Clinical trial NCT05362097: Analysis of the Reliability and Validity of the Chinese Version of CC-QoL
Official title: Analysis of the Reliability and Validity of the Chinese Version of Child Cough-specific Quality of Life Questionnaire(CC-QoL)
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Chronic Cough
Keywords: reliability validity Cc-QOL
Lead sponsor: Guangzhou Institute of Respiratory Disease
Sponsor class: OTHER
First posted: 2022-05-05
Enrollment: 180
Sex: ALL
Minimum age (years): 7
Maximum age (years): 14
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The childr who conforms to the definition of "Chronic cough in children in the Guidelines for the Diagnosis and Treatment of Chronic Cough in Chinese Children (Revised in 2013)".

Brief summary: At present, there is no research scale designed for the quality of life of children with chronic cough in China, most of them use the cough scale designed for adults to evaluate the quality of life of children. In China, more and more attention has been paid to evaluate and improve the quality of life of children with chronic cough, but cough specific quality of life measurement tools for adults and parents are mostly used, and the Chinese translation version of CQLQ and LCQ is still the main method. There is still no cough specific quality of life measurement tool for children with chronic cough in China. Cc-qol, a specific scale for chronic cough in children, has not been promoted, and no relevant verification of the applicability, validity and reliability of the Chinese version has been found. Therefore, this study aims to verify and compare the applicability, reliability and validity of CC-QOL Chinese version in China through questionnaire survey and follow-up of children with chronic cough.

Detailed description: Descriptive Score: CC-QOL, CET,VAS, Peds-QOL,SCAS and Verbal category Score (VCD); descriptive score: DESCRIPTIVE score; descriptive score: DESCRIPTIVE score; descriptive score: DESCRIPTIVE score; To evaluate the reliability and validity of Cc-QOL in evaluating children's quality of life in China, Compare and analyze Leicester cough questionnaire(LCQ) and child chronic cough-specific quality of life measure Cc-qol was used to evaluate the quality of life in children with chronic cough.

Eligibility criteria: Inclusion Criteria:

* 1.Age 7-14；
* 2.Disease duration \> 4 weeks；
* 3.Spontaneous cough as the main or only clinical symptom。

Exclusion Criteria:

* Chest X-ray was unremarkable, excluding cystic fibrosis, typical asthma or dyspnea, and other underlying diseases.

Primary outcomes:
measure: Validity
timeFrame: At first visit, before medication, 2 weeks and 6 weeks after treatment initiation
measure: Reliability
timeFrame: At first visit, before medication, 2 weeks and 6 weeks after treatment initiation
Secondary outcomes:
measure: Sensitivity
timeFrame: At first visit, before medication, 2 weeks and 6 weeks after treatment initiation
Other outcomes:
Locations:
city: Guangzhou
country: China
facility: Guangzhou institute of respiratory disease
state: Guangdong
Study officials:
References: