Clinical trial NCT05779618: Prevalence of Tongue Anomalies in Egyptian Children
Official title: Prevalence of Tongue Anomalies Among Group of Egyptian Children: a Cross-sectional Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Tongue; Anomaly
Keywords: Tongue anomalies
ankyloglossia
Fissured tongue
Geographic tongue
macroglossia
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2023-03-22
Enrollment: 250
Sex: ALL
Minimum age (years): 6
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: school children between six to twelve years old

Brief summary: The purpose of the study is to determine the prevalence of tongue anomalies in a group of Egyptian children and to relate the presence of malocclusion in cases of macroglossia, tongue tie and microglossia.

Detailed description: The tongue is an important and accessible muscle in the oral cavity, it has many functions which includes speech, chewing, swallowing, sucking, control of breathing, growth and developments of the jaws and perception to pain.

Also, many systemic disorders and diseases affect the tongue which makes it a great reflector of the general health.

Tongue anomalies has different frequencies and prevalence between different countries, these differences may be due to geographic, ethnic, gender and age variability, for example a study in Iran in 2003 found that the prevalence of tongue anomalies 34.3%, while another study in Colombia in 2013 found that the prevalence of tongue anomalies on their study population was 79.9%.

The knowledge of the prevalence of tongue anomalies among Egyptian children is missing in the literature which could compromise the quality of dental care, increase the occurrence of orthodontic problems and decrease the chances of early detection of some systemic diseases, since tongue anomalies could help in early determination of some systemic diseases in cases of fissured tongue and geographic tongue as well as early prevention and early intervention of malocclusions and speech defects that might be caused in cases of microglossia, macroglossia and ankyloglossia.

Hence, the knowledge of prevalence of tongue anomalies among Egyptian children can aid in setting a reference which will then help in public health planning and prevention policies.

Eligibility criteria: Inclusion Criteria:

* Participants' age between 6-12 years.
* Co-operative child
* Positive participants' acceptance for participation in the study.
* Participants having responsible care giver answered by approval on the previously sent informed consent which describes the aim \& importance of the study

Exclusion Criteria:

* Patients with history of significant medical conditions
* Participants undertaken anti-fungal drugs in the previous 12 months

Primary outcomes:
measure: prevalence of tongue anomalies
timeFrame: 1 month
Secondary outcomes:
measure: macroglossia, microglossia and ankyloglossia effect on occlusion
timeFrame: 1 month
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Aley Ibn Abi Taleb primary school
city: Cairo
country: Egypt
facility: Mansheyet Gebril primary school
Study officials:
affiliation: Cairo University
name: Randa Abd Al Gawad, Dental PhD
role: STUDY_DIRECTOR
affiliation: Cairo University
name: Yasmin Yousry, Dental PhD
role: STUDY_CHAIR
References:
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citation: Belmehdi A, Harti KE, Wady WE. Ankyloglossia as an oral functional problem and its surgical management. Dent Med Probl. 2018 Apr-Jun;55(2):213-216. doi: 10.17219/dmp/85708.
citation: Avcu N, Kanli A. The prevalence of tongue lesions in 5150 Turkish dental outpatients. Oral Dis. 2003 Jul;9(4):188-95. doi: 10.1034/j.1601-0825.2003.02933.x.
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citation: Rezaei F, Safarzadeh M, Mozafari H, Tavakoli P. Prevalence of Geographic tongue and Related Predisposing Factors in 7-18 Year-Old Students in Kermanshah, Iran 2014. Glob J Health Sci. 2015 Feb 24;7(5):91-5. doi: 10.5539/gjhs.v7n5p91.