Clinical trial NCT03785002: Comparison of the Increment of Neuromuscular Parameters in Vegetarians and Non-vegetarians
Official title: Comparison of Strength and Muscle Thickness of Recreational Sports Individuals With Vegetarian or Non-vegetarian Food Standards Adequate in Proteins
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Strength Training
Dietary Proteins
Muscle Strength
Hypertrophy
Lead sponsor: Hospital de Clinicas de Porto Alegre
Sponsor class: OTHER
First posted: 2018-12-24
Enrollment: 64
Sex: ALL
Minimum age (years): 19
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: A strength training session promotes increased muscle sensitivity to protein synthesis, which lasts for 24 hours after its closure. Recent studies have shown that the subsequent intake to the training session of approximately 20g or 0.24g / kg of high-quality protein in the same meal induces a plateau in this synthesis. Thus, this study aims to compare the muscular strength between vegetarian and omnivorous athletes with adequate protein intake to reach this plateau. It will recruit 64 university sportsmen who have maintained vegetarian or omnivorous diet for at least 6 months, totalizing 32 individuals per group. After signing the Term of Consent, participants will be submitted to anthropometric and body composition assessment (via DEXA), neuromuscular tests \[(ie, muscle strength - 1RM, peak torque of knee extensors (JE), muscle thickness of JE and cohort analysis (ANCOVA) will be used in order to compare the results of the study, and to compare the results of the covariance analysis (ANCOVA). the levels of the neuromuscular parameters between the groups, considering the initial values of the force and the initial muscular thickness as covariables, the other parameters will be presented in the form of mean and standard deviation or median, the differences will be considered significant for values of p \<0, 05. Expected to find no differences in strength and muscle thickness between vegetarians and omnivores after adequate protein intake.


Eligibility criteria: Inclusion Criteria:

* Be over the age of 19 and under 60;
* Have BMI \<30 kg / m²;
* Be vegetarian or omnivorous for at least 6 months;
* Have not exercised regularly for at least 6 months.
* Be available to practice bodybuilding at School of Physical Education, Physiotherapy and Dance, 2x / week, for 3 months, free (times to combine).

Exclusion Criteria

* Be vegan, vegetarian lacto or vegetarian egg
* Be a carrier of chronic diseases;
* Present physical limitations or musculoskeletal problems, which contraindicate the performance of strength exercises;
* Failure to adhere to the proposed dietary modifications, relating to the adequacy of the portion of protein per meal, due to financial unfeasibility (low income condition);
* Use of protein or amino acid, caffeine or other thermogenic food supplements.

Primary outcomes:
measure: Muscle Thickness (mm)
timeFrame: At the14th week of study participation.
Secondary outcomes:
measure: Maximal strength (kg)
timeFrame: At the 14th week of study participation.
measure: Isometric peak torque (PTiso) (N.m)
timeFrame: At the 14th week of study participation.
measure: Body fat free mass (g)
timeFrame: At the 14th week of study participation
measure: Body fat mass (g)
timeFrame: At the14th week of study participation.
measure: Protein intake (g)
timeFrame: At the 14th week of study participation.
Other outcomes:
Locations:
city: Porto Alegre
country: Brazil
facility: Gabriela Luccciana Martini
state: Rio Grande Do Sul
Study officials:
affiliation: Hospital de Clínicas de Porto Alegre
name: Carolina G de Souza, PHD
role: PRINCIPAL_INVESTIGATOR
References: