Clinical trial NCT02382055: Changing Habits in Anorexia Nervosa: Novel Treatment Development
Official title: Changing Habits in Anorexia Nervosa
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anorexia Nervosa
Keywords: Eating Disorders
Psychotherapy
Anorexia Nervosa
Treatment
Lead sponsor: New York State Psychiatric Institute
Sponsor class: OTHER
First posted: 2015-03-06
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The investigators are examining what types of psychotherapy are most helpful for patients as they undergo weight restoration treatment for anorexia nervosa. In this study, patients who are receiving care on our inpatient unit will also receive 4 weeks of one two types of psychotherapy: Supportive Psychotherapy or Regulation Emotions and Changing Habits.

Detailed description: Patients will be receiving specialized inpatient treatment for anorexia nervosa on the Eating Disorders Unit at the New York State Psychiatric Institute, where care is provided free of charge.

Study procedures will begin after one week of acclimating to the inpatient unit. Patients will be randomly assigned to receive either Supportive Psychotherapy (focused on the transition to the inpatient unit) or REACH (focused on changing routines or habits that have become part of the eating disorder). Each treatment consists of 12-sessions, delivered 2-3 times per week.

Before and after treatment, patients will be asked to participate in interviews, questionnaires, and a lunch meal.

Eligibility criteria: Inclusion Criteria:

* DSM5 diagnosis of anorexia nervosa
* Age\>= 18
* Medically stable
* Able to provide informed consent

Exclusion Criteria:

* Other psychiatric disorder requiring acute treatment
* Serious medical illness
* Antipsychotic medication
* Severe cognitive impairment

Primary outcomes:
measure: Habit strength as measured by self report scales
timeFrame: 4 weeks
Secondary outcomes:
measure: Eating behavior as measured by laboratory meal
timeFrame: 4 weeks
measure: Eating behavior as measured by meal observation
timeFrame: 4 weeks
Other outcomes:
Locations:
city: New York
country: United States
facility: New York State Psychiatric Institute
state: New York
Study officials:
affiliation: New York State Psychiatric Institute
name: Joanna Steinglass, MD
role: PRINCIPAL_INVESTIGATOR
References:
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citation: McIntosh VV, Jordan J, Carter FA, Luty SE, McKenzie JM, Bulik CM, Frampton CM, Joyce PR. Three psychotherapies for anorexia nervosa: a randomized, controlled trial. Am J Psychiatry. 2005 Apr;162(4):741-7. doi: 10.1176/appi.ajp.162.4.741.
citation: McGowan L, Cooke LJ, Gardner B, Beeken RJ, Croker H, Wardle J. Healthy feeding habits: efficacy results from a cluster-randomized, controlled exploratory trial of a novel, habit-based intervention with parents. Am J Clin Nutr. 2013 Sep;98(3):769-77. doi: 10.3945/ajcn.112.052159. Epub 2013 Jul 17.
citation: Walsh BT. The enigmatic persistence of anorexia nervosa. Am J Psychiatry. 2013 May;170(5):477-84. doi: 10.1176/appi.ajp.2012.12081074.