Clinical trial NCT06605677: Knowledge Attitude and Practice Regarding Bloodstream Bacterial Infections and Antibiotics Usage Among Doctors.
Official title: Knowledge Attitude and Practice Regarding Bloodstream Bacterial Infections and Antibiotics Usage Among Doctors in a Tertiary Hospital in Al Ain City, UAE: A Cross-Sectional Descriptive Study.
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Bacteremia
Antimicrobial Stewardship
Antibiotic Use
Antibiotic Abuse
Keywords: bacteremia
antimicrobial resistance
antimicrobial stewardship
healthcare workers
antibiotic use
antibiotic abuse
Lead sponsor: Abu Dhabi Health Services Company
Sponsor class: OTHER_GOV
First posted: 2024-09-20
Enrollment: 100
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Licensed, practicing physicians, multinational

Brief summary: This study is designed to use a questionnaire to assess doctors' knowledge, attitudes, and practices regarding bloodstream bacterial infections and antibiotic use in Tawam and Al Ain tertiary Hospitals (both hospitals have the same medical team) in Al Ain City, UAE.

Detailed description: Background: Bloodstream bacterial infection is a serious medical problem and one of the leading causes of death worldwide among all age groups. Appropriate and early antibiotic use has been associated with better outcomes based on many clinical trials. On the other hand, misuse and abuse of antibiotics have been linked to long hospital stays, significant morbidity and mortality, increased medical costs and rising antimicrobial resistance (AMR). Statistics in hospitals involved in the study, showed increased antibiotic consumption compared to previous years and other regional healthcare facilities. Rates of AMR in the UAE have increased significantly in the last decade, based on the 2022 annual report.

Aims and objectives This study will assess knowledge, attitude and practice regarding bloodstream bacterial infections and antibiotics use among doctors. It is a questionnaire-based cross-sectional descriptive study that will be conducted at Tawam and Al Ain Hospitals (tertiary hospital, both hospitals have the same medical team).

The investigators want to explore the degree of knowledge and attitude, assess the appropriate usage of antibiotics among doctors in different subspecialties, assess any possible barriers, and find solutions such as medical education for this challenging medical problem.

Eligibility criteria: Inclusion Criteria:

All physicians with valid medical licenses working in Tawam and Al Ain tertiary hospitals

Exclusion Criteria:

Infectious diseases physicians and Microbiologists

Primary outcomes:
measure: Understanding physician knowledge on antibiotic use in bacterial bloodstream infections (bacteremia).
timeFrame: 1 year
measure: Understanding physician attitude on antibiotic use in bacterial bloodstream infections (bacteremia).
timeFrame: 1 year
measure: Understanding physician practices on antibiotic use in bacterial bloodstream infections (bacteremia).
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Al Ain
country: United Arab Emirates
facility: Tawam and Al Ain Hospital
Study officials:
affiliation: Abu Dhabi Health Services Co-SEHA
name: Noura Saif Alnuaimi, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Abu Dhabi Health Services Co-SEHA
name: Ahmed Al Hammadi, MD
role: STUDY_CHAIR
References:
citation: Thomsen J et al. United Arab Emirates Surveillance of Antimicrobial Resistance Annual Report 2022.
citation: Labelle A, Juang P, Reichley R, Micek S, Hoffmann J, Hoban A, Hampton N, Kollef M. The determinants of hospital mortality among patients with septic shock receiving appropriate initial antibiotic treatment*. Crit Care Med. 2012 Jul;40(7):2016-21. doi: 10.1097/CCM.0b013e318250aa72.
citation: Zahar JR, Timsit JF, Garrouste-Orgeas M, Francais A, Vesin A, Descorps-Declere A, Dubois Y, Souweine B, Haouache H, Goldgran-Toledano D, Allaouchiche B, Azoulay E, Adrie C. Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality. Crit Care Med. 2011 Aug;39(8):1886-95. doi: 10.1097/CCM.0b013e31821b827c.
citation: Kreger BE, Craven DE, McCabe WR. Gram-negative bacteremia. IV. Re-evaluation of clinical features and treatment in 612 patients. Am J Med. 1980 Mar;68(3):344-55. doi: 10.1016/0002-9343(80)90102-3.
citation: Bearman GM, Wenzel RP. Bacteremias: a leading cause of death. Arch Med Res. 2005 Nov-Dec;36(6):646-59. doi: 10.1016/j.arcmed.2005.02.005.