Clinical trial NCT05323695: Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand
Official title: Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Depressive Symptoms
Keywords: Depression
Transgender women
Lead sponsor: Thai Red Cross AIDS Research Centre
Sponsor class: OTHER
Collaborators: name: amfAR, The Foundation for AIDS Research
name: National Institutes of Health (NIH)
name: Fogarty International Center of the National Institute of Health
First posted: 2022-04-12
Enrollment: 317
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The study aims to develop and implement a depression screening intervention into routine HIV and sexual health service provision at a transgender health clinic in Thailand, and to explore the facilitators, barriers, feasibility and acceptability of the screening implementation.

Detailed description: The study will follow a mixed-methods approach that will incorporate quantitative and qualitative components. Aim 1 will involve the development and implementation of depression screening intervention at Tangerine Clinic. Aim 2 will involve semi-structured interviews with a purposive subset of participants who received the intervention and healthcare providers to explore the multilevel facilitators, barriers, feasibility and acceptability of the screening implementation. Aim 3 will evaluate the proportion of participants who are offered, accept, and receive the peer-led depression screening intervention, and the proportion who screen positive.

Eligibility criteria: Inclusion Criteria:

1. Thai nationality
2. Transgender women ≥18 years
3. Attending the Tangerine Clinic for routine care visits during the intervention period.
4. Can be a new or returning clients.

Exclusion Criteria:

1. Transgender women currently receiving care for a mental health diagnosis will be excluded from participating in this study.

Inclusion Criteria for healthcare providers:

1. Currently working at the Tangerine Clinic
2. Can be medical doctors, nurses, peer counselors and other members of the clinic management team involved in the routine delivery of HIV and health services to Transgender women.

Exclusion criteria for healthcare providers

1. Not willing to participate in this study

Primary outcomes:
measure: Intervention Acceptability: Number of participants who accepted intervention
timeFrame: Day 1
measure: Intervention Acceptability: Participants' perspective of the intervention through in-depth interviews
timeFrame: Day 1
measure: Intervention Acceptability: Participants' perspective of the intervention through focus group discussion
timeFrame: Day 1
measure: Intervention Feasibility: Number of intervention completed
timeFrame: Day 1
measure: Intervention Feasibility: Participants' perspective of the intervention through in-depth interviews
timeFrame: Day 1
measure: Intervention Feasibility: Participants' perspective of the intervention through focus group discussion.
timeFrame: Day 1
measure: Number of participants screening positive for depression
timeFrame: Day 1
Secondary outcomes:
Other outcomes:
Locations:
city: Pathum Wan
country: Thailand
facility: Institute of HIV Research and Innovation
state: Bangkok
Study officials:
affiliation: Institute of HIV Research and Innovation
name: Rena Janamnuaysook
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Poteat T, Scheim A, Xavier J, Reisner S, Baral S. Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People. J Acquir Immune Defic Syndr. 2016 Aug 15;72 Suppl 3(Suppl 3):S210-9. doi: 10.1097/QAI.0000000000001087.
citation: Rodriguez-Munoz MF, Castelao Legazpi PC, Olivares Crespo ME, Soto Balbuena C, Izquierdo Mendez N, Ferrer Barrientos FJ, Huynh-Nhu L. [PHQ-2 as First Screening Instrument of Prenatal Depression in Primary Health Care, Spain]. Rev Esp Salud Publica. 2017 Jan 30;91:e201701010. Spanish.
citation: Martinez P, Soto-Brandt G, Brandt S, Guajardo V, Rojas G. [Validation of patient health Questionnaire-2 to detect depressive symptoms in diabetic or hypertensive patients]. Rev Med Chil. 2020 Nov;148(11):1614-1618. doi: 10.4067/S0034-98872020001101614. Spanish.
citation: Baral S, Logie CH, Grosso A, Wirtz AL, Beyrer C. Modified social ecological model: a tool to guide the assessment of the risks and risk contexts of HIV epidemics. BMC Public Health. 2013 May 17;13:482. doi: 10.1186/1471-2458-13-482.