Clinical trial NCT05812508: Comparison Between Bare Scleral Technique and Conjunctival Auto-graft on Corneal Topography After Pterygium Surgery
Official title: A Comparative Study Between Bare Scleral Technique and Conjunctival Autograft on Corneal Topography After Pterygium Surgery
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Corneal Topography
Keywords: pterygium surgery by bare scleral & autograft
Lead sponsor: Sohag University
Sponsor class: OTHER
First posted: 2023-04-13
Enrollment: 30
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with pterygium not associated with other pathologies in the eye (suitable for excision) .

Brief summary: Aim of the work:

To study the corneal topographic pattern changes in patients who have pterygium excision by two surgical techniques (bare sclera, conjunctival autograft).

Detailed description: Pterygium is one of the common ocular surface disorders , it's is an elastotic triangular fibro-vascular tissue covered by conjunctival epithelium that spreads over the cornea. Pterygium causes differences in curvature \& power across the cornea .

The prevalence of pterygium varies from 1.1% to 53% globally in different environmental conditions. Risk factors include;UV radiation, geographical latitude near to the equator, outdoor activity , aging, male, and dusty environment.

Pterygium excision is important in patients suffering from blurred vision due to astigmatism . Surgical techniques include ; bare sclera excision, conjunctival autograft, conjunctival transpositional flap, and amniotic membrane grafting. Pterygium excision increases in the mean central corneal curvature \& reduces astigmatism that leads to improvement in visual acuity.

Corneal topography is a gold standard in corneal pathology follow-up. Corneal topography is a computer assisted diagnostic tool that creates a three-dimensional map of the surface curvature of the cornea. Corneal topography produces a detailed, visual description of the shape and power of the cornea.

In this study , corneal topography is used to detect how does corneal curvature change after excision of pterygium .

Eligibility criteria: Inclusion Criteria:-

* Patients with pterygium not associated with other pathologies (suitable for excision).
* Nasal pterygium extended to the cornea.

Exclusion Criteria: -

* Associated pathologies such as glaucoma, and cataract.
* Corneal opacities or irregularities, scars, dystrophy or ectasia.
* Patients who underwent previous corneal surgery (including refractive surgery)
* Pseudo-pterygium.

Primary outcomes:
measure: comparison of topography finding after pterygium surgery by the bare scleral technique.
timeFrame: baseline
measure: comparison of topography finding after pterygium surgery by the conjunctival auto-graft technique.
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Yilmaz S, Yuksel T, Maden A. Corneal topographic changes after four types of pterygium surgery. J Refract Surg. 2008 Feb;24(2):160-5. doi: 10.3928/1081597X-20080201-06.