Clinical trial NCT06152055: Clinicopathological Profile of Head and Neck Cancers in Army Hospital of Nepal
Official title: Clinicopathological Profile of Head and Neck Cancers in Army Hospital of Nepal - A Retrospective Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Head and Neck Cancer
Keywords: Head and Neck Cancer
Radiotherapy
Chemotherapy
Lead sponsor: Tribhuvan University, Nepal
Sponsor class: OTHER
First posted: 2023-11-30
Enrollment: 76
Sex: ALL
Minimum age (years): 17
Maximum age (years): 84
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Study population was selected from the tertiary care centre of Nepal.

Brief summary: This is a observational study conducted at the department of Ear ,Nose and Throat -Head and Neck Surgery (ENT-HNS) of Shree Birendra Hospital ,a tertiary health care centre of Nepal. Head and Neck cancers are the sixth most common cancer in the world. Data was collected from the medical records of Head and Neck Cancer patients who underwent treatment between May 2022 to April 2023.The main aim of the study was to know about the common cancers of head and neck region and their distribution according to the site. Also to know the stage of the presentation with treatment modalities in the tertiary health care centre of Nepal.

Detailed description: This is a retrospective study to know the prevalence of Head and Neck Cancer at the department of ENT- Head and Neck Surgery of Shree Birendra Hospital ,a tertiary health care centre of Nepal .Head and neck cancers are malignant neoplasms that develops in oral cavity, nasal cavities, paranasal sinuses,nasopharynx, oropharynx, hypopharynx, ear, scalp, salivary gland and neck,Data was collected from the medical records of Head and Neck Cancer patients who underwent treatment between May 2022 to April 2023. Data considered of demographic details of age, sex, diagnosis, subsite specific Head and Neck Cancers, treatment modality and histopathology. The data was analyzed using Stastical Package for Social Sciences (SPSS) version 22. Pearson's chi-square test was applied and p value \<0.05 was considered statistically significant.

Eligibility criteria: Inclusion Criteria:

* All histologically proven cases of head and neck region.

Exclusion Criteria:

* Patient's record with incomplete data.

Primary outcomes:
measure: Age - wise Distribution of Head and Neck Cancers (HNCs)
timeFrame: 1 year
measure: : Distribution of HNCs according to subsite
timeFrame: 1 year
measure: Histopathology of HNCs
timeFrame: 1 year
measure: Tumor, Nodes, Metastasis (TNM) staging of HNC
timeFrame: 1 year
measure: Treatment provided to HNC patients
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Kathmandu
country: Nepal
facility: Shree Birendra Hospital
Study officials:
affiliation: Shree Birendra Hospital
name: Reeba Karki, MS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Chin D, Boyle GM, Porceddu S, Theile DR, Parsons PG, Coman WB. Head and neck cancer: past, present and future. Expert Rev Anticancer Ther. 2006 Jul;6(7):1111-8. doi: 10.1586/14737140.6.7.1111.