Clinical trial NCT03658512: Tübinger Diabetes Mellitus Database (TUEDID)
Official title: Tübinger Diabetes Mellitus Database (TUEDID)
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Diabetes Mellitus
Lead sponsor: University Hospital Tuebingen
Sponsor class: OTHER
First posted: 2018-09-05
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: People with or without diabetes who are treated at the University Hospital Tübingen

Brief summary: Diabetes mellitus is a widespread disease with increasing prevalence worldwide. Patients with diabetes can develop multiple late complications such as neuropathy, retinopathy, nephropathy and cardiovascular comorbidities. So far, there are no reliable predictive tools or markers to estimate if, when and to what extent a patient with diabetes develops late complications. For the patients quality of life and for health economic reasons an improved risk assessment would be desirable. The prospective TUEDID study will characterize diabetic patients to look out for parameters the predict progression of diabetes and its complications.


Eligibility criteria: Inclusion Criteria:

* \>18 years

Exclusion Criteria:

* no written informed consent

Primary outcomes:
measure: Glycemic control (blood glucose)
timeFrame: At enrolment
measure: Glycemic control (HbA1C)
timeFrame: At enrolment
Secondary outcomes:
Other outcomes:
measure: Liver function
timeFrame: At enrolment
measure: Renal function
timeFrame: At enrolment
measure: Glomerular filtration rate (GFR)
timeFrame: At enrolment
measure: Lipid status
timeFrame: At enrolment
measure: Inflammation
timeFrame: At enrolment
measure: Insulinemia
timeFrame: At enrolment
measure: Hormones
timeFrame: At enrolment
measure: Hormones
timeFrame: At enrolment
measure: Hormones
timeFrame: At enrolment
measure: Urine parameters
timeFrame: At enrolment
measure: Urine parameters
timeFrame: At enrolment
measure: Urine parameters
timeFrame: At enrolment
measure: Pancreas
timeFrame: At enrolment
measure: Coagulation
timeFrame: At enrolment
measure: Angiological examination
timeFrame: At enrolment
measure: Measurement of height and weight
timeFrame: At enrolment
measure: Measurement of waist and hip circumference
timeFrame: At enrolment
measure: Blood pressure
timeFrame: At enrolment
measure: Heart rate
timeFrame: At enrolment
measure: Measurement of advanced glycation endproducts
timeFrame: At enrolment
measure: Body composition
timeFrame: At enrolment
measure: Pulmonary function (optional)
timeFrame: At enrolment
measure: Retinal examination
timeFrame: At enrolment
measure: Anamnestic and Lifestyle questionnaire
timeFrame: At enrolment
measure: cognitive testing
timeFrame: At enrolment
measure: Stool examination (single stool sample)
timeFrame: At enrolment
measure: Macronutrient absorption (optional)
timeFrame: At enrolment
measure: Nasal and skin swab
timeFrame: At enrolment
Locations:
city: Tuebingen
country: Germany
facility: University of Tuebingen, Internal medicine IV
Study officials:
References: