Clinical trial NCT01457755: Gilead Sustained Virologic Response (SVR) Registry
Official title: A Long Term Follow-up Registry for Subjects Who Achieve a Sustained Virologic Response to Treatment in Gilead-Sponsored Trials in Subjects With Chronic Hepatitis C Infection
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Hepatitis C, Chronic
Keywords: Hepatitis C
HCV
Sustained Virologic Response
Direct Acting Antiviral
Combination Therapy
Tegobuvir
Registry
HCV RNA
Treatment experienced
Treatment naive
GS 9451
GS 5885
GS 7977
GS 5816
Sofosbuvir
Sovaldi™
SOF
Ledipasvir
LDV
Lead sponsor: Gilead Sciences
Sponsor class: INDUSTRY
First posted: 2011-10-24
Enrollment: 6625
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Participants who have achieved sustained virologic response (SVR) while participating in a previous Gilead sponsored HCV study.

Brief summary: This Registry is designed to provide long term clinical and virologic follow up in participants who have achieved sustained virologic response (SVR) while participating in a previous Gilead sponsored hepatitis C virus (HCV) study. This long term follow up study is observational and no treatment is provided for HCV.


Eligibility criteria: Key Inclusion Criteria:

* Have previously participated in a Gilead-sponsored hepatitis C study and received at least one Gilead oral antiviral agent (OAV)
* Have achieved SVR in a Gilead-sponsored study, as defined in the original treatment protocol
* Provide written, informed consent
* Be willing and able to comply with the visit schedule and protocol-mandated procedures

Key Exclusion Criteria:

* Individuals planning to start a new course of hepatitis C therapy including any investigational drug or device during the course of the follow-up Registry
* History of clinically significant illness or any other major medical disorder that may interfere with follow up, assessments, or compliance with the protocol

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Primary outcomes:
measure: Proportion of participants maintaining SVR at Week 144 by treatment regimen
timeFrame: Week 144
Secondary outcomes:
measure: Proportion of participants with detectable HCV RNA due to reemergence of preexisting virus through Week 144 by treatment regimen
timeFrame: Up to 144 weeks
measure: Proportion of participants with detectable HCV resistance mutations through Week 144 by treatment regimen
timeFrame: Up to 144 weeks
measure: Proportion of participants with detectable HCV RNA due to reinfection through Week 144 by treatment regimen
timeFrame: Up to 144 weeks
measure: Liver disease progression
timeFrame: Up to 144 weeks
measure: Proportion of participants who develop hepatocellular carcinoma (HCC) through Week 144 by treatment regimen
timeFrame: Up to 144 weeks
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: Birmingham Gastroenterology Associates
state: Alabama
city: Birmingham
country: United States
facility: University of Alabama at Birmingham
state: Alabama
city: Dothan
country: United States
facility: Digestive Health Specialists of the Southeast, PA
state: Alabama
city: Phoenix
country: United States
facility: Mayo Clinic
state: Arizona
city: Tucson
country: United States
facility: The University of Arizona
state: Arizona
city: Anaheim
country: United States
facility: Advanced Clinical Research Institute, LLC
state: California
city: Bakersfield
country: United States
facility: Franco Felizarta, MD
state: California
city: Coronado
country: United States
facility: Southern California Liver Centers
state: California
city: Costa Mesa
country: United States
facility: West Coast Clinical Trials, LLC
state: California
city: La Jolla
country: United States
facility: Scripps Clinic Medical Group
state: California
city: La Mesa
country: United States
facility: eStudySite
state: California
city: Long Beach
country: United States
facility: Long Beach VA Medical Center
state: California
city: Los Angeles
country: United States
facility: Ruane Clinical Research Group
state: California
city: Los Angeles
country: United States
facility: National Research Institute
state: California
city: Los Angeles
country: United States
facility: Anthony Mills MD, Inc
state: California
city: Los Angeles
country: United States
facility: Cedars-Sinai Medical Center
state: California
city: Los Angeles
country: United States
facility: Kaiser Permanente
state: California
city: Los Angeles
country: United States
facility: Veterans Administration Wadsworth Medical Center
state: California
city: Oceanside
country: United States
facility: eStudySite
state: California
city: Palo Alto
country: United States
facility: Stanford University
state: California
city: Pasadena
country: United States
facility: Huntington Medical Research Institutes
state: California
city: Rialto
country: United States
facility: Inland Empire Liver Foundation
state: California
city: Sacramento
country: United States
facility: University of California Davis Medical Center
state: California
city: Sacramento
country: United States
facility: UC Davis Medical Center
state: California
city: San Diego
country: United States
facility: University of California at San Diego
state: California
city: San Diego
country: United States
facility: Research and Education, Inc.
state: California
city: San Diego
country: United States
facility: Medical Associates Research Group, Inc.
state: California
city: San Diego
country: United States
facility: Kaiser Permanente
state: California
city: San Diego
country: United States
facility: University of California San Diego
state: California
city: San Francisco
country: United States
facility: California Pacific Medical Center
state: California
city: San Francisco
country: United States
facility: Quest Clinical Research
state: California
city: San Francisco
country: United States
facility: Kaiser Permanente Center
state: California
city: San Jose
country: United States
facility: Silicon Valley Research Institute
state: California
city: Torrance
country: United States
facility: Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center
state: California
city: Aurora
country: United States
facility: University of Colorado Hospital
state: Colorado
city: Englewood
country: United States
facility: South Denver Gastroenterology
state: Colorado
city: Hamden
country: United States
facility: Gastroenterology Center of Connecticut
state: Connecticut
city: New Haven
country: United States
facility: Yale University
state: Connecticut
city: Washington
country: United States
facility: Georgetown University Medical Center
state: District of Columbia
city: Washington
country: United States
facility: Whitman-Walker Health
state: District of Columbia
city: Washington
country: United States
facility: Capital Medical Associates, P.C.
state: District of Columbia
city: Bradenton
country: United States
facility: Bach and Godofsky Infectious Diseases
state: Florida
city: Coral Gables
country: United States
facility: University of Miami - Dept of Neurology
state: Florida
city: Gainesville
country: United States
facility: University of Florida Hepatology Research at CTRB
state: Florida
city: Jacksonville
country: United States
facility: Borland-Groover Clinic
state: Florida
city: Miami
country: United States
facility: University of Miami
state: Florida
city: New Port Richey
country: United States
facility: Advanced Research Institute
state: Florida
city: Orlando
country: United States
facility: Orlando Immunology Center
state: Florida
city: Orlando
country: United States
facility: Internal Medicine Specialists
state: Florida
city: Orlando
country: United States
facility: Orlando Clinical Research Center
state: Florida
city: Tampa
country: United States
facility: Saint Joseph's Hospital
state: Florida
city: Tampa
country: United States
facility: Tampa General Hospital
state: Florida
city: Wellington
country: United States
facility: South Florida Center of Gastroenterology, P.A.
state: Florida
city: Atlanta
country: United States
facility: Atlanta Gastroenterology Associates
state: Georgia
city: Atlanta
country: United States
facility: The Emory Clinic
state: Georgia
city: Atlanta
country: United States
facility: Digestive Healthcare of Georgia
state: Georgia
city: Atlanta
country: United States
facility: Atlanta Medical Center
state: Georgia
city: Decatur
country: United States
facility: Dekalb Gastroenterology Associates, LLC
state: Georgia
city: Decatur
country: United States
facility: Infectious Disease Specialists of Atlanta, PC
state: Georgia
city: Marietta
country: United States
facility: Gastrointestinal Specialists of Georgia, PC
state: Georgia
city: Honolulu
country: United States
facility: The Queen's Medical Center-Liver Center
state: Hawaii
city: Chicago
country: United States
facility: Ruth M. Rothstein CORE Center
state: Illinois
city: Chicago
country: United States
facility: University of Chicago
state: Illinois
city: Chicago
country: United States
facility: Northwestern Memorial Hospital
state: Illinois
city: Indianapolis
country: United States
facility: Indianapolis Gastroenterology Research Foundation
state: Indiana
city: Indianapolis
country: United States
facility: Indiana University School of Medicine
state: Indiana
city: Kansas City
country: United States
facility: University of Kansas Medical Center
state: Kansas
city: Bowling Green
country: United States
facility: Graves-Gilbert Clinic
state: Kentucky
city: Bastrop
country: United States
facility: Delta Research Partners, LLC
state: Louisiana
city: Baton Rouge
country: United States
facility: Medical Development Centers, LLC
state: Louisiana
city: Baton Rouge
country: United States
facility: Gastroenterology Associates, LLC
state: Louisiana
city: Baltimore
country: United States
facility: Mercy Medical Center
state: Maryland
city: Baltimore
country: United States
facility: Digestive Disease Associates, PA
state: Maryland
city: College Park
country: United States
facility: University of Maryland
state: Maryland
city: Lutherville
country: United States
facility: Johns Hopkins University
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
city: Boston
country: United States
facility: Beth Israel Deaconess Medical Center
state: Massachusetts
city: Boston
country: United States
facility: Community Research Initiative of New England
state: Massachusetts
city: Burlington
country: United States
facility: Lahey Clinic Medical Center
state: Massachusetts
city: Springfield
country: United States
facility: The Research Institute
state: Massachusetts
city: Worcester
country: United States
facility: Partners in Internal Medicine, PC
state: Massachusetts
city: Worcester
country: United States
facility: University of Massachusetts
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan Medical Center
state: Michigan
city: Detroit
country: United States
facility: Henry Ford Health System
state: Michigan
city: Rochester
country: United States
facility: Mayo Clinic
state: Minnesota
city: Saint Paul
country: United States
facility: Minnesota Gastroenterology
state: Minnesota
city: Tupelo
country: United States
facility: Digestive Health Specialists
state: Mississippi
city: Kansas City
country: United States
facility: Kansas City Research Institute, LLC
state: Missouri
city: Kansas City
country: United States
facility: The Kansas City Free Health Clinic
state: Missouri
city: Saint Louis
country: United States
facility: Washington University School of Medicine
state: Missouri
city: Saint Louis
country: United States
facility: Saint Louis University
state: Missouri
city: Berlin
country: United States
facility: Comprehensive Clinical Research
state: New Jersey
city: Hillsborough
country: United States
facility: ID Care, Inc.
state: New Jersey
city: Morristown
country: United States
facility: Atlantic Research Affiliates, LLC
state: New Jersey
city: Newark
country: United States
facility: Saint Michael's Medical Center
state: New Jersey
city: Vineland
country: United States
facility: The Gastroenterology Group of South Jersey
state: New Jersey
city: Albuquerque
country: United States
facility: University of New Mexico
state: New Mexico
city: Santa Fe
country: United States
facility: Southwest C.A.R.E. Center
state: New Mexico
city: Binghamton
country: United States
facility: Binghamton Gastroenterology Associates, PC
state: New York
city: Bronx
country: United States
facility: Bronx Veteran's Affairs Medical Center
state: New York
city: Manhasset
country: United States
facility: Northwell Health
state: New York
city: Manhasset
country: United States
facility: Northwell Health
state: New York
city: New York
country: United States
facility: Concorde Medical Group PLLC
state: New York
city: New York
country: United States
facility: Weill Cornell Medical College of Cornell Univeristy
state: New York
city: New York
country: United States
facility: St. Luke's Roosevelt Hospital
state: New York
city: New York
country: United States
facility: Columbia Presbyterian Hospital, Columbia University
state: New York
city: New York
country: United States
facility: Icahn School of Medicine at Mount Sinai
state: New York
city: Rochester
country: United States
facility: University of Rochester
state: New York
city: Yonkers
country: United States
facility: Westchester Digestive Disease Group
state: New York
city: Asheville
country: United States
facility: Asheville Gastroenterology Associates, P.A.
state: North Carolina
city: Chapel Hill
country: United States
facility: University of North Carolina at Chapel Hill
state: North Carolina
city: Chapel Hill
country: United States
facility: University of North Carolina
state: North Carolina
city: Charlotte
country: United States
facility: Carolinas Medical Center
state: North Carolina
city: Durham
country: United States
facility: Duke University Medical Center
state: North Carolina
city: Fayetteville
country: United States
facility: Cumberland Research Associates, LLC
state: North Carolina
city: Statesville
country: United States
facility: Carolinas Center for Liver Disease
state: North Carolina
city: Winston-Salem
country: United States
facility: Digestive Health Specialists, PA
state: North Carolina
city: Cincinnati
country: United States
facility: University of Cincinnati
state: Ohio
city: Tulsa
country: United States
facility: Options Health Research LLC
state: Oklahoma
city: Medford
country: United States
facility: Schleinitz Research and Gastroenterology LLC
state: Oregon
city: Portland
country: United States
facility: Oregon Health & Science University
state: Oregon
city: Allentown
country: United States
facility: Lehigh Valley Health Network, Network Office of Research and Innovation
state: Pennsylvania
city: Lancaster
country: United States
facility: Regional Gastroenterology Associates of Lancaster, Ltd.
state: Pennsylvania
city: Philadelphia
country: United States
facility: University of Pennsylvania Hospital
state: Pennsylvania
city: Philadelphia
country: United States
facility: Philadelphia FIGHT
state: Pennsylvania
city: Philadelphia
country: United States
facility: University of Pennsylvania School of Medicine
state: Pennsylvania
city: Pittsburgh
country: United States
facility: UPMC Center For Liver Diseases
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Veterans Affairs Pittsburgh Healthcare System
state: Pennsylvania
city: Providence
country: United States
facility: University Gastroenterology
state: Rhode Island
city: Providence
country: United States
facility: The Miriam Hospital
state: Rhode Island
city: Germantown
country: United States
facility: Memphis Gastroenterology Group
state: Tennessee
city: Germantown
country: United States
facility: Gastro One
state: Tennessee
city: Nashville
country: United States
facility: The Frist Clinic
state: Tennessee
city: Nashville
country: United States
facility: Nashville Medical Research Institute
state: Tennessee
city: Nashville
country: United States
facility: Quality Medical Research, PLLC
state: Tennessee
city: Arlington
country: United States
facility: The North Texas Clinical Research Institute
state: Texas
city: Austin
country: United States
facility: Central Texas Clinical Research, LLC
state: Texas
city: Dallas
country: United States
facility: UT Southwestern Medical Center
state: Texas
city: Dallas
country: United States
facility: Baylor Endocrine Center
state: Texas
city: Dallas
country: United States
facility: UT Southwestern Medical Center at Dallas
state: Texas
city: Dallas
country: United States
facility: Methodist Dallas Medical Center
state: Texas
city: Dallas
country: United States
facility: Southwest Infectious Disease Clinical Research, Inc
state: Texas
city: Houston
country: United States
facility: Therapeutic Concepts, PA
state: Texas
city: Houston
country: United States
facility: Kelsey Research Foundation
state: Texas
city: Houston
country: United States
facility: Research Specialists of Texas
state: Texas
city: Houston
country: United States
facility: St. Luke's Health Baylor College of Medicine Medical Center
state: Texas
city: Houston
country: United States
facility: University of Texas Health Science Center at Houston
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine
state: Texas
city: Houston
country: United States
facility: CHI Health Reseach Center
state: Texas
city: Live Oak
country: United States
facility: Gastroenterology Consultants PLC
state: Texas
city: San Antonio
country: United States
facility: The Texas Liver Institute
state: Texas
city: Murray
country: United States
facility: Intermountain Medical Center
state: Utah
city: Salt Lake City
country: United States
facility: University of Utah
state: Utah
city: Salt Lake City
country: United States
facility: PRA Health Sciences
state: Utah
city: Annandale
country: United States
facility: Metropolitan Research
state: Virginia
city: Falls Church
country: United States
facility: Inova Fairfax Hospital Center for Liver Diseases
state: Virginia
city: Newport News
country: United States
facility: Liver Institute of Virginia
state: Virginia
city: Norfolk
country: United States
facility: Digestive and Liver Disease Specialists
state: Virginia
city: Richmond
country: United States
facility: Virginia Commonwealth University Medical Center
state: Virginia
city: Seattle
country: United States
facility: Virginia Mason Medical Center
state: Washington
city: Seattle
country: United States
facility: Harborview Medical Center
state: Washington
city: Madison
country: United States
facility: University of Wisconsin Hospital and Clinics
state: Wisconsin
city: Canberra
country: Australia
facility: Canberra Specialist Centre
state: Australian Capital Territory
city: Camperdown
country: Australia
facility: Royal Prince Alfred Hospital
state: New South Wales
city: Concord
country: Australia
facility: Concord Repatriation General Hospital
state: New South Wales
city: Darlinghurst
country: Australia
facility: East Sydney Doctors
state: New South Wales
city: Darlinghurst
country: Australia
facility: Holdsworth House Medical Practice
state: New South Wales
city: Darlinghurst
country: Australia
facility: St Vincent's Public Hospital Sydney
state: New South Wales
city: Kogarah
country: Australia
facility: St George Hospital
state: New South Wales
city: Liverpool
country: Australia
facility: Liverpool Hospital
state: New South Wales
city: Westmead
country: Australia
facility: Westmead Hospital
state: New South Wales
city: Adelaide
country: Australia
facility: Royal Adelaide Hospital
state: South Australia
city: Bedford Park
country: Australia
facility: Flinders University
state: South Australia
city: Clayton
country: Australia
facility: Monash Medical Centre
state: Victoria
city: Fitzroy
country: Australia
facility: St. Vincent's Hospital Melbourne
state: Victoria
city: Footscray
country: Australia
facility: Footscray Hospital
state: Victoria
city: Heidelberg
country: Australia
facility: Austin Health
state: Victoria
city: Melbourne
country: Australia
facility: Alfred Hospital
state: Victoria
city: Melbourne
country: Australia
facility: Alfred Hospital
state: Victoria
city: Parkville
country: Australia
facility: The Royal Melbourne Hospital
state: Victoria
city: Fremantle
country: Australia
facility: Fremantle Hospital
state: Western Australia
city: Murdoch
country: Australia
facility: Fiona Stanley Hospital
state: Western Australia
city: Greenslopes
country: Australia
facility: Greenslopes Private Hospital
city: Herston
country: Australia
facility: Royal Brisbane & Women's Hospital
city: Nedlands
country: Australia
facility: Sir Charles Gairdner Hospital
city: Perth
country: Australia
facility: Royal Perth Hospital
city: Woolloongabba
country: Australia
facility: Princess Alexandra Hospital
city: Graz
country: Austria
facility: Medizinische Universität Graz
state: Styria
city: Wien
country: Austria
facility: Medizinische Universität Wien
state: Vienna
city: Wien
country: Austria
facility: Wilhelminenspital der Stadt Wien
state: Vienna
city: Antwerpen
country: Belgium
facility: Ziekenhuis Netwerk Antwerpen Campus Stuivenberg
city: Brussels
country: Belgium
facility: Cliniques Universitaires Saint Luc
city: Brussels
country: Belgium
facility: Université Libre de Bruxelles Hôpital Erasme
city: Kortrijk
country: Belgium
facility: AZ Groeninge Kortrijk
city: Calgary
country: Canada
facility: University of Calgary Liver Unit
state: Alberta
city: Edmonton
country: Canada
facility: University of Alberta Hospital
state: Alberta
city: Vancouver
country: Canada
facility: Liver and Intestinal Research Center
state: British Columbia
city: Vancouver
country: Canada
facility: GIRI GI Research Institute
state: British Columbia
city: Vancouver
country: Canada
facility: Gordon and Leslie Diamond Health Care Centre
state: British Columbia
city: Vancouver
country: Canada
facility: Vancouver Infectious Disease Research and Care Centre
state: British Columbia
city: Winnipeg
country: Canada
facility: University of Manitoba
state: Manitoba
city: Ottawa
country: Canada
facility: Ottawa General Hospital
state: Ontario
city: Toronto
country: Canada
facility: Toronto General Hospital
state: Ontario
city: Toronto
country: Canada
facility: Toronto Western Hospital
state: Ontario
city: Toronto
country: Canada
facility: Toronto Liver Centre
state: Ontario
city: Montreal
country: Canada
facility: Centre Hospitalier de L'Universite de Montreal (CHUM)
state: Quebec
city: Opava
country: Czechia
facility: Slezska nemocnice v Opave, Infekcni oddeleni
city: Praha 4
country: Czechia
facility: Remedis, s.r.o.
city: Praha 6
country: Czechia
facility: Klin med, s.r.o.
city: Talinn
country: Estonia
facility: West Tallinn Central Hospital
city: Tartu
country: Estonia
facility: Tartu University Hospital
city: Clermont-Ferrand
country: France
facility: Centre Hospitalier Universitaire de Clermont-Ferrand
state: Auvergne
city: CRETEIL Cedex
country: France
facility: Hôpital Henri Mondor
state: Ile-de-france
city: Paris Cedex 12
country: France
facility: Hôpital Saint-Antoine
state: Ile-de-france
city: Paris cedex 12
country: France
facility: Hôpital Saint-Antoine
state: Ile-de-france
city: Paris Cedex 13
country: France
facility: CHU Pitié-Salpêtrière
state: Ile-de-france
city: Paris cedex 18
country: France
facility: Hôpital Bichat-Claude Bernard
state: Ile-de-france
city: Paris Cedex 20
country: France
facility: Hôpital Tenon
state: Ile-de-france
city: Villejuif Cedex
country: France
facility: Hôpital Paul Brousse
state: Ile-de-france
city: Vandoeuvre-les-Nancy
country: France
facility: Hopitaux De Brabois
state: Limousin, Lorraine
city: Limoges Cedex
country: France
facility: Centre Hospitalier Universitaire (CHU) De Limoges - Hopital Dupuytren
state: Limousin
city: Toulouse
country: France
facility: CIC Hopital Purpan
state: Midi-pyrenees
city: Toulouse
country: France
facility: CIC Hopital Purpan
state: Midi-pyrenees
city: Lille
country: France
facility: Hôpital Claude Huriez- Service d'Hépato-Gastroentérologie
state: NORD Pas-de-calais
city: Marseille cedex 08
country: France
facility: Hôpital-Saint Joseph, Service D'Hépato-Gastroentérologie
state: Provence Alpes COTE D'azur
city: Nice
country: France
facility: Hôpital de I´Archet 2
state: Provence Alpes COTE D'azur
city: Cedex 9
country: France
facility: Centre Hospitalier Universitaire de Grenoble
state: Rhone-alpes
city: Clichy Cedex
country: France
facility: Hopital Beaujon
city: Montpellier
country: France
facility: Hopital Saint-Eloi
city: Nice cedex 3
country: France
facility: CHU de Nice - Hôpital l'Archet
city: Paris, Cedex 14
country: France
facility: Hôpital Cochin
city: Paris
country: France
facility: Hôpital Saint Louis
city: Paris
country: France
facility: Hôpital la Pitié Salpêtrière
city: Pessac Cedex
country: France
facility: Centre Hospitalier Universitaire Bordeaux Hôpital Haut-Lévêque
city: Rennes Cedex 9
country: France
facility: Hopital Pontchaillou
city: Strasbourg
country: France
facility: C.H.U. Strasbourg
city: Freiburg im Breisgau
country: Germany
facility: PraxisZentrum für Gastroenterologie und Endokrinologie
state: Baden-wuerttemberg
city: Freiburg
country: Germany
facility: Albert-Ludwigs-Universität
state: Baden-wuerttemberg
city: Heidelberg
country: Germany
facility: Medizinische Universitätsklinik IV (Krehl Klinik) Abt. Gastroenterologie und Infektionskrankhen
state: Baden-wuerttemberg
city: München
country: Germany
facility: Medizinische Klinik und Poliklinik III
state: Bayern
city: Frankfurt am Main
country: Germany
facility: Infektiologikum Frankfurt
state: Hessen
city: Frankfurt am Main
country: Germany
facility: Universitätsklinikum Frankfurt
state: Hessen
city: Düsseldorf
country: Germany
facility: Medizinisches Versorgungszentrum
state: Nordrhein-westfalen
city: Düsseldorf
country: Germany
facility: Universitätsklinikum Düsseldorf
state: Nordrhein-westfalen
city: Essen
country: Germany
facility: Universitätsklinikum Essen
state: Nordrhein-westfalen
city: Herne
country: Germany
facility: Gastroenterologische Gemeinschaftspraxis
state: Nordrhein-westfalen
city: Köln
country: Germany
facility: Klinikum der Universität zu Köln
state: Nordrhein-westfalen
city: Muenster
country: Germany
facility: Centrum für Interdisziplinäre Medizin
state: Nordrhein-westfalen
city: Berlin
country: Germany
facility: Leber- and Studienzentrum am Checkpoint
city: Berlin
country: Germany
facility: EPIMED GmbH
city: Berlin
country: Germany
facility: Charité Universitätsmedizin Berlin
city: Berlin
country: Germany
facility: Zentrum für Infektiologie Berlin Prenzlauer Berg GmbH
city: Bonn
country: Germany
facility: Universitäts Bonn
city: Frankfurt
country: Germany
facility: Universitätsklinikum Frankfurt
city: Hamburg
country: Germany
facility: Asklepios Klinik St. Georg
city: Hamburg
country: Germany
facility: Universitatsklinikum Hamburg-Eppendorf
city: Hannover
country: Germany
facility: Medizinische Hochschule Hannover
city: Kiel
country: Germany
facility: Gastroenterologische Gemeinschaftspraxis Kiel Preetzer
city: Leipzig
country: Germany
facility: University of Leipzig
city: Mainz
country: Germany
facility: Mainz University
city: San Giovanni Rotondo
country: Italy
facility: Ospedale Casa Sollievo della Sofferenza
state: Foggia
city: Bergamo
country: Italy
facility: Azienda Ospedaliera Papa Giovanni XXIII
city: Bologna
country: Italy
facility: Azienda Ospedaliera di Bologna - Policlinico S. Orsola Malpighi
city: Bologna
country: Italy
facility: Azienda Ospedaliera S. Orsola - Malpighi
city: Genova
country: Italy
facility: Ente Ospedaliero Ospedali Galliera di Genova
city: Milano
country: Italy
facility: Ospedale San Raffaele-IRCCS, Centro San Luigi - San Raffaele Turro, Unità Operativa di Malattie Infettive
city: Milano
country: Italy
facility: Azienda Ospedaliera - Polo Universitario Luigi Saco
city: Milano
country: Italy
facility: Azienda Ospedaliera Ospedale Niguarda Ca' Granda
city: Milano
country: Italy
facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
city: Padova
country: Italy
facility: Azienda Ospedaliera Padova, U.O.C. Cardiologia
city: Palermo
country: Italy
facility: Azienda Ospedaliera-universitaria Policlinico P. Giaccone
city: Parma
country: Italy
facility: Azienda Ospedaliero Universitaria di Parma
city: Roma
country: Italy
facility: Instituto Nationale Per Le Malattie Infettive "Lazzaro Spallanzani"
city: Roma
country: Italy
facility: Fondazione Policlinico Tor Vergata
city: Torino
country: Italy
facility: Azienda Ospedaliera Città della Salute e della Scienza di Torino
city: Amsterdam
country: Netherlands
facility: Academisch Medisch Centrum
state: Noord-holland
city: Leiden
country: Netherlands
facility: Leiden Universitair Medisch Centrum
state: Zuid-holland
city: Rotterdam
country: Netherlands
facility: Erasmus Medisch Centrum
state: Zuid-holland
city: Nijmegen
country: Netherlands
facility: Universitair Medisch Centrum Sint Radboud
city: Grafton
country: New Zealand
facility: Auckland Clinical Studies Limited
state: Auckland
city: Grafton
country: New Zealand
facility: Auckland City Hospital
state: Auckland
city: Tauranga
country: New Zealand
facility: Bay of Plenty Clinical School
state: BAY OF Plenty
city: Newtown
country: New Zealand
facility: Wellington Hospital
state: WGN
city: Christchurch
country: New Zealand
facility: Christchurch Hospital
city: Dunedin
country: New Zealand
facility: Dunedin Hospital
city: Hamilton
country: New Zealand
facility: Urosurgery
city: Wroclaw
country: Poland
facility: Centrum Badan Klinicznych
state: Dolnoslaskie
city: Warszawa
country: Poland
facility: SP ZOZ Wojewódzki Szpital Zakazny
state: Mazowieckie
city: Bialystok
country: Poland
facility: Wojewódzki Szpital Specjalistyczny im. Kazimierza Dluskiego w Bialymstoku
state: Podlaskie
city: Chorzów
country: Poland
facility: Szpital Specjalistyczny w Chorzowie
state: Slaskie
city: Myslowice
country: Poland
facility: ID Clinic Arkadiusz Pisula
state: Slaskie
city: Lodz
country: Poland
facility: Spzoz Wojewodzki Specjalistyczny Szpital im. W. Bieganskiego W Lodzi
city: San Juan
country: Puerto Rico
facility: Fundacion De Investigacion De Diego
city: San Juan
country: Puerto Rico
facility: Clinical Research Puerto Rico
city: Majadahonda
country: Spain
facility: Hospital Puerta de Hierro Majadahonda
state: Madrid
city: Málaga
country: Spain
facility: Hospital Clínico Universitario Virgen de la Victoria
state: Malaga
city: Barcelona
country: Spain
facility: Hospital Clinic I Provincial de Barcelona
city: Barcelona
country: Spain
facility: Hospital Clinic I Provincial de Barcelona
city: Madrid
country: Spain
facility: Hospital General Universitario Gregorio Marañon
city: Madrid
country: Spain
facility: Hospital Universitario 12 de Octubre
city: Madrid
country: Spain
facility: Hospital Universitario La Paz
city: Madrid
country: Spain
facility: Hospital Ramón y Cajal
city: Madrid
country: Spain
facility: Hospital Universitario La Paz
city: Santander
country: Spain
facility: Hospital Universitario Marques de Valdecilla
city: Sevilla
country: Spain
facility: Hospital Universitario Nuestra Señora de Valme
city: Sevilla
country: Spain
facility: Hospital Universitario Nuestra Señora de Valme
city: Valencia
country: Spain
facility: Hospital General Universitario de Valencia
city: Göteborg
country: Sweden
facility: Sahlgrenska Universitetssjukhuset, Östra Sjukhus
city: Lund
country: Sweden
facility: Skånes Universitetssjukhus i Lund
city: Malmö
country: Sweden
facility: Skånes Universitetssjukhus,
city: Stockholm
country: Sweden
facility: Karolinska University Hospital Huddinge
city: Birmingham
country: United Kingdom
facility: University of Birmingham and Queen Elizabeth Hospital Birmingham
state: England
city: Bristol
country: United Kingdom
facility: Bristol Royal Infirmary
state: England
city: London
country: United Kingdom
facility: St George Hospital
state: England
city: London
country: United Kingdom
facility: Chelsea and Westminster Hospital NHS Foundation Trust
state: England
city: London
country: United Kingdom
facility: Guy's and Saint Thomas NHS Foundation Trust
state: England
city: London
country: United Kingdom
facility: Imperial College Healthcare NHS Trust
state: England
city: London
country: United Kingdom
facility: King's College Hospital
state: England
city: London
country: United Kingdom
facility: Royal Free London NHS Foundation Trust
state: England
city: Manchester
country: United Kingdom
facility: North Manchester General Hospital
state: England
city: Nottingham
country: United Kingdom
facility: Nottingham University Hospitals NHS Trust
state: England
city: Oxford
country: United Kingdom
facility: John Radcliffe Hospital
state: England
city: Plymouth
country: United Kingdom
facility: Derriford Hospital
state: England
city: Portsmouth
country: United Kingdom
facility: Queen Alexandra Hospital
state: England
city: Southampton
country: United Kingdom
facility: Southampton University Hospitals NHS Trust, Southampton General Hospital
state: England
Study officials:
affiliation: Gilead Sciences
name: Gilead Study Director
role: STUDY_DIRECTOR
References:
citation: Younossi ZM, Stepanova M, Racila A, Afendy A, Lawitz EJ, Schwabe C, Ruane PJ, Lalezari J, Reddy KR, Jacobson IM, Muir AJ, Gaggar A, Myers RP, Younossi I, Nader F. Long-term Benefits of Sustained Virologic Response for Patient-Reported Outcomes in Patients With Chronic Hepatitis C Virus Infection. Clin Gastroenterol Hepatol. 2020 Feb;18(2):468-476.e11. doi: 10.1016/j.cgh.2019.07.047. Epub 2019 Jul 31.