Clinical trial NCT05127187: Estimation of the Prevalence of HIV, Hepatitis C and Hepatitis B Infection Among Detainees in the Nîmes Administrative Detention Center
Official title: Estimation of the Prevalence of HIV, Hepatitis C and Hepatitis B Infection Among Detainees in the Nîmes Administrative Detention Center
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: HIV Infections
Hepatitis C
Hepatitis B
Lead sponsor: Centre Hospitalier Universitaire de Nīmes
Sponsor class: OTHER
First posted: 2021-11-19
Enrollment: 350
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All detainees arriving at the Administrative Detention Center of Nîmes from Monday to Friday, and those arriving over the weekend if still present by Monday.

Brief summary: People in Administrative Detention Centers often come from areas of medium or high HIV, hepatitis C \& B endemic, and are often unaware of their serological status. Currently, HIV, hepatitis C \& B screening is not systematically performed at the CRA of Nîmes, and when performed, serological tests are used. The main disadvantage of this method is the length of time it takes to obtain the results, with subjects frequently discharged before receiving their results.

To improve the care of these vulnerable persons, the aim of this study is to estimate the prevalence of HIV, hepatitis C and hepatitis B in the detainees of the administrative detention center of Nîmes, by systematically screening with a rapid diagnosis test. In case of a positive rapid diagnosis test test, a serology test will confirm the rapid diagnosis test result.


Eligibility criteria: Inclusion Criteria:

* The patient must have given their free and informed oral consent
* Patient detained in the Nîmes Administrative Detention Center

Exclusion Criterion

• It is impossible to give the subject informed information

Primary outcomes:
measure: Prevalence of HIV infection in detainees at the Nîmes Administrative Detention Center
timeFrame: Inclusion
measure: Prevalence of Hepatitis C infection in detainees at the Nîmes Administrative Detention Center
timeFrame: Inclusion
measure: Prevalence of Hepatitis B infection in detainees at the Nîmes Administrative Detention Center
timeFrame: Inclusion
Secondary outcomes:
measure: Prevalence of co-infections between HIV, Hepatitis C and Hepatitis B
timeFrame: Inclusion
measure: Participant country of origin
timeFrame: Inclusion
measure: Knowledge of HIV, Hep C and Hep B status
timeFrame: Inclusion
measure: Participant previous transfusion
timeFrame: Inclusion
measure: Intravenous drug use
timeFrame: Inclusion
measure: Intranasal drug use
timeFrame: Inclusion
measure: Shared drug paraphernalia
timeFrame: Inclusion
measure: Non-protected sexual activity
timeFrame: Inclusion
measure: Participant with piercings
timeFrame: Inclusion
measure: Participant with tattoos
timeFrame: Inclusion
measure: Feasibility of screening
timeFrame: End of study (1 year)
measure: Acceptability of the screening
timeFrame: End of study (1 year)
Other outcomes:
Locations:
city: Nîmes
country: France
facility: CHU Nîmes
Study officials:
affiliation: Centre Hospitalier Universitaire de Nīmes
name: Mélanie Kinne
role: PRINCIPAL_INVESTIGATOR
References: