Clinical trial NCT06525012: Observational Study on Mortality and Outcome of Patients Hospitalized for Subarachnoid Hemorrhage of Aneurysmal Origin in Martinique Between 2013 and 2021
Official title: Observational Study on Mortality and Outcome of Patients Hospitalized for Subarachnoid Hemorrhage of Aneurysmal Origin in Martinique Between 2013 and 2021
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Subarachnoid Hemorrhage of Aneurysmal Cause
Keywords: SAH (Subarachnoid Hemorrhage)
Ruptured intracranial aneurysm
Modified Rankin score
Mortality
Patient autonomy
Patient dependence
Lead sponsor: University Hospital Center of Martinique
Sponsor class: OTHER
First posted: 2024-07-29
Enrollment: 122
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients hospitalized in Martinique for subarachnoid hemorrhage of aneurysmal origin

Brief summary: The aim of our study is to analyze mortality and sequelae of subarachnoid hemorrhage of aneurysmal origin in hospitalized patients in Martinique. Predictive factors of poor prognosis will also be analyzed.

Detailed description: Subarachnoid hemorrhage is an uncommon pathology in the general population, with a worldwide incidence of 9 per 100,000 people/year, but with a non-negligible risk of sequelae in terms of impairments, activity limitations and participation restrictions of around 30%. Mortality remains high at 40%, despite increasingly specialized care.

In addition, there are a number of objective, rapid assessment scores for autonomy and impairments, notably the modified Rankin score, which is not specific to subarachnoid hemorrhage, but which enables the study of patients' perceived quality of life. Certain factors predictive of bad patient outcome are known in the literature, but have been little studied in the population of Martinique.

Eligibility criteria: Inclusion Criteria:

* Adult (≥18 years) patients,
* Admitted to University Hospital of Martinique with subarachnoid hemorrhage of aneurysmal origin between 01/01/2013 and 31/12/2021,
* Informed patient/next-of-kin/treating physician consent for research participation.

Exclusion Criteria:

* Other causes of subarachnoid hemorrhage of non-aneurysmal origin (traumatic, arteriovenous malformation, cerebral tumor, cerebral thrombophlebitis).

Primary outcomes:
measure: Evaluate mortality in patients hospitalized for subarachnoid hemorrhage of aneurysmal origin over a 9-year period (2013-2021) in Martinique.
timeFrame: 6 months
Secondary outcomes:
measure: Evaluate the clinical outcome of these patients.
timeFrame: 6 months
measure: Analyze the factors associated with a significant impairment of autonomy and/or dependence.
timeFrame: 6 months
measure: Analyze the factors associated with death.
timeFrame: 6 months
measure: Analyze the factors associated with a poor prognosis (death AND/OR significant impairment of autonomy/dependence).
timeFrame: 6 months
Other outcomes:
Locations:
city: Fort-de-France
country: Martinique
facility: University Hospital Center of Martinique
Study officials:
References: