Clinical trial NCT06203535: Effect of Aerobic Training on Quality of Life in Elderly With Idiopathic Chronic Fatigue
Official title: Effect of Aerobic Training on Quality of Life in Elderly With Idiopathic Chronic Fatigue
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Chronic Idiopathic Fatigue
Keywords: aerobic training
Lead sponsor: Pharos University in Alexandria
Sponsor class: OTHER
First posted: 2024-01-12
Enrollment: 40
Sex: ALL
Minimum age (years): 60
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: the study was conducted to evaluate the effectiveness of aerobic training for decreasing fatigue severity and increasing quality of life in elderly with idiopathic chronic

Detailed description: idiopathic chronic fatigue (ICF) or chronic idiopathic fatigue (CIF), this type of tiredness is ongoing and unrelated to any underlying medical or mental health issues. Different diagnostic criteria apply to people with idiopathic chronic fatigue and those with chronic fatigue syndrome (CFS).

Regular aerobic exercise has been demonstrated to improve cardiopulmonary fitness, increase physical activity levels, and decrease the degree of fatigue in elderly patients with severe idiopathic fatigue.

Eligibility criteria: inclusion criteria:

* ages ranged from 60 to 70 years and they will have BMI in between25.0-29.9 kg/m2,
* complaining fatigue least six months ago without identifying any specific cause for their fatigue.
* could walk safely without the aid of another person.

Exclusion Criteria:

* Renal, vascular, hepatic, autoimmune, heart, chest and thyroid disorders.
* Lower limb arthritis or any orthopedic problem will hinder the training.
* Cognitive impairment or psychological problems,
* fatigue caused as a known side effect of medication.
* any febrile condition and/or infectious diseases

Primary outcomes:
measure: Older People's Quality of Life Questionnaire (OPQOL-brief):
timeFrame: 2 monthes will take pre and post total study peroid
measure: fatigue severity assessment scale
timeFrame: 2 month will take pre and post total study peroid
measure: six mints walk test
timeFrame: 2 monthes will take pre and post total study peroid
measure: Glutathione blood test:
timeFrame: 2 monthes will take pre and post total study peroid
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Chen FT, Etnier JL, Chan KH, Chiu PK, Hung TM, Chang YK. Effects of Exercise Training Interventions on Executive Function in Older Adults: A Systematic Review and Meta-Analysis. Sports Med. 2020 Aug;50(8):1451-1467. doi: 10.1007/s40279-020-01292-x.
citation: Hendriks C, Drent M, Elfferich M, De Vries J. The Fatigue Assessment Scale: quality and availability in sarcoidosis and other diseases. Curr Opin Pulm Med. 2018 Sep;24(5):495-503. doi: 10.1097/MCP.0000000000000496.
citation: Bowling A, Hankins M, Windle G, Bilotta C, Grant R. A short measure of quality of life in older age: the performance of the brief Older People's Quality of Life questionnaire (OPQOL-brief). Arch Gerontol Geriatr. 2013 Jan-Feb;56(1):181-7. doi: 10.1016/j.archger.2012.08.012. Epub 2012 Sep 19.