Clinical trial NCT05874076: Physiotherapy in Mutated COVID-19 Patients
Official title: The Effects of Mutation on Short Term Physiotherapy Success in Hospitalized COVID-19 Patients: a Prospective Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: COVID-19 Pandemic
Lead sponsor: Giresun University
Sponsor class: OTHER
First posted: 2023-05-24
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The prospective study was conducted at a single location within the COVID-19 department of a city hospital. The study included COVID-19 patients who were hospitalized in the COVID-19 service and consulted for physiotherapy, were between the ages of 18 and 65, and had the capacity and inclination to participate in one daily physiotherapy session five days per week.

Detailed description: A hospital's COVID-19 service recruited 32 participants for the study. Patients were divided into two groups: COVID-19 (n=16; age = 53.81 9.48) and mutation (n=16; age = 55.25 10.12). Both groups underwent physiotherapy consisting of mobilization, normal range of motion, and a respiratory exercise program (COVID-19 group: 9.945.85 days; mutation group: 7.632.83 days). Every patient participated in a once-daily physiotherapy program. The patients' muscle strength, mobility, daily activities, exercise capacity, and perception of fatigue were assessed. To compare groups, the mixed repeated measures ANOVA model was used.

Eligibility criteria: Inclusion Criteria:

Patients with COVID-19 who were hospitalized in the COVID-19 service Patients were consulted for physiotherapy Patients with the capacity and willingness to participate in one daily physiotherapy session five days a week

Exclusion Criteria:

* Patients who had an exercise contraindication, were uncooperative, had multi-organ failure, had an acute infection, or were PEG-fed were excluded.

Primary outcomes:
measure: muscle strength
timeFrame: an average of 9 days
Secondary outcomes:
measure: mobility assessment
timeFrame: an average of 9 days
measure: Exercise capacity
timeFrame: an average of 9 days
Other outcomes:
Locations:
city: Giresun
country: Turkey
facility: Giresun University
state: Gi̇resun
city: Giresun
country: Turkey
facility: Giresun University
Study officials:
affiliation: Giresun University
name: ULKU K SAHIN, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Lemhofer C, Gutenbrunner C, Schiller J, Loudovici-Krug D, Best N, Bokel A, Sturm C. Assessment of rehabilitation needs in patients after COVID-19: Development of the COVID-19-rehabilitation needs survey. J Rehabil Med. 2021 Apr 27;53(4):jrm00183. doi: 10.2340/16501977-2818.
citation: Brower RG. Consequences of bed rest. Crit Care Med. 2009 Oct;37(10 Suppl):S422-8. doi: 10.1097/CCM.0b013e3181b6e30a.
citation: Piquet V, Luczak C, Seiler F, Monaury J, Martini A, Ward AB, Gracies JM, Motavasseli D; Covid Rehabilitation Study Group. Do Patients With COVID-19 Benefit from Rehabilitation? Functional Outcomes of the First 100 Patients in a COVID-19 Rehabilitation Unit. Arch Phys Med Rehabil. 2021 Jun;102(6):1067-1074. doi: 10.1016/j.apmr.2021.01.069. Epub 2021 Feb 4.