Clinical trial NCT05348031: Multimodal Analysis of Structural Voice Disorders Based on Speech and Stroboscopic Laryngoscope Video
Official title: Multimodal Analysis of Structural Voice Disorders Based on Speech and Stroboscopic Laryngoscope Video
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Voice Disorders
Keywords: deep learning
multimodality
structural voice disorders
stroboscopic laryngoscope video
Speech
Lead sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sponsor class: OTHER
Collaborators: name: Duke Kunshan University
First posted: 2022-04-27
Enrollment: 1
Sex: ALL
Minimum age (years): 20
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: In this study, 490 patients with voice disorders (including laryngeal cancer, laryngeal precancerous lesions, and benign laryngeal lesions) and 50 healthy people were collected from stroboscopic laryngoscopy videos and vowel audio recordings. Gender, course of disease, VHI and other clinical data.

Brief summary: This study intends to collect clinical data such as strobary laryngoscope images and vowel audio data of patients with structural voice disorders and healthy individuals, and to establish a multimodal voice disorder diagnosis system model by using deep learning algorithms. Multi-classification of diseases that cause voice disorders can be applied to patients with voice disorders but undiagnosed in clinical practice, thereby assisting clinicians in diagnosing diseases and reducing misdiagnosis and missed diagnosis. In addition, some patients with voice disorders can be managed remotely through the audio diagnosis model, and better follow-up and treatment suggestions can be given to them. Remote voice therapy can alleviate the current situation of the shortage of speech therapists in remote areas of our country, and increase the number of patients who need voice therapy. opportunity. Remote voice therapy is more cost-effective, more flexible in time, and more cost-effective.

Detailed description: 1. Detection and Classification of Acoustic Lesions Based on Speech Deep Learning
2. Detection and Classification of Acoustic Lesions Based on Deep Learning of Images
3. Detection and Classification of Acoustic Lesions Based on Deep Learning Based on Multimodality

Eligibility criteria: Inclusion Criteria:

Laryngeal cancer, laryngeal precancerous lesions, benign laryngeal lesions with voice disorders, healthy people without throat diseases

Exclusion Criteria:

1. A history of laryngeal surgery
2. Patients with voice disorders caused by various causes except laryngeal cancer, laryngeal precancerous lesions, and benign laryngeal lesions
3. The audio quality is not clear, the stroboscopic laryngoscope does not clearly display the anatomical area related to the glottis, and it is underexposed and blocked;

Primary outcomes:
measure: Machine deep learning classifies vocie disorders
timeFrame: May 6,2022-December 30,2023
measure: Machine deep learning classifies vocie disorders witn multimodality
timeFrame: January 1,2024-December 30,2024
measure: Machine deep learning classifies pathological voice change in Laryngeal Cancer
timeFrame: January 1,2024-December 30,2025
Secondary outcomes:
measure: Machine deep learning classifies vocie disorders witn multimodality
timeFrame: January 1,2024-December 30,2025
Other outcomes:
Locations:
Study officials:
affiliation: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
name: YueXin Cai
role: STUDY_CHAIR
References:
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