Clinical trial NCT06845150: Combined Compared to Sequential Cognitive and Physical Training in Anterior Cruciate Ligament Reconstructed Individuals
Official title: Dual-Task Training in an Immersive Environment Compared to Single Task Training in Anterior Cruciate Ligament Reconstructed Individuals
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Anterior Cruciate Ligament Reconstruction Rehabilitation
Keywords: motor-cognitive training
dual-task training
anterior cruciate ligament injury
return to competition
Lead sponsor: Zurich University of Applied Sciences
Sponsor class: OTHER
Collaborators: name: Kantonsspital Winterthur KSW
name: ZHAW DIZH Fellowship Program
First posted: 2025-02-25
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The goal of this clinical trial is to investigate changes in cognitive and physical performance after 10 weeks of dual or single task training in anterior cruciate ligament (ACL) reconstructed individuals. The main questions it aims to answer are:

* Does cognitive performance in ACL reconstructed individuals change after multiple training sessions incorporating single versus dual-task?
* Does physical performance and intrinsic motivation for training change over the course of 10 weeks when performing single versus dual-task training sessions?
* What movement patterns do ACL reconstructed individuals show during a dual-task training in an immersive environment?

Researchers will compare a combined dual-task training (combined physical and cognitive training) to a single task training (physical and cognitive training separately) to see if there are changes on cognitive performance depending on the training type.

Participants will:

* Perform dual-task or single task training twice per week for 10 weeks
* Visit the clinic before and after the training period for tests
* Visit the movement laboratory once for analysis of movement patterns


Eligibility criteria: Inclusion Criteria:

* 18-40 years old
* At least 6 months after ACL injury
* Surgically reconstructed ACL
* At least 2 hours of sports participation before the injury
* Written consent of the attending surgeon to perform intensified training methods including one-legged jumps at 6 months after surgery after the first visit
* Ability to give informed consent as documented by signature
* Ability to understand instructions in German or English
* BMI \< 28 kg/m\^2
* Availability to take part in at least 70% of all training sessions

Exclusion Criteria:

* Surgery on the contralateral leg during the last 12 months
* Acute or chronic musculoskeletal, neurological, or cardiopulmonary disorders
* Unadjusted vision problems
* Concussion during the last 6 months
* Pregnancy
* Breastfeeding
* Amputation
* Inflammatory pain or swelling during exercising

Primary outcomes:
measure: Interference
timeFrame: Baseline, after 5 weeks of training, after 10 weeks of training
measure: Response inhibition
timeFrame: Baseline, after 5 weeks of training, after 10 weeks of training
Secondary outcomes:
measure: Jumping performance - contact time
timeFrame: Baseline and after 10 weeks of training
measure: Jumping performance - peak force
timeFrame: Baseline and after 10 weeks of training
measure: Strength
timeFrame: Baseline and after 10 weeks of training
measure: Intrinsic motivation
timeFrame: At the end of each training session (2x/week for 10 weeks)
measure: Kinematics and kinetics of the lower extremities
timeFrame: During dual-task training in an immersive environment
measure: Kinematics and kinetics of the lower extremities
timeFrame: Baseline and after 10 weeks of training
Other outcomes:
measure: Kujala
timeFrame: Baseline and after 10 weeks of training
measure: ACL-Return to Sport after Injury Scale
timeFrame: Baseline and after 10 weeks of training
measure: Tegner Activity Scale
timeFrame: Baseline and after 10 weeks of training
measure: Socio-demographic data
timeFrame: Baseline
measure: Subjective Cognitive Load
timeFrame: At the end of each training session (2x/week for 10 weeks)
Locations:
city: Winterthur
country: Switzerland
facility: KSW Kantonsspital Winterthur
city: Winterthur
country: Switzerland
facility: ZHAW Zurich University of Applied Sciences
Study officials:
References: