Clinical trial NCT06515808: Effects of Three Airway Instruments on the Incidence of Postoperative Sore Throat
Official title: Effects of GlideScope, Pentax Airway Scope, and Macintosh Blade on the Incidence of Postoperative Sore Throat: A Cohort Study of 10,382 Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Sore-throat
Keywords: Glidescope
Macintosh Blade
Airway Scope
Postoperative sore throat
General Anesthesia
Lead sponsor: Fu Jen Catholic University Hospital
Sponsor class: OTHER
First posted: 2024-07-23
Enrollment: 10382
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who underwent inpatient surgeries and general anesthesia with endotracheal tubes, intubated with direct laryngoscope, Pentax AirwayScope or GlideScope, during the period from January 1, 2018, to December 30, 2019, were included for the analysis.

Brief summary: Postoperative sore throat (POST) is a common complaint after general anesthesia. POST is defined by the presence of a self-reported foreign body sensation or a painful sensation in the throat after general anesthesia. This condition may affect recovery and patient satisfaction and is associated with many factors, including intubation tools. Previous studies have reported conflicting results on POST. This retrospective cohort study, with sample size of 10,382 patients, was conducted to confirm the hypothesis that the use of video laryngoscopy (VL) is associated with a lower incidence of POST compared with direct laryngoscopy (DL).

Detailed description: Background: Postoperative sore throat (POST) is a common complaint after general anesthesia. POST is defined by the presence of a self-reported foreign body sensation or a painful sensation in the throat after general anesthesia. This condition may affect recovery and patient satisfaction and is associated with many factors, including intubation tools. Previous studies have reported conflicting results on POST. This retrospective cohort study, with sample size of 10,382 patients, was conducted to confirm the hypothesis that the use of video laryngoscopy (VL) is associated with a lower incidence of POST compared with direct laryngoscopy (DL).

Methods: Data were extracted from a prospectively maintained quality improvement database. A total of 10,382 patients were included in the study. Statistical analysis was conducted for comparisons of demographic characteristics and to determine the effect of intubation tools on the incidence of POST.

Eligibility criteria: Inclusion Criteria:

* Patients receiving inpatients surgery and general anesthesia with tracheal intubation

Exclusion Criteria:

* Having difficult airway,

  * Anticipated difficult airway:

    1. Abnormal cervical spine movement or temporomandibular joint movement
    2. Airway-compromising masses such as tumors, cysts, or hematomas
    3. A Mallampati score greater than 3
    4. A thyromental distance of less than 6 cm
    5. A lesion below vocal cord
    6. A previously identified difficult airway
  * Unexpected difficult airway

    1. difficult mask ventilation
    2. difficult vocal cord visualization after multiple attempts of laryngoscopy
* Receiving laryngeal surgery, such as laryngeal biopsy, laryngeal microsurgery, laryngoplasty or vocal cord surgery,
* Not being extubated at the end of anesthesia,
* Being pregnant,
* Being under 20 years of age,
* American Society of Anesthesiologists (ASA) physical status class greater than 3.

Primary outcomes:
measure: Postoperative sore throat (POST)
timeFrame: 12 to 24 hours after general anesthesia is finished
Secondary outcomes:
Other outcomes:
Locations:
city: New Taipei City
country: Taiwan
facility: Fu Jen Catholic University Hospital
Study officials:
affiliation: Fu Jen Catholic University Hospital, Fu Jen Catholic University
name: Chao Hsien Sung, MD
role: PRINCIPAL_INVESTIGATOR
References: