Clinical trial NCT06269731: Anxiety & Depression in Thyroid Cancer Patients
Official title: Anxiety, Depression and Quality of Life in Thyroid Cancer Patients
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Thyroid Cancer
Keywords: depression
anxiety
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2024-02-21
Enrollment: 159
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: thyroid cancer patients

Brief summary: 1. To identify the prevalence of both anxiety and depression in thyroid cancer patients
2. To assess quality of life in thyroid cancer patients

Detailed description: In recent years, increasing attention has been paid to mental health among cancer patients.

Thyroid cancer is one of the most frequent endocrine neoplasia. It consists of 4 subtypes of papillary thyroid cancer, follicular thyroid cancer, medullary thyroid cancer, and anaplastic thyroid cancer.

Which is usually asymptomatic in the early stages, but symptoms such as neck pain, hoarseness, and dysphagia may occur as the disease progresses. TC is diagnosed by physical examination, analysis of thyroid hormone levels, imaging, and biopsy.

Anxiety and depression are the most common psychological problems in the treatment of cancer patients and are related to the majority of medical diseases and physical symptoms.

Studies have suggested that anxiety and depression are common in patients with thyroid cancer.

Therefore, quality of life which includes psychological, social, and spiritual well-being, has become an important consideration .

These findings highlight the importance of identifying thyroid cancer patients needs to allow better and more adequate care and support.

Eligibility criteria: Inclusion Criteria:

1. Age at or more than 18 years old
2. None of the patients had history of other psychiatric illness
3. Both sex
4. Accept to participate in the study

Exclusion Criteria:

1. Age less than 18 years old
2. Previous history of other psychiatric illness
3. substance abuser or dependence
4. Refuse to participate in the study

Primary outcomes:
measure: the prevalence of anxiety in thyroid cancer patients
timeFrame: baseline
measure: the prevalence of depression in thyroid cancer patients
timeFrame: baseline
Secondary outcomes:
measure: assess quality of life in thyroid cancer patients
timeFrame: baseline
Other outcomes:
Locations:
Study officials:
References:
citation: Tagay S, Herpertz S, Langkafel M, Erim Y, Bockisch A, Senf W, Gorges R. Health-related Quality of Life, depression and anxiety in thyroid cancer patients. Qual Life Res. 2006 May;15(4):695-703. doi: 10.1007/s11136-005-3689-7.
citation: Dionisi-Vici M, Fantoni M, Botto R, Nervo A, Felicetti F, Rossetto R, Gallo M, Arvat E, Torta R, Leombruni P. Distress, anxiety, depression and unmet needs in thyroid cancer survivors: a longitudinal study. Endocrine. 2021 Dec;74(3):603-610. doi: 10.1007/s12020-021-02786-y. Epub 2021 Jun 18.
citation: Alexander K, Lee SC, Georgiades S, Constantinou C. The "not so good" thyroid cancer: a scoping review on risk factors associated with anxiety, depression and quality of life. J Med Life. 2023 Mar;16(3):348-371. doi: 10.25122/jml-2022-0204.