Clinical trial NCT05778682: Decannulation of Tracheostomy Cannula Based on Suctioning Frequency and High-flow Oxygen Protocol in the Intensive Care Unit
Official title: Decannulation of Tracheostomy Cannula Based on Suctioning Frequency and High-flow Oxygen Protocol in the Intensive Care Unit
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Tracheostomy Weaning
Lead sponsor: Université de Sherbrooke
Sponsor class: OTHER
First posted: 2023-03-21
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: In the DECAP-ICU trial, the investigators will be focusing on the impact of a new weaning tracheostomy technique based on suctioning frequency compared to the standard practice of capping tolerance.


Eligibility criteria: Inclusion Criteria:

* Weaning from mechanical ventilation for at least 24 hours
* Randomisation must be done in 24 hours of the mechanical ventilation weaning.

Exclusion Criteria:

* Sabadell \> 2
* Contraindication of decannulation : Glasgow Coma Scale \<6, severe dysphagia, non permeable respiratory tracks, neuromuscular disease (expect for the ICU weakness) and long term tracheostomy.

Primary outcomes:
measure: Time to decannulation
timeFrame: Frome date of randomisation to the date of the actual decannulation or to the date of death, whichever comes first, assessed up to 48 months.
Secondary outcomes:
measure: Time to decannulation criteria
timeFrame: From date of randomisation to the date when the criteria of decannulation are met or to the date of death, whichever comes first, assessed up to 48 months.
measure: Length of stay ICU
timeFrame: From admission to the date when the patient quit the ICU, through study completion, average of 6 to 12 months.
measure: Length of stay hospital
timeFrame: From admission to the date when the patient is discharge of the hospital, through study completion, average of 6 to 12 months.
measure: ICU readmission
timeFrame: Through study completion, average of 6 to 12 months.
measure: Decannulation failure
timeFrame: Through study completion, average of 6 to 12 months.
measure: Mechanical Ventilation weaning failure
timeFrame: Through study completion, average of 6 to 12 months.
measure: Adverses effects
timeFrame: Through study completion, average of 6 to 12 months.
measure: Mortality
timeFrame: Through study completion, average of 6 to 12 months.
Other outcomes:
Locations:
city: Sherbrooke
country: Canada
facility: Université de Sherbrooke
state: Quebec
Study officials:
References:
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