Clinical trial NCT04158999: Investigation of the Effect of Mother's Nutrition Status on Breast Milk Contents
Official title: Descriptive, Observational, Investigation of the Effect of Mother's Nutrition Status on Breast Milk Contents
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Breast Feeding
Lead sponsor: Halic University
Sponsor class: OTHER
Collaborators: name: Istanbul University - Cerrahpasa
First posted: 2019-11-12
Enrollment: 50
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Mothers whose babies were followed in the neonatal follow-up outpatient clinic of the Neonatal Intensive Care Unit of Istanbul University Faculty of Medicine, Department of Pediatrics and Fifty will be composed of 50 mothers who meet the sample selection criteria.

Brief summary: This study; this work; The aim is to investigate the effects of mothers' nutritional status on breast milk macro nutrients (carbohydrate, fat and protein).

Detailed description: Macronutrients in breast milk can be affected by various factors. The mothers will be taken in the first 24 hours after birth and their nutritional habits, socio-demographic characteristics, anthropometric characteristics of the mother, body mass index will be examined and newborn characteristics will be taken. 2 ml sample from colostrum will be analyzed with milk analyzer instrument. The mothers will be re-checked on the 5th day and their anthropometric properties will be obtained. The same procedure will be repeated on the 15th day after childbirth. At each control, the mother's last 24-hour feeding status will be taken and the nutritional values consumed by "BeBis" program will be examined.

Eligibility criteria: Inclusion Criteria:

* Follow-up of the infant in the Neonatal Intensive Care Unit, Istanbul Faculty of Medicine, Department of Pediatrics,

  * The mother is able to understand and answer the questions,
  * Single pregnancy,
  * The baby's birth week is 34 weeks or more,
  * The mother does not have a disease (Diabetes, hypertension, hypothyroidism, etc.) that may affect breast milk content.

Exclusion Criteria:

* Multiple pregnancy,

  * The birth week of the baby is less than 34 weeks.
  * Breastfeeding or breast problems in the mother,
  * The mother has a disease that may affect breast milk content (Diabetes, hypertension, hypothyroidism, etc.),
  * The mother is not willing to participate in the research,
  * A disease known to be transmitted by breast milk (HIV, hepatitis B, hepatitis C, etc.).

Primary outcomes:
measure: Human Milk Macro Nutrients
timeFrame: 15 Days
Secondary outcomes:
measure: Mother's Diet
timeFrame: 24 hours
Other outcomes:
Locations:
Study officials:
affiliation: Istanvbul University-Cerrahpasa
name: Gulçin Bozkurt, Assc. Prof.
role: STUDY_DIRECTOR
affiliation: Istanbul University
name: Asuman Çoban, Prof
role: STUDY_DIRECTOR
References:
citation: Butts CA, Hedderley DI, Herath TD, Paturi G, Glyn-Jones S, Wiens F, Stahl B, Gopal P. Human Milk Composition and Dietary Intakes of Breastfeeding Women of Different Ethnicity from the Manawatu-Wanganui Region of New Zealand. Nutrients. 2018 Sep 4;10(9):1231. doi: 10.3390/nu10091231.
citation: Bravi F, Wiens F, Decarli A, Dal Pont A, Agostoni C, Ferraroni M. Impact of maternal nutrition on breast-milk composition: a systematic review. Am J Clin Nutr. 2016 Sep;104(3):646-62. doi: 10.3945/ajcn.115.120881. Epub 2016 Aug 17.