Clinical trial NCT01839227: Post-operative Cognitive Dysfunction and the Change of Regional Cerebral Oxygen Saturation in Elderly Patients Undergoing Spinal Surgery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Elderly Patients Undergoing Spinal Surgery
Keywords: Post-operative cognitive dysfunction
regional cerebral oxygen saturation
elderly
Lead sponsor: Yonsei University
Sponsor class: OTHER
First posted: 2013-04-24
Enrollment: 87
Sex: ALL
Minimum age (years): 65
Maximum age (years): 85
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SCREENING

Brief summary: Post operative cognitive dysfunction (POCD) is a well-recognized complication of patients undergoing cardiac surgery. Previous studies reported near-infrared spectroscopy provides information on the occurrence of cerebral desaturation resulted in POCD. But evidence of POCD after general surgery has been lacking. Especially, the prone position is used primarily for surgical access to the posterior spine, if there is any significant lowering of the legs or tilt of the entire table, venous returns may be decrease or augmented accordingly. The purpose of this study was to examine the relationship between POCD and intra-operative cerebral oxygen saturation after spine surgery in elderly patients.


Eligibility criteria: Inclusion Criteria:

* the patient undergoing the lumbar spine surgery in severance hospital

Exclusion Criteria:

* Patients who had previous cerebral disease, dementia, severe problems in hearing and understanding, or who were unable to provide informed consent were excluded.

Primary outcomes:
measure: K-MMSE
timeFrame: change of K-MMSE from baseine to 1 month
Secondary outcomes:
measure: visuomotor test(D-LOTCA battery)
timeFrame: measuring for visuomotor test during baseline and 1 month
measure: Regional cerebral oxymetry monitoring
timeFrame: measuring for Regional cerebral oxymetry monitoring during baseline and 1 month
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine
Study officials:
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