Clinical trial NCT06349603: Physiotherapy Approach for Susac Syndrome
Official title: Integrated Physiotherapy Approach for Susac Syndrome: A Comprehensive Case Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Susac Syndrome
Keywords: Physiotherapy
Lead sponsor: Rehabilitation Centre Zivot
Sponsor class: OTHER
First posted: 2024-04-05
Enrollment: 1
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study population consisted of a single adolescent patient diagnosed with Susac syndrome, aged 17 years. The patient presented with motor impairments and functional limitations attributed to Susac syndrome, including difficulties in mobility and muscle weakness. No significant comorbidities were reported, and the patient was medically stable to participate in a 12-week intensive physiotherapy program. Informed consent was obtained from the participant and their legal guardian prior to enrollment in the study."

Brief summary: Susac's syndrome is a rare autoimmune disorder characterised by a triad of encephalopathy (brain dysfunction), branch retinal artery occlusion (loss of vision) and sensorineural hearing loss. This study presents the case of a patient undergoing intensive physiotherapy intervention following an injury, focusing on assessments such as volume and range of motion measurements, manual muscle tests, and pain intensity evaluations using various scales.

Detailed description: The patient, aged 17, initially presented with severe limitations in mobility, diagnosed with Susac syndrome. Requiring assistance to walk even short distances due to fear and insecurity. Through a structured physiotherapy program spanning several months, various assessments were conducted, including manual muscle tests and circumference measurements. Significant improvements were observed for muscle function, upper and lower limb circumferences, and performance in mobility tests.

Eligibility criteria: Inclusion Criteria:

* Confirmed diagnosis of Susac syndrome.
* Willingness and ability to participate in a 12-week intensive physiotherapy program.
* Stable medical condition that allows participation in physiotherapy without significant risks.
* Ability to provide informed consent for participation in the study.

Exclusion Criteria:

* Presence of severe comorbidities or medical conditions that would interfere with participation in physiotherapy or confound the study outcomes.
* Inability to comprehend or follow the instructions for physiotherapy exercises.
* Pregnancy, as certain physiotherapy modalities may not be suitable during pregnancy.
* Any other condition or circumstance that, in the opinion of the investigator, would compromise the safety or validity of participation in the study.

Primary outcomes:
measure: Mobility and Muscle Strength Improvement
timeFrame: Assessed at baseline and after 12 weeks of intensive therapy.
measure: Muscle Strength Improvement Outcome Measure
timeFrame: Assessed at baseline and after 12 weeks of intensive therapy.
measure: Pain Intensity Outcome Measure
timeFrame: Assessed at baseline and after 12 weeks of intensive therapy.
Secondary outcomes:
Other outcomes:
Locations:
city: Mostar
country: Bosnia and Herzegovina
facility: Rehabilitation centre Život
Study officials:
References:
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