Clinical trial NCT06711263: Role of Herbal Based Mouthwashes in Plaque Control
Official title: Role of Herbal Based Mouthwashes in Plaque Control. a Randomized Clinical Control Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Plaque Induced Gingival Disease
Keywords: plaque
gingival bleeding
resveratrol
miswak
tea tree oil
chlorhexidine
Lead sponsor: Ajman University
Sponsor class: OTHER
First posted: 2024-12-02
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: In the Initial Visit-Baseline, and subsequent visits, participants will be called in the morning. Morning hours will be chosen for examination, as it will reduce the risk of bias and also help in quantifying results. plaque and gingival scores will be recorded and the First herbal mouthwashes will be given, participants will also be provided new tooth-brushes (Oral B-soft).
Primary purpose: SCREENING

Brief summary: Herbal medicine has been used for thousands of years. Traditional herbal medicine is used by an estimated 80% of the world's population for primary health care. Herbal treatments have gained popularity as a dietary supplement for illness prevention and as an alternative/complementary therapy in recent years. Herbal remedies come in a wide variety of forms and can be found on the market all over the world.

Detailed description: Herbal mouthwashes have been increasingly popular over time. Ethnomedicines are the term used to describe them. Various substances have been tested, with phytopharmacological analyses yielding contradictory results. Many previous studies had tested the antiplaque efficiency of one herbal mouthwash with contradicting results, other studies have tested the Antiplaque efficiency of chlorhexidine, tea tree oil and Miswak, some studies had given positive outcomes and benefits of Miswak on the gingiva and others when comparing between the efficacy of Miswak over chlorhexidine mouth wash in dental practice provided results favouring both these mouthwashes.

In our proposed study we will compare the antiplaque efficiency of three herbal kinds of mouthwash, Miswak, tea tree oil and Resveratrol mouthwash. Plaque and gingival bleeding scores will be taken before the study from 6 different teeth and retaken after 2 weeks and four weeks respectively the use of the mouthwash. This study is single-blinded. Antiplaque and gingival bleeding scores from the three mouthwashes will be recorded over a period of a month and statistical analysis will be performed

Eligibility criteria: Inclusion Criteria:

* Patients who are medically fit
* Patients with gingival inflammation not progressed into periodontitis (AAP classification
* Patients between the age of 18-60 years

Exclusion Criteria:

* Patients who are medically compromised
* Patient who have undergone a periodontal therapy for the past 3 months
* Patients who are healthy but have been using herbal mouthwashes

Primary outcomes:
measure: plaque score
timeFrame: From Baseline-pre-intervention to the end of treatment at 4 weeks
Secondary outcomes:
measure: gingival bleeding score
timeFrame: from pre-intervention to the end of the treatment at 4 weeks
Other outcomes:
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