Clinical trial NCT07015814: Comparative Evaluation of Glycemic Index of Different Types of Jaggery Produced Locally in Pakistan
Official title: Comparative Evaluation of Glycemic Index of Different Types of Jaggery Produced Locally in Pakistan
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Glycemic Index and Glycemic Load
Keywords: glycemic index
Lead sponsor: Rehman Medical Institute - RMI
Sponsor class: OTHER
First posted: 2025-06-11
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response.

Detailed description: This study aims to evaluate and compare the glycemic index (GI) of various types of jaggery by measuring their effect on blood glucose levels in healthy individuals. Using glucose as the reference standard , the objective is to determine how different jaggery types influence postprandial blood sugar response. The findings will help identify which types of jaggery have lower glycemic impact, contributing to better dietary choices for glycemic control.

Eligibility criteria: Inclusion Criteria:Participants should be clinically healthy, as determined by their medical records and verbal history. Only individuals with normal fasting blood glucose levels (70-99 mg/dL) during screening will be eligible -

Exclusion Criteria:1) Participants must not have any chronic disease, not be taking any medications that influence carbohydrate metabolism (such as corticosteroids or metformin), and should be non-smokers and non-alcoholics.

2) Pregnant or lactating female participants, as well as any person with gastrointestinal, metabolic, or endocrine disease (e.g., thyroid disease, PCOS, IBD), will be excluded.

3) Also, subjects with a history of recent acute illness (within the last 2 weeks) will be deferred.

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Primary outcomes:
measure: Glycemic Index (GI) of Different Types of Jaggery
timeFrame: Measured at multiple time points post-consumption (e.g., 0, 15, 30, 45, 60, 90, and 120 minutes) during each test session.
Secondary outcomes:
measure: Postprandial Blood Glucose Response Curve
timeFrame: Same as primary outcome (0-120 minutes).
Other outcomes:
Locations:
city: Peshawar
country: Pakistan
facility: Rehman Medical Institue
state: KP
Study officials:
References:
citation: Fats and oils in human nutrition. Report of a joint expert consultation. Food and Agriculture Organization of the United Nations and the World Health Organization. FAO Food Nutr Pap. 1994;57:i-xix, 1-147. No abstract available.
citation: International Diabetes Federation. (2021). *IDF Diabetes Atlas* (10th ed.). Brussels, Belgium: IDF.
citation: Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, Bowling AC, Newman HC, Jenkins AL, Goff DV. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981 Mar;34(3):362-6. doi: 10.1093/ajcn/34.3.362.