Clinical trial NCT06209944: Charlson Comorbidity Index and Outcome of Cardiopulmonary Resuscitation in Geriatric Patients in Hong Kong
Official title: A Retrospective Review on Charlson Comorbidity Index (CCI) as a Predictor of Return-of-spontaneous-circulation and Survival-to-discharge of Geriatric In-hospital Cardiopulmonary Resuscitation (CPR) in a Regional Acute Hospital in Hong Kong
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Comorbidities and Coexisting Conditions
Cardiopulmonary Resuscitation
Geriatrics
Lead sponsor: Haven of Hope Hospital
Sponsor class: OTHER
First posted: 2024-01-18
Enrollment: 394
Sex: ALL
Minimum age (years): 65
Maximum age (years): 101
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (a regional acute hospital with total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018

Brief summary: The goal of this observational study is to learn about the factors affecting the outcome (survival) of cardiopulmonary resuscitation in older persons in a hospital. The main questions it aims to answer are:

* Whether age would affect outcome
* Whether Charlson Comorbidity Index would affect outcome
* Whether the conditions (e.g. heart rhythm) immediately before resuscitation would affect survival.

Researchers would compare the patients who deceased with the patients who survived.

Detailed description: The goal of this review was to investigate the impact of age, existing medical conditions. and other factors before cardiac arrest in predicting outcome of in-hospital cardiopulmonary resuscitation (CPR) of older persons.

It was conducted on all patients aged ≥ 65, who underwent CPR in acute medical and geriatric wards (excluding Intensive Care Unit) in United Christian Hospital from January 2017 to December 2018.

Eligibility criteria: Inclusion Criteria:

* All adults aged 65 or above with in-hospital cardiac arrest and undergoing CPR in wards of Department of Medicine and Geriatrics (excluding Intensive Care Unit (ICU)) in United Christian Hospital (total bed 1,174 with 16 ICU beds) in Hong Kong from 1 January 2017 to 31 December 2018
* In patients with multiple resuscitation events, only the first in-hospital CPR was included.

Exclusion Criteria:

* Patients with existing Do-Not-Attempt-Cardiopulmonary-Resuscitation (DNACPR) order
* Patients younger than 65 years old
* Out-of-hospital CPR in the index admission
* CPR occurred in ICU / Emergency Department / Operating Theatre / wards other than medical wards

Primary outcomes:
measure: sustained return of spontaneous circulation (ROSC), survival at 24 hours, survival at hospital discharge, and at 1 year.
timeFrame: 2017 - 2018
Secondary outcomes:
Other outcomes:
Locations:
city: Hong Kong
country: China
facility: Haven of Hope Hospital
state: Hong Kong
Study officials:
affiliation: Haven of Hope Hospital, Hong Kong
name: JANE YIDAN ZHU
role: PRINCIPAL_INVESTIGATOR
References: