Clinical trial NCT06451965: SCED - Wisdom Enhancement for Post-Stroke Depression
Official title: A Single Case Experiment Design Investigating Wisdom Enhancement to Augment CBT Outcomes for Depression in Post-Stroke Populations
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Post-stroke Depression
Keywords: wisdom
CBT
cognitive behavioural therapy
stroke
depression
Lead sponsor: University of East Anglia
Sponsor class: OTHER
First posted: 2024-06-11
Enrollment: 3
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: One-third of stroke survivors experience post-stroke depression, but there are currently no official guidelines for supporting them. Researchers aim to investigate whether the wisdom enhancement timeline technique can reduce depression in stroke survivors. The investigators also want to understand how this technique positively impacts mood, identity, self-esteem, and wisdom. The study will involve nine stroke survivors from the National Health Service (NHS) to gain insights into effective ways to support those with post-stroke depression.

Detailed description: One-third of stroke survivors have post-stroke depression. Finding ways to help them feel more positive after such a challenging event can be tricky. Right now, there are no official guidelines on the best way to support post-stroke depression, and research into this is still growing. That is why the investigators want to see if the wisdom enhancement timeline can improve the mood and overall well-being of people who have had a stroke.

In this study, the investigators have two goals. First, the investigators want to see if the wisdom enhancement timeline technique can reduce depression in stroke survivors. Second, the investigators aim to discover how this technique brings positive mood changes.

The main question the investigators want to answer

1. Does enhancing wisdom through the timeline technique improve psychological outcomes (mood, identity, self-esteem) in post-stroke depressed individuals?
2. In post-stroke depressed individuals, is the improvement in wisdom the first indicator of subsequent improvements in identity, self-esteem, and mood?

It is hypothesised that wisdom will improve first following the session where wisdom is applied. This will then be followed by either identity or self-esteem, with mood improving last.

To carry out this study, the investigators will work with three stroke survivors receiving care from the National Health Service (NHS). By focusing on this smaller group, the investigators hope to gain insights into the effectiveness of the technique in reducing depression and enhancing the lives of stroke survivors. This study is essential as it could help the investigators understand the best way to support those with post-stroke depression.

Eligibility criteria: Inclusion Criteria:

* Had a stroke.
* Those who self-report as having difficulties with depression to a clinician.
* Have sufficient cognitive and communication abilities for informed consent and active engagement

Exclusion Criteria:

* Under the age of 18. Because this is the age when they are treated as an adult by UK law.
* Severe cognitive impairments or mental health difficulties that would hinder task engagement or provide informed consent.
* Medical instability jeopardising consistent participation or well-being.
* Significant risk concerns regarding safety to themselves or others.
* Substance use/dependency impacting adherence.
* Prescribed psychotropic medication less than 3 months ago.
* Currently involved in research.

Primary outcomes:
measure: Visual Analogue Scale (VAS)
timeFrame: Daily from baseline to the end of the 10-week study.
Secondary outcomes:
measure: Patient Health Questionnaire-9
timeFrame: Assessed at baseline and at the end of the 10-week study.
Other outcomes:
Locations:
city: Norwich
country: United Kingdom
facility: University of East Anglia
Study officials:
References: