Clinical trial NCT06127082: Left Cardiac Chambers Size in Obese Individuals and Its Relation to BMI and Waist Circumference
Official title: Left Cardiac Chambers Size in Obese Individuals and Its Relation to BMI and Waist
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Obesity
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2023-11-13
Enrollment: 200
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: - 1-Patient age 18 years old or above. 2-Patient BMI 30kg/m2 or higher . 3-Patient waist circumference in men 102cm or more and in women 88cm or more. 4-Obese patient with comorbidities (e.g DM,HTN).

Brief summary: Aim of study:

To determine if there is relation between left cardiac chambers size ,BMI and waist circumference in obese individuals.

1. Primary outcomes:

   -To determine if there is relation between left cardiac chambers size ,BMI and waist circumference in obese individuals.
2. Secondary outcomes:

   * To determine the effect of obesity on heart health in obese individuals.

Detailed description: Body mass index and waist circumference are important measurements of our bodies as they can affect our health.The person is obese if he has BMI equal 30 or higher.Increased risk of obesity related disease occurs in men with waist circumference equal 102 cm or more and woman with waist circumference equals 88 cm or more. increasing BMI and waist circumference can increase risk of type 2 diabetes mellitus ,hypertension ,cardiovascular disease and cerebrovascular accidents.There are many diseases that can affect left cardiac chambers size like aortic, mitral valvediseases,hypertension and atherosclerosis.Screening of patients heart by echocardiography allow us to detect changes in the muscle of heart and this allow doctors to put treatment plan to patient to prevent heart health from deterioration. In this study the investigators want to know if there an association between left cardiac chambers size ,BMI and waist circumference in obese individuals.

Eligibility criteria: Inclusion Criteria:

* 1-Patient age 18 years old or above. 2-Patient BMI 30kg/m2 or higher . 3-Patient waist circumference in men 102cm or more and in women 88cm or more. 4-Obese patient with comorbidities (e.g DM,HTN).

Exclusion Criteria:

* 1-Patient age 18 years old. 2-Patient BMI less than 30 kg/m2. 3-Patient waist circumference in men less than 102cm and in women less than 88cm.

Primary outcomes:
measure: To determine if there is correlation between left cardiac chambers size in mm ,BMI in kg/m^2 and waist circumference in cm in obese individuals
timeFrame: Baseline
Secondary outcomes:
measure: To determine the effect of obesity on heart health in obese individuals.
timeFrame: Baseline
Other outcomes:
Locations:
Study officials:
affiliation: Assiut University
name: Walaa Anwar, professor
role: STUDY_DIRECTOR
References:
citation: Moukarzel J, Guevara E, Casciaro ME, Guilenea FN, Pascaner AF, Craiem D. Echocardiographic Measurements of Left Heart Chamber Size in a Large Cohort of Subjects: Comparison of Body Surface Area and Height Indexing to Account for Effects of Obesity. J Am Soc Echocardiogr. 2022 Nov;35(11):1159-1167.e2. doi: 10.1016/j.echo.2022.08.001. Epub 2022 Aug 8.