Clinical trial NCT03619720: Emotional Perception and Production in Facial Palsy: Respiratory, Vocal and Facial Markers.
Official title: Production et Perception émotionnelle Chez Les Patients paralysés Faciaux: Marqueurs Respiratoires, Phonatoires et expressivité Faciale.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Facial Palsy
Keywords: Emotions, Respiratory Rate, Phonation
Lead sponsor: Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Sponsor class: OTHER
First posted: 2018-08-08
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SCREENING

Brief summary: Respiratory function, phonation and facial expressivity are related to emotional reaction through neurophysiological process. Specific emotional respiratory, vocal and facial patterns had been described in literature. Respiratory cycles variation is modulated by stimulus arousal. Furthermore, inspiratory-to-expiratory time ratio in abdominal area is modulated by emotional valence. Inextricably linked to respiration, vocal production depends on emotional arousal and valence too.

According to embodied cognition, the effector pattern of an emotion initiates the corresponding subjective activation. Facial recognition is influenced by automatic mimicry and facial feedback. Most facial feedback studies included patients with diplegia but few studies dealt with emotional perception in Bell's palsy.

The aim of the present study is to understand production and perception of emotion in Bell's palsy with respiratory, vocal and facial markers. What impact lack of mimicry have on physiological emotional reaction in Bell's palsy? To this end, prospective monocentric study will be conducted with 60 patients with Bell's Palsy from grade II to grade VI of House \& Brackmann's scale. During production and perception of vocal and facial expression, respiratory rate and thoraco-abdominal movements will be analyzed. The investigators hypothesize that severity of facial deficit is negatively correlated with variation of respiratory cycles, lower segmental and suprasegmental changes during vocal expression, and lower facial perception (congruency and arousal).


Eligibility criteria: Inclusion Criteria:

* Patients affiliated to the health care system
* Patients must have been diagnosed with unilateral peripheral facial palsy stage III to VI, according to House and Brackmann international classification.
* To be able to read, understand and sign a consent
* To be able to understand French spoken and written

Exclusion Criteria:

* Diplegia or facial graft
* Visual disorders, non corrected
* Respiratory or vocal disorders
* Psychiatric history
* Facial surgery

Primary outcomes:
measure: Effects of facial impairment on the respiratory rate
timeFrame: 1hour
Secondary outcomes:
measure: Effects of facial impairment on pitch variation (Hz) during emotional vocal production.
timeFrame: 1hour
measure: Effects of facial impairment on perception of emotional facial displays.
timeFrame: 1hour
Other outcomes:
Locations:
city: Paris
country: France
facility: Laboratoire de Physiopathologie Respiratoire du Service de Pneumologie et de Réanimation
Study officials:
affiliation: Laboratoire de physiopathologie respiratoire, UMR_S 1158 INSERM/UPMC " Neurophysiologie Respiratoire Expérimentale et Clinique "
name: Peggy Gatignol
role: PRINCIPAL_INVESTIGATOR
References: