Clinical trial NCT06946147: Assessment of Temporomandibular Joint Function Across Different Trimesters of Pregnancy
Official title: Assessment of Temporomandibular Joint Function Across Different Trimesters of Pregnancy
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Temporomandibular; Functional Disturbance
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-04-27
Enrollment: 40
Sex: FEMALE
Minimum age (years): 20
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Twenty pregnant women and twenty non-pregnant women will participate in this study.

Brief summary: This study will be conducted to assess Temporomandibular Joint (TMJ) function across different trimesters of pregnancy.

Detailed description: Pregnancy is a physiological state that can potentially influence the function and biomechanics of the Temporomandibular Joint (TMJ) due to hormonal changes, weight gain, and other associated factors. TMJ disorders are a common problem affecting a significant proportion of the population, with potential impacts on chewing, speaking, and other daily functions, significantly affecting a pregnant woman's quality of life.

Limited research has been conducted to comprehensively evaluate the changes in TMJ function and proprioception (repositioning accuracy) across different trimesters of pregnancy. By identifying and understanding the specific impacts of different trimesters of pregnancy on TMJ function, this study aims to provide insights that can help in the early detection and effective management of TMJ disorders. This, in turn, can improve the overall well-being and comfort of pregnant women, contributing to a more positive pregnancy experience.

Moreover, physiotherapists currently have limited guidelines specifically tailored for managing TMJ dysfunction in pregnant patients. This study aims to fill this gap by providing evidence-based insights into the mechanisms and risk factors associated with TMJ dysfunction during pregnancy. The findings can inform the development of clinical guidelines and therapeutic protocols that address the unique needs of pregnant women, ensuring safer and more effective care.

Eligibility criteria: Inclusion Criteria:

All women will be pregnant with a single baby. Their ages will range from 20 to 35 years old. Their parity will range from 1 to 2. Their body mass index will range from 20 to 30kg2.

Exclusion Criteria:

All women will not suffer from any TMJ disorder or orofacial pain before pregnancy.

All women will not suffer from any severe dental pathology. All women will not suffer from high-risk pregnancy (hyperemesis gravidarum, gestational diabetes).

All women will not suffer from any systemic illnesses.

Primary outcomes:
measure: Mouth Opening (Eyes Open)
timeFrame: 5 months
measure: Mouth Opening (Eyes Closed)
timeFrame: 5 months
measure: Right Lateral Movement (Eyes Open):
timeFrame: 5 months
measure: Right Lateral Movement (Eyes Closed)
timeFrame: 5 months
measure: Left Lateral Movement (Eyes Open)
timeFrame: 5 months
measure: Left Lateral Movement (Eyes Closed)
timeFrame: 5 months
measure: Jaw protrusion (Eyes Open)
timeFrame: 5 months
measure: Jaw protrusion (Eyes Closed)
timeFrame: 5 months
Secondary outcomes:
measure: Assessment of severity of temporomandibular joint dysfunction
timeFrame: 5 months
measure: Assessment of temporomandibular joint pain
timeFrame: 5 months
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Maha Zaghloul mohammed
Study officials:
affiliation: Cairo University
name: HAZEM EL ASHMAWY, Professor
role: STUDY_DIRECTOR
affiliation: Cairo University
name: Doaa Osman, Professor
role: STUDY_CHAIR
References: