Clinical trial NCT04264312: Baseline Investigation of Chronic Hepatitis B Viruses Infections: Who is Eligible for Treated Criteria
Official title: Beijing Center for Disease Prevention and Control
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hepatitis B
Keywords: HBV
Antiviral Treatment Rate
China
Baseline Investigation
Lead sponsor: Centers for Disease Control and Prevention, China
Sponsor class: OTHER_GOV
First posted: 2020-02-11
Enrollment: 76220
Sex: ALL
Minimum age (years): 25
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: The study population are Residents with medical insurance who were older than 25 years and lived in Beijing more than 6 months. The population who are with pacemakers and ascites, pregnant, and whose wound was not cured at right upper abdomen were excluded.

Brief summary: Through two-stage stratified cluster sampling, investigators studied the antiviral treatment rate and the main factors affecting the antiviral treatment in community chronic HBV infection-related liver disease population.

Detailed description: Hepatitis B virus (HBV) infection is a major public health problem worldwide. China has the world's largest burden of HBV infection and will be a major contributor towards the global elimination of hepatitis B disease by 2030. While, the antiviral treatment rate and the main factors affecting the antiviral treatment in community chronic HBV infections is still unknown. In response to the above situation, Sampling applied a two-stage stratified cluster sampling design in 16 Districts and 331 Townships. Investigators wanted to know the one who is eligible for treated criteria based on community in 25 and over years old in Beijing.

Eligibility criteria: Inclusion Criteria:

* older than 25 years old;
* Residents with medical insurance coverage lived in Beijing more than 6 months .

Exclusion Criteria:

* Persons with pacemakers;
* Pregnant women;
* Persons with ascites;
* The one whose wound was not cured at the right upper abdomen

Primary outcomes:
measure: HBsAg positive rate
timeFrame: Baseline
measure: Average rate of chronic hepatitis B accepting antiviral treatment
timeFrame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: Xicheng District Center for Disease Prevention and Control
state: Beijing
city: Beijing
country: China
facility: Huairou District Center for Disease Prevention and Control
state: Beijing
city: Beijing
country: China
facility: Daxing District Center for Disease Prevention and Control
state: Beijing
city: Beijing
country: China
facility: Chaoyang District Center for Disease Control and Prevention
state: Beijing
city: Beijing
country: China
facility: Dongcheng District Center for Disease Control and Prevention
state: Beijing
city: Beijing
country: China
facility: Fengtai District Center for Disease Control and Prevention
state: Beijing
city: Beijing
country: China
facility: Changping District Center for Disease Prevention and Control
city: Beijing
country: China
facility: FangShan District Center for Disease Prevention and Control
city: Beijing
country: China
facility: Haidian District Center for Disease Prevention and Control
city: Beijing
country: China
facility: Miyun District Center for Disease Prevention and Control
city: Beijing
country: China
facility: Tongzhou District Center for Disease Prevention and Control
Study officials:
affiliation: Beijing Center for Disease Prevention and Control
name: Jiang Wu
role: STUDY_DIRECTOR
References: