Clinical trial NCT02550951: Utility of MR Lymphangiography in Postoperative Follow-up of Lymphedema: Comparison With Lymphoscintigraphy
Official title: Utility of Magnetic Resonance Lymphangiography in Postoperative Follow-up of Lymphedema: Comparison With Lymphoscintigraphy
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Lymphedema
Lead sponsor: Seoul National University Hospital
Sponsor class: OTHER
First posted: 2015-09-16
Enrollment: 7
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: Its usefulness in implementing magnetic resonance angiography for postoperative follow-up of lymph lymphedema should try to evaluate and compare lymphoscintigraphy.

Detailed description: Surgical methods include " surgical procedure to make a good lymphatic drain 'and' surgical resection with lymph tissue swelling , significant that two of lymphedema .In recent years, began receiving the spotlight this former method using micro-surgery , inde essential that in order to increase the success rate of these micro-surgery accurately assess the structural abnormalities of preoperative lymphatic and establishing the surgical plan , the primary diagnostic imaging examination of existing lymphedema Since the nuclear medicine examination as to obtain an accurate anatomical information it is also ideal for imaging in the preoperative assessment of lymphedema is precisely that you can not .

In contrast magnetic resonance lymphangiography recently developed a new magnetic resonance imaging techniques that many advantages in precision assessment of lymphedema patients.

First, there are high spatial resolution magnetic resonance lymphangiography through the lymphatic vessels to obtain the correct anatomical information .

Second, magnetic resonance lymphangiography is provide not only information about the functional status of the lymphatic anatomical information .

Third, the magnetic resonance lymphangiography minimally invasive techniques , without exposure to radiation , is relatively easy and safe , that there is a great advantage of being able to diagnose the structural and functional at the same time or later in lymphatic vessels.

The magnetic resonance lymphangiography via the lymphatic advantage given also helps to establish a specific treatment plan , as well as accurate preoperative diagnosis of lymphedema that may contribute to enhance the success of micro-surgery.

Eligibility criteria: Inclusion Criteria:

* At least 20 years of age
* Patients underwent preoperative and receive magnetic resonance lymphangiography and Lymphoscintigraphy At the postoperative 3 months

Exclusion Criteria:

* Patients with a history of adverse effects on magnetic resonance contrast agents
* Patients with a Decreased renal function(Glomerular filtration rate \<30 mL / min)
* Other, maternity, patients with a pacemaker or a cochlear

Primary outcomes:
measure: pattern of lymph drainage (Scale of 0 to 5)
timeFrame: After magnetic resonance lymphangiography scans in up to 2years
measure: delay of lymph drainage (Scale of 0 to 10)
timeFrame: After magnetic resonance lymphangiography scans in up to 2years
measure: depiction of lymph vessels (Scale of 0 to 10)
timeFrame: After magnetic resonance lymphangiography scans in up to 2years
measure: enhancement of inguinal lymph nodes (Scale of 0 to 10)
timeFrame: After magnetic resonance lymphangiography scans in up to 2years
measure: Visibility of Lymphatic Duct (Scale of 0 to 10)
timeFrame: After magnetic resonance lymphangiography scans in up to 2years
Secondary outcomes:
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
Study officials:
affiliation: Seoul National University Hospital(Radiology)
name: SeungHong Choi, MD,PhD
role: PRINCIPAL_INVESTIGATOR
References: