Clinical trial NCT06739577: Show Me How You Move and I Will Tell You Who You Are
Official title: Show Me How You Move and I Will Tell You Who You Are. Body Movement Analysis and Automatic Recognition of Associated Vestibular Impairment Patterns
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Vestibular Disease
Vestibular Function Disorder
Lead sponsor: Université Catholique de Louvain
Sponsor class: OTHER
First posted: 2024-12-18
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Vestibular loss diagnosed by senior ENT doctors with the gold standard ENT measures (caloric testing, head impulse test and/or vestibular evoked myogenic potential, ocular and cervical).

Brief summary: The aim of this experiment is to gain a better understanding of the body movement patterns of patients with balance disorders (following damage to the vestibular system), as well as their cognitive performance profile. To achieve this, we will need to assess the performance of both patients and healthy subjects with no balance disorders. We will be using a newly-developed artificial intelligence tool to analyze body movement patterns on the basis of participants' videos, and we will also be evaluating participants' performance in a few simple tests of reaction times to image presentations on computer and/or tablet/smartphone.

If you agree to take part in this experiment, you will be asked to perform a simple walking exercise in a corridor (filmed and supervised by a physiotherapist) as well as a few objective cognitive measurement tests (reaction time to attentional and vigilance tasks on computer and/or tablet/smartphone) and subjective tests (self-reported questionnaires) requiring around 40 minutes of investigation in total.

In the long term, the results of this research will make it easier to assess balance disorders in patients with vestibular pathology, and better quantify any cognitive difficulties they may have.


Eligibility criteria: For patients :

Inclusion Criteria:

* Age between 18 and 90 years old.
* Vestibular loss diagnosed by senior ENT doctors with the gold standard ENT measures (caloric testing, head impulse test and/or vestibular evoked myogenic potential, ocular and cervical).

Exclusion Criteria:

* Previous neurological disorders (stroke, dementia, ...)
* Current medication interfering with the testing (reducing reaction time).
* Visual difficulties interfering with the testing (Visual field reduction,...)
* Age below 18 years old.

For healthy controls :

Inclusion criteria :

- Age between 18 and 90 years old.

Exclusion criteria:

* Previous neurological disorders (stroke, dementia, ...)
* Current medication interfering with the testing (reducing reaction time)
* Visual difficulties interfering with the testing (Visual field reduction,...)
* Vertigo or balance complains or an history of previous vestibular disorder.
* Age below 18 years old.
* Not being able to understand the consigns of the task.

Primary outcomes:
measure: Neuropsychological measures
timeFrame: Through the entire study, approximately 24 months
measure: Neuropsychological measures
timeFrame: Through the entire study, approximately 24 months
measure: Neuropsychological measures
timeFrame: Through the entire study, approximately 24 months
measure: Neuropsychological measures
timeFrame: Through the entire study, approximately 24 months
measure: Walking activity
timeFrame: Through the entire study, approximately 24 months
Secondary outcomes:
Other outcomes:
Locations:
city: Brussels
country: Belgium
facility: Cliniques universitaires Saint-Luc
Study officials:
References: