Clinical trial NCT04746690: Effects of Neurodynamic Mobilization and Stretching Exercises for Chronic Discogenic Sciatica
Official title: Effects of Slider, Tensioner Neurodynamic Mobilization Techniques and Stretching Exercises in Treatment of Chronic Discogenic Sciatica: A Comparative Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Physical Therapy
Lead sponsor: Cairo University
Sponsor class: OTHER
Collaborators: name: Kafrelsheikh University
First posted: 2021-02-10
Enrollment: 36
Sex: ALL
Minimum age (years): 21
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: simple random sampling
Primary purpose: TREATMENT

Brief summary: This study compares between neurodynamic mobilization and stretching exercises in treatment of chronic dicogenic sciatica

Detailed description: This study was conducted at the outpatient clinics, faculty of physical Therapy, Kafrelsheikh University to compare between the effects of slider, tensioner neurodynamic mobilization techniques and stretching exercises on pain, Range of motion (ROM) and functional disability for patients with chronic discogenic sciatica.

Design of the study:

A pre-test post-test three-armed comparative study design was used for comparison between the effects of slider, tensioner neurodynamic mobilization techniques and stretching exercises for patients with chronic discogenic sciatica.

Selection of patients:

Sample size:

Using G-power software program and regarding F test study , alpha level of 0.05, confidence interval 95% and effect size of 0.25 (to detect small effects ), three groups and 6 dependent variables, the total sample size will be 36 patient (twelve in each group).

To reach the specific sample size, forty-three patients were screened regarding the inclusion/exclusion criteria. Thirty-six patient with unilateral chronic discogenic sciatica from both sexes (....male and ... female) were recruited from the outpatient clinics, faculty of physical Therapy, Kafrelsheikh University. Their age ranged between 21-50 years.

They were randomly allocated by simple random method; to avoid selection bias, patients were asked to choose a card of three wrapped cards representing the three treatment groups:

Group (A): received Slider technique only. Group (B): received Tensioner technique only. Group (C): received Stretching exercises of back extensors, hamstrings and gastrocnemius muscles only.

Eligibility criteria: Inclusion Criteria:

1. Patients diagnosed by magnetic resonance imaging (MRI) confirming disc lesion.
2. Radicular pain for at least twelve weeks up to one year with no acute episodes for the last four weeks.
3. Positive slump test, with reproduction of neurological symptoms.
4. Ages of 21-50 years of both sexes.
5. Patients with functional disabilities e.g. during lifting or walking

Exclusion Criteria:

1. Patients with sciatica due to other pathologies e.g. lumbar canal stenosis or piriformis syndrome.
2. Patients after any spinal surgery e.g. unilateral hemilaminectomy or microdiscectomy
3. Negative slump test.
4. Progressive neurological symptoms e.g. hyperirritable and unstable symptoms.
5. History of vertebral fracture or trauma.
6. Systemic disorder e.g. diabetes mellitus.
7. Pregnant women.

Primary outcomes:
measure: Change in pain intensity measurements using visual analogue scale
timeFrame: Before treatment and after 2 weeks of treatment.
measure: Change in hip flexion range of motion measurement using universal goniometer.
timeFrame: Before treatment and after 2 weeks of treatment.
measure: Change in knee extension range of motion measurement using universal goniometer.
timeFrame: Before treatment and after 2 weeks of treatment.
measure: Change in ankle dorsiflexion range of motion measurement using universal goniometer.
timeFrame: Before treatment and after 2 weeks of treatment.
measure: Change in lumbar flexion range of motion measurement using universal goniometer.
timeFrame: Before treatment and after 2 weeks of treatment.
measure: Change in functional disability measurement using the oswestry disability index.
timeFrame: Before treatment and after 2 weeks of treatment.
Secondary outcomes:
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Haytham Ibrahim Morsi
Study officials:
affiliation: Professor of Orthopaedic Physical Therapy
name: Bassem El-nahass, Professor
role: PRINCIPAL_INVESTIGATOR
References: