Clinical trial NCT05269095: Adductor Canal Block Combined With IPACK vs Genicular Nerves Block in Knee Arthroscopy
Official title: Analgesic Effect of Adductor Canal Block Combined With Infiltration of the Interspace Between Popliteal Artery and the Capsule of the Knee (IPACK) Block Versus Genicular Nerves Block in Knee Arthroscopy
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Arthroscopy
Genicular Nerves Block
Lead sponsor: Tanta University
Sponsor class: OTHER
First posted: 2022-03-07
Enrollment: 105
Sex: ALL
Minimum age (years): 21
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This prospective randomized controlled study is designed to investigate the postoperative analgesic effect of adductor canal block (ACB) combined with infiltration of the interspace between the popliteal artery and the capsule of posterior knee (IPACK) block compared to genicular nerves block in patients undergoing knee arthroscopy.

Detailed description: Maintaining patient safety, ensuring best patient outcomes, and optimal pain relief post-operatively are of utmost concern for anesthesia providers. Adequate pain relief attenuates stress responses and long-term chronic pain complications while contributing to improved postoperative outcomes.

Knee arthroscopy is a very common procedure and very often is performed as day-case surgery. Ambulatory arthroscopic surgery of the knee is preferred by the majority of properly selected and well-informed patients. It has been reported that a significant number of patients have moderate to severe pain 24 hours after ambulatory surgery in general and knee arthroscopy in particular and pain affects the patient's activity level and satisfaction. Adductor canal block (ACB) is a popular peripheral nerve block that has been shown to decrease the pain significantly and decrease opioid consumption with minimal effect on quadriceps function. It provides analgesia to the peri-articular and intra-articular aspects of the knee joint but doesn't relieve posterior knee pain which is moderate to severe in intensity.

Eligibility criteria: Inclusion Criteria:

* Age 21-60 years
* Both genders
* American Society of Anaesthesiologists physical status classification I - III
* Patients scheduled for elective unilateral knee arthroscopy under spinal anesthesia

Exclusion Criteria:

* Patient refusal
* Preoperative neurological deficits
* Opioid-dependent (opioid intake more than 3 months)
* Chronic pain conditions
* Significant cardiac and respiratory disease
* Pre-existing major organ dysfunction such as hepatic and renal failure
* Coexisting hematological disorder or deranged coagulation parameters
* Psychiatric illnesses
* Allergy to any of the drugs used in the study

Primary outcomes:
measure: Postoperative 24-hour rescue analgesic consumption
timeFrame: 24 hours postoperative
Secondary outcomes:
measure: Post-operative pain
timeFrame: 24 hours Postoperative
measure: Time taken till 1st rescue analgesic request
timeFrame: 24 hours Postoperative
Other outcomes:
Locations:
Study officials:
References: