Clinical trial NCT06597812: The Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium
Official title: The Effect of Two Different Modes of Anaesthesia Mainantance on Postoperative Delirium in Elderly Patient with Low Preoperative Mini-cog Score
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cognitive Dysfunction, Cognitive Disorder
Delirium - Postoperative
Keywords: delirium
Mini-Cog
anaesthesia
Lead sponsor: Amasya University
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 84
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients over 60 years of age who are scheduled for laparoscopic cholecystectomy

Brief summary: In this study, the cognitive status of the patients in the preoperative period was taken into consideration and the development of delirium after the surgery was investigated. There is no harm to the patient.

Detailed description: The patients were preoperatively assessed for American Society of Anesthesiologists (ASA) risk by an anesthetist and age, sex and comorbidities were recorded. The Mini-cog test was applied as a cognitive screening test by the anesthesiologist in the preoperative period and the test score was recorded. Three-word memory test, clock drawing, and visual function test was performed to evaluate the patient's cognitive functions. In this test, patients were asked to memorize three words such as umbrella, sunshine, and chair at the beginning of the test.

Eligibility criteria: Inclusion Criteria:

* There was a correlation between the incidence of delirium after the age of 60(10).

Exclusion Criteria:

* Patients' age\&lt; 60 years,
* Patients undergoing emergency cholecystectomy or did not have preoperative Mini-Cog assessment,
* With a history of cerebrovaskuler insult that was thought to have an effect on postoperative delirium ,
* Patients with difficulty in cooperation ,
* Patients with hemodynamic instability(arterial blood pressure above 160/90 mmHg and below 90/60 mmHg and patients with pulse rate below 50/min and above 100/min) ,
* Patients with previously diagnosed dementia, and those who had surgical procedures lasting more than 2 hours were excluded from the study.

Primary outcomes:
measure: Group P-S
timeFrame: postoperative 0 1st 2nd hours
Secondary outcomes:
Other outcomes:
Locations:
city: Amasya
country: Turkey
facility: Amasya University Hospital
Study officials:
References:
citation: Fiamanya S, Ma S, Yates DRA. The association between preoperative Mini-Cog(c) score and postoperative delirium (POD): a retrospective cohort study. Perioper Med (Lond). 2022 Apr 21;11(1):16. doi: 10.1186/s13741-022-00249-0.
citation: Jing GW, Xie Q, Tong J, Liu LZ, Jiang X, Si L. Early Intervention of Perioperative Delirium in Older Patients (>60 years) with Hip Fracture: A Randomized Controlled Study. Orthop Surg. 2022 May;14(5):885-891. doi: 10.1111/os.13244. Epub 2022 Apr 19.
citation: Racine AM, Fong TG, Gou Y, Travison TG, Tommet D, Erickson K, Jones RN, Dickerson BC, Metzger E, Marcantonio ER, Schmitt EM, Inouye SK. Clinical outcomes in older surgical patients with mild cognitive impairment. Alzheimers Dement. 2018 May;14(5):590-600. doi: 10.1016/j.jalz.2017.10.010. Epub 2017 Nov 27.