Clinical trial NCT06891014: Effects of Regular Exercise on Sensory-motor Functions and Fall Risk in the Elderly
Official title: Effects of Regular Exercise on Sensory-motor Functions and Fall Risk in the Elderly
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Fall Risk
Exercise
Functional Outcomes
Aging
Lead sponsor: Cyprus International University
Sponsor class: OTHER
First posted: 2025-03-24
Enrollment: 92
Sex: FEMALE
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Cross-Sectional Case Control
Primary purpose: TREATMENT

Brief summary: Falls in elderly population are an important public health problem. The aim of this study is to examine the vibration, proprioception, muscle strength, static balance, reaction time and postural stability parameters of female individuals aged 65 and over who exercise regularly by comparing them with sedentary female individuals in the same age group and to determine the effect rates of these parameters on fall risk. A total of 92 individuals will evaluate in the study, including 46 participants who perform regular exercise and 46 participants with a sedentary lifestyle. Participants who performs regular exercise will determine among individuals who going to participate in a combined exercise program under the control of a physiotherapist, 2-3 days a week for 8 weeks. The socio-demographic characteristics, health conditions and exercise habits of the participants will be recorded. For evaluating the physical activity levels of the participants, the International Physical Activity Questionnaire-short form (IPAQ-SF); for vibration sense evaluation, 128-Hz frequency tuning fork; for the evaluation of proprioception sense, angle repetition test; for the isometric muscle strength assessment, digital hand dynamometer; for static balance evaluation, standing stork balance test; for reaction time evaluation, MoART measuring device; for postural stability evaluation, PROKIN-PK200W\* (Tecnobody, Italy) device and for fall risk assessment, Morse fall scale and MAHC-10 fall questionnaire will be used.


Eligibility criteria: Inclusion Criteria:

* Sedentary individuals with an International Physical Activity Questionnaire (IPAQ) score of \<600 (for control group)
* Individuals who will be participated in an eight-week regular exercise program (for the exercise group)
* Those who scored 24 or higher on the standardized Mini-Mental State Examination, individuals without communication problems, and those who were not bedridden or wheelchair-bound.

Exclusion Criteria:

* Individuals who had received any diagnosis/treatment for spinal or lower extremity problems or had undergone surgery within the last six months, as well as those with severe chronic illnesses or uncontrolled conditions (e.g., hypertension, cancer), will be excluded from the study.

Primary outcomes:
measure: Fall Risk
timeFrame: Through study completion, an average of 5 months
measure: Fall Risk
timeFrame: Through study completion, an average of 5 months
measure: Vibration Sense
timeFrame: Through study completion, an average of 5 months
measure: Proprioception Sense
timeFrame: Through study completion, an average of 5 months
measure: Isometric Muscle Strength
timeFrame: Through study completion, an average of 5 months
measure: Static Balance
timeFrame: Through study completion, an average of 5 months
measure: Reaction Time
timeFrame: Through study completion, an average of 5 months
measure: Postural Stability
timeFrame: Through study completion, an average of 5 months
Secondary outcomes:
Other outcomes:
Locations:
city: Mersin
country: Turkey
facility: Cyprus International University
state: Haspolat
Study officials:
affiliation: Cyprus International University
name: Mehmet Miçooğulları, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Park H, Kim KJ, Komatsu T, Park SK, Mutoh Y. Effect of combined exercise training on bone, body balance, and gait ability: a randomized controlled study in community-dwelling elderly women. J Bone Miner Metab. 2008;26(3):254-9. doi: 10.1007/s00774-007-0819-z. Epub 2008 May 11.
citation: Sherrington C, Lord SR, Finch CF. Physical activity interventions to prevent falls among older people: update of the evidence. J Sci Med Sport. 2004 Apr;7(1 Suppl):43-51. doi: 10.1016/s1440-2440(04)80277-9.
citation: Loureiro V, Gomes M, Loureiro N, Aibar-Almazan A, Hita-Contreras F. Multifactorial Programs for Healthy Older Adults to Reduce Falls and Improve Physical Performance: Systematic Review. Int J Environ Res Public Health. 2021 Oct 15;18(20):10842. doi: 10.3390/ijerph182010842.
citation: Gillespie LD, Robertson MC, Gillespie WJ, Sherrington C, Gates S, Clemson LM, Lamb SE. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2012 Sep 12;2012(9):CD007146. doi: 10.1002/14651858.CD007146.pub3.
citation: Toledo DR, Barela JA. Sensory and motor differences between young and older adults: somatosensory contribution to postural control. Rev Bras Fisioter. 2010 May-Jun;14(3):267-75. English, Portuguese.
citation: He H, Luo C, Chang X, Shan Y, Cao W, Gong J, Klugah-Brown B, Bobes MA, Biswal B, Yao D. The Functional Integration in the Sensory-Motor System Predicts Aging in Healthy Older Adults. Front Aging Neurosci. 2017 Jan 5;8:306. doi: 10.3389/fnagi.2016.00306. eCollection 2016.