Clinical trial NCT03716882: Acoustic Structures Crying of Infants From 1 to 4 Months and Their Signification
Official title: Acoustic Structures Crying of Infants From 1 to 4 Months and Their Signification
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Infants
Keywords: Infants
Principal Component 1 (PC1)
Principal Component 2 (PC2)
Song Meter 4
Acoustic structures crying
PRAAT software
Lead sponsor: Centre Hospitalier Universitaire de Saint Etienne
Sponsor class: OTHER
Collaborators: name: ENES, CNRS 9197
First posted: 2018-10-23
Enrollment: 25
Sex: ALL
Minimum age (years): 1
Maximum age (years): 10
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Infants at the birth

Brief summary: Crying is a survival mechanism for babies and their almost exclusive means of expression until the age of 4 months. Babies 'cry is mostly related to pain, a feeling of hunger, discomfort or separation following the departure of a parent around. Crying is a complex but essential means of communication and information between a baby and his parents that raises the question of their meaning.

The cry phenomenon consists of complex acoustic signals produced by the vocal cords and filtered by the vocal tract. The vibrations frequency determines the fundamental frequency, itself responsible for the perception of the cry tone (pitch). The frequency spectrum of a cry is modified during the passage through the upper airways forming broad bands called "resonance frequency" or "formants".

From the specificity of a crying sequence, it is possible to extract dynamic information and relate it to the perception that the adult has of it. Thus dynamic crying is often perceived by the adult as an imminent need of the baby.

Some studies have shown that a child's crying may change according to his degree of discomfort, suggesting that crying was a "graduated signal" whose frequency and timbre could vary along a continuum. These changes would explain why adult listeners would be able to dissociate crying babies of different intensities.

Conversely, an inappropriate response to crying could gradually generate disorders of the relationship between the baby and the parent.

However, despite their potential neuro-ethological interest, knowledge of information transmitted by babies's cry remains superficial. This could be related to the relatively obsolete techniques of recording or due to the lack of objective physiological data on babies 'cry. Finally, the perception and reactions of adults when they hear crying babies are not fully understood.

Detailed description: The objective of this study is to evaluate acoustic structures crying of infants from 1 to 4 months for to study individual acoustic signature.

Eligibility criteria: Inclusion Criteria:

* any safe term infants (\> 37SA)
* eutrophic and in good health
* infants sleeping in bed with bars without baby nest
* form signed by the holder of parental authority.
* Parents affiliated to a social security scheme
* Parents who to live in cities of Saint-Etienne, Villars, Saint Priest-en-Jarez, Etrat and Saint Jean-Bonnefonds, France

Exclusion Criteria:

* inter-uterine growth restriction
* antenatal neurological pathologies or at birth
* perinatal asphyxial encephalopathy
* antenatal pathologies (e.g. trisomy 21, hydrocephalus...)
* multiple pregnancy

Primary outcomes:
measure: Acoustic structures crying of parameters Principal Component 1 (PC1) and Principal Component 2 (PC2)
timeFrame: up to 3 and half months.
Secondary outcomes:
measure: Questionnaire of cry in infant
timeFrame: up to 3 and half months.
Other outcomes:
Locations:
city: Saint-Étienne
country: France
facility: Chu Saint-Etienne
Study officials:
affiliation: Université Jean MONNET, Saint-Etienne, France
name: Nicolas MATHEVON, PhD
role: STUDY_CHAIR
References: