Clinical trial NCT05547204: Impact of Coffeeberry Extract on Skill Performance During Simulated Match Play in Academy Football Players
Official title: Impact of Coffeeberry Extract on Skill Performance During Simulated Match Play in Academy Football Players
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Skill Performance
Soccer Performance
Coffeeberry Effects
Keywords: coffeeberry
caffeine
polyphenols
chlorogenic acid
exercise
soccer
football
skill
performance
Lead sponsor: PepsiCo Global R&D
Sponsor class: INDUSTRY
First posted: 2022-09-21
Enrollment: 15
Sex: ALL
Minimum age (years): 16
Maximum age (years): 28
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: This study of soccer skill performance has three objectives:

1. Compare effects of coffeeberry (300mg) and placebo ingestion on dribbling speed and precision, passing speed and accuracy, and sprint speed during a full simulated soccer match.
2. Compare effects of coffeeberry (300mg) and placebo ingestion on subjective measures (mental / physical energy and activation-deactivation (feelings or mood) during a full simulated soccer match.
3. Compare effects of coffeeberry (300mg) and placebo ingestion on chlorogenic acid (CGA) and caffeine metabolites in the blood 1-hour post ingestion, and other blood metabolites (glucose/lactate) throughout the simulated soccer match.


Eligibility criteria: Inclusion Criteria:

* Provide valid informed consent prior to any study procedure
* Male soccer players age 16 to 28 years.
* \>= 5-year soccer playing experience
* \>= 1-year regularly soccer training
* Free of injuries
* Willing to avoid alcohol in the 48-h period prior to all visits
* Willing to avoid caffeinated products and apples, berries/cherries for 24-h prior to all visits
* Willing to record food intake over the 48-h period prior to the first trial and replicate for second trial
* Willing to abstain from strenuous physical activity for 24-h before all visits

Exclusion Criteria:

* Smoking
* Cardiovascular diseases
* Diabetes or other metabolic disease • Hypertension (\>140/\>90 mm Hg)
* Presence of injuries
* Major illnesses or surgery in prior 90 days
* Participation in another clinical trial in the past month

Primary outcomes:
measure: Dribbling speed
timeFrame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
measure: Dribbling precision
timeFrame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
measure: Passing accuracy
timeFrame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match.
measure: Passing speed
timeFrame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
measure: Sprint speed.
timeFrame: Change from pre-dose baseline through end of match 3.5 hours post consumption at multiple intervals each half of match
Secondary outcomes:
measure: Blood analyte: Chlorogenic acid (CGA)
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Blood analyte: Caffeine metabolites
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Blood analyte: Glucose
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Blood analyte: Lactate
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Rating of perceived exertion (RPE)
timeFrame: Half-time and end of match (3.5 hours)
measure: Activation-deactivation (feelings or mood)
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Mental energy
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Physical energy
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Gut comfort
timeFrame: Pre-dose baseline, 60 minutes post-dose, half-time, and end of match (3.5 hours)
measure: Heart rate
timeFrame: Continuous from pre-dose baseline through end of match (3.5 hours)
measure: Hydration status
timeFrame: Pre-dose baseline and end of match (3.5 hours)
Other outcomes:
Locations:
city: Stirling
country: United Kingdom
facility: U. Stirling, Health Science and Sport
state: Scotland
Study officials:
affiliation: U. Stirling, Scotland
name: Stuart Galloway, PhD
role: PRINCIPAL_INVESTIGATOR
References: