Clinical trial NCT05371821: Cardiac Assessment in Obese and Overweight Children
Official title: Cardiac Assessment of Obese and Overweight Children Attending Asyut University Children Hospital
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Obesity, Childhood
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2022-05-12
Enrollment: 50
Sex: ALL
Minimum age (years): 2
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Obese and overweight children from 2 years till age of 18 years .

Brief summary: Is to assess cardiac functions of overweight and obese children attending assiut University children hospital in one year duration .

Detailed description: The prevalence of overweight and obesity in children is increasing worldwide at an alarming rate in both developing and developed countries .the relation between obesity and cardiac structure and function in children is less well documented and conflicting results have been reported .In addition, obesity is associated with a heterogeneity of metabolic abnormalities , (e.g., dyslipidemia , insulin resistance hyperglycaemia and hypertension , that may provide a plausible biologic link between obesity and the increased risk of cardiovascular morbidity and mortality .The clustering of these risk factors for cardiovascular disease is referred to as the "metabolic syndrome." Although the concept and definition of the metabolic syndrome are controversial at the moment, there is no doubt that a cluster of cardiovascular risk factors is present in obese children and adolescents and that their presence increases with worsening obesity .children are likely to be the ideal candidates for providing insight into the myocardial changes related to obesity because they are suggested to be free of other cardiovascular risk factors indifferent echocardiographic studies .

Eligibility criteria: Inclusion Criteria:

1. - Age: children at 2-18 years .
2. - Overweight children whose body mass index at or above the 85th percentile and below the 95th percentile for the same age and sex
3. - Obese children whose body mass index at or above the 95th percentile for the same age and sex.

Exclusion Criteria:

1- Obese children below two years 2 - Cases with syndromic obesity, diabetes

* thyroid and parathyroid and those with congenital heart diseases

Primary outcomes:
measure: Cardiac assessment of obese and overweight children
timeFrame: Baseline
measure: Assessment of body mass index
timeFrame: baseline
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
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