Clinical trial NCT03668210: Risk Factor of Anterior Cruciate Ligament Rupture After Ligamentoplasty : What is the Importance of a Relative Deficit of Contralateral Hamstrings Assessed by Isokinetic in Postoperative ?
Official title: Risk Factor of Anterior Cruciate Ligament Rupture After Ligamentoplasty : What is the Importance of a Relative Deficit of Contralateral Hamstrings Assessed by Isokinetic in Postoperative ?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Anterior Cruciate Ligament Rupture
Keywords: Anterior cruciate ligament
ligamentoplasty
isokinetics
Lead sponsor: Rennes University Hospital
Sponsor class: OTHER
First posted: 2018-09-12
Enrollment: 141
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Athletic patients who have consulted in Sports Medicine Department at Rennes University Hospital

Brief summary: Anterior cruciate ligament (ACL) is a common pathology (37 000 operations in 2006, nearly 43 000 in 2012 in France) justifying more and more operating indications in younger and younger patients. 70-80% of ACL ruptures occur without contact, which makes it a major public health interest because of its frequency and accessibility in terms of prevention.

The place of isokinetic assessment is important pre and postoperatively so that it has become systematic.

Detailed description: The main risk factors for known ACL lesions are female gender, pivotal sports, neuromuscular deficits, proprioceptive, hormonal, morphological deficits ... Moreover, there is also an increase in the number of contralateral fractures in patients who had a ligamentoplasty. There are many articles on the ACL pathology but unequal on the potential risk factors. The only proven risk factor for contralateral rupture is the age of the first episode; the female sex also seems to be important in some studies but remains more controversial. However, many factors have been studied: the intensity of the sport, the sex, the operative technique of ligamentoplasty, the operating duration, the duration of recovery of the sports activity, the level of recovery (of this sporting activity ) ...

Isokinetics is used to measure the peak of strength of quadriceps and hamstrings, in concentric or eccentric, at slow and fast speed and to determine a hamstring / quadriceps ratio to highlight a deficit or imbalance.

Eligibility criteria: Inclusion Criteria:

* Athletic patients all levels
* victims of ACL rupture during sports practice,
* operated by the same surgeon
* having been evaluated in isokinetic postoperative in the Sports Medicine Department of Rennes University Hospital
* having resumed a sporting activity
* with the first ACL rupture between 01/01/1994 and 12/31/2015

Exclusion Criteria:

* Patients with ACL rupture outside of a sporting context
* not having resumed post-operative sports activity on the maximum follow-up period of 15 years
* not evaluated for isokinetic activity in the sports medicine department
* minors at the time of inclusion

Primary outcomes:
measure: Evaluation of relative hamstrings deficiency versus quadriceps expressed by a concentric hamstrings/quadriceps ratio
timeFrame: At inclusion
Secondary outcomes:
measure: Investigating whether a lack of recruitment of hamstring at fast speed is a potential risk factor for ACL rupture, by evaluating hamstrings/quadriceps ratio in isokinetics.
timeFrame: At inclusion
Other outcomes:
Locations:
city: Rennes
country: France
facility: Rennes University Hospital
Study officials:
affiliation: Rennes University Hospital
name: Jacqueline JAN, MD
role: PRINCIPAL_INVESTIGATOR
References: