Clinical trial NCT05477238: Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls
Official title: Oxygen Consumption in Post-stroke Patients During Various Walking Activities Compared to Healthy Controls
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cerebrovascular Accident
Keywords: Stroke
Oxygen consumption
physical activity
Lead sponsor: University Hospital, Limoges
Sponsor class: OTHER
First posted: 2022-07-28
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Monocentric, cross-sectional and comparative study
Primary purpose: BASIC_SCIENCE

Brief summary: Stroke is major public health issue. The investigators recommend post-stroke patients to practice physical activity. Nevertheless, the recommendations are not widely respected due to the intensity of exercises. Oxygen consumption is a parameter to assess the intensity of physical activity. in this sense, we want to measure the oxygen consumption during various walking tasks compared to healthy controls.

Detailed description: Stroke is defined as an interruption of blood circulation in the brain. The treatments are in first time medical in emergency. Then, the patient will start his rehabilitation with several contributors. At this time, it will recommend physical activity to patients. Regardless of the all benefits of physical activity, it will help patient to avoid a second stroke. The investigators have the recommendations of the high authority of health in physical activity for stroke population. It recommends to practice around 20 to 60 minutes daily of physical activity with moderate effort intensity. Oxygen consumption is a parameter of effort intensity of physical activity measured in ml O2/kg/min. Currently, the investigators have the compendium of physical activity (PA). it allows us to classify PA according to effort intensity. And so, an activity with a moderate effort intensity is an activity between 3 and 5.9 metabolic equivalent task (MET). Note that 1 MET is 3.5 ml/O2/Kg. Nevertheless, this compendium does not correspond to post-stroke individuals. As consequences, Low intensity exercise as described in guidelines might be at a moderate intensity level for stroke survivors. Hence, the investigators want to assess the oxygen consumption of post-stroke individuals during various walking tasks and compare it to healthy controls.

Eligibility criteria: Inclusion Criteria:

Common to both groups:

* Age \>=18 years
* Able to give consent
* Not under guardianship or curatorship
* Enrolled in the French social security system

Specific to the cerebrovascular accident Group:

* Stroke confirmed by brain imaging
* Able to walk stairs without human assistance (modified Functional Ambulation Classification \>= 6)

Healthy Group Specific:

- Individuals matched to stroke individuals on age sex and BMI.

Exclusion Criteria:

Cerebrovascular accident group - Severe cognitive impairment (MoCA \< 18)

Common to both groups:

- Presence of contraindication to physical activity: unstable diabetes, unstable hypertension, unstable angina, intra-cardiac thrombus.

Primary outcomes:
measure: Oxygen consumption measurement
timeFrame: Day 1
measure: Oxygen consumption measurement
timeFrame: Day 7
Secondary outcomes:
measure: Walking speed measurement
timeFrame: Day 1
measure: Walking speed measurement
timeFrame: Day 7
measure: Cardiac frequency measurement
timeFrame: Day 1
measure: Cardiac frequency measurement
timeFrame: Day 7
measure: Perception of effort
timeFrame: Day 1
measure: Perception of effort
timeFrame: Day 7
measure: Total energy expenditure
timeFrame: Day 1
measure: Total energy expenditure
timeFrame: Day 7
Other outcomes:
Locations:
city: Limoges
country: France
facility: Limoges university hospital
Study officials:
References: