Clinical trial NCT06811753: Impact of Robotic Surgery on Systemic Immune-inflammation Index
Official title: Impact of Robotic Surgery on Systemic Immune-inflammation Index in Gastric Cancer Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Gastric Cancer
Keywords: gastric cancer
minimally invasive gastrectomy
systemic immune-inflammation index
Robotic surgery
Lead sponsor: Başakşehir Çam & Sakura City Hospital
Sponsor class: OTHER_GOV
First posted: 2025-02-06
Enrollment: 300
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients operated for gastric cancer

Brief summary: Robotic surgery has been gaining attention because of the physical and metabolic morbidity of the conventional open technique.The systemic immune-inflammation index(SII) has emerged as a recent and more reliable biomarker.In our single-center retrospective cohort study, the investigators investigate SII in robotic gastrectomy in order to show the advantageous effect on immune system which the investigators think as the first study in the literature.

Detailed description: Patients who underwent robotic gastrectomy between January 2021 and September 2024 were included in the study. The primary outcome was to ascertain the beneficial effects of robotic surgery in gastric cancer patients in terms of immune response. The secondary outcome was to examine the reliability of SII as a serum biomarker in comparison to previous studies on the diagnosis and postoperative follow-up of gastric cancer.

Eligibility criteria: Inclusion Criteria:

gastric cancer patients treated with surgery

Exclusion Criteria:

patients with haematologic malignancy, immune system disorder, antiplatelet drug usage, operations including splenectomy

Primary outcomes:
measure: Systemic inflammatory index
timeFrame: One year
Secondary outcomes:
Other outcomes:
Locations:
city: İstanbul
country: Turkey
facility: Basaksehir Cam and Sakura City Hospital
state: Basakşehir
Study officials:
affiliation: Başakşehir Çam & Sakura City Hospital
name: Yiğit Düzköylü, assoc. prof.
role: PRINCIPAL_INVESTIGATOR
References:
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