Clinical trial NCT05720416: Effects of a Multi-intervention Programme for the Elderly
Official title: Effects of a Multi-intervention Programme on the Muscle Strength, Body Composition, Physical Performance and Quality of Life of the Elderly
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Sarcopenia
Sarcopenic Obesity
Dementia
Lead sponsor: Central Taiwan University of Science and Technology
Sponsor class: OTHER
First posted: 2023-02-09
Enrollment: 207
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: 1. To develop a multiactivity training programme. 2. To explore the effect of this programme on sarcopenia, sarcopenic obesity, cognitive impairment and Parkinson's disease. 3. To compare the effects of the experimental and control treatments on the muscle strength, body composition, physical function performance and quality of life of the elderly.


Eligibility criteria: Inclusion Criteria:

(1) over 60 years old, (2) able to Communicate and follow instructions; (3) Stable condition with sufficient physical strength: able to maintain a seated position in a wheelchair or on the edge of a bed for at least one hour. (4) sarcopenia, sarcopenic obesity, cognitive impairment and Parkinson's disease.

Exclusion Criteria:

(1) difficulty in standing or walking and obvious musculoskeletal disease, (2) unsuitable for diagnosis by a physician those engaged in sports activities, (3) serious diseases/unstable states, such as severe heart, lung, liver and kidney diseases, severe malignant tumors, severe nutrition poor, severe dementia, (4) more than 180 minutes of exercise per week in the past month, (5) no willingness to participate.

Primary outcomes:
measure: Chang in muscle strength from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in weight of muscle and fat from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in Activities of Daily Living from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in Instrumental activities of daily living from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in Clinical Dementia Rating from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in Cornell Scale for Depression in Dementia from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in Cohen-Mansfield Agitation Inventory from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in EQ5D from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in QUALIDEM from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Demographic attributes
timeFrame: Baseline
measure: Chang in PERSONAL WELLBEING INDEX from baseline to 16 weeks
timeFrame: Baseline and 16 weeks
measure: Chang in PERSONAL WELLBEING INDEX intellectual disability from baseline to 16 weeks
timeFrame: Baseline and 16 weeks.
measure: Chang in World Health Organization Quality of Life Instruments (WHOQOL-BREF) from baseline to 16 weeks
timeFrame: Baseline and 16 weeks.
measure: Chang in Four-Meter Gait Speed from baseline to 16 weeks
timeFrame: Baseline and 16 weeks.
Secondary outcomes:
Other outcomes:
Locations:
city: Taichung
country: Taiwan
facility: Daycare center at Central Taiwan University of Science and Technology
Study officials:
affiliation: Central Taiwan University of Science and Technology
name: Chiu
role: PRINCIPAL_INVESTIGATOR
References: