Clinical trial NCT00153504: Housing and Health Study
Official title: Housing and Health Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: HIV
AIDS
Keywords: HIV
AIDS
Homeless
Homelessness
Housing
HIV seropositive
HIV risk behavior
Lead sponsor: Centers for Disease Control and Prevention
Sponsor class: FED
Collaborators: name: US Department of Housing and Urban Development
name: RTI International
name: Johns Hopkins University
name: University of Pittsburgh
name: Columbia University
First posted: 2005-09-12
Enrollment: 630
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The goal of the project is to examine the impact of providing housing for people living with HIV who are homeless or at imminent risk of homelessness on their HIV disease progression, risks of transmitting HIV, and medical care access and utilization.

Detailed description: Evidence is accumulating that homelessness and housing may be important factors that influence human immunodeficiency virus (HIV) sex and drug risk behaviors. Despite this apparent connection, few studies have investigated whether homelessness or unstable housing, compared with stable and adequate housing, is linked with HIV risk behaviors, and whether change in housing status is associated with change in risk behaviors.

The Housing and Health Study is a multi-site, multi-agency research collaboration. This project is a unique collaboration between federal agencies (the Department of Housing and Urban Development and the Centers for Disease Control and Prevention), local government agencies, universities, and private not-for-profit organizations.

The goal of the project is to examine the impact of providing housing for people living with HIV who are homeless or at imminent risk of homelessness on their disease progression, their risks of transmitting HIV, and medical care access and utilization. A total of 630 people living with HIV from three study sites complete the baseline study sessions. Half the participants (n=315) are randomly assigned to each of the two study groups. Treatment group participants receive Housing and Health Study housing rental assistance, and comparison group participants receive assistance finding housing according to local standard practice.

At baseline, 6, 12, and 18 months after baseline, participants complete study questionnaires and provide blood specimens to test for CD4 and viral load. In addition, the cost effectiveness of the study will be investigated by examining the HIV-related costs averted by providing housing to persons at high risk for transmitting HIV.

Eligibility criteria: Inclusion Criteria:

* HIV seropositive
* At least 18 years of age
* English or Spanish speaking
* Able to provide informed consent
* Able to participate in data collection protocol
* Categorized as low income (less than 80% of the Area Median Income)
* Homeless or at imminent risk of homelessness
* Able to provide information about identity

Exclusion Criteria:

-

Primary outcomes:
measure: HIV risk behaviors at 6, 12, and 18 months
measure: Biological measures of HIV-related health status
measure: Access to HIV/AIDS medical care
measure: Adherence to HIV/AIDS medical care, including compliance with HIV medication therapies
Secondary outcomes:
measure: Cost and cost effectiveness of the intervention
measure: Proximal outcomes (e.g., increased condom use self-efficacy, social norms) associated with a reduction in HIV risk behaviors
measure: Social contact, employment outcomes, quality of life, mental health
Other outcomes:
Locations:
Study officials:
affiliation: Centers for Disease Control and Prevention
name: Daniel P Kidder, PhD
role: PRINCIPAL_INVESTIGATOR
References: