Clinical trial NCT04580212: Poultry Management and Child Diarrhea in Uganda
Official title: Improving Hygienic Management of Poultry in Rural Uganda
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Diarrhea
Lead sponsor: North Carolina State University
Sponsor class: OTHER
Collaborators: name: The Water Trust
First posted: 2020-10-08
Enrollment: 1307
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Fecal contamination from animal sources, specifically chickens, is increasingly recognized as a risk factor for enteric infections in low-income countries where domestic animals are often kept in close proximity to living quarters. Community members typically allow chickens to move freely around their compound and in their homes. Unlike other animals, such as cows or goats, poultry are typically not confined and their feces, which are relatively small, are considered relatively innocuous and therefore largely ignored by adults and children. In this study, the investigators have implemented an intervention to help rural poultry owners with children to hygienically separate chickens from children by focusing on a small set of key factors, including increased risk perception, increased perception of potential livelihood benefits, increased skills, and increased supportive social norms. The investigators hypothesized that the poultry hygiene intervention will lead to improved poultry management practices, which will in turn lead to reduced fecal contamination in the domestic environment and subsequently reduced diarrheal illness in young children. To measure these parameters along the causal chain, the investigators used a combination of household surveys, spot check observations and testing of environmental samples for fecal contamination.


Eligibility criteria: Inclusion Criteria:

* At least one person in the household is a member of Self-Help Groups formed by The Water Trust, Uganda
* There is at least one child under the age of 5 years living in the household
* There is an adult (\>18 years) primary caregiver of a child \<5 years available for participation in study

Exclusion Criteria:

* None

Primary outcomes:
measure: Prevalence of children <5 years with caregiver-reported diarrhea in past 7 days
timeFrame: Caregiver reported 7-day prevalence of diarrhea in children <5 years, measured approximately 1 year after initiation of intervention
Secondary outcomes:
measure: Proportion of households with E.coli in household environmental samples
timeFrame: Ascertained with analysis of samples from households, collected approximately 1 year after initiation of intervention
measure: Proportion of households with observed poultry feces in compound
timeFrame: Ascertained by spot check observation approximately 1 year after initiation of intervention
Other outcomes:
measure: Prevalence of children <5 years with caregiver-reported respiratory infection in past 7 days
timeFrame: Caregiver reported 7-day prevalence of respiratory infection in children <5 years, measured approximately 1 year after initiation of intervention
Locations:
city: Kampala
country: Uganda
facility: The Water Trust
Study officials:
affiliation: North Carolina State University
name: Ayse Ercumen
role: PRINCIPAL_INVESTIGATOR
affiliation: North Carolina State University
name: Angela Harris
role: PRINCIPAL_INVESTIGATOR
affiliation: The Water Trust
name: Chris Prottas
role: STUDY_DIRECTOR
References: