Clinical trial NCT02900612: Effects of Two Aquatic Training Models in Physiological Parameters of Elderly Dyslipidemic Women.
Official title: Effects of Two Aquatic Training Models in Physiological Parameters of Elderly Dyslipidemic Women: a Randomized Controlled Clinical Trial.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dyslipidemias
Keywords: dyslipidemias,
aging
water aerobics training
resistance aquatic training
lipid profile
Lead sponsor: Hospital de Clinicas de Porto Alegre
Sponsor class: OTHER
First posted: 2016-09-14
Enrollment: 45
Sex: FEMALE
Minimum age (years): 60
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study aims to compare the effects of two water-based training models in physiological parameters of dyslipidemic elderly women. Thus, a randomized controlled clinical trial will be conducted in parallel with the participation of 45 dyslipidemic elderly women.

Detailed description: The women will be randomly divided into three groups: water aerobics training (WA), resistance aquatic training (WR) and the third is the control group (who will perform relaxation sessions under water). The three groups will attend classes during 10 weeks, with two weekly sessions of 45 minutes each. The WA and WR groups will use the same four exercises in their training.

The WA group will be trained using the interval method, performing six blocks of five minutes each one, alternating four minutes at intensities corresponding to 90 to 100% of the heart rate corresponding to the second ventilatory threshold (HRVT2) and one minute at intensities between 80 and 90% HRVT2.

The WR group will perform four to eight sets of 20 to 10 seconds along the macrocycle, always at maximal speed execution of the exercises.

Will be measured, before and after the period of 10 weeks of intervention, biochemical, cardiorespiratory, neuromuscular and hemodynamic variables, parameters of quality of life and depressive symptoms in addition to the cardiovascular risk score of the participants of the three groups.

Data will be described by means values and lower and upper limits, with a 95% confidence interval. Comparisons between and within groups were performed using the method of generalized estimates of equations (GEE), with Bonferroni post hoc, adopting a 0.05 significance level.

Eligibility criteria: Inclusion Criteria:

* being female, aged between 60 and 75, sedentary (not practicing any kind of regular, supervised physical activity in the last three months), have any type of dyslipidemia.

Exclusion Criteria:

* women who are smokers, suffering from cardiovascular disease with associated complications and those with orthopedic diseases that prevented the practice of systematic physical exercise, users of hormone therapy drugs and lipid-lowering medications.

Primary outcomes:
measure: Total Cholesterol (TC) Change
timeFrame: Change from baseline total cholesterol at 10 weeks
Secondary outcomes:
measure: Triglycerides (TG) Change
timeFrame: Change from baseline triglycerides at 10 weeks
measure: High Density Lipoprotein (HDL) Change
timeFrame: Change from baseline HDL at 10 weeks
measure: C-Reactive Protein (CRP) Change
timeFrame: Change from baseline C-reactive protein at 10 weeks
measure: Low Density Lipoprotein (LDL) Change
timeFrame: Change from baseline LDL at 10 weeks
measure: Total Cholesterol/High Density Lipoprotein Ratio (TC/HDL ratio) Change
timeFrame: Change from baseline TC/HDL at 10 weeks
measure: Peak Oxygen Consumption (VO2peak) Change
timeFrame: Change from baseline VO2peak at 10 weeks
measure: Oxygen Consumption at anaerobic threshold (VO2VT2) Change
timeFrame: Change from baseline VO2VT2 at 10 weeks
measure: Heart Rate at anaerobic threshold (HRVT2) Change
timeFrame: Change from baseline HRVT2 at 10 weeks
measure: Rest Heart Rate (HRrest) Change
timeFrame: Change from baseline HRrest at 10 weeks
measure: Lipoprotein Lipase (LPL) Change
timeFrame: Change from baseline LPL at 10 weeks
measure: Maximal dynamic muscle strength of knees extensors (MSKE) Change
timeFrame: Change from baseline MSKE at 10 weeks
measure: Maximal dynamic muscle strength of knees flexors (MSKF) Change
timeFrame: Change from baseline MSKF at 10 weeks
measure: Maximal dynamic muscle strength of horizontal shoulder flexors (MSHSF) Change
timeFrame: Change from baseline MSHSF at 10 weeks
measure: Rest Cardiac Output (COrest) Change
timeFrame: Change from baseline COrest at 10 weeks
measure: Rest Stroke Volume (SVrest) Change
timeFrame: Change from baseline SVrest at 10 weeks
measure: Peak Cardiac Output (COpeak) Change
timeFrame: Change from baseline COpeak at 10 weeks
measure: Peak Stroke Volume (SVpeak) Change
timeFrame: Change from baseline SVpeak at 10 weeks
measure: Rest Arterial Systolic Blood Pressure (SBPrest) Change
timeFrame: Change from baseline SBPrest at 10 weeks
measure: Rest Arterial Diastolic Blood Pressure (DBPrest) Change
timeFrame: Change from baseline DBPrest at 10 weeks
measure: Cardiovascular Risk Score (CRS) Change
timeFrame: Change from baseline cardiovascular risk score at 10 weeks
measure: Quality of Life Change
timeFrame: Change from baseline quality of life at 10 weeks
Other outcomes:
Locations:
Study officials:
affiliation: Hospital de Clinicas de Porto Alegre
name: Ricardo Stein
role: PRINCIPAL_INVESTIGATOR
References: