Clinical trial NCT06386354: Residual Neuromuscular Block in the Post-Anesthetic Unit and Postoperative Complications
Official title: Residual Neuromuscular Block in the Post-Anesthetic Unit and Postoperative Complications
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Postoperative Neuromuscular Block
Postoperative Complications
Keywords: General Anesthesia
Neuromuscular block
Lead sponsor: Dr. Negrin University Hospital
Sponsor class: OTHER
First posted: 2024-04-26
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients undergoing surgical intervention under general anesthesia that requires the use of neuromuscular block during the study time.

Brief summary: The use of neuromuscular blockers (NMB) is essential to optimize surgical conditions, ensure patient immobility during the intervention and prevent complications derived from involuntary movements. Intraoperative monitoring of neuromuscular relaxation allows the depth of neuromuscular blockade to be accurately evaluated, guaranteeing ideal conditions for the surgical team. Residual neuromuscular blockade (RNMB) is the persistence of muscle paralysis after the administration of NMB during a surgical intervention. The appearance of RNMB poses substantial challenges in the postoperative period, as it has negative repercussions for the safety and well-being of the patient.

Detailed description: The use of neuromuscular blockers (NMB) is essential to optimize surgical conditions, ensure patient immobility during the intervention and prevent complications derived from involuntary movements. Intraoperative monitoring of neuromuscular relaxation allows the depth of neuromuscular blockade to be accurately evaluated, guaranteeing ideal conditions for the surgical team. Residual neuromuscular blockade (RNMB) is the persistence of muscle paralysis after the administration of NMB during a surgical intervention. The appearance of RNMB poses substantial challenges in the postoperative period, as it has negative repercussions for the safety and well-being of the patient. In this prospective observational study, all patients who underwent general anesthesia with neuromuscular blockade were studied consecutively for one month to evaluate the presence of residual neuromuscular blockade and its potential consequences during hospital admission. .

Eligibility criteria: Inclusion Criteria:

* Patient undergoing surgical intervention under general anesthesia that requires the use of neuromuscular block during the study time and that required hospital admission.
* Informed consent signature.

Exclusion Criteria:

* Neuromuscular disease
* Not having received neuromuscular block during the intervention
* Admission to the outpatient surgery unit
* Admission to the postoperative intensive care unit
* Patients who signed informed consent, but postoperative data could not be collected upon arrival at the PACU.

Primary outcomes:
measure: Residual Neuromuscular Block
timeFrame: 5 minutes postoperatively
measure: Residual Neuromuscular Block
timeFrame: 8 minutes postoperatively
Secondary outcomes:
measure: Postoperative complications
timeFrame: 30 days postoperatively
Other outcomes:
Locations:
city: Las Palmas De Gran Canaria
country: Spain
facility: Hospital Universitario de Gran Canaria Doctor Negrín
state: Las Palmas
city: Las Palmas De Gran Canaria
country: Spain
facility: Ángel Becerra
state: Las Palmas
Study officials:
References: