Clinical trial NCT02232295: A Clinical Trial to Study the Effect of Imagined Progressive Movements in Patients With Paralysis of One Side of the Body.
Official title: To Study the Effect of Graded Motor Imagery on Upper Limb Motor Functions and Quality of Life in Patients With Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: Upper extremity, motor imagery, mirror therapy
Lead sponsor: Maharishi Markendeswar University (Deemed to be University)
Sponsor class: OTHER
First posted: 2014-09-05
Enrollment: 26
Sex: ALL
Minimum age (years): 45
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the Study to evaluate the effect of Graded motor imagery on upper limb motor functions and quality of life in patients with stroke that was conducted in two centers in india. The primary outcome measures were upper limb motor functions at 6 weeks and secondary outcome measure was quality of life at 6 weeks.

Research Hypothesis: There would be significant effect of GMI on Upper limb motor functions and quality of life in patients with stroke.

Detailed description: Graded Motor Imagery (GMI) is essentially a brain based treatment, targeting the activation of different brain regions in a graded manner. GMI is a three stage treatment programme comprising of Left Right discrimination training, Explicit Motor imagery and Mirror therapy.

In this Study, GMI approach is applied on the patients with Stroke to enhance their Upper limb motor functions and Quality of life.

Conventional treatment:

Patients of group A and group B had received conventional treatment for 6 weeks. Conventional treatment consists of Task oriented upper extremity functional exercises. Components of Task oriented training include weight bearing, supportive reactions, and reaching, grasping, holding and release activities. It was performed five days a week for six weeks of one hour duration.

Graded Motor Imagery:

Patients of group A had received GMI programme with conventional treatment for 6 weeks. It is a three stage process, was performed five days a week for six weeks of one hour duration. It comprises of:

* Left Right discrimination training (Implicit Motor Imagery) - 2 weeks
* Explicit Motor Imagery (Imagined movements) - 2 weeks
* Mirror Therapy - 2 weeks

Eligibility criteria: Inclusion Criteria:

* Age (between 45 to 65 years)
* Individuals who experienced one episode of stroke only.
* Both males and females were included in the study
* Both ischemic \& haemorrhagic stroke individuals were included in the study
* Duration of stroke between 1 to 6 months
* Mini mental status examination (MMSE) (score \> 23)
* Patients with Brunnstrom stage 1 \& 2

Exclusion Criteria:

* Individuals having any musculoskeletal disorders
* Individuals having any neurological disorder other than stroke
* Individuals with any visual impairment
* Individuals having any systemic disease
* Non cooperative patients
* Patients suffering from psychological problems

Primary outcomes:
measure: Upper limb motor functions
timeFrame: six weeks
Secondary outcomes:
measure: Quality of life
timeFrame: 6 weeks
Other outcomes:
Locations:
city: Ambala
country: India
facility: Maharishi Markandeshwar institute of Physiotherapy and rehabilitation, MMU, Mullana
state: Haryana
Study officials:
affiliation: Maharishi Markandeshwar University, Mullana-Ambala
name: Manisha Uttam, Masters in Physiotherapy
role: PRINCIPAL_INVESTIGATOR
References: