Clinical trial NCT06828523: Assessing Perceptual Effects of Interactive Tasks
Official title: Assessing Perceptual Effects of Interactive Tasks
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Amyotrophic Lateral Sclerosis
Lead sponsor: Penn State University
Sponsor class: OTHER
Collaborators: name: National Institute on Deafness and Other Communication Disorders (NIDCD)
First posted: 2025-02-14
Enrollment: 1300
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Listeners will hear recorded speech of PALS and age-matched speakers and indicate what they heard. Recorded speech consists of vowels and consonants produced in non-interactive and interactive tasks. The perceptual judgements will be compared to see whether interactive contexts have similar perceptual effects across the two groups.

Plans for Assignment - This is a single group study in which all participants will engage in the same tasks.
Primary purpose: BASIC_SCIENCE

Brief summary: In this study, we will evaluate how solo, naive listeners perceive the speech of people with amyotrophic lateral sclerosis (ALS) and age-matched speakers produced across interactive and non-interactive contexts with an unfamiliar, naive interlocutor.

Detailed description: Listeners will hear recorded speech of PALS and age-matched speakers and indicate what they heard. Recorded speech consists of vowels and consonants produced in non-interactive and interactive tasks. The perceptual judgements will be compared to see whether interactive contexts have similar perceptual effects across the two groups.

Plans for Assignment - This is a single group study in which all participants will engage in the same tasks.

Delivery of Intervention: Solo listeners will participate in this study in a remote, asynchronous format. They will be recruited using the online participant recruitment platform Prolific © and will use their own laptop/computer and headphones.

Adequacy of Sample size: We will use n = 1300 listeners to achieve 80% power at alpha of .05 to detect between group differences with the assumption of medium effect sizes (Cohen's f = 0.3).

Adequacy of Analyses: The proposed statistical analyses (Generalized mixed effects regressions) are standard and will be used to analyze the effect of the intervention on the outcome measures described below.

Eligibility criteria: Inclusion Criteria:

* passing the remote hearing screening
* having no known speech, language or neurological disorders per self-report
* being a native monolingual speaker of American English
* having no experience communicating with people with dysarthria
* being between the ages of 18 and 65.

Exclusion Criteria:

* None - if volunteer meets the inclusion criteria, then they will be enrolled

Primary outcomes:
measure: Intelligibility of recorded speech
timeFrame: one 20 minute session
Secondary outcomes:
Other outcomes:
Locations:
city: University Park
country: United States
facility: Speech Core, Pennsylvania State University
state: Pennsylvania
Study officials:
affiliation: The Pennsylvania State University
name: Jimin Lee, Ph.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: The Pennsylvania State University
name: Navin Viswanathan, Ph.D.
role: PRINCIPAL_INVESTIGATOR
affiliation: The Pennsylvania State University
name: Anne Olmstead, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Olmstead, A. J., Viswanathan, N., Cowan, T., & Yang, K. (2021). Phonetic adaptation in interlocutors with mismatched language backgrounds: A case for a phonetic synergy account. Journal of Phonetics, 87, 101054. . : . .
citation: Olmstead AJ, Lee J, Viswanathan N. The Role of the Speaker, the Listener, and Their Joint Contributions During Communicative Interactions: A Tripartite View of Intelligibility in Individuals With Dysarthria. J Speech Lang Hear Res. 2020 Apr 27;63(4):1106-1114. doi: 10.1044/2020_JSLHR-19-00233. Epub 2020 Apr 17.