Clinical trial NCT05891340: Effects of Prehabilitation on Postoperative Recovery
Official title: Effects of Prehabilitation on Postoperative Recovery in Patients Undergoing Lung Resection
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Lung Cancer
Keywords: prehabilitation
quality of recovery
lung resection
Lead sponsor: Istanbul University
Sponsor class: OTHER
First posted: 2023-06-06
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: randomized, prospective
Primary purpose: SUPPORTIVE_CARE

Brief summary: The study to be carried out in the Istanbul Faculty of Medicine Department of Anesthesiology was planned as a randomized, prospective study. Patients who will undergo lung resection will be included in the study.

Patients were randomized into two groups: Intervention Group includes patients who are rehabilitated preoperatively (prehabilitation), Control Group includes patients who are routinely recommended preoperative exercise, alcohol and smoking cessation. Prehabilitation consists of respiratory muscle exercise and walking is recommended to Intervention Group.

Postoperative recovery will be questioned with Quality of Recovery-15 (QoR-15) on the 2nd day and 1st month. The intensive care unit admission, postoperative pulmonary complications and length of hospital stay will be recorded.

Detailed description: The study to be carried out in the Istanbul Faculty of Medicine Department of Anesthesiology was planned as a randomized, prospective study. Patients who will undergo lung resection will be included in the study. Patients will be informed about the study and their written consent will be obtained. Patients who do not give consent will not be included in the study.

Routine preoperative evaluation including detailed history (daily physical activity, clinical complaints at rest or exertion, if any) and physical examination will be performed on the patients. Patients were randomized into two groups: Intervention Group includes patients who are rehabilitated preoperatively (prehabilitation), Control Group includes patients who are routinely recommended preoperative exercise, alcohol and smoking cessation. Preoperative exercise, alcohol and smoking cessation are recommended to all patients. Prehabilitation consists of respiratory muscle exercise with inspiratory muscle trainer (two times a day) and walking (5000steps/day) is recommended to Intervention Group. Hospitalized patients are followed up with daily visits, and patients who are at home are followed up by phone call. All patients' induction of anesthesia and maintenance were similar.

Postoperative recovery will be questioned with Quality of Recovery-15 (QoR-15) on the 2nd day (as primary outcome) and 1st month. The duration of anesthesia, surgery duration, intensive care unit admission, postoperative pulmonary complications and length of hospital stay will be recorded.

Eligibility criteria: Inclusion Criteria:

* ASA physical status classification system score 1-3 patients
* Patients who underwent lung resection
* Patients who agreed to participate in the study and gave written informed consent

Exclusion Criteria:

* Re-operation
* Emergency operations
* Patients with psychiatric drug use
* unability for physical exercise

Primary outcomes:
measure: Quality of recovery at postoperative second day
timeFrame: two days
Secondary outcomes:
measure: Quality of recovery at postoperative first month
timeFrame: one month
measure: length of intensive care unit stay
timeFrame: two weeks
measure: Length of hospital stay
timeFrame: one month
measure: Postoperative pulmonary complications
timeFrame: one month
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Faculty of Medicine
Study officials:
References: