Clinical trial NCT03120169: Effects of Treadmill Versus Cycling Endurance Training in Patients With COPD
Official title: Effects of a Three Week Treadmill Versus Cycling Endurance Training on Balance, Gait Performance and Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease - a Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: COPD
exercise
training
cycling
treadmill
walking
pulmonary rehabilitation
Lead sponsor: Schön Klinik Berchtesgadener Land
Sponsor class: OTHER
First posted: 2017-04-19
Enrollment: 30
Sex: ALL
Minimum age (years): 50
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Aim of this study is to investigate the effects of treadmill versus cycling endurance training on Balance, gait performance and exercise capacity in patients with severe chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized into one of two intervention groups. Walking intensity in the treadmill group will be set at 80 percent of the average speed of the 6-minute walking test. The cycling group will exercise at an intensity of 60 percent according to an Initial incremental cycling test.

Patients will perform 5 to 6 training sessions per week. The total exercise duration will be progressively increased from 10 to 30 minutes. Walking or cycling intensity will also be progressively increased if perceived exertion during exercise is rated below 3 on the modified 10-point Borg scale.


Eligibility criteria: Inclusion Criteria:

* COPD Stage III or IV according to the global initiative for chronic obstructive lung disease
* impaired exercise capacity (6 Minute walk distance of less than 70% of the reference values from Troosters et al.)

Exclusion Criteria:

* acute, severe exacerbation of COPD
* carbon dioxide of more than 45 mmHg at rest
* any disabilities that prevent patient form walking or cycling
* Patient is not able to walk 20 meters without any aid (for example rollator)

Primary outcomes:
measure: Change in step symmetry during 20m walking
timeFrame: measurement on day 1 and 21
Secondary outcomes:
measure: Change in balance performance during semi-tandem stance
timeFrame: measurement on day 1 and 21
measure: Change in balance performance during Romberg stance
timeFrame: measurement on day 1 and 21
measure: Change in balance performance during single leg stance
timeFrame: measurement on day 1 and 21
measure: Change in muscle power during counter movement jump
timeFrame: measurement on day 1 and 21
measure: Change in 1 Minute sit to stand test
timeFrame: measurement on day 1 and 21
measure: Change in 5 Repetition sit to stand test
timeFrame: measurement on day 1 and 21
measure: Change in peak muscle strength
timeFrame: measurement on day 1 and 21
measure: Change in 4 meter gait Speed test
timeFrame: measurement on day 1 and 21
measure: Change in 6-minute Walk test
timeFrame: measurement on day 1 and 21
measure: Change in Hospital anxiety and Depression scale
timeFrame: measurement on day 1 and 21
Other outcomes:
Locations:
city: Schoenau Am Koenigssee
country: Germany
facility: Schoen Klinik Berchtesgadener Land
Study officials:
References: