Clinical trial NCT05101395: Prevalence of H. Pylori Gastritis in Sleeve Gastrectomy Specimens
Official title: Prevalence of H. Pylori Gastritis in Sleeve Gastrectomy Specimens: A Cross-Sectional
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Gastritis H Pylori
Gastritis
Obesity Associated Disorder
Keywords: Histopathology
Sleeve gastrectomy
LSG
Gastritis
H. Pylori
Jordan
Middle East
Lead sponsor: University of Jordan
Sponsor class: OTHER
First posted: 2021-11-01
Enrollment: 810
Sex: ALL
Minimum age (years): 12
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Obese patients who undergo sleeve gastrectomy for bariatric reasons

Brief summary: This is a cross-sectional study looking for prevalence of H.Pylori related gastritis among patients underwent sleeve gastrectomy over five year study period. The study also looks for possible association with patients's characteristics. Also, compares its findings with similar regional and international studies.


Eligibility criteria: Inclusion Criteria:

* patients who underwent sleeve gastrectomy
* surgery was performed between January 2015 and October 2019

Exclusion Criteria:

* patients whose resected specimens were not examined histopathologically

Primary outcomes:
measure: Prevalence of gastritis
timeFrame: start to end of the study, 5 years
measure: Prevalence of H.pylori gastritis
timeFrame: start to end of the study, 5 years
Secondary outcomes:
measure: Prevalence of other histopathological findings
timeFrame: start to end of the study, 5 years
measure: likelihood ratio between H.pylori gastritis and advancing age
timeFrame: start to end of the study, 5 years
measure: likelihood ratio between H.pylori gastritis and female gender
timeFrame: start to end of the study, 5 years
measure: likelihood ratio between H.pylori gastritis and BMI
timeFrame: start to end of the study, 5 years
Other outcomes:
Locations:
city: Amman
country: Jordan
facility: Jordan University Hospital
state: Jubaiha
Study officials:
affiliation: Jordan University Hospital
name: Raed Al-Taher, M.D.
role: STUDY_DIRECTOR
affiliation: Jordan University Hospital
name: Mohammad Z Rashdan, M.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: Jordan University Hospital
name: Firas I Obeidat, Prof.
role: STUDY_CHAIR
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