Clinical trial NCT05578963: Correlation Between Palmaris Longus Muscle and Carpel Tunnel Syndrome
Official title: Corelation Between Palmaris Longus Muscle and Carpel Tunnel Syndrome in Health Profession Students Across Pakistan
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Carpal Tunnel Syndrome
Lead sponsor: Bahria University
Sponsor class: OTHER
First posted: 2022-10-13
Enrollment: 258
Sex: ALL
Minimum age (years): 18
Maximum age (years): 23
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: • Health profession Students with carpel tunnel syndrome across Pakistan

Brief summary: The Palmaris longus (PL) muscle is a long, adaptable muscle that lies between the Flexor Carpi Ulnaris and Flexor Carpi Radialis muscles in the shallow volar segment of the lower arm. It has been acknowledged as a minimal muscle, nonetheless, in light of the fact that reviews have uncovered that around 30% of the populace might be feeling the loss of this muscle in one lower arm (one-sided) or the two lower arms (reciprocal), but the rate could continuously fluctuate. Carpal tunnel syndrome is an often-observed disease that causes pain, numbness, and tingling in the hand and arm. The disease occurs when one of the major nerves to the hand - the median nerve - is compressed as it moves across the wrist. The abnormal passage of palmaris longus tendon through the carpal tunnel leads to a contributory factor for causing the median nerve compression.

Detailed description: The Palmaris longus (PL) muscle is a long, adaptable muscle that lies between the Flexor Carpi Ulnaris and Flexor Carpi Radialis muscles in the shallow volar segment of the lower arm. It has been acknowledged as a minimal muscle, nonetheless, in light of the fact that reviews have uncovered that around 30% of the populace might be feeling the loss of this muscle in one lower arm (one-sided) or the two lower arms (reciprocal), but the rate could continuously fluctuate. Agenesis is a typical physical variety. Hold strength is unaffected by the deficiency of the palmaris longus. Past examination has assessed that 15% of the worldwide populace has palmaris longus ligament agenesis (PLA), which is more successive in ladies and has an affinity to be higher respectively however, if present singularly, is normally on the left side. It emerges from the Medial Epicondyle of the Humerus and goes into the Palmar Aponeurosis and Flexor Retinaculum at the wrist joint through the normal flexor ligament. It accepts its innervation from the Median Nerve. Palmaris longus works couple with the lower arm's long flexors to give flexion at the wrist joint and small joints of the hand. The muscle additionally helps in fixing and worrying the palmar aponeurosis.

Carpal tunnel syndrome is an often-observed disease that causes pain, numbness, and tingling in the hand and arm. The disease occurs when one of the major nerves to the hand - the median nerve - is compressed as it moves across the wrist. The abnormal passage of palmaris longus tendon through the carpal tunnel leads to a contributory factor for causing the median nerve compression. The tendinous structure normally passes anterior to the flexor retinaculum and then distally continues with the palmar aponeurosis. This topographic relationship of the tendon with the median nerve makes its anatomical variations a common cause of median nerve entrapment. Several anatomical variations of the PL muscle have been studied in the past. The variations could be in the form of complete absence, insertion site variation, multiple muscle bellies, different location of the muscle belly, and so on.

Eligibility criteria: Inclusion Criteria:

* Health profession Students with carpel tunnel syndrome across Pakistan
* Age should be 18-23 years

Exclusion Criteria:

* Students who had carpel tunnel release surgery
* Any wrist related pathology
* Involve in any other wrist related research
* Underwent any surgery of wrist
* Underwent any surgery that required replacement of tendon
* Underwent any surgery that had Palmaris longus tendon for replacement

Primary outcomes:
measure: correlation of palmaris longus tendon and carpel tunnel syndrome
timeFrame: 1 day
Secondary outcomes:
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: Seyyada Tahniat Ali
state: Sindh
Study officials:
affiliation: Bahria university health sciences campus
name: Seyyada T Ali
role: PRINCIPAL_INVESTIGATOR
References:
citation: Clinical Assessment of the Palmaris Longus - Accuracy of common tests Authors: Kigera JWM1 MBChB, MMed (Ortho), Mukwaya S2 Affiliation
citation: Priganc VW, Henry SM. The relationship among five common carpal tunnel syndrome tests and the severity of carpal tunnel syndrome. J Hand Ther. 2003 Jul-Sep;16(3):225-36. doi: 10.1016/s0894-1130(03)00038-3.
citation: Mohammad WS. Work-related risk factors for Carpal Tunnel Syndrome among Majmaah University female touchscreen users. Pak J Med Sci. 2019 Sep-Oct;35(5):1221-1226. doi: 10.12669/pjms.35.5.683.