Clinical trial NCT02835963: Acute Heart Failure Study in Patients Admitted to Emergency Department for Dyspnea
Official title: Predictive Criteria of Acute Heart Failure (AHF) in Patients Admitted to Emergency Department for Dyspnea.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Heart Failure
Keywords: acute heart failure
dyspnea
predictive value
Lead sponsor: University Hospital, Toulouse
Sponsor class: OTHER
First posted: 2016-07-18
Enrollment: 342
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The population from which the cohort will be selected is patients admitted to hospital center emergency department of Toulouse, Bordeaux and Pau.

Brief summary: No studies have analyzed the predictive value of different anamnestic and clinical signs for the diagnosis of acute heart failure (AHF) in patients admitted to emergency department. That's why the expert group of the AHF of South West of France mobilizes to conduct this study to evaluate the diagnostic predictive value of different anamnestic and clinical signs for the diagnosis of AHF to emergencies.

Detailed description: There is no recommendation of the French Society of Emergency Medicine (SFMU) on the management of the acute heart failure in the emergency department.

The present study hypothesizes that identifying anamnestic and clinical criteria of AHF in patients admitted to emergency department for acute dyspnea would optimize the management of these patients upon arrival to the emergency department and to implement rapidly the appropriate therapeutic strategies.

All patients admitted for dyspnea will be enrolled by the emergency physicians (after verification of inclusion and exclusion criteria) in the 3 participating centers.

Then, all files will be analyzed retrospectively from information collected by a committee of experts cardiologists and emergency physicians of each center.

The primary objective is the evaluation of diagnostic predictive value of different anamnestic and clinical signs for the diagnosis of AHF in emergency department for the construction of a clinical prediction score of acute heart failure. The secondary objective is the description of the diagnostic and therapeutic management of patients admitted to the emergency for acute dyspnea.

Eligibility criteria: Inclusion Criteria:

* patients ≥ 18 years
* Admitted to emergency department for acute dyspnea

Exclusion Criteria:

* Traumatic dyspnea
* shock / Systolic blood pressure \<90 mmHg

Primary outcomes:
measure: diagnosis of AHF after expertise
timeFrame: 12 months
Secondary outcomes:
measure: Diagnostic and therapeutic management of patients admitted to the emergency for acute dyspnea
timeFrame: Baseline
Other outcomes:
Locations:
city: Bordeaux
country: France
facility: University Hospital
city: Pau
country: France
facility: Hospital
city: Toulouse
country: France
facility: University Hospital Toulouse
Study officials:
affiliation: University Hospital, Toulouse
name: CHARPENTIER Sandrine, MD PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: University Hospital, Toulouse
name: RONCALLI Jérome, MD PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Roncalli J, Picard F, Delarche N, Faure I, Pradeau C, Thicoipe M, Galinier M, Charpentier S. Predictive criteria for acute heart failure in emergency department patients with acute dyspnoea: the PREDICA study. Eur J Emerg Med. 2019 Dec;26(6):400-404. doi: 10.1097/MEJ.0000000000000622.