Clinical trial NCT05972941: Nicotine and Tobacco Message Framing Among LGBT Young Adults
Official title: The Effect of Nicotine and Tobacco Message Framing on Use Among Diverse Groups of Young Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Tobacco-Related Carcinoma
Keywords: health communication
LGBT
Lead sponsor: Ohio State University Comprehensive Cancer Center
Sponsor class: OTHER
Collaborators: name: National Institutes of Health (NIH)
name: National Cancer Institute (NCI)
First posted: 2023-08-02
Enrollment: 252
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This trial refines and evaluates how cultural targeting influences the effectiveness of anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product (polytobacco use). Polytobacco use is associated with nicotine dependence and tobacco use into adulthood, and is disproportionately high among LGBT young adults. This trial seeks to determine how cultural targeting can be applied to communicate polytobacco use risk to at-risk LGBT young adults.

Detailed description: The goal of this study is to identify if culturally targeted (CT) or non-targeted (NT) anti-polytobacco messages are most effective for engaging LGBT consumers. Using the most effective NT messages from Aim 1, investigators will create a set of CT messages. Message framing will remain consistent between CT and NT messages; however, CT messages will include language and graphics representing LGBT values formative research and the existing peer-reviewed literature. Participants will be randomized to view CT or NT messages in a virtual lab where investigators will assess eye-tracking, self-reported perceived effectiveness, risk perceptions, and behavioral intentions. Participants will also complete a 1-week follow-up. The study aims to determine the effects of cultural targeting on attention to anti-polytobacco messages and perceived effectiveness among LGBT young adults susceptible to polytobacco use.

Eligibility criteria: Inclusion Criteria:

* Speaks English fluently
* Self-identifies as lesbian, gay, bisexual, transgender, queer, or another non- heterosexual orientation or non-binary gender identity
* Ever used e-cigarettes AND combustible cigarettes
* Currently uses e-cigarettes, combustible cigarettes, or both e-cigarettes and combustible cigarettes
* Resides in the United States
* Access to a laptop or desktop computer with a camera for virtual eye-tracking

Exclusion Criteria:

* Glaucoma
* Cataracts

Primary outcomes:
measure: Visual Attention - Dwell Time
timeFrame: During intervention on Day 1, on average 3 minutes
measure: Visual Attention - Time to First Fixation
timeFrame: During intervention on Day 1, on average 3 minutes.
measure: Perceived Message Effectiveness - Message Perceptions
timeFrame: Immediately post-exposure to intervention
measure: Perceived Message Effectiveness - Effects Perceptions
timeFrame: Immediately post-exposure to intervention
measure: Change in Behavioral Intentions
timeFrame: Change from Baseline in behavioral intentions immediately post-exposure to intervention
measure: Behavioral Intentions: Quitting Smoking
timeFrame: Difference between conditions in behavioral intentions to quit smoking at 1-week follow-up after intervention exposure
measure: Behavioral Intentions to Quit Vaping
timeFrame: Difference between conditions in behavioral intentions to quit vaping at 1-week follow-up after intervention exposure
Secondary outcomes:
measure: Reactance
timeFrame: Immediately post-exposure to intervention
measure: Ad Relevance
timeFrame: Immediately post-exposure to intervention
measure: Liking
timeFrame: Immediately post-exposure to intervention
measure: Attitudes
timeFrame: Immediately post-exposure to intervention
measure: Response Efficacy
timeFrame: Immediately post-exposure to intervention
measure: Qualitative Recall of Health Messages
timeFrame: 1-week follow-up after intervention exposure
Other outcomes:
Locations:
city: Columbus
country: United States
facility: The Ohio State University
state: Ohio
Study officials:
affiliation: The Ohio State University College of Public Health
name: Joanne G Patterson, PhD
role: PRINCIPAL_INVESTIGATOR
References: