Clinical trial NCT05352789: Nutrition and Metabolic Prehabilitation in HSCT Patients UK and ROI. BSBMT Multi-centre Survey.
Official title: Exploration of Nutrition and Metabolic Prehabilitation Practices for Haematopoietic Stem Cell Transplant (HSCT) in UK and ROI Transplant Centres: A BSBMT Multi-centre Survey
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Haematological Malignancy
Bone Marrow Transplant Complications
Stem Cell Transplant Complications
Nutrition Aspect of Cancer
Nutritional and Metabolic Disease
Exercise Interventions
Prehabilitation
Keywords: nutrition
metabolism
exercise
bone marrow transplant
stem cell transplant
autologous transplant
allogeneic transplant
prehabilitation
Lead sponsor: Nottingham University Hospitals NHS Trust
Sponsor class: OTHER
Collaborators: name: University of Nottingham
name: University of Sheffield
name: Sheffield Teaching Hospitals NHS Foundation Trust
First posted: 2022-04-29
Enrollment: 66
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Health care professionals working within an adult HSCT setting

Brief summary: To explore current practices of nutrition and metabolic screening, assessment and management prior to Haematopoietic Stem Cell Transplant (HSCT) in UK and ROI transplant centres.

Nutrition and metabolic parameters assessed in the survey include glycaemic control, lipid function, liver function, nutritional screening, nutritional assessment, nutrition intervention (tube feeding, diet, micronutrient) and exercise.

This work will be used to inform the design of a UK dual centre feasibility study of personalised nutrition and metabolic care for HSCT patients prior to transplantation.


Eligibility criteria: Inclusion Criteria:

* BSBMT registered adult HSCT centres (including TYA services where patients have opted to be treated in an adult service pathways)
* Centres delivering either autologous or allogeneic stem cell transplants

Exclusion Criteria:

* All paediatric HSCT services

Primary outcomes:
measure: To understand the routine screening, assessment and management practices of nutritional and metabolic parameters prior to haematopoeitic stem cell transplantation in UK centres
timeFrame: Aug 20- March22
measure: Differences in frequency of glycaemic screening prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in frequency of assessments of lipid profile screening prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in frequency of assessments of liver and renal function prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in nutritional screening and assessment practices done prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in body composition assessments given prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in dietary advice given prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in enteral feeding practices prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in specialist dietary advice given prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
measure: Differences in physical assessment, advice and delivery prior to HSCT across UK and ROI HSCT centres and between health professionals
timeFrame: Aug 20-March22
Secondary outcomes:
measure: To understand perceptions on the role and value of prehabilitation in HSCT
timeFrame: Aug 20-March22
measure: Perceptions on best composition of prehabilitation programme prior to HSCT.
timeFrame: Aug 20-March22
measure: Description of current HSCT prehabilitation services in adult services in UK and ROI
timeFrame: Aug 20-March22
Other outcomes:
Locations:
city: Nottingham
country: United Kingdom
facility: Nottingham University Hospitals NHS Trust
state: Nottinghamshire
Study officials:
References: