Clinical trial NCT06915935: Epidemiological Study of Osteoporosis in the Elderly Population of Shandong Province
Official title: Study on the Epidemiological Characteristics of Osteoporosis and the Diagnostic Significance of Bone Metabolic Biochemical Markers in the Elderly Population of Shandong Province
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Osteoporosis
Osteoporosis (Senile)
Keywords: osteoporosis
epidemiology
elderly
Biochemical indexes of bone metabolism
Lead sponsor: The Second Hospital of Shandong University
Sponsor class: OTHER
First posted: 2025-04-08
Enrollment: 2000
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: According to the level of economic development, population composition, geographical location, cost-effectiveness and feasibility of the program, a total of 10 regions covering five prefecture-level cities in east, west, south, north and middle of Shandong Province were selected to investigate the community population in Shandong Province from August 1, 2023 to January 31, 2026. The inclusion population was residents ≥65 years of age who had lived in the area for more than 6 months in the past 1 year, and the exclusion criteria were cognitive impairment or mental illness.

Brief summary: At present, there is little epidemiological information on osteoporosis in the elderly population of Shandong Province, especially the lack of systematic research on the role of bone metabolism and biochemical indicators in the diagnosis and prognosis of osteoporosis in the elderly population of Shandong Province. The group intends to conduct a study on the epidemiological characteristics of osteoporosis patients and the significance of bone metabolism biochemical indexes in the diagnosis and prognosis of osteoporosis in elderly people in Shandong Province, which includes 1) assessing the prevalence of osteoporosis and the risk factors associated with osteoporosis in the community population, and 2) exploring the role of bone metabolism biochemical indexes in the diagnosis and prognosis of osteoporosis in the hospitalised population. Expected outcomes include the establishment of a database of community and inpatient populations in Shandong Province, publication of research papers, and participation in academic conferences at home and abroad. The database will collect and organise data on osteoporosis in the community and inpatient osteoporosis in Shandong Province, and provide support for subsequent data analysis and research.


Eligibility criteria: Inclusion Criteria:

* Residents ≥65 years of age who had lived in the area for more than 6 months in the past 1 year

Exclusion Criteria:

* People with cognitive impairment or mental illness

Primary outcomes:
measure: Bone mineral density
timeFrame: baseline
Secondary outcomes:
measure: Numerical Rating Scale
timeFrame: baseline
measure: Grip strength test
timeFrame: baseline
Other outcomes:
Locations:
city: Jinan
country: China
facility: Community/rural health service centres
state: Shandong
Study officials:
References: