Clinical trial NCT01057823: Understanding Sleep in Hospitalized Older Patients
Official title: Environment and Perceived Control: Improving Sleep in Hospitalized Older Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Sleep Deprivation
Sleep Fragmentation
Keywords: aged
sleep deprivation
actigraphy
ambulatory monitoring
Lead sponsor: University of Chicago
Sponsor class: OTHER
Collaborators: name: National Institute on Aging (NIA)
First posted: 2010-01-27
Enrollment: 771
Sex: ALL
Minimum age (years): 50
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Community-dwelling ambulatory patients age 50 or above hospitalized on the University of Chicago general medicine service.

Brief summary: The overall goal of this research is to elucidate how environmental, healthcare, and patient-level factors and patients' level of perceived control impact sleep duration and quality in hospitalized older patients and to assess whether better in-hospital sleep is associated with improved physical activity and health outcomes.

We hypothesize that environment, healthcare disruptions and patient symptoms will be significantly associated with objective and subjective sleep duration and sleep quality in hospitalized older patients.

We also hypothesize that a high level of perceived control will be associated with improved sleep duration and quality in hospitalized older patients.

We further hypothesize that shorter sleep duration and quality in hospitalized older adults will be associated with adverse health outcomes, namely higher blood pressure and blood sugar.

Detailed description: This research can lead to a better understanding of the effects of inpatient sleep on health outcomes for hospitalized older patients and can help inform the design and evaluation of interventions designed to improve sleep in hospitalized older patients. This work can also form the foundation for understanding the longer term health effects of inpatient sleep loss for older patients that are potentially modifiable.

Eligibility criteria: Inclusion Criteria:

* Age 50 or above
* Hospitalized on General Medicine service
* Ambulatory
* Community Dwelling
* MMSE \>17

Exclusion Criteria:

* transfer from the ICU or another hospital
* cognitively impaired
* not ambulatory
* residents of a nursing home or skilled nursing facility
* on bedrest
* documented sleep disorder in their medical history

Primary outcomes:
measure: Sleep will be measured using subjective reports (Karolinska Sleep Diary on Daily Sleep Assessment).
timeFrame: January 2010-January 2015
Secondary outcomes:
measure: Sleep will also be measured objectively using actigraphy.
timeFrame: January 2010-January 2015
Other outcomes:
Locations:
city: Chicago
country: United States
facility: The University of Chicago Medical Center
state: Illinois
Study officials:
affiliation: University of Chicago
name: Vineet M Arora, MD, MA
role: PRINCIPAL_INVESTIGATOR
References:
citation: Arora VM, Chang KL, Fazal AZ, Staisiunas PG, Meltzer DO, Zee PC, Knutson KL, Van Cauter E. Objective sleep duration and quality in hospitalized older adults: associations with blood pressure and mood. J Am Geriatr Soc. 2011 Nov;59(11):2185-6. doi: 10.1111/j.1532-5415.2011.03644.x. No abstract available.
citation: Yoder JC, Staisiunas PG, Meltzer DO, Knutson KL, Arora VM. Noise and sleep among adult medical inpatients: far from a quiet night. Arch Intern Med. 2012 Jan 9;172(1):68-70. doi: 10.1001/archinternmed.2011.603. No abstract available.
citation: Adachi M, Staisiunas PG, Knutson KL, Beveridge C, Meltzer DO, Arora VM. Perceived control and sleep in hospitalized older adults: a sound hypothesis? J Hosp Med. 2013 Apr;8(4):184-90. doi: 10.1002/jhm.2027. Epub 2013 Mar 18.
citation: DePietro RH, Knutson KL, Spampinato L, Anderson SL, Meltzer DO, Van Cauter E, Arora VM. Association Between Inpatient Sleep Loss and Hyperglycemia of Hospitalization. Diabetes Care. 2017 Feb;40(2):188-193. doi: 10.2337/dc16-1683. Epub 2016 Nov 30.