Clinical trial NCT02838927: Survey on Epidemiology of Hypoparathyroidism in France
Official title: Epi-Hypo: Survey on Epidemiology of Hypoparathyroidism in France
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Hypoparathyroidism
Keywords: Hypoparathyroidism
Epidemiology
Medication Therapy Management
Lead sponsor: European Georges Pompidou Hospital
Sponsor class: OTHER
Collaborators: name: Oscar - Filière Santé Maladies Rares
First posted: 2016-07-20
Enrollment: 3000
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All patients for whom hypoparathyroidism is diagnosed in France

Brief summary: Very few data has been published on the epidemiology of hypoparathyroidism worldwide: none exists specifically for France. Hypoparathyroidism could led to complications. Here, the investigators plan to collect data about both epidemiology, medication and complication of hypoparathyroidism in France.

Detailed description: Very few data has been published on the epidemiology of hypoparathyroidism worldwide. None exists specifically in France. Hypoparathyroidism could led to complications: e.g. symptomatic hypocalcemia, calcifications (brain, eye and other soft tissues), nephrolithiasis/nephrocalcinosis, renal insufficiency. Here,the investigators plan to collect data about both epidemiology, medication and complication of hypoparathyroidism in France.

Eligibility criteria: Inclusion Criteria:

* patient fro whom chronic hypoparathyroidism is diagnosed
* patient living in France

Exclusion Criteria:

* patient who does not want his data to be collected in this registry
* pseudo-hypoparathyroidism
* acute hypoparathyroidism

Primary outcomes:
measure: Assessment of the epidemiology of patients with hypoparathyroidism in France
timeFrame: Through study completion, about 2 years
Secondary outcomes:
measure: Assessment of the biology at inclusion will describe the evolution of the included population from diagnosis to now (inclusion)
timeFrame: At inclusion (under treatment): through study completion, about 2 years
measure: Assessment of the management at inclusion will describe treatment and complications at inclusion
timeFrame: At inclusion (under treatment): through study completion, about 2 years
measure: Assessment of the biology (calcemia, calciuria, parathormone, creatininemia, phosphatemia & magnesemia) at diagnosis and drug therapy at inclusion will describe population
timeFrame: Through study completion, about 2 years
Other outcomes:
measure: Assessment of the physician's management will help describing the habits of french physician who manage hypoparathyroidism in terms of follow-up
timeFrame: At inclusion
Locations:
city: Saint-Denis
country: France
facility: Felix Guyon Hospital
state: La Réunion
city: Aix-en-Provence
country: France
facility: Hôpital Privé de Provence
city: Amiens
country: France
facility: Amiens University Hospital
city: Auch
country: France
facility: Clinic Auch Area
city: Aurillac
country: France
facility: Henri Mondor Hospital
city: Besançon
country: France
facility: Jean Minjoz Hospital
city: Blanquefort
country: France
facility: Blanquefort
city: Bobigny
country: France
facility: Avicenne Hospital, AP-HP
city: Bondy
country: France
facility: Jean Verdier Hospital, AP-HP
city: Bordeaux
country: France
facility: University Hospital
city: Bourgoin-Jallieu
country: France
facility: Bourgoin Jallieu Hospital
city: Brest
country: France
facility: La Cavale Blanche Hospital
city: Caen
country: France
facility: Côte de Nacre Hospital
city: Créteil
country: France
facility: Henri Mondor Hospital, APHP
city: Dax
country: France
facility: Dax-Côte d'Argent Hospital
city: Dijon
country: France
facility: University Hospital
city: Grenoble
country: France
facility: Grenoble Alpes Hospital
city: La Roche-sur-Yon
country: France
facility: CHD Vendée
city: Le Kremlin-Bicêtre
country: France
facility: Kremlin-Bicêtre Hospital, APHP
city: Le Mans
country: France
facility: Le Mans Hospital
city: Libourne
country: France
facility: Libourne Hospital
city: Lille
country: France
facility: Claude Huriez Hospital
city: Lyon
country: France
facility: Edouard Herriot Hospital, HCL
city: Marseille
country: France
facility: La Conception Hospital, AP-HM
city: Metz
country: France
facility: Clinic Metz Area
city: Metz
country: France
facility: Mercy Hospital
city: Montpellier
country: France
facility: Arnaud de Villeneuve Hospital
city: Mérignac
country: France
facility: Clinic area
city: Nancy
country: France
facility: Brabois Hospital
city: Nantes
country: France
facility: University Hospital
city: Nice
country: France
facility: University Hospital
city: Niort
country: France
facility: Georges Renon Hospital
city: Nîmes
country: France
facility: Caremeau Hospital
city: Paris
country: France
facility: European Georges Pompidou Hospital, APHP
city: Paris
country: France
facility: Clinic Paris Area
city: Paris
country: France
facility: Cochin Hospital, APHP
city: Paris
country: France
facility: Lariboisière Hospital, APHP
city: Paris
country: France
facility: Necker Hospital, AP-HP
city: Paris
country: France
facility: Pitié-Salpêtrière Hospital, APHP
city: Paris
country: France
facility: Saint-Louis Hospital, AP-HP
city: Paris
country: France
facility: Tenon Hospital, APHP
city: Passy
country: France
facility: Passy Hospital
city: Poitiers
country: France
facility: Clinic Poitiers Area
city: Quimper
country: France
facility: Laennec Hospital
city: Reims
country: France
facility: Reims University Hospital
city: Rennes
country: France
facility: Clinic Rennes Area
city: Rouen
country: France
facility: Charles Nicolle Hospital
city: Saint Florent Le Vieil
country: France
facility: Saint Florent Le Vieil
city: Saint-Junien
country: France
facility: Clinic Area
city: Saint-Ouen
country: France
facility: Clinique du Landy
city: Strasbourg
country: France
facility: Hautepierre Hospital
city: Toulon
country: France
facility: Sainte Anne Hospital, HIA
city: Toulouse
country: France
facility: Larrey Hospital
city: Tourcoing
country: France
facility: Guy Chatiliez Hospital
city: Tours
country: France
facility: Bretonneau Hospital
city: Valenciennes
country: France
facility: Valenciennes Hospital
city: Villeneuve-Saint-Georges
country: France
facility: CHIV - Lucie et Raymond Aubrac
Study officials:
affiliation: European Georges Pompidou Hospital, APHP
name: Jean-Philippe Bertocchio, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bertocchio JP, Grosset N, Groussin L, Kamenicky P, Larceneux F, Lienhardt-Roussie A, Linglart A, Maruani G, Mirallie E, Pattou F, Seervai RNH, Sido C, Silve C, Vilfaillot A, Tabarin A, Vantyghem MC, Houillier P. Practice patterns for chronic hypoparathyroidism: data from patients and physicians in France. Endocr Connect. 2022 Jan 31;11(1):e210350. doi: 10.1530/EC-21-0350.