Clinical trial NCT02946086: Effect of HABIT-ILE on Visuo-spatial Attention of Children With Unilateral CP
Official title: Effect of Rehabilitation in Deficiencies, Activities Limitations and Restrictions of the Participation of the Children Presenting Neurological Lesions. Impact of Contextual Factors on the Functioning of These Patients. Part II
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cerebral Palsy
Keywords: motor skill learning, visuo-spatial attention
Lead sponsor: Université Catholique de Louvain
Sponsor class: OTHER
First posted: 2016-10-26
Enrollment: 35
Sex: ALL
Minimum age (years): 5
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study aims to investigate the changes induced by HABIT-ILE in impairments, activity and participation of children with unilateral CP, as well as neuroplastic changes induced by the treatment. Visuospatial deficits will be investigated and the effect of prismatic adaptation will be measured.

Detailed description: This study aims to investigate the changes induced by HABIT-ILE at the 3 levels of the international classification of functioning and health (ICF) in children with unilateral CP, as well as neuroplastic changes induced by the treatment. Visuospatial deficits will be investigated and the effect of prismatic adaptation will be measured.

Eligibility criteria: Inclusion Criteria:

* unilateral CP
* minimal ability to pick an light object from a table
* age 5-18

Exclusion Criteria:

* no active seizure
* no botox or orthopedic intervention in the 6 months preceding the study or during the study

Primary outcomes:
measure: changes in star cancellation
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: change in "Ogden Figure" test
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: changes in line bissection
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: visuo-spatial pointing
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: proprioceptive pointing
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
Secondary outcomes:
measure: Jebsen-Taylor test of hand function
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: functional magnetic resonance imaging (fMRI)
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: Box and blocks
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: Assisting Hand Assessment
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: "ABILHAND-Kids" questionnaire
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: "ACTIVLIM-CP" questionnaire
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: Canadian Occupationnal Performance Measure
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
measure: diffusion tensor imaging (DDTI)
timeFrame: at baseline and after 90 hours/two weeks of intensive bimanual intervention
Other outcomes:
Locations:
city: Brussels
country: Belgium
facility: Bleyenheuft Yannick
Study officials:
affiliation: Institute of Neuroscience, Université catholique de Louvain
name: Yannick Bleyenheuft, PhD
role: PRINCIPAL_INVESTIGATOR
References: