Clinical trial NCT04492644: The Correlation Among Nutrition, Muscle Strength, Masticatory and Swallow Ability of Inpatient Elders
Official title: The Correlation Among Nutrition, Muscle Strength, Masticatory and Swallow Ability of Inpatient Elders
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Malnutrition; Moderate
Keywords: the elder inpatient,
nutritional assessment
handgrip strength
masticatory electromyography
Lead sponsor: China Medical University Hospital
Sponsor class: OTHER
Collaborators: name: China Medical University, China
First posted: 2020-07-30
Enrollment: 120
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: We enrolled 120 elderly inpatients in Asia University Hospital, Taiwan. We included new elderly inpatients aged 65 years or older who were able to communicate and were clearly conscious.

Brief summary: The masticatory performance would affect the nutritional status of elderly people. the prevalence of undernutrition among elderly inpatients is %20-50%. Previous related studies investigate the masticatory performance with special chewing gum and self-reported questionnaires. This study observes the correlation of masticatory muscles sEMG, nutritional status, and handgrip force among elderly inpatients.

Detailed description: In this cross-sectional study, we enrolled 120 seniors aged 65 and above who are newly admitted to the Asian University Hospital. Within 24 hours they admitted to the hospital, we collected the Mini Nutritional Assessment scores, surface electromyography data, handgrip strength, self-assessment swallowing ability score, and clinical objective data. We performed the statistics for independent t-test, Pearson correlation analysis, and binary logistic regression with SPSS 23 software.

Eligibility criteria: Inclusion Criteria:

* new elderly inpatients aged 65 years or older who were able to communicate and were clearly conscious

Exclusion Criteria:

* Elderly individuals who were diagnosed with gastrointestinal (GI) dysfunction, dysphagia, edentulism without rehabilitation with dentures, brain disease, stroke or cancer were excluded due to the possibility of dysphagia, cachexia or masticatory muscle palsy.

Primary outcomes:
measure: masticatory muscle surface EMG
timeFrame: Data were collected after the participants signed the informed consent form within 24 hours admitted to hospital.
Secondary outcomes:
measure: Nutritional status
timeFrame: Data were collected after the participants signed the informed consent form within 24 hours admitted to hospital.
Other outcomes:
measure: Handgrip force
timeFrame: Data were collected after the participants signed the informed consent form within 24 hours admitted to hospital.
Locations:
city: Taichung
country: Taiwan
facility: Asia University
Study officials:
affiliation: Asia University
name: Yin-Hwa Shih, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Alzahrani SH, Alamri SH. Prevalence of malnutrition and associated factors among hospitalized elderly patients in King Abdulaziz University Hospital, Jeddah, Saudi Arabia. BMC Geriatr. 2017 Jul 3;17(1):136. doi: 10.1186/s12877-017-0527-z.
citation: Berretin-Felix G, Nary Filho H, Padovani CR, Trindade Junior AS, Machado WM. Electromyographic evaluation of mastication and swallowing in elderly individuals with mandibular fixed implant-supported prostheses. J Appl Oral Sci. 2008 Mar-Apr;16(2):116-21. doi: 10.1590/s1678-77572008000200007.
citation: Gomes F, Baumgartner A, Bounoure L, Bally M, Deutz NE, Greenwald JL, Stanga Z, Mueller B, Schuetz P. Association of Nutritional Support With Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk: An Updated Systematic Review and Meta-analysis. JAMA Netw Open. 2019 Nov 1;2(11):e1915138. doi: 10.1001/jamanetworkopen.2019.15138.