Clinical trial NCT00276510: A Study of EGb 761® (Tanakan®) in Dementia of Alzheimer Type Onset in Patients Suffering From Memory Complaints
Official title: Efficacy and Tolerance of EGb 761® 120mg Two Times a Day on Dementia of Alzheimer Type's Onset in Patients Suffering From Memory Complaints. A Randomised, Double-blind, Multicentre, Parallel Groups, Placebo Controlled Phase IIIb/IV Study in Elderly Over 70
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Memory Disorders, Age-Related
Retention Disorders, Cognitive
Lead sponsor: Ipsen
Sponsor class: INDUSTRY
First posted: 2006-01-13
Enrollment: 2878
Sex: ALL
Minimum age (years): 70
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to determine whether Tanakan® is effective at slowing the progression from memory complaint to dementia of Alzheimer's type.


Eligibility criteria: Inclusion Criteria:

* Spontaneously reporting a memory complaint
* Short anxiety battery test \< 6, (only if patient screened at GP site)
* Geriatric depression scale \< 15
* Mini-mental state (MMS) \> 25 in GP's office (in hospital site MMS is done as complementary scale)

Exclusion Criteria:

* Objective memory impairment
* Clinician rated dementia staging system \> 0.5
* Mini-mental state \< 25
* Dementia, past history of seizures, Parkinson disease

Primary outcomes:
measure: EGb 761® efficacy on conversion rate of memory complaint to dementia of Alzheimer type by a survival analysis
timeFrame: Baseline, month 12, 24, 36, 48 and 60
Secondary outcomes:
measure: Efficacy on rate of cognitive abilities decline
timeFrame: Baseline, month 12, 24, 36, 48 and 60
measure: Effect on concomitant diseases
timeFrame: Baseline, month 12, 24, 36, 48 and 60
measure: Concomitant treatments' reports
timeFrame: Baseline, month 12, 24, 36, 48 and 60
measure: Global evaluation of memory complaint by the patient
timeFrame: Baseline, month 12, 24, 36, 48 and 60
measure: Clinical safety
timeFrame: Baseline, month 12, 24, 36, 48 and 60
Other outcomes:
Locations:
city: Agde
country: France
facility: 1 rue de l'Orient
city: Aix les Bains
country: France
facility: 3 Avenue de Marlioz
city: Ales
country: France
facility: 3 rue Auguste Delaune
city: Amboise
country: France
facility: 17 rue du Cardinal Georges d'Amboise
city: Amboise
country: France
facility: 17 rue Manuel
city: Ancerville
country: France
facility: 83 rue Nicolas et Paul Paquet
city: Andernos Les Bains
country: France
facility: 10 bd De La Republique
city: Andernos Les Bains
country: France
facility: 107 bd De La Republique
city: Andernos
country: France
facility: 19 rue Jean Saccheti
city: Angers
country: France
facility: 128 Rue Bressigny
city: Angers
country: France
facility: 18 rue Martin Luther King
city: Angers
country: France
facility: 2 boulevard Jacques Millot
city: Angers
country: France
facility: 21 bd Roi René
city: Angers
country: France
facility: 25, rue St Nicolas
city: Angers
country: France
facility: 59 Boulevard Joseph Bédier
city: Angers
country: France
facility: 61 Ave Jean XXIII
city: Angers
country: France
facility: 68A rue d'Orgemont
city: Angers
country: France
facility: Residence le Paradis Bat 17, 74-78 rue Volney
city: Angers
country: France
facility: Centre Hospitalier Universitaire Hotel Dieu Gerontologie Clinique 4 rue Larrey
city: Angers
country: France
facility: 111 rue de la Chalouère
city: Angers
country: France
facility: 4 rue Saint Jacques
city: Angers
country: France
facility: 4, rue St Jacques
city: Angers
country: France
facility: 7 rue Thiers
city: Antibes
country: France
facility: 1172 route de Grasse Ste Elisabeth
city: Antibes
country: France
facility: 20 boulevard Albert 1er
city: Antibes
country: France
facility: 700 av. Jules Grec
city: Ars sur Moselle
country: France
facility: 26 R Pres Wilson
city: Aubagne
country: France
facility: Avenue Joseph Lafont
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country: France
facility: Groupe Piettot Bâtiment 2
city: Aubervilliers
country: France
facility: 37-39 boulevard Anatole France
city: Aubevoye
country: France
facility: 26 av. Charles de Gaulle
city: Audenge
country: France
facility: 3 Avenue de Verdun
city: Aumetz
country: France
facility: 27 rue Maréchal Foch
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country: France
facility: 2 bis route de Miremont
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country: France
facility: 70 bis rue Etienne Billieres
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facility: 17 rue des Ecoles
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country: France
facility: 17, rue des Ecoles
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country: France
facility: 30 Ter Avenue Pierre Mendès
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facility: Rd point de Gal de Gaulle
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facility: Centre Hospitalier Pellegrin-Tripode Service de Neurologie Place Amelie Raba-Leon
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country: France
facility: Centre Hospitalier Jacques Coeur Hopital Taillegrain Centre de Gerontologie des Pres Fichaux 6 rue Taillegrain
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country: France
facility: Centre Hospitalier Jacques Coeur Hôpital Taillegrain
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country: France
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city: Lille
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city: Lille
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city: Lille
country: France
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city: Lille
country: France
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country: France
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city: Lille
country: France
facility: Hopital Roger Salengro Service de Neurologie C rue Emile Laine
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country: France
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city: Lormont
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city: Lormont
country: France
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country: France
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city: Lunel Viel
country: France
facility: 70 rue Andre Auguste
city: Lussan Adeilhac
country: France
facility: L'ancien Presbytere
city: Luynes
country: France
facility: 10, avenue Robert Daugey
city: Manduel
country: France
facility: 1 Place Bellecroix
city: Marly
country: France
facility: 1 bis avenue des Coteaux
city: Marly
country: France
facility: 2 Avenue Long Pré
city: Mars La Tour
country: France
facility: 8 Rue Georges Thiebaux
city: Marseille
country: France
facility: 1 boulevard Montricher
city: Marseille
country: France
facility: 134, rue Félix Pyat
city: Marseille
country: France
facility: 81 rue Jaubert
city: Marseille
country: France
facility: 81 rue Jaubert
city: Marseille
country: France
facility: 12 Bld Des Neiges
city: Marseille
country: France
facility: 325 avenue de Mazargues
city: Marseille
country: France
facility: 38 bld Rodocanachi
city: Marseille
country: France
facility: 431 avenue de Marzargues
city: Marseille
country: France
facility: 63, boulevard Rabateau
city: Marseille
country: France
facility: Hopital St Joseph Service de Neurologie 26 boulevard Louvain
city: Marseille
country: France
facility: 2 Avenue Jean Bouin
city: Marseille
country: France
facility: 2 chemin de Morgiou
city: Marseille
country: France
facility: 23 Bd de la Concorde
city: Marseille
country: France
facility: 250 Bd Romain Rolland
city: Marseille
country: France
facility: Groupe Medical de Mazargues 1 av de la Martheline
city: Marseille
country: France
facility: 13 rue St Eloi
city: Marseille
country: France
facility: 90 Boulevard de Saint Loup
city: Marseille
country: France
facility: Les Camoins 58 Traverse de St Menet
city: Marseille
country: France
facility: 21 Traverse des Rosiers
city: Marseille
country: France
facility: 253 ch. de la Madrague-Ville
city: Marseille
country: France
facility: Hopital STe Marguerite Unite de Neurologie 270 boulevard de STe Marguerite
city: Martignas
country: France
facility: 6 av. des martyrs de la Resistance
city: Martigues
country: France
facility: 5 Avenue du Pdt Allende
city: Martigues
country: France
facility: Espace Vénitien 1 av Pres Salvador Allende
city: Martigues
country: France
facility: Espace Vénitien
city: Maze
country: France
facility: 75 rue Principale
city: Meaux
country: France
facility: 1 Square Chardin
city: Meaux
country: France
facility: Centre Commercial La Verriere place Beauval
city: Mercy Le Bas
country: France
facility: 11 rue des Tilleuls
city: Merignac
country: France
facility: 206 av de l'Argonne
city: Metz
country: France
facility: Hôpital Felix Marechal 1 rue Xavier Roussel
city: Metz
country: France
facility: 203 Rue de Vallieres
city: Meudon
country: France
facility: 10 rue de la Republique
city: Meylan
country: France
facility: 41, Avenue Plaine Fleurie
city: Meylan
country: France
facility: 7 rue de l'Oisans
city: Meze
country: France
facility: Domus Médica
city: Milhaud
country: France
facility: 2 bis Place du Castellas
city: Miniac Morvan
country: France
facility: 27 rue de la Croix Thomas
city: Mire
country: France
facility: 32 rue Cité
city: Moirans
country: France
facility: 12 Rue Du 8 Mai 1945
city: Montigny les Metz
country: France
facility: 221 R de Pont A Mousson
city: Montigny les Metz
country: France
facility: 5 rue des Roses
city: Montjean-sur-Loire
country: France
facility: 2 place de L'Eglise
city: Montpellier
country: France
facility: 2, rue Delpech
city: Montpellier
country: France
facility: 25 av de St Lazare - Le Prieure II
city: Montpellier
country: France
facility: 32 avenue G Clémenceau
city: Montpellier
country: France
facility: 32, Avenue Georges Clémenceau
city: Montpellier
country: France
facility: 41 Bld Du Jeu de Paume
city: Montpellier
country: France
facility: 7 ter rue Rigaud
city: Montpellier
country: France
facility: 82 avenue d'Assas
city: Montpellier
country: France
facility: 82, avenue d'ASSAS
city: Montpellier
country: France
facility: 9 avenue d'Assas
city: Montpellier
country: France
facility: 9, Avenue d'Assas
city: Montpellier
country: France
facility: 11 rue Monge
city: Montpellier
country: France
facility: 11 rue Mongre
city: Montpellier
country: France
facility: 20 avenue de Toulouse
city: Montpellier
country: France
facility: 48 rue Robespierre
city: Montpellier
country: France
facility: 57, route de Lavérune
city: Montpellier
country: France
facility: 59 av. de Toulouse- Bat B
city: Montpellier
country: France
facility: 7 rue du Grau
city: Montpellier
country: France
facility: 12 Faubourg Boutonnet
city: Montpellier
country: France
facility: 22 Faubourg Boutonnet
city: Montpellier
country: France
facility: Hopital Gui de Chauliac 80 rue Augustin Fliche
city: Montreuil-Juigne
country: France
facility: 8 rue Pierre Mendès France
city: Montrouge
country: France
facility: 9 rue Sadi Carnot
city: Mouchin
country: France
facility: 113 Route de Douai
city: Mouliherne
country: France
facility: 11 Rue du Maine
city: Mouliherne
country: France
facility: 6, route d'Anjou
city: Moulin Les Metz
country: France
facility: 18 Rue de Metz
city: Moussac
country: France
facility: Rue du Rieu
city: Moutiers
country: France
facility: 13 rue Clémenceau
city: Muret
country: France
facility: 48, ave Jacques Douzans
city: Muret
country: France
facility: 48, avenue Jacques Douzans
city: Murs Erigne
country: France
facility: 25 rue Valentin Desormeaux
city: Nancy
country: France
facility: 34 Rue de Metz
city: Nancy
country: France
facility: 82 rue Saint Georges
city: Nantes
country: France
facility: 15 rue Jeanne d'Arc
city: Nantes
country: France
facility: 181 rue Paul Bellamy
city: Nantes
country: France
facility: 2 Bd Amiral Courbet
city: Nantes
country: France
facility: 23 rue Racine
city: Nantes
country: France
facility: 29 bis rue Pelleterie
city: Nantes
country: France
facility: 46 bis bd Gabriel Guist'Hau
city: Nantes
country: France
facility: 59 bld Gaston Serpette
city: Nantes
country: France
facility: 71 rue du Coudray
city: Nantes
country: France
facility: 88 rue Gambetta
city: Nantes
country: France
facility: Hopital Bellier Service de Geronotologie 41 rue Curie
city: Nantes
country: France
facility: 42 rue du Roi Baco
city: Nantes
country: France
facility: 7 rue Blancho
city: Nantes
country: France
facility: Cabinet de Neurologie - Consultations
city: Nantes
country: France
facility: 101 bld de Doulon
city: Nantes
country: France
facility: 134 rue du Croissant
city: Nantes
country: France
facility: 142 bld Robert Schuman
city: Nantes
country: France
facility: 15 rue Guillaume Grootaers
city: Nantes
country: France
facility: 23 bld Chauviniere
city: Nantes
country: France
facility: 27 boulevard des Americians
city: Nantes
country: France
facility: 34 rue de la Gourmette
city: Nantes
country: France
facility: 46, boulevard Jules Verne
city: Nantes
country: France
facility: 58 bld Jules Verne
city: Nantes
country: France
facility: 63 rue de la Bottière
city: Navailles Angos
country: France
facility: Route de Morlaas
city: Neuville Sur Escaut
country: France
facility: 12 rue Pasteur
city: Neuville sur Escaut
country: France
facility: 12, rue Pasteur
city: Nice
country: France
facility: 16 rue Vernier
city: Nice
country: France
facility: 30, rue Gioffredo
city: Nice
country: France
facility: 54 bld François Grosso
city: Nice
country: France
facility: 6, rue Rossini
city: Nice
country: France
facility: Hopital de Cimiez Pavillon Mossa 4 avenue de la Reine Victoria
city: Nice
country: France
facility: Hôpital Pasteur
city: Nice
country: France
facility: 32 rue Auguste Gal
city: Nice
country: France
facility: 47 Bis, Rue Barberis
city: Nice
country: France
facility: 5 boulevard du General Delfino
city: Nice
country: France
facility: 5 rue Smolett
city: Nice
country: France
facility: L'Esperanza 9 rue de la République
city: Nimes
country: France
facility: Maison Médical Mutualiste
city: Nimes
country: France
facility: Centre Raymond Ruffi 12 rue Alexandre Ducros
city: Nimes
country: France
facility: Cabinet Medical place des Goelands
city: Nort Sur Erdre
country: France
facility: 30 Bd de la Gare
city: Nort Sur Erdre
country: France
facility: 4 bld de Strasbourg
city: Noveant Sur Moselle
country: France
facility: 8 rue Foch
city: Nueil
country: France
facility: 20 Place d'Armes
city: Orly
country: France
facility: 2 Allée des Glycines
city: Orthez
country: France
facility: 2 avenue Pesqué
city: Orthez
country: France
facility: 2, Avenue Pesqué
city: Orthez
country: France
facility: 3 rue Madame
city: Ouistreham
country: France
facility: 125, rue Gambetta
city: Pacy sur Eure
country: France
facility: 16 rue Aristide Briand
city: Pantin
country: France
facility: 31 rue Jean L'olive
city: Parcay Les Pins
country: France
facility: route de Gizeux
city: Paris
country: France
facility: 19 boulevard Morland
city: Paris
country: France
facility: 1 rue Villersexel
city: Paris
country: France
facility: 6 rue de la Motte-Piquet
city: Paris
country: France
facility: 88 rue de Sevres
city: Paris
country: France
facility: 9 Rue de Montessuy
city: Paris
country: France
facility: 3, Rue Pierre Le Grand
city: Paris
country: France
facility: 40 rue du Faubourg Montmartre
city: Paris
country: France
facility: 15 rue de Chabrol
city: Paris
country: France
facility: 41 rue de la Grange aux Belles
city: Paris
country: France
facility: 26, rue Picpus
city: Paris
country: France
facility: 167, boulevard Vincent Auriol
city: Paris
country: France
facility: 74 rue Dunois
city: Paris
country: France
facility: Hôpital Broca - Service de Gérontologie Clinique 54-56 rue Pascal
city: Paris
country: France
facility: 191 rue d'Alésia
city: Paris
country: France
facility: 2 rue de la Briqueterie
city: Paris
country: France
facility: 96 avenue Maine
city: Paris
country: France
facility: 81, rue de Rome
city: Paris
country: France
facility: 33, rue Marx Dormoy
city: Paris
country: France
facility: 34 rue Hermel
city: Paris
country: France
facility: 13 Villa Curial
city: Paris
country: France
facility: 20, rue du Télégraphe
city: Paris
country: France
facility: 7 Rue Saint Blaise
city: Paris
country: France
facility: 79 rue Boissiere
city: Pau
country: France
facility: 1 Avenue Mirabelle
city: Pau
country: France
facility: 28 rue Castelnau
city: Pau
country: France
facility: 69 rue du 14 Juillet
city: Pau
country: France
facility: Centre Hospitalier des Pyrenees Department de Psychogeriatrie 29 av du Marechal Leclerc
city: Pau
country: France
facility: Centre Hospitalier des Pyrénées
city: Perols
country: France
facility: 2, rue de l'Hôtel de Ville
city: Pessac
country: France
facility: 153 Avenue du Général Leclerc
city: Pignan
country: France
facility: Le forum
city: Pinsaguel
country: France
facility: 1 Impasse Pasteur
city: Pinsaguel
country: France
facility: 83 rue Andorre
city: Podensac
country: France
facility: 18 place Gambetta
city: Pont A Mousson
country: France
facility: 14 Rue Philippe de Gueldres
city: Pont A Mousson
country: France
facility: 170 , avenue des Etats-Unis
city: Pont A Mousson
country: France
facility: 47, boulevard Ney
city: Pont A Mousson
country: France
facility: 7 rue du Cardinal Mathieu
city: Pont De L'arche
country: France
facility: 3 bis rue Cacheleux
city: Pont-de-l'Arche
country: France
facility: 35bis rue du Général de Gaulle
city: Pornichet
country: France
facility: 1 place Aristide Briand
city: Pornichet
country: France
facility: 16 av. du Littoral Ste Marguerite
city: Pornic
country: France
facility: 26, rue de Tourte
city: Port De Bouc
country: France
facility: Immeuble "Le Roc Rose"
city: Potigny
country: France
facility: 69 rue du Général Leclerc
city: Potigny
country: France
facility: 69, rue du Général Leclerc
city: Poulx
country: France
facility: 169 , rue de l'Avenir
city: Preignac
country: France
facility: BP 22-23 rue republique
city: Pulnoy
country: France
facility: 24 avenue Charles de Gaulle
city: Quarouble
country: France
facility: 7 rue Gambetta
city: Quint Fonsegrives
country: France
facility: Cours Goudouli
city: Raimbeaucourt
country: France
facility: 141 rue Roger Salengro
city: Ramonville Saint Agne
country: France
facility: 22 avenue de Tolosane
city: Ramonville Saint Agne
country: France
facility: 22 avenue Tolosane
city: Ramonville
country: France
facility: 12, rue Louis Braille
city: Rauzan
country: France
facility: La Garenne
city: Renaze
country: France
facility: 11, rue du Fresne
city: Renaze
country: France
facility: Rue Fresnes
city: Rennes
country: France
facility: 15 rue Emile Souvestre
city: Rennes
country: France
facility: Cabinet de Neurologie 4 av Charles Tillon
city: Rennes
country: France
facility: Cabinet de Neurologie
city: Rennes
country: France
facility: Centre Commercial La Bellangerais
city: Rennes
country: France
facility: Centre Espace Performance
city: Restigne
country: France
facility: 3, Rue de la petite Mairie
city: Reze
country: France
facility: Immeuble Athéna 62 bis rue Aristide Briand
city: Rieumes
country: France
facility: 11 rue Sagazan
city: Roquemaure
country: France
facility: 9 Place de la Mairie
city: Roquevaire
country: France
facility: Quai le Repos, ZAC St Estève
city: Rouans
country: France
facility: 13 rue de Messan
city: Roubaix
country: France
facility: 91 avenue Jean Lebas
city: Rouen
country: France
facility: 106 bis Rampe Bouvreuil
city: Rouen
country: France
facility: 45 Boulevard de l'Yser
city: Rouen
country: France
facility: Hôpital Charles Nicolle Department de Neurologie 1, rue de Germont
city: Rouen
country: France
facility: 102 rue Méridienne
city: Sains Orens De Gameville
country: France
facility: 6 rue Soye
city: Saint Avertin
country: France
facility: 30 Avenue du Général de Gaulle
city: Saint Barthelemy d'Anjou
country: France
facility: 4, rue Manet
city: Saint Briac
country: France
facility: 13 rue du Commandant Thoreux
city: Saint Broladre
country: France
facility: 4 rue Orme
city: Saint Cyr Sur Loire
country: France
facility: 103 rue Fleurie
city: Saint Georges d'Orques
country: France
facility: 6, rue de Courpouyran
city: Saint Gilles
country: France
facility: 15 bis Avenue Marcellin Berthelot
city: Saint Girons
country: France
facility: 30 bis avenue Gallieni
city: Saint Herblain
country: France
facility: 2 impasse Dublin
city: Saint Herblain
country: France
facility: 27 rue d'Aquitaine
city: Saint Just
country: France
facility: 48 avenue Condamine
city: Saint Laurent Du Var
country: France
facility: 22 avenue du Général Leclerc Les Bougainvillées
city: Saint Malo
country: France
facility: 63 Chaussée du Sillon
city: Saint Mamert Du Gard
country: France
facility: Impasse Dr Adrien Gory
city: Saint Mars du Désert
country: France
facility: 3, Rue Du 3 Août 1944
city: Saint martin du Bois
country: France
facility: 34 rue Prieuré
city: Saint Max
country: France
facility: 9, Résidence Haut Rivage, Rue Jean Xxiii
city: Saint Nazaire
country: France
facility: 3, rue du Pertuischaud
city: Saint Nazaire
country: France
facility: 9, Route du Fort de l'Eve
city: Saint Ouen
country: France
facility: 1 bis rue Godillot
city: Saint Privat la Montagne
country: France
facility: 1 rue Canot
city: Saint Raphael
country: France
facility: 16, Boulevard Darby - Valescure
city: Saint Sebastein Sur Loire
country: France
facility: 7 place Cambronne
city: Saint Sebastien
country: France
facility: 2, rue Jean Jaurès
city: Saint Sebastien
country: France
facility: 25, avenue de la Martellière
city: Saint Serin
country: France
facility: 19, Avenue de Verdun
city: Saint-Amand Mont-Rond
country: France
facility: 61 rue Anatole France
city: Saint-Amand
country: France
facility: 59 Pl. Du 11 Novembre 1918
city: Saint-Anastaise
country: France
facility: Rue des Oratoires
city: Saint-Brevin-les-Pins
country: France
facility: 245, avenue Mindin
city: Saint-Georges-d-Orques
country: France
facility: Rue de Clairdouy
city: Saint-Georges-de-Montaigu
country: France
facility: 106, Place du Gué des Joncs
city: Saint-Georges-des-Groseilliers
country: France
facility: 2 rue du Prieuré
city: Saint-Georges
country: France
facility: 60, Impasses des deux moulins
city: Saint-Girons
country: France
facility: Boulevard du Général de Gaulle
city: Saint-Herblain
country: France
facility: 22 av. des Thebaudieres
city: Saint-Hilaire-de-Chaleons
country: France
facility: ZA la Petite Croix
city: Saint-Jean-des-Linieres
country: France
facility: 11 Route de La Foret
city: Saint-Macaire-en-Mauges
country: France
facility: 53 Bd du 8 mai 1945
city: Saint-Mandrier
country: France
facility: 1 Place du 11 Novembre
city: Saint-Max
country: France
facility: 38 rue Hector Berlioz
city: Saint-Medard-en-Jalles
country: France
facility: 112 av Montesquieu
city: Saint-Medard
country: France
facility: 69 avenue Montaigne
city: Saint-Pierre-Montlimart
country: France
facility: 4, avenue du Petit Montrevault
city: Saint-Pierre-sur-Dives
country: France
facility: 50 rue Bosq
city: Saint-Quentin-la-Poterie
country: France
facility: Avenue du 14 Juillet
city: Saint-Sebastien-de-Morsent
country: France
facility: 1 allee Jean Restout
city: Sainte Foy De Peyrollieres
country: France
facility: Route Lombez
city: Sainte-Foy De Peyrollieres
country: France
facility: Route Lombez
city: Sainte-Foy-la-Grande
country: France
facility: 146 av de la République
city: Sainte-Gemmes
country: France
facility: 3 rue Moulin du Pain
city: Salies De Bearn
country: France
facility: Quart Thermal
city: Saussan
country: France
facility: 6 Allee Du Merlot
city: Sautron
country: France
facility: 30 rue de la Vallee
city: Sautron
country: France
facility: 30 rue Vallée
city: Savigny le Temple
country: France
facility: 1, Allée du Mistral
city: Savonnieres
country: France
facility: 21 rue Chatonnay
city: Segre
country: France
facility: Place du Port
city: Sens de Bretagne
country: France
facility: 3 place de la Gare
city: Sercoeur
country: France
facility: 72, route Châtel
city: Serifontaine
country: France
facility: 12 rue Jean Boyer
city: Serres Castets
country: France
facility: 2 route de Sauvagnon
city: Sete
country: France
facility: 11 rue Football
city: Sete
country: France
facility: 12 rue Gabriel Péri
city: Sete
country: France
facility: 41 rue Pierre Sémard
city: Sete
country: France
facility: 9 rue Alsace Lorraine
city: Sete
country: France
facility: Résidence Tarentelle Place E. Herriot
city: Seysses
country: France
facility: 14 rue Boltar
city: Seysses
country: France
facility: 60 route d'Ox
city: Sisteron
country: France
facility: 22 Place du Docteur Robert
city: Somain
country: France
facility: 41 rue Faidherbe
city: Somain
country: France
facility: 43, rue Faidherbe
city: Sotteville les Rouen
country: France
facility: 10 rue Benoît Malon
city: Sotteville les Rouen
country: France
facility: 33 rue Littre
city: St Jean De Vedas
country: France
facility: 5 rue Daniel Casanova Le Parc des Amandiers
city: St Max
country: France
facility: 63 rue Alexandre 1er
city: St Medard en Jalles
country: France
facility: 15, avenue Montaigne
city: St Nazaire
country: France
facility: 107 rue de Pornichet
city: St Pierre Sur Dives
country: France
facility: 50 rue Bosq
city: Thouars
country: France
facility: 27 rue Gaston Chéreau
city: Tierce
country: France
facility: 1 Ave des Erables
city: Tilly Sur Seulles
country: France
facility: 1 Chemin Courperron
city: Tinteniac
country: France
facility: 1 rue de l'Ecotay
city: Toufflers
country: France
facility: 1 Rue des Deportés
city: Toufflers
country: France
facility: 1, rue des Ecoles
city: Toulenne
country: France
facility: 60 av Du 8 Mai 1945
city: Toulouse
country: France
facility: 11 rue De Metz
city: Toulouse
country: France
facility: 2, rue Paradoux
city: Toulouse
country: France
facility: 26 av. Jean Rieux
city: Toulouse
country: France
facility: 35 rue Remusat
city: Toulouse
country: France
facility: 68 allee Jean Jaures
city: Toulouse
country: France
facility: 76 allee Jean Jaures
city: Toulouse
country: France
facility: Centre Hospitalier de Purpan Service de Neurologie place du Docteur Baylac
city: Toulouse
country: France
facility: 135 rue Henri Desbals
city: Toulouse
country: France
facility: 3 rue Vincent Van Gogh
city: Toulouse
country: France
facility: 3 rue Vincent Van Gough
city: Toulouse
country: France
facility: 25 Bld des minimes
city: Toulouse
country: France
facility: 3 rue Saint Famille
city: Toulouse
country: France
facility: 44 av Etienne Billieres
city: Toulouse
country: France
facility: 48 all. Charles de Fitte
city: Toulouse
country: France
facility: 52 av. de Grande Bretagne
city: Toulouse
country: France
facility: 8 pl. Interieure St Cyprien
city: Toulouse
country: France
facility: 1 rue Notre Dame
city: Toulouse
country: France
facility: 14 rue Jean Duplessis
city: Toulouse
country: France
facility: 2 Boulevard Griffoul Dorval
city: Toulouse
country: France
facility: 25 av. Marcel Langer
city: Toulouse
country: France
facility: 28 rue des Arts
city: Toulouse
country: France
facility: 28, rue des Arts
city: Toulouse
country: France
facility: 40, bouleard des Récollets
city: Toulouse
country: France
facility: 7 avenue Frizac
city: Toulouse
country: France
facility: 12 rue Jean Poncelet
city: Toulouse
country: France
facility: 150 avenue Jean Chaubet
city: Toulouse
country: France
facility: 23, rue Limayrac
city: Toulouse
country: France
facility: 24 av. du Cimetiere
city: Toulouse
country: France
facility: 44 av. Leon Blum
city: Toulouse
country: France
facility: 53 r Du Faubourg Bonnefoy
city: Toulouse
country: France
facility: 7 pl Commerciale Jolimont
city: Toulouse
country: France
facility: 7 rue Raymond Boulogne Batiment C- apt 23
city: Tours
country: France
facility: 1 et 3 rue Maryse Bastié
city: Tours
country: France
facility: 1, rue Maryse Bartié
city: Tours
country: France
facility: 11 rue de Clocheville
city: Tours
country: France
facility: 15 rue Jacques Marie Rouge
city: Tours
country: France
facility: 2 rue du Plat d'Etain
city: Tours
country: France
facility: 26 rue Boisdenier
city: Tours
country: France
facility: 29 Bis rue Roger Salengro
city: Tours
country: France
facility: 3 rue Victor Hugo
city: Tours
country: France
facility: 31, rue Léon Boyer
city: Tours
country: France
facility: 63 rue Léon Boyer
city: Tours
country: France
facility: 8 rue de Montbazon
city: Tours
country: France
facility: 89 rue Jean-Jacques Noirmant
city: Tours
country: France
facility: 110 rue de Jemmapes
city: Treviere
country: France
facility: 5 rue de la Halle
city: Tullins
country: France
facility: 26 rue Victor Hugo
city: Uchaud
country: France
facility: 14 Place de l'Eglise
city: Uzes
country: France
facility: Avenue Georges Chauvin
city: Uzes
country: France
facility: Batiment Le Sirius place des Cordeliers
city: Uzes
country: France
facility: Hotel des Cordeliers
city: Uzes
country: France
facility: Hôtel les Cordeliers place des Cordeliers
city: Uzes
country: France
facility: Maison de retraite publique Centre de Memoire Route de Nimes
city: Uzes
country: France
facility: Hotel les Cordeliers place des Cordeliers
city: Vailhauques
country: France
facility: route de Montpellier
city: Valenciennes
country: France
facility: 16 rue Anatole France
city: Valenciennes
country: France
facility: Res. Saly-2 rue S. Lebourg
city: Valras Plage
country: France
facility: 11, Boulevard de la République
city: Vandoeuvre Les Nancy
country: France
facility: 23 Bd de l'Europe
city: Varces
country: France
facility: 12 Place de la République
city: Vauvert
country: France
facility: Le Mistral II
city: Vayres
country: France
facility: 5 avenue de Libourne
city: Venerque
country: France
facility: 12 lotissement Figeac
city: Verneuil sur Avre
country: France
facility: 41 rue de la Pomme d'Or
city: Verny
country: France
facility: 3 Rue Fontaine
city: Vers-Pont-du-Gard
country: France
facility: Rue de la Poste
city: Versailles
country: France
facility: 18 rue de Noailles
city: Vertou
country: France
facility: 57 rue Charles Lecour
city: Vertou
country: France
facility: 7 rue Mortaliere
city: Vezins
country: France
facility: 4 rue du Chapelet
city: Vicherey
country: France
facility: 15 rue du Jard
city: Vieillevigne
country: France
facility: 5 rue des Halles
city: Vieux
country: France
facility: 200 rue Jean Jaures
city: Vihiers
country: France
facility: 4 Rue Beaurepaire
city: Villejuif
country: France
facility: 145 rue de Chevilly
city: Villemomble
country: France
facility: 1 bis avenue Outrebon
city: Villenave D'ornon
country: France
facility: 8 Av G. Clémenceau
city: Villenave D'ornon
country: France
facility: 8 Av. du Gal Clémenceau
city: Villenave D'ornon
country: France
facility: Centre Commercial Chamboparc
city: Villeneuve Tolosane
country: France
facility: 1 Rue René Cassin
city: Villeneuve-les-Maguelonne
country: France
facility: 164 boulevard des Fontaines
city: Villerupt
country: France
facility: 22, rue du Maréchal Foche
city: Villette D'Anthon
country: France
facility: 1, rue des Charmes
city: Villeveque
country: France
facility: 10 Chemin Vignes d'Oule
city: Villey-Saint-Etienne
country: France
facility: 88 rue Liverdun
city: Vinay
country: France
facility: Rue du 8 Mai 1945
city: Vincennes
country: France
facility: 3 avenue Segond
city: Vincennes
country: France
facility: 56, avenue de Paris
city: Voiron
country: France
facility: 11 rue du Faton
city: Vourey
country: France
facility: 15 route de la Gare
city: Vue
country: France
facility: 9, place Sainte Anne
city: Vue
country: France
facility: 85 rue Jean Jaurès
city: Wattignies
country: France
facility: 64 avenue du 14 Juillet
city: Wattrelos
country: France
facility: Maison Medicale Bichat
Study officials:
affiliation: Ipsen
name: Ipsen Medical Director
role: STUDY_DIRECTOR
References:
citation: Vellas B, Coley N, Ousset PJ, Berrut G, Dartigues JF, Dubois B, Grandjean H, Pasquier F, Piette F, Robert P, Touchon J, Garnier P, Mathiex-Fortunet H, Andrieu S; GuidAge Study Group. Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial. Lancet Neurol. 2012 Oct;11(10):851-9. doi: 10.1016/S1474-4422(12)70206-5. Epub 2012 Sep 6.