Clinical trial NCT01391195: Effects of Low Level Laser Therapy (808nm) on Muscle Performance of Young Women Submitted to Physical Training
Official title: Effects of Low Level Laser Therapy (808nm) on Muscle Performance of Young Women Submitted to Physical Training
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Healthy
Keywords: low level laser therapy
muscle performance
fatigue index
endurance training
ventilatory threshold
VO2Max
VO2Peak
Lead sponsor: Universidade Federal de Sao Carlos
Sponsor class: OTHER
Collaborators: name: Conselho Nacional de Desenvolvimento Científico e Tecnológico
First posted: 2011-07-11
Enrollment: 45
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 28
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The study hypothesis is an increase in muscle performance and a higher aerobic adaptation of young women submitted to chronic endurance training program associated to low level laser therapy when compared to chronic aerobic training alone.

Detailed description: The study assessed women muscle performance in isokinetic dynamometry, ventilatory parameters such as ventilatory threshold, VO2Peak, VO2Max, Ventilation. Maximal load in cycle ergometer test (Balke's protocol), Borg Scale and Heart rate were assessed too.

Eligibility criteria: Inclusion Criteria:

* healthy young women volunteers
* women with a beginner or moderately trained pattern of physical activity
* body Mass Index (BMI) between 18 and 25kg/m2

Exclusion Criteria:

* previous injury to the femoral quadriceps or hamstrings muscles (within 6 months prior to study)
* osseous or articular disorder in the lower limbs
* cardiovascular system disorders or systemic disease

Primary outcomes:
measure: Fatigue Index of knee extensor muscles
timeFrame: nine weeks
measure: Ventilatory threshold
timeFrame: nine weeks
measure: VO2max
timeFrame: nine weeks
measure: VO2peak
timeFrame: nine weeks
measure: Maximum load of effort on cycle ergometer (Balke's protocol).
timeFrame: nine weeks
Secondary outcomes:
measure: Total work of knee extensor muscles
timeFrame: nine weeks
measure: Peak torque of knee extensor muscles
timeFrame: nine weeks
measure: Borg scale
timeFrame: nine weeks
measure: Heart rate
timeFrame: nine weeks
Other outcomes:
Locations:
city: São Carlos
country: Brazil
facility: Universidade Federal de Sao Carlos
state: São Paulo
Study officials:
affiliation: Universidade Federal de Sao Carlos
name: Wouber Hérickson B Vieira, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: Universidade Federal de Sao Carlos
name: Nivaldo A Parizotto, PhD
role: STUDY_DIRECTOR
affiliation: Universidade Federal de Sao Carlos
name: Cleber Ferraresi, Ms
role: PRINCIPAL_INVESTIGATOR
References:
citation: Ferraresi C, de Brito Oliveira T, de Oliveira Zafalon L, de Menezes Reiff RB, Baldissera V, de Andrade Perez SE, Matheucci Junior E, Parizotto NA. Effects of low level laser therapy (808 nm) on physical strength training in humans. Lasers Med Sci. 2011 May;26(3):349-58. doi: 10.1007/s10103-010-0855-0. Epub 2010 Nov 18.
citation: Leal Junior EC, Lopes-Martins RA, de Almeida P, Ramos L, Iversen VV, Bjordal JM. Effect of low-level laser therapy (GaAs 904 nm) in skeletal muscle fatigue and biochemical markers of muscle damage in rats. Eur J Appl Physiol. 2010 Apr;108(6):1083-8. doi: 10.1007/s00421-009-1321-1. Epub 2009 Dec 19.
citation: Lopes-Martins RA, Marcos RL, Leonardo PS, Prianti AC Jr, Muscara MN, Aimbire F, Frigo L, Iversen VV, Bjordal JM. Effect of low-level laser (Ga-Al-As 655 nm) on skeletal muscle fatigue induced by electrical stimulation in rats. J Appl Physiol (1985). 2006 Jul;101(1):283-8. doi: 10.1152/japplphysiol.01318.2005. Epub 2006 Apr 20.
citation: Baroni BM, Leal Junior EC, De Marchi T, Lopes AL, Salvador M, Vaz MA. Low level laser therapy before eccentric exercise reduces muscle damage markers in humans. Eur J Appl Physiol. 2010 Nov;110(4):789-96. doi: 10.1007/s00421-010-1562-z. Epub 2010 Jul 3.
citation: Baroni BM, Leal Junior EC, Geremia JM, Diefenthaeler F, Vaz MA. Effect of light-emitting diodes therapy (LEDT) on knee extensor muscle fatigue. Photomed Laser Surg. 2010 Oct;28(5):653-8. doi: 10.1089/pho.2009.2688. Epub 2010 Jul 13.
citation: Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Taufer D, Manfro DS, Rech M, Danna V, Grosselli D, Generosi RA, Marcos RL, Ramos L, Bjordal JM. Effect of 830 nm low-level laser therapy applied before high-intensity exercises on skeletal muscle recovery in athletes. Lasers Med Sci. 2009 Nov;24(6):857-63. doi: 10.1007/s10103-008-0633-4. Epub 2008 Dec 5.
citation: Leal Junior EC, Lopes-Martins RA, Vanin AA, Baroni BM, Grosselli D, De Marchi T, Iversen VV, Bjordal JM. Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans. Lasers Med Sci. 2009 May;24(3):425-31. doi: 10.1007/s10103-008-0592-9. Epub 2008 Jul 23.
citation: Leal Junior EC, Lopes-Martins RA, Dalan F, Ferrari M, Sbabo FM, Generosi RA, Baroni BM, Penna SC, Iversen VV, Bjordal JM. Effect of 655-nm low-level laser therapy on exercise-induced skeletal muscle fatigue in humans. Photomed Laser Surg. 2008 Oct;26(5):419-24. doi: 10.1089/pho.2007.2160.