Clinical trial NCT06852118: Using the Adductor Magnus Plain Block As an Innovative Approach for Sciatic Nerve Block for Lower Limb Surgeries.
Official title: Efficacy of Adductor Magnus Muscle Plane Injection for Sciatic Nerve Block Versus Subgluteal Approach in Combination with Femoral Nerve Block in Knee Surgeries- a Randomized Control Study.
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Adductor Magnus Plain Injection for Sciatic Nerve Block
Keywords: sciatic nerve block
Femoral nerve
Adductor magnus muscle
knee surgeries
Lead sponsor: Al-Azhar University
Sponsor class: OTHER
First posted: 2025-02-28
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: the goal of this clinical trial is to compare the efficacy of adductor magnus muscle plane injection as an approach for sciatic nerve block to sub-gluteal approach in combination with femoral nerve blocks as perioperative analgesia in knee surgeries.


Eligibility criteria: Inclusion Criteria:

* ASA (American Society of Anaesthesiologists) Physical Status I-III.
* Patients who consent to receive regional anesthesia.

Exclusion Criteria:

* Patients with a history of allergy to local anesthetics.
* Pre-existing neurological deficits in the lower extremities.
* Coagulopathy or anticoagulation therapy that cannot be safely discontinued.
* Infection at the site of block injection.
* Severe obesity (BMI \> 40).
* Patients with contraindications to regional anesthesia.
* peripheral neuropathy.
* Psychiatric disorders and communication difficulties.

Primary outcomes:
measure: Assessment of sciatic sensory block
timeFrame: At 30 minutes after the block
measure: Assessment of sciatic motor block
timeFrame: At 30 minutes after the block
Secondary outcomes:
measure: Postoperative pain scores
timeFrame: At 1, 6, 12, and 24 hours post-operative
measure: The onset of sciatic sensory blockades
timeFrame: Every 3 minutes with maximum time 30 minutes (if no changes within 30 min the patient will be excluded from the study)
measure: The duration of the sciatic nerve block procedure
timeFrame: during sciatic nerve block conduction
measure: Visibility scores for the sciatic nerve
timeFrame: during sciatic nerve block using sub gluteal approach conduction
measure: Visibility scores for Adductor magnus muscle (AMM)
timeFrame: during sciatic nerve block using adductor magnus muscle plain block conduction
measure: Patient satisfaction
timeFrame: Before the patient discharge
measure: The onset of the Sciatic motor block
timeFrame: Every 3 minutes with maximum time 30 minutes (if no changes within 30 min the patient will be excluded from the study)
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Faculity of medicine - Al-Azhar University hospitals
Study officials:
References:
citation: Ben-David B, Schmalenberger K, Chelly JE. Analgesia after total knee arthroplasty: is continuous sciatic blockade needed in addition to continuous femoral blockade? Anesth Analg. 2004 Mar;98(3):747-9, table of contents. doi: 10.1213/01.ane.0000096186.89230.56.
citation: Shanthanna H, Singh B, Guyatt G. A systematic review and meta-analysis of caudal block as compared to noncaudal regional techniques for inguinal surgeries in children. Biomed Res Int. 2014;2014:890626. doi: 10.1155/2014/890626. Epub 2014 Aug 5.
citation: Wang L, Qu Y, Deng Y, Li J, Liu Y, Wu C. Evaluation of a New Method of Sciatic Nerve Block: A Prospective Pilot Study. J Pain Res. 2023 Jun 16;16:2091-2099. doi: 10.2147/JPR.S404489. eCollection 2023.