Clinical trial NCT03790527: Cognitive Bias Modification Training on Internet Gaming Disorder
Official title: A Research on the Mechanism of Cognitive Bias Modification Training in Internet Gaming Disorders.
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Internet Gaming Disorder
Lead sponsor: Beijing Normal University
Sponsor class: OTHER
First posted: 2018-12-31
Enrollment: 48
Sex: MALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The investigators assigned subjects to two training groups and collected pre - and post-test data
Primary purpose: BASIC_SCIENCE

Brief summary: To investigate whether and how the CBM training will alleviate the symptoms of addiction in Internet gaming disorders.

Detailed description: The purpose of this study is to use the modification training of cognitive bias to ameliorate the severity and symptoms of Internet gaming disorders(IGD); the neural mechanisms of cognitive bias modification and its effect during cued-induced craving task in subjects with IGD will be investigated as well. This project will be conducted in Beijing, China.

Eligibility criteria: Inclusion Criteria:

1, DSM-5 recommended diagnosis of Internet gaming disorder :

1. the scores of the 9 items of DSM-5 recommended diagnosis for Internet gaming disorder ≥ 5.
2. engagement in popular Internet games (e.g. Arena of Valor, League of Legends and Player Unknown's Battle Grounds) for over 20 hours per week for a minimum of 12 months.

2, the scores of the Y-IAT(Young-Internet addiction Test) ≥ 50

Exclusion Criteria:

current or history of use of illegal substances and gambling;

current or history of psychiatric or neurological illness;

current use of psychotropic medications.

Primary outcomes:
measure: Behavioral outcome
timeFrame: 60- 80 minutes after training
measure: Resting-state functional connectivity alterations in brain.
timeFrame: 30-45 minutes after training
measure: task-based fMRI brain activation
timeFrame: 45-60 minutes after training
measure: Correlation analysis
timeFrame: 30- 60 minutes after training
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University
state: Beijing
Study officials:
affiliation: Beijing Normal University
name: Jin-Tao Zhang, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Wiers CE, Stelzel C, Gladwin TE, Park SQ, Pawelczack S, Gawron CK, Stuke H, Heinz A, Wiers RW, Rinck M, Lindenmeyer J, Walter H, Bermpohl F. Effects of cognitive bias modification training on neural alcohol cue reactivity in alcohol dependence. Am J Psychiatry. 2015 Apr;172(4):335-43. doi: 10.1176/appi.ajp.2014.13111495. Epub 2014 Dec 19.
citation: Wiers CE, Ludwig VU, Gladwin TE, Park SQ, Heinz A, Wiers RW, Rinck M, Lindenmeyer J, Walter H, Bermpohl F. Effects of cognitive bias modification training on neural signatures of alcohol approach tendencies in male alcohol-dependent patients. Addict Biol. 2015 Sep;20(5):990-9. doi: 10.1111/adb.12221. Epub 2015 Jan 13.
citation: Rinck M, Becker ES. Approach and avoidance in fear of spiders. J Behav Ther Exp Psychiatry. 2007 Jun;38(2):105-20. doi: 10.1016/j.jbtep.2006.10.001. Epub 2006 Nov 28.