Clinical trial NCT03905122: Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method
Official title: Investigation of the Effects of Continuous Venous Dialysis and Hemodialysis on Fluid Dynamics by Bioreactance Method
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Renal Dialysis
Lead sponsor: Trakya University
Sponsor class: OTHER
First posted: 2019-04-05
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients in need of dialysis treatment

Brief summary: Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Detailed description: Dialysis methods applied at the bedside and dialysis methods applied in hemodialysis unit are widely applied in patients with renal insufficiency. Especially hemodynamically affected patients are less affected by hemodynamics as a result of using dialysis methods. Dialysis in the hemodialysis unit is a method used in intensive care patients and is preferred especially in patients with stable hemodynamics. In dialysis methods, changes occur frequently in the body fluids of the patient. It is a completely non-invasive method by bioreactance method and it can be done to measure the intra-body fluid status with the help of the glued probes. The aim of this study is to investigate the effects of continuous venous dialysis and hemodialysis on the fluid dynamics applied at the bedside with bioreactance method. As a result of measurements with buioreactans method, fluid balance in patients will be understood more easily. In this way, the patient can develop more comfortable hemodynamic changes. Patients in the Surgery, Reanimation and Postoperative Intensive Care Unit with more than 24 hours of hospitalization and bedside dialysis or hemodialysis will be included in the study. Before the dialysis, body fluid measurements will be made with bioreactance, and after dialysis in patients receiving hemodialysis, and in dialysis patients 6, 12, 24 and 36 hours.

Eligibility criteria: Inclusion Criteria:

* patients required dialysis therapy

Exclusion Criteria:

* under 18 years old
* confirmed or undiagnosed brain death

Primary outcomes:
measure: change in thoracic fluid content
timeFrame: before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
measure: change in Cardiac Output
timeFrame: before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
measure: change in Cardiac Index
timeFrame: before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
measure: change in stroke volum
timeFrame: before and after hemodialysis therapy, before bedside continous venovenous dialysis therapy and 6,12,24 and 36. hours
Secondary outcomes:
Other outcomes:
Locations:
city: Edirne
country: Turkey
facility: Trakya University
Study officials:
affiliation: Trakya University, Edirne
name: Ahmet Senol Uyar, Specialist
role: PRINCIPAL_INVESTIGATOR
References: