Clinical trial NCT03620864: Neurodynamic Intervention for Lumbar Radiculopathy
Official title: Motor Control Exercises and Neurodynamic Intervention for Lumbar Radiculopathy: A Randomized Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Lumbar Radiculopathy
Lead sponsor: Universidad Rey Juan Carlos
Sponsor class: OTHER
First posted: 2018-08-08
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Low back pain (LBP) is a common condition and has a significant impact on the individual in terms of pain and disability. Lumbar radiculopathy occurs often with LBP and may be the result of a lumbar herniated disc which will irritate a lumbar nerve trunk resulting in intraneural inflammation. There is evidence supporting the use of manual therapies of lumbar radiculopathy. One potential manual therapy is neurodynamic mobilization technique. No scientific evidence, based on a RCT, exists that this particular approach is beneficial for individuals with LBP and lumbar radiculopathy


Eligibility criteria: Inclusion Criteria:

* Subjects with a confirmed (via MRI) disc herniation at between L4 and S1 level;
* Subjects exhibiting lumbar radiating pain in the lower extremity for at least 3 months
* Subjects with a positive straight leg raise with symptoms reproduction

Exclusion Criteria:

* indication for surgical intervention;
* had a confirmed disc herniation at other lumbar levels;
* have had any other spinal conditions such as spinal tumors or spondylolisthesis;
* had received treatment for this condition by a physical therapist the previous 6 month;
* pregnancy

Primary outcomes:
measure: Changes in Lower Extremity Pain Intensity
timeFrame: Baseline, after 4 treatment sessions, after 8 treatment sessions,and 2 months after last treatment session
Secondary outcomes:
measure: Changes in Neuropathic Mechanism Consideration
timeFrame: Baseline, after 4 treatment sessions, after 8 treatment sessions,and 2 months after last treatment session
measure: Changes in Related-Disability
timeFrame: Baseline, after 4 treatment sessions, after 8 treatment sessions,and 2 months after last treatment session
measure: Changes in Mechanical Sensitivity of the Sciatic Nerve
timeFrame: Baseline, after 4 treatment sessions, after 8 treatment sessions,and 2 months after last treatment session
measure: Changes in Pressure Pain Thresholds
timeFrame: Baseline, after 4 treatment sessions, after 8 treatment sessions,and 2 months after last treatment session
Other outcomes:
Locations:
city: Alcorcon
country: Spain
facility: Universidad Rey Juan Carlos
state: Madrid
Study officials:
References:
citation: Plaza-Manzano G, Cancela-Cilleruelo I, Fernandez-de-Las-Penas C, Cleland JA, Arias-Buria JL, Thoomes-de-Graaf M, Ortega-Santiago R. Effects of Adding a Neurodynamic Mobilization to Motor Control Training in Patients With Lumbar Radiculopathy Due to Disc Herniation: A Randomized Clinical Trial. Am J Phys Med Rehabil. 2020 Feb;99(2):124-132. doi: 10.1097/PHM.0000000000001295.