Clinical trial NCT05033665: The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men
Official title: The Impact of Adequate Water Intake on Exercise Performance and Mood in Women and Men
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dehydration
Mood
Lead sponsor: Arizona State University
Sponsor class: OTHER
First posted: 2021-09-05
Enrollment: 217
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Dehydration is defined as the state of water deficit due to excessive water losses and/or small water intake. Underhydration is the result of inadequate water intake leading to activation of water hormonal homeostasis, characterized by elevated vasopressin, lower urinary output, and concentrated urine without any measurable changes in total body water. It is well established that dehydration (water deficit) decreases exercise performance and worsens mood, mainly in women. However, the impact of increased water intake in underhydrated individuals on their exercise capacity and mood is not known.

The aim of the proposed study is to investigate the impact of increased water intake in underhydrated individuals on aerobic exercise performance and mood in both women and men.


Eligibility criteria: Inclusion Criteria:

* Healthy adults
* Residence in Arizona

Exclusion Criteria:

* Use of diuretics
* Use of anti-depressive medication
* Current pregnancy or lactation
* Current use of injectable insulin
* Diagnosed with irritable bowel syndrome
* Do not pass the Physical Activity Readiness Questionnaire for Everyone (PAR-Q) screening

Primary outcomes:
measure: 2-mile run-time (min)
timeFrame: Day 1
measure: 2-mile run-time (min)
timeFrame: Day 8
measure: Mood
timeFrame: Pre-trial on day 1
measure: Mood
timeFrame: Post-trial on day 1
measure: Mood
timeFrame: Pre-trial on day 8
measure: Mood
timeFrame: Post-trial on day 8
measure: Urine osmolality (mmol/kg)
timeFrame: 4 - 8 PM on day 0
measure: Urine osmolality (mmol/kg)
timeFrame: 4 - 8 PM on day 7
measure: Urine osmolality (mmol/kg)
timeFrame: Upon waking (first morning sample) on day 1
measure: Urine osmolality (mmol/kg)
timeFrame: Upon waking (first morning sample) on day 8
measure: Urine specific gravity
timeFrame: 4 - 8 PM on day 0
measure: Urine specific gravity
timeFrame: 4 - 8 PM on day 7
measure: Urine specific gravity
timeFrame: Upon waking (first morning sample) on day 1
measure: Urine specific gravity
timeFrame: Upon waking (first morning sample) on day 8
Secondary outcomes:
measure: Urine color
timeFrame: 4 - 8 PM on day 0
measure: Urine color
timeFrame: 4 - 8 PM on day 7
measure: Urine color
timeFrame: Upon waking (first morning sample) on day 1
measure: Urine color
timeFrame: Upon waking (first morning sample) on day 8
measure: Thirst perception
timeFrame: 4 - 8 PM on day 0
measure: Thirst perception
timeFrame: 4 - 8 PM on day 7
measure: Thirst perception
timeFrame: Upon waking (first morning sample) on day 1
measure: Thirst perception
timeFrame: Upon waking (first morning sample) on day 8
Other outcomes:
Locations:
city: Phoenix
country: United States
facility: Interdisciplinary Science and Technology Building 8
state: Arizona
Study officials:
References: