Clinical trial NCT03411616: Eating Behavior, Food Craving and Relation to Excessive Weight Gain in Patients Submitted to Liver Transplantation
Official title: Eating Behavior, Food Craving and Relation to Excessive Weight Gain in Patients Submitted to Liver Transplantation
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Eating Behavior
Liver Transplant
Keywords: Eating behavior
Excessive weight
Food craving
Liver transplantation
Obesity
Weight gain
Lead sponsor: Federal University of Minas Gerais
Sponsor class: OTHER
Collaborators: name: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
name: Conselho Nacional de Desenvolvimento Científico e Tecnológico
First posted: 2018-01-26
Enrollment: 301
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who undergone liver transplantation at least 18 years of age, who were regularly followed up at the Bias Fortes outpatient clinic

Brief summary: Excessive weight gain, obesity and metabolic syndrome are highly prevalent in patients undergoing liver transplantation. Traditional methods of assessing dietary intake have failed to demonstrate an association between these problems and dietary intake. Patients with an indication for transplantation due to ethanolic cirrhosis, ex-smokers and those with a previous history of overweight were identified as being at greater risk for overweight and metabolic syndrome, and these factors may be related to the change in eating behavior after the operation. Objective: To evaluate the eating behavior, the occurrence of food craving and relation to weight gain, overweight and obesity after liver transplantation. Method: This is a cross-sectional study in which adult and elderly patients in follow-up at the Hepatic Transplant Outpatient Clinic of the Alpha Institute of Gastroenterology of the Federal University of Minas Gerais were evaluated for eating behavior and food craving. The evaluation of the eating behavior was performed with the help of the Three Factor Eating Questionnaire-R21 (TFEQ-R21), translated version and validated for Portuguese. Food Craving Questionnaires State (FCQ-S) and Trait (FCQ-T) and the Brazilian Inventory of Foods Related to Craving (FCI-Br) were used in the translated and validated versions for Portuguese. Demographic, lifestyle, clinical and anthropometric variables of the evaluated patients were obtained through electronic medical records. Weight gain was assessed by the difference between the current weight and the first post-transplant outpatient weight.


Eligibility criteria: Inclusion Criteria:

* Patients who undergone liver transplantation
* At least 18 years of age
* Patients regularly followed up at the Bias Fortes outpatient clinic
* Patients who agreed to participate in the study

Exclusion Criteria:

* Patients who were unable to write and who did not have an accompanying person present as a literate person
* Pregnant or nursing women

Primary outcomes:
measure: Eating behavior
timeFrame: 40 minutes
Secondary outcomes:
measure: Food Craving Questionnaires State (FCQ-S)
timeFrame: 20 minutes
measure: Food Craving Questionnaires Trait (FCQ-T)
timeFrame: 20 minutes
measure: Brazilian Inventory of Foods Related to Craving (FCI-Br)
timeFrame: 20 minutes
Other outcomes:
measure: Demographic, lifestyle, clinical and anthropometric variables
timeFrame: 40 minutes
Locations:
city: Belo Horizonte
country: Brazil
facility: Hospital of Clinics of the University Federal of Minas Gerais
state: Minas Gerais
Study officials:
References: