Clinical trial NCT00173160: Epidemiological Studies of Eating Disorders in Gifted Dance Students (2nd Year).
Official title: Epidemiological Studies of Eating Disorders in Gifted Dance Students: Prevalence Rate, Risk Factors and 1-Year Outcome (2nd Year).
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Eating Disorders
Keywords: Eating disorders
risk factors
prospective study
case-controled study
outcome
gifted dance students
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
Collaborators: name: National Science and Technology Council, Taiwan
First posted: 2005-09-15
Enrollment: 700
Sex: ALL
Minimum age (years): 17
Maximum age (years): 19
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: DEFINED_POPULATION
Time perspective: OTHER

Brief summary: This is the second-year part of a two-phase prospective epidemiological study as well as a community case-controled study. The aims of the second year study are firstly, to investigate the clinical course and 1-year outcome of eating disorders in the community, as well as the prospective risk factors of eating disorders; secondly, a case-control design involving with other psychiatric disorders from the same study population is used for risk factors study.

The study subjects are gifted dance high school students who participated the first-year study and are willing to participate the 2nd-year study (N=675). Screening questionnaires for eating disorders and general psychiatric disorders are EAT, BITE and CHQ-12. Other self-report questionnaires include perfectionism subscale of Eating Disorder Inventor-I (EDI), Rosenberg Self-esteem Scale (RSE), Eyseck Personality Scale, Pubertal Develoment Scale, and body figure test. Subjects who received interviews at the first-year study and those whose scores are above the threshold of the screening questionnaires need to receive interviews at 2nd phase. The criteria of interview threshold included EAT≧20+ BMI\<18.5Kg/m2, symptom scale of BITE ≧15 and/or severity scale of BITE≧5, and CHQ ≧4. The content of interview included structured diagnostic interview (SCID-IP 1995) as well as risk factors assessment. Each time a subject with bulimia nervosa was recruited, one matched control subject with no mental illness general psychiatric diagnosis was sought from the same class or school. Potential psychiatric control subjects were identified from their scores on the CHQ. The psychiatric control subjects were required to have no current or past eating disorders. The contents of risk factor assessments include personal vulnerability and family problems.

The relationships between individual risk factors and case status were assessed by univariate analysis. Conditional logistic analysis was used for multivariate analysis of risk factors prediction for eating disorders. To assess the relative importance of different types of exposure, the relationship between case status and exposure in each domain were first assessed by univariate analysis and then in multivariate stepwise regression analyses.

Detailed description: This is the second-year part of a two-phase prospective epidemiological study as well as a community case-controled study. The aims of the second year study are firstly, to investigate the clinical course and 1-year outcome of eating disorders in the community, as well as the prospective risk factors of eating disorders; secondly, a case-control design involving with other psychiatric disorders from the same study population is used for risk factors study.

The study subjects are Taiwanese gifted dance high school students.Parental informed consent for nonpartipation was delivered 3 days before study started. Screening questionnaires for eating disorders and general psychiatric disorders included EAT(Eating Attitude Test), BITE(Bulimic Investigatory Test, Ediburgh BITE) and CHQ-12(Chinese Health Questionnaire). Other self-report questionnaires include perfectionism subscale of Eating Disorder Inventor-I (EDI), Rosenberg Self-esteem Scale (RSE), Eyseck Personality Inventory, Pubertal Develoment Scale, and body figure test. Subjects who received interviews at the first-year study and those whose scores are above the threshold of the screening questionnaires need to receive interviews at 2nd phase. The criteria of interview threshold included EAT≧20+ BMI\<18.5Kg/m2, symptom scale of BITE ≧15 and/or severity scale of BITE≧5, and CHQ ≧4. The content of interview included structured diagnostic interview (SCID-IP 1995) as well as risk factors assessment. Each time a subject with bulimia nervosa was recruited, one matched control subject with no mental illness general psychiatric diagnosis was sought from the same class or school. Potential psychiatric control subjects were identified from their scores on the CHQ. The psychiatric control subjects were required to have no current or past eating disorders. The contents of risk factor assessments include personal vulnerability and family problems.

The relationships between individual risk factors and case status were assessed by univariate analysis. Conditional logistic analysis was used for multivariate analysis of risk factors prediction for eating disorders. To assess the relative importance of different types of exposure, the relationship between case status and exposure in each domain were first assessed by univariate analysis and then in multivariate stepwise regression analyses.

Eligibility criteria: Inclusion Criteria:

* gifted dance high school students.

Exclusion Criteria:

-

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital
Study officials:
affiliation: National Taiwan Univetsity Hospital
name: Mei-Chih Tseng, MD
role: PRINCIPAL_INVESTIGATOR
References: