Clinical trial NCT06179251: KNOW HOW TO POSITION THE SACCULE AND UTRICULE IN SCANNING
Official title: KNOW HOW TO POSITION THE SACCULE AND UTRICULE IN SCANNING: INTEREST IN INTRAVESTIBULAR DISLOCATIONS OF PISTONS OR CALIPER
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Otosclerosis
Keywords: Otosclerosis
Vestibular dysfunction
Membranous Labyrinth
Lead sponsor: University Hospital, Strasbourg, France
Sponsor class: OTHER
First posted: 2023-12-21
Enrollment: 40
Sex: ALL
Minimum age (years): 6
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adults (≥18 years old) and minors (≥ 6 years old) having received an MRI of the internal ear canals from the HUS between 01/01/2018 and 01/01/2021 or a CT scan of the rocks between 07/01/2015 and 01/01/2021

Brief summary: Titanium pistons cause MRI artifacts that prevent interpretation of the vestibule. This disadvantage is not present on CT but the vestibule is not visible. Hence the interest in creating a model with 6 reference cuts in order to position the utricle and the saccule in the vestibule in CT. Furthermore, the scanner has fewer contraindications, greater availability and a shorter examination time than MRI.

Detailed description: The aim of the study is to analyze six normal sections chosen as reference in histology, high resolution T2 MRI and CT in order to compare them with precise topographical landmarks to position the posterior membranous labyrinth in CT. Then, apply the investigators' observations to cases of operated otosclerosis.

Eligibility criteria: Inclusion Criteria:

* Adults (≥18 years old) and minors (≥ 6 years old)
* Subject having received an MRI of the internal ear canals from the HUS between 01/01/2018 and 01/01/2021 or a CT scan of the rocks between 07/01/2015 and 01/01/2021
* Normal MRI or CT on the side opposite the pathology.
* Normal tonal audiogram on the side opposite the pathology (peripheral facial paralysis assumed to be cold for MRI and petrous fracture for CT).
* Subject who has not expressed his opposition, after information, to the reuse of his data for the purposes of this research.
* Holders of authority who have not expressed their opposition, after information, to the reuse of their child's data for the purposes of this research

Exclusion Criteria:

* Subject having expressed opposition to participating in the study
* Holders of parental authority who have expressed their opposition to the reuse of their child's data for the purposes of this research
* Imaging with artifacts
* Absence of pure-tone audiogram or its abnormality on the side of the ear studied
* Any malformation or pathology of the vestibule on imaging on the side of the ear studied
* Subjects under guardianship or curatorship

Primary outcomes:
measure: Presence or absence of the anatomical structure referenced in the investigators' reading grid on each of the 6 predefined MRI or CT sections
timeFrame: up to 10 month
Secondary outcomes:
Other outcomes:
Locations:
city: Strasbourg
country: France
facility: Service de Radiologie - CHU de Strasbourg - France
Study officials:
References: