Clinical trial NCT05539495: Exercise Recovery From Persistent Depression: A Thematic Analysis
Official title: Exercise Recovery From Persistent Major Depression in a UK Tertiary Care Centre: A Qualitative Thematic Analysis of Barriers and Drivers to Participation in a Structured Group Exercise Program
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Major Depressive Disorder
Depression Moderate
Depression Severe
Keywords: Exercise
Barriers
Facilitators
Lead sponsor: University of Nottingham
Sponsor class: OTHER
Collaborators: name: Nottinghamshire Healthcare NHS Trust
First posted: 2022-09-14
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with persistent major depression who have at least agreed to referral to the Exercise Recovery Group at the Nottingham Specialist Depression Service within the previous 24 months

Brief summary: Depression is a leading cause of disability worldwide and poses a large economic burden in the UK. There is evidence that exercise is beneficial in the management of depression and NICE now recommends group exercise programs as a treatment for people with mild and moderate-severe depression. Research shows that patients with severe depression are less likely to engage in exercise than patients with mild to moderate depression. There is little evidence, however, on the barriers and drivers to participation in such programs experienced by patients with depression; leading to uncertainty in the most effective way to implement these programs. We aim to analyse accounts of patients who have been referred to or participated in the Exercise Recovery Group (ERG), a group exercise program at the Nottingham Specialist Depression Service (NSDS). The NSDS is a tertiary unit where referred patients have suffered moderate-severe, persistent clinical depression. Eligible participants will be patients with persistent major depression who have agreed to referral to the ERG at the NSDS and who are able to provide informed consent. Participants will undergo a one-off 60 minute meeting via MS Teams, including an in-depth semi-structured interview on their experience as well as self-completion questionnaires assessing demographics, depression, anxiety and shame. Transcripts of the interviews will be subject to qualitative thematic analysis addressing questions on barriers and drivers of exercise treatment in depression; and the perceived impact of an exercise group on the individual participating. Themes will be developed to give an account of these questions, supported by anonymised quotes from the transcripts. The questionnaire data (on demographics, depression, anxiety, shame) will be used to characterise the group, in order to help assess directness of the evidence provided for other clinical populations; ultimately helping clinicians to implement exercise groups for depression that are acceptable for patients.


Eligibility criteria: Inclusion Criteria:

* Patients with persistent major depression
* Patients who have at least agreed to referral to the Exercise Recovery Group within the previous 24 months
* Patients who are able to provide informed consent.

Exclusion Criteria:

* Patients with a main diagnosis of Bipolar Disorder.
* Patients who cannot speak fluently in English.
* Patients without an email account or access to an electronic device that could be used for the MS Teams meeting.
* Patients who are younger than 18-years-old. There is no upper age limit.

Primary outcomes:
measure: What are the barriers and drivers to using exercise as a treatment for persistent major depression? via thematic analysis of semi-structured interview.
timeFrame: 12 months
Secondary outcomes:
measure: How do these barriers and drivers operate at different stages of 'participation', including contemplation of group participation; and within group participation? via thematic analysis of semi-structured interview.
timeFrame: 12 months
measure: What is the perceived impact of an exercise group on the individual participating, including positive and negative effects? via thematic analysis of semi-structured interview.
timeFrame: 12 months
Other outcomes:
Locations:
city: Nottingham
country: United Kingdom
facility: Nottinghamshire Healthcare NHS Foundation Trust
state: Nottinghamshire
Study officials:
affiliation: University of Nottingham
name: Neil Nixon, BSc,MMedSci,MBBS,DM,FRCPsych
role: PRINCIPAL_INVESTIGATOR
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