Clinical trial NCT06002776: Our Anesthesia Experiences in Hepatopancreatobiliary Surgery Practices: a Retrospective Study
Official title: Our Anesthesia Experiences in Hepatopancreatobiliary Surgery Practices: a Retrospective Study
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Experience, Life
Keywords: major abdominal surgery
Revised Cardiac Risk Index
Epidural analgesia
perioperative fluid management
ERAS protocols
Lead sponsor: Sisli Hamidiye Etfal Training and Research Hospital
Sponsor class: OTHER
First posted: 2023-08-21
Enrollment: 6
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: data from all patients aged 18 and above who underwent major abdominal surgery with diagnoses of liver malignancy, cholangiocarcinoma, and pancreatic malignancy

Brief summary: Has the evolving anesthetic management in major abdominal surgeries had a positive impact on patients' one-year postoperative mortality and length of hospital stay? Which of the anesthetic management parameters have influenced mortality and hospital stay duration in these patients? To address these questions, we have planned to retrospectively review patients who underwent surgery at our center.

Detailed description: In our study, we aimed to compile our practices over the last 5 years by evaluating the impact of perioperative and postoperative anesthetic management on morbidity and mortality in hepatopancreatobiliary surgical patients. Our primary outcome was to form a comprehensive understanding of our anesthesia experiences during the preoperative, perioperative, and postoperative periods in this patient group. Our secondary outcome was to assess the influence of preoperative and perioperative anesthetic management on the morbidity and mortality of these patients.

Eligibility criteria: Inclusion Criteria:

* The study will include data from patients who have undergone their first operation with the diagnoses of liver malignancy, cholangiocarcinoma, and pancreatic malignancy during the period from October 2017 to February 2022.

Exclusion Criteria:

* Data from patients who were deemed inoperable during the perioperative period after being taken into surgery with their current diagnosis, as well as data from patients who underwent repeat operations, were excluded from the study for their second and subsequent hospitalizations.

Primary outcomes:
measure: form a comprehensive understanding of our anesthesia experiences during the preoperative, perioperative, and postoperative periods in this patient group
timeFrame: october2017-february2022
Secondary outcomes:
measure: assess the influence of preoperative and perioperative anesthetic management on the morbidity and mortality of these patients.
timeFrame: october2017-february2022
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Sisli Hamidiye Etfal Training and Researching Hospital
state: Sarıyer
Study officials:
References:
citation: Snowden C, Prentis J. Anesthesia for hepatobiliary surgery. Anesthesiol Clin. 2015 Mar;33(1):125-41. doi: 10.1016/j.anclin.2014.11.008. Epub 2014 Dec 31.
citation: Hemmerling TM. Pain management in abdominal surgery. Langenbecks Arch Surg. 2018 Nov;403(7):791-803. doi: 10.1007/s00423-018-1705-y. Epub 2018 Oct 3.
citation: von der Forst M, Weiterer S, Dietrich M, Loos M, Lichtenstern C, Weigand MA, Siegler BH. [Perioperative fluid management in major abdominal surgery]. Anaesthesist. 2021 Feb;70(2):127-143. doi: 10.1007/s00101-020-00867-7. German.