Clinical trial NCT04822155: The Social Gradient of Urban Noise Pollution and Its Effect on Pediatric and Adult Health
Official title: The Social Gradient of Urban Noise Pollution and Its Effect on Pediatric and Adult Health
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Noise Exposure
Environmental Exposure
Health Behavior
Lead sponsor: University of Pennsylvania
Sponsor class: OTHER
First posted: 2021-03-30
Enrollment: 0
Sex: ALL
Minimum age (years): 11
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Our population includes adult (18 years and older) and adolescent (11-17 years) subjects living in target Philadelphia neighborhoods determined by noise profiles (AIM 1).

Brief summary: The investigators pilot test an intervention to understand the spatial-temporal distribution of aggregated environmental noise exposure in Philadelphia and its impact on health.

Detailed description: Noise pollution - sound created by human activities considered harmful to health - represents an oft- cited public concern, yet has taken a back seat to other environmental hazards. A limited number of observational studies demonstrate that chronic environmental noise exposure is associated with poor outcomes in adults and children, including cardiovascular disease, poor mental health, impaired sleep, and reduced cognitive performance in children. Further investigation and direct measurement at a community-level is needed to not only better understand the spatial-temporal distribution of aggregated environmental noise exposure and its impact on health, but also to lay the groundwork to develop and evaluate needed noise-reducing interventions.

The broad objective of this pilot proposal is to examine the social gradient of noise at a micro-spatial level in Philadelphia and evaluate its impact on the health of pediatric and adult local residents. Our multi-disciplinary team uniquely combines emerging digital and remote-sensing technologies, and expertise in place- based interventions to achieve the following specific aims: (AIM 1) Document the spatial-temporal distribution of environmental noise exposure across 24 Philadelphia neighborhoods with low, medium, and high socioeconomic status (SES), and (AIM 2) Explore the feasibility of evaluating the relationship between noise exposure and biometric health data - including sleep quality, cardiovascular metrics, and neurobehavioral profiles in pediatric and adult participants.

Eligibility criteria: Inclusion Criteria:

* Residents living within 0.25 miles of the location of an external sound device
* Adults 18 years and older
* Children between 11-17 years of age
* Able to understand and respond to an oral interview in English

Exclusion Criteria:

* Unwilling to wear an Actigraphy device
* Adults unwilling to take blood pressure

Primary outcomes:
measure: Environmental noise measurement of 24 Philadelphia neighborhoods using outdoor remote monitoring via International Electrotechnical Commission (IEC)
timeFrame: 30 days
measure: Measures of feasibility
timeFrame: 14 days
measure: Measures of acceptability
timeFrame: 14 days
Secondary outcomes:
measure: Sleep duration using an Actigraphy device (adults and pediatric)
timeFrame: 14 days
measure: Sleep quality using an Actigraphy device (adults and pediatric)
timeFrame: 14 days
measure: Cardiovascular health (adults only)
timeFrame: 14 days
measure: Neurobehavioral measures (pediatric): BRIEF-II
timeFrame: 14 days
measure: Neurobehavioral measures (pediatric): CBCL
timeFrame: 14 days
measure: Neurobehavioral measures (adults): BRIEF-A
timeFrame: 14 days
measure: Neurobehavioral measures (adults): ABCL
timeFrame: 14 days
Other outcomes:
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