Clinical trial NCT04014972: Clinical Features, Treatment Mode and Health Outcomes of Chest Pain Patients in China (CHANGE)
Official title: Clinical Features, Treatment Mode and Health Outcomes of Chest Pain Patients in China: China Chest Pain Center Accreditation Programme,CHANGE-chest Pain Research
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Chest Pain Center
STEMI - ST Elevation Myocardial Infarction
Lead sponsor: China Cardiovascular Association
Sponsor class: OTHER
Collaborators: name: Peking University First Hospital
name: Shanghai Zhongshan Hospital
name: Peking University
First posted: 2019-07-10
Enrollment: 50000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The study population was inpatients (18 years and older) admitted to the Chest Pain Central database with symptoms of chest pain.The database registration of this study was conducted in 4129 registered hospitals in 31 provinces in China.All hospitals participating in the Chest Pain Center program are encouraged to manage patients in accordance with local standard practices (as recommended by current Chinese guidelines).

This study will include data on all patients in the chest pain central database.

Brief summary: Chinese Cardiovascular Association is an association dedicated to establishing Chest Pain Centers in hospitals that have basic qualifications and meet pre-designed quality control targets.The vision of Chinese Cardiovascular Association is the cardiovascular health of every Chinese, and the mission is to realize the early arrival of the inflection point of cardiovascular events in China.The institute of China Heart House is responsible for the daily management and implementation of Chinese Cardiovascular Association and the implementation and management of the Chest Pain Center construction project.In order to improve standard treatment and chest pain system management to achieve better outcomes for patients, China Heart House established the chest pain center database.The database includes patients in 4129 registered hospitals in 31 provinces in China who have been admitted with chest pain.The database can reflect the clinical characteristics, treatment and outcome of patients with chest pain in China.

This non-interventional, retrospective study analyzed the chest pain center database to understand the demographics, clinical characteristics, treatment patterns and clinical outcomes of patients with chest pain, and to analyze the effects of different treatment patterns, including chest pain centers and related collaborative treatment networks.The results of the study will assess the gap between the real-world situation and the recommendations of the guidelines and reflect the effect of chest pain centers and related collaborative treatment networks on the treatment process and service quality.The research results can be directly translated into the basis of medical treatment system intervention, and also provide decision-making reference for improving the certification standards and quality control of chest pain centers.


Eligibility criteria: Inclusion Criteria:

* age 18 and above
* patients admitted with chest pain
* diagnosis is made by the treating physician based on local practice and clinical judgment

Exclusion Criteria:

* No

Primary outcomes:
measure: mean and standard deviation of STEMI (ST-segment elevated Myocardial Infarction)patients
timeFrame: baseline
measure: Proportion of STEMI (ST-segment elevated Myocardial Infarction)patients
timeFrame: baseline
measure: emergency information of STEMI patients
timeFrame: baseline
measure: admission status of STEMI patients
timeFrame: baseline
measure: hospitalization evaluation of STEMI patients
timeFrame: baseline
measure: In-hospital mortality of STEMI patients
timeFrame: baseline
measure: Hospitalization days of STEMI patients
timeFrame: baseline
measure: Total cost of STEMI patients
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References: