Clinical trial NCT06016816: The Effect of Bilateral Sphenopalatine Ganglion Block on Postoperative Pain in Patients to be Subject to Septorhinoplasty Surgery
Official title: The Effect of Bilateral Sphenopalatine Ganglion Block on Postoperative Pain in Patients to be Subject to Septorhinoplasty Surgery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anesthesia of Mucous Membrane
Keywords: sphenopalatine ganglion block
septhorhinoplasty
general anesthesia
Lead sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Sponsor class: OTHER
First posted: 2023-08-30
Enrollment: 72
Sex: ALL
Minimum age (years): 17
Maximum age (years): 45
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study is to examine the effects of bilateral sphenopalatine ganglion block on surgical conditions, hemodynamics, intraoperative and postoperative analgesic use, recovery characteristics, and postoperative pain during septorhinoplasty under general anesthesia. The study was planned as double-blind, randomized, controlled. 72 patients who will undergo septorhinoplasty surgery will be collected. (g power analysis was performed.) Evaluation of the effectiveness of bilateral sphenopalatine ganglion block was planned. Patients will be divided into 2 equal groups (36 patients). After the induction of general anesthesia, one group (Group: 1) will be administered 8mg dexamethasone and 10mg bupivacaine submucosal, the other group (group:2) will be administered 4 cc saline. aspects will be evaluated.


Eligibility criteria: Inclusion Criteria:

- patients with an ASA score of I-II and between the ages of 17-45 years, who were to undergo general anesthesia with desflurane, were included in the study.

Exclusion Criteria:

* Patients aged \<17 and \>45 years, patients with liver and/or kidney failure, obese patients (BMI \>30), trauma patients, ASA III-IV patients, patients with bleeding disorders, those using drugs that may affect the coagulation system, patients with cardiomyopathy, cerebrovascular disease, immobility, and malnutrition were excluded from the study.

Primary outcomes:
measure: Numeric Rating Scale
timeFrame: Postoperative 0-2 hours, 2-8 hours,8-24 hours
Secondary outcomes:
measure: Riker Agitation Scale
timeFrame: Immediately after extubation
measure: mean arterial pressure
timeFrame: when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubation
measure: heart rate
timeFrame: when you come to the operating room table after anesthesia induction Intraoperative 30 minutes after extubation
measure: intraoperative remifentanil consumption
timeFrame: intraoperative
measure: edema questionnaire
timeFrame: Postoperative 0-2 hours, 2-8 hours,8-24 hours
measure: hematoma questionnaire
timeFrame: Postoperative 0-2 hours, 2-8 hours,8-24 hours
measure: vomiting questionnaire
timeFrame: Postoperative 0-2 hours, 2-8 hours,8-24 hours
measure: Oral analgesic use
timeFrame: In the first 24 hours after surgery
Other outcomes:
Locations:
city: Diyarbakır
country: Turkey
facility: Health Sciences University Gazi Yaşargil Training and Research Hospital
state: Kayapınar
Study officials:
References: