Clinical trial NCT03930160: LODS Role in Predicting 30-day Mortality Outcome in ICU
Official title: Logistic Organ Dysfunction System Role in Predicting 30-day Mortality Outcome in Intensive Care Unit of dr. Cipto Mangunkusumo General Hospital Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Mortality
Keywords: Intensive care unit
Logistic Organ Dysfunction System
30-day Mortality
Sepsis
Mortality prediction
Lead sponsor: Indonesia University
Sponsor class: OTHER
First posted: 2019-04-29
Enrollment: 439
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: intensive care unit patients medical records

Brief summary: LODS score for deceased ICU patients within 30 days is higher than survived ICU patients


Eligibility criteria: Inclusion Criteria:

* adult patient (age 18 years and above) admitted to ICU

Exclusion Criteria:

* patients admitted to ICU due to burn injury, coronary artery disease, post cardiac surgery
* patients with incomplete required information for LODS score
* patients deceased or discharged less than 24 hours of admission

Primary outcomes:
measure: LODS score discrimination ability
timeFrame: 30 days from admission
measure: LODS score calibration
timeFrame: 30 days from admission
measure: Correlation between LODS score variables with patient outcome
timeFrame: 30 days from admission
Secondary outcomes:
measure: Patient outcome
timeFrame: 30 days from admission
measure: LODS neurologic variable score: Glasgow Coma Scale (GCS)
timeFrame: Day 1
measure: LODS cardiovascular variable score: Heart rate (HR) and/or systolic blood pressure (SBP)
timeFrame: Day 1
measure: LODS renal variable score: serum urea nitrogen (BUN) and/or creatinine and/or urine output (UO)
timeFrame: Day 1
measure: LODS pulmonary variable score: Partial oxygen pressure (PaO2)/Fraction of inspired oxygen (FiO2) on Mechanical Ventilation (MV) or Continuous Positive Airway Pressure (CPAP)
timeFrame: Day 1
measure: LODS hematologic variable score: white blood cell (WBC) count and/or platelet count
timeFrame: Day 1
measure: LODS hepatic function variable score: Serum Bilirubin and/or Prothrombin time (PT)
timeFrame: Day 1
Other outcomes:
Locations:
city: Jakarta Pusat
country: Indonesia
facility: Rumah Sakit Cipto Mangunkusumo
state: DKI Jakarta
Study officials:
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