Clinical trial NCT06980324: Neuromuscular Inhibition Technique on Iliotibial Band Friction Syndrome
Official title: Effect of Integrated Neuromuscular Inhibition Technique on Iliotibial Band Friction Syndrome
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Iliotibial Band Syndrome
Keywords: integrated neuromuscular inhibition technique
iliotibial band friction syndrome
muscle energy technique
ischemic compression
positional release
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-05-20
Enrollment: 40
Sex: ALL
Minimum age (years): 30
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to find the effect of integrated neuromuscular inhibition technique for iliotibial band in iliotibial band friction syndrome on pain intensity level, pressure pain threshold, knee range of motion, knee function and knee angle . The main questions it aims to answer are:

* Is there an effect of integrated neuromuscular inhibition technique for iliotibial band on pain intensity level in iliotibial band friction syndrome?
* Is there an effect of integrated neuromuscular inhibition technique for iliotibial band on pressure pain threshold in iliotibial band friction syndrome?
* Is there an effect of integrated neuromuscular inhibition technique for iliotibial band on knee range of motion in iliotibial band friction syndrome?
* Is there an effect of integrated neuromuscular inhibition technique for iliotibial band on knee function in iliotibial friction syndrome? Is there an effect of integrated neuromuscular inhibition technique for iliotibial band on knee angle in iliotibial band friction syndrome?

Researchers will compare integrated neuromuscular inhibition technique to conventional physiotherapy to see if integrated neuromuscular inhibition technique works to treat iliotibial band syndrome.

Participants will:

* Take sessions for 2 weeks
* Visit the department 3 times per week


Eligibility criteria: Inclusion Criteria:

* Body mass index from 25-30 kg/m2
* Both males and females will be included their age from 30-50.
* The subjects that will be included in the study will be referred from orthopeadic physician with iliotibial band friction syndrome with these signs and symptoms
* local tenderness of the lateral knee inferior to the epicondyle and superior to the joint line
* Pain with ITBS can be reported anywhere along the iliotibial (IT) band from the lateral thigh to the lateral femoral condyle and Gerdy's tubercle.
* Pain is most intense at approximately 30 degrees of knee.
* A sharp, burning pain when the practitioner presses on the lateral epicondyle during knee flexion and extension associated with one of these cases:
* Tibiofermoral knee pain.
* Patellofemoral knee pain.
* osteoarthritis with medial knee joint pain
* Lateral patellar pressure syndrome.
* Medial meniscus degeneration.
* Excessive lateral pressure syndrome

Exclusion Criteria:

* Traumatic injury to the knee joint within 6 months.
* Surgical procedure on the affected knee within the last 12 months.
* Meniscus injury
* knee ligaments injury
* Malignancies, tumors or infections associated with the knee joint.
* Impaired thermal sensation over the knee.
* Subject with psychiatric disorder.
* Peripheral vascular disease.
* Severe joint deformity.
* Current back or ankle pain.
* Rheumatoid arthritis.
* Lower extremity fracture.
* Neurological defecit or movement disorder.
* Athletes.
* Menopause
* Pregnancy
* Auto immune disease
* Chronic disease (Diabetes mellitus and Hypertension)

Primary outcomes:
measure: Pain intensity
timeFrame: after 2 weeks
measure: lower extremity function
timeFrame: after 2 weeks
measure: Knee range of motion
timeFrame: after 2 weeks
Secondary outcomes:
measure: pressure pain threshold
timeFrame: after 2 weeks
measure: knee angle
timeFrame: after 2 weeks
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Faculty of physical therapy, Cairo university
Study officials:
affiliation: Cairo University
name: AMIR MO Saleh, Professor of Physical Therapy
role: STUDY_CHAIR
affiliation: Cairo University
name: Doaa RA Elazab, Assistant professor
role: STUDY_DIRECTOR
affiliation: Faculty of Medicine Banha University
name: Hassan HU Ahmed, Orthopedic Surgery Professor
role: STUDY_DIRECTOR
affiliation: Cairo University
name: Esraa TA Farouk, Physical therapist
role: PRINCIPAL_INVESTIGATOR
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