Clinical trial NCT01076114: Comparison of Critical Flicker Fusion Versus Automated Visual Fields in the Detection of Early Glaucoma
Official title: Comparison of Critical Flicker Fusion vs. Automated Visual Fields in the Detection of Early Glaucoma
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Glaucoma
Lead sponsor: Northwell Health
Sponsor class: OTHER
Collaborators: name: Nassau University Medical Center
First posted: 2010-02-25
Enrollment: 58
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Subjects will be selected from routine clinic patients seen at the Eye Center at Nassau University Medical Center, in East Meadow, NY.

Brief summary: The purpose of this study is to evaluate if critical flicker fusion is a more reliable method for detection of early glaucoma compared to automated visual fields in comparison to subjects without evidence of glaucoma or optic nerve disease.

Detailed description: Our hypothesis is that critical flicker fusion (CFF) is a more reliable method for detection of early glaucoma compared to automated visual fields in comparison to subjects without evidence of glaucoma or optic nerve disease. We aim to evaluate the structure of the optic nerve and compare it to results of visual fields and CFF. The CFF will also be correlated with intraocular pressure (IOP) measurements to observe if it may be more closely related than visual fields. This may become an additional tool to detect glaucoma in those with unreliable visual fields or who are unable to perform a visual field from physical or mental limitations.

Eligibility criteria: Inclusion:

* Glaucoma Suspects:
* Abnormal optic disc appearance with increased cup to disc ratio, or
* Increased intraocular pressure \>21 in either eye
* Control Subjects:
* Normal appearing optic discs
* Normal intraocular pressure (\<21)

Exclusion:

* Other ocular pathology
* History of seizures or epilepsy

Primary outcomes:
measure: Difference of mean deviation of glaucoma suspects from controls between critical flicker fusion and automated visual fields.
timeFrame: 1 visit (1 day)
Secondary outcomes:
Other outcomes:
Locations:
city: East Meadow
country: United States
facility: Nassau University Medical Center
state: New York
Study officials:
affiliation: Nassau University Medical Center
name: Colin Scott, MD
role: PRINCIPAL_INVESTIGATOR
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