Clinical trial NCT03949868: Mindful Attention to Variability in Everyday Memory
Official title: Mindful Attention to Variability in Everyday Memory
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Memory Lapse
Keywords: mindfulness
forgetfulness
Langerian mindfulness
Lead sponsor: Harvard University
Sponsor class: OTHER
First posted: 2019-05-14
Enrollment: 210
Sex: ALL
Minimum age (years): 65
Maximum age (years): 80
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: BASIC_SCIENCE

Brief summary: Forgetfulness is a common complaint among middle and older adults, with the vast majority of these complaints not rooted in established causes or diagnoses. The contents of these subjective cognitive complaints (SCC) include difficulty retrieving specific words (e.g., names of people or places), misplacing common items (e.g., keys or eyeglasses), and prospective memory failures (e.g., forgetting appointments and reasons for entering a room). One study found that 54% of people in a sample composed of 15,000 adults over the age of 55 reported that they had some difficulty remembering things over the past year. In the subsample composed of individuals aged 85+, this figure increased to 62%.

While some experiences of forgetting can be partially explained by age-related cognitive decline, problems with retrieval processes can be attributed to a host of other factors including stress and anxiety, lack of sleep, and side effects from medications. Even with all of these other possible aspects at play, older adults tend to attribute everyday instances of forgetting to uncontrollable factors including age. Moreover, while society tends to associate forgetting with the elderly population, young adults also report the experience of forgetting. There is reason to suspect that while older adults tend to experience more instances of forgetting than they did as younger adults, they also pay more attention to instances of forgetting, gathering evidence that they are declining. Every instance of forgetting can confirm that one is in the midst of decline. This process is a type of confirmation bias: Every time an older adult notices an instance of forgetting, he/she confirms that the self fits within the larger negative age stereotype. The present study investigates the Attention to Variability Paradigm. Specifically the participants will pay attention to how memory performance fluctuates throughout the day. Primary outcomes will be memory efficacy beliefs and memory performance on a telephone task.

Detailed description: In the present study, the participants will be assigned to one of three groups: an active control group, a group asked to attend to everyday memory performance, and a group asked to notice variability in their everyday memory performance. The researchers hypothesize that the experimental groups will improve on memory outcomes more than those in the control group as a result of participation. The researchers hypothesize that when older adults are trained over 6 days to notice variability in memory ability the participants will report having more control over memory abilities then will the participants in the other two groups. The researchers also expect that the participants will show more improvement on a memory task than the participants in the other groups.

The researchers will take measurements of memory efficacy beliefs and memory performance at 2 timepoints (T0=baseline, T1= immediately after the 6 days of text messages). All surveys will be collected online via the Qualtrics.com platform.

Eligibility criteria: Inclusion Criteria:

* Age: 65-80
* An expressed concern or anxiety about memory performance (Responding "YES" when asked if concerned about memory at all)
* Fluent in English
* Owns a smartphone

Exclusion criteria:

* The presence of cognitive impairment (more than 2 incorrect responses) on the Short Portable Mental Status Questionnaire (SPMSQ), an instrument developed to assess cognitive functioning over the phone.
* The presence of any medical conditions that affect cognitive ability, such as stroke, acquired brain injury, dementia, and other neurological disorders or illnesses, or untreated hypertension.

Primary outcomes:
measure: Everyday Memory Questionnaire-Revised (EMQ-R; Royle & Lincoln, 2008)
timeFrame: 2 minutes
measure: Memory Controllability Inventory (MCI; Lachman, Bandura, Weaver, & Elliott, 1995)
timeFrame: 3 minutes
measure: Multifactorial Memory Questionnaire (MMQ; Troyer & Rich, 2002).
timeFrame: 3 minutes
measure: Brief Test of Adult Cognition by Telephone with Stop-and-Go Switch Task (BTACT; (Tun & Lachman, 2006)
timeFrame: 20 minutes
Secondary outcomes:
measure: Langer Mindfulness Scale (LMS-14; Pirson, Langer, Bodner, & Zilcha, 2012)
timeFrame: 2 minutes
measure: Positive and Negative Affect Schedule (PANAS; Watson, Clark, & Tellegen, 1988)
timeFrame: 2 minutes
measure: Image of Aging Scale (Levy, Kasl, & Gill, 2004).
timeFrame: 2 minutes
measure: Subjective Age Measure (Barak & Schiffman, 1981).
timeFrame: 2 minutes
Other outcomes:
Locations:
city: Cambridge
country: United States
facility: Harvard University
state: Massachusetts
Study officials:
References: