Clinical trial NCT05329272: Virtual Reality Training Intervention on Cognitive Function and Quality of Life
Official title: Effects of Incorporating Virtual Reality Training Intervention Into Health Care on Cognitive Function and Quality of Life in Older Adults With Cognitive Impairment: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Virtual Reality
Cognitive Impairment
Quality of Life
Keywords: Virtual Reality
Cognitive Impairment
Quality of Life
Long-term care facilities
Lead sponsor: I-Shou University
Sponsor class: OTHER
First posted: 2022-04-14
Enrollment: 60
Sex: ALL
Minimum age (years): 65
Maximum age (years): 99
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The present study aimed to investigate the effects of a Virtual Reality cognitive training intervention (VRCTI) on cognitive function changes measured with a cognitive test battery and improvement of quality of life in older adults with cognitive impairment in long-term care facilities. Weekly 1-hour sessions were implemented over 8 weeks targeting sustained and selective attention, memory, cognitive functions, and rule deduction. The passive control group received usual care.

Detailed description: Objectives: The present study aimed to investigate the effects of a Virtual Reality cognitive training intervention (VRCTI) on cognitive function changes measured with a cognitive test battery and improvement of quality of life in older adults with cognitive impairment in long-term care facilities.

Method: Weekly 1-hour sessions were implemented over 8 weeks targeting sustained and selective attention, memory, cognitive functions, and rule deduction. The VRCTI comprised 12 different tasks distributed in 8 sessions with different difficulty levels. The passive control group received usual care. Older adults were randomly assigned to either VR or control groups. An experimental pre-post design was used. Accuracy, error, and repetition rates were measured throughout each session. Intervention effects were analyzed using a generalized estimating equation model.

Eligibility criteria: Inclusion Criteria:

* Aged ≥ 65 years
* Admitted as residents at the study-site institutions (long-term care facilities)
* Mini Mental Status Examination (MMSE) ≥ 13
* Able to communicate sufficiently

Exclusion Criteria:

* Open facial wounds
* Problems with a finger, hand, or wrist and/or major visual or auditory impairment, making it difficult to deliver training scheme
* Major neurological or psychiatric conditions that may affect cognition (e.g., stroke, dizziness, schizophrenia)
* Unstable medical conditions
* Were unable to comply with the intervention

Primary outcomes:
measure: Cognitive Assessment Screening Instrument (CASI)
timeFrame: Change is being assessed. Change in Cognitive Assessment Screening Instrument (CASI) from baseline to immediately after the intervention.
measure: Mini-Mental State Examination (MMSE)
timeFrame: Change is being assessed. Change in Mini-Mental State Examination (MMSE) from baseline to immediately after the intervention.
measure: Clock Drawing Test-Drawing Part, (CDT-D)
timeFrame: Change is being assessed. Change in Clock Drawing Test-Drawing Part, (CDT-D) from baseline to immediately after the intervention.
measure: World Health Organization Quality of Life Scale Brief Version (WHOQOL-BREF)
timeFrame: Change is being assessed. Change in World Health Organization Quality of Life Scale Brief Version (WHOQOL-BREF) from baseline to immediately after the intervention.
Secondary outcomes:
Other outcomes:
Locations:
city: Kaohsiung City
country: Taiwan
facility: I-Shou University
Study officials:
affiliation: I-Shou University
name: Mei-Chi Hsu, Ph.D
role: PRINCIPAL_INVESTIGATOR
References: