Clinical trial NCT06501729: Kissing As a Protective Factor Against Acidic PH in Saliva
Official title: Potential Effect of Oral Kissing Between Two People Against the Decrease in PH
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Dental Caries
Tooth Demineralization
Teeth Erosion Limited to the Enamel
Keywords: Saliva
Hydrogen-Ion Concentration
dental caries
Lead sponsor: Universidad Catolica Santiago de Guayaquil
Sponsor class: OTHER
First posted: 2024-07-15
Enrollment: 45
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SEQUENTIAL
Intervention model description: The couples in the control group will not kiss; they will only wait for the salivary pH to neutralize physiologically. The other couples will be divided into two groups: the group in which only one person in the couple consumes the sugary or fermented drink, and the group in which both people in the couple do so.
Primary purpose: PREVENTION

Brief summary: The pH of saliva can be acidic or alkaline; When it is acidic, the tooth enamel is demineralized, that is, weakened. Additionally, bacteria in the mouth can increase and cause infections such as cavities. This occurs when we consume sugary or fermented drinks, such as soda or beer.

The intention of the research team is to give some of these drinks to the study participants and verify the decrease in salivary pH. Next, a group of people will be asked to kiss their partner on the mouth, and then the pH will be measured again to see if it increases, that is, if it stops being acidic faster than in the group that did not kiss.

The aim is to demonstrate that kissing on the mouth between two people can protect teeth from cavities by rapidly increasing the pH of saliva after it has decreased to become acidic.

Detailed description: The goal of this intervention study will be to determine if oral kissing between two people can increase salivary pH more quickly after drinking artificial juices, soft drinks, or (non-alcoholic) beers. It will also be studied whether the pH restoration time is faster when only one person kisses one of the named drinks or when both people do it. The main questions that are intended to be answered are the following:

* Is the act of kissing on the mouth capable of increasing the pH of saliva more quickly than physiologically after consuming a sugary or fermented drink that has decreased it?
* Is the increase in salivary pH after an oral kiss more accelerated when only one person consumes sugary or fermented drinks than when both people do so? The investigators will measure the basal pH of all participants before providing them with one of the drinks (artificial fruit juice, soda, or non-alcoholic beer). The researchers will then give the drinks and measure the decrease in salivary pH in all groups. Control group participants will not kiss; They will only wait for the salivary pH to neutralize physiologically. The rest of the couples will be divided into two groups: the group in which only one person in the couple consumes the sugary or fermented drink, and the group in which both people in the couple do so.

Saliva pH measurements will be performed, after initiation and consumption of the drinks, every 5 minutes for up to 40 minutes. That is, until the restoration of salivary pH is ensured in all groups.

Participants:

* They will be between 18 and 30 years old to reduce the probability of consuming medications that alter salivary pH.
* They should not be taking medications that alter the pH of saliva.
* They must be in good health.
* They should not have abscesses in the oral cavity.
* They must have good oral health according to the loss proposed and the observed index.

Eligibility criteria: Inclusion Criteria:

* They must be in good health
* They must have good oral health according to the raised loss and observed index.
* They will be between 18 and 30 years old to reduce the probability of consuming medications that alter salivary pH.

Exclusion Criteria:

* Be taking medications that alter the pH of saliva.
* Have abscesses in the oral cavity

Primary outcomes:
measure: salivary pH
timeFrame: In a period of every 5 minutes, until reaching 40 minutes, which is the time in which physiologically the pH of the saliva is neutralized.
Secondary outcomes:
Other outcomes:
Locations:
city: Guayaquil
country: Ecuador
facility: School of Dentistry of the Catholic University Santiago de Guayaquil
state: Guayas
Study officials:
References:
citation: Uma E, Theng KS, Yi LLH, Yun LH, Varghese E, Soe HHK. Comparison of Salivary pH Changes after Consumption of Two Sweetened Malaysian Local Drinks among Individuals with Low Caries Experience: A Pilot Study. Malays J Med Sci. 2018 Jul;25(4):100-111. doi: 10.21315/mjms2018.25.4.10. Epub 2018 Aug 30.