Clinical trial NCT06462846: Evaluation of Clinical Characteristics and Pathological Findings in Patients With Suspected Appendicitis
Official title: Evaluation of Demographic and Clinical Characteristics and Intraoperative and Pathological Findings in Patients With Suspected Appendicitis Who Underwent Appendectomy in 5 Azar Hospital in 2022
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Appendicitis
Keywords: Appendicitis
Appendectomy
Appendicitis diagnosis
Lead sponsor: Golestan University of Medical sciences
Sponsor class: OTHER
First posted: 2024-06-17
Enrollment: 291
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patents operated with the diagnosis of appendicitis in 5th azar medical center, in 2022

Brief summary: As we know, one of the most common reasons for people to visit health centers and hospitals (15%) is abdominal pain, and appendicitis is at the top of their diagnosis in the 2-4th decade of age, which in most cases For treatment, considering the patient's condition and the need for surgery, appendectomy is the first method. One of the things that helps us a lot in this area is the epidemiology and incidence of this disease in the target society, which sometimes varies in different regions. One of the things that can be checked in this disease is the age and gender of the person and its incidence in different age ranges.

Detailed description: appendicitis is one of the most important reasons for people to go to the hospital, and 15% of the visits to the hospital are for this reason, and sometimes patients end up undergoing appendectomy. The mortality rate of this disease is 0.2-1% among young people and 8% among people over 65 years old In some people, depending on the sex, age, pregnancy and related diseases and even the weight of the people, the location of the appendix is different and this issue is very important during surgery. Different positions of the appendix, such as retro-scapular, subhepatic, pelvic, etc., create different challenges during surgery, so investigating the possibilities of the location of the appendix is an important issue in the decision-making and preparation of the patient and the surgical team.

Also, laboratory criteria such as wbc, diff, plt, crp can also help in diagnosing this disease. In this project, in addition to the above, the chief complaints and accompanying symptoms of people have also been examined

Eligibility criteria: Inclusion Criteria:

* diagnosis of appendicitis
* appendectomy

Exclusion Criteria:

* Lack of required information in medical documents

Primary outcomes:
measure: The accuracy of imaging in determining the size of the appendix in patients with suspected appendicitis
timeFrame: One year
Secondary outcomes:
measure: correlation between CRP levels and pathologic findings in patients with suspected appendicitis
timeFrame: One year
measure: correlation between WBC measures and pathologic findings in patients with suspected appendicitis
timeFrame: One year
measure: sex distribution in patients with suspected appendicitis
timeFrame: one year
measure: Age distribution in patients with suspected appendicitis
timeFrame: one year
measure: prevalence of clinical findings in patients with suspected appendicitis
timeFrame: one year
Other outcomes:
Locations:
city: Gorgan
country: Iran, Islamic Republic of
facility: Golestan University of Medical Sciences, faculty of medicine
state: Golestan
Study officials:
References:
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citation: Tavra A, Quien D, Barcot O. Oncological aspect of incidental appendectomy with regard to histopathological findings: A retrospective cohort study. Eur J Surg Oncol. 2023 Oct;49(10):107013. doi: 10.1016/j.ejso.2023.107013. Epub 2023 Aug 11.
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citation: Henriksen SR, Rosenberg J, Fonnes S. Other Pathologies Were Rarely Reported after Laparoscopic Surgery for Suspected Appendicitis: A Systematic Review and Meta-Analysis. Dig Surg. 2023;40(3-4):91-99. doi: 10.1159/000531283. Epub 2023 Jul 18.
citation: Jukic M, Nizeteo P, Matas J, Pogorelic Z. Trends and Predictors of Pediatric Negative Appendectomy Rates: A Single-Centre Retrospective Study. Children (Basel). 2023 May 15;10(5):887. doi: 10.3390/children10050887.
citation: Pineda Villeda RH, Flores Reyes DL, Suazo Rivera JF. Acute Appendicitis: Epidemiological, Clinical, Surgical, and Post-surgical Characteristics in a Honduran General Hospital. Cureus. 2023 Jun 14;15(6):e40428. doi: 10.7759/cureus.40428. eCollection 2023 Jun.