Clinical trial NCT05266170: The Effect of EX1 Training in Normal Adults
Official title: The Effect of EX1 Training on Muscle Activity, Heart Rate, and Respiratory Metabolic Energy Consumption Rate in Normal Adults
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Aerobic Exercises
Anaerobic Exercises
Lead sponsor: Samsung Medical Center
Sponsor class: OTHER
First posted: 2022-03-04
Enrollment: 40
Sex: ALL
Minimum age (years): 19
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Normal adults aged 19 to 65 years

Brief summary: In this study, when performing aerobic and anaerobic exercise with EX1 applied to normal adults between the ages of 19 and 65. The purpose of this study was to determine the effect on the muscle activity of the trunk and lower extremities compared with and without EX1.

Detailed description: In this study, aerobic exercise and anaerobic exercise for normal adults were divided into two visits for a total. For aerobic exercise, the investigators compared the aerobic treadmill walking program without EX1 \[30 minutes of moderate (64-76% HRmax, 12-14 of RPE) aerobic treadmill walking, 40 minutes including warm-up and cool-down times\], the aerobic treadmill walking program with EX1 \[30 minutes of moderate (64-76% HRmax, 12-14 of RPE) aerobic treadmill walking, 40 minutes including warm-up and cool-down times\] , and the high-intensity interval exercise (HIIT) program with EX1 \[High-intensity-low-intensity interval walking exercise was performed at treadmill speed (High: 90-95% HRmax, 15-17 of RPE/Low: 60-70% HRmax, 9-11 of RPE) and EX1 resistance strength (High: resistance intensity 7- 9/Low: Resistance strength 0-2)\] to check the effect on muscle activity, heart rate, and respiratory metabolic energy consumption rate.

Eligibility criteria: Inclusion Criteria:

* Healthy adults aged 19 to 65 years without a history of central nervous system disease

Exclusion Criteria:

* Those who have difficulty walking independently due to problems such as visual field defects or fractures
* Those who have difficulty understanding the exercise program due to severe cognitive decline (Korean-Mini-Mental State Examination, K-MMSE≤10)
* Those who have difficulty participating in exercise programs due to adult diseases such as uncontrolled hypertension and diabetes
* Those who are at risk of falling while walking due to severe dizziness
* Those who are less than 140 cm or more than 185 cm in height that is not suitable size for the wearing of the walking assistance robot
* Those who are overweight based on body mass index (BMI) 35 or higher

Primary outcomes:
measure: Reduction on muscle activity (%MVC)
timeFrame: 3hours/2hours
Secondary outcomes:
measure: Reduction on metabolic energy expenditure (ml·kg-1·min-1)
timeFrame: 3hours
measure: Reduction on heart rate (beats per minute, bpm)
timeFrame: 3hours
measure: Distinction on muscle activity (%MVC)
timeFrame: 3hours
measure: Distinction on metabolic energy expenditure (ml·kg-1·min-1)
timeFrame: 3hours
measure: Distinction on heart rate (beats per minute, bpm)
timeFrame: 3hours
measure: Distinction on muscle activity (%MVC)
timeFrame: 2hours
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center
Study officials:
affiliation: Samsung Medical Center
name: Yun-Hee Kim, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: