Clinical trial NCT02463214: Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients
Official title: Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Transplantation Infection
Lead sponsor: University of British Columbia
Sponsor class: OTHER
Collaborators: name: Vancouver Coastal Health Research Institute
First posted: 2015-06-04
Enrollment: 45
Sex: ALL
Minimum age (years): 19
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: This study involves sampling bone marrow transplant patients, hospital workers and the patient room for microbes using swabs and other techniques. We send these samples to the laboratory, where they will use state-of-the art technology to identify and relate the microbes to each other. This study also involves putting copper, nickel, or titanium into some hospital rooms, and seeing whether these metals influences the growth of microbes. Some equipment in the hospital room, such as faucets and soap dispensers will be replaced by sensor-based (e.g. touchless) controls.

Detailed description: Bacteria and other microbes are everywhere, the majority of which are harmless. They live on our bodies, on everyday objects, in food, and in our environment. They are passed around through the many interactions with other people and our surroundings. Some are even beneficial, helping us digest our food or protecting us from infections caused by harmful microbes.

In rare instances, some of the harmful microbes can cause infections. When a microbe causes an infection while we are in healthcare facilities, they are called "Healthcare-associated infections", or "HAIs". Examples that you may have heard of include Clostridium difficile, and MRSA (methicillin-resistant Staphylococcus aureus). Vancouver General Hospital already has some of the lowest HAI rates in the country. We have dedicated hospital workers that do a great job at preventing HAIs, but we are always looking for ways to be even better.

Eligibility criteria: Inclusion Criteria (Patients):

* undergoing allogenic bone marrow transplant for acute myeloid leukemia
* will be admitted to the leukemia and bone marrow transplant service at Vancouver General Hospital
* admission to the ward anticipated to be approximately 28 days

Exclusion Criteria (Patients):

* allergies to copper, nickel or titanium
* patients admitted for stays anticipated to be less than 28 days

Inclusion Criteria (Health care worker):

* undergoing allogenic bone marrow transplant for acute myeloid leukemia
* caring for patient enrolled in the study as a primary nurse

Exclusion Criteria (Health care worker):

* allergies to copper, nickel or titanium

Primary outcomes:
measure: Change in bioburden on surfaces
timeFrame: up to 28 days
Secondary outcomes:
Other outcomes:
Locations:
city: Vancouver
country: Canada
facility: Vancouver General Hospital
state: British Columbia
Study officials:
affiliation: The University of British Columbia
name: Linda Hoang, MD FRCPC
role: PRINCIPAL_INVESTIGATOR
affiliation: The University of British Columbia
name: Elizabeth Bryce, MD FRCPC
role: PRINCIPAL_INVESTIGATOR
affiliation: Sidra Medicine
name: Patrick Tang, MD PhD FRCPC
role: PRINCIPAL_INVESTIGATOR
References: