Clinical trial NCT03300895: High-intensity Interval Training on Cardiorespiratory Fitness in Overweight Women
Official title: Effect of Low-volume High-intensity Interval Training on Cardiorespiratory Fitness and Total Body Fat in Overweight Women
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy Volunteers
Lead sponsor: Universidad de Antioquia
Sponsor class: OTHER
First posted: 2017-10-04
Enrollment: 35
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 44
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: High-intensity interval training (HIIT) is currently considered one of the most effective strategies to improved cardiorespiratory fitness, which is recognized as a protective factor for cardiovascular diseases and metabolic diseases such as overweight and obesity. However, current evidence is still limited and requires clarity (frequency, time per session and intensity) regarding to greater increases attributed to HIIT.

The aim of this study is to compare the effect of a low-volume high-intensity interval training versus a moderate-intensity continuous exercise on maximal oxygen consumption in overweight women 18 to 44 years old.

Detailed description: Thirty-six women will be randomly assigned to one of two aerobic exercise on a real-life setting supervised for a physical activity instructor. The interventions will performed three times a week for ten-weeks (on alternate days).

The first two weeks will correspond to the conditioning period (30 minutes between 55-65% of maximum heart rate (HRmax). From week three, 18 participants will perform 30 minutes of continuous exercise at an intensity between 65-75 % of HRmax, and the remaining 18 will complete 21.5 minutes of interval exercise at an intensity between 90-95% of HRmax, with recoveries between 50-55% of HRmax.

All Participants will be evaluated to measure their maximal oxygen consumption, total body fat, waist circumference, body mass index, systolic blood pressure, diastolic blood pressure, prior to start the interventions and at the end of the program (week 11).

Eligibility criteria: Inclusion Criteria:

* Overweight (≥ 25 kg/m-2) women 18 to 44 years.
* Healthy volunteers.
* Perform ≤ 600 Met/min/week.

Exclusion Criteria:

* Perform high-intensity interval exercise in the last six month.
* Smoker.
* History of asthma.
* History of diabetes.
* History of hypertension.
* History of cardiovascular disease.
* History of coronary heart disease.
* Arrhythmias.
* Personal history of surgical procedures in the last three months
* Uncontrolled non-communicable diseases
* Under medical treatment with anticoagulants, beta-blockers, calcium antagonists, bronchodilators, and/or steroids.
* Psychological, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.
* Psychoactive drug abuse.

Primary outcomes:
measure: Change in maximal oxygen consumption
timeFrame: Baseline and after 10 weeks
Secondary outcomes:
measure: Change in total body fat
timeFrame: Baseline and after 10 weeks
Other outcomes:
Locations:
city: Medellín
country: Colombia
facility: Universidad de Antioquia
state: Antioquia
Study officials:
References:
citation: Arboleda-Serna VH, Patino-Villada FA, Pinzon-Castro DA, Arango-Velez EF. Effects of low-volume, high-intensity interval training on maximal oxygen consumption, body fat percentage and health-related quality of life in women with overweight: A randomized controlled trial. J Exerc Sci Fit. 2022 Apr;20(2):108-112. doi: 10.1016/j.jesf.2022.01.004. Epub 2022 Feb 4.