Clinical trial NCT06308237: Effects of Resisted Versus Balance Exercises on Cognitive And Motor Function In Patients With Mild Cognitive Impairment
Official title: Effects of Resisted Versus Balance Exercises on Cognitive And Motor Function In Patients With Mild Cognitive Impairment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Mild Cognitive Impairment
Keywords: Cognition
Motor control
Randomized clinical trial
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-03-13
Enrollment: 70
Sex: ALL
Minimum age (years): 60
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Mild cognitive impairment affects older adults and it includes memory and attentions deficits, and problem-solving difficulties in activities of daily living. Resisted exercises is considered a viable strategy to improve balance and motor function in older population. Balance exercises comprises proprioceptive, visual and motor learning to a larger degree and has positive effects on memory and spatial cognition and improves balance and motor function. This study aims to determine the effects of resisted and balance exercises on cognition and motor function in patients with mild cognitive impairment.

Detailed description: This randomized clinical trial will be conducted at Aziz Bhatti Shaheed Teaching Hospital Gujrat in seven months after approval of synopsis. The sample size for this trial is 78 patients with MCI. The participants will be randomly allocated into two groups using Online Randomization tool. Group A will receive resisted exercises for 30 minutes and Group B will receive balance exercises for 30 minutes. Participants will receive 3 sessions on alternate days per week for 12 weeks.Montreal Cognitive Assessment (MoCA) and Computerized battery test will be used to assess cognitive impairment, Mini-besTest and Time Up and Go Test (TUG) for balance and motor function.Data will be entered and analysed by using SPSS 26 software.

Eligibility criteria: Inclusion Criteria:

1. Patients with Mild Cognitive Impairment. (Having score between 18 - 24) on MoCA.
2. Participants with Both Genders will be included .
3. The Age limit for the participants will be 60 to 75 years.
4. Patients having Independence of life (ability to walk independently without any walking aid).

Exclusion Criteria:

1. Previous and current History Cardiovascular, neurological, psychiatric and motor disorders like (fractures, diagnosis of Osteoporosis)
2. Patients taking any medication for mild cognition.
3. Depressive symptoms, acute and chronic conditions that would preclude exercise, regular exercise (\>30 min/day, \>3days/week).
4. Patients having estrogen replacement therapy.
5. Simultaneous participation in other studies.
6. Regular physical activity (once a week during the last 3 months); physio therapeutic treatment in the last 3 months.
7. Diseases that promote incapacity; severe visual deficiency; recurrent vertigo; and uncontrolled systemic arterial hypertension.

Primary outcomes:
measure: MoCA (Montreal Cognitive Assessment )
timeFrame: 14th week
measure: Mini-Balance Evaluation Systems Test (BESTest).
timeFrame: 16th week
measure: Timed UP and GO Test (TUG) :
timeFrame: 16th week
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Riphah International University
state: Punjab
Study officials:
affiliation: Riphah International University
name: Muhammad Kashif, Phd-PT
role: STUDY_CHAIR
References: