Clinical trial NCT05338918: Effect of Mental Imagery on Lower Limb Functions in Stroke
Official title: Effects of Mental Imagery With Virtual Reality Training on Lower Limb Functions in Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: Lower limb
Impairment
Mental practice
Virtual Reality training
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-04-21
Enrollment: 28
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study aims to compare the effects of mental imagery and virtual reality training with virtual reality alone on lower limb functional status of stroke patients. The study will be a randomized controlled trial. After the initial evaluation randomization will be done on participants lying under the eligibility criteria. Randomized participants will be allocated to Control \& Experimental groups. Mental imagery (Audiotape recordings of some specific tasks for lower limb functions) with Virtual reality training given to experimental group while Virtual reality training alone to Control group. Task oriented training for balance \& gait as baseline treatment will be given to each group.

Detailed description: Stroke causes inability to perform activities with affected limbs among which difficulty in walking and doing house chores are the most common dysfunctions. Stroke highly affects the productivity of people in family as well as in community. It also adds financial burden on families of patients. There are number of different restorative techniques and therapeutic approaches for the rehabilitation of stroke patients. For example, bobath approach, constrained induced movement therapy, mirror therapy, electrical stimulations, Circuit training, resistance training, Motor relearning program, proprioceptive neuromuscular facilitation, body weight supported treadmill for walking, Frenkel's exercises, repetitive task specific training, electromyography biofeedback and many others. All these approaches mainly focused on the repetition of tasks to perform a specific function, as the neuroplasticity requires repetition to occur. But there is a lack of interest, motivation and attention of stroke patients to perform similar tasks repeatedly. The lack of active participation directly or indirectly affects the neural stimulation and neural plasticity. One of the most emerging techniques in these days is Mental Imagery. Mental imagery(MI) is "a training method where imagination of movements, without actually moving, is used with the intention of improving motor performance" Currently Mental imagery has been used for neuro rehabilitation as it activates the same brain areas required for planning and execution of movements more or less in the same way require for actual performance of that movement. In this study the combination for Mental imagery and virtual reality is used for participation of patients in rehabilitation program which in turn increases the neural stimulation and causes neural plasticity to improve the motor performance. By increasing the functional activity, their ADL's can be improved to help them in becoming the active member of the society.

Eligibility criteria: Inclusion Criteria:

* Patients with sub-acute/ chronic stroke (\>3 months)
* Modified Ashworth Ranking Scale 1-3
* Montreal Cognitive Assessment scoring \>24-30

Exclusion Criteria:

* Any active pathological condition
* Visual or hearing impairment
* Neurological conditions like Epilepsy, Parkinson, Alzheimer's, Impaired cognition
* Orthopedic issues hindering Mobility Substantially (Fractures, Severe Degenerative Joint Diseases etc.)
* Psychological issues

Primary outcomes:
measure: Fugl Meyer Assessment Scale - Lower Extremity
timeFrame: 6 weeks
measure: Berg Balance Scale
timeFrame: 6 weeks
measure: Timed Up and Go test
timeFrame: 6 weeks
measure: 10-meter walk test
timeFrame: 6 weeks
measure: Wisconsin Gait Scale
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Railway General Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Arshad Nawaz Malik, PhD
role: PRINCIPAL_INVESTIGATOR
References: