Clinical trial NCT06581445: Psychophysiological Effects of Birdsongs VS Music
Official title: Psychophysiological Effects of Birdsongs on Sadness: Compared With Music Between Depressed and Non-Depressed Participants
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Sadness
Keywords: Birdsongs
music
sadness
depressive symptoms
psychophysiological effects
Lead sponsor: Zhejiang University
Sponsor class: OTHER
First posted: 2024-09-03
Enrollment: 89
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: The main goal of this study is to learn the psychophysiological effects of birdsongs on sadness. The main questions it aims to answer are:

1. Can birdsongs alleviate sadness in a short term?
2. Can birdsongs have greater impact on sadness than music?
3. Can birdsongs alleviate sadness for both non-depressed and depressed participants?

Researchers will compare birdsongs to music (a active control) to see if birdsongs works to reduce sadness and also examined the psychophysiological effects of birdsongs in depressed and non-depressed participants.

Participants will:

go through the following stages: baseline, neutral control, 1st sadness induction, 1st intervention, calculation task, 2nd sadness induction, and 2nd intervention.

Detailed description: During the baseline phase, participants were instructed to sit quietly and relax. For the neutral control, they viewed an informative video demonstrating the process of plastic injection molding. As for the sadness induction, they were presented with sad film clips from either Hachi: A Dog\&#39;s Tale or My Brother and Sister. The order of the sad videos was randomized across participants. The intervention stages involved listening to either the cheerful Cuckoo Waltz music or a clip of birdsongs from laughing thrushes. The order of the interventions was randomized as well. The calculation task was employed as a distracter, enabling participants to return to a neutral state. Except for the computational task, the remaining six phases each had a duration of 6 minutes.

Eligibility criteria: Inclusion Criteria:

* Aged 18-30 years
* Right-handed
* No recent illness or medication use
* No history of neurological or psychiatric disorders
* Normal or corrected-to-normal visual acuity (myopic participants wore glasses)
* Normal hearing

Exclusion Criteria:

* Incapable of giving written informed consent to this study
* Acute high suicide risk at baseline assessment
* Psychosis

Primary outcomes:
measure: Self-Assessment Manikin (SAM)
timeFrame: Immediately after the baseline, immediately after the neutral control, immediately after each sadness induction, and immediately after each intervention.
measure: Revision of Positive Affect and Negative Affect Scale (PANAS-R)
timeFrame: Immediately after the baseline, immediately after the neutral control, immediately after each sadness induction, and immediately after each intervention.
measure: Mean of Normal-to-Normal Intervals (MeanNN)
timeFrame: Throughout the whole experiment, an average of 6 minutes for each stage.
measure: Standard Deviation of Normal-to-Normal Intervals (SDNN)
timeFrame: Throughout the whole experiment, an average of 6 minutes for each stage.
Secondary outcomes:
Other outcomes:
Locations:
city: Hangzhou
country: China
facility: Zhejiang University
state: Zhejiang
Study officials:
References: