Clinical trial NCT06658327: Comparative Effects Of Dynamic And Static Stretching In Postmenopausal Females With Knee Osteoarthritis
Official title: Comparative Effects Of Dynamic And Static Stretching On Pain, Lower Extremity Function And Knee Range Of Motion In Postmenopausal Females With Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Postmenopausal
Knee Osteoarthritis
Keywords: Pain
Postmenopausal
knee Osteoarthritis
Dynamic Stretching
Static Stretching
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-10-26
Enrollment: 58
Sex: FEMALE
Minimum age (years): 50
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: As the aging population continues to grow, there is a pressing need to explore effective interventions to alleviate the symptoms of osteoarthritis, particularly in postmenopausal women who may experience unique challenges. Osteoarthritis (OA) is progressive joint disease characterized by joint inflammation and a reparative bone response and is one of the top five most disabling conditions that affects more than one-third of persons \>65 years of age, commonly affecting hands, feet, spine, hips, and knees. Among the various therapeutic modalities, stretching exercises, both dynamic and static, have gained attention for their potential to enhance joint flexibility, reduce pain, and improve functional outcomes.

Detailed description: The study will be a randomized clinical trial and will be conducted in Jinnah Hospital, Mafaza-Tul-Hayat Hospital Lahore and Mayo Hospital Lahore. This study will be completed in time duration of 7 months after the approval of synopsis. Non-probability convenience sampling technique will be used and 58 participants will be recruited in study after randomization. The subjects will be divided into two groups. Group A will receive dynamic stretching of hamstrings and quadriceps with static stretching and Group B will receive dynamic stretching without static stretching after warm up as baseline treatment. The tools that will be used are Osteoarthritis outcome scale Goniometer Lower extremity function scale, Strength, MMT, NPRS, after data collection data will be analyzed by using SPSS version 21

Eligibility criteria: Inclusion Criteria:

* Age 50 to 65
* Diagnosed patients of OA with grade 3
* Multiparous (5 children)
* Fertile females
* Pain greater than 6 on NPRS

Exclusion Criteria:

* BMI \> 30
* Early menarche ≤10 or 11 years.
* Cancer i.e breast cancer ,Ovrian cancer
* Any bone deformity before menopause i.e limb length discrepancy, angulation

Primary outcomes:
measure: GONIOMETER
timeFrame: 6 Weeks
measure: LOWER EXTREMITY FUNCTION SCALE
timeFrame: 6 Weeks
measure: STRENGTH MMT
timeFrame: 6 Weeks
measure: Numerical Pain Rating Scale
timeFrame: 6 Weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Mafaza-Tul-Hayat Hospital
state: Punjab
Study officials:
affiliation: Ripah International university, Lahore
name: Tanzeela Majeed, MS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Heidari B. Knee osteoarthritis prevalence, risk factors, pathogenesis and features: Part I. Caspian J Intern Med. 2011 Spring;2(2):205-12.
citation: Jung JH, Bang CH, Song GG, Kim C, Kim JH, Choi SJ. Knee osteoarthritis and menopausal hormone therapy in postmenopausal women: a nationwide cross-sectional study. Menopause. 2018 Dec 21;26(6):598-602. doi: 10.1097/GME.0000000000001280.