Clinical trial NCT03341663: The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris
Official title: The Diagnostic Value of Acupoint Sensitization Based on Stable Angina Pectoris
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Stable Angina Pectoris
Acupoint Sensitization
Correlation Analysis
Diagnostic Value
Keywords: Stable Angina Pectoris
Acupoint sensitization
Correlation analysis
Diagnostic value
Lead sponsor: West China Hospital
Sponsor class: OTHER
First posted: 2017-11-14
Enrollment: 183
Sex: ALL
Minimum age (years): 35
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients were recruited from the department of cardiology in the West China Hospital of Sichuan University

Brief summary: Investigators adopt cross-sectional study design to carry out the exemplary research in the aspects of disease diagnosis.This study is designed to confirm the hypothesis "acupoint sensitization is associated with a severity of angina pectoris, which may contribute to the diagnosis of stable angina pectoris". After the eligible participants recruited in group, the coronary artery lesions will be evaluated through coronary angiography and the Canadian Cardiovascular Society(CCS) angina pectoris classification will also be evaluated at the same time. The degree of acupoint sensitization will be tested by the electronic Von Frey instrument by one professional acupuncturist with total 12 acupoints, including Shenmen,Yinxi, Shaohao,Jiquan,Neiguan, Ximen, Quze, Shanzhong, Juque, Jueyinyu, Xinyu, Duyu. Analysis were conducted to explore relationships between the degree of acupoint sensitization, the degree of coronary artery stenosis and CCS angina pectoris classification. Diagnostic value will be further analyzed in the final step.


Eligibility criteria: Inclusion Criteria:

* Patients meet the diagnostic criteria of ACC/AHA angina pectoris of coronary heart disease
* The frequency of angina attacks were greater or equal to twice a week over the previous 3 months
* Patients agree to do coronary angiography examination and sign the informed consent.

Exclusion Criteria:

* People with mental disabilities and intelligent obstacle
* Patients who can't accomplish the detection of acupoint sensitization
* Patients with allergic condition, especially the contrast media
* Patients with acute myocardial infarction, unstable angina, during arrhythmia and serious diseases which can affect the blood supply of myocardial
* Patients with skin or peripheral nerve paresthesia, pain or the detect area of skin ulcerate
* Pregnant or lactating women
* Patients who undergoing other clinical trials

Primary outcomes:
measure: The degree of acupoint sensitization
timeFrame: About 1 hour
measure: The degree of coronary artery stenosis
timeFrame: About 2 hours
measure: Canadian Cardiovascular Society angina pectoris classification
timeFrame: About 1 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Chengdu
country: China
facility: The West China Hospital of Sichuan university
state: Sichuan
Study officials:
References: