Clinical trial NCT06834646: Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location
Official title: Comparison of 30-day Morbidity and Mortality in Cancer Patients Based on Emergency Department Location: Referring Oncology Hospital Vs Other Hospitals.
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Cancer
Cancer Remission
Keywords: Emergency Department
Cancer
Mortality
morbidity and mortality in Cancer
Lead sponsor: Assistance Publique - Hôpitaux de Paris
Sponsor class: OTHER
First posted: 2025-02-19
Enrollment: 2000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients followed for cancer and consulting the emergency department

Brief summary: Patients being followed for cancer account for 2.8% of emergency admissions in France. An acute episode that triggers a visit to the emergency department may be related to the progression of the disease, or to complications of treatment. The management of these patients is often complex and requires a degree of expertise. Emergency departments specialising in the management of cancer complications have been set up, and now deal exclusively with patients treated at their centres. However, for geographical or logistical reasons, patients with cancer are likely to consult a non-specialist emergency department and/or one located outside the cancer care centre. In this case, the emergency doctor may not have access to the oncology file, and care in the emergency department and downstream services may be sub-optimal. Studies have shown a positive impact on the quality of care and prognosis of patients thanks to the cancer centre's expertise. However, the effect of the centre on a cancer patient who visits the emergency department has never been studied. This is particularly true if the emergency department where the patient is seen is located in the cancer follow-up centre.

The primary objective of the COVER study is to investigate the impact of the location of the emergency department where the patient is seen for their prognosis.


Eligibility criteria: Inclusion Criteria:

Patients aged 18 or over admitted to an emergency department with cancer that has been active or in remission for less than a year.

Exclusion Criteria:

- Opposition to participate in the study

Primary outcomes:
measure: Number of days alive spent outside the hospital
timeFrame: 1 month
Secondary outcomes:
measure: Occurrence of a new/ unscheduled consultation
timeFrame: 30 days
measure: Length of hospitalisation
timeFrame: 90 day
measure: Unscheduled consultation or hospitalization emergency department discharge
timeFrame: 7 days
measure: Unexpected death
timeFrame: 7 days
measure: Secondary admission to the intensive care unit during the initial hospitalization following the emergency visit
timeFrame: 7 days
measure: Occurence of organ failure
timeFrame: 7 days
measure: Quality of life with QLQ-C30
timeFrame: 90 days
measure: Mortality
timeFrame: 30 days
measure: Mortality
timeFrame: Day 90
Other outcomes:
Locations:
city: Paris
country: France
facility: Hôpital Pitié Salpêtrière Emergency department
Study officials:
References: