Clinical trial NCT02108340: Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis
Official title: Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Appendicitis
Keywords: Appendicitis
Diagnosis
Microwave radiometry
Ultrasonography
Lead sponsor: Hippocration General Hospital
Sponsor class: OTHER
First posted: 2014-04-09
Enrollment: 40
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: This study will evaluate the use of microwave radiometry in a population of patients diagnosed with acute appendicitis and treated with appendectomy. The main purpose of the study is to report the results of microwave radiometry as a diagnostic tool in acute appendicitis and compare those results with the commonly used ultrasonography.

Detailed description: Patients diagnosed with acute appendicitis from the emergency department of Hippocration General Hospital and treated with appendectomy will be evaluated with microwave radiometry for changes in the temperature of the appendix before its removal.

Subsequently, the results of microwave radiometry for the patients confirmed by the histopathology report to have acute inflammation of the appendix, will be compared with those of the ultrasonography used for the diagnosis of acute appendicitis.

Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of appendicitis
* Surgical removal of appendix
* Pathological confirmation of appendicitis

Exclusion Criteria:

-

Primary outcomes:
measure: Appendix Temperature
timeFrame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Athens
country: Greece
facility: Hippocration General hospital
state: Attiki
Study officials:
affiliation: Hippocration General Hospital
name: Konstantinos G. Toutouzas, MD, PhD
role: STUDY_CHAIR
affiliation: Hippocration General Hospital
name: Evagelia Stamouli, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Toutouzas K, Grassos C, Drakopoulou M, Synetos A, Tsiamis E, Aggeli C, Stathogiannis K, Klettas D, Kavantzas N, Agrogiannis G, Patsouris E, Klonaris C, Liasis N, Tousoulis D, Siores E, Stefanadis C. First in vivo application of microwave radiometry in human carotids: a new noninvasive method for detection of local inflammatory activation. J Am Coll Cardiol. 2012 May 1;59(18):1645-53. doi: 10.1016/j.jacc.2012.01.033.
citation: Arunachalam K, Maccarini PF, De Luca V, Bardati F, Snow BW, Stauffer PR. Modeling the detectability of vesicoureteral reflux using microwave radiometry. Phys Med Biol. 2010 Sep 21;55(18):5417-35. doi: 10.1088/0031-9155/55/18/010. Epub 2010 Aug 25.
citation: Toutouzas K, Grassos H, Synetos A, Drakopoulou M, Tsiamis E, Moldovan C, Agrogiannis G, Patsouris E, Siores E, Stefanadis C. A new non-invasive method for detection of local inflammation in atherosclerotic plaques: experimental application of microwave radiometry. Atherosclerosis. 2011 Mar;215(1):82-9. doi: 10.1016/j.atherosclerosis.2010.12.019. Epub 2010 Dec 23. No abstract available.
citation: Hassan AM, El-Shenawee M. Review of electromagnetic techniques for breast cancer detection. IEEE Rev Biomed Eng. 2011;4:103-18. doi: 10.1109/RBME.2011.2169780.