Clinical trial NCT06342882: Dysphagia Severity and Functional Independence Level
Official title: Functional Independence Levels Associated With Dysphagia Severity in Patients With Neurological Diseases
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Dysphagia
Neurologic Disorder
Keywords: dysphagia
functional independance
Lead sponsor: Atılım University
Sponsor class: OTHER
First posted: 2024-04-02
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Patients with neurological disorders

Brief summary: Functional independence is the ability of a person to perform daily life activities safely without any restriction, as much as possible. The functional independence depends on physical, social, cognitive and psychological abilities of the person. Therefore, full functional independence requires the harmony of all these parameters.

Dysphagia can be seen in more than 50% of neurological patients, and it is called neurogenic dysphagia. Muscle weakness, tonus changes, sensory loss and coordination problems occur in these patients. Pain and fatigue are also frequently observe. These patients have problems with fine and gross motor movements, and thereby mobility and transfer activities become difficult. Life-threatening complications such as pulmonary problems, malnutrition and dehydration accompany when patients have dysphagia. Both neurological and dysphagia-related problems negatively affect the physical, psychological, emotional and cognitive functions of patients. Neurological patients with dysphagia may have more serious clinical situations due to more affected vital functions such as pulmonary functions and feeding.

Dysphagia-induced malnutrition adversely affects many systems, including the musculoskeletal system. In a study conducted in the elderly with dysphagia, atrophy in the total muscle mass and swallowing muscles, and increase in intramuscular adipose tissue were reported as a result of malnutrition. Decreases in the muscle mass may negatively affect the functional independence of patients with dysphagia. Other studies in geriatric population have shown that swallowing function is associated with hand grip strength and quadriceps muscle strength, which are indicators of functional independence in activities of daily living (ADL). These studies also suggest that dysphagia may be associated with functional independence in geriatric group. Therefore, functional independence may also reduce in patients with neurogenic dysphagia. However, there is no study investigating the relationship between dysphagia severity and the functional independence levels in patients with neurological diseases. Therefore, the investigators aimed to investigate the relationship between dysphagia severity and functional independence level in patients with neurological diseases.


Eligibility criteria: Inclusion Criteria:

* aged between 18-65 years
* independent to walk 3 meters
* underwent a Modified Barium Swallowing Study (MBSS).

Exclusion Criteria:

* having any cervical pathology that may affect swallowing physiology,
* history of rheumatological diseases
* having any orthopedic surgery in the previous 6 months
* using a wheelchair.

Primary outcomes:
measure: dysphagia severity
timeFrame: 1 day
measure: functional independence
timeFrame: 1 day
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Atılım Uiveristy
state: Incek
Study officials:
affiliation: Hacettepe University
name: selen serel arslan, Prof
role: STUDY_DIRECTOR
References: