Clinical trial NCT06845436: Effects of Combined High Intensity Interval Training and Resistance Training
Official title: Effects of Combined High Intensity Interval Training and Resistance Training on Body Composition, Blood Pressure, and Cardiorespiratory Fitness in Obese Hypertensive Men
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Hypertension
Keywords: hypertension.
obesity
High Intensity Interval Training
resistance training
blood pressure
Lead sponsor: Prince Sattam Bin Abdulaziz University
Sponsor class: OTHER
First posted: 2025-02-25
Enrollment: 60
Sex: MALE
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Background: Hypertension has long been considered as a major risk factor for cardiovascular disease representing a high public health concern.

Objectives: the purpose of this study is to evaluate the effects of combined HIIT and resistance training on body composition, blood pressure, and cardiorespiratory fitness in obese hypertensive men.

Methods: This study will make use of sixty obese hypertensive men aged 40 to 60 years. All participants meeting the eligibility criteria will be assigned to one of three groups; combined HIIT and resistance group, HIIT only group or control group. Combined exercise group subjects will undergo weekly three sessions of both HIIT and resistance training for sixteen weeks. The HIIT session will involve four four-minute high-intensity intervals with an intensity of at 80-95% of the HRmax interspersed with two-minute active recovery intervals with intensity of 40% to 60% of the HRmax. The resistance training session will be composed of eight exercises perform 3 sets of 8-12 repetitions with an intensity of 80% of the subject's estimated 1-RM. The HIIT only group perform 12 weeks of HIIT only. The control group subjects will be instructed not to change their usual daily physical activities routine and instructed to abstain from practicing any exercise regimens during the 12-week study period. Body composition measures, blood pressure and VO2peak will be assessed at baseline and at the end of the study period.

Results: All the outcome variables will be assessed at baseline and 12 weeks following the treatment period.


Eligibility criteria: Inclusion Criteria:

* men aged between 40 and 60 years old,
* have been diagnosed with clinical stage 1 or 2 hypertension,
* being obese with body mass index more than 30 kg/m2
* physically inactive

Exclusion Criteria:

* musculoskeletal problems that may limit their ability to participate in resistance or HIIT programs
* diabetes mellitus
* a history of respiratory or chronic heart disease

Primary outcomes:
measure: blood pressure in mmhg
timeFrame: 12 weeks
measure: peak oxygen consumption in ml/kg/min
timeFrame: 12 weeks
measure: body weight in Kg
timeFrame: 12 weeks
measure: body mass index in kg/m2
timeFrame: 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Riyadh
country: Saudi Arabia
facility: Prince Sattam bin Abdulaziz University
state: Alkharj
Study officials:
References: