Clinical trial NCT06040333: Dynamic Neuromuscular Stabilization Training in Dysfunctional Voiding
Official title: The Effect of Dynamic Neuromuscular Stabilization Training in Dysfunctional Voiding : A Randomized Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dysfunctional Voiding
Keywords: dysfunctional voiding
dynamic neuromuscular stabilization exercise
Lead sponsor: Halic University
Sponsor class: OTHER
First posted: 2023-09-15
Enrollment: 34
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: In this study, the effect of dynamic neuromuscular stabilization (DNS) exercise on urinary flow and quality of life in individuals with dysfunctional voiding was investigated. The 34 participants included in the study were randomized into two groups: the experiment in which DNS exercises were applied and the standard therapy group in which the manual application was applied. Uroflowmetry, Voiding Symptom Score (DVSS), Short Form-36 Quality of Life Assessment Short Form were applied to all participants at baseline and at week 6.

Detailed description: In this study, the effect of dynamic neuromuscular stabilization (DNS) exercise on urinary flow and quality of life in individuals with dysfunctional voiding was investigated. This experimental study was conducted with patients who applied to UroKlinik in Istanbul between March 2021 and June 2023 and were diagnosed with dysfunctional voiding. The 34 participants included in the study were randomized into two groups: the experiment in which DNS exercises were applied and the standard therapy group in which the manual application was applied. Voiding Symptom Score (DVSS), Short Form-36 Quality of Life Assessment Short Form and Uroflowmetry test were applied to all participants before and at week 6.

Eligibility criteria: Inclusion Criteria:

* Having been diagnosed with dysfunctional voiding,
* Being between the ages of 18-75,
* Not having a neurogenic bladder
* Not having a urinary tract infection
* Not having an obstacle to exercise,
* Accepting and signing the Approval Form,
* Not having undergone surgery in the last 6 months,

Exclusion Criteria:

* Not being cooperative
* Not being able to participate in the treatment,
* The use of drugs that will affect urination

Primary outcomes:
measure: Uroflowmetry - Maximum flow rate (Qmax)
timeFrame: at the baseline and at week 6.
measure: Uroflowmetry - Average flow rate (Qave)
timeFrame: at the baseline and at week 6.
measure: Uroflowmetry - Corrected maximum flow rate (cQmax)
timeFrame: at the baseline and at week 6.
measure: Uroflowmetry - Flow time (FT)
timeFrame: at the baseline and at week 6.
measure: Uroflowmetry - Voiding volume (VV)
timeFrame: at the baseline and at week 6.
measure: Uroflowmetry - Residual urine (RU)
timeFrame: at the baseline and at week 6.
measure: Dysfunctional Voiding and Incontinence Symptom Score
timeFrame: at the baseline and at week 6.
measure: Short Form 36
timeFrame: at the baseline and at week 6.
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Haliç University
Study officials:
affiliation: Haliç University
name: Seda Saka, PhD
role: STUDY_DIRECTOR
References:
citation: Akbal C, Genc Y, Burgu B, Ozden E, Tekgul S. Dysfunctional voiding and incontinence scoring system: quantitative evaluation of incontinence symptoms in pediatric population. J Urol. 2005 Mar;173(3):969-73. doi: 10.1097/01.ju.0000152183.91888.f6.
citation: Altunkol A, Abat D, Sener NC, Gulum M, Ciftci H, Savas M, Yeni E. Is urotherapy alone as effective as a combination of urotherapy and biofeedback in children with dysfunctional voiding? Int Braz J Urol. 2018 Sep-Oct;44(5):987-995. doi: 10.1590/S1677-5538.IBJU.2018.0194.
citation: Austin PF, Bauer SB, Bower W, Chase J, Franco I, Hoebeke P, Rittig S, Walle JV, von Gontard A, Wright A, Yang SS, Neveus T. The standardization of terminology of lower urinary tract function in children and adolescents: Update report from the standardization committee of the International Children's Continence Society. Neurourol Urodyn. 2016 Apr;35(4):471-81. doi: 10.1002/nau.22751. Epub 2015 Mar 14.
citation: Haylen BT, Ashby D, Sutherst JR, Frazer MI, West CR. Maximum and average urine flow rates in normal male and female populations--the Liverpool nomograms. Br J Urol. 1989 Jul;64(1):30-8. doi: 10.1111/j.1464-410x.1989.tb05518.x.
citation: Mahdieh L, Zolaktaf V, Karimi MT. Effects of dynamic neuromuscular stabilization (DNS) training on functional movements. Hum Mov Sci. 2020 Apr;70:102568. doi: 10.1016/j.humov.2019.102568. Epub 2020 Jan 13.
citation: Zivkovic V, Lazovic M, Vlajkovic M, Slavkovic A, Dimitrijevic L, Stankovic I, Vacic N. Diaphragmatic breathing exercises and pelvic floor retraining in children with dysfunctional voiding. Eur J Phys Rehabil Med. 2012 Sep;48(3):413-21. Epub 2012 Jun 5.