Clinical trial NCT05244863: The Relationship of Muscle Strength With Functional Skills in Geriatric Individuals With Essential Tremor
Official title: The Relationship of Proximal and Distal Muscle Strength With Upper Extremity Functional Skills in Geriatric Individuals With Essential Tremor
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Essential Tremor
Keywords: muscle strength
Geriatric individuals
Functional manual dexterity
Lead sponsor: Kahramanmaras Sutcu Imam University
Sponsor class: OTHER
First posted: 2022-02-17
Enrollment: 80
Sex: ALL
Minimum age (years): 60
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: geriatric individuals with and without tremor

Brief summary: Essential tremor is one of the most common movement disorders in the world and is characterized by postural and/or kinetic tremor.

Although the prevalence studies show differences due to the absence of a biological marker of the disease, it has been shown that the disease affects 4% of the population over 40 years of age and this rate may increase up to 14% in the population over 65 years of age. The annual incidence of Essential Tremor was found to be 616 per 100 thousand.

The incidence of the disease increases with age. An incidence study shows that the disease increases progressively with age, with a sharp increase after age 49. In another study, it was stated that the age of onset of the disease showed a bimodal distribution, reaching the highest level in the second and sixth decades. It is stated that the severity and disability of tremor increase with age. The female-to-male ratio of the disease was found to be equal, but it was shown that more head tremor developed in females.

Although the factors affecting essential tremor are aging, stress, family history, excessive caffeine consumption, smoking, muscle weakness, distal and proximal muscle strength differences were detected in young individuals with tremor. The aim of this study was to investigate the relationship between proximal and distal muscle strength and upper extremity functional skills in geriatric individuals with essential tremor.

Detailed description: In order for many elderly individuals to maintain their independence in functional activities, it is critical that the upper extremity dexterity is at a good level. Because the upper extremity needs to be functional in the realization of social relations such as writing, cooking, combing their hair, brushing their teeth, and participating in recreational activities. Due to the importance of maintaining functional independence in old age, many reviews have attempted to identify primary age-related neuromuscular changes that have an impact on the decreased function of most of the elderly. Age-related declines in function can be explained by increased motor unit firing rate variability of various central and peripheral nervous systems. It is thought to increase tremor in the altered synchronization between motor units in agonist and antagonist muscles, as well as impaired activation between agonist and antagonist muscles. Muscle strength differences in upper extremity functional skills were detected between proximal and distal muscle groups in young individuals with Essential Tremor. In a study investigating the effect of resistance exercise training on tremor in geriatrics, the changes in postural tremor with resistance training in healthy older adults were investigated. In this study; The frequency and severity of tremor of two different groups that received strength and coordination training were evaluated, and it was stated that there was a significant difference in the strength training group.

In this study, which is the only literature study in which strength training was applied to geriatric individuals with essential tremor, it was not specified on which muscle groups the strength training would be effective. In our study, determining the strength differences of the proximal and distal muscle groups of geriatric individuals with essential tremor will enable the creation of effective programs specific to the individual and muscle groups in the rehabilitation program.

Eligibility criteria: Inclusion Criteria:

* Voluntary geriatric individuals aged 60-85 years with and without tremor
* with a mini mental test score above 24,

Exclusion Criteria:

* have diabetic neuropathy
* have undergone hand surgery
* upper and lower motor paralysis
* a history of hand fracture

Primary outcomes:
measure: ahn-Tolosa-Marin Tremor Rating Scale
timeFrame: At baseline
measure: Proximal muscle strength
timeFrame: At baseline
measure: Dİstal muscle strength
timeFrame: At baseline
measure: Disability Arm Shoulder Hand
timeFrame: At baseline
measure: Nine Holes Peg test
timeFrame: At baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Kahramanmaraş
country: Turkey
facility: Kahramanmaraş Sutcu Imam University
Study officials:
affiliation: Kahramanmaras Sutcu Imam University
name: Zekiye İpek Katırcı Kırmacı
role: PRINCIPAL_INVESTIGATOR
References: