Clinical trial NCT02229435: Urologic-nephrological Care of Chronic Kidney Disease in Saxony-Anhalt/Magdeburg.
Official title: Laboratory Database-based Analysis of the Interdisciplinary Urologic-nephrological Care of the Chronic Kidney Disease (CKD) With Estimated Glomerular Filtration Rate (eGFR) Under 60 ml/Min of the Population in Saxony-Anhalt / Metropolitan Area Magdeburg.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Chronic Kidney Disease (CKD)
Keywords: Chronic kidney disease
Urological care
Nephrological care
Lead sponsor: University of Magdeburg
Sponsor class: OTHER
Collaborators: name: Medical Laboratory Schenk-Ansorge Magdeburg Germany.
First posted: 2014-09-01
Enrollment: 1031336
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All sampled outpatient patients (blood tests with measurement of serum creatinine) 12/2004-08/2014 of the medical laboratory Prof. Schenk / Dr. Ansorge and Colleagues, GbR, Am Neustädter Feld 47, 39124 Magdeburg, metroplitan area Magdeburg Saxony-Anhalt, Germany.

Brief summary: Statement:

Patients with Chronic kidney disease (CKD) with an estimated glomerular filtration rate (eGFR) under 60 ml/min using the MDRD-6 (Modification of Diet in Renal Disease) formula and/or CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) formula should undergo nephrological and urological care (diagnosis and treatment) to prevent chronic kidney failure. This is recommended by the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (KDOQI), Kidney Disease Improving Global Outcomes (KDIGO) and European Urological Association (EAU). Renal and postrenal diseases can cause or worsen CKD. Internistic and intrarenal diseases can caused or worsen CKD. All diseases affecting CKD should be treated and the medical care should be optimized.

Hypothesis:

Not all patients with CKD receive urological and nephrological care. Interdisciplinary work of outpatient working urologists and nephrologists in the metropolitan area Magdeburg / Saxony-Anhalt Germany is unknown. An descriptive analysis of interdisciplinary treatment connection of CKD patients for an orientating statement is needed.

Detailed description: The Medical Laboratory Schenk-Ansorge Magdeburg Saxony-Anhalt Germany receives all blood samples of outpatient patients of the medical practices of the metropolitan area Magdeburg Saxony-Anhalt Germany. Every patient has a lifetime identification number Independent of the submitting practice. Every submitting medical doctor has a lifetime identification number and is identified by her/his medical subject /specialization. This analysis is based on that laboratory database. For that study a cohort of 1.031.336 patients from 12/2004 to 08/2014 is evaluated, that had been received blood tests with measurement of serum creatinine. For every serum creatinine an eGGR is calculated with the guideline recommended formula.

Eligibility criteria: Inclusion Criteria:

* Measured serum creatinine and estimated glomerular filtration rate
* eGFR \< 60 ml/min

Exclusion Criteria:

* dialysis
* no serum creatinine measured
* Age \< 18 years

Primary outcomes:
measure: Chronic kidney disease
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Magdeburg
country: Germany
facility: Department of Urology University Magdeburg
state: Saxony-Anhalt
Study officials:
affiliation: Urology University Magdeburg
name: Johann J Wendler, Dr.
role: PRINCIPAL_INVESTIGATOR
affiliation: Urology University Magdeburg
name: Martin Schostak, Prof. Dr.
role: STUDY_CHAIR
affiliation: Medical Laboratory Am Neustädter Feld 47, 39124 Magdeburg, Saxony-Anhalt, Germany.
name: Herwart Schenk, Prof. Dr.
role: STUDY_DIRECTOR
affiliation: Doctorand Urology University Magdeburg
name: Constanze Tienken, Cand. med.
role: PRINCIPAL_INVESTIGATOR
References: