Clinical trial NCT04352036: Constitution of a Prospective Cohort of Patients With Acute Suppurative Hidrosadenitis Followed in the Great West: the COVER Cohort (Verneuil Cohort)
Official title: Constitution of a Prospective Cohort of Patients With Acute Suppurative Hidrosadenitis Followed in the Great West: the COVER Cohort (Verneuil Cohort)
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Acute Hidrosadenitis
Lead sponsor: Nantes University Hospital
Sponsor class: OTHER
First posted: 2020-04-17
Enrollment: 465
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The population studied will relate to patients consulting or being hospitalized for Acute Hidrosadenitis, whatever its severity.

Brief summary: Our primary objective with this cohort will be to define the different phenotypes of acute hidrosadenitis, the characterization of which is essential to define suitable therapeutic approaches. Indeed, our recent data allow us to note that there would be different phenotypes of acute hidrosadenitis and therefore different pathologies inducing different follow-ups and care.


Eligibility criteria: Inclusion Criteria:

* Patient diagnosed with acute hidrosadenitis by a dermatologist
* Patient agreeing to be part of the study

Exclusion Criteria:

* No affiliation to a social security scheme
* Major under guardianship
* Protected persons

Primary outcomes:
measure: Description of the natural history and identification of the different clinical forms of acute hidrosadenitis
timeFrame: through study completion, an average of 3 years
measure: Prevalence of severe forms (grade II, III)
timeFrame: through study completion, an average of 3 years
measure: Definition of different phenotypes of acute hidrosadenitis
timeFrame: through study completion, an average of 3 years
measure: Identify the environmental factors associated with the chronicity of the disease
timeFrame: through study completion, an average of 3 years
measure: Identify the environmental factors associated with the chronicity of the disease
timeFrame: through study completion, an average of 3 years
measure: Identify the environmental factors associated with the chronicity of the disease
timeFrame: through study completion, an average of 3 years
measure: Identify the environmental factors associated with the chronicity of the disease
timeFrame: through study completion, an average of 3 years
measure: Identify the environmental factors associated with the chronicity of the disease
timeFrame: through study completion, an average of 3 years
measure: Involvement of innate immunity in the development of this chronic inflammation with skin biopsies for bacteriological samples
timeFrame: through study completion, an average of 3 years
measure: Determine the impact of vitamin D deficiency on inflammatory bowel disease
timeFrame: through study completion, an average of 3 years
measure: Determine the impact of IGF1 deficiency on inflammatory bowel disease
timeFrame: through study completion, an average of 3 years
Secondary outcomes:
Other outcomes:
Locations:
city: Angers
country: France
facility: CHU Angers
city: Brest
country: France
facility: Chru Brest
city: La Roche Sur Yon
country: France
facility: CHD Vendée
city: La Rochelle
country: France
facility: CH La Rochelle
city: Le Mans
country: France
facility: CH
city: Lorient
country: France
facility: CH bretagne sud
city: Nantes
country: France
facility: CHU de Nantes - Dermatologie
city: Orléans
country: France
facility: Chr D'Orléans
city: Poitiers
country: France
facility: CHU Milétrie
city: Quimper
country: France
facility: Ch de Cornouaille
city: Rennes
country: France
facility: CHU Pontchaillou
city: Saint-Brieuc
country: France
facility: Ch Saint-Brieuc
city: Tours
country: France
facility: CHRU Tours
Study officials:
References: