Clinical trial NCT04887181: The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
Official title: The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dentin Hypersensitivity
Keywords: Dentin Hypersensitivity
Desensitizing Agent
Adhesive Resin
Lead sponsor: Kırıkkale University
Sponsor class: OTHER
First posted: 2021-05-14
Enrollment: 69
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.

Detailed description: This in-vivo study was done among 69 participants who reported at least one sensitivite tooth(Schiff Sensitivity Score \>1) as a result of the clinical examination. Participants were randomly divided into three treatment groups(n=23):

I. Tetracalcium phosphate and dicalcium phosphate containing desensitizer (Teethmate Desensitizer) II. %35 hydroxyethyl methacrylate and %5 glutaraldehyde containing desensitizer (Gluma Desensitizer) III. Self-etch adhesive resin (Hybrid Bond) These materials used in treatment of dentin hypersensitivity in 6 months clinical follow-up and the effects on the quality of life of individuals were evaluated with Dentine Hypersensitivity Experience Questionnaire (DHEQ).

Eligibility criteria: Inclusion Criteria:

* Not having any systemic disease,
* 18 years and older,
* At least one tooth complaining of dentin hypersensitivity (Schiff score\> 1),
* The acceptance of the volunteers participating in the research.

Exclusion Criteria:

* Active periodontal disease,
* Periodontal surgery for the last 3 months,
* Use of desensitizing toothpaste or mouthwash in the last 3 months,
* Long-term use of analgesic and anti-inflammatory drugs,
* Having a history of allergies,
* Women during pregnancy or breastfeeding,
* Parafunctional habits (bruxism, teeth grinding etc.),
* The presence of caries, pulpitis or restoration in teeth,
* Tooth tissue loss due to erosion, abrasion and abfraction,
* Congenital anomalies,
* Cracked teeth were not included in the study.

Primary outcomes:
measure: Schiff Cold Air Sensitivity Scale Scores
timeFrame: Before treatment, immediately after treatment, 1 week, 1 month, 3 month and 6 month
measure: Visual Analog Scale(VAS) Scores
timeFrame: Before treatment, immediately after treatment, 1 week, 1 month, 3 month and 6 month
measure: Dentin Hypersensitivity Experience Questionnaire (DHEQ) scores
timeFrame: Change from baseline quality of life at 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Kırıkkale
country: Turkey
facility: Kırıkkale University Faculty of Dentistry, Department of Restorative Dentistry
state: Yahşihan/Kırıkkale
Study officials:
affiliation: Kırıkkale University Faculty of Dentistry
name: Behiye Esra Özdemir, Res. Assist.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mason S, Burnett GR, Patel N, Patil A, Maclure R. Impact of toothpaste on oral health-related quality of life in people with dentine hypersensitivity. BMC Oral Health. 2019 Oct 22;19(1):226. doi: 10.1186/s12903-019-0919-x.