Clinical trial NCT03591263: Clinical Outcomes in Patients Referred to Pulmonary Rehabilitation
Official title: Longitudinal Study of Clinical Outcomes in Patients Referred to Pulmonary Rehabilitation
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Chronic Obstructive Pulmonary Disease
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
First posted: 2018-07-19
Enrollment: 1000
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients with chronic respiratory disease: chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis.

Brief summary: Chronic obstructive pulmonary disease is a chronic inflammatory lung disease that causes obstructed airflow from the lung, characterized by chronic cough, dyspnea, and sputum production, which often misunderstood as aging or catching a cold. These symptoms may be progressive over time. To provide better disease management and early detecting, pulmonary rehabilitation is now considered a fundamental component of the integrated disease management of this population. However, few studies have evaluated the beneficial outcomes in patients referred to pulmonary rehabilitation. Therefore, the purpose of this study is to investigate the clinical outcomes in patients referred to pulmonary rehabilitation in National Taiwan University Hospital.


Eligibility criteria: Inclusion criteria:

1. age \> 20 years old
2. patients with chronic respiratory disease diagnosed by physician that referred to pulmonary rehabilitation in National Taiwan University Hospital including, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis, bronchiectasis
3. can cooperate with pulmonary rehabilitation clinic

Exclusion criteria:

1. angina, acute myocardial infarction in the previous one month
2. pregnancy

Primary outcomes:
measure: Functional exercise capacity using the six-minute walk test
timeFrame: The six-minute walk test needs six minute to complete the test
measure: Muscle strength: hand grip
timeFrame: Hand grip of both hands need about three minutes to complete
measure: Lung hygiene
timeFrame: Lung hygiene is evaluated as the frequency of acute exacerbation in the the past one year
measure: Home-based physical activity
timeFrame: Record the home-based physical activities everyday that the subjects have in the past one week that lasting for one year.
measure: Muscle strength: leg press
timeFrame: Maximum leg press measurement needs about four minutes to complete
measure: Heart rate
timeFrame: Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously
measure: Blood pressure
timeFrame: Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously
measure: Perceived dyspnea
timeFrame: It takes less than one minute to evaluate perceived dyspnea.
measure: Oxygen saturation
timeFrame: Hospital-based physical training takes 30 minutes, once a week, and it also takes 30 min to measure continuously
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Physical Therapy Center at National Taiwan University Hospital
Study officials:
affiliation: National Taiwan University
name: Li-Ying Wang, Phd
role: STUDY_CHAIR
References: