Clinical trial NCT06566859: Comparison of ESP Block and M-TAPA Block Efficiency in Postoperative Analgesia Management in Nephrectomy Cases
Official title: Comparison of ESP Block and M-TAPA Block Efficiency in Postoperative Analgesia Management in Nephrectomy Cases
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Pain, Postoperative
Keywords: nerve block
pain management
postoperative period
postoperative complications
regional anesthesia
pain
Lead sponsor: Başakşehir Çam & Sakura City Hospital
Sponsor class: OTHER_GOV
First posted: 2024-08-22
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients aged 18 and over with ASA1-2 who underwent elective nephrectomy.

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Brief summary: Relieving postoperative nephrectomy pain requires multimodal approaches. Peripheral blocks such as ESP block and M-TAPA block and multimodal analgesics reduce side effects by reducing the use of other analgesics. This study aimed to compare the effectiveness of erector spinae plane block (ESP block) and modified thoracoabdominal nerve blocking with perichondrial approach (M-TAPA block) in postoperative analgesia management in nephrectomy cases.

Detailed description: Relieving postoperative nephrectomy pain requires multimodal approaches. The most commonly used in the treatment of pain are nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, and infiltration of local anesthetics. Due to the side effects of NSAIDs and opioids, the application of regional analgesia techniques can reduce complications while providing better analgesia quality. Peripheral blocks such as ESP block and M-TAPA block and multimodal analgesics reduce side effects by reducing the use of other analgesics. Pain is considered one of the most important factors affecting the quality of healing. Postoperative pain delays the postanesthesia care unit, hospital stay, early ambulation, increases resource utilization, and negatively affects patient satisfaction. If postoperative analgesia is provided, all these negativities will be eliminated. This study aimed to compare the effectiveness of erector spinae plane block (ESP block) and modified thoracoabdominal nerve blocking with perichondrial approach (M-TAPA block) in postoperative analgesia management in nephrectomy cases.

Eligibility criteria: Inclusion Criteria:

* All patients aged 18 and over with ASA1-2 who underwent elective nephrectomy

Exclusion Criteria:

* ASA ≥3
* Body mass index\>35 kg/ m²
* Infection in the block area
* Coagulation disorder,
* Known allergy to local anesthetics
* Pregnant
* Patient with neuropathy
* Patient without cooperation
* Patient who refuses to participate in the study
* Patients under 18 years of age

Primary outcomes:
measure: Postoperative Pain Management
timeFrame: 0.hour
measure: Postoperative Pain Management
timeFrame: 6.hour
measure: Postoperative Pain Management
timeFrame: 12.hour
measure: Postoperative Pain Management
timeFrame: 24.hour
measure: Postoperative Pain Management
timeFrame: 24 hours
measure: Postoperative Pain Management
timeFrame: 24 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: BasaksehirCamSakuraH
Study officials:
affiliation: BasaksehirCamSakuraH
name: Hilal Akça
role: PRINCIPAL_INVESTIGATOR
References: