Clinical trial NCT03665324: Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.
Official title: Atrial Function and Supraventricular Arrhythmia of the Veteran Athlete.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Supraventricular Arrhythmias
Keywords: Supraventricular arrhythmias
veteran athlete
ECG
ETT
Lead sponsor: Rennes University Hospital
Sponsor class: OTHER
First posted: 2018-09-11
Enrollment: 100
Sex: ALL
Minimum age (years): 35
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Veteran athletes who consulted in the Sports Medicine Department between January 1, 2010 and January 1, 2017

Brief summary: Supraventricular arrhythmias (including atrial fibrillation) are the most common arrhythmias of the veteran athlete and have a major impact in terms of morbidity and mortality. Although moderate sports practice has been shown to decrease the occurrence of these arrhythmias, it has also been shown that very intense athletic activity is associated with an increased risk of developing atrial fibrillation. The pathophysiological mechanism is not clearly understood. However, it has already been shown that intensive sports practice leads to electrical and morphological atrial remodeling, which could be the cause of the occurrence of supraventricular arrhythmias for these athletes.

For sedentary patients, two major tools predict the risk of the onset of supraventricular arrhythmia: the electrocardiogram (ECG) and transthoracic echocardiography (ETT), particularly with the study of atrial function by the analysis of myocardial deformities.

Detailed description: No studies have tested these two tools for the evaluation of atrial remodeling of the veteran athlete to predict which ones are at risk of developing supraventricular arrhythmias.

However, the identification of predictive factors would make it possible to identify at-risk athletes and thus provide them with adapted sporting practice advice and personalized follow-up.

The aim of the study is to evaluate the relationship between atrial remodeling assessed by ECG and ETT with the occurrence of supraventricular arrhythmia by comparing an athlete group with supraventricular arrhythmia with a control group of healthy athletes.

Eligibility criteria: Inclusion Criteria:

* Supraventricular arrhythmia group : Veteran athletes with documented paroxysmal supraventricular arrhythmias.
* Control Group : Veteran athletes without documented supraventricular arrhythmia.

Exclusion Criteria:

* Any cardiopathy (valvulopathy, coronary heart disease, etc.).
* Minor patients,
* Major patients subject to legal protection (legal safeguards, guardianship)
* Persons deprived of their liberty
* Patients opposed to the use of their personal data.

Primary outcomes:
measure: Study of atrial function by analysis of myocardial strain.
timeFrame: At the inclusion day
Secondary outcomes:
Other outcomes:
Locations:
city: Rennes
country: France
facility: Rennes University Hospital
Study officials:
affiliation: Rennes University Hospital
name: frederic SCHNELL, MD
role: PRINCIPAL_INVESTIGATOR
References: