Clinical trial NCT04948723: Vaccination Practices for Inflammatory Bowel Disease Patients in China With Gastroenterologists
Official title: Insufficient Awareness and Vaccination Practices for Inflammatory Bowel Disease Patients in China: A Multi-center Survey of Chinese Gastroenterologists
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Inflammatory Bowel Diseases
Keywords: inflammatory bowel diseases， vaccination
Lead sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Sponsor class: OTHER
Collaborators: name: Sixth Affiliated Hospital, Sun Yat-sen University
name: Ruijin Hospital
name: Zhujiang Hospital
name: Army Medical University, China
name: Peking Union Medical College Hospital
name: The First Affiliated Hospital of Zhejiang Chinese Medical University
name: Affiliated Hospital of Nanjing University of Chinese Medicine
name: Lishui Municipal Central Hospital, the Fifth Affiliated Hospital of Wenzhou Medical University
name: Shaoxing Shangyu People's Hospital
First posted: 2021-07-02
Enrollment: 307
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: An email with a quick response code (QRC) was sent to CCCF-affiliated gastroenterologists specializing in IBD between July 2017 and August 2017

Brief summary: The aim of the current study was to evaluate the knowledge of Chinese gastroenterologists on vaccinating patients with IBD under the assistance of Chinese Crohn's \& Colitis Foundation. The Chinese Crohn's \& Colitis Foundation (CCCF) is the first nonprofit,volunteer-driven foundation specifically for patients with IBD in China.It has been joined by IBD specialists at various hospitals in China.

Detailed description: The questionnaire contained questions regarding the respondents'information, including their gender, years in practice, clinical specialty,and source of knowledge on immunization practices. The questionnaire mainly contained three sections: knowledge of vaccinations for hepatitis A virus (HAV), HBV, and varicella; current vaccination practices for the IBD group; and reasons for not recommending these vaccinations to patients with IBD. The questionnaire composed of 13 items specifically on the three vaccinations mentioned above for immunosuppressed patients with IBD. All questions were conducted based on recognized guidelines and were reviewed by 18 IBD experts. The questionnaire captured the frequency with which the respondents assessed patients with IBD for anti-HAV/hepatitis B surface antigen (HBsAg), hepatitis B core antibody, and hepatitis B surface antibody/ anti-HAV levels, and acquired infection and immunization histories. Whether the respondents recommended these three vaccines to the IBD group before treatment was also elicited.

Eligibility criteria: Inclusion Criteria:

* gastroenterologists were members of tertiary hospitals

Exclusion Criteria:

* pediatricians were excluded, as were retired gastroenterologists and those currently in training

Primary outcomes:
measure: vaccination practices
timeFrame: between July 2017 and August 2017
Secondary outcomes:
Other outcomes:
Locations:
city: Zhejiang
country: China
facility: Shuyan Li
state: Hangzhou
Study officials:
affiliation: 2ndAffiliated Hospital, School of Medicine, Zhejiang University, China
name: Yan Chen
role: STUDY_DIRECTOR
References: