Clinical trial NCT00961935: Pediatric Bipolar Disorder Study at UCLA
Official title: Examining Neurocognitive Profiles of Bipolar Disorder and Attention-Deficit Hyperactivity Disorder
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Bipolar Disorder
Keywords: bipolar disorder
child bipolar disorder
adolescent bipolar disorder
pediatric bipolar disorder
fMRI
MRI
EEG
neurocognitive tasks
Lead sponsor: University of California, Los Angeles
Sponsor class: OTHER
Collaborators: name: National Institute of Mental Health (NIMH)
name: The State Family Fund
First posted: 2009-08-19
Enrollment: 50
Sex: ALL
Minimum age (years): 7
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Bipolar Disorder

Brief summary: The UCLA Semel Institute for Neuroscience in Los Angeles, CA, is conducting a study looking at similarities and differences in how the brain works between bipolar disorder and attention deficit hyperactivity disorder (ADHD).

Detailed description: Children between the ages of 7 and 17 years old, with a diagnosis of Bipolar I, Bipolar II, or Bipolar NOS, are currently being recruited for this study looking at similarities and differences in how the brain works between bipolar disorder and attention deficit hyperactivity disorder (ADHD). The study involves a comprehensive evaluation at intake, cognitive assessment, EEG, and functional MRI, done over the course of 2 or 3 visits. This study does not provide treatment. However, with participants' consent, the assessment information can be shared with the child's clinician or psychiatrist and a letter with the results from cognitive testing can be prepared, which can be useful in school planning. Referrals for treatment can also be provided.

Eligibility criteria: Inclusion Criteria:

* Subject suffers clinically impairing symptoms of mood lability.
* Child has resided with primary caretaker for at least 6 months.
* Caretaker speaks sufficient English to complete all study evaluations and measures.

Exclusion Criteria:

* Lifetime history of mental retardation, autism, or primary diagnosis of psychosis.
* Subject is pregnant or nursing.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Los Angeles
country: United States
facility: UCLA Semel Institute for Neuroscience and Human Behavior
state: California
Study officials:
affiliation: University of California, Los Angeles
name: Patricia Walshaw, Ph.D.
role: PRINCIPAL_INVESTIGATOR
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