Clinical trial NCT05493787: Nudging Flu Vaccination by Making it Easy for Patients to Schedule a Flu Shot
Official title: Nudging Flu Vaccination by Making it Easy for Patients to Schedule a Flu Shot
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Influenza
Keywords: Vaccination
Health promotion
Health behavior
Economics, Behavioral
Lead sponsor: Geisinger Clinic
Sponsor class: OTHER
Collaborators: name: Massachusetts Institute of Technology
name: National Bureau of Economic Research, Inc.
First posted: 2022-08-09
Enrollment: 139503
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purpose of this study is to test whether messages that make it easy to schedule a flu shot appointment will increase flu shot rates in patients without an upcoming appointment. The study will also test which message versions and message timing are most effective for increasing flu vaccination.

Detailed description: The CDC recommends a flu vaccination to everyone aged 6+ months, with rare exception; almost anyone can benefit from the vaccine, which can reduce illnesses, missed work, hospitalizations, and death. Past work from the study team focused on encouraging flu shots for patients with upcoming appointments. However, many patients in the health system do not have any appointments during flu season.

Eligible patients without an upcoming appointment will be randomized to a passive control group (no message), an active control group (a basic message stating that the patient can get a flu shot at Geisinger) or one of several other messages informed by behavioral science ("ease", "waiting for you", "protect yourself - rare outcomes", or "protect yourself - frequent outcomes"). Patients will be randomly assigned to one of several message send dates. Messages sent via patient portal, short message service (SMS) text, email, and/or another modality, will include a link redirecting patients to a page where they can self-schedule a flu shot.

Eligibility criteria: Inclusion Criteria:

* Included in one or both of the following two base patient lists:

  1. Geisinger patient portal flu outreach list for Fall 2022
  2. A list of patients obtained from Geisinger's Phenomics and Clinical Data Core (PACDC). This list will include active Geisinger patients (all patients on this list attended at least one primary care appointment at Geisinger between 10/1/2008 and 4/13/2022, and either had a Geisinger primary care provider assigned as of April 2022, or were in the Electronic Health Record \[EHR\] since at least September 2021 and had at least one encounter in 2020-2022).
* Aged 18 or older as of October 2022
* Has had a Geisinger encounter in the last 2 years as of October 2022
* Either of the following, as of October 2022:

  1. Has a Geisinger PCP assigned in the Community Medicine, Pediatrics, or Internal Medicine service line
  2. In the last 2 years, has completed an appointment in a Geisinger specialty on a list of specialties approved by system leadership for flu shot communications
* Has not received a flu-shot during the 2022-23 flu season as of \~1 week prior to the message date (timeline may be slightly different, depending on data pull logistics), according to the Electronic Health Record (EHR)
* Does not have a scheduled in-person primary care or in-person flu-shot-eligible specialty appointment in the 12 weeks following their assigned message send date, as of \~1 week prior to the message date (timelines may be slightly different, depending on data pull logistics or clinical guidance)

  * As of this writing, the team plans to define a flu-shot-eligible specialty appointments as appointments in departments that have historically documented or administered flu vaccine. However, this approach may change slightly based on changing clinical guidance.

Exclusion Criteria:

* The CMSL/Marketing list will include patients in Geisinger's 65Forward or Community Care populations. If necessary due to logistical constraints, we may exclude these 65Forward and/or Community Care patients from our study.
* Cannot be contacted via the communication modality being used in the study (e.g., patient portal, SMS), e.g., due to insufficient/missing contact information in the EHR or because they opted out
* Has an allergy to flu vaccines according to any EHR allergy table known to the study team
* Has a health maintenance modifier indicating they are permanently discontinued from receiving a seasonal flu shot
* Is on a list of dismissed patients

Primary outcomes:
measure: Number of Patients Who Self-scheduled a Flu Shot
timeFrame: Within 4 weeks of message send date
Secondary outcomes:
measure: Flu Vaccination
timeFrame: Within 4 weeks of message send date
Other outcomes:
measure: High Confidence Flu Diagnosis
timeFrame: Up to 7 months
measure: "Likely Flu" Diagnosis
timeFrame: Up to 7 months
measure: Flu Complications
timeFrame: Up to 10 months
measure: ER Visits
timeFrame: Up to 10 months
measure: Hospitalizations
timeFrame: Up to 10 months
measure: COVID-19 Vaccination Rates
timeFrame: Up to 7 months
measure: Number of Patients Who Self-Scheduled a Flu Shot by Sex
timeFrame: Within 4 weeks of the message send date
measure: Number of Patients Who Self-Scheduled a Flu Shot by Race
timeFrame: Within 4 weeks of the message send date
measure: Number of Patients Who Self-Scheduled a Flu Shot by Ethnicity
timeFrame: Within 4 weeks of the message send date
Locations:
city: Danville
country: United States
facility: Geisinger Clinic
state: Pennsylvania
Study officials:
affiliation: Geisinger Clinic
name: Christopher F Chabris, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Geisinger Clinic
name: Michelle N Meyer, PhD JD
role: PRINCIPAL_INVESTIGATOR
References: