Clinical trial NCT05365295: Study of ADHD Children's Sensitivity to Memory Error Production
Official title: Sensitivity of Children With Attention Deficit/Hyperactivity Disorder to Memory Error Production
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: ADHD
Lead sponsor: University Hospital, Angers
Sponsor class: OTHER_GOV
First posted: 2022-05-09
Enrollment: 28
Sex: ALL
Minimum age (years): 96
Maximum age (years): 131
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SCREENING

Brief summary: The purpose of the study is to test whether children with Attention Deficit/Hyperactivity Disorder (ADHD) are more susceptible to false memory production using a DRM paradigm. The number of "critical decoy production" errors will be analyzed and compared to the calibration of the test.

Detailed description: During a neuropsychological assessment, as part of the clinical routine, children with a diagnosis of ADHD, without neurological etiology, aged 8 to 10 years will be offered an additional task. This task, a DRM adapted to the child, consists of learning several lists of words. Each list exposes words belonging to the same lexical field, to a concept not explicitly mentioned in the list, called critical lure. Immediately after the presentation of a list, the child is asked to recall as many words as possible. Recall of the critical lure gives an indication of the production of false memories. The number of critical lures produced by these children will be compared to the calibration of the test, currently being published. The investigator will also verify if the production of critical lures can be correlated with other variables such as performance on intellectual, executive and attentional tasks, proposed during the clinical routine assessment.

The investigator hypothesize that ADHD children will recall more critical lures than the norm, and fewer correct responses than the norm.

The data collected is taken from the child's psychological file. The only personal information used, beyond test performance, is the child's gender and age. The procedure is anonymous.

Eligibility criteria: Inclusion Criteria:

* Age between 96 and 131 months
* Child referred by a doctor for a neuropsychological assessment
* Child with ADHD diagnosis
* Sufficient command of the French language
* Non-opposition of the child and his/her parents

Exclusion Criteria:

* Severe psychiatric comorbidity: major depressive episode, bipolar disorder, generalized anxiety disorder, autism spectrum disorder
* Major neurological history: severe head trauma, stroke, severe epilepsy, brain tumor
* Repeating a class during school
* Presence of an intellectual disability
* Use of methylphenidate treatment less than 48 hours before the experiment
* Completion of an intellectual assessment using the Wechsler Intelligence Scale for Children (WISC-V) dated less than one year before the meeting

Primary outcomes:
measure: DRM (Deese-Roediger-McDermott task) Performance 1
timeFrame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
measure: DRM (Deese-Roediger-McDermott task) Performance 2
timeFrame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
measure: DRM (Deese-Roediger-McDermott task) Performance 3
timeFrame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
measure: DRM (Deese-Roediger-McDermott task) Performance 4
timeFrame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
measure: DRM (Deese-Roediger-McDermott task) Performance 5
timeFrame: 20 minutes during DRM DRM (Deese-Roediger-McDermott) task
Secondary outcomes:
Other outcomes:
Locations:
city: Angers
country: France
facility: neuropediatrics department - university hospital center of Angers
city: Rezé
country: France
facility: Multidisciplinary liberal practice - Acropole Santé
Study officials:
affiliation: UH Angers
name: Pierre Martin
role: PRINCIPAL_INVESTIGATOR
References: