Clinical trial NCT03934645: Comparison of Delirium Evaluation Tools Effectiveness in Intensive Care Patients
Official title: Comparison of Efficacy of "Pre-deliric Version 1-2, E-predeliric Score and ICDSC" Tests Used in the Diagnosis of Delirium in Intensive Care Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Delirium
Keywords: delirium
Intensive Care Delirium Screening Checklist (ICDSC)
intensive care unit (ICU)
Delirium prediction model for ICU patients version 1
Delirium prediction model for ICU patients version 2
Early prediction model for delirium in ICU patients
sensitivity
specificity
Lead sponsor: Trakya University
Sponsor class: OTHER
First posted: 2019-05-02
Enrollment: 250
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: In our study, 250 patients hospitalized more than twenty-four hours in the anesthesia intensive care unit of Trakya University Medical Faculty between 01 November 2017 and 01 November 2019 were accepted.

Brief summary: This study compares the efficacy of scoring models used in delirium prediction in patients applying to intensive care unit. The diagnosis of delirium is based on the Intensive Care Delirium Screening Checklist (ICDSC). The aim of this study is determine the sensitivity and specificity of three prediction models (Delirium prediction model for ICU patients version 1 \[Predeliric version-1\], Delirium prediction model for ICU patients version 2 \[Predeliric version-2\] and Early prediction model for delirium in ICU patients \[E-Predeliric\]).

Detailed description: Most patients in the intensive care unit (ICU) are entered delirium during hospitalization. Delirium; has been reported that it is associated with significant side effects such as prolonged stay in hospital and intensive care unit, increased morbidity and mortality and high costs. For evaluating delirium in intensive care units; There are several assessment tools such as the Intensive Care Delirium Screening Checklist(ICDSC) etc. The ICDSC checklist is an eight-item screening tool that is based on DSM criteria and applied with data that can be collected through medical records. Its validity has been confirmed by several studies. Assessment tools such as ICDSC; can diagnose after patient is entered the delirium and therefore cannot provide early treatment and preventive measures. Prevention of delirium is more important than the correct treatment of delirium. For preventing delirium; early diagnosis and treatment are necessary. Pre-deliric (DELIRIUM PREDICTION MODEL FOR INTENSIVE CARE PATIENTS) and E-pre-deliric (EARLY PREDICTION MODEL FOR DELIRIUM IN ICU PATIENTS) prediction models; are developed and approved for delirium estimation in intensive care unit patients.

Data of the patient in the first 24 hours of admission to the intensive care unit are collected and the delirium prediction score is found by the pre-deliric model. In the e-pre-deliric model, delirium prediction score is determined by inputting the data of the patient in admission to the intensive care unit.

In this study; the definition of delirium was done by ICDSC scoring. Patients with an ICDSC score of 4 and over were diagnosed with delirium.

The aim of this study; To determine the sensitivity and specificity of E-pre-deliric and Pre-deliric scores by comparing the effectiveness of ICDSC, E-pre-deliric, Pre-deliric version-1 and Pre-deliric version-2 assessment tools in the prediction of delirium.

Eligibility criteria: Inclusion Criteria:

* Patients hospitalized in the intensive care unit for more than 24 hours
* Patients 18 years and older
* Patients without mental disability
* Non-pregnant patients

Exclusion Criteria:

* Patients hospitalized in the intensive care unit for less than 24 hours
* Patients under 18 years
* Patients in coma during hospitalization in the intensive care unit
* Patients with aphasia disease, who cannot communicate
* If the compliance rate of the delirium screening was \<%80 during a patient's stay in the ICU
* If signs of delirium are seen within 24 hours of ICU admission

Primary outcomes:
measure: Rate of Predeliric version-1 model
timeFrame: 1 day in admission (1 time)
measure: Rate of Predeliric version-2 model
timeFrame: 1 day in admission (1 time)
measure: Rate of E-predeliric model
timeFrame: 1 day in admission (1 time)
Secondary outcomes:
measure: ICDSC score
timeFrame: 1 time per day during hospitalization
Other outcomes:
Locations:
city: Edirne
country: Turkey
facility: Trakya University
state: Centrum
Study officials:
affiliation: Trakya University
name: DİLEK MEMİŞ, Proffesor
role: PRINCIPAL_INVESTIGATOR
References: