Clinical trial NCT03376308: Evaluation of the Effect of Venous Diameter Measurement by Ultrasonography on Pain and Withdrawal Response
Official title: Evaluation of the Effect of Venous Diameter Measurement by Ultrasonography on Pain and Withdrawal Response
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pain
Withdrawal
Keywords: rocuronium
propofol
pain
withdrawal
venous diameter
Lead sponsor: Aydin Adnan Menderes University
Sponsor class: OTHER
First posted: 2017-12-18
Enrollment: 145
Sex: ALL
Minimum age (years): 17
Maximum age (years): 70
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The study was conducted on 145 patients aged 17- 70 years of ASA (American Society of Anesthesiologists) physical status I- II who were to undergo various elective operations. None of the patients was premedicated before the operation. Venous diameter measurements were performed in preoperative room via USG.The patients were monitored with three derivation electrocardiogram, non- invasive arterial pressure, and pulse oximeter.

Brief summary: During general anesthesia, intravenous (IV) medications can disrupt the patient's comfort by causing a pain sensation or a withdrawal response in the heart. Propofol and rocuronium are among the most common causes of this condition.

In recent years, the use of ultrasonography (USG) in anesthesia has become widespread with the rapid advancement of technology. The use of the patient's head is a non invasive method.

This study is aimed to evaluate whether the size of the venous diameter assessed by ultrasonography in our study is an effect on pain and withdrawal response after drug injections.

Detailed description: The study was conducted in patients who underwent surgical procedures under general anesthesia by obtaining consent from the Adnan Menderes University Medical Faculty Ethics Board and written consent from the patients and then being admitted to the ASA I-II age group 18-70 years of age.

Patients with peripheric vascular disease, vasculitis, rheumatologic disease, non-cooperative, under the age of 18 and over 70, ASA III and above, allergic to general anesthetic agents and refusing to participate in the study were excluded from the study.

Eligibility criteria: Inclusion Criteria:

18- 70 years of ASA (American society of anesthesiology) physical status I- II who were to undergo various elective operations

Exclusion Criteria:

Rheumatologic disease Peripheric vascular disease Vasculitis Patients with chronic pain syndrome, Patients with neurologic deficits, Patients with thrombophlebitis, Patients with difficult venous access, Patients with allergy

Primary outcomes:
measure: The injection pain due to propofol
timeFrame: 6 month
Secondary outcomes:
measure: The withdrawal movement due to rocuronium
timeFrame: 6 month
Other outcomes:
Locations:
city: Aydın
country: Turkey
facility: Adnan Menderes University Training and Research Hospital
Study officials:
affiliation: Aydin Adnan Menderes University
name: Sinan Yılmaz
role: PRINCIPAL_INVESTIGATOR
References: