Clinical trial NCT05993208: Correlation Between OCT and mFERG Findings With VA After Vitrectomy Surgery for Retinal Detachment
Official title: Correlation Between Optical Coherence Tomography and Multifocal Electroretinogram Findings With Visual Acuity After Vitrectomy Surgery for Retinal Detachment
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Retinal Detachment
Lead sponsor: New Valley University
Sponsor class: OTHER
Collaborators: name: Assiut University
First posted: 2023-08-15
Enrollment: 40
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Retrospective observation (analytic) study

Brief summary: Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity after vitrectomy surgery for Retinal detachment.

Detailed description: Although the anatomical success rate of vitreoretinal surgery has improved over the last decade, visual results remain compromised? Patients with macula-off retinal detachments (RDs) can have poor visual recovery, specific color vision defects, or metamorphopsia postoperatively despite successful retinal reattachment. In these cases, subtle changes in the foveal structure may be causing visual disturbances that can be difficult to identify during standard clinical examinations such as slit lamp biomicroscopy or binocular indirect ophthalmoscopy .reported a possible association between incomplete visual recovery and the presence of residual subretinal fluid (SRF) postoperatively.

Optical coherence tomography (OCT) is a non-invasive technique that provides information about the morphology of the retina, and especially of the macular area in vivo. Some studies support the idea that OCT determines structural changes in the macula that are correlated with subjective visual function, including visual acuity (VA) in patients with vitrectomy for retinal detachment. Additionally, multifocal electroretinogram (m fERG) evaluation can be helpful in assessing macular function in post-vitrectomy. However, to date, there are relatively few reports concerning the combined use of OCT and m fERG for the correlation between retinal morphology and function of the macula in patients with vitrectomy for retinal detachment surgery. The purpose of our study is to determine whether a significant correlation exists between the amplitude of m fERG, visual acuity, and the morphological OCT changes by in the macula after vitrectomy for retinal detachment

Eligibility criteria: Inclusion Criteria:

* patients with successful vitrectomy for retinal detachment.

Exclusion Criteria:

* The patients who had vitrectomy for reasons other than retinal detachment surgery
* Patients who had done scleral buckle surgery
* Patients with media opacity are prevented from doing retina imaging.
* Failed or recurrent vitrectomy surgery

Primary outcomes:
measure: CMT,BCVAand mf-ERG were recoreded in 40 eyes of 40 patintes with vitrectomy for retinal detchament surgery .
timeFrame: 6 months
measure: BCVA(best corrected visual acuity)
timeFrame: 6 Month
measure: CMT(central macualr thikness ) um
timeFrame: 6 month
measure: mf-ERG amplituide nV/deg2
timeFrame: 6 month
Secondary outcomes:
Other outcomes:
Locations:
city: Sohag
country: Egypt
facility: New Vally University
Study officials:
References: