Clinical trial NCT05250453: Quality of the Cardio-pulmonary Resuscitation
Official title: Cardiopulmonary Resuscitation; Epidemiology, Quality, Survival and Injuries.
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Cardiopulmonary Resuscitation
Keywords: CPR, injuries, OHCA
Lead sponsor: Tampere University Hospital
Sponsor class: OTHER
Collaborators: name: National Istitute For Health and Welfare, Finland
First posted: 2022-02-22
Enrollment: 400
Sex: ALL
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All cardiac arrest patients in Etelä-Pohjanmaa and Pirkanmaa, Finland

Brief summary: Patients having sudden cardiac arrest have very poor prognosis. It is devastating for patient and family. But also very expensive for nations economics when working-age people die or disable due to cardiac arrest. Recent studies have shown that high quality of cardiopulmonary resuscitation (CPR) and minimized delays increases the survival after cardiac arrest. In this objective prospective study we will use Zoll´s X Series defibrillator on every emergency medicine systems (EMS´s) unit in Pirkanmaa area, Finland, to collect information on CPR quality. Real CPR Help® will collect the information on depth, frequency and pauses during CPR. We will make an Utstein analysis on OHCA during one year period and compare the results on Utstein analysis made in the same area on 2013-2014. We will analyse the quality of CPR and compare it to the outcome from OHCA and neurological outcome 3 months after resuscitation. In addition we will analyse the CPR related injuries and compare these to the compression depth and number of persons performing CPR.

In one part of the study we will evaluate the incidence of OHCA in different risk areas of Pirkanmaa and analyse the influence of time delay and location to the outcome out of hospital and neurological outcome 3 months after resuscitation. We will also analyse if the time of post-resuscitation care before getting to the hospital or stenosis in carotid artery affects the outcome from OHCA and neurological outcome 3 months after resuscitation.


Eligibility criteria: Inclusion Criteria:

* cardiac arrest
* \> 18 years of age

Exclusion Criteria:

* \< 18 years of age
* prisoners

Primary outcomes:
measure: QualityCPR
timeFrame: 1 year
measure: Neurological survival after CA
timeFrame: 3 months after OHCA
Secondary outcomes:
measure: CPR related injuries
timeFrame: 1 year
measure: Stenosis of the carotid artery
timeFrame: 3 months after OHCA
measure: the dispatch calls concerning OHCA
timeFrame: 1 year
measure: the quality of the postresuscitation care
timeFrame: 3 months after OHCA
Other outcomes:
Locations:
city: Tampere
country: Finland
facility: Tampere University hospital
Study officials:
affiliation: Tampere University Hospital
name: Piritta Setälä, PhD
role: STUDY_DIRECTOR
affiliation: Tampere University Hospital
name: Sanna Hoppu, PhD
role: STUDY_DIRECTOR
affiliation: Tampere University Hospital
name: Jyrki Ollikainen, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Tampere University Hospital
name: Kati Järvelä, PhD
role: STUDY_DIRECTOR
affiliation: Tampere University Hospital
name: Valtteri Järvenpää, MB
role: PRINCIPAL_INVESTIGATOR
affiliation: Tampere University Hospital
name: Ville Jalkanen, PhD
role: STUDY_DIRECTOR
affiliation: Tampere University Hospital
name: Joonas Tirkkonen, PhD
role: STUDY_DIRECTOR
affiliation: Tampere University
name: Heini Huhtala, PhD
role: STUDY_DIRECTOR
affiliation: Finnish Institute for Health and Welfare
name: Mika Martiskainen, PhD
role: STUDY_DIRECTOR
affiliation: Tampere University Hospital
name: Riikka Nevalainen, MD
role: STUDY_DIRECTOR
References: