Clinical trial NCT05773898: Contribution of Psychological Autopsy to the Understanding of Suicidal Behaviors in French Overseas Territories
Official title: Contribution of Psychological Autopsy to the Understanding of Suicidal Behaviors in French Overseas Territories
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Suicide
Mental Disorders
Prognostic Factors
Keywords: Suicide
Psychological autopsies
epidemiology
risk factors
psycholinguistic approach
French overseas territories
Lead sponsor: University Hospital Center of Martinique
Sponsor class: OTHER
Collaborators: name: Department for Research, Studies, Evaluation and Statistics, French Health and Social Affairs Ministry, France
name: French National Institute for Health and Medical Research, MOODS Unit
name: Clinical research and Innovation Office, Martinique
name: SOS KRIZ, Martinique
name: Amiens University Hospital, France
name: Suicide Prevention Resource Center, French Guiana
name: Cayenne Hospital Center, French Guiana
name: University Hospital, La Réunion
name: Tahiti Hospital Center, French Polynesia
name: Regional Health Agency, Martinique
name: Regional Health Agency, French Guiana
name: Regional Health Agency, La Somme
name: Regional Health Agency, La Réunion
First posted: 2023-03-17
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population corresponds to the relatives of a person who died by suicide.

The deceased had been living for at least two years in one of the five study territories and information on cause of death information was obtained from potential sources on suicide victims.

Brief summary: The mains objectives of our project are to coordinate the monitoring of suicides and to identify common or specific suicide risk factors in four overseas DROM-COM (French Polynesia, La Reunion, French Guiana and Martinique) by comparing to a site in mainland France (Amiens). A mixed approach (quantitative and qualitative) will be used, based on semi-directed interviews of the psychological autopsy type.

Detailed description: Epidemiological studies on suicide are rare in Overseas France. Nevertheless, studies conducted independently in New Caledonia (NC) and French Guiana were able to highlight a high prevalence of suicides in minority indigenous populations (Kanaks and Amerindians). These data therefore suggest a socio-cultural variability of suicides within the different territories. Psychological autopsies (used in NC) are an innovative approach that has already proven worldwilde its effectiveness in researching socio-cultural factors and prevalence of mental disorders in suicide subjects (Inserm). However, the qualitative analysis of psychological autopsies, even if it is very complete, is limited to known factors of suicide risk. Given the ethnic specificities of suicidal behavior and the socio-cultural richness of each overseas territory, an exploratory anthropologic approach will make it possible to complete identification of risk factors for suicide or combinations of these specific factors (profiles).

Our project will improve the data collection of suicide cases with the implementation of a network in each site (Public Health Department, Emergency units, Coroner offices, GP, associations, families...). Then interview with proxies of subjects deceased by suicide will allow psychological autopsy (questionnaires SCID to detect mental disorders, Life Trajectories, to detect life events and their burden, Anthropologic for socio-cultural aspects and Psycholinguistic analysis).

The total duration of the project will be 24 months with the recruitment of a maximum of 30 cases per site. Duration of the inclusion period will be 23 months, duration of follow-up per participant 1 month. The follow-up interview will be carried out one month after the inclusion interview. It will make it possible to establish a post-vention of suicide among the bereaved and an evaluation of the impact of the psychological autopsy interviews and the life trajectories of the bereaved.

Eligibility criteria: Inclusion Criteria:

* Persons close of the deceased
* Persons who knew about his/her childhood
* Age 18 or over
* Interviewed for the study between 2 and 11 months after the suicide

Exclusion Criteria:

* People with neuropsychiatric disorders that may affect the quality of the information collected, cognitive (memory and expression) and judgmental functions
* People who refuses to participate
* Persons referred to articles L.1121-6, L.1121-7, L. 1121-8 L.1121-1-2 of the French Public Health Code.

Primary outcomes:
measure: Existence of risk factors and mental disorders evaluated by Structured Clinical Interview for Diagnostic (SCID)
timeFrame: 1 month
Secondary outcomes:
measure: Assessment and comparison of risk factors and mental disorders
timeFrame: 1 month
measure: Existence or not of violence in childhood or during life among suicide cases
timeFrame: 1 month
measure: Score of adversity by the Life Trajectory Questionnaire
timeFrame: 6 month
measure: Existence of language, social and anthropological elements associated with suicide risk factors
timeFrame: 6 month
Other outcomes:
Locations:
city: Fort-De-France
country: Martinique
facility: Centre Hospitalier Universitaire de Martinique - Hôpital Pierre ZOBDA QUITMAN
state: France
Study officials:
affiliation: University hospital, Martinique
name: STEPHANE AMADEO, Pr
role: PRINCIPAL_INVESTIGATOR
References: