Clinical trial NCT01633736: Targeted Hip Strength Training in Children With Cerebral Palsy (CP)
Official title: Targeted Hip Progressive Resistance Training to Improve Single Leg Balance and Walking in Children With Cerebral Palsy
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE3
Conditions: Cerebral Palsy
Keywords: single blinded
randomised
controlled
physiotherapy
children
cerebral palsy
Lead sponsor: University of Nottingham
Sponsor class: OTHER
First posted: 2012-07-04
Enrollment: 20
Sex: ALL
Minimum age (years): 7
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study's main aim is to look at targeted strength training for muscles at the hips. Specifically to consider whether targeted strength training not only effects strength of the specific muscles but also ability to stand on one leg (single leg balance) as well as walking in children with cerebral palsy? This study is a feasibility of method of investigation.

Detailed description: This study is focusing on functional change. The reasoning is that if the targeted strength training is effective at improving hip muscle contribution to stability then single leg balance may be improved. This may be functionally evident when weight bearing is taken by say the left leg in gait (percentage stance phase of gait) and as a consequence the opposing swing phase will be optimised as measured by stride. Thus the research question is does strengthening of the rotating and sideways moving hip muscles improve the walking of children with CP as measured by appropriate aspects of gait? Secondly, does this targeted strengthening also increase duration of single leg balance which is a simple easy to use measure in the community without the need for specialised equipment? The primary outcome measure will use a laboratory based 4 camera Codsmotion (CODA) biomechanical analysis system to measure stride (a) and percentage duration of stance phase of gait (b). Secondarily the duration of single leg balance in terms of seconds will be recorded. Gross motor functional and quality of life as also being assessed. The intervention is strengthening which will be implemented with the principles of progressive resistance training. Children with CP's therapists would ask for this type of intervention to be carried out

Eligibility criteria: Inclusion Criteria:

* Children with CP aged between 7-16 years having sufficient cognition to undertake a strength training program

Exclusion Criteria:

1. non-ambulation children or those unable to walk 5 meters independently (without walking aid),
2. lower limb surgery within 12 months,
3. botox within 6 months,
4. oral muscle relaxant medication
5. significant learning difficulty
6. Any concurrent condition which would be contraindicated to progressive resistance training such as unmanaged high blood pressure, cardiac pathology or uncontrolled epilepsy
7. Where at baseline assessment finds no weakness in the muscles under investigation
8. concurrent or within 6 months involvement in any other research study
9. Non consent to General Practitioner (GP) notification.

Primary outcomes:
measure: Gait parameter
timeFrame: baseline, plus 8 weeks and plus 8 weeks (exit point)
Secondary outcomes:
measure: Gross Motor Function Measure (GMFM)
timeFrame: Baseline, plus 8 weeks and plus 8 weeks (exit)
Other outcomes:
Locations:
city: Nottingham
country: United Kingdom
facility: Divison of Physiotherapy, School of Nursing, Midwifery and Physiotherapy, The University of Nottingham
state: Nottinghamshire
Study officials:
affiliation: The University of Nottingham
name: Grahame Pope, MPhil, BSc
role: PRINCIPAL_INVESTIGATOR
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