Clinical trial NCT06392412: Virtual Reality Cognitive Training for Older Adults With Mild Cognitive Impairment
Official title: Effects of Fully Immersive Virtual Reality Cognitive Training Based on Instrumental Activities of Daily Living for Older Adults With Mild Cognitive Impairment
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Mild Cognitive Impairment
Older Adults
Lead sponsor: Da-Yeh University
Sponsor class: OTHER
First posted: 2024-04-30
Enrollment: 52
Sex: ALL
Minimum age (years): 65
Maximum age (years): 90
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study aims to (1) develop and assess the feasibility of a fi-VRCT program based on IADL for older adults with MCI, (2) implement and evaluate the effectiveness of the fi-VRCT program based on IADL in older adults with MCI, and (3) investigate the potential mechanism of the fi-VRCT program based on IADL for older adults with MCI and refine this intervention accordingly.

Detailed description: As research on cognitive training methods for older adults with mild cognitive impairment (MCI) progresses, fully immersive virtual reality cognitive training (fi-VRCT) has emerged as a promising approach. While the benefits of fi-VRCT for enhancing cognitive function have been recognized, its potential to improve instrumental activities of daily living (IADL) and promote independence remains uncertain. This study addresses these questions by developing and validating a fi-VRCT program based on IADL to enhance cognitive and IADL performance among older adults with MCI.

Eligibility criteria: Inclusion Criteria:

1. Aged 65 or above.
2. MoCA score between 18 and 25.
3. Capability to follow directions and do tasks.

Exclusion Criteria:

1. History of dementia.
2. Previous neurodegenerative illness diagnosis.
3. Severe medical or surgical problems.
4. Major psychological disorders.
5. Inability to use VR system

Primary outcomes:
measure: Changes scores of Montreal Cognitive Assessment (MoCA)
timeFrame: At baseline, at week 9, and at 3-month follow-up.
measure: Change scores of Wechsler Memory Scale (WMS)
timeFrame: At baseline, at week 9, and at 3-month follow-up.
measure: Change scores of Amsterdam Instrumental Activities of Daily Living Questionnaire, Short Version
timeFrame: At baseline, at week 9, and at 3-month follow-up.
measure: Change scores of Lawton Instrumental Activities of Daily Living
timeFrame: At baseline, at week 9, and at 3-month follow-up.
Secondary outcomes:
measure: Change scores of Digit Span
timeFrame: At baseline, at week 9, and at 3-month follow-up.
measure: Change scores of Stroop Color-Word Test
timeFrame: At baseline, at week 9, and at 3-month follow-up.
Other outcomes:
measure: Presence Questionnaire
timeFrame: The initial, second, fifth, ninth, thirteenth, and final intervention sessions.
measure: Immersive Tendencies Questionnaire
timeFrame: The initial, second, fifth, ninth, thirteenth, and final intervention sessions.
measure: Simulator Sickness Questionnaire
timeFrame: The initial, second, fifth, ninth, thirteenth, and final intervention sessions.
measure: Technology Acceptance
timeFrame: The initial, second, fifth, ninth, thirteenth, and final intervention sessions.
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