Clinical trial NCT05037604: Factors Associated With Dermatoporosis
Official title: Factors Associated With Dermatoporosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Senile Purpura
Keywords: dermatoporosis
senile
purpura
Lead sponsor: Universidad Autonoma de San Luis Potosí
Sponsor class: OTHER
First posted: 2021-09-08
Enrollment: 315
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients over 60 years of age who attended the outpatient clinic of the Hospital Central "Dr. Ignacio Morones Prieto "

Brief summary: Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.

The objective was to determine factors associated with this diagnosis in \>60 years old patients of the outpatient clinic in the Hospital Central "Dr. Ignacio Morones Prieto " San Luis Potosí, México.

An observational, cross-sectional, descriptive, and analytical study was performed. Patients \>60 years old were selected. A clinical history, clinical examination, and application of a validated diagnostic self-questionnaire were performed.

Detailed description: Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.The objective was to determine factors associated with this diagnosis in \>60 years old patients of the outpatient clinic in the Hospital Central "Dr. Ignacio Morones Prieto " San Luis Potosí, México.

An observational, cross-sectional, descriptive and analytical study was performed. Through consecutive non-probabilistic sampling, patients \> 60 years old were selected, who underwent a clinical history, clinical examination, and the application of a validated diagnostic self-questionnaire. To determine the association of the factors, a multivariate logistic regression analysis, it will be used the PRIMERv6 software with the PERMANOVA package. A p \<0.05 was considered significant. The normality of the distribution of the continuous variables was evaluated with the Shapiro Wilk test. The Student's t test was performed on variables that met the homogeneity of variance requirements. In the variables that did not meet this criterion, a non-parametric analysis was performed with the Mann U Whitney test. For the analysis of categorical variables, Fisher's exact test or chi-square test was used. Continuous variables were reported by mean (median) \[Q1, Q3\] (min - max) and by standard deviations as their distribution corresponds. Nominal categorical variables were expressed as frequencies

Eligibility criteria: Inclusion Criteria:

* Patients over 60 years

Exclusion Criteria:

* Patients in whom physical examination cannot be performed due to the use of orthopedic devices such as splints, bandages, etc.
* Patients with whom interviewer-patient verbal communication is difficult due to some hearing or neurological deficit.
* Patients with neurological, psychiatric disorders who are unable to provide reliable information. (disorganized, incoherent speech, cognitive deficit)

Primary outcomes:
measure: Factors associated with Dermatoporosis
timeFrame: At time of enrollment
measure: Diagnostic by self assesment tool
timeFrame: At time of enrollment
measure: Physical examination
timeFrame: At time of enrollment
Secondary outcomes:
Other outcomes:
Locations:
city: San Luis Potosi
country: Mexico
facility: Hospital Central "Dr. Ignacio Morones Prieto"
Study officials:
affiliation: Universidad Autonoma de San Luis Potosí
name: Juan Pablo Castanedo-Cazares, PhD
role: PRINCIPAL_INVESTIGATOR
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