Clinical trial NCT04790110: 7 Year Follow up Analysis on the Speed of Progression of Tooth Wear Using 3D Subtraction
Official title: The Progression of Tooth Wear and Possible Risk Factors: a 7 Year Follow up
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Tooth Wear
Reflux Acid
Bruxism
Keywords: Progression of tooth wear
Lead sponsor: Radboud University Medical Center
Sponsor class: OTHER
Collaborators: name: Stichting Bevordering Tandheelkundige Kennis of the Nederlands Tijdschrift voor Tandheelkunde
First posted: 2021-03-10
Enrollment: 55
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The participants in this research will be drawn from the RTWP (Radboud Tooth Wear Project) patient sample which consists of nearly 200 tooth wear patients. Patients are included through dentist referral or of their own volition. Out of this population, 55 patients are managed non-restoratively, because they do not experience problems in regards to their tooth wear, and have no restorative treatment need in their perception

Brief summary: Prospective observational study with 7-year follow up. 55 patients are included with moderate to severe tooth wear, whereby through informed consent the decision was taking to monitor the patients. At the baseline and 1, 3 5, and the 7-year recall digital 3D scans will be made, which will be compared and subtracted.

Detailed description: Prospective observational study with 7-year follow up. 55 patients are included with moderate to severe tooth wear, whereby through informed consent the decision was taking to monitor the patients. At the baseline and the 5-year recall digital 3D scans will be made, which will be compared and subtracted. Per tooth the loss of material is measured in maximum loss in height (µm) and volume (mm3) per year, using best fit alignment and 3D subtraction.

The loss of tooth material will be analyzed using descriptive statistics and possible effects of jaw type, tooth type and cusp type will be analyzed using multi level regression models.

The use of index teeth will be analyzed.

Eligibility criteria: Inclusion Criteria:

* Generalized tooth wear
* A minimum of three posterior teeth (premolars and molars) per quadrant
* A maximum of one edentulous space in need for treatment, with a maximum span of one tooth-width

Exclusion Criteria:

* ASA 4
* Edentulous space has a span exceeding 1 tooth-width, or more than one space
* Functional problems (mouth opening \<5cm, Temporomandibular Dysfunction)
* Severe periodontitis
* Strong gag reflex

Primary outcomes:
measure: degree of dental wear in height
timeFrame: 7 years
Secondary outcomes:
measure: The use of index teeth
timeFrame: 7 years
Other outcomes:
Locations:
city: Nijmegen
country: Netherlands
facility: Radboud University Medical Center
state: Gelderland
Study officials:
References:
citation: Ahmed KE, Whitters J, Ju X, Pierce SG, MacLeod CN, Murray CA. Clinical Monitoring of Tooth Wear Progression in Patients over a Period of One Year Using CAD/CAM. Int J Prosthodont. 2017 Mar/Apr;30(2):153-155. doi: 10.11607/ijp.4990.
citation: Loomans B, Opdam N, Attin T, Bartlett D, Edelhoff D, Frankenberger R, Benic G, Ramseyer S, Wetselaar P, Sterenborg B, Hickel R, Pallesen U, Mehta S, Banerji S, Lussi A, Wilson N. Severe Tooth Wear: European Consensus Statement on Management Guidelines. J Adhes Dent. 2017;19(2):111-119. doi: 10.3290/j.jad.a38102.