Clinical trial NCT06680960: Investigation of the Effects of Different Exercise Approaches on Clinical Parameters in Chronic Obstructive Pulmonary Disease Patients
Official title: Investigation of the Effects of Different Exercise Approaches on Exercise Capacity, Muscle Parameters and Quality of Life in Chronic Obstructive Pulmonary Disease Patients
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: COPD (Chronic Obstructive Pulmonary Disease)
Keywords: copd
exercise training
trunk stabilisation
muscle parameters
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2024-11-08
Enrollment: 44
Sex: ALL
Minimum age (years): 40
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The beneficial effects of exercise training in individuals with chronic obstructive pulmonary disease (COPD) are well known. Standard exercise training includes structured aerobic exercise training and resistance exercise training programs applied to upper and lower extremity muscle groups. No study has been found in the literature that includes a trunk stabilization training program that includes muscles that provide whole body stabilization in COPD patients.

Detailed description: The investigators aimed to determine the effects of an aerobic exercise training program, resistance exercise training, and an additional trunk stabilization training program in individuals with COPD.

Individuals diagnosed with COPD between the ages of 40-80 who applied to Ankara Etlik City Hospital Chest Diseases Polyclinic will be included in the study. Data collection tools and exercise training programs will be made by the same researchers. A total of 44 COPD patients, 22 in each group, will be included in the study.

COPD individuals who agree to participate in the study will be randomised electronically using a randomisation program and participants will be divided into two groups.

Group 1: Aerobic exercise training and resistance exercise training and trunk stabilisation strength training Group 2: Aerobic exercise training, resistance exercise training and respiratory exercise training

Eligibility criteria: Inclusion Criteria:

* Having a diagnosis of COPD
* Being between the ages of 40-80
* Being clinically stable (not having had an exacerbation in the last month)
* Being able to cooperate with the tests
* Not participating in any exercise training studies
* Being willing to participate in the study

Exclusion Criteria:

* Having other lung or lung involvement diseases other than COPD
* Having uncontrolled hypertension, arrhythmia and a history of myocardial infarction in the last month, unstable angina, advanced heart failure and other cardiac instability conditions
* Being hemodynamically unstable
* Being on noninvasive mechanical ventilation (NIMV) and long-term oxygen therapy (LTOT)
* Having a history of neuromuscular disease, scoliosis, chest wall surgery
* Being pregnant and having a malignancy
* Having an orthopedic or surgical problem that would prevent participation in tests and exercise training
* Not being willing to participate in the study

Primary outcomes:
measure: Maximal exercise capacity
timeFrame: 8 weeks
Secondary outcomes:
measure: Forced expiratory volume (FEV1)
timeFrame: 8 weeks
measure: Forced Vital Capacity (FVC)
timeFrame: 8 weeks
measure: Respiratory muscle strength
timeFrame: 8 weeks
measure: COPD Assessment Questionnaire
timeFrame: 8 weeks
measure: Muscle activity
timeFrame: 8 weeks
measure: Muscle Thickness
timeFrame: 8 weeks
measure: Timed up and go test
timeFrame: 8 weeks
measure: Functional reach test
timeFrame: 8 weeks
measure: St George Health Questionnaire
timeFrame: 8 weeks
measure: Hospital Anxiety and Depression Scale
timeFrame: 8 weeks
measure: Six Minute Walk Test (6MWT)
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Ankara Etlik City Hospital
Study officials:
References: