Clinical trial NCT01169922: HIV Prevention With Adolescents: Neurocognitive Deficits and Treatment Response
Study type: INTERVENTIONAL
Overall status: WITHDRAWN
Phase: NA
Conditions: Risk Reduction Behavior
Sexual Behavior
Health Behavior
Drinking Behavior
Adolescent Behavior
Lead sponsor: University of New Mexico
Sponsor class: OTHER
Collaborators: name: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
First posted: 2010-07-26
Enrollment: 0
Sex: ALL
Minimum age (years): 14
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: TREATMENT

Brief summary: This research is examining how genetic and brain factors play a role in adolescents' health risk behavior as well as studying behaviors that young people engage in that may place them at risk for contracting a sexually transmitted disease like HIV/AIDS, and what kind of educational program works best to reduce these risky behaviors.

Detailed description: A baseline assessment is conducted, including a computer questionnaire assessing personality characteristics, attitudes toward and experiences with sex, alcohol, drugs, and cigarettes, among other things. The participant also meets with a therapist to conduct a brief motivational interview at this time. A "Time-Line Follow-Back" is conducted; this notes incidences of sexual intercourse, alcohol use, marijuana use, and cigarette use in a 30-day period. An fMRI is conducted, and a saliva sample is gathered. During the second session of the study, participants are randomly assigned to either a sex and alcohol risk reduction intervention, or a sex risk reduction intervention. After the intervention, participants are contacted at 3 month intervals (3 months later, 6 months later, 9 months later, and 12 months later) to meet. At these "follow-up" meetings, another Time-Line Follow-Back is conducted, along with another computer questionnaire (again assessing attitudes toward and experiences with sex, alcohol, drugs, and cigarettes).

Eligibility criteria: Inclusion Criteria:

* Adolescents age 14-18
* Involved in Juvenile Justice System OR enrolled in a private school

Exclusion Criteria:

* Currently taking anti-psychotics
* Involved in similar intervention-based study (2 similar studies being conducted simultaneously by this lab)

Primary outcomes:
measure: Time-Line Follow-Back (TLFB)
timeFrame: 3-months post-intervention
measure: Time-Line Follow-Back (TLFB)
timeFrame: 6-months post-intervention
measure: Time-Line Follow-Back (TLFB)
timeFrame: 9-months post-intervention
measure: Time-Line Follow-Back (TLFB)
timeFrame: 12-months post-intervention
Secondary outcomes:
measure: Computer questionnaire
timeFrame: 3 months post-intervention
measure: Computer questionnaire
timeFrame: 6 months post-intervention
measure: Computer questionnaire
timeFrame: 9 months post-intervention
measure: Computer questionnaire
timeFrame: 12 months post-intervention
Other outcomes:
Locations:
city: Albuquerque
country: United States
facility: Diversion Meetings (Youth Services Center)
state: New Mexico
city: Albuquerque
country: United States
facility: Youth Reporting Center (Youth Services Center)
state: New Mexico
city: Albuquerque
country: United States
facility: Albuquerque Academy
state: New Mexico
city: Albuquerque
country: United States
facility: Sandia Preparatory School
state: New Mexico
Study officials:
name: Angela D Bryan, PhD
role: PRINCIPAL_INVESTIGATOR
References: