Clinical trial NCT06146283: The Relationship Between Trunk Control and Hand Functions in Individuals With Parkinson's
Official title: The Relationship Between Trunk Control and Hand Functions in Individuals With Parkinson's
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Parkinson Disease
Lead sponsor: Sanko University
Sponsor class: OTHER
First posted: 2023-11-24
Enrollment: 30
Sex: ALL
Minimum age (years): 40
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: We included individuals diagnosed with Parkinson's between the ages of 40-70.

Brief summary: The trunk, which plays an integral role in postural stabilization, controls extremity movements by providing dynamic stabilization during performance. Trunk stability is thought to be a prerequisite for upper extremity functions and it is assumed that trunk control has an effect on hand functions. There is thought to be a strong relationship between postural control and fine motor functions. There are very few studies in the literature examining the effect of trunk control on hand functions in Parkinson's patients. Based on this, the aim of this study is; To investigate the relationship between trunk control and hand functions.

* Hypotheses of the study;
* Ho: There is no relationship between Trunk Control and hand functions in individuals with Parkinson's disease.
* H1: There is a relationship between Trunk Control and hand functions in individuals with Parkinson's disease

Detailed description: Parkinson's Disease (PD) is a progressive and neurodegenerative central nervous system disease characterized by loss of dopaminergic neurons in the substantia nigra. Rest tremor, bradykinesia, rigidity and postural instability are the four basic findings of Parkinson's disease. The progression of the disease varies from person to person, generally starting with unilateral findings, and after the third year, bilateral findings appear and progress from distal to proximal. Balance and postural control disorders also occur within two or three years. The first symptom seen in 80% of patients is rest tremor, which begins in the distal upper extremities. The trunk, which plays an integral role in postural stabilization, controls extremity movements by providing dynamic stabilization during performance. Trunk stability is thought to be a prerequisite for upper extremity functions and it is assumed that trunk control has an effect on hand functions. There is thought to be a strong relationship between postural control and fine motor functions. There are very few studies in the literature examining the effect of trunk control on hand functions in Parkinson's patients. Based on this, the aim of this study is; To investigate the relationship between trunk control and hand functions. Sociodemographic information will be recorded taking into account the answers to the questions in the personal information form prepared by the researcher. Parkinson's patients who meet the inclusion criteria; Rough Grip (Jamar Dynamometer), Nine Hole Peg Test (DDPT), Hoehn and Yahr Scale (HYÖ), Mini Mental Test, Quick-DASH, Duruöz Hand Index and Trunk Impairment Scale (GBÖ) will be performed by Physiotherapist Nursena KILIÇ.

As descriptive statistics; Mean and standard deviation or median and minimum-maximum values will be given for continuous variables specified by measurement, and frequency and percentage values will be given for qualitative variables. The suitability of continuous variables to normal distribution will be evaluated with the Kolmogorov-Smirnov test. In independent group comparisons; For continuous variables specified by measurement, if parametric test conditions are met, the significance test of the difference between two means or one-way ANOVA will be used. In cases where parametric test conditions are not met, Mann-Whitney U test or Kruskal-Wallis test will be used. In dependent measurement comparisons, the significance test of the difference between two pairs will be used for normally distributed data, and the Wilcoxon paired two sample test will be used for non-normally distributed data. The relationship between two continuous variables will be evaluated with Pearson or Spearman Rank correlation coefficients. p\<0.05 was considered statistically significant

Eligibility criteria: Inclusion Criteria:

* between the ages of 40 and 70,
* Being diagnosed with Parkinson's disease by a neurologist,
* Having a Mini Mental Test score of 24 and above,
* Modified Hoehn Yahr Scale score is 2 or less than 2,
* Having no additional neurological or orthopedic disease

Exclusion Criteria:

* Individuals with advanced cognitive problems and aphasia,
* Individuals with additional neurological disorders,
* Individuals who refuse to participate in the study,
* Individuals with vision and hearing problems will not be included.

Primary outcomes:
measure: Nine Hole Peg Test (9DPT)
timeFrame: 1 weeks
measure: Hand Grip Strength Measurement
timeFrame: 1 weeks
measure: Hoehn and Yahr Scale (HYS)
timeFrame: 1 weeks
measure: Mini Mental Test (MMT)
timeFrame: 1 weeks
measure: Quick-DASH
timeFrame: 1 weeks
measure: Duruöz Hand Index
timeFrame: 1 weeks
measure: Trunk Impairment Scale
timeFrame: 1 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Gaziantep
country: Turkey
facility: Sanko University
state: Şehitkamil
Study officials:
References: