Clinical trial NCT04433325: COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units
Official title: COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: COVID-19
Intensive Care Unit Syndrome
Keywords: Medical transport by train
Lead sponsor: Rennes University Hospital
Sponsor class: OTHER
First posted: 2020-06-16
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020

Brief summary: Since early 2020, France knows a sanitary crisis with a massive influx of COVID-19 patients admitted in Intensive Care Units (ICU). It led to a saturation of the French health system, especially in some geographic areas such as East of France or Paris region. Therefore, authorities decided to transfer some critically ill patients from these crowded ICUs to less busy regional ICUs. it was done for the first time by medical train transportation. Knowing that the investigators lack experience regarding this type of medical evacuation, regarding the high number of transferred patients, with such a logistic effort, the investigators decided to study this phase of the COVID-19 sanitary crisis in order to draw a feedback. So far, there are no data in the literature regarding this topic.


Eligibility criteria: Inclusion Criteria:

* Age \> 18 years
* COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020
* Patients (or legal representative) with no opposition to inclusion in medical research protocol
* Regarding case group : Patients transferred from Paris's ICU
* Regarding case control group : Patients admitted in ICU with no transfer from Paris

Exclusion Criteria:

- \> 18 years under legal protection and patients with liberty restriction

Primary outcomes:
measure: number of death
timeFrame: at Intensive Care Units discharge, an average of 1 months
Secondary outcomes:
measure: number of infections
timeFrame: from date of admission until Intensive Care Units discharge, assessed up to 1 months
measure: number of days of mechanical ventilation
timeFrame: from date of admission until Intensive Care Units discharge, assessed up to 1 months
measure: number of days of sedation
timeFrame: from date of admission until Intensive Care Units discharge, assessed up to 1 months
measure: number of days of use of neuromuscular blocking agents
timeFrame: from date of admission until Intensive Care Units discharge, assessed up to 1 months
measure: number of days of vasopressor use
timeFrame: from date of admission until Intensive Care Units discharge, assessed up to 1 months
measure: number of days in Intensive Care Units
timeFrame: from date of admission until Intensive Care Units discharge, assessed up to 1 months
measure: number of days in hospital
timeFrame: from date of admission until hospital discharge, assessed up to 1 months
Other outcomes:
Locations:
city: Poitiers
country: France
facility: CHU Poitiers
city: Tours
country: France
facility: CHU Tours
Study officials:
affiliation: CHU Rennes
name: Benoît Painvin
role: PRINCIPAL_INVESTIGATOR
References: