Clinical trial NCT02846363: REACT AGAINST STROKE
Official title: REACT AGAINST STROKE
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Stroke
Keywords: stroke
public awareness campaign
call to EMS
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2016-07-27
Enrollment: 2649
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Acute stroke suspicion patients calling the EMS of the Rhone and Isere area at the 3 periods of evaluation.

Brief summary: Acute stroke management represents a true medical emergency that requires prompt diagnosis and urgent treatment. In a previous exhaustive cohort study conducted in the Rhône region, France (AVC69) the investigators observed that only a small percentage of patients could access to thrombolysis in time. In this cohort of 1306 patients treated in one of the emergency department of the Rhone region for a suspected stroke, 84% of patients reached hospital through an emergency department instead of going directly to a stroke unit. Among those patients, only 8% were finally thrombolysed, because of extended management times.. Our hypothesis was that public awareness campaign designed to improve public's knowledge and skills would consequently reduce prehospital time and favour call to prehospital emergency medical services (EMS).

The investigators will conduct an awareness campaign aimed at the general population, using different communication media, the content will be developed based on the results of a qualitative study with focus groups (Quali-AVC), and using a diffusion plan established with communications professionals. To assess the effects of this campaign, a comparative quasi-experimental before-after study will be conducted. A control region where no awareness stroke program has been set up has been selected, data will be collected in the two regions. The assessment of the impact of the campaign will focus on the comparison of the evolution of indicators between these two regions. Three assessment time will be provided: before starting the program, at 3 months and at the end of the program.


Eligibility criteria: Inclusion Criteria:

- All adult patients calling EMS for suspected stroke identified by at least one symptom among face paralysis, limb paralysis or speech disorder (FAST positive)

Exclusion Criteria:

- age below 18

Primary outcomes:
measure: Increase the number of calls to EMS (French call number 15) for stroke
timeFrame: 24 hours
Secondary outcomes:
measure: reduction of the time between symptoms and call to EMS for suspected stroke
timeFrame: 24 hours
measure: increase in the number of calls to EMS for stroke within 3 hours after symptoms onset
timeFrame: 3 hours
measure: Knowledge of the general population about stroke
timeFrame: 12 months
measure: recognition of the need to immediately call EMS when faced with stroke suspicion
timeFrame: 12 months
Other outcomes:
Locations:
city: Lyon
country: France
facility: Pôle Information Médicale, Evaluation, Recherche 162 avenue Lacassagne
Study officials:
affiliation: Hospices Civils de Lyon
name: Anne-Marie SCHOTT, Pr
role: PRINCIPAL_INVESTIGATOR
References:
citation: Haesebaert J, Laude C, Termoz A, Bravant E, Perreton N, Bony T, Trehard H, Porthault S, Derex L, Nighoghossian N, Schott AM. Impact of a theory-informed and user-centered stroke information campaign on the public's behaviors, attitudes, and knowledge when facing acute stroke: a controlled before-and-after study. BMC Public Health. 2020 Nov 16;20(1):1712. doi: 10.1186/s12889-020-09795-y.