Clinical trial NCT02638350: Performance Evaluation of Clinical Ultrasound in Management of Acute Pulmonary Edema in Elderly Patient
Official title: Performance Evaluation of Clinical Ultrasound in Management of Acute Pulmonary Edema in Elderly Patient Over 65 Years, Admitted to a Host of Vital Emergency Services
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pulmonary Edema
Respiratory Distress Syndrome
Keywords: lung ultrasound
Pulmonary Edema
Respiratory Distress Syndrome
Lead sponsor: University Hospital, Toulouse
Sponsor class: OTHER
First posted: 2015-12-23
Enrollment: 123
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: The main objective is to assess the validation of the diagnosis early acute pulmonary edema in elderly patients with acute respiratory distress, admitted in a host of vital emergency services by lung ultrasound associated with the measurement of the inferior vena cava.


Eligibility criteria: Inclusion Criteria:

* Patient with compatible episode with acute edema (tachypnea with respiratory rate\> 25/min and/or oxygen saturation on room air \<90%, auscultation, dyspnea, sudden onset of symptoms)

Exclusion Criteria:

* Vital signs of distress requiring intubation tracheal immediately
* Myocardial infarction lower seat with extension to the right ventricle, in the acute phase

Primary outcomes:
measure: The result of lung ultrasound associated with the measurement of the inferior vena cava.
timeFrame: 2 hours
Secondary outcomes:
measure: Number of the proportion of appropriate and inappropriate treatment.
timeFrame: 2 hours
measure: The duration of the medical care.
timeFrame: 2 hours
Other outcomes:
Locations:
city: Toulouse
country: France
facility: University Hospital Toulouse
state: Midi Pyrenees
Study officials:
affiliation: University Hospital, Toulouse
name: Thibault Le Gourrierec, MD
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Melniker LA, Leibner E, McKenney MG, Lopez P, Briggs WM, Mancuso CA. Randomized controlled clinical trial of point-of-care, limited ultrasonography for trauma in the emergency department: the first sonography outcomes assessment program trial. Ann Emerg Med. 2006 Sep;48(3):227-35. doi: 10.1016/j.annemergmed.2006.01.008. Epub 2006 Mar 24.
citation: Nielsen LS, Svanegaard J, Wiggers P, Egeblad H. The yield of a diagnostic hospital dyspnoea clinic for the primary health care section. J Intern Med. 2001 Nov;250(5):422-8. doi: 10.1046/j.1365-2796.2001.00901.x.
citation: Ray P, Birolleau S, Lefort Y, Becquemin MH, Beigelman C, Isnard R, Teixeira A, Arthaud M, Riou B, Boddaert J. Acute respiratory failure in the elderly: etiology, emergency diagnosis and prognosis. Crit Care. 2006;10(3):R82. doi: 10.1186/cc4926. Epub 2006 May 24.
citation: McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Kober L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Ronnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A; ESC Committee for Practice Guidelines. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2012 Jul;33(14):1787-847. doi: 10.1093/eurheartj/ehs104. Epub 2012 May 19. No abstract available.