Clinical trial NCT05379998: Neural Mobilization Versus PNF Hold Relax Technique on Lower Extremity in Hemiplegic Stroke
Official title: Comparison of Neural Mobilization and Proprioceptive Neuromuscular Facilitation Hold Relax Technique on Lower Limb Motor Function in Hemiplegic Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hemiplegic Stroke
Keywords: Neural mobilization
PNF hold relax
stroke
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-05-18
Enrollment: 54
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Several studies about the effects of nerve mobilizations and stretching exercises have been conducted. This study will contribute to describing the long term effects of these techniques on gait, motor function and quality of life in hemiplegic stroke patients and compare the effectiveness of both techniques.

Detailed description: Several studies about the effects of nerve mobilizations and stretching exercises have been conducted. Evidence regarding the comparison of these two techniques is sparse and is based on different clinical experiences and a less number of studies with limited methodological design. There has been no work regarding the long term effects of these two techniques in improving lower limb motor function in Hemiplegic stroke patients. This study will contribute to describing the long term effects of these techniques on gait, motor function and quality of life in hemiplegic stroke patients and compare the effectiveness of both techniques. A total of 54 patients diagnosed with Hemiplegic stroke will be selected for the collection of data according to the inclusion criteria. Patients will be divided into two groups, Group A and Group B. Group A will receive sciatic nerve mobilization (sliding technique) and Group B will receive Proprioceptive neuromuscular mobilization Hold relax technique 3 days a week for 30 mins per day for 6 weeks. Sciatic nerve mobilizations (sliding technique) will be performed for a duration of 1 minute each for 6 such sets with 60 seconds rest period followed by every set. The Hold Relax Technique of Hamstring will be performed with each hold period lasting for 10 seconds followed by a relaxation phase of 10-15 seconds for 10 repetitions. Data will be collected at baseline, after 3weeks and at 6 weeks after intervention from both groups. Gait will be measured using TUG (Timed up and go), Quality of life will be measured using the Urdu version of SS-QOL(stroke-specific quality of life)and lower limb motor function will be measured using fugl Meyer scale(lower extremity)

Eligibility criteria: Inclusion Criteria:

* Patients with subacute to chronic (3-12months) Hemiplegic Stroke.
* Both Genders.
* Age between 20 and 70 years.
* Patients classified as grade 2 and 3 as per the Modified Rankin scale.
* Patients with or without assistive devices.

Exclusion Criteria:

* Patients having cardiac disorders, rheumatic and orthopedic diseases that would impede the performance of the technique.
* Patients who have undergone some surgery recently.
* Patients having cognitive impairments.
* Contractures of the lower limb joints.
* Patients having associated Neurological Pathologies.

Primary outcomes:
measure: Fugl meyer(lower extremity)
timeFrame: baseline
measure: Fugl meyer(lower extremity)
timeFrame: 3 weeks
measure: Fugl meyer(lower extremity)
timeFrame: 6 weeks
measure: Timed up and go (TUG)
timeFrame: baseline
measure: Timed up and go (TUG)
timeFrame: 3 weeks
measure: Timed up and go (TUG)
timeFrame: 6 weeks
measure: Stroke specific quality of life (SS-QOL)
timeFrame: baseline
measure: Stroke specific quality of life (SS-QOL)
timeFrame: 3 weeks
measure: Stroke specific quality of life (SS-QOL)
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Holly Family Hospital
Study officials:
affiliation: Riphah International University
name: Imran Amjad, PhD
role: PRINCIPAL_INVESTIGATOR
References: