Clinical trial NCT05491876: Active Cycle Of Breathing Technique Verses Breathing Exercises In Post ICU COVID-19 Patients
Official title: Comparison Of Active Cycle Of Breathing Technique And Breathing Exercises On Oxygen Saturation And Pulmonary Function Test In Post ICU COVID-19 Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Post Covid-19 Patients
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-08-08
Enrollment: 48
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: The study came to the conclusion that both techniques, breathing exercises with and without ACBT were beneficial in raising PaO2, FEV1, FVC, and the FEV1/FVC ratio as well as oxygen saturation.

However, based on their mean differences, ACBT with breathing exercises was more beneficial in terms of the indicated end measures.
Primary purpose: TREATMENT

Brief summary: The experiment was randomized and controlled. To create groups A and B,48 individuals were selected by sample selection criteria. Evaluation of oxygen saturation and pulmonary function tests were taken using a pulse oximeter and spirometer. Group A got chest physiotherapy with breathing exercises and ACBT whereas Group B got chest physiotherapy with breathing exercises. The treatment took 15-30 minutes and consisted of one session per day, treatment was given 6 days a week for up to 2 weeks and examined by using SPSS 22.

Detailed description: The experiment was randomized and controlled. To create groups A and B,48 individuals were selected by sample selection criteria. Evaluation of oxygen saturation and pulmonary function tests were taken using a pulse oximeter and spirometer. Group A got chest physiotherapy with breathing exercises and ACBT whereas Group B got chest physiotherapy with breathing exercises. The treatment took 15-30 minutes and consisted of one session per day, treatment was given 6 days a week for up to 2 weeks and examined by using SPSS 22.

Eligibility criteria: Inclusion Criteria:

* Adult population

  * Age limit 18 -50
  * All patients positive with confirmed COVID-19 by polymerase chain reaction (PCR) test and chest computed tomography scan (CT-scan)

Exclusion Criteria:

* The patient cannot take part in the trial if they have any kind of muscular-skeletal issue.

  * COVID-19-related intubation history
  * A clear clinical mental or cognitive disability of any kind.
  * Patient on ventilator

Primary outcomes:
measure: SPIROMETRY
timeFrame: 4 weeks
measure: PULSE OXIMETRY
timeFrame: 4 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Jinnah Hospital Lahore
state: Punjab
Study officials:
affiliation: Riphah International University
name: Sidra Faisal, MS.CPPT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Gastaldi AC, Paredi P, Talwar A, Meah S, Barnes PJ, Usmani OS. Oscillating Positive Expiratory Pressure on Respiratory Resistance in Chronic Obstructive Pulmonary Disease With a Small Amount of Secretion: A Randomized Clinical Trial. Medicine (Baltimore). 2015 Oct;94(42):e1845. doi: 10.1097/MD.0000000000001845.
citation: van Mourik Y, Rutten FH, Bertens LCM, Cramer MJM, Lammers JJ, Gohar A, Reitsma JB, Moons KGM, Hoes AW. Clinical research study implementation of case-finding strategies for heart failure and chronic obstructive pulmonary disease in the elderly with reduced exercise tolerance or dyspnea: A cluster randomized trial. Am Heart J. 2020 Feb;220:73-81. doi: 10.1016/j.ahj.2019.08.021. Epub 2019 Sep 1.
citation: Gephine S, Mucci P, Grosbois JM, Maltais F, Saey D. Physical Frailty in COPD Patients with Chronic Respiratory Failure. Int J Chron Obstruct Pulmon Dis. 2021 May 17;16:1381-1392. doi: 10.2147/COPD.S295885. eCollection 2021.