Clinical trial NCT05757518: Post-exercise Recovery of DOMS in Recreational Athletes
Official title: Cryosauna for Post-exercise Recovery of Delayed Onset Muscle Soreness (DOMS) in Recreational Athletes: a Randomized Control Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Injury;Sports
Keywords: DOMS
injury prevention
performance
muscle properties
Lead sponsor: Wroclaw University of Health and Sport Sciences
Sponsor class: OTHER
Collaborators: name: Gdansk University of Physical Education and Sport
First posted: 2023-03-07
Enrollment: 36
Sex: ALL
Minimum age (years): 20
Maximum age (years): 26
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized controlled trial
Primary purpose: SCREENING

Brief summary: The main goal of this study was to investigate the effectiveness of cryo-sauna in preventing the development of DOMS in the lower extremity. The second goal is to analyze the rate of regenerative changes in the right muscles after acute fatigue-induced exercises.

Detailed description: The main goal of this study was to investigate the effectiveness of cryo-sauna in preventing the development of DOMS in the lower extremity. The second goal is to analyze the rate of regenerative changes in the right muscles after acute fatigue-induced exercises.

This study design was a randomized, controlled single-blind trial with repeated measures. Moreover, the design was prepared according to the Consolidated Standards of Reporting Trials (CONSORT) for pragmatic trials. Participants were assigned into two groups: (1) experimental group (CRYO, n =16) - cryostimulation using a cryo sauna; and (2) control group (CONT, n = 15) - without any intervention. This study was conducted in the Physical Exercise Laboratory. Both groups, CRYO and CON performed a fatigue-induced protocol consisting of counter-movement jumps (CMJ) (10 set for 10 repetitions). After the fatigue exercises, only CRYO underwent cryo sauna intervention including entry immediately after, 24, 48, and 72 hours post-exercise. The order of measurements at baseline included: blood sample testing (creatine kinase, myoglobin, leukocytes) and muscle stiffness of the lower extremity. All measurements we collected at baseline, immediately post, 24, 48, 72, and 96 hours post-exercise.

Eligibility criteria: Inclusion Criteria:

* no previous experience with cryostimulation using a cryo-sauna,
* recreational lifestyle.

Exclusion Criteria:

* Current or prior pain or injury in the lower extremity.
* Previous history of surgery in the lower extremity.
* Cardiovascular disabilities.

Primary outcomes:
measure: Measurement of muscle stiffness in the lower extremity.
timeFrame: Change from baseline muscle stiffness at 96 hours after fatigue-induced exercise.
measure: Measurement of blood markers.
timeFrame: Change from baseline leukocytes concentration at 96 hours after fatigue-induced exercise.
measure: Measurement of blood markers.
timeFrame: Change from baseline creatine kinase concentration at 96 hours after fatigue-induced exercise.
measure: Measurement of blood markers.
timeFrame: Change from baseline myoglobin concentration at 96 hours after fatigue-induced exercise.
Secondary outcomes:
Other outcomes:
Locations:
city: Gdańsk
country: Poland
facility: Physical Exercise Laboratory
Study officials:
affiliation: University School of Physical Education in Wrocław
name: Sebastian Klich, Dr.
role: STUDY_DIRECTOR
References:
citation: Klich S, Krymski I, Michalik K, Kawczynski A. Effect of short-term cold-water immersion on muscle pain sensitivity in elite track cyclists. Phys Ther Sport. 2018 Jul;32:42-47. doi: 10.1016/j.ptsp.2018.04.022. Epub 2018 May 1.
citation: Klich S, Ficek K, Krymski I, Klimek A, Kawczynski A, Madeleine P, Fernandez-de-Las-Penas C. Quadriceps and Patellar Tendon Thickness and Stiffness in Elite Track Cyclists: An Ultrasonographic and Myotonometric Evaluation. Front Physiol. 2020 Dec 14;11:607208. doi: 10.3389/fphys.2020.607208. eCollection 2020.
citation: Kons RL, Orssatto LBDR, Sakugawa RL, da Silva Junior JN, Diefenthaeler F, Detanico D. Effects of stretch-shortening cycle fatigue protocol on lower limb asymmetry and muscle soreness in judo athletes. Sports Biomech. 2023 Sep;22(9):1079-1094. doi: 10.1080/14763141.2020.1779335. Epub 2020 Jul 9.