Clinical trial NCT06146595: Prevalence of Attention Deficit Hyperactivity Disorder and Its Comorbidities
Official title: Prevalence Study of Attention Deficit Hyperactivity Disorder and Its Comorbidities Among a Sample of Primary School Students in New Valley Governorate
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: ADHD
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2023-11-24
Enrollment: 200
Sex: ALL
Minimum age (years): 6
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: primary school students in New Valley governorate

Brief summary: Estimate the prevalence of attention deficit hyperactivity disorder and comorbid psychiatric disorder among primary school students in New Valley governorate.

Detailed description: ADHD (attention deficit hyperactivity disorder) is a common neurodevelopmental disorder characterized by hyperactivity, impulsivity, and inattention. Its prevalence ranges between 5.9 and 7.1% worldwide. Etiology of ADHD included combinations of genetic, neurological, and environmental factors. ADHD is more often a complex disorder with a high rate of associated comorbid conditions. Comorbid conditions are prevalent among people with ADHD and increase its burden and complexity of management. Children with ADHD are at a higher risk than children without ADHD for developing other psychiatric disorders. Most children with ADHD also have at least one comorbid condition, the presence of which contributes to poorer long-term outcomes. The pattern of comorbidities is influenced by age and sex; externalizing disorders are more common in younger ages and male participants, in contrast, internalizing disorders are more prevalent among older ages and female participants. Comorbidity involving ADHD and learning disorders is frequent, ranging from 25 to 40%. Other disorders likely to co-occur with ADHD are: bipolar disorders (11-75%), tic disorders (20%), obsessive compulsive disorders (6-15%). Children with ADHD may show several motor problems: longer and more variable reaction times, increased variability in speed and less accurate response reengagement, and impaired orienting responses, and increased number of responses with very long reaction times. Neurological soft sign have been associated with inattention and behavior difficulties for decades. Some researchers argue that these signs should be included in the diagnosis of ADHD.

Eligibility criteria: Inclusion Criteria:

Age: 6-17 years. Sex: both sexes will be included in the study.

Exclusion Criteria:

Age: less than 6 years or more than 17 years. Patients with major neurological deficits, cerebral palsy. Patient who refusing to participate in the study or their caregiver refusing to give informed consent. Mentally retarded children.

Primary outcomes:
measure: Detect the prevalence of attention deficit hyperactivity disorder among primary school students in New Valley governorate
timeFrame: Baseline
Secondary outcomes:
measure: Detect comorbid psychiatric disorder among ADHD primary school student in New Valley governorate.
timeFrame: Baseline
Other outcomes:
Locations:
Study officials:
References:
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