Clinical trial NCT04541745: Functional Recovery Following Orthopedic Wrist Surgery Under Peripheral Nerve Block Versus General Anesthesia
Official title: Prospective Cohort Study Comparing Functional Recovery Following Orthopedic Wrist Surgery Under Peripheral Nerve Block Versus General Anesthesia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Recovery of Function
Keywords: Upper limb surgery
Functional recovery
Postoperative recovery
General anesthesia
Brachial plexus
Nerve block
Regional anesthesia
Peripheral anesthesia
Lead sponsor: Université de Sherbrooke
Sponsor class: OTHER
First posted: 2020-09-09
Enrollment: 72
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The patient cohort will be composed of all patients undergoing orthopedic wrist surgery under locoregional or general anesthesia at the CIUSSS de l'Estrie-CHUS who meet the selection criteria.

Brief summary: This study aims at determining if there is an association between locoregional anesthesia and postoperative functional recovery for orthopedic surgery to repair a distal radial fracture, as compared to general anesthesia.

Detailed description: All patients undergoing orthopedic wrist surgery under locoregional or general anesthesia at the CIUSSS de l'Estrie-CHUS who meet the selection criteria will be approach to participate in this prospective single-center observational study. Using the visual analog scale and anesthesia scale, the pain and the satisfaction of the patient will be evaluated respectively 2 weeks postoperatively. At the second visit, 6 to 8 weeks postoperatively, the participant will complete the QuickDASH questionnaire to evaluate his functional recovery and the participant's pain will be reassessed with the visual analogue scale. Finally, 12 weeks postoperatively, the wrist-joint range of motion and grip-strength test results will be recorded. The participant will also be asked to complete the QuickDASH and PRWE (Patient-Rated Wrist Evaluation) questionnaires to reevaluate his functional recovery.

Eligibility criteria: Inclusion Criteria:

* 18 years old and more
* American Society of Anesthesiologists (ASA) score I, II, or III
* Single distal radial fracture with or without ulna involvement
* Orthopedic surgery by open reduction of the wrist for a distal radial fracture with or without ulnar involvement

Exclusion Criteria:

* Active pregnancy
* Surgery with combined anesthesia (locoregional and general)
* Locoregional anesthesia with catheter insertion for postoperative analgesia
* Individuals with chronic pain as defined by preexisting neuropathy of the operated arm, preexisting radiculopathy of the operated limb, complex regional pain syndrome, or fibromyalgia
* Polytrauma
* Inability to consent

Primary outcomes:
measure: Functional recovery using the QuickDASH (Quick Disabilities of Arm, Shoulder and Hand) questionnaire
timeFrame: 12 weeks post-surgery
measure: Functional recovery using the PRWE (Patient Rated Wrist Evaluation) Questionnaire
timeFrame: 12 weeks post-surgery
measure: Functional recovery using the range of motion of all movement of the wrist
timeFrame: 12 weeks post-surgery
measure: Functional recovery using the grip strenght
timeFrame: 12 weeks post-surgery
Secondary outcomes:
measure: Pain- 2 weeks
timeFrame: 2 weeks post-operative
measure: Pain - 6 weeks
timeFrame: 6 weeks post-operative
measure: Functional recovery at 6 weeks
timeFrame: 6 weeks post-operative
measure: Patient satisfaction
timeFrame: 2 weeks post-operative
Other outcomes:
Locations:
city: Sherbrooke
country: Canada
facility: CIUSSS de l'estrie- CHUS
state: Quebec
Study officials:
affiliation: Université de Sherbooke
name: Frédérick D'Aragon
role: STUDY_DIRECTOR
References: