Clinical trial NCT05235880: Effects of Virtual Reality Based Games in Rehabilitation of Parkinson's Disease
Official title: Effects of Virtual Reality Based Games on Upper Extremities, Trunk and Cognitive Functions in Parkinson's Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease
Keywords: parkinson disease
physiotherapy
exergames
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2022-02-11
Enrollment: 20
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to investigate the effects of virtual reality based games on upper extremities, trunk and cognitive functions in patients with Parkinson's Disease.


Eligibility criteria: Inclusion Criteria:

* Diagnosed with Parkinson's disease
* 50 years old and over
* Stage 1.5-3 according to the modified Hoehn-Yahr Staging Scale
* Mini mental test score of 24 and above

Exclusion Criteria:

* Additional neurological disease or symptom other than Parkinson's disease
* Orthopedic disorder that will prevent them from doing exercises
* Severe mental disorders

Primary outcomes:
measure: Upper extremities performance with 9 hole peg test
timeFrame: Change from Baseline at 8 weeks
measure: Upper extremities performance with Minnesota Manual Dexterity Test
timeFrame: Change from Baseline at 8 weeks
measure: Cognitive Status with Montreal Cognitive Assessment
timeFrame: Change from Baseline at 8 weeks
measure: Trunk Functions with Trunk Impairment Scale
timeFrame: Change from Baseline at 8 weeks
Secondary outcomes:
measure: Dynamic balance with functional reach test
timeFrame: Change from Baseline at 8 weeks
measure: Balance and mobility with Timed Up and Go Test
timeFrame: Change from Baseline at 8 weeks
measure: Quality of life with Parkinson's Disease Questionnaire
timeFrame: Change from Baseline at 8 weeks
measure: Disease severity and symptoms with Unified Parkinson Disease Rating Scale Part 2 and 3
timeFrame: Change from Baseline at 8 weeks
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
Study officials:
affiliation: Hacettepe University
name: Gül Yalçın Çakmaklı, Assoc. Prof.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Kalia LV, Lang AE. Parkinson's disease. Lancet. 2015 Aug 29;386(9996):896-912. doi: 10.1016/S0140-6736(14)61393-3. Epub 2015 Apr 19.
citation: Jankovic J. Parkinson's disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry. 2008 Apr;79(4):368-76. doi: 10.1136/jnnp.2007.131045.
citation: Abbruzzese G, Marchese R, Avanzino L, Pelosin E. Rehabilitation for Parkinson's disease: Current outlook and future challenges. Parkinsonism Relat Disord. 2016 Jan;22 Suppl 1:S60-4. doi: 10.1016/j.parkreldis.2015.09.005. Epub 2015 Sep 3.
citation: Allen NE, Song J, Paul SS, Smith S, O'Duffy J, Schmidt M, Love R, Sherrington C, Canning CG. An interactive videogame for arm and hand exercise in people with Parkinson's disease: A randomized controlled trial. Parkinsonism Relat Disord. 2017 Aug;41:66-72. doi: 10.1016/j.parkreldis.2017.05.011. Epub 2017 May 15.
citation: Levin MF. Can virtual reality offer enriched environments for rehabilitation? Expert Rev Neurother. 2011 Feb;11(2):153-5. doi: 10.1586/ern.10.201. No abstract available.