Clinical trial NCT06458582: High Flow Nasal Cannula is Appropriate Alternative for Stabilization of Very Premature Infants: a Prospective Observational Study
Official title: High Flow Nasal Cannula is Appropriate Alternative for Stabilization of Very Premature Infants: a Prospective Observational Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Premature; Infant
Keywords: neonatology
HFNC
prematurity
Lead sponsor: Charles University, Czech Republic
Sponsor class: OTHER
First posted: 2024-06-13
Enrollment: 65
Sex: ALL
Minimum age (years): 0
Maximum age (years): 2
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: A prospective observational study evaluates the safety and efficacy of using High-Flow Nasal Cannula to stabilize very preterm infants immediately after birth. Following placental transfusion, high flow nasal cannula at 8 l/min is administered along with intermittent tactile stimulation. Criteria for switching to other interventions like continuous positive airway pressure or positive pressure ventilation are set for cases of persistent bradycardia or low SpO2.


Eligibility criteria: Inclusion Criteria:

* Preterm infants born between 28+0 and 31+6 gestational weeks were enrolled in the study after obtaining parental informed consent.

Exclusion Criteria:

* Infants with congenital malformations, previable rupture of membranes, and acute intrauterine hypoxia.

Primary outcomes:
measure: HFNC slabilization
timeFrame: 10 minutes after delivery
Secondary outcomes:
Other outcomes:
Locations:
city: Praha
country: Czechia
facility: Charles University in Prague
state: Czech
Study officials:
References:
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