Clinical trial NCT05839522: Australian Hepatitis and Risk Survey in Prisons
Official title: Australian Hepatitis and Risk Survey in Prisons
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Hepatitis C
Hepatitis B
HIV Infections
Keywords: Blood-borne viruses
Prisons
Surveillance
Lead sponsor: Kirby Institute
Sponsor class: OTHER_GOV
First posted: 2023-05-03
Enrollment: 2400
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Participants will be recruited from the selected correctional centre(s) in each jurisdiction. All prisoners, including remandees and sentenced prisoners at the selected site(s) will be randomly selected to participate.

Brief summary: The Australian Hepatitis and risk survey in prisons (AusHep) is a national prison-based blood-borne virus (BBV) surveillance study. This biobehavioural survey involves point-of-care testing for hepatitis C (HCV) antibodies and RNA (if antibody positive), hepatitis B surface antigens, hepatitis B surface antibodies, and HIV surface antibodies, and an interview-style survey on prior testing and treatment history and engagement in risk behaviours. The study will recruit approximately 2400 prisoner participants from 25 representative prisons across Australia, annually.


Eligibility criteria: Inclusion Criteria:

* Any remandee or sentenced prisoner who has provided informed consent is eligible to participate in the study.

Exclusion Criteria:

* Individuals who are unable or unwilling to provide consent or abide by the requirements of the study, as assessed by the trained nurses. Some individuals may be considered unable to provide consent or abide by the requirements of the study if they are:

  * Too mentally unwell to provide consent
  * Profoundly intellectually impaired
  * Unable to speak English and comprehend the survey.

Those excluded from participating in the study will be referred to the local prison clinic service for standard of care.

Primary outcomes:
measure: The prevalence of HCV in Australian prisons
timeFrame: 1 Year
measure: The prevalance of HBV in Australian prisons
timeFrame: 1 year
measure: The prevalance of HIV in Australian prisons
timeFrame: 1 year
Secondary outcomes:
measure: The proportion of individuals who are engaged in each step of HBV and HCV care cascades
timeFrame: 1 Year
measure: The prevalence of risk behaviours and harm reduction access
timeFrame: 1 Year
measure: The factors associated with HCV and HBV infection investigated by the bio-behavioural survey.
timeFrame: 1 Year
measure: The factors associated with engaging in each step of HCV and HBV care cascades and HBV vaccination investigated by the bio-behavioural survey.
timeFrame: 1 Year
Other outcomes:
Locations:
city: Hume
country: Australia
facility: Alexander Maconochie Centre
state: Australian Capital Territory
city: Bathurst
country: Australia
facility: Bathurst Correctional Complex
state: New South Wales
city: Berkshire Park
country: Australia
facility: John Morony Correctional Complex
state: New South Wales
city: Cessnock
country: Australia
facility: Cessnock Correctional Centre
state: New South Wales
city: Kempsey
country: Australia
facility: Mid North Coast Correctional Centre
state: New South Wales
city: Nowra
country: Australia
facility: South Coast Correctional Centre
state: New South Wales
city: Silverwater
country: Australia
facility: Silverwater Women's Correctional Centre
state: New South Wales
city: Wuuluman
country: Australia
facility: Wellington Correctional Centre
state: New South Wales
city: Alice Springs
country: Australia
facility: Alice Springs Correctional Centre
state: Northern Territory
city: Howard Springs
country: Australia
facility: Darwin Correctional Centre
state: Northern Territory
city: Ironbark
country: Australia
facility: Borallon Training and Correctional Centre
state: Queensland
city: Ironbark
country: Australia
facility: Brisbane Women's Correctional Centre
state: Queensland
city: Ironbark
country: Australia
facility: Wolston Correctional Centre
state: Queensland
city: Townsville
country: Australia
facility: Townsville Correctional Centre
state: Queensland
city: Murray Bridge
country: Australia
facility: Mobilong Prison
state: South Australia
city: Northfield
country: Australia
facility: Adelaide Women's Prison
state: South Australia
city: Northfield
country: Australia
facility: Yatala Labour Prison
state: South Australia
city: Risdon Vale
country: Australia
facility: Mary Hutchinson Women's Prison
state: Tasmania
city: Risdon Vale
country: Australia
facility: Risdon Maximum Prison
state: Tasmania
city: Risdon Vale
country: Australia
facility: Ron Barwick Minimum Security Prison
state: Tasmania
city: Bunbury
country: Australia
facility: Bunbury Regional Prison
state: Western Australia
city: Casuarina
country: Australia
facility: Casuarina Prison
state: Western Australia
city: Roebourne
country: Australia
facility: Roebourne Regional Prison
state: Western Australia
city: West Swan
country: Australia
facility: Bandyup Women's Prison
state: Western Australia
Study officials:
References: