Clinical trial NCT06108804: Comparative Effects of Mulligan Pain Release Phenomenon With and Without Tapping in Patellofemoral Pain Syndrome
Official title: Comparative Effects of Mulligan Pain Release Phenomenon With and Without Tapping in Management of Patellofemoral Pain Syndrome
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Patellofemoral Pain Syndrome
Keywords: patellofemoral pain syndrome
mulligan's pain release phenomenon
tapping
kujala scale
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-10-31
Enrollment: 32
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: A parallel study is a type of clinical study in which two or more groups of participants receive different interventions.
Primary purpose: TREATMENT

Brief summary: The aim of this study is to compare the effects of mulligan pain release phenomenon with or without Tapping in management of Patellofemoral pain syndrome

Detailed description: Patellofemoral pain syndrome is a general phrase that refers to discomfort in the Patellofemoral joint and associated soft tissues, including the kneecap, tendons, and ligaments.

In 2019, a comparative study conducted. They pick 30 respondents randomly, who met the study's inclusion requirements and expressed a willingness to participate. They were split into two groups; fifteen subjects per group. Each group received treatment for four weeks, with sessions occurring every other day. PRP with Kinesiotaping is in Group A(n=15), and traditional therapy is in Group B(n=15). Both groups underwent ultrasonic treatment and VMO strengthening. Data analysis was carried out statistically using paired t tests within groups and unpaired t tests across groups. The study's findings indicated that both groups of therapy were successful, however PRP combined with Kinesiotaping significantly reduced pain and improved functional limits in patients with persistent Patellofemoral OA.

In 2020, a double blind RCT study conductred. Based on the mechanical correction approaches, 43 women with at least a 3-month history of PFPS were randomized into three groups: KT for patellar medialization, KT for lateral rotation of the femur and tibia, and the control group. The identical 12-week muscle- building and motor-control exercises were administered to all groups. The numerical pain rating scale (NPRS) at rest and during exertion, the kujala score (AKPS), and the single jump hop test were used to assess knee pain and function at baseline, at 6 weeks, at the end of therapy (12 weeks), and during the 12-week follow-up. Results of the study showed that, in the 6-week and 12-week follow-ups, there were clinically significant differences between the KT with lateral rotation of femur and tibia and the control group in terms of the AKPS and NPRS scores during effort. Pain and function significantly improved in all groups (within group).

Patellofemoral pain syndrome is a prevalent issue among the adults due to prolong sitting, ascending or descending stairs frequently, crouching and walking. The majority of research studies have primarily focused on other age groups, such as older adults or adolescents and very little study was done regarding this issue among young adults. To the best of our knowledge although in the past many studies have worked on mulligan pain release phenomenon with mobilization, or exercise therapy have been practiced in the treatment of Patellofemoral pain syndrome were found effective individually, but there is a lack of comprehensive studies including randomized clinical trials directly comparing the mulligan pain release phenomenon with or without taping on management of Patellofemoral pain syndrome. This RCT will aims to evaluate the effectiveness of two commonly utilized techniques, Mulligan pain release phenomenon and taping will ascertain that if two of these, Mulligan pain release phenomenon and taping, may have different effects on the Patellofemoral pain syndrome, knee range of motion and pain in young population with PFPS.

Eligibility criteria: Inclusion Criteria:

* Age 20 to 40 years
* Both male and female
* NPRS\>3
* AKPS ≥6
* ROM\<135 ° rarely. Knee range of motion is usually normal in patients of Patellofemoral pain syndrome.
* Positive patellar grind test
* Adults having anterior knee pain from previous duration of 2-3 months which is aggravated by walking, stairs ambulation or prolong sitting.

Exclusion Criteria:

* Recent fracture/trauma
* Acute diseased condition
* Knee surgery
* Tumor or infection around the knee
* Rheumatoid Arthritis
* Pregnancy
* Any malformation or joint hypermobility
* patellar tendon pathology

Primary outcomes:
measure: Numeric Pain Rating Scale
timeFrame: 4th week
measure: Knee Flexion Range of Motion
timeFrame: 4th week
measure: Knee Extension Range of Motion
timeFrame: 4th week
measure: Kujala Score (AKPS)
timeFrame: 4th week
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Kot Khawaja Saeed Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Humera Mubashar, MS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Chang WD, Chen FC, Lee CL, Lin HY, Lai PT. Effects of Kinesio Taping versus McConnell Taping for Patellofemoral Pain Syndrome: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2015;2015:471208. doi: 10.1155/2015/471208. Epub 2015 Jun 21.
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citation: Taunton JE, Ryan MB, Clement DB, McKenzie DC, Lloyd-Smith DR, Zumbo BD. A retrospective case-control analysis of 2002 running injuries. Br J Sports Med. 2002 Apr;36(2):95-101. doi: 10.1136/bjsm.36.2.95.
citation: Pal S, Draper CE, Fredericson M, Gold GE, Delp SL, Beaupre GS, Besier TF. Patellar maltracking correlates with vastus medialis activation delay in patellofemoral pain patients. Am J Sports Med. 2011 Mar;39(3):590-8. doi: 10.1177/0363546510384233. Epub 2010 Nov 12.
citation: Leibbrandt DC, Louw QA. The use of McConnell taping to correct abnormal biomechanics and muscle activation patterns in subjects with anterior knee pain: a systematic review. J Phys Ther Sci. 2015 Jul;27(7):2395-404. doi: 10.1589/jpts.27.2395. Epub 2015 Jul 22.
citation: Logan CA, Bhashyam AR, Tisosky AJ, Haber DB, Jorgensen A, Roy A, Provencher MT. Systematic Review of the Effect of Taping Techniques on Patellofemoral Pain Syndrome. Sports Health. 2017 Sep/Oct;9(5):456-461. doi: 10.1177/1941738117710938. Epub 2017 Jun 15.
citation: Arrebola LS, Teixeira de Carvalho R, Lam Wun PY, Rizzi de Oliveira P, Firmo Dos Santos J, Coutinho de Oliveira VG, Pinfildi CE. Investigation of different application techniques for Kinesio Taping(R) with an accompanying exercise protocol for improvement of pain and functionality in patients with patellofemoral pain syndrome: A pilot study. J Bodyw Mov Ther. 2020 Jan;24(1):47-55. doi: 10.1016/j.jbmt.2019.05.022. Epub 2019 May 22.