Clinical trial NCT05462977: Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Official title: Efficacy of Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Exercise
Gait
Cognitive Decline
Caregiver Burden
Cognitive Impairment
Dementia
Alzheimer Disease
Mild Cognitive Impairment
Respite Care
Mental Health
Depression
Music Therapy
Psychosocial Intervention
Cognition
Geriatric Assessment
Cognitive Dysfunction
Cognitive Aging
Outcome Assessment, Health Care
Balance
Fall
Walking
Affect
Physical Exertion
Memory Deficit
Memory Disorders
Memory Impairment
Neuropsychological Tests
Executive Function
Middle Aged
Healthy Aging
Elderly
Keywords: Physical Activity
Rhythmic Entrainment
Synchronous Music
Rhythmic Auditory Stimulation
Rhythmic Auditory Cue
Gait Training
Mobility
Movement
Perceived Exertion
Musical Pleasure
Groove
Memory
Executive Function
Older Adults
Lead sponsor: University of North Carolina, Greensboro
Sponsor class: OTHER
First posted: 2022-07-18
Enrollment: 18
Sex: ALL
Minimum age (years): 55
Maximum age (years): 99
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Participants will be invited to participate in a music-based group exercise program for 20 weeks (30 - 40 min/day, up to 6 days/week).
Primary purpose: TREATMENT

Brief summary: Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults. Up to forty participants will be recruited to participate in a music-based light-to-moderate intensity group exercise program for 20 weeks (30 - 40 min/day, up to 6 days/week), which is designed for older adults with or without functional limitations to exercise with chairs for the improvement of aerobic capacity, upper and lower body strength, and balance control at a gradually increasing pace. During the exercise sessions, participants will be trained to move in time with music playlists in synchronous tempos. Primary outcomes are cognitive performance, mobility, and health-related quality of life measured before and after the intervention. Secondary outcomes are adherence to the exercise program as a potential mediator of the treatment.

Detailed description: Researchers at the University of North Carolina at Greensboro are conducting a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults. Up to forty participants will be recruited to participate in a music-based light-to-moderate intensity group exercise program for 20 weeks (30 - 40 min/day, up to 6 days/week), which is designed for older adults with or without functional limitations to exercise with chairs for the improvement of aerobic capacity, upper and lower body strength, and balance control at a gradually increasing pace. During the exercise sessions, participants will be trained to move in time with music playlists in synchronous tempos. Primary outcomes are cognitive performance, mobility, and health-related quality of life measured before and after the intervention. Secondary outcomes are adherence to the exercise program as a potential mediator of the treatment. The research team aims to determine whether (1) a music-based light-to-moderate intensity group exercise intervention beneficially impacts mobility, cognitive function, and health-related quality of life in community-dwelling older adults; (2) the treatment effect is mediated by adherence to physical activity; and (3) the treatment effect is moderated by cognitive impairment or functional limitations.

Eligibility criteria: Inclusion Criteria:

* 55 - 99 years old
* Capable of being ambulatory with or without an assistive device.
* No cardiac or pulmonary conditions or any neurological or musculoskeletal comorbidity or pain that would make light-intensity exercise dangerous, determined by the Physical Activity Readiness Questionnaire for Everyone or confirmed by their local medical practitioner if necessary.
* Having adequate hearing for a conversation (including with hearing aids)
* Capable of following the study procedures
* No severe anxiety or depression
* Mild to moderate cognitive impairment

Exclusion Criteria:

* Age younger than 55 or older than 99
* Severe anxiety or depression
* Severe cognitive impairment

Primary outcomes:
measure: Change of fall risks
timeFrame: Baseline and change from baseline at month 5
measure: Change of walking endurance
timeFrame: Baseline and change from baseline at month 5
measure: Change of balance control
timeFrame: Baseline and change from baseline at month 5
measure: Change of lower body strength
timeFrame: Baseline and change from baseline at month 5
measure: Change of cognitive function
timeFrame: Baseline and change from baseline at month 5
measure: Change of health-related quality of life
timeFrame: Baseline and change from baseline at month 5
Secondary outcomes:
Other outcomes:
Locations:
city: Greensboro
country: United States
facility: UNC Greensboro
state: North Carolina
Study officials:
affiliation: University of North Carolina, Greensboro
name: Shin Park, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Park KS, Buseth L, Hong J, Etnier JL. Music-based multicomponent exercise training for community-dwelling older adults with mild-to-moderate cognitive decline: a feasibility study. Front Med (Lausanne). 2023 Aug 21;10:1224728. doi: 10.3389/fmed.2023.1224728. eCollection 2023.