Clinical trial NCT05491096: Effects of Proprioceptive Neuromuscular Training on Sensory and Motor Function in Guillain Barre Syndrome
Official title: Comparison of Effects of Proprioceptive Neuromuscular Training on Sensory Versus Motor Function in Patients With Guillain Barre Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Guillain-Barre Syndrome
Keywords: Guillain Barre Syndrome
Proprioceptive Neuromuscular Training
Balance
Motor Function
Sensory Function
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-08-08
Enrollment: 26
Sex: ALL
Minimum age (years): 10
Maximum age (years): 25
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study aims to determine the effects of Proprioceptive Neuromuscular Training on Sensory versus Motor Function in patients presenting with Guillain Barre Syndrome.

Detailed description: This study will be a randomized controlled trial and will be conducted to determine the effects of proprioceptive neuro-muscular training on sensory and motor function of lower limb,In this study data will be collected from multiple Hospitals of Lahore via Berg Balance Scale, Timed Up and Go test One Leg Stance test before and after intervention. Non- probability convenient sampling technique will be used to enroll 26 patients in total. The patients will be randomly allocated into two groups through lottery method, to either the proprioceptive training group or control group.Both groups will be assessed for proprioception via lower extremity position test as a baseline. Proprioception training programme will be implemented in experimental group and will be carried out for eight weeks, with three (60-minute) sessions per week. It will start with 10 minutes of Warm-up. This will be followed by 30 minutes of proprioceptive exercises targeting lower extremities. Proprioceptive exercises will be divided into three components, standing on Foam with eyes open and eyes closed and passing any object from one subject to the other for 10 minutes, throwing and catching a ball will be performed while standing on foam for additional 10 minutes, throwing and catching a ball, will be performed on trampoline to further challenge the balance system. After each set of 10-minute exercise, the subjects will be given two-minute resting periods. In the end, 10 minutes will be given for cool down exercises to bring the heart rate back to resting level. All participants in both groups will be evaluated before and after the treatment programs. Data will be analyzed by using Statistical Package of Social Sciences Version 26.

Eligibility criteria: Inclusion Criteria:

1. Diagnosed with Guillain Barre Syndrome already taking treatments
2. Inflammatory Demyelinating Guillain Barre Syndrome patients
3. Acute motor sensory axonal neuropathy
4. Guillain Barre Syndrome patients in the subacute phase
5. Guillain Barre Syndrome patients with impaired proprioception
6. Patients with Glasgow Coma Scale above 12

Exclusion Criteria:

1. Other Guillain Barre Syndrome types
2. Spinal cord injury
3. Traumatic neuritis
4. Not Fulfilling Above Criteria Of Age

Primary outcomes:
measure: Berg Balance Scale
timeFrame: 12th Week
measure: Time up and go test
timeFrame: 12th Week
measure: One leg stance test
timeFrame: 12th Week
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: psrd (pakistan Society for the rehabilitation of the disabled)
state: Punjab
Study officials:
affiliation: Riphah International University
name: Sara Aabroo
role: PRINCIPAL_INVESTIGATOR
References: