Clinical trial NCT05506813: Comparative Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
Official title: Comparative Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease
Balance; Distorted
Postural; Defect
Keywords: Parkinson Disease
Balance; Distorted
Postural; Defect
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-08-18
Enrollment: 20
Sex: ALL
Minimum age (years): 50
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: total 20 Participants will be divided in two groups. In group A patients will receive cognitive training along with conventional therapy. while in Group B Participants will receive motor dual task training along with conventional therapy.
Primary purpose: TREATMENT

Brief summary: To Compare Effects of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients

Detailed description: This study will be conducted to compare the Comparative Effect of Cognitive and Motor Dual Task Training on Balance and Quality Of Life in Parkinson's Patients. total 20 Patients will be recruited according to the inclusion criteria and data will be collected from the Riphah Rehabilitation center Lahore, Muhammadi Medical trust hospital Lahore. Time Up and Go test (TUG) Parkinsons disease Questionnaire 39 (PDQ-39) will be used as data collection tool. To assess the balance and quality of life in parkinson's patients. Patients will be allocated to intervention group by randomization. After approval from ethical committee, data collection will be started and informed consent will be taken from all patients

Eligibility criteria: Inclusion Criteria:

* A stage I-II-III Hoehn and Yahr scale consultant neurologist's diagnosis of Parkinson's disease
* A stable medication schedule both before and during the trial period
* can walk without assistive aid

Exclusion Criteria:

* Other neurological conditions in additions to Parkinson's disease such as CVA, Head injuries, Trauma
* Any Musculoskeletal condition e.g., total knee replacement surgery and rheumatoid arthritis
* Sensory impairments (vestibular dysfunctions)

Primary outcomes:
measure: time up and go test
timeFrame: 9 months
measure: Parkinson Disease Questionnaire-39 (PDQ-39).
timeFrame: 9 months
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Riphah International University
state: Fedral
Study officials:
affiliation: Riphah International University
name: Zeest Hashmi, MSNMPT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bordignon A, Devita M, Sergi G, Coin A. "Cerebellar cognitive reserve": a possible further area of investigation. Aging Clin Exp Res. 2021 Oct;33(10):2883-2886. doi: 10.1007/s40520-021-01795-1. Epub 2021 Feb 17. No abstract available.
citation: Onder H, Ozyurek O. The impact of distinct cognitive dual-tasks on gait in Parkinson's disease and the associations with the clinical features of Parkinson's disease. Neurol Sci. 2021 Jul;42(7):2775-2783. doi: 10.1007/s10072-020-04874-9. Epub 2020 Nov 4.
citation: Bouscary A, Quessada C, Rene F, Spedding M, Turner BJ, Henriques A, Ngo ST, Loeffler JP. Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. Semin Cell Dev Biol. 2021 Apr;112:82-91. doi: 10.1016/j.semcdb.2020.10.008. Epub 2020 Nov 5.