louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02458950: Characteristics and Clinical Outcomes of Anorexia Nervosa : Siriraj Hospital Experience
Official title: Characteristics and Clinical Outcomes of Anorexia Nervosa : Siriraj Hospital Experience
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Anorexia Nervosa
Keywords: Anorexia nervosa
Siriraj Hospital
Thai
Lead sponsor: Mahidol University
Sponsor class: OTHER
First posted: 2015-06-01
Enrollment: 13
Sex: ALL
Minimum age (years): 10
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients of Siriraj Hospital

Brief summary: This study is aimed to determine clinical characteristics of patients with anorexia nervosa and outcome of treatment at Sirirraj Hospital.

Detailed description: Data is derived from the medical records

Eligibility criteria: Inclusion Criteria:

* children and adolescents with newly diagnosed anorexia nervosa in Siriraj Hospiatl according to DSM IV criteria
* treated by multidisciplinary teams e.g. pediatricians specialized in nutrition and psychology and psychologist

Exclusion Criteria:

* none

Primary outcomes:
measure: types and factors contributing to outcomes of anorexia nervosa
timeFrame: one year
Secondary outcomes:
measure: Outcome of treatment of anorexia nervosa
timeFrame: one year
Other outcomes:
Locations:
city: Bangkok
country: Thailand
facility: Faculty of Medicine Siriraj Hospital, Mahidol University
Study officials:
affiliation: Mahidol University
name: Narumon Densupsoontorn, MD
role: STUDY_CHAIR
References:
citation: Nakai Y, Nin K, Noma S, Hamagaki S, Takagi R, Wonderlich SA. Outcome of eating disorders in a Japanese sample: a 4- to 9-year follow-up study. Eur Eat Disord Rev. 2014 May;22(3):206-11. doi: 10.1002/erv.2290. Epub 2014 Mar 14.
citation: Goldstein MA, Dechant EJ, Beresin EV. Eating disorders. Pediatr Rev. 2011 Dec;32(12):508-21. doi: 10.1542/pir.32-12-508. No abstract available.
Clinical trial NCT00388050: Diabetes Medication Choice
Official title: Wiser Choices for Patients With Type II Diabetes: Diabetes Medication Choice
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Type 2 Diabetes
Keywords: Decision aid, diabetes, primary care
Lead sponsor: Mayo Clinic
Sponsor class: OTHER
Collaborators: name: American Diabetes Association
First posted: 2006-10-13
Enrollment: 85
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to examine how different ways of sharing information about diabetes medication treatment options with patients can affect their choices and health.


Eligibility criteria: * Have a diagnosis of type 2 diabetes mellitus of any duration; c-peptide test not required
* Use 1 or 2 oral hypoglycemic agents; not using insulin therapy
* Are not pregnant
* Have stable but inadequate glycemic control: both A1C at the time of eligibility and previous A1c within 6 months between 7-9.5%
* Recognize their primary care provider as their main diabetes care provider
* Do not have major barriers (i.e., severe hearing impairment, dementia, cannot communicate in English) to participate in shared decision-making (per provider?s assessment)
* Have no plans to relocate out of town in the next 6 months
* Enrolment is open to males and females of diverse racial backgrounds

Primary outcomes:
measure: Understanding
timeFrame: Directly proceeding the clinical encounter
measure: Decisional Conflict
timeFrame: Directly proceeding the clinical visit
measure: Treatment Action, adherence
timeFrame: Directly proceeding the clinical encounter, 6 months after the clinical encounter
Secondary outcomes:
measure: Trust
timeFrame: Directly proceeding the clinical visit
measure: Acceptability
timeFrame: Directly proceeding the clinical encounter
Other outcomes:
Locations:
city: Rochester
country: United States
facility: Mayo Clinic
state: Minnesota
Study officials:
affiliation: Mayo Clinic
name: Victor M. Montori, M.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Wyatt KD, Branda ME, Inselman JW, Ting HH, Hess EP, Montori VM, LeBlanc A. Genders of patients and clinicians and their effect on shared decision making: a participant-level meta-analysis. BMC Med Inform Decis Mak. 2014 Sep 2;14:81. doi: 10.1186/1472-6947-14-81.
citation: LeBlanc A, Ruud KL, Branda ME, Tiedje K, Boehmer KR, Pencille LJ, Van Houten H, Matthews M, Shah ND, May CR, Yawn BP, Montori VM. The impact of decision aids to enhance shared decision making for diabetes (the DAD study): protocol of a cluster randomized trial. BMC Health Serv Res. 2012 May 28;12:130. doi: 10.1186/1472-6963-12-130.
citation: Mullan RJ, Montori VM, Shah ND, Christianson TJ, Bryant SC, Guyatt GH, Perestelo-Perez LI, Stroebel RJ, Yawn BP, Yapuncich V, Breslin MA, Pencille L, Smith SA. The diabetes mellitus medication choice decision aid: a randomized trial. Arch Intern Med. 2009 Sep 28;169(17):1560-8. doi: 10.1001/archinternmed.2009.293.
Clinical trial NCT05827250: Vibroacoustic Study of Lung Development in Newborn Infants
Official title: Passive Infrasound-to-ultrasound Vibrome Biosignatures of Lung Development in Newborn Infants
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Prematurity
Premature Birth
Premature Lungs
Prematurity; Extreme
Keywords: infrasound
vibrome
vibroacoustics
Lead sponsor: Level 42 AI, Inc.
Sponsor class: INDUSTRY
Collaborators: name: Georgetown University
First posted: 2023-04-25
Enrollment: 200
Sex: ALL
Minimum age (years): 0
Maximum age (years): 2
Standard ages: CHILD
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All infants admitted to the NICU

Brief summary: Investigators hypothesize that premature newborns with poor cardiopulmonary performance have higher morbidities and poorer physical and cognitive developmental outcomes.

Investigators further hypothesize that audible sounds combined with novel inaudible vibrations above and below human perception interpreted with transparent and auditable AI algorithms can detect and identify early gas and fluid movement anomalies not uncovered by conventional tools in an non-invasive, easy, fast, and low cost examination.

Detailed description: Worldwide preterm birth (\<37 weeks of gestation) affects approximately 10% of live births and is the leading cause of death in children less than 5 years of age. Preterm birth disrupts normal lung development leading to several respiratory complications in the neonatal period and later in life. Consequently, factors that negatively affect prenatal and early life respiratory growth can compromise the achievement of "personal-best lung function".

This novel study will generate normative, audible/inaudible frequencies, visible/invisible frequencies, and perceptible/imperceptible energies, termed vibrome biosignatures, of cardiopulmonary development and function during early postnatal development. Once baseline patterns are established, future studies will be designed to characterize vibrome biosignature differences across acute neonatal respiratory problems, such as respiratory distress syndrome, meconium aspiration, sepsis, persistent pulmonary hypertension, and congenital heart disease.

Eligibility criteria: Inclusion Criteria:

* Eligible participants include all infants admitted to the NICU.

Exclusion Criteria:

* There are no exclusions to enrollment in this study.

Primary outcomes:
measure: Gestational age change in lung vibroacoustics
timeFrame: through study completion, an average of 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Washington
country: United States
facility: Medstar Georgetown University Hospital
state: District of Columbia
Study officials:
affiliation: Georgetown University Medical Center Pediatrics
name: Pinaki Panigrahi, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03514550: Effects of Anesthesia on Immunity in Cancer
Official title: Immunomodulatory Effects of Volatile and Total Intravenous Anesthesia for Patients With Renal Cancer
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Surgery
Renal Cancer
Lead sponsor: Meshalkin Research Institute of Pathology of Circulation
Sponsor class: NETWORK
First posted: 2018-05-02
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: The aim of the study is a comparative study of the cellular immunity response of patients operated on for kidney cancer under total intravenous and inhalational anesthesia.

Detailed description: The severity of perioperative immunosuppression is directly proportional to the degree of surgical stress. A series of experimental and clinical studies indicate a different effect of certain types of anesthesia on immunity. It is believed that surgical stress itself opens an opportunity for the recurrence of oncological diseases precisely due to the immunosuppressive effect. The aim of present pilot clinical study is to test a hypothesis that total intravenous anesthesia as superior to inhalational anesthesia in term of its effects on cell immunity among patients with kidney cancer.

Eligibility criteria: Inclusion Criteria:

* Surgery for renal cancer
* Signed informed concent

Exclusion Criteria:

* Propofol or sevoflurane intolerance
* Contraindications for epidural anesthesia
* Renal failure
* Hepatic failure
* Congestive heart failure
* Previous hemotherapy
* Hematological diseases

Primary outcomes:
measure: CD 16
timeFrame: postoperative day 1
Secondary outcomes:
measure: CD45
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: CD3
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: CD19
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: CD4
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: CD8
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: CD16
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: CD25
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
measure: HLA-DR
timeFrame: Baseline, end of surgery, postoperative days 1, 3-4, 7
Other outcomes:
Locations:
city: Novosibirsk
country: Russian Federation
facility: State Research Institute of Circulation Pathology
Study officials:
References:
Clinical trial NCT05965050: Effect Of Myofascial Release Technique With Ultrasound Therapy in Adults With Nonspecific Low Back Pain.
Official title: Effect Of Myofascial Release Technique With Ultrasound Therapy in Adults With Nonspecific Low Back Pain.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Low Back Pain
Lead sponsor: Superior University
Sponsor class: OTHER
First posted: 2023-07-28
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Low back pain is common problem the purpose of this research will be to determine the comparison of ultrasound therapy and myofascial release technique for treatment of low back pain in adults.

Detailed description: Low back pain is common problem the purpose of this research will be to determine the comparison of ultrasound therapy and myofascial release technique for treatment of low back pain in adults. To increase lumbar spine range of motion chest wall mobility and flexibility, reduction in level of lumbar disability

Eligibility criteria: Inclusion Criteria:

* Both male and female
* between age of 18 and 60 reported with chronic low back pain (lasting more than 3 months)

Exclusion Criteria:

* unresponsive psychologically disturbed patient
* people under 18
* Following coexisting conditions cancer, diabetes, pregnancy, cardiovascular system, gynecological disease.
* Neurological conditions, spine injury contraindicated to MFR treatment (infectious disease, viral and bacterial infections, active malignant disease, aneurysm
* Arthrodesis

Primary outcomes:
measure: Modified Oswestry disability index
timeFrame: 6 Months
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Azra Naheed Medical College, Superior University
state: Punjab
Study officials:
affiliation: Superior Uni
name: Abdul Wahab
role: STUDY_CHAIR
References:
Clinical trial NCT02026050: Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus
Official title: Phase 4 Study of Comparison of Postoperative Analgesic Effect of Intra-articular Dexamethasone and Dexamethasone Added to Bupivacaine in Interscalene Brachial Plexus Blockade for Arthroscopic Shoulder Surgery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Postoperative Pain
Keywords: dexamethasone
intraarticular injection
interscalene brachial plexus block
Lead sponsor: TC Erciyes University
Sponsor class: OTHER
First posted: 2014-01-01
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: the aim of this study was to investigate the analgesic efficacy of intra articular dexamethasone administration for arthroscopic shoulder surgery.

Detailed description: shoulder surgery can be very painful and interscalene brachial plexus block is the gold standard in the management of acute pain after shoulder surgery. various local anaesthetic mixtures can be used to prolong local anaesthesia duration and epinephrine , opioids and dexamethasone are frequently used for this purpose. dexamethasone has also been found the prolong the duration of lidocaine axillary blocks and intravenous regional anaesthesia. intraarticular administration of medicines can be used for management of joint pain and opioids , local anaesthetics and dexamethasone are used for this purpose.In addition, there are no studies available to compare the different treatment methods used in clinical practice directly.

Eligibility criteria: Inclusion Criteria:

* between 18-65 years
* arthroscopic shoulder surgery
* no known allergies to drugs
* ASA 1-2 patients

Exclusion Criteria:

* history of diabetes
* history of chronic pain treatment
* pregnancy
* severe bronchopulmonary disease
* systemic glucocorticoid use

Primary outcomes:
measure: analgesic consumption
timeFrame: postoperative 1 day
Secondary outcomes:
measure: visual analog scale
timeFrame: postoperative 1 day
Other outcomes:
Locations:
city: Kayseri
country: Turkey
facility: Erciyes university hospital
Study officials:
affiliation: TC Erciyes University
name: Fatih M KURT, Resident
role: PRINCIPAL_INVESTIGATOR
affiliation: TC Erciyes University
name: Gülen GÜLER, Prof.
role: STUDY_DIRECTOR
References:
Clinical trial NCT03791450: Investigation of Pancreaticoduodenectomy
Official title: A Multicenter Big⁃Sample Retrospective Study of Pancreaticoduodenectomy
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pancreaticoduodenectomy
Lead sponsor: Tongji Hospital
Sponsor class: OTHER
First posted: 2019-01-02
Enrollment: 10085
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who had underwent pancreaticoduodenectomy between 2008 to 2018.

Brief summary: The investigators intend to conduct a multicentre, big-sample, retrospective study to analysis the surgery results of pancreaticoduodenectomy and compare the different suture technique.

Detailed description: For patients with malignant or benign disease of the pancreatic head and periampullary region, pancreaticoduodenectomy is the only potential approach to radical cure. However, pancreaticoduodenectomy is consider as one of the most complex operations associated with a high rate of postoperative complications such as pancreatic fistula, delayed gastric emptying, hemorrhage, abscess, and sepsis. These complications increase the costs associated with pancreaticoduodenectomy. Numerous interventions and techniques have been introduced to decrease the morbidity. But there is little evidence for the superiority of one anastomotic technique over the others. Therefore, investigators intend to conduct a multicentre, big-sample, retrospective study to analysis the surgery results of pancreaticoduodenectomy and compare the different suture technique.

Eligibility criteria: Inclusion Criteria:

Patients who had underwent pancreaticoduodenectomy between 2008 to 2018.

Exclusion Criteria:

None

Primary outcomes:
measure: Incidence of Postoperative Pancreatic Fistula(POPF)
timeFrame: Within 30 days after surgery
Secondary outcomes:
measure: Morbidity
timeFrame: Within 90 days after surgery
measure: Mortality
timeFrame: Within 30 days after surgery
measure: Duration of operation
timeFrame: Intraoperative
measure: Length of hospital stay after surgery
timeFrame: From first day after surgery to release from hospital (anticipate 5 days minimally)
measure: Hospital costs
timeFrame: From first day after surgery to release from hospital (anticipate 5 days minimally)
Other outcomes:
Locations:
city: Wuhan
country: China
facility: Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
state: Hubei
Study officials:
References:
Clinical trial NCT03713450: Patient and Staff Safety During Aorto-iliac Revascularization Procedures Under Automated Fusion Imaging Guidance With Controls
Official title: A Prospective Single Centre Randomized Interventional Controlled Trial Comparing Patient and Staff Safety During Aorto-iliac Revascularization Procedures Under Automated Fusion Imaging Guidance With Controls
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Patient and Staff Radiation Exposure During Aorto-iliac Endovascular Revascularization
Keywords: Radiation
Contrast
Endovascular
Fusion imaging guidance
Iliac
Lead sponsor: Nantes University Hospital
Sponsor class: OTHER
First posted: 2018-10-19
Enrollment: 45
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Endovascular revascularization has revolutionized the field of vascular surgery and has become the first-choice treatment for peripheral arteries occlusive disease. However, the drawback of this technic is the X-ray exposure for both patients and staff and the iodinated contrast injection for the patient.

One way to reduce both radiation and contrast use is to use advanced imaging techniques allowing an overlay of a 3D vascular mask (from a pre-operative CT scan) onto the live X-ray image. This has been proven during endovascular aneurysm repair.

This advanced imaging application is currently available only in the latest expensive hybrid operating rooms, requires additional manoeuvre from the operator throughout the procedure, and may be X-rays and contrast consuming.

This trial will examine the clinical benefits based on patient and staff' radiation exposure during aorto-iliac revascularisation, of a new software imaging guidance, suitable for any theatre including those equipped with mobile C-arm, fully automated and with a radiation free overlay registration process.


Eligibility criteria: Inclusion Criteria:

* Male or female aged 18 or older,
* Patients scheduled for aorto iliac endovascular revascularisation,
* Pre-operative CT scan.

Exclusion Criteria:

* Women of childbearing age,
* Absence of preoperative CT scan,
* Emergency procedures.

Primary outcomes:
measure: Dose area product
timeFrame: The end of the procedure
Secondary outcomes:
measure: Number of DSA runs
timeFrame: The end of the procedure
measure: Air Kerma
timeFrame: The end of the procedure
measure: Fluoroscopy time
timeFrame: The end of the procedure
measure: Contrast volume
timeFrame: The end of the procedure
measure: Operative time
timeFrame: The end of the procedure
measure: Operator exposure
timeFrame: The end of the procedure
Other outcomes:
Locations:
city: Nantes
country: France
facility: Nantes University Hospital, Vascular surgery, Institut du Thorax
Study officials:
References:
Clinical trial NCT02444650: Measurement of Pulse Wave Velocity
Official title: Photoplethysmogram Measurement of Pulse Wave Velocity
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Healthy
Keywords: Correlation
pulse wave velocity measurement
tonometry
Lead sponsor: Nonin Medical, Inc
Sponsor class: INDUSTRY
Collaborators: name: Mayo Clinic
First posted: 2015-05-14
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Healthy normotensive and hypertensive subjects.

Brief summary: Optically-based data will be compared to tonometry to determine correlation of pulse wave velocity measurement.


Eligibility criteria: Inclusion Criteria:

* Between the ages of18-25 and 65-90 will be studied.
* Normotensive and hypertensive subjects
* Willing to provide informed consent

Exclusion Criteria:

* has finger deformities or amputations that will prohibit proper sensor placement
* pregnant or actively trying to get pregnant
* Cardiogreen or other intravascular/tissue dyes less than 5 hours prior to the study.

Primary outcomes:
measure: Optically based pulse wave velocity measurement correlation to the tonometry measure.
timeFrame: 2 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Rochester
country: United States
facility: Mayo Clinic
state: Minnesota
Study officials:
affiliation: Mayo Clinic
name: Timothy Curry, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: