Clinical trial NCT04357145: Exercise Dosages and Exercise Adherence With Patients With Knee Osteoarthritis
Official title: The Effect of Different Exercise Dosages on Exercise Adherence, Pain and Functionality in Patients With Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Knee Osteoarthritis
Exercise Adherence
Exercise Dosage
Home Exercises
Lead sponsor: Marmara University
Sponsor class: OTHER
First posted: 2020-04-22
Enrollment: 60
Sex: ALL
Minimum age (years): 40
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Although the effects of different exercise dosages for patients with osteoarthritis are compared in the literature, it is seen that studies on which exercise dosage is better are insufficient.The planned study has 2 main objectives:

* To examine the effects of different exercise dosages on exercise dependence
* To investigate the effect of different exercise dosages on pain and functional results

Detailed description: Knee osteoarthritis (KO) is the most common musculoskeletal problem worldwide, leading to pain and loss of locomotor function. The Framingham Osteoarthritis Study shows that 19% of adults have radiographic effects on the knee joint. Individuals with advanced symptomatic KO have difficulties in their daily life activities. Among all diseases, KO most affects activities such as walking, climbing stairs and housework. A wide range of physiotherapy treatment methods are available in KO treatment such as strengthening exercises, aquatic exercises, aerobic exercises, proprioception exercise, orthotics, taping methods and the use of electrophysiological agents. High-quality evidences suggests that land-based exercise therapy maintains its positive effect on pain, quality of life and functionality for 2-6 months after the treatment. The dosage of exercise therapy can be adjusted by the duration, frequency, or resistance of the exercise. However, evidence-based information on exercise dosage is limited in KO treatment. While KO is treated in physiotherapy clinics, it is also supported by home exercises during and after treatment. However, it is a clinical problem that patients show low adherence to home exercise. With this study, it is aimed to compare the exercise adherence of patients who are given home exercise with different exercise dosages and to show their functional results. Participants with KO aged between 40-85 years will be included in the study and randomly divided into two groups. The number of repetitions of the high dosage exercise group will be 2 times more than standard exercise group. Participants will be asked to apply home exercise programs 4 times a week. Exercise adherence, pain, kinesiophobia and functionality will be evaluated. Our study will be the first to demonstrate the effect of different home exercise dosages on exercise adherence. The information to be obtained with this study is thought to contribute to the preparation of a better home exercise program. With the information to be obtained through this study, it can contribute to the preparation of a better home exercise program.The planned study has 2 main objectives:

* To examine the effects of different exercise dosages on exercise dependence
* To investigate the effect of different exercise dosages on pain and functional results

Eligibility criteria: Inclusion Criteria:

* Having a diagnosis of unilateral or bilateral knee osteoarthritis.
* Being between stage 1-3 according to Kellgren-Lawrence criteria.
* Having at least 3 months of pain duration and decreased functioning.
* Being a volunteer who can read and write

Exclusion Criteria:

* Physiotherapy or other conservative therapy during the previous 3 months or a history of major knee trauma.
* Having Inflammatory joint disease, hip symptoms more aggravating than the knee symptoms,
* Having comorbidities not allowing exercise such as cardiovascular, respiratory, systemic, or metabolic conditions limiting exercise tolerance.
* Participants with previously performed knee replacement surgery

Primary outcomes:
measure: Change from Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Points at 12 weeks
timeFrame: Baseline, Week 3, Week 6 and Week 12
measure: Change from Exercise Adherence (with Self Reported Exercise Diary) at 12 Weeks Percentages at 12 Weeks
timeFrame: Week 3, Week 6, Week 9, Week 12
measure: Change from Knee Osteoarthritis Exercise Adherence Scale Points at 12 Weeks
timeFrame: Week 3, Week 6, Week 9, Week 12
Secondary outcomes:
measure: Change from Visual Analogue Scale(for Pain) Points at 12 Weeks
timeFrame: Baseline, Week 3, Week 6 and Week 12
measure: Change from Tampa Scale for Kinesiophobia Points at 12 Weeks
timeFrame: Baseline, Week 3, Week 6 and Week 12
measure: Change from Timed Up&Go Test Score at 12 Weeks
timeFrame: Baseline, Week 3, Week 6 and Week 12
measure: Change from Timed 10 Meter Walk Test Score at 12 Weeks
timeFrame: Baseline, Week 3, Week 6 and Week 12
Other outcomes:
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