Clinical trial NCT03003598: The Effects of Intubation Via McGrath Videolaryngoscope on Intraocular Pressure
Official title: The Effects of Endotracheal Intubation Via McGrath Videolaryngoscope on Intraocular Pressure
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Intraocular Pressure
Keywords: Intraocular pressure
videolaryngoscope
direct laryngoscope
Lead sponsor: Inonu University
Sponsor class: OTHER
First posted: 2016-12-28
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: In this study, the investigators aimed to compare the effects of endotracheal intubation via direct laryngoscope (DLS) and McGrath Videolaryngoscope (VL) on intraocular pressure.

Detailed description: Total of 50 American Society of Anesthesiologist Grade 1-2, Mallampati score 1 or 2, age between 18 to 65 patient planned to undergo nonopthalmic surgery will be included to study. Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, American Society of Anesthesiologist Grade III and IV, Body mass index more than 35, difficult intubation, undergo obstetrical surgery and propofol, fentanyl, rocuronium contraindicated will be excluded from the study. Patients will be divided randomly into 2 groups as direct laryngoscopic and videolaryngoscopic intubation group. Patients will be preoxygenated with %100 O2 for 3 minutes then anesthesia will be induced using propofol 2 mg / kg, fentanyl 1 mcg/kg, and rocuronium 0,5 mg / kg in both groups. After 3 minutes mask ventilation, patients will be intubated (women with No:7-7,5, men with No:8-8,5 intubation tube) by oral route. systolic blood pressure, diastolic blood pressure, mean arterial pressure, peripheral oxygen saturation, perfusion indexwill be recorded and intraocular pressure measured by ophthalmologist by tonopen device will be recorded pre-induction (basal), after induction, 1,2,3,5 minutes after intubation, respectively. Period between handling of laryngoscope or videolaryngoscope after termination of mask ventilation and obtain end tidal carbon dioxide will be accepted as application time and recorded. Study will be terminated after 5th minute values taken.

Eligibility criteria: Inclusion Criteria:

* ASA (American Society of Anesthesiologist) Grade 1-2,
* Mallampati score 1 or 2,
* Age between 18 to 65,
* Patient planned to undergo nonopthalmic surgery

Exclusion Criteria:

* Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, ASA Grade III and IV, BMI more than 35,
* Patients with difficult intubation,
* Patients undergoing obstetrical surgery and propofol, fentanyl, rocuronium contraindicated

Primary outcomes:
measure: Systolic blood pressure
timeFrame: From Beginning of Anesthesia induction to 5th minutes of intubation
measure: Heart rate
timeFrame: From Beginning of Anesthesia induction to 5th minutes of intubation
measure: Intraocular pressure
timeFrame: From Beginning of Anesthesia induction to 5th minutes of intubation
measure: Adverse events
timeFrame: within the first 24 hour after surgery
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References: