Clinical trial NCT03155360: Infants Colics : Towards a Migrainous Origin ?
Official title: Association Between Infant Colics and Parental Migraine ? Non Interventional Study in the Pediatric Emergency Unit of Nancy (France) University Hospital
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Colic, Infantile
Migraine
Migraine Equivalents
Keywords: Colics
infant colics
Migraine equivalent
Migraine
Episodic symptoms associated to migraine
Colic
Lead sponsor: Central Hospital, Nancy, France
Sponsor class: OTHER
First posted: 2017-05-16
Enrollment: 300
Sex: ALL
Minimum age (years): 60
Maximum age (years): 180
Standard ages: CHILD
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All infants between 60 days and 180 days of life who comes to the Nancy University Hospital pediatric emergency unit

Brief summary: According to recent studies, we want to find evidences that infant colics could be a episodic symptom associated to migraine as cyclic vomiting syndrome or abdominal migraine are. The main purpose is to compare the presence of colics in infants between 60 days and 180 days of life and the presence of migraine in their parents to determine if colicky children's parents are more migrainous than other parents.

Detailed description: Recent studies shows that :

* Infants with colics have more probability to become migrainous when they will grow up
* Migrainous children have more colic history in their past
* Migrainous parents have more babies with colics than non-migrainous parents

According to these studies, we want to find othen evidences that infant colics could be a migraine equivalent as cyclic vomiting syndrome or abdominal migraine are. Recently, the international classification of headache disease IIIbeta added in its appendix colics in the episodic symptoms associated to migraine

The main purpose of our study in the pediatric emergency unit of Nancy is to compare the presence of colics in infants and the presence of migraine in their parents to determine if colicky children's parents are more migrainous than other parents. The data collection will be made thanks to a survey which will be completed by the parents.

Eligibility criteria: Inclusion Criteria:

* All infants between 60 days and 180 days of life who comes to the Nancy University Hospital pediatric emergency unit

Exclusion Criteria:

* Language barrier of parents

Primary outcomes:
measure: Proportion of real colics according to Wessel definition
timeFrame: At the inclusion
measure: Proportion of migrainous parents
timeFrame: At the inclusion
Secondary outcomes:
measure: Proportion of Infant colics according the feeling parents
timeFrame: At the inclusion
measure: Proportion of maternal migraine
timeFrame: At the inclusion
measure: Proportion of partenal migraine
timeFrame: At the inclusion
measure: Age of begining of colics
timeFrame: At the inclusion
measure: Age of ending of colics
timeFrame: At the inclusion
measure: Proportion of real colics according to Wessel definition in the subgroup of parents who report that their child has colic
timeFrame: at the inclusion
Other outcomes:
Locations:
city: Nancy
country: France
facility: Dr BORSA-DORION Anne
Study officials:
References: