Clinical trial NCT05201196: Task Oriented Training in Post Stroke Patients
Official title: Effects of Task Orientated Training on Dexterous Movement of Hand in Post Stroke Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: Stroke
Task
Training
Movement
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-01-21
Enrollment: 70
Sex: ALL
Minimum age (years): 45
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will be observe the effect of Task-oriented training on the dexterous movements of hands in hemiparetic post-stroke patients. Patient will be recruited that meet the inclusion criteria, with unilateral hemiplegia referred by Neurophysician having stroke for the first time, between age 47-70 year, both males and females, score of spasticity for upper extremity (shoulder, elbow) below and equal 2 based on the Modified Ashworth Scale (MAS), ability to comprehend simple instructions (Mini-Mental State Examination with a minimum score \> 24), Brunnstrom stages ≥ 4, not submitted to other upper-limb rehabilitation programs during the participation in this study. The individuals with recurrent stroke episodes and transient ischemic attack, other neurological diseases (Parkinson's disease, multiple sclerosis,), hemineglect, no sitting balance and comorbidities are excluded. Outcome measures used are FuglMeyer assessment scale (wrist and hand) and Wolf motor function test for upper extremity while Barthel index to assess the activities of daily living. All procedures will perform by taking informed consent. All Ethical standards for both patient and institution will be followed. After collecting data, will apply Shapiro Wilk test to check the normal distribution of data. For analysis use SPSS version 25


Eligibility criteria: Inclusion Criteria:

Unilateral hemiplegic stroke patients referred by Neuro-physician (both ischemic and hemiplegic stroke patients).

* Patient with first time stroke (within 6month of onset).
* Age between 45-70 years of age.
* Gender both male \& females.
* Ability to comprehend simple instructions (Mini-Mental State Examination with a score of \>24 ).
* Score of spasticity for upper extremity (shoulder, elbow) below and equal 2 based on the Modified Ashworth Scale (MAS).
* Motor recovery of upper limb Brunnstrom stages ≥ 4.
* Not participated to other upper-limb rehabilitation programs during the participation in this study.

Exclusion Criteria:

Recurrent stroke attacks, Transient ischemic attacks(TIA).

* Previous injury, disease, or contracture of the upper extremity and no sitting balance.
* Any comorbid neurological disease or condition such as multiple sclerosis, Parkinson disease, spinal cord injury, traumatic brain lesions, brain tumor, epilepsy, or dementia,
* Had Hemineglect phenomena.

Primary outcomes:
measure: Fugl-Meyer Upper Extremity Assessment (FMA-UE)
timeFrame: Pre treatment as baseline
measure: Fugl-Meyer Upper Extremity Assessment (FMA-UE)
timeFrame: Mid treatment after 3 weeks
measure: Fugl-Meyer Upper Extremity Assessment (FMA-UE)
timeFrame: Post treatment after 6 weeks
measure: Wolf Motor Function Test (WMFT)
timeFrame: Pre treatment as baseline
measure: Wolf Motor Function Test (WMFT)
timeFrame: Mid treatment after 3 weeks
measure: Wolf Motor Function Test (WMFT)
timeFrame: Post treatment after 6 weeks
measure: Barthel Index
timeFrame: Pre treatment as baseline
measure: Barthel Index
timeFrame: Mid treatment after 3 weeks
measure: Barthel Index
timeFrame: Post treatment after 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Riphah international university
state: Pakistan(Punjab_
Study officials:
affiliation: Riphah International University
name: Tehreem Mukhtar, MS
role: PRINCIPAL_INVESTIGATOR
References: