Clinical trial NCT04579055: Impact of Chair Seat Height on the 1-Minute Sit to Stand Test Performance in Chronic Obstructive Pulmonary Disease
Official title: The Impact of Chair Seat Height on the 1-Minute Sit to Stand Test Performance in Chronic Obstructive Pulmonary Disease: a Randomized Cross-over Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: COPD
Chronic Obstructive Pulmonary Disease
Keywords: 1-minute Sit to Stand Test
chair seat height
Lead sponsor: Berner Reha Zentrum AG
Sponsor class: OTHER
Collaborators: name: University of Zurich
First posted: 2020-10-08
Enrollment: 55
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: OTHER

Brief summary: The 1-minute sit to stand (1-min STS) test is a standardized test which is used to examine exercise capacity in patients with chronic obstructive pulmonary disease (COPD). The chair seat height used is standardized to 46-48 cm. Using a standard seat height for all patients - irrespective of their body height - may lead to invalid estimates of functional exercise capacity. The objective of this study is to assess whether there is a difference in repetitions during the 1-min STS test if the seat height is adjusted to 90° knee joint angle or the standard height chair of 46 cm is used.

Detailed description: In a single-center, randomized crossover study, the investigators aim to elucidate whether there is a difference in repetitions during the 1-min STS test if the seat height is adjusted to 90° knee joint angle or the standard height chair of 46 cm is used.

Patients with COPD referred for pulmonary rehabilitation will be invited to perform one standardised- (chair seat height 46cm) and one individualized (chair seat height adapted to 90° knee flexion) 1-min STS test on two different days in random order.

The tests will be performed after patients are familiarised with the 1-min STS testing procedure and learning effects can be excluded.

Eligibility criteria: Inclusion Criteria:

* Patients with diagnosed COPD according to a forced expiratory volume in 1s (FEV1) / forced vital capacity (FVC) ratio below the lower limit of normal

Exclusion Criteria:

* Patients who are not able to bend their knees while sitting on a standard chair (i.e., knee flexion less than 90°)
* Patients who are not able to understand the instructions of the 1-min STS test, either of language or cognitive reasons
* Patients who are unable to perform the STS test due to functional disability (i.e., being not able to rise from a chair without hand support), previous surgery, or pain according to the judgement of the responsible physician.
* Patients who did not sign the informed consent form

Primary outcomes:
measure: Number of repetitions in the 1-min STS test
timeFrame: During pulmonary rehabilitation, approximately 14 days
Secondary outcomes:
measure: Sit to stand power index
timeFrame: During pulmonary rehabilitation, approximately 14 days
Other outcomes:
measure: Oxygen saturation
timeFrame: During pulmonary rehabilitation, approximately 14 days
measure: Heart rate
timeFrame: During pulmonary rehabilitation, approximately 14 days
measure: Ratings of perceived exertion
timeFrame: During pulmonary rehabilitation, approximately 14 days
measure: Ratings of perceived breathlessness
timeFrame: During pulmonary rehabilitation, approximately 14 days
measure: Incorrectly performed repetitions during the 1-min STS test
timeFrame: During pulmonary rehabilitation, approximately 14 days
measure: Questionnaire about the patient's preferences during the 1-min sit to stand test
timeFrame: During pulmonary rehabilitation, approximately 14 days
Locations:
city: Heiligenschwendi
country: Switzerland
facility: Berner Reha Zentrum
state: Bern
Study officials:
affiliation: Berner Reha Zentrum, Heiligenschwendi
name: Thomas Riegler, MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Zurich
name: Thomas Radtke, PD, Dr phil
role: PRINCIPAL_INVESTIGATOR
References:
citation: Crook S, Busching G, Schultz K, Lehbert N, Jelusic D, Keusch S, Wittmann M, Schuler M, Radtke T, Frey M, Turk A, Puhan MA, Frei A. A multicentre validation of the 1-min sit-to-stand test in patients with COPD. Eur Respir J. 2017 Mar 2;49(3):1601871. doi: 10.1183/13993003.01871-2016. Print 2017 Mar.
citation: Yoshioka S, Nagano A, Hay DC, Fukashiro S. Peak hip and knee joint moments during a sit-to-stand movement are invariant to the change of seat height within the range of low to normal seat height. Biomed Eng Online. 2014 Mar 12;13(1):27. doi: 10.1186/1475-925X-13-27.
citation: Reychler G, Boucard E, Peran L, Pichon R, Le Ber-Moy C, Ouksel H, Liistro G, Chambellan A, Beaumont M. One minute sit-to-stand test is an alternative to 6MWT to measure functional exercise performance in COPD patients. Clin Respir J. 2018 Mar;12(3):1247-1256. doi: 10.1111/crj.12658. Epub 2017 Jun 15.
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