Clinical trial NCT00860314: Antero-posterior Versus Antero-lateral Electrode Position for Electrical Cardioversion of Typical Atrial Flutter
Official title: Prospective, Randomized Single-center Study for Efficacy of Antero-posterior and Antero-lateral Electrode Position for External Electrical Cardioversion of Typical Atrial Flutter
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Atrial Flutter
Keywords: external electrical cardioversion
typical atrial flutter
electrode position
antero-lateral
antero-posterior
biphasic cardioversion
step-up protocol
Lead sponsor: Universitätsklinikum Hamburg-Eppendorf
Sponsor class: OTHER
First posted: 2009-03-12
Enrollment: 96
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study is to identify the one electrode position out of two most commonly used for external electrical cardioversion of typical atrial flutter, which needs less delivered energy and less needed number of shocks for successful cardioversion.

Detailed description: Typical atrial flutter is the second-most prevalent atrial tachyarrhythmia. No guidelines for treatment exist and few studies investigate treatment of atrial flutter. Mostly, guidelines for atrial fibrillation are followed for treatment of atrial flutter. Atrial flutter has a different pathomechanism as atrial fibrillation, therefore special guidelines for treatment are needed. Among drug treatment and ablation procedures, external electrical cardioversion is commonly used, especially for treatment of acute symptomatic patients. This study may help to further define safe and successful procedures for electrical cardioversion of atrial flutter.

Eligibility criteria: Inclusion Criteria:

* clinical diagnosis of typical atrial flutter
* signed written informed consent
* eligibility for sedation and external electrical cardioversion

Exclusion Criteria:

* clinical diagnosis of arrhythmia other than typical atrial flutter
* implanted ICD or pacemaker
* proof of atrial thrombi

Primary outcomes:
measure: Number of Successfully Cardioverted Participants for Each Electrode Position
timeFrame: 30 seconds after cardioversion
Secondary outcomes:
measure: Mean Number of Cardioversion Shocks
timeFrame: 30 seconds after cardioversion
measure: Mean Energy Requirement for Successful Cardioversion
timeFrame: 30 seconds after cardioversion
measure: Number of Participants Succesfully Cardioverted With First Shock in Each Electrode Position
timeFrame: 30 seconds after cardioversion
Other outcomes:
Locations:
city: Hamburg
country: Germany
facility: University Hospital Hamburg-Eppendorf, Heart Center
Study officials:
affiliation: Oberarzt
name: Stephan Willems, Prof. Dr.
role: STUDY_CHAIR
References:
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