Clinical trial NCT01305096: Effects of Yoga on Objective and Self-reported Health Indicators Among Female and Male Individuals
Official title: Effects of Yoga on Objective and Self-reported Health Indicators Among Female and Male Individuals
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stress, Psychological, Physiological
Keywords: heart rate variability
oxygen uptake
heart rate recovery
perceived stress
sleep
blood pressure
body mass index
body weight
hand grip strength
sleep quality
subjective health complaints
blood lipids
salivary cortisol
blood sugar
HbA1C
Adiponectin
Leptin
Adipolipoproteins
blood proteins
cytokines
insomnia
sleeplessness
yoga
Lead sponsor: Karolinska Institutet
Sponsor class: OTHER
Collaborators: name: Region Stockholm
name: Stockholm University
First posted: 2011-02-28
Enrollment: 44
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: PREVENTION

Brief summary: The purpose of this study is to determine whether inversions (specific yoga postures in which the heart is higher than the head) and other dynamic and static yoga postures affect heart rate variability, oxygen uptake, blood pressure, blood parameters and other objective measures of health, and a variety of subjective and objective measures of health in female and male individuals in Sweden.

Detailed description: This randomized, controlled trial involving 44 male and females in Sweden will investigate whether yoga inversions and semi-inversions and other dynamic and static yoga postures will affect the following variables: heart rate variability, oxygen uptake, anthropometric variables, common symptoms in general practice, sleepiness, sleep quality and recovery/recuperation after sleep, blood pressure, blood lipids, blood proteins, blood sugar, salivary cortisol, hand grip strength, relaxation and recovery perceived stress, self-rated health, rating of perceived exertion, satisfaction with life, and work-family conflict.

Participants will be divided into an intervention group and a passive control group. The intervention group will participate in six to ten weeks of yoga classes. The classes will be held 1-2 times a week for approximately one hour each and will include yoga poses and breathing techniques. The control group will not participate in any intervention but will conduct their lives as usual.

The variables will be assessed at baseline; at the end of the intervention; and three, six, and twelve months after the end of the intervention.

Eligibility criteria: Inclusion Criteria:

* Aged 20-40 years old

Exclusion Criteria:

* Aged 40 or more years
* Takes medication for high blood pressure or other strong medication
* Recently had an operation
* Diagnosed with eye disease (e.g., glaucoma)
* Diagnosed with depression or burnout syndrome
* Diagnosed with serious back or neck problems
* Participates in intense physical activity more than once a week
* Has digestive problems such as acid reflux
* Serious disorder that affects the ability to do the yoga postures

Primary outcomes:
measure: Change in heart rate variability
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in oxygen uptake
timeFrame: Baseline and at the end of the 8 week intervention
Secondary outcomes:
measure: Change in anthropometric variables
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in common symptoms in general practice
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in level of sleepiness and measures of recovery or recuperation after sleep
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in blood pressure
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in hand grip strength
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in measures of relaxation and recovery
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in perceived stress
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in self-rated health
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in rating of perceived exertion
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in satisfaction with life
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in level of work-family conflict
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in HbA1C
timeFrame: Baseline and at the end of the 8-week intervention
measure: Change in Apolipoproteins
timeFrame: Baseline and after the 8-week intervention
measure: Change in Adiponectin/Leptin ratio
timeFrame: Baseline and at the end of the 8-week intervention
Other outcomes:
Locations:
city: Stockholm
country: Sweden
facility: Karolinska Institute
Study officials:
affiliation: Karolinska Institutet
name: Per Wändell, MD, PhD, Professor
role: STUDY_CHAIR
affiliation: Stockholm University
name: Petra Lindfors, PhD, Professor
role: STUDY_CHAIR
affiliation: Karolinska Institutet
name: Malin Nygren, PhD
role: STUDY_CHAIR
affiliation: Riksidrottsförbundet
name: Lennart Gullstrand, PhD
role: STUDY_CHAIR
References:
citation: Papp ME, Nygren-Bonnier M, Gullstrand L, Wandell PE, Lindfors P. A randomized controlled pilot study of the effects of 6-week high intensity hatha yoga protocol on health-related outcomes among students. J Bodyw Mov Ther. 2019 Oct;23(4):766-772. doi: 10.1016/j.jbmt.2019.05.013. Epub 2019 May 15.