Clinical trial NCT00073346: Pilot Trial of Cognitive and Behavioral Treatment of Compulsive Hoarding Compared to Wait List Control
Official title: Cognitive and Behavioral Treatment of Compulsive Hoarding
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Obsessive-Compulsive Disorder
Keywords: Hoarding Disorder
Lead sponsor: Boston University Charles River Campus
Sponsor class: OTHER
Collaborators: name: National Institute of Mental Health (NIMH)
First posted: 2003-11-21
Enrollment: 52
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: active treatment versus wait list control
Primary purpose: TREATMENT

Brief summary: This study developed and tested a specialized cognitive and behavioral treatment for the symptoms of hoarding disorder, including excessive acquiring, difficulty discarding items, and extensive clutter in the home.

Detailed description: Compulsive hoarding is characterized by excessive acquisition of possessions, difficulty discarding possessions, and excessive clutter. This condition is resistant to standard pharmacological and psychotherapeutic interventions that have proven effective in treating other obsessive compulsive spectrum disorders. This study aimed to determine the effectiveness of a specialized cognitive behavioral therapy (CBT) designed for treating hoarding symptoms.

This study consists of three phases. In Phase 1, pilot data from previous studies were examined to develop an intervention suitable for use in a waitlist trial. In Phase 2, pilot study information were used to develop and test a treatment manual for compulsive hoarding. During this phase, treatment was applied flexibly to allow for variations in treatment duration and choice of techniques. During Phase 3, participants were randomly assigned to 26 weekly sessions of CBT or to a 12-week wait-list control, followed by active treatment for a fixed duration of 26 sessions. Therapist adherence and competence were assessed through audiotaped therapy sessions.

Eligibility criteria: Inclusion criteria:

* Display at least moderately severe hoarding symptoms
* Must live within 45 minutes of Boston, MA or Hartford, CT

Exclusion criteria:

* Ten or more sessions of cognitive behavior therapy for hoarding
* Concurrent psychotherapy or medications
* Suicidal, psychotic, or other psychiatric symptoms requiring hospitalization
* Compulsive buying symptoms that are part of a manic phase of bipolar disorder
* Mental retardation, dementia, brain damage, or other cognitive dysfunction that would interfere with the study

Primary outcomes:
measure: Saving Inventory-Revised
timeFrame: change from baseline to week 12; change from baseline to week 26
Secondary outcomes:
measure: Hoarding Rating Scale
timeFrame: change from baseline to week 12; change from baseline to week 26
Other outcomes:
Locations:
city: Hartford
country: United States
facility: Hartford Hospital, Institute of Living
state: Connecticut
city: Boston
country: United States
facility: BostonUCRC
state: Massachusetts
Study officials:
affiliation: Boston University
name: Gail Steketee
role: PRINCIPAL_INVESTIGATOR
References: