Clinical trial NCT06178276: Investigation of Neurophysiological Functioning During Oral Comprehension Task
Official title: Investigation of Neurophysiological Functioning During Oral Comprehension Task. An Exploratory Study in Second Language (Italian) Learning in French Students Using Autonomic and Cerebral Investigation
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Learning
Language
Comprehension
Keywords: Language Learning
Oral comprehension
autonomic activity
brain activity
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
Collaborators: name: University Grenoble Alps
name: Institut National de la Santé Et de la Recherche Médicale, France
First posted: 2023-12-20
Enrollment: 70
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: French learner in Italian language recruited at university

Brief summary: The oral comprehension (OC) of a second language (L2) involves different cognitive processes, specially during the learning phase. This study aims at investigating the neurophysiological functioning of different steps involved in this oral understanding.

Detailed description: Here, the investigators seek for the different neurophysiological processes involved in OC according to the level of understanding (2 levels) and its different phases (fluid, hindered and metacognitive feedback).

This study therefore requires three different research methodologies :

1. an interactive system dedicated to the boundary delimitations of obstacles during OC
2. an investigation of the autonomic nervous system responses (measurement of electrodermal activity and heart rate variability) that will likely occur differently during different phases of the OC process
3. an investigation of the central responses (through fMRI technique), coupled with autonomous responses, that will identify the different neural networks in the different stages of the OC process.

Eligibility criteria: Inclusion Criteria:

* French learner in Italian language
* right-handed
* affiliated to French social security
* informed consent signed

Exclusion Criteria:

* pregnant woman
* audiologic pathology impacting the capacity of hearing
* neurologic or psychiatric pathology that may interfere with oral comprehension
* learning disability (for instance: dyslexia)
* contra-indication to MRI and to EDA acquisition

Primary outcomes:
measure: Sympathetic activity
timeFrame: up to 3 months following the language profile completion
Secondary outcomes:
measure: Parasympathetic activity
timeFrame: up to 3 months following the language profile completion
measure: Activated brain regions demonstrating brain activity
timeFrame: up to 6 months following the language profile completion
measure: Correlations between sympathetic and parasympathetic activity
timeFrame: up to 3 months following the language profile completion
measure: Interaction between sympathetic activity and brain activity
timeFrame: up to 6 months following the acquisition of language profile
measure: Interaction between parasympathetic activity and brain activity
timeFrame: up to 6 months following the acquisition of language profile
measure: Linguistic evaluation
timeFrame: up to 1 month following the acquisition of language profile
measure: Cognitive evaluation of executive functions
timeFrame: up to 1 month following the acquisition of language profile
measure: Cognitive evaluation of short term memory
timeFrame: up to 1 month following the acquisition of language profile
Other outcomes:
Locations:
city: Grenoble
country: France
facility: University Hospital Grenoble
Study officials:
affiliation: University Grenoble Alpes
name: Triscia Biagiotti, Ms
role: STUDY_CHAIR
References: