Clinical trial NCT04941495: Effects of Cervical Proprioceptive Training in CMNP
Official title: Effects of Proprioceptive Training in the Management of Chronic Mechanical Neck Pain.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Neck Pain
Keywords: chronin non traumatic neck pain
Joint position error
Cervical Proprioception
NDI
Lead sponsor: Aqua Medical Services (Pvt) Ltd
Sponsor class: INDUSTRY
First posted: 2021-06-28
Enrollment: 44
Sex: ALL
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Random allocation will be done through toss coin method into two groups; Conventional Physiotherapy Control group (n=22) and Proprioceptive training Experimental group (n=22).
Primary purpose: TREATMENT

Brief summary: It is a randomized control trial will be conducted at Federal Government Polyclinic hospital on 44 chronic mechanical neck pain patients. Patients will be recruited in the study through non probability purposive sampling. Random allocation will be done through toss coin method into two groups; Conventional Physiotherapy Control group (n=22) and Proprioceptive training Experimental group (n=22). Research data will be collected through structural questionnaires. Tools will be used to collect data are NPRS, NDI, Goniometer (Cervical ROMs) and proprioception.

Detailed description: Neck pain is a very common complaint. In the general population and musculoskeletal practice, it occurs second to low back pain in its frequency. Neck pain has a point prevalence of nearly 13% and lifetime prevalence of nearly 50%. Neck pain and disability are prevalent throughout the industrialized society. It is a common reason for visits in accidents and emergency departments. In Chiropractic treatment, Neck pain is the second most common complaint. It Is the result of fast, mechanical, stressful life, lack of mobility and poor posture. Some injury can also lead to neck pain. Sometimes neck pain lasts for a few days and itself goes away, but when it persists for a long time it results in greater problems. Neck pain is said to be more common in females than in males and in peaks at the middle age. Sedentary lifestyles are contributing to the prevalence of neck pain. Neck pain is one of the most debilitating musculoskeletal problems. Neck problems are a significant source of disability to patients, but they have not been studied in detail as low back pain problems.

Neck pain can be categorized in many ways i.e. Duration(Acute, Sub acute, Chronic), Intensity, Severity, Type(Mechanical, Neuropathic etc.). Among them duration proves to be the best predictor of outcome. Short duration pain have better prognosis than long standing pain. Mechanical Neck Pain is defined as widespread cervical and/or shoulder pain possessing mechanical properties, such as symptoms aggravated by prolonged or abnormal neck posture, neck mobility and/or by palpation of the neck musculature Mechanical pain originates from the spine or by its supporting structures, such as muscles and ligaments. Pain arising from the facet joints eg, arthritis, diskogenic pain, and myofascial pain can be named as Mechanical pain. It is proposed to be associated with several anatomic structures, predominantly facet joints and uncovertebral(Luschka's joints). The risk factors for mechanical neck pain include abnormal posture, stress, substantial lifting and anxiety. Around 15% females and 10% males suffer from Chronic mechanical neck pain at any one time in life. Clinicians find it challenging to prevent a patient from entering into the chronic phase of their condition.

The most mobile part of the vertebral column is the upper cervical spine. And it is at the expense of its mechanical stability. Neuromuscular control to the mobile cervical spine is provided by the highly developed proprioceptive system. Neck pain can lead to disturbed afferent input from the cervical region that may be a possible cause of symptoms such as dizziness, unsteadiness, and visual disturbances. Signs of altered postural stability, cervical proprioception, and head and eye movement control are also said to be the cause of disturbed afferent input.

By an abundance of mechanoreceptors, the proprioceptive system of the cervical spine is very well developed especially from the muscle spindles in the deep segmental upper cervical muscles. Muscle spindle afferent are more important because they are the first ones to operate in proprioception. As compared to the lower cervical spine, the upper cervical spine has an abundance of muscle spindle receptors and greater contributions to reflex activity and connections to the visual and vestibular systems. It concludes that patients with the cause of upper cervical complaints in neck pain have a greater chance for balance and visual disturbances than those with complaints of lower cervical spine.

The ability to maintain body orientation and posture in relation to the surrounding environment is a key process required for normal functions such as coordinated movements. Sensorimotor control of stable upright posture and head and eye movement depends on afferent information from the vestibular, visual and proprioceptive systems, which all together merge in several areas of the Central Nervous System. Proprioception is important for well-adapted sensorimotor control. Proprioception fulfills roles in feedback sensorimotor control and regulation of muscle stiffness, being specifically important for movement acuity, joint stability, coordination, and balance. For head-eye co-ordination and movement control, cervical proprioception is uniquely important. Musculoskeletal disorders due to pain, effusion, trauma, and fatigue alter the normal proprioceptive mechanism.

Neck pain patients are said to have a poor awareness of their head and neck posture, and a few patients are reported to complain about "whopping head" which might be the cause of altered cervical position sense. The rehabilitation procedures in the field of musculoskeletal diseases aim to improve muscular force, joint mobility, and proprioceptive sensibility. Currently, only strength and mobility are evaluated in cervical spine rehabilitation programs, although a wealth of cephalic and neck receptors suggests a major emphasis on proprioceptive information in postural and dynamic functions of the head-neck system.

A study by J Arami and colleagues (2014) on the "Applicability of proprioceptive and endurance measurement protocols to treat patient with chronic non-specific neck pain" was conducted. Chronic neck pain patients were divided into two groups, one of them received endurance training and the other group received proprioceptive training. This study suggested that endurance exercise was a more efficient method for improving endurance and Proprioceptive training was better in resolving joint position error and Pain. Both protocol appeared to be useful in treating patients with chronic non specific neck pain.

Cervicogenic headache is getting common in young adults along with proprioception deficit in the cervical region. In this study, 30 participants of Cervicogenic headache were included. The control group received stretching exercises. The experimental group in addition to stretching received cervical stabilization exercises. Headache disability index and neck proprioception were evaluated before and after the treatment programs. At the end of 4rth week, Headache disability index scores and neck pain and proprioception error improved more in the experimental group. Hence the study concluded that Cervical stabilization exercises along with stretching are more effective in improving neck proprioception and Headache disability index than stretching alone.

The presence of strong coupling between gaze orientation and muscle neck activity has been well documented in humans. This co-ordination between neck motor functions and eye strongly suggest that eye head coupling based rehabilitation program are more appropriate to improve neck proprioception and this afterwards aid in reducing pain. A comparison was done between two groups of neck pain patients one of them receiving the traditional physiotherapy protocol for chronic neck pain and the experimental group received an eye head coupling based rehabilitation program modified from Revel et al., in addition to the traditional protocol given to the other group. The results showed a significant reduction in scores of Neck Pain and Disability scale in both groups with a greater decrease in the experimental subjects.

Eligibility criteria: Inclusion Criteria:

1. Mechanical neck pain of Chronic duration (Symptoms present form more than 3 months)
2. Limitation of cervical ROM
3. Age 18-55
4. Men and Women

Exclusion Criteria:

1. Sharp purser test positive
2. Vertebral artery insufficiency test positive Neck pain due to:
3. Inflammatory conditions - infections, ankylosing spondylitis, juvenile arthritis, rheumatoid arthritis and polymyalgia rheumatica.
4. Metabolic - osteoporosis, osteomalacia, Paget's disease, gout.
5. Neoplastic - metastases, myeloma, intrathecal tumours.
6. Referred pain as a result of - angina pectoris, aortic aneurysm, pancoast tumour, diaphragmatic pathology, pharyngial pathology
7. Neck injury due to trauma

Primary outcomes:
measure: Numeric Pain Rating Scale (NPRS)
timeFrame: 2 weeks
measure: Neck Disability Index
timeFrame: 2 weeks
measure: Range of Motion
timeFrame: 2 weeks
measure: Cervical Proprioception
timeFrame: 2 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Federal Government Polyclinic Hospital, Islamabad.
state: Capital
Study officials:
affiliation: Riphah International University
name: Iqra Raja, MS-OMPT
role: PRINCIPAL_INVESTIGATOR
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