louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT05457777: The Effect of Motivational Interviews on the Digital Game Addiction Levels of Nursing Students
Official title: The Effect of Motivational Interviews Based on Change Stages on the Digital Game Addiction Levels of Nursing Students
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Motivational Interview
Addiction
Keywords: digital game addiction
nursing study
change stages
motivational interview
Lead sponsor: Cumhuriyet University
Sponsor class: OTHER
First posted: 2022-07-14
Enrollment: 72
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Our study has two groups of 36 participants each. Our study is an experimental study with pretest-posttest control group.
Primary purpose: OTHER

Brief summary: The aim of this study is to reveal the effect of motivational interviewing based on change stages on digital game addiction. This study will be conducted with a total of 72 individuals assigned by a randomization site from all nursing students who study at Sivas Cumhuriyet University, Faculty of Health Sciences, voluntarily participated in the study, and were found to be digital game addicts. These individuals will be equally distributed to the intervention and control groups. Personal Information Form, Stages of Change Questionnaire and Digital Game Addiction Scale will be distributed to individuals to answer. The obtained data will be analyzed statistically.

Detailed description: The aim of this study is to reveal the effect of motivational interviewing based on change stages on digital game addiction. This study will be conducted with a total of 72 individuals assigned by a randomization site from all nursing students who study at Sivas Cumhuriyet University, Faculty of Health Sciences, voluntarily participated in the study, and were found to be digital game addicts. These individuals will be equally distributed to the intervention and control groups. Each group will contain 36 participants. the participants in intervention group will take motivational interventions while the individuals who have digital game addiction in control group will not take this application. Personal Information Form, Stages of Change Questionnaire and Digital Game Addiction Scale will be distributed to individuals to answer. The obtained data will be analyzed statistically.

Eligibility criteria: Inclusion Criteria:

Nursing students who:

* agree to participate in the study
* are over 18 years
* have game addiction
* agree to participate in the negotiations

Exclusion Criteria:

Individuals who:

* do not agree to participate in the study

Primary outcomes:
measure: Digital Game Addiction Scale
timeFrame: up to three months
Secondary outcomes:
Other outcomes:
Locations:
city: Sivas
country: Turkey
facility: Sivas Cumhuriyet University
state: Center
city: Sivas
country: Turkey
facility: Sivas Cumhuriyet University
state: Center
Study officials:
affiliation: Cumhuriyet University
name: Semra Zorlu, PhD
role: STUDY_DIRECTOR
References:
Clinical trial NCT05297877: Use of Artificial Intelligence Cardiac Ultrasound Technology in Teaching Point of Care Cardiac Ultrasound
Official title: Use of Artificial Intelligence Cardiac Ultrasound Technology in Teaching Point of Care Cardiac Ultrasound - a Randomised Controlled Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Cardiac
Keywords: Cardiac Ultrasound
Lead sponsor: National University of Singapore
Sponsor class: OTHER
First posted: 2022-03-28
Enrollment: 50
Sex: ALL
Minimum age (years): 19
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The aim of the study is to evaluate the effectiveness of artificial intelligence (A.I.) cardiac ultrasound technology in teaching point of care cardiac ultrasound (POCUS Cardiac).


Eligibility criteria: Inclusion Criteria:

* Medical students with no prior training in point of care cardiac ultrasound

Exclusion Criteria:

* Medical students who have received prior training in point of care cardiac ultrasound
* Participants who are unable to complete the entire training programme (pre-training MCQ, simulation session, post-training MCQ, practical evaluation, follow up practical evaluation one month later)

Primary outcomes:
measure: Effectiveness of artificial intelligence (A.I.) cardiac ultrasound technology in teaching point of care cardiac ultrasound vs conventional echo machine
timeFrame: Study till 1 month post-study
Secondary outcomes:
Other outcomes:
Locations:
city: Singapore
country: Singapore
facility: National University of Singapore
Study officials:
affiliation: National University Health System
name: Suresh Paranjothy
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00870077: A Pilot Study on Whey Protein Supplementation in Non Alcoholic Fatty Liver Disease
Official title: Effect of a Whey Protein Supplementation on Intrahepatic Lipids in Obese Patients With Non-alcoholic Fatty Liver Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Non-alcoholic Fatty Liver Disease
Obesity
Keywords: Intrahepatic fat
obesity
body fat
impaired glucose tolerance
Lead sponsor: University of Lausanne
Sponsor class: OTHER
First posted: 2009-03-26
Enrollment: 11
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: An increase in dietary protein intake has been shown to blunt the increase in intrahepatic fat induced by high fat feeding in healthy individuals. The purpose of this study is to determine if a protein supplementation decreases intrahepatic fat in obese patients with non-alcoholic fatty liver disease.

Detailed description: 12 obese patients will be be treated with a dietary whey protein supplementation over 4 weeks. Their intrahepatic fat content, glucose tolerance, and body weight will be evaluated before and after 4 weeks of supplementation.

Eligibility criteria: Inclusion Criteria:

* BMI higher than 35 kg/m2
* age 18-50 years
* sex male or female
* ASAT/ALAT \> 1.8

Exclusion Criteria:

* treatment with hypolemic or antidiabetic agents
* blood glucose \> 7 mmol/l
* alcohol intake \> 20g/day
* creatinin \> 120 umol/l)
* contra-indications to Magnetic resonnance imaging

Primary outcomes:
measure: intrahepatic fat
timeFrame: before and after 4 weeks of whey protein supplementation
Secondary outcomes:
measure: glucose metabolism
timeFrame: 4-hour oral glucose tolerance test with indirect calorimetry
measure: body weight and body fat
timeFrame: before and after 4 weeks whey protein supplementation
Other outcomes:
Locations:
city: Lausanne
country: Switzerland
facility: Centre d'investigations cliniques "cardiomet"/ CHUV
state: VD
Study officials:
affiliation: Centre Hospitalier Universitaire Vaudois
name: Luc Tappy, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bortolotti M, Maiolo E, Corazza M, Van Dijke E, Schneiter P, Boss A, Carrel G, Giusti V, Le KA, Quo Chong DG, Buehler T, Kreis R, Boesch C, Tappy L. Effects of a whey protein supplementation on intrahepatocellular lipids in obese female patients. Clin Nutr. 2011 Aug;30(4):494-8. doi: 10.1016/j.clnu.2011.01.006. Epub 2011 Feb 1.
Clinical trial NCT02186977: Proof Of Concept : Immunogenicity and Safety of hepB Injection in the Dermis Using VAX-ID
Official title: Proof Of Concept Study: Immunogenicity and Safety of Hepatitis B Injection in the Dermis in Healthy Volunteers Using an Intradermal Injection Device (VAX-ID)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Hepatitis B
Keywords: immunogenicity
safety
proof of concept
Lead sponsor: Novosanis NV
Sponsor class: INDUSTRY
First posted: 2014-07-10
Enrollment: 48
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: A proof of concept (POC) study will be conducted in 44 volunteers that have been fully vaccinated against hepatitis B in the past (at least 5 years ago) to assess the safety and immunogenicity of intradermal vaccination with hepatitis B surface vaccine antigen using a newly developed intradermal injection device VAX-ID, compared to intramuscular and intradermal (Mantoux technique) injection.


Eligibility criteria: Inclusion Criteria:

* healthy adults, checked anamnestically (based on medical history) at entry of the study
* 18-35 years
* vaccination status: fully vaccinated against hepatitis B at least 5 years ago, with proof of vaccine response (to avoid non-response among the subjects). Subjects has to ask for a document of this proof at the service occupational medicine of the University of Antwerp.
* capable of understanding, reading and writing Dutch

Exclusion Criteria:

* other vaccination(s) 4 weeks before study onset
* pregnancy and lactation (women will be questioned during anamnesis)
* plan to have other vaccination during the study period

Primary outcomes:
measure: Anamnestic response after intradermal or intramuscular hepatitis B booster vaccination in previously fully immunized subjects
timeFrame: after 14 days
Secondary outcomes:
measure: Safety: solicited local and systemic reactions, unsolicited adverse events and Serious Adverse Events occurrence, intensity and relationship to vaccination of all Adverse Events reported during the 14-day follow-up period after the challenge dose
timeFrame: during 14 days post vaccination
Other outcomes:
Locations:
city: Wilrijk
country: Belgium
facility: Centre for the Evaluation of Vaccination Vaccine & Infectious Disease Institute
state: Antwerp
Study officials:
affiliation: Centre for the Evaluation of Vaccination Vaccine & Infectious Disease Institute
name: Pierre Van Damme, Prof
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05646277: Patient Reported Experience Measures Following a First Remote Orthodontic Consultation : a Randomized Controlled Trial
Official title: Patient and Practitionners Reported Experience Measures (PREMs) Following a First Remote Orthodontic Consultation Versus a First Face-to-face Orthodontic Consultation
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Odontologic Disorders
Keywords: remote-assisted teleconsultation
Lead sponsor: Centre Hospitalier Universitaire de Nice
Sponsor class: OTHER
First posted: 2022-12-12
Enrollment: 60
Sex: ALL
Minimum age (years): 6
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients requesting a first orthodontic consultation in the Orthodontics Unit (Odontology, Hospital of Nice)

Brief summary: The objective of this present randomized controlled trial was to investigate patient's and practitioner's Reported Outcomes Measures (PROMs) following a first standard face-to-face consultation versus a first orthodontic teleconsultation (video-assisted remote orthodontic consultation).


Eligibility criteria: Inclusion criteria :

- Patients requesting a first orthodontic consultation.

Exclusion criteria :

- children not accompanied by their legal guardian (under 18 years old).

Primary outcomes:
measure: Overall patient satisfaction between first remote-assisted orthodontic teleconsultation and classic first consultation
timeFrame: 8 months
Secondary outcomes:
measure: Overall practionner satisfaction between first remote-assisted orthodontic teleconsultation and classic first consultation
timeFrame: 8 months
Other outcomes:
Locations:
city: Nice
country: France
facility: CHU de NICE
Study officials:
References:
Clinical trial NCT00456677: Evaluation of the Utility of Minocycline as an Anti-Inflammatory Agent in the Treatment of Asthma
Official title: Evaluation of the Utility of Minocycline as an Anti-Inflammatory Agent in the Treatment of Asthma
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Asthma
Keywords: minocycline
asthma
oral corticosteroids
Lead sponsor: State University of New York - Downstate Medical Center
Sponsor class: OTHER
First posted: 2007-04-05
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Double blind, placebo-controlled. crossover study
Primary purpose: TREATMENT

Brief summary: Trial of effects of minocycline as "add-on" therapy to adults with asthma with a history of requiring at least one episode of oral steroid therapy to control the disease.

Detailed description: This is a double-blind, placebo-controlled crossover study of adult asthmatics given minocycline 150 mg po BID or placebo as add-on therapy for eight weeks each. Each eight week arm is separated by a four week wash-out. Spirometry is performed at the baseline and end of each arm. Daily symptoms scores, peak flow rates, and oral steroid requirements are recorded. A standardized asthma quality of life symptoms assessment is made every four weeks (AQLQ, Juniper).

Eligibility criteria: Inclusion Criteria:

* Adult asthmatics
* History of or current use of oral steroids to control symptoms

Exclusion Criteria:

* Pregnant women

Primary outcomes:
measure: Decrease in oral steroid therapy requirements.
timeFrame: 8 weeks
Secondary outcomes:
measure: improvement in symptoms scores
timeFrame: 8 weeks
measure: improvement in spriometric parameters
timeFrame: 8 weeks
measure: improvement in morning and evening peak flow
timeFrame: 8 weeks
measure: decrease in rescue inhaler usage
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Brooklyn
country: United States
facility: SUNY Downstate Medical Center
state: New York
Study officials:
affiliation: State University of New York - Downstate Medical Center
name: Rauno Joks, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06601777: Evaluation of the Effectiveness, Safety, and Cost of a Smart Hospital System for Patients With Chronic Obstructive Pulmonary Disease
Official title: Evaluation of the Effectiveness, Safety, and Cost of a Smart Hospital System for Patients With Chronic Obstructive Pulmonary Disease: Prospective Multicenter Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: COPD
Lead sponsor: Yonsei University
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 198
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This study aims to analyze the effectiveness/safety/cost of the Smart Homespital system that provides a service that allows patients with Chronic Obstructive Pulmonary Disease to easily access and use biosignals generated using biosignal collection medical equipment at home.


Eligibility criteria: Inclusion Criteria:

Patients diagnosed with COPD who meet the following pulmonary function test results:

1. Pre FEV1 \< 80% \*\*or\*\*
2. Pre FVC \< 80% \*\*or\*\*
3. DLCO \< 60%

Exclusion Criteria:

1. Patients who do not agree to participate in the study.
2. Patients who fail to use the medical device equipment.
3. Patients where tracking during the study period is expected to be impossible.
4. Patients who have difficulty communicating verbally.
5. Patients who are bedridden or unable to exercise at all due to severe cardiorespiratory dysfunction.
6. Patients receiving hospital-centered rehabilitation treatment during the study period.

Primary outcomes:
measure: Respiratory symptom questionnaire
timeFrame: After applying the Smart Homespital system(12weaks)
Secondary outcomes:
measure: Depression Questionnaire
timeFrame: Survey every 2 weeks during the 12-week Homespital system application, then at 3, 6, and 9 months after the start of the study.
measure: Service satisfaction evaluation
timeFrame: After 12 weeks of applying the Smart Homespital system.
measure: safety
timeFrame: Measured after the study ends (9 months later).
measure: cost assessment
timeFrame: After study ends (9 months later)
measure: 6 minute walking test
timeFrame: At 3, 6, and 9 months.
measure: pulmonary function test
timeFrame: At 3, 6, and 9 months.
measure: system compliance
timeFrame: During the 12-week period of applying the Homespital system.
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Severance Hospital
Study officials:
References:
Clinical trial NCT02810977: Ultrasound Assessment of Gastric Content and Volume
Official title: Ultrasound Assessment of Gastric Content and Volume After Complete Fasting in Patients Undergoing Surgery at Two University Hospitals: A Multicentric Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Fasting
Keywords: gastric volume
gastric content
ultrasound
perioperative fasting
Lead sponsor: Fundación Santa Fe de Bogota
Sponsor class: OTHER
Collaborators: name: Hospital Universitario San Ignacio
First posted: 2016-06-23
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Men and women 18 years or older requiring surgery with complete preoperative fasting (more than 8 hours but less than 14), ASA I-III.

Brief summary: Anesthesiologists try to avoid complications with significant peri -operative morbidity and mortality such as bronchoaspiration in patients requiring a surgical procedure under anesthesia. Currently, this is achieved based on experts recommendations from the American Society of Anesthesiologists. However, there are tools like ultrasound that allow assessment of gastric content and volume. This tool allows to individualize each patient and base the decisions objectively. The investigators will assess gastric content and volume by ultrasound in patients who have fasted and require surgery at two University Hospitals.


Eligibility criteria: Inclusion Criteria:

* Adults ≥ 18 years
* perioperative fasting time between 8 and 14 hours
* American Society of Anesthesiologists status I, II, III
* Scheduled surgery

Exclusion Criteria:

* Abdominal pathology surgical emergency
* Unable to adopt right lateral decubitus position
* Altered gastrointestinal tract anatomy excluding hiatal hernia
* Body mass index greater than 40
* Patients on enteral nutrition probe or with nasogastric probe
* Pregnancy

Primary outcomes:
measure: Gastric content
timeFrame: June to December
measure: Gastric volume
timeFrame: June to December
Secondary outcomes:
measure: Association of gastric content and volume with special conditions as assessed by Anova or Kruskal as appropriate
timeFrame: June to December
measure: Association with fasting time
timeFrame: June to December
Other outcomes:
Locations:
city: Bogota
country: Colombia
facility: Hospital Universitario Fundacion SantaFe de Bogota
city: Bogota
country: Colombia
facility: Hospital Universitario San Ignacio
Study officials:
affiliation: Fundacion Santa Fe de Bogota
name: Jose A Valencia, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04577677: Understanding the Neural Mechanisms Behind tDCS
Official title: Understanding the Neural Mechanisms Behind Transcranial Direct Current Stimulation
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: tDCS Mechanisms
Lead sponsor: KU Leuven
Sponsor class: OTHER
First posted: 2020-10-08
Enrollment: 130
Sex: ALL
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: OTHER

Brief summary: The aim of the study is to investigate the neural mechanisms underpinning transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique in which a direct current is passed through scalp electrodes. A series of experiments will be conducted to understand and characterize the transcranial and transcutaneous mechanisms of tDCS. To investigate this research question, every participant will undergo three stimulation conditions (active, sham and control). In the control condition, an anaesthetic cream will be applied to anaesthetize the nerves in the scalp. In addition, the effectiveness of tDCS and peripheral nerve stimulation will be compared. Ultimately, the obtained knowledge can lead to the development of improved non-invasive neuromodulation therapies, which can lead to more effective treatments of a variety of neurological and psychiatric disorders.


Eligibility criteria: Inclusion Criteria:

* good general health

Exclusion Criteria:

* Epilepsy or family history of epilepsy
* Migraine
* Allergic to lidocaine or benzocaine
* Pregnant
* History of or currently suffering from:
* neurological diseases
* psychiatric diseases, depression or anxiety (Annex B and Annex C)
* History of:
* brain surgery
* brain thrombosis
* cerebral hemorrhage
* severe head trauma
* meningitis
* long period of loss of consciousness (\> 1 hour)
* Metal parts in the head or upper body:
* Defibrillator, implanted medication pump
* Metal prosthesis in ear, hart, ...
* Deep brain stimulator
* Coronary bypass or intracranial or aneurysm clips (brain arteries, aorta, etc.)

Primary outcomes:
measure: Visual Analogue Scale
timeFrame: 30 minutes during stimulation
measure: Reaction time
timeFrame: 20 minutes during tDCS stimulation
measure: Reaction time
timeFrame: 20 minutes during peripheral nerve stimulation
measure: Amplitudes of event related potentials
timeFrame: during tDCS
measure: Amplitudes of event related potentials
timeFrame: during peripheral nerve stimulation
measure: Pupil dilations
timeFrame: during peripheral nerve stimulation
Secondary outcomes:
Other outcomes:
Locations:
city: Leuven
country: Belgium
facility: KULeuven
state: Vlaams-Brabant
Study officials:
References: