Clinical trial NCT04062292: Gait Parameters and Balance in Patients With Obstructive Lung Diseases
Official title: Investigation of Gait Parameters and Balance in Patients With Obstructive Lung Diseases
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Gait Disorder, Sensorimotor
Keywords: balance
chronic obstructive diseases
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2019-08-20
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The obstructive lung diseases from every subgroups: COPD, asthma and bronchiectasis patients

Brief summary: In the literature, most of the studies examining the gait characteristics and balance separately or examining the relationship between them are on patients with COPD.

No study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma was found.A convincing link between gait disturbances and falls in COPD patients is still unknown and further research is needed. Therefore, the purpose of our study; gait parameters and balance in individuals with obstructive pulmonary disease. We will also examine the relationship between gait parameters and extrapulmonary clinical indicators of these individuals.

Detailed description: Patients with COPD call walking as one of the most problematic activities in daily life. Patients with COPD walk less in daily life than their healthy peers. Gait characteristics of extrapulmonary comorbidities that probably affect the musculoskeletal and cardiovascular system vary. The gait assessment gives an idea about the biomechanical factors associated with a reduction in walking distance in COPD patients. In patients with COPD, after the onset of shortness of breath or leg fatigue, a decrease in cadence during walking, shortened stride length, an increase in the time spent in the double support period, an increase in the peak ankle dorsi flexion moment is observed. During gait, there is an increase in balance disorders in the mediolateral direction. In addition, patients with COPD walk on a constant speed treadmill with more stride time and less step width variability. Studies have shown that patients with COPD have increased temporal walking characteristics, decreased step and stride length, and increased walking variability.

In the literature, most of the studies that examine gait characteristics and balance separately or examine the relationship between them are on patients with COPD. No study examining gait parameters in other obstructive pulmonary patients such as bronchiectasis and asthma has been found. A persuasive link between walking disorders and falls in COPD patients is still unknown and further research is needed. This study will contribute to clarifying the mechanisms of why the balance studied in patients with COPD is adversely affected.

Eligibility criteria: Inclusion Criteria for Obstructive Lung Diseases

1. Being diagnosed with obstructive lung disease,
2. Have not experienced acute exacerbation or infection in the last 1 week,
3. To be between 18-65 years,
4. Volunteering for research,
5. To be able to walk and cooperate.

Exclusion Criteria for Obstructive Lung Diseases:

1. Use walking aid or be chronic oxygen support
2. To have orthopedic or neuromuscular comorbidities that may affect walking patterns.
3. Having had lung cancer, sarcoidosis, tuberculosis disease or lung surgery.

Inclusion Criteria for Healthy People 1.18-65 years of age, 2. Volunteer to participate in the research, 3. To be able to walk and cooperate.

Exclusion Criteria for Healthy People

1. Having any cardiopulmonary disease,
2. To have an advanced orthopedic disease that may affect functional capacity measurement and gait patterns.

Primary outcomes:
measure: Gait parameters
timeFrame: 01.09.2020-08.07.2021
Secondary outcomes:
measure: Functional Balance and Fall Risk
timeFrame: 01.09.2020-08.07.2021
measure: Functional Exercise Capacity
timeFrame: 01.09.2020-08.07.2021
measure: Respiratory Muscle Strength
timeFrame: 01.09.2020-08.07.2021
measure: Peripheral Muscle Strength
timeFrame: 01.09.2020-08.07.2021
measure: Cognitive Status
timeFrame: 01.09.2020-08.07.2021
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Naciye Vardar-Yagli
Study officials:
affiliation: Hacettepe University
name: Naciye Vardar-Yagli, PhD
role: PRINCIPAL_INVESTIGATOR
References: