Clinical trial NCT03920020: Comparison of The Effects of Concentric And Eccentric Isokinetic Exercises in Patients With Knee Osteoarthritis
Official title: Comparison of The Effects of Concentric and Eccentric Isokinetic Exercises on Proprioception and Muscle Architecture in Patients With Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Concentric
Eccentric
Muscle Architecture
Proprioception
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2019-04-18
Enrollment: 43
Sex: ALL
Minimum age (years): 45
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in 42 patients with knee osteoarthritis enrolled the study.

Detailed description: This study aims to compare the effects of concentric and eccentric isokinetic exercises on proprioception and muscle architecture in patients with knee osteoarthritis. 42 patients will be included in this study. Patients will be divided into three groups; concentric exercise group (n:14), eccentric exercise group (n:14) and control group (n:14). A conventional physiotherapy program and a standard therapeutic exercise program will be applied to all subjects. In addition to these exercise and physiotherapy programme, concentric and eccentric exercise groups will perform the exercises related to their groups. All three groups will participate in this program for a total of 18 sessions 3 times a week for 6 weeks. All groups will be subject to re-evaluation after 6 weeks.

Eligibility criteria: Inclusion Criteria:

* Diagnosis of primary knee osteoarthritis according to American College of Radiology
* Being radiographically K-L grade 2-3
* Presence of symptoms for at least 3 months
* Patients who have been planned a conventional physiotherapy programme because of knee osteoarthritis
* Presence of functional capacity for outpatient physical therapy

Exclusion Criteria:

* Patients with seconder knee osteoarthritis
* History of lower extremity or spine surgery
* History of intraarticular injection in last 1 month
* Patients with neurological disease that will affect muscle strength, balance and coordination

Primary outcomes:
measure: Joint position sense
timeFrame: 6 weeks
measure: Ultrasonographic assessment of quadriceps and hamstring muscles
timeFrame: 6 weeks
Secondary outcomes:
measure: WOMAC (Western Ontario & McMaster Universities Osteoarthritis Index)
timeFrame: 6 weeks
measure: Range of motion
timeFrame: 6 weeks
measure: Muscle strength assessment
timeFrame: 6 weeks
measure: Shortness of muscles assessment
timeFrame: 6 weeks
measure: Pain assessment: VAS (Visual analog scale)
timeFrame: 6 weeks
measure: Balance assessment
timeFrame: 6 weeks
measure: The timed up and go test
timeFrame: 6 weeks
measure: Sit to stand test
timeFrame: 6 weeks
measure: Timed 10 meter walk test
timeFrame: 6 weeks
measure: Short Form 12 (SF-12) health survey
timeFrame: 6 weeks
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Institute of Health Sciences
state: Altındağ
Study officials:
affiliation: Hacettepe University
name: Aysun Baki, phd student
role: PRINCIPAL_INVESTIGATOR
References: