Clinical trial NCT01530035: Cardiovascular and Muscular Adaptations to Recreational Soccer and Strength Training in Elderly Healthy 65-75-year-old Men
Official title: Cardiovascular and Muscular Adaptations to Recreational Soccer and Strength Training in Elderly Healthy 65-75-year-old Men
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Adaptation Reaction
Keywords: cardiac
vascular
muscular
adaptations
soccer training
strength training
Lead sponsor: University of Copenhagen
Sponsor class: OTHER
First posted: 2012-02-09
Enrollment: 41
Sex: MALE
Minimum age (years): 65
Maximum age (years): 75
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: A one-year intervention study of 41 healthy elderly men aged 65-75-years.Of these, 24 subjects are untrained men with no regular training activity for the last 5 years. After medical screening and pre-testing, they will be randomized into a football group (n=9), a strength-training group (n=9) or a sedentary control group (n=6). Additional 17 subjects are recruited from local football clubs and have been active football players for the last 40 years. Training will be performed 3x1 hour per week and evaluation will take place after 0, 3 and 12 months. Primary endpoints will be changes in cardiac and vascular structure and function measured by advanced echocardiography (tissue Doppler and speckle tracking imaging), and peripheral arterial tonometry (Endo---PAT device). Secondary endpoints will be evaluation of potential changes in VO2 max, blood pressure, muscle capillaries, lipid profile, circulating catecholamines, body composition, and insulin resistance.


Eligibility criteria: Inclusion Criteria:

* 65-75 year old men
* healthy
* non-smoking
* non-hypertension
* non- cardiac disease

Exclusion Criteria:

* smoking
* cardiac disease
* biomechanical disorders
* cardiac medication

Primary outcomes:
measure: cardiac adaptations
timeFrame: after 16 weeks and one year
Secondary outcomes:
measure: Cardiorespiratory fitness, muscular adaptations, Bloodpressure and Glucose tolerance
timeFrame: after 16 weeks and one year
Other outcomes:
Locations:
city: Copenhagen
country: Denmark
facility: Institute of exercise and sports sciences, university of Copenhagen
Study officials:
affiliation: Institute of exercise and sports sciences, university of copenhagen Denmark
name: Jens Bangsbo, professor
role: STUDY_CHAIR
References:
citation: Andersen TR, Schmidt JF, Pedersen MT, Krustrup P, Bangsbo J. The Effects of 52 Weeks of Soccer or Resistance Training on Body Composition and Muscle Function in +65-Year-Old Healthy Males--A Randomized Controlled Trial. PLoS One. 2016 Feb 17;11(2):e0148236. doi: 10.1371/journal.pone.0148236. eCollection 2016.
citation: Andersen TR, Schmidt JF, Nielsen JJ, Randers MB, Sundstrup E, Jakobsen MD, Andersen LL, Suetta C, Aagaard P, Bangsbo J, Krustrup P. Effect of football or strength training on functional ability and physical performance in untrained old men. Scand J Med Sci Sports. 2014 Aug;24 Suppl 1:76-85. doi: 10.1111/sms.12245. Epub 2014 Jun 5.
citation: Helge EW, Andersen TR, Schmidt JF, Jorgensen NR, Hornstrup T, Krustrup P, Bangsbo J. Recreational football improves bone mineral density and bone turnover marker profile in elderly men. Scand J Med Sci Sports. 2014 Aug;24 Suppl 1:98-104. doi: 10.1111/sms.12239. Epub 2014 Jun 5.
citation: Schmidt JF, Hansen PR, Andersen TR, Andersen LJ, Hornstrup T, Krustrup P, Bangsbo J. Cardiovascular adaptations to 4 and 12 months of football or strength training in 65- to 75-year-old untrained men. Scand J Med Sci Sports. 2014 Aug;24 Suppl 1:86-97. doi: 10.1111/sms.12217. Epub 2014 Jun 5.