Clinical trial NCT03663569: A Study on the Control of Chronic Obstructive Pulmonary Disease (COPD) in Patients Taking the Combination of Tiotropium and Olodaterol Using the Respimat® Inhaler
Official title: Changes in Clinical Control of COPD Patients Measured by the Clinical COPD Questionnaire During Therapy With Spiolto®Respimat® in Routine Clinical Practice
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pulmonary Disease, Chronic Obstructive
Lead sponsor: Boehringer Ingelheim
Sponsor class: INDUSTRY
First posted: 2018-09-10
Enrollment: 4819
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Around 4500 COPD patients from approximately 11 countries will be collected, with a signed informed consent will be maintained in the ISF at the investigational site irrespective of whether they have been treated or not.

Brief summary: Open-label observational study which includes COPD patients that are receiving treatment with Spiolto® Respimat® for approximately 6 weeks, which is the average time between two medical consultations.


Eligibility criteria: Inclusion Criteria:

* Written informed consent prior to participation
* Female and male patients ≥40 years of age
* Patients diagnosed with COPD and based upon the investigator's decision requiring a new prescription of Spiolto Respimat® (combination of two long-acting bronchodilators) according to Spiolto® Respimat® SmPC, GOLD COPD Strategy Document 2018 (GOLD COPD groups B to D) and local COPD guidelines

Exclusion Criteria:

* Patients with contraindications according to Spiolto® Respimat® SmPC
* Patients already on a LABA/LAMA combination (free and fixed dose) in the last 6 weeks before study entry
* Patients continuing LABA/ICS treatment should not be additionally treated with Spiolto® Respimat® in order to avoid a double dosing of long-acting beta-agonists
* Pregnancy and lactation
* Current participation in any clinical trial or any other non-interventional study of a drug or device.

Primary outcomes:
measure: Percentage of Patients With Therapeutic Success of Spiolto® Respimat® Treatment at Visit 2
timeFrame: At Visit 2 (6 weeks after baseline visit 1)
Secondary outcomes:
measure: Changes in the Clinical COPD Questionnaire (CCQ) and the CCQ Symptom, Mental State and Functional State Domain Scores From Visit 1 (Baseline) to Visit 2
timeFrame: At baseline visit 1 and 6 weeks thereafter at visit 2
measure: Physician's Global Evaluation (PGE) Score at Visit 1(Baseline)
timeFrame: At visit 1
measure: Physician's Global Evaluation (PGE) Score at Visit 2
timeFrame: At visit 2 (6 weeks after baseline visit 1)
measure: Patient Overall Satisfaction With Spiolto® Respimat® Treatment at Visit 2
timeFrame: At visit 2 (6 weeks after baseline visit 1)
measure: Patient Satisfaction With Inhaling From the Respimat® Device at Visit 2
timeFrame: At visit 2 (6 weeks after baseline visit 1)
measure: Patient Satisfaction With Handling of the Respimat® Inhalation Device at Visit 2
timeFrame: At visit 2 (6 weeks after baseline visit 1)
measure: Number of Participants Willing to Continue Treatment With Spiolto® Respimat® at Visit 2
timeFrame: At visit 2 (6 weeks after baseline visit 1)
Other outcomes:
Locations:
city: Dupnitza
country: Bulgaria
facility: MBAL Sveti Ivan Rilski-2003
city: Gabrovo
country: Bulgaria
facility: SBALBB "Pencho Semov" - Gabrovo EOOD
city: Haskovo
country: Bulgaria
facility: SBALPFZ Haskovo EOOD
city: Karlovo
country: Bulgaria
facility: MBAL Kiro Popov EOOD
city: Kozloduj
country: Bulgaria
facility: MBAL Sv. Ivan Rilski EOOD
city: Lovech
country: Bulgaria
facility: MBAL "Prof. Dr P. Stoyanov" AD - Mihail Kirov
city: Plovdiv
country: Bulgaria
facility: Iliana Valkanova
city: Plovdiv
country: Bulgaria
facility: MBAL Sveti Panteleimon
city: Razgrad
country: Bulgaria
facility: "Medical Center-Razgrad"OOD
city: Razgrad
country: Bulgaria
facility: Medical Center Re Spiro OOD
city: Sliven
country: Bulgaria
facility: MBAL Sliven to VMA Sofia
city: Smolyan
country: Bulgaria
facility: Grigor Lalov
city: Sofia
country: Bulgaria
facility: SBALPFZ-Sofia district EOOD
city: Stara Zagora
country: Bulgaria
facility: Prevencia 2000 MCDMP OOD
city: Varna
country: Bulgaria
facility: Medical Center "Research expert" OOD
city: Veliko Tarnovo
country: Bulgaria
facility: Medical Center "Tara" OOD
city: Vidin
country: Bulgaria
facility: MC"Sv.Ivan Rilski"OOD
city: Bilina
country: Czechia
facility: MUDr. Alena Jelinkova
city: Boskovice
country: Czechia
facility: MUDr. Eva Krizova
city: Brno
country: Czechia
facility: Ambulance pro nemoci plicni a TBC, s.r.o.
city: Brno
country: Czechia
facility: Jana Jančíková
city: Brno
country: Czechia
facility: MUDr Hana Vašínová
city: Brno
country: Czechia
facility: MUDr. Ilona Binkova
city: Brno
country: Czechia
facility: MUDr. Jana Slapnickova s.r.o.
city: Brno
country: Czechia
facility: MUDr. Jaroslava Lovakova
city: Broumov
country: Czechia
facility: MUDr. Michal Svarc
city: Ceske Budejovice
country: Czechia
facility: MUDr. Jan Faktor Medipont s.r.o.
city: Ceske Budejovice
country: Czechia
facility: MUDr. Josef Hlavac Medipont s.r.o.
city: CeskyTesinKonakov
country: Czechia
facility: MUDr. Martin Polasek
city: Dobřís
country: Czechia
facility: MUDr. Jiri Guthwirth
city: Děčín
country: Czechia
facility: MUDr. Renata Bilkova
city: Frydek-Mistek
country: Czechia
facility: MUDr. Martin Adamec Alergonet Group
city: Havlickuv Brod
country: Czechia
facility: MUDr. Marie Buresova
city: Holesov
country: Czechia
facility: MUDr. Jana Psikalova
city: Holesov
country: Czechia
facility: MUDr. Stanislava Bednarova
city: Hořovice
country: Czechia
facility: MUDr. Petr Šafránek
city: Hradec Kralove
country: Czechia
facility: MUDr. Hana Lochmanova AXIMED s.r.o.
city: Hranice
country: Czechia
facility: MUDr. Ales Bohac Plicni ambulance
city: Hustopece U Brna
country: Czechia
facility: MUDr. Lenka Fousova
city: Jihlava
country: Czechia
facility: MUDr. Bohumil Kralicek
city: Jihlava
country: Czechia
facility: MUDr. Jirina Knillova
city: Jirkov
country: Czechia
facility: MUDr. Alexandra Woznicova
city: Kosmonosy
country: Czechia
facility: MUDr. Michaela Baerova
city: Kyjov
country: Czechia
facility: MUDr. Petr Kolman
city: Liberec
country: Czechia
facility: MUDr. Milanda Sipkova
city: Louny
country: Czechia
facility: Plucni Ambulance Louny s.r.o.
city: Miroslav
country: Czechia
facility: MUDr. Ilona Pavlisova, s.r.o.
city: Mlada Boreslav
country: Czechia
facility: MUDr. Michaela Baerova
city: Novy Jicin
country: Czechia
facility: MUDr. Dusan Velart
city: Novy Jicin
country: Czechia
facility: MUDr. Sarka Hofrova
city: Nymburk
country: Czechia
facility: MUDr. Sarka Klimesova
city: Náchod
country: Czechia
facility: MUDr. Pavla Shihatova
city: Olomouc
country: Czechia
facility: MUDr. Ondrej Sobotik
city: Orlová - Lutyně
country: Czechia
facility: MUDr. RAdoslav Alexa
city: Ostrava, Bělský Les
country: Czechia
facility: Plicní-ambulance Terezie Janásková, s.r.o
city: Ostrava
country: Czechia
facility: MUDr. Milena Sramkova
city: Ostrava
country: Czechia
facility: MUDr. Jana Balounova
city: Ostrava
country: Czechia
facility: MUDr. Jana Kocianova
city: Pardubice
country: Czechia
facility: MUDr. Tereza Dobesova Aximed s.r.o.
city: Pardubice
country: Czechia
facility: MUDr. Miluse Zitkova
city: Pelhřimov
country: Czechia
facility: MUDr. Jiri Zoula Aries Medici s.r.o.
city: Plzen
country: Czechia
facility: MUDr. Petr Hartman
city: Plzen
country: Czechia
facility: MUDr. Jitka Smolova
city: Plzen
country: Czechia
facility: MUDr. Vladimir Makrlik
city: Plzen
country: Czechia
facility: MUDr. Andrea Svabkova
city: Plzeň
country: Czechia
facility: MUDr. Petr Šafránek
city: Poděbrady
country: Czechia
facility: MUDr. Jana Janková Zátopková
city: Pohorelice
country: Czechia
facility: MUDr. Olga Krizova
city: Praha 1
country: Czechia
facility: První plicní ambulance s.r.o.
city: Praha 4
country: Czechia
facility: MUDr. Romana Davidova
city: Praha 5
country: Czechia
facility: MUDr. Iva Stachova
city: Praha 5
country: Czechia
facility: MUDr. Ivana Zatloukalova
city: Praha 6
country: Czechia
facility: MUDr. Milada Typltová
city: Praha 6
country: Czechia
facility: MUDr. Jana Jirouskova
city: Praha 6
country: Czechia
facility: MUDr. Lenka Povysilova
city: Praha 7
country: Czechia
facility: MUDr. Vera Reichmanova
city: Praha 7
country: Czechia
facility: MUDr. Vera Pacovska
city: Praha 9
country: Czechia
facility: MUDr. Bronislava Viest
city: Praha 9
country: Czechia
facility: MUDr. Ivana Boučková
city: Praha
country: Czechia
facility: MUDr. Fransitek Petrik
city: Praha
country: Czechia
facility: MUDr. Ivana Jirmanova
city: Prostejov
country: Czechia
facility: MUDr. Romana Ivankova
city: Rokycany
country: Czechia
facility: MUDr. Helena Ringlerova
city: Strakonice
country: Czechia
facility: MUDr. Jaroslav Mares
city: Usti nad Labem
country: Czechia
facility: MUDr. Alena Kortusova
city: Usti nad Labem
country: Czechia
facility: MUDr. Olga Martinkovicova
city: Valasske Mezirici
country: Czechia
facility: MUDr. Pavel Stach
city: Veselí nad Moravou
country: Czechia
facility: MUDr. Eva Sabova
city: Zabreh Na Morave
country: Czechia
facility: MUDr. Pavel Matuska
city: Zidlochovice
country: Czechia
facility: MUDr. Alena Prochazkova
city: Čáslav
country: Czechia
facility: Plicní Čáslav s.r.o.
city: Šumperk
country: Czechia
facility: MUDr. Margit Hóracková
city: Žamberk
country: Czechia
facility: MUDr. Jiri Dolecek
city: Žamberk
country: Czechia
facility: MUDr. Michal Pasler
city: Balassagyarmat
country: Hungary
facility: Ecce Homo Orvosi Bt.
city: Budapest
country: Hungary
facility: Dr. Major Katalin IZOPULM Kft.
city: Budapest
country: Hungary
facility: FOKUSZ-PULMO Egeszsegügyi, Kutatasi, Oktatoi Tanacsado Bt
city: Budapest
country: Hungary
facility: Kineto-Med Bt.
city: Budapest
country: Hungary
facility: Dr. Szabó Gyöngyi
city: Budapest
country: Hungary
facility: Dr. Szilvia Vasas
city: Budapest
country: Hungary
facility: Emósi Bt.
city: Budapest
country: Hungary
facility: Főv.XIX.ker.Önk.Egészségügyi Int
city: Budapest
country: Hungary
facility: Dr. Zoltan Gyula Bende
city: Csitar
country: Hungary
facility: Fenykepzeles KFT
city: Debrecen
country: Hungary
facility: Electro-Medic Bt.
city: Debrecen
country: Hungary
facility: Rizikó '99
city: Dunaújváros
country: Hungary
facility: Szent Pantaleon Hospital
city: Edelény
country: Hungary
facility: Pulmo Bt.
city: Eger
country: Hungary
facility: Dr. Gyetvainé Dr. Lanczki Éva
city: Gyula
country: Hungary
facility: Broncho-Vin BT.
city: Gyula
country: Hungary
facility: Pulmoport Kft.
city: Gyöngyössolymos
country: Hungary
facility: Dr. Kontz Katalin
city: Györ
country: Hungary
facility: Dr. Szász Zoltán
city: Györ
country: Hungary
facility: Györ Tüdögondozo
city: Kaposvár
country: Hungary
facility: Rakvács-Mózes Bt.
city: Komarom
country: Hungary
facility: Selye János Kórház, Rendelőintézet, Tüdőgondozó
city: Miskolc
country: Hungary
facility: Borsod-Abaúj-Zemplén Megyei Központ Kórház és Egyetemi Oktatókórház Semmelweis Tagkórház
city: Monok
country: Hungary
facility: Dr. Bíró Margit
city: Monor
country: Hungary
facility: Monor Szakrendelö Tüdögondozo
city: Mátészalka
country: Hungary
facility: Sz.-Sz.-B. MK és EOK. Mátészalka
city: Nagykozár
country: Hungary
facility: Infer-Med Kft
city: Pécs
country: Hungary
facility: Dr. Varga Ágnes
city: Pócsmegyer
country: Hungary
facility: Ujpesti Szakorvosi Rendelöintezet
city: Siofok
country: Hungary
facility: Dr. Anna Bartha
city: Sopron
country: Hungary
facility: Dr. Breining és Társa Egészségügyi Szolgáltató Bt.
city: Szeged
country: Hungary
facility: Dr. Bánvölgyi Aranka Milassinné
city: Szombathely
country: Hungary
facility: Dr. Geherne Dr. Huszar Hermina Eveline
city: Százhalombatta
country: Hungary
facility: Dr. Radeczky Éva
city: Vásárosnamény
country: Hungary
facility: Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház
city: Ashdod
country: Israel
facility: ASSUTA Ashdod Ltd.
city: Ashkelon
country: Israel
facility: Barzilai Medical Center
city: Bat Yam
country: Israel
facility: Clalit - Bat Yam
city: Beer Sheva
country: Israel
facility: Soroka Medical Center
city: Hadera
country: Israel
facility: Hillel Yaffe Medical Center
city: Haifa
country: Israel
facility: Carmel Medical Center
city: Holon
country: Israel
facility: Edith Wolfson Medical Center
city: Holon
country: Israel
facility: Maccabi Healthcare
city: Jerusalem East
country: Israel
facility: Clalit - Jerusalem East
city: Jerusalem
country: Israel
facility: Shaarei Zedek Medical Center
city: Jerusalem
country: Israel
facility: Research Fund of the Hadassah Medical Organization (R.A.)
city: Kfar Saba
country: Israel
facility: Meir Medical Center Israel
city: Nazareth
country: Israel
facility: Holy Family Hospital
city: Petach Tikva
country: Israel
facility: Rabin Medical Center (Beilinson Hospital)
city: Petach Tikva
country: Israel
facility: Clalit Health Services
city: Rehovot
country: Israel
facility: Kaplan Medical Center
city: Safed
country: Israel
facility: Health Corporation of the Ziv Medical Center (R.A.)
city: Tel Aviv
country: Israel
facility: Clalit - Nazareth
city: Tel Aviv
country: Israel
facility: Clalit - Rishon
city: Tel Aviv
country: Israel
facility: Clalit - Carmiel
city: Tel-Hashomer / Ramat Gan
country: Israel
facility: Sheba Medical Center
city: Tiberias
country: Israel
facility: PORIYA Medical Center
city: Zrifin
country: Israel
facility: Assaf Harofeh MC
city: Kaunas
country: Lithuania
facility: Hospital of Lithuanian University of Health Sciences Kauno klinikos
city: Klaipeda
country: Lithuania
facility: Klaipeda Hospital
city: Klaipėda
country: Lithuania
facility: Enterprise Klaipeda University Hospital
city: Vilnius
country: Lithuania
facility: Vilnius University Hospital Santaros klinikos
city: Vilnius
country: Lithuania
facility: Public Enterprise Vilnius District Central Outpatient Clinic
city: Biała Podlaska
country: Poland
facility: Specjalistyczy Gabinet Lekarski Urszula Świetlik Malesa
city: Białystok
country: Poland
facility: ISPL Beata Kuklińska
city: Bochnia
country: Poland
facility: Poradnia Chorób Płuc Samodzielny Publiczny Zakład Opieki Zdrowotnej"Szpital Powiatowy"W Bochni
city: Bydgoszcz
country: Poland
facility: Indywidualna Praktyka Lekarska Aleksandra Burysz
city: Bydgoszcz
country: Poland
facility: Specjalistyczna Praktyka Lekarska Choroby Płuc Agata Kalicka
city: Chorzów
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska Dr. n. med. Szymon Dworniczak
city: Ciecierzyn
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska Anna Góra-Florek
city: Gdynia
country: Poland
facility: ODM Gdynia
city: Jasło
country: Poland
facility: Specjalistyczna Praktyka Lekarska i USG
city: Jelenia Góra
country: Poland
facility: Specjalistyczny Gabinet Lekarski Juliusz Bokiej
city: Kielce
country: Poland
facility: Niepubliczny Zakład Opieki Specjalistycznej "Zdrowe Płuca"
city: Kielce
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska lek. Krzysztof Lis
city: Koszalin
country: Poland
facility: Specjalistyczny Zespół Gruźlicy i chorób Płuc
city: Końskie
country: Poland
facility: Gabinet lekarski Renata Pejas-Dulewicz
city: Kościan
country: Poland
facility: Gabinet lekarski Wojciech Machowiak
city: Kraków
country: Poland
facility: Poradnia Chorób płuc
city: Kraków
country: Poland
facility: Indywidualna Praktyka Lekarska Aleksander Kania
city: Kraków
country: Poland
facility: Gabinet lekarski Thomasz Mysior
city: Kłomnice
country: Poland
facility: Lekarskie Wizyty Domowe Jarosław Zięba
city: Lublin
country: Poland
facility: Specjalistyczna Praktyka Lekarska Piotr Kamiński
city: Lublin
country: Poland
facility: Alergopneuma sp. Z.o.o.
city: Olmonty
country: Poland
facility: ISPL Łukasz Minarowski
city: Parczew
country: Poland
facility: Prywatny gabinet lakarski Izabela Piętowska-Łazuka
city: Piaseczno
country: Poland
facility: Medycyna-diagnostyka Adam Nowiński
city: Poznań
country: Poland
facility: MEDICAL-MED. Indywidualna Specjalistyczna Praktyka Lekarska Barbara Kuźnar-Kamińska
city: Poznań
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska Magdalena Kostrzewska
city: Proszowice
country: Poland
facility: Poradnia Gruźlicy i Chorób Płuc SPZOZ Proszowice
city: Pyskowice
country: Poland
facility: Gabinet lekarski Roman Masarczyk
city: Płock
country: Poland
facility: Gabinet lekarski Edyta Kozińska
city: Racibórz
country: Poland
facility: Szpital Rejonowy im.dr Rostka-Oddził Pulmonologiczny
city: Rzeszów
country: Poland
facility: Podkarpackie Centrum Chorób Płuc
city: Sieradz
country: Poland
facility: Gabinet lekarski Choroby płuc i oskrzeli Joanna Tęsiorowska
city: Sosnowiec
country: Poland
facility: Indywidualna Specjalistyczna Praktyka Lekarska Krzysztof Filipek
city: Słupsk
country: Poland
facility: NZOZ Poradnia Chorób Płuc i Alergologii
city: Tarnobrzeg
country: Poland
facility: NZOZ Centrum Medyczne SBB
city: Trzebnica
country: Poland
facility: Viltis Medica Spejalistyczan Praktyla Lekarska lek.med. Agata Kot
city: Warsaw
country: Poland
facility: MSWiA
city: Warszawa
country: Poland
facility: STANMED Gabinet Lekarski Robert Staniszewski
city: Warszawa
country: Poland
facility: Instytut Gruźlicy i Chorób Płuc
city: Warszawa
country: Poland
facility: Gabinet lekarski Beata Żołnowska
city: Warszawa
country: Poland
facility: Wizyty Domowe Internisty B. Homola-Piekarska
city: Warszawa
country: Poland
facility: Gabinet lekarski Andrzej Jaworski
city: Wieruszów
country: Poland
facility: Gabinet Internistyczny-Choroby płuc lek.med.M.Kraszewska
city: Wroclaw
country: Poland
facility: Specjalistyczna Praktyka Lekarska dr n.med. Andrzej Obojski
city: Zakopane
country: Poland
facility: Specjalistyczny Szpital Chorób Płuc Odrodzenie im Klary Jelskiej
city: Łódź
country: Poland
facility: Uniwersytecki Szpital Kliniczny Nr 1
city: Łódź
country: Poland
facility: Centrum Leczenia Chorób Płuc w Łodzi
city: Łódź
country: Poland
facility: Przychodnia Specjalistyczna Snzoz Med Med. Sp.Z O.O
city: Arad
country: Romania
facility: DaniPneumoMed SRL
city: Bacau
country: Romania
facility: Butacel F. Maria Danisia - Medic Specialist Pneumolog
city: Bistrița
country: Romania
facility: Manolache Cristina - Medic Specialist Pneumologie
city: Botoșani
country: Romania
facility: Dr. Bendas Magdalena
city: Brasov
country: Romania
facility: Muresan Alina Pneumoconsult Srl
city: Bucharest
country: Romania
facility: Borcea Corina-Ioana Persoana Fizica Autorizata
city: Bucuresti
country: Romania
facility: Dr Cosei Valentin-Caius Pfi
city: București
country: Romania
facility: Ispas Elena-Irina Medic Specialist Pneumolog
city: Constanta
country: Romania
facility: Pneumo Clinic Care SRL
city: Craiova
country: Romania
facility: Crm Pneumology Srl
city: Craiova
country: Romania
facility: Nicolosu Med Srl
city: Focsani
country: Romania
facility: Avencord SRL
city: Iasi
country: Romania
facility: Miron V. Ramona - Medic Colaborator
city: Jud Constanta
country: Romania
facility: Howas Med Srl
city: Jud. Cluj, Mun. Cluj-Napoca
country: Romania
facility: Ciumarnean G Lorena Medic Specialist
city: Jud. Cluj, Mun. Cluj-Napoca
country: Romania
facility: Chis P Ana Florica - Medic Specialist Pneumologie
city: Jud. Giurgiu , Mun. Giurgiu
country: Romania
facility: Cabinet Medical Individual Defta I. Doina-Elisabeta
city: Milcovul
country: Romania
facility: Rarcolmed Srl
city: Mun. Târgu Jiu
country: Romania
facility: Vlad M. Elena - Medic Primar Pneumolog
city: Piatra Neamt
country: Romania
facility: Medic Primar Pneumologie Stoleru Manuela
city: Popesti Leordeni
country: Romania
facility: Raissa Maria Medical Srl
city: Ramnicu-Sarat
country: Romania
facility: PFI Chirea C. Monica Valentina
city: Râmnicu Vâlcea
country: Romania
facility: Viosan-Resp S.R.L.
city: Sat Ariniș
country: Romania
facility: Jager Pneumo Services Srl
city: Sat Visan, Jud Iasi
country: Romania
facility: Sc Nexus Medical Srl
city: Tg.Lăpuș
country: Romania
facility: Cabinet Medical Individual Dr. Butuc Lilia
city: Timisoara
country: Romania
facility: Cabinet Medical Pneumologie Dr. Albu Claudia
city: Vanju Mare
country: Romania
facility: CMI Dr. Mihailescu Constantin
city: Angarsk
country: Russian Federation
facility: Treatment and consultation center
city: Astrakhan
country: Russian Federation
facility: Volga district hospital
city: Astrakhan
country: Russian Federation
facility: Alexander Mariinsky regional clinical hospital
city: Barnaul
country: Russian Federation
facility: Departmental clinical hospital on the station Barnaul of OJSC "RZhD"
city: Barnaul
country: Russian Federation
facility: Barnaul city hospital Nr.5
city: Belgorod
country: Russian Federation
facility: Out-patient hospital "Harmony of health"
city: Bryansk
country: Russian Federation
facility: Bryansk regional hospital No. 1
city: Checkov 2
country: Russian Federation
facility: Chekhov central district out-patient hospital
city: Chelyabinsk
country: Russian Federation
facility: Chelyabinsk regional clinical hospital
city: Chelyabinsk
country: Russian Federation
facility: Road clinical hospital at station Chelyabinsk RRR
city: Chelyabinsk
country: Russian Federation
facility: LLC "AllergoStop", Center of asthma prophylactic and treatment of allergy and asthma
city: Chelyabinsk
country: Russian Federation
facility: Regional Clinical Hospital Nr.3
city: Chelyabinsk
country: Russian Federation
facility: Institution of public health City clinical hospital #11
city: Ekaterinburg
country: Russian Federation
facility: LLC Medical unity "Novaya Bolnitsa
city: Ekaterinburg
country: Russian Federation
facility: Sverdlovsk regional hospital Nr. 2
city: Ekaterinburg
country: Russian Federation
facility: Central city clinical hospital No. 1 of Oktyabrsky district
city: Ekaterinburg
country: Russian Federation
facility: City clinical hospital No. 14
city: Ekaterinburg
country: Russian Federation
facility: Central clinical hospital Nr. 3
city: Ekaterinburg
country: Russian Federation
facility: Medical Association "Novaya Bolnitsa" Polyclinic
city: Ekaterinburg
country: Russian Federation
facility: Central City Hospital Nr.7
city: Irkutsk
country: Russian Federation
facility: Regional oncology dispensary
city: Irkutsk
country: Russian Federation
facility: Irkutsk state clinical hospital Nr.1
city: Irkutsk
country: Russian Federation
facility: East and Siberian institute of medical and ecological studies
city: Iskitim
country: Russian Federation
facility: LLC Pulsar
city: Ivanovo
country: Russian Federation
facility: City clinical hospital No. 4
city: Kaluga
country: Russian Federation
facility: Kaluga regional clinical hospital
city: Kazan
country: Russian Federation
facility: LLC "City Clinical hospital #12"
city: Kazan
country: Russian Federation
facility: Medical Association "Spasenie"
city: Kazan
country: Russian Federation
facility: City clinical hospital Nr. 16
city: Kazan
country: Russian Federation
facility: State autonomy institution of public health
city: Kemerovo
country: Russian Federation
facility: Kemerovo regional clinical phthisiopulmonology medical center
city: Kemerovo
country: Russian Federation
facility: Regional clinical hospital of emergency medical care named after M.A. Podgorbunsky
city: Kirov
country: Russian Federation
facility: LLC "Doctor Lite"
city: Kirov
country: Russian Federation
facility: Kirov clinical and diagnostic centeron the basis of out-patient hospital Nr. 1
city: Krasnodar
country: Russian Federation
facility: Krai clinical hospital Nr. 1 named after prof. S.V. Ochapovskogo
city: Krasnoyarsk
country: Russian Federation
facility: Krai clinical hospital
city: Krasnoyarsk
country: Russian Federation
facility: Krasnoyarsk inter-district clinical hospital Nr. 20 named after I.S. Berzon
city: Kurgan
country: Russian Federation
facility: Kurgan out-patient hospital
city: Kurgan
country: Russian Federation
facility: Kurgan regional clinical hospital
city: Kursk
country: Russian Federation
facility: Out-patient hospital of regional budgetary institution of public health
city: Kursk
country: Russian Federation
facility: Medassist-K
city: Lipetsk
country: Russian Federation
facility: Lipetsk city out-patient hospital Nr. 7
city: Makhachkala
country: Russian Federation
facility: Republican clinical hospital of war and labor veterans
city: Moscow
country: Russian Federation
facility: City out-patient hospital Nr. 22 of department of public health of Moscow, branch Nr. 2
city: Moscow
country: Russian Federation
facility: City out-patient hospital Nr. 134 of department of public health of Moscow
city: Moscow
country: Russian Federation
facility: City out-patient hospital Nr. 52 of department of public health of Moscow
city: Moscow
country: Russian Federation
facility: First Moscow State Medical University named after I. M. Sechenov
city: Moscow
country: Russian Federation
facility: Institution of public health "City out-patient hospital #180 of department of public health of Moscow
city: Moscow
country: Russian Federation
facility: Consultation and diagnostic center Nr. 6 of department of public health of Moscow
city: Moscow
country: Russian Federation
facility: Moscow Regional Research Clinical Institute named after M.F. Vladimirsky
city: Moskau
country: Russian Federation
facility: Educational institution of higher education named after N.I. Pirogov of Ministry of health of Russia
city: Moskau
country: Russian Federation
facility: Moscow scientific and clinical educational center for respiratory medicine
city: Nizhnevartovsk
country: Russian Federation
facility: Nizhnevartovsk county hospital No.2
city: Nizhny Novgorod
country: Russian Federation
facility: Nizhny Novgorod scientific and research institute of sanitary science and occupational pathology
city: Nizhny Novgorod
country: Russian Federation
facility: Privolzhsky Research Medical University
city: Nizhny Novgorod
country: Russian Federation
facility: Nizhny Novgorod city clinical hospital named after N.A. Semashko
city: Novokuznetsk
country: Russian Federation
facility: Novokuznetsk city clinical hospital Nr. 29
city: Novosibirsk
country: Russian Federation
facility: Azbuka zdoroviya
city: Novosibirsk
country: Russian Federation
facility: Road clinical hospital on station Novosibirsk-Main of OJSC "RZhD"
city: Novosibirsk
country: Russian Federation
facility: City clinical hospital No. 2
city: Novosibirsk
country: Russian Federation
facility: Zdorovaya Semiya
city: Novosibirsk
country: Russian Federation
facility: Scientific and research institute of physiology and fundamental medicine
city: Novovsibirsk
country: Russian Federation
facility: City clinical out-patient hospital No. 1
city: Omsk
country: Russian Federation
facility: Clinical medical sanitary station Nr. 7
city: Omsk
country: Russian Federation
facility: City out-patient hospital No. 2
city: Omsk
country: Russian Federation
facility: Multifunctional center of modern medicine "Evromed"
city: Omsk
country: Russian Federation
facility: ZAO "Multifunctional center of modern medicine "Evromed"
city: Orel
country: Russian Federation
facility: City hospital named after S. P. Botkin
city: Orenburg
country: Russian Federation
facility: Orenburg regional clinical hospital No. 2
city: Penza
country: Russian Federation
facility: Penza regional clinical hospital named after N.N. Burdenko
city: Penza
country: Russian Federation
facility: Clinical hospital No. 6 named after G.A. Zakhariyn
city: Perm
country: Russian Federation
facility: City clinical out-patient hospital of Perm
city: Perm
country: Russian Federation
facility: Perm clinical center of federal medical and biological agency "Medical sanitary station #140" on the basis of out-patient hospital #2
city: Perm
country: Russian Federation
facility: City clinical out-patient hospital #2
city: Perm
country: Russian Federation
facility: "City out-patient hospital #7" on the basis of out-patient hospital #2
city: Perm
country: Russian Federation
facility: City clinical out-patient hospital No. 4
city: Perm
country: Russian Federation
facility: Perm regional clinical hospital
city: Petrozavodsk
country: Russian Federation
facility: Hospital of Karelia republic named after V.A.Baranov
city: Podolsk
country: Russian Federation
facility: 1586 military clinical hospital of Ministri of Public Defense
city: Pyatigorsk
country: Russian Federation
facility: Treatment and prophylactic institution of union health resort "Rodnik"
city: Rostov-on-Don
country: Russian Federation
facility: Clinical and diagnostic center "Zdorovie" of Rostov-on-Don
city: Rostov-on-Don
country: Russian Federation
facility: Rostov regional clinical hospital
city: Rostov-on-Don
country: Russian Federation
facility: City clinical hospital No. 20 of Rostov-on-Don"
city: Ryazan
country: Russian Federation
facility: Regional clinical cardiology dispensary
city: Ryazan
country: Russian Federation
facility: Regional clinical hospital
city: Saint Petersburg
country: Russian Federation
facility: Aleksandrovskaya City Hospitel
city: Saint-Petersburg
country: Russian Federation
facility: ZAO "Medi"
city: Saint-Petersburg
country: Russian Federation
facility: LLC "Medical center XXI century" Bryanseva 13"
city: Saint-Petersburg
country: Russian Federation
facility: First Saint-Petersburg state medical university named after acad. I.P.Pavlov
city: Samara
country: Russian Federation
facility: Samara city out-patient hospital No.1
city: Samara
country: Russian Federation
facility: Samara medical and sanitary unit Nr. 5 of the Kirovsky district
city: Samara
country: Russian Federation
facility: City clinical hospital Nr 4 of Samara
city: Samara
country: Russian Federation
facility: Samara city hospital Nr. 13 of Zheleznodorozhny district
city: Samara
country: Russian Federation
facility: Samara city clinical out-patient hospital No.15
city: Sankt Petersburg
country: Russian Federation
facility: City Consultative and Diagnostic Centre Nr. 1
city: Saransk
country: Russian Federation
facility: National Mordovia research state university named after N.P. Ogarev
city: Saratov
country: Russian Federation
facility: Saratov city out-patient hospital Nr. 9
city: Saratov
country: Russian Federation
facility: Saratov city clinical hospital No. 8
city: Saratov
country: Russian Federation
facility: Saratov city out-patient hospital Nr. 10
city: Simferopol
country: Russian Federation
facility: Simferopol city clinical hospital Nr. 7
city: Simferopol
country: Russian Federation
facility: Simferopol clinical hospital
city: Smolensk
country: Russian Federation
facility: Out-patient hospital #5
city: Smolensk
country: Russian Federation
facility: Clinical hospital No. 1
city: St. Petersburg
country: Russian Federation
facility: Institute of Medical Trials
city: Stavropol
country: Russian Federation
facility: Stavropol krai clinical hospital
city: Tambov
country: Russian Federation
facility: Tambov regional clinical hospital named after V.D. Babenko
city: Tolyatti
country: Russian Federation
facility: Tolyatti city hospital Nr. 5
city: Tomsk
country: Russian Federation
facility: Treatment and diagnostic center
city: Tomsk
country: Russian Federation
facility: Out-patient hospital No. 1
city: Tomsk
country: Russian Federation
facility: Tomsk Regional clinical hospital
city: Tomsk
country: Russian Federation
facility: Federal state budgetary institution of SibFNKC FMBA of Russia
city: Tula
country: Russian Federation
facility: City hospital Nr. 9
city: Tver
country: Russian Federation
facility: Regional Clinical Hospital
city: Tyumen
country: Russian Federation
facility: Regional hospital No. 19 Out-patient hospital
city: Ufa
country: Russian Federation
facility: City clinical hospital Nr. 21
city: Ufa
country: Russian Federation
facility: Republican clinical hospital named after G.G. Kuvatov
city: Vladimir
country: Russian Federation
facility: Vladimir Regional clinical hospital
city: Volgograd
country: Russian Federation
facility: Volgograd regional clinical hospital Nr. 1
city: Volgograd
country: Russian Federation
facility: Non-state institution of public health Divisional clinical hospital on station Volgograd-1 of OJSC "RZhD"
city: Voronezh
country: Russian Federation
facility: Institution of public health of Voronezh region "Voronezh regional clinical consultation and diagnostic center"
city: Voronezh
country: Russian Federation
facility: LLC medical center "Diagnostic plus"
city: Yaroslavl
country: Russian Federation
facility: Institution of public health of Yaroslavl region Regional clinical hospital
city: Celje
country: Slovenia
facility: Internistična ambulanta za pljučne in alergijske bolezni Karmen Kramer Vrščaj
city: Kamnik
country: Slovenia
facility: Pulmološka ambulanta dr. Snežana Ulčar Kostič s.p.
city: Kočevje
country: Slovenia
facility: MEDICOINTERNA, medicinske storitve in svetovanje, d.o.o.
city: Kranj
country: Slovenia
facility: VELOG, Zdravstveni center, d.o.o.
city: Kranj
country: Slovenia
facility: Zdravstvene storitve in svetovanje, Tjaša Šubic s.p.
city: Litija
country: Slovenia
facility: Verboten Kopriva Renata - Ordinacija Interne Medicine
city: Ljubljana
country: Slovenia
facility: Arjana Maček d.o.o
city: Ljubljana
country: Slovenia
facility: Kambič-Kafol d.o.o.
city: Ljubljana
country: Slovenia
facility: Medvital Katarina Vukelič s.p.
city: Maribor
country: Slovenia
facility: Alveola, internistični ambulantni diagnostični center d.o.o.
city: Maribor
country: Slovenia
facility: CIIM PLUS, center za interno in interventno medicino, d.o.o.
city: Maribor
country: Slovenia
facility: INTERNIST MB - specialistična ambulantna dejavnost, Marko Bombek s.p.
city: Maribor
country: Slovenia
facility: Zdravstveno svetovanje in storitve, Krstić Zoran, s.p.
city: Murska Sobota
country: Slovenia
facility: Mag. Anton Lopert, dr.med. - Zasebna internistična ambulanta
city: Murska Sobota
country: Slovenia
facility: Zasebna ambulanta za pljučne bolezni, mag. Alojz Horvat, dr. med.
city: Velenje
country: Slovenia
facility: Dr. Ana Novakovic
city: Velenje
country: Slovenia
facility: Dr. med. Tomaz Smonkar
city: Velenje
country: Slovenia
facility: Dr. Mikro Lekic
city: Škofja vas
country: Slovenia
facility: Prim. mag. Šegota Nikša, dr.med., specialistična zdravniška dejavnost, s.p.
city: Basel
country: Switzerland
facility: Gruppenpraxis Basel
city: Frick
country: Switzerland
facility: Gruppenpraxis Frick
city: Geuensee
country: Switzerland
facility: Gruppenpraxis Emmenbrücke
city: Heiligenschwendi
country: Switzerland
facility: Berner Reha Zentrum Medizin Pneumologie
city: Luzern
country: Switzerland
facility: Gruppenpraxis Luzern
city: Utznach
country: Switzerland
facility: Spital Linth
city: Wald
country: Switzerland
facility: Zürcher RehaZentrum Wald
city: Dnipropetrovsk
country: Ukraine
facility: Dnipropetrovsk 6 City clinical Hospital
city: Ivano-Frankivsk
country: Ukraine
facility: Regional centre of Phtysiology and Pulmonology
city: Kharkiv
country: Ukraine
facility: City Clinical Hospital Nr. 13
city: Kyiv
country: Ukraine
facility: National Institute of Phthisiology and Pulmonology named F. G. Yanovsky National Academy of Medical Sciences of Ukraine
city: Lutsk
country: Ukraine
facility: Volyn Regional Clinical Hospital
city: Lviv
country: Ukraine
facility: Lviv Regional Phthisiopneumological Clinical Treatment and Diagnostic Center
city: Vinnitsa
country: Ukraine
facility: Vinnytsia City Clinical Hospital Nr. 1
Study officials:
affiliation: alexey.medvedchikov@boehringer-ingelheim.com
name: Alexey Medvedchikov, +431801057896
role: STUDY_CHAIR
References: