Clinical trial NCT04298294: Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant
Official title: The Effect of Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant in the Esthetic Zone
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Bone Loss
Lead sponsor: Ain Shams University
Sponsor class: OTHER
First posted: 2020-03-06
Enrollment: 16
Sex: ALL
Minimum age (years): 20
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Group I (study group)8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with i-PRF\& bone graft

Group II (control group) 8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with bone graft
Primary purpose: OTHER

Brief summary: The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone

Detailed description: Grouping the samples: (sixteen patients was recruited from the outpatient clinic of Oral Medicine, Periodontology, Diagnosis and Radiology Department, Faculty of Dentistry, Ain Shams University).

The sixteen patients assigned to group 1 or group 2 will be randomly allocated using flip of a coin into one of the 2 treatment modalities.

Primary objective:

Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.

Secondary objective:

Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant.

Eligibility criteria: Inclusion Criteria:

* Healthy adult patient.
* Age from 20-50 years old
* Patients must be free of any systemic disease which could influence the surgical procedure.
* Tooth involved in the esthetic zone.
* Sufficient hard and soft tissue volume in vertical and buccolingual 6. Natural teeth adjacent to the involved tooth were required to be free from infection.
* Controlled oral hygiene.
* Indication for tooth extraction included;

  * Endodontic failures
  * Untreatable caries\> Non- restorable teeth
  * Vertical root fracture
  * Remaining roots
* The decision to proceed with the implant placement was made after tooth extraction and probing of the extraction socket which revealed:

  * The presence of intact facial bone.
  * Compliance with all requirements in the study and signing the informed consent.

Exclusion Criteria:

* Patient had surgeries in the same site during the last 6 months prior to the surgery.
* Severe vertical bone loss (socket type lll or type lV).
* Presence of acute dento-alveolar infection or periodontal affected of involved tooth.
* Pregnant and lactating females.
* Smokers.

Primary outcomes:
measure: Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.
timeFrame: 6 months follow up
measure: Radiographic analysis
timeFrame: 6 months follow up
measure: Radiographic analysis
timeFrame: 6 months follow up
Secondary outcomes:
measure: Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant
timeFrame: 6 months follow up
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Bassant Mohye
Study officials:
References: