Clinical trial NCT05872451: Current Intensity for the Obturator Nerve Block
Official title: The Difference in the Current Intensity for the Obturator Nerve Block According to the Presence or Absence of Neuromuscular Blockage
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Bladder Tumor
Keywords: Transurethral Resection of Bladder
Obturator Nerve
Nerve Block
Neuromuscular Blockade
Anesthesia, General
Lead sponsor: Chosun University Hospital
Sponsor class: OTHER
First posted: 2023-05-24
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Patients undergoing TURP procedure under general anesthesia
Primary purpose: OTHER

Brief summary: The purpose of the present study was to find out the difference in current intensity required for nerve stimulation according to the presence or absence of neuromuscular blockade during the obturator nerve block procedure for TURP.

Detailed description: During the transurethral resection of bladder tumors (TURBT) procedure under spinal anesthesia, the obturator nerve block is required to prevent the accidental movement of adductor longus muscles by electrical stimulation. However, during general anesthesia, the contraction of the adductor longus muscle would be lost due to deep neuromuscular blockade. However, some reports showed that the contraction of the adductor longus muscle occurs even in the deep neuromuscular blockade.

The current intensity for the nerve stimulation during nerve block is 0.3--0.5 mA when the needle tip is near the nerve. However, it is still unknown what current intensity is required to show the contraction of the adductor longus muscle when the patient is in a deep neuromuscular blockade.

Therefore, in this study, investigators aimed to determine the difference in current intensity required for nerve stimulation according to the presence or absence of neuromuscular blockade during obturator nerve block for TURP. In addition, investigators aimed to determine that the obturator nerve block is required during the TURP procedure in patients with deep neuromuscular blockade during general anesthesia.

Eligibility criteria: Inclusion Criteria:

* Patients undergoing TURP procedure

Exclusion Criteria:

* Patients with anatomical or functional anomaly in the upper airways
* Patients with neuromuscular disease
* Patients with hip joint disorders
* BMI of \< 18.5 or \> 30.0 kg/m2

Primary outcomes:
measure: Initial current intensity
timeFrame: About 5 minutes after starting obturator nerve block procedure
measure: Final current intensity
timeFrame: About 10 minutes after starting obturator nerve block procedure
Secondary outcomes:
measure: Current intensity after the administration of rocuronium (0.6 mg/kg)
timeFrame: Between 5 minutes and 10 minutes after starting obturator nerve block procedure
Other outcomes:
Locations:
city: Gwangju
country: Korea, Republic of
facility: Chosun University Hospital
Study officials:
affiliation: Chosun University Hospital
name: Ki Tae Jung, M.D., Ph.D.
role: STUDY_CHAIR
References:
citation: Koo CH, Ryu JH. Anesthetic considerations for urologic surgeries. Korean J Anesthesiol. 2020 Apr;73(2):92-102. doi: 10.4097/kja.19437. Epub 2019 Dec 17.