Clinical trial NCT05483881: the Effects of Air Pollution on Respiratory Diseases in Children
Official title: A Multicenter Observational Study of the Effects of Air Pollution on Respiratory Diseases in Children
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Respiratory Disease
Keywords: Respiratory Diseases
children
air pollution
Lead sponsor: Beijing Children's Hospital
Sponsor class: OTHER
Collaborators: name: Tianjin Children's Hospital
name: Jiangxi Province Children's Hospital
name: Wuhan Children's Hospital
name: Capital Institute of Pediatrics, China
name: First Affiliated Hospital of Xinjiang Medical University
name: Guangzhou Women and Children's Medical Center
name: The First Affiliated Hospital of Anhui Medical University
name: Shanxi Provincial Maternity and Children's Hospital
name: The First Affiliated Hospital of Xiamen University
name: Shenzhen Children's Hospital
name: Xian Children's Hospital
name: The First Affiliated Hospital of Guangzhou Medical University
name: China-Japan Friendship Hospital
name: Kunming Children's Hospital
name: Xianyang Children's Hospital
First posted: 2022-08-02
Enrollment: 2000000
Sex: ALL
Minimum age (years): 1
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All children aged between 0-18 years who visited Beijing Children's hospital or other hospitals participating in the project due to respiratory diseases from 2010 to 2021.

Brief summary: The investigators expect to reveal the association between air pollution and childhood respiratory diseases through a multi-center observational study, and summarize the relationship between air pollution and childhood respiratory diseases.

Detailed description: The investigators will collect the data of outpatient and emergency children in Beijing Children's hospital and other participating hospitals due to respiratory diseases from 2010 to 2021, , collect clinical data and basic information, obtain air pollution data and meteorological monitoring data and perform data processing and statistical analysis,，then analyzes the impact of air pollution on children's respiratory diseases.

Eligibility criteria: Inclusion Criteria:

* All children participating in this clinical study must meet all of the following criteria:

  1. Age: 0-18 years old, male and female
  2. Consultation for respiratory diseases
  3. Visit time is between 2010-2021
  4. Provide complete personally identifiable information and medical information

Exclusion Criteria:

* All children with any of the following conditions must be excluded from this study:

  1. children who visit hospital don't for respiratory diseases
  2. children participating in this clinical study don't provide complete personally identifiable information and medical information
  3. Visit time is not between 2010-2021.

Primary outcomes:
measure: Major air pollutant concentrations
timeFrame: 12 years
Secondary outcomes:
measure: Number of daily visits for respiratory diseases in outpatient and emergency departments
timeFrame: 12 years
Other outcomes:
Locations:
city: Beijing
country: China
facility: Baoping Xu
state: Beijing
Study officials:
References: