Clinical trial NCT05929781: Turning Pattern of Different Body Segments During Turns and Turning Performance
Official title: Turning Pattern of Different Body Segments During Turns and Turning Performance in Healthy Adults and People With Parkinson's Disease
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Parkinson's Disease
Keywords: Parkinson's disease
Turning
Inter-segmental coordination
En bloc turning
Turning performance
Lead sponsor: National Yang Ming Chiao Tung University
Sponsor class: OTHER
First posted: 2023-07-03
Enrollment: 30
Sex: ALL
Minimum age (years): 20
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: 1. Young healthy adults
2. Middle to older adults
3. People with Parkinson's disease

Brief summary: This is a cross-sectional exploratory study. A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited. Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera. The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).

Detailed description: The first aim of the present study is to explore the correlation between axial segment turning pattern and turning performance in people with PD and healthy adults.

The second aim is to verify the validity and reliability of 3D motion camera in turning evaluation.

A total of 25 people with PD, 25 young healthy adults, and 25 middle to older adults will be recruited.

Axial segment turning pattern and turning performance will be evaluated in two visits using the Vicon 3D motion analysis system, Gaitup, and 3D motion camera.

The independent variables are the initiation timing of the head, upper trunk, pelvis, ankle, and foot when turning and the initiation sequence of turning (% turn). The dependent variables are turning performance, including turning velocity, turning steps, turning step length, turning step width), and stance phase (%).

For the data analysis, the Shapiro-Wilk test will be used to check for normal distribution. Pearson's correlation coefficient or Spearman's rank correlation coefficient will be used to examine the correlations between axial segment initiation timing and turning performance. To verify the validity and reliability, Pearson's correlation coefficient will be used for concurrent criterion validity. Intraclass correlation one-way random model will be used for test-retest reliability, showed with intraclass correlation coefficient and 95% confidence interval. A p-value of less than 0.05 is considered statistically significant.

Eligibility criteria: Inclusion Criteria:

* Able to walk 5 meters without assistance device
* Able to turn independently

Exclusion Criteria:

* With neurological disorders
* MMSE\< 24
* Any systemic and musculoskeletal disturbances or other causes of walking inability

Primary outcomes:
measure: Initiation timing (sec)
timeFrame: Change from baseline at one week
measure: Turning velocity (cm/sec)
timeFrame: Change from baseline at one week
measure: Turning steps
timeFrame: Change from baseline at one week
measure: Turning step length (cm)
timeFrame: Change from baseline at one week
measure: Turning step width (cm)
timeFrame: Change from baseline at one week
measure: Stance phase (%)
timeFrame: Change from baseline at one week
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
Study officials:
affiliation: Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
name: Yea-Ru Yang, Ph.D.
role: STUDY_CHAIR
References: