Clinical trial NCT03085498: Sportcheck Follow-Up
Official title: Sportcheck Follow-Up: Physical Fitness, Cardiovascular and Psychosocial Health in Primary School Childen
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cardiovascular Diseases
Childhood Obesity
Hypertension
Keywords: retinal vessels
physical activity
children
psychosocial health
Lead sponsor: University of Basel
Sponsor class: OTHER
First posted: 2017-03-21
Enrollment: 280
Sex: ALL
Minimum age (years): 10
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This study will be designed as a four-year follow-up of the 2014 Sportcheck. All first-graders of primary schools in the canton Basel-Stadt took part in measurements of height, body weight and physical fitness during physical education lesson. From the 1255 children, 540 (43%) were allowed by their parents to join additional measurements of blood pressure and retinal vessel diameters and filled in questionnaires. In the year 2018, all fifth-graders of Basel-Stadt will be invited to take part in the same measurements as in 2014. All children will again conduct physical fitness tests and measurements of height and body weight during physical education. All children with an informed consent will participate in the same medical tests that were performed four years previously.

Brief summary: The study resembles a four-year follow-up on the influence of physical activity and fitness, blood pressure, BMI and stress on vascular health in primary schoolchildren. It examines the predictive value of retinal vessel diameters for the development of childhood hypertension.

Detailed description: The study aims to examine the usefulness of retinal vessel analysis in childhood cardiovascular prevention. It investigates the long-term influence of physical activity and fitness on retinal vessel diameters, blood pressure, BMI and psychosocial stress in children. The study aims to set new standards for an integrative primary prevention concept to initiate healthy ageing from childhood to adulthood.

Eligibility criteria: Inclusion Criteria:

* All fifth-graders of public primary schools in Basel-Stadt with an informed consent signed by their parents are included.

Exclusion Criteria:

* Fifth-graders with motor-or other disabilities that do not allow participation will be excluded.

Primary outcomes:
measure: Retinal vessel diameter
timeFrame: Through study completion, an average of 1 year
Secondary outcomes:
measure: Blood pressure
timeFrame: Through study completion, an average of 1 year
measure: Body mass index (BMI)
timeFrame: Through study completion, an average of 1 year
measure: Psychosocial stress exposure as assessed by the conflict subscale of the Family Environment Scale
timeFrame: Through study completion, an average of 1 year
measure: Health behavior as assessed by the HBSC Symptom Checklist
timeFrame: Through study completion, an average of 1 year
measure: Health-related quality of life as assessed by the KINDL-R questionnaire
timeFrame: Through study completion, an average of 1 year
Other outcomes:
Locations:
city: Basel
country: Switzerland
facility: Bereich Sport- und Bewegungsmedizin, Abteilung Präventive Sportmedizin & Systemphysiologie
state: Basel Stadt
Study officials:
affiliation: University of Basel
name: Henner Hanssen, Prof. Dr.
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Basel
name: Lukas Zahner, Prof. Dr.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Lona G, Hauser C, Bade S, Kochli S, Infanger D, Endes K, Faude O, Hanssen H. Association of Parental Socioeconomic Status and Physical Activity with Development of Arterial Stiffness in Prepubertal Children. Int J Environ Res Public Health. 2021 Aug 3;18(15):8227. doi: 10.3390/ijerph18158227.
citation: Lona G, Hauser C, Kochli S, Infanger D, Endes K, Faude O, Hanssen H. Blood Pressure Increase and Microvascular Dysfunction Accelerate Arterial Stiffening in Children: Modulation by Physical Activity. Front Physiol. 2020 Dec 17;11:613003. doi: 10.3389/fphys.2020.613003. eCollection 2020.