Clinical trial NCT05418595: Ultrasonographic Evaluation of Ovarian Stromal Vascularity in Women With Polycystic Ovary Syndrome (PCOS)
Official title: Ultrasonographic Evaluation of Ovarian Stroma in PCOS Women
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Ovarian Cysts
Lead sponsor: Usak State Hospital
Sponsor class: OTHER
First posted: 2022-06-14
Enrollment: 42
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 38
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Reproductive period, PCOS women

Brief summary: The most common endocrine condition in reproductive women is polycystic ovary syndrome. It has a prevalence of 5-10%. According to the Rotterdam criteria, oligo/anovulation, clinic or biochemical hyperandrogenism, PCOS morphology in ultrasonography, and the presence of these two criteria are required for diagnosis.

The echogenicity of the ovarian stroma, vascularity, ovarian size, cystic pattern density, and subcortical organization of cysts are all significant considerations in ultrasonographic evaluation.

Detailed description: Retrospective archive study.

In the years 2018-2019, the ultrasonographic archives of PCOS women will be analyzed retrospectively in the Radiology department of Usak Education and Research Hospital. Ultrasonographic (Two-dimensional ultrasonography , conventional and other doppler) measurements of ovaries will be assessed in ultrasonographic data. Patient's data ( Menstrual cycle, androgenic findings, age, BMI etc..) will be obtained on the hospital records, PCOS patient's phenotype will be evaluated according to National Institutes Health (NIH) recommendations.

The ovarian ultrasonographic findings of PCOS women will be compared.

This study approved by Usak University Medical Faculty Ethical Committee April,06,2022.

The Ethical Committee decision number is 57-57-04.

Eligibility criteria: Inclusion Criteria:

* Reproductive period According to Rotterdam criteria PCOS women.

Exclusion Criteria:

Women have not PCOS criteria, Non-reproductive period Pregnancy Postpartum Ovarian mass Underwent ovarian surgery.

Primary outcomes:
measure: The superiority of Superb microvascular imaging doppler technique over the conventional doppler techniques
timeFrame: 1 month
Secondary outcomes:
Other outcomes:
Locations:
city: Usak
country: Turkey
facility: İrem Şenyuva
Study officials:
affiliation: USAK TRAINING AND RESEARCH HOSPITAL, DEPARTMENT OF OBSTETRICS AND GYNECOLOGY,TURKEY
name: İrem Şenyuva, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Ozdemir O, Sari ME, Kalkan D, Koc EM, Ozdemir S, Atalay CR. Comprasion of ovarian stromal blood flow measured by color Doppler ultrasonography in polycystic ovary syndrome patients and healthy women with ultrasonographic evidence of polycystic. Gynecol Endocrinol. 2015 Apr;31(4):322-6. doi: 10.3109/09513590.2014.995617. Epub 2015 Jan 5.
citation: Makled AK, El Sherbiny M, Elkabarity R. Assessment of ovarian stromal blood flow after metformin treatment in women with polycystic ovary syndrome. Arch Gynecol Obstet. 2014 Apr;289(4):883-91. doi: 10.1007/s00404-013-3057-8. Epub 2013 Nov 7.