Clinical trial NCT01126918: Eating Disorders Prevention: An Effectiveness Trial for At-Risk College Students
Official title: Eating Disorders Prevention: An Effectiveness Trial for At-Risk College Students
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Eating Disorders
Obesity
Keywords: Eating Disorders
Obesity
Body Dissatisfaction
Female
Lead sponsor: Oregon Research Institute
Sponsor class: OTHER
Collaborators: name: University of Texas at Austin
name: Drexel University
First posted: 2010-05-20
Enrollment: 432
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This three-site effectiveness trial will test whether a brief dissonance-based eating disorder prevention program produces intervention effects when college counselors, psychologists, and nurses are responsible for participant recruitment, screening, and intervention delivery under ecologically valid conditions.

Detailed description: Threshold and subthreshold eating disorders affect over 10% of young women and are associated with functional impairment, distress, psychiatric comorbidity, medical complications, mortality, and risk for obesity onset. Accordingly, a pressing public healthy priority is to develop effective prevention programs for eating pathology. The proposed project will be the first effectiveness trial to test whether an eating disorder prevention program with strong empirical support from efficacy trials produces effects under ecologically valid conditions among high-risk female college students, which is a vital step toward widespread dissemination of programs developed with NIH funding. The proposed cost-effectiveness analyses and examination of process factors that predict larger intervention effects will also represent novel contributions to the literature.

Eligibility criteria: Inclusion Criteria:

* (1) is a registered student at a participating school, (2) self-reports body image concerns

Exclusion Criteria:

* meets DSM-IV criteria for anorexia nervosa, bulimia nervosa, or binge eating disorder

Primary outcomes:
measure: eating disorder symptoms, risk for future eating disorder and obesity onset
timeFrame: 2 years
Secondary outcomes:
measure: mediators to intervention effects
timeFrame: 2 years
measure: moderators to program effects
timeFrame: 2 years
Other outcomes:
Locations:
city: Eugene
country: United States
facility: Northwest Christian University
state: Oregon
city: Eugene
country: United States
facility: University of Oregon
state: Oregon
city: Philadelphia
country: United States
facility: Drexel University
state: Pennsylvania
city: Philadelphia
country: United States
facility: University of Pennsylvania
state: Pennsylvania
city: Philadelphia
country: United States
facility: Temple University
state: Pennsylvania
city: Austin
country: United States
facility: University of Texas at Austin
state: Texas
city: Georgetown
country: United States
facility: Southwestern University
state: Texas
Study officials:
affiliation: Oregon Research Institute
name: Eric Stice, Ph.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: Drexel University
name: Meghan Butryn, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Stice E, Desjardins CD, Rohde P. Young women who develop anorexia nervosa exhibit a persistently low premorbid body weight on average: A longitudinal investigation of an important etiologic clue. J Psychopathol Clin Sci. 2022 Jul;131(5):479-492. doi: 10.1037/abn0000762. Epub 2022 Jun 2.
citation: Stice E, Desjardins CD, Rohde P, Shaw H. Sequencing of symptom emergence in anorexia nervosa, bulimia nervosa, binge eating disorder, and purging disorder and relations of prodromal symptoms to future onset of these disorders. J Abnorm Psychol. 2021 May;130(4):377-387. doi: 10.1037/abn0000666.
citation: Stice E, Rohde P, Shaw H, Desjardins C. Weight suppression increases odds for future onset of anorexia nervosa, bulimia nervosa, and purging disorder, but not binge eating disorder. Am J Clin Nutr. 2020 Oct 1;112(4):941-947. doi: 10.1093/ajcn/nqaa146.