Clinical trial NCT04757350: Objective Visual Quality Analysis System is Used in Cataract
Official title: Objective Visual Quality Analysis System is Used to Evaluate the Effect of Cataract Surgery and Manage Postoperative Complications
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Cataract
Keywords: cataract
Lead sponsor: Wuhan Union Hospital, China
Sponsor class: OTHER
First posted: 2021-02-17
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Union Hospital Eye Clinic

Brief summary: The Objective Visual Quality Analysis System (OQAS) is a new inspection technology used to objectively assess the visual quality of the human eye. The investigators use this advanced technology to evaluate and follow up cataract patients before and after surgery, and observe the incidence, severity, and treatment effects of postoperative complications such as postoperative complications, and analyze the severity and artificial The influence of lens type, postoperative time, systemic diseases and other factors on the effect of cataract surgery, in order to discover the key factors that affect the effect of cataract surgery and the management of complications, and provide a useful reference for improving the level of cataract prevention and treatment in China

Detailed description: The Objective Visual Quality Analysis System (OQAS) is a new inspection technology used to objectively assess the visual quality of the human eye. It can detect the impact of ocular refractive system diseases on the objective visual quality of patients. It is currently mainly used to assess the progress of cataracts and help selection the timing of surgery has achieved good clinical results. Before the emergence of OQAS, the rating of cataracts largely relied on the subjective experience of physicians, and OQAS could accurately assess the effects of cataracts on the visual quality of the human eye by quantitatively detecting the light scattering index (OSI) of the refractive medium of the human eye. The impact provides a quantitative evaluation basis for the diagnosis and treatment of cataract and research. However, the application of OQAS in cataract surgery effect evaluation and postoperative complications management is still lacking. After cataract surgery, although the cloudy lens nucleus and cortex have been removed, the original refractive error, vitreous opacity, postoperative posterior capsule folds, posterior dysfunction and many other factors may still affect the objective of the human eye visual quality, and ordinary visual inspection is difficult to find this effect . In addition, preoperative OSI and other indicators of cataract, as an exposure factor, may affect the incidence of postoperative complications, such as after-cataract, macular edema, etc. It is worthy of further study. The application of OQAS can accurately assess the improvement of objective visual quality after cataract surgery, and find and remove other factors that affect OSI. In addition, for one of the most common complications after cataract surgery-after-onset disorder, there is no uniform rating standard in the academic circles, and OQAS can provide objective data for the rating of after-onset disorder, so as to provide information on the postoperative complications such as late-onset disorder. Provide reference for the management of . The research team intends to use OQAS to evaluate and follow up cataract patients before and after surgery, and observe the incidence, severity, and treatment effects of postoperative complications such as after-cataract, analyze the severity of cataract or after-cataract, and intraocular lens The influence of factors such as type, postoperative time, systemic disease on the effect of cataract surgery. We will also rate the posterior disorder based on OSI, and examine the effects and risks of different grades of posterior disorder after laser capsulotomy and other treatments, in order to use OQAS to better guide cataract surgery and postoperative complications management.

Eligibility criteria: Inclusion Criteria:

1. Cataract patients aged 18-90 or patients after cataract surgery；
2. Signed and dated informed consent；
3. Commit to abide by the research procedures and cooperate with the implementation of the whole process research

Exclusion Criteria:

1. Obvious conjunctivitis；
2. Obvious corneal epithelial punctate staining, corneal epithelial shedding；
3. Keratitis；
4. Uveitis；
5. Corneal scar；
6. Severe vitreous opacity or hemorrhage；
7. Other situations deemed unsuitable for inclusion in this study after evaluation by ophthalmologists.

Primary outcomes:
measure: Change from visual acuity at 6 months
timeFrame: 6 months
measure: Change from Objective Scatter Index at 6 months
timeFrame: 6 months
measure: Change from Contrast Sensitivity at 6 months
timeFrame: 6 months
measure: Change from Patient Satisfaction Scale at 6 months
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Wuhan
country: China
facility: Union Hospital
state: Hubei
Study officials:
affiliation: Wuhan Union Hospital, China
name: yukan huang, professor
role: STUDY_CHAIR
References: