louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02919514: Effect of Surfaces on Fall in Elderly
Official title: Effects of Physical Training on Hard, Sand and Soft Surfaces on Functional Ability and Incidence of Falls in Elderly With or Without History of Falls
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Falls, Accidental
Aging
Keywords: fall prevention
Aging
surfaces
Lead sponsor: Khon Kaen University
Sponsor class: OTHER
First posted: 2016-09-29
Enrollment: 120
Sex: ALL
Minimum age (years): 60
Maximum age (years): 99
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: To investigate the effects of Thai dance exercises over 6 weeks on functional outcomes and incidence of fall in community-dwelling older individuals.

To compare effects of exercise training on hard, soft and sand surfaces in community-dwelling older individuals


Eligibility criteria: Inclusion Criteria:

* age at least 60 yr old
* fall

Exclusion Criteria:

* having pain (VAS \>5)

Primary outcomes:
measure: 10-meter walk test (10MWT)
timeFrame: 0,3 and 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Multiple Locations
country: Thailand
facility: Khon Kaen University
state: Khon Kaen
Study officials:
affiliation: School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand.
name: Sugalya Amatachaya, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04597814: The Relationship Between the Tumor Markers and Interstitial Lung Disease
Official title: The Relationship Between the Tumor Markers and Interstitial Lung Disease
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: the Relationship Between the Tumor Markers and Interstitial Lung Disease Patients
Keywords: carcinoembryonic antigen
carbohydrate antigen 19-9
carbohydrate antigen 125
Lead sponsor: The First Affiliated Hospital of Guangzhou Medical University
Sponsor class: OTHER
First posted: 2020-10-22
Enrollment: 13
Sex: ALL
Minimum age (years): 20
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: lung disease patients for lung transplantation

Brief summary: The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.

This study was undertaken to investigate the source of these serum tumor markers.

Detailed description: The serum levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 are often increased in interstitial lung disease patients.

This study was undertaken to investigate the source of these serum tumor markers.We hypothesis that these tumor markers are released from the lung.

The broncholveolr lvge fluid levels of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), CA125 were measured in the interstitial lung disease patients before lung transplantation. The immunohistochemical test was performed in the specimen lung after lung transplantation.

Eligibility criteria: Inclusion Criteria

1.Interstitial lung disease patients for lung transplantation

-

Exclusion Criteria:

1. tumor
2. Interstitial lung disease patients could not be performed by lung transplantation

Primary outcomes:
measure: serum levels of carcinoembryonic antigen (CEA)
timeFrame: 6months
measure: serum levels of carbohydrate antigen 19-9 (CA19-9)
timeFrame: 6months
measure: serum levels of carbohydrate antigen 125(CA125)
timeFrame: 6months
measure: The alveolar lavage fluid levels of carcinoembryonic antigen (CEA)
timeFrame: 1 week
measure: The alveolar lavage fluid levels of carbohydrate antigen 19-9 (CA19-9)
timeFrame: 1 week
measure: The alveolar lavage fluid levels of carbohydrate antigen 125
timeFrame: 1 week
measure: The lung tissue levels of carcinoembryonic antigen (CEA)
timeFrame: 1 week
measure: The lung tissue levels of carbohydrate antigen 19-9 (CA19-9)
timeFrame: 1 week
measure: The lung tissue levels of carbohydrate antigen 125
timeFrame: 1 week
Secondary outcomes:
Other outcomes:
Locations:
city: Guangzhou
country: China
facility: The First Affiliated Hospital of Guangzhou Medical University
state: Guangdong
Study officials:
References:
Clinical trial NCT02789514: A Survey of the Indications for Esophagogastroduodenoscopy (EGD) in Children's Hospital of Fudan University
Official title: A Survey of the Indications for Esophagogastroduodenoscopy (EGD) in Children's Hospital of Fudan University
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Digestive System Abnormalities
Keywords: esophagogastroduodenoscopy
paediatric
Lead sponsor: Children's Hospital of Fudan University
Sponsor class: OTHER
First posted: 2016-06-03
Enrollment: 1303
Sex: ALL
Minimum age (years): 1
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All of the patients need esophagogastroduodenoscopic procedures

Brief summary: Esophagogastroduodenoscopy (EGD) become more and more common in diagnosing gastroenterology diseases. The investigators want to find which symptoms can support for positive endoscopic findings.

Detailed description: Esophagogastroduodenoscopy (EGD) become more and more common in diagnosing gastroenterology diseases. And there are indications for EGD. Here, investigators want to find which symptoms can strongly support for positive endoscopy findings. So, investigators design the study to record the symptoms in detail and diagnosis, and then analysis symptoms and the rate of endoscopic findings.

Eligibility criteria: Inclusion Criteria:

* All of the patients need esophagogastroduodenoscopic procedures

Exclusion Criteria:

* None

Primary outcomes:
measure: Questionnaires about the indications for esophagogastroduodenoscopic procedures were collected
timeFrame: May, 2016-August, 2016
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Children's Hospital of Fudan University
name: Ying Huang, doctor
role: STUDY_DIRECTOR
References:
Clinical trial NCT00931814: Effects of Exercise on Depression Symptoms, Physical Function, and Quality of Life in Community-Dwelling Elderly
Official title: Effects of Exercise on Depression Symptoms, Physical Function, and Quality of Life in Community-Dwelling Elderly
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy Elderly
Keywords: Depression
physical function
Quality of life
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
First posted: 2009-07-02
Enrollment: 50
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study was to investigate the effects of 8-week exercise training on depression symptoms, physical functions, and quality of life in the community-dwelling elderly.


Eligibility criteria: Inclusion Criteria:

* elderly subjects living in the community aged 65 years or older, sedentary lifestyle

Exclusion Criteria:

* cancer, major neuromuscular disease, respiratory or cardiovascular disease which might affect exercise
* post myocardial infarction or major surgery in the previous year
* psychological disease

Primary outcomes:
measure: Taiwanese Geriatric Depression Scale (TGDS), Mini-Mental State Examination (MMSE), Groningen Activity Restriction Scale (GARS)
timeFrame: 8 weeks
Secondary outcomes:
measure: Short-form 36 (SF-36)
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: National Taiwan University
Study officials:
References:
Clinical trial NCT04648514: Radiographic Evaluation of Bone Height Gain With Dental Implant Placed Simultaneously With Closed Sinus Lifting Using Hydraulic Lift Technique Versus Summers' Osteotome Technique in Posterior Edentulous Maxilla (RCT)
Official title: Radiographic Evaluation of Bone Height Gain With Dental Implant Placed Simultaneously With Closed Sinus Lifting Using Hydraulic Lift Technique Versus Summers' Osteotome Technique in Posterior Edentulous Maxilla (Randomized Clinical Trial)
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Evaluations, Diagnostic Self
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2020-12-01
Enrollment: 32
Sex: ALL
Minimum age (years): 20
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Radiographic evaluation of bone height gain with dental implant placed simultaneously with closed sinus lifting using hydraulic lift technique versus summers' osteotome technique in posterior edentulous maxilla (RCT)

Detailed description: Evaluation will be done on the amount of bone height gain radiographically (using both panorama and CBCT) after placement of the dental implant simultaneously with closed sinus lifting using hydraulic lift technique versus summers' osteotome technique in patients with posterior edentulous maxilla (Randomized Clinical Trial)

Eligibility criteria: Inclusion Criteria:

* Edentulous patients in the maxillary posterior region .
* Patients in need to fixed restorations in posterior region .
* Patients with a healthy systemic conditions.(Apparently medically free)
* Patients with adequate inter-arch space for placement of the prosthetic part of the implant .
* Patients who had approximately 5-8 mm of available bone height between crest of bone and floor of sinus
* Both sexes.
* Patients with Good oral hygiene
* Patients more than 20 years old
* Cooperative and motivated patients

Exclusion Criteria:

* Patients with local pathological defects related to posterior maxilla .
* Heavy smokers.
* Abnormal habits that may alter results such as alcoholism or parafuctional habits .
* Patients with systemic diseases that may affect normal healing.
* Patients with psychiatric problem
* Patients with history of recent radiation therapy to the head and neck area .
* Patients with aggressive periodontitis .

Primary outcomes:
measure: Amount of bone height change
timeFrame: 6 months
Secondary outcomes:
measure: Patient satisfaction numerical questionnaire
timeFrame: 6 months
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Cairo university
Study officials:
affiliation: Assoc.professor of oral and maxillofacial surgery
name: Hassan Abdelghany, PHD
role: STUDY_DIRECTOR
References:
Clinical trial NCT05653414: Interest of a Short Early Psychological Care in Women With Miscarriage
Official title: Interest of a Short Early Psychological Care in Women With Miscarriage: a Controlled Randomized Study
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Miscarriage
Keywords: Miscarriage
Psychological care
Anxiety
Depression
Post traumatic stress disorder
Lead sponsor: Université de Reims Champagne-Ardenne
Sponsor class: OTHER
First posted: 2022-12-16
Enrollment: 932
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Miscarriage is a very common complication of pregnancy, accounting for 15.3% (95% CI 12.5-18.7%) of diagnosed pregnancies. Miscarriage would affect one in ten women during her lifetime. Worldwide, 23 million miscarriages occur annually.

Because of its frequency, miscarriage isoften considered as trivial event by caregivers. Still, miscarriage can be a traumatic event. Literature is consistent on the psychological morbidity associated with miscarriage. Anxiety, depression, post-traumatic stress have been studied in women after miscarriage. Cohort studies and clinical trials suggest that psychological and supportive interventions performed in women after miscarriage may improve women's psychological well-being and reduce miscarriage complications in subsequent pregnancies. However, to date, the literature is considered insufficient on the psychological care of women after a miscarriage.

Detailed description: The aim of the study will be to evaluate the interest of a short early psychological care in women with miscarriage.

Eligibility criteria: Inclusion Criteria:

* women with an early miscarriage (defined by a spontaneous termination of pregnancy before the 14th week of amenorrhea)
* women aged more than 18
* women agreeing to participate in the study (signing the informed consent form).

Exclusion Criteria:

* ectopic pregnancy
* molar pregnancy
* women with recurrent miscarriages
* women less than 18

Primary outcomes:
measure: anxiety
timeFrame: Month 3
Secondary outcomes:
measure: depression
timeFrame: month 3
measure: anxiety
timeFrame: month 6
measure: depression
timeFrame: month 6
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT01713114: Effects of a Variety of Meals on Satiety
Official title: A Randomized, Controlled Crossover Trial to Assess the Effects of Varying Meals on Satiety
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Focus of the Study is Satiety
Lead sponsor: The Hillshire Brands Company
Sponsor class: INDUSTRY
Collaborators: name: Biofortis Clinical Research, Inc.
First posted: 2012-10-24
Enrollment: 38
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER

Brief summary: The primary objective of this study is to assess the acute effects of different meals on satiety. It is hypothesized that a lower carbohydrate meal will result in greater feelings of satiety and reduced food intake at a subsequent meal compared to the higher-carbohydrate or meal skipping conditions.

Detailed description: Satiety refers to feelings of fullness or lack of desire to eat following consumption of a food or meal. A number of dietary factors have been shown to influence satiety, including food volume, food weight, energy density, food palatability, and certain food ingredients. The nutritional composition of a meal appears to also play a significant role in an individual's feelings of satiety and ability to stay full until the next meal.

Eligibility criteria: Inclusion Criteria:

* premenopausal Females
* Ages 18-55
* BMI between 18.5-29.9
* Willing to maintain weight throughout study period

Exclusion Criteria:

* Subject has a history of any surgical intervention for the treatment of obesity
* Recent history or use of weight loss drugs, herbal supplements or on a dieting program or trying to loose weight
* Gains or loses more than 6 pounds over the study period
* Current or history of an eating disorder
* Restrained eater
* Excludes any foods or meals from their diet
* History or presence of clinically important cardiac, renal, hepatic, endocrine, pulmonary, gastrointestinal, biliary, pancreatic or neurologic disorders
* Signs of an infection
* Heavy user of caffeine or alcohol
* Unconventional sleep patterns (e.g. works 3rd shift)
* Subject is pregnant or planning to become pregnant during the study period

Primary outcomes:
measure: Composite Area under the Curve - Visual Analog Scale
timeFrame: Acute - up to 4 hrs
Secondary outcomes:
measure: Individual satiety measures - Area under the curve
timeFrame: 4 hrs
Other outcomes:
measure: Differences between test conditions in food intake, energy intake and areas under the curve.
timeFrame: 4 hrs
Locations:
city: Addison
country: United States
facility: Biofortis Clinical Research
state: Illinois
Study officials:
References:
citation: Rains TM, Leidy HJ, Sanoshy KD, Lawless AL, Maki KC. A randomized, controlled, crossover trial to assess the acute appetitive and metabolic effects of sausage and egg-based convenience breakfast meals in overweight premenopausal women. Nutr J. 2015 Feb 10;14:17. doi: 10.1186/s12937-015-0002-7.
Clinical trial NCT00632814: Russian Kogenate Pediatric Study
Official title: A Prospective Study to Evaluate the Effect of rFVIII-FS in Different Prophylactic Regimens on Bleeding Events Frequency and Development of Arthropathy in Previously Treated and Minimally Treated Hemophilia A Pediatric Population.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Hemophilia A
Keywords: Kogenate,
Children,
Factor VIII,
Hemophilia A,
Prophylactic
Lead sponsor: Bayer
Sponsor class: INDUSTRY
First posted: 2008-03-11
Enrollment: 32
Sex: MALE
Minimum age (years): 1
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A prospective study to evaluate the effect of rFVIII-FS in different prophylactic regimens on bleeding events frequency and development of arthropathy in Previously Treated and Minimally treated Hemophilia A pediatric population.


Eligibility criteria: Inclusion Criteria:

* Male
* Severe hemophilia A or moderate hemophilia A
* 1-12 years of age
* Requiring treatment with FVIII

Exclusion Criteria:

* Current or prior inhibitor or familial antecedents of inhibitor
* Surgery required during the study (9 months)
* Positive for HIV

Primary outcomes:
measure: Percentage of Participants With Less Than 2 Joint Bleeds During the 9-month Treatment Period
timeFrame: Up to 9 months
Secondary outcomes:
measure: Number of Bleeds Per Participant During the 9-month Treatment Period
timeFrame: Up to 9 months
measure: Number of Participants With Bleeding Events During the 9-month Treatment Period
timeFrame: Up to 9 months
measure: Number of Participants With Joint Bleeds During the 9-month Treatment Period
timeFrame: Up to 9 months
measure: Number of Participants in Each Group at the End of the Study
timeFrame: Up to 9 months
measure: Actual Monthly rFVIII-FS Consumption
timeFrame: Up to 9 months
measure: Change From Baseline in Stockholm Hemophilia Joint Score at 9 Months of Treatment
timeFrame: baseline and 9 months
measure: Haemo-QoL Standardized Total Score at 9 Months of Treatment (Completed by Participants in the Total Group)
timeFrame: 9 months
measure: Haemo-QoL Standardized Total Score (Completed by Parents/Caregivers in the Total Group) at 9 Months of Treatment
timeFrame: 9 months
Other outcomes:
Locations:
city: Ekaterinburg
country: Russian Federation
city: Kirov
country: Russian Federation
city: Moscow
country: Russian Federation
city: St. Petersburg
country: Russian Federation
Study officials:
affiliation: Bayer
name: Bayer Study Director
role: STUDY_DIRECTOR
References:
citation: V.V. Vdovin, T.A. Andreeva, T.A. Chernova, F.G. Perina, E.E.M. Shiller, P.V. Svirin, M. Maas Enriquez, and S. Rauchensteiner. Prophylaxis with Once, Twice or Three-Times Weekly Dosing of rFVIII-FS Prevents Joint Bleeds in a Previously Treated Pediatric Population with Moderate/Severe Hemophilia A. Journal of Coagulation Disorders 2011; 3:(1). October 2011
Clinical trial NCT05245214: Muscle Analyze In Patient With Disc Herniation
Official title: Comprehensive Analysis Of Muscle Wasting In Disc Herniation
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Disk Herniated Lumbar
Lead sponsor: Karamanoğlu Mehmetbey University
Sponsor class: OTHER
First posted: 2022-02-17
Enrollment: 330
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients without disc herniation, severe disc degeneration and spondylolisthesis were also withdrawn from the System and included in the control group. 80 individuals with aged between 20-70 years included control group.

Brief summary: This study which was planned to investigate the factors affecting m. erector spinae (ES), m. multifidus (MF), m. psoas major (PM) and m. quadratus lumborum (QL), which stabilize the lumbar region in the case of disc herniation. In this study, the effects of disc herniation, herniation severity, age, and spinal biomechanics were investigated.

Detailed description: This study was carried out on 330 individuals with and without lumbar disc herniation. All individuals were divided into 3 groups according to their age. The inclusion criteria: Having only disc degeneration and not having any other neurological or orthopedic disease. Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Eligibility criteria: Inclusion Criteria:

* Having only disc degeneration and not having any other neurological or orthopedic disease. Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Exclusion Criteria:

* Patients who had previous spinal surgery, patients with lumbar scoliosis, spondylolisthesis or structural defect in the sacrum were excluded from the study.

Primary outcomes:
measure: Muscle cross-area
timeFrame: 1 Month
Secondary outcomes:
measure: Lumbar Biomechanic
timeFrame: 1 Month
Other outcomes:
Locations:
city: Karaman
country: Turkey
facility: Karamanoğlu Mehmetbey University
Study officials:
affiliation: Karamanoğlu Mehmetbey Üniversitesi
name: Ayşenur Gökşen, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Sun D, Liu P, Cheng J, Ma Z, Liu J, Qin T. Correlation between intervertebral disc degeneration, paraspinal muscle atrophy, and lumbar facet joints degeneration in patients with lumbar disc herniation. BMC Musculoskelet Disord. 2017 Apr 20;18(1):167. doi: 10.1186/s12891-017-1522-4.