Clinical trial NCT06509854: PAthwAy of Dyspneic patIent in Emergency in France
Official title: PAthwAy of Dyspneic patIent in Emergency in France
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Acute Dyspnea
Lead sponsor: Central Hospital, Nancy, France
Sponsor class: OTHER
First posted: 2024-07-19
Enrollment: 89700
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult patients treated in the emergency department for acute dyspnea.

Brief summary: This observational retrospective multi-center study focuses on patients treated for acute dyspnea by emergency medical teams. The primary objective is to identify factors associated with the risk of mortality and rehospitalization in these patients. This evaluation will be conducted both overall and within specific subgroups of interest, including gender (men/women), age categories, mode of admission, and comorbidities.


Eligibility criteria: Inclusion Criteria:

* Man or women aged 18 years and older.
* Patients with acute dyspnea managed by a medical emergency team at the investigator centers between 2010 and 2021.

Exclusion Criteria:

- Cardiorespiratory arrest before emergency department management.

Primary outcomes:
measure: All-cause post-hospitalization mortality and rehospitalization
timeFrame: Within 5 years following hospital discharge
Secondary outcomes:
measure: Proportion of readmissions (all-cause and specific - including hospitalization for acute dyspnea ).
timeFrame: 1 month and 1 year post admission for acute dyspnea in the emergency department
measure: Post admission mortality
timeFrame: Within 20 years following hospital discharge
measure: Post admission rehospitalization
timeFrame: Within 20 years following hospital discharge
measure: Erroneous etiological diagnosis of dyspnea in the emergency department
timeFrame: Within hospital stay, maximum 21 days
measure: All-cause mortality and specific mortality (cardiovascular and non-cardiovascular).
timeFrame: Within 5 years following hospital discharge
measure: Emergency post-admission mortality
timeFrame: Within 20 years following hospital discharge
measure: Emergency post-admission rehospitalisation
timeFrame: Within 20 years following hospital discharge
measure: Duration of stay in the emergency department
timeFrame: Within hospital stay, maximum 21 days
measure: Erroneous etiological diagnosis of dyspnea in the emergency department
timeFrame: Within hospital stay, maximum 21 days
measure: In-hospital mortality
timeFrame: Within hospital stay, maximum 21 days
measure: Length of hospital stay
timeFrame: Within hospital stay, maximum 21 days
measure: Post emergency admission (For dyspnea) mortality and rehospitalization
timeFrame: Within 5 years following hospital discharge
Other outcomes:
Locations:
city: Besançon
country: France
facility: CHU de Besançon
city: Dijon
country: France
facility: CHU de Dijon
city: Lyon
country: France
facility: Hospices civils de Lyon, Groupement Hospitalier Édouard-Herriot
city: Nancy
country: France
facility: CHRU of Nancy
Study officials:
affiliation: Central Hospital, Nancy, France
name: Tahar CHOUIHED, MD, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: CHRU de Nancy
name: Nicolas GIRERD, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: