louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06260787: Clinical Profiles And In Vitro Fertilization Success
Official title: The Relationship Between Clinical Profiles And The Success Rate Of In Vitro Fertilization Patients - Experience From Indonesia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: in Vitro Fertilisation
Lead sponsor: Universitas Padjadjaran
Sponsor class: OTHER
First posted: 2024-02-15
Enrollment: 223
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: In vitro fertilisation patients undergoing treatment at our facility

Brief summary: This research was carried out to determine if the IVF patients' clinical profile were connected with how successful in their getting pregnant. This was a cross-sectional study which recruited all patients, performed at a major fertility clinic in Indonesia. Our data collection period spanned between January 2017 and December 2021.

Detailed description: This study was conducted to determine whether there is an association between the clinical profile of in vitro fertilization patients and the success of pregnancy after in vitro fertilization in infertility patients.

The research was a cross sectional study using total sampling method, conducted on 223 infertility patients who performed in vitro fertilization at a tertiary fertility center in Bandung, Indonesia within the period January 2017-December 2021. Secondary data using medical records was taken.

We aimed to identify associations between the patient's age, the male partner's age, infertility duration, IVF protocol, fresh/frozen embryo, various infertility etiologies and the pregnancy rate in IVF programs. A p-value \<0.05 is considered significant.

Eligibility criteria: Inclusion Criteria:

* medical record data for in vitro fertilization patients at our facility from January 1,2017 to December 31, 2021

Exclusion Criteria:

* incomplete patient medical record data.

Primary outcomes:
measure: Pregnancy rate
timeFrame: 5 years
Secondary outcomes:
Other outcomes:
Locations:
city: Bandung
country: Indonesia
facility: Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran
state: Jawa Barat
Study officials:
affiliation: Permanent Staff at the Department of Obstetrics and Gynecology, Universitas Padjadjaran
name: Hanom H Syam, M.D., Ph.D
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03714087: Occlusal Outcomes by OGS After a Finishing Protocol
Official title: OGS Scores After the Use of a New Finishing Protocol
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Malocclusion
Orthodontics
Keywords: Finishing protocol
Aligner
Lead sponsor: Universidad de Antioquia
Sponsor class: OTHER
First posted: 2018-10-22
Enrollment: 40
Sex: ALL
Minimum age (years): 14
Maximum age (years): 65
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: One historic control group (UDEA1)comparing with intervention group (UDEA2) ( before and after)
Primary purpose: TREATMENT

Brief summary: Evaluation of the effects of the implementation of a new finishing protocol in orthodontics patients

Detailed description: Patients who are being treated in the postgraduate orthodontic clinics and who meet the inclusion and exclusion criteria, will be subject to a detailed evaluation according to the OGS criteria and upon meeting the treatment completion criteria they will be placed an aligner with setup for 3 weeks. The scores obtained before and after the aligner will be compared with a historical control group The OGS score obtained for each group, will be compared and the impact of the protocol and the aligner will be evaluated

Eligibility criteria: Inclusion Criteria:

* Patients who completed the active phase of the bimaxillary orthodontic treatment in the Orthodontics Postgraduate Program of the UdeA by criteria of the treating clinician, during 2014 - 2018 period were included. Patients treated by using the UDEA1 finishing protocol (GC) and the UDEA 2 (GE) finishing protocol, which included aligners. All patients must have standardized diagnostic records at the end of the finishing phase (cast models and panoramic X-Rays) and must accepted to participate in the study voluntarily

Exclusion Criteria:

* Patients that require prosthetic, periodontal and / or surgical treatments or with systemic compromise that may influence the outcome of orthodontic treatment

Primary outcomes:
measure: OGS score
timeFrame: Through study completion, an average of 2 year
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT04507087: Documentary to Encourage Plant-based Eating
Official title: Randomized Controlled Trial of a Documentary to Encourage Plant-based Eating
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Eating Behavior
Lead sponsor: Stanford University
Sponsor class: OTHER
First posted: 2020-08-11
Enrollment: 650
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: This study will assess whether watching a documentary video about the health, environmental, and ethical consequences of eating meat and animal products reduces participants' self-reported intake of these items.

Detailed description: See detailed preregistration: https://osf.io/xrckh/registrations

Eligibility criteria: Inclusion Criteria:

* Participant is currently located in the United States
* Participant is at least 18 years old

Exclusion Criteria:

* Participant is located outside the United States
* Participant is less than 18 years old

Primary outcomes:
measure: Total meat and animal product consumption
timeFrame: Consumption over the 1-week time frame spanning approximately 1 week to 2 weeks after baseline data collection
Secondary outcomes:
measure: Total meat consumption
timeFrame: Consumption over the 1-week time frame spanning approximately 1 week to 2 weeks after baseline data collection
measure: Total animal product consumption
timeFrame: Consumption over the 1-week time frame spanning approximately 1 week to 2 weeks after baseline data collection
measure: Consumption of each of 8 individual categories of meats and animal products
timeFrame: Consumption over the 1-week time frame spanning approximately 1 week to 2 weeks after baseline data collection
measure: Total consumption of selected, healthy plant-based foods (ounces consumed over the past week)
timeFrame: Consumption over the 1-week time frame spanning approximately 1 week to 2 weeks after baseline data collection
Other outcomes:
measure: Perceived importance of health
timeFrame: 2 weeks after baseline data collection
measure: Perceived importance of environmental sustainability
timeFrame: 2 weeks after baseline data collection
measure: Perceived importance of animal welfare
timeFrame: 2 weeks after baseline data collection
measure: Speciesism
timeFrame: 2 weeks after baseline data collection
measure: Interest in animal welfare activism and reform
timeFrame: 2 weeks after baseline data collection
measure: Social dominance orientation
timeFrame: 2 weeks after baseline data collection
Locations:
city: Palo Alto
country: United States
facility: Maya Mathur
state: California
Study officials:
affiliation: Stanford University
name: Maya B Mathur, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02047487: After Induction Chemotherapy of DP Plus DDP Concurrent Radiotherapy With and Without Bevacizumab Study
Official title: Docetaxel (T), Cisplatin (P) After Induction Chemotherapy With and Without Cisplatin (P) Concurrent Radiotherapy (X) Plus Bevacizumab (B) Phase II Clinical Study
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Head and Neck Neoplasms
Lead sponsor: Chinese PLA General Hospital
Sponsor class: OTHER
First posted: 2014-01-28
Enrollment: 120
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients with pathological diagnosis of head and neck squamous cell carcinoma

Brief summary: This is a randomized, open controlled multicenter phase II clinical study. The SPSS statistical software estimation of sample size, selection of the initial treatment of locally advanced head and neck squamous cell carcinoma in 120 patients, such as to achieve the desired results, considering expanding the clinical, according to the proportion of 1:1 were randomly divided into two groups, all patients were taken, docetaxel + cisplatin 2 cycles of induction chemotherapy 、Concurrent chemoradiotherapy（tomotherapy+cisplatin）, The experimental group was added with AVASTIN.


Eligibility criteria: Inclusion Criteria:

Men and women are not limited, requirements of ECOG0-2, age 18-70 years old, pathological stage III (NCCN2012), had not received radiotherapy and chemotherapy, expected to survive more than 3 months, the routine testing, were in the normal range, signed the informed consent

Exclusion Criteria:

Do not meet the above criteria; allergic to docetaxel and AVASTIN, or metabolic disorders; associated with gastrointestinal bleeding, perforation and other serious diseases; severe liver disease, kidney disease, respiratory disease or unable to control diabetes, hypertension and other chronic disease; heart disease clinical symptoms; there is peripheral nervous system disorders or have obvious mental disorder and disorders of the central nervous system; active phase \>CTCAE2 clinical severe infection; a history of organ transplantation (including bone marrow transplantation of autologous peripheral stem cell transplantation); pregnant, lactating women, women of childbearing age and spouse refused to take effective means of contraception contraception; no legal capacity, continue to influence medical or ethical reasons for who

Primary outcomes:
measure: ORR
timeFrame: three month after ratiotherapy
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: PLAGH
city: Beijing
country: China
facility: PLA307
Study officials:
affiliation: Haidian District Fuxing Road, Beijing No. 28 Department of radiotherapy
name: j x li, doctor
role: STUDY_CHAIR
References:
Clinical trial NCT02451787: The 'Hidden' Biological Impact of Vitamin D Deficiency: a Biomarker Study; Part 2
Official title: The 'Hidden' Biological Impact of Vitamin D Deficiency: a Biomarker Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Vitamin D Deficiency
Lead sponsor: The Hong Kong Polytechnic University
Sponsor class: OTHER
First posted: 2015-05-22
Enrollment: 27
Sex: ALL
Minimum age (years): 18
Maximum age (years): 26
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: The investigators major aims are to: determine the vitamin D status of a group of young, apparently healthy adults in Hong Kong; examine inter-relationships between vitamin D status and biomarkers of DNA damage and repair, oxidative stress, inflammation and endothelial health; and, in part 2 of the study, investigate effects of improvement in vitamin D status on these biomarkers and other measures of well-being in those young adults shown to be deficient in vitamin D.

Detailed description: In this part 2 of the study the investigators will investigate the effect of vitamin D supplementation on biomarkers of these 'hidden' changes in apparently healthy young adults. The investigators will also explore the effect of improvement in vitamin D status in young apparently healthy adults in regard to muscular strength and response time, glucose control, a hormone that is linked to vitamin D (parathyroid hormone (PTH) ) and mood.

Eligibility criteria: Inclusion Criteria:

* apparently healthy, non-smokers
* non-obese
* found (in part1) to have low vitamin D status

Exclusion Criteria:

* chronic illness
* serious illness requiring medical treatment in previous 6 months
* pregnancy
* on regular medication or taking supplements on a regular basis

Primary outcomes:
measure: biomarkers of oxidative stress
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Hong Kong
country: Hong Kong
facility: The Hong Kong Polytechnic University
Study officials:
affiliation: The Hong Kong Polytechnic University
name: Iris F Benzie, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02424487: Intracuff Pressure During One-lung Ventilation in Infants and Children
Official title: Intracuff Pressure During One-lung Ventilation in Infants and Children
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: One-lung Ventilation (OLV)
Keywords: Initial pressure
changes of intracuff pressure
infants and children
Lead sponsor: Nationwide Children's Hospital
Sponsor class: OTHER
First posted: 2015-04-23
Enrollment: 30
Sex: ALL
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Male and female from 0-18 years old having thoracic surgery and requiring one-lung ventilation.

Brief summary: The purpose of this study is to evaluate the initial pressure and changes of the intracuff pressure during one-lung ventilation (OLV) in infants and children during thoracic surgery.


Eligibility criteria: Inclusion Criteria:

* Patients 0-18 yars old.
* Patients requiring intubation with a cuffed specialized endotracheal tube or bronchial blocker.
* Patients having thoracic surgery.
* Patients that require one-lung ventilation (OLV).

Exclusion Criteria:

* Patients that do not require to have cuffed specialized endotracheal tube or bronchial blocker.
* Patients not requiring one-lung ventilation.
* Patients not having thoracic surgery.

Primary outcomes:
measure: Intracuff pressure during OLV
timeFrame: intraoperative
Secondary outcomes:
Other outcomes:
Locations:
city: Columbus
country: United States
facility: Nationwide Children's Hospital
state: Ohio
Study officials:
affiliation: Nationwide Children's Hospital
name: Joseph Tobias
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00919087: Non Invasive Arrhythmia Detection in Hospital Settings
Official title: Evaluating Ventricular Events With Adherent Patient Monitoring Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Arrhythmias
Lead sponsor: Corventis, Inc.
Sponsor class: INDUSTRY
First posted: 2009-06-12
Enrollment: 25
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: electrophysiology (EP) study or implantable cardioverter defibrillator (ICD) implant Patients

Brief summary: This is a prospective, single center, non-randomized study to evaluate the arrhythmia detection performance during ventricular events.

Detailed description: The system will continuously monitor the patient's cardiac activity which will be compared to standard telemetry system.

Eligibility criteria: Inclusion Criteria:

* Is female or male, 18 years of age or older
* Undergoing ICD implant with ventricular arrhythmia induction OR undergoing EP study with ventricular arrhythmia induction

Exclusion Criteria:

* Is participating in another clinical study that may confound the results of this study

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Corventis, Inc.
name: Imad Libbus, PhD
role: STUDY_DIRECTOR
References:
Clinical trial NCT06004687: Effect of Acetaminophen Preemptive Analgesia on Postoperative Cognitive Function
Official title: Effects of Acetaminophen Preemptive Analgesia on Anesthesia Recovery Time and Postoperative Cognitive Function in Patients Undergoing Gastrointestinal Tumor Surgery
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE1
PHASE2
Conditions: Cognitive Function
Keywords: acetaminophen mannitol
cognitive function
anesthesia recovery time
gastrointestinal tumor surgery
Lead sponsor: Affiliated Hospital of Nantong University
Sponsor class: OTHER
First posted: 2023-08-22
Enrollment: 100
Sex: ALL
Minimum age (years): 16
Maximum age (years): 88
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Patients undergoing gastrointestinal tumor surgery are prone to delayed recovery and postoperative cognitive dysfunction due to greater trauma and longer operation time. Pre-analgesia can reverse the effects of nociceptive stimulation on recovery from general anesthesia and postoperative cognitive function. Intravenous injection of non-steroidal drugs can effectively reduce postoperative pain and the use of opioids. Therefore, This study selected acetaminophen mannitol injection for preemptive analgesia to observe the effects on anesthesia recovery time and postoperative cognitive function of patients undergoing gastrointestinal tumor surgery, providing new ideas for reducing cognitive dysfunction in patients undergoing gastrointestinal tumor surgery

Detailed description: By administering acetaminophen to patients with gastrointestinal tumors before surgery, recording the time to recovery from anesthesia, and assessing cognitive function status by CAM on the first, third, and seventh day after surgery

Eligibility criteria: Inclusion Criteria:

* Patients undergoing gastrointestinal tumor surgery
* American Society of Anesthesiologists（ASA）≤Ⅲ

Exclusion Criteria:

* History of severe adverse reactions to oral acetaminophen
* Dysfunction of heart, liver, kidney and other important organs
* History of chronic pain
* Oral non-steroidal or opioid drugs
* Patients who do not accept clinical trials

Primary outcomes:
measure: Postoperative delirium
timeFrame: 1/3/7 days after the surgery
Secondary outcomes:
measure: Recovery time
timeFrame: immediately after the surgery
Other outcomes:
measure: Neurotransmitters in the blood
timeFrame: 1/3/7 days after the surgery
Locations:
city: Nantong
country: China
facility: Affiliated Hospital of nantong University
state: Jiangsu
Study officials:
affiliation: Chair
name: Hongsheng Chen
role: STUDY_CHAIR
References:
Clinical trial NCT00371787: Evaluation of the Performance of Non-molded Soft Contact Lenses
Official title: Evaluation of the Performance of Non-molded Soft Contact Lenses
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Ametropia
Lead sponsor: University of Waterloo
Sponsor class: OTHER
Collaborators: name: CIBA VISION
First posted: 2006-09-04
Enrollment: 38
Sex: ALL
Minimum age (years): 17
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties.

Detailed description: To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties in a group of participants who present with lens related changes.

Eligibility criteria: Inclusion Criteria:

* Male or female, good health, age \>17yrs, able to wear contact lenses as primary vision correction, able to see well and achieve good fit with study lens, has understood \& signed consent form.

Exclusion Criteria:

* Has active ocular disease, uses topical eye medication, wears gas permeable/silicone hydrogel /overnight wear contact lenses, is a participant in another clinical study, is deemed unsuitable for soft contact lens wear.

Primary outcomes:
measure: Visual Acuity
timeFrame: baseline
measure: Visual Acuity
timeFrame: 9 month
measure: Neovascularisation
timeFrame: baseline
measure: Neovascularization
timeFrame: 9 month
Secondary outcomes:
Other outcomes:
Locations:
city: Waterloo
country: Canada
facility: Centre for Contact Lens Research, University of Waterloo,
state: Ontario
Study officials:
affiliation: Centre for Contact Lens Research
name: Desmond Fonn
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05331287: Comparing the "Snifing Position" , "Simple Head Extension" and "Neutral Position"
Official title: First Hospital of Qinhuangdao，Hebei Province, China
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Therapeutic Procedural Complication
Keywords: Snifing Position
Simple Head Extension
neutral position
Nasotracheal intubation
Lead sponsor: The First Hospital of Qinhuangdao
Sponsor class: OTHER_GOV
First posted: 2022-04-15
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: SEQUENTIAL
Primary purpose: OTHER

Brief summary: The simple head extension is recommended for optimization of glottic visualization during Nasotracheal intubation via fiberoptic bronchoscope (FOB) . However, no study confirmed its superiority over"snifing position" and "Neutral Position". In a prospective, randomized study, the authors compared the snifing position , simple head extension and "Neutral Position" in Nasotracheal intubation via fiberoptic bronchoscope.

Detailed description: The study included ninety patients with anticipated difficult airways. The snifing position was obtained by placement of a 7-cm cushion under the head of the patient; the extension head position was obtained by placement of a 7-cm cushion under the shoulder; the neutral position with the occiput close to the operating table. The head position was randomized as follows: neutral position group (NP group), sniffing position group (SP group) or extension position group (EP group). Randomization (1:1:1) was based on the codes generated by Excel software, which were kept in sequentially numbered opaque envelopes until the began of study.

Eligibility criteria: Inclusion Criteria:

• ASA classifications of I-II, modified Mallampati classification of 3 or 4, requiring general anesthesia were included.

Exclusion Criteria:

* • ASA class IV or V

  * Abnormalities of the heart, brain, liver, lung, kidney and coagulation functions

Primary outcomes:
measure: Intubation Time
timeFrame: Ten minutes
Secondary outcomes:
measure: Occurrence of throat pain measured by VAS
timeFrame: one day Postoperative]
Other outcomes:
Locations:
city: Qinhuangdao
country: China
facility: The first hospital of Qinhuangdao
state: Hebei
Study officials:
References: