Clinical trial NCT05210920: RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?
Official title: RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Bacterial Infections
Surgical Site Infection
Contaminated Medical or Biological Substances
Lead sponsor: University of North Carolina, Chapel Hill
Sponsor class: OTHER
First posted: 2022-01-27
Enrollment: 53
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: All participants will have all three nail types assessed: regular polish, gel polish and bare nail
Primary purpose: PREVENTION

Brief summary: Purpose: The purpose of this study is to evaluate if type of nail polish (gel polish or regular polish) has an effect on the number of bacterial colonies on finger nails after surgical scrubbing.

Participants: The potential participants are healthcare providers with patient interaction. Exclusion criteria include evidence of active dermatitis or other skin abnormalities, or allergy to chlorhexidine.

Intervention: Participants will have gel nail polish applied to one finger of their dominant hand, and regular polish applied to another finger of their dominant hand. Bacterial swabs will be collected from these two fingers, as well as the from the adjacent finger with no nail polish. Specimen collection will occur both before and after scrubbing with surgical soap. Bacterial counts will be compared between the three groups to determine the association between the presence of nail polish and nail polish type on bacterial counts after surgical scrubbing. Specimen collection will not take place during scrubbing for actual patient care.

Detailed description: Potential participants will be identified by word of mouth, flyers and institutional networking. Once a participant agrees to enroll, they will have each type of nail polish placed on a single finger on their dominant hand (gel on one finger and regular polish on another). A third finger will be left bare to serve as a control. On day 1-3 after nail polish application, the participant will have cotton swab samples taken from underneath their nail and over their nail bed, on each of the two polished nails, as well as the adjacent bare nail. These bacterial samples will be collected both before and after scrubbing (utilizing a nail pick, scrub brush, and chlorhexidine). This process will be repeat on day 5-7 after nail polish application. These samples will then be assessed for bacterial colonies in the Microbiology laboratory. Participant variables will be recorded in RedCap (scrubbing frequency, % of chipping in nails (in quartiles: 0, \< 25%, \< 50%, \<75%, \>75%, Gender, Age, Level of training, Specialty, Type of polish, Dominant hand, Duration since application of polish, Nail length in mm, Race, BMI, Type of bacteria isolated from samples).

Summary of Study Visits:

Day 0 Participants will have polish applied on two fingers on their dominant hand, one with gel polish and one with regular polish.

Day 1-3 The participants will return for their first swabs. Bacterial swabs will be obtained from the nail bed and under the fingernail of 3 fingers: the regular polish nail, the gel polish nail and a bare nail adjacent to the two polished nails, before and after a standard 5-minute scrub with chlorhexidine.

Day 5-7 The participants will return for the same procedure described above. The nail polish can be removed after this intervention. No further follow-up or involvement for participants

Eligibility criteria: Inclusion Criteria:

* Healthcare provider who provides patient care

Exclusion Criteria:

* Active dermatitis or other skin abnormality
* Allergy to chlorhexidine scrub soap

Primary outcomes:
measure: Bacterial Counts Before Scrubbing Day 1-3
timeFrame: 1-3 days after polish application
measure: Bacterial Counts After Scrubbing Day 1-3
timeFrame: 1-3 days after polish application
measure: Bacterial Counts Before Scrubbing Day 5-7
timeFrame: 5-7 days after polish application
measure: Bacterial Counts After Scrubbing Day 5-7
timeFrame: 5-7 days after polish application
Secondary outcomes:
measure: Percent of nail polish flaking (%) Day 1-3
timeFrame: 1-3 days after polish application
measure: Percent of nail polish flaking (%) Day 5-7
timeFrame: 5-7 days after polish application
measure: Nail growth (mm) Day 1-3
timeFrame: 1-3 days after polish application
measure: Nail growth (mm) Day 5-7
timeFrame: 5-7 days after polish application
Other outcomes:
Locations:
city: Chapel Hill
country: United States
facility: UNC Chapel Hill
state: North Carolina
Study officials:
affiliation: University of North Carolina, Chapel Hill
name: Elizabeth Geller, MD
role: PRINCIPAL_INVESTIGATOR
References: