Clinical trial NCT05350995: Evaluation of Antibiotherapy Prescribed for Outpatients From Emergency Departments
Official title: Evaluation of Antibiotherapy Prescribed for Outpatients From Emergency Departments
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Infectious Disease
Emergencies
Lead sponsor: Henri Mondor University Hospital
Sponsor class: OTHER
First posted: 2022-04-28
Enrollment: 9600
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All major outpatients visiting an emergency department on one of the survey days.

Brief summary: French health insurance data indicate that approximately 15% of ambulatory antibiotic consumption is generated by hospital prescriptions. This extra-hospital consumption represents a greater volume than intra-hospital consumption. To date, hospital indicators of good antibiotic use do not include this outpatient dimension. This study will provide a snapshot of the proportion of ambulatory antibiotics generated by emergencies and analyze compliance with management recommendations.This study will serve as a basis for developing indicators of outpatient antibiotic consumption generated by hospital activity and for identifying specific intervention targets aimed at the misuse situations that have been highlighted.

This study will be carried out in the form of a repeated survey on a given day (4 days, one across each season), carried out by the local mobile antibiotic therapy team, using a standardized grid. The survey will concern all the medical records of the patients visiting any emergency department on the days of the survey.

The evaluation of antibiotic therapies prescribed in discharge orders will be carried out in accordance with local management recommendations by the site investigator (infectious disease and/or emergency medicine specialist), who will assess whether the prescription is in accordance with the recommendations or not.


Eligibility criteria: Inclusion Criteria:

* Visit on emergency department on one of the survey days
* Age ≥18

Exclusion Criteria:

* Patient opposed to the collection of his/her data
* Patient under guardianship or curatorship

Primary outcomes:
measure: Adequacy to local or national recommendations of antibiotic prescriptions identified on patient discharge prescriptions after a visit in emergency departments.
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
measure: Adequacy to the local or national recommendations of the antibiotic prescriptions identified on the patient discharge prescriptions by diagnosis.
timeFrame: Through study completion, an average of 1 year
measure: Antibiotics prescription rate at discharge from emergency department.
timeFrame: Through study completion, an average of 1 year
measure: Critical antibiotics prescription rate at discharge from emergency department.
timeFrame: Through study completion, an average of 1 year
measure: Factors associated with inadequacy to the local or national recommendations.
timeFrame: Through study completion, an average of 1 year
Other outcomes:
Locations:
city: Créteil
country: France
facility: CHU Henri Mondor
Study officials:
affiliation: Henri Mondor University Hospital
name: Clément Ourghanlian, PharmD
role: PRINCIPAL_INVESTIGATOR
References: