Clinical trial NCT04418492: An Intervention Targeting Daily Adaptive Skills Through Executive Function Training for Adults With ASD
Official title: An Intervention Program Targeting Daily Adaptive Skills Through Executive Function Training for Adults With Autism Spectrum Disorder: A Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Autism Spectrum Disorder
High-functioning Autism
Autism
Keywords: Autism Spectrum Disorder
High-functioning Autism
Autism
Executive Function
Intervention
Lead sponsor: Seoul National University Hospital
Sponsor class: OTHER
First posted: 2020-06-05
Enrollment: 7
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The current study is a single group pilot study of a novel intervention program which targets improvements in executive functions and adaptive skills in transition age young adults with high-functioning autism spectrum disorder. The main aim of the study is to test the effectiveness of the intervention using a pretest-posttest comparison. It is hypothesised that there will be an increase in executive functions and adaptive skills after the intervention.

Detailed description: The participants engaged in a 10-week group-based intervention program which aims to improve daily adaptive skills based on executive functions and help the transition into adulthood in young adults with ASD. Before and after the intervention, the participants and their parents completed questionnaires that measure executive functions and adaptive skills, and the participants additionally completed an assessment of social adaptive skills. The differences between pre- and post-intervention scores of the outcome measures were analyzed using Wilcoxon signed-rank tests to evaluate the effect of the program.

Eligibility criteria: Inclusion Criteria:

* A clinical diagnosis of ASD as measured by the Autism Diagnostic Observation Schedule and the Autism Diagnostic Interview-Revised
* Full-scale IQ of 70 or above as measured by the Weschler Adult Intelligence Scale

Exclusion Criteria:

* Full-scale IQ less than 70
* Uncooperative and lacking motivation to participate in the programme
* Reporting clinically significant behavioural problems, emotion regulation problems, psychotic symptoms, risk of self-harm or harm to others which can affect the participation to the programme, which is screened by the screening assessments and interviews.

Primary outcomes:
measure: The change in the Korean version of Barkley Deficits in Executive Functioning Scale (K-BDEFS)
timeFrame: 1 week before the intervention, between 5th and 6th session of the intervention and 1-3 week after the intervention.
measure: The change in the Korean version of Vineland Adaptive Behavior Scale-II (K-Vineland-II)
timeFrame: 1 week before the intervention and 1-3 week after the intervention.
measure: The change in the Community Integration Skills Assessment-2 (CISA-2)
timeFrame: 1 week before the intervention and 1-3 week after the intervention.
measure: The change in the Cognitive Flexibility Inventory (CFI)
timeFrame: 1 week before the intervention and 1-3 week after the intervention.
Secondary outcomes:
Other outcomes:
Locations:
city: Seongnam
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
state: Gyeonggi-do
Study officials:
affiliation: Seoul National University Bundang Hospital
name: Hee Jeong Yoo
role: PRINCIPAL_INVESTIGATOR
References: