Clinical trial NCT05809063: Characterization, Risk Factors and Outcome of Neonates Admitted to Neonatal Intensive Care Units (NICU) at Sohag University Hospitals
Official title: Characterization, Risk Factors and Outcome of Neonates Admitted to Neonatal Intensive Care Units (NICU) at Sohag University Hospitals
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Neonatal Diseases
Lead sponsor: Sohag University
Sponsor class: OTHER
First posted: 2023-04-12
Enrollment: 300
Sex: ALL
Minimum age (years): 1
Maximum age (years): 28
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: - All neonates that will be admitted in Neonatal Intensive Care Units (NICU) including preterm, term and post term neonates.

Brief summary: The neonatal period considered the time from birth up to the first 28 days of life \& further classified into:

* Very early birth (birth to \< 24 hours).
* Early birth (24 hours to \< 7 days).
* Late or last neonatal period (7 days to 28 days).

It is characterized by the transition from extra uterine life and rapid growth and development. It is the common vulnerable time or period of human life as it accounts for more high mortalities and morbidities, however, most of them are preventable.

The pattern of neonatal disease is a useful indicator of the availability, utilization and effectiveness of maternal and child health care services.

It varies from place to place and from time to time even in the same locality. Information on admission and mortality patterns of hospitalized neonates should reflect the major causes of illnesses and standard of care provided to neonates in a particular locality.

To improve neonatal services with better overall outcomes and less sever morbidities early identification of the risk factors is paramount so that appropriate interventions can be directed towards the most prevalent and treatable neonatal illnesses. To achieve this goal, it is important to study the pattern of neonatal admissions


Eligibility criteria: Inclusion Criteria:

* All neonates that will be admitted in Neonatal Intensive Care Units (NICU) including preterm, term and post term neonates.

Exclusion Criteria:

* Failure to obtain consent.
* Neonates need preparation for advanced interventions not available in our unit like cardiac operations.
* Neonates require peritoneal dialysis.
* Traumatic injury.

Primary outcomes:
measure: document the number, & outcome in neonates with respiratory diseases admitted to neonatal intensive care units
timeFrame: 12 months
measure: document the number, & outcome in neonates with cardiovascular diseases admitted to neonatal intensive care units
timeFrame: 12 months
measure: document the number, & outcome in neonates with gastrointestinal diseases admitted to neonatal intensive care units
timeFrame: 12 months
measure: document the number, & outcome in neonates with renal diseases admitted to neonatal intensive care units
timeFrame: 12 months
measure: document the number, & outcome in neonates with central nervous system diseases admitted to neonatal intensive care units
timeFrame: 12 months
measure: document the number, & outcome in neonates with metabolic diseases admitted to neonatal intensive care units
timeFrame: 12 months
measure: document the number, & outcome in neonates with endocrinal diseases admitted to neonatal intensive care units
timeFrame: 12 months
Secondary outcomes:
Other outcomes:
Locations:
city: Sohag
country: Egypt
facility: Sohag University hospitals
Study officials:
References:
citation: Persson M, Shah PS, Rusconi F, Reichman B, Modi N, Kusuda S, Lehtonen L, Hakansson S, Yang J, Isayama T, Beltempo M, Lee S, Norman M; International Network for Evaluating Outcomes of Neonates. Association of Maternal Diabetes With Neonatal Outcomes of Very Preterm and Very Low-Birth-Weight Infants: An International Cohort Study. JAMA Pediatr. 2018 Sep 1;172(9):867-875. doi: 10.1001/jamapediatrics.2018.1811.
citation: Mansoor KP, Ravikiran SR, Kulkarni V, Baliga K, Rao S, Bhat KG, Baliga BS, Kamath N. Modified Sick Neonatal Score (MSNS): A Novel Neonatal Disease Severity Scoring System for Resource-Limited Settings. Crit Care Res Pract. 2019 May 9;2019:9059073. doi: 10.1155/2019/9059073. eCollection 2019.
citation: Dorling JS, Field DJ, Manktelow B. Neonatal disease severity scoring systems. Arch Dis Child Fetal Neonatal Ed. 2005 Jan;90(1):F11-6. doi: 10.1136/adc.2003.048488.