Clinical trial NCT06627803: Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults
Official title: Multi-Method Investigation of Social Facilitation of Alcohol Effects and Alcohol Misuse in Young Adults
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Alcohol Consumption
Alcohol Abuse/Dependence
Lead sponsor: University of Southern California
Sponsor class: OTHER
Collaborators: name: National Institute on Alcohol Abuse and Alcoholism (NIAAA)
First posted: 2024-10-04
Enrollment: 250
Sex: ALL
Minimum age (years): 21
Maximum age (years): 28
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this study is to understand social contexts and alcohol use. We hope to learn how being around peers affects alcohol consumption in young adults. About 250 young adults who drink alcohol frequently will take part in the study. This research is being funded by the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

Participation involves one in-person screening session with a same-sex platonic friend. Then participants will complete four in-person laboratory sessions where they will drink beverages containing alcohol or no alcohol. After completion of the laboratory sessions, participants will complete smartphone surveys for 28 days. Lastly, they will complete follow-up surveys 6 months and 12 months post-study enrollment.


Eligibility criteria: Inclusion Criteria:

* 21-28 years of age
* Drink regularly (1+ times/week) with a same-sex platonic friend that also meets eligibility and is willing to participate
* Regular alcohol use (3+ times/week) with at least one binge drinking episode (5+ drinks \[male\] or 4+ drinks \[female\] in about 2 hours) in the past month
* BMI of 18-30
* Own a smart device operating on the iOS or Android operating system
* Fluent in English

Exclusion Criteria:

* Pregnancy or breastfeeding or intent to get pregnant in the next 60 days (females)
* medical conditions counter-indicated for alcohol administration
* seeking treatment for alcohol use

Primary outcomes:
measure: Drug Effect Questionnaire (DEQ)
timeFrame: The DEQ will be assessed 30 minutes before alcohol administration, and again 30, 60, 90, 120, 180, and 240 minutes after alcohol administration during each session.
measure: Biphasic Alcohol Effects Scale (BAES)
timeFrame: The BAES will be assessed 30 minutes before alcohol administration, and again 30, 60, 90, 120, 180, and 240 minutes after alcohol administration during each session.
measure: Quantity of Alcohol Use during Ecological Momentary Assessment
timeFrame: Quantity of Alcohol Use will be assessed daily for 28 days.
measure: Past 30-day Alcohol Use during Follow-Up
timeFrame: Past 30-day alcohol use will be assessed 6 and 12 months after the initial laboratory sessions.
Secondary outcomes:
measure: Positive and Negative Affect Schedule (PANAS)
timeFrame: The PANAS will be assessed 30 minutes before alcohol administration, and again 30, 60, 90, 120, 180, and 240 minutes after alcohol administration during each session.
measure: Brief Young Adult Alcohol Consequences Questionnaire (YAACQ) during Ecological Momentary Assessment
timeFrame: The YAACQ will be completed daily for 28 days.
measure: Past 30-day Alcohol Consequences during Follow-Up
timeFrame: Past 30-day alcohol consequences will be assessed at 6 and 12 months following the initial laboratory sessions.
Other outcomes:
Locations:
city: Los Angeles
country: United States
facility: University of Southern California
state: California
Study officials:
References: