Clinical trial NCT05853562: Effects of Structured Exercise Program in Bilateral Vestibular Hypofunction
Official title: Effects of Structured Exercise Program on Severity of Dizziness, Kinesiophobia, Balance, Fatigue, Quality of Sleep, Activities of Daily Living and Quality Of Life in Bilateral Vestibular Hypofunction
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Bilateral Vestibular Hypofunction
Keywords: Bilateral Vestibular Hypofunction
Dizziness
Kinesiophobia
Balance
Quality of Sleep
Quality of Life
Structured Exercise
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2023-05-10
Enrollment: 20
Sex: ALL
Minimum age (years): 20
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Background: The vestibular rehabilitation is an exercise-based method, aiming to maximize central nervous system(CNS) compensation at vestibular nuclear and other CNS levels for vestibular pathology. A minimal number of studies have documented the impact of Vestibular rehabilitation on the recovery rate of patients with Bilateral Vestibular Hypofunction(BVH).

Objective: The purpose of this study was to investigate the effectiveness of structured vestibular rehabilitation (VR) programs on severity of dizziness, kinesiophobia, balance, fatigue, quality of sleep, activities of daily living( ADL) and quality of life(QoL) in subjects with chronic BVH.

Method: Twenty-five participants diagnosed with BVH were included in the study. A structured VR program was applied in 50-minute sessions once a week and as a home exercise program 3 days a week over 8 weeks. Participants were evaluated for severity of dizziness with the Visual Analog Scale (VAS), for kinesiophobia with the Tampa Scale of Kinesiophobia (TSK), for balance with the Semitandem, tandem, and standing tests, for quality of sleep with the Pittsburgh Sleep Quality Index (PSQI), for ADL with the Vestibular Disorders Activities of Daily Life (VADL), for QoL with Dizziness Handicap Inventory (DHI) and for fatigue with the Fatigue Severity Scale (FSS) at the baseline (T0), at 4th week (T1), 8th week (T2), and 20th week (T3) after study started.


Eligibility criteria: Inclusion Criteria:

* Being between 20-80 years old
* Diagnosed with bilateral peripheral vestibular hypofunction by videonystagmography
* Have symptoms for more than three months from onset of illness

Exclusion Criteria:

* having no symptoms of bilateral peripheral vestibular hypofunction
* having Meniere's disease, vestibular migraine and other undulating vestibular disorders, cognitive, visual, neurological or general motor impairment
* having previously received vestibular rehabilitation

Primary outcomes:
measure: Visual Analog Scale
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
measure: Tampa Scale of Kinesiophobia
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
measure: Semitandem, Tandem, and Standing tests
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
measure: Pittsburgh Sleep Quality Index
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
measure: Dizziness Handicap Inventory
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
measure: Fatigue Severity Scale
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
measure: Vestibular Disorders Activities of Daily Life
timeFrame: Change from Baseline Systolic Blood Pressure at 4 / 8 / 12 / 16 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medipol University
state: Beykoz
Study officials:
References: