Clinical trial NCT06610955: Comparison of Two Different Intensity Exercises on Young Women With Obesity
Official title: Effects of High Intensity Interval Training vs. Moderate Intensity Continuous Training on Fat Loss,Serum Adiponectin,Leptin,Omentin Level,Sleep and Quality of Life in Young Females With Obesity
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Obesity
Exercise Training
Keywords: Obesity
Exercise Training
Adipokines
Lead sponsor: Ahi Evran University Education and Research Hospital
Sponsor class: OTHER
Collaborators: name: Kirsehir Ahi Evran Universitesi
First posted: 2024-09-24
Enrollment: 40
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Two groups without control group
Primary purpose: TREATMENT

Brief summary: Obesity is one of the most common preventable public health problems. Diet regulation and exercise practices are the most commonly used methods in reducing fat tissue. There are various exercise methods applied in the weight loss process and the effects of different types of exercise modalities on body fat rate and metabolic status.The aim of our study is to determine the effects of high intensity interval exercise and moderate intensity continuous exercise on serum , omentin, leptin and adiponectin levels, anthropometric measurements used in obesity follow up, body fat percentage and their effects on the quality of sleep and life of women with obesity.

Detailed description: Female participants aged 18-45 with a body mass index of 30-40 kg/m² who met the inclusion and exclusion criteria were randomized into two groups using a simple randomization method using a computer. One group will perform high intensity interval exercise with an Ergoline bicycle ergometry device for 45 minutes a day, 5 days a week for 8 weeks, while the other group will perform moderate intensity continuous exercise on the same device. Peripheral venous blood samples will be taken from all participants at the beginning and end of the study, anthropometric measurements used in obesity monitoring of all participants will be taken and noted, and participants will be asked to fill out questionnaires containing questions about their sleep and quality of life. The analysis of the blood samples taken will be carried out in the Biochemistry Laboratory of Kırşehir Ahi Evran University. The data of our study will be analyzed with the statistical package program SPSS version 23.0.

Eligibility criteria: Inclusion Criteria:

* Female between the age of 18-45
* BMI 30-40 kg/m²
* Primary obesity

Exclusion Criteria:

* Patients with cardiac, pulmonary, endocrinological, rheumatological diseases
* Pregnancy and breastfeeding
* Using antipsychotics, antidepressants (lithium, tricyclic antidepressants, mono amino oxidase inhibitors), anticonvulsants, antihistamines, glucocorticoids, antidiabetics (sulfonylureas, insulins, glitazones) sex hormones
* Using oral contraceptives
* History of bariatric surgery
* Patients using obesity medication in the last 6 months, complying with a regular diet and exercise program
* Presence of orthopedic or neurological problems that difficulty of participate aerobic exercise training

Primary outcomes:
measure: Serum adipokine levels
timeFrame: 8 weeks
Secondary outcomes:
measure: Anthropometric measurement
timeFrame: 8 weeks
measure: Percentage of body fat
timeFrame: 8 weeks
measure: The impact of weight on quality of life
timeFrame: 8 weeks
measure: Quality of sleep
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Kırşehir
country: Turkey
facility: Kırşehir Ahi Evran Üniversitesi
Study officials:
affiliation: Ahi Evran Univeristy
name: Figen Tuncay, Professor
role: PRINCIPAL_INVESTIGATOR
affiliation: Kirsehir Ahi Evran Universitesi
name: Elif Kapaklı, RA
role: STUDY_CHAIR
affiliation: Kirsehir Ahi Evran Universitesi
name: Gamze Turna Saltoğlu, Ass. Prof.
role: STUDY_CHAIR
affiliation: Kirsehir Ahi Evran Universitesi
name: Başak Çiğdem Karaçay, Assoc. Prof.
role: STUDY_CHAIR
affiliation: Kirsehir Ahi Evran Universitesi
name: Nazife Kapan, Ass. Prof.
role: STUDY_CHAIR
affiliation: Kirsehir Ahi Evran Universitesi
name: Başak Kavalcı Kol, Ass. Prof.
role: STUDY_CHAIR
affiliation: Kirsehir Ahi Evran Universitesi
name: Merve Fırat, Ass. Prof.
role: STUDY_CHAIR
References: