Clinical trial NCT04119310: Lumbar Thrust-mobilization Effects on Hip Strength and Anterior Knee Pain
Official title: Lumbar Thrust-mobilization Effects on Hip Strength and Anterior Knee Pain, a Double Blind Randomized Control Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Anterior Knee Pain Syndrome
Lead sponsor: Messiah College
Sponsor class: OTHER
First posted: 2019-10-08
Enrollment: 128
Sex: ALL
Minimum age (years): 18
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Participants will be randomly assigned to one of two interventions, thrust-mobilization or sham mobilization.
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to investigate changes in lateral hip muscle strength as well as self-reported pain during the performance of three functional tests in patients with anterior knee pain following a lumbopelvic thrust-mobilization.

Hypothesis(es):

Lumbar thrust-mobilization will lead to increased lateral hip strength and decreased anterior knee pain during 3 functional activities (single leg step down, functional squat, drop jump).

Detailed description: The participant will complete a medical history form and undergo a brief physical exam of the lumbar spine and knees to include: lumbar range of motion and mobility testing, knee range of motion, palpation, and knee mobility testing. The participant will complete a hip strength test utilizing the Biodex System 4 Pro®. The participant will then perform three activities (single leg step down, squat, and drop jump from a 2 foot platform) and provide a self-reported knee pain measure with each activity. A sealed envelope indicating the intervention to be received will be given to the participant. An investigator blinded to the pre and post-measures will open the envelope indicating the intervention to be performed. The participant will be blinded to which intervention group they are categorized to. Th e participant will be positioned on a high-low treatment table to receive the assigned intervention. The participant will be positioned to receive either intervention 1 (thrust mobilization) or 2 (sham mobilization). The participant will either receive the thrust-mobilization or sham mobilization up to 2 times on the left and right side. An immediate re-test of hip strength will be conducted followed by performing the same three functional activities (single leg step down, squat, and drop jump from a 2 foot platform) while providing a self-reported pain measure after each activity. Follow-up measures at 15 minutes post-intervention and the final measure at 30 minutes post-intervention will be performed.

Eligibility criteria: Inclusion Criteria:

* Healthy males and females between the ages of 18 and 25 with non-traumatic anterior knee pain
* Able read and write in English
* Clearly understand the informed consent form

Exclusion Criteria:

* Low back pain
* Pregnant or may be pregnant
* Previously diagnosed with spondylolisthesis,
* Previously diagnosed with a herniated disc,
* Signs and symptoms of nerve root compression
* History of spine surgery
* History of knee surgery
* History of cancer
* History of compression fracture
* History of osteoporosis
* History of osteopenia
* History of a systemic disease
* History of a connective tissue disease
* History of a neurological disease
* Pain with pre-manipulative hold
* Positive findings on medical history form, or physical exam
* Presence of anxiety during the procedure

Primary outcomes:
measure: Change in lateral hip strength
timeFrame: Pre-intervention, immediately following intervention, 15 min post-intervention & 30 min post-intervention
measure: Change in pain with single leg step down
timeFrame: Pre-intervention, immediately following intervention, 15 min post-intervention & 30 min post-intervention
measure: Change in pain with double leg squat
timeFrame: Pre-intervention, immediately following intervention, 15 min post-intervention & 30 min post-intervention
measure: Change in pain with drop jump from 2 foot platform
timeFrame: Pre-intervention, immediately following intervention, 15 min post-intervention & 30 min post-intervention
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
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