Clinical trial NCT04717505: Dual Task Performance in Rheumatic Diseases
Official title: Evaluation of Dual Task Performance in Rheumatic Diseases: A Case-Control Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Rheumatic Diseases
Lead sponsor: Afyonkarahisar Health Sciences University
Sponsor class: OTHER
First posted: 2021-01-22
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: For case group: Patients who come to Afyonkarahisar Health Sciences University Hospital Rheumatology Outpatient Clinic for treatment will constitute the case group of the study.

For control group: Healthy individuals working in Afyonkarahisar Health Sciences University will constitute the control group of the study.

Brief summary: Chronic pain is pain that exceeds the duration of the injury or trigger stimulus and lasts for at least three months. Recent studies show that chronic pain has devastating effects on cognitive functions by causing emotional stress, anxiety, and depression.The studies show that chronic pain affects certain cognitive areas. These areas are; processing speed, short-term memory, longterm memory, inhibitory control and working memory. In addition, task-oriented studies show that chronic pain affects not single tasks, but rather dual tasks that require the use of complex cognitive function (executive function). 40-60% of rheumatologic patients do not have sufficient relief in their pain. For this reason, dual task performance may be affected in individuals diagnosed with rheumatological disease, secondary to the impairment of cognition. In the literature, there are only limited studies showing dual-task performance effects in individuals diagnosed with fibromyalgia and osteoarthritis. However, chronic pain is the main health problem that prevents mobility restriction and participation in all rheumatic diseases. In addition, there is no study investigating the dual task performance effect in rheumatic diseases in a comprehensive way. Therefore, the aim of the study is to investigate the effect of rheumatic diseases on dual-task performance by comparing it with the control group.

Detailed description: Pain is an unpleasant sensory or emotional experience associated with actual or potential tissue damage and is classified as acute or chronic. Acute pain is felt for a short time after an injury or harmful stimulus and is considered part of a defense strategy; It points to an active danger to the organism. Chronic pain that exceeds the duration of the injury or trigger stimulus and lasts for at least three months. Recent studies show that chronic pain has devastating effects on cognitive functions by causing emotional stress, anxiety, and depression. Studies show that chronic pain affects certain cognitive areas. These areas are; processing speed, short-term memory, long-term memory, inhibitory control and working memory. In addition, task-oriented studies show that chronic pain affects not simple tasks, but rather dual tasks that require the use of complex cognitive function (executive function).

Task; it is a behavior, skill or ability that needs to be done. The simple (single) task contains only one alert or task. For example, walking. Dual task requires the simultaneous performance of two different tasks that can be measured independently and have different goals. For example, calculating while walking at the same time. In rehabilitation approaches, single or dual task trainings are applied. Among physiotherapy and rehabilitation approaches, single task training consists only of exercises involving motor performance; Dual task trainings can consist of different exercise combinations that require two different tasks to be performed at the same time as motor + motor, cognitive + cognitive or motor + cognitive performances. The clinical benefit of dual task training is that most of the daily living activities are done in dual task conditions.

Chronic pain is a common health problem associated with most rheumatic diseases. It is pain that lasts for at least 3 months and cannot be completely relieved with standard pain medication. 40-60% of rheumatologic patients do not have sufficient relief in their pain. For this reason, dual-task performance may be affected in individuals diagnosed with rheumatological disease, secondary to the impairment of cognition. In the literature, there are only limited studies showing dual-task performance effects in individuals diagnosed with fibromyalgia and osteoarthritis. However, chronic pain is the main health problem that prevents mobility restriction and participation in all rheumatic diseases. In addition, there is no study investigating the dual task performance effect in rheumatic diseases in a comprehensive way. Therefore, the aim of thestudy is to investigate the effect of rheumatic diseases on dual-task performance by comparing it with the control group.

Eligibility criteria: Inclusion Criteria:

* For the case group

  * Having been diagnosed with any rheumatic disease (rheumatoid arthritis, ankylosing spondylitis... etc.) by a rheumatologist.
  * Not having any acute (fracture, surgery, etc.) or chronic disease (cognitive, neurological, etc.) other than rheumatic disease
  * Being in the age range of 18-65.
  * Presence of chronic pain for at least 3 months
  * Pain over 3.4 cm according to the Visual Analogue Scale (having moderate pain).
  * Standardized Mini Mental Test score\> 24
  * At least primary education or literacy
* For control group:

  * Absence of any known acute (fracture, surgery, etc.) or chronic disease (cognitive, neurological, etc.)
  * Being in the age range of 18-65
  * Standardized Mini Mental Test score\> 24
  * Having at least primary education or literacy

Exclusion Criteria:

* Both control and case groups

  * The presence of any problems (physical, cognitive or psychological) that will prevent the evaluations to be applied within the scope of the research
  * Being pregnant

Primary outcomes:
measure: Gait Speed
timeFrame: 10 minutes
measure: Cadence
timeFrame: 10 minutes
measure: Step lengths
timeFrame: 10 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Afyonkarahisar
country: Turkey
facility: Afyonkarahisar Health Science University
Study officials:
affiliation: Afyonkarahisar Health Science University
name: EMEL TAŞVURAN HORATA
role: PRINCIPAL_INVESTIGATOR
References: