Clinical trial NCT02319473: Jakarta Acute Coronary Syndrome Registry
Official title: Jakarta Acute Coronary Syndrome Registry
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Acute Coronary Syndrome
Keywords: system of care
acute myocardial infarction
registry
Primary PCI
Fibrinolytic therapy
Lead sponsor: National Cardiovascular Center Harapan Kita Hospital Indonesia
Sponsor class: OTHER
First posted: 2014-12-18
Enrollment: 28812
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All acute coronary syndrome patients admitted to the emergency department.

Brief summary: Jakarta acute coronary syndrome enrolled patients with acute coronary syndrome admitted to the emergency department of all health centers in Jakarta and the surrounding area.

Detailed description: The JAC registry is an ongoing prospective, multi center, observational study that aims to enroll ACS patients who admitted to the emergency department (ED) of all health centers in Jakarta and the surrounding area. The registry has been collecting data since 2007, and used extensively since 2014.

Currently, the JAC registry is the main source of data for measuring the performance of the STEMI network in the region, namely Jakarta Cardiovascular Care Unit Network System. The STEMI network in Jakarta has been introduced as an integral part of the government project since 2010/2011.

STEMI was diagnosed based on the typical chest pain and ST segment elevation on two or more contiguos leads. The number of primary PCI, fibrinolytic therapy and non-reperfused patients were recorded.

Eligibility criteria: Inclusion Criteria:

* STEMI patients that was diagnosed based on the presence of typical chest pain and ST-segment elevation in two or more contigious leads on the initial ECG

Exclusion Criteria:

* STEMI patients that was under 18 years

Primary outcomes:
measure: The number of primary PCI
timeFrame: 15 years
measure: In-hospital mortality
timeFrame: 15 years
Secondary outcomes:
measure: The number of fibrinolytic therapy
timeFrame: 15 years
measure: The number of non-reperfused patients
timeFrame: 15 years
Other outcomes:
Locations:
city: Jakarta
country: Indonesia
facility: National Cardiovascular Center Harapan Kita
Study officials:
affiliation: National Cardiovascular Center Harapan Kita
name: Surya Dharma, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Dharma S, Andriantoro H, Purnawan I, Dakota I, Basalamah F, Hartono B, Rasmin R, Isnanijah H, Yamin M, Wijaya IP, Pratama V, Gunarto TB, Juwana YB, Suling FR, Witjaksono AM, Lasanudin HF, Iskandarsyah K, Priatna H, Tedjasukmana P, Wahyumandradi U, Kosasih A, Budhiarti IA, Pribadi W, Wirianta J, Lubiantoro U, Pramesti R, Widowati DR, Aminda SK, Basalamah MA, Rao SV. Characteristics, treatment and in-hospital outcomes of patients with STEMI in a metropolitan area of a developing country: an initial report of the extended Jakarta Acute Coronary Syndrome registry. BMJ Open. 2016 Aug 31;6(8):e012193. doi: 10.1136/bmjopen-2016-012193.
citation: Dharma S, Andriantoro H, Dakota I, Purnawan I, Pratama V, Isnanijah H, Yamin M, Bagus T, Hartono B, Ratnaningsih E, Suling F, Basalamah MA. Organisation of reperfusion therapy for STEMI in a developing country. Open Heart. 2015 May 21;2(1):e000240. doi: 10.1136/openhrt-2015-000240. eCollection 2015.
citation: Dharma S, Siswanto BB, Firdaus I, Dakota I, Andriantoro H, Wardeh AJ, van der Laarse A, Jukema JW. Temporal trends of system of care for STEMI: insights from the Jakarta Cardiovascular Care Unit Network System. PLoS One. 2014 Feb 10;9(2):e86665. doi: 10.1371/journal.pone.0086665. eCollection 2014.
citation: Dharma S, Juzar DA, Firdaus I, Soerianata S, Wardeh AJ, Jukema JW. Acute myocardial infarction system of care in the third world. Neth Heart J. 2012 Jun;20(6):254-9. doi: 10.1007/s12471-012-0259-9.
citation: Dharma S, Mahavira A, Haryono N, Sukmawan R, Dakota I, Siswanto BB, Rao SV. Association of Hyperglycemia and Final TIMI Flow with One-Year Mortality of Patients with Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary PCI. Int J Angiol. 2019 Sep;28(3):182-187. doi: 10.1055/s-0039-1691811. Epub 2019 Jun 17.