Clinical trial NCT04943510: Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Soccer Game
Official title: Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Different Modality of Training in Soccer Players
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE2
Conditions: Neuromuscular Fatigue
Exercise
Keywords: Hamstring
Neuromuscular fatigue
Soccer
Performance
Lead sponsor: University Hospital, Strasbourg, France
Sponsor class: OTHER
First posted: 2021-06-29
Enrollment: 15
Sex: MALE
Minimum age (years): 16
Maximum age (years): 40
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: three randomizations will be used to determine the order of the tests that will be proposed to the subjects:

* on the one hand for the exercise modalities (match, anaerobic, aerobic)
* and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linear
Primary purpose: BASIC_SCIENCE

Brief summary: This is a monocentric study comparing hamstring and quadriceps neuromuscular fatigue after simulated soccer game, anaerobic and aerobic training sessions. The purpose of this study was:

1. To quantify the decrease of isometric force immediately after a simulate soccer game.
2. To characterize peripheral and central fatigue between hamstring and quadriceps muscles and described the kinetics of recovery after specific tasks of soccer training.
3. To compare the level neuromuscular fatigue induced by anaerobic and aerobic training.
4. To highlight correlation between neuromuscular fatigue and performance markers.


Eligibility criteria: Inclusion Criteria:

* male
* age limits: minimum: 16 ; maximum: 40 years old
* to be a soccer player, licensed to the French Football Federation
* affiliation to the social health insurance scheme
* signing an informed consent form

Exclusion Criteria:

* impossibility to give the subject enlightened information (subject in emergency situation, difficulties in understanding the study, ...)
* subject under the protection of justice
* subject under guardianship or curatorship
* lower limbs musculotendinous or articular problems
* smoker or having been a smoker in the last 5 years
* subject wearing a pacemaker
* drug treatment in progress and impossibility to stop it within 7 days before the beginning of the study.

Primary outcomes:
measure: Difference in maximal isometric hamstring strength before and immediately after exercise (i.e., pre vs. immediate post exercise) expressed as a percentage (%).
timeFrame: Before and immediately post exercise (i.e., during the first minute after cessation of exercise)
Secondary outcomes:
measure: Relative difference (in %) in maximum isometric hamstring strength before and after exercise (i.e., pre- vs. post-exercise), relative to pre-exercise strength across different test types.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Relative difference (in %) in maximal isometric quadriceps strength before and after exercise (i.e., pre vs. post exercise), related to preexercise strength according to the different types of tests.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Relative difference (%) in maximum isometric hamstring and quadriceps strength for each test type at the different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) hamstring potentiated jerk amplitude (N) relative to pre-exercise amplitude by event type at different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) potentiated jerk amplitude (N) of the quadriceps, relative to pre-exercise amplitude, by test type at different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Difference in amplitude of the potentiated jerk (N) before and after exercise, related to the preexercise amplitude according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Difference in the level of voluntary hamstring activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Difference in the level of voluntary quadriceps activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Difference in the level of voluntary action before and after exercise, related to the level of action before exercise, according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Differences in overall fatigue, peripheral fatigue, and central fatigue of hamstrings versus quadriceps between exercise modalities.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
measure: Ratio (%) of initial to post-exercise values based on field indicators and neuromuscular fatigue.
timeFrame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Other outcomes:
Locations:
city: Strasbourg
country: France
facility: Hopitaux Universitaires de Strasbourg
Study officials:
References: