Clinical trial NCT03588260: Respiratory Muscle Strength in Patients With Idiopathic Pulmonary Fibrosis
Official title: Respiratory Muscle Strength in Patients With Idiopathic Pulmonary Fibrosis: The Relationship With Exercise Capacity, Physical Activity Level, and Quality of Life
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Idiopathic Pulmonary Fibrosis
Keywords: idiopathic pulmonary fibrosis
respiratory muscle strength
physical activity
quality of life
dyspnea
fatigue severity
exercise capacity
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2018-07-17
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The patients who have agreed to participate in the study from patients diagnosed with idiopathic pulmonary fibrosis referred to the center of pulmonary rehabilitation from the interstitial lung disease polyclinic will be included in the study. In addition, a healthy adult control group will be established from similar age groups. The two groups will be compared in terms of outcome measures.

Brief summary: Respiratory muscle strength, dyspnea perception, physical activity and quality of life measurements will be performed and groups will be compared in two groups consisting of patients with idiopathic pulmonary fibrosis referred to pulmonary rehabilitation clinic and healthy volunteers in similar age range.

Detailed description: The patients who have agreed to participate in the study from patients diagnosed with idiopathic pulmonary fibrosis referred to the center of pulmonary rehabilitation from the interstitial lung disease polyclinic will be included in the study. In addition, a healthy adult control group will be established from similar age groups. The two groups will be compared in terms of outcome measures.The study outcome measurements are maximum inspiratory/expiratory muscle strength , international physical activity questionaire, modified Medical Research Council dyspnea scale, Short form 36 quality of lide questionaire, fatigue severity scale, six minute walking test.

Eligibility criteria: Inclusion Criteria:

* Between the ages of 18-70
* Patients signing informed consent form
* Patients diagnosed with idiopathic pulmonary fibrosis.

Exclusion Criteria:

* Patients who use steroids for less than 1 year
* The patient does not want to participate in the study

Primary outcomes:
measure: Maximum inspiratory muscle pressure
timeFrame: 15 minutes
measure: Maximum expiratory muscle pressure
timeFrame: 15 minutes
measure: The distance covered in six-minute walk test
timeFrame: 10 minutes
measure: International Physical Activity Questionnaire
timeFrame: 15 minutes
measure: The Quality of Life Questionaire
timeFrame: 20 minutes
Secondary outcomes:
measure: The modified Medical Research Council (mMRC) scale
timeFrame: 3 minutes
measure: The fatigue severity scale
timeFrame: 15 minutes
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Yedikule Chest Disease Hospital
state: Zeytinburnu
Study officials:
References: