Clinical trial NCT06460376: Comparative Effects of Wurn Technique and Mercier Therapy in Women With Endometriosis
Official title: Comparative Effects of Wurn Technique and Mercier Therapy on Dyspareunia, Dysmenorrhea, and Quality of Life in Women With Endometriosis
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Endometriosis
Keywords: Dyspareunia
Dysmenorrhea
endometriosis
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-06-14
Enrollment: 26
Sex: FEMALE
Minimum age (years): 25
Maximum age (years): 43
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This project was a Randomized controlled trial conducted to check the comparative effects of wurn technique and mercier therapy on dyspareunia, dysmenorrhea, and quality of life in women with endometriosis. The duration was 6 months, convenient sampling was done, subjects following eligibility criteria from DHQ Hospital Narowal and THQ Hospital Shakargarh were randomly assigned, a baseline assessment was done, Group A participants were given baseline treatment along with wurn technique 2 sessions per week for 6 weeks, Group B participants were given baseline treatment along with mercier therapy 1 session per week for 6 weeks, the post-intervention assessment was done, via the Marinoff Scale, Mankoski Pain Scale and Endometriosis Health Profile Questionnaire (EHP 30). Data was analyzed by using SPSS version 26.

Detailed Description: Endometriosis

Detailed description: Endometriosis is the condition involving the presence of glands or stroma of the endometrial lining outside the uterus cavity. Its characteristics include unpleasant pain in the pelvic region, impaired fertility, pain during or after sex, and heavy bleeding during periods. Endometriosis occurs as a result of genetic, angiogenic, immunological, and inflammatory factors. In endometriosis, adhesions may be formed due to local inflammation. It can also occur as the blood-filled implants start bleeding in their surroundings. As a result of this bleeding healing occurs which causes scar formation. Pharmacologically, NSAIDS are used for instant pain relief. The most common surgical approach is laparoscopy. Physiotherapy in its various forms can be an excellent complement to the gynecological treatment of endometriosis. as previous studies also reported the effect of pelvic massage, pelvic manipulation, kinesiotherapy, and hydrotherapy. According to researcher knowledge, there is limited evidence on wurn technique and mercier therapy and how these techniques improve dyspareunia, dysmenorrhea, and quality of life in women with endometriosis. This study aims to see the comparative effects of wurn technique and mercier therapy on dyspareunia, dysmenorrhea, and quality of life in women with endometriosis.

Eligibility criteria: Inclusion Criteria:

* Age ranging from 25-43(17)
* Diagnosed patients with endometriosis
* BMI (18.5-29.9),(normal and overweight)
* Multigravida
* Mode of delivery: vaginal delivery or c section both
* Females having grade 1 or 2 grade on the dyspareunia scale
* Females having moderate scores on EHP -30

Exclusion Criteria:

* Malignancy
* Pregnancy
* Fibroids
* Pelvic congestion syndrome
* Pelvic inflammatory disease
* Females having IUD (inter uterine device)
* Recent abdominal or pelvic surgery
* Ovarian abscess

Primary outcomes:
measure: Endometriosis Health Profile Questionnaire (EHP 30)
timeFrame: 6 Weeks
Secondary outcomes:
measure: Mankoski Pain Scale
timeFrame: 6 weeks
Other outcomes:
measure: Marinoff Scale
timeFrame: 6 weeks
Locations:
city: Narowal
country: Pakistan
facility: DHQ Hospital Narowal
state: Punjab
city: Shakargarh
country: Pakistan
facility: THQ Hospital Shakargarh
state: Punjab
Study officials:
affiliation: Riphah International University
name: Hafiza Neelam
role: PRINCIPAL_INVESTIGATOR
References:
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citation: Christ JP, Yu O, Schulze-Rath R, Grafton J, Hansen K, Reed SD. Incidence, prevalence, and trends in endometriosis diagnosis: a United States population-based study from 2006 to 2015. Am J Obstet Gynecol. 2021 Nov;225(5):500.e1-500.e9. doi: 10.1016/j.ajog.2021.06.067. Epub 2021 Jun 17.