Clinical trial NCT06887725: Exercise Training and Knee Joint Proprioception in Rheumatoid Arthritis
Official title: The Effect of Exercise Training on Knee Joint Proprioception in Patients With Rheumatoid A Exercise Training on Knee Joint Proprioception in Patients With Rheumatoid Arthritisrthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Rheumatic Arthritis
Keywords: exercise
proprioception
biopsychosocial model
knee
muscle strength
Lead sponsor: Hacettepe University
Sponsor class: OTHER
Collaborators: name: Hacettepe University
name: Hasan Kalyoncu University
First posted: 2025-03-20
Enrollment: 19
Sex: ALL
Minimum age (years): 45
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: randomized controlled trial
Primary purpose: TREATMENT

Brief summary: Rheumatoid arthritis (RA) is a chronic disorder that affects 0.5% to 1% of adults and is the result of an autoimmune attack against joint tissues. In recent years, advances in anti-rheumatoid drugs and treatment strategies have improved the health status of patients with RA. However, many patients do not achieve disease remission and experience progressive functional impairment. According to 2003 data from the National Health Interview Survey in the United States, by 2030, approximately 25% of adults aged 18 years and older are expected to have doctor-diagnosed arthritis, and 9.3% of adults are expected to have arthritis-related activity limitations.

In order for patients with RA to perform activities of daily living, it is very important for them to maintain their balance, i.e., their sense of proprioception. It is known that knee proprioception is decreased in RA. In addition, the presence of pain, decreased muscle strength, and functionality in patients with RA lead many of them to adopt a sedentary lifestyle.

The main aim of this study was to evaluate the effects of exercise training on knee joint proprioception in individuals with RA. In addition, it also aims to examine how exercise training improves pain, functionality, performance, fear of falling, biopsychosocial status, and quality of life. The importance of this research is that it provides more scientific data for improving knee joint proprioception in individuals with RA and guides clinical practice. It is also expected to contribute to the development of a comprehensive approach to improving the quality of life of patients by demonstrating not only the physical but also the psychological and functional effects of exercise training.


Eligibility criteria: Inclusion Criteria:

* Being diagnosed with RA
* Being able to walk
* Being between the ages of 40-65.
* Accepting to participate in the study and approving the informed consent form.
* Being literate and able to use technological devices.

Exclusion Criteria:

* Having acute inflammatory pathology in the knee joint.
* Knee arthroplasty surgery.
* Intra-articular or systemic corticosteroid use in the last 3 months.
* Having participated in an FTR program in the last 3 months.
* Advanced musculoskeletal, cardiac or peripheral vascular disease.
* Significant system or organ failure.
* Having a disease that will affect cognitive functions such as Alzheimer's disease or dementia

Primary outcomes:
measure: Cognitive Exercise Therapy Approach (BETY)- Biopsychosocial Questionnaire
timeFrame: 3 mounths
Secondary outcomes:
measure: Proprioception of the knee joint
timeFrame: 3 mounths
measure: Health Assessment Questionnaire (HAQ)
timeFrame: 3 mounths
measure: Hospital Anxiety Depression Scale (HADS)
timeFrame: 3 mounths
measure: WOMAC Osteoarthritis Index
timeFrame: 3 mounths
measure: McGill pain scale short form (SF McGill)
timeFrame: 3 mounths
measure: Time Up and Go Test
timeFrame: 3 mounths
measure: 10-step stair climbing test
timeFrame: 3 mounths
measure: 6 min walk test
timeFrame: 3 mounths
measure: Fall efficacy scale
timeFrame: 3 mounths
measure: World health organization quality of life scale-short form (WHOQOL-BREF)
timeFrame: 3 mounths
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
state: Altındağ
Study officials:
References: