Clinical trial NCT06483464: Validation of ACS NSQIP Risk Calculator for Predicting Complications After Thoracic Surgery at University Hospital Basel
Official title: Validation of the ACS NSQIP Risk Calculator as Predictive Tool for Complications After Thoracic Surgery in Consecutive Series of Patients Operated at the Department of Thoracic Surgery University Hospital Basel
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Thoracic
Keywords: Thoracic surgery
Predicting complications
National Surgical Quality Improvement Program of the American College of Surgeons (ACS NSQIP)
Lead sponsor: University Hospital, Basel, Switzerland
Sponsor class: OTHER
First posted: 2024-07-03
Enrollment: 300
Sex: ALL
Minimum age (years): 14
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: A consecutive series of cases of patients who signed the general research consent of the University Hospital Basel and have undergone a thoracic intervention at the University Hospital Basel between 01.05.2021 to 01.03.2022.

Brief summary: This single-center retrospective research project aims to evaluate whether and what is the significance of the National Surgical Quality Improvement Program of the American College of Surgeons (ACS NSQIP) risk score in thoracic surgery at the University Hospital Basel.

Detailed description: Advances in medical and surgical therapies have enabled treatment for polymorbid patients, who often have multiple chronic conditions. This has increased the need to accurately assess the risks of postoperative complications and mortality. Due to their complex health status, these patients are more susceptible to adverse outcomes following surgery, necessitating precise risk prediction to guide clinical decision-making and optimize outcomes.

This single-center retrospective research project compares the preoperative risk assessments by the National Surgical Quality Improvement Program of the American College of Surgeons (ACS NSQIP) risk calculator with actual complications (graded according to the Clavien-Dindo classification) observed in patients who underwent thoracic surgery at the University Hospital Basel between May 1, 2021, and March 1, 2022.

The ACS NSQIP risk calculator, a web-based tool, uses 21 preoperative risk factors to predict 13 perioperative outcomes, including serious complications, infections, and mortality. By evaluating these predictions against real patient outcomes, this research project aims to validate the calculator's accuracy specifically in the context of thoracic surgery.

The results of this research project could optimize patient care by better identifying high-risk patients and improving preoperative preparation.

Eligibility criteria: Inclusion Criteria:

* Patients with signed general research consent
* Patients who underwent surgery in our department for the period from 01.05.2021 to 01.03.2022
* Patients with preoperative ACS NSQIP Risk score

Exclusion Criteria:

* Patients who have clearly stated that they would not agree in providing their clinical data for scientific purposes

Primary outcomes:
measure: Suitability of the ACS NSQIP risk calculator
timeFrame: Up to 30 days after surgery
Secondary outcomes:
Other outcomes:
Locations:
city: Basel
country: Switzerland
facility: Department of Thoracic Surgery, University Hospital of Basel
Study officials:
affiliation: Department of Thoracic Surgery, University Hospital of Basel
name: Nikolay Tsvetkov, MD
role: PRINCIPAL_INVESTIGATOR
References: