Clinical trial NCT01663402: ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab
Official title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Atherosclerotic Cardiovascular Disease
Lead sponsor: Sanofi
Sponsor class: INDUSTRY
Collaborators: name: Regeneron Pharmaceuticals
First posted: 2012-08-13
Enrollment: 18924
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Primary Objective:

To compare the effect of alirocumab with placebo on the occurrence of cardiovascular (CV) events (composite endpoint of coronary heart disease (CHD) death, non-fatal myocardial infarction (MI), fatal and non-fatal ischemic stroke, unstable angina (UA) requiring hospitalization) in participants who experienced an acute coronary syndrome (ACS) event 4 to 52 weeks prior to randomization and were treated with evidence-based medical and dietary management of dyslipidemia.

Secondary Objectives:

* To evaluate the effect of alirocumab on secondary endpoints (any CHD event , major CHD event, any CV event, composite of all cause mortality/non-fatal MI/non-fatal ischemic stroke, CHD deaths, CV deaths, all cause mortality).
* To evaluate the safety and tolerability of alirocumab.
* To evaluate the effect of alirocumab on lipid parameters.

Detailed description: 18924 number of participants aged \>= 40 years old were randomized in the study.

Eligibility criteria: Inclusion criteria :

Recently (\< 52 weeks) hospitalized for ACS.

Exclusion criteria:

* Age \< 40 years.
* ACS event occurring more than 52 weeks prior to randomization visit.
* LDL-C likely to be \<70 mg/dL (\<1.81 mmo/L), and apolipoprotein B (ApoB) \<80 mg/dL (\<0.8 g/L), and non - high-density lipoprotein cholesterol (HDL-C) \<100 mg/dL (\<2.59 mmol/L) with evidence-based medical and dietary management of dyslipidemia.

The above information is not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.

Primary outcomes:
measure: Time to First Occurrence of Major Adverse Cardiovascular Event (MACE); Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
Secondary outcomes:
measure: Time to First Occurrence of Any Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Any Major Coronary Heart Disease Event; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Any Cardiovascular Event; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of All-Cause Mortality, Non-Fatal Myocardial Infarction, Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to Coronary Heart Disease Death; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to Cardiovascular Death; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to All-Cause Death; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Any Non-Fatal Myocardial Infarction; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Fatal or Any Non-Fatal Ischemic Stroke; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Any Unstable Angina Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Any Ischemia-Driven Coronary Revascularization Procedure; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
measure: Time to First Occurrence of Any Congestive Heart Failure (CHF) Requiring Hospitalization; Percentage of Observed Participants With Outcome Measure Events During the Study
timeFrame: From randomization up to 64 months
Other outcomes:
measure: Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: ITT Analysis
timeFrame: Baseline, Months 4, 12 and 48
measure: Percent Change From Baseline in Calculated LDL-C at Months 4, 12, and 48: On-Treatment Analysis
timeFrame: Baseline, Months 4, 12 and 48
Locations:
city: Birmingham
country: United States
facility: Investigational Site Number 840163
state: Alabama
city: Birmingham
country: United States
facility: Investigational Site Number 840060
state: Alabama
city: Huntsville
country: United States
facility: Investigational Site Number 840117
state: Alabama
city: Huntsville
country: United States
facility: Investigational Site Number 840192
state: Alabama
city: Mobile
country: United States
facility: Investigational Site Number 840121
state: Alabama
city: Mobile
country: United States
facility: Investigational Site Number 840319
state: Alabama
city: Atlantis
country: United States
facility: Investigational Site Number 840332
state: Arizona
city: Newport Beach
country: United States
facility: Investigational Site Number 840320
state: Arizona
city: Tucson
country: United States
facility: Investigational Site Number 840103
state: Arizona
city: Tucson
country: United States
facility: Investigational Site Number 840084
state: Arizona
city: Banning
country: United States
facility: Investigational Site Number 840139
state: California
city: Beverly Hills
country: United States
facility: Investigational Site Number 840286
state: California
city: Beverly Hills
country: United States
facility: Investigational Site Number 840246
state: California
city: Beverly Hills
country: United States
facility: Investigational Site Number 840353
state: California
city: Carmichael
country: United States
facility: Investigational Site Number 840341
state: California
city: Chula Vista
country: United States
facility: Investigational Site Number 840299
state: California
city: Fresno
country: United States
facility: Investigational Site Number 840164
state: California
city: Fullerton
country: United States
facility: Investigational Site Number 840076
state: California
city: Huntington Beach
country: United States
facility: Investigational Site Number 840073
state: California
city: La Jolla
country: United States
facility: Investigational Site Number 840092
state: California
city: Long Beach
country: United States
facility: Investigational Site Number 840208
state: California
city: Long Beach
country: United States
facility: Investigational Site Number 840068
state: California
city: Los Alamitos
country: United States
facility: Investigational Site Number 840269
state: California
city: Los Angeles
country: United States
facility: Investigational Site Number 840009
state: California
city: Los Angeles
country: United States
facility: Investigational Site Number 840282
state: California
city: Mission Viejo
country: United States
facility: Investigational Site Number 840019
state: California
city: Moreno Valley
country: United States
facility: Investigational Site Number 840336
state: California
city: Northridge
country: United States
facility: Investigational Site Number 840124
state: California
city: Pasadena
country: United States
facility: Investigational Site Number 840251
state: California
city: Pasadena
country: United States
facility: Investigational Site Number 840289
state: California
city: Port Hueneme
country: United States
facility: Investigational Site Number 840312
state: California
city: San Diego
country: United States
facility: Investigational Site Number 840261
state: California
city: San Diego
country: United States
facility: Investigational Site Number 840310
state: California
city: San Diego
country: United States
facility: Investigational Site Number 840024
state: California
city: Santa Ana
country: United States
facility: Investigational Site Number 840071
state: California
city: Santa Rosa
country: United States
facility: Investigational Site Number 840236
state: California
city: Torrance
country: United States
facility: Investigational Site Number 840012
state: California
city: Aurora
country: United States
facility: Investigational Site Number 840096
state: Colorado
city: Colorado Springs
country: United States
facility: Investigational Site Number 840037
state: Colorado
city: Denver
country: United States
facility: Investigational Site Number 840189
state: Colorado
city: Bridgeport
country: United States
facility: Investigational Site Number 840122
state: Connecticut
city: Guilford
country: United States
facility: Investigational Site Number 840219
state: Connecticut
city: Altamonte Springs
country: United States
facility: Investigational Site Number 840347
state: Florida
city: Clearwater
country: United States
facility: Investigational Site Number 840066
state: Florida
city: Daytona Beach
country: United States
facility: Investigational Site Number 840079
state: Florida
city: Daytona Beach
country: United States
facility: Investigational Site Number 840051
state: Florida
city: Delray Beach
country: United States
facility: Investigational Site Number 840368
state: Florida
city: Fort Lauderdale
country: United States
facility: Investigational Site Number 840242
state: Florida
city: Gainesville
country: United States
facility: Investigational Site Number 840134
state: Florida
city: Hollywood
country: United States
facility: Investigational Site Number 840327
state: Florida
city: Hudson
country: United States
facility: Investigational Site Number 840153
state: Florida
city: Hudson
country: United States
facility: Investigational Site Number 840105
state: Florida
city: Jacksonville
country: United States
facility: Investigational Site Number 840253
state: Florida
city: Jacksonville
country: United States
facility: Investigational Site Number 840141
state: Florida
city: Jacksonville
country: United States
facility: Investigational Site Number 840042
state: Florida
city: Jacksonville
country: United States
facility: Investigational Site Number 840206
state: Florida
city: Jacksonville
country: United States
facility: Investigational Site Number 840063
state: Florida
city: Jupiter
country: United States
facility: Investigational Site Number 840002
state: Florida
city: Largo
country: United States
facility: Investigational Site Number 840119
state: Florida
city: Miami Beach
country: United States
facility: Investigational Site Number 840241
state: Florida
city: Mount Clemens
country: United States
facility: Investigational Site Number 840210
state: Florida
city: New Port Richey
country: United States
facility: Investigational Site Number 840366
state: Florida
city: Palm Beach Gardens
country: United States
facility: Investigational Site Number 840311
state: Florida
city: Palm Harbor
country: United States
facility: Investigational Site Number 840280
state: Florida
city: Panama City
country: United States
facility: Investigational Site Number 840054
state: Florida
city: Pembroke Pines
country: United States
facility: Investigational Site Number 840239
state: Florida
city: Pensacola
country: United States
facility: Investigational Site Number 840044
state: Florida
city: Plantation
country: United States
facility: Investigational Site Number 840367
state: Florida
city: Safety Harbor
country: United States
facility: Investigational Site Number 840132
state: Florida
city: Safety Harbor
country: United States
facility: Investigational Site Number 840061
state: Florida
city: Sarasota
country: United States
facility: Investigational Site Number 840247
state: Florida
city: Tampa
country: United States
facility: Investigational Site Number 840264
state: Florida
city: Tampa
country: United States
facility: Investigational Site Number 840082
state: Florida
city: Trinity
country: United States
facility: Investigational Site Number 840213
state: Florida
city: Wellington
country: United States
facility: Investigational Site Number 840165
state: Florida
city: West Palm Beach
country: United States
facility: Investigational Site Number 840323
state: Florida
city: Atlanta
country: United States
facility: Investigational Site Number 840075
state: Georgia
city: Augusta
country: United States
facility: Investigational Site Number 840176
state: Georgia
city: Covington
country: United States
facility: Investigational Site Number 840048
state: Georgia
city: Cumming
country: United States
facility: Investigational Site Number 840065
state: Georgia
city: Thomasville
country: United States
facility: Investigational Site Number 840356
state: Georgia
city: Tucker
country: United States
facility: Investigational Site Number 840114
state: Georgia
city: Idaho Falls
country: United States
facility: Investigational Site Number 840211
state: Idaho
city: Arlington Heights
country: United States
facility: Investigational Site Number 840237
state: Illinois
city: Chicago
country: United States
facility: Investigational Site Number 840292
state: Illinois
city: Harvey
country: United States
facility: Investigational Site Number 840146
state: Illinois
city: Joliet
country: United States
facility: Investigational Site Number 840340
state: Illinois
city: Peoria
country: United States
facility: Investigational Site Number 840196
state: Illinois
city: Rock Island
country: United States
facility: Investigational Site Number 840081
state: Illinois
city: Rock Island
country: United States
facility: Investigational Site Number 840090
state: Illinois
city: Elkhart
country: United States
facility: Investigational Site Number 840358
state: Indiana
city: Hammond
country: United States
facility: Investigational Site Number 840036
state: Indiana
city: Indianapolis
country: United States
facility: Investigational Site Number 840026
state: Indiana
city: Muncie
country: United States
facility: Investigational Site Number 840102
state: Indiana
city: South Bend
country: United States
facility: Investigational Site Number 840145
state: Indiana
city: Ames
country: United States
facility: Investigational Site Number 840154
state: Iowa
city: Iowa City
country: United States
facility: Investigational Site Number 840345
state: Iowa
city: West Des Moines
country: United States
facility: Investigational Site Number 840283
state: Iowa
city: Kansas City
country: United States
facility: Investigational Site Number 840335
state: Kansas
city: Kansas City
country: United States
facility: Investigational Site Number 840089
state: Kansas
city: Kansas City
country: United States
facility: Investigational Site Number 840218
state: Kansas
city: Overland Park
country: United States
facility: Investigational Site Number 840140
state: Kansas
city: Lexington
country: United States
facility: Investigational Site Number 840030
state: Kentucky
city: Louisville
country: United States
facility: Investigational Site Number 840023
state: Kentucky
city: Louisville
country: United States
facility: Investigational Site Number 840007
state: Kentucky
city: Owensboro
country: United States
facility: Investigational Site Number 840279
state: Kentucky
city: Pikeville
country: United States
facility: Investigational Site Number 840308
state: Kentucky
city: Saint Paul
country: United States
facility: Investigational Site Number 840181
state: Kentucky
city: Alexandria
country: United States
facility: Investigational Site Number 840254
state: Louisiana
city: Lafayette
country: United States
facility: Investigational Site Number 840344
state: Louisiana
city: Lake Charles
country: United States
facility: Investigational Site Number 840187
state: Louisiana
city: Minden
country: United States
facility: Investigational Site Number 840291
state: Louisiana
city: New Orleans
country: United States
facility: Investigational Site Number 840278
state: Louisiana
city: Shreveport
country: United States
facility: Investigational Site Number 840290
state: Louisiana
city: Auburn
country: United States
facility: Investigational Site Number 840142
state: Maine
city: Auburn
country: United States
facility: Investigational Site Number 840148
state: Maine
city: Bangor
country: United States
facility: Investigational Site Number 840097
state: Maine
city: Framingham
country: United States
facility: Investigational Site Number 840234
state: Maine
city: Scarborough
country: United States
facility: Investigational Site Number 840276
state: Maine
city: Annapolis
country: United States
facility: Investigational Site Number 840351
state: Maryland
city: Beltsville
country: United States
facility: Investigational Site Number 840072
state: Maryland
city: Bethesda
country: United States
facility: Investigational Site Number 840193
state: Maryland
city: Columbia
country: United States
facility: Investigational Site Number 840200
state: Maryland
city: Rockville
country: United States
facility: Investigational Site Number 840349
state: Maryland
city: Winfield
country: United States
facility: Investigational Site Number 840111
state: Maryland
city: Boston
country: United States
facility: Investigational Site Number 840056
state: Massachusetts
city: Flint
country: United States
facility: Investigational Site Number 840144
state: Michigan
city: Grandville
country: United States
facility: Investigational Site Number 840365
state: Michigan
city: Kalamazoo
country: United States
facility: Investigational Site Number 840093
state: Michigan
city: Lansing
country: United States
facility: Investigational Site Number 840198
state: Michigan
city: Rochester Hills
country: United States
facility: Investigational Site Number 840087
state: Michigan
city: Springfield
country: United States
facility: Investigational Site Number 840004
state: Michigan
city: Springfield
country: United States
facility: Investigational Site Number 840267
state: Michigan
city: Ypsilanti
country: United States
facility: Investigational Site Number 840035
state: Michigan
city: Duluth
country: United States
facility: Investigational Site Number 840199
state: Minnesota
city: Edina
country: United States
facility: Investigational Site Number 840116
state: Minnesota
city: Minneapolis
country: United States
facility: Investigational Site Number 840281
state: Minnesota
city: Saint Cloud
country: United States
facility: Investigational Site Number 840094
state: Minnesota
city: Saint Paul
country: United States
facility: Investigational Site Number 840324
state: Minnesota
city: Columbia
country: United States
facility: Investigational Site Number 840046
state: Missouri
city: Independence
country: United States
facility: Investigational Site Number 840180
state: Missouri
city: Little Rock
country: United States
facility: Investigational Site Number 840274
state: Missouri
city: Marquette
country: United States
facility: Investigational Site Number 840013
state: Missouri
city: Overland
country: United States
facility: Investigational Site Number 840179
state: Missouri
city: Saint Louis
country: United States
facility: Investigational Site Number 840228
state: Missouri
city: Saint Louis
country: United States
facility: Investigational Site Number 840233
state: Missouri
city: Saint Louis
country: United States
facility: Investigational Site Number 840235
state: Missouri
city: Saint Louis
country: United States
facility: Investigational Site Number 840175
state: Missouri
city: Saint Louis
country: United States
facility: Investigational Site Number 840125
state: Missouri
city: Saint Louis
country: United States
facility: Investigational Site Number 840168
state: Missouri
city: Kalispell
country: United States
facility: Investigational Site Number 840032
state: Montana
city: Grand Island
country: United States
facility: Investigational Site Number 840033
state: Nebraska
city: Omaha
country: United States
facility: Investigational Site Number 840015
state: Nebraska
city: Omaha
country: United States
facility: Investigational Site Number 840021
state: Nebraska
city: Omaha
country: United States
facility: Investigational Site Number 840001
state: Nebraska
city: Las Vegas
country: United States
facility: Investigational Site Number 840221
state: Nevada
city: Nashua
country: United States
facility: Investigational Site Number 840062
state: New Hampshire
city: Bridgewater
country: United States
facility: Investigational Site Number 840077
state: New Jersey
city: Bridgewater
country: United States
facility: Investigational Site Number 840173
state: New Jersey
city: Flemington
country: United States
facility: Investigational Site Number 840127
state: New Jersey
city: Hackensack
country: United States
facility: Investigational Site Number 840359
state: New Jersey
city: Moorestown
country: United States
facility: Investigational Site Number 840348
state: New Jersey
city: New Brunswick
country: United States
facility: Investigational Site Number 840128
state: New Jersey
city: Pomona
country: United States
facility: Investigational Site Number 840167
state: New Jersey
city: Ridgewood
country: United States
facility: Investigational Site Number 840067
state: New Jersey
city: Somerset
country: United States
facility: Investigational Site Number 840250
state: New Jersey
city: Voorhees
country: United States
facility: Investigational Site Number 840277
state: New Jersey
city: Westwood
country: United States
facility: Investigational Site Number 840083
state: New Jersey
city: Bronx
country: United States
facility: Investigational Site Number 840222
state: New York
city: Buffalo
country: United States
facility: Investigational Site Number 840322
state: New York
city: New York
country: United States
facility: Investigational Site Number 840248
state: New York
city: New York
country: United States
facility: Investigational Site Number 840371
state: New York
city: Newburgh
country: United States
facility: Investigational Site Number 840333
state: New York
city: Poughkeepsie
country: United States
facility: Investigational Site Number 840017
state: New York
city: Valhalla
country: United States
facility: Investigational Site Number 840166
state: New York
city: Williamsville
country: United States
facility: Investigational Site Number 840354
state: New York
city: Elizabeth City
country: United States
facility: Investigational Site Number 840070
state: North Carolina
city: Greenville
country: United States
facility: Investigational Site Number 840303
state: North Carolina
city: Greenville
country: United States
facility: Investigational Site Number 840182
state: North Carolina
city: Raleigh
country: United States
facility: Investigational Site Number 840243
state: North Carolina
city: Raleigh
country: United States
facility: Investigational Site Number 840342
state: North Carolina
city: Rocky Mount
country: United States
facility: Investigational Site Number 840293
state: North Carolina
city: Statesville
country: United States
facility: Investigational Site Number 840088
state: North Carolina
city: Wilmington
country: United States
facility: Investigational Site Number 840052
state: North Carolina
city: Baltimore
country: United States
facility: Investigational Site Number 840306
state: North Dakota
city: Fargo
country: United States
facility: Investigational Site Number 840214
state: North Dakota
city: Minot
country: United States
facility: Investigational Site Number 840095
state: North Dakota
city: Mountain Lakes
country: United States
facility: Investigational Site Number 840257
state: North Dakota
city: Akron
country: United States
facility: Investigational Site Number 840364
state: Ohio
city: Cincinnati
country: United States
facility: Investigational Site Number 840131
state: Ohio
city: Columbus
country: United States
facility: Investigational Site Number 840045
state: Ohio
city: Columbus
country: United States
facility: Investigational Site Number 840265
state: Ohio
city: Lorain
country: United States
facility: Investigational Site Number 840113
state: Ohio
city: Lorain
country: United States
facility: Investigational Site Number 840115
state: Ohio
city: Maumee
country: United States
facility: Investigational Site Number 840309
state: Ohio
city: Springfield
country: United States
facility: Investigational Site Number 840297
state: Ohio
city: Toledo
country: United States
facility: Investigational Site Number 840172
state: Ohio
city: Youngstown
country: United States
facility: Investigational Site Number 840263
state: Ohio
city: Oklahoma City
country: United States
facility: Investigational Site Number 840334
state: Oklahoma
city: Oklahoma City
country: United States
facility: Investigational Site Number 840337
state: Oklahoma
city: Tulsa
country: United States
facility: Investigational Site Number 840018
state: Oklahoma
city: Portland
country: United States
facility: Investigational Site Number 840184
state: Oregon
city: Allentown
country: United States
facility: Investigational Site Number 840133
state: Pennsylvania
city: Beaver
country: United States
facility: Investigational Site Number 840104
state: Pennsylvania
city: Camp Hill
country: United States
facility: Investigational Site Number 840170
state: Pennsylvania
city: Doylestown
country: United States
facility: Investigational Site Number 840020
state: Pennsylvania
city: Erie
country: United States
facility: Investigational Site Number 840016
state: Pennsylvania
city: Goodyear
country: United States
facility: Investigational Site Number 840329
state: Pennsylvania
city: Knoxville
country: United States
facility: Investigational Site Number 840126
state: Pennsylvania
city: Lancaster
country: United States
facility: Investigational Site Number 840249
state: Pennsylvania
city: Lancaster
country: United States
facility: Investigational Site Number 840150
state: Pennsylvania
city: Philadelphia
country: United States
facility: Investigational Site Number 840231
state: Pennsylvania
city: Philadelphia
country: United States
facility: Investigational Site Number 840339
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Investigational Site Number 840230
state: Pennsylvania
city: Sayre
country: United States
facility: Investigational Site Number 840028
state: Pennsylvania
city: Scranton
country: United States
facility: Investigational Site Number 840069
state: Pennsylvania
city: Scranton
country: United States
facility: Investigational Site Number 840316
state: Pennsylvania
city: Seven Fields
country: United States
facility: Investigational Site Number 840273
state: Pennsylvania
city: Washington
country: United States
facility: Investigational Site Number 840227
state: Pennsylvania
city: Pawtucket
country: United States
facility: Investigational Site Number 840129
state: Rhode Island
city: Anderson
country: United States
facility: Investigational Site Number 840118
state: South Carolina
city: Greenwood
country: United States
facility: Investigational Site Number 840190
state: South Carolina
city: Lancaster
country: United States
facility: Investigational Site Number 840360
state: South Carolina
city: Myrtle Beach
country: United States
facility: Investigational Site Number 840314
state: South Carolina
city: Rapid City
country: United States
facility: Investigational Site Number 840008
state: South Dakota
city: Chattanooga
country: United States
facility: Investigational Site Number 840285
state: Tennessee
city: Jackson
country: United States
facility: Investigational Site Number 840287
state: Tennessee
city: Johnson City
country: United States
facility: Investigational Site Number 840040
state: Tennessee
city: Knoxville
country: United States
facility: Investigational Site Number 840238
state: Tennessee
city: Oak Ridge
country: United States
facility: Investigational Site Number 840195
state: Tennessee
city: Amarillo
country: United States
facility: Investigational Site Number 840205
state: Texas
city: Amarillo
country: United States
facility: Investigational Site Number 840352
state: Texas
city: Austin
country: United States
facility: Investigational Site Number 840135
state: Texas
city: Dallas
country: United States
facility: Investigational Site Number 840301
state: Texas
city: Dallas
country: United States
facility: Investigational Site Number 840152
state: Texas
city: Dallas
country: United States
facility: Investigational Site Number 840157
state: Texas
city: Fort Worth
country: United States
facility: Investigational Site Number 840229
state: Texas
city: Fort Worth
country: United States
facility: Investigational Site Number 840120
state: Texas
city: Fort Worth
country: United States
facility: Investigational Site Number 840258
state: Texas
city: Kingwood
country: United States
facility: Investigational Site Number 840136
state: Texas
city: Lubbock
country: United States
facility: Investigational Site Number 840027
state: Texas
city: Lufkin
country: United States
facility: Investigational Site Number 840202
state: Texas
city: Odessa
country: United States
facility: Investigational Site Number 840270
state: Texas
city: San Antonio
country: United States
facility: Investigational Site Number 840162
state: Texas
city: San Antonio
country: United States
facility: Investigational Site Number 840232
state: Texas
city: Schertz
country: United States
facility: Investigational Site Number 840328
state: Texas
city: Tyler
country: United States
facility: Investigational Site Number 840158
state: Texas
city: Victoria
country: United States
facility: Investigational Site Number 840318
state: Texas
city: Wichita Falls
country: United States
facility: Investigational Site Number 840245
state: Texas
city: Orem
country: United States
facility: Investigational Site Number 840256
state: Utah
city: Salt Lake City
country: United States
facility: Investigational Site Number 840296
state: Utah
city: Burlington
country: United States
facility: Investigational Site Number 840053
state: Vermont
city: Charlottesville
country: United States
facility: Investigational Site Number 840049
state: Virginia
city: Charlottesville
country: United States
facility: Investigational Site Number 840260
state: Virginia
city: Harrisonburg
country: United States
facility: Investigational Site Number 840350
state: Virginia
city: Leesburg
country: United States
facility: Investigational Site Number 840215
state: Virginia
city: Lynchburg
country: United States
facility: Investigational Site Number 840010
state: Virginia
city: Manassas
country: United States
facility: Investigational Site Number 840225
state: Virginia
city: Richmond
country: United States
facility: Investigational Site Number 840022
state: Virginia
city: Richmond
country: United States
facility: Investigational Site Number 840078
state: Virginia
city: Richmond
country: United States
facility: Investigational Site Number 840110
state: Virginia
city: Roanoke
country: United States
facility: Investigational Site Number 840149
state: Virginia
city: Winchester
country: United States
facility: Investigational Site Number 840223
state: Virginia
city: Bellevue
country: United States
facility: Investigational Site Number 840025
state: Washington
city: Everett
country: United States
facility: Investigational Site Number 840321
state: Washington
city: Spokane
country: United States
facility: Investigational Site Number 840326
state: Washington
city: Tacoma
country: United States
facility: Investigational Site Number 840086
state: Washington
city: Walla Walla
country: United States
facility: Investigational Site Number 840295
state: Washington
city: Burlington
country: United States
facility: Investigational Site Number 840262
state: Wisconsin
city: Green Bay
country: United States
facility: Investigational Site Number 840298
state: Wisconsin
city: Green Bay
country: United States
facility: Investigational Site Number 840059
state: Wisconsin
city: La Crosse
country: United States
facility: Investigational Site Number 840177
state: Wisconsin
city: Manitowoc
country: United States
facility: Investigational Site Number 840300
state: Wisconsin
city: Adrogue
country: Argentina
facility: Investigational Site Number 032012
city: Bahia Blanca
country: Argentina
facility: Investigational Site Number 032018
city: Caba
country: Argentina
facility: Investigational Site Number 032050
city: Caba
country: Argentina
facility: Investigational Site Number 032048
city: Caba
country: Argentina
facility: Investigational Site Number 032023
city: Caba
country: Argentina
facility: Investigational Site Number 032020
city: Caba
country: Argentina
facility: Investigational Site Number 032041
city: Caba
country: Argentina
facility: Investigational Site Number 032011
city: Caba
country: Argentina
facility: Investigational Site Number 032045
city: Ciudad De Buenos Aires
country: Argentina
facility: Investigational Site Number 032010
city: Ciudadela
country: Argentina
facility: Investigational Site Number 032046
city: Cordoba
country: Argentina
facility: Investigational Site Number 032032
city: Cordoba
country: Argentina
facility: Investigational Site Number 032019
city: Cordoba
country: Argentina
facility: Investigational Site Number 032021
city: Cordoba
country: Argentina
facility: Investigational Site Number 032008
city: Cordoba
country: Argentina
facility: Investigational Site Number 032042
city: Cordoba
country: Argentina
facility: Investigational Site Number 032038
city: Cordoba
country: Argentina
facility: Investigational Site Number 032031
city: Coronel Suarez
country: Argentina
facility: Investigational Site Number 032017
city: Corrientes
country: Argentina
facility: Investigational Site Number 032009
city: Córdoba
country: Argentina
facility: Investigational Site Number 032026
city: Córdoba
country: Argentina
facility: Investigational Site Number 032049
city: Junin
country: Argentina
facility: Investigational Site Number 032005
city: La Plata
country: Argentina
facility: Investigational Site Number 032001
city: La Plata
country: Argentina
facility: Investigational Site Number 032040
city: Mar Del Plata
country: Argentina
facility: Investigational Site Number 032033
city: Mar Del Plata
country: Argentina
facility: Investigational Site Number 032014
city: Mendoza
country: Argentina
facility: Investigational Site Number 032016
city: Merlo
country: Argentina
facility: Investigational Site Number 032030
city: Moron
country: Argentina
facility: Investigational Site Number 032036
city: Olivos
country: Argentina
facility: Investigational Site Number 032007
city: Olivos
country: Argentina
facility: Investigational Site Number 032044
city: Quilmes
country: Argentina
facility: Investigational Site Number 032004
city: Rafaela
country: Argentina
facility: Investigational Site Number 032025
city: Ramos Mejia
country: Argentina
facility: Investigational Site Number 032035
city: Resistencia
country: Argentina
facility: Investigational Site Number 032039
city: Rosario
country: Argentina
facility: Investigational Site Number 032028
city: Rosario
country: Argentina
facility: Investigational Site Number 032024
city: Salta
country: Argentina
facility: Investigational Site Number 032053
city: San Isidro
country: Argentina
facility: Investigational Site Number 032037
city: San Martin
country: Argentina
facility: Investigational Site Number 032052
city: San Martin
country: Argentina
facility: Investigational Site Number 032013
city: San Miguel De Tucuman
country: Argentina
facility: Investigational Site Number 032002
city: San Miguel De Tucuman
country: Argentina
facility: Investigational Site Number 032034
city: San Nicolas
country: Argentina
facility: Investigational Site Number 032006
city: Santa Fe
country: Argentina
facility: Investigational Site Number 032043
city: Santa Fe
country: Argentina
facility: Investigational Site Number 032003
city: Santa Rosa
country: Argentina
facility: Investigational Site Number 032051
city: Santiago Del Estero
country: Argentina
facility: Investigational Site Number 032047
city: Venado Tuerto
country: Argentina
facility: Investigational Site Number 032029
city: Villa Maria
country: Argentina
facility: Investigational Site Number 032022
city: Zarate
country: Argentina
facility: Investigational Site Number 032015
city: Ashford
country: Australia
facility: Investigational Site Number 036002
city: Auchenflower
country: Australia
facility: Investigational Site Number 036023
city: Ballarat
country: Australia
facility: Investigational Site Number 036024
city: Bedford Park
country: Australia
facility: Investigational Site Number 036020
city: Bruce
country: Australia
facility: Investigational Site Number 036015
city: Cairns
country: Australia
facility: Investigational Site Number 036026
city: Chermside
country: Australia
facility: Investigational Site Number 036005
city: Chermside
country: Australia
facility: Investigational Site Number 036008
city: Coffs Harbour
country: Australia
facility: Investigational Site Number 036011
city: Concord
country: Australia
facility: Investigational Site Number 036003
city: Elizabeth Vale
country: Australia
facility: Investigational Site Number 036017
city: Fullarton
country: Australia
facility: Investigational Site Number 036006
city: Gosford
country: Australia
facility: Investigational Site Number 036004
city: Heidelberg West
country: Australia
facility: Investigational Site Number 036019
city: Hobart
country: Australia
facility: Investigational Site Number 036027
city: Kogarah
country: Australia
facility: Investigational Site Number 036009
city: Mildura
country: Australia
facility: Investigational Site Number 036012
city: Nambour
country: Australia
facility: Investigational Site Number 036028
city: New Lambton
country: Australia
facility: Investigational Site Number 036013
city: Perth
country: Australia
facility: Investigational Site Number 036010
city: Prahran
country: Australia
facility: Investigational Site Number 036014
city: Redcliffe
country: Australia
facility: Investigational Site Number 036018
city: Richmond
country: Australia
facility: Investigational Site Number 036022
city: Woodville South
country: Australia
facility: Investigational Site Number 036025
city: Woolloongabba
country: Australia
facility: Investigational Site Number 036021
city: Feldkirch
country: Austria
facility: Investigational Site Number 040004
city: Graz
country: Austria
facility: Investigational Site Number 040007
city: Salzburg
country: Austria
facility: Investigational Site Number 040001
city: Wien
country: Austria
facility: Investigational Site Number 040006
city: Wien
country: Austria
facility: Investigational Site Number 040003
city: Wien
country: Austria
facility: Investigational Site Number 040002
city: Aalst
country: Belgium
facility: Investigational Site Number 056016
city: Antwerpen
country: Belgium
facility: Investigational Site Number 056003
city: Antwerpen
country: Belgium
facility: Investigational Site Number 056002
city: Bonheiden
country: Belgium
facility: Investigational Site Number 056008
city: Brasschaat
country: Belgium
facility: Investigational Site Number 056014
city: Brussels
country: Belgium
facility: Investigational Site Number 056021
city: Bruxelles
country: Belgium
facility: Investigational Site Number 056005
city: Bruxelles
country: Belgium
facility: Investigational Site Number 056004
city: Edegem
country: Belgium
facility: Investigational Site Number 056017
city: Genk
country: Belgium
facility: Investigational Site Number 056024
city: Gent
country: Belgium
facility: Investigational Site Number 056007
city: Gent
country: Belgium
facility: Investigational Site Number 056018
city: La Louviere
country: Belgium
facility: Investigational Site Number 056020
city: Leuven
country: Belgium
facility: Investigational Site Number 056009
city: Liège
country: Belgium
facility: Investigational Site Number 056015
city: Mechelen
country: Belgium
facility: Investigational Site Number 056010
city: Mol
country: Belgium
facility: Investigational Site Number 056013
city: Ottignies
country: Belgium
facility: Investigational Site Number 056001
city: Overpelt
country: Belgium
facility: Investigational Site Number 056012
city: Roeselare
country: Belgium
facility: Investigational Site Number 056006
city: Tienen
country: Belgium
facility: Investigational Site Number 056019
city: Banja Luka
country: Bosnia and Herzegovina
facility: Investigational Site Number 070001
city: Banja Luka
country: Bosnia and Herzegovina
facility: Investigational Site Number 070002
city: Bihac
country: Bosnia and Herzegovina
facility: Investigational Site Number 070011
city: Mostar
country: Bosnia and Herzegovina
facility: Investigational Site Number 070003
city: Mostar
country: Bosnia and Herzegovina
facility: Investigational Site Number 070004
city: Sarajevo
country: Bosnia and Herzegovina
facility: Investigational Site Number 070005
city: Sarajevo
country: Bosnia and Herzegovina
facility: Investigational Site Number 070007
city: Sarajevo
country: Bosnia and Herzegovina
facility: Investigational Site Number 070010
city: Tuzla
country: Bosnia and Herzegovina
facility: Investigational Site Number 070008
city: Tuzla
country: Bosnia and Herzegovina
facility: Investigational Site Number 070009
city: Zenica
country: Bosnia and Herzegovina
facility: Investigational Site Number 070006
city: Aparecida De Goiania
country: Brazil
facility: Investigational Site Number 076029
city: Belem
country: Brazil
facility: Investigational Site Number 076032
city: Belo Horizonte
country: Brazil
facility: Investigational Site Number 076017
city: Belo Horizonte
country: Brazil
facility: Investigational Site Number 076004
city: Belo Horizonte
country: Brazil
facility: Investigational Site Number 076022
city: Belo Horizonte
country: Brazil
facility: Investigational Site Number 076038
city: Blumenau
country: Brazil
facility: Investigational Site Number 076002
city: Brasilia
country: Brazil
facility: Investigational Site Number 076011
city: Brasilia
country: Brazil
facility: Investigational Site Number 076007
city: Campina Grande Do Sul
country: Brazil
facility: Investigational Site Number 076003
city: Campinas
country: Brazil
facility: Investigational Site Number 076006
city: Canoas
country: Brazil
facility: Investigational Site Number 076040
city: Curitiba
country: Brazil
facility: Investigational Site Number 076033
city: Curitiba
country: Brazil
facility: Investigational Site Number 076005
city: Fortaleza
country: Brazil
facility: Investigational Site Number 076009
city: Fortaleza
country: Brazil
facility: Investigational Site Number 076008
city: Goiania
country: Brazil
facility: Investigational Site Number 076012
city: Goiania
country: Brazil
facility: Investigational Site Number 076021
city: Passo Fundo
country: Brazil
facility: Investigational Site Number 076019
city: Pelotas
country: Brazil
facility: Investigational Site Number 076018
city: Porto Alegre
country: Brazil
facility: Investigational Site Number 076024
city: Porto Alegre
country: Brazil
facility: Investigational Site Number 076026
city: Porto Alegre
country: Brazil
facility: Investigational Site Number 076014
city: Porto Alegre
country: Brazil
facility: Investigational Site Number 076001
city: Porto Alegre
country: Brazil
facility: Investigational Site Number 076027
city: Riberao Preto
country: Brazil
facility: Investigational Site Number 076035
city: Rio De Janeiro
country: Brazil
facility: Investigational Site Number 076010
city: Salvador
country: Brazil
facility: Investigational Site Number 076015
city: Salvador
country: Brazil
facility: Investigational Site Number 076041
city: Santo Andre
country: Brazil
facility: Investigational Site Number 076036
city: Sao Bernardo Do Campo
country: Brazil
facility: Investigational Site Number 076031
city: Sao Jose Do Rio Preto
country: Brazil
facility: Investigational Site Number 076030
city: Sao Jose Do Rio Preto
country: Brazil
facility: Investigational Site Number 076020
city: Sao Paulo
country: Brazil
facility: Investigational Site Number 076025
city: Sao Paulo
country: Brazil
facility: Investigational Site Number 076042
city: Sao Paulo
country: Brazil
facility: Investigational Site Number 076039
city: Sao Paulo
country: Brazil
facility: Investigational Site Number 076013
city: Sao Paulo
country: Brazil
facility: Investigational Site Number 076023
city: Sao Paulo
country: Brazil
facility: Investigational Site Number 076028
city: Tatuí
country: Brazil
facility: Investigational Site Number 076016
city: Uberlandia
country: Brazil
facility: Investigational Site Number 076034
city: Blagoevgrad
country: Bulgaria
facility: Investigational Site Number 100020
city: Burgas
country: Bulgaria
facility: Investigational Site Number 100012
city: Pazardzhik
country: Bulgaria
facility: Investigational Site Number 100011
city: Pleven
country: Bulgaria
facility: Investigational Site Number 100013
city: Pleven
country: Bulgaria
facility: Investigational Site Number 100018
city: Plovdiv
country: Bulgaria
facility: Investigational Site Number 100005
city: Sandanski
country: Bulgaria
facility: Investigational Site Number 100015
city: Smoljan
country: Bulgaria
facility: Investigational Site Number 100023
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100017
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100007
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100001
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100004
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100010
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100019
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100016
city: Sofia
country: Bulgaria
facility: Investigational Site Number 100003
city: Varna
country: Bulgaria
facility: Investigational Site Number 100022
city: Veliko Tarnovo
country: Bulgaria
facility: Investigational Site Number 100014
city: Calgary
country: Canada
facility: Investigational Site Number 124033
city: Cambridge
country: Canada
facility: Investigational Site Number 124017
city: Cambridge
country: Canada
facility: Investigational Site Number 124013
city: Edmonton
country: Canada
facility: Investigational Site Number 124026
city: Edmonton
country: Canada
facility: Investigational Site Number 124019
city: Edmonton
country: Canada
facility: Investigational Site Number 124016
city: Granby
country: Canada
facility: Investigational Site Number 124027
city: Halifax
country: Canada
facility: Investigational Site Number 124002
city: Hamilton
country: Canada
facility: Investigational Site Number 124051
city: Joliette
country: Canada
facility: Investigational Site Number 124043
city: Kitchener
country: Canada
facility: Investigational Site Number 124045
city: Levis
country: Canada
facility: Investigational Site Number 124053
city: Longueuil
country: Canada
facility: Investigational Site Number 124015
city: Moncton
country: Canada
facility: Investigational Site Number 124004
city: Montreal
country: Canada
facility: Investigational Site Number 124040
city: Montreal
country: Canada
facility: Investigational Site Number 124032
city: Montreal
country: Canada
facility: Investigational Site Number 124036
city: Montreal
country: Canada
facility: Investigational Site Number 124042
city: New Westminster
country: Canada
facility: Investigational Site Number 124028
city: Newmarket
country: Canada
facility: Investigational Site Number 124008
city: Oshawa
country: Canada
facility: Investigational Site Number 124005
city: Ottawa
country: Canada
facility: Investigational Site Number 124007
city: Penticton
country: Canada
facility: Investigational Site Number 124006
city: Red Deer
country: Canada
facility: Investigational Site Number 124012
city: Saint-Jerome
country: Canada
facility: Investigational Site Number 124054
city: Sainte-Foy
country: Canada
facility: Investigational Site Number 124024
city: Scarborough
country: Canada
facility: Investigational Site Number 124035
city: Sherbrooke
country: Canada
facility: Investigational Site Number 124047
city: St-Georges
country: Canada
facility: Investigational Site Number 124025
city: St. Catherines
country: Canada
facility: Investigational Site Number 124044
city: St. John'S
country: Canada
facility: Investigational Site Number 124034
city: St. John
country: Canada
facility: Investigational Site Number 124021
city: Surrey
country: Canada
facility: Investigational Site Number 124009
city: Sydney
country: Canada
facility: Investigational Site Number 124022
city: Thetford Mines
country: Canada
facility: Investigational Site Number 124048
city: Thunder Bay
country: Canada
facility: Investigational Site Number 124037
city: Toronto
country: Canada
facility: Investigational Site Number 124001
city: Trois-Rivieres
country: Canada
facility: Investigational Site Number 124049
city: Vancouver
country: Canada
facility: Investigational Site Number 124039
city: Victoria
country: Canada
facility: Investigational Site Number 124023
city: Victoria
country: Canada
facility: Investigational Site Number 124041
city: Winnipeg
country: Canada
facility: Investigational Site Number 124038
city: Concepcion
country: Chile
facility: Investigational Site Number 152013
city: Osorno
country: Chile
facility: Investigational Site Number 152003
city: Punta Arenas
country: Chile
facility: Investigational Site Number 152017
city: Santiago
country: Chile
facility: Investigational Site Number 152004
city: Santiago
country: Chile
facility: Investigational Site Number 152014
city: Santiago
country: Chile
facility: Investigational Site Number 152001
city: Santiago
country: Chile
facility: Investigational Site Number 152019
city: Santiago
country: Chile
facility: Investigational Site Number 152007
city: Santiago
country: Chile
facility: Investigational Site Number 152012
city: Santiago
country: Chile
facility: Investigational Site Number 152011
city: Santiago
country: Chile
facility: Investigational Site Number 152006
city: Santiago
country: Chile
facility: Investigational Site Number 152016
city: Santiago
country: Chile
facility: Investigational Site Number 152015
city: Talca
country: Chile
facility: Investigational Site Number 152009
city: Temuco
country: Chile
facility: Investigational Site Number 152002
city: Valdivia
country: Chile
facility: Investigational Site Number 152008
city: Viña Del Mar
country: Chile
facility: Investigational Site Number 152010
city: Viña Del Mar
country: Chile
facility: Investigational Site Number 152018
city: Baotou
country: China
facility: Investigational Site Number 156022
city: Beijing
country: China
facility: Investigational Site Number 156004
city: Beijing
country: China
facility: Investigational Site Number 156005
city: Beijing
country: China
facility: Investigational Site Number 156006
city: Beijing
country: China
facility: Investigational Site Number 156001
city: Beijing
country: China
facility: Investigational Site Number 156082
city: Beijing
country: China
facility: Investigational Site Number 156009
city: Beijing
country: China
facility: Investigational Site Number 156003
city: Beijing
country: China
facility: Investigational Site Number 156002
city: Changchun
country: China
facility: Investigational Site Number 156013
city: Changchun
country: China
facility: Investigational Site Number 156064
city: Changsha
country: China
facility: Investigational Site Number 156052
city: Changsha
country: China
facility: Investigational Site Number 156053
city: Changsha
country: China
facility: Investigational Site Number 156088
city: Chongqing
country: China
facility: Investigational Site Number 156057
city: Fuzhou
country: China
facility: Investigational Site Number 156070
city: Fuzhou
country: China
facility: Investigational Site Number 156079
city: Guangzhou
country: China
facility: Investigational Site Number 156059
city: Guangzhou
country: China
facility: Investigational Site Number 156060
city: Guangzhou
country: China
facility: Investigational Site Number 156071
city: Guangzhou
country: China
facility: Investigational Site Number 156061
city: Guiyang
country: China
facility: Investigational Site Number 156072
city: Hangzhou
country: China
facility: Investigational Site Number 156047
city: Hangzhou
country: China
facility: Investigational Site Number 156077
city: Hangzhou
country: China
facility: Investigational Site Number 156048
city: Hangzhou
country: China
facility: Investigational Site Number 156068
city: Hangzhou
country: China
facility: Investigational Site Number 156078
city: Hangzhou
country: China
facility: Investigational Site Number 156046
city: Hohhot
country: China
facility: Investigational Site Number 156020
city: Jinan
country: China
facility: Investigational Site Number 156032
city: Jinan
country: China
facility: Investigational Site Number 156031
city: Lanzhou
country: China
facility: Investigational Site Number 156027
city: Lanzhou
country: China
facility: Investigational Site Number 156074
city: Luzhou
country: China
facility: Investigational Site Number 156081
city: Nanchang
country: China
facility: Investigational Site Number 156054
city: Nanchang
country: China
facility: Investigational Site Number 156055
city: Nanjing
country: China
facility: Investigational Site Number 156034
city: Nanjing
country: China
facility: Investigational Site Number 156035
city: Shanghai
country: China
facility: Investigational Site Number 156039
city: Shanghai
country: China
facility: Investigational Site Number 156076
city: Shanghai
country: China
facility: Investigational Site Number 156044
city: Shanghai
country: China
facility: Investigational Site Number 156043
city: Shanghai
country: China
facility: Investigational Site Number 156038
city: Shanghai
country: China
facility: Investigational Site Number 156040
city: Shenyang
country: China
facility: Investigational Site Number 156016
city: Shenyang
country: China
facility: Investigational Site Number 156017
city: Shenzhen
country: China
facility: Investigational Site Number 156073
city: Shenzhen
country: China
facility: Investigational Site Number 156084
city: Siping
country: China
facility: Investigational Site Number 156063
city: Suzhou
country: China
facility: Investigational Site Number 156037
city: Tianjin
country: China
facility: Investigational Site Number 156066
city: Tianjin
country: China
facility: Investigational Site Number 156067
city: Tianjin
country: China
facility: Investigational Site Number 156083
city: Tianjin
country: China
facility: Investigational Site Number 156025
city: Wenzhou
country: China
facility: Investigational Site Number 156065
city: Wuhan
country: China
facility: Investigational Site Number 156051
city: Wuhan
country: China
facility: Investigational Site Number 156087
city: Xi'An
country: China
facility: Investigational Site Number 156029
city: Xi'An
country: China
facility: Investigational Site Number 156086
city: Xuzhou
country: China
facility: Investigational Site Number 156062
city: Yanji
country: China
facility: Investigational Site Number 156014
city: Yueyang
country: China
facility: Investigational Site Number 156075
city: Zhanjiang
country: China
facility: Investigational Site Number 156080
city: Armenia
country: Colombia
facility: Investigational Site Number 170006
city: Barranquilla
country: Colombia
facility: Investigational Site Number 170003
city: Barranquilla
country: Colombia
facility: Investigational Site Number 170011
city: Barranquilla
country: Colombia
facility: Investigational Site Number 170013
city: Bogota D.C.
country: Colombia
facility: Investigational Site Number 170022
city: Bogota
country: Colombia
facility: Investigational Site Number 170018
city: Bogota
country: Colombia
facility: Investigational Site Number 170016
city: Cali
country: Colombia
facility: Investigational Site Number 170010
city: Cali
country: Colombia
facility: Investigational Site Number 170001
city: Cartagena
country: Colombia
facility: Investigational Site Number 170017
city: Cartagena
country: Colombia
facility: Investigational Site Number 170004
city: Espinal - Tolima
country: Colombia
facility: Investigational Site Number 170008
city: Floridablanca
country: Colombia
facility: Investigational Site Number 170005
city: Manizales
country: Colombia
facility: Investigational Site Number 170002
city: Medellin
country: Colombia
facility: Investigational Site Number 170007
city: Medellin
country: Colombia
facility: Investigational Site Number 170009
city: Medellin
country: Colombia
facility: Investigational Site Number 170021
city: Dubrovnik
country: Croatia
facility: Investigational Site Number 191013
city: Krapinske Toplice
country: Croatia
facility: Investigational Site Number 191017
city: Opatija
country: Croatia
facility: Investigational Site Number 191009
city: Rijeka
country: Croatia
facility: Investigational Site Number 191006
city: Slavonski Brod
country: Croatia
facility: Investigational Site Number 191012
city: Varazdin
country: Croatia
facility: Investigational Site Number 191003
city: Zagreb
country: Croatia
facility: Investigational Site Number 191001
city: Zagreb
country: Croatia
facility: Investigational Site Number 191002
city: Zagreb
country: Croatia
facility: Investigational Site Number 191005
city: Zagreb
country: Croatia
facility: Investigational Site Number 191007
city: Zagreb
country: Croatia
facility: Investigational Site Number 191008
city: Zagreb
country: Croatia
facility: Investigational Site Number 191010
city: Zagreb
country: Croatia
facility: Investigational Site Number 191011
city: Zagreb
country: Croatia
facility: Investigational Site Number 191015
city: Zagreb
country: Croatia
facility: Investigational Site Number 191016
city: Zagreb
country: Croatia
facility: Investigational Site Number 191018
city: Brno
country: Czechia
facility: Investigational Site Number 203003
city: Ceska Lipa
country: Czechia
facility: Investigational Site Number 203020
city: Cesky Krumlov
country: Czechia
facility: Investigational Site Number 203025
city: Hodonin
country: Czechia
facility: Investigational Site Number 203023
city: Hradec Kralove
country: Czechia
facility: Investigational Site Number 203006
city: Kladno
country: Czechia
facility: Investigational Site Number 203019
city: Kladno
country: Czechia
facility: Investigational Site Number 203005
city: Kromeriz
country: Czechia
facility: Investigational Site Number 203008
city: Liberec
country: Czechia
facility: Investigational Site Number 203015
city: Marianske Lazne
country: Czechia
facility: Investigational Site Number 203024
city: Olomouc
country: Czechia
facility: Investigational Site Number 203013
city: Ostrava
country: Czechia
facility: Investigational Site Number 203016
city: Pardubice
country: Czechia
facility: Investigational Site Number 203014
city: Plzen
country: Czechia
facility: Investigational Site Number 203018
city: Praha 10
country: Czechia
facility: Investigational Site Number 203011
city: Praha 2
country: Czechia
facility: Investigational Site Number 203017
city: Praha 4
country: Czechia
facility: Investigational Site Number 203004
city: Praha 4
country: Czechia
facility: Investigational Site Number 203021
city: Praha 5 - Motol
country: Czechia
facility: Investigational Site Number 203007
city: Praha 5
country: Czechia
facility: Investigational Site Number 203012
city: Rakovnik
country: Czechia
facility: Investigational Site Number 203009
city: Zlin
country: Czechia
facility: Investigational Site Number 203010
city: Aabenraa
country: Denmark
facility: Investigational Site Number 208016
city: Aalborg
country: Denmark
facility: Investigational Site Number 208012
city: Aarhus N
country: Denmark
facility: Investigational Site Number 208011
city: Copenhagen
country: Denmark
facility: Investigational Site Number 208002
city: Glostrup
country: Denmark
facility: Investigational Site Number 208003
city: Hellerup
country: Denmark
facility: Investigational Site Number 208007
city: Herning
country: Denmark
facility: Investigational Site Number 208006
city: Hillerød
country: Denmark
facility: Investigational Site Number 208018
city: Holbaek
country: Denmark
facility: Investigational Site Number 208014
city: Hvidovre
country: Denmark
facility: Investigational Site Number 208013
city: Køge
country: Denmark
facility: Investigational Site Number 208004
city: Næstved
country: Denmark
facility: Investigational Site Number 208017
city: Odense C
country: Denmark
facility: Investigational Site Number 208009
city: Silkeborg
country: Denmark
facility: Investigational Site Number 208015
city: Slagelse
country: Denmark
facility: Investigational Site Number 208008
city: Vejle
country: Denmark
facility: Investigational Site Number 208001
city: Viborg
country: Denmark
facility: Investigational Site Number 208010
city: Pärnu
country: Estonia
facility: Investigational Site Number 233007
city: Tallinn
country: Estonia
facility: Investigational Site Number 233004
city: Tallinn
country: Estonia
facility: Investigational Site Number 233002
city: Tallinn
country: Estonia
facility: Investigational Site Number 233001
city: Tallinn
country: Estonia
facility: Investigational Site Number 233005
city: Tartu
country: Estonia
facility: Investigational Site Number 233003
city: Viljandimaa
country: Estonia
facility: Investigational Site Number 233006
city: Helsinki
country: Finland
facility: Investigational Site Number 246004
city: Oulu
country: Finland
facility: Investigational Site Number 246001
city: Tampere
country: Finland
facility: Investigational Site Number 246003
city: Turku
country: Finland
facility: Investigational Site Number 246002
city: Besancon
country: France
facility: Investigational Site Number 250003
city: Brest Cedex
country: France
facility: Investigational Site Number 250007
city: Cambrai Cedex
country: France
facility: Investigational Site Number 250010
city: Clermont-Ferrand Cedex 1
country: France
facility: Investigational Site Number 250018
city: Compiegne
country: France
facility: Investigational Site Number 250021
city: Dijon
country: France
facility: Investigational Site Number 250002
city: Grenoble
country: France
facility: Investigational Site Number 250001
city: Limoges Cedex 1
country: France
facility: Investigational Site Number 250009
city: Marseille
country: France
facility: Investigational Site Number 250019
city: Massy
country: France
facility: Investigational Site Number 250008
city: Montfermeil
country: France
facility: Investigational Site Number 250005
city: Montpellier Cedex 5
country: France
facility: Investigational Site Number 250023
city: Nantes
country: France
facility: Investigational Site Number 250025
city: Nice Cedex 01
country: France
facility: Investigational Site Number 250017
city: Paris Cedex 12
country: France
facility: Investigational Site Number 250015
city: Paris
country: France
facility: Investigational Site Number 250020
city: Paris
country: France
facility: Investigational Site Number 250012
city: Paris
country: France
facility: Investigational Site Number 250004
city: Pau
country: France
facility: Investigational Site Number 250011
city: Pessac
country: France
facility: Investigational Site Number 250016
city: Rouen
country: France
facility: Investigational Site Number 250026
city: Strasbourg Cedex
country: France
facility: Investigational Site Number 250022
city: Batumi
country: Georgia
facility: Investigational Site Number 268004
city: Kutaisi
country: Georgia
facility: Investigational Site Number 268001
city: Tbilisi
country: Georgia
facility: Investigational Site Number 268005
city: Tbilisi
country: Georgia
facility: Investigational Site Number 268002
city: Tbilisi
country: Georgia
facility: Investigational Site Number 268003
city: Tbilisi
country: Georgia
facility: Investigational Site Number 268008
city: Tbilisi
country: Georgia
facility: Investigational Site Number 268009
city: Aachen
country: Germany
facility: Investigational Site Number 276013
city: Bad Krozingen
country: Germany
facility: Investigational Site Number 276019
city: Berlin
country: Germany
facility: Investigational Site Number 276008
city: Berlin
country: Germany
facility: Investigational Site Number 276040
city: Berlin
country: Germany
facility: Investigational Site Number 276051
city: Berlin
country: Germany
facility: Investigational Site Number 276039
city: Berlin
country: Germany
facility: Investigational Site Number 276025
city: Bernau
country: Germany
facility: Investigational Site Number 276054
city: Bielefeld
country: Germany
facility: Investigational Site Number 276037
city: Bonn
country: Germany
facility: Investigational Site Number 276016
city: Bonn
country: Germany
facility: Investigational Site Number 276009
city: Dortmund
country: Germany
facility: Investigational Site Number 276001
city: Dortmund
country: Germany
facility: Investigational Site Number 276006
city: Dortmund
country: Germany
facility: Investigational Site Number 276031
city: Dresden
country: Germany
facility: Investigational Site Number 276050
city: Eschweiler
country: Germany
facility: Investigational Site Number 276024
city: Essen
country: Germany
facility: Investigational Site Number 276028
city: Frankfurt Am Main
country: Germany
facility: Investigational Site Number 276036
city: Freiburg
country: Germany
facility: Investigational Site Number 276012
city: Halle/Saale
country: Germany
facility: Investigational Site Number 276030
city: Hamburg
country: Germany
facility: Investigational Site Number 276032
city: Hamburg
country: Germany
facility: Investigational Site Number 276017
city: Hamburg
country: Germany
facility: Investigational Site Number 276027
city: Hamm
country: Germany
facility: Investigational Site Number 276029
city: Haßloch
country: Germany
facility: Investigational Site Number 276052
city: Heidelberg
country: Germany
facility: Investigational Site Number 276014
city: Homburg/Saar
country: Germany
facility: Investigational Site Number 276023
city: Kassel
country: Germany
facility: Investigational Site Number 276035
city: Leipzig
country: Germany
facility: Investigational Site Number 276046
city: Limburg
country: Germany
facility: Investigational Site Number 276020
city: Lippstadt
country: Germany
facility: Investigational Site Number 276026
city: Lübeck
country: Germany
facility: Investigational Site Number 276044
city: Magdeburg
country: Germany
facility: Investigational Site Number 276021
city: Mainz
country: Germany
facility: Investigational Site Number 276015
city: Marburg
country: Germany
facility: Investigational Site Number 276010
city: Münster
country: Germany
facility: Investigational Site Number 276018
city: Nürnberg
country: Germany
facility: Investigational Site Number 276042
city: Peine
country: Germany
facility: Investigational Site Number 276048
city: Rotenburg An Der Fulda
country: Germany
facility: Investigational Site Number 276053
city: Rüdersdorf Bei Berlin
country: Germany
facility: Investigational Site Number 276045
city: Stuttgart
country: Germany
facility: Investigational Site Number 276002
city: Warendorf
country: Germany
facility: Investigational Site Number 276033
city: Athens
country: Greece
facility: Investigational Site Number 300001
city: Athens
country: Greece
facility: Investigational Site Number 300002
city: Athens
country: Greece
facility: Investigational Site Number 300007
city: Chios
country: Greece
facility: Investigational Site Number 300008
city: Haidari
country: Greece
facility: Investigational Site Number 300013
city: Heraklion
country: Greece
facility: Investigational Site Number 300010
city: Ioannina
country: Greece
facility: Investigational Site Number 300005
city: Marousi
country: Greece
facility: Investigational Site Number 300003
city: N. Ionia
country: Greece
facility: Investigational Site Number 300006
city: Patra
country: Greece
facility: Investigational Site Number 300004
city: Thessaloniki
country: Greece
facility: Investigational Site Number 300011
city: Thessaloniki
country: Greece
facility: Investigational Site Number 300009
city: Guatemala
country: Guatemala
facility: Investigational Site Number 320003
city: Guatemala
country: Guatemala
facility: Investigational Site Number 320001
city: Guatemala
country: Guatemala
facility: Investigational Site Number 320002
city: Guatemala
country: Guatemala
facility: Investigational Site Number 320004
city: Hong Kong
country: Hong Kong
facility: Investigational Site Number 344003
city: Shatin, Nt
country: Hong Kong
facility: Investigational Site Number 344001
city: Balatonfüred
country: Hungary
facility: Investigational Site Number 348013
city: Budapest
country: Hungary
facility: Investigational Site Number 348002
city: Budapest
country: Hungary
facility: Investigational Site Number 348012
city: Budapest
country: Hungary
facility: Investigational Site Number 348005
city: Budapest
country: Hungary
facility: Investigational Site Number 348006
city: Debrecen
country: Hungary
facility: Investigational Site Number 348008
city: Eger
country: Hungary
facility: Investigational Site Number 348004
city: Gyula
country: Hungary
facility: Investigational Site Number 348003
city: Pécs
country: Hungary
facility: Investigational Site Number 348010
city: Szeged
country: Hungary
facility: Investigational Site Number 348009
city: Szekesfehervar
country: Hungary
facility: Investigational Site Number 348007
city: Szombathely
country: Hungary
facility: Investigational Site Number 348011
city: Zalaegerszeg
country: Hungary
facility: Investigational Site Number 348001
city: Ahmedabad
country: India
facility: Investigational Site Number 356060
city: Aurangabad
country: India
facility: Investigational Site Number 356056
city: Bangalore
country: India
facility: Investigational Site Number 356025
city: Bangalore
country: India
facility: Investigational Site Number 356028
city: Bangalore
country: India
facility: Investigational Site Number 356083
city: Bangalore
country: India
facility: Investigational Site Number 356018
city: Bangalore
country: India
facility: Investigational Site Number 356026
city: Bangalore
country: India
facility: Investigational Site Number 356084
city: Belgaum
country: India
facility: Investigational Site Number 356103
city: Bikaner
country: India
facility: Investigational Site Number 356019
city: Chennai
country: India
facility: Investigational Site Number 356013
city: Chennai
country: India
facility: Investigational Site Number 356012
city: Chennai
country: India
facility: Investigational Site Number 356081
city: Delhi
country: India
facility: Investigational Site Number 356093
city: Delhi
country: India
facility: Investigational Site Number 356038
city: Gurgaon
country: India
facility: Investigational Site Number 356101
city: Gurgaon
country: India
facility: Investigational Site Number 356100
city: Hyderabad
country: India
facility: Investigational Site Number 356035
city: Hyderabad
country: India
facility: Investigational Site Number 356082
city: Jaipur
country: India
facility: Investigational Site Number 356015
city: Karad
country: India
facility: Investigational Site Number 356053
city: Karamsad
country: India
facility: Investigational Site Number 356102
city: Kochi
country: India
facility: Investigational Site Number 356022
city: Kolhapur
country: India
facility: Investigational Site Number 356106
city: Kolkata
country: India
facility: Investigational Site Number 356067
city: Kolkata
country: India
facility: Investigational Site Number 356079
city: Kolkata
country: India
facility: Investigational Site Number 356069
city: Ludhiana
country: India
facility: Investigational Site Number 356089
city: Mangalore
country: India
facility: Investigational Site Number 356095
city: Mumbai
country: India
facility: Investigational Site Number 356071
city: Mumbai
country: India
facility: Investigational Site Number 356057
city: Mysore
country: India
facility: Investigational Site Number 356007
city: Nagpur
country: India
facility: Investigational Site Number 356087
city: Nagpur
country: India
facility: Investigational Site Number 356098
city: Nagpur
country: India
facility: Investigational Site Number 356097
city: Nashik
country: India
facility: Investigational Site Number 356096
city: New Delhi
country: India
facility: Investigational Site Number 356055
city: New Delhi
country: India
facility: Investigational Site Number 356031
city: Panaji
country: India
facility: Investigational Site Number 356041
city: Pune
country: India
facility: Investigational Site Number 356077
city: Pune
country: India
facility: Investigational Site Number 356099
city: Pune
country: India
facility: Investigational Site Number 356048
city: Pune
country: India
facility: Investigational Site Number 356049
city: Pune
country: India
facility: Investigational Site Number 356050
city: Pune
country: India
facility: Investigational Site Number 356045
city: Pune
country: India
facility: Investigational Site Number 356046
city: Pune
country: India
facility: Investigational Site Number 356094
city: Secunderabad, Hyderabad
country: India
facility: Investigational Site Number 356042
city: Secunderabad
country: India
facility: Investigational Site Number 356009
city: Secunderabad
country: India
facility: Investigational Site Number 356032
city: Surat
country: India
facility: Investigational Site Number 356091
city: Vijayawada
country: India
facility: Investigational Site Number 356002
city: Vijaywada
country: India
facility: Investigational Site Number 356105
city: Visakhapatnam
country: India
facility: Investigational Site Number 356033
city: Vishkhapattanam
country: India
facility: Investigational Site Number 356039
city: Wardha
country: India
facility: Investigational Site Number 356104
city: Afula
country: Israel
facility: Investigational Site Number 376006
city: Afula
country: Israel
facility: Investigational Site Number 376024
city: Ashkelon
country: Israel
facility: Investigational Site Number 376009
city: Beer Sheva
country: Israel
facility: Investigational Site Number 376012
city: Haifa
country: Israel
facility: Investigational Site Number 376011
city: Haifa
country: Israel
facility: Investigational Site Number 376017
city: Haifa
country: Israel
facility: Investigational Site Number 376025
city: Haifa
country: Israel
facility: Investigational Site Number 376018
city: Holon
country: Israel
facility: Investigational Site Number 376007
city: Holon
country: Israel
facility: Investigational Site Number 376021
city: Jerusalem
country: Israel
facility: Investigational Site Number 376016
city: Jerusalem
country: Israel
facility: Investigational Site Number 376005
city: Jerusalem
country: Israel
facility: Investigational Site Number 376027
city: Kfar Saba
country: Israel
facility: Investigational Site Number 376002
city: Kfar Saba
country: Israel
facility: Investigational Site Number 376013
city: Nahariya
country: Israel
facility: Investigational Site Number 376004
city: Nazareth
country: Israel
facility: Investigational Site Number 376015
city: Petah-Tikva
country: Israel
facility: Investigational Site Number 376001
city: Petah-Tikva
country: Israel
facility: Investigational Site Number 376019
city: Rehovot
country: Israel
facility: Investigational Site Number 376020
city: Safed
country: Israel
facility: Investigational Site Number 376003
city: Safed
country: Israel
facility: Investigational Site Number 376008
city: Tel Aviv
country: Israel
facility: Investigational Site Number 376010
city: Tel Aviv
country: Israel
facility: Investigational Site Number 376014
city: Tel Hashomer
country: Israel
facility: Investigational Site Number 376022
city: Tiberias
country: Israel
facility: Investigational Site Number 376023
city: Tzrifin
country: Israel
facility: Investigational Site Number 376026
city: Augusta
country: Italy
facility: Investigational Site Number 380019
city: Bergamo
country: Italy
facility: Investigational Site Number 380017
city: Brescia
country: Italy
facility: Investigational Site Number 380026
city: Brescia
country: Italy
facility: Investigational Site Number 380008
city: Ferrara
country: Italy
facility: Investigational Site Number 380012
city: Forlì
country: Italy
facility: Investigational Site Number 380027
city: Livorno
country: Italy
facility: Investigational Site Number 380015
city: Massa
country: Italy
facility: Investigational Site Number 380033
city: Milano
country: Italy
facility: Investigational Site Number 380030
city: Milano
country: Italy
facility: Investigational Site Number 380005
city: Milano
country: Italy
facility: Investigational Site Number 380003
city: Monza
country: Italy
facility: Investigational Site Number 380025
city: Napoli
country: Italy
facility: Investigational Site Number 380001
city: Napoli
country: Italy
facility: Investigational Site Number 380002
city: Novara
country: Italy
facility: Investigational Site Number 380021
city: Osio Sotto
country: Italy
facility: Investigational Site Number 380009
city: Palermo
country: Italy
facility: Investigational Site Number 380007
city: Perugia
country: Italy
facility: Investigational Site Number 380013
city: Rho
country: Italy
facility: Investigational Site Number 380031
city: Rimini
country: Italy
facility: Investigational Site Number 380014
city: Roma
country: Italy
facility: Investigational Site Number 380024
city: Seriate
country: Italy
facility: Investigational Site Number 380028
city: Treviso
country: Italy
facility: Investigational Site Number 380032
city: Vittorio Veneto
country: Italy
facility: Investigational Site Number 380020
city: Amagasaki-Shi
country: Japan
facility: Investigational Site Number 392013
city: Amagasaki-Shi
country: Japan
facility: Investigational Site Number 392041
city: Fukuoka-Shi
country: Japan
facility: Investigational Site Number 392029
city: Hachioji-Shi
country: Japan
facility: Investigational Site Number 392019
city: Higashihiroshima-Shi
country: Japan
facility: Investigational Site Number 392026
city: Higashiibaraki-Gun
country: Japan
facility: Investigational Site Number 392024
city: Hiroshima-Shi
country: Japan
facility: Investigational Site Number 392003
city: Itabashi-Ku
country: Japan
facility: Investigational Site Number 392002
city: Itabashi-Ku
country: Japan
facility: Investigational Site Number 392014
city: Izumisano-Shi
country: Japan
facility: Investigational Site Number 392033
city: Kanazawa-Shi
country: Japan
facility: Investigational Site Number 392020
city: Kitakyushu-Shi
country: Japan
facility: Investigational Site Number 392015
city: Kobe-Shi
country: Japan
facility: Investigational Site Number 392017
city: Kobe-Shi
country: Japan
facility: Investigational Site Number 392028
city: Kobe-Shi
country: Japan
facility: Investigational Site Number 392037
city: Koga-Shi
country: Japan
facility: Investigational Site Number 392025
city: Komatsu-Shi
country: Japan
facility: Investigational Site Number 392010
city: Komatsushima-Shi
country: Japan
facility: Investigational Site Number 392035
city: Kumamoto-Shi
country: Japan
facility: Investigational Site Number 392023
city: Kumamoto-Shi
country: Japan
facility: Investigational Site Number 392031
city: Kure-Shi
country: Japan
facility: Investigational Site Number 392039
city: Kurume-Shi
country: Japan
facility: Investigational Site Number 392012
city: Kusatsu-Shi
country: Japan
facility: Investigational Site Number 392032
city: Kyoto City
country: Japan
facility: Investigational Site Number 392001
city: Minato-Ku
country: Japan
facility: Investigational Site Number 392027
city: Morioka-Shi
country: Japan
facility: Investigational Site Number 392016
city: Nagoya-Shi
country: Japan
facility: Investigational Site Number 392005
city: Nerima-Ku
country: Japan
facility: Investigational Site Number 392022
city: Osaka-Shi
country: Japan
facility: Investigational Site Number 392009
city: Osaka-Shi
country: Japan
facility: Investigational Site Number 392011
city: Osaka-Shi
country: Japan
facility: Investigational Site Number 392040
city: Sagamihara-Shi
country: Japan
facility: Investigational Site Number 392004
city: Sapporo-Shi
country: Japan
facility: Investigational Site Number 392036
city: Shinagawa-Ku
country: Japan
facility: Investigational Site Number 392034
city: Suita-Shi
country: Japan
facility: Investigational Site Number 392018
city: Tokushima-Shi
country: Japan
facility: Investigational Site Number 392030
city: Urasoe-Shi
country: Japan
facility: Investigational Site Number 392008
city: Yokohama-Shi
country: Japan
facility: Investigational Site Number 392006
city: Yokohama-Shi
country: Japan
facility: Investigational Site Number 392021
city: Busan
country: Korea, Republic of
facility: Investigational Site Number 410013
city: Busan
country: Korea, Republic of
facility: Investigational Site Number 410003
city: Daegu
country: Korea, Republic of
facility: Investigational Site Number 410002
city: Goyang-Si
country: Korea, Republic of
facility: Investigational Site Number 410012
city: Gwangju
country: Korea, Republic of
facility: Investigational Site Number 410001
city: Seongnam
country: Korea, Republic of
facility: Investigational Site Number 410008
city: Seoul
country: Korea, Republic of
facility: Investigational Site Number 410004
city: Seoul
country: Korea, Republic of
facility: Investigational Site Number 410007
city: Seoul
country: Korea, Republic of
facility: Investigational Site Number 410010
city: Seoul
country: Korea, Republic of
facility: Investigational Site Number 410011
city: Seoul
country: Korea, Republic of
facility: Investigational Site Number 410006
city: Suwon
country: Korea, Republic of
facility: Investigational Site Number 410009
city: Wonju
country: Korea, Republic of
facility: Investigational Site Number 410005
city: Daugavpils
country: Latvia
facility: Investigational Site Number 428004
city: Liepaja
country: Latvia
facility: Investigational Site Number 428002
city: Riga
country: Latvia
facility: Investigational Site Number 428006
city: Riga
country: Latvia
facility: Investigational Site Number 428001
city: Riga
country: Latvia
facility: Investigational Site Number 428005
city: Ventspils
country: Latvia
facility: Investigational Site Number 428003
city: Kaunas
country: Lithuania
facility: Investigational Site Number 440004
city: Kaunas
country: Lithuania
facility: Investigational Site Number 440005
city: Kaunas
country: Lithuania
facility: Investigational Site Number 440009
city: Kaunas
country: Lithuania
facility: Investigational Site Number 440008
city: Klaipeda
country: Lithuania
facility: Investigational Site Number 440001
city: Klaipeda
country: Lithuania
facility: Investigational Site Number 440006
city: Vilnius
country: Lithuania
facility: Investigational Site Number 440002
city: Vilnius
country: Lithuania
facility: Investigational Site Number 440007
city: Vilnius
country: Lithuania
facility: Investigational Site Number 440003
city: Bitola
country: Macedonia, The Former Yugoslav Republic of
facility: Investigational Site Number 807005
city: Shtip
country: Macedonia, The Former Yugoslav Republic of
facility: Investigational Site Number 807004
city: Skopje
country: Macedonia, The Former Yugoslav Republic of
facility: Investigational Site Number 807002
city: Skopje
country: Macedonia, The Former Yugoslav Republic of
facility: Investigational Site Number 807001
city: Tetovo
country: Macedonia, The Former Yugoslav Republic of
facility: Investigational Site Number 807003
city: Batu Caves
country: Malaysia
facility: Investigational Site Number 458004
city: Kota Bharu
country: Malaysia
facility: Investigational Site Number 458007
city: Kota Kinabalu
country: Malaysia
facility: Investigational Site Number 458006
city: Kuala Lumpur
country: Malaysia
facility: Investigational Site Number 458002
city: Kuala Lumpur
country: Malaysia
facility: Investigational Site Number 458005
city: Kuching
country: Malaysia
facility: Investigational Site Number 458003
city: Sungai Buloh
country: Malaysia
facility: Investigational Site Number 458001
city: Aguascalientes
country: Mexico
facility: Investigational Site Number 484005
city: Aguascalientes
country: Mexico
facility: Investigational Site Number 484015
city: Culiacan
country: Mexico
facility: Investigational Site Number 484004
city: Durango
country: Mexico
facility: Investigational Site Number 484003
city: Guadalajara
country: Mexico
facility: Investigational Site Number 484010
city: Guadalajara
country: Mexico
facility: Investigational Site Number 484006
city: Jalapa
country: Mexico
facility: Investigational Site Number 484008
city: Mexico D.F.
country: Mexico
facility: Investigational Site Number 484019
city: Mexico Df
country: Mexico
facility: Investigational Site Number 484023
city: Mexico
country: Mexico
facility: Investigational Site Number 484027
city: Monterrey
country: Mexico
facility: Investigational Site Number 484013
city: Monterrey
country: Mexico
facility: Investigational Site Number 484018
city: Monterrey
country: Mexico
facility: Investigational Site Number 484011
city: Monterrey
country: Mexico
facility: Investigational Site Number 484007
city: Morelia
country: Mexico
facility: Investigational Site Number 484017
city: Oaxaca
country: Mexico
facility: Investigational Site Number 484012
city: Querétaro
country: Mexico
facility: Investigational Site Number 484014
city: San Luis Potosi
country: Mexico
facility: Investigational Site Number 484009
city: Tijuana
country: Mexico
facility: Investigational Site Number 484002
city: Toluca
country: Mexico
facility: Investigational Site Number 484020
city: Alkmaar
country: Netherlands
facility: Investigational Site Number 528006
city: Amsterdam
country: Netherlands
facility: Investigational Site Number 528022
city: Amsterdam
country: Netherlands
facility: Investigational Site Number 528026
city: Apeldoorn
country: Netherlands
facility: Investigational Site Number 528021
city: Arnhem
country: Netherlands
facility: Investigational Site Number 528029
city: Breda
country: Netherlands
facility: Investigational Site Number 528004
city: Delft
country: Netherlands
facility: Investigational Site Number 528002
city: Eindhoven
country: Netherlands
facility: Investigational Site Number 528007
city: Goes
country: Netherlands
facility: Investigational Site Number 528032
city: Gouda
country: Netherlands
facility: Investigational Site Number 528012
city: Groningen
country: Netherlands
facility: Investigational Site Number 528001
city: Haarlem
country: Netherlands
facility: Investigational Site Number 528025
city: Hardenberg
country: Netherlands
facility: Investigational Site Number 528023
city: Heerenveen
country: Netherlands
facility: Investigational Site Number 528024
city: Hoorn
country: Netherlands
facility: Investigational Site Number 528016
city: Leeuwarden
country: Netherlands
facility: Investigational Site Number 528019
city: Leiden
country: Netherlands
facility: Investigational Site Number 528008
city: Meppel
country: Netherlands
facility: Investigational Site Number 528017
city: Nieuwegein
country: Netherlands
facility: Investigational Site Number 528030
city: Nijmegen
country: Netherlands
facility: Investigational Site Number 528011
city: Purmerend
country: Netherlands
facility: Investigational Site Number 528015
city: Roosendaal
country: Netherlands
facility: Investigational Site Number 528018
city: Rotterdam
country: Netherlands
facility: Investigational Site Number 528014
city: Rotterdam
country: Netherlands
facility: Investigational Site Number 528027
city: Sneek
country: Netherlands
facility: Investigational Site Number 528005
city: Tiel
country: Netherlands
facility: Investigational Site Number 528034
city: Tilburg
country: Netherlands
facility: Investigational Site Number 528013
city: Uden
country: Netherlands
facility: Investigational Site Number 528028
city: Venlo
country: Netherlands
facility: Investigational Site Number 528009
city: Zaandam
country: Netherlands
facility: Investigational Site Number 528033
city: Zutphen
country: Netherlands
facility: Investigational Site Number 528031
city: Zwolle
country: Netherlands
facility: Investigational Site Number 528020
city: Auckland
country: New Zealand
facility: Investigational Site Number 554010
city: Christchurch
country: New Zealand
facility: Investigational Site Number 554001
city: Dunedin
country: New Zealand
facility: Investigational Site Number 554006
city: Hamilton
country: New Zealand
facility: Investigational Site Number 554004
city: Lower Hutt
country: New Zealand
facility: Investigational Site Number 554011
city: Nelson
country: New Zealand
facility: Investigational Site Number 554005
city: New Plymouth
country: New Zealand
facility: Investigational Site Number 554007
city: Otahuhu
country: New Zealand
facility: Investigational Site Number 554002
city: Palmerston North
country: New Zealand
facility: Investigational Site Number 554008
city: Rotorua
country: New Zealand
facility: Investigational Site Number 554012
city: Takapuna
country: New Zealand
facility: Investigational Site Number 554009
city: Wellington
country: New Zealand
facility: Investigational Site Number 554003
city: Arendal
country: Norway
facility: Investigational Site Number 578004
city: Bergen
country: Norway
facility: Investigational Site Number 578013
city: Hamar
country: Norway
facility: Investigational Site Number 578009
city: Kongsvinger
country: Norway
facility: Investigational Site Number 578006
city: Oslo
country: Norway
facility: Investigational Site Number 578003
city: Oslo
country: Norway
facility: Investigational Site Number 578005
city: Stavanger
country: Norway
facility: Investigational Site Number 578012
city: Svelvik
country: Norway
facility: Investigational Site Number 578002
city: Tynset
country: Norway
facility: Investigational Site Number 578011
city: Arequipa
country: Peru
facility: Investigational Site Number 604018
city: Callao
country: Peru
facility: Investigational Site Number 604004
city: Callao
country: Peru
facility: Investigational Site Number 604025
city: Cuzco
country: Peru
facility: Investigational Site Number 604022
city: Ica
country: Peru
facility: Investigational Site Number 604013
city: Lima
country: Peru
facility: Investigational Site Number 604010
city: Lima
country: Peru
facility: Investigational Site Number 604008
city: Lima
country: Peru
facility: Investigational Site Number 604001
city: Lima
country: Peru
facility: Investigational Site Number 604007
city: Lima
country: Peru
facility: Investigational Site Number 604005
city: Lima
country: Peru
facility: Investigational Site Number 604006
city: Lima
country: Peru
facility: Investigational Site Number 604015
city: Lima
country: Peru
facility: Investigational Site Number 604016
city: Lima
country: Peru
facility: Investigational Site Number 604017
city: Lima
country: Peru
facility: Investigational Site Number 604019
city: Lima
country: Peru
facility: Investigational Site Number 604003
city: Lima
country: Peru
facility: Investigational Site Number 604024
city: Lima
country: Peru
facility: Investigational Site Number 604012
city: Piura
country: Peru
facility: Investigational Site Number 604020
city: Trujillo
country: Peru
facility: Investigational Site Number 604023
city: Cavite
country: Philippines
facility: Investigational Site Number 608012
city: Cebu City
country: Philippines
facility: Investigational Site Number 608003
city: Cebu City
country: Philippines
facility: Investigational Site Number 608013
city: Davao City
country: Philippines
facility: Investigational Site Number 608011
city: Davao
country: Philippines
facility: Investigational Site Number 608010
city: Iloilo City
country: Philippines
facility: Investigational Site Number 608006
city: Makati City
country: Philippines
facility: Investigational Site Number 608002
city: Manila
country: Philippines
facility: Investigational Site Number 608004
city: Manila
country: Philippines
facility: Investigational Site Number 608014
city: Quezon City
country: Philippines
facility: Investigational Site Number 608001
city: Quezon City
country: Philippines
facility: Investigational Site Number 608009
city: Quezon
country: Philippines
facility: Investigational Site Number 608005
city: San Juan
country: Philippines
facility: Investigational Site Number 608008
city: Bydgoszcz
country: Poland
facility: Investigational Site Number 616026
city: Bydgoszcz
country: Poland
facility: Investigational Site Number 616029
city: Chrzanow
country: Poland
facility: Investigational Site Number 616010
city: Czeladz
country: Poland
facility: Investigational Site Number 616036
city: Gdansk
country: Poland
facility: Investigational Site Number 616034
city: Gdansk
country: Poland
facility: Investigational Site Number 616015
city: Gdynia
country: Poland
facility: Investigational Site Number 616035
city: Gdynia
country: Poland
facility: Investigational Site Number 616005
city: Gdynia
country: Poland
facility: Investigational Site Number 616033
city: Grodzisk Mazowiecki
country: Poland
facility: Investigational Site Number 616037
city: Jelenia Gora
country: Poland
facility: Investigational Site Number 616030
city: Krakow
country: Poland
facility: Investigational Site Number 616031
city: Krakow
country: Poland
facility: Investigational Site Number 616002
city: Leczna
country: Poland
facility: Investigational Site Number 616012
city: Legnica
country: Poland
facility: Investigational Site Number 616017
city: Lodz
country: Poland
facility: Investigational Site Number 616019
city: Lubin
country: Poland
facility: Investigational Site Number 616016
city: Olawa
country: Poland
facility: Investigational Site Number 616021
city: Olsztyn
country: Poland
facility: Investigational Site Number 616039
city: Plock
country: Poland
facility: Investigational Site Number 616003
city: Poznan
country: Poland
facility: Investigational Site Number 616011
city: Pulawy
country: Poland
facility: Investigational Site Number 616018
city: Skierniewice
country: Poland
facility: Investigational Site Number 616006
city: Sobotka
country: Poland
facility: Investigational Site Number 616027
city: Sokolka
country: Poland
facility: Investigational Site Number 616007
city: Swidnik
country: Poland
facility: Investigational Site Number 616022
city: Szczecin
country: Poland
facility: Investigational Site Number 616024
city: Torun
country: Poland
facility: Investigational Site Number 616004
city: Torun
country: Poland
facility: Investigational Site Number 616013
city: Torun
country: Poland
facility: Investigational Site Number 616025
city: W?Grów
country: Poland
facility: Investigational Site Number 616032
city: Warszawa
country: Poland
facility: Investigational Site Number 616040
city: Warszawa
country: Poland
facility: Investigational Site Number 616020
city: Warszawa
country: Poland
facility: Investigational Site Number 616038
city: Warszawa
country: Poland
facility: Investigational Site Number 616008
city: Wroclaw
country: Poland
facility: Investigational Site Number 616041
city: Almada
country: Portugal
facility: Investigational Site Number 620004
city: Aveiro
country: Portugal
facility: Investigational Site Number 620005
city: Coimbra
country: Portugal
facility: Investigational Site Number 620011
city: Coimbra
country: Portugal
facility: Investigational Site Number 620008
city: Leiria
country: Portugal
facility: Investigational Site Number 620001
city: Ponta Delgada
country: Portugal
facility: Investigational Site Number 620003
city: Setubal
country: Portugal
facility: Investigational Site Number 620002
city: Vila Franca De Xira
country: Portugal
facility: Investigational Site Number 620010
city: Vila Nova Gaia
country: Portugal
facility: Investigational Site Number 620006
city: Braila
country: Romania
facility: Investigational Site Number 642001
city: Bucharest
country: Romania
facility: Investigational Site Number 642003
city: Bucuresti
country: Romania
facility: Investigational Site Number 642012
city: Bucuresti
country: Romania
facility: Investigational Site Number 642021
city: Bucuresti
country: Romania
facility: Investigational Site Number 642007
city: Bucuresti
country: Romania
facility: Investigational Site Number 642008
city: Buzau
country: Romania
facility: Investigational Site Number 642005
city: Codlea
country: Romania
facility: Investigational Site Number 642013
city: Constanta
country: Romania
facility: Investigational Site Number 642004
city: Craiova
country: Romania
facility: Investigational Site Number 642002
city: Craiova
country: Romania
facility: Investigational Site Number 642016
city: Focsani
country: Romania
facility: Investigational Site Number 642010
city: Iasi
country: Romania
facility: Investigational Site Number 642017
city: Targoviste
country: Romania
facility: Investigational Site Number 642006
city: Targu Mures
country: Romania
facility: Investigational Site Number 642019
city: Targu Mures
country: Romania
facility: Investigational Site Number 642015
city: Timisoara
country: Romania
facility: Investigational Site Number 642018
city: Barnaul
country: Russian Federation
facility: Investigational Site Number 643027
city: Kazan
country: Russian Federation
facility: Investigational Site Number 643037
city: Kemerovo
country: Russian Federation
facility: Investigational Site Number 643013
city: Krasnodar
country: Russian Federation
facility: Investigational Site Number 643020
city: Krasnodar
country: Russian Federation
facility: Investigational Site Number 643053
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643033
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643002
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643011
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643029
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643028
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643004
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643016
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643023
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643044
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643022
city: Moscow
country: Russian Federation
facility: Investigational Site Number 643031
city: Nizhny Novgorod
country: Russian Federation
facility: Investigational Site Number 643043
city: Novosibirsk
country: Russian Federation
facility: Investigational Site Number 643034
city: Novosibirsk
country: Russian Federation
facility: Investigational Site Number 643052
city: Novosibirsk
country: Russian Federation
facility: Investigational Site Number 643050
city: Omsk
country: Russian Federation
facility: Investigational Site Number 643035
city: Perm
country: Russian Federation
facility: Investigational Site Number 643039
city: Rostov-Na-Donu
country: Russian Federation
facility: Investigational Site Number 643008
city: Ryazan
country: Russian Federation
facility: Investigational Site Number 643017
city: Saint - Petersburg
country: Russian Federation
facility: Investigational Site Number 643006
city: Saint - Petersburg
country: Russian Federation
facility: Investigational Site Number 643015
city: Saint Petersburg
country: Russian Federation
facility: Investigational Site Number 643001
city: Saint Petersburg
country: Russian Federation
facility: Investigational Site Number 643007
city: Saint-Petersburg
country: Russian Federation
facility: Investigational Site Number 643051
city: Saint-Petersburg
country: Russian Federation
facility: Investigational Site Number 643042
city: Saint-Petersburg
country: Russian Federation
facility: Investigational Site Number 643040
city: Saratov
country: Russian Federation
facility: Investigational Site Number 643012
city: Saratov
country: Russian Federation
facility: Investigational Site Number 643021
city: Saratov
country: Russian Federation
facility: Investigational Site Number 643003
city: Saratov
country: Russian Federation
facility: Investigational Site Number 643014
city: St-Petersburg
country: Russian Federation
facility: Investigational Site Number 643030
city: St-Petersburg
country: Russian Federation
facility: Investigational Site Number 643010
city: St-Petersburg
country: Russian Federation
facility: Investigational Site Number 643054
city: Tomsk
country: Russian Federation
facility: Investigational Site Number 643049
city: Tyumen
country: Russian Federation
facility: Investigational Site Number 643019
city: Tyumen
country: Russian Federation
facility: Investigational Site Number 643025
city: Voronezh
country: Russian Federation
facility: Investigational Site Number 643045
city: Yaroslavl
country: Russian Federation
facility: Investigational Site Number 643009
city: Belgrade
country: Serbia
facility: Investigational Site Number 688003
city: Belgrade
country: Serbia
facility: Investigational Site Number 688005
city: Belgrade
country: Serbia
facility: Investigational Site Number 688006
city: Belgrade
country: Serbia
facility: Investigational Site Number 688007
city: Belgrade
country: Serbia
facility: Investigational Site Number 688008
city: Belgrade
country: Serbia
facility: Investigational Site Number 688010
city: Belgrade
country: Serbia
facility: Investigational Site Number 688011
city: Belgrade
country: Serbia
facility: Investigational Site Number 688013
city: Belgrade
country: Serbia
facility: Investigational Site Number 688015
city: Belgrade
country: Serbia
facility: Investigational Site Number 688002
city: Kragujevac
country: Serbia
facility: Investigational Site Number 688012
city: Leskovac
country: Serbia
facility: Investigational Site Number 688016
city: Niska Banja
country: Serbia
facility: Investigational Site Number 688001
city: Nis
country: Serbia
facility: Investigational Site Number 688004
city: Pancevo
country: Serbia
facility: Investigational Site Number 688018
city: Sremska Kamenica
country: Serbia
facility: Investigational Site Number 688009
city: Sremska Mitrovica
country: Serbia
facility: Investigational Site Number 688017
city: Valjevo
country: Serbia
facility: Investigational Site Number 688014
city: Singapore
country: Singapore
facility: Investigational Site Number 702002
city: Singapore
country: Singapore
facility: Investigational Site Number 702003
city: Singapore
country: Singapore
facility: Investigational Site Number 702001
city: Bardejov
country: Slovakia
facility: Investigational Site Number 703001
city: Bratislava
country: Slovakia
facility: Investigational Site Number 703008
city: Bratislava
country: Slovakia
facility: Investigational Site Number 703020
city: Bratislava
country: Slovakia
facility: Investigational Site Number 703014
city: Bratislava
country: Slovakia
facility: Investigational Site Number 703013
city: Dolny Kubin
country: Slovakia
facility: Investigational Site Number 703023
city: Kosice
country: Slovakia
facility: Investigational Site Number 703002
city: Kosice
country: Slovakia
facility: Investigational Site Number 703009
city: Kosice
country: Slovakia
facility: Investigational Site Number 703016
city: Kosice
country: Slovakia
facility: Investigational Site Number 703019
city: Kosice
country: Slovakia
facility: Investigational Site Number 703007
city: Kralovsky Chlmec
country: Slovakia
facility: Investigational Site Number 703012
city: Lucenec
country: Slovakia
facility: Investigational Site Number 703006
city: Lucenec
country: Slovakia
facility: Investigational Site Number 703010
city: Nitra
country: Slovakia
facility: Investigational Site Number 703003
city: Presov
country: Slovakia
facility: Investigational Site Number 703004
city: Svidnik
country: Slovakia
facility: Investigational Site Number 703018
city: Trebisov
country: Slovakia
facility: Investigational Site Number 703022
city: Zilina
country: Slovakia
facility: Investigational Site Number 703005
city: Celje
country: Slovenia
facility: Investigational Site Number 705001
city: Izola
country: Slovenia
facility: Investigational Site Number 705004
city: Jesenice
country: Slovenia
facility: Investigational Site Number 705002
city: Ljubljana
country: Slovenia
facility: Investigational Site Number 705005
city: Ljubljana
country: Slovenia
facility: Investigational Site Number 705006
city: Alberton
country: South Africa
facility: Investigational Site Number 710017
city: Bellville
country: South Africa
facility: Investigational Site Number 710007
city: Bloemfontein
country: South Africa
facility: Investigational Site Number 710015
city: Cape Town
country: South Africa
facility: Investigational Site Number 710009
city: Cape Town
country: South Africa
facility: Investigational Site Number 710010
city: Chatsworth
country: South Africa
facility: Investigational Site Number 710005
city: Durban
country: South Africa
facility: Investigational Site Number 710006
city: Durban
country: South Africa
facility: Investigational Site Number 710004
city: Durban
country: South Africa
facility: Investigational Site Number 710002
city: Johannesburg
country: South Africa
facility: Investigational Site Number 710012
city: Johannesburg
country: South Africa
facility: Investigational Site Number 710014
city: Kempton Park
country: South Africa
facility: Investigational Site Number 710019
city: Kimberley
country: South Africa
facility: Investigational Site Number 710011
city: Kuils River
country: South Africa
facility: Investigational Site Number 710021
city: Parow
country: South Africa
facility: Investigational Site Number 710018
city: Pretoria
country: South Africa
facility: Investigational Site Number 710008
city: Pretoria
country: South Africa
facility: Investigational Site Number 710016
city: Stellenbosch
country: South Africa
facility: Investigational Site Number 710020
city: Tongaat
country: South Africa
facility: Investigational Site Number 710013
city: Western Cape
country: South Africa
facility: Investigational Site Number 710022
city: Worcester
country: South Africa
facility: Investigational Site Number 710003
city: Alcalá De Henares
country: Spain
facility: Investigational Site Number 724010
city: Almería
country: Spain
facility: Investigational Site Number 724007
city: Barcelona
country: Spain
facility: Investigational Site Number 724037
city: Barcelona
country: Spain
facility: Investigational Site Number 724041
city: Barcelona
country: Spain
facility: Investigational Site Number 724038
city: Barcelona
country: Spain
facility: Investigational Site Number 724008
city: Cáceres
country: Spain
facility: Investigational Site Number 724039
city: Córdoba
country: Spain
facility: Investigational Site Number 724042
city: Fuenlabrada
country: Spain
facility: Investigational Site Number 724027
city: Girona
country: Spain
facility: Investigational Site Number 724002
city: Granada
country: Spain
facility: Investigational Site Number 724013
city: Guadalajara
country: Spain
facility: Investigational Site Number 724032
city: Hospitalet De Llobregat
country: Spain
facility: Investigational Site Number 724025
city: Huelva
country: Spain
facility: Investigational Site Number 724003
city: León
country: Spain
facility: Investigational Site Number 724021
city: Lleida
country: Spain
facility: Investigational Site Number 724026
city: Lugo
country: Spain
facility: Investigational Site Number 724006
city: Madrid
country: Spain
facility: Investigational Site Number 724030
city: Madrid
country: Spain
facility: Investigational Site Number 724020
city: Madrid
country: Spain
facility: Investigational Site Number 724015
city: Madrid
country: Spain
facility: Investigational Site Number 724031
city: Madrid
country: Spain
facility: Investigational Site Number 724033
city: Madrid
country: Spain
facility: Investigational Site Number 724017
city: Majadahonda
country: Spain
facility: Investigational Site Number 724035
city: Murcia
country: Spain
facility: Investigational Site Number 724036
city: Málaga
country: Spain
facility: Investigational Site Number 724016
city: Málaga
country: Spain
facility: Investigational Site Number 724043
city: Oviedo
country: Spain
facility: Investigational Site Number 724001
city: Sabadell
country: Spain
facility: Investigational Site Number 724022
city: San Sebastian De Los Reyes
country: Spain
facility: Investigational Site Number 724029
city: Santander
country: Spain
facility: Investigational Site Number 724028
city: Santiago De Compostela
country: Spain
facility: Investigational Site Number 724034
city: Sevilla
country: Spain
facility: Investigational Site Number 724014
city: Tarragona
country: Spain
facility: Investigational Site Number 724024
city: Valencia
country: Spain
facility: Investigational Site Number 724019
city: Valencia
country: Spain
facility: Investigational Site Number 724009
city: Valencia
country: Spain
facility: Investigational Site Number 724011
city: Valladolid
country: Spain
facility: Investigational Site Number 724023
city: Vigo
country: Spain
facility: Investigational Site Number 724005
city: Zaragoza
country: Spain
facility: Investigational Site Number 724040
city: Colombo 7
country: Sri Lanka
facility: Investigational Site Number 144002
city: Colombo 8
country: Sri Lanka
facility: Investigational Site Number 144004
city: Colombo
country: Sri Lanka
facility: Investigational Site Number 144003
city: Colombo
country: Sri Lanka
facility: Investigational Site Number 144010
city: Colombo
country: Sri Lanka
facility: Investigational Site Number 144005
city: Colombo
country: Sri Lanka
facility: Investigational Site Number 144006
city: Colombo
country: Sri Lanka
facility: Investigational Site Number 144001
city: Kandy
country: Sri Lanka
facility: Investigational Site Number 144008
city: Kurunegala
country: Sri Lanka
facility: Investigational Site Number 144009
city: Ragama
country: Sri Lanka
facility: Investigational Site Number 144007
city: Falun
country: Sweden
facility: Investigational Site Number 752001
city: Göteborg
country: Sweden
facility: Investigational Site Number 752016
city: Halmstad
country: Sweden
facility: Investigational Site Number 752011
city: Karlshamn
country: Sweden
facility: Investigational Site Number 752006
city: Karlskrona
country: Sweden
facility: Investigational Site Number 752008
city: Kristianstad
country: Sweden
facility: Investigational Site Number 752004
city: Köping
country: Sweden
facility: Investigational Site Number 752013
city: Malmö
country: Sweden
facility: Investigational Site Number 752015
city: Mölndal
country: Sweden
facility: Investigational Site Number 752012
city: Stockholm
country: Sweden
facility: Investigational Site Number 752009
city: Stockholm
country: Sweden
facility: Investigational Site Number 752002
city: Sundsvall
country: Sweden
facility: Investigational Site Number 752014
city: Uppsala
country: Sweden
facility: Investigational Site Number 752007
city: Basel
country: Switzerland
facility: Investigational Site Number 756005
city: Geneve
country: Switzerland
facility: Investigational Site Number 756003
city: Lugano
country: Switzerland
facility: Investigational Site Number 756004
city: Zürich
country: Switzerland
facility: Investigational Site Number 756002
city: Changhua
country: Taiwan
facility: Investigational Site Number 158003
city: Division Of Cardiology
country: Taiwan
facility: Investigational Site Number 158008
city: Hsinchu
country: Taiwan
facility: Investigational Site Number 158014
city: Kaohsiung
country: Taiwan
facility: Investigational Site Number 158013
city: Taichung
country: Taiwan
facility: Investigational Site Number 158004
city: Tainan
country: Taiwan
facility: Investigational Site Number 158009
city: Tainan
country: Taiwan
facility: Investigational Site Number 158011
city: Taipei
country: Taiwan
facility: Investigational Site Number 158005
city: Taipei
country: Taiwan
facility: Investigational Site Number 158001
city: Taipei
country: Taiwan
facility: Investigational Site Number 158010
city: Taipei
country: Taiwan
facility: Investigational Site Number 158007
city: Taoyuan Hsien
country: Taiwan
facility: Investigational Site Number 158012
city: Yunlin
country: Taiwan
facility: Investigational Site Number 158002
city: Bangkok-Noi
country: Thailand
facility: Investigational Site Number 764009
city: Bangkok
country: Thailand
facility: Investigational Site Number 764001
city: Bangkok
country: Thailand
facility: Investigational Site Number 764011
city: Bangkok
country: Thailand
facility: Investigational Site Number 764007
city: Bangkok
country: Thailand
facility: Investigational Site Number 764012
city: Hat Yai
country: Thailand
facility: Investigational Site Number 764005
city: Klong Luang
country: Thailand
facility: Investigational Site Number 764008
city: Moung
country: Thailand
facility: Investigational Site Number 764002
city: Muang
country: Thailand
facility: Investigational Site Number 764003
city: Nonthaburi
country: Thailand
facility: Investigational Site Number 764010
city: Pratumwan
country: Thailand
facility: Investigational Site Number 764006
city: Adana
country: Turkey
facility: Investigational Site Number 792007
city: Ankara
country: Turkey
facility: Investigational Site Number 792009
city: Bursa
country: Turkey
facility: Investigational Site Number 792006
city: Eskisehir
country: Turkey
facility: Investigational Site Number 792016
city: Istanbul
country: Turkey
facility: Investigational Site Number 792014
city: Istanbul
country: Turkey
facility: Investigational Site Number 792005
city: Istanbul
country: Turkey
facility: Investigational Site Number 792011
city: Istanbul
country: Turkey
facility: Investigational Site Number 792013
city: Izmir
country: Turkey
facility: Investigational Site Number 792004
city: Izmir
country: Turkey
facility: Investigational Site Number 792003
city: Kocaeli
country: Turkey
facility: Investigational Site Number 792015
city: Mersin
country: Turkey
facility: Investigational Site Number 792010
city: Chernivtsi
country: Ukraine
facility: Investigational Site Number 804015
city: Dnipropetrovsk
country: Ukraine
facility: Investigational Site Number 804018
city: Donetsk
country: Ukraine
facility: Investigational Site Number 804027
city: Donetsk
country: Ukraine
facility: Investigational Site Number 804012
city: Ivano-Frankivsk
country: Ukraine
facility: Investigational Site Number 804010
city: Kharkiv
country: Ukraine
facility: Investigational Site Number 804006
city: Kharkiv
country: Ukraine
facility: Investigational Site Number 804003
city: Kharkiv
country: Ukraine
facility: Investigational Site Number 804009
city: Khmelnytskyi
country: Ukraine
facility: Investigational Site Number 804020
city: Kiev
country: Ukraine
facility: Investigational Site Number 804001
city: Kiev
country: Ukraine
facility: Investigational Site Number 804002
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804011
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804014
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804025
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804034
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804036
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804016
city: Kyiv
country: Ukraine
facility: Investigational Site Number 804030
city: Lutsk
country: Ukraine
facility: Investigational Site Number 804028
city: Lviv
country: Ukraine
facility: Investigational Site Number 804033
city: Lviv
country: Ukraine
facility: Investigational Site Number 804031
city: Mykolaiv
country: Ukraine
facility: Investigational Site Number 804029
city: Odesa
country: Ukraine
facility: Investigational Site Number 804013
city: Odessa
country: Ukraine
facility: Investigational Site Number 804004
city: Simferopol
country: Ukraine
facility: Investigational Site Number 804017
city: Sumy
country: Ukraine
facility: Investigational Site Number 804035
city: Uzhgorod
country: Ukraine
facility: Investigational Site Number 804007
city: Vinnitsya
country: Ukraine
facility: Investigational Site Number 804005
city: Vinnytsia
country: Ukraine
facility: Investigational Site Number 804008
city: Zaporizhia
country: Ukraine
facility: Investigational Site Number 804026
city: Zhytomyr
country: Ukraine
facility: Investigational Site Number 804024
city: Zhytomyr
country: Ukraine
facility: Investigational Site Number 804032
city: Basildon
country: United Kingdom
facility: Investigational Site Number 826018
city: Birmingham
country: United Kingdom
facility: Investigational Site Number 826015
city: Birmingham
country: United Kingdom
facility: Investigational Site Number 826030
city: Bournemouth
country: United Kingdom
facility: Investigational Site Number 826038
city: Bradford
country: United Kingdom
facility: Investigational Site Number 826025
city: Burton On Trent
country: United Kingdom
facility: Investigational Site Number 826027
city: Cardiff
country: United Kingdom
facility: Investigational Site Number 826017
city: Chertsey
country: United Kingdom
facility: Investigational Site Number 826010
city: Chesterfield
country: United Kingdom
facility: Investigational Site Number 826012
city: Chichester
country: United Kingdom
facility: Investigational Site Number 826039
city: Cumbria
country: United Kingdom
facility: Investigational Site Number 826024
city: Dudley
country: United Kingdom
facility: Investigational Site Number 826041
city: Harrow
country: United Kingdom
facility: Investigational Site Number 826021
city: High Wycombe
country: United Kingdom
facility: Investigational Site Number 826026
city: Hull
country: United Kingdom
facility: Investigational Site Number 826028
city: London
country: United Kingdom
facility: Investigational Site Number 826034
city: Manchester
country: United Kingdom
facility: Investigational Site Number 826004
city: Newcastle Upon Tyne
country: United Kingdom
facility: Investigational Site Number 826011
city: Northampton
country: United Kingdom
facility: Investigational Site Number 826036
city: Peterborough
country: United Kingdom
facility: Investigational Site Number 826019
city: Plymouth
country: United Kingdom
facility: Investigational Site Number 826020
city: Portadown
country: United Kingdom
facility: Investigational Site Number 826040
city: Portsmouth
country: United Kingdom
facility: Investigational Site Number 826016
city: Redhill
country: United Kingdom
facility: Investigational Site Number 826014
city: Rhyl
country: United Kingdom
facility: Investigational Site Number 826007
city: Romford
country: United Kingdom
facility: Investigational Site Number 826001
city: Rotherham
country: United Kingdom
facility: Investigational Site Number 826009
city: Sheffield
country: United Kingdom
facility: Investigational Site Number 826002
city: South Shields
country: United Kingdom
facility: Investigational Site Number 826032
city: St Leonards
country: United Kingdom
facility: Investigational Site Number 826013
city: Stoke-On-Trent
country: United Kingdom
facility: Investigational Site Number 826005
city: Sunderland
country: United Kingdom
facility: Investigational Site Number 826031
city: Truro
country: United Kingdom
facility: Investigational Site Number 826022
city: Wigan
country: United Kingdom
facility: Investigational Site Number 826035
city: Worcester
country: United Kingdom
facility: Investigational Site Number 826003
Study officials:
affiliation: Sanofi
name: Clinical Sciences & Operations
role: STUDY_DIRECTOR
References:
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citation: Landmesser U, McGinniss J, Steg PG, Bhatt DL, Bittner VA, Diaz R, Dilic M, Goodman SG, Jukema JW, Loy M, Pecin I, Pordy R, Poulsen SH, Szarek M, White HD, Schwartz GG; ODYSSEY OUTCOMES Investigators. Achievement of ESC/EAS LDL-C treatment goals after an acute coronary syndrome with statin and alirocumab. Eur J Prev Cardiol. 2022 Oct 20;29(14):1842-1851. doi: 10.1093/eurjpc/zwac107.
citation: Chiang CE, Schwartz GG, Elbez Y, Szarek M, Bhatt DL, Bittner VA, Diaz R, Erglis A, Goodman SG, Hagstrom E, Jukema JW, Liberopoulos E, Loy M, Pordy R, White HD, Simon T, Steg PG; ODYSSEY OUTCOMES Investigators. Alirocumab and Cardiovascular Outcomes in Patients With Previous Myocardial Infarction: Prespecified Subanalysis From ODYSSEY OUTCOMES. Can J Cardiol. 2022 Oct;38(10):1542-1549. doi: 10.1016/j.cjca.2022.05.021. Epub 2022 May 27.
citation: Ostadal P, Steg PG, Poulouin Y, Bhatt DL, Bittner VA, Chua T, Diaz R, Goodman SG, Huo Y, Jukema JW, Karpov Y, Pordy R, Scemama M, Szarek M, White HD, Schwartz GG; ODYSSEY OUTCOMES Investigators. Metabolic risk factors and effect of alirocumab on cardiovascular events after acute coronary syndrome: a post-hoc analysis of the ODYSSEY OUTCOMES randomised controlled trial. Lancet Diabetes Endocrinol. 2022 May;10(5):330-340. doi: 10.1016/S2213-8587(22)00043-2. Epub 2022 Apr 1.
citation: Lopes RD, Guimaraes PO, Schwartz GG, Bhatt DL, Bittner VA, Budaj A, Dalby AJ, Diaz R, Goodman SG, Harrington RA, Jukema JW, Kiss RG, Loy M, Pordy R, Poulouin Y, Szarek M, White HD, Steg PG; ODYSSEY OUTCOMES Investigators. Effect of Alirocumab on Incidence of Atrial Fibrillation After Acute Coronary Syndromes: Insights from the ODYSSEY OUTCOMES Trial. Am J Med. 2022 Jul;135(7):915-918. doi: 10.1016/j.amjmed.2022.02.016. Epub 2022 Mar 14.
citation: Schwartz GG, Szarek M, Bittner VA, Diaz R, Goodman SG, Jukema JW, Landmesser U, Lopez-Jaramillo P, Manvelian G, Pordy R, Scemama M, Sinnaeve PR, White HD, Gabriel Steg P; ODYSSEY Outcomes Committees and Investigators. Lipoprotein(a) and Benefit of PCSK9 Inhibition in Patients With Nominally Controlled LDL Cholesterol. J Am Coll Cardiol. 2021 Aug 3;78(5):421-433. doi: 10.1016/j.jacc.2021.04.102.
citation: Diaz R, Li QH, Bhatt DL, Bittner VA, Baccara-Dinet MT, Goodman SG, Jukema JW, Kimura T, Parkhomenko A, Pordy R, Reiner Z, Roe MT, Szarek M, Tse HF, White HD, Zahger D, Zeiher AM, Schwartz GG, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Intensity of statin treatment after acute coronary syndrome, residual risk, and its modification by alirocumab: insights from the ODYSSEY OUTCOMES trial. Eur J Prev Cardiol. 2021 Mar 23;28(1):33-43. doi: 10.1177/2047487320941987. Epub 2020 Jul 27.
citation: Schwartz GG, Szarek M, Bittner VA, Bhatt DL, Diaz R, Goodman SG, Jukema JW, Loy M, Manvelian G, Pordy R, White HD, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Relation of Lipoprotein(a) Levels to Incident Type 2 Diabetes and Modification by Alirocumab Treatment. Diabetes Care. 2021 May;44(5):1219-1227. doi: 10.2337/dc20-2842. Epub 2021 Mar 15.
citation: Schwartz GG, Gabriel Steg P, Bhatt DL, Bittner VA, Diaz R, Goodman SG, Jukema JW, Kim YU, Li QH, Manvelian G, Pordy R, Sourdille T, White HD, Szarek M; ODYSSEY OUTCOMES Committees and Investigators. Clinical Efficacy and Safety of Alirocumab After Acute Coronary Syndrome According to Achieved Level of Low-Density Lipoprotein Cholesterol: A Propensity Score-Matched Analysis of the ODYSSEY OUTCOMES Trial. Circulation. 2021 Mar 16;143(11):1109-1122. doi: 10.1161/CIRCULATIONAHA.120.049447. Epub 2021 Jan 13.
citation: Schmidt AF, Carter JL, Pearce LS, Wilkins JT, Overington JP, Hingorani AD, Casas JP. PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2020 Oct 20;10(10):CD011748. doi: 10.1002/14651858.CD011748.pub3.
citation: Szarek M, Bittner VA, Aylward P, Baccara-Dinet M, Bhatt DL, Diaz R, Fras Z, Goodman SG, Halvorsen S, Harrington RA, Jukema JW, Moriarty PM, Pordy R, Ray KK, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG; ODYSSEY OUTCOMES Investigators. Lipoprotein(a) lowering by alirocumab reduces the total burden of cardiovascular events independent of low-density lipoprotein cholesterol lowering: ODYSSEY OUTCOMES trial. Eur Heart J. 2020 Nov 21;41(44):4245-4255. doi: 10.1093/eurheartj/ehaa649.
citation: Bhatt DL, Briggs AH, Reed SD, Annemans L, Szarek M, Bittner VA, Diaz R, Goodman SG, Harrington RA, Higuchi K, Joulain F, Jukema JW, Li QH, Mahaffey KW, Sanchez RJ, Roe MT, Lopes RD, White HD, Zeiher AM, Schwartz GG, Gabriel Steg P; ODYSSEY OUTCOMES Investigators. Cost-Effectiveness of Alirocumab in Patients With Acute Coronary Syndromes: The ODYSSEY OUTCOMES Trial. J Am Coll Cardiol. 2020 May 12;75(18):2297-2308. doi: 10.1016/j.jacc.2020.03.029.
citation: Schwartz GG, Steg PG, Szarek M, Bittner VA, Diaz R, Goodman SG, Kim YU, Jukema JW, Pordy R, Roe MT, White HD, Bhatt DL; ODYSSEY OUTCOMES Committees and Investigators*. Peripheral Artery Disease and Venous Thromboembolic Events After Acute Coronary Syndrome: Role of Lipoprotein(a) and Modification by Alirocumab: Prespecified Analysis of the ODYSSEY OUTCOMES Randomized Clinical Trial. Circulation. 2020 May 19;141(20):1608-1617. doi: 10.1161/CIRCULATIONAHA.120.046524. Epub 2020 Mar 29.
citation: Bittner VA, Szarek M, Aylward PE, Bhatt DL, Diaz R, Edelberg JM, Fras Z, Goodman SG, Halvorsen S, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Moriarty PM, Moryusef A, Pordy R, Roe MT, Sinnaeve P, Tsimikas S, Vogel R, White HD, Zahger D, Zeiher AM, Steg PG, Schwartz GG; ODYSSEY OUTCOMES Committees and Investigators. Effect of Alirocumab on Lipoprotein(a) and Cardiovascular Risk After Acute Coronary Syndrome. J Am Coll Cardiol. 2020 Jan 21;75(2):133-144. doi: 10.1016/j.jacc.2019.10.057.
citation: Szarek M, Steg PG, DiCenso D, Bhatt DL, Bittner VA, Budaj A, Diaz R, Goodman SG, Gotcheva N, Jukema JW, Pordy R, Roe MT, Sourdille T, White HD, Xavier D, Zeiher AM, Schwartz GG. Alirocumab Reduces Total Hospitalizations and Increases Days Alive and Out of Hospital in the ODYSSEY OUTCOMES Trial. Circ Cardiovasc Qual Outcomes. 2019 Nov;12(11):e005858. doi: 10.1161/CIRCOUTCOMES.119.005858. Epub 2019 Nov 11.
citation: Jukema JW, Zijlstra LE, Bhatt DL, Bittner VA, Diaz R, Drexel H, Goodman SG, Kim YU, Pordy R, Reiner Z, Roe MT, Tse HF, Montenegro Valdovinos PC, White HD, Zeiher AM, Szarek M, Schwartz GG, Steg PG; ODYSSEY OUTCOMES Investigators. Effect of Alirocumab on Stroke in ODYSSEY OUTCOMES. Circulation. 2019 Dec 17;140(25):2054-2062. doi: 10.1161/CIRCULATIONAHA.119.043826. Epub 2019 Nov 11.
citation: Roe MT, Li QH, Bhatt DL, Bittner VA, Diaz R, Goodman SG, Harrington RA, Jukema JW, Lopez-Jaramillo P, Lopes RD, Louie MJ, Moriarty PM, Szarek M, Vogel R, White HD, Zeiher AM, Baccara-Dinet MT, Steg PG, Schwartz GG. Risk Categorization Using New American College of Cardiology/American Heart Association Guidelines for Cholesterol Management and Its Relation to Alirocumab Treatment Following Acute Coronary Syndromes. Circulation. 2019 Nov 5;140(19):1578-1589. doi: 10.1161/CIRCULATIONAHA.119.042551. Epub 2019 Sep 2.
citation: Goodman SG, Aylward PE, Szarek M, Chumburidze V, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Hanotin C, Harrington RA, Jukema JW, Kedev S, Letierce A, Moryusef A, Pordy R, Ramos Lopez GA, Roe MT, Viigimaa M, White HD, Zeiher AM, Steg PG, Schwartz GG; ODYSSEY OUTCOMES Committees and Investigators. Effects of Alirocumab on Cardiovascular Events After Coronary Bypass Surgery. J Am Coll Cardiol. 2019 Sep 3;74(9):1177-1186. doi: 10.1016/j.jacc.2019.07.015.
citation: Ray KK, Colhoun HM, Szarek M, Baccara-Dinet M, Bhatt DL, Bittner VA, Budaj AJ, Diaz R, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Lopes RD, Moryusef A, Murin J, Pordy R, Ristic AD, Roe MT, Tunon J, White HD, Zeiher AM, Schwartz GG, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial. Lancet Diabetes Endocrinol. 2019 Aug;7(8):618-628. doi: 10.1016/S2213-8587(19)30158-5. Epub 2019 Jul 1.
citation: Steg PG, Szarek M, Bhatt DL, Bittner VA, Bregeault MF, Dalby AJ, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Ostadal P, Parkhomenko A, Pordy R, Roe MT, Tricoci P, Vogel R, White HD, Zeiher AM, Schwartz GG. Effect of Alirocumab on Mortality After Acute Coronary Syndromes. Circulation. 2019 Jul 9;140(2):103-112. doi: 10.1161/CIRCULATIONAHA.118.038840. Epub 2019 May 23.
citation: Jukema JW, Szarek M, Zijlstra LE, de Silva HA, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Karpov Y, Moryusef A, Pordy R, Prieto JC, Roe MT, White HD, Zeiher AM, Schwartz GG, Steg PG; ODYSSEY OUTCOMES Committees and Investigators. Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome: ODYSSEY OUTCOMES Trial. J Am Coll Cardiol. 2019 Sep 3;74(9):1167-1176. doi: 10.1016/j.jacc.2019.03.013. Epub 2019 Mar 18.
citation: Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, Edelberg JM, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Lecorps G, Mahaffey KW, Moryusef A, Pordy R, Quintero K, Roe MT, Sasiela WJ, Tamby JF, Tricoci P, White HD, Zeiher AM; ODYSSEY OUTCOMES Committees and Investigators. Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome. N Engl J Med. 2018 Nov 29;379(22):2097-2107. doi: 10.1056/NEJMoa1801174. Epub 2018 Nov 7.
citation: Schwartz GG, Bessac L, Berdan LG, Bhatt DL, Bittner V, Diaz R, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Mahaffey KW, Moryusef A, Pordy R, Roe MT, Rorick T, Sasiela WJ, Shirodaria C, Szarek M, Tamby JF, Tricoci P, White H, Zeiher A, Steg PG. Effect of alirocumab, a monoclonal antibody to PCSK9, on long-term cardiovascular outcomes following acute coronary syndromes: rationale and design of the ODYSSEY outcomes trial. Am Heart J. 2014 Nov;168(5):682-9. doi: 10.1016/j.ahj.2014.07.028. Epub 2014 Aug 7.