Clinical trial NCT02846077: Multi-scale Modeling of Sleep Behaviors in Social Networks
Official title: Multi-scale Modeling of Sleep Behaviors in Social Networks
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Healthy Volunteers
Keywords: sleep
social networks
undergraduates
mood
circadian rhythms
Lead sponsor: Brigham and Women's Hospital
Sponsor class: OTHER
Collaborators: name: Massachusetts Institute of Technology
name: Harvard University
First posted: 2016-07-27
Enrollment: 729
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: College undergraduates

Brief summary: The project is designed to document in college undergraduates the relationships among sleep/wake timing and duration, use of mobile phones and other electronic devices, food timing and content, self-reported mood and physiological measures.

Detailed description: College undergraduates are studied in cohorts of \~ 50 in fall or spring semesters. They complete diaries once in the morning and once in the evening about sleep/wake timing, timing of social and school activities, and mood. They wear physiological sensors. They install (1) an application on their mobile phone that tracks timing, duration and de-identified sender/recipient of phone calls and text messages, use of internet or apps (but not the content or names of those internet sites and apps) and (2) meal content and timing. They also spend at least one overnight session providing saliva samples for later assay for hormones.

Eligibility criteria: Inclusion Criteria:

* undergraduate at institution at which we have permission to perform study
* owning a mobile device on which the phone app can be installed
* ability to wear the wrist-worn sensors

Exclusion Criteria:

* no travel outside one time zone starting approximately 2 weeks before monitoring begins through end of approximately one month of monitoring.
* participation in a prior group studied

Primary outcomes:
measure: Timing of sleep and wake
timeFrame: Approximately one month
measure: Timing of phone use (e.g., mobile phone calls, text messages, applications and internet use)
timeFrame: Approximately one month
Secondary outcomes:
measure: Mood
timeFrame: Approximately one month
measure: Activity levels
timeFrame: approximately one month
measure: Light exposure levels
timeFrame: approximately one month
measure: Food choice
timeFrame: approximately one month
measure: Circadian phase
timeFrame: one day
measure: Electrodermal activity
timeFrame: approximately one month
measure: Timing of meals
timeFrame: approximately one month
Other outcomes:
Locations:
city: Boston
country: United States
facility: Brigham and Women's Hospital
state: Massachusetts
Study officials:
affiliation: Brigham and Women's Hospital
name: Elizabeth B Klerman, MD PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Fischer D, McHill AW, Sano A, Picard RW, Barger LK, Czeisler CA, Klerman EB, Phillips AJK. Irregular sleep and event schedules are associated with poorer self-reported well-being in US college students. Sleep. 2020 Jun 15;43(6):zsz300. doi: 10.1093/sleep/zsz300.
citation: McHill AW, Phillips AJ, Czeisler CA, Keating L, Yee K, Barger LK, Garaulet M, Scheer FA, Klerman EB. Later circadian timing of food intake is associated with increased body fat. Am J Clin Nutr. 2017 Nov;106(5):1213-1219. doi: 10.3945/ajcn.117.161588. Epub 2017 Sep 6.