Clinical trial NCT06266481: Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce POST in Shoulder Arthroscopic Surgeries: A Comparative Study
Official title: Topical Dexamethasone Versus Topical Lidocaine Spray to Reduce Post-intubation Sore Throat in Shoulder Arthroscopic Surgeries: A Comparative Study
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE2
PHASE3
Conditions: Postoperative Sore Throat
Keywords: Sore-throat postoperative
dexamesthsone
10% lidocaine
Lead sponsor: Pharos University in Alexandria
Sponsor class: OTHER
First posted: 2024-02-20
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted.

Detailed description: postoperative sore throat is the most frequent side effects after anaesthesia intubation. Dexamethasone and 10% lidocaine spray used prior to surgery has shown useful in managing these complications at the moment. In order to examine the prophylactic impact of local Dexamethasone and lidocaine on postoperative sore throat, this study was conducted.In this study, 100 patients were intubated to undergo general anaesthesia for shoulder arthroscopy and randomised into one of two groups. An endotracheal tube was soaked in 8mg of dexamethasone for the first group intubation, while 10% lidocaine was sprayed over the tube for the second group. Following extubation, the two groups examined the severity of sore throats

Eligibility criteria: Inclusion Criteria:

* •Patients belonging to ASA physical status I, II

  * Patients between age18 to 50 years
  * Patients belonging to both genders.
  * patients undergoing shoulder arthroscopic surgeries.
  * Patients with fasting blood glucose \&lt;100 mg/dl or random blood sugar \&lt;140 mg/dl.

Exclusion Criteria:

* Patients who are not willing to give consent for participation in the study

  * Patients with anticipated difficult airway
  * Patients who are allergic to steroids.
  * Patients with ASA physical status III, IV
  * Diabetic patients.
  * Patients on steroids
  * Patients requiring nasogastric tube or throat pack.
  * Patients posted for head and neck surgeries.
  * patient with GERD
  * Pregnant patients
  * preexisting upper respiratory tract infection.

Primary outcomes:
measure: Topical dexamethasone versus topical lidocaine spray to reduce post-intubation sore throat in shoulder arthroscopic surgeries: A comparative study
timeFrame: 3MONTH
Secondary outcomes:
Other outcomes:
Locations:
city: Alexandria
country: Egypt
facility: Pharos University
Study officials:
References:
citation: Lee JH, Kim SB, Lee W, Ki S, Kim MH, Cho K, Lim SH, Lee KM, Choi DN, Oh M. Effects of topical dexamethasone in postoperative sore throat. Korean J Anesthesiol. 2017 Feb;70(1):58-63. doi: 10.4097/kjae.2017.70.1.58. Epub 2016 Nov 25.
citation: Banihashem N, Alijanpour E, Hasannasab B, Zarei A. Prophylactic Effects of Lidocaine or Beclomethasone Spray on Post-Operative Sore Throat and Cough after Orotracheal Intubation. Iran J Otorhinolaryngol. 2015 May;27(80):179-84.
citation: Jabbar ML, Mahboba JH, Meazher N. Comparing the effectiveness of topical dexamethasone emollient, lidocaine gel, and glycerin emollient on the endotracheal tube for postoperative hoarseness of voice, sore throat, and laryngospasm. J Med Life. 2023 Jun;16(6):904-907. doi: 10.25122/jml-2022-0137.