Clinical trial NCT06264245: Users of Remote Conferencing and Compression of Sound Dynamics : Auditory Effects
Official title: Users of Remote Conferencing and Compression of Sound Dynamics : Auditory Effects
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Auditory Perception
Lead sponsor: Institut Pasteur
Sponsor class: INDUSTRY
Collaborators: name: Institut de l'Audition
First posted: 2024-02-16
Enrollment: 200
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Subjects with sustained exposure to compressed sounds, as defined by professional participation in broadcast platform events using sound signal processing systems, over the last 3 years, Or Subjects with moderate or limited exposure to compressed and manipulated sound, equivalent to that of a student taking distance-learning courses on a videoconferencing platform, alternating with other face-to-face courses, with the possibility of pauses in listening, exposed for a maximum of 2 years.

Brief summary: The COMPRESSED project is a descriptive, bi-centric and non-invasive study carried out by the CERIAH - IDA - Institut Pasteur and the Haute École Léonard de Vinci in Brussels on volunteer participants identified in two groups :

* be subject to high exposure to compressed sound, as defined by professional participation in events on broadcast platforms using sound signal processing systems, over the last 3 years,
* be subject to moderate or limited exposure to compressed and manipulated sound, equivalent to that of a student following certain distance learning courses. on a videoconferencing platform, alternating with other face-to-face courses, with the ability to listen during breaks, which have been taught for a maximum of 2 years.

The main objective of the COMPRESSED study is to evaluate the auditory effects of exposure to manipulated sounds (compression, filtering, equalisation, accentuation, etc.) from sound distribution platforms on the auditory system of participants who are regularly exposed to these sounds as a result of their professional activity.


Eligibility criteria: Inclusion Criteria:

For all participants:

* Age 18 or over,
* Work with platforms using sound signal processing systems,
* Fluent in English,
* Fluent in French,
* Declare that they have no hearing loss.

For participants in the high exposure group:

- Have had a professional activity over the last three years using broadcasting platforms with sound signal processing systems,

For participants in the moderate or limited exposure group:

- Have worked between one semester and two years with platforms using sound signal processing systems.

Exclusion Criteria:

* Conductive or mixed hearing loss, i.e. where the hearing loss affects both the outer and/or middle ear and the inner ear.
* Have an asymmetric hearing loss, i.e. a difference in average hearing loss between the left and right ear of more than 20 dB,
* Have a history of otitis and/or an ENT disease that permanently affects hearing (vestibular schwannoma, Ménière's disease, sudden or fluctuating deafness, congenital hypoacusis),
* Not fluent in English
* Be under guardianship,
* Deprived of liberty by judicial or administrative decision, or subject to legal protection.

Primary outcomes:
measure: Hearing assessments of participants exposed to manipulated sounds after and before exposure
timeFrame: 2 weeks
Secondary outcomes:
measure: Audiometric thresholds in pure tone from 125 to 8000 Hz in the subject's exposed ear before and approximately one hour after exposure,
timeFrame: 2 weeks
measure: Difference between the threshold of the protective reflex of the auditory pathways (middle ear muscles) measured by impedancemetry in the exposed ear when a contralateral noise is presented for a few seconds.
timeFrame: 2 weeks
measure: Levels of otoemissions in acoustic distortion products in the exposed ear in response to pure tone sound stimuli
timeFrame: 2 weeks
measure: Tinnitus or auditory distortion (hyperacusis) reported by participants before and after exposure.
timeFrame: 2 weeks
measure: Effectiveness of the protective auditory reflexes (or acoustic reflexes), obtained by impedancemetry and derived from the reading of the otoemissions for each participant.
timeFrame: 2 weeks
Other outcomes:
Locations:
city: Bruxelles
country: Belgium
facility: Haute Ecole Léonard De Vinci
city: Paris
country: France
facility: CEntre de Recherche et d'Innovation en Audiologie Humaine
Study officials:
affiliation: CERIAH
name: Paul Avan, MD
role: PRINCIPAL_INVESTIGATOR
References: