Clinical trial NCT05113524: Effects of Dance on the Turning Characteristics of Patients With Parkinson's Disease
Official title: The Effects of Dance on the Turning Characteristics of Patients With Parkinson's Disease During the Timed up and Go Test
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease(PD)
Keywords: Dance
Functional Mobility
Turning
Lead sponsor: Federal University of Rio Grande do Sul
Sponsor class: OTHER
Collaborators: name: University of Wolverhampton
name: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
First posted: 2021-11-09
Enrollment: 15
Sex: ALL
Minimum age (years): 50
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The proposed control intervention trial, aims to analyse the effects of Dance in the turning characteristics in patients with Parkinson Disease (PD) using three- dimensional (3D) analysis during the timed up and go (TUG) test.

Detailed description: Experimental Design: control intervention non-randomized trial. Search Location: University of Wolverhaptom, Walsall Campus, United Kingdom; Federal University of Rio Grande do Sul, Brazil.

Participants: 15 adults aged between 50 and 80 years, with a clinical diagnosis of idiopathic PD, staging between 1 and 4 of the Hoehn \& Yahr Scale, recruited from Dance for Parkinson's Projects, West-Midlands County, United Kingdom, and from Parkinson's UK (United Kingdom).

Interventions: Dance intervention for 3 months, 2 times/week (1 instructor lecture session and 1 home session following a prepared video), 2 hours per week. Controls, not alter their personal lifestyle, but undergo the same testing as the exercise intervention group.

Outcomes: clinical-functional parameters (number of steps and total time of the 180 turning phase of the Timed up and go Test - TUG - and biomechanics parameter - girdle dissociation) Data Analysis: Data will be described by average values and standard deviation values. All statistical analyses will be carried out using SPSS version 23, and Microsoft Excel Program version 16.44. The significance level is set at p\<0.05. The Cohen's d is going to be used to predict effect interpreted as small d= 0.2, medium d=0.5, and large d=0.8, and 95% confidence intervals were presented.

Eligibility criteria: Inclusion Criteria:

* Confirmed diagnosis of PD according to the London Brain Bank Criteria;
* Able to understand the verbal instructions for the tests and to walk;
* Or attempt to walk independently with no walking aid.

Exclusion Criteria:

* Recent surgeries,
* Deep brain stimulation (DBS);
* Severe heart diseases, uncontrolled hypertension, myocardial infarction within a period of less than one year;
* Fitted with a pacemaker;
* Prostheses in the lower limbs;
* Stroke or other associated neurological diseases.

Primary outcomes:
measure: 180 turning phase of the Timed up and go Test (TUG)
timeFrame: Change from baseline at 3 months
Secondary outcomes:
measure: Girdle dissociation
timeFrame: Change from baseline at 3 months
Other outcomes:
Locations:
city: Porto Alegre
country: Brazil
facility: Aline Nogueira Haas
state: RS
city: Walsall
country: United Kingdom
facility: University of Wolverhampton, Walsall Campus
state: West Midlands
Study officials:
affiliation: Federal University of Rio Grande do Sul
name: Aline Nogueira Haas, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Dos Santos Delabary M, Komeroski IG, Monteiro EP, Costa RR, Haas AN. Effects of dance practice on functional mobility, motor symptoms and quality of life in people with Parkinson's disease: a systematic review with meta-analysis. Aging Clin Exp Res. 2018 Jul;30(7):727-735. doi: 10.1007/s40520-017-0836-2. Epub 2017 Oct 4.
citation: Dos Santos Delabary M, Monteiro EP, Donida RG, Wolffenbuttel M, Peyre-Tartaruga LA, Haas AN. Can Samba and Forro Brazilian rhythmic dance be more effective than walking in improving functional mobility and spatiotemporal gait parameters in patients with Parkinson's disease? BMC Neurol. 2020 Aug 18;20(1):305. doi: 10.1186/s12883-020-01878-y.