Clinical trial NCT02384863: The Evaluation and Management of Patients With Acute Chest Pain in China
Official title: The Evaluation and Management of Patients With Acute Chest Pain in China
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Chest Pain
Acute Coronary Syndrome
Keywords: Chest Pain
Acute Coronary Syndrome
Cardiac
Emergency Department
Cardiac Testing
Healthcare Utilization
Patient Centered Outcomes
Shared Decision Making
Unnecessary hospital admissions
Decision Aid
Lead sponsor: Qilu Hospital of Shandong University
Sponsor class: OTHER
Collaborators: name: National Health and Family Planning Commission, P.R.China
name: West China Hospital
name: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
name: Shanghai Chest Hospital
name: First Affiliated Hospital of Harbin Medical University
name: Second Affiliated Hospital of Xi'an Jiaotong University
name: Henan Provincial People's Hospital
name: Shandong University
First posted: 2015-03-10
Enrollment: 18000
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: consecutive patients attending the emergency department in 7 Chinese grade Ⅲ hospitals

Brief summary: The purpose of this study is to describe the characteristics, evaluation, management and outcomes of acute chest pain, and to provide opportunities for future initiatives to improve the emergency care for patients experiencing acute chest pain in China.


Eligibility criteria: Inclusion Criteria:

* Acute chest pain(pain in the area inferior to the clavicle, superior to the rib arch, and anterior to the bilateral posterior axillary line）;
* Possible Acute Coronary Syndrome;
* Symptoms occurring within last 24 hours;
* Informed consent from patient or next of kin.

Exclusion Criteria:

* Arrhythmia or heart failure not cause by myocardial ischemia;
* Confirmed lung disease without chest pain;
* No onset of symptoms within last 24 hours;
* No written consensus.

Primary outcomes:
measure: in-hospital mortality
timeFrame: During hospital stay,an expected average of 7 days
Secondary outcomes:
measure: Time between symptom onset and hospital admission
timeFrame: Time interval from symptom onset to arrival at the Emergency Department，an expected median of 9 hours
measure: Major adverse cardiac events (MACE)
timeFrame: 1 year
measure: Cost-Effectiveness Analysis
timeFrame: 1 year
Other outcomes:
Locations:
city: Harbin
country: China
facility: First Affiliated Hospital of Harbin Medical University
state: Heilongjiang
city: Zhengzhou
country: China
facility: Henan Provincial Hospital
state: Henan
city: Xi'an
country: China
facility: Second Affiliated Hospital of Xi'an Jiaotong University
state: Shaanxi
city: Jinan
country: China
facility: Qilu Hospital of Shandong University
state: Shandong
city: Shanghai
country: China
facility: Shanghai Chest Hospital
state: Shanghai
city: Shanghai
country: China
facility: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
state: Shanghai
city: Chengdu
country: China
facility: West China Hospital
state: Sichuan
Study officials:
affiliation: Qilu Hospital of Shandong University
name: Yuguo Chen, M.D., Ph.D.
role: STUDY_CHAIR
References: