Clinical trial NCT05257616: Effect of Cervical Mobility on Cardiovascular And Respiratory Outcomes Among Young Adults
Official title: Effect of Cervical Mobility on Cardiovascular And Respiratory Outcomes Among Young Adults
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Neck Pain
Blood Pressure
Keywords: Neck pain
Blood pressure
Heart rate
Range of motion
Respiratory rate
Lead sponsor: Shifa Tameer-e-Millat University
Sponsor class: OTHER
First posted: 2022-02-25
Enrollment: 84
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: It include the control and experimental group.
Primary purpose: PREVENTION

Brief summary: In some individuals, neck pain subsides within a year but reappearance is surpassing while for some patients it prevails for lifetime. According to a study on global burden of disease performed in 2010, neck pain was rated as number 4th when measured with Years Lived With Disability (YLDs) and stood 21st when overall burden was concerned. The estimated 1 year incidence of neck pain from available studies ranges between 10.4% and 21.3% with a higher incidence noted in office and computer workers. While the overall prevalence of neck pain in the general population ranges between 0.4% and 86.8% ; point prevalence ranges from 0.4% to 41.5% and 1 year prevalence ranges from 4.8% to 79.5%. Occurrence of neck pain is generally higher in women, high-income countries compared with low- and middle-income countries and in urban areas compared with rural areas. In addition, the patient characteristics like psychosocial factors are determinants, risk factors and prognostic factors of neck pain but this knowledge doesn't provide adequate information to the physician to deal with such patients.

Detailed description: Neck pain is the sense of discomfort that could be felt in the cervical and upper thoracic region. It's an ubiquitous human perception. Non-specific neck pain has a postural or mechanical basis and affects about two thirds of people at some stage, especially in the middle age. Acute neck pain resolves within days or weeks, but may become chronic in about 10% of people. Many individuals have asymptomatic neck pain due to various hidden pathologies and improper postural characteristics which is only noticeable after detailed screening and scans.

Heart and lungs are the main organs housed by the thoracic cage with all their vascular and nervous supply passing through the cervical and the thoracic spine. The respiratory system could be affected by the musculoskeletal system of the body. As there are accessory respiratory muscles of respiration that are attached to the neck, chest wall and/or abdomen.

Bad posture, for instance, can lead to reduction in power of the neck muscles hence reducing power of the respiratory muscles creating negative effect on the thoracic expansion, alveolar ventilation, reducing lung volume and vital capacity.

Every health system is indicated by certain measures, vital signs are indicative of the health of cardiovascular and respiratory system as well as body as a whole. These physiological observations generally include blood pressure (BP), heart rate (HR), and ventilation rate (VR), temperature (Temp), and oxygen saturation (SPO2) in the blood. Another vital sign, known as the fifth vital sign is Pain.

Changes or deviation of the vital signs from its normal ranges help evaluate and manage any adverse event such as cardiac arrest or sudden death and help in preventing many such deadly events by early recognition and prompt treatments and also help reduce mortality and morbidity.

Several studies have been known to show that alterations in vital signs are not only seen as a result of any pathological event but also any non-pathological as well. Any type of physiological movements of body part such as the spine as a whole or interventional movements, several exercises, mobilization or manipulations, to any segment of the spine like cervical, thoracic or lumbar, have a specific effect on the vital signs.

Eligibility criteria: Inclusion Criteria:

* Cervical pain
* Cervical hypo mobility

Exclusion Criteria:

* History of cervical trauma or injury
* Any structural deformity
* Vertebral instability
* Cardiac and respiratory complications

Primary outcomes:
measure: Cardiac outcome
timeFrame: 4 weeks
measure: Respiratory outcome
timeFrame: 4 weeks
measure: Vascular Outcome
timeFrame: 4 weeks
measure: Oxygen Saturation
timeFrame: 4 weeks
Secondary outcomes:
measure: Range of motion of cervical spine
timeFrame: 4 weeks
measure: Numeric Pain Rating Scale
timeFrame: 4 weeks
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Shifa tameer e millat university
state: Federal
Study officials:
affiliation: Shifa tameer e millat university Islamabad
name: Zoya Mehmood, MS-OMPT
role: PRINCIPAL_INVESTIGATOR
References:
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