Clinical trial NCT01202864: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)
Official title: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Intracerebral Hemorrhage
Keywords: Intracerebral Hemorrhage
ICH
Stroke
Cerebrovascular accident
Lead sponsor: University of Cincinnati
Sponsor class: OTHER
Collaborators: name: Massachusetts General Hospital
name: Columbia University
name: University of Maryland
name: Georgetown University
name: Wake Forest University
name: Emory University
name: University of Miami
name: University of Illinois at Chicago
name: University of Texas, Southwestern Medical Center at Dallas
name: The University of Texas Health Science Center, Houston
name: The University of Texas Health Science Center at San Antonio
name: University of New Mexico
name: University of Arizona
name: University of Southern California
name: St. Luke's-Roosevelt Hospital Center
name: University of California, San Francisco
name: Duke University
name: University of Virginia
name: National Institute of Neurological Disorders and Stroke (NINDS)
First posted: 2010-09-16
Enrollment: 6000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Our purpose is to enroll 1000 cases of ICH among whites, 1000 cases of ICH among blacks, and 1000 cases of ICH among Hispanics.

3000 controls matched to cases by race/ethnicity, age (+/- 5 years), gender, and geographic location.

Brief summary: The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH), among Caucasians, African Americans, and Hispanics.


Eligibility criteria: Inclusion Criteria:

All cases must meet the following eligibility criteria:

1. Age 18 years or greater, fulfillment of the criteria for intracerebral hemorrhage
2. Resident for at least 6 months within 50 miles of the recruiting center
3. No evidence of trauma, vascular malformation or aneurysm, or brain tumor as a cause of the hemorrhage
4. Ability of the patient or legal representative to provide informed consent

Exclusion Criteria:

Exclusion Criteria:

1. Malignancies leading to coagulopathy
2. Hemorrhagic transformation of ischemic infarct
3. Hemorrhage secondary to dural venous sinus thrombosis

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Tucson
country: United States
facility: University of Arizona
state: Arizona
city: Los Angeles
country: United States
facility: University of Southern California
state: California
city: Washington, D.C.
country: United States
facility: Georgetown University
state: District of Columbia
city: Miami
country: United States
facility: University of Miami - Biorepository
state: Florida
city: Miami
country: United States
facility: University of Miami
state: Florida
city: Atlanta
country: United States
facility: Emory University
state: Georgia
city: Chicago
country: United States
facility: University of Illinois
state: Illinois
city: Baltimore
country: United States
facility: University of Maryland
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
city: Albuquerque
country: United States
facility: University of New Mexico
state: New Mexico
city: New York
country: United States
facility: Columbia University
state: New York
city: Winston-Salem
country: United States
facility: Wake Forest University
state: North Carolina
city: Dallas
country: United States
facility: University of Texas Southwestern Medical Center at Dallas
state: Texas
city: Houston
country: United States
facility: University of Texas Medical School at Houston
state: Texas
city: San Antonio
country: United States
facility: University of Texas Health Science Center at San Antonio
state: Texas
Study officials:
affiliation: University of Cincinnati
name: Daniel Woo, MD, MS
role: PRINCIPAL_INVESTIGATOR
affiliation: University of Cincinnati
name: Matthew Flaherty, MD
role: PRINCIPAL_INVESTIGATOR
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