Clinical trial NCT05638035: Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women
Official title: Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Sarcopenic Obesity
Sarcopenia
Obesity
Lead sponsor: Kutahya Health Sciences University
Sponsor class: OTHER
First posted: 2022-12-06
Enrollment: 1
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The population of the research consists of voluntarily non-obese women residing in Kütahya/Center and obese women voluntarily participating in the study at Kütahya Evliya Çelebi Training and Research Hospital Physical Therapy and Rehabilitation Hospital Obesity School.

Brief summary: Research; It is a planned, non-invasive, controlled study in obese female volunteers and non-obese female volunteers. The population of the study consists of voluntarily non-obese women and obese women. Sarcopenia assets of individuals will be measured with the sarc-f questionnaire, and then muscle strength, muscle mass and physical performance tests will be measured. Then, rectus femoris muscle thickness will be measured with USG, and then walking and balance will be measured with ZEBRIS.


Eligibility criteria: Inclusion Criteria:

* Being over 18 years old and female
* Volunteering and accepting to participate in the study
* BMI 30-39.9 kg/m2 in obese women (experimental group)
* BMI 18-27.9 kg/m2 in non-obese women (control group)
* Not having cardiorespiratory, neurological, orthopedic and metabolic disorders

Exclusion Criteria:

* Being under 18 years old and male
* Having a BMI of 40.0 kg/m2 and above in obese women (experimental group)
* BMI 28.0 kg/m2 and above in non-obese women (control group)
* Having cardiorespiratory, neurological, orthopedic and metabolic disorders

Primary outcomes:
measure: Rectus femoris muscle thickness
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Kütahya
country: Turkey
facility: Kütahya Health Sciences University
state: Centre
Study officials:
affiliation: kütahya health sciences university
name: yagmur kuralay
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mueller N, Murthy S, Tainter CR, Lee J, Riddell K, Fintelmann FJ, Grabitz SD, Timm FP, Levi B, Kurth T, Eikermann M. Can Sarcopenia Quantified by Ultrasound of the Rectus Femoris Muscle Predict Adverse Outcome of Surgical Intensive Care Unit Patients as well as Frailty? A Prospective, Observational Cohort Study. Ann Surg. 2016 Dec;264(6):1116-1124. doi: 10.1097/SLA.0000000000001546.
citation: Dutil M, Handrigan GA, Corbeil P, Cantin V, Simoneau M, Teasdale N, Hue O. The impact of obesity on balance control in community-dwelling older women. Age (Dordr). 2013 Jun;35(3):883-90. doi: 10.1007/s11357-012-9386-x. Epub 2012 Feb 10.
citation: Ates Bulut E, Soysal P, Dokuzlar O, Kocyigit SE, Aydin AE, Yavuz I, Isik AT. Validation of population-based cutoffs for low muscle mass and strength in a population of Turkish elderly adults. Aging Clin Exp Res. 2020 Sep;32(9):1749-1755. doi: 10.1007/s40520-019-01448-4. Epub 2020 Jan 2.