Clinical trial NCT04098614: Barriers to Substance Use Disorder Recovery
Official title: Barriers to Substance Use Disorder Recovery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Substance Use Disorders
Keywords: recovery coaching
risk factors
substance abuse
EEG
Lead sponsor: Prisma Health-Upstate
Sponsor class: OTHER
Collaborators: name: Clemson University
name: Medical University of South Carolina
First posted: 2019-09-23
Enrollment: 99
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The investigator/study personnel inform the participant regarding which arm they have been assigned and inform a recovery coach if the participant is randomized to the intervention arm.
Primary purpose: TREATMENT

Brief summary: The study purpose is to investigate how an inpatient recovery coaching intervention can overcome or mitigate specific risk factors and barriers to initiating and maintaining Substance Use Disorder recovery. This study will offer insight into how and why an inpatient link to recovery coaching is effective for promoting long-term Substance Use Disorder recovery.

Detailed description: Substance Use Disorder (SUD) is a prevalent disease that impacts an estimated 24 million Americans each year. The life-altering consequences of SUD are both diverse and severe, influencing mortality, the workplace, and economics. The goal of this study is to determine how specific risk factors of relapse and barriers to recovery, including neurocognitive, health, personal, social, financial, and situational barriers, can be overcome or changed through a recovery coaching intervention. This work seeks to provide a mechanism to demonstrate exactly how and why this potential new model of care (recovery coaching) is effective, rather than simply assessing if it can work. To accomplish this aim, the change between baseline and 6-month assessments will be assessed. Then, the difference in the change between individuals assigned to the current standard of care and patients assigned to inpatient recovery will be compared.

Eligibility criteria: Inclusion Criteria:

* Age 18 - 60
* English speaking;
* Identified by healthcare provider as having Substance Use Disorder
* Recent substance use
* Currently admitted to the Medical Teaching Services, general medicine hospitalist services, or Infectious Disease Consult service at Greenville Memorial Hospital

Exclusion Criteria:

* Are unable to provide informed consent (intubation, confusion, etc.) during hospitalization
* Are admitted for marijuana use only
* Are admitted for cocaine use only
* Are pregnant

Primary outcomes:
measure: Change in Social Support
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
measure: Change in Financial Barriers to SUD Recovery
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
measure: Change in Situational Barriers to SUD Recovery
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
measure: Change in Inhibitory Control
timeFrame: baseline and 6 months post-baseline assessment
measure: Change in Resting State EEG beta poewer
timeFrame: baseline and 6 months post-baseline assessment
measure: Change in Striatal Dopaminergic Functioning
timeFrame: baseline and 6 months post-baseline assessment
measure: Change in Risk-Taking
timeFrame: baseline and 6 months post-baseline assessment
measure: Change in Emotion Regulation
timeFrame: baseline and 6 months post-baseline assessment
measure: Change in Goal-Related Activities
timeFrame: baseline and 6 months post-baseline assessment
Secondary outcomes:
measure: Engagement in Recovery Services
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
measure: Hospital Visit Frequency
timeFrame: six months pre- and post-baseline assessment
measure: Substance Use Severity
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
measure: Emotional Well-being
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
measure: Life Satisfaction
timeFrame: intervals of 1, 2, 3, and 6 months post-baseline assessment
Other outcomes:
Locations:
city: Greenville
country: United States
facility: Greenville Memorial Hospital
state: South Carolina
Study officials:
References:
citation: Cupp JA, Byrne KA, Herbert K, Roth PJ. Acute Care Utilization After Recovery Coaching Linkage During Substance-Related Inpatient Admission: Results of Two Randomized Controlled Trials. J Gen Intern Med. 2022 Aug;37(11):2768-2776. doi: 10.1007/s11606-021-07360-w. Epub 2022 Mar 16.