louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT05625295: Tele-dermatology Non-presential (TeleDermaSA)
Official title: Evaluation of the Implementation of Tele-dermatology, in Its Modality of Non-presential Inter-consultation, in the Province of Salamanca.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Teledermatology
Primary Care
Lead sponsor: Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Sponsor class: OTHER
First posted: 2022-11-22
Enrollment: 1000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: The unit of analysis will be the PNCIs performed in dermatology from Primary Care, registered in Medora software, with its corresponding photographic file, and its response in Jimena software of the dermatology service, from June 2021 to June 2022, one year. A random sample stratified by type of center (urban, semi-urban and rural) will be extracted.

A control group of face-to-face consultations will be used, in a similar number (500) obtained randomly, and also stratified by type of center, which will be used to compare the information from the NCIs.

Brief summary: The purpose of the study is to evaluate the implementation of the Non-Face-to-Face Interconsultation of dermatology since it began to be used in August 2020 until August 2022 in the province of Salamanca (Spain)

Detailed description: Design: cross-sectional descriptive study. Subjects: The unit of analysis will be the NPIs performed in dermatology since its implementation in August 2020 until the present time in the health area of Salamanca. To analyze the face-to-face consultations to analyze the differences. A random sample of 500 PNCIs and 500 face-to-face consultations will be extracted.

Measurements: To analyze the ICNP and face-to-face IC to dermatology registered in the computerized clinical history made in PC from Medora and registered in Jimena. To record the number of consultations, type of pathology referred, dermatology response time, discharges after assessment, face-to-face consultations required, delay time, treatment required, follow-up required or not, diagnostic coincidence, quality of the photographic image sent.

A differentiated analysis will be made according to the use or not of the dermatoscope, type of center (urban, semi-urban and rural), gender of the patients and age groups.

Eligibility criteria: Inclusion Criteria:

* The unit of analysis will be the PNCIs performed in dermatology from Primary Care, registered in Medora software, with its corresponding photographic file, and its response in Jimena software of the dermatology service, from June 2021 to June 2022, one year.

Exclusion Criteria:

-

Primary outcomes:
measure: Derivation rates per 10,000 h.
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Salamanca
country: Spain
facility: Centro de Salud La Alamedilla
Study officials:
affiliation: FUNDACION INFOSALUD
name: Luis G Garcia Ortiz, PhD
role: STUDY_DIRECTOR
References:
Clinical trial NCT02437695: Robot Assisted Radical Prostatecomy and Positional Injury
Official title: Robot Assisted Radical Prostatecomy and Positional Injury; 8 Years Survey
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Peripheral Nerve Injuries
Keywords: Robotic Surgical Procedures
Trendelenburg Position
Lead sponsor: Umraniye Education and Research Hospital
Sponsor class: OTHER_GOV
First posted: 2015-05-07
Enrollment: 450
Sex: MALE
Minimum age (years): 45
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patients undergoing robot-assisted radical prostatectomy (RARP) for prostate diagnosis.

Brief summary: Although a condition for surgery, robotic interventions applied with steep Trendelenburg-lithotomy (ST-L) position may cause positional injury and peripheral neuropathy if good position is not achieved on the operating table. This study will be a 7-year retrospective examination of postoperative positional injury (PPI) in patients undergoing robot-assisted radical prostatectomy (RARP) for prostate diagnosis.

Detailed description: Patients who underwent RARP between 2008-2014 will be evaluate. Patients with known peripheral neuropathy, lumbar-cervical discopathy, or history of orthopaedic surgery or trauma will exclude. The demographic data of patients, ASA, Charlson Comorbidity Index (CMI), Body Mass Index (BMI), operating time (OT) and Trendelenburg time (TT) will obtain from patient records. Patients will be questioned as to whether or not PPI had developed, if so, in which extremity, in what form (sensory-motor), duration, whether or not a doctor had been consulted, if so, what treatment had been given and whether or not the PPI had continued.

Eligibility criteria: Inclusion Criteria:

* Patients undergoing robot-assisted radical prostatectomy (RARP) for prostate diagnosis.

Exclusion Criteria:

* Patients with known peripheral neuropathy,
* Lumbar-cervical discopathy,
* History of orthopaedic surgery or
* Trauma were excluded

Primary outcomes:
measure: retrospective examination of postoperative positional injury (PPI) in patients undergoing robot-assisted radical prostatectomy (RARP) for prostate diagnosis
timeFrame: 7 years
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Umraniye Training Hospital
Study officials:
affiliation: Unraniye training and research hospital
name: Nurten Bakan, MD
role: STUDY_CHAIR
References:
citation: Mills JT, Burris MB, Warburton DJ, Conaway MR, Schenkman NS, Krupski TL. Positioning injuries associated with robotic assisted urological surgery. J Urol. 2013 Aug;190(2):580-4. doi: 10.1016/j.juro.2013.02.3185. Epub 2013 Mar 1.
Clinical trial NCT04048655: Reversal of Neuromuscular Blockade During the General Anaesthesia
Official title: Reversal of Neuromuscular Blockade During the General Anaesthesia
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Neuromuscular Blockade
Keywords: neuromuscular blockade
neostigmine
muscle relaxation
train of four
rocuronium
Lead sponsor: Tampere University Hospital
Sponsor class: OTHER
First posted: 2019-08-07
Enrollment: 120
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Single group with same study protocol to asses the incidence of postrecovery relaxation
Primary purpose: TREATMENT

Brief summary: There are individual reports indicating that after the reversal of nondepolarizing neuromuscular blockade with neostigmine, some patients starts to relax spontaneously again after the tof ratio has already recovered to the safe level (\>90%).

The mechanism behind this in not well understood, and the incidence of the phenomenon is unclear. In this study the investigators try to determine the incidence of the aforementioned postrecovery relaxation.

Detailed description: There are individual reports indicating that after the reversal of nondepolarizing neuromuscular blockade with neostigmine, some patients start to relax spontaneously again after the tof ratio has already recovered to the safe level (90%). The mechanism behind this in not well understood and the incidence of the phenomenon is unclear.

The aim of this study is to monitor the reversal of rocuronium induced neuromuscular blockade with neostigmine. The neuromuscular blockade is monitored with train of four stimulations using electromyography. After the reversal agent is given and train of four ratio has recovered to the level of 90%, the neuromuscular blockade is monitored another 30min to see if tof ratio starts to spontaneously fall again under the 90%. If aforementioned postrecovery relaxation happens, the investigators are able to calculate the incidence of the phenomenon.

Eligibility criteria: Inclusion Criteria:

* Elective surgery requiring general anaesthesia
* Surgery is assumed to last more than 45 minutes
* Body mass index less than 35kg/ m²

Exclusion Criteria:

* Disease of central nervous system
* Trauma of central nervous system
* Disease affecting peripheral nervous system
* Medication affecting peripheral nervous system

Primary outcomes:
measure: Incidence of postrecovery relaxation
timeFrame: 30 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Tampere
country: Finland
facility: Tampere University Hospital
Study officials:
affiliation: Tampere University Hospital
name: Maija Kalliomäki, Docent
role: STUDY_DIRECTOR
affiliation: Tampere University Hospital
name: Jarno Salminen, Licenciate
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02853955: MitraClip® After Surgical Mitral Valve Repair
Official title: MitraClip® for the Treatment of Recurrent Severe Mitral Regurgitation After Surgical Mitral Valve Repair
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Mitral Regurgitation
Lead sponsor: LMU Klinikum
Sponsor class: OTHER
First posted: 2016-08-03
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 95
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patients treated with a MitraClip® after sMVR

Brief summary: Percutaneous edge-to-edge repair of the mitral valve has been shown to be a safe and effective alternative treatment option for selected patients at high risk for cardiac surgery. Patients with recurrent mitral regurgitation after surgical mitral valve repair (sMVR) are per se at increased risk for another cardiac surgery. The purpose of this multicenter retrospective analysis of patients treated with a MitraClip® after sMVR, is to evaluate the effectiveness and durability of this minimally invasive treatment option in this subset of patients.

Detailed description: In this multicenter retrospective analysis of MitraClip® cases after MVR the effectiveness and durability of this minimally invasive treatment option in this subset of patients will be evaluated.

Eligibility criteria: Inclusion Criteria:

* All patients with recurrent mitral regurgitation treated with a MitraClip®.

Exclusion Criteria:

* Patient with endocarditis,
* Patients with torn mitral valve ring.

Primary outcomes:
measure: Survival
timeFrame: 1 year
measure: MR (mitral regurgitation) grade after clip treatment
timeFrame: 1 year
Secondary outcomes:
measure: MR (mitral regurgitation) grade at latest follow up
timeFrame: 1 year
measure: NYHA status at latest follow up
timeFrame: 1 year
measure: Distance in 6 minute walk test at latest follow up
timeFrame: 1 year
measure: LVEF (left ventricular ejection fraction) at latest follow up
timeFrame: 1 year
measure: LVEDV (left ventricular enddiastolic volume) at latest follow up
timeFrame: 1 year
measure: LVEDD (lef ventricular enddiastolic diameter) at latest follow up
timeFrame: 1 year
measure: Mean mitral valve gradient
timeFrame: 1 year
measure: Procedural complications
timeFrame: index procedure
measure: Death, recurrent mitral regurgitation grade > 2, repeat intervention/operation of mitral valve
timeFrame: 1 year
measure: Clip success based on type of sMVR
timeFrame: index procedure
Other outcomes:
Locations:
city: Munich
country: Germany
facility: Munich University Hospital
state: Bavaria
Study officials:
affiliation: LMU Munich
name: Jörg Hausleiter, MD
role: STUDY_CHAIR
References:
Clinical trial NCT03763955: Effectiveness of MIRT on Hand and Finger Dexterity in PD Patients
Official title: Effectiveness of MIRT on Hand and Finger Dexterity in PD Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Parkinson Disease
Dexterity
Rehabilitation
Lead sponsor: Ospedale Generale Di Zona Moriggia-Pelascini
Sponsor class: OTHER
First posted: 2018-12-04
Enrollment: 482
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: Parkinsonian inpatients

Brief summary: Aims of the study are (1) to evaluate the effectiveness of a specific OT treatment aimed to enhance finger and hand dexterity and (2) its impact on daily living autonomy of PD patients.

Detailed description: Reduction in hand functionality and finger dexterity are significant, but often overlooked, symptoms of Parkinson's Disease (PD). They are strictly correlated with loss of patient's autonomy, due to their significant impact on Activities of Daily Living (ADL) and, consequently in patient's Quality of life (QoL). No studies investigated the effectiveness of a specific and functional-based Occupational Therapy (OT) treatment in improving hand functionality and finger dexterity in PD patients.

Aims of tthe study are to evaluate the effectiveness of a specific OT treatment aimed to enhance finger and hand dexterity and its impact on daily living autonomy of PD patients.

Retrospectively, 482 PD patients, hospitalized for a 4-week Multidisciplinary Intensive Rehabilitation Treatment (MIRT) between January 2015 and January 2018 were identified. All patients underwent 1h/day OT treatment. The outcome measure was the O'Connor finger dexterity test; secondary outcome measures were Minnesota dexterity test, UPDRS II and SPDDS scale. These measures were assessed at admission (T0) and discharge (T1).

Eligibility criteria: Inclusion Criteria:

* diagnosis of Parkinson's Disease

Exclusion Criteria:

* other neurological disease
* psychosis
* auditive or visual deficit

Primary outcomes:
measure: O'Connor Finger Dexterity Test
timeFrame: 4 weeks
Secondary outcomes:
measure: Minnesota Manual Dexterity Test
timeFrame: 4 weeks
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT02058355: Development and Evaluation of Effectiveness of an Internet-based Brief Intervention for Alcohol Use Among Brazilian College Students
Official title: Development and Evaluation of Effectiveness of an Internet-based Brief Intervention for Alcohol Use Among Brazilian College Students
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Alcohol Drinking
Lead sponsor: Federal University of São Paulo
Sponsor class: OTHER
First posted: 2014-02-10
Enrollment: 46142
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This project aims to develop and evaluate the effectiveness of an Personalized Normative Feedback (PNF) intervention via the internet, through a randomized clinical trial for alcohol consumption among Brazilian college students, as well as evaluating the most effective components of the PNF (normative and list of consequences). The sample is composed of college students aged between 18 and 30 years. Participants allocated into four different groups: control, full intervention (PNF), feedback with normative components (FN) and feedback with list of consequences (FLC). The investigators will use the dismantling design to study the most effective components. Participants will be followed-up at 1, 3 and 6 months.


Eligibility criteria: Inclusion Criteria:

* College students
* Age 18-30 years
* Alcohol Use during the last 3 months

Exclusion Criteria:

-

Primary outcomes:
measure: Alcohol Consumption
timeFrame: Last 3 Months
Secondary outcomes:
measure: Maximum Drinks
timeFrame: Last 3 months
measure: Frequency of Alcohol Use
timeFrame: Last 3 months
measure: Typical Number of Drinks
timeFrame: Last 3 months
measure: Number of Alcohol-related Consequences
timeFrame: Last 3 Months
Other outcomes:
Locations:
city: Sao Paulo
country: Brazil
facility: Federal University of Sao Paulo
Study officials:
References:
Clinical trial NCT06599255: One-Puncture Versus Multipoint Technique of Rectus Sheath Block With Transverse Abdominis Plane Block
Official title: One-Puncture Versus Multipoint Technique of Rectus Sheath Block With Transverse Abdominis Plane Block for Analgesia After Laparoscopic Cholecystectomy
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Laparoscopic Cholecystectomy
Lead sponsor: Zagazig University
Sponsor class: OTHER_GOV
First posted: 2024-09-19
Enrollment: 102
Sex: ALL
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: the purpose of this study is to compare of better postoperative analgesia following laparoscopic cholecystectomy using either one puncture rectus sheath block with transverse abdominis plane block or multipoint technique

Detailed description: after being informed about the study and potential risks. All patients giving written consent will be randomized by double blind manner into 3 groups each one containing 34In the One puncture \&amp;#34;O\&amp;#34; group (n= 34): The patient will receive one-puncture technique of RSB combined with TAPB.

In the Multipoint \&amp;#34;M \&amp;#34; group (n= 34): The patient will receive multipoint technique of RSB combined with TAPB.

In the Control \&amp;#34;C \&amp;#34; group (n=34 ): The patient will receive patient controlled analgesia\&amp;;PCA\&amp;

Eligibility criteria: Inclusion Criteria:

* Age: 18-45 years old.
* Sex: both sexes.
* Physical status: ASA I to III.
* Body mass index (BMI): 18- 30 kg/m2.
* Type of operations: elective laparoscopic cholecystectomy.
* Written informed consent from the patient.

Exclusion Criteria:

* Known hypersensitivity to lidocaine or bupivacaine.
* Opioid-dependent patients.
* Coagulation disorders or taking drugs affect surgical hemostasis.
* Patients with pre-existing neurological deficits.
* Uncooperative patient or with altered mental status.

Primary outcomes:
measure: The total postoperative opioid consumption in the first 24 hours.
timeFrame: 24 hours postoperative
Secondary outcomes:
measure: The block performance time
timeFrame: up to 5 minutes
measure: Onset of sensory block
timeFrame: up to 30 minutes
measure: The Numerical Pain Rating Scale
timeFrame: 24 hours postoperative
measure: Patient satisfaction
timeFrame: 24 hour postoperative
Other outcomes:
Locations:
city: Zagazig
country: Egypt
facility: Faculty of Medicine,Zagazig University
state: Elsharkia,, Egypt,
Study officials:
References:
Clinical trial NCT06009055: Effects of Remimazolam and Propofol on Anesthesia Induction
Official title: Effects of Remimazolam and Propofol on Heart Rate Variability in Type 2 Diabetes Patients During Anesthesia Induction
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Diabetes
Lead sponsor: Second Hospital of Shanxi Medical University
Sponsor class: OTHER
First posted: 2023-08-24
Enrollment: 80
Sex: ALL
Minimum age (years): 30
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The patients with diabetes who underwent laparoscopic cholecystectomy in the general surgery department of the Second Hospital of Shanxi Medical University were selected. The patients who were induced by remimazolam were included in the experimental group, and the patients who were induced by propofol were included in the control group. All the selected patients had no intimate relationship. The differences of blood pressure, heart rate and heart rate variability (HRV) between the experimental group and the control group were observed. According to the literature, it is speculated that the changes of blood pressure, heart rate and HRV indexes in the experimental group are smaller than those in the control group, and the difference is statistically significant.


Eligibility criteria: Inclusion Criteria:

* Diagnosed as type 2 diabetes according to the "Chinese Guidelines for the Prevention and Treatment of Type 2 diabetes 2020"
* ASA II or III

Exclusion Criteria:

* People who are allergic to Remimazolam
* It is estimated that patients with difficulty in tracheal intubation (poor head and neck mobility, history of airway surgery, history of OSAHS, nail to chin distance\<6cm, Malampati grade 3 and above, mouth opening\<2.5cm, obesity (BMI\>30kg · m-2), etc
* Hypertension (clinically diagnosed as hypertension)
* Patients with coronary heart disease (with typical symptoms of angina pectoris and exclusion of aortic valve disease, clear history of old myocardial infarction, clear history of acute myocardial infarction, coronary stenosis greater than or equal to 70% found by CAG)
* Patients with arrhythmia, heart failure, renal failure, and recently taking cardiovascular active drugs
* Endocrine diseases such as hyperthyroidism and pheochromocytoma that may affect the level of body hemodynamics
* Ketoacidosis and lactic acidosis
* Patients with long-term use of sedatives or antidepressants or a history of alcoholism or drug dependence
* Asthma or reactive airway disease
* Patients with myasthenia gravis and cognitive dysfunction cannot cooperate with this study

Primary outcomes:
measure: systolic pressure （SBP）
timeFrame: 24 hours
measure: diastolic pressure（DBP）
timeFrame: 24 hours
measure: heart rate
timeFrame: 24 hours
measure: Heart rate variability（HRV）
timeFrame: 24 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Taiyuan
country: China
facility: econd of Shanxi Medical University
state: Shanxi
Study officials:
References:
Clinical trial NCT06417255: Comparison Of The Effects Of Kinesiotape Application And Foam Roller Exercises
Official title: Comparison Of The Effects Of Kinesiotape Application And Foam Roller Exercises in Individuals With Chronic Low Back Pain
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Low Back Pain, Mechanical
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2024-05-16
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Low back pain is an important health problem that is common worldwide, with a lifetime prevalence of up to 80%.

Detailed description: Low back pain that lasts less than 6 weeks is called acute low back pain, if it continues for 6-12 weeks it is called subacute low back pain, and if it continues for more than 12 weeks it is called chronic low back pain. The majority of low back pain (97%) is of mechanical origin.

Eligibility criteria: Inclusion Criteria:

* Patients with chronic low back pain
* Individuals aged 18-60 years
* Patients without verbal communication barriers
* Patients without cognitive impairment (delirium, dementia, amnesia)

Exclusion Criteria:

* Exercise contraindication (uncontrolled medical conditions)
* Patients with previous spinal surgery
* Patients who develop an allergic reaction to the kinesiotape tape to be applied

Primary outcomes:
measure: Pressure Pain Measurement with Algometer
timeFrame: 6 weeks
measure: Pittsburgh Sleep Quality Scale
timeFrame: 6 weeks
measure: Schober Flexibility Test
timeFrame: 6 weeks
measure: The finger-to-floor distance
timeFrame: 6 weeks
measure: Tampa Kinesiophobia Fatigue Scale
timeFrame: 6 weeks
measure: Oswestry Scale
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Hazal GENÇ
state: None Selected
Study officials:
References: