Clinical trial NCT06952244: Functional Status in Hospitalized Endocrine Disorders
Official title: Investigation of Clinical and Functional Characteristics of Endocrinology Patients During Hospitalization
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Endocrine Diseases
Hospitalized
Keywords: endocrine diseases
functional assessment
clinical assesment
Hospitalization
Individuals with endocrine disorders
Lead sponsor: Uşak University
Sponsor class: OTHER
First posted: 2025-04-30
Enrollment: 200
Sex: ALL
Minimum age (years): 18
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: The sample of the study consists of patients aged between 18-64 years who are hospitalized in the Endocrinology Department of Uşak Training and Research Hospital.

Brief summary: The aim of this observational study was to examine the clinical and functional characteristics of patients hospitalized in the endocrinology department of a university hospital. In line with this purpose, the following research questions were given.

What are the respiratory functions and respiratory rates of patients hospitalized in the endocrinology department? What are the muscle strengths of patients hospitalized in the endocrinology department? What is the general health status of patients hospitalized in the endocrinology department? What is the quality of life of patients hospitalized in the endocrinology department? What is the fatigue status of patients hospitalized in the endocrinology department? What is the level of independence of patients hospitalized in daily living activities of patients hospitalized in the endocrinology department? What are the routine blood values of patients hospitalized in the endocrinology department? What is the sleep quality of patients hospitalized in the endocrinology department? What are the physical activity levels of patients hospitalized in the endocrinology department? What is the balance status of patients hospitalized in the endocrinology department? What is the neuropathic pain status of patients hospitalized in the endocrinology department? The patients hospitalized in the Endocrinology Department of Uşak Education and Research Hospital constitute the sample of the study. Clinical and functional evaluations will be made from the participants during their hospital stay. In this context, respiration, muscle strength, general pain assessment, life expectancy, fatigue, independence levels, sleep quality, routine blood values, physical activity levels, balance status and neuropathic status evaluation will be made.

Detailed description: The endocrine system is a system responsible for the production of hormones that regulate vital functions such as metabolism, growth, reproduction and energy balance. Endocrine diseases can seriously affect the general health status, functional capacity and quality of life of individuals by causing disruptions in these functions. Endocrine patients usually require hospitalization due to chronic symptoms caused by metabolic and hormonal imbalances. During this process, negative changes may occur in many clinical, physical and functional characteristics.

Clinical Features: Parameters such as routine blood values, respiratory functions and muscle strength play a critical role in monitoring the general health status of patients.

Functional Features: Factors such as independence in daily living activities, balance, physical activity level and sleep quality are important elements that should be evaluated during the hospitalization period of patients.

Main Problems Encountered by Endocrinology Patients Metabolic Problems: Conditions such as hyperglycemia, hypoglycemia, electrolyte imbalances and insulin resistance are frequently seen.

Loss of Muscle and Functional Capacity: Endocrine diseases can negatively affect muscle strength and limit the independence and daily living activities of individuals.

Sleep and Fatigue Problems: Hormonal imbalances can reduce quality of life by affecting sleep quality and energy levels.

Balance and Coordination Difficulties: Complications such as diabetic neuropathy can affect neuromuscular functions and lead to balance problems.

Psychosocial Effects: Psychological effects such as chronic fatigue, depression, and decreased quality of life have been widely reported. This study aims to comprehensively evaluate the conditions of endocrinology patients during their hospitalization and understand the relationship between both clinical and functional characteristics. Such an approach provides basic data for better management of patients, development of treatment protocols, and improvement of hospitalization processes.

Focus Points of the Study Sociodemographic Characteristics Examination: Understanding the effects of factors such as age, gender, and education level on clinical and functional outcomes.

Analysis of Clinical Parameters: Evaluating the role of biophysical measurements such as routine blood values and respiratory functions in the disease process.

Functional Capacity Assessment: Determining the effects of muscle strength, balance, and physical activity levels on daily life.

Measuring Quality of Life: To investigate how health-related quality of life is affected by factors such as sleep quality and fatigue.

Research on endocrine diseases shows that these patients often face long hospitalization periods, high risk of complications, and reduced quality of life. Measurements such as muscle strength, respiratory function, and balance are used to estimate both the health status of individuals and the recovery process. Quality of life is affected not only by physical health but also by psychosocial and environmental factors. The findings of this study can be used to determine the difficulties experienced by endocrine patients during the hospitalization process and areas for improvement during this process. It can also guide the development of individualized treatment and rehabilitation programs. Based on this, the aim of the study was to examine the clinical and functional characteristics of patients hospitalized in the endocrinology department of a university hospital.

Eligibility criteria: Inclusion Criteria:

* Being between the ages of 18-64
* Being a volunteer
* Being hospitalized in the endocrinology ward.

Exclusion Criteria:

* Patients who have any obstacles to participating in surveys and measurements,
* Patients with missing data for any reason, and patients who are not accepted to the endocrinology service

Primary outcomes:
measure: Assessment of respiratory functions
timeFrame: At the time of enrollment
measure: Chest circumference measurement
timeFrame: At the time of enrollment
measure: Assessment of muscle strength
timeFrame: At the time of enrollment
measure: Pain assessment
timeFrame: At the time of enrollment
measure: Quality of life assessment
timeFrame: At the time of enrollment
measure: Fatigue assessment
timeFrame: At the time of enrollment
measure: Assessing their independence in activities of daily living
timeFrame: At the time of enrollment
measure: Routine Blood Values Examination
timeFrame: At the time of enrollment
measure: Evaluation of sleep quality
timeFrame: At the time of enrollment
measure: The physical activity level
timeFrame: At the time of enrollment
measure: Balance assessment
timeFrame: At the time of enrollment
measure: Neuropathy evaluation
timeFrame: At the time of enrollment
Secondary outcomes:
Other outcomes:
Locations:
city: Uşak
country: Turkey
facility: Uşak Education and Research Hospital
Study officials:
affiliation: Uşak University
name: Kevser Gursan, Dr.
role: PRINCIPAL_INVESTIGATOR
References: