Clinical trial NCT05442099: The Effect of Iso-Principal Based Music Playlists on Anxiety
Official title: The Effect of Iso-Principal Based Music Playlists on Anxiety
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Anxiety State
Lead sponsor: Toronto Metropolitan University
Sponsor class: OTHER
First posted: 2022-07-01
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 38
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Chronic anxiety is a growing psychological challenge worldwide and at pre-clinical levels, can be disabling. Some research suggests music may reduce anxiety symptoms as effectively as anti-anxiety drugs without the adverse side effects. The iso principle suggests that the effectiveness of music interventions for mood management can be maximized by commencing a session with music that matches an individual's current emotional state and then gradually moving toward their desired emotional state. Our previous work demonstrated that a playlist generated by a music recommendation system that uses the iso-principal, along with music informatics, auditory beat stimulation, and reinforcement learning can reduce somatic and cognitive anxiety. However, it is unknown whether music playlists based on the iso-principal alone can reduce anxiety. In this study, the investigators wish to examine whether music playlists (\~30 min long) based on the iso-principal (neutral to calm) will reduce anxiety after anxiety induction compared to a calm music playlist. The investigators hypothesize that the iso-principal playlist will have greater state anxiety reduction compared to the calm playlist.

Detailed description: Chronic anxiety is a growing psychological challenge worldwide and at pre-clinical levels, can be disabling. Some research suggests music may reduce anxiety symptoms as effectively as anti-anxiety drugs without the adverse side effects. The iso principle suggests that the effectiveness of music interventions for mood management can be maximized by commencing a session with music that matches an individual's current emotional state and then gradually moving toward their desired emotional state. Our previous work demonstrated that a playlist generated by a music recommendation system that uses the iso-principal, along with music informatics, auditory beat stimulation, and reinforcement learning can reduce somatic and cognitive anxiety. However, it is unknown whether music playlists based on the iso-principal alone can reduce anxiety. In this study, the investigators wish to examine whether music playlists (\~30 min long) based on the iso-principal (neutral to calm) will reduce anxiety after anxiety induction compared to a calm music playlist. The investigators hypothesize that the iso-principal playlist will have greater state anxiety reduction compared to the reverse-iso and calm playlists. Participants (n = 100) will be recruited and randomly assigned to one of three groups 1) Iso principal playlist, 2) Calm playlist. Prior to their treatment, all participants will undergo anxiety induction (recall an anxiety-provoking event, while listening to anxiety-inducing music). State anxiety (STICSA), positive and negative affect (PANAS), arousal, and valence (SAM) will be measured pre-post anxiety induction and after treatment. This work will be the first of its kind to examine whether a playlist based on the iso-principal is effective at reducing anxiety.

Eligibility criteria: Inclusion Criteria:

* Participants who have no hearing impairments
* Participants who have no cardiac issues.
* Participants who have no history of seizures and epilepsy.

Exclusion Criteria:

* Participants who have hearing impairments
* Participants who have cardiac issues.
* Participants who have a history of seizures and epilepsy.

Primary outcomes:
measure: Anxiety: State Trait Inventory for Cognitive and Somatic Anxiety (STICSA)
timeFrame: 30 minutes
Secondary outcomes:
measure: Mood: Positive and Negative Affect Scale (PANAS)
timeFrame: 30 minutes
Other outcomes:
Locations:
Study officials:
affiliation: Toronto Metropolitan University
name: Frank Russo, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Toronto Metropolitan University
name: Adiel Mallik, PhD
role: STUDY_DIRECTOR
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