Clinical trial NCT06540014: The Difference of Weight Gain Tendencies and Obesity During Pregnancy
Official title: The Difference of Weight Gain Tendencies During Pregnancy According to Pregestational Body Mass Indices of the Mothers in Two Different Ethnic Populations- Does it Make Difference Regarding Neonatal Outcomes?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Obesity, Maternal
Weight Gain, Maternal
Birth Weight
Birth Outcome, Adverse
Keywords: Maternal obesity
neonatal outcome
weight gain in pregnancy
immigrant
Syrian
Turkish
Lead sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital
Sponsor class: OTHER
First posted: 2024-08-06
Enrollment: 323
Sex: FEMALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: In the study, the hospital records of all pregnant women admitted for delivery at the obstetrics ward of the Women's and Children's Diseases additional service building Buca Seyfi Demirsoy Training and Research Hospital were retrospectively reviewed over a 6-month period from September 1, 2022, to February 28, 2023.

Brief summary: Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia, stillbirth, and neonatal death. These risks vary by maternal age, race, and ethnicity, with rising rates among immigrant and minority women. This study investigates overweight and obesity rates in pregnant women, weight gain during pregnancy, and adherence to guidelines and possible neonatal outcomes, comparing Turkish and Syrian immigrant women.

Methods: This retrospective single-center study was conducted at Buca Seyfi Demirsoy Teaching and Research Hospital in Izmir, Turkey, over one year. Data collected included demographic information, pregnancy complications, delivery modes, maternal and neonatal anthropometric measurements, and neonatal morbidity and mortality. The study included Turkish and Syrian women with complete medical records. Statistical analyses were performed using SPSS software, with significance set at p \< 0.05.

Detailed description: Background: Excess weight and obesity are a global pandemic, particularly among women of childbearing age. Pre-pregnancy obesity is linked to adverse maternal and neonatal outcomes, including preterm birth, macrosomia, stillbirth, and neonatal death. These risks vary by maternal age, race, and ethnicity, with rising rates among immigrant and minority women. This study investigates overweight and obesity rates in pregnant women, weight gain during pregnancy, and adherence to guidelines and possible neonatal outcomes, comparing Turkish and Syrian immigrant women.

Methods: This retrospective single-center study was conducted at Buca Seyfi Demirsoy Teaching and Research Hospital in Izmir, Turkey, over one year. Data collected included demographic information, pregnancy complications, delivery modes, maternal and neonatal anthropometric measurements, and neonatal morbidity and mortality. The study included Turkish and Syrian women with complete medical records. Statistical analyses were performed using SPSS software, with significance set at p \< 0.05.

Eligibility criteria: Inclusion Criteria:

* Being admitted to our hospital for delivery or having just given birth
* Being Turkish or Syrian
* Having all detailed information, including mothers' pregestational and immediate pre-delivery body weights, available in medical records

Exclusion Criteria:

* Significant deficiencies in medical records
* Belonging to an ethnic group other than Turkish or Syrian

Primary outcomes:
measure: Maternal weight gain
timeFrame: 1 year period until inclusion
Secondary outcomes:
measure: Obesity and overweight
timeFrame: 6 months
Other outcomes:
measure: Neonatal morbidities
timeFrame: 6 months
measure: Adherence to the weight gain guidelines
timeFrame: 6 months
Locations:
city: Izmir
country: Turkey
facility: Buca Seyfi Demirsoy RTH
Study officials:
affiliation: Izmir Democracy University
name: Suzan Şahin, Assoc.Prof.
role: STUDY_DIRECTOR
References:
citation: Hung TH, Hsieh TT. Pregestational body mass index, gestational weight gain, and risks for adverse pregnancy outcomes among Taiwanese women: A retrospective cohort study. Taiwan J Obstet Gynecol. 2016 Aug;55(4):575-81. doi: 10.1016/j.tjog.2016.06.016.
citation: Zhao R, Xu L, Wu ML, Huang SH, Cao XJ. Maternal pre-pregnancy body mass index, gestational weight gain influence birth weight. Women Birth. 2018 Feb;31(1):e20-e25. doi: 10.1016/j.wombi.2017.06.003. Epub 2017 Jul 14.
citation: Heslehurst N, Ells LJ, Simpson H, Batterham A, Wilkinson J, Summerbell CD. Trends in maternal obesity incidence rates, demographic predictors, and health inequalities in 36,821 women over a 15-year period. BJOG. 2007 Feb;114(2):187-94. doi: 10.1111/j.1471-0528.2006.01180.x.