Clinical trial NCT04223544: Incidence of Influenza Infections and Determination of Vaccination Coverage Rate Among Healthcare Workers
Official title: Incidence of Influenza Infections and Determination of Vaccination Coverage Rate Among Hospital and GPs Healthcare Workers During the 2019/2020 Epidemic Season
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Influenza
Vaccination
Attitude of Health Personnel
Keywords: Influenza
Vaccination Coverage Rate
Healthcare Workers
General Practice
Point of Care Testing
Lead sponsor: Wroclaw Medical University
Sponsor class: OTHER
First posted: 2020-01-10
Enrollment: 250
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Healthcare workers of selected General Practices or hospitals wards: doctors, nurses, midwives

Brief summary: The main aim of research is to determine of the prevalence of influenza virus and influenza vaccination coverage rate among hospital and GPs healthcare workers.

Course of research:

Participation in the study is voluntary and carried out after the consent of the examined person. The examination consists of: 1) completing the questionnaire and 2) taking the throat swab twice by the researcher. Two throat swab samples will be taken at the same time. Both samples will be used for virological examination to determine the presence of influenza virus material using non-invasive tests: one sample will be analyzed by a quick 'on-site' test - Flu SensDx kit, while the other sample will be transported to the laboratory, where the reverse transcriptase polymerase chain reaction (RT-PCR) - reference method - will be performed to confirm the presence of influenza genetic material. Swabs are planned to be collected during the 2019/2020 influenza epidemic season (January-March).

In the last stage of the study, the results obtained from the survey questionnaire and the results of virological tests will be subject to statistical analysis and based on the data obtained, conclusions will be drawn from the study, indicating their practical application.

The results obtained from this study will be used to develop a quality improvement program to control influenza virus infection, which will improve the safety of both patients and medical staff.


Eligibility criteria: Inclusion Criteria:

* Healthcare worker of selected General Practices or hospitals wards

Primary outcomes:
measure: Incidence of Influenza Infections
timeFrame: January-March 2020
measure: Vaccination Coverage Rate
timeFrame: January-March 2020
Secondary outcomes:
Other outcomes:
Locations:
city: Wrocław
country: Poland
facility: Family Medicine Department of Wroclaw Medical University
Study officials:
affiliation: Family Medicine Department of Wroclaw Medical University
name: Michal Jedrzejek
role: PRINCIPAL_INVESTIGATOR
References:
citation: Jedrzejek MJ, Mastalerz-Migas A, Janicka P. Incidence of Influenza Virus Infection among Wroclaw's Healthcare Workers in Pre-COVID-19 2019-2020 Influenza Season Using Novel Flu SensDx Device. Int J Environ Res Public Health. 2022 Mar 8;19(6):3159. doi: 10.3390/ijerph19063159.