Clinical trial NCT05420194: Assessment of Postural Stability in Patients With Total Knee Arthroplasty
Official title: Assessment of Postural Stability in Patients With Total Knee Arthroplasty
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Knee Arthritis
Arthroplasty Complications
Obesity
Balance; Distorted
Lead sponsor: Acibadem University
Sponsor class: OTHER
Collaborators: name: Marmara University
First posted: 2022-06-15
Enrollment: 80
Sex: ALL
Minimum age (years): 45
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who had undergone total knee arthroplasty

Brief summary: Postural balance can be described as the integration of the information obtained from visual, vestibular and somatosensory systems. Postural stability is achieved by sensory information about the static or dynamic position of the body resulting in an appropriate motor response. Poor postural stability in individuals with knee osteoarthritis often results in an increased risk of falling and decrease in mobility. It has been reported that 40% of knee osteoarthritis patients fall at least once in a year. Total knee arthroplasty (TKA) is a surgical treatment approach applied to individuals with advanced knee osteoarthritis. It has been shown that this method provides an improvement in the postural stability levels of individuals compared to the preoperative period and a decrease in number of falls reported by the patient. Even if this improvement is achieved, postural stability losses can still be observed in individuals undergoing TKA which affect balance performance.

Obesity is defined by an excessive increase in the ratio of body fat mass relative to lean mass. Individuals with a Body Mass Index (BMI) above 30 kg/m2 are defined as obese. Changes in body composition and increased adiposity rate lead to significant locomotor system problems. A decrease in postural control, increased risk of falling or fear of falling can be defined as locomotor system problems. It has been reported that there is a relationship between increased fat ratio and loss of postural stability in adult obese individuals.

In a published study, it was reported that as of 2029, 46% of the population in America will be obese or morbidly obese, and 69% of individuals who have undergone total knee arthroplasty surgery will be obese or morbidly obese. Obesity causes several complications such as increased mortality and increase in likelihood of revision surgery that can be seen after total knee arthroplasty. Therefore, it is clinically important to determine the functional status and balance status in order to reduce the possible long-term complications that may develop in the post-operative period and the risk of falling, especially in obese individuals.

The effects of increasing obesity level on postural stability in individuals undergoing total knee arthroplasty are unknown. In this context, the aim of our study is to compare the postural stability levels of normal, overweight and obese individuals who underwent total knee arthroplasty.


Eligibility criteria: Inclusion Criteria:

* Follow-up period is between 1-5 years,
* Volunteer to participate in the study,

Exclusion Criteria:

* Having undergone revision surgery on the same or opposite knee after total knee arthroplasty,

  - Presence of vertigo or another neurological disease,
* Patients who have undergone total hip replacement.

Primary outcomes:
measure: Postural Stability
timeFrame: Day 1
measure: Falls Efficacy Scale
timeFrame: Day 1
Secondary outcomes:
measure: Short Physical Performance Battery (SPPB)
timeFrame: Day 1
measure: Timed Up and Go Test
timeFrame: Day 1
measure: Pain Severity
timeFrame: Day 1
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Acıbadem University
city: İstanbul
country: Turkey
facility: Marmara University
Study officials:
References: