Clinical trial NCT05564455: Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification
Official title: Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power
Lead sponsor: Foundation University Islamabad
Sponsor class: OTHER
First posted: 2022-10-03
Enrollment: 70
Sex: ALL
Minimum age (years): 40
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Prospective, interventional study
Primary purpose: TREATMENT

Brief summary: Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures. We aim to compare the newer generation biometry formula; the Kane formula with the commonly used SRK-T formula for intraocular power calculation in uneventful phacoemulsification surgery to assess the post-operative refractive outcomes at one month post-surgery.

Detailed description: Purpose: To compare post-operative refractive outcome with Sanders Retzlaff Kraff theoretical (SRK T) and Kane formulae for intraocular lens (IOL) power calculation in cataract patients Study Design: Prospective, interventional study Place and Duration of Study: Department of Ophthalmology, Fauji Foundation Hospital, Rawalpindi Material and Methods: A total of a 70 eyes, 35 in each group will be included in our study. The patients will be randomly divided into two groups. In cases of bilateral cataract, one eye will be included in each group for better control. IOL power calculation in Group A will be done with the SRK-T formula and in group 2 with the Kane Formula. Autokeratometry and A-scan ultrasound will be done for biometry. Inclusion criteria will be uncomplicated cataract in both genders. Exclusion criteria will be ocular trauma, uveitis, previous intraocular surgery, or any retinopathy. All patients will undergo phacoemulsification with foldable lens implantation by two experienced surgeons. Post-operative refractive outcome will be evaluated at one month after surgery. The two groups will be compared.

Results: The results will be calculated by SPSS. Conclusion: A conclusion will be drawn on the basis of our results.

Eligibility criteria: Inclusion Criteria:

* Senile cataract (nuclear, cortical, posterior subcapsular, mature, hypermature cataract)
* Absence of other ocular pathology causing diminished visual acuity
* patients above 40 years of age
* Astigmatism \> 2.5 diopters

Exclusion Criteria:

* Retinal diseases
* Maculopathy
* Uveitis
* Complications during phacoemulsification
* Combined procedures
* Previous ocular surgery
* Trauma
* Secondary cataract

Primary outcomes:
measure: Visual acuity (Snellen/logMAR) and refractive error (automated refraction in diopters)
timeFrame: 1 month post-operatively
measure: Spherical equivalent in diopters
timeFrame: 1 hour to 1 year
measure: Post-operative refractive outcome in diopters
timeFrame: 1 hour to 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Rawalpindi
country: Pakistan
facility: Fauji Foundation Hospital
state: Punjab
Study officials:
References: