Clinical trial NCT05374382: A Prehab Strengthening Program Prior to ACL Surgery on Lower Limb Structure and Function
Official title: The Effects of a Lower Limb Strengthening Training Program During Prehabilitation Prior to ACL Surgery on Lower Limb Structure and Function : a Randomized Clinical Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: ACL Injury
Keywords: rehabilitation
strengthening
physiotherapy
atrophy
Lead sponsor: Université de Nantes
Sponsor class: OTHER
First posted: 2022-05-16
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Atrophy and weakness are ubiquitous after a ACL rupture and associated with a worsened long-term recovery of individual capacities, despite surgery and rehabilitation. Preoperative rehabilitation (prehab) is believed to prepare patients for surgery and post-operative rehabilitation. However, prehab programs are highly variable, and do not always aim to develop/maintain neuromuscular parameters.

The purpose of this study is to assess the effects of a lower limb strengthening training program during prehab prior to ACL Surgery on lower limb structure and function.

Detailed description: Recruited participants will be randomly allocated to one of the three groups of participants constituted in this study.

The two first groups will receive prehabilitation prior to ACL reconstruction (differing in program type). All participants will receive standardized post-surgery rehabilitation (based on international recommandations).

Eligibility criteria: Inclusion Criteria:

* age : 18 to 55
* first episode of ACL injury
* having a planed ACL reconstruction
* volunteer to participate

Exclusion Criteria:

* age : \<18 or \>55
* previous episode of ACL injury/reconstruction
* no ACL reconstruction

Primary outcomes:
measure: Changes in muscle strength of the knee muscles
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
measure: Change in muscle volume of the knee muscles
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
measure: Change in the stiffness of knee muscles
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
measure: Change in lower limb function
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
measure: Change in patient's opinion about the knee and associated problems
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
measure: Change in patient's opinion to return to sport
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
Secondary outcomes:
measure: Health consumption
timeFrame: week 0 (baseline); week 9 (post-intervention, short term) ; 6 months after the surgery (post-intervention, mid-term) and 12 months after the surgery (post-intervention, long-term)
Other outcomes:
Locations:
city: Nantes
country: France
facility: Université de Nantes - MIP UR 4334 (Motricity, Movement, Interactions)
Study officials:
affiliation: Université de Nantes
name: Guillaume Le Sant, PhD, PT
role: PRINCIPAL_INVESTIGATOR
References: