Clinical trial NCT05219682: Changes in Brain Activity During Mirror Therapy and Virtual Reality Therapy
Official title: Changes in Brain Activity in Tactile Stimulus Therapy and Ruka Ruk Therapy Compared to Mirror Therapy in Upper Limb Rehabilitation.
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Healthy
Age of Probands 18 - 55 Years
Keywords: EEG
Virtual Reality
Rehabilitation
Mirror neurons
Mirror Therapy
Lead sponsor: Charles University, Czech Republic
Sponsor class: OTHER
First posted: 2022-02-02
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Each participant started with EEG measurements at rest followed by 3 EEG measurements in mirror therapy and 3 EEG measurements with mirror therapy in virtual reality. The order of measurement was randomized.
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this study is to compare electroencephalographic activity in upper limb rehabilitation with mirror therapy and virtual reality rehabilitation.

Detailed description: This is an experiment measuring EEG to healthy adult probands during mirror therapy and VR mirroring therapy in the upper limb. The experiment will be supplemented by haptic contact and stimulation of the upper limb with a foam roller. According to the instructions, the participants will perform a predetermined movement with one upper limb - clenching the fist. In one part with the mirror, in the other part the sensor for sensing the movement of the hand detects the movement, the software creates the illusion that the patient performs the same movement with the dominant and non-dominant upper limb. The patient sees on the screen the illusion of movement of both of his upper limbs. During therapy, the other upper limb will be tactively stimulated haptically and with a foam roller. Data collection will take place by measuring the electrical activity of the brain using an EEG device. The obtained data will then be processed and evaluated with the help of the sLORETA program. The aim of this work is to compare the brain activity from the above therapies with the resting state of the proband and to focus on the activity of mirror neurons.

Eligibility criteria: Inclusion Criteria:

* a healthy individual with a valid medical examination.

Exclusion Criteria:

* Having a stroke or other illness that is related to a disorder of movement of the upper limbs. Severe visual or auditory deficit and decompensated epilepsy due to screen movement tracking. Persons with acute (especially infectious) diseases did not participate in the research.

Primary outcomes:
measure: Comparison of EEG for each intervention versus the resting phase of the measurement
timeFrame: month
Secondary outcomes:
measure: Comparison of electroencephalographic recordings from mirror therapy with therapy in virtual reality
timeFrame: month
Other outcomes:
Locations:
city: Prague
country: Czechia
facility: Faculty of Physical Education and Sport at Charles University
Study officials:
affiliation: Employee
name: MUDr. David Pánek, Ph.D.
role: STUDY_DIRECTOR
References: