Clinical trial NCT05529914: Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis
Official title: Effects of Myofascial Release and Neuromuscular Training for Pes Anserine Syndrome Associated With Knee Osteoarthritis: A Randomized Control Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Pes Anserine Bursitis
Lead sponsor: Dow University of Health Sciences
Sponsor class: OTHER
First posted: 2022-09-07
Enrollment: 80
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A randomized control trial will be conducted at the outpatient department of Dow Institute of Physical Medicine and Rehabilitation. A sample size of 80 is calculated using PASS version 11 software. The subjects will be first screened and those who fulfill the inclusion criteria, will be asked to fill the consent form. After selection, the participants will be randomly allocated by the help of computer generated randomization sheet, into two groups i.e. experimental and the control group. The group A will be provided with the myofascial release along with the neuromuscular training whereas the group B will only receive the neuromuscular training. Cold pack will be applied to both the groups. The neuromuscular training consists of warm-up phase, lunges, sideways exercises, wall squats, weight transfer exercises, step up and down and the cool down phase. Total 12 sessions of 35 minutes each will be given to all the participants for about 4 weeks on alternate days. Outcome measures will be analyzed by visual analogue scale (VAS) for pain assessment, goniometry for range of motion and the Knee injury and Osteoarthritis Outcome Score (KOOS) to evaluate the functional assessment of the patients at the baseline and the post intervention.


Eligibility criteria: Inclusion Criteria:

* Male and Females both with the age between 40-60 years.
* Patients with unilateral or bilateral knee osteoarthritis with pes anserine syndrome.
* Patients with knee pain more than 3.4 cm on visual analogue scale as minimum cut of value.
* Kellgren and Lawrence grade II and III on radiological findings.
* Duration of knee osteoarthritis more than 3 months (chronic).

Exclusion Criteria:

* Patients with any neurological disorder.
* Knee deformities such as contractures, genu valgum and genu varum.
* Septic knee arthritis.
* History of ligamentous injury or meniscal tear.
* Cancer or any other malignancy or bone tumor.
* Any history of previous lower limb arthroplasty or other knee surgery.
* Comorbid like diabetes mellitus.
* Inflammatory rheumatic disease (R.A).

Primary outcomes:
measure: Change in pain intensity on visual analogue scale after four weeks
timeFrame: Baseline and 4 weeks
measure: Change in range of motion assessed with universal goniometer after four weeks
timeFrame: Baseline and 4 weeks
Secondary outcomes:
measure: Change in functional disability assessed with Knee injury and osteoarthritis outcome score after four weeks.
timeFrame: Baseline and 4 weeks
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: Dow Institute of Physical Medicine and Rehabilitation
state: Sindh
city: Karachi
country: Pakistan
facility: Sindh Institute of Physical Medicine and Rehabilitation
state: Sindh
Study officials:
affiliation: Dow University of Health Sciences
name: Farhan I Khan, PhD
role: STUDY_DIRECTOR
References: