Clinical trial NCT05553054: Drug Wastage : Observational Study in Intensive Care Units in France
Official title: Drug Wastage : Observational Study in Intensive Care Units in France
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Drug Use
Keywords: Intravenous (IV) drug
Waste
Intensive Care Unit (ICU)
Environmental sustainability
Drug wastage
Care Eco-design
Lead sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Sponsor class: OTHER
Collaborators: name: Sainte-Anne Military Teaching Hospital
First posted: 2022-09-23
Enrollment: 1066
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult patients hospitalized in intensive care units during the 24 hours of data collection.

Brief summary: Environmental awareness leads medical field to question its responsibility and possibilities for action.

Drug residues can have a major environmental impact as per their bioaccumulation, toxicity and persistence characteristics, depending on where they are discarded. In France, drug residues should be disposed of by incineration, but in practice, this is not systematic. Moreover, data on drug wastage in Intensive Care Units (ICU) are rare.

GAME-OVER observational study aims to evaluate drug wastage in ICU in France and to suggest ways to improve health care practices.

Detailed description: Observational study with data collection during a 24-hour business day. Data collected refer to healthcare team's practices and patients.

Collection starts when day shift starts (at 7:00 am) and ends when night shift leaves (at 7:00 am the following day).

Eligibility criteria: Inclusion Criteria:

* Adult patients hospitalized in intensive care units during the 24 hours of data collection.

Exclusion Criteria:

* Patient's opposition to participate in the study or patient family opposition if the patient is not able to be informed.

Primary outcomes:
measure: Ratio of overall wastage in milliliter (mL) of prepared and discarded IV drugs to overall volume in milliliter (mL) of prepared IV drugs.
timeFrame: 24 hours
Secondary outcomes:
measure: Reason for discarding drug residues
timeFrame: 24 hours
measure: Drug residues discarding process
timeFrame: 24 hours
measure: Use of enteral administration route
timeFrame: 24 hours
measure: Cost of overall IV drug wastage
timeFrame: 24 hours
Other outcomes:
Locations:
city: Charleville-Mézières
country: France
facility: Centre Hospitalier de Charleville-Mezieres
state: Ardennes
city: Strasbourg
country: France
facility: CHRU de Strasbourg
state: Bas-Rhin
city: Marseille
country: France
facility: Hôpital Nord
state: Bouches Du Rhône
city: Aurillac
country: France
facility: Centre Hospitalier d'Aurillac
state: Cantal
city: La Rochelle
country: France
facility: Groupe Hospitalier Littoral Atlantique
state: Charente-Maritime
city: Besançon
country: France
facility: CHU de Besançon
state: Doubs
city: Montélimar
country: France
facility: Centre Hospitalier de Montélimar
state: Drôme
city: Quincy-sous-Sénart
country: France
facility: Hôpital privé Claude Galien
state: Essonne
city: Brest
country: France
facility: HIA Clermont Tonnerre
state: Finistère
city: Brest
country: France
facility: CHRU de Brest
state: Finistère
city: Nîmes
country: France
facility: CHU de Nîmes
state: Gard
city: Bordeaux
country: France
facility: Clinique Saint Augustin
state: Gironde
city: Bordeaux
country: France
facility: CHU de Bordeaux - Hôpital Pellegrin
state: Gironde
city: Bordeaux
country: France
facility: HIA Robert Picqué
state: Gironde
city: Libourne
country: France
facility: Hôpital Robert Boulin
state: Gironde
city: Toulouse
country: France
facility: CHU de Toulouse - Hôpital Purpan
state: Haute Garonne
city: Quint-Fonsegrives
country: France
facility: Clinique la Croix du Sud
state: Haute-Garonne
city: Toulouse
country: France
facility: CHU de Toulouse - Hôpital Rangueil
state: Haute-Garonne
city: Toulouse
country: France
facility: Clinique Pasteur
state: Haute-Garonne
city: Le Puy-en-Velay
country: France
facility: Centre Hospitalier Emile Roux
state: Haute-Loire
city: Antony
country: France
facility: Hôpital privé d'Antony
state: Hauts-de-Seine
city: Clamart
country: France
facility: HIA Percy-Clamart
state: Hauts-de-Seine
city: Neuilly-sur-Seine
country: France
facility: Hôpital Américain de Paris
state: Hauts-de-Seine
city: Rennes
country: France
facility: CHU de Rennes
state: Ille-et-Vilaine
city: Chambray-lès-Tours
country: France
facility: CHRU de Tours
state: Indre-et-Loire
city: La Tronche
country: France
facility: CHU de Grenoble
state: Isère
city: Dax
country: France
facility: Centre Hospitalier de Dax
state: Landes
city: Mont-de-Marsan
country: France
facility: Centre Hospitalier de Mont-de-Marsan
state: Landes
city: Blois
country: France
facility: Centre Hospitalier Simone Veil
state: Loir-et-Cher
city: Saint-Nazaire
country: France
facility: Centre Hospitalier de Saint Nazaire
state: Loire-Atlantique
city: Orléans
country: France
facility: Centre Hospitalier d'Orléans
state: Loiret
city: Montbrison
country: France
facility: Centre Hospitalier du Forez
state: Loire
city: Saint-Priest-en-Jarez
country: France
facility: CHU de Saint-Etienne
state: Loire
city: Cahors
country: France
facility: Centre Hospitalier de Cahors
state: Lot
city: Angers
country: France
facility: CHU d'Angers
state: Maine-et-Loire
city: Saint-Lô
country: France
facility: Centre Hospitalier Mémorial de Saint-Lô
state: Manche
city: Reims
country: France
facility: CHU de Reims
state: Marne
city: Vannes
country: France
facility: Centre Hospitalier Bretagne Atlantique de Vannes
state: Morbihan
city: Lille
country: France
facility: CHU de Lille - Hôpital Huriez
state: Nord
city: Lille
country: France
facility: CHU de Lille - Hôpital Roger Salengro
state: Nord
city: Clermont-Ferrand
country: France
facility: CHU de Clermont-Ferrand
state: Puy-de-Dôme
city: Bron
country: France
facility: Hôpital Pierre Wertheimer
state: Rhône
city: Lyon
country: France
facility: Hôpital Edouard Herriot
state: Rhône
city: Lyon
country: France
facility: Clinique de la Sauvegarde
state: Rhône
city: Saint-Denis
country: France
facility: CHU Félix-Guyon
state: Réunion
city: Saint-Pierre
country: France
facility: CHU de la Réunion
state: Réunion
city: Meaux
country: France
facility: Grand Hôpital de l'Est Francilien
state: Seine-et-Marne
city: Amiens
country: France
facility: CHU d'Amiens
state: Somme
city: Trévenans
country: France
facility: Hôpital Nord Franche-Comté
state: Territoire De Belfort
city: Argenteuil
country: France
facility: Centre Hospitalier Victor Dupouy
state: Val d'Oise
city: Créteil
country: France
facility: Hôpital Henri Mondor
state: Val-de-Marne
city: Toulon
country: France
facility: HIA Sainte Anne
state: Var
city: Toulon
country: France
facility: Hôpital Sainte Musse
state: Var
city: Poitiers
country: France
facility: CHU de Poitiers
state: Vienne
city: Le Chesnay
country: France
facility: Centre Hospitalier de Versailles
state: Yvelines
city: Limoges
country: France
facility: CHU Dupuytren
city: Paris
country: France
facility: Hôpital Lariboisière
city: Paris
country: France
facility: Hôpital La Pitié-Salpétrière
city: Paris
country: France
facility: Hôpital Bichat
city: Mamoudzou
country: Mayotte
facility: Centre Hospitalier de Mayotte
city: Monaco
country: Monaco
facility: Centre Hospitalier Princesse Grace
Study officials:
affiliation: Sainte-Anne Military Teaching Hospital
name: Erwan D'ARANDA, MD
role: STUDY_DIRECTOR
References: