Clinical trial NCT05685381: Indoor Air Quality for Black Adults With Uncontrolled Asthma
Official title: Contextualizing Asthma Self-Management With Measures of Indoor Air Quality for Black Adults With Uncontrolled Asthma
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Asthma
Keywords: Asthma
Bronchial Diseases
Respiratory Tract Diseases
Lung Diseases, Obstructive
Lung Diseases
Respiratory Hypersensitivity
Hypersensitivity, Immediate
Hypersensitivity
Immune System Diseases
Greenhouse Effect
Air Pollution, Indoor
Lead sponsor: Columbia University
Sponsor class: OTHER
Collaborators: name: National Institute of Nursing Research (NINR)
First posted: 2023-01-17
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Black adults with persistent asthma that receive care at partner federally qualified health centers

Brief summary: The aims of this project are twofold:

1. to characterize indoor air quality components obtained from apartments with gas stoves and open kitchens in a cohort of Black adults with uncontrolled asthma recruited from federally qualified health centers and enrolled in the parent study.
2. to conduct a comprehensive assessment of feasibility, implementation, and acceptability of the study.

Detailed description: People spend as much as 90% of their time indoors, making indoor air quality (IAQ) particularly important to health. Many homes in New York City, particularly low-income housing, contain gas kitchen appliances, which generate fuel through the combustion of natural gas, generating indoor pollutants. Increasing evidence finds that even low levels of these pollutants are hazardous for human health. Those most vulnerable to ambient air pollution live in homes with gas appliances and inadequate ventilation. Moreover, individuals with pre-existing diseases like asthma are particularly susceptible to adverse health effects from poor IAQ, which gas stoves may exacerbate. This study addresses the important problem of uncontrolled asthma among a group at high risk for asthma and its adverse effects - Black adults who reside in homes with gas stoves and open kitchens. The investigator aims to characterize indoor air quality components in a cohort enrolled in the parent R01 (NCT05341726) and conduct a comprehensive assessment of feasibility including process, implementation and acceptability metrics. Identifying new targets for asthma self-management that could produce better health outcomes, thus addressing an important health inequity issue.

Eligibility criteria: Inclusion Criteria (participants):

Patient participants will

1. be adults (\> or = 18 years of age)
2. self-report race as 'Black' race (African American, African, Caribbean, West Indian, multi-racial \[Black AND one or more additional races\]); identify their ethnicity as Hispanic OR non-Hispanic
3. have clinician-diagnosed persistent asthma (defined as being prescribed inhaled corticosteroids in the last 48 months) or have had an asthma exacerbation (e.g., ER visit, course of Prednisone) regardless of controller medicine use
4. receive asthma care at a partner federally qualified health center and
5. screen positive for uncontrolled asthma as measured by the Asthma Control Questionnaire- 6 items (ACQ-6) and erroneous beliefs as measured by the Conventional and Alternative Management for Asthma (CAM-A) survey.

Exclusion Criteria (participants):

1. non-English speaking or
2. serious mental health conditions that preclude completion of study procedures or confound analyses

Primary outcomes:
measure: Completion of acceptability questionnaire
timeFrame: Post-trial visit (up to 3 months after intervention completion)
Secondary outcomes:
Other outcomes:
Locations:
city: Beacon
country: United States
facility: Sun River Health
state: New York
city: Brooklyn
country: United States
facility: Bedford Stuyvesant Family Health Center
state: New York
Study officials:
affiliation: Columbia University School of Nursing
name: Maureen George, PhD
role: PRINCIPAL_INVESTIGATOR
References: