Clinical trial NCT04499300: Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age
Official title: Elderly Patients and COVID-19 Infection: a Cohort of Fifty Patients Over Ninety Years of Age
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Covid19
Lead sponsor: Brugmann University Hospital
Sponsor class: OTHER
First posted: 2020-08-05
Enrollment: 50
Sex: ALL
Minimum age (years): 90
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Same as inclusion criteria

Brief summary: SARS-CoV2 or CoVid19 disease is a newly described pathology linked to a subtype of the coronavirus family identified in China in December 2019. This pathology can present multiple clinical facets, ranging from asymptomatic forms to more commonly critical pulmonary forms called "Acute Respiratory Distress Syndrome". The elderly population is more at risk for this infection due to the senescence of the immune system, co-morbidities and poly medications. They also often present a greater state of fragility.

This study aims to report the epidemiology of the first 50 patients over 90 years of age hospitalized within the CHU Brugmann hospital.


Eligibility criteria: Inclusion Criteria:

* Be over 90 years of age on the date of admission to CHU Brugmann Hospital
* Have a SARS Cov2 infection proven by antigen or RT-PCR on smear and / or typical imaging regardless of the clinical manifestation
* Have been hospitalized at CHU Brugmann between 03/01/2020 and 05/10/2020

Exclusion Criteria:

None

Primary outcomes:
measure: Demographic data
timeFrame: 5 minutes
measure: Comorbidities
timeFrame: 5 minutes
measure: Cumulative Illness Rating Scale-Geriatric (CIRS-G)
timeFrame: 5 minutes
measure: Treatments
timeFrame: 5 minutes
measure: Signs and symptoms
timeFrame: 5 minutes
measure: Fever
timeFrame: 5 minutes
measure: Hypoxemia
timeFrame: 5 minutes
measure: Tachycardia
timeFrame: 5 minutes
measure: Hypotension
timeFrame: 5 minutes
measure: Gasometry
timeFrame: 5 minutes
measure: Infectious data
timeFrame: 5 minutes
measure: Blood count
timeFrame: 5 minutes
measure: Ionogram
timeFrame: 5 minutes
measure: Liver function
timeFrame: 5 minutes
measure: Coagulation
timeFrame: 5 minutes
measure: Renal function
timeFrame: 5 minutes
measure: Albumin
timeFrame: 5 minutes
measure: CRP
timeFrame: 5 minutes
measure: Fibrinogen
timeFrame: 5 minutes
measure: D-dimers at hospital admission or first recorded
timeFrame: 5 minutes
measure: NTproBNP
timeFrame: 5 minutes
measure: CK
timeFrame: 5 minutes
measure: Troponin
timeFrame: 5 minutes
measure: Ferritin
timeFrame: 5 minutes
measure: Procalcitonin
timeFrame: 5 minutes
measure: Biology - highest rate
timeFrame: 5 minutes
measure: Biology - lowest rate
timeFrame: 5 minutes
measure: Percentage of pulmonary involvement on chest CT scan
timeFrame: 5 minutes
measure: Number of pulmonary lobes affected
timeFrame: 5 minutes
measure: Type of lesions
timeFrame: 5 minutes
measure: Need for oxygenotherapy
timeFrame: 5 minutes
measure: Means of ventilation
timeFrame: 5 minutes
measure: Treatment received
timeFrame: 5 minutes
measure: Length of ICU Stay
timeFrame: 5 minutes
measure: Status at hospital exit
timeFrame: 5 minutes
measure: Mortality
timeFrame: 5 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Brussels
country: Belgium
facility: CHU Brugmann
Study officials:
References: