Clinical trial NCT04235127: The Catalonia Suicide Risk Code Epidemiology Study: an Epidemiological Study of Suicide Attempts in Catalonia, Spain
Official title: The Catalonia Suicide Risk Code Epidemiology Study: a Two-Stage Exposure-Enriched Nested Case-Control Study of Suicide Attempts in Catalonia, Spain
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Suicide, Attempted
Suicide
Suicide and Self-harm
Keywords: nested case-control study
electronic healthcare records
register-based study
incidence
risk factors
risk prediction
machine learning techniques
inverse probability weighting
public health
surveillance
population-attributable risk proportions
Lead sponsor: Hospital del Mar Research Institute (IMIM)
Sponsor class: OTHER
Collaborators: name: Catalan Agency for Health Information, Assessment and Quality
name: National Centre for Suicide Research and Prevention, Norway
name: Harvard Medical School (HMS and HSDM)
First posted: 2020-01-21
Enrollment: 186000
Sex: ALL
Minimum age (years): 10
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: The target population consists of the dynamic cohort of all Catalan residents during the 6-year period 2014-2019.

Brief summary: Suicide attempts (SA) constitute a major public health issue worldwide. Research suggests that 2.7% of adult people ever attempt suicide; among children and adolescents this is estimated to be 6.0%. SA are related to subsequent suicide which represents an annual loss of 34.6 million years of life worldwide. Suicide attempts are also related to persistent physical and mental health issues, psychiatric hospitalizations, impaired academic performance, unemployment, partner abuse victimization and perpetration, having children removed by social services, loneliness, relationship difficulties, impaired social functioning and low life satisfaction. Despite this considerable societal impact, there is a lack of epidemiological research focussing on providing suicide attempt surveillance in the population, to inform public health action aimed at reducing risk for suicide attempts in the population, and to provide data-driven support for suicide risk assessment across healthcare settings. To address this shortcoming, the investigators designed the Catalonia Suicide Risk Code Epidemiology study. Using centralized Electronic Healthcare Record data from the entire public healthcare system of Catalonia, Spain, the CSRC-Epi study aims to estimate reliable suicide incidence rates, identify suicide attempt risk factors, and develop validated suicide attempt risk prediction tools.


Eligibility criteria: Inclusion Criteria:

* Catalan residency during 2014-2019
* age 10 or more at end of observation period

Exclusion Criteria:

* none

Primary outcomes:
measure: Number of catalan residents with suicide attempt (incidence)
timeFrame: 2014-2019
Secondary outcomes:
measure: Number of Catalan residents committing suicide (incidence)
timeFrame: 2014-2019
Other outcomes:
Locations:
Study officials:
References:
citation: Mortier P, Vilagut G, Puertolas Gracia B, De Ines Trujillo A, Alayo Bueno I, Ballester Coma L, Blasco Cubedo MJ, Cardoner N, Colls C, Elices M, Garcia-Altes A, Gene Badia M, Gomez Sanchez J, Martin Sanchez M, Morros R, Prat Pubill B, Qin P, Mehlum L, Kessler RC, Palao D, Perez Sola V, Alonso J; CODIRISC Epidemiology Study Group. Catalonia Suicide Risk Code Epidemiology (CSRC-Epi) study: protocol for a population-representative nested case-control study of suicide attempts in Catalonia, Spain. BMJ Open. 2020 Jul 12;10(7):e037365. doi: 10.1136/bmjopen-2020-037365.