Clinical trial NCT04991727: Evaluation of Protective Pulmonary Ventilation by Pulmonary Ultrasound
Official title: Pulmonary Ultrasound to Evaluate Protective Lung Ventilation in Obese Patients With Postoperative Pulmonary Complications Impact
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Assessment
Keywords: lung ultrasound
Protective pulmonary ventilation
Postoperative pulmonary complications
Lead sponsor: General Hospital of Ningxia Medical University
Sponsor class: OTHER
First posted: 2021-08-05
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients undergoing elective surgery, non-cardiac surgery, in the Heart and Brain Hospital of Ningxia Medical University from June, 2021 to October, 2023

Brief summary: Peri - operative ultrasonography was used to evaluate the effects of protective lung ventilation on the postoperative lungs of obese patients.The purpose of this study was to apply ultrasound lung ventilation area score to the monitoring of pulmonary complications in patients with postoperative obesity.To verify the reliability and practicability of perioperative lung ultrasound quantitative scoring.

Detailed description: Ultrasound lung ventilation area score was applied to monitor the pulmonary complications of patients after obesity operation to verify the perioperative period.

The reliability and practicability of quantitative lung ultrasound score to clarify the effect of protective lung ventilation under perioperative pulmonary ultrasound monitoring on obesity patients.To guide the management of mechanical ventilation under general anesthesia and the prevention and treatment of postoperative pulmonary complications

Eligibility criteria: Inclusion Criteria:

* enrollment of patients aged 18 years or above；
* Eligible adult patients had an American Society of Anesthesiologists (ASA) physical status classification of I to IV
* undergoing elective or expedited nonurgent, noncardiac surgery with general anesthesia

Exclusion Criteria:

* patient refusal;
* morbid obesity (BMI \>40 kg/ m²);
* American Society of Anesthesiologists (ASA) physical status categories IV-V;
* previous intrathoracic procedure;
* severechronic obstructive pulmonary disease (forced expiratory volume in 1 s \<30% of the predicted value;
* a contraindication to radial artery cannulation.

Primary outcomes:
measure: Lung ultrasound scoring
timeFrame: in the morning of the first day
Secondary outcomes:
measure: Results of arterial blood gas analysis
timeFrame: entering the operating room, in the morning of the first day ,the second day , the third day after surgery
measure: Mechanical ventilation parameter
timeFrame: entering the operating room, in the morning of the first day ,the second day , the third day after surgery
Other outcomes:
Locations:
city: Yinchuan
country: China
facility: General Hospital of Ningxia Medical University
state: Ningxia
Study officials:
References:
citation: Wanguemert Perez AL. Clinical applications of pulmonary ultrasound. Med Clin (Barc). 2020 Apr 10;154(7):260-268. doi: 10.1016/j.medcli.2019.11.001. Epub 2020 Jan 8. English, Spanish.
citation: Costamagna A, Pivetta E, Goffi A, Steinberg I, Arina P, Mazzeo AT, Del Sorbo L, Veglia S, Davini O, Brazzi L, Ranieri VM, Fanelli V. Clinical performance of lung ultrasound in predicting ARDS morphology. Ann Intensive Care. 2021 Mar 29;11(1):51. doi: 10.1186/s13613-021-00837-1.