Clinical trial NCT05107180: cl[Nical Study of Succide Among Patient With Psychoactive Substance Use Disorders
Official title: cl[Nical Study of Succide Among Patient With Psychoactive Substance Use Disorders
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Substance Use Disorders
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2021-11-04
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patient with substance use disorder

Brief summary: detect risk of suicide among patient with substance use disorder

Detailed description: Substance use disorder (or drug addiction) is a neuropsychiatric disorder characterized by recurring desire to continue taking the drug despite harmful consequences. Substance use disorders are a major risk factor for suicide Suicide is a leading cause of premature death in young adults. Data from the World Health Organization indicate that the rate of completed suicide for the world's population is 16 per 100,000 inhabitants, which means that each year more than a million people in the world commit suicide. Suicide attempts are five to twenty times more common than the completed suicide.Based on the data from the research community, approximately 5% of adults attempts suicide at least once in their lifetime .

Mental health problems are the most common and best explored risk factor associated suicidal ideas, suicide attempts and completed suicide. About 90% of all people who commit suicide met the diagnostic criteria for one or more psychiatric disorders . People who use alcohol and/or drugs or are dependent on them, attempting suicide nearly six times more often than people who do not use these substances. The rate of completed suicide among addicts is 2 to 3 times higher than among the males who are not addictst, while in a few cases the manner in which the suicide is attempted is not directly related to drugs . Although there is a correlation between the disorder caused by the use of substances and suicidal behavior, a large number of addicts will never attempt suicide. It is therefore important to identify those individuals with the disorder caused by the use of substances that may be at higher risk for suicide .

Many risk factors for suicide in the general population also apply to drug addicts. The older drug addicts are at higher risk for attempts and suicides than younger addicts Another very important fact when it comes to suicide attempts is the drug used. It is known that heroin and sedatives are substances with which suicide attempts suicide are most often made, while other drugs are less characteristic .

Eligibility criteria: Inclusion Criteria:

* Patients fulfilling diagnostic criteria of substance use disorder

  1. social impairment
  2. impaired control
  3. risky use
  4. pharmacological indicators (tolerance and withdrawal).

Exclusion Criteria:

* Patient with other psychatric disorders ex schizophrenia, mood disorder

Primary outcomes:
measure: Prevelance of suicide and suicide tendancy in patients with substance use disorders.
timeFrame: 6 months
measure: Detect risk factors for suicide and in patients with substance use disorder.
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Yuodelis-Flores C, Ries RK. Addiction and suicide: A review. Am J Addict. 2015 Mar;24(2):98-104. doi: 10.1111/ajad.12185. Epub 2015 Feb 2.
citation: Webster LR. Risk Factors for Opioid-Use Disorder and Overdose. Anesth Analg. 2017 Nov;125(5):1741-1748. doi: 10.1213/ANE.0000000000002496.