Clinical trial NCT03693053: Socioeconomic Deprivation and Peripheral Arterial Disease
Official title: Assessment of the Level of Precariousness in a Population of Patients With Symptomatic Peripheral Arterial Disease.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Peripheral Arterial Disease
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
First posted: 2018-10-02
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients were recruited from

* Vascular medicine and surgery department of Grenoble university hospital
* Or therapeutic education consultation. These consultations took place in Grenoble reference center of therapeutic education CREPvAL Granted as part of education program: "On the move! Better understand and better live your PAD".

Brief summary: Atherosclerosis is a systemic disease that affects coronary, cerebral, and lower-extremity arteries. Peripheral artery disease (PAD) is the manifestation of atherosclerosis in the legs. Three different stages can be found: asymptomatic stage (stage 1), exercise ischemia stage (stage 2) and rest ischemia stage (stage 3). The risk factors for PAD are similar to those for coronary artery disease (CAD) and cerebrovascular disease (CBVD), like high blood pressure, diabetes, smoking, dyslipidemia and obesity. But cigarette smoking is the single most important risk factor for the development and progression of PAD.

PAD is a serious illness and an important predictor of cardiovascular disease with major medico-economic consequences.

A low socioeconomic status (SES) is associated with higher cardiovascular mortality and morbidity. In these vulnerable populations, there is an increase in the prevalence of cardiovascular risk factors, particularly for smoking.

The main objective of this study was to assess the level of precariousness in patients with symptomatic PAD and compare it to the level of precariousness in the general population.

Patients were recruited from vascular medicine and surgery department of Grenoble university hospital or therapeutic education outpatient consultation.

The analysis of socio-economic and environmental data resulted in:

- EPICES score: (Evaluation of the Deprivation and Inequalities of Health in Healthcare Centers score). The EPICES score is a quick and validated questionnaire to assess precariousness at the individual level, developed by considering all the material and psychosocial dimensions of precariousness.

Precariousness, according to the EPICES score, in the general population is estimated at 40%.

- INSEE parameters. The investigators completed the EPICES score with more traditional indicators derived from The National Institute of Statistics and Economic Studies (INSEE) collects, analyses and disseminates information on the French economy and society. The investigators collected the level of education and professional practice based on the nomenclature of socio-professional categories defined by INSEE.

Cardiovascular risk factors were also collected to measure the links between the level of precariousness and cardiovascular risk factors.


Eligibility criteria: Inclusion Criteria:

* Male or female,
* Age 18 years or older,
* Symptomatic PAD (stage 2 or 3)

Exclusion Criteria:

* Pregnant woman
* Person under administrative or judicial supervision

Primary outcomes:
measure: Level of precariousness in patients with symptomatic PAD
timeFrame: one day
Secondary outcomes:
measure: Level of precariousness by EPICES score between stage 2 and stage 3 of symptomatic PAD.
timeFrame: one day
measure: Links between the level of precariousness by EPICES score and cardiovascular risk factors.
timeFrame: one day
Other outcomes:
Locations:
city: Grenoble
country: France
facility: University Hospital
state: Isere
Study officials:
References: