Clinical trial NCT06510686: Effects of Core Stabilization and Inspiratory Muscle Training in Patients With COPD
Official title: Comparison of the Effects of Core Stabilization and Inspiratory Muscle Training on Diaphragm Activation, Inspiratory Muscle Strength, Functional Capacity, Respiratory Functions, Physical Activity and Quality of Life in Patients With COPD
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Copd
Lead sponsor: Gulhane School of Medicine
Sponsor class: OTHER
First posted: 2024-07-19
Enrollment: 38
Sex: ALL
Minimum age (years): 18
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the respiratory workload. This results in impaired coordination of muscle groups, leading to muscle dysfunction. Respiratory muscle dysfunction is a significant determinant of life expectancy in COPD. Additionally, respiratory muscles unable to cope with increased workloads lead to impaired respiratory functions and reduced exercise capacity.

It is widely accepted that appropriate training of respiratory muscles can increase their strength, endurance, and their close relationship with lung volume capacities. Besides their role in respiration, respiratory muscles also contribute to postural function and core stabilization. Studies on respiratory muscle training in COPD have primarily focused on inspiratory muscle strength training, neglecting the core stabilization function of respiratory muscles. However, optimal gains in a muscle can only be achieved with training tailored to its functional characteristics. Therefore, a comprehensive training program should be developed considering the multifunctional nature of respiratory muscles. Studies published in healthy individuals and different patient populations demonstrate that core training can improve lung functions. The aim of this study is to compare the effects of inspiratory muscle training and core stabilization training on diaphragm activation, inspiratory muscle strength, functional capacity, respiratory functions, physical activity, and quality of life in individuals with COPD.


Eligibility criteria: Inclusion Criteria:

* Being over 18 years old
* Having a diagnosis of COPD according to the GOLD criteria and being at stage 3 or lower
* Not being in an acute exacerbation period and having at least one month since the last exacerbation
* Being able to walk independently
* Having sufficient mental capacity to understand the tasks in the study (Mini-Mental Test \>24)
* Being willing to participate in the study

Exclusion Criteria:

* Being a stage 4 COPD patient according to the GOLD criteria
* Having a diagnosis of lung cancer, pulmonary hypertension, and heart failure
* Being in a COPD exacerbation period
* Scoring below 24 on the Mini-Mental Test
* Having any other disease that affects respiratory functions
* Having undergone pulmonary surgery

Primary outcomes:
measure: Inspiratory Muscle Strength
timeFrame: 8 weeks
measure: Inspiratory Muscle Activation
timeFrame: 8 weeks
measure: Respiratory function tests FEV1
timeFrame: 8 weeks
measure: Respiratory function tests FVC
timeFrame: 8 weeks
measure: Respiratory function tests PEF
timeFrame: 8 weeks
measure: Respiratory function tests FEV1/FVC
timeFrame: 8 weeks
measure: Respiratory function MVV
timeFrame: 8 weeks
measure: Functional capacity
timeFrame: 8 weeks
measure: Symptoms
timeFrame: 8 weeks
Secondary outcomes:
measure: Physical activity,
timeFrame: 8 week
measure: Quality of life Tests
timeFrame: 8 week
measure: Core Strength
timeFrame: 8 week
measure: Core Strength flexion
timeFrame: 8 week
measure: Core Strength extension
timeFrame: 8 week
measure: Core Strength side bridge
timeFrame: 8 week
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Sağlık Bilimleri Üniversitesi
Study officials:
References: