Clinical trial NCT04589637: Factors Influencing the Deterioration From Cognitive Decline of Normal Aging to Dementia Among Nursing Home Residents
Official title: Factors Influencing the Deterioration From Cognitive Decline of Normal Aging to Dementia Among Nursing Home Residents
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Dementia
Lead sponsor: Jordan University of Science and Technology
Sponsor class: OTHER
First posted: 2020-10-19
Enrollment: 182
Sex: ALL
Minimum age (years): 60
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Convenience sampling of 182 participants was used to obtain moderate size correlation (r = 0.35), given a power of 0.80, two-sided Type I error rate of p = 0.0167, based on nQuery calculation \[16\]. The participants were recruited from 5 holistic nursing homes, including private and public nursing homes, located in the center of Jordan. Inclusion criteria were as follows: Jordanian participants, aged 60 years and older, and living in nursing homes. Exclusion criteria were neurological disorders, such as stroke or brain injury.

Brief summary: Background: A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents. This study aimed to identify and examine the association between medical factors (number of comorbidities, hospitalization, disability, depression, frailty and quality of life) and moderate cognitive impairment or dementia in nursing homes residents.

Methods: A cross-sectional design was used in this study. Convenience sampling of 182 participants was conducted in nursing homes located in the central part of Jordan. Montreal cognitive assessment (MoCA) was used to screen both MCI and moderate cognitive impairment or dementia. Bivariate analysis, including t-test and ANOVA test, and logistic and linear regression models were used to examine and identify the medical factors associated with moderate cognitive impairment or dementia compared to mild cognitive impairment.


Eligibility criteria: Inclusion Criteria:

* Jordanian participants, aged 60 years and older, and living in nursing homes

Exclusion Criteria:

* neurological disorders, such as stroke or brain injury

Primary outcomes:
measure: moderate cognitive impairment
timeFrame: May, 2018-May, 2019
Secondary outcomes:
Other outcomes:
Locations:
city: Amman
country: Jordan
facility: Nursing homes
Study officials:
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