Clinical trial NCT01014663: Non-contact Boxing Training and Traditional Therapeutic Exercise for Persons With Parkinson's Disease
Official title: Comparison of Non-contact Boxing Training and Traditional Therapeutic Exercise on Functional Outcomes in Persons With Parkinson's Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson's Disease
Keywords: Parkinson's disease
exercise
training program
rehabilitation
boxing
Lead sponsor: University of Indianapolis
Sponsor class: OTHER
First posted: 2009-11-17
Enrollment: 31
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The primary purpose of this study is to compare the effects of a non-traditional boxing training program to a traditional therapeutic exercise program on activity and participation outcomes in persons with Parkinson's disease. Thirty participants will be randomly assigned to participate in either non-contact boxing training or traditional therapeutic exercise for 36 sessions over 12 weeks. Participants will be measured immediately before (pre-test) and after (post-test) the intervention.

Detailed description: Physical therapists commonly treat patients with Parkinson's disease. Typical clinical interventions used by physical therapists including strengthening, stretching and aerobic training have been shown to improve function and quality of life of persons with Parkinson's disease. Alternative exercise interventions that incorporate non-traditional concepts, such as tango dance, tai chi and taiji have also been found to lead to improvements in function in persons with Parkinson's disease. It is important that comparisons between different types of exercise programs for persons with Parkinson's disease be explored in order to determine effective options for care.

Here in Indianapolis, Indiana, individuals with Parkinson's disease have a unique opportunity for alternative exercise with the recent development of the popular non-contact boxing training program offered by the Rock Steady Boxing Foundation. Therefore, the purpose of this study is to compare the effects of the non-traditional boxing training program to a traditional therapeutic exercise program on activity and participation outcomes in persons with Parkinson's disease.

Thirty participants with Parkinson's disease will be recruited from Central Indiana. All potential participants will be screened to determine eligibility for the study. Participants who are eligible and give consent will be randomly assigned to participate in either the non-contact boxing training or the traditional therapeutic exercise program for 36 sessions lasting over 12 weeks with 60-90 minutes of exercise each session. Participants will be measured immediately before (pre-test) and after (post-test) the intervention period.

Eligibility criteria: Inclusion Criteria:

* diagnosis of Parkinson's disease
* currently not receiving physical therapy services
* medically stable with a physician release stating approval to enter an exercise program
* independently ambulatory in the home setting with or without the use of an assistive device
* able to follow at least three step verbal commands
* available for the entire period of the study
* have transportation to and from training and measurement sessions

Exclusion Criteria:

* preexisting neurological conditions other than Parkinson's disease
* current musculoskeletal conditions that would limit participation in either training program
* significant orthopedic surgery within the past six months
* past brain surgery or brain stimulator implant
* currently known pregnant
* pre-existing cardiovascular conditioner that would prohibit participation in an exercise program

Primary outcomes:
measure: Mobility: Measured with the Timed Up and Go Test; Four-Square Step Test; Six-Minute Walk Test; Berg Balance Scale; Functional Reach Test
timeFrame: Each outcome measures is assessed at pre-test (immediately before intervention), post-test (immediately after the 12 week intervention).
Secondary outcomes:
measure: Participation: measured with the Activities Specific Balance Confidence Scale and the Parkinson's disease Quality of Life Scale
timeFrame: Each outcome measures is assessed at pre-test (immediately before intervention), post-test (immediately after the 12 week intervention).
Other outcomes:
Locations:
city: Indianapolis
country: United States
facility: University of Indianapolis, Krannert School of Physical Therapy
state: Indiana
Study officials:
affiliation: University of Indianapolis
name: Stephanie A Combs, PT, PhD, NCS
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Indianapolis
name: Dyer M Diehl, PT, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Indianapolis
name: William H Staples, PT, DPT, GCS
role: PRINCIPAL_INVESTIGATOR
References: