Clinical trial NCT00589719: Asthma in the Delta Region of Arkansas (ADRA): Prevalence and Morbidity
Official title: Asthma in the Delta Region of Arkansas (ADRA): Prevalence and Morbidity
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Asthma
Keywords: Asthma; minority; low-income; African American; Arkansas
Lead sponsor: Arkansas Children's Hospital Research Institute
Sponsor class: OTHER
First posted: 2008-01-10
Enrollment: 964
Sex: ALL
Minimum age (years): 4
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: During the 2005-2006 school year, primary caregivers of all students aged 4-17 years attending public school in Eudora and Marvell Arkansas were asked to complete an asthma screening survey regarding their child. The schools are located in two non-contiguous counties in the Delta region of Arkansas and are in rural low-income areas of the state where more than one-third of families with children 5-17 years old meet the 2000 poverty line (Census bureau).

Brief summary: The purpose of the study is to conduct a cross-sectional study to examine asthma prevalence and morbidity in a predominately minority, low-income population in rural Arkansas.

Detailed description: Asthma is the leading chronic disease of childhood in the United States and an important public health concern in Arkansas. Arkansas, a predominately rural state, has one of the leading mortality rates in the nation for African Americans. The specific aims of the study will examine asthma prevalence in children age 4-17 years old in public schools in Eudora and Marvell Arkansas. The study will also examine asthma morbidity among identified asthmatics by characterizing activity limitation, days missed from school, daytime and nocturnal symptoms, healthcare utilization and medication use. The specific aims of the current study will provide novel data on an understudied population of asthmatics and will test our working hypotheses that pediatric asthma prevalence in the Delta region of Arkansas is higher than national estimates; and asthma diagnosis is related to significant morbidity among rural asthmatics.

Eligibility criteria: Inclusion Criteria:

* Children aged 4-17 years, enrolled in the public schools in Eudora and Marvell Arkansas.

Exclusion Criteria:

* Children aged 18 or older enrolled in the public schools in Eudora and Marvell Arkansas were excluded.

Primary outcomes:
measure: The findings suggest that asthma diagnosis and active symptoms are prevalent among this predominately minority and low-income rural population in the Arkansas region of the Mississippi Delta.
timeFrame: One year
Secondary outcomes:
measure: High rates of inadequately controlled asthma are evidenced by activity limitation, medication use and increased healthcare utilization.
timeFrame: One year
Other outcomes:
Locations:
city: Little Rock
country: United States
facility: Arkansas Children's Hospital Research Institute
state: Arkansas
Study officials:
affiliation: University of Arkansas
name: Tamara T. Perry, M.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Galant SP, Crawford LJ, Morphew T, Jones CA, Bassin S. Predictive value of a cross-cultural asthma case-detection tool in an elementary school population. Pediatrics. 2004 Sep;114(3):e307-16. doi: 10.1542/peds.2003-0575-F.