Clinical trial NCT01305603: Ultrasound-guided Dual TAP Block: Magnetic Resonance (MR) Evaluation of the Distribution of Local Anesthetic
Official title: Dual TAP Block Characteristics - Evaluation of Local Anesthetic Distribution by MR Scanning
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pain, Postoperative
Lead sponsor: Bispebjerg Hospital
Sponsor class: OTHER
First posted: 2011-03-01
Enrollment: 10
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Using Magnetic resonance (MR) scanning and ultrasonography the investigators wish to investigate, in what way a known volume of local anesthetic injectate will be distributed in the transverse abdominis plane (TAP) in young healthy male volunteers. The investigators compare the anatomical distribution of the local anesthetic injectate in the TAP when performing an ultrasound-guided classical TAP block and a Dual TAP block. The investigators also want to compare the spread of anesthetized frontal dermatomes when performing an ultrasound-guided classical TAP block and a Dual TAP block.

Detailed description: There has been much debate as to what extent the classical TAP block will anesthetize more than the frontal dermatomes (TH10-Th12/L1). Some cadaver studies have been performed with injection of dye in the classical TAP. However, it is still not clear whether a single injection of local anesthetic in the classical TAP block position will reach the more cephalad and medial intercostal TAP plexus (Th6-Th9). In this study the investigators use MR scanning and ultrasonography to investigate in what way a known volume of local anesthetic injectate will be distributed in the transverse abdominis plane (TAP) in young healthy male volunteers. The investigators compare the anatomical distribution of the local anesthetic injectate in the TAP when performing an ultrasound-guided classical TAP block and a Dual TAP block. The investigators also want to compare the spread of anesthetized frontal dermatomes when performing an ultrasound-guided classical TAP block and a Dual TAP block.

Eligibility criteria: Inclusion Criteria:

* healthy male
* 18 years old or more
* had no previous abdominal surgery
* no regular medication
* no coagulation disorders
* no claustrophobia

Exclusion Criteria:

* if the volunteer is not able to accept an uncomplicated administration of a classical (single) or dual TAP block

Primary outcomes:
measure: Distribution of local anesthetic evaluated by MR scanning
timeFrame: 30 minutes after administering the TAP blocks
Secondary outcomes:
measure: Spread of anesthetized frontal dermatomes
timeFrame: 30 minutes after administering the TAP blocks
Other outcomes:
Locations:
city: Copenhagen
country: Denmark
facility: Bispebjerg Hospital, Copenhagen University Hospital
state: Capital Region of Denmark
Study officials:
affiliation: Dept. of Anesthesia, Bispebjerg Hospital, Copenhagen University Hospital
name: Jens B Neimann, MD, PhD, MBA
role: PRINCIPAL_INVESTIGATOR
References:
citation: Petersen PL, Mathiesen O, Torup H, Dahl JB. The transversus abdominis plane block: a valuable option for postoperative analgesia? A topical review. Acta Anaesthesiol Scand. 2010 May;54(5):529-35. doi: 10.1111/j.1399-6576.2010.02215.x. Epub 2010 Feb 17.