Clinical trial NCT04553302: Comparison of Hand Functions and Wrist Proprioception in Patients With and Without Psoriatic Arthritis
Official title: Comparison of Hand Functions and Wrist Proprioception in Patients With and Without Psoriatic Arthritis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Psoriatic Arthritis
Keywords: Psoriatic Arthritis, Hand Function, Wrist Proprioception.
Lead sponsor: Izmir Katip Celebi University
Sponsor class: OTHER
First posted: 2020-09-17
Enrollment: 54
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 54 participants

* 18 of them PsA
* 18 of them RA
* 18 of them asymptomatic healthy group

Brief summary: The purpose of this study is to assess hand functions and wrist joint position sense in patients with and without PsA.

Detailed description: In this study, 54 patients (18 of them RA, 18 of them PsA and, 18 of them asymptomatic healthy group) were included. The patient group was selected from the patients who came to the Izmir Katip Celebi University Ataturk Training and Research Hospital Rheumatology Outpatient Clinic for routine control.

Participants were matched according to age and gender. It was recorded demographic and clinical data.

Grip and pinch strengths were evaluated within the scope of hand function evaluation. Wrist joint position sense was evaluated along with hand functions.

Eligibility criteria: Inclusion Criteria:

* to be diagnosed according to CASPAR or ACR/ EULAR 2010 criteria for patient groups
* taking regular medication for patient groups,
* have complaints related to hand / wrist joints for patients groups,
* have no complaints related to upper extremity for asymptomatic healthy group.
* have any rheumatologic disease and OA diagnosed according to traditional criteria

Exclusion Criteria:

* finger infection and / or finger amputation,
* using orthoses,
* to report a diagnosis of neurological disease,
* to report a history of trauma or surgery involving the upper extremity,
* to report a psychiatric and / or cognitive problem

Primary outcomes:
measure: Grip Strength
timeFrame: Data collection will continue until September 2019. Data analysis and report preparation will be completed by August 2020.
Secondary outcomes:
measure: Two-Point Pinch Strength
timeFrame: Data collection will continue until September 2019. Data analysis and report preparation will be completed by August 2020.
measure: Three-Point Pinch Strength
timeFrame: Data collection will continue until September 2019. Data analysis and report preparation will be completed by August 2020.
measure: Lateral Pinch Strength
timeFrame: Data collection will continue until September 2019. Data analysis and report preparation will be completed by August 2020.
measure: DASH score
timeFrame: Data collection will continue until September 2019. Data analysis and report preparation will be completed by August 2020.
measure: Wrist Joint Position Sense
timeFrame: Data collection will continue until September 2019. Data analysis and report preparation will be completed by August 2020.
Other outcomes:
Locations:
city: Izmir
country: Turkey
facility: Izmir Katip Celebi University Ataturk Research and Training Hospital
state: Izmir/ Cigli
Study officials:
affiliation: İzmir Katip Celebi University, Faculty of Health Sciences
name: İlknur NAZ GÜRŞAN, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: INNES, E. V. Handgrip strength testing: a review of the literature. Australian Occupational Therapy Journal, 1999, 46.3: 120-140.
citation: Mathiowetz V, Weber K, Volland G, Kashman N. Reliability and validity of grip and pinch strength evaluations. J Hand Surg Am. 1984 Mar;9(2):222-6. doi: 10.1016/s0363-5023(84)80146-x.
citation: Hudak PL, Amadio PC, Bombardier C. Development of an upper extremity outcome measure: the DASH (disabilities of the arm, shoulder and hand) [corrected]. The Upper Extremity Collaborative Group (UECG). Am J Ind Med. 1996 Jun;29(6):602-8. doi: 10.1002/(SICI)1097-0274(199606)29:63.0.CO;2-L.
citation: Navsarikar A, Gladman DD, Husted JA, Cook RJ. Validity assessment of the disabilities of arm, shoulder, and hand questionnaire (DASH) for patients with psoriatic arthritis. J Rheumatol. 1999 Oct;26(10):2191-4.
citation: Feced Olmos CM, Alvarez-Calderon O, Hervas Marin D, Ivorra Cortes J, Pujol Marco C, Roman Ivorra JA. Relationship between structural damage with loss of strength and functional disability in psoriatic arthritis patients. Clin Biomech (Bristol). 2019 Aug;68:169-174. doi: 10.1016/j.clinbiomech.2019.06.009. Epub 2019 Jun 11.