Clinical trial NCT03409172: Inflammatory and Metabolic Outcomes After Obese Woman Performed High Intensity Interval Training
Official title: Inflammatory and Metabolic Outcomes in Obese Women After 8 Weeks of High Intensity Interval Training and Moderate Intensity Continuous Training: a Randomized Controlled Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Obesity and Metabolic Syndrome
Keywords: High intensity interval training
Inflammation
Obesity
adipokines
Lead sponsor: University of Sao Paulo
Sponsor class: OTHER
First posted: 2018-01-24
Enrollment: 48
Sex: FEMALE
Minimum age (years): 25
Maximum age (years): 41
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Three-arm parallel, Randomized-controlled study
Primary purpose: TREATMENT

Brief summary: The main purpose of this study is to compare the effects of high intensity interval training and moderate intensity continuous training on inflammatory profile and metabolic markers, after 8 weeks of intervention trial in obese women.


Eligibility criteria: Inclusion Criteria:

* Body Mass Index between (30-40 kg/m²)
* age between 25 and 41 years
* to be sedentary

Exclusion Criteria:

* type 1 or type 2 diabetes
* Hypertension
* pregnancy, Lactation
* having undergone bariatric surgery
* psychological disorders, epilepsy, sever neurological disorders
* participation in other moderate, vigorous exercise or nutrition intervention
* acute or chronic cardiovascular disease
* malignant disease
* kidney disease
* lung disease
* hyperthyroidism or hypothyroidism
* smoking any type of cigarette
* joint limitations
* electronic implants (defibrillator, pacemaker)

Primary outcomes:
measure: Inflammatory profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment)
measure: Inflammatory profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment)
measure: Inflammatory profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment)
Secondary outcomes:
measure: Body Composition and Anthropometric profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Body Composition and Anthropometric profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Body Composition and Anthropometric profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Body Composition and Anthropometric profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Insulin sensitivity
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Lipid profile
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Cardiorespiratory Fitness (CRF)
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Blood Pressure (BP)
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Resting Energy Expenditure (REE)
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
measure: Substrate oxidation rate
timeFrame: 8 weeks (baseline to 8 week follow-up assessment) ]
Other outcomes:
Locations:
Study officials:
affiliation: fmrp usp
name: Vivian M M SUEN, PhD
role: STUDY_DIRECTOR
References: