Clinical trial NCT01570374: Internet-based Treatment of Generalized Anxiety Disorder
Official title: Internet-based Treatment of Generalized Anxiety Disorder
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Generalized Anxiety Disorder
Keywords: Cognitive behavioral therapy
Internet
Anxiety
Generalized anxiety disorder
Lead sponsor: Umeå University
Sponsor class: OTHER
First posted: 2012-04-04
Enrollment: 103
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to determine whether internet-administered cognitive behavior therapy is a feasible treatment for generalized anxiety disorder.


Eligibility criteria: Inclusion Criteria:

* Satisfy DSM-IV criteria for generalized anxiety disorder
* Living in Sweden and being able to read Swedish
* Access to computer with internet connection

Exclusion Criteria:

* Currently receiving other psychological treatment
* Non-stable use of psychoactive medication
* Deemed suicidal
* Deemed to suffer from other psychological disorder, e.g. psychosis, bipolarity etc.

Primary outcomes:
measure: Change from baseline in Penn State Worry Questionnaire (PSWQ)
timeFrame: 24 hours
measure: Change from baseline in Penn State Worry Questionnaire (PSWQ)
timeFrame: 6 months
measure: Change from baseline in Penn State Worry Questionnaire (PSWQ)
timeFrame: 12 months
measure: Change from baseline in Penn State Worry Questionnaire (PSWQ)
timeFrame: 24 months
Secondary outcomes:
measure: Change from baseline in Beck Anxiety Inventory (BAI)
timeFrame: 24 hours
measure: Change from baseline in Beck Anxiety Inventory (BAI)
timeFrame: 6 months
measure: Change from baseline in Beck Anxiety Inventory (BAI)
timeFrame: 12 months
measure: Change from baseline in Beck Anxiety Inventory (BAI)
timeFrame: 24 months
measure: Change from baseline in Quality Of Life Inventory (QOLI)
timeFrame: 24 hours
measure: Change from baseline in Quality Of Life Inventory (QOLI)
timeFrame: 6 months
measure: Change from baseline in Quality Of Life Inventory (QOLI)
timeFrame: 12 months
measure: Change from baseline in Quality Of Life Inventory (QOLI)
timeFrame: 24 months
measure: Change from baseline in Montgomery-Åsberg Depression Rating Scale (MADRS)
timeFrame: 24 hours
measure: Change from baseline in Montgomery-Åsberg Depression Rating Scale (MADRS)
timeFrame: 6 months
measure: Change from baseline in Montgomery-Åsberg Depression Rating Scale (MADRS)
timeFrame: 12 months
measure: Change from baseline in Montgomery-Åsberg Depression Rating Scale (MADRS)
timeFrame: 24 months
measure: Change from baseline in Patient Health Questionnaire (PHQ-9)
timeFrame: Weekly during treatment period
measure: Change from baseline in Patient Health Questionnaire (PHQ-9)
timeFrame: 24 hours
measure: Change from baseline in Patient Health Questionnaire (PHQ-9)
timeFrame: 6 months
measure: Change from baseline in Patient Health Questionnaire (PHQ-9)
timeFrame: 12 months
measure: Change from baseline in Patient Health Questionnaire (PHQ-9)
timeFrame: 24 months
measure: Change from baseline in Generalized Anxiety Disorder-7 (GAD-7)
timeFrame: Weekly during treatment period
measure: Change from baseline in Generalized Anxiety Disorder-7 (GAD-7)
timeFrame: 24 hours
measure: Change from baseline in Generalized Anxiety Disorder-7 (GAD-7)
timeFrame: 6 months
measure: Change from baseline in Generalized Anxiety Disorder-7 (GAD-7)
timeFrame: 12 months
measure: Change from baseline in Generalized Anxiety Disorder-7 (GAD-7)
timeFrame: 24 months
Other outcomes:
Locations:
city: Umeå
country: Sweden
facility: Department of Psychology, Umeå University
state: Västerbotten
Study officials:
affiliation: Department of Psychology, Umeå University
name: Per Carlbring, Professor
role: PRINCIPAL_INVESTIGATOR
References:
citation: Dahlin M, Andersson G, Magnusson K, Johansson T, Sjogren J, Hakansson A, Pettersson M, Kadowaki A, Cuijpers P, Carlbring P. Internet-delivered acceptance-based behaviour therapy for generalized anxiety disorder: A randomized controlled trial. Behav Res Ther. 2016 Feb;77:86-95. doi: 10.1016/j.brat.2015.12.007. Epub 2015 Dec 21.