Clinical trial NCT04734795: The Prevalence of Dysfunctional Breathing in Children and Adolescents With Asthma
Official title: The Prevalence of Dysfunctional Breathing in Children and Adolescents With Asthma
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Dysfunctional Breathing
Asthma in Children
Asthma
Keywords: Dysfunctional breathing
Asthma in children
Asthma in adolescents
Lead sponsor: Kolding Sygehus
Sponsor class: OTHER
Collaborators: name: Odense Patient Data Explorative Network
First posted: 2021-02-02
Enrollment: 363
Sex: ALL
Minimum age (years): 10
Maximum age (years): 17
Standard ages: CHILD
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Children and adolecents with asthma in a hospital outpatient clinic

Brief summary: The purpose of the study is to investigate the prevalence of dysfunctional breathing in children and adolescents with asthma in a hospital outpatient clinic.

Participants are invited to take the Nijmegen Questionnaire and the Asthma Control Questionnaire. The prevalence of dysfunctional breathing defined as NQ score \>= 23 is calculated, and demographics are compared between children with and without dysfunctional breathing.

Detailed description: The purpose of the study is to investigate the prevalence of dysfunctional breathing in children and adolecents with asthma in a hospital outpatient clinic.

Participants are invited to take the Nijmegen Questionnaire and the Asthma Control Questionnaire, during appointments at the outpatient clinic. For this study purpose, each participant only takes the questionnairres once.

Patient data regarding age, sex, asthma medication, lung function, allergic sensitization, method of asthma diagnose, Height, weight and Body mass index is registered from the electronical patient journal.

The prevalence of dysfunctional breathing in the cohort is calculated as the fraction of children with a NQ score \>= 23.

The group of children and adolescents with dysfunctional breathing is characterized and compared to the group without dysfunctional breathing, regarding the descriptives mentioned above.

Eligibility criteria: Inclusion Criteria:

* Asthma diagnosed by lung function tests and/or typical symptoms.
* Treatment with inhaled corticosteroids in minimum 3 months.

Exclusion Criteria:

• Other significant cardiopulmonary or muscoluskeletal conditions.

Primary outcomes:
measure: Prevalence of children with dysfunctional breathing defined as Nijmegen Questionnaire ( NQ) Score >= 23
timeFrame: 1 year
Secondary outcomes:
measure: Mask score
timeFrame: 1 year
measure: Asthma Control Questionnaire ( ACQ5)
timeFrame: 1 year
measure: Age
timeFrame: 1 year
measure: Sex
timeFrame: 1 year
measure: Standardised body mass index (BMI_SDS)
timeFrame: 1 year
measure: The reported use of rescue Beta2 agonist in puffs per week
timeFrame: 1 year
measure: Forced expiratory volume inthe first second in percent of expected Value. ( FEV1%)
timeFrame: 1 year
measure: Method of asthma diagnose
timeFrame: 1 year
Other outcomes:
Locations:
city: Kolding
country: Denmark
facility: Kolding Sygehus
Study officials:
affiliation: Kolding Sygehus
name: Signe Vahlkvist
role: PRINCIPAL_INVESTIGATOR
References: