other outcomes:
Locations:
city: Lexington
country: United States
facility: University of Kentucky
state: Kentucky
Study officials:
affiliation: University of Kentucky
name: Ke'La H Porter, MS
role: PRINCIPAL_INVESTIGATOR
References: