Clinical trial NCT03899155: Pan Tumor Rollover Study
Official title: Pan-Tumor Study for Long-term Treatment of Cancer Patients Who Have Participated in BMS Sponsored Trials Investigating Nivolumab and Other Cancer Therapies
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE2
Conditions: Cancer
Keywords: Rollover
pan-tumor
Lead sponsor: Bristol-Myers Squibb
Sponsor class: INDUSTRY
Collaborators: name: Exelixis
name: Novartis
name: Clovis Oncology, Inc.
name: Janssen Pharmaceuticals
First posted: 2019-04-02
Enrollment: 1500
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Main Objective of this study is to examine long-term safety of nivolumab monotherapy including combinations and other cancer therapies in various tumor types.


Eligibility criteria: Inclusion Criteria:

* Signed Written Informed Consent.
* Eligible to receive continued study treatment per the Parent Study, including treatment beyond progression per investigator assessment in the Parent Study.
* On treatment hold in the Parent Study following long-lasting response or are eligible for treatment rechallenge as defined in the Parent Study.
* WOCBP and male participants who are sexually active must agree to follow instructions for method(s) of contraception as described below and included in the ICF.

Exclusion Criteria:

* Participant is not eligible for study treatment per the Parent Study eligibility criteria.
* Participants not receiving clinical benefit as assessed by the Investigator.
* Any clinical adverse event (AE), laboratory abnormality, or intercurrent illness which, in the opinion of the Investigator, indicates that participation in the study is not in the best interest of the participant.
* Other protocol-defined Inclusion/Exclusion Criteria apply

Primary outcomes:
measure: Incidence of Adverse Events (AEs)
timeFrame: From Day 1 up to 135 Days after discontinuation of treatment
measure: Incidence of drug related AEs
timeFrame: From Day 1 up to 135 Days after discontinuation of treatment
measure: Incidence of AEs leading to Discontinuation
timeFrame: From Day 1 up to 135 Days after discontinuation of treatment
measure: Incidence of Serious Adverse Events (SAEs)
timeFrame: From signature of Informed Consent up to 135 Days after discontinuation of treatment
measure: Incidence of Select AEs
timeFrame: From Day 1 up to 135 Days after discontinuation of treatment
measure: Incidence of Immune-Mediated AEs
timeFrame: From Day 1 up to 135 Days after discontinuation of treatment
measure: Incidence of Death
timeFrame: From signature of Informed Consent up to 135 Days after discontinuation of treatment
Secondary outcomes:
Other outcomes:
Locations:
city: Huntsville
country: United States
facility: Aichi Cancer Center Hospital
state: Alabama
city: Tucson
country: United States
facility: University of Arizona College of Medicine
state: Arizona
city: Lynwood
country: United States
facility: Innovative Clinical Research Institute
state: California
city: San Francisco
country: United States
facility: Local Institution
state: California
city: San Francisco
country: United States
facility: UCSF Medical Center - Helen Diller Family Comprehensive Cancer Center - Melanoma Center
state: California
city: Aurora
country: United States
facility: University of Colorado
state: Colorado
city: New Haven
country: United States
facility: Local Institution - 0095
state: Connecticut
city: Washington
country: United States
facility: Georgetown-Lombardi Comprehensive Cancer Center
state: District of Columbia
city: Ocala
country: United States
facility: Florida Cancer Affiliates
state: Florida
city: Orlando
country: United States
facility: Local Institution
state: Florida
city: Tampa
country: United States
facility: H. Lee Moffitt Cancer Center and Research Institute Hospital; Inc.
state: Florida
city: Chicago
country: United States
facility: Local Institution - 0105
state: Illinois
city: Maywood
country: United States
facility: Local Institution
state: Illinois
city: Park Ridge
country: United States
facility: Advocate Medical Group - Park Ridge - Luther Ln - Oncology
state: Illinois
city: Westwood
country: United States
facility: University of Kansas Cancer Center
state: Kansas
city: Wichita
country: United States
facility: Cancer Center of Kansas
state: Kansas
city: Louisville
country: United States
facility: University of Louisville-James Graham Brown Cancer Center
state: Kentucky
city: Baltimore
country: United States
facility: Johns Hopkins
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
city: Boston
country: United States
facility: Dana_Farber Cancer Institute (DFCI)
state: Massachusetts
city: Boston
country: United States
facility: Local Institution - 0081
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan Rogel Comprehensive Cancer Center UMCCC
state: Michigan
city: Minneapolis
country: United States
facility: Allina Health
state: Minnesota
city: Saint Louis
country: United States
facility: Local Institution
state: Missouri
city: Omaha
country: United States
facility: Local Institution - 0205
state: Nebraska
city: Lebanon
country: United States
facility: Dartmouth-Hitchcock Medical Center
state: New Hampshire
city: Albuquerque
country: United States
facility: Local Institution
state: New Mexico
city: Buffalo
country: United States
facility: Roswell Park Cancer Institute
state: New York
city: Mineola
country: United States
facility: Local Institution - 0413
state: New York
city: New York
country: United States
facility: Local Institution
state: New York
city: New York
country: United States
facility: Local Institution - 0202
state: New York
city: New York
country: United States
facility: Local Institution
state: New York
city: New York
country: United States
facility: Weill Cornell Medical College
state: New York
city: Charlotte
country: United States
facility: Levine Cancer Center
state: North Carolina
city: Durham
country: United States
facility: Duke University
state: North Carolina
city: Cincinnati
country: United States
facility: Oncology Hematology Care
state: Ohio
city: Cincinnati
country: United States
facility: Local Institution - 0408
state: Ohio
city: Cleveland
country: United States
facility: Local Institution
state: Ohio
city: Columbus
country: United States
facility: The Ohio University
state: Ohio
city: Tulsa
country: United States
facility: Local Institution - 0246
state: Oklahoma
city: Allentown
country: United States
facility: Lehigh Valley Hospital
state: Pennsylvania
city: Easton
country: United States
facility: St. Lukes University Health Network
state: Pennsylvania
city: Lancaster
country: United States
facility: Local Institution - 0400
state: Pennsylvania
city: Natrona Heights
country: United States
facility: Allegheny Valley Hospital
state: Pennsylvania
city: Philadelphia
country: United States
facility: Local Institution
state: Pennsylvania
city: Philadelphia
country: United States
facility: Local Institution - 0162
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Local Institution - 0110
state: Pennsylvania
city: Charleston
country: United States
facility: Charleston Oncology
state: South Carolina
city: Greenville
country: United States
facility: Local Institution
state: South Carolina
city: Chattanooga
country: United States
facility: Local Institution
state: Tennessee
city: Nashville
country: United States
facility: Tennesse Oncology
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt University Medical Center
state: Tennessee
city: Dallas
country: United States
facility: Local Institution
state: Texas
city: Houston
country: United States
facility: Local Institution - 0364
state: Texas
city: Salt Lake City
country: United States
facility: Huntsman Cancer Institute
state: Utah
city: Charlottesville
country: United States
facility: Local Institution
state: Virginia
city: Renton
country: United States
facility: Public Hospital of King County District 1 Valley Medical Center
state: Washington
city: Madison
country: United States
facility: Local Institution - 0124
state: Wisconsin
city: Madison
country: United States
facility: UW Health - UW Carbone Cancer Center - Medical Oncology Clinic
state: Wisconsin
city: Berazategui
country: Argentina
facility: Centro Oncologico y de Investigacion Buenos Aires
state: Buenos Aires
city: Viedma
country: Argentina
facility: Local Institution - 0405
state: Rio Negro
city: Rosario
country: Argentina
facility: Local Institution - 0407
state: Santa Fe
city: San Miguel De Tucumán
country: Argentina
facility: Local Institution - 0191
state: Tucuman
city: San Miguel De Tucumán
country: Argentina
facility: CAIPO Centro para la Atencion Integral del Paciente Oncologico
state: Tucumán
city: Buenos Aires
country: Argentina
facility: Local Institution - 0201
city: Buenos Aires
country: Argentina
facility: Instituto Fleming
city: Caba
country: Argentina
facility: Local Institution
city: Cordoba
country: Argentina
facility: Fundacion Richardet Longo - IONC
city: Cordoba
country: Argentina
facility: Local Institution - 0170
city: Coffs Harbour
country: Australia
facility: North Coast Area Health Service NCAHS - The North Coast Cancer Institute NCCI - Coffs Harbour Health Campus
state: New South Wales
city: North Sydney
country: Australia
facility: Melanoma Institute Australia
state: New South Wales
city: Sydney
country: Australia
facility: Chris OBrien Lifehouse Hospital
state: New South Wales
city: Waratah
country: Australia
facility: Calvary Mater Newcastle
state: New South Wales
city: Westmead
country: Australia
facility: Westmead Hospital
state: New South Wales
city: Greenslopes
country: Australia
facility: Gallipoli Medical Foundation
state: Queensland
city: Greenslopes
country: Australia
facility: Local Institution - 0372
state: Queensland
city: South Brisbane
country: Australia
facility: Local Institution
state: Queensland
city: Southport
country: Australia
facility: Tasman Oncology Research Ltd
state: Queensland
city: Adelaide
country: Australia
facility: Local Institution
state: South Australia
city: Elizabeth Vale
country: Australia
facility: Lyell McEwin Hospital
state: South Australia
city: Ballarat
country: Australia
facility: Local Institution - 0411
state: Victoria
city: Fitzroy
country: Australia
facility: St Vincents Hospital Melbourne
state: Victoria
city: Malvern
country: Australia
facility: Cabrini Hospital Malvern
state: Victoria
city: Murdoch
country: Australia
facility: Local Institution - 0174
state: Western Australia
city: Graz
country: Austria
facility: Local Institution - 0254
state: Steiermark
city: Linz
country: Austria
facility: Ordensklinikum Linz GmbH Elisabethinen
state: Upper Austria
city: Vienna
country: Austria
facility: Local Institution - 0104
city: Wels
country: Austria
facility: Local Institution - 0145
city: Wien
country: Austria
facility: Allgemeines Krankenhaus Wien
city: Brussel
country: Belgium
facility: Local Institution - 0329
city: Gent
country: Belgium
facility: Local Institution - 0232
city: Jette
country: Belgium
facility: Local Institution - 0139
city: Liege
country: Belgium
facility: Local Institution - 0261
city: Sint-Niklaas
country: Belgium
facility: Local Institution - 0293
city: Yvoir
country: Belgium
facility: Cliniques Universitaires UCL de Mont-Godinne (CHU)
city: Belo Horizonte
country: Brazil
facility: PERSONAL Oncologia de Precisao e Personalizada
state: Minas Gerais
city: Ijui
country: Brazil
facility: ONCOSITE - Centro de Pesquisa Clinica em Oncologia
state: RIO Grande DO SUL
city: Porto Alegre
country: Brazil
facility: Local Institution - 0093
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Irmandade da Santa Casa de Misericordia de Porto Alegre
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Hospital Sao Lucas Da Pucrs
state: Rio Grande Do Sul
city: Passo Fundo
country: Brazil
facility: Local Institution - 0379
state: RS
city: Porto Alegre
country: Brazil
facility: Local Institution - 0399
state: RS
city: Barretos
country: Brazil
facility: Hospital de Cancer de Barretos
state: Sao Paulo
city: Sao Jose do Rio Preto
country: Brazil
facility: Hospital de Base de Sao Jose do Rio Preto
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Local Institution - 0263
state: SAO Paulo
city: Sao Paulo
country: Brazil
facility: ICESP - Instituto do Cancer do Estado de Soo Paulo
state: SP
city: Sao Paulo
country: Brazil
facility: Hospital Alemao Oswaldo Cruz
state: SP
city: Rio De Janeiro
country: Brazil
facility: National Cancer Institute (INCA)
city: Rio De Janeiro
country: Brazil
facility: Instituto de Educao Pesquisa e Gesto em Sade Instituto COI
city: Sao Paulo
country: Brazil
facility: Local Institution - 0340
city: Edmonton
country: Canada
facility: Cross Cancer Institute
state: Alberta
city: Vancouver
country: Canada
facility: Local Institution
state: British Columbia
city: Halifax
country: Canada
facility: Local Institution
state: Nova Scotia
city: Oshawa
country: Canada
facility: Durham Regional Cancer Ctr
state: Ontario
city: Toronto
country: Canada
facility: Princess Margaret Cancer Centre
state: Ontario
city: Montreal
country: Canada
facility: Local Institution - 0040
state: Quebec
city: Montreal
country: Canada
facility: Local Institution - 0308
state: Quebec
city: Temuco
country: Chile
facility: Local Institution - 0363
state: Araucania
city: Providencia
country: Chile
facility: Local Institution - 0398
state: Metropolitana
city: Santiago de Chile
country: Chile
facility: Bradford Hill Centro de Investigacion Clinica
state: Metropolitana
city: Santiago
country: Chile
facility: Fundacion Arturo Lopez Perez
state: Metropolitana
city: Santiago
country: Chile
facility: Local Institution
state: Metropolitana
city: Vina Del Mar
country: Chile
facility: Local Institution - 0079
city: Hefei
country: China
facility: Local Institution - 0169
state: Anhui
city: Beijing
country: China
facility: Local Institution - 0198
state: Beijing
city: Guangzhou
country: China
facility: Local Institution
state: Guangdong
city: Guangzhou
country: China
facility: Local Institution - 0383
state: Guangdong
city: Harbin Shi
country: China
facility: Harbin Medical University Cancer Hospital
state: Heilongjiang
city: Harbin
country: China
facility: Local Institution - 0245
state: Heilongjiang
city: Harbin
country: China
facility: Harbin Medical University - Cancer Hospital
state: Heilongjiang
city: Changsha
country: China
facility: Local Institution - 0172
state: Hunan
city: Changsha
country: China
facility: Xiangya Hospital Central South University
state: Hunan
city: Changsha
country: China
facility: Hunan Cancer Hospital
state: Hunan
city: Nanjing
country: China
facility: Local Institution - 0348
state: Jiangsu
city: Changchun
country: China
facility: Jilin University (JLU) - First Affiliated Hospital - Cancer Center
state: Jilin
city: Changchun
country: China
facility: Jilin Cancer Hospital
state: Jilin
city: Xian
country: China
facility: Tangdu Hospital of Fourth Military Medical University
state: Shaanxi
city: Xian
country: China
facility: Local Institution - 0395
state: Shan3XI
city: Shanghai
country: China
facility: Ruijin Hospital Shanghai Jiaotong University School of Medicine
state: Shanghai
city: Shanghai
country: China
facility: Fudan University - Shanghai Cancer Center FUSCC
state: Shanghai
city: Shanghai
country: China
facility: Local Institution - 0278
state: Shanghai
city: Shanghai
country: China
facility: Local Institution - 0325
state: Shanghai
city: Shanghai
country: China
facility: Local Institution - 0188
state: Shanghai
city: Hangzhou
country: China
facility: Sir Run Run Shaw Hospital
state: Zhejiang
city: Hangzhou
country: China
facility: The First Affiliated Hospital Zhejiang University (The First Hospital of Zhejiang Province)
city: Nanjing
country: China
facility: Local Institution - 0390
city: Prague
country: Czechia
facility: Univerzita Karlova v Praze a Vseobecna fakultni nemocnice v Praze
state: NY
city: Brno
country: Czechia
facility: Local Institution - 0371
city: Hradec Kralove
country: Czechia
facility: FNHK Klinika onkologie a radioterapie
city: Olomouc
country: Czechia
facility: Local Institution - 0150
city: Odense C
country: Denmark
facility: Local Institution
city: Helsinki
country: Finland
facility: Local Institution
city: Bordeaux
country: France
facility: Local Institution - 0006
state: Gironde
city: Paris
country: France
facility: Local Institution - 0387
state: Ile De France
city: Vandoeuvre-Les-Nancy
country: France
facility: CHU De Nancy Hopital De Brabois
state: Meurthe-Et-Moselle
city: Clermont-Ferrand
country: France
facility: Centre Jean Perrin
city: Creteil
country: France
facility: Centre Hospitalier Intercommunal de Creteil CHIC
city: Dijon Cedex
country: France
facility: CHU Dijon
city: Dijon
country: France
facility: Centre Georges-Francois Leclerc
city: La Tronche
country: France
facility: CHU Grenobles Alpes
city: Lille Cedex
country: France
facility: Pole Biologie Pathologie Genetique - CHU de Lille
city: Marseille Cedex 20
country: France
facility: APHM - Hopital Nord
city: Marseille
country: France
facility: APHM - Hopital de la Timone
city: Montpellier
country: France
facility: CHU Montpellier
city: Montpellier
country: France
facility: Local Institution
city: Nantes Cedex 1
country: France
facility: CHU Nantes - Hotel Dieu
city: Nantes
country: France
facility: Local Institution - 0300
city: Paris Cedex 15
country: France
facility: Hopital europeen Georges Pompidou HEGP
city: Paris
country: France
facility: Hospital Saint-Louis
city: Paris
country: France
facility: Local Institution - 0301
city: Pierre-Benite Cedex
country: France
facility: Centre Hospitalier Lyon Sud
city: Rennes
country: France
facility: Local Institution
city: Saint-Priest en Jarez
country: France
facility: Local Institution - 0401
city: Suresnes
country: France
facility: Local Institution - 0392
city: Toulon
country: France
facility: Hopital Musse
city: Toulouse Cedex
country: France
facility: Local Institution
city: Villejuif Cedex
country: France
facility: Institut Gustave Roussy
city: Loewenstein
country: Germany
facility: Local Institution - 0386
state: Baden Wuerttemberg
city: Muenchen
country: Germany
facility: LMU Muenchen
state: Bayern
city: Nuremberg
country: Germany
facility: Local Institution - 0332
state: Bayern
city: Essen
country: Germany
facility: Local Institution - 0250
state: Nordrhein-Westfalen
city: Essen
country: Germany
facility: Local Institution - 0375
state: Nordrhein-westfalen
city: Essen
country: Germany
facility: Local Institution - 0402
state: NRW
city: Aachen
country: Germany
facility: Universitaetsklinikum Aachen
city: Berlin
country: Germany
facility: Charite Universitaetsmedizin Berlin
city: Buxtehude
country: Germany
facility: Elbe Klinikum Buxtehude
city: Cologne
country: Germany
facility: Local Institution - 0296
city: Freiburg
country: Germany
facility: University of Freiburg
city: Gera
country: Germany
facility: Local Institution
city: Gera
country: Germany
facility: SRH Wald-Klinikum Gera GmbH
city: Goettingen
country: Germany
facility: Local Institution
city: Gottingen
country: Germany
facility: Universitatsmedizin Gottingen
city: Hamburg
country: Germany
facility: UKE Neurochirurgische Klinik
city: Heidelberg
country: Germany
facility: Local Institution
city: Heidelberg
country: Germany
facility: Thoraxklinik
city: Heidelberg
country: Germany
facility: Oberaeztin Neurologische Klinik und Nationales Tumorzentrum Universitaetsklinik Heidelberg Im Neuenheimer
city: Heilbronn
country: Germany
facility: SLK-Kliniken Heilbronn GmbH
city: Jena
country: Germany
facility: Universitaetsklinikum Jena - Klinik und Poliklinik fuer Urologie
city: Kassel
country: Germany
facility: Klinikum Kassel - Klinik fuer Haematologie; Onkologie und Immunologie
city: Kiel
country: Germany
facility: Local Institution
city: Kiel
country: Germany
facility: Unv Schleswig-Holstein Campus Kiel
city: Koeln
country: Germany
facility: Local Institution
city: Loewenstein
country: Germany
facility: Local Institution - 0298
city: Luebeck
country: Germany
facility: Local Institution - 0098
city: Mainz
country: Germany
facility: Local Institution - 0089
city: Mainz
country: Germany
facility: Local Institution
city: Tubingen
country: Germany
facility: Local Institution - 0017
city: Tuebingen
country: Germany
facility: Local Institution - 0277
city: Heraklion
country: Greece
facility: Local Institution - 0244
state: Crete
city: Athens
country: Greece
facility: General Hospital of Athens Laiko
city: Athens
country: Greece
facility: Sotiria General Hospital of Chest Diseases
city: Athens
country: Greece
facility: Local Institution - 0171
city: Athens
country: Greece
facility: Local Institution - 0381
city: Athens
country: Greece
facility: Local Institution - 0295
city: Athens
country: Greece
facility: Metropolitan Hospital
city: Patras
country: Greece
facility: Local Institution
city: Thessaloniki
country: Greece
facility: Interbalcan Medical Centre
city: Hong Kong
country: Hong Kong
facility: Queen Mary Hospital
city: Gyongyossolymos
country: Hungary
facility: Matrai Gyogyintezet
state: Heves
city: Budapest
country: Hungary
facility: Local Institution - 0226
city: Budapest
country: Hungary
facility: Orszagos Koranyi TBC es Pulmonologiai Intezet
city: Debrecen
country: Hungary
facility: DE Klinikai Kozpont
city: Dublin
country: Ireland
facility: Local Institution - 0227
city: Limerick
country: Ireland
facility: Local Institution
city: Haifa
country: Israel
facility: Rambam Health Care Campus
city: Jerusalem
country: Israel
facility: Hadassah Medical Organization
city: Petach Tikva
country: Israel
facility: Local Institution
city: Ramat Gan
country: Israel
facility: Sheba Medical Center
city: Tiqwa
country: Israel
facility: Local Institution - 0350
city: Meldola
country: Italy
facility: IRCCS - Istituto Scientifico Romagnolo per lo Studio dei Tumori - Dino Amadori - Srl
state: Fc
city: Rozzano
country: Italy
facility: Local Institution - 0333
state: MI
city: Roma
country: Italy
facility: Istituto Nazionale dei Tumori Regina Elena
state: RM
city: Bari
country: Italy
facility: Local Institution - 0034
city: Bergamo
country: Italy
facility: ASST Papa Giovanni XXIII
city: Candiolo
country: Italy
facility: Local Institution - 0326
city: Catania
country: Italy
facility: Local Institution - 0359
city: Genova
country: Italy
facility: Local Institution - 0251
city: Genova
country: Italy
facility: Local Institution
city: Meldola
country: Italy
facility: Local Institution - 0108
city: Meldola
country: Italy
facility: Local Institution - 0303
city: Milano
country: Italy
facility: Local Institution
city: Milano
country: Italy
facility: IRCCS Istituto Europeo di Oncologia
city: Milano
country: Italy
facility: IRCCS Istituto Europeo di Oncologia
city: Milano
country: Italy
facility: Local Institution
city: Milan
country: Italy
facility: Fondazione IRCCS istituto Neurologico Carlo Besta;
city: Milan
country: Italy
facility: Local Institution - 0096
city: Milan
country: Italy
facility: Local Institution - 0351
city: Modena
country: Italy
facility: Local Institution - 0327
city: Napoli
country: Italy
facility: Istituto Nazionale dei Tumori
city: Napoli
country: Italy
facility: Istituto Nazionale Tumori - Fondazione Pascale Italy
city: Napoli
country: Italy
facility: Local Institution - 0292
city: Padova
country: Italy
facility: Istituto Oncologico Veneto
city: Ravenna
country: Italy
facility: AUSL Romagna
city: Siena
country: Italy
facility: Local Institution - 0003
city: Terni
country: Italy
facility: Local Institution - 0291
city: Torino
country: Italy
facility: Azienda Ospedaliera Citta della Salute e della Scienza
city: Hirosaki-shi
country: Japan
facility: Hirosaki University Hospital
state: Aomori
city: Chiba-shi
country: Japan
facility: Local Institution - 0409
state: Chiba
city: Kashiwa-Shi
country: Japan
facility: National Cancer Center Hospital East
state: Chiba
city: Matsuyama-shi
country: Japan
facility: Local Institution - 0394
state: Ehime
city: Matsuyama-shi
country: Japan
facility: Local Institution - 0397
state: Ehime
city: Higashi-Ku, Fukuoka-shi
country: Japan
facility: Local Institution - 0393
state: Fukuoka
city: Kobe shi
country: Japan
facility: Kobe City Medical Center General Hospital
state: Hyogo
city: Tsukuba
country: Japan
facility: University of Tsukuba Hospital
state: Ibaraki
city: Kanazawa-shi
country: Japan
facility: Local Institution - 0219
state: Ishikawa
city: Yokohama
country: Japan
facility: Yokohama City University Medical Center
state: Kanagawa
city: Natori
country: Japan
facility: Miyagi Cancer Center
state: Miyagi
city: Niigata-City
country: Japan
facility: Local Institution - 0230
state: Niigata
city: Osakasayama
country: Japan
facility: Kindai University Hospital
state: Osaka
city: Takatsuki
country: Japan
facility: Local Institution - 0212
state: Osaka
city: Chuo-Ku, Hamamatsu-Shi
country: Japan
facility: Local Institution - 0391
state: Shizuoka
city: Adachi-Ku
country: Japan
facility: Local Institution - 0406
state: Tokyo
city: Bunkyo-Ku
country: Japan
facility: Local Institution - 0404
state: Tokyo
city: Chuo-ku
country: Japan
facility: National Cancer Center Hospital
state: Tokyo
city: Koto-Ku
country: Japan
facility: The Cancer Institute Hospital of JFCR
state: Tokyo
city: Shinjuku
country: Japan
facility: Keio University Hospital
state: Tokyo
city: Fukuoka
country: Japan
facility: Local Institution - 0224
city: Hiroshima
country: Japan
facility: Hiroshima University Hospital
city: Niigata
country: Japan
facility: Niigata University Medical and Dental Hospital
city: Seongnam
country: Korea, Republic of
facility: Local Institution - 0389
state: Gyeonggi-do
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center
state: Songpa-gu
city: Gyeonggi-do
country: Korea, Republic of
facility: National Cancer Center
city: Seongnam-si
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
city: Seoul
country: Korea, Republic of
facility: Local Institution - 0206
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
city: Suwon Si
country: Korea, Republic of
facility: Local Institution - 0207
city: Mexico City
country: Mexico
facility: Local Institution - 0410
state: Cdmx
city: Tlalpan
country: Mexico
facility: Local Institution - 0181
state: Ciudad De Mexico
city: Leon
country: Mexico
facility: Local Institution - 0152
state: Guanajuato
city: Zapopan
country: Mexico
facility: Local Institution - 0338
state: Jalisco
city: Morelia
country: Mexico
facility: Hospital Victoria Medical Center
state: Michoacan
city: Monterrey
country: Mexico
facility: Local Institution - 0286
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Local Institution - 0354
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Local Institution - 0396
state: Nuevo LEON
city: Oaxaca de Juarez
country: Mexico
facility: Centro de Investigacion Clinica de Oaxaca
state: Oaxaca
city: Santiago de Queretaro
country: Mexico
facility: Local Institution - 0343
state: Queretaro
city: Ciudad de Mexico
country: Mexico
facility: Local Institution - 0344
city: Ciudad de Mexico
country: Mexico
facility: Local Institution - 0346
city: Ciudad de Mexico
country: Mexico
facility: Local Institution - 0337
city: San Luis Potosi
country: Mexico
facility: Local Institution - 0367
city: Amsterdam
country: Netherlands
facility: Local Institution - 0335
state: Noord-Holland
city: Rotterdam
country: Netherlands
facility: Local Institution
city: Auckland
country: New Zealand
facility: Auckland City Hospital-Liver Research Unit
city: Christchurch
country: New Zealand
facility: Local Institution - 0271
city: Dunedin
country: New Zealand
facility: Southern District Hospital (SDHB) - Dunedin Hospital
city: Tauranga
country: New Zealand
facility: Tauranga Hospital
city: Bergen
country: Norway
facility: Haukeland Universitetssjukehus
city: Oslo
country: Norway
facility: Oslo University Hospital
city: Santiago de Surco
country: Peru
facility: Local Institution - 0179
state: Lima
city: Lima
country: Peru
facility: Local Institution - 0385
city: Bydgoszcz
country: Poland
facility: Local Institution - 0358
state: Kujawsko-pomorskie
city: Biala Podlaska
country: Poland
facility: Local Institution - 0336
state: Lubelskie
city: Olsztyn
country: Poland
facility: Local Institution - 0414
state: Warminsko-Mazurskie
city: Gdansk
country: Poland
facility: Uniwersyteckie Centrum KliniczneUniwersyteckie Centrum Kliniczne; II Klinika Kardiologii i Elektroterapii Serca
city: Gdansk
country: Poland
facility: Wojewodzkie Centrum Onkologii
city: Krakow
country: Poland
facility: Local Institution - 0377
city: Krakow
country: Poland
facility: Narodowy Instytut Onkologii Oddzial w Krakowie
city: Krakow
country: Poland
facility: Local Institution - 0373
city: Lodz
country: Poland
facility: Instytut MSF Sp zoo
city: Lublin
country: Poland
facility: Ms Pneumed Janusz Milanowski Katarzyna Szmygin-Milanowska Sp. J.
city: Poznan
country: Poland
facility: Centrum Medyczne Pratia Poznan
city: Warsaw
country: Poland
facility: Wojskowy Instytut Medyczny
city: Warsaw
country: Poland
facility: Local Institution
city: Warszawa
country: Poland
facility: Local Institution - 0328
city: Warszawa
country: Poland
facility: Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology
city: Lisboa
country: Portugal
facility: Centro Hospitalar de Lisboa Norte EPE - HPV
city: Lisbon
country: Portugal
facility: Instituto Portugues de Oncologio de Lisboa
city: Porto
country: Portugal
facility: Local Institution - 0142
city: San Juan
country: Puerto Rico
facility: FDI Clinical Research
city: Craiova
country: Romania
facility: Local Institution - 0378
state: Dolj
city: Bucharest
country: Romania
facility: Centrul Medical Focus
state: Sector 2
city: Bucharest
country: Romania
facility: Institutul Oncologic Bucuresti IOB
city: Cluj Napoca
country: Romania
facility: Medisprof SRL
city: Cluj Napoca
country: Romania
facility: Institutul Oncologic Prof. Dr. I. Chiricuta
city: Cluj-Napoca
country: Romania
facility: Local Institution - 0189
city: Craiova
country: Romania
facility: Centrul de Oncologie Sf Nectarie
city: Oradea
country: Romania
facility: Local Institution - 0133
city: Suceava
country: Romania
facility: Sc Sigmedical Srl
city: Krasnodar
country: Russian Federation
facility: Local Institution - 0257
state: Krasnodar Region
city: Krasnoyarsk
country: Russian Federation
facility: Local Institution - 0256
city: Moscow
country: Russian Federation
facility: N.N. Blokhin National Medical Research Center of Oncology
city: Moscow
country: Russian Federation
facility: VitaMed LLC
city: San Sebastian
country: Spain
facility: Onkologikoa Of San Sebastian
state: Guipuzcoa
city: Majadahonda
country: Spain
facility: Hospital Universitario Puerta de Hierro de Majadahonda
state: Madrid
city: Pamplona
country: Spain
facility: Clinica Universidad de Navarra
state: Navarra
city: A Coruna
country: Spain
facility: Hospital Teresa Herrera C.H.U.A.C.
city: A Coruna
country: Spain
facility: Local Institution - 0382
city: Alicante
country: Spain
facility: Local Institution - 0173
city: Badalona
country: Spain
facility: Catalan Institute of Badalona Hospital Germans Trias i Pujol ICO
city: Barcelona
country: Spain
facility: Local Institution - 0384
city: Barcelona
country: Spain
facility: Hospital Universitari Vall d Hebron
city: Barcelona
country: Spain
facility: Hospital Clinic de Barcelona
city: Barcelona
country: Spain
facility: Hospital Clinic de Barcelona
city: Barcelona
country: Spain
facility: Institut Catala dOncologia LHospitalet
city: Barcelona
country: Spain
facility: Local Institution
city: Burgos
country: Spain
facility: Local Institution - 0146
city: Granada
country: Spain
facility: Local Institution - 0144
city: Madrid
country: Spain
facility: Local Institution - 0273
city: Madrid
country: Spain
facility: Local Institution - 0357
city: Madrid
country: Spain
facility: Clinica Universidad de Navarra Madrid
city: Madrid
country: Spain
facility: Centro Oncologico MD ANDERSON Internacional Espana
city: Madrid
country: Spain
facility: Local Institution
city: Madrid
country: Spain
facility: Hospital Ramon y Cajal
city: Madrid
country: Spain
facility: Hospital Universitario Fundacion Jimenez Diaz
city: Madrid
country: Spain
facility: Hospital Universitario 12 de Octubre
city: Madrid
country: Spain
facility: Local Institution - 0380
city: Madrid
country: Spain
facility: Local Institution
city: Madrid
country: Spain
facility: Hospital Universitario HM Sanchinarro
city: Malaga
country: Spain
facility: Hospital Regional Universitario Carlos Haya
city: Santa Cruz de Tenerife
country: Spain
facility: Local Institution
city: Santander
country: Spain
facility: Local Institution - 0352
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Macarena
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen del Roco
city: Valencia
country: Spain
facility: Hospital General Universitario de Valencia
city: Valencia
country: Spain
facility: Hospital Universitario y Politecnico de La Fe
city: Goteborg
country: Sweden
facility: Local Institution
city: Malmoe
country: Sweden
facility: Local Institution - 0036
city: Umea
country: Sweden
facility: Local Institution
city: Basel
country: Switzerland
facility: Local Institution - 0119
city: St.Gallen
country: Switzerland
facility: Local Institution - 0403
city: Zurich
country: Switzerland
facility: UniversitaetsSpital Zuerich - Dermatology
city: Taichung
country: Taiwan
facility: Local Institution - 0388
city: Tainan
country: Taiwan
facility: National Cheng Kung University Hospital
city: Taipei
country: Taiwan
facility: Local Institution - 0412
city: Taipei
country: Taiwan
facility: Taipei Veterans General Hospital TPVGH
city: Ankara
country: Turkey
facility: Local Institution - 0330
city: London
country: United Kingdom
facility: North Middlesex University Hospital
state: Greater London
city: London
country: United Kingdom
facility: University College Hospital
state: Greater London
city: London
country: United Kingdom
facility: Royal Marsden Hospital Sutton
state: Greater London
city: London
country: United Kingdom
facility: Royal Marsden Hospital
state: Greater London
city: Manchester
country: United Kingdom
facility: The Christie Hospital
state: Greater Manchester
city: Southampton
country: United Kingdom
facility: Local Institution - 0195
state: Hampshire
city: Maidstone
country: United Kingdom
facility: Local Institution - 0231
state: Kent
city: Northwood
country: United Kingdom
facility: East & North Hertfordshire NHS Trust
state: Middlesex
city: Edinburgh
country: United Kingdom
facility: Local Institution - 0299
state: Scotland
Study officials:
affiliation: Bristol-Myers Squibb
name: Bristol-Myers Squibb
role: STUDY_DIRECTOR
References: