Clinical trial NCT06703424: Effects of Light Intensity Physical Activities on Pre-frontal Cortical Activation, Cognitive Function, Sleepiness and Back Pain
Official title: Investigating the Acute Effects of Light Intensity Physical Activities on Pre-frontal Cortical Activation, Cognitive Function, Sleepiness and Back Pain Among Physically Inactive University Students
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Pre-frontal Cortical Oxygenated and Deoxygenated Hemoglobin Levels
Keywords: light-intensity exercise
pre-frontal cortical activation
executive functioning
university students
inactive
Lead sponsor: Nanyang Technological University
Sponsor class: OTHER
Collaborators: name: Sendai University
First posted: 2024-11-25
Enrollment: 23
Sex: ALL
Minimum age (years): 21
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Two-arm intervention, crossover study design
Primary purpose: OTHER

Brief summary: The objective of this randomised controlled trial is to examine the acute effects of two novel light intensity exercise (sit-cycling and stand-twisting) on prefrontal cortical blood oxygenation, executive functioning, sleepiness and back pain among inactive university students.

The main questions it aims to answer are:

* What are the changes in oxygenated haemoglobin (O2Hb) and deoxygenated hemoglobin (HHb) levels in the prefrontal cortex from baseline to immediately after and 20 minutes after a 5-min bout of S-C and S-T compared to sitting for the same duration?
* What are the changes in executive functioning, specifically, n-back test and Word Colour Stroop test performance from baseline to immediately after and 20 minutes after a bout of S-C and S-T compared to sitting for the same duration?
* How does participants' self-rated daytime sleepiness and back pain after a bout of S-C and S-T compare to sitting for the same duration?

Participants will:

* Perform sit-cycling or stand-twisting for 5 mins (experimental condition) and sit for 5 mins (control condition)
* Wear the functional near-infrared spectroscopy cap on their head throughout the measurements
* Complete 1-back, 2-back test and Word Colour Stroop before, immediately after and 20 minutes after experimental/ control condition
* Have their blood pressure, heart rate taken by a smartwatch
* Complete a daytime sleepiness questionnaire and a back pain questionnaire


Eligibility criteria: Inclusion Criteria:

* NTU-NIE university student, between 21 and 30 years old, do not meet physical activity guidelines (150 mins of weekly MVPA)

Exclusion Criteria:

* taking blood-pressure lowering medication
* physically active (150 mins or more of weekly MVPA)
* deemed not physically fit to participate in physical activity based on responses to Get Active Questionnaire

Primary outcomes:
measure: 1-back test accuracy (%)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: 1-back test reaction time (ms)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: 2-back test accuracy (%)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: 2-back test reaction time (ms)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: Colour Word Stroop test accuracy (congruent) (%)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: Colour Word Stroop test accuracy (incongruent) (%)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: Colour Word Stroop test reaction time (congruent) (ms)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: Colour Word Stroop test reaction time (incongruent) (ms)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: pre-frontal cortical oxygenated hemoglobin levels (micrometre)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
measure: pre-frontal cortical deoxygenated hemoglobin levels (micrometre)
timeFrame: Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)
Secondary outcomes:
Other outcomes:
Locations:
city: Singapore
country: Singapore
facility: Block 5 Physical Education and Sport Science
Study officials:
References: