louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT01213654: Inter Costal Catheters for Video-Assisted Thoroscopic (VATS) Lobectomy
Official title: Pain Relief After VATS Lobectomy Using Interoperatively Placed Inter Costal Catheters.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Lung Cancer Patients
Keywords: Lung cancer
VATS Lobectomy
Lead sponsor: Rigshospitalet, Denmark
Sponsor class: OTHER
Collaborators: name: Dept. of thoracic Surgery
name: Dept. of cardio-thoracic anaesthesia
name: Dept. Surgical PAthophysiology
name: all Blegdamsvej 9, 2100-Copenhagen, Denmark
First posted: 2010-10-04
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Consenting lung cancer patients due for elective surgery

Brief summary: A pilot study to observe satisfaction of analgesia with intercostal catheters after VATS lobectomy.

Detailed description: Pain and satisfaction with pain treatment is investigated in a population after VATS lobectomy.

Eligibility criteria: Inclusion Criteria:

Age of consent (ie age\>=18) Eligible for lobectomy Able to comply Willing to register postoperatively

-

Exclusion Criteria:

* do not understand DAnish

Primary outcomes:
measure: NRS (pain score 0-10))
timeFrame: Until discharge (2-4 days)
measure: satisfaction (Verbal ranking scale 1-4)
timeFrame: until discharge, 2-4 days
Secondary outcomes:
measure: Side effects (quantitatively, see details)
timeFrame: until discharge, 2-4 days
Other outcomes:
Locations:
city: Copenhagen
country: Denmark
facility: Rigshospitalet
Study officials:
References:
Clinical trial NCT06947954: Nourish Clinical Trial
Official title: Nourish Intervention Trial
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Nutrition
Healthy
Keywords: Food literacy
Cooking skills
Lead sponsor: Case Western Reserve University
Sponsor class: OTHER
First posted: 2025-04-27
Enrollment: 180
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: PREVENTION

Brief summary: The purpose of the research study is to learn more about the best ways to teach cooking and food skills to adults, and how cooking classes may help reduce one's stress and food waste, as well as improve their diet.

Detailed description: Currently, 12.8% of Americans experience food insecurity, and food insecurity is associated with elevated perceived stress. Food literacy is proficiency in food-related skills and knowledge, including food preparation and cooking skills, basic nutrition knowledge, and the ability to prevent food waste. Recent research conducted in Australia suggests that food literacy interventions are associated with improved food security. Traditionally food literacy interventions take a recipe-based approach to culinary nutrition and lack information about key components of food literacy, such as food storage and food waste reduction techniques. However, recent research by the PI contends that recipes may be difficult for food insecure individuals to implement at home, given the challenge of procuring ingredients, suggesting the need for a new approach. In addition, food insecure households face additional environmental challenges, such as owning fewer cooking utensils, compared to food secure households. Based on the Social Cognitive Theory, the Nourish intervention addresses these limitations by incorporating food waste reduction, food storage knowledge, and improvisational cooking skills (cooking with what you have on hand) into food literacy and culinary nutrition education, as well as providing key cooking utensils. Eventually, the study team plans to test the impact of the Nourish intervention on food literacy, perceived stress, diet quality and food security to determine if food literacy interventions can positively impact perceived stress, diet, and food security. The present clinical trial will test the effectiveness of the Nourish intervention on household food waste, diet quality, and food and cooking skills and behaviors.

Eligibility criteria: Inclusion Criteria:

* Age 18 and over
* Ability to attend classes in person

Exclusion Criteria:

* Non-English speaking

Primary outcomes:
measure: Food Waste Volume
timeFrame: Change from Baseline to 10 weeks post-randomization
Secondary outcomes:
Other outcomes:
Locations:
city: Cleveland
country: United States
facility: Community Recruitment
state: Ohio
Study officials:
affiliation: Case Western Reserve University
name: Melissa Prescott, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Purdue University
name: Brenna Ellison, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01558154: Comparison of Treatment Effect of Chinese Medicine and Western Medicine on Depression in China and America
Official title: Comparison of Treatment Effect of Chinese Medicine and Western Medicine on Depression in China and America
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Depression
Keywords: depression
Chinese herb
acupuncture
Psychotherapy
Transcranial magnetic stimulation
Lead sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Sponsor class: OTHER
Collaborators: name: California Pacific Medical Center Research Institute
name: Massachusetts General Hospital
First posted: 2012-03-20
Enrollment: 160
Sex: ALL
Minimum age (years): 16
Maximum age (years): 70
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: TREATMENT

Brief summary: Comparison of different assessment methods to evaluate the treatment efficacy of Chinese medicine on minor and mild depression.

Detailed description: Significant differences show on the evaluation of treatment efficacy of Chinese medicine on depression in China and America. Choose minor and mild depression patients as trials. One hundred and sixty trials will be included and randomly divided into Chinese medicine group (n=40), acupuncture group (n=40), traditional Chinese medicine psychology group (n=40) and physical treatment group (n=40). Time points of assessment are before treatment, 1 week, 2 weeks, 4weeks, 6 weeks and 12 weeks post treatment.The assessment tools are series of psychological questionnaires. And study the mechanism of treatment efficacy assessment variances by different methods.

Eligibility criteria: Inclusion Criteria:

* According with ICD-10 criteria of depression;
* Age 16-70;
* Antidepressant and other Psychiatric drugs have not been had two weeks before the trial, or the drugs above had been used but have cleaning period of two weeks;
* Level of education is higher than junior middle school;
* Course of disease is more than two weeks;
* Volunteer to join and Signed the informed consent

Exclusion Criteria:

* Pregnancy or lactation;
* Severe depression or have serious suicidal tendencies
* long distance or other causes who can not adherence to treatment

Primary outcomes:
measure: psychological questionnaires
timeFrame: 12 weeks post treatment.
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Guang'anmen Hospital
state: Beijing
Study officials:
affiliation: Guang'anmen Hospital
name: Weidong Wang, master
role: STUDY_CHAIR
References:
Clinical trial NCT00390754: Usefulness of Home Pregnancy Testing
Official title: Utility of Home Pregnancy Testing in Medicaid Women at Risk for Unintended Pregnancy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Fertility
Keywords: pregnancy
unintended
menses
Lead sponsor: Michigan State University
Sponsor class: OTHER
Collaborators: name: Michigan Department of Community Health
First posted: 2006-10-20
Enrollment: 198
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 34
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The objective of this study is to determine whether women in a Medicaid population at risk for unintended pregnancy will keep a home pregnancy test on hand and (if necessary) use it appropriately.

Detailed description: Once pregnancy is recognized, most women seek prompt prenatal care and try to stop risk behaviors. Unfortunately, women with unintended pregnancies do not recognize their pregnancies promptly, and inadvertently continue risk behaviors into the vulnerable early pregnancy weeks. Home pregnancy testing is a rapid and inexpensive means of pregnancy diagnosis. The objective of this study is to determine whether women in a Medicaid population at risk for unintended pregnancy will keep a home pregnancy test on hand and (if necessary) use it appropriately

Eligibility criteria: Inclusion Criteria:

* aged 18 to 34 year old female,
* sexually active,
* not pregnant,
* not desiring pregnancy,
* not surgically sterile,
* intercourse at least once in the past 6 months without using effective contraception (hormonal or barrier or male vasectomy)
* receiving Medicaid OR child on Medicaid OR Medicaid paid for prev. preg
* understands written/spoken English enough to give informed consent and respond to survey

Exclusion Criteria:

* fails to meet inclusion criteria

Primary outcomes:
measure: Number of episodes of use of home pregnancy test kits
timeFrame: 6 month followup
Secondary outcomes:
measure: Knowledge about use of home pregnancy test kits
timeFrame: 6 months
measure: Episodes of pregnancy suspicion
timeFrame: 6 months
Other outcomes:
Locations:
city: East Lansing
country: United States
facility: Michigan State University
state: Michigan
Study officials:
affiliation: Michigan State University
name: Mary D. Nettleman, MD, MS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Nettleman MD, Brewer JR, Ayoola AB. Self-testing for pregnancy among women at risk: a randomized controlled trial. Am J Prev Med. 2009 Feb;36(2):150-3. doi: 10.1016/j.amepre.2008.09.023. Epub 2008 Dec 5.
Clinical trial NCT00713154: Safety and Preliminary Efficacy Study of MTS-01 for the Prevention of Alopecia Induced by WHole Brain Radiotherapy
Official title: A Phase II, Double-Blind Placebo-Controlled, Parallel Group Study of the Safety and Preliminary Efficacy of MTS-01, for the Prevention of Alopecia Induced by Whole Brain Radiotherapy
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: PHASE2
Conditions: Alopecia
Keywords: Radiotherapy
induced
Lead sponsor: Mitos Pharmaceuticals
Sponsor class: INDUSTRY
First posted: 2008-07-11
Enrollment: 16
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purpose of this study is to determine if MTS-01 is effective in preventing radiotherapy-induced hair loss in patients receiving whole brain radiotherapy

Detailed description: Hair loss (alopecia) occurs commonly as a result of external beam radiotherapy to the brain, and contributes to the social isolation and distress of patients with cancer. MTS-01 is a topical gel formulation that can be applied to the scalp during delivery of radiotherapy

Eligibility criteria: Inclusion Criteria:

* is \>/= 18 years of age
* Has metastatic cancer to the brain for which palliative or prophylactic whole brain radiotherapy is recommended. A histological diagnosis of cancer will be required, however, a biopsy of the brain metastases will not be required
* Can understand and sign the IRB/IEC approved informed consent, can communicate with the Investigator, and can understand with the requirements of the protocol
* has signed the HIPAA authorization

Exclusion Criteria:

-

Primary outcomes:
measure: Investigator assessment of hair loss using a 10 point scale
timeFrame: up to 12 weeks
Secondary outcomes:
measure: A time to event analysis of the hair loss
timeFrame: up to 12 weeks
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT05923554: Treatment of Peri-implant Mucositis on Incongruous Dental Prostheses Versus Congruous
Official title: Impact of Non-surgical Treatment of Peri-implant Mucositis on Incongruous Dental Prostheses Versus Congruous on a Single Tooth Restoration
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Bleeding of Subgingival Space
Lead sponsor: University of Catania
Sponsor class: OTHER
First posted: 2023-06-28
Enrollment: 56
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: After non-randomization, patients were assigned to a group with un-congruous single-tooth prostheses and a group with congruous single-tooth prostheses. Patients received a one-stage full-mouth scaling without chlorhexidine. Clinical and microbiological examination was performed at baseline, after 1, 2, and 3 months.
Primary purpose: TREATMENT

Brief summary: The aim of the present study was to test the hypothesis that non-surgical periodontal therapy on peri-implant mucositis resolution results in a greater clinical improvement in patients with congruous versus non-congruous single dental implant restoration.

Detailed description: The aim of the present study was to test the hypothesis that non-surgical periodontal therapy on peri-implant mucositis resolution results in a greater clinical improvement in patients with congruous versus non-congruous single dental implant restoration by comparing two groups of patients with peri-implant mucositis.

Eligibility criteria: Inclusion Criteria:

* peri-implant mucositis
* bleeding on probing and/or a gingival index \<1 at least at one site at baseline
* absence of peri-implant bone loss during the last 2 years before baseline

Exclusion Criteria:

* Periodontal disease
* Systemic diseases

Primary outcomes:
measure: Bleeding on probing change % reduction
timeFrame: 6-months
Secondary outcomes:
measure: Reduction of probing depth in mm
timeFrame: 6-months
Other outcomes:
Locations:
city: Catania
country: Italy
facility: AOU Policlinico G. Rodolico
Study officials:
affiliation: Università degli Studi di Catania
name: Gaetano Isola
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06733454: REEF: Remote EEG Experiences With Families
Official title: Remote EEG Experiences With Families
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Healthy
Keywords: Pediatric EEG
Lead sponsor: New York University
Sponsor class: OTHER
First posted: 2024-12-13
Enrollment: 40
Sex: ALL
Minimum age (years): 1
Maximum age (years): 24
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Families with children 1-month to 24-months of age will be enrolled in this study.

Brief summary: The goal of this observational study is to learn about the usability of portable EEG sensors (REMI) in the home with infants and young children. The main question it aims to answer is: Can families comfortably use portable EEG sensors (REMI) in the home with their children? Families will wear the REMI sensors for an extended period of time (30 minutes to 1 week) and answer online survey questions.

Detailed description: There has been significant innovation in remote testing procedures over the past few years, accelerated in part as a result of the COVID-19 pandemic-related testing restrictions. Shifts to remote testing have included standardization of methods for survey administration and adaptations of traditional in-lab paradigms for use in remote assessments. The current project will develop and standardize a remote protocol measuring infant brain function using wireless, portable, user-friendly, single-channel EEG sensors. Infant cortical activity will be collected using the REMI (Remote EEG Monitoring System), a wireless, single-channel sensor. The sensors are applied to the head using specially designed infant-friendly adhesive stickers (to avoid skin irritation). Families of children between the ages of 1 month and 24 months will be eligible to participate in this study. Experimenters will initiate the sensors and will instruct families on how to use the REMI system independently (i.e., changing adhesive stickers when necessary). Families will then record child EEG for an extended period of time (30 minutes to 2 weeks). When recording is complete, the family will mail back all equipment to the lab.

Eligibility criteria: Inclusion Criteria:

* Child is between the ages of 1 month and 24 months of age

Exclusion Criteria:

* Child has known neurodevelopment disorder
* Legal guardian is under 18 years of age

Primary outcomes:
measure: Number of participants who independently recorded at least 30 minutes of data
timeFrame: Up to 2 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: New York
country: United States
facility: New York University
state: New York
Study officials:
References:
Clinical trial NCT01304654: ALI (Acute Lung Injury) /ARDS (Acute Respiratory Distress Syndrome) in Oncologic Pediatric Patients
Official title: Practice of Mechanical Ventilation in Pediatric Oncologic Patients Diagnosed with Acute Lung Injury / Acute Respiratory Distress Syndrome
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Acute Lung Injury
Acute Respiratory Distress Syndrome
Neoplasms
Keywords: acute lung injury
respiratory distress syndrome
neoplasms
child
Lead sponsor: Grupo de Apoio ao Adolescente e a Crianca com Cancer
Sponsor class: OTHER
First posted: 2011-02-25
Enrollment: 29
Sex: ALL
Minimum age (years): 29
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Pediatric oncologic patients

Brief summary: Identify pediatric oncologic patients with ALI/ARDS at GRAACC (Grupo de Apoio ao Adolescente e a Criança com Câncer) /IOP's (Instituto de Oncologia Pediátrica) Pediatric Intensive Care Unit and evaluate the mechanical ventilation practice in these subjects for a 48mo period.

Detailed description: Evaluate adequate mechanical ventilation based on protective ventilation protocols for children available so far.

Evaluate and describe the subjects. Evaluate the necessity and outcome of rescue therapies (surfactant, prone position, corticosteroids, alveolar recruitment) Obtain data about ALI/ARDS' etiology, mortality rates and predictive factors related to the outcomes (PICU/ hospital discharge or death)

Eligibility criteria: Inclusion Criteria:

* patients admitted at the intensive care unit with diagnosis of acute lung injury or acute respiratory distress syndrome and submitted to mechanical ventilation for over 24h

Exclusion Criteria:

* mechanical ventilation less than 24h
* absence of ALI/ARDS criteria
* no neoplasm diagnosis

Primary outcomes:
measure: Identify pediatric oncologic patients with ALI/ARDS at GRAACC's PICU and evaluate how they are mechanically ventilated
timeFrame: 2y
Secondary outcomes:
measure: Epidemiologic data about the selected patients
timeFrame: 28 days
Other outcomes:
Locations:
city: Sao Paulo
country: Brazil
facility: Grupo de Apoio ao Adolescente e à Criança com Câncer
Study officials:
affiliation: Grupo de Apoio ao Adolescente e a Crianca com Cancer
name: Rodrigo G Arduini, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06886854: Evaluation of the Impact of Rotating Posterior and Transverse Presentations At 2 Hours of Full Dilation
Official title: Evaluation of the Impact of Rotating Posterior and Transverse Presentations At 2 Hours of Full Dilation
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Fetus in Posterior or Transverse Position; Manual Rotation ; Obstetrics ; Delivery Room Practice
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2025-03-20
Enrollment: 1000
Sex: MALE
Minimum age (years): 15
Maximum age (years): 50
Standard ages: CHILD
ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Woman in labor, not delivered at 2 hours of complete dilation, with a posterior or transverse fetal presentation

Brief summary: During labor, 20% of fetuses present in a posterior or transverse position. Among them, 90% rotate spontaneously during labor. For the remaining 10%, maintaining a posterior or transverse position leads to longer labor, increased instrumental deliveries, more cesarean sections, and more severe perineal tears. Obstetricians can intervene by manually rotating the fetus to an anterior position. Several studies have shown the benefits of this technique, but they were all conducted at full dilation or one hour after full dilation. This timing does not allow enough time for the fetus to rotate spontaneously. Additionally, manual rotation can be poorly tolerated by the patient, especially if pain management is insufficient.

Our study aims to demonstrate the benefits of manual rotation two hours after full dilation. This delay allows 90% of fetuses to rotate spontaneously, and it could help harmonize obstetrical practices.


Eligibility criteria: Inclusion Criteria:

* - Patient delivering at Hospices Civils de Lyon (XR, HFME, LS?)
* Low-pitched voice agreement
* Mobile fetal cephalic presentation
* Transverse or posterior presentation confirmed by ultrasound
* 2 hours of complete dilation
* Agreement for 3 hours by OB-GYN
* Normal fetal heart rate
* Epidural anesthesia in place
* Bladder catheterized

Exclusion Criteria:

* - Multiparous uterus with scars
* Breech presentation
* Fetus \> 5000 g
* Patient refusal
* Inadequate analgesia
* Fetal hypoxia

Primary outcomes:
measure: Rate of eutocic deliveries
timeFrame: Collected at the time of delivery.
Secondary outcomes:
Other outcomes:
Locations:
city: France
country: France
facility: Hopital de la croix rousse
city: France
country: France
facility: Hopital Femme Mere Enfant
Study officials:
References:
Clinical trial NCT06632054: Use of Text Messaging Reminders to Increase FIT Completion Among Patients at the NYU FHCs
Official title: Use of Text Messaging Reminders to Increase FIT Completion Among Patients at the New York University (NYU) Family Health Centers (FHCs)
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Colon Cancer
Lead sponsor: NYU Langone Health
Sponsor class: OTHER
First posted: 2024-10-08
Enrollment: 764
Sex: ALL
Minimum age (years): 45
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Adult patients (ages 45-75) eligible for FIT at a Family Health Center clinic (excluding Flatbush locations).

Brief summary: The research team will compare the efficacy of targeted text message reminders against currently used phone call reminders at increasing patient completion of fecal immunochemical test (FIT) for colon cancer screening.


Eligibility criteria: Inclusion Criteria:

* Adult patients (ages 45-75) eligible for FIT at a Family Health Center clinic (excluding Flatbush locations).

Exclusion Criteria:

* See inclusion criteria.

Primary outcomes:
measure: FIT Completion at 7 Days Post-FIT Test Order
timeFrame: Day 7 Post-Visit
measure: FIT Completion at 14 Days Post-FIT Test Order
timeFrame: Day 14 Post-Visit
measure: FIT Completion at 21 Days Post-FIT Test Order
timeFrame: Day 21 Post-Visit
Secondary outcomes:
measure: Total Time to Completion of FIT Test
timeFrame: Up to Day 21 Post-Visit
Other outcomes:
Locations:
city: New York
country: United States
facility: NYU Langone Health
state: New York
Study officials:
affiliation: NYU Langone Health
name: Leora Horwitz, MD, MHS
role: PRINCIPAL_INVESTIGATOR
References: