Clinical trial NCT05341596: Incidence and Outcome of Reintubation in the PACU
Official title: Incidence and Outcome of Reintubation in the Postanesthesia Care Unit: a Single-center, Retrospective, Observational Matched Cohort Study in China
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Postoperative Complications
Complication of Medical Care
Keywords: general anesthesia
postanesthesia care unit
reintubation after planned extubation
Lead sponsor: Tongji Hospital
Sponsor class: OTHER
First posted: 2022-04-22
Enrollment: 121965
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Reintubation after planned extubation was defined as repeat endotracheal intubation in the PACU after planned extubation of the initial endotracheal intubation for general anesthesia or combined general anesthesia other than that performed in the operating room.

Brief summary: This study evaluated the occurrence of reintubation after planned extubation (RAP), the impact of RAP on duration of PACU stay,length of stay,length of postoperative stay,inpatient healthcare costs, unanticipated ICU admission and readmission.

Detailed description: The study was carried out in Wuhan City, China at a general public university hospital with 62 clinical departments, 99 surgical rooms, and 38 beds in the PACU. The total number of operations performed in this hospital is more than 90,000/year. The study was approved by the hospital ethics committee and was deemed that written patient consent was not required. The adverse events, including RAP, in all patients in the PACU were recorded on a standardized form in a database by pre-trained qualified nurses and/or anesthesiologists at the time of care from January 1, 2017 to December 31, 2019.

Data, including patient demographic and surgical and anesthesia parameters, were obtained from the anesthesia information system. Adverse events management and duration of PACU stay were also documented. For three years, all collected data were filed in a computer every day and were summarized and analyzed every month. Data, such as demographics, airway, oxygen saturation, consciousness, treatment, vital signs, and fast-track criteria scores, were recorded for all patients in the PACU. The first part contained preoperative and intraoperative data, which were entered into the database by the anesthesiologists involved in the patients' intraoperative care from the time of PACU admission. The second part were recorded by nurse and comprised postoperative data from the PACU to the ward or ICU. The third part were recorded by the surgeons and/ or surgical nurses and comprised postoperative data. The criteria for tracheal extubation in the operating room(OR) and the timing of transfer to the PACU were the responsibility of the anesthesiologist.

Eligibility criteria: Inclusion Criteria:

* Patients requiring stay in PACU

Exclusion Criteria:

* Patients were transferred directly from the operating room to the ward or icu
* non-postoperative patient

Primary outcomes:
measure: Duration of PACU stay
timeFrame: through study completion, an average of three months
measure: Length of postoperative stay
timeFrame: through study completion, an average of three months
measure: Unanticipated ICU admission
timeFrame: through study completion, an average of three months
Secondary outcomes:
measure: Inpatient healthcare costs
timeFrame: through study completion, an average of three months
measure: Length of stay
timeFrame: through study completion, an average of three months
measure: Duration of postoperative monitoring
timeFrame: through study completion, an average of three months
measure: Readmission
timeFrame: through study completion, an average of three months
Other outcomes:
Locations:
Study officials:
affiliation: Tongji Hospital
name: Hui Xu
role: STUDY_CHAIR
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