Clinical trial NCT03926247: Immigrant Well-being Project: Transdisciplinary Ecological Mental Health Intervention for Mexican Immigrants
Official title: Addressing the Social-Structural Determinants of Mental Health Through Adaptation of a Transdisciplinary Ecological Intervention Model for Mexican Immigrants
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Mental Health
Keywords: pilot study
mental health
immigrant
within-group longitudinal design
Lead sponsor: University of New Mexico
Sponsor class: OTHER
Collaborators: name: National Institutes of Health (NIH)
name: National Institute on Minority Health and Health Disparities (NIMHD)
First posted: 2019-04-24
Enrollment: 56
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: This is a pilot study of an intervention with a within-group longitudinal design. All participants will participate in the intervention.
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The goal of this study is to test a transdisciplinary ecological approach to reducing mental health disparities among Mexican immigrants by adapting and integrating a multilevel community-based advocacy, learning, and social support intervention (Immigrant Well-being Project, IWP) into existing efforts at three community partner organizations that focus on mental health, education, legal, and civil rights issues for Mexican immigrants. This research is innovative and significant because it employs cutting edge strategies to address social-structural determinants of mental health and examines the community-engaged process of adapting and testing the impact of a multilevel intervention originally designed for refugees. The IWP intervention emphasizes a sustainable and replicable partnership model between community-based organizations and universities that involves Mexican immigrants and undergraduate advocates working together to: a) increase immigrants' abilities to navigate their communities; b) improve immigrants' access to community resources; c) enhance meaningful social roles by valuing immigrants' culture, experiences, and knowledge; d) reduce immigrants' social isolation; and e) increase communities' responsiveness to immigrants through changes in policy and practice. The IWP is administered by university students enrolled in a service learning course, and has two elements: 1) Learning Circles, which involve cultural exchange and one-on-one learning opportunities, and; 2) Advocacy, which involves collaborative efforts to mobilize community resources related to health, housing, employment, education, and legal issues. Studies of the intervention model with refugees demonstrated feasibility, appropriateness, acceptability, and evidence that the intervention decreased participants' psychological distress and increased protective factors, and impacted changes in system-wide policies and practices. After completing in-depth ethnographic interviews with 24 Mexican immigrant adults to elucidate their mental health needs, stressors, current political/economic/social context, and local solutions, and a process of community engagement and intervention adaptation, a mixed methods strategy with data collected from 90 participants at four time points over a period of 14 months will be used to test the impact of the 6-month intervention on reducing psychological distress, increasing protective factors (access to resources, English proficiency, environmental mastery, and social support), and achieving system-level changes in organizational, local, and state policies and practices that impact Mexican immigrants' well-being. Mechanisms of intervention effectiveness will be explored by testing mediating relationships between protective factors and psychological distress. Qualitative data will explore feasibility and acceptability of the intervention, participants' experiences in the intervention, and unexpected impacts; document multilevel changes and the context of implementation at each site; and inform interpretation of quantitative data. Quantitative and qualitative data on the quality of the CBPR partnerships and their relationship to multilevel outcomes will also be examined.

Detailed description: The goal of this research is to advance the science of community-level mental health interventions that aim to reduce social inequities and health disparities. The proposed study will adapt and integrate a successfully implemented multilevel, ecological intervention that addresses social-structural determinants of mental health into existing efforts at three community partner organizations that focus on mental health, education, legal, and civil rights issues for Mexican immigrants in New Mexico. Using a mixed methods longitudinal design, the processes and outcomes of the collaborative, community-based intervention efforts, including the impact of the quality of the community-based participatory research (CBPR) partnerships on individual, organizational, and community-level outcomes, will be illuminated.

Social and structural inequities contribute significantly to increasing health disparities globally, with the increasing numbers of migrants throughout the world bearing a disproportionate burden. The immigrant share of the U.S. population has risen steadily over the past four decades, comprising 13.5% of the total population in 2015, with Mexican-born immigrants accounting for 27% of all immigrants. The social, legal, and economic context of the migration process, including increasing uncertainty, discrimination, stigma, lack of access to resources, and fear of deportation and family separation based on immigration policies and public perception of immigrants as a threat all have a critical impact on adverse mental health outcomes among Mexican immigrants in the U.S. In addition, Mexican immigrants have low utilization rates for mental healthcare, in part because of barriers that include lack of health insurance, ineligibility for governmental health programs, discrimination, lack of interpretation services and culturally appropriate care, and an anti-immigrant political and economic climate. Although evidence points to the need to address socio-structural determinants, many mental health interventions offered to Mexican immigrants have focused on individual-level predictors of mental health. Also, Mexican immigrants' health outcomes are often viewed within the Latino health paradox, and therefore are frequently overlooked in mental health research and development of appropriate interventions, despite mounting evidence of mental health disparities and disproportionate exposure to trauma. Thus, multilevel, transdisciplinary intervention approaches that address social-structural determinants of mental health, are culturally appropriate, build upon Mexican immigrants' strengths, are cost-effective and scalable, and occur in non-stigmatized settings are needed.

In prior NIH-funded research, the PI and community partners developed and tested a 6-month community-based advocacy, learning, and social support intervention, which pairs paraprofessional university students with refugee adults to engage in mutual learning and social change efforts. The intervention was found to decrease participants' psychological distress, improve their quality of life, access to resources, social support, and English proficiency, and improve communities' responsiveness to refugees; and also proved to be highly acceptable, cost effective, and sustainable. The objective of this study is to: a) adapt the intervention for Mexican immigrants (Immigrant Wellbeing Project; IWP); b) integrate IWP into existing efforts at three community partner organizations; and c) elucidate new understandings of partnership and intervention processes that lead to sustainable multilevel changes and the reduction of mental health disparities and related social inequities.

Aim 1. Conduct an in-depth study of the mental health needs, stressors, current political/economic/social context, and local solutions as experienced by 24 Mexican recent and non-recent immigrants and their families residing in Bernalillo County New Mexico and contextualized by staff at three community partner organizations.

Aim 2. Building on the data from Aim 1, use a CBPR approach to adapt the intervention model (IWP) and integrate it within existing service delivery and social change efforts at three community partner organizations.

Aim 3. Using a mixed methods longitudinal design, investigate the feasibility and acceptability of the adapted community-based mental health intervention and test the quality of the CBPR partnership and impact of the intervention on mental health problems and protective factors among 90 Mexican immigrants and on organizational and government changes in policies and practices impacting immigrant mental health.

3.1 The IWP and collaborative adaptation/integration process will be feasible and acceptable and will serve as a model for implementing and studying multilevel, community-based intervention efforts.

3.2 IWP participants' psychological distress will decrease significantly over time.

3.3 IWP participants' protective factors (access to resources, English proficiency, environmental mastery, social support) will increase significantly over time.

3.4 Lower levels of psychological distress will be mediated by the protective factors.

3.5 Qualitative data will document changes in organizational and governmental policies and practices and the context of implementation at each site, explore other impacts, and inform interpretation of quantitative data.

3.6 Quality of CBPR partnership at each site will be related to policy/practice changes and health outcomes.

As one of the core research projects of the Transdisciplinary Research, Equity and Engagement Center for Advancing Behavioral Health (TREE), this study will benefit from and contribute to collaborative efforts to elucidate and address the impact of social-structural (e.g., racism, lack of access to resources) and historical (e.g., violence, trauma, colonization) determinants of mental health for immigrant and indigenous populations.

Eligibility criteria: Inclusion Criteria:

* Mexican immigrant
* Residing in Bernalillo County, New Mexico

Exclusion Criteria:

* Severe cognitive functioning problems
* Imminent suicide risk
* Mental illness that is so severe as to impede participation in a group and that warrants immediate individual treatment

Primary outcomes:
measure: Linear Change From Baseline to 14-month Follow-up in Depression/Anxiety Symptom Score Assessed by the Hopkins Symptom Checklist-25
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
measure: Linear Change From Baseline to 14-month Follow-up in PTSD Symptom Score Assessed by the PTSD Symptom Checklist (Civilian Version)
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
measure: Linear Change From Baseline to 14-month Follow-up in Stress Assessed by the Abbreviated Hispanic Stress Inventory Scale - Culturally-Specific Distress
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
Secondary outcomes:
measure: Linear Change From Baseline to 14-month Follow-up in Social Support Assessed by the Multi-Sector Social Support Inventory
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
measure: Linear Change From Baseline to 14-month Follow-up in Access to Resources Assessed by the Satisfaction With Resources Scale
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
measure: Linear Change From Baseline to 14-month Follow-up in Access to Resources Assessed by the Difficulty Accessing Resources Scale
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
measure: Linear Change From Baseline to 14-month Follow-up in Quality of Life Assessed by the World Health Organization Quality of Life Assessment
timeFrame: Timepoints used in calculation: baseline, 3 months (mid), 6 months (post), 14 months (follow-up)
Other outcomes:
Locations:
city: Albuquerque
country: United States
facility: University of New Mexico
state: New Mexico
Study officials:
affiliation: University of New Mexico
name: Jessica R Goodkind, PhD
role: PRINCIPAL_INVESTIGATOR
References: