Clinical trial NCT06870864: Conservative Versus Operative Management in Adhesive Intestinal Obstruction
Official title: Role of Conservative Management in Adhesive Intestinal Obstruction Versus Operative Management
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Adhesive Intestinal Obstruction
Lead sponsor: Sohag University
Sponsor class: OTHER
First posted: 2025-03-11
Enrollment: 50
Sex: ALL
Minimum age (years): 6
Maximum age (years): 70
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients with adhesive Intestinal Obstruction at Department of General Surgery, Oncological and Laparoscopic Surgeries, Sohag University Hospitals, Sohag, Egypt

Brief summary: This study aims to evaluate the role of Conservative management in patients with adhesive Intestinal Obstruction Regarding the selection criteria of the patients, duration of conservative route, success rate, and recurrence of adhesions and avoiding the surgical route complications.

Detailed description: Adhesive Intestinal Obstruction is very common and represents a serious life threatening condition, which can be caused by congenital band, following abdominal surgeries and other medical conditions like tuberculosis.

The management options for adhesive intestinal obstruction (AIO) could be operative treatment (open-laparoscopy) or non-operative (conservative management) according to many reasons.

Some reports indicate that the operative management for adhesive Intestinal obstruction lead to further adhesions in the future in addition to other possible complications (anaesthetic - iatrogenic injury during adhesolysis - wound site infections - illius-long hospital stay).

The Conservative route is recommended in all patients except those with signs of peritonitis, strangulation, or bowel ischemia which would have been diagnosed during physical examination and imaging.

A few studies compared the advantages, safety, and less complications of Conservative versus operative management. Therefore, this study will be conducted on patients with adhesive Intestinal Obstruction to compare the effectiveness of Conservative versus operative management regarding the selection criteria for the patients, the duration of the Conservative route, things to be done and what need to be observed during the conversation time.

Eligibility criteria: Inclusion Criteria:

* Age 6-70 years.
* Both sexes.
* Complete \\ Partial adhesive Intestinal Obstruction, with CT Abdomen and pelvis with oral and IV Contrast.

Exclusion Criteria:

* Patients with signs of Strangulation
* Patients with signs of peritonitis.
* Patients with signs of bowel ischemia
* Failure of Conservative management for more than 72 hours.
* Vitally unstable patients
* Patients with comorbidities which need rapid interventions.

Primary outcomes:
measure: X-Ray Changes
timeFrame: 72 Hours
measure: Passability Status
timeFrame: 72 Hours
measure: Hospital Stay Duration
timeFrame: from 3 to 5 days.
measure: Vomiting
timeFrame: 72 Hours
measure: Abdominal Signs
timeFrame: 72 Hours
Secondary outcomes:
measure: Recurrence of Attacks
timeFrame: two years previous the onset of the current attack. (During the last two years before the admission)
measure: Past Surgical History
timeFrame: two years previous the onset of the current attack. (During the last two years before the admission)
Other outcomes:
Locations:
city: Sohag
country: Egypt
facility: Faculty of Medicine, Sohag University
Study officials:
References: