Clinical trial NCT05821023: Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women
Official title: Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Breast Cancer Screening
Lead sponsor: Johns Hopkins University
Sponsor class: OTHER
Collaborators: name: University of Minnesota
name: Beth Israel Deaconess Medical Center
name: National Institute on Aging (NIA)
First posted: 2023-04-20
Enrollment: 4173
Sex: FEMALE
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This is an online survey experiment with data collection over 2 time points two weeks apart. This is Aim 2 of a three-aim R01 project; overall project goal is to better understand how messages from different sources interact to affect older women's breast cancer screening decisions. In this current project, the investigators propose to test the effect of combined exposure to a clinician message + a message from another source (i.e. family/friend or media) on older women's breast cancer screening beliefs, attitudes, and intentions.

Detailed description: In a two-wave national online survey experiment, the investigators will randomly assign 3,000 women 65 years or older without personal history of breast cancer to 6 groups, including two control groups and four experimental groups. The experimental groups will read a message at Time 1 (T1) that may be from either family/friend or the media followed by a second message from a clinician one to two weeks later at Time 2 (T2).

The clinician message will be directed at reducing over-screening, mentioning the harms of over-screening and supporting screening cessation. The investigators will systematically vary the non-clinician message to be either consistent with the clinician message (also mentions harms of over-screening and supports screening cessation) or conflicting (mentions benefits of screening, supports continued screening and opposes screening cessation). The investigators include a no-exposure control group (Group 1) where the participants read no message at either time point and will only be asked the assessment questions. The investigators also include a single exposure group that reads only the clinician message (Group 2).

Eligibility criteria: Inclusion Criteria:

* Part of an online survey panel called KnowledgePanel
* able to complete survey in English

Exclusion Criteria:

* Personal history of breast cancer

Primary outcomes:
measure: Support for stopping screening for a hypothetical patient in survey vignette assessed by score on a scale
timeFrame: Immediately after reading the assessment question
Secondary outcomes:
measure: Breast cancer screening intention for participant assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Breast cancer screening attitude on mammogram importance as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Breast cancer screening attitude on benefits of mammograms as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Breast cancer screening attitude on mammogram being worthwhile as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Message effectiveness toward thinking about getting a mammogram as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Message effectiveness toward finding out more about the benefits of a mammogram as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Message effectiveness toward finding out more about downsides of getting a mammogram as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
Other outcomes:
measure: Emotional reaction to message (annoyed) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Emotional reaction to message (interested) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Emotional reaction to message (worried) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Emotional reaction to message (reassured) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Open ended response to messages assessed by an open ended question
timeFrame: Immediately after reading the assessment question
measure: Potential unintended consequences (discouraged) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Potential unintended consequences (unpleasant) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Potential unintended consequences (concerned) as assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Number of participants aware of screening harms (guidelines) as assessed by yes/no question
timeFrame: immediately after reading the assessment question
measure: Number of participants aware of screening harms (treatments) assessed by yes/no question
timeFrame: Immediately after reading the assessment question
measure: Number of participants aware of screening harms (false alarm results) as assessed by yes/no question
timeFrame: Immediately after reading the assessment question
measure: Backlash after exposure to conflicting information (confusion) assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Backlash after exposure to conflicting information (indecision) assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Backlash after exposure to conflicting information (guidelines) assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Backlash after exposure to conflicting information (trust) assessed by score on a scale
timeFrame: Immediately after reading the assessment question
measure: Backlash after exposure to conflicting information (mixed feelings) assessed by score on a scale
timeFrame: Immediately after reading the assessment question
Locations:
city: Baltimore
country: United States
facility: Johns Hopkins University
state: Maryland
Study officials:
affiliation: Johns Hopkins School of Medicine
name: Nancy Schoenborn, MD
role: PRINCIPAL_INVESTIGATOR
References: