Clinical trial NCT00539214: Non-interventional Observational Study With Pramipexole: Impact on Non-motor Symptoms in Parkinson's Disease
Official title: Non-motor Symptoms (Depressive Symptoms) of Parkinson's Disease and Their Course Under Pramipexole Treatment
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Parkinson Disease
Lead sponsor: Boehringer Ingelheim
Sponsor class: INDUSTRY
First posted: 2007-10-04
Enrollment: 1192
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: PD patients

Brief summary: * To compare the effect of pramipexole on depressive symptoms in early and advanced PD patients
* To evaluate the course of depressive symptoms measured with UPDRS Part I (mentation, behavior and mood) and with HADS-D under pramipexole treatment
* To investigate whether improvement of depressive symptoms is linked to improvement in motor function (UPDRS Part III)

Detailed description: Study Design:

Eligibility criteria: Inclusion criteria:

1. Idiopathic Parkinsons disease with or without fluctuations
2. Indication for treatment with Sifrol®
3. Male or female patients of age
4. Presence of at least mild depressive symptoms (as judged by the treating physician)
5. Ability to reliably complete a self-rating scale (HADS)

Exclusion criteria:

1. Any contraindications according to the Summary of Product Characteristics (SPC): hypersensitivity to pramipexole or to any of the excipients.
2. Ongoing treatment with Sifrol®.

Primary outcomes:
measure: Improvement of depressive symptoms (UPDRS item 3, HADS-D) compared to baseline in early and advanced Parkinsons's disease
timeFrame: 9-16 weeks
measure: Change in sum scores of UPDRS Part III (motor examination) from baseline and UPDRS Part I (mentation, behavior and mood) from baseline
timeFrame: 9-16 weeks
measure: Change in HADS subscores (anxiety and depression) from baseline
timeFrame: 9-16 weeks
Secondary outcomes:
measure: Baseline pattern of patient rated symptom list (HADS)
timeFrame: 9-16 weeks
measure: Correlation of the change in UPDRS Part I and UPDRS Part III at the final visit
timeFrame: 9-16 weeks
measure: Frequency of adverse events
timeFrame: 9-16 weeks
Other outcomes:
Locations:
city: Aalen
country: Germany
facility: Boehringer Ingelheim
city: Aarbergen
country: Germany
facility: Boehringer Ingelheim
city: Adendorf
country: Germany
facility: Boehringer Ingelheim
city: Aham
country: Germany
facility: Boehringer Ingelheim
city: Ahaus
country: Germany
facility: Boehringer Ingelheim
city: Ahlen
country: Germany
facility: Boehringer Ingelheim
city: Ahorntal
country: Germany
facility: Boehringer Ingelheim
city: Aichach
country: Germany
facility: Boehringer Ingelheim
city: Aislingen
country: Germany
facility: Boehringer Ingelheim
city: Albstadt
country: Germany
facility: Boehringer Ingelheim
city: Aldenhoven
country: Germany
facility: Boehringer Ingelheim
city: Aldingen
country: Germany
facility: Boehringer Ingelheim
city: Alfeld
country: Germany
facility: Boehringer Ingelheim
city: Alpirsbach
country: Germany
facility: Boehringer Ingelheim
city: Alsdorf
country: Germany
facility: Boehringer Ingelheim
city: Altena
country: Germany
facility: Boehringer Ingelheim
city: Altenstadt
country: Germany
facility: Boehringer Ingelheim
city: Altomünster
country: Germany
facility: Boehringer Ingelheim
city: Alveslohe
country: Germany
facility: Boehringer Ingelheim
city: Amberg
country: Germany
facility: Boehringer Ingelheim
city: Ammerbuch
country: Germany
facility: Boehringer Ingelheim
city: Andernach
country: Germany
facility: Boehringer Ingelheim
city: Anklam
country: Germany
facility: Boehringer Ingelheim
city: Apolda
country: Germany
facility: Boehringer Ingelheim
city: Armsheim
country: Germany
facility: Boehringer Ingelheim
city: Arzberg
country: Germany
facility: Boehringer Ingelheim
city: Aschaffenburg
country: Germany
facility: Boehringer Ingelheim
city: Aschersleben
country: Germany
facility: Boehringer Ingelheim
city: Aschheim
country: Germany
facility: Boehringer Ingelheim
city: Attendorn
country: Germany
facility: Boehringer Ingelheim
city: Auerbach
country: Germany
facility: Boehringer Ingelheim
city: Augsburg
country: Germany
facility: Boehringer Ingelheim
city: Aurich
country: Germany
facility: Boehringer Ingelheim
city: Babensham
country: Germany
facility: Boehringer Ingelheim
city: Backnang
country: Germany
facility: Boehringer Ingelheim
city: Bad Arolsen
country: Germany
facility: Boehringer Ingelheim
city: Bad Berleburg
country: Germany
facility: Boehringer Ingelheim
city: Bad Bevensen
country: Germany
facility: Boehringer Ingelheim
city: Bad Düben
country: Germany
facility: Boehringer Ingelheim
city: Bad Dürrenberg
country: Germany
facility: Boehringer Ingelheim
city: Bad Dürrheim
country: Germany
facility: Boehringer Ingelheim
city: Bad Ems
country: Germany
facility: Boehringer Ingelheim
city: Bad Essen
country: Germany
facility: Boehringer Ingelheim
city: Bad Kreuznach
country: Germany
facility: Boehringer Ingelheim
city: Bad Laasphe
country: Germany
facility: Boehringer Ingelheim
city: Bad Langensalza
country: Germany
facility: Boehringer Ingelheim
city: Bad Lausick
country: Germany
facility: Boehringer Ingelheim
city: Bad Münstereifel
country: Germany
facility: Boehringer Ingelheim
city: Bad Oeynhausen
country: Germany
facility: Boehringer Ingelheim
city: Bad Salzungen
country: Germany
facility: Boehringer Ingelheim
city: Bad Schwalbach
country: Germany
facility: Boehringer Ingelheim
city: Bad Schwartau
country: Germany
facility: Boehringer Ingelheim
city: Bad Segeberg
country: Germany
facility: Boehringer Ingelheim
city: Bad Tennstedt
country: Germany
facility: Boehringer Ingelheim
city: Bad Waldsee
country: Germany
facility: Boehringer Ingelheim
city: Baden-Baden
country: Germany
facility: Boehringer Ingelheim
city: Bahrdorf
country: Germany
facility: Boehringer Ingelheim
city: Baltmannsweiler
country: Germany
facility: Boehringer Ingelheim
city: Bamberg
country: Germany
facility: Boehringer Ingelheim
city: Barleben
country: Germany
facility: Boehringer Ingelheim
city: Baunatal
country: Germany
facility: Boehringer Ingelheim
city: Bautzen
country: Germany
facility: Boehringer Ingelheim
city: Bayreuth
country: Germany
facility: Boehringer Ingelheim
city: Beckum
country: Germany
facility: Boehringer Ingelheim
city: Beeskow
country: Germany
facility: Boehringer Ingelheim
city: Bellheim
country: Germany
facility: Boehringer Ingelheim
city: Belm
country: Germany
facility: Boehringer Ingelheim
city: Bensheim
country: Germany
facility: Boehringer Ingelheim
city: Berching
country: Germany
facility: Boehringer Ingelheim
city: Bergfelde
country: Germany
facility: Boehringer Ingelheim
city: Bergheim
country: Germany
facility: Boehringer Ingelheim
city: Bergisch Gladbach
country: Germany
facility: Boehringer Ingelheim
city: Berkheim
country: Germany
facility: Boehringer Ingelheim
city: Berlin
country: Germany
facility: Boehringer Ingelheim
city: Berne
country: Germany
facility: Boehringer Ingelheim
city: Bernsdorf
country: Germany
facility: Boehringer Ingelheim
city: Betzdorf
country: Germany
facility: Boehringer Ingelheim
city: Biebertal
country: Germany
facility: Boehringer Ingelheim
city: Bielefeld
country: Germany
facility: Boehringer Ingelheim
city: Bienenbüttel
country: Germany
facility: Boehringer Ingelheim
city: Bippen
country: Germany
facility: Boehringer Ingelheim
city: Birkenfeld
country: Germany
facility: Boehringer Ingelheim
city: Birkenwerder
country: Germany
facility: Boehringer Ingelheim
city: Blankenhain
country: Germany
facility: Boehringer Ingelheim
city: Blaustein
country: Germany
facility: Boehringer Ingelheim
city: Blieskastel
country: Germany
facility: Boehringer Ingelheim
city: Bobritzsch
country: Germany
facility: Boehringer Ingelheim
city: Bocholt
country: Germany
facility: Boehringer Ingelheim
city: Bochum
country: Germany
facility: Boehringer Ingelheim
city: Bockenem
country: Germany
facility: Boehringer Ingelheim
city: Bodelshausen
country: Germany
facility: Boehringer Ingelheim
city: Bodenfelde
country: Germany
facility: Boehringer Ingelheim
city: Bodenkirchen
country: Germany
facility: Boehringer Ingelheim
city: Bodenwöhr
country: Germany
facility: Boehringer Ingelheim
city: Bodman-Ludwigshafen
country: Germany
facility: Boehringer Ingelheim
city: Bollendorf
country: Germany
facility: Boehringer Ingelheim
city: Bonn
country: Germany
facility: Boehringer Ingelheim
city: Bopfingen
country: Germany
facility: Boehringer Ingelheim
city: Borgholzhausen
country: Germany
facility: Boehringer Ingelheim
city: Borken
country: Germany
facility: Boehringer Ingelheim
city: Borna
country: Germany
facility: Boehringer Ingelheim
city: Bornheim
country: Germany
facility: Boehringer Ingelheim
city: Bottendorf
country: Germany
facility: Boehringer Ingelheim
city: Bottmersdorf
country: Germany
facility: Boehringer Ingelheim
city: Bottrop
country: Germany
facility: Boehringer Ingelheim
city: Bovenden
country: Germany
facility: Boehringer Ingelheim
city: Brake
country: Germany
facility: Boehringer Ingelheim
city: Brandenburg
country: Germany
facility: Boehringer Ingelheim
city: Brannenburg
country: Germany
facility: Boehringer Ingelheim
city: Braunschweig
country: Germany
facility: Boehringer Ingelheim
city: Brechen
country: Germany
facility: Boehringer Ingelheim
city: Breitenbrunn
country: Germany
facility: Boehringer Ingelheim
city: Bremen
country: Germany
facility: Boehringer Ingelheim
city: Bremerhaven
country: Germany
facility: Boehringer Ingelheim
city: Brensbach
country: Germany
facility: Boehringer Ingelheim
city: Breuberg
country: Germany
facility: Boehringer Ingelheim
city: Bruchköbel
country: Germany
facility: Boehringer Ingelheim
city: Brunsbüttel
country: Germany
facility: Boehringer Ingelheim
city: Buchbach
country: Germany
facility: Boehringer Ingelheim
city: Buckow
country: Germany
facility: Boehringer Ingelheim
city: Bunde
country: Germany
facility: Boehringer Ingelheim
city: Burgau
country: Germany
facility: Boehringer Ingelheim
city: Burgdorf
country: Germany
facility: Boehringer Ingelheim
city: Burgpreppach
country: Germany
facility: Boehringer Ingelheim
city: Burg
country: Germany
facility: Boehringer Ingelheim
city: Burtenbach
country: Germany
facility: Boehringer Ingelheim
city: Buttstädt
country: Germany
facility: Boehringer Ingelheim
city: Butzbach
country: Germany
facility: Boehringer Ingelheim
city: Bärnau
country: Germany
facility: Boehringer Ingelheim
city: Böhlen
country: Germany
facility: Boehringer Ingelheim
city: Bösel
country: Germany
facility: Boehringer Ingelheim
city: Bückeburg
country: Germany
facility: Boehringer Ingelheim
city: Büdelsdorf
country: Germany
facility: Boehringer Ingelheim
city: Büttelborn
country: Germany
facility: Boehringer Ingelheim
city: Cadolzburg
country: Germany
facility: Boehringer Ingelheim
city: Calberlah
country: Germany
facility: Boehringer Ingelheim
city: Calbe
country: Germany
facility: Boehringer Ingelheim
city: Castrop-Rauxel
country: Germany
facility: Boehringer Ingelheim
city: Celle
country: Germany
facility: Boehringer Ingelheim
city: Chemnitz
country: Germany
facility: Boehringer Ingelheim
city: Cochem
country: Germany
facility: Boehringer Ingelheim
city: Coppenbrügge
country: Germany
facility: Boehringer Ingelheim
city: Crimmitschau
country: Germany
facility: Boehringer Ingelheim
city: Crivitz
country: Germany
facility: Boehringer Ingelheim
city: Cuxhaven
country: Germany
facility: Boehringer Ingelheim
city: Dabel
country: Germany
facility: Boehringer Ingelheim
city: Darmstadt
country: Germany
facility: Boehringer Ingelheim
city: Dassow
country: Germany
facility: Boehringer Ingelheim
city: Datteln
country: Germany
facility: Boehringer Ingelheim
city: Daun
country: Germany
facility: Boehringer Ingelheim
city: Deggendorf
country: Germany
facility: Boehringer Ingelheim
city: Deidesheim
country: Germany
facility: Boehringer Ingelheim
city: Deining
country: Germany
facility: Boehringer Ingelheim
city: Delitzsch
country: Germany
facility: Boehringer Ingelheim
city: Demen
country: Germany
facility: Boehringer Ingelheim
city: Denkendorf
country: Germany
facility: Boehringer Ingelheim
city: Dessau
country: Germany
facility: Boehringer Ingelheim
city: Detmold
country: Germany
facility: Boehringer Ingelheim
city: Dettenheim
country: Germany
facility: Boehringer Ingelheim
city: Deuben
country: Germany
facility: Boehringer Ingelheim
city: Deutzen
country: Germany
facility: Boehringer Ingelheim
city: Diepholz
country: Germany
facility: Boehringer Ingelheim
city: Dillingen
country: Germany
facility: Boehringer Ingelheim
city: Dingolfing
country: Germany
facility: Boehringer Ingelheim
city: Dinkelsbühl
country: Germany
facility: Boehringer Ingelheim
city: Dinslaken
country: Germany
facility: Boehringer Ingelheim
city: Dissen
country: Germany
facility: Boehringer Ingelheim
city: Dogern
country: Germany
facility: Boehringer Ingelheim
city: Dollern
country: Germany
facility: Boehringer Ingelheim
city: Donaueschingen
country: Germany
facility: Boehringer Ingelheim
city: Dormagen
country: Germany
facility: Boehringer Ingelheim
city: Dornstetten
country: Germany
facility: Boehringer Ingelheim
city: Dorsten
country: Germany
facility: Boehringer Ingelheim
city: Dortmund
country: Germany
facility: Boehringer Ingelheim
city: Dreieich
country: Germany
facility: Boehringer Ingelheim
city: Drensteinfurt
country: Germany
facility: Boehringer Ingelheim
city: Dresden
country: Germany
facility: Boehringer Ingelheim
city: Driedorf
country: Germany
facility: Boehringer Ingelheim
city: Duderstadt
country: Germany
facility: Boehringer Ingelheim
city: Duisburg
country: Germany
facility: Boehringer Ingelheim
city: Dummerstorf
country: Germany
facility: Boehringer Ingelheim
city: Dörentrup
country: Germany
facility: Boehringer Ingelheim
city: Dörpen
country: Germany
facility: Boehringer Ingelheim
city: Düren
country: Germany
facility: Boehringer Ingelheim
city: Düsseldorf
country: Germany
facility: Boehringer Ingelheim
city: Ebergötzen
country: Germany
facility: Boehringer Ingelheim
city: Ebermannstadt
country: Germany
facility: Boehringer Ingelheim
city: Eberstadt
country: Germany
facility: Boehringer Ingelheim
city: Ebhausen
country: Germany
facility: Boehringer Ingelheim
city: Edewecht
country: Germany
facility: Boehringer Ingelheim
city: Edling
country: Germany
facility: Boehringer Ingelheim
city: Egelsbach
country: Germany
facility: Boehringer Ingelheim
city: Ehingen
country: Germany
facility: Boehringer Ingelheim
city: Eilenburg
country: Germany
facility: Boehringer Ingelheim
city: Eisenhüttenstadt
country: Germany
facility: Boehringer Ingelheim
city: Eiterfeld
country: Germany
facility: Boehringer Ingelheim
city: Eitorf
country: Germany
facility: Boehringer Ingelheim
city: Ellwangen
country: Germany
facility: Boehringer Ingelheim
city: Elmshorn
country: Germany
facility: Boehringer Ingelheim
city: Emersacker
country: Germany
facility: Boehringer Ingelheim
city: Emmendingen
country: Germany
facility: Boehringer Ingelheim
city: Emsdetten
country: Germany
facility: Boehringer Ingelheim
city: Enger
country: Germany
facility: Boehringer Ingelheim
city: Enkenbach-Alsenborn
country: Germany
facility: Boehringer Ingelheim
city: Ennepetal
country: Germany
facility: Boehringer Ingelheim
city: Ennigerloh
country: Germany
facility: Boehringer Ingelheim
city: Eppstein
country: Germany
facility: Boehringer Ingelheim
city: Erding
country: Germany
facility: Boehringer Ingelheim
city: Erftstadt
country: Germany
facility: Boehringer Ingelheim
city: Erkrath
country: Germany
facility: Boehringer Ingelheim
city: Erligheim
country: Germany
facility: Boehringer Ingelheim
city: Erndtebrück
country: Germany
facility: Boehringer Ingelheim
city: Erolzheim
country: Germany
facility: Boehringer Ingelheim
city: Eschborn
country: Germany
facility: Boehringer Ingelheim
city: Eschelbronn
country: Germany
facility: Boehringer Ingelheim
city: Eschweiler
country: Germany
facility: Boehringer Ingelheim
city: Eslohe
country: Germany
facility: Boehringer Ingelheim
city: Espenhain
country: Germany
facility: Boehringer Ingelheim
city: Essen
country: Germany
facility: Boehringer Ingelheim
city: Esslingen
country: Germany
facility: Boehringer Ingelheim
city: Euskirchen
country: Germany
facility: Boehringer Ingelheim
city: Filderstadt
country: Germany
facility: Boehringer Ingelheim
city: Floh-Seligenthal
country: Germany
facility: Boehringer Ingelheim
city: Flöha
country: Germany
facility: Boehringer Ingelheim
city: Forbach
country: Germany
facility: Boehringer Ingelheim
city: Forchheim
country: Germany
facility: Boehringer Ingelheim
city: Frankenberg
country: Germany
facility: Boehringer Ingelheim
city: Frankenthal
country: Germany
facility: Boehringer Ingelheim
city: Frankfurt
country: Germany
facility: Boehringer Ingelheim
city: Freiberg
country: Germany
facility: Boehringer Ingelheim
city: Freiburg
country: Germany
facility: Boehringer Ingelheim
city: Freigericht
country: Germany
facility: Boehringer Ingelheim
city: Freudenstadt
country: Germany
facility: Boehringer Ingelheim
city: Freyung
country: Germany
facility: Boehringer Ingelheim
city: Friedland
country: Germany
facility: Boehringer Ingelheim
city: Friedrichshafen
country: Germany
facility: Boehringer Ingelheim
city: Friedrichsthal
country: Germany
facility: Boehringer Ingelheim
city: Frohburg
country: Germany
facility: Boehringer Ingelheim
city: Fulda
country: Germany
facility: Boehringer Ingelheim
city: Furtwangen
country: Germany
facility: Boehringer Ingelheim
city: Fürstenwalde
country: Germany
facility: Boehringer Ingelheim
city: Füssen
country: Germany
facility: Boehringer Ingelheim
city: Gangelt
country: Germany
facility: Boehringer Ingelheim
city: Gardelegen
country: Germany
facility: Boehringer Ingelheim
city: Garmisch-Partenkirchen
country: Germany
facility: Boehringer Ingelheim
city: Gars
country: Germany
facility: Boehringer Ingelheim
city: Gaußig
country: Germany
facility: Boehringer Ingelheim
city: Gebesee
country: Germany
facility: Boehringer Ingelheim
city: Geesthacht
country: Germany
facility: Boehringer Ingelheim
city: Gelbensande
country: Germany
facility: Boehringer Ingelheim
city: Gelsenkirchen
country: Germany
facility: Boehringer Ingelheim
city: Gensingen
country: Germany
facility: Boehringer Ingelheim
city: Georgsmarienhütte
country: Germany
facility: Boehringer Ingelheim
city: Gera
country: Germany
facility: Boehringer Ingelheim
city: Gerbstedt
country: Germany
facility: Boehringer Ingelheim
city: Germaringen
country: Germany
facility: Boehringer Ingelheim
city: Germering
country: Germany
facility: Boehringer Ingelheim
city: Germersheim
country: Germany
facility: Boehringer Ingelheim
city: Gevelsberg
country: Germany
facility: Boehringer Ingelheim
city: Gießen
country: Germany
facility: Boehringer Ingelheim
city: Gifhorn
country: Germany
facility: Boehringer Ingelheim
city: Gilserberg
country: Germany
facility: Boehringer Ingelheim
city: Gladbeck
country: Germany
facility: Boehringer Ingelheim
city: Gleichen
country: Germany
facility: Boehringer Ingelheim
city: Gochsheim
country: Germany
facility: Boehringer Ingelheim
city: Goch
country: Germany
facility: Boehringer Ingelheim
city: Gomaringen
country: Germany
facility: Boehringer Ingelheim
city: Grafenau
country: Germany
facility: Boehringer Ingelheim
city: Gransee
country: Germany
facility: Boehringer Ingelheim
city: Grassau
country: Germany
facility: Boehringer Ingelheim
city: Greiz
country: Germany
facility: Boehringer Ingelheim
city: Greven
country: Germany
facility: Boehringer Ingelheim
city: Grevesmühlen
country: Germany
facility: Boehringer Ingelheim
city: Griesheim
country: Germany
facility: Boehringer Ingelheim
city: Gronau
country: Germany
facility: Boehringer Ingelheim
city: Groß Grönau
country: Germany
facility: Boehringer Ingelheim
city: Groß Quenstedt
country: Germany
facility: Boehringer Ingelheim
city: Groß-Zimmern
country: Germany
facility: Boehringer Ingelheim
city: Großalmerode
country: Germany
facility: Boehringer Ingelheim
city: Großbottwar
country: Germany
facility: Boehringer Ingelheim
city: Großefehn
country: Germany
facility: Boehringer Ingelheim
city: Großhabersdorf
country: Germany
facility: Boehringer Ingelheim
city: Großkorbetha
country: Germany
facility: Boehringer Ingelheim
city: Großlangheim
country: Germany
facility: Boehringer Ingelheim
city: Grömitz
country: Germany
facility: Boehringer Ingelheim
city: Grünbach
country: Germany
facility: Boehringer Ingelheim
city: Gummersbach
country: Germany
facility: Boehringer Ingelheim
city: Göllheim
country: Germany
facility: Boehringer Ingelheim
city: Göllingen
country: Germany
facility: Boehringer Ingelheim
city: Göttingen
country: Germany
facility: Boehringer Ingelheim
city: Güstrow
country: Germany
facility: Boehringer Ingelheim
city: Haag
country: Germany
facility: Boehringer Ingelheim
city: Hagen
country: Germany
facility: Boehringer Ingelheim
city: Haigerloch
country: Germany
facility: Boehringer Ingelheim
city: Haldensleben
country: Germany
facility: Boehringer Ingelheim
city: Halle
country: Germany
facility: Boehringer Ingelheim
city: Hamburg
country: Germany
facility: Boehringer Ingelheim
city: Hamminkeln
country: Germany
facility: Boehringer Ingelheim
city: Hamm
country: Germany
facility: Boehringer Ingelheim
city: Hanau
country: Germany
facility: Boehringer Ingelheim
city: Hanerau-Hademarschen
country: Germany
facility: Boehringer Ingelheim
city: Hannover
country: Germany
facility: Boehringer Ingelheim
city: Harpstedt
country: Germany
facility: Boehringer Ingelheim
city: Harsefeld
country: Germany
facility: Boehringer Ingelheim
city: Harsewinkel
country: Germany
facility: Boehringer Ingelheim
city: Haselünne
country: Germany
facility: Boehringer Ingelheim
city: Hattersheim
country: Germany
facility: Boehringer Ingelheim
city: Hattingen
country: Germany
facility: Boehringer Ingelheim
city: Havixbeck
country: Germany
facility: Boehringer Ingelheim
city: Hedersleben
country: Germany
facility: Boehringer Ingelheim
city: Heek
country: Germany
facility: Boehringer Ingelheim
city: Heidelberg
country: Germany
facility: Boehringer Ingelheim
city: Heide
country: Germany
facility: Boehringer Ingelheim
city: Heilbronn
country: Germany
facility: Boehringer Ingelheim
city: Heimsheim
country: Germany
facility: Boehringer Ingelheim
city: Heinsberg
country: Germany
facility: Boehringer Ingelheim
city: Hellenthal
country: Germany
facility: Boehringer Ingelheim
Study officials:
affiliation: Boehringer Ingelheim
name: Boehringer Ingelheim
role: STUDY_CHAIR
References: