Clinical trial NCT06835842: Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia
Official title: Effect of Rib Mobilization on Weaning Parameters From Mechanical Ventilator in Patients With Pneumonia
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Pneumonia
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-02-19
Enrollment: 60
Sex: ALL
Minimum age (years): 40
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters from mechanical ventilator in patients with pneumonia •

HYPOTHESES:

It will be hypothesized that there may be significant effect of rib mobilization on weaning parameters from mechanical ventilator in patients with pneumonia.

RESEARCH QUESTION:

Does rib mobilization have an effect on weaning parameters from mechanical ventilator in patients with pneumonia? measuring weaning parameters: on screen of mechanical ventilator : measuring respiratory rate, Tidal volume (TV), FiO2.

* Arterial blood gases (ABG) analyzer machine ABG is recorded daily (PH- PaO2 - PaCO2)
* Length of ICU stay: calculated by (admission date - discharge date
* Weaning success rate

Detailed description: Ventilator-associated pneumonia (VAP) represents a significant sub-set of (HAP) remains the most frequent intensive care unit (ICU)-acquired infection its incidence ranges from 9% to 27% of ventilated patients ,VAP is associated with an increased length of stay, mortality and health care costs, Pneumonia can result in chest wall stiffness, decreased mobility, limiting the range of motion during breathing and decreased lung compliance and impaired respiratory function , Rib mobilization: is an articular , non-invasive, passive technique that can be useful with acutely ill, hospitalized patients emphasizes the placement of a repetitive force to increase the range of motion of the posterior rib articulations and chest wall , lessening somatic dysfunction of the spine, stretches myofascial structures and improve respiratory mechanics So, this study will be conducted to distinguish between effect of rib mobilization and routine chest physiotherapy on weaning parameters among intubated pneumonic patients on mechanical vent.

Eligibility criteria: Inclusion Criteria:

1. Patient's age ranged from 40- 50 years old from both genders.
2. Diagnosed with pneumonia and need invasive mechanical ventilation support.
3. Stable oxygen saturation (SpO2 more than 85, (FiO2) 0.6 or less, PEEP less than 10 Cm H2O).
4. mean arterial pressure \> 75 mmHg and urine output \> 1 mL/kg/h;
5. Patients with Glasgow coma scale (GCS) \> 8T
6. Unconscious and semi-conscious patients. -

Exclusion Criteria:

1. Unstable hemodynamics
2. Unstable neurological problems e.g. (epileptic seizures -hyperthermia).
3. Unstable chest wall e.g. (multiple rib or vertebral fractures)
4. Increase intracranial pressure (\>20 mmHg for \>5 min).
5. Undrained pneumothorax, recent pulmonary surgery

Primary outcomes:
measure: Arterial blood gases
timeFrame: at least 10 consecutive days
measure: Respiratory rate (RR)
timeFrame: at least 10 consecutive days
measure: Tidal volume (TV)
timeFrame: at least 10 consecutive days
Secondary outcomes:
measure: Length of hospital stay
timeFrame: at least 10 consecutive days
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Hoda gaber elsaid
city: Cairo
country: Egypt
facility: Hoda gaber elsaid
Study officials:
affiliation: Cairo University
name: Azza Abd El Aziz Abd El Hady, professor
role: STUDY_CHAIR
affiliation: Cairo University
name: Mohammed Abd Hakim El-Nadi, professor
role: STUDY_CHAIR
References: