Clinical trial NCT05384795: Perioperative Atelectasis in Orthopaedic Surgery: a Prospective Study
Official title: Perioperative Atelectasis in Patients Undergoing Orthopaedic Surgery: Prospective Cohort Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Atelectasis
Lead sponsor: Centre Hospitalier Universitaire Vaudois
Sponsor class: OTHER
First posted: 2022-05-20
Enrollment: 141
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Participants will be patients scheduled for elective surgery at the Orthopedic Hospital from CHUV.

Brief summary: This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Detailed description: Atelectasis is one of the most common pulmonary complications in the perioperative period, occurring in 85% to 90% of patients under general anesthesia. It can be responsible for hypoxemia and be associated with postoperative pulmonary complications such as pneumonia. The consequences are a prolongation of the hospital stay and an increase in mortality.

The appearance of perioperative atelectasis is mainly secondary to the induction of general anesthesia with an incidence up to 90%. The different causes are, for example, the administration of muscle relaxants, mechanical ventilation and the position of the patient.

In orthopedic surgery, many procedures are performed under spinal anesthesia or under peripheral nerve block. At present, there are no studies measuring the incidence of atelectasis in patients operated under these two techniques of locoregional anesthesia, with the exception of parturients undergoing cesarean section.

This study aims at comparing a perioperative pulmonary atelectasis score, measured by pulmonary ultrasound, in patients operated undergoing orthopedic surgery under general anesthesia, spinal anesthesia or peripheral nerve block. The association between the atelectasis score and previously identified risk factors will be studied.

Eligibility criteria: Inclusion Criteria:

* Patients over the age of 18;
* Patients scheduled for an elective operation at the Orthopedic Hospital of CHUV;
* Signature of the study consent

Exclusion Criteria:

* Thoracic deformities preventing the performance of pulmonary ultrasound (dressings, drains, fractures, etc.);
* Refusal to participate;
* Patient does not speak French.
* Inability to discern

Primary outcomes:
measure: Lung atelectasis score
timeFrame: immediately after the surgery
Secondary outcomes:
measure: Lung atelectasis score
timeFrame: Four timepoints: at baseline, immediatly before surgery (after anesthesia induction), immediately after the surgery, and at the recovery room
Other outcomes:
Locations:
city: Lausanne
country: Switzerland
facility: Centre Hospitalier Universitaire Vaudois
state: Vaud
Study officials:
References: