Clinical trial NCT06889220: Investigation of Related Factors in Patients With Non-Specific Neck Pain
Official title: Investigation of Temporomandibular Disorder, Migraine, and Other Related Factors in Patients With Non-Specific Neck Pain
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Neck Pain
Keywords: non-specific neck pain
temporamandibular joint dysfunction
migraine
Health-related quality of life (HRQoL)
Depression
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2025-03-21
Enrollment: 116
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: It is planned that men and women diagnosed with non-specific neck pain between the ages of 18 and 70 will participate in the study.

Brief summary: It has been shown that there is a complex association between neck pain, temporomandibular joint dysfunctions, and migraines, and that these conditions can be influenced by factors such as depression, physical inactivity, and health-related quality of life. Likewise, it is observed that all the factors within this complex structure can actually act as triggers, initiators, or intensifiers of each other.

In recent years, with a more detailed examination of their physiological connections, a reciprocal triangular relationship has been demonstrated between temporomandibular joint (TMJ) dysfunctions, headaches-especially migraines-and neck pain.

A detailed correlation of risk factors affecting neck pain-primarily temporomandibular joint involvement and headaches-in patients with neck pain will help identify underlying secondary effects and facilitate the inclusion of patient-centered, specific exercises in rehabilitation programs for these patients.

Studies in the literature indicate that the relationship between neck pain, temporomandibular joint dysfunctions, and migraines has not been evaluated collectively, and the impact of factors such as depression, physical inactivity, and health-related quality of life on these conditions has not been thoroughly assessed. Therefore, this study aims to comprehensively investigate the effects of temporomandibular joint dysfunctions, migraines, and other associated factors in individuals with non-specific neck pain.


Eligibility criteria: Inclusion Criteria:

* Being between the ages of 18 and 70
* Having non-specific neck pain
* Experiencing migraine-related headaches

Exclusion Criteria:

* Having a diagnosis of cervical trauma, surgery, or disc herniation
* Having a diagnosis of abnormal range of motion in the TMJ or cervical spine, scoliosis, or kyphosis
* Having neurological impairments
* Having systemic diseases
* Having dental or oral pathological lesions, oral infections, facial paralysis, or neuropathic facial pain

Primary outcomes:
measure: Neck Disability Index
timeFrame: Baseline
measure: Migraine Disability Assessment
timeFrame: Baseline
measure: Helkimo Clinical Dysfunction Index
timeFrame: Baseline
Secondary outcomes:
measure: Short Form - 36
timeFrame: Baseline
measure: Beck Depression Inventory
timeFrame: Baseline
measure: International Physical Activity Questionnaire (IPAQ)
timeFrame: Baseline
Other outcomes:
Locations:
city: Yalova
country: Turkey
facility: Yalova university
Study officials:
affiliation: Yalova University
name: Erdi KAYABINAR, PhD
role: PRINCIPAL_INVESTIGATOR
References: