Clinical trial NCT02788838: The Impact of Food Advertisements on Brain Response and Eating Behavior in Children
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pediatric Obesity
Keywords: Magnetic Resonance Imaging
Energy Intake
Commercials
Children
Lead sponsor: Penn State University
Sponsor class: OTHER
First posted: 2016-06-02
Enrollment: 88
Sex: ALL
Minimum age (years): 7
Maximum age (years): 9
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: Children ages 7-9 years old

Brief summary: The purpose of this project is to examine the impact that television food advertisements have on brain responses and eating behavior in children. Food advertisements enhance children's liking and intake of foods that tend to be high in energy content and low in nutritional value. Although several studies have measured the differences in children's food intake after watching advertisements, none have shown the brain mechanisms associated with this change in behavior. In order to clarify the relationship between food advertising and eating behavior, the investigators have assembled a team with expertise in functional imaging, eating behaviors, and clinical pediatric research. First, the investigators will observe the differences in children's eating behaviors after being exposed to food commercials or non-food commercials. Second, the investigators will measure the difference in child brain response to high and low energy foods after being exposed to food commercials or non-food commercials. These data will allow us to identify which areas of the brain are specifically affected by exposure to food commercials and correlate activity in these areas with children's measured food intake in the laboratory. Children ages 7-9 will participate in this 5-visit study which will be completed over the course of 12 months. Understanding how food advertisements impact children's brain responses and subsequent eating behaviors will have implications for understanding why some children respond differently to these cues than others. These outcomes may also inform the development of more effective programs and policies to prevent childhood obesity.


Eligibility criteria: Inclusion Criteria:

* Right-handed
* English as native language
* Reading at/above grade level
* Not Claustrophobic
* Generally Healthy

Exclusion Criteria:

* Left-handedness
* Metal in or on body that cannot be removed
* Claustrophobic
* Medication usage that may alter brain activity or blood flow
* Medical disorder that may impact comfort or safety in MRI scanner
* Food allergies

Primary outcomes:
measure: Functional magnetic resonance imaging (fMRI), blood oxygen level dependent (BOLD) response to high and low energy foods following food commercial priming
timeFrame: Collected at fMRI scan at week 4 or 5 (randomized)
measure: Functional magnetic resonance imaging, blood oxygen level dependent (BOLD) response to high and low energy foods following toy commercial priming
timeFrame: Collected at fMRI scan at week 4 or 5 (randomized)
measure: Baseline Energy Intake
timeFrame: Collected at week 1 of the study
measure: Energy Intake following food commercials
timeFrame: Collected at week 2 or 3 (randomized) of the study
measure: Energy Intake following toy commercials
timeFrame: Collected at week 2 or 3 (randomized) of the study
Secondary outcomes:
measure: Region of Interest (ROI)-response to food type by condition
timeFrame: Collected at fMRI scans at weeks 4 and 5 of study
Other outcomes:
measure: Appetitive traits
timeFrame: Collected at week 1
measure: Television and Internet use and exposure
timeFrame: Collected at week 1
measure: BMI-z score
timeFrame: Collected at week 1
measure: Liking and Wanting of Foods
timeFrame: Collected at week 1
measure: Pubertal Development
timeFrame: Collected at week 1
measure: Parental feeding strategies
timeFrame: Collected at week 1
measure: Height
timeFrame: Collected at week 1
measure: Weight
timeFrame: Collected at week 1
measure: Body Fat Percentage
timeFrame: Collected at week 1
measure: BMI
timeFrame: Collected at week 1
Locations:
city: University Park
country: United States
facility: The Pennsylvania State University
state: Pennsylvania
Study officials:
References: