Clinical trial NCT04557592: Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs
Official title: Comparisons of gaIt aNalyses pERformance Between the Gaitrite walkwaYs
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Gait Apraxia
Alzheimer Disease
Impaired Cognition
Lead sponsor: University Hospital, Angers
Sponsor class: OTHER_GOV
First posted: 2020-09-21
Enrollment: 98
Sex: ALL
Minimum age (years): 74
Standard ages: OLDER_ADULT
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All consecutive patients meeting the eligibility criteria over the study period.

Brief summary: The GAITRite® system is an instrumented with resistive pressure sensors gait analyzer. It was first validate in 2001 against paper-and-pencil (intraclass correlation coefficient \[ICC\] \> 95%) for spatial measures and against video-based (ICC \> 93%) for temporal measures, and was thus a reliable tools to measure step lengths and times in both walkway center and left-of-center measurements. It was considered as one of the gold standards in gait analyses. This gait analyze system may distinguish prospectively faller and non-faller older adults, but it can detect spatial, temporal, and spatiotemporal measures of gait and greater variability of gait parameters which were associated with and predictive of both global- and domain-specific cognitive decline. Moreover, spatiotemporal gait parameters analyzed using GAITRite® were more disturbed in the advanced stages of dementia, and more affected in the non-AD dementia than in AD suggesting that quantitative gait parameters could be used as a surrogate marker for improving the diagnosis of dementia.

Nevertheless, GAITRite® is not a unique system and it comprises different walkways. One of these technologies was a roll-up system (platinum plus classic, RE, Basic and Safari), and the other was a system composed by a changeable association of plates (CIRFACE). In order to ensure a good comparability between studies using these different walkways, it appears important to compare the performances of these walkways in gait analysis. Thus, the main aim of this study was to compare the performances in gait analyze between the GAITRite® platinum plus classic and the GAITRite® CIRFACE among older adults. Secondary aims were to compare these parameters among patients with cognitive complaint, minor or major neurocognitive disorder (NCD) related to Alzheimer disease.


Eligibility criteria: Inclusion Criteria:

* Age ≥ 75 years
* Gait analysis performed with the two walkways superimposed during a consultation or day hospitalization

Exclusion Criteria:

* Opposition to the use of the information collected for research purposes

Primary outcomes:
measure: Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices
timeFrame: baseline
measure: Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices
timeFrame: baseline
measure: Change in spatiotemporal gait, and in particular in the variability of stride time between the two devices
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Angers
country: France
facility: Angers University Hospital
Study officials:
References: