Clinical trial NCT03661073: Motor Imagery Ability After Stroke
Official title: Comprehensive Assessment of Motor Imagery Ability After Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2018-09-07
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: Individuals with stroke may experience sensory-motor deficit and/or neglect, with possible reduction in motor imagery ability (MI). To our knowledge, no study completely investigated MI ability in one individual whereas MI practice can be performed using visual or kinesthetic modalities (respectively visualizing with mind's eyes or imagining movement using sensation) and internal or external perspectives (performing action as spectator or as actor). This study aims to investigate MI ability in patients with stroke as compared to aged-matched healthy individuals. The investigators will assess explicit MI ability using 3 questionnaires (Movement Imagery Questionnaire-RS - MIQ-RS, Kinesthetic and Visual Imagery Questionnaire-20 - KVIQ-20, Vividness of Movement Imagery Questionnaire-2 - VMIQ-2) and 2 tests (imagined Time Up and Go - iTUG, imagined Box and Block test - iBBT). Outcome parameters will be i) the composite score of vividness measured for all tests using Likert scales, ii) the temporal equivalence between MI and Physical practice (PP - where MI/PP ratio equal to 1 indicate good MI ability and respect of temporal equivalence between MI and PP) and iii) the amplitude of electrodermal activity. The investigators will also study implicit MI ability using a hand laterality judgment task. Outcomes parameters will be response time (i.e. the duration to identify the hand laterality) and the percentage of correct responses.


Eligibility criteria: Inclusion Criteria:

For both groups:

* be more than 18 years old
* be less than 75 years old
* benefit from social security

For experimental group:

* patient admitted in Henry Gabrielle hospital for rehabilitation
* patient with one single episode of stroke

Exclusion Criteria:

For patients:

* sign of cognitive decline (MMSE score under 27/30)
* evolutionary pathology associated

For healthy subjects:

- neurological or orthopaedical history

Primary outcomes:
measure: Score of vividness
timeFrame: Day 1
Secondary outcomes:
measure: Temporal equivalence measured during KVIQ-20
timeFrame: Day 1
measure: Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during KVIQ-20.
timeFrame: Day 1
measure: Score of vividness measured during VMIQ -2
timeFrame: Day 1
measure: Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during VMIQ -2.
timeFrame: Day 1
measure: Score of vividness measured during MIQ-RS.
timeFrame: Day 3
measure: Temporal equivalence measured during MIQ-RS.
timeFrame: Day 3
measure: Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during MIQ-RS.
timeFrame: Day 3
measure: Percentage of correct response to identify the hand laterality during the implicit motor imagery ability assessment
timeFrame: Day 3
measure: Response time to identify the hand laterality during the implicit motor imagery ability assessment
timeFrame: Day 3
measure: Score of vividness measured during iTUG.
timeFrame: Day 5
measure: Temporal equivalence measured during iTUG.
timeFrame: Day 5
measure: Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during iTUG.
timeFrame: Day 5
measure: Score of vividness measured during iBBT.
timeFrame: Day 5
measure: Temporal equivalence measured during iBBT.
timeFrame: Day 5
measure: Amplitude of electrodermal responses that will be measured during imagined movement with reference to actual movements measured during iBBT.
timeFrame: Day 5
Other outcomes:
Locations:
city: Saint-Genis-Laval
country: France
facility: Hôpital Henry Gabrielle
Study officials:
References: