Clinical trial NCT03398408: Cognitive Flexibility Training in Persistent Pain
Official title: Cognitive Flexibility Training in Persistent Pain
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Pain
Lead sponsor: Washington University School of Medicine
Sponsor class: OTHER
Collaborators: name: Lumos Labs, Inc.
First posted: 2018-01-12
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: To determine whether participation in a cognitive training program over a training period of five weeks improves cognitive flexibility in patients with chronic hip, knee, and back pain.

Detailed description: This project is a single-center prospective, randomized study to assess whether cognitive flexibility can be improved through training on a Lumosity®-based training module over the course a five week timeframe in patients with chronic hip, knee, and back pain; and whether changes in cognitive flexibility will correlate with perceived pain scores.

Eligibility criteria: Inclusion Criteria:

* Adults age 18 to 70 with chronic hip, knee, or low back pain for \>3 months
* Documented moderate to severe chronic pain
* English as a primary language
* Access to a computer at home and an email account

Exclusion Criteria:

* Diagnosed Alzheimer's or documented severe cognitive impairment
* Lack of email/lack of basic computer skills
* Has undergone an interventional pain procedure within one week prior to enrollment
* Are scheduled to undergo a pain procedure during the five weeks of complete cognitive training

Primary outcomes:
measure: Does cognitive training over five weeks improve cognitive flexibility performance scores in chronic hip, knee, and back pain patients?
timeFrame: Up to 5 months
Secondary outcomes:
Other outcomes:
Locations:
city: Saint Louis
country: United States
facility: Washington University in St. Louis
state: Missouri
Study officials:
affiliation: Washington University School of Medicine
name: Simon Haroutounian, PhD
role: PRINCIPAL_INVESTIGATOR
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