Clinical trial NCT03343314: Effective Management of Calcific Aortic Stenosis in the Elderly
Official title: Effective Management of Calcific Aortic Stenosis in the Elderly
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Calcific Aortic Stenosis
Lead sponsor: French Cardiology Society
Sponsor class: OTHER
First posted: 2017-11-17
Enrollment: 1101
Sex: ALL
Minimum age (years): 75
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Multicenter study to prospectively include all patients who agreed to participate in the study, with severe and symptomatic aortic stenosis, and hospitalized in one of the medical-surgical centers participating in the study and offering all the therapeutic resources for the taking into account charge of patients with aortic stenosis

Brief summary: Although aortic valve replacement is recommended for any symptomatic severe calcific aortic stenosis, the therapeutic decision may be difficult. because of patient age and comorbidities.

Transcatheter Aortic Valve Implantation (TAVI) has recently extended the therapeutic indications in patients at high risk of surgery. However, the proportion of different treatments is not known in a contemporary population that can be treated according to the different resources currently available.

The scientific goal of this observational research is to evaluate intra-hospital therapeutic decision in elderly patients referred because of symptomatic severe aortic stenosis.

The one-year survival will be analyzed according to the therapeutic decision and the characteristics of the patients.


Eligibility criteria: Inclusion Criteria:

* Hospitalized due to symptomatic tight aortic stenosis (NYHA \>= II, dyspnea, angina or syncope);
* Having given his consent to participate in the study.

Exclusion Criteria:

* Non-severe aortic stenosis;
* Asymptomatic aortic stenosis;
* Patient under the age of 75;
* Patient refusing to participate in the study.

Primary outcomes:
measure: Collate the therapeutic decision (medical treatment, TAVI [Transcatheter Aortic Valve Implantation] or surgical aortic valve replacement) comprehensively for all hospitalized patients because of a severe, symptomatic RAC.
timeFrame: 1 day
Secondary outcomes:
measure: 1 year-survival
timeFrame: 1 year
Other outcomes:
Locations:
Study officials:
References:
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