Clinical trial NCT06742775: Evolution of the Relationship Between Central and Peripheral Arterial Wave Velocities as a Function of Age
Official title: Evolution of the Relationship Between Central and Peripheral Arterial Wave Velocities as a Function of Age
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Aging
Diagnostic Techniques, Cardiovascular
Keywords: photoplethysmography
electrocardiography
inductive plethysmography
Pulse Wave Velocity
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
Collaborators: name: University Grenoble Alps
First posted: 2024-12-19
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 60 healthy volunteers: 3 groups of 20 volunteers per age category (under 30, between 30 and 50, over 50)

Brief summary: Acquisition of synchronized cardiovascular signals from non-invasive measurements (ECG, photoplethysmography pulse sensors, inductance plethysmography) in healthy volunteers aged from 18 to 75, during spontaneous ventilation with apneas (20 seconds) for a total acquisition time of 30 minutes.


Eligibility criteria: Inclusion Criteria:

* Men and women between 18 and 75 years of age
* No acute cardiovascular pathologies less than 2 years old,
* No chronic cardiovascular pathologies.
* Stature compatible with the use of the plethysmography T-shirt.
* Person affiliated to a social security scheme or beneficiary of such a scheme
* Signed informed consent form

Exclusion Criteria:

* Persons covered by articles L1121-5 to L1121-8 of the CSP (corresponding to all protected persons: pregnant women, parturients, nursing mothers, persons deprived of their liberty by judicial or administrative decision, persons under psychiatric care under articles L. 3212-1 and L. 3213-1 who are not covered by the provisions of article L. 1121-8, persons admitted to a health or social establishment for purposes other than research, minors, persons under legal protection or unable to express their consent).
* Personnel with a hierarchical link to the principal investigator
* Subjects excluded from another study,

Primary outcomes:
measure: Electrocardiogram
timeFrame: 1 hour
measure: Photoplethysmography
timeFrame: 1 hour
measure: inductive plethysmography
timeFrame: 1 hour
Secondary outcomes:
measure: link between peripheral and central pulse wave velocity
timeFrame: 1 hour
Other outcomes:
Locations:
city: Grenoble
country: France
facility: Laboratoire TIMC
Study officials:
affiliation: University Grenoble Alpes
name: Stéphane TANGUY
role: PRINCIPAL_INVESTIGATOR
References:
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