Clinical trial NCT04812145: Role of Hypofractionated Radiotherapy With Concurrent Gemcitabine in Treatment of Urinary Bladder Carcinoma
Official title: Role of Hypofractionated Radiotherapy With Concurrent Gemcitabine in Treatment of Urinary Bladder Carcinoma
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Urinary Bladder Cancer
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2021-03-23
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Urinary bladder cancer patient histologically proved Transitional cell carcinoma received concurrent chemoradiation with gemcaitabine

Brief summary: Estimate the response to modified hypofractionated radiotherapy concurrent with Gemcitabine in urinary bladder cancer patients .

Estimate local control, relapse free survival, overall survival and bladder preservation rate. Evaluate the toxicity of a modified hypofractionated chemoradiotherapy protocol for patients with invasive bladder cancer.


Eligibility criteria: Inclusion Criteria:

- Pathologically confirmation of transitional cell carcinoma . Non metastatic invasive bladder cancer (TNM0) Any age group ≥ 18 years. Non pregnant female patients.

Exclusion Criteria:

- Other pathology than Transitional cell carcinoma Metastatic Patient Age less than 18 years

Primary outcomes:
measure: Response to hypofractionated radiotherapy concurrent with Gemcitabine in urinary bladder cancer
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
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