Clinical trial NCT06230718: EMG Analysis in ABI: Motor Imagery and Action
Official title: Upper Limb Electromyographic Response to Motor Imagery and Action Observation in Acquired Brain Injury Patients.
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Stroke
Quality of Life
Mirror Movement
Keywords: Stroke rehabilitation
Electromyography
Neuroplasticity
Upper Linb
Neurorehabilitation
Lead sponsor: University of Salamanca
Sponsor class: OTHER
First posted: 2024-01-30
Enrollment: 28
Sex: ALL
Minimum age (years): 18
Maximum age (years): 99
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study focuses on electromyographic analysis of upper limb muscle activation in stroke survivors during Motor Imagery (MI) and Action Observation (AO) rehabilitation techniques. By measuring muscle activity in the wrist and finger flexors and extensors, the research seeks to understand the impact of MI and AO on motor function recovery post-stroke. Conducted at the University of Salamanca, the study involves stroke survivors participating in a series of three experimental sessions. The analysis will correlate electromyographic responses with functional independence, limb functionality, and cognitive factors. The research aims to contribute to the fields of occupational therapy and physiotherapy, offering insights into effective rehabilitation methods for improving quality of life in stroke survivors.

Detailed description: This study investigates muscle activation in the upper limbs of stroke survivors using electromyographic analysis during Motor Imagery (MI) and Action Observation (AO). Stroke, a major cause of disability, often results in motor impairments in the upper limb, impacting daily activities. The research focuses on innovative rehabilitation techniques based on neuroplasticity, such as MI and AO, stimulated by the discovery of mirror neurons.

The primary goal is to record upper limb muscle activation during MI and AO, using surface electromyography to measure activation in wrist and finger flexors and extensors. The study will also explore the relationship between electromyographic responses and factors like daily activity independence, limb functionality, quality of life, mental evocation ability, and cognitive impairment.

Conducted at the University of Salamanca, the study will recruit stroke survivors for a three-session experimental protocol involving control, MI, and AO conditions. Data will be analyzed with SPSS Statistics, ensuring anonymity and ethical compliance. The research aims to enhance understanding of effective neurorehabilitation techniques, contributing to the fields of occupational therapy and physiotherapy.

Eligibility criteria: Inclusion Criteria:

* Being over 18 years of age
* Diagnoses of established stroke
* Present limitations or motor response deficiencies in the upper limb
* Maintain cognitive functions with the ability to follow the instructions of the interventions and evaluations (MOCA\>14)

Exclusion Criteria:

* Diagnosed with mental illness before the stroke
* Other systemic conditions on the central nervous system
* Cardiorespiratory system pathologies in severe cases
* Acute period, fever, muscle inflammation or myopathies
* Any type of vascular and organic insufficiency
* Liver disease or skin lesions in the area of application of the electrodes.

Primary outcomes:
measure: Disability and Dependence Level - Barthel Index
timeFrame: Administered once, typically taking a few minutes.
measure: Upper Limb Functionality - Action Research Arm Test (ARAT)
timeFrame: Administration time ranges from 5 to 15 minutes.
measure: Cognitive Impairment - Montreal Cognitive Assessment (MoCA)
timeFrame: takes about 10 minutes for administration.
measure: Perception Impairment - Loewenstein Occupational Therapy Cognitive Assessment (LOTCA)
timeFrame: Duration varies based on the number and type of subtests administered.
measure: Mental Evocation Ability - Mental Evocation of Images, Movements, and Activities Questionnaire (CEMIMA)
timeFrame: Duration varies
measure: Quality of Life Perception - Stroke Impact Scale 16 (SIS-16)
timeFrame: 5-10 minutes.
measure: Electromyographic Activity During MI and AO
timeFrame: during the experimental setup
Secondary outcomes:
measure: Age
timeFrame: 1 minute
measure: gender
timeFrame: 1 minute
measure: Marital Status
timeFrame: 1 minute
measure: Education Level
timeFrame: 1 minute
measure: Economic Status
timeFrame: 1 minute
measure: Affected Side
timeFrame: 1 minute
measure: Dominant Side
timeFrame: 1 minute
measure: Type of Lesion
timeFrame: 1 minute
measure: Time Since Injury
timeFrame: 1 minute
Other outcomes:
Locations:
city: Salamanca
country: Spain
facility: Universidad de Salmanca
Study officials:
References: