Clinical trial NCT04654663: Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB
Official title: Impact of Sarcopenia Index on Postoperative Pulmonary Complication in Elderly Patients Undergoing OPCAB: a Retrospective Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Coronary Artery Occlusive Disease
Lead sponsor: Yonsei University
Sponsor class: OTHER
First posted: 2020-12-04
Enrollment: 605
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patients who undersent off-pump coronary artery bypass graft surgery.

Brief summary: Retrospective data collection. The aim of this study is to determine the effect of preoperative sarcopenia index on postoperative pulmonary complications in elderly patients undergoing off-pump coronary artery bypass graft surgery.


Eligibility criteria: Inclusion Criteria:

* Patients who were 65 years of age or older at the time of surgery(off-pump coronary artery bypass graft surgery)
* serum cystatin C and creatinine test results were valid within one week before surgery

Exclusion Criteria:

* Patients with chronic renal failure (estimated glomerular filtration rate less than 60)
* Patients with acute kidney injury
* Patients with respiratory tract infection within 1 month before surgery

Primary outcomes:
measure: postoperative pulmonary complications : pneumonia
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
measure: postoperative pulmonary complications : prolonged ventilation
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
measure: postoperative pulmonary complications : reintubation
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
Secondary outcomes:
measure: postoperative complications : Renal failure
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
measure: postoperative complications : Delirium
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
measure: postoperative complications : Reoperation due to bleeding/tamponade
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
measure: postoperative complications : Permanent stroke
timeFrame: During the hospitalization for surgery. This includes the entire postoperative period up to discharge, even if over 30 days.
measure: postoperative complications : Mortality
timeFrame: During the hospitalization in which the operation was performed, even if after 30 days.
measure: postoperative complications : Mortality
timeFrame: After discharge from the hospital, but before the end of the 30th postoperative day.
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine
Study officials:
affiliation: Severance Hospital
name: Young-Lan Kwak, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: