Clinical trial NCT07000331: Effectiveness of Exercise and Physical Activity in Individuals.
Official title: Effectiveness of Breathing Exercises and Physical Activity Counseling in Individuals Who Have Had COVID-19.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: COVID-19
Keywords: physical activity
dyspnea
pain
fatigue
anxiety
depression
quality of life
Lead sponsor: Izmir Democracy University
Sponsor class: OTHER
First posted: 2025-06-02
Enrollment: 41
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The effects of breathing exercises and physical activity counseling applied for 4 weeks on the number of daily steps, dyspnea, pain, fatigue, mood and quality of life in individuals who have just had COVID-19 are not yet known. For this reason, it was aimed to investigate in this study.

Detailed description: In the COVID-19 pandemic, which deepened the physical inactivity and sedentary lifestyle, the severity and mortality effect of the virus on humans has decreased today. On the other hand, some symptoms may continue to be seen after recovery in individuals who survived COVID-19. It is known that regular physical activities increase immunity and quality of life, reduce stress, anxiety and depression, and support the musculoskeletal and cardiovascular systems. This study aimed to search effects of breathing exercises and physical activity counseling on the step counts, dyspnea, pain, fatigue, mood and quality of life in individuals with post-COVID-19.

Eligibility criteria: Inclusion Criteria:

* Adult individuals aged 18 and over who volunteered to participate in the research
* Individuals who can understand and answer surveys
* Compatible individuals who can perform exercises and have good cooperation.
* Individuals who were diagnosed with COVID-19 (individuals with a positive Polymerase Chain Reaction (PCR) test result, compatible with COVID-19 infection as a result of lung X-ray or lung tomography despite negative PCR test results) and discharged after recovery/home quarantine completed

Exclusion Criteria:

* Individuals newly diagnosed with COVID-19, therefore in quarantine at home or receiving treatment in hospital
* Individuals with suspected COVID-19
* Pregnant women
* Individuals with serious psychiatric illness and therefore unable to adapt to exercise sessions
* Individuals with severe cognitive impairment
* Individuals with ongoing orthopedic, neurological, cardiovascular disorders and/or problems which are independent of COVID-19

Primary outcomes:
measure: Daily step counts
timeFrame: Baseline, at the end of everyday during 4-week and at 4 weeks after baseline evaluation
Secondary outcomes:
measure: Anxiety score
timeFrame: Baseline and at 4 weeks after baseline evaluation
measure: Depression score
timeFrame: Baseline and at 4 weeks after baseline evaluation
measure: Dyspnea score
timeFrame: Baseline and at 4 weeks after baseline evaluation
measure: Pain score
timeFrame: Baseline and at 4 weeks after baseline evaluation
measure: Fatigue score
timeFrame: Baseline and at 4 weeks after baseline evaluation
measure: Quality of life score
timeFrame: Baseline and at 4 weeks after baseline evaluation
Other outcomes:
Locations:
city: İzmir
country: Turkey
facility: Izmir Democracy University
Study officials:
affiliation: Izmir Democracy University
name: GÜLŞAH BARĞI, Assoc. Dr.
role: STUDY_DIRECTOR
affiliation: Izmir Democracy University
name: SENA UYGUNLAR
role: PRINCIPAL_INVESTIGATOR
affiliation: Izmir Democracy University
name: GÜLCAN POLAT
role: PRINCIPAL_INVESTIGATOR
affiliation: Izmir Democracy University
name: DİLAN SU AKTAŞ
role: PRINCIPAL_INVESTIGATOR
affiliation: Izmir Democracy University
name: UĞUR CANBULAT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Wang TJ, Chau B, Lui M, Lam GT, Lin N, Humbert S. Physical Medicine and Rehabilitation and Pulmonary Rehabilitation for COVID-19. Am J Phys Med Rehabil. 2020 Sep;99(9):769-774. doi: 10.1097/PHM.0000000000001505.
citation: Amini H, Isanejad A, Chamani N, Movahedi-Fard F, Salimi F, Moezi M, Habibi S. Physical activity during COVID-19 pandemic in the Iranian population: A brief report. Heliyon. 2020 Nov;6(11):e05411. doi: 10.1016/j.heliyon.2020.e05411. Epub 2020 Nov 2.