Clinical trial NCT05584527: Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake
Official title: Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Eating Habit
Cold Exposure
Heat
Keywords: Heat Exposure
Food Intake
Lead sponsor: Direction Centrale du Service de Santé des Armées
Sponsor class: OTHER
First posted: 2022-10-18
Enrollment: 24
Sex: MALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population will be composed of young and healthy men.

Brief summary: Military personnel and athletes have a very high energy expenditure which is increased during certain key periods (intense training, competition and mission). Compensating for this expenditure through food can be complicated by physiological ingestive limits and logistical and organizational constraints (number of meals, availability of food), which leads these populations to regularly experience energy deficit situations (intake below requirements), which could alter physical and cognitive performance and major physiological functions.

Among the many constraints to which military personnel and athletes are exposed to (stress, sleep deprivation, travel, etc.) that can increase the risk of energy deficits, the impact of thermal environmental constraints is not well known. The seasonal impact and travel to countries with very different thermal environments can lead these populations to experience cold and hot conditions for long periods.

Understanding how heat and cold exposure modifies appetite and energy intake therefore appears to be of great importance.

The hypothesis of this study is that a 24 h heat exposure would produce a rapid and long-lasting anorexigenic action impacting energy intake, while a cold exposure would produce the opposite effect (orexigenic action).


Eligibility criteria: Inclusion Criteria:

* Male
* Aged 18 to 40 years old
* Active (≥ 3 hours of physical activity per week)
* Healthy (no metabolic pathology)
* Affiliated to the social security system
* Having given written consent to participate.

Exclusion Criteria:

* Unusual eating pattern (\< 3 meals per day) or irregular eating pattern
* Pattern of dietary restriction (determined by the Three-Factor Eating Questionnaire-21)
* Unusual sleep pattern (Epworth score \> 10, insomnia severity score \> 14, Pittsburgh Sleep Quality Index \> 5), sleep duration \< 6 h per night or difficulty falling asleep)
* Metabolic pathology
* On medication
* Previously exposed to unusual levels of heat or cold (vacation, missions) in the 4 months prior to inclusion
* Refusal to participate.

Primary outcomes:
measure: Total energy intake (in kilojoules) measured at the end of each condition (heat exposure, cold exposure and thermoneutral exposure)
timeFrame: Through study completion (30 months)
Secondary outcomes:
Other outcomes:
Locations:
city: Brétigny-sur-Orge
country: France
facility: Institut de Recherche Biomédicale des Armées
Study officials:
References: