Clinical trial NCT02609672: Resilience for Older Workers With OA Through Exercise
Official title: Resilience and Longevity for Older Workers With Arthritis Through Exercise
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoarthritis, Knee
Osteoarthritis, Hip
Keywords: Exercise
Resilience
Lead sponsor: McMaster University
Sponsor class: OTHER
First posted: 2015-11-20
Enrollment: 24
Sex: ALL
Minimum age (years): 45
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Exercise is effective at reducing pain while improving physical function. However we do not know if exercise can boost resilience in the workplace, to allow people with osteoarthritis to work as long as they desire. Previous research shows that exercise holds the most promise for helping people enjoy their work because it reduces sick time, reduces pain, and improves productivity. However, little work has examined the effect of exercise for people with arthritis in the workplace. The purpose of the study is to investigate whether exercise improves resilience in the workplace, mobility, fitness, strength, and pain in comparison to no exercise in those with knee and/or hip osteoarthritis.

Detailed description: The Canadian workforce is aging. The most prevalent age group is 50-54 years and most of these Canadians will aim to continue working over the next 10 years. However, the impact of arthritis on aging Canadians compromises their ability to continue working. By 2031, over 2 million Canadians aged 45 to 64 years will have arthritis. We aim to boost the ability of older adults with the most common arthritis, osteoarthritis (OA), to engage in the workforce for as long as they desire. Identifying strategies to promote productivity among older workers with knee and hip OA will be of great public health significance in the coming decades. However, we face two challenges. First, obesity among sedentary workers is a risk for worsening knee and hip OA. Second, large occupational loads on the knee and hip worsen OA. Exercise has the most promise in addressing these challenges because it reduces pain and sick time, and improves mental health. Thus, there is a call for studies examining exercise for the aging worker with knee and hip OA. The purpose of this study is to examine the impact of an OA-specific leg strengthening exercise program, delivered within the workplace, on mobility, pain, physical capacity, and resilience among older workers with knee or hip OA.

Eligibility criteria: Inclusion Criteria:

* 45 years of age or older
* McMaster employee
* Sedentary job (stand or walk for \<1/3 of work day)
* Able to safely climb two flights of stairs
* Hip pain
* Hip pain during internal rotation and hip flexion
* Knee pain
* Less than 30 minutes of morning stiffness in the knee
* Crepitus in the knee with active range of motion
* Bony enlargement around the knee
* Bony tenderness to palpation at the knee
* No warmth around the knee

Exclusion Criteria:

* Any other forms of arthritis
* Osteoporosis-related fracture
* History of patellofemoral symptoms
* Active non-arthritic hip or knee disease
* Hip or knee surgery
* Use of cane or walking aid
* Unstable heart condition
* Neurological conditions
* Hip, knee or ankle injuries in past 3 months
* Physician-advised restriction to physical activity
* Any injuries that would prohibit participation in exercise
* Ipsilateral ankle conditions
* Currently receiving cancer treatment
* Currently pregnant

Primary outcomes:
measure: Change in Lower Extremity Function
timeFrame: Week 1 and Week 13
Secondary outcomes:
measure: Change in Self-reported Knee and Hip Pain
timeFrame: Week 1 and Week 13
measure: Change in Resilience
timeFrame: Week 1 and Week 13
measure: Change in Mobility Performance (Six-Minute Walk Test)
timeFrame: Week 1 and Week 13
measure: Change in Mobility Performance (40 Metre Walk Test)
timeFrame: Week 1 and Week 13
measure: Change in Mobility Performance (Stair Ascent)
timeFrame: Week 1 and Week 13
measure: Change in Mobility Performance (Stair Descent)
timeFrame: Week 1 and Week 13
measure: Change in Mobility Performance (30-second Chair Stand Test)
timeFrame: Week 1 and Week 13
measure: Change in Mobility Performance (Timed Up and Go Test)
timeFrame: Week 1 and Week 13
measure: Change in Arthritis-related Self-efficacy
timeFrame: Week 1 and Week 13
measure: Change in Depression Status
timeFrame: Week 1 and Week 13
measure: Change in Grip Strength (Absolute)
timeFrame: Week 1 and Week 13
measure: Change in Grip Strength (Relative)
timeFrame: Week 1 and Week 13
measure: Change in Isometric Knee and Hip Extensor and Flexor Strength
timeFrame: Week 1 and Week 13
measure: Change in Cardiovascular Fitness
timeFrame: Week 1 and Week 13
Other outcomes:
Locations:
city: Hamilton
country: Canada
facility: McMaster University
state: Ontario
Study officials:
affiliation: McMaster University
name: Monica R Maly, PT, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Chopp-Hurley JN, Brenneman EC, Wiebenga EG, Bulbrook B, Keir PJ, Maly MR. Randomized Controlled Trial Investigating the Role of Exercise in the Workplace to Improve Work Ability, Performance, and Patient-Reported Symptoms Among Older Workers With Osteoarthritis. J Occup Environ Med. 2017 Jun;59(6):550-556. doi: 10.1097/JOM.0000000000001020.