Clinical trial NCT03831139: Cultural Adaptation of the TIM&SARA Prevention Program
Official title: What Makes Prevention Work? Cultural Adaptation of an Effective Program for African-American Adolescents
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Depressive Symptoms
Lead sponsor: University of Louisville
Sponsor class: OTHER
First posted: 2019-02-05
Enrollment: 740
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Disparities between African-American and European-American youth regarding academic outcomes, mental health, and physical health exist. Depression, a very common mental health problem, plays a central role by impacting academic outcomes and cardiovascular health. Thus, a program that successfully reduces the likelihood for youths to develop depression should also reduce problems with academic outcomes and physical health and therefore reduce disparity in all three domains. Research demonstrates that European-American youth benefit more from programs preventing the development of depression than their African-American peers. Thus, the goals of this project are to (a) identify mechanisms that may result in differential program effectiveness across racial groups, and (b) adapt such a program (TIM\&SARA) so youth from diverse racial backgrounds benefit similarly. Freshmen in an urban high-school will participate in TIM\&SARA, fill out surveys and give biological data in saliva.

Detailed description: Already in adolescence, substantial disparities between African-Americans and European-Americans regarding academic outcomes, mental health, and physical health like cardiovascular health exist. While these domains are often treated as unrelated, they influence each other in a way that the disparity in one variable increases the likelihood for disparity in the others. Depression, a very common mental health problem, plays a central role by impacting academic outcomes and cardiovascular health. Thus, a program that successfully reduces the likelihood for youths to develop depression should also reduce problems with academic outcomes and physical health and therefore reduce disparity in all three domains. Unfortunately, research demonstrates that European-American youth benefit more from programs preventing the development of depression than their African-American peers. Thus, the main goals of this research project are to (a) identify mechanisms that may result in differential prevention program effectiveness across youth race groups, and (b) adapt such a program (TIM\&SARA) so youth from diverse racial backgrounds benefit similarly.

In this project, the depression prevention program TIM\&SARA will be implemented as part of the normal school curriculum for freshmen in an urban high-school. The differential effects of the program on African-American and European-American youths will be examined using surveys and biological data in saliva.

Eligibility criteria: Inclusion Criteria:

* 9th grade students in the participating high school

Exclusion Criteria:

-

Primary outcomes:
measure: Center for Epidemiological Studies - Depression Scale (CES-D)
timeFrame: 5 minutes
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: University of Louisville
name: Patrick Possel, Dr.rer.soc.
role: PRINCIPAL_INVESTIGATOR
References: