Clinical trial NCT05622045: Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)
Official title: Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Obesity
Body Weight Changes
Keywords: artificial intelligence
obesity
weight loss
Lead sponsor: Loma Linda University
Sponsor class: OTHER
Collaborators: name: Scaled Insights
First posted: 2022-11-18
Enrollment: 59
Sex: ALL
Minimum age (years): 18
Maximum age (years): 74
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Hispanic men and women, 18 to 74 years of age, with obesity, residing in Southern California, who are taking part in the LCSS-Latino Crossover Semaglutide Study.

Brief summary: The goal of this observational study is to learn about the personality attributes and values of people living with obesity that are part of the Latino community, and how these personality attributes and values can help to predict success during a weight loss program.

The main questions it aims to answer are:

* What are the personality attributes and values of people living with obesity that sign up to the LCSS-Latino Crossover Semaglutide Study trial?
* Can behavioral artificial intelligence (a computer formula) predict which patients will complete the LCSS-Latino Crossover Semaglutide Study trial?
* How do behavioral artificial Intelligence predictions (a computer formula) compare to clinician predictions of patient success?
* Can behavioral artificial intelligence (a computer formula) predict patient weight loss, calorie consumption and physical activity levels during the LCSS-Latino Crossover Semaglutide Study trial? Participants will be recorded in English and Spanish while responding to a question regarding participation in a weight loss study.


Eligibility criteria: Inclusion Criteria:

* Participation in the LCSS-Latino Crossover Semaglutide Study

Exclusion Criteria:

* Not a participant of the LCSS-Latino Crossover Semaglutide Study at the point of data collection

Primary outcomes:
measure: Predicted patient weight change success
timeFrame: The voice data measurement will take place at baseline and take about 10-15 minutes for collection to take place.
measure: Clinician predictions
timeFrame: The clinician judgement will be measured during the second month of the subject's weight loss study.
measure: Predicated patient calorie intake
timeFrame: The voice data measurement will take place during the subject's initial clinic visit and take about 10-15 minutes for collection to take place.
measure: Predicated patient physical activity level
timeFrame: The voice data measurement will take at baseline and take about 10-15 minutes for collection to take place.
Secondary outcomes:
measure: Personality attributes and values
timeFrame: The voice data measurement will take place at baseline and take about 10-15 minutes for collection to take place.
measure: Predicted patient attrition rate
timeFrame: The voice data measurement will take place at baseline and take about 10-15 minutes for collection to take place.
Other outcomes:
Locations:
city: Loma Linda
country: United States
facility: Nutrition Research Center, School of Public Health, Loma Linda University
state: California
Study officials:
affiliation: Loma Linda University
name: Celine Heskey, DrPH
role: PRINCIPAL_INVESTIGATOR
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citation: Puhl RM, Phelan SM, Nadglowski J, Kyle TK. Overcoming Weight Bias in the Management of Patients With Diabetes and Obesity. Clin Diabetes. 2016 Jan;34(1):44-50. doi: 10.2337/diaclin.34.1.44. No abstract available.
citation: Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, Wharton S, Yokote K, Zeuthen N, Kushner RF; STEP 1 Study Group. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183. Epub 2021 Feb 10.