Clinical trial NCT05531851: Effects of Instrument Assisted Soft Tissue Mobilization on Delayed Onset Muscle Soreness
Official title: Effects of Instrument Assisted Soft Tissue Mobilization on Delayed Onset Muscle Soreness
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Musculoskeletal Pain
Soreness, Muscle
Musculoskeletal Disorder
Keywords: Delayed onset muscle soreness, Instrument-assisted soft tissue mobilization, recovery, eccentric exercise
Lead sponsor: Saglik Bilimleri Universitesi
Sponsor class: OTHER
Collaborators: name: Harran University
First posted: 2022-09-08
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized controlled trial
Primary purpose: TREATMENT

Brief summary: The aim of our study is to investigate the effect of instrument assisted soft tissue mobilization therapy on delayed onset muscle soreness

Detailed description: Joint range of motion, pressure pain threshold, edema, isometric muscle strength measurement, visual pain scale, two-point discrimination, biochemical measurements (muscle damage in blood (serum creatine kinase (CC), lactate dehydrogenase (LDH), myoglobin, its effects on aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and biomarkers of inflammation (interleukin-1 beta), Carbonic anhydrase III, and C-reactive protein, and at what time interval and after which treatment session in the process after delayed muscle pain formation. It is aimed to determine how it affects the parameters.

Eligibility criteria: Inclusion Criteria:

1. The participant must be between the ages of 18-35,
2. No fear of needles,
3. Having read and understood the Informed Voluntary Consent Form and agreeing to participate in the study.

Exclusion Criteria:

1. Having neurological or perception problems,
2. Having any cardiovascular, pulmonary and metabolic disease,
3. Any musculoskeletal injury in the last 6 months,
4. Having a history of pain and surgery in the upper extremity,
5. Participating in upper extremity weight training in the last 6 months,
6. Exercise, caffeine and alcohol consumption, and drug use up to 12 hours before the study were determined as

Primary outcomes:
measure: Visual Analogue Scale (VAS)
timeFrame: Four days
measure: Pressure-pain threshold measurement
timeFrame: Four days
measure: Circumference measurement
timeFrame: Four days
measure: Joint range of motion measurement
timeFrame: Four days
measure: Isometric muscle strength
timeFrame: Four days
measure: Two-point discrimination
timeFrame: Four days
measure: Liver enzymes (aminotransferases)
timeFrame: Four days
measure: Creatine kinase
timeFrame: Four days
measure: Lactate dehydrogenase
timeFrame: Four days
measure: Myoglobin
timeFrame: Four days
measure: Interleukin-1 beta
timeFrame: Four days
measure: C reactive protein
timeFrame: Four days
measure: Carbonic anhydrase III
timeFrame: Four days
Secondary outcomes:
Other outcomes:
Locations:
city: Şanlıurfa
country: Turkey
facility: Harran University
Study officials:
affiliation: Harran University
name: İsmail Palalı, PhD (c)
role: PRINCIPAL_INVESTIGATOR
References: