Clinical trial NCT04246008: Effects of Neuromuscular Training on Functional Capacity in Acute Coronary Syndrome Patients
Official title: Effects of Neuromuscular Training on Functional Capacity in Acute Coronary Syndrome Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Acute Coronary Syndrome
Keywords: acute coronary syndrome
neuromuscular training
cardiac rehabilitation
functional capacity
Lead sponsor: Cardenal Herrera University
Sponsor class: OTHER
First posted: 2020-01-29
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: This is a mixed-design study. It includes a two-group parallel, randomized clinical trial with acute coronary syndrome patients.
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to analyse the effects of neuromuscular training on functional capacity in patients with acute coronary syndrome, compared to the classic strength training of the cardiac rehabilitation programs

Detailed description: So far, there are no previous studies that analyze the effects of neuromuscular training on functional capacity in patients with acute coronary syndrome.

Aim: The main objective of this study is to assess the effects of a 10 weeks neuromuscular training vs traditional strength training programme in patients with acute coronary syndrome.

Design: Randomized clinical trial

Eligibility criteria: Inclusion Criteria:

* Acute coronary syndrome patients
* Physical activity must have been prescribed

Exclusion Criteria:

* inflammatory cardiac disease
* severe or moderate ventricular dysfunction
* heart failure
* severe arrhytmias
* systemic hypertension \>95% percentile
* pulmonary hypertension \>40 mmHg
* aortic stenosis
* baseline O2 \<90%
* severe valve insufficiency

Primary outcomes:
measure: Incremental Shuttle Walking Test
timeFrame: 10 weeks
Secondary outcomes:
measure: Chester Step Test
timeFrame: 10 weeks
measure: 30 seconds sit-to- stand test
timeFrame: 10 weeks
measure: Changes in hip muscle strength
timeFrame: 10 weeks
measure: Cardiopulmonary exercise testing
timeFrame: 10 weeks
measure: Sexual Health Inventory for Men
timeFrame: 10 weeks
measure: EQ-5D-5L
timeFrame: 10 weeks
Other outcomes:
Locations:
city: Valencia
country: Spain
facility: Arguisuelas Martinez Maria Dolores
Study officials:
affiliation: Cardenal Herrera University
name: Maria Dolores Arguisuelas
role: PRINCIPAL_INVESTIGATOR
References:
citation: EUROASPIRE I and II Group; European Action on Secondary Prevention by Intervention to Reduce Events. Clinical reality of coronary prevention guidelines: a comparison of EUROASPIRE I and II in nine countries. EUROASPIRE I and II Group. European Action on Secondary Prevention by Intervention to Reduce Events. Lancet. 2001 Mar 31;357(9261):995-1001. doi: 10.1016/s0140-6736(00)04235-5.
citation: Skou ST, Roos EM. Good Life with osteoArthritis in Denmark (GLA:D): evidence-based education and supervised neuromuscular exercise delivered by certified physiotherapists nationwide. BMC Musculoskelet Disord. 2017 Feb 7;18(1):72. doi: 10.1186/s12891-017-1439-y.
citation: Thompson PD, Arena R, Riebe D, Pescatello LS; American College of Sports Medicine. ACSM's new preparticipation health screening recommendations from ACSM's guidelines for exercise testing and prescription, ninth edition. Curr Sports Med Rep. 2013 Jul-Aug;12(4):215-7. doi: 10.1249/JSR.0b013e31829a68cf. No abstract available.