Clinical trial NCT02831153: Evaluation of Emotional Status and Coronary Flow Characteristics by TIMI Frame Count Method
Official title: Effects of Emotional Status on Coronary Flow in Patients Undergoing Coronary Angiography:Multicenter TIMI Frame Count Assessment Study (STRAIN-TIMI Study)
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Coronary Artery Disease
Coronary Artery Ectasia
Slow-Flow Phenomenon
Endothelial Dysfunction
Anxiety
Depression
Lead sponsor: Vascular and Molecular Cardiology Society
Sponsor class: OTHER
Collaborators: name: Abant Izzet Baysal University
name: Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
name: Ankara City Hospital Bilkent
name: Private Yenisehir Hospital
name: Private Gozde Hospital
name: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
First posted: 2016-07-13
Enrollment: 2000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: This study evaluates the effects of emotional status on coronary flow in patients undergoing elective coronary angiography. Patients whom undergoing elective coronary angiography will fulfill the Beck Anxiety Inventory, Beck Depression Inventory, State-Trait Anxiety Inventory, Hospital Anxiety and Depression Scale. State Anxiety Inventory will be fulfilled both before the intervention and after 1 hour the patients learned the results of the coronary angiography. The other scales will be performed after 1 hour the patients learned their results. Coronary flow will be assessed by TIMI (Thrombolysis In Myocardial Infarction) frame count method.


Eligibility criteria: Inclusion Criteria:

* Patients whom planned elective coronary angiography and accept to be included in the study as a participant

Exclusion Criteria:

* \< 18 years, history of prior coronary angiography, history of coronary artery revascularization, acute coronary syndrome patients, atrial fibrillation, heart failure, known systemic diseases

Primary outcomes:
measure: TIMI frame count method analysis
timeFrame: 1 day
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Gulhane Military Medical Academy
state: Kecioren
city: Ankara
country: Turkey
facility: Ankara Numune Training and Research Hospital
city: Ankara
country: Turkey
facility: Ankara Research and Training Hospital
city: Ankara
country: Turkey
facility: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
city: Malatya
country: Turkey
facility: Private Gözde Hospital
city: Mersin
country: Turkey
facility: Private Yenisehir Hospital
Study officials:
References:
citation: Ozturk S, Yalvac HD, Sivri N, Ozturk HM, Kilic Y, Bulut E, Celik A, Barlas Y, Tengiz I, Yetkin E. Anxiety and depression scores in patients with coronary artery disease and coronary artery ectasia. Int J Cardiol. 2015;186:299-301. doi: 10.1016/j.ijcard.2015.03.305. Epub 2015 Mar 20. No abstract available.
citation: Yalvac D, Ozturk S, Sivri N, Kilic Y, Bulut E, Celik A, Barlas Y, Tengiz I, Yetkin E. Effects of patients anxiety and depression scores on coronary flow in patients with normal coronary arteries. Int J Cardiol. 2015 Feb 1;180:55-7. doi: 10.1016/j.ijcard.2014.11.153. Epub 2014 Nov 26. No abstract available.
citation: Yetkin E, Waltenberger J. Novel insights into an old controversy: is coronary artery ectasia a variant of coronary atherosclerosis? Clin Res Cardiol. 2007 Jun;96(6):331-9. doi: 10.1007/s00392-007-0521-0. Epub 2007 Apr 26.