Clinical trial NCT06847022: Efficacy of Ultrasound-guided Transversalis Fascia Plane Block (TFPB) in Controlling Postoperative Pain After Transverse Incision in Gynecologic Surgery
Official title: Efficacy of Ultrasound-guided Transversalis Fascia Plane Block (TFPB) in Controlling Postoperative Pain After Transverse Incision in Gynecologic Surgery
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Transversalis Fascia Plane Block
Gynecologic Surgical Procedures
Keywords: Transversalis fascia plane block
open gynecologic surgery
transverse incision
Lead sponsor: Thammasat University
Sponsor class: OTHER
First posted: 2025-02-26
Enrollment: 32
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Transversalis fascia plane block (TFPB) has been studied and has shown to be very effective in controlling postoperative pain after caesarean section but has not been studied in open gynecologic surgery with transverse incision. Inadequate pain control after open gynecologic surgery is associated with negative consequences such as chronic pelvic pain. We would like to study the efficacy of TFPB in controlling postoperative pain after open gynecologic surgery with transverse incision.


Eligibility criteria: Inclusion Criteria:

* Patients who undergoing open gynecologic surgery under general anesthesia
* Age 18 - 70 years
* ASA Physical status I-III
* Transverse incision

Exclusion Criteria:

* Creatinine clearance is less than 30 ml/min
* Body weight \< 50 kg
* Re-open surgery
* Persistent chronic pelvic pain
* Allergic to medications used in this study

Primary outcomes:
measure: Postoperative 24 hours morphine requirement
timeFrame: 24 hours
Secondary outcomes:
measure: postoperative pain score
timeFrame: 1 hour, 6 hours, 24 hours
measure: Side effects from postoperative opioids
timeFrame: 24 hours
measure: Incidence of chronic pelvic pain
timeFrame: 3 months
Other outcomes:
Locations:
city: Pathum Thani
country: Thailand
facility: Department of Anesthesiology, Faculty of Medicine, Thammasat University
Study officials:
affiliation: Faculty of Medicine, Thammasat University
name: Assist. Prof. Dr. Preeyaphan Arunakul, M.D., FRCAT
role: PRINCIPAL_INVESTIGATOR
References:
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