Clinical trial NCT06457308: Compare the Agility Exercise and Resistance Exercise on Physical Function and Stability in Osteoporotic Women
Official title: Tainan Hospital, Ministry of Health and Welfare, Taiwan
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Postmenopausal Osteoporosis
Agility Exercise
Physical Function
Balance Stability
Fall Prevention
Keywords: postmenopausal osteoporosis
agility exercise
physical function
multi-component exercise
fall prevention
Lead sponsor: Tainan Hospital, Ministry of Health and Welfare
Sponsor class: OTHER
First posted: 2024-06-13
Enrollment: 51
Sex: FEMALE
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Non-randomized, quasi-experimental design.
Primary purpose: PREVENTION

Brief summary: Osteoporosis weakens bones with age, increasing fracture risk. Exercise improves physical function and reduces falls, crucial for preventing osteoporotic fractures, especially with balance, resistance, and multi-component training. Agility exercise, integrating various aspects like aerobic, strength, balance, and cognitive tasks, is promising for fall prevention in older adults, though its effectiveness in osteoporosis is not extensively studied.

This study compares agility and resistance exercise impacts on physical function and balance stability in postmenopausal osteoporosis. Fifty-one women (average age: 68±6.3y, BMI: 22.3±2.7 kg/m2) were divided into agility exercise (AG), resistance exercise (RG), and control groups (CG) through purposive sampling. AG and RG received added intervention training once a week for 2 hours over 12 weeks. Main outcomes included physical function and balance stability measured through various tests.

Detailed description: Main activities of agility training group (AG): Use rope ladders and cones to perform multiple tasks of direction changes, acceleration and deceleration of footsteps, hand and foot coordination and spatial orientation training.

Main activities of resistance training group (AG): Resistance training for upper and lower limb muscles and core muscles, including squats, use of elastic bands, and simple bars.

Eligibility criteria: Inclusion Criteria:

* women with osteoporosis( diagnosed with DXA, T-score≦-2.5 in L-spine or hip)
* postmenopausal, more than 50 years old,

Exclusion Criteria:

* unable to attend the training sessions due to physical problems
* had joined previous exercise program

Primary outcomes:
measure: Physical function of upper limb strength
timeFrame: after the completed training course, about 12 weeks
measure: Physical function of upper limbs strength
timeFrame: after the completed training course, about 12 weeks
measure: Physical function of lower limbs
timeFrame: after the completed training course, about 12 weeks
measure: Physical function of dynamic balance
timeFrame: after the completed training course, about 12 weeks
measure: Physical function of lower limbs
timeFrame: after the completed training course, about 12 weeks
measure: Physical function of static balance
timeFrame: after the completed training course, about 12 weeks
measure: Stability index
timeFrame: after the completed training course, about 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Tainan
country: Taiwan
facility: Chen, Ying-Chen
Study officials:
References:
citation: Donath L, van Dieen J, Faude O. Exercise-Based Fall Prevention in the Elderly: What About Agility? Sports Med. 2016 Feb;46(2):143-9. doi: 10.1007/s40279-015-0389-5.
citation: Lichtenstein E, Morat M, Roth R, Donath L, Faude O. Agility-based exercise training compared to traditional strength and balance training in older adults: a pilot randomized trial. PeerJ. 2020 Apr 14;8:e8781. doi: 10.7717/peerj.8781. eCollection 2020.
citation: Morat M, Morat T, Zijlstra W, Donath L. Effects of multimodal agility-like exercise training compared to inactive controls and alternative training on physical performance in older adults: a systematic review and meta-analysis. Eur Rev Aging Phys Act. 2021 Feb 25;18(1):4. doi: 10.1186/s11556-021-00256-y.
citation: Miko I, Szerb I, Szerb A, Bender T, Poor G. Effect of a balance-training programme on postural balance, aerobic capacity and frequency of falls in women with osteoporosis: A randomized controlled trial. J Rehabil Med. 2018 Jun 15;50(6):542-547. doi: 10.2340/16501977-2349.