Clinical trial NCT04567914: Ultrasonographic Evaluation of Abdominal Muscle Thickness Symmetry and Correlation With Pulmonary Function
Official title: Ultrasonographic Evaluation of Abdominal Muscle Thickness Symmetry and Correlation With Pulmonary Function Test in Adolescent Idiopathic Scoliosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Muscle Physiology
Adolescent Idiopathic Scoliosis
Keywords: Abdominal muscle
Cobb angle
Imbalance
Spirometry
Ultrasonography
Lead sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sponsor class: OTHER_GOV
First posted: 2020-09-29
Enrollment: 80
Sex: ALL
Minimum age (years): 10
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: 10-18 years old patient with AIS diagnosis 10-18 years old healthy adolescent volunteer

Brief summary: We aimed in this study:

1. To compare the ultrasonographic measurements of the abdominal muscles thickness symmetry in patients with adolescent idiopathic scoliosis (AIS) and adolescent healthy individuals
2. To investigate the effect of measured thickness and symmetry on pulmonary function test.

Detailed description: This cross-sectional,case-control clinical study included 40 patients diagnosed with AIS and 40 age and gender -matched healthy individuals. AIS group was evaluated for localization of curvature and degree of curvature. Ultrasonographic measurements and were performed of bilaterally abdominal muscle thickness in both groups. Spirometry evaluation was performed in both groups. Intragroup and intergroup data were compared.

Eligibility criteria: Inclusion Criteria:

* Cobb angle over 10 degrees in radiological evaluation
* Between the ages of 10-18 and diagnosed with AIS by a specialist physiatrist

Exclusion Criteria:

* History of previous spinal surgery
* Patients using brace
* Those with any diagnosis of scoliosis other than AIS
* Those with a history of neuromuscular disease
* Previous spinal surgery
* Patients with neurological deficits on examination
* Patients with acute or chronic lung pathology
* Patients with abdominal surgery or injury
* Double curve or multiple curve
* Patients with concomitant chronic diseases
* The child's legal guardian does not allow it to take the tests

The control group:

* 10-18 volunteer adolescents without any health problems,
* In clinical evaluation: Healthy adolescents (without any asymmetric findings on three-way inspection, Adam's forward bend test and scoliometer) were included.

Primary outcomes:
measure: Abdominal Muscle Thickness Symmetry
timeFrame: during evaluation, an average of 45 minutes
Secondary outcomes:
measure: Spirometry
timeFrame: during evaluation, an average of 30 minutes
measure: Cobb angle
timeFrame: during evaluation, an average of 30 minutes
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Study officials:
affiliation: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
name: Muhsin DORAN, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
name: Kadriye Öneş, Assoc Prof
role: STUDY_CHAIR
References:
citation: Teyhen DS, Gill NW, Whittaker JL, Henry SM, Hides JA, Hodges P. Rehabilitative ultrasound imaging of the abdominal muscles. J Orthop Sports Phys Ther. 2007 Aug;37(8):450-66. doi: 10.2519/jospt.2007.2558.
citation: Newton PO, Faro FD, Gollogly S, Betz RR, Lenke LG, Lowe TG. Results of preoperative pulmonary function testing of adolescents with idiopathic scoliosis. A study of six hundred and thirty-one patients. J Bone Joint Surg Am. 2005 Sep;87(9):1937-46. doi: 10.2106/JBJS.D.02209.
citation: Linek P. Body Mass Normalization for Lateral Abdominal Muscle Thickness Measurements in Adolescent Athletes. J Ultrasound Med. 2017 Sep;36(9):1851-1857. doi: 10.1002/jum.14218. Epub 2017 May 15.
citation: Yang HS, Yoo JW, Lee BA, Choi CK, You JH. Inter-tester and intra-tester reliability of ultrasound imaging measurements of abdominal muscles in adolescents with and without idiopathic scoliosis: a case-controlled study. Biomed Mater Eng. 2014;24(1):453-8. doi: 10.3233/BME-130830.
citation: Dreimann M, Hoffmann M, Kossow K, Hitzl W, Meier O, Koller H. Scoliosis and chest cage deformity measures predicting impairments in pulmonary function: a cross-sectional study of 492 patients with scoliosis to improve the early identification of patients at risk. Spine (Phila Pa 1976). 2014 Nov 15;39(24):2024-33. doi: 10.1097/BRS.0000000000000601.