Clinical trial NCT05923151: The Cranial-caudal Mixed Medial Approach for Laparoscopic Right Hemicolectomy
Official title: Techniques and Advantages of the Cranial-caudal Mixed Medial Approach for Laparoscopic Right Hemicolectomy With Complete Mesocolic Excision
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Intraoperative Blood Loss
Postoperative Complications
Pathology
Lead sponsor: Subei People's Hospital of Jiangsu Province
Sponsor class: OTHER
Collaborators: name: Yangzhou University
First posted: 2023-06-28
Enrollment: 148
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To explore the feasibility and effectiveness of the cranial-caudal mixed medial approach in laparoscopic right hemicolectomy with complete mesocolic excision. Laparoscopic right hemicolectomy using the cranial-caudal mixed medial approach is safe and feasible, can shorten the operation time, reduce the risk of intraoperative bleeding, and has good clinical results.

Detailed description: The data of patients undergoing laparoscopic right hemicolectomy performed in the same surgical group of gastrointestinal surgery at Northern Jiangsu People's Hospital from February 2017 to June 2022 were retrospectively analyzed. According to different surgical approaches, patients were divided into the cranial-caudal mixed medial approach group and the medial approach group.

Intraoperative and postoperative data were collected. Intraoperative data is obtained through surgical records and pathological reports, including total operation time, Laparoscopic procedure time, Intraoperative blood loss, sample length, number of lymph nodes collected, and number of positive lymph nodes. Postoperative data includes exhaust time, liquid intake time, postoperative hospitalization and complications. Among them, complications are short-term postoperative complications (surgical related complications, non-surgical related complications) within the first 30 days after surgery (or throughout the hospitalization period, if more than 30 days, and are classified according to the Clavien-Dindo classification method.

To explore the feasibility and effectiveness of the cranial-caudal mixed medial approach in laparoscopic right hemicolectomy with complete mesocolic excision.

Eligibility criteria: Inclusion Criteria:

* Age range: 18-70 years old
* Right colon cancer confirmed by colonoscopy and pathological diagnosis
* Single primary tumor without distal metastasis
* Laparoscopic operation

Exclusion Criteria:

* Age below 18 and above 70 years old
* Patients who need urgent surgery
* Persons with a history of malignant tumors
* Multiple primary tumors or distant metastases

Primary outcomes:
measure: The operative time
timeFrame: Surgery start (skin incision time) - Surgery end (suture incision end time)
Secondary outcomes:
measure: Intraoperative blood loss
timeFrame: Surgery start (skin incision time) - Surgery end (suture incision end time)
Other outcomes:
measure: Number of lymph nodes cleaned
timeFrame: 3-5 days after surgery
measure: Anastomotic leakage
timeFrame: Within 30 days after surgery
measure: Liver failure
timeFrame: Within 30 days after surgery
measure: Renal failure
timeFrame: Within 30 days after surgery
Locations:
city: Yangzhou
country: China
facility: Subei People's Hospital
state: Jiangsu
Study officials:
References: