Clinical trial NCT02012127: Description of Sign-and-symptom Associations at Acromegaly Diagnosis.
Official title: Description of Sign-and-symptom Associations at Acromegaly Diagnosis.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Acromegaly
Lead sponsor: Ipsen
Sponsor class: INDUSTRY
First posted: 2013-12-16
Enrollment: 648
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Acromegalic patients

Brief summary: The purpose of this study is to describe most characteristic association of signs and symptoms present at the time of acromegaly diagnosis.


Eligibility criteria: Inclusion Criteria:

* Adult patient (greater than or equal to 18 years old)
* Patient with acromegaly, diagnosed for less than 5 years

Exclusion Criteria:

* Patient who have objected to the collection of his/her data

Primary outcomes:
measure: Description of the most characteristic sign-and-symptom associations of acromegaly, collected by a patient questionnaire.
timeFrame: At the time of patient diagnosis, up to 3 months
Secondary outcomes:
measure: Description of demographic and clinical characteristics of patients with acromegaly, collected by a patient questionnaire.
timeFrame: At the time of patient diagnosis, up to 3 months
Other outcomes:
Locations:
city: Amiens
country: France
facility: Hôpital Sud
city: Besançon
country: France
facility: CHU Besançon Hôpital Jean Minjoz
city: Brest
country: France
facility: Hôpital la Cavale Blanche
city: Caen
country: France
facility: Chu Cote de Nacre
city: Creteil
country: France
facility: Hôpital Henri Mondor
city: Grenoble
country: France
facility: Chu de Grenoble Hôpital Albert Michallon
city: Lille
country: France
facility: Hôpital Claude Huriez
city: Limoges
country: France
facility: Hôpital le Cluzeau
city: Lyon
country: France
facility: Hôpital Neuro-cardiologique
city: Marseille
country: France
facility: Hôpital de la Timone
city: Montpellier
country: France
facility: Hôpital Lepeyronie
city: Nancy
country: France
facility: Hôpitaux de Brabois
city: Orléans
country: France
facility: CHR Orléans - Hôpital la Source
city: Paris
country: France
facility: CH de Bicetre
city: Paris
country: France
facility: CH Pitie Salpetreire
city: Paris
country: France
facility: Hôpital Lariboisiere
city: Pessac
country: France
facility: Hôpital Haut Leveque
city: Reims
country: France
facility: CHU Reims - Hôpital Robert Debre
city: Rennes
country: France
facility: Hôpital Sud Anne de Bretagne
city: Rouen
country: France
facility: CHU Rouen - Hôpital de Bois Guillaume
city: Saint Etienne
country: France
facility: Hôptital Nord
city: Strasbourg
country: France
facility: Hôpital Civil
city: Strasbourg
country: France
facility: Hôpital de Hautepierre
city: Toulouse
country: France
facility: Hôpital Larrey
city: Tours
country: France
facility: CHU Bretonneau
Study officials:
affiliation: Ipsen
name: Ipsen Medical Director
role: STUDY_DIRECTOR
References:
citation: Caron P, Brue T, Raverot G, Tabarin A, Cailleux A, Delemer B, Renoult PP, Houchard A, Elaraki F, Chanson P. Signs and symptoms of acromegaly at diagnosis: the physician's and the patient's perspectives in the ACRO-POLIS study. Endocrine. 2019 Jan;63(1):120-129. doi: 10.1007/s12020-018-1764-4. Epub 2018 Sep 29.