Clinical trial NCT04909320: Mobile-based Positive Psychological Support for Smoking Cessation Via "Quit to Win" Contest 2021 (QTW 2021)
Official title: Building Capacity and Promoting Smoking Cessation in the Community Via "Quit to Win" Contest 2021: Mobile-based Positive Psychological Support on Smoking Cessation
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Smoking Cessation
Keywords: smoking cessation
positive psychological support
mobile health
peer supporter
Lead sponsor: The University of Hong Kong
Sponsor class: OTHER
Collaborators: name: Hong Kong Council on Smoking and Health
First posted: 2021-06-01
Enrollment: 1094
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This study aims to explore the effectiveness of a combined intervention using brief cessation advice and personalized chat-based positive psychological support compared with the control group on current smokers who join the Quit to Win Contest.

Detailed description: Smoking is a leading cause of many diseases and deaths globally. Although Hong Kong has a relatively low overall smoking rate of 10.2% (in 2019), health and economic burdens due to smoking are still substantial. The practice of smoking might predispose smokers to COVID-19 infection and poor prognosis. Growing evidence has also suggested that smokers are at higher risk of developing serious respiratory and cardiovascular symptoms in the COVID-19 pandemic than non-smokers. Smoking cessation in the post-COVID-19 era is the key priority to meet the HKSAR Government's target of reducing smoking prevalence to 7.8% by 2025.

Mental health problems are commonly comorbid with smoking and related problems. Our population-based survey amidst the COVID-19 pandemic found current smokers were at higher risk of suffering from anxious symptoms (adjusted OR 1.84 95% CI 1.27, 2.67), depressive symptoms (adjusted OR 2.04 95% CI 1.40, 2.96), and stress symptoms (adjusted β 0.54 95% CI 0.26, 0.82) compared with non-smokers. We also observed mental health burden increased during the COVID-19 pandemic with approximately doubling of the prevalence of anxious symptoms (15.8 vs. 9.3) and depressive symptoms (14.8 vs. 6.3) compared with the pre-COVID-19 pandemic (2017). Mental health can be both precursors and consequences of smoking. Previous studies have suggested that depressive symptoms and low positive affect during and after SC attempts are associated with poor cessation outcomes. This implies that a combined intervention of behavioral and psychological SC intervention is needed, particularly under the circumstance of worsening mental health problems.

Therefore, our study aims to test the effectiveness of a combined intervention using brief cessation advice and personalized chat-based positive psychological support compared with the control group on current smokers who join the Quit to Win Contest.

Eligibility criteria: Inclusion Criteria:

* Hong Kong residents aged 18 or above
* Smoke at least 1 tobacco stick (includes HTP) per day or use e-cigarette daily in the past 3-month
* Able to communicate in Chinese
* Saliva cotinine 30 ng/ml or above
* Intent to quit/reduce smoking
* Able to use the instant messaging tool (e.g., WhatsApp, WeChat) for communication

Exclusion Criteria:

* Smokers who have communication barrier (either physically or cognitively)
* Smokers who are currently participating in other SC programmes or services

Primary outcomes:
measure: Biochemically validated abstinence
timeFrame: 6-month follow-up
Secondary outcomes:
measure: Biochemically validated abstinence
timeFrame: 3-month follow-up
measure: Self-reported 7-day point prevalence quit rate
timeFrame: 3-month follow-up
measure: Self-reported 7-day point prevalence quit rate
timeFrame: 6-month follow-up
measure: Self-reported reduction
timeFrame: 3-month follow-up
measure: Self-reported reduction
timeFrame: 6-month follow-up
measure: Self-reported depressive symptoms
timeFrame: 3-month follow-up
measure: Self-reported depressive symptoms
timeFrame: 6-month follow-up
measure: Self-reported anxious symptoms
timeFrame: 6-month follow-up
measure: Self-reported anxious symptoms
timeFrame: 3-month follow-up
measure: Self-reported use of smoking cessation service
timeFrame: 3-month follow-up
measure: Self-reported use of smoking cessation service
timeFrame: 6-month follow-up
measure: Self-rated health
timeFrame: 3-month follow-up
measure: Self-rated health
timeFrame: 6-month follow-up
measure: Self-reported happiness
timeFrame: 3-month follow-up
measure: Self-reported happiness
timeFrame: 6-month follow-up
measure: Self-reported quit attempts
timeFrame: 3-month follow-up
measure: Self-reported quit attempts
timeFrame: 6-month follow-up
measure: Self-reported resilience
timeFrame: 3-month follow-up
measure: Self-reported resilience
timeFrame: 6-month follow-up
measure: Self-reported optimistic
timeFrame: 3-month follow-up
measure: Self-reported optimistic
timeFrame: 6-month follow-up
measure: Self-reported loneliness
timeFrame: 3-month follow-up
measure: Self-reported loneliness
timeFrame: 6-month follow-up
measure: Self-reported stress
timeFrame: 6-month follow-up
measure: Self-reported stress
timeFrame: 3-month follow-up
measure: Self-reported social support
timeFrame: 3-month follow-up
measure: Self-reported social support
timeFrame: 6-month follow-up
measure: Self-reported positive affect
timeFrame: 3-month follow-up
measure: Self-reported positive affect
timeFrame: 6-month follow-up
measure: Self-reported negative affect
timeFrame: 6-month follow-up
measure: Self-reported negative affect
timeFrame: 3-month follow-up
Other outcomes:
Locations:
city: Hong Kong
country: China
facility: Hong Kong Council on Smoking and Health (COSH)
state: Hong Kong
Study officials:
affiliation: The University of Hong Kong
name: Man Ping Wang, PhD
role: PRINCIPAL_INVESTIGATOR
References: