Clinical trial NCT03589638: Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics
Official title: Effects of C-MAC Videolaryngoscope, McGRATH Videolaryngoscope and Macintosh Direct Laryngoscope on Intraocular Pressure and Hemodynamics; a Randomized, Double-blind Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anesthesiology Devices Associated With Adverse Incidents
Intraocular Pressure
Keywords: tracheal intubation
videolaryngoscopy
hemodynamics
intraocular pressure
Lead sponsor: Inonu University
Sponsor class: OTHER
First posted: 2018-07-18
Enrollment: 3
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Prospective, Randomized, double blind Clinical Trial
Primary purpose: TREATMENT

Brief summary: In this study, participants aimed to compare the effects of direct laryngoscopic endotracheal intubation and videolaryngoscopic intubation with C-MAC videolaryngoscope and McGrath videolaryngoscope on intraocular pressure and hemodynamics.

Detailed description: The maintenance of airway opened is one of the main responsibility of the anesthetist. Intubation procedure during anesthesia application benefits such as airway opening, airway and breathing control, aspiration hazard, respiratory effort and dead space reduction, surgical comfort and airway control during resuscitation. Laryngoscopy and tracheal intubation increases in heart rate, blood pressure and the intraocular pressure. The sympathetic-adrenal activity caused by the stimulation of the laryngeal and tracheal tissues is responsible for these negative effects. Endotracheal intubation with videolaryngoscopy is an alternative method used in airway management. Laryngoscopy and tracheal intubation under general anesthesia and laryngeal mask and airway control techniques cause different hemodynamic and catecholamine levels.

Eligibility criteria: Inclusion Criteria:

* American Society of Anesthesiologist Score 1-2
* Mallampati 1 ve 2

Exclusion Criteria:

* Glaucoma,
* Diabetes mellitus
* Cardiovascular and pulmonary disease
* American Society of Anesthesiologist Score III-IV
* Bdoy mass index greater than 35
* Difficult intubation history
* Obstetric surgery
* Propofol, fentanyl, rocuronium contraindication

Primary outcomes:
measure: intraocular pressure
timeFrame: From beginning of Anesthesia to 10th minute of surgery
Secondary outcomes:
measure: mean arterial pressure
timeFrame: From beginning of Anesthesia to 10th minute of surgery
measure: systolic arterial pressure
timeFrame: From beginning of Anesthesia to 10th minute of surgery
measure: diastolic arterial pressure
timeFrame: From beginning of Anesthesia to 10th minute of surgery
measure: heart rate
timeFrame: From beginning of Anesthesia to 10th minute of surgery
measure: peripheral oxygen saturation
timeFrame: From beginning of Anesthesia to 10th minute of surgery
Other outcomes:
Locations:
city: Malatya
country: Turkey
facility: Inonu University Medical Faculty
Study officials:
affiliation: İnönü Üniversitesi Tıp Fakültesi
name: Ahmet Selim Ozkan, MD
role: PRINCIPAL_INVESTIGATOR
References: