Clinical trial NCT05936892: Comparative Effects of UE Aerobic and Resistance Training on Cardiorespiratory Fitness in Hypertensive Patients
Official title: Comparative Effects of UE Aerobic and Resistance Training on Cardiorespiratory Fitness in Hypertensive Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Blood Pressure
Keywords: Cardiorespiratory Fitness
Oxygen Consumption
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-07-10
Enrollment: 40
Sex: ALL
Minimum age (years): 35
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: simple random sampling into group A \& group B to collect data. Group A will be given upper extremity aerobic training and group B will be given upper extremity resistance training. The study will be completed within the time duration of ten months. Primary Outcome measures of the research will be pain, range of motion, and quality of life.

Detailed description: A randomized clinical trial will be conducted at Multan institute of cardiology, Multan. Non probability convenient sampling technique will be applied on--patients who will be allocated through simple random sampling into group A \& group B to collect data. Group A will be given upper extremity aerobic training and group B will be given upper extremity resistance training. The study will be completed within the time duration of ten months. Primary Outcome measures of the research will be pain, range of motion, and quality of life. Data will be analyzed using SPSS software version 25. After assessing normality of data by Shapiro-wilk test, it will be decided either parametric or non-parametric test will be used within a group or between two groups.

Eligibility criteria: Inclusion Criteria:

* Age group of 35-65years
* Both male and females
* Patients with blood pressure \>140/90mm Hg

Exclusion Criteria:

* Regular engagement in physical exercise training in past 4 weeks
* Patients with secondary hypertension
* Patients using more than one hypertensive drugs
* Recent myocardial infarction
* Congestive heart failure
* Uncontrolled cardiac arrythmia

Primary outcomes:
measure: 6 MWT RESISTANCE TRAINING ON CARDIORESPIRATORY FITNESS IN HYPERTENSIVE PATIENTS
timeFrame: 4 weeks
Secondary outcomes:
measure: Borg rating of perceived exertion (RPE)
timeFrame: 4 weeks
Other outcomes:
Locations:
city: Multān
country: Pakistan
facility: Multan Institute of Cardiology, Multan
state: Punjab
Study officials:
affiliation: Riphah International University
name: Sidra Faisal, MS.CPPT
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Franco OH, Peeters A, Bonneux L, de Laet C. Blood pressure in adulthood and life expectancy with cardiovascular disease in men and women: life course analysis. Hypertension. 2005 Aug;46(2):280-6. doi: 10.1161/01.HYP.0000173433.67426.9b. Epub 2005 Jun 27.
citation: Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I; ESC Scientific Document Group. 2018 ESC/ESH Guidelines for the management of arterial hypertension. Eur Heart J. 2018 Sep 1;39(33):3021-3104. doi: 10.1093/eurheartj/ehy339. No abstract available.
citation: Smart TFF, Doleman B, Hatt J, Paul M, Toft S, Lund JN, Phillips BE. The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis. Age Ageing. 2022 Jun 1;51(6):afac143. doi: 10.1093/ageing/afac143.
citation: Mandsager K, Harb S, Cremer P, Phelan D, Nissen SE, Jaber W. Association of Cardiorespiratory Fitness With Long-term Mortality Among Adults Undergoing Exercise Treadmill Testing. JAMA Netw Open. 2018 Oct 5;1(6):e183605. doi: 10.1001/jamanetworkopen.2018.3605.
citation: Khalid Z, Farheen H, Tariq MI, Amjad I. Effectiveness of resistance interval training versus aerobic interval training on peak oxygen uptake in patients with myocardial infarction. J Pak Med Assoc. 2019 Aug;69(8):1194-1198.