Clinical trial NCT04966403: Effects of Stretch-shortening Cycle Exercises Postural Control in Down Syndrome
Official title: Distinct Effects of Trampoline-based Stretch-shortening Cycle Exercises on Muscle Strength and Postural Control in Children With Down Syndrome: A Randomized Controlled Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Down Syndrome
Lead sponsor: Qassim University
Sponsor class: OTHER
Collaborators: name: Cairo University
name: Prince Sattam Bin Abdulaziz University
First posted: 2021-07-19
Enrollment: 32
Sex: ALL
Minimum age (years): 7
Maximum age (years): 9
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To investigate the effect of a 3-month, trampoline-based stretch-shortening cycle (SSC) exercises on muscle strength and postural control in children with Down syndrome.

Detailed description: a variety of physical therapy techniques are being used to improve lower limb muscle strength and postural control in children with Down syndrome including, but not limited to, progressive resistance training, hippotherapy, aquatic therapy, and isokinetic strength training. Stretch-shortening (SSC) exercises-also referred to as plyometric exercises, is a traditional form of resistance training that involves three-phase muscle contraction during dynamic movements (like jumping and hopping), where the muscle moves rapidly through the eccentric, isometric, and concentric phases.

Eligibility criteria: Inclusion Criteria:

* age between 7 and 9 years.
* able to follow one step motor commands.
* independent ambulators.
* not suffering from atlantoaxial joint instability as reported from their medical files.

Exclusion Criteria:

* Children with un-corrected cardiac anomalies.
* Children with un-corrected vision or hearing loss.
* Children with un-corrected pulmonary disorders.
* Children with un-corrected neurological signs as epilepsy.
* Children who had a history of musculoskeletal surgery in the lower extremities through the past year.

Primary outcomes:
measure: Grade of Muscle strength by hand-held dynamometer
timeFrame: at baseline
measure: Grade of Muscle strength by hand-held dynamometer
timeFrame: after 12 weeks
Secondary outcomes:
measure: Postural control index by Balance Biodex System
timeFrame: at baseline
measure: Postural control index by Balance Biodex System
timeFrame: after 12 weeks
Other outcomes:
Locations:
city: Al-Kharj
country: Saudi Arabia
facility: King Khalid Hospital
state: Riyadh
Study officials:
affiliation: Cairo University
name: Alshimaa Azab, PhD
role: STUDY_DIRECTOR
References:
citation: Alsakhawi RS, Elshafey MA. Effect of Core Stability Exercises and Treadmill Training on Balance in Children with Down Syndrome: Randomized Controlled Trial. Adv Ther. 2019 Sep;36(9):2364-2373. doi: 10.1007/s12325-019-01024-2. Epub 2019 Jul 12.
citation: Aalizadeh B, Mohammadzadeh H, Khazani A, Dadras A. Effect of a Trampoline Exercise on the Anthropometric Measures and Motor Performance of Adolescent Students. Int J Prev Med. 2016 Jul 13;7:91. doi: 10.4103/2008-7802.186225. eCollection 2016.
citation: Champagne D, Dugas C. Improving gross motor function and postural control with hippotherapy in children with Down syndrome: case reports. Physiother Theory Pract. 2010 Nov;26(8):564-71. doi: 10.3109/09593981003623659. Epub 2010 Jul 31.