Clinical trial NCT04779476: Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial
Official title: Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Facial Pain
Pain, Postoperative
Pain, Orofacial
Keywords: Alveogyl
Eugenol
Dental extraction
Post extraction pain
Lead sponsor: Riyadh Elm University
Sponsor class: OTHER
First posted: 2021-03-03
Enrollment: 50
Sex: ALL
Minimum age (years): 13
Maximum age (years): 22
Standard ages: CHILD
ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients referred from the orthodontic department for extraction of p

Brief summary: This study aims to assess the post-dental extraction pain following the application of two different dressing materials.

Alvogyl® and Absorbable gelatin sponges

Detailed description: Effective postoperative pain relief improves the quality of recovery and the resumption of normal activities. Many options are available for postoperative pain relief following tooth extraction including systemic analgesic, intra-alveolar socket dressing medicaments, and follow the postoperative instructions; the choice of the medication determined by drug availability, chance of side effect of some drugs and financial considerations. The use of intra-alveolar dressing materials is widely suggested in the literature such as Alvogyl® that used as palliative treatment which includes eugenol (analgesic, anti-inflammatory), iodoform (antimicrobial), and butamen (anesthetic). Absorbable gelatin sponges contain haemostatic material and may be used for local application in surgical procedures where traditional haemostasis is difficult. In addition to its haemostatic effect, an absorbable gelatin sponge can be used as a drug reservoir to provide sustained release of drugs

The aim of this study is to measure the pain intensity after using socket dressing materials following tooth extraction.

Eligibility criteria: Inclusion Criteria:

* Single tooth extraction
* Upper and lower teeth

Exclusion Criteria:

* Surgical extraction
* Medically compromised patients
* Presence of active infection
* Presence of pathology

Primary outcomes:
measure: 3 hrs post extraction pain
timeFrame: three hours after the extraction
measure: 6 hrs post extraction pain
timeFrame: six hours after the extraction
measure: 12 hrs post extraction pain
timeFrame: twelve hours after the extraction
measure: 24 hrs post extraction pain
timeFrame: twenty-four hours after the extraction
Secondary outcomes:
Other outcomes:
Locations:
city: Riyadh
country: Saudi Arabia
facility: Ahmad Assari
Study officials:
References:
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citation: Summers L, Matz LR. Extraction wound sockets. Histological changes and paste packs--a trial. Br Dent J. 1976 Dec 21;141(12):377-9. doi: 10.1038/sj.bdj.4803851. No abstract available.
citation: Kaur G, Athar M, Alam MS. Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis. Mol Carcinog. 2010 Mar;49(3):290-301. doi: 10.1002/mc.20601.
citation: Kafali H, Iltemur Duvan C, Gozdemir E, Simavli S, Ozturk Turhan N. Placement of bupivacaine-soaked Spongostan in episiotomy bed is effective treatment modality for episiotomy-associated pain. J Minim Invasive Gynecol. 2008 Nov-Dec;15(6):719-22. doi: 10.1016/j.jmig.2008.08.006.