Clinical trial NCT03275935: Evaluation of Inhalation Technique in Patients With COPD, Asthma or ACOS Using a Dry Powder Device (DPI)
Official title: Evaluation of Inhalation Technique in Patients With Chronic Obstructive Pulmonary Disease (COPD), Asthma or Asthma-COPD Overlap Syndrome(ACOS) Using a Dry Powder Device at Chest Clinic in Dhulikhel Hospital
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: COPD Asthma
Asthma-COPD Overlap Syndrome
Inhalation
Keywords: ACOS
Asthma
COPD
inhalation technique
Lead sponsor: Kathmandu University School of Medical Sciences
Sponsor class: OTHER
First posted: 2017-09-08
Enrollment: 307
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients presenting to Chest Clinic of Dhulikhel hospital, who were diagnosed of having either COPD, Asthma or Asthma-COPD Overlap Syndrome and are currently under inhalational bronchodilators in the form of Dry Powder Device (DPIs)

Brief summary: This study analyzes the prevalence of patients using inhalation devices via incorrect technique and access the adherence of patients to correct inhalation technique when taught along with their subjective improvement of symptoms.

Detailed description: This is a one group pretest- posttest design conducted in all patients presenting in Chest clinic of Dhulikhel Hospital-Kathmandu University Hospital, Nepal from March 2017 to May 2017. Patients diagnosed of having COPD, Asthma or Asthma-COPD Overlap Syndrome (ACOS) and were under inhalation bronchodilators in the form of Dry Powder Device via Rotahaler were included. Enrolled patients are assessed for inhalation technique compliance at their routine medical (pre-training) visits by physician. The use of inhaler device is evaluated in a practical manner by asking the patients to demonstrate their inhalation technique. After the assessment, instructions and training are given until they can use the device correctly. One month later (post-training), all patients are re-evaluated in regards to inhalation technique and subjective improvement of symptoms.

Eligibility criteria: Inclusion Criteria:

* Age \>18 years,
* Diagnosed of having of asthma or COPD or ACOS
* Using dry powder inhaler therapy with Rotahaler

Exclusion Criteria:

* Use of inhaler devices other than Rotahaler
* Newly started on dry powdered inhalational therapy or patients who had recently received face-to-face training program on inhalation technique within the past one month
* Patients in acute exacerbation
* Patients failing to give consent

Primary outcomes:
measure: Change in 'Inhalation Scores" After a month from Baseline
timeFrame: After a month
Secondary outcomes:
measure: Prevalance COPD, Asthma and Asthma COPD Overlap Syndrome inpatients visiting Chest Clinic of Dhulikhel Hospital- Kathmandu University Hospital.
timeFrame: 3 months
measure: Associated Factors for Incorrect Inhalation Technique
timeFrame: 3 months
measure: Prevalence of patients using the inhalation devices via incorrect technique
timeFrame: At pretraining
Other outcomes:
Locations:
city: Dhulikhel
country: Nepal
facility: Dhulikhel Hospital- Kathmandu University Hospital
Study officials:
affiliation: Dhulikhel Hospital- Kathmandu University Hospital
name: Dr Sudeep Shrestha, MD, MRCP(UK)
role: PRINCIPAL_INVESTIGATOR
References: