Clinical trial NCT05206253: Effectiveness of Egg Versus Whey Protein Powder During Resistance Training
Official title: Egg Versus Whey Protein as the Optimal Supplement for Fitness-conscious People
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Muscle Atrophy
Lead sponsor: University of Saskatchewan
Sponsor class: OTHER
Collaborators: name: Egg Farmers of Canada
First posted: 2022-01-25
Enrollment: 115
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

Detailed description: Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

Eligibility criteria: Inclusion Criteria:

* Resistance training experience for at least one year

Exclusion Criteria:

* Having taken any nutritional supplements the past 30 days
* Currently using anabolic steroids
* Currently taking corticosteroids
* Allergies to dairy or egg products
* Identifying any medical conditions as determined by the "Get Active Questionnaire"

Primary outcomes:
measure: Change in lean tissue mass
timeFrame: 12 weeks
Secondary outcomes:
measure: Change in fat mass
timeFrame: 12 weeks
measure: Change in biceps muscle thickness
timeFrame: 12 weeks
measure: Change in triceps muscle thickness
timeFrame: 12 weeks
measure: Change in quadriceps muscle thickness
timeFrame: 12 weeks
measure: Change in hamstrings muscle thickness
timeFrame: 12 weeks
measure: Change in bench press strength
timeFrame: 12 weeks
measure: Change in leg squat strength
timeFrame: 12 weeks
measure: Change in knee extension strength
timeFrame: 12 weeks
measure: Change in fasting glucose
timeFrame: 12 weeks
Other outcomes:
Locations:
city: Regina
country: Canada
facility: University of Regina
state: Saskatchewan
city: Saskatoon
country: Canada
facility: University of Saskatchewan
state: Saskatchewan
Study officials:
affiliation: University of Saskatchewan
name: Philip Chilibeck, Ph.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Regina
name: Darren Candow, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: