Clinical trial NCT05507281: Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Thoracotomy
Official title: Efficacy of Ultrasound-guided Erector Spinae Plane Block Versus Retrolaminar Block for Postoperative Analgesia in Patients Undergoing Thoracotomy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Postoperative Analgesia
Retrolaminar Block
Ultrasound-guided Erector Spinae Plane Block
Thoracotomy
Lead sponsor: Tanta University
Sponsor class: OTHER
First posted: 2022-08-18
Enrollment: 60
Sex: ALL
Minimum age (years): 21
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Patients were randomly allocated into 3 equal groups (Control group, Ultrasound-guided Erector Spinae Plane Block group, Retrolaminar Block, 20 patients each) through sealed envelopes.
Primary purpose: TREATMENT

Brief summary: Comparing efficacy of Ultrasound-guided Erector Spinae Plane Block versus Retrolaminar Block for Postoperative Analgesia in Patients Undergoing Thoracotomy

Detailed description: Thoracotomy is one of the most painful surgical procedures. The reported incidence of persistent pain after thoracic surgery (post thoracotomy pain syndrome) has been reported in 20%-70% of patients. Inadequately treated post thoracotomy pain can have several negative consequences. Therefore, pain relief is essential to facilitate coughing and deep breathing and to promote early mobilization.

Thoracic epidural analgesia and thoracic paravertebral block are strongly recommended techniques for managing post thoracotomy pain to reduce opioid use and the related adverse effects as hypoventilation, depression of cough reflex, nausea and vomiting. However, they can be technically challenging to perform and are associated with up to 15% failure rate in Thoracic epidural analgesia and potential risk of pneumothorax in thoracic paravertebral block.

Erector spinae plane block is a relatively novel ultrasound-guided regional technique. Its application in patients with chronic thoracic neuropathic pain and acute surgical pain has been described by Forero et al.

Retrolaminar block is an easy and safe analgesic technique. It has been reported to be satisfactory for post-operative analgesia after breast surgery.

To our knowledge there is no clinical studies, comparing the effectiveness of both blocks on postthoracotomy pain, has been reported.

Eligibility criteria: Inclusion Criteria:

* Adult patients aged 21-65 years old of both sexes.
* Patients were scheduled for elective thoracotomy.
* Their ASA physical status classification is II-III.

Exclusion Criteria:

* Patients' refusal.
* Local infection at the site of block.
* Coagulation abnormalities.
* Sever spinal deformity e.g. scoliosis.
* Known hypersensitivity to local anesthetics.
* Mental dysfunction and cognitive disorders.
* History of drug abuse and chronic analgesic use.

Primary outcomes:
measure: Pain assessment
timeFrame: 24 hours postoperatively.
Secondary outcomes:
measure: The time of first analgesic request
timeFrame: 24 hours postoperatively
measure: The total amount of morphine
timeFrame: 24 hours postoperatively
Other outcomes:
Locations:
city: Tanta
country: Egypt
facility: Tanta University
state: Gharbia
Study officials:
References: