Clinical trial NCT05532592: Investigation on the Hesitancy of COVID-19 Vaccination Among Liver Transplant Recipients in China
Official title: Investigation on the Hesitancy of COVID-19 Vaccination Among Liver Transplant Recipients in China
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Vaccine Hesitancy
Keywords: COVID-19
vaccine
vaccine hesitancy
liver transplant recipients
China
Lead sponsor: RenJi Hospital
Sponsor class: OTHER
First posted: 2022-09-08
Enrollment: 449
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The subjects of this study were adult recipients who were followed up after liver transplantation in the department of Liver Surgery, Renji Hospital Shanghai Jiao Tong University.

Brief summary: On WeChat platform, through a point-to-point connection, and carry on the questionnaire survey to collect information of liver transplant recipients followed-up by the department of Liver Surgery, Renji Hospital Shanghai Jiao Tong University. Patients meeting inclusion and exclusion criteria will be selected. Conduct statistical analysis to describe the incidence of adverse reactions related to COVID-19 vaccine after liver transplantation, and to compare and evaluate the factors leading to COVID-19 vaccine hesitancy.

Detailed description: On WeChat platform, through a point-to-point connection, and carry on the questionnaire survey to collect information of liver transplant recipients followed-up by the department of Liver Surgery, Renji Hospital Shanghai Jiao Tong University. Questionnaire items including demographic characteristics, understanding of COVID-19, attitude toward COVID-19 vaccine. Patients meeting inclusion and exclusion criteria will be selected. Conduct statistical analysis to describe the incidence of adverse reactions related to COVID-19 vaccine after liver transplantation, and to compare and evaluate the factors leading to COVID-19 vaccine hesitancy.

Eligibility criteria: Inclusion Criteria:

1. age ≥ 18
2. recipients after liver transplantation surgery

Exclusion Criteria:

1. Incomplete data (missing questionnaire information), such as lack of age, gender, indication for transplantation, time after transplantation and other indicators
2. loss to follow-up
3. COVID-19 vaccination before liver transplantation

Primary outcomes:
measure: Number of Participants with COVID-19 Vaccine Hesitancy
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Shanghai
country: China
facility: The department of Liver Surgery, Renji Hospital Shanghai Jiao Tong University.
state: Shanghai
Study officials:
affiliation: The department of Liver Surgery, Renji Hospital Shanghai Jiao Tong University.
name: Yongbing Qian, Prof
role: STUDY_DIRECTOR
References:
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