Clinical trial NCT00468572: Using Affectionate Communication as a Response to Acute Stress
Official title: Affectionate Communication as a Mechanism for Responding to Acute Stress
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stress
Keywords: Emotion
Oxytocin
Cortisol
Lead sponsor: Arizona State University
Sponsor class: OTHER
Collaborators: name: National Institute of Mental Health (NIMH)
First posted: 2007-05-02
Enrollment: 120
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: This study will examine the effects of tending to significant social relationships on managing and reducing stress.

Detailed description: Stress is a large part of daily modern life; however, it can cause a number of long-term problems for mental and physical health. Recent research has confirmed that there are definite mental and physical health benefits of maintaining significant positive social bonds. Many of these benefits appear to be associated with the ability to regulate stress that is caused by environmental challenges. Drawing on close relationships and expressing affection may help people to recover from stress more effectively. This study will evaluate the tend-and-befriend theory, which suggests that engaging in behaviors aimed at maintaining and strengthening significant social bonds can act as an adaptive response to acute stress.

All participants in this study will undergo a series of standard laboratory stressors designed to elevate cortisol levels. Cortisol, also known as the "stress hormone," is activated and secreted within the body in response to stress. Current research suggests that displaying signs of affection toward a loved one can lower cortisol levels, causing the body to relax and recover from a stressful situation more quickly. After lab tests have been completed, participants will be randomly assigned to an experimental or control group. Participants assigned to the experimental group will spend 20 minutes writing an affectionate letter to a loved one. Participants assigned to the control group will spend 20 minutes writing about meaningless topics. Levels of cortisol will be measured using saliva samples from each participant during the writing session. Levels of oxytocin, a hormone known to transmit signals within the brain and often associated with bonding and building trusting relationships, will be measured from blood samples taken during the writing session as well. Participants will also provide a self-report of their current stress level at the end of the study. Participation in this study will last approximately 2 hours. By examining associations between the communication of affection and responses to acute stress, this study may eventually lead to the development of new and better treatment options for people with constant acute stress.

Eligibility criteria: Inclusion Criteria:

* English-speaking
* Weigh at least 110 pounds
* Moderate to no anxiety about having blood drawn

Exclusion Criteria:

* Hypertension or diabetes
* Current or recent pregnancy
* Colorblindness
* History of cancer
* Current use of alpha blockers, beta blockers, or steroids

Primary outcomes:
measure: Oxytocin levels
timeFrame: Measured at Hour 2
measure: Cortisol levels
timeFrame: Measured at Hour 2
Secondary outcomes:
measure: Self-reported stress level
timeFrame: Measured at Hour 2
Other outcomes:
Locations:
city: Tempe
country: United States
facility: Exercise and Sports Research Institute
state: Arizona
Study officials:
affiliation: Arizona State University
name: Kory Floyd, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Floyd K, Mikkelson AC, Tafoya MA, Farinelli L, La Valley AG, Judd J, Haynes MT, Davis KL, Wilson J. Human affection exchange: XIII. Affectionate communication accelerates neuroendocrine stress recovery. Health Commun. 2007;22(2):123-32. doi: 10.1080/10410230701454015.