Clinical trial NCT04325074: Mental Practice and Manipulative Skills Training in Multiple Sclerosis
Official title: Mental Practice and Manipulative Skills Training in Multiple Sclerosis: a Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Multiple Sclerosis
Lead sponsor: Universidad Rey Juan Carlos
Sponsor class: OTHER
First posted: 2020-03-27
Enrollment: 40
Sex: ALL
Minimum age (years): 25
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Introduction: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system which produces both motor and cognitive dysfunctions. MS causes a decline in the performance of activities of daily living (ADL) due to impairments affecting limb function.

Aim: This pilot study sought to determine whether the use of mental practice (MP) or the combined use of MP and the training of manipulative skills would improve the manipulation motor skills and treatment satisfaction among people with MS.

Methods: The study participants were people with MS. Blinded evaluators performed three assessments for each patient (pre-treatment, post-treatment and at a three month follow up). The patients were divided into three groups with alternate allocation: (A) Mental practice, (B) Mental practice + skills training and (C) Control group.

Keywords: activities of daily living; manual dexterity; mental practice, motor image; multiple sclerosis.


Eligibility criteria: Inclusion Criteria:

* patients diagnosed with MS of the RRMS and SPMS subtypes, without the presence of flare-ups during the past three months and aged between 25 and 60 years;
* an Expanded Disability Status Scale (EDSS) score of ≤7,
* not presenting depressive symptoms (measured using the Beck Depression Inventory, BDI),
* not presenting cognitive decline, measured using the Montreal Cognitive Assessment (MoCA) or Minimental Status Examination.
* In addition, they had to be regularly attending physical therapy and/or occupational therapy rehabilitation treatments.

Primary outcomes:
measure: Nine Hole Peg Test (NHPT). Pre-treatment
timeFrame: Pre-treatment assessments were performed with each patient.
measure: Box and Block Test (BBT). Pre-treatment
timeFrame: Pre-treatment assessments were performed with each patient.
measure: The ABILHAND questionnaire. Pre-treatment
timeFrame: Pre-treatment assessments were performed with each patient.
measure: The Canadian Occupational Performance Measure (COPM). Pre-treatment
timeFrame: Pre-treatment assessments were performed with each patient.
Secondary outcomes:
measure: Nine Hole Peg Test (NHPT). Post-treatment
timeFrame: Immediately after treatment assessments were performed with each patient.
measure: Box and Block Test (BBT). Post-treatment
timeFrame: Immediately after treatment assessments were performed with each patient.
measure: The ABILHAND questionnaire. Post-treatment
timeFrame: Immediately after treatment assessments were performed with each patient.
measure: The Canadian Occupational Performance Measure (COPM). Post-treatment
timeFrame: Immediately after treatment assessments were performed with each patient.
Other outcomes:
measure: Nine Hole Peg Test (NHPT). Three-month follow-up
timeFrame: Three-month follow-up assessments were performed with each patient.
measure: Box and Block Test (BBT). Three-month follow-up
timeFrame: Three-month follow-up assessments were performed with each patient.
measure: The ABILHAND questionnaire. Three-month follow-up
timeFrame: Three-month follow-up assessments were performed with each patient.
measure: The Canadian Occupational Performance Measure (COPM). Three-month follow-up
timeFrame: Three-month follow-up assessments were performed with each patient.
Locations:
Study officials:
References: