Clinical trial NCT04286022: Specific Neurotechnical Strength Training (NeuroTraining)
Official title: Specific Neurotechnical Strength Training: Randomized Controlled Trial (NeuroTraining)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Neuromuscular Adaptations
Keywords: Strength training
Neuromuscular adaptation
Lead sponsor: University of Malaga
Sponsor class: OTHER
First posted: 2020-02-26
Enrollment: 34
Sex: MALE
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Two randomly allocated parallel groups
Primary purpose: OTHER

Brief summary: This study aims to apply a novel study methodology using high density electromyography (HDEMG) to know what are the mechanisms underlying the structural and functional changes obtained by two different training methods, commonly used, facilitating their understanding, study and subsequent application according to specific needs.

Detailed description: Different training methodologies have previously shown similar results in the improvement of structural or functional characteristics such as hypertrophy or strength. However, the different nature of their methods has suggested for years the possibility that different neuromuscular mechanisms could be behind these observed characteristics.

The development of a new technology, such as high-density electromyography (HDEMG), capable of studying new properties previously hidden from assessment methods, such as the speed of nerve impulse propagation or the frequency of motor unit discharge, has allowed a more thorough study of the mechanisms.

This study aims to apply this new study methodology to know what are the mechanisms underlying the changes at the structural and functional level obtained by two different training methods, commonly used, facilitating their understanding, study and subsequent application according to specific needs.

For this reason, the main hypothesis is the generation of different neuromuscular mechanisms and adaptations by executing, for 4 weeks, two different training methodologies, obtaining a dissociation between the results obtained at the structural level (hypertrophy), functional (generation of strength) and HDEMG analysis of the central and peripheral characteristics of the neuromuscular system in each of the programs studied.

Eligibility criteria: Inclusion Criteria:

* 18-35 years
* men

Exclusion Criteria:

* physical exercise that involves work of upper limbs during the time of the intervention
* upper limb injury during the previous 12 months
* systemic diseases

Primary outcomes:
measure: Change from Baseline Mean Discharge Rate of Brachialis Biceps Motor Units at 4 weeks
timeFrame: Baseline and post-intervention (4 weeks after baseline)
Secondary outcomes:
measure: Speed of propagation of Brachialis Biceps Motor Units
timeFrame: Baseline and post-intervention (4 weeks after baseline)
measure: Isometric force of Brachialis Biceps using hand dynamometer
timeFrame: Baseline and post-intervention (4 weeks after baseline)
measure: Isometric force of Brachialis Biceps using s-beam load cell
timeFrame: Baseline and post-intervention (4 weeks after baseline)
measure: Muscle thickness (thickness) of the brachial biceps using ultrasound
timeFrame: Baseline and post-intervention (4 weeks after baseline)
measure: Arm circumference
timeFrame: Baseline and post-intervention (4 weeks after baseline)
Other outcomes:
Locations:
city: Malaga
country: Spain
facility: Health Science School , University of Malaga
Study officials:
affiliation: University of Malaga
name: Antonio I Cuesta-Vargas, PhD
role: PRINCIPAL_INVESTIGATOR
References: