Clinical trial NCT07014787: Assessing the Effect of Different Grades of Chondromalacia on Static and Dynamic Balance Using Biodex Balance System
Official title: EFFECT OF GRADES OF CHONDROMALACIA ON STATIC AND DYNAMIC BALANCE: CROSS-SECTIONAL STUDY
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Chondromalacia Patella
Keywords: Biodex balance system static and dynamic balance assessment of chondromalacia
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-06-11
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 100 patients, 80 with different grades of chondromalacia (Grade I, II, III, IV) with 20 participants in each group and 20 healthy participants in the control group will be recruited for the study.

Brief summary: The aim of this study is to investigate the effect of grades of chondromalacia on static and dynamic balance.

Detailed description: Chondromalacia patellae is a very common disorder which is characterized by softening, swelling, fraying, fissuring, and erosion of hyaline cartilage overlying the patella. Patellar chondromalacia could be observed as a cause of patellofemoral pain, as well as in patients with osteoarthritis, in patients with knee trauma, or even in asymptomatic patients.

Balance, as an essential function in human daily life and activities, can be defined as central nervous system input. Postural control can be divided into static balance and dynamic balance; static balance controls the oscillation amplitude of the body, and dynamic balance uses the body's internal and external information to analyze factors that influence the stability of interference (Such as walking, pushing and pulling),and to maintain postural control. The perfect combination of static and dynamic balance is key to normal activities of the human daily life.

100 patients, 80 with different grades of chondromalacia (Grade I, II, III, IV) with 20 participants in each group and 20 healthy participants in the control group will be recruited for the study to assess the effect of different chondromalacia grades on static and dynamic balance.

Eligibility criteria: Inclusion Criteria:

1. Age ranged from 18 to 40 years old
2. groups include both males and females
3. Patients with Grade I, II, III and IV chondromalacia: Confirmation of diagnosis by MRI
4. BMI will be ranged from 19.0 to 29.0
5. Patients with Unilateral or bilateral chondromalacia.
6. Chronic cases for more than 3 months.
7. Positive sign of Knee pain according to patellar Grind Test

Exclusion Criteria:

1. patients have not undergone knee replacement.
2. patients have not done Intra-articular injection in the affected knee for the past 3 months.
3. Patients with rheumatoid arthritis or other inflammatory arthritis.
4. Patients with Vestibular disorders or neurological conditions.

Primary outcomes:
measure: Measuring static and dynamic balance
timeFrame: up to four weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Faculty of physical therapy Cairo University
Study officials:
affiliation: Cairo University
name: Selwan Khaled Ayad, Teacher Assistant
role: PRINCIPAL_INVESTIGATOR
References: