Clinical trial NCT06686212: Comparative Effects of Sensory Re-education and Neural Mobilization in CTS Patients
Official title: Comparative Effects of Sensory Re-education and Neural Mobilization in Carpal Tunnel Syndrome Patients
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Carpal Tunnel Syndrome (CTS)
Keywords: Carpal tunnel syndrome, Grip strength, Sensory reeducation,
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-11-13
Enrollment: 48
Sex: ALL
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of study is to compare the effects of sensory re-education and neural mobilization in CTS patients.

Detailed description: This study will be randomized clinical trial that will be conducted at Services Hospital Lahore and Government Teaching Hospital Shahdara. In this study 48 participants with CTS will be included as per sample size calculation through non-probability convenience sampling technique. Participants that achieve the required standards of inclusion and exclusion criteria will be randomly allocated using online randomization tool into two groups. Group A will receive Sensory Re-education therapy, strengthening exercises and Kinesio taping for 60 minutes, Group B will be given neural mobilization techniques, strengthening exercises and Kinesio taping for 60 minutes with short rest intervals. Both treatments will be given 3 days per week for 12 weeks.

Eligibility criteria: Inclusion Criteria:

* Patients of both genders age 20-50 years with mild and moderate carpal tunnel syndrome.
* Patients having positive score on CTS specific test (Phalen's test and Tinel's test).
* Patients with pain, paresthesia and hyperesthesia at the course of median nerve.
* Patients that are clinically diagnosed with carpal tunnel syndrome by physician. Patients having BMI \>25 (kg/m2).

Exclusion Criteria:

* Patients with polyneuropathies.
* Patients with carpal tunnel syndrome due to any systemic illness (diabetes mellitus, thyroid diseases and R.A).

Patients having cervical radiculopathy.

Patients with history of wrist fracture.

Patients getting steroid injections and after CTS surgery.

Obese and pregnant female with carpal tunnel syndrome.

Patients with any cognitive or neurological problems are excluded from study.

Primary outcomes:
measure: Numerical pain rating scale
timeFrame: 12th week
measure: Boston Carpal Tunnel Questionnaire
timeFrame: 12th week
measure: Hand Held Dynamometer
timeFrame: 12th week
measure: Pinch gauge meter
timeFrame: 12th week
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Riphah International University Lahore Punjab, Pakistan
name: Muhammad Kashif, Phd
role: STUDY_CHAIR
References:
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citation: Lam NW, Goh HT, Kamaruzzaman SB, Chin AV, Poi PJ, Tan MP. Normative data for hand grip strength and key pinch strength, stratified by age and gender for a multiethnic Asian population. Singapore Med J. 2016 Oct;57(10):578-584. doi: 10.11622/smedj.2015164. Epub 2015 Nov 13.
citation: Almasi-Doghaee M, Boostani R, Saeedi M, Ebrahimzadeh S, Moghadam-Ahmadi A, Saeedi-Borujeni MJ. Carpal compression, Phalen's and Tinel's test: Which one is more suitable for carpal tunnel syndrome? Iran J Neurol. 2016 Jul 6;15(3):173-4. No abstract available.
citation: Du J, Yuan Q, Wang XY, Qian JH, An J, Dai Q, Yan XY, Xu B, Luo J, Wang HZ. Manual Therapy and Related Interventions for Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis. J Integr Complement Med. 2022 Dec;28(12):919-926. doi: 10.1089/jicm.2022.0542. Epub 2022 Jul 27.
citation: Ijaz MJ, Karimi H, Ahmad A, Gillani SA, Anwar N, Chaudhary MA. Comparative Efficacy of Routine Physical Therapy with and without Neuromobilization in the Treatment of Patients with Mild to Moderate Carpal Tunnel Syndrome. Biomed Res Int. 2022 Jun 22;2022:2155765. doi: 10.1155/2022/2155765. eCollection 2022.