Clinical trial NCT06500039: Positive Psychological Interventions for Patients With Multiple Sclerosis
Official title: The Effect of Positive Psychological Interventions on Quality of Life and Well-Being in Patients With Multiple Sclerosis
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Multiple Sclerosis
Keywords: Multiple sclerosis, Quality of Life, Well-Being
Lead sponsor: Abant Izzet Baysal University
Sponsor class: OTHER
First posted: 2024-07-15
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The research was planned as a randomized controlled prospective study. It will be carried out in two groups.
Primary purpose: SUPPORTIVE_CARE

Brief summary: This study aims to determine the effectiveness of positive psychological interventions on the quality of life and well-being levels of patients with multiple sclerosis.Two groups will be selected as intervention and control groups. An intervention method consisting of three good things in life and gratitude activities, each lasting two weeks, was determined for the intervention group. An activity was planned for control group participants to write their daily routines.

Detailed description: People with Multiple Sclerosis (MS) face numerous physical and mental symptoms as well as emotional and social challenges. The fact that the disease usually occurs in young adulthood, when individuals are most productive, causes disability, its unpredictable and variable nature, and the lack of a known treatment make it difficult to live with MS and accept the disease. The physical, cognitive, behavioral and social changes that occur with the disease affect daily life activities, well-being. and greatly affects the quality of life. There are various interventions developed to improve the adaptation processes of individuals diagnosed with a chronic disease such as MS, to prevent and reduce psychiatric symptoms, and to increase quality of life and well-being. One of the intervention approaches is positive psychological interventions from the field of positive psychology. Positive psychological interventions are a psychosocial intervention method based on the systematic completion of certain activities aimed at increasing positive emotions, thoughts and behaviors. Since the interventions focus on strengthening positive mental states rather than reducing psychological symptoms, they also have an advantage over traditional interventions in that they can be applied to both sick and non-patients. However, it appears that positive psychological intervention studies have just begun to be implemented in patients with MS. In our country, no study has been found using positive psychological intervention in MS patients. This study aims to determine the effectiveness of positive psychological interventions on the quality of life and well-being levels of patients with multiple sclerosis.

Eligibility criteria: Inclusion Criteria:

* Diagnosis of MS by a neurologist according to McDonald criteria
* Having at least 1 year of MS history
* Expanded Disability Status Scale (EDSS) score measured by the neurology clinic is \<3.5
* Being between the ages of 18-65 being literate
* Ability to communicate in Turkish
* Volunteering to participate in the study

Exclusion Criteria:

* Having an MS attack and using corticosteroid medication for the last 3 months
* A score of 21 or less on the Montreal Cognitive Assessment (MoCA) test
* Having a mental or organic disability in communicating
* Being diagnosed with any chronic disease other than MS
* Using psychotropic medication or continuing psychotherapy
* Not having or being able to obtain a phone that can connect to the internet

Primary outcomes:
measure: Multiple Sclerosis Quality of Life Scale (MSQOL)-54
timeFrame: six month
measure: PERMA Measuring Tool
timeFrame: six month
Secondary outcomes:
measure: Positive and Negative Mood Scale (PNDS)
timeFrame: six month
Other outcomes:
Locations:
city: Bolu
country: Turkey
facility: Bolu Abant İzzet Baysal University
Study officials:
affiliation: Bolu Abant İzzet Baysal University
name: Nazmiye Yıldırım
role: STUDY_CHAIR
affiliation: Bolu Abant İzzet Baysal University
name: Aliye Yaşayacak
role: PRINCIPAL_INVESTIGATOR
References: