Clinical trial NCT01651689: Hair Counts From Vertical and Horizontal Sections of Scalp Biopsy SPecimens in Thai Population With Alopecia
Official title: Hair Counts From Vertical and Horizontal Sections of Scalp Biopsy SPecimens in Thai Population With Alopecia
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Alopecia
Keywords: Scalp biopsy
Hair count
Vertical section
Horizontal section
Thais
Lead sponsor: Siriraj Hospital
Sponsor class: OTHER
First posted: 2012-07-27
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Thai patients who have alopecia and on scadule for hair transplantation

Brief summary: Hair disorders, expecialy scarring alopecia were diagnosed by scalp biopsy specimens in horizontal and vertical sections.(1-4) Data on hair density in Thais are lacking, although in Asians have more fewer hairs than whites.(5-7)Howevery, previous study from East Asian just had only one study and the data was more differently from West Asian and whites. Then this study was performed to evaluate hair density in Thais, and compared to previous study.


Eligibility criteria: Inclusion Criteria:

* Thai
* Age \>= 18 years
* Diagnosis alopecia and on list for hair transplantation in Siriraj hospital

Exclusion Criteria:

* Alopecia areata or positive hair pulling test
* Underlying disease : DM, chronic renal failure, chronic liver disease

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Bangkok
country: Thailand
facility: Siriraj hospital
Study officials:
affiliation: Department of Dermatology, Siriraj hospital, Faculty of Medicine, Mahidol University, Thailand
name: Rattapon Thuangtong, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Elston DM, McCollough ML, Angeloni VL. Vertical and transverse sections of alopecia biopsy specimens: combining the two to maximize diagnostic yield. J Am Acad Dermatol. 1995 Mar;32(3):454-7. doi: 10.1016/0190-9622(95)90068-3.
citation: Elston DM, Ferringer T, Dalton S, Fillman E, Tyler W. A comparison of vertical versus transverse sections in the evaluation of alopecia biopsy specimens. J Am Acad Dermatol. 2005 Aug;53(2):267-72. doi: 10.1016/j.jaad.2005.03.007.
citation: Garcia C, Poletti E. Scalp biopsy specimens: transverse vs vertical sections. Arch Dermatol. 2007 Feb;143(2):268. doi: 10.1001/archderm.143.2.268-a. No abstract available.
citation: Elston DM. Vertical vs. transverse sections: both are valuable in the evaluation of alopecia. Am J Dermatopathol. 2005 Aug;27(4):353-6. doi: 10.1097/01.dad.0000164602.10908.92. No abstract available.
citation: Sperling LC. Hair density in African Americans. Arch Dermatol. 1999 Jun;135(6):656-8. doi: 10.1001/archderm.135.6.656.
citation: Lee HJ, Ha SJ, Lee JH, Kim JW, Kim HO, Whiting DA. Hair counts from scalp biopsy specimens in Asians. J Am Acad Dermatol. 2002 Feb;46(2):218-21. doi: 10.1067/mjd.2002.119558.
citation: Aslani FS, Dastgheib L, Banihashemi BM. Hair counts in scalp biopsy of males and females with androgenetic alopecia compared with normal subjects. J Cutan Pathol. 2009 Jul;36(7):734-9. doi: 10.1111/j.1600-0560.2008.01149.x.