Clinical trial NCT06921447: Evaluating Decision-making Using ChatGPT-4 Among Trainees in Surgery
Official title: Evaluating ChatGPT-4 as a Decision-Making Support Tool for Surgical Trainees
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Artificial Intelligence (AI)
Training
Surgery
Keywords: artificial intelligence
surgery
training
oncology
emergency
Lead sponsor: Ospedali Riuniti Trieste
Sponsor class: OTHER
First posted: 2025-04-10
Enrollment: 35
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population will consist of general surgery trainees and faculty members from a single academic surgical department. Participants will be stratified into three groups based on their level of training and experience: Junior Residents: Postgraduate Year (PGY) 1-2; Senior Residents: PGY 3 and above; Attending Surgeons: Board-certified general surgeons with independent clinical practice

Brief summary: This study aims to assess whether ChatGPT-4 can support surgical trainees in clinical decision-making. By comparing the performance of ChatGPT-4 with junior residents, senior residents, and attending surgeons on standardized clinical scenarios, the study seeks to understand the potential role of large language models in surgical education. The ultimate goal is to evaluate whether ChatGPT-4 can be safely integrated as a supplementary educational tool to aid junior residents in developing critical thinking and surgical judgment.

Detailed description: Background:

Artificial Intelligence (AI) is rapidly transforming the medical landscape, offering new possibilities in education, diagnostics, and decision support. In surgery, clinical decision-making is a core competency developed progressively through training. ChatGPT-4, a state-of-the-art large language model developed by OpenAI, has demonstrated competence in handling medical queries and clinical reasoning tasks. However, its performance in complex surgical decision-making compared to human trainees remains largely unexplored.

Objective:

The EDuCATe study aims to evaluate the accuracy and reliability of ChatGPT-4's responses to clinical scenarios involving general surgery cases. Specifically, the study compares the model's performance to that of junior residents, senior residents, and attending surgeons to understand if ChatGPT-4 can serve as a safe and effective educational tool for surgical trainees.

Methods:

Seven clinical scenarios will be constructed using real anonymized patient data representing common general surgery conditions. Each case will be presented step-by-step, mimicking the clinical decision-making process. Participants will answer a question related to treatment choice.

Participants will include junior residents (PGY1-2), senior residents (PGY3+), and attending surgeons from a single surgical department. ChatGPT-4 will be prompted with the same scenarios. All participants will be instructed to complete the cases without using external resources such as AI tools or internet searches, relying solely on their clinical knowledge.

Statistical analysis will compare performance across groups using non-parametric tests (e.g., Wilcoxon rank sum).

Expected Outcomes:

The study hypothesizes that ChatGPT-4 will perform at a level comparable to senior residents or attending surgeons and outperform junior residents in decision-making. If confirmed, these results could support the safe use of ChatGPT-4 as a training aid for junior surgical residents, potentially improving educational outcomes and clinical reasoning skills.

Significance:

This study will provide novel insight into the role of AI in surgical education. By rigorously comparing ChatGPT-4's decision-making capabilities to that of human surgeons at various levels, the study hopes to define its utility, limitations, and appropriate use in residency training programs.

Eligibility criteria: Inclusion Criteria:

* Actively enrolled or employed in the general surgery residency or department at the participating institution
* Willingness to participate and complete all clinical case scenarios
* Consent to participate in the study

Exclusion Criteria:

* Incomplete responses
* Use of external assistance (e.g., internet search, AI tools) when answering scenarios, as self-reported in instructions

Primary outcomes:
measure: Proportion of correct responses
timeFrame: Baseline
Secondary outcomes:
measure: Comparison of accuracy across experience levels
timeFrame: Baseline
measure: Confidence level
timeFrame: Baseline
measure: Percentage of use of AI for clinical cases evaluation
timeFrame: Baseline
Other outcomes:
Locations:
city: Trieste
country: Italy
facility: University of Trieste
Study officials:
References: