Clinical trial NCT01033006: Axillary Plexus Block in a High Resolution MRI
Official title: Axillary Plexus Block in a High Resolution MRI
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Nerve Block
Magnetic Resonance Imaging
Keywords: Peripheral Nerves
Axillary Block
MRI
Lead sponsor: Diakonhjemmet Hospital
Sponsor class: OTHER
Collaborators: name: Oslo University Hospital
First posted: 2009-12-16
Enrollment: 45
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: Background and aims:

Magnetic resonance imaging (MRI) has proved beneficial for presenting anatomy for regional anaesthesia and to demonstrate spread of local anaesthetic.

A new axillary plexus block with a triple injection (1), combining a short axillary catheter method with a transarterial axillary block, is now being evaluated with a 3 Tesla MRI. In this study, the investigators are investigating MR visualisation of three different block techniques and compare the clinical efficacy of the techniques, with the MR findings.

Patients \& Methods:

After obtaining approval of the protocol from the regional ethical committee, 3 x 15 adult patients, scheduled for hand surgery, were included in a randomised, blinded prospective study.

Detailed description: After obtaining approval of the protocol from the regional ethical committee, 3 x 15 adult patients, scheduled for hand surgery, were included in a randomised, blinded prospective study.

In all patients a short axillary plexus catheter is positioned close to the median nerve using nerve stimulator.

Technique 1 = 40 ml in catheter Technique 2 = 30 ml behind and 10 ml in front of the brachial artery (BA) Technique 3 = 20 ml behind, 10ml in front of the BA and 10 ml in catheter

Clinical High Field MRI (3T) scanner has simplified the recognition of brachial plexus nerves in the axilla. After injection of local anaesthetic (LA), the identification of the nerve structures is nevertheless difficult. When all nerves are surrounded of LA in the axilla (MRI), it seems to be associated with a clinical complete brachial plexus block

Eligibility criteria: Inclusion Criteria:

* patients scheduled for hand surgery
* ASA 1 - 2
* Weight from 50 - 95 kg
* MR compatible, suitable

Exclusion Criteria:

* Neurologic deficit
* Reaction to LA

Primary outcomes:
measure: Clinical efficacy of the blocks used compared with MRI findings
timeFrame: One year
Secondary outcomes:
Other outcomes:
Locations:
city: Oslo
country: Norway
facility: The Intervention Centre, Rikshospitalet, Oslo University Hospital
Study officials:
affiliation: Diakonhjemmet Sykehus, University of Oslo
name: Trygve TK Kjelstrup, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Rikshospitalet, Dep. of Anesthesiology, Oslo University Hospital
name: Øivind ØK Klaastad, PhD, MD
role: STUDY_DIRECTOR
References:
citation: Kjelstrup T, Hol PK, Courivaud F, Smith HJ, Rokkum M, Klaastad O. MRI of axillary brachial plexus blocks: a randomised controlled study. Eur J Anaesthesiol. 2014 Nov;31(11):611-9. doi: 10.1097/EJA.0000000000000122.