Clinical trial NCT06630819: Buccal Infiltration of Different Volumes of Articaine for Extraction.
Official title: Comparing the Effectiveness of Buccal Infiltration of Different Volumes of Articaine for Extraction of Mandibular Posterior Teeth- A Randomized Clinical Trial.
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Buccal Infiltration
Articaine
Anesthesia
Keywords: Buccal infiltration
Articaine
Lead sponsor: Qassim University
Sponsor class: OTHER
First posted: 2024-10-08
Enrollment: 114
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study compares the effectiveness of two different volumes of buccal infiltration of Articaine for the extraction of mandibular posterior teeth. One group receives buccal infiltration of 1.8 ml of 4% Articaine and the other group receives buccal infiltration of 3.6 ml of 4% Articaine.

Detailed description: The most widely and commonly used injection method for the extraction of mandibular posterior teeth is the inferior alveolar nerve block (IANB) technique. However, various complications like pain during injection, transient facial nerve paralysis, trismus, hematoma, and paresthesia are associated with the inferior alveolar nerve block technique.

Local infiltration technique has been proven as a safer and less painful anesthetic injection technique compared to IANB. Unfortunately, the dense nature of cortical bone in the mandibular posterior region hinders sufficient diffusion of anesthetic solution during infiltration. Thus, to achieve an adequate anesthesia for a painless dental extraction of mandibular posterior teeth by infiltration technique, a strong and effective local anesthetic agent having a deeper penetrating property should be used.

Articaine is one of the most widely used local anesthetic agents. It is more potent and has shown more success rate than Lidocaine and Mepivacaine in providing anesthesia in mandibular and maxillary posterior teeth by buccal infiltration diffusibility.

This study compares the effectiveness of two different volumes of buccal infiltration of Articaine for the extraction of mandibular posterior teeth.

Eligibility criteria: Inclusion Criteria:

* All healthy patients (ASA I) or patients with mild systemic disease with no functional limitations (ASA II)
* Patients aged ≥ 18 years of age.
* Patients requiring extraction of mandibular posterior teeth including grossly decayed tooth, grade I mobile tooth, root stumps and indicated for therapeutic reasons.
* Patients not allergic to the drugs or anesthetic agents used in the surgery.

Exclusion Criteria:

* Acute infection at the extraction site.
* Patients indicated for surgical extraction of teeth.
* Patients already taking medications affecting pain assessment.
* Pregnant patients.

Primary outcomes:
measure: Intensity of pain
timeFrame: From reflection of mucoperiosteum till delivery of tooth out of socket.
measure: Time of onset of anesthesia
timeFrame: upto 10 minutes
measure: Presence or absence of pain
timeFrame: From reflection of mucoperiosteum till delivery of tooth out of socket.
Secondary outcomes:
Other outcomes:
Locations:
city: Buraidah
country: Saudi Arabia
facility: Qassim University
state: Al qassim
city: Buraidah
country: Saudi Arabia
facility: College of Dentistry, Qassim University
Study officials:
References: