Clinical trial NCT06669598: ENHANCING PHYSICAL and COGNITIVE EFFICIENCY in INDIVIDUALS AT RISK of DEMENTIA USING WHOLE-BODY ELECTROMYOSTIMULATION
Official title: ENHANCING PHYSICAL and COGNITIVE EFFICIENCY in ELDERLY INDIVIDUALS AT RISK of DEMENTIA USING WHOLE-BODY ELECTROMYOSTIMULATION
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Mild Cognitive Impairment
Keywords: WB-Electromyostimulation; EMS; electrical muscle stimulation; muscle strength; neurodegenerative disease; cardiovascular training
Lead sponsor: University of Molise
Sponsor class: OTHER
First posted: 2024-11-01
Enrollment: 61
Sex: ALL
Minimum age (years): 55
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This study aimed to evaluate the effectiveness of twelve weeks whole-body electrical muscle stimulation combined with aerobic exercises.

Detailed description: This study aimed to evaluate the effectiveness of twelve weeks of WB-EMS (whole-body electrical muscle stimulation at 35Hz and 350 μs) combined with aerobic exercises on a treadmill and rowing machine, in improving physical and cognitive performance in older adults, both healthy and at risk of dementia. The results were compared with those obtained from the same training without WB-EMS.

Eligibility criteria: Inclusion Criteria:

* age from 55 to 85 years;
* no simultaneous participation in any type of supervised physical activity;
* Sedentary lifestyle

Exclusion Criteria:

* mini-mental state examination (MMSE) score of less than 24;
* inability to walk for 6 min without assistance;
* the presence of a medical condition influencing the cognitive and/or motor functions;
* the presence of any counter indication for the utilisation of EMS, such as cardiovascular diseases, stents, cardiac pacemakers, and diabetes mellitus, verified by medical certification.

Primary outcomes:
measure: 30-second arm curl test
timeFrame: At the end of 12 weeks
measure: 30-second sit-to-stand test
timeFrame: At the end of 12 weeks
measure: hand grip strength test
timeFrame: At the end of 12 weeks
measure: 6-minute walking test
timeFrame: At the end of 12 weeks
measure: 8-foot up and go test
timeFrame: At the end of 12 weeks
measure: Chair Sit and Reach Test
timeFrame: At the end of 12 weeks
measure: Soda Pop Test
timeFrame: At the end of 12 weeks
measure: Tinetti Balance and Gait Test
timeFrame: At the end of 12 weeks
measure: Mini-Mental State Examination (MMSE)
timeFrame: At the end of 12 weeks
measure: Rey's Auditory Verbal Learning Test (RAVLT)
timeFrame: At the end of 12 weeks
measure: Stroop Colour and Word Interference Test (SCWT)
timeFrame: At the end of 12 weeks
measure: Trail Making Test (TMT)
timeFrame: At the end of 12 weeks
measure: Attentional Matrices Test
timeFrame: At the end of 12 weeks
measure: Prose recall test ( babcock)
timeFrame: At the end of 12 weeks
measure: Frontal Assessment battery (FAB)
timeFrame: At the end of 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Campobasso
country: Italy
facility: Università degli Studi del Molise
state: CB
Study officials:
References: