Clinical trial NCT06254573: The Relationship Of Ultrasonographic Measurements With Sarcopenia in Stroke
Official title: The Relationship Of Distal Femoral Cartilage And Quadriceps Muscle Thickness With Functional Status And Sarcopenia İn Patients With Stroke
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hemiplegia
Keywords: Distal femoral cartilage thickness
Quadriceps muscle thickness
Functionality
Sarcopenia
Hemiplegia
Lead sponsor: Kayseri City Hospital
Sponsor class: OTHER_GOV
First posted: 2024-02-12
Enrollment: 48
Sex: ALL
Minimum age (years): 34
Maximum age (years): 89
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who applied to Kayseri City Hospital Physical Medicine and Rehabilitation outpatient clinic and were diagnosed with clinically and radiologically confirmed stroke caused by cerebrovascular disease were included in the study after their consent was obtained. Inclusion and exclusion criteria were stated below.

Brief summary: introduction:The aim of this study was to show the relationship of distal femoral cartilage and quadriceps thicknesses with functional status and presence of sarcopenia in ambulatory stroke patients with voluntary movement.

Materials and Method: Forty-eight patients who were diagnosed with stroke due to cerebrovascular disease, had started voluntary movement, and had a motor recovery of 3 or above according to Brunnstrom's Staging were included in this cross-sectional study.

Detailed description: Forty-eight patients who were diagnosed with stroke due to cerebrovascular disease, had started voluntary movement, and had a motor recovery of 3 or above according to Brunnstrom's Staging were included in this cross-sectional study. Bilateral distal femoral cartilage thickness and quadriceps femoris (rectus femoris+vastus intermedius) thickness were measured by ultrasonography. In addition, A Simple Questionnaire to Rapidly Diagnose Sarcopenia (SARC-F questionnaire), hand grip strength, muscle mass measurement with Dual energy X-ray absorptiometry (DXA), short physical performance battery (KFPB) tests were performed and the presence of sarcopenia The European Working Group on Sarcopenia in Older People-2 (EWGSOP- 2) were evaluated according to the criteria. Patients' Functional Independence Scale (FIM), Functional Ambulation Scale (FAS), Barthel Index and modified ashworth scale (MAS) were evaluated.

Eligibility criteria: Inclusion Criteria:

* Between 18 and 90 years old
* Presence of a history of ischemic or hemorrhagic stroke (based on CT and/or magnetic resonance imaging (MRI) report)
* Brunnstrom hemiplegia recovery staging, stage 3≥

Exclusion Criteria:

* History of recurrent cerebrovascular accident
* More than 2 years have passed since the history of cerebrovascular accident
* Inflammatory arthritis or any other rheumatic disease
* History of trauma to the knee (cruciate ligament or meniscus trauma)
* Previous knee surgery
* Pre-stroke neurological gait disorder
* Lower extremity amputation
* Knee joint contracture

Primary outcomes:
measure: Distal Femoral Cartilage Measurement
timeFrame: once at the beginning
measure: Quadriceps Femoris Muscle Thickness Measurement
timeFrame: once at the baseline
Secondary outcomes:
measure: Functional Independence Scale
timeFrame: once at the beginning
measure: Brunnstrom Stages of Stroke Recovery
timeFrame: once at the baseline
measure: Modified Ashworth Scale
timeFrame: once at the baseline
measure: Barthel Index for Activities of Daily Living
timeFrame: once at the baseline
measure: Functional Ambulation Scale
timeFrame: once at the baseline
measure: Evaluation of Muscle Mass
timeFrame: once at the baseline
measure: Evaluation of Muscle Performance
timeFrame: once at the beginning
measure: Evaluation of Muscle Strength
timeFrame: once at the baseline
Other outcomes:
Locations:
city: Talas
country: Turkey
facility: Health Sciences University, Kayseri Medicine Faculty
state: Kayseri
city: Kayseri
country: Turkey
facility: Health Sciences University, Kayseri Medicine Faculty
state: Kocasinan
Study officials:
affiliation: KAYSERİ CITY HOSPITAL
name: HAVVA TALAY ÇALIŞ
role: PRINCIPAL_INVESTIGATOR
References: