louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT03429725: Increasing Individualism and Collectivism
Official title: Increasing Individualism or Collectivism on Amazon Mechanical Turk Participants
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Individual Difference
Lead sponsor: Yale-NUS College
Sponsor class: OTHER
First posted: 2018-02-12
Enrollment: 495
Sex: ALL
Minimum age (years): 21
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: An online survey is conducted on MTurk populations from India and USA. Participants were assigned either a condition with primes of individualism or one with primes of collectivism, before responding to a scale on culture and indicating details of their demographics.


Eligibility criteria: Inclusion Criteria:

* above age 21

Exclusion Criteria:

* below age 21
* not able to make decisions for self

Primary outcomes:
measure: Higher collectivism or individualism level
timeFrame: 10 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Singapore
country: Singapore
facility: Yale-NUS College
Study officials:
References:
Clinical trial NCT03624725: A Clinical Study of the Effects of Modified BII+Braun on Quality of Life After for Distal Gastric Cancer
Official title: A Single-center, Randomized, Controlled Clinical Study of the Effects of Modified and Traditional BII+Braun Digestive Tract Reconstruction Methods on Quality of Life After Radical Gastrectomy for Distal Gastric Cancer
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Quality of Life
Keywords: Gastric cancer
Quality of life
Lead sponsor: The Third Affiliated Hospital of Harbin Medical University
Sponsor class: OTHER
First posted: 2018-08-10
Enrollment: 592
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The jejunum of the input segment is properly ligated with double line 7 at 3-5cm from the anastomotic site, and the jejunum of the output segment is extended to 30cm

Detailed description: The T1-4a N0-3 M0 gastric adenocarcinoma patients were used to evaluate whether the quality of life after modified BII+Braun digestive tract reconstruction was superior to the traditional BII+Braun digestive tract reconstruction

Eligibility criteria: Inclusion Criteria:

* 18\<age\<75
* Gastric lesions were diagnosed as gastric adenocarcinoma by endoscopic biopsy
* The preoperative clinical stage is T1-4a,N0-3,M0(According to AJCC- 7th TNM tumor stage)
* It is expected that the results of R0 surgery can be obtained by performing distal gastrectomy and D2 lymph node dissection
* Preoperative ECOG performance status score 0/1
* Nutrition risk screening（NRS2002）
* Preoperative ASA score I-III
* Patient informed consent

Exclusion Criteria:

* Pregnancy or breastfeeding women
* Severe mental illness
* History of upper abdominal surgery
* History of gastric surgery (including ESD/EMR for gastric cancer)
* 3 years of history of other malignant diseases；
* Gastric cancer patients who have undergone neoadjuvant treatment or recommend neoadjuvant treatment
* A history of unstable angina or myocardial infarction within 6 months
* History of cerebral infarction or cerebral hemorrhage within 6 months
* There is a history of sustained systemic corticosteroid treatment within 1 month
* Needs simultaneous surgical treatment of other diseases；
* Gastric cancer complications (bleeding, perforation, obstruction) require emergency surgery
* Pulmonary function test FEV\<1 predicted value 50%

Primary outcomes:
measure: Effects of quality of life
timeFrame: The quality of life questionnaire was conducted at six months after surgery.
Secondary outcomes:
Other outcomes:
Locations:
city: Harbin
country: China
facility: Gastrointestinal surgery of the affiated tumor hospital
state: Helongjiang
Study officials:
affiliation: Director of Gastrointestinal surgery
name: Yingwei Xue, doctor
role: STUDY_DIRECTOR
References:
Clinical trial NCT00320125: Effects of Dairy Foods on Adolescent Pregnant Mothers and Their Newborns
Official title: Effects of Dairy Foods on Adolescent Pregnant Mothers and Their Newborns
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Pregnancy
Keywords: Dairy
Calcium
Pregnancy
Fetus
Bone mineralization
Lead sponsor: University of Utah
Sponsor class: OTHER
Collaborators: name: National Dairy Council, Rosemont, Illinois, USA
First posted: 2006-05-03
Enrollment: 72
Sex: FEMALE
Minimum age (years): 15
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purpose of the study is to evaluate the effects of different dietary calcium have on the pregnant teen mother and her newborn. We hypothesize that the higher calcium intake during pregnancy will result in higher bone mass in the newborn.

Detailed description: Osteoporosis in the adult remains a significant public health problem. One of the major causes of osteoporosis is the inadequate calcium intake during the pediatric age range of birth to 20 years of age. We believe that this low calcium may start at birth since the fetus is actively accumulating calcium during the last trimester of pregnancy. Adolescents generally have poor calcium intake. Our study is to compare the newborn bone mass from adolescent mothers who are taking the recommended calcium intake from dairy foods or non-dairy foods such as orange juice during pregnancy.

Eligibility criteria: Inclusion Criteria:

* Pregnant mothers aged 15 to 18 years, term gestation

Exclusion Criteria:

* Chronic disease such as hypertension, diabetes, medications that will affect calcium metabolism

Primary outcomes:
measure: Newborn bone mass
measure: Maternal dietary intakes
Secondary outcomes:
measure: Newborn body weight
measure: Maternal blood pressure
measure: Newborn blood for calcium, phosphate, vitamin D
Other outcomes:
Locations:
city: Salt Lake City
country: United States
facility: University Hospital
state: Utah
Study officials:
affiliation: University of Utah
name: Gary M Chan, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Thomas M, Weisman SM. Calcium supplementation during pregnancy and lactation: effects on the mother and the fetus. Am J Obstet Gynecol. 2006 Apr;194(4):937-45. doi: 10.1016/j.ajog.2005.05.032.
citation: Koo WW, Walters JC, Esterlitz J, Levine RJ, Bush AJ, Sibai B. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol. 1999 Oct;94(4):577-82. doi: 10.1016/s0029-7844(99)00371-3.
citation: Merrilees MJ, Smart EJ, Gilchrist NL, Frampton C, Turner JG, Hooke E, March RL, Maguire P. Effects of diary food supplements on bone mineral density in teenage girls. Eur J Nutr. 2000 Dec;39(6):256-62. doi: 10.1007/s003940070004.
citation: Chan GM, McElligott K, McNaught T, Gill G. Effects of dietary calcium intervention on adolescent mothers and newborns: A randomized controlled trial. Obstet Gynecol. 2006 Sep;108(3 Pt 1):565-71. doi: 10.1097/01.AOG.0000231721.42823.9e.
Clinical trial NCT06926725: Effect of High Intensity Interval Training and Ultrasound Cavitation on Lipid Profile in Type 2 Diabetes Patients
Official title: Combined Effect of High Intensity Interval Training and Ultrasound Cavitation on Lipid Profile in Type 2 Diabetes Patients With Abdominal Obesity
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Diabetes Mellitus Type 2
Lead sponsor: Beni-Suef University
Sponsor class: OTHER
First posted: 2025-04-15
Enrollment: 66
Sex: ALL
Minimum age (years): 30
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Type two diabetic patients with abdominal obesity , randomly assigned into 3 equal groups: 66 patients

1. study group (A) 22 patients : They will receive ultrasound cavitation , HIIT and diatery advice .
2. study group (B) 22 patients : They will receive HIIT and diatery advice .
3. control group 22 patients They will only receive diatery advice.
Primary purpose: TREATMENT

Brief summary: The study aim to find out the combined effect of high intensity interval training and ultrasound cavitation on lipid profile in type two diabetic patient with abdominal obesity.

Detailed description: study aim to find out the combined effect of high intensity interval training and ultrasound cavitation on lipid profile in type two diabetic patient with abdominal obesity.Type two diabetic patients with abdominal obesity , randomly assigned into 3 equal groups: 66 patients

1. study group (A) 22 patients : They will receive ultrasound cavitation , HIIT and diatery advice .
2. study group (B) 22 patients : They will receive HIIT and diatery advice .
3. control group 22 patients They will only receive diatery advice.

Eligibility criteria: Inclusion Criteria:

* patient with type 2 diabetes.
* waist circumference \>102 cm in male ,\>88 cm in female
* lipid profile range will be (between border line and high risk ).

Exclusion criteria:

Kidney disease Heart disease Lung disease ,Liver disease ,Neurological disorders ,Pregnant women , breast feeding, immune deficiency , cancer Heavy smoker

Exclusion Criteria:

-

Primary outcomes:
measure: Anthropometric Measurements
timeFrame: 3 months
measure: Lipid profile
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Beni-Suif University Hospital
state: Cairo
Study officials:
References:
citation: Birendra Kumar Jha, Raman Mishra, Jitendra Kumar Singh, Satyam Prakash, & Kamlesh Kumar Yadav. (2024). Assessment of glycemic control and correlation of HbA1c level with lipid profile and duration of diabetes in type 2 diabetes mellitus patients. Janaki Medical College Journal of Medical Science, 12(02), 13-24. https://doi.org/10.3126/jmcjms.v12i02.68365
Clinical trial NCT03691025: Association of the Optic Nerve Sheath Diameter With Eyeball Transverse Diameter in Robot-assisted Prostatectomy
Official title: Ultrasonographic Measurement of the Optic Nerve Sheath Diameter and Its Association With Eyeball Transverse Diameter in Robot-assisted Laparoscopic Radical Prostatectomy
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Elevated Intracranial Pressure
Optic Nerve Sheath Diameter
ONSD /ETD Ratio
Keywords: robot assisted laparoscopic prostatectomy
optic nerve sheath diameter
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2018-10-01
Enrollment: 60
Sex: MALE
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients referred to Hacettepe University Department of Urology

Brief summary: Robot-assisted laparoscopic radical prostatectomy (RALRP) is becoming a popular procedure due to its unique advantages.

Despite these advantages, pneumoperitoneum and steep trendelenburg position are associated with hemodynamic instability and elevated intracranial pressures (ICP).

Ultrasonographic measurement of optic nerve sheath diameter (ONSD) is an indirect but also a generally accepted reliable and noninvasive measurement of elevated ICP. However, optimal cut-off values are highly inconsistent due to multiple factors (gender, height, weight). To eliminate the effects of these factors on the results; a ratio should be established in patients known to have elevated ICPs.

In a recent study ONSD/ eyeball transverse diameter(ETD) in healthy volunteers in a specific population was established.

60 patients without any history of ICP undergoing RALRP will be enrolled to the study. Ultrasonographic measurement of ONSD and ETD will be performed 10 minutes after induction of general anesthesia, 10 minutes after CO2 pneumoperitoneum with trendelenburg positioning and measurements will be repeated hourly and at last after returning to supine position without CO2 pneumoperitoneum at the end of the procedure.

Hemodynamic variables and BIS values on this specific times will be recorded and an arterial sample will be obtained.


Eligibility criteria: Inclusion Criteria:

* 19-75 years patients undergoing RALP

Exclusion Criteria:

* a history of corneal surgery, open-angle or closed-angle glaucoma
* intraocular surgery
* history of elevated ICPs

Primary outcomes:
measure: Association of the Optic Nerve Sheath Diameter With Eyeball Transverse Diameter in Robot-assisted Prostatectomy
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Hacettepe University Department of Anesthesiology and Reanimation
name: Başak Akça
role: PRINCIPAL_INVESTIGATOR
References:
citation: Kim DH, Jun JS, Kim R. Ultrasonographic measurement of the optic nerve sheath diameter and its association with eyeball transverse diameter in 585 healthy volunteers. Sci Rep. 2017 Nov 21;7(1):15906. doi: 10.1038/s41598-017-16173-z.
Clinical trial NCT05483725: Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.
Official title: Assessment of Association Between 3rd Dose of mRNA Vaccine and Risk of SARS-CoV-2 Infection in Kidney Transplant Recipients, Safety and Immunogenicity Assessment.
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Kidney Diseases
Kidney Transplant; Complications
COVID-19
Vaccine Adverse Reaction
Rejection Acute Renal
Rejection Chronic Renal
Keywords: kidney transplantation
COVID-19
mRNA vaccine
vaccine safety
alloreactivity
Lead sponsor: Institute for Clinical and Experimental Medicine
Sponsor class: OTHER_GOV
First posted: 2022-08-02
Enrollment: 108
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Kidney transplant recipients, vaccinated with 2 doses of mRNA vaccines against COVID, scheduled for the first booster dose.

Brief summary: Prospective observational trial to assess immunological safety (anti-HLA antibodies, donor-derived cell-free DNA) and immunological effectiveness (anti-SARS-CoV-2 IgG) of the first booster dose of SARS-CoV-2 mRNA vaccines in kidney transplant recipients at least one year from transplantation.


Eligibility criteria: Inclusion Criteria:

* Kidney transplant recipients followed at Institute for Clinical and Experimental Medicine (IKEM)
* vaccinated with 2 doses of mRNA vaccine (BNT-162b2 or mRNA-1273)
* immunosuppressive regimen includes or does not include mycophenolic acid or mycophenolate mofetil
* COVID naive

Exclusion Criteria:

* age \< 18 years
* pregnant women, breastfeeding women
* unable/unwilling to give informed consent

Primary outcomes:
measure: Immunological safety - anti-HLA antibodies
timeFrame: Comparison of anti-HLA single antigen bead assays at booster dose and three months later.
measure: Immunological safety - donor-derived cell-free DNA
timeFrame: Comparison of dd-cfDNA assays at booster dose and three months later.
Secondary outcomes:
measure: Immunological effectiveness - anti-SARS-CoV-2 antibodies
timeFrame: Comparison of anti-SARS-CoV-2 IgG assays at booster dose and three months later.
Other outcomes:
Locations:
city: Praha
country: Czechia
facility: Institute for Clinical and Experimental Medicine
Study officials:
affiliation: Head of Department of Nephrology
name: Ondrej Viklicky, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00779025: A Safety Evaluation of Personal Lubricant Product When Used by Couples in Home-use Conditions
Official title: A Safety Evaluation of Personal Lubricant Product When Used by Couples in Home-use Conditions
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Coitus
Lead sponsor: Johnson & Johnson Consumer and Personal Products Worldwide
Sponsor class: INDUSTRY
First posted: 2008-10-24
Enrollment: 82
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL

Brief summary: The purpose of this study is to study in couples and to evaluate the safety of personal lubricant products.

Detailed description: Study to evaluate the safety of Class II personal lubricant devices.

Eligibility criteria: Inclusion Criteria:

* Normal, healthy males and females \>18 years of age
* In committed heterosexual relationship for \>6months
* On acceptable method of birth control

Exclusion Criteria:

* Pregnant or breastfeeding
* Allergy to product ingredients
* Irritation or infection in genital area
* Unstable or uncontrolled medical condition

Primary outcomes:
measure: Number of Participants Showing Change From Baseline in Irritation Scores
timeFrame: 1 week
Secondary outcomes:
measure: Number of Sensations Experienced by Male Subjects - Overall
timeFrame: 1 Week
measure: Number of Sensations Experienced by Female Subjects - Overall
timeFrame: 1 Week
Other outcomes:
Locations:
city: Indianapolis
country: United States
facility: Concentrics Center for Research
state: Indiana
Study officials:
affiliation: J&J CPPW
name: Rita Wanser
role: STUDY_DIRECTOR
References:
Clinical trial NCT03935425: FitMi Plus Home Therapy for Stroke Patients
Official title: FitMi Plus: Smart Functional Modules for Practicing Activities of Daily Living After Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cerebral Stroke
Lead sponsor: Flint Rehabilitation Devices, LLC
Sponsor class: INDUSTRY
Collaborators: name: University of California, Irvine
name: Rancho Research Institute, Inc.
First posted: 2019-05-02
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The investigators will investigate the efficacy of a newly developed functional exercise device (FitMi Plus) for people in the chronic stage after a stroke compared to the FitMi Basic (i.e. without functional exercises). FitMi Plus combines objects commonly used during activities of daily living with sensors that can track and record the patient's direction and degree of movement as they perform specific functional tasks described on a computer.


Eligibility criteria: Inclusion Criteria:

* Experienced 1 or more strokes \>6 months prior to enrollment
* Upper Extremity Fugl-Meyer Score \>=15 and \<=55 out of 66
* Absence of moderate to severe upper extremity pain (\<= 4 out of 10 on the visual-analog pain scale)
* Ability to understand the instructions to operate FitMi products

Exclusion Criteria:

* Lack of concurrent severe medical problems
* Lack of visual deficits
* Lack of severe neglect or apraxia
* No concurrent enrollment in another therapy study

Primary outcomes:
measure: Change in Motor Activity Log
timeFrame: Baseline and One-Month Post-Treatment, at seven weeks
Secondary outcomes:
measure: Change in Upper Extremity Fugl-Meyer
timeFrame: Baseline and One-Month Post-Treatment, at seven weeks
Other outcomes:
Locations:
city: Downey
country: United States
facility: Rancho Research Institute, Inc
state: California
city: Irvine
country: United States
facility: Human Neuroperformance Laboratory at University of California Irvine
state: California
Study officials:
affiliation: University of California, Irvine
name: David Reinkensmeyer, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Rancho Research Institute, Inc.
name: Susan Shaw, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04646525: The Relationship Between Covid-19 Infection in Pediatric Patients and Secondary Lymphoid Organs
Official title: The Relationship Between Mild Covid-19 Infection in Pediatric Patients and Protection of Secondary Lymphoid Organs
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Covid19
Immune Deficiency
Tonsillitis
Tonsil Hypertrophy
Adenoiditis
Adenoid Hypertrophy
Keywords: pediatric
covid19
İmmune system
Lead sponsor: Selcuk University
Sponsor class: OTHER
First posted: 2020-11-30
Enrollment: 300
Sex: ALL
Minimum age (years): 1
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Pediatric patients between the ages of 1-16 diagnosed with Covid-19 will be examined by the ENT doctor in terms of tonsil and adenoid tissues after they overcome the active infection period and PCR tests turn negative.

Brief summary: We aimed to find out whether the tonsils and nasal tissues of pediatric patients are the main factors that protects the children's immune system against COVID-19 infection.

Detailed description: Since it is known that the tonsil and adenoid tissues that are known as a secondary lymphoid organ, which form the first line of defense, are more active in childhood than adults, especially in the childhood age group, and since it has been scientifically shown that patients diagnosed with COVID-19 infection in the pediatric age group overcome this disease lightly than adults, we aimed to reveal whether the defined tonsil and adenoid tissues are the main factors that protect the children's immune system against COVID-19 infection.

Eligibility criteria: Inclusion Criteria:

* Patients with COVID-19 infection.
* Patients aged between 1-16 years
* Patients whose PCR test becomes negative

Exclusion Criteria:

* Patients with lymphoid tissue malignant disease
* Patients with known lung disease
* Patients with known systemic disease

Primary outcomes:
measure: The primary outcome of our study was the evaluation of pediatric patients diagnosed with COVID-19 and who had COVID-19 infection in terms of adenoid and tonsillar tissue hypertrophy and the presence of chronic or recurrent infection.
timeFrame: 2020-2021
Secondary outcomes:
Other outcomes:
Locations:
city: Konya
country: Turkey
facility: Selcuk University
state: Selcuklu
Study officials:
affiliation: Selcuk University
name: Merih Onal, Assist. Prof.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Brodin P. Why is COVID-19 so mild in children? Acta Paediatr. 2020 Jun;109(6):1082-1083. doi: 10.1111/apa.15271. Epub 2020 Apr 15. No abstract available.
citation: Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, Tong S. Epidemiology of COVID-19 Among Children in China. Pediatrics. 2020 Jun;145(6):e20200702. doi: 10.1542/peds.2020-0702. Epub 2020 Mar 16.