Clinical trial NCT00185120: Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker
Official title: A Study on the Efficacy and Safety of Olmesartan Medoxomil and Its Combination With Hydrochlorothiazide Compared With an ACE Inhibitor and Its Combination With a Calcium Channel Blocker in Patients With Stage 2 Hypertension
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Hypertension
Keywords: Hypertension
angiotensin receptor blocker
calcium channel blocker
angiotensin converting enzyme inhibitor hydroclorothiazide
Lead sponsor: Daiichi Sankyo
Sponsor class: INDUSTRY
First posted: 2005-09-16
Enrollment: 152
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A comparison of 2 different combinations of high blood pressure medications to treat hypertension


Eligibility criteria: Inclusion Criteria:

* Greater than 18 years of age
* Patients with high blood pressure

Exclusion Criteria:

* Hypertensive encephalopathy, stroke or transient ischemic attack within the past 6 months
* History of myocardial infarction, percutaneous transluminal coronary revascularization, coronary artery bypass graft, and/or unstable angina pectoris within the past 6 months
* Type 1 diabetes mellitus

Primary outcomes:
measure: Change in systolic blood pressure from the start of the study
Secondary outcomes:
measure: Change in diastolic blood pressure from the start of the study
measure: Percent of patients who achieve target blood pressure goals
Other outcomes:
Locations:
city: Mobile
country: United States
state: Alabama
city: Long Beach
country: United States
facility: Memorial Research Medical Center
state: California
city: Los Angeles
country: United States
facility: National Research Institute
state: California
city: Roseville
country: United States
facility: Clinical Trials Research
state: California
city: Santa Ana
country: United States
facility: Apex Research Institute
state: California
city: Tustin
country: United States
facility: Orange County Research Center
state: California
city: Westlake Village
country: United States
facility: Westlake Medical Center
state: California
city: Coral Gables
country: United States
facility: Clinical Research of South Florida
state: Florida
city: Fort lauderdale
country: United States
facility: The Greater Fort Lauderdale Heart Group Research
state: Florida
city: Miami
country: United States
facility: SFBC International
state: Florida
city: Tamarac
country: United States
facility: CLIRECO, Inc.
state: Florida
city: Indianapolis
country: United States
facility: Midwest Institute for Clinical Research
state: Indiana
city: Wichita
country: United States
facility: Heartland Research Associates
state: Kansas
city: Auburn
country: United States
facility: Androscoggin Cardiology Research
state: Maine
city: Charlotte
country: United States
facility: Internal Medicine Associates of Charlotte
state: North Carolina
city: Winston-salem
country: United States
facility: Piedmont Medical Research Associates
state: North Carolina
city: Cincinnati
country: United States
facility: The Lindner Clinical Trial Center
state: Ohio
city: Warwick
country: United States
facility: Omega Medical Research
state: Rhode Island
city: Knoxville,
country: United States
facility: Volunteer Research Group, University of Tennessee Med. Ctr.
state: Tennessee
city: Carrollton
country: United States
facility: Punzi Medical Center
state: Texas
Study officials:
References: