Clinical trial NCT06578663: Electrical Dry Needling Versus Iontophoresis in Treating Chronic Unilateral Knee Osteoarthritis
Official title: Electrical Dry Needling Versus Iontophoresis in Treating Chronic Unilateral Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Osteoarthritis of Knee
Lead sponsor: Horus University
Sponsor class: OTHER
First posted: 2024-08-29
Enrollment: 60
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized controlled trail, repeated measured; pre and post-test experimental design will be conducted
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to compare the effects of electrical dry needling versus glucosamine sulfate iontophoresis on pain intensity level, functional ability, and knee range of motion in chronic unilateral knee osteoarthritis patients.

Detailed description: Knee Osteoarthritis (OA) is a chronic disease affecting 240 million people worldwide, with a higher prevalence in older adults. The disease leads to knee deformity, laxity, and ligament instability. Dry needling, a new treatment modality, uses needle electrodes to deliver an electric current to the pain-generating trigger point, improving the physiological effects and analgesic and anesthetic effects. Iontophoresis, a safer method of drug therapy, has shown to be more effective in pain reduction in knee osteoarthritic patients. The study aims to investigate the effect of electrical dry needling versus glucosamine sulfate iontophoresis on pain intensity level, knee function, and range of motion (ROM) in chronic knee OA patients. This approach aims to maximize drug bioavailability, optimize therapeutic efficacy, and minimize side effects.

Eligibility criteria: Inclusion Criteria:

1. The patient will be selected from the outpatient clinic of physical therapy at Horus University, New Damietta, Egypt, diagnosed with a Kellgren/Lawrence grade 2,3 radiological severity of knee osteoarthritis (OA). and referred by an orthopedist.
2. Age will range from 40 to 60 years.
3. Body mass index will range from 25 to 29.9 kg/m2.
4. Duration of knee pain not less than 3 months prior to study .

Exclusion Criteria:

1. Patients with history of cardiac disorder with pacemaker.
2. Knee surgery.
3. Diabetes and nutritional disorder.
4. Neuromuscular and other musculoskeletal diseases.
5. Any red flags to dry needling, or conventional therapy.
6. Had received physical therapy, acupuncture, massage therapy, chiropractic, or intra-articular injections for the painful knee in the last 3 months.
7. Presented with positive neurological signs.

Primary outcomes:
measure: Pain intensity level measurement
timeFrame: at baseline and after 6 weeks
measure: Functional ability measurement
timeFrame: at baseline and after 6 weeks
measure: Knee ROM measurement
timeFrame: at baseline and after 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Damieta
country: Egypt
facility: out-patient clinic, faculty of physical therapy, Horus university
Study officials:
References: