Clinical trial NCT03826095: Respiratory Functions, Trunk Control and Mobility Evaluation in Multiple Sclerosis
Official title: Investigation of the Effects of Respiratory Functions and Trunk Control on Functional Mobility in Individuals With Multiple Sclerosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Physical Therapy
Keywords: Multiple Sclerosis
Respiratory function
Respiratory muscle strength
Trunk control
Functional mobility
Lead sponsor: Hacettepe University
Sponsor class: OTHER
Collaborators: name: KARMUTLU
name: MATUNCER
name: EÇKÜTÜKÇÜ
First posted: 2019-02-01
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: MS patients who are ambulatory

Healthy volunteer individuals of similar age and sex to patients

Brief summary: Respiratory functions and body control are affected in patients with multiple sclerosis (MS). Because of this effect, the dependency of individuals increases in daily living activities and their quality of life decreases.

We think that respiratory functions, respiratory muscle strength and trunk control affect vital mobility as well as vital importance for individuals with MS. As a result of the investigations, it is concluded that the literature is insufficient in this area.

The aim of this study is to investigate the effects of pulmonary function, respiratory muscle strength and trunk control on functional mobility in individuals with MS and compare with healthy individuals.


Eligibility criteria: Inclusion Criteria:

* 18-65 years old
* Having a definite MS diagnosis
* Up to 5.5 points on the Scored Disability Status Scale (EDSS)
* In the last 3 months have not experienced an attack
* Mini mental test score of 24 and above
* Acceptance to participate in the study.

Exclusion Criteria:

* Having orthopedic problems
* The presence of other neurological problems

Primary outcomes:
measure: 2 Minutes Walking Test
timeFrame: baseline
measure: Timed Up and Go Test
timeFrame: baseline
Secondary outcomes:
measure: Respiratory Functions Test
timeFrame: baseline
measure: Respiratory Muscle Strength
timeFrame: baseline
measure: Trunk Impairment Scale
timeFrame: baseline
measure: Side Bridge Test (core muscles endurance)
timeFrame: baseline
measure: Modified Biering-Sorensen test (core muscles endurance)
timeFrame: baseline
measure: Trunk Flexion Test (core muscles endurance)
timeFrame: baseline
measure: Prone bridge test (core muscles endurance)
timeFrame: baseline
measure: Sit-ups Test (core muscles power)
timeFrame: baseline
measure: Modified Push-ups Test (core muscles power)
timeFrame: baseline
measure: Lumbopelvic Stability Test
timeFrame: baseline
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
Study officials:
affiliation: Hacettepe University
name: MELIKE S CENGİZ
role: PRINCIPAL_INVESTIGATOR
References:
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