Clinical trial NCT06472882: Impact of Transcranial Direct Current Stimulation on the Capacity to Perform Burpees
Official title: Impact of Transcranial Direct Current Stimulation on the Capacity to Perform Burpees: a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Transcranial Direct Current Stimulation
Dorsolateral Prefrontal Cortex
Primary Motor Cortex
Keywords: Primary motor cortex
dorsolateral prefrontal cortex
physical endurance
tDCS
Lead sponsor: Universidad Católica San Antonio de Murcia
Sponsor class: OTHER
Collaborators: name: University of A Coruna, La Coruna, Spain
First posted: 2024-06-25
Enrollment: 20
Sex: MALE
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The study applied a double-blind, crossover design to examine the viability of tDCS in improving performance during a maximal effort task, particularly the "No Jump Burpee" exercise.
Primary purpose: BASIC_SCIENCE

Brief summary: Introduction and Background:

Transcranial direct current stimulation (tDCS) has emerged as a potential intervention to improve physical performance. The primary aim of this study is to investigate the effects of tDCS applied to the primary motor cortex (M1) and dorsolateral prefrontal cortex (DLPFC) on performance in a maximal effort task, specifically the No Jump Burpee exercise.

Study Design:

This study will utilize a double-blind crossover design, where each subject will complete three experimental conditions: a-DLPFC, a-M1, and SHAM.

Participants:

Twenty healthy male subjects will be recruited for the study.

Intervention:

Each participant will undergo three conditions in a randomized order:

a-DLPFC: tDCS applied to the dorsolateral prefrontal cortex.

a-M1: tDCS applied to the primary motor cortex. SHAM: Placebo stimulation.

Procedure:

Prior to performing the No Jump Burpee exercise to exhaustion, tDCS will be administered at a current of 2 milliampere (mA) for 20 minutes.

Measurements:

The following variables will be measured during the exercise:

Total number of repetitions of the No Jump Burpee exercise. Vastus lateralis muscle oxygen saturation. Heart rate. Subjective perception of exertion (RPE).

Data Analysis:

Repeated measures ANOVAs will be used to analyze the effects of the different tDCS conditions on the performance outcomes.

Ethical Considerations:

The study protocol will be reviewed and approved by an appropriate ethics committee. Written informed consent will be obtained from all participants before participation in the study.

Objectives:

The primary objective is to evaluate the impact of tDCS on physical performance, specifically measuring the total number of repetitions of the No Jump Burpee exercise. Secondary objectives include assessing the changes in muscle oxygen saturation, heart rate, and subjective perception of exertion.


Eligibility criteria: Inclusion Criteria:

* Healthy subject.
* No use of any ergogenic substance.
* Participants must be recreationally active, defined as engaging in moderate physical activity at least 3 times per week for the past 6 months

Exclusion Criteria:

* Any contraindications to transcranial Direct Current Stimulation, such as metallic implants in the head, active implanted medical devices (e.g., pacemakers), or skin conditions affecting the scalp.
* Current or recent (within the past 6 months) substance abuse, including alcohol or recreational drugs.
* Musculoskeletal injury within the past 6 weeks.
* Lower extremity pain above 3 or more according to numeric pain scale.
* History of epilepsy or convulsive crisis.

Primary outcomes:
measure: Number of "No Jump Burpees" to Exhaustion
timeFrame: Measured immediately at the end of each experimental session (DLPFC, M1, SHAM), approximately 5-10 minutes after the start of the test..
Secondary outcomes:
measure: Rating of Perceived Exertion (RPE)
timeFrame: Measured every 20 seconds during exercise, from the start until the participant reaches exhaustion, approximately 5-15 minutes per session.
measure: Muscle Oxygen Saturation in the Vastus Lateralis
timeFrame: Measured continuously at a frequency of 1 Hz during the exercise, from the start until the participant reaches exhaustion, approximately 5-15 minutes per session.
measure: Heart Rate During Exercise
timeFrame: Measured continuously on a beat-by-beat basis during the exercise, from the start until the participant reaches exhaustion, approximately 5-15 minutes per session.
Other outcomes:
measure: Mood State Before Exercise
timeFrame: Before each experimental session.
measure: Anxiety Level Before Exercise
timeFrame: Before each experimental session
measure: Sleep Quality on the Night Prior to Exercise
timeFrame: Before each experimental session.
Locations:
city: Guadalupe
country: Spain
facility: Catholic University of Murcia
state: Murcia
Study officials:
References: