Clinical trial NCT03075163: Post-Operative Therapy for Nausea or Vomiting
Official title: Optimization of Post-Operative Therapy for Nausea or Vomiting
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: PHASE4
Conditions: Vomiting
Nausea
Keywords: PONV
Nausea
Vomiting
Acupressure
Lead sponsor: University of California, Davis
Sponsor class: OTHER
First posted: 2017-03-09
Enrollment: 300
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This is a single site, prospective, randomized controlled study designed to evaluate the impact of acupressure when used as an initial treatment before rescue medications in the treatment of post-operative nausea and/or vomiting at UCD.

Detailed description: Each individual will only participate in the post anesthetic care unit starting from when the patient's nurse or anesthesiology team deems that the patient needs treatment for PONV. It ends when the patient is discharged from anesthesiology care.

Patients will be asked to score nausea before randomized treatment of acupressure or medication, and to score nausea after treatment.

Eligibility criteria: Inclusion Criteria:

- Patients scheduled for elective surgery requiring general anesthesia

Exclusion Criteria:

* Age less than 18 years
* Adults unable to give primary consent
* Pregnancy
* Prisoners
* Unable to access pericardial 6 acupressure point bilaterally post procedure
* Allergy to Ondansetron

Primary outcomes:
measure: Change in Nausea Score
timeFrame: Time to discharge from post anesthetic care unit
Secondary outcomes:
Other outcomes:
Locations:
city: Sacramento
country: United States
facility: UC Davis Health
state: California
Study officials:
affiliation: University of CA, Davis
name: Paul Marc, MD, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: University of CA, Davis
name: Neal W Fleming, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
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