Clinical trial NCT06272019: Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse
Official title: Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: The Retention of Iodine in Saliva Over the Time
The Comparison of Iodine in Saliva Between Gargle and Swab
Lead sponsor: Chulalongkorn University
Sponsor class: OTHER
First posted: 2024-02-22
Enrollment: 25
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: the participant will use iodine gargle in 2 method
Primary purpose: PREVENTION

Brief summary: To compare the iodine remaining in saliva between gargle method and swab method

Detailed description: separate the participant in 2 groups group 1 use iodine gargle with gargle method, after 48 hours use iodine gargle with swab method group 2 use iodine gargle with swab method, after 48 hours use iodine gargle with gargle method The researcher will collect saliva before use iodine gargle and after use at time 0, 5, 10, 20, 30, 60, 120 minutes

Eligibility criteria: Inclusion Criteria:

* Thai people
* no underlying disease, no pregnant
* at least 24 teeth
* No use iodine gargle
* No allergy to iodine and seafood
* No orthodontic and prosthetic treatment
* No ulcer and edentulous area
* Saliva flow rate in male (0.57+-0.3 ml/minute), in woman (0.41+-0.27 ml/minute)
* PI score lower than 0.6 (Green and vermillion index)

Exclusion Criteria:

* treatment orthodontic or prosthetic treatment currently
* Allergy to iodine between reach
* Can not participate

Primary outcomes:
measure: The rate of retention of iodine in saliva
timeFrame: 0, 5, 10, 20, 30, 60 and 120 minutes
measure: The comparison of the retention of iodine between gargle and swab
timeFrame: 0, 5, 10, 20, 30, 60 and 120 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Bangkok
country: Thailand
facility: Faculty of Dentistry, Chulalongkorn University
Study officials:
affiliation: Faculty of Dentistry, Chulalongkorn University
name: Wannakorn Sriar
role: PRINCIPAL_INVESTIGATOR
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