Clinical trial NCT03931512: TDCS Effects on Motor Learning and Motor Control in Healthy Subjetcs
Official title: Transcranial Direct Current Stimulation Effects on Motor Learning and Motor Control in Healthy Subjetcs
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: transcranial direct current stimulation
motor learning
Lead sponsor: Centro Universitario La Salle
Sponsor class: OTHER
First posted: 2019-04-30
Enrollment: 33
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Clinical Trial with two groups, transcranial direct current stimulation aplication and sham; triple blinded. The protocol is applied 5 consecutive days during the training of a manual dexterity task. Manual dexterity and somatosensory variables are measured pre intervention, post one day of intervention, post 5 days of intervention, and 5 days after finish the intervention.

Detailed description: Clinical Trial with two groups, transcranial direct current stimulation aplication (1 mA ) and sham (ramp up and down of 30 seconds in total) . Bouth interventions will last 20 minutes; at the same time of the aplication bouth are going to train the manual dexterity with Purdue Pegboard Test.

This protocol is applied 5 consecutive days, also it have a follow up of 5 days more.

It is triple blinded. Manual dexterity and somatosensory variables are measured pre intervention, post one day of intervention, post 5 days of intervention, and 5 days after finish the intervention.

Eligibility criteria: Inclusion Criteria:

* healthy volunteers

Exclusion Criteria:

* metal or skin lesions on the head
* brain stimulation in the last 6 months
* family history of epilepsy or seizures
* pacemaker or any cardiac involvement
* inability to understand or execute the task
* taking drugs that may influence cognition
* pregnancy

Primary outcomes:
measure: Change in trained manual dexterity of the dominant hand
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
Secondary outcomes:
measure: Changes in trained manual dexterity of bouth hands
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
measure: Changes in maximal isometric hand grip force
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
measure: Sleep Quality
timeFrame: 5 days after finish the intervention
measure: Physical activity
timeFrame: 5 days after finish the intervention
measure: Changes in nontrained manual dexterity of the dominant hand
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
measure: Changes in nontrained manual dexterity of bouth hands
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
measure: Changes in pressure detection treshold
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
measure: Changes in pain detection treshold
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
measure: Changes in two points discrimination
timeFrame: pre intervention, post one day of intervention, post 5 days of intervention, 5 days after finish the intervention
Other outcomes:
Locations:
city: Madrid
country: Spain
facility: CEULaSalle
Study officials:
affiliation: University Studies Center La Salle
name: Sergio Lerma Lara, PhD
role: PRINCIPAL_INVESTIGATOR
References: