Clinical trial NCT03893981: Strengthening Exercises Versus Proprioception and Balance Exercises in the Treatment of Knee Osteoarthritis
Official title: Comparison of the Effect of Strengthening Exercises Versus Proprioception and Balance Exercises in the Treatment of Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteo Arthritis Knee
Pain
Keywords: Rehabilitation
Pain
Functionality
Proprioception
Lead sponsor: Istanbul University
Sponsor class: OTHER
First posted: 2019-03-28
Enrollment: 48
Sex: ALL
Minimum age (years): 45
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of the study is to investigate and compare the effect of balance and proprioception exercises with strengthening exercises on muscle strength, pain, proprioception, function and quality of life in knee osteoarthritis patients.

Detailed description: Damage or loss of mechanoreceptors in osteoarthritis patients affects balance and proprioception. There are studies showing that proprioceptive deficit is associated with the onset and progression of knee osteoarthritis leading to pain and disability. Because the proprioception provides a sense of power generation and allows the power output to be better regulated. When the literature is examined, studies investigating the effects of proprioception and balance exercises on muscle strength, function and pain are limited.

In our study patients will be randomly divided into two groups: Group I (Proprioception and Balance) and Group II (muscle strengthening exercises). While Group I will be applied Proprioception and Balance training exercises, Group II will be applied closed and open kinetic strengthening exercises. Two group will perform exercise 3 times a week during 8 weeks.

Eligibility criteria: Inclusion Criteria:

* Patients who have a diagnosis of knee Osteoarthritis according to the American Society of Rheumatology (ACR) criteria,
* Between 45 to 75 years of age
* Can read and write in Turkish language

Exclusion Criteria:

* Active synovitis
* Taking any physical therapy section in the last 6 months
* Have a neurological problems that affect walking
* Have an arthritis problem in the ankle and hip joint
* Have a history of lower extremity surgery
* Intraarticular steroid injection in the last 6 months
* Use psychoactive drug
* Have a severe defect of vision and hearing, speech disorders
* Vestibular dysfunction

Primary outcomes:
measure: Western Ontario and McMaster Universities Arthritis Index (WOMAC)
timeFrame: WOMAC will be filled first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program . After treatment "change" will be assessed
Secondary outcomes:
measure: Visual Analogue Scale (VAS)
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Pressure Algometer
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Hand-Held Dynamometer
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Isokinetic Dynamometer for measuring position sense
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Short Form-36
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Global Rating of Change Scale
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Aggregated Locomotor Function (ALF) Score
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Digital Goniometer
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Timed Up and Go (TUG) Test
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
measure: Tandem and Stand on One Leg
timeFrame: Evaluation will perform first time at baseline and second time after 4 weeks and third time after 8 weeks rehabilitation program.
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul University-Cerrahpasa, Faculty Of Health Sciences
state: Bakirkoy
Study officials:
affiliation: Istanbul University
name: Gamze Kuş, MsC
role: PRINCIPAL_INVESTIGATOR
References: