Clinical trial NCT06909994: Daily Living Activities in Young Adults With Cerebral Palsy
Official title: Sensory Function and Its Relationship With Motor Performance and Daily Living Activities in Young Adults With Cerebral Palsy
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cerebral Palsy
Sensitivity
Motor Skills Disorders
Activity, Motor
Lead sponsor: Universidad de Burgos
Sponsor class: OTHER
First posted: 2025-04-04
Enrollment: 36
Sex: ALL
Minimum age (years): 16
Maximum age (years): 45
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: A multicenter cross-sectional study was conducted involving two groups of 36 participants aged 16-45 years.

Brief summary: This study explored the relationship between sensory function and occupational performance in young adults with Cerebral Palsy. Using standardized assessments, researchers compared tactile sensitivity and discrimination between individuals with CP and neurotypical controls, and examined how these sensory variables relate to motor function, ADLs, and IADLs.

Detailed description: Background: Sensory impairments are increasingly recognized as influential factors in the occupational performance of individuals with Cerebral Palsy (CP). Although prior studies have explored this relationship in children, evidence in young adults remains limited.

Objective: This study aimed to compare tactile sensitivity and discrimination in young adults with CP and neurotypical individuals, and to examine their association with motor-related variables relevant to occupational performance: muscle tone, grip strength, manual dexterity, Activities of Daily Living (ADLs), and Instrumental Activities of Daily Living (IADLs).

Methods: A multicenter cross-sectional study was conducted involving two groups of 36 participants aged 16-45 years. Sensory and motor variables were assessed using the Semmes-Weinstein Monofilaments, Two-Point Discrimination Test, Modified Ashworth Scale, Digital Dynamometer, Box and Block Test, Functional Independence Measure, and the Lawton and Brody Scale.

Conclusion: Findings highlight the relevance of sensory function in the occupational performance of young adults with CP. These results underscore the need for occupational therapy interventions that integrate sensory assessments and target sensory-motor integration to improve functional independence and participation.

Eligibility criteria: Inclusion Criteria:

* young people and adults with a medical diagnosis of CP, who had a motor condition of hemiparesis, diparesis, or tetraparesis;
* aged between 16 and 45 years
* had a minimum score of 19 on the Mini Mental State Examination cognitive assessment scale
* authorized their participation in the study by signing an informed consent form. In cases between the ages of 16 and 18 years, informed consent was signed by the participants and their parents or legal guardians

Exclusion Criteria:

* any peripheral nerve injury
* shoulder, elbow, wrist or hand injuries
* individuals whose mother tongue was neither Portuguese nor Spanish

Primary outcomes:
measure: Semmes-Weinstein monofilaments
timeFrame: 1 month
measure: Two-point discrimination test
timeFrame: 1 month
measure: Modified Ashworth Scale (MAS)
timeFrame: 1 month
measure: Digital dynamometer
timeFrame: 1 month
measure: Box and Block Test
timeFrame: 1 month
measure: Functional Independence Measure
timeFrame: 1 month
measure: Lawton and Brody Scale
timeFrame: 1 month
Secondary outcomes:
Other outcomes:
Locations:
city: Burgos
country: Spain
facility: Olalla Saiz Vazquez
Study officials:
References:
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citation: Bleyenheuft Y, Gordon AM. Precision grip control, sensory impairments and their interactions in children with hemiplegic cerebral palsy: a systematic review. Res Dev Disabil. 2013 Sep;34(9):3014-28. doi: 10.1016/j.ridd.2013.05.047. Epub 2013 Jun 29.