Clinical trial NCT05821127: Effect of Neurodynamic Exercises and Education Program Applied With Virtual Reality Assisted Telerehabilitation Method in Conservative Treatment of Carpal Tunnel Syndrome
Official title: The Effect of Neurodynamic Exercises and Education Program Applied With Virtual Reality Assisted Telerehabilitation Method in Conservative Treatment of Carpal Tunnel Syndrome: A Single-Blind Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Carpal Tunnel Syndrome
Peripheral Neuropathy
Median Nerve Entrapment
Keywords: Carpal Tunnel Syndrome
Virtual Reality
Telerehabilitation
Exercise
Education
Ergonomics
Lead sponsor: Istanbul University
Sponsor class: OTHER
First posted: 2023-04-20
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: A random number table containing numbers from 1 to 60 was created for 2 groups through the computer program. Participants were numbered in order of application. Participants were assigned to groups to which their numbers belonged in the table of random numbers.
Primary purpose: TREATMENT

Brief summary: The aim in this prospective, randomized and controlled, single-blind study; In the conservative treatment of patients diagnosed with carpal tunnel syndrome, to investigate the effects of neurodynamic exercises that applied with nonimmersive virtual reality technology and patient education program presented by the telerehabilitation method on pain-numbness, functional status and quality of life, to compare the effects of neurodynamic exercises that applied with traditional methods and standard education given to patients in outpatient clinic conditions on the same parameters.


Eligibility criteria: Inclusion Criteria:

* 18-65 years
* Being diagnosed with CTS clinically and electrophysiologically

Exclusion Criteria:

* \<18 years or \>65 years
* Distal motor latency \> 6.0 msn.
* Thenar atrophy
* Surgery history for CTS
* Steroid injection for CTS
* Physical treatment for CTS in the last 6 months
* Cervical radiculopathy
* Tenosynovitis
* Peripheral polyneuropathy
* Another compressive neuropathy in the ipsilateral upper extremity
* History of trauma/fracture to the hand-wrist region
* Pregnancy
* Metabolic disease
* Rheumatic/autoimmune disease
* Kidney failure
* Lack of internet access
* Not having the equipment to make video calls at home

Primary outcomes:
measure: Change in Boston Carpal Tunnel Syndrome Questionnaire (BCTSQ)
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Visual Pain Scale (VAS)
timeFrame: baseline, eight week of intervention, sixteen week of intervention
Secondary outcomes:
measure: Change in Brief International Classification of Functioning (ICF) Core Set for Hand Conditions Questionnaire
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Short Form-36 (SF-36) Questionnaire
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Semmes Weinstein Monofilament Test (SWMT)
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Two Point Discrimination Test (TPDT)
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Hand Grip Force
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Thumb and Forefinger Pinch Force
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Manuel Muscle Testing of M. Abductor Pollicis Brevis
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Vibration Sensation
timeFrame: baseline, eight week of intervention, sixteen week of intervention
measure: Change in Nerve Conduction Study (NCS)
timeFrame: baseline, eight week of intervention, sixteen week of intervention
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation
Study officials:
affiliation: Istanbul University
name: Baran Sezgin, MD
role: PRINCIPAL_INVESTIGATOR
References: