Clinical trial NCT01998282: Evaluation of a Project to Distribute Water Filters and Cook Stoves in Western Rwanda--Phase 1B
Official title: Assessing the Impact of Water Filters and Improved Cook Stoves on Drinking Water and Quality and Indoor Air Pollution: A Matched Cohort Study in Rwanda
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Focus of Study is to Assess Filter and Stove Use and Efficacy in Reducing Exposure to Waterborne and Airborne Pathogens
Keywords: Focus of study is to assess filter/stove use and efficacy in reducing exposure to waterborne and airborne pathogens.
Lead sponsor: London School of Hygiene and Tropical Medicine
Sponsor class: OTHER
Collaborators: name: Ministry of Health, Rwanda
name: DelAgua
name: Portland State University
name: University of Colorado, Boulder
First posted: 2013-11-28
Enrollment: 1035
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Lower income (ubudehe groups 1 and 2) householders from 18 villages (9 intervention and matched controls) in 11 designated Districts in Rwanda: Rutsiro, Karongi, Ngororero, Nyamasheke, Nyabihu Districts of Western Province (excluding part of the district to the north of the Ruhengeri road); Rubuvu District (excluding part of the district to the north of the Ruhengeri road); Nyaruguru, Nyamagabe, Muhanga, and Ruhango Districts in Southern Province; Gakenke District in Northern Province.

Brief summary: DelAgua Health and Development, Manna Energy and the Rwanda Ministry of Health are collaborating on a project financed by carbon credits that will distribute household-based water filters and high-efficiency cook stoves to approximately 600,000 households in Rwanda. Prior to the full roll out of the campaign, the implementers are conducting research in connection with a distribution among 2000 households in western Rwanda. The objective of this matched cohort study (Phase 1B)are to investigate whether the filters and stoves delivered in October 2012 are still performing and in use, to determine whether they are associated with reductions in exposure to pathogens from drinking water and stoves, and to assembly information on health and other conditions necessary for the design of a large scale health impact evaluation.


Eligibility criteria: Households will be eligible to participate in the study if they reside in selected villages and are willing to participate after receiving complete details regarding the study. Intervention households must have a functioning stove and water filter in order to participate, though they do not need to be in regular use. We will enroll all households with a child under 5 years of age if they are in Ubudehe groups 1 or 2.

Primary outcomes:
measure: Personal exposure to PM2.5 and CO (mg/m3)
timeFrame: 10 months
Secondary outcomes:
measure: Thermotolerant coliforms (TTC) in colony forming units (CFU) per 100ml of sample water
timeFrame: 10 months
Other outcomes:
measure: Blood pressure
timeFrame: 10 months
measure: Blood pressure covariates
timeFrame: 10 months
measure: Use of filter and stove
timeFrame: 10 months
measure: Exposure to PM2.5 and CO in primary cooking areas (mg/m3)
timeFrame: 10 months
Locations:
city: Kigali
country: Rwanda
facility: DelAgua Health Rwanda
state: PO Box 1594
Study officials:
affiliation: London School of Hygiene and Tropical Medicine
name: Thomas F Clasen, PhD
role: PRINCIPAL_INVESTIGATOR
References: