Clinical trial NCT05904821: Relationship Between BMI, Physical Fitness and Motor Skills in Children With Down's Syndrome
Official title: Relationship Between BMI, Physical Fitness and Motor Skills in Children With Down's Syndrome
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Down Syndrome
Keywords: BMI
Down Syndrome
Motor Skills
Physical Fitness
Test of Gross Motor Development (TGMD-2)
SAMU Disability Fitness Battery (SAMU-DISFIT)
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-06-15
Enrollment: 169
Sex: ALL
Minimum age (years): 4
Maximum age (years): 15
Standard ages: CHILD
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: DownsSyndrome

Brief summary: Down syndrome is a congenital condition which includes physical mental, and functional abnormalities. It arises from defect involving chromosome 21, usually an extra copy (trisomy 21). Purpose of this study will determine the relationship between BMI, physical fitness and motor skills in youth with down syndrome

Detailed description: This will be a cross-sectional study. The sample size is 169. The inclusion criteria will be Diagnosed with trisomy 21, Aged 6-11 years, Abel to follow a minimum of two-step instructions, The minimum motor ability of participants with DS is independent locomotion where as the exclusion criteria will be medical condition that is contraindicated to moderate to vigorous physical activity such as cardiovascular problems, orthopedic instability, including those associated with DS (e.g., Atlanto-axial instability), behavioral issues that hindered instruction. The BMI will be assessed using a person's height and weight. The formula is BMI = kg/m 2 where kg is a person's weight in kilograms and m 2 is their height in meters squared. Physical Fitness by using SAMU Disability Fitness Battery (SAMU-DISFIT). the Timed Up and Go test (TUG), the Deep Trunk Flexibility test (DTF), the Hand Grip test (HG), the Timed Stand Test (TST), the 30-s Sit-Up (SUP), the 6-Min Walk Test (6MWT) and Motor Skills using Test of Gross Motor Development (TUG-2) Data will be analyzed using SPSS 22.0. Frequency tables and bar charts will be used for descriptive statistics Chi-Square will be used to find the Association

Eligibility criteria: Inclusion Criteria:

* Diagnosed with trisomy 21.
* Aged 5-15 years.
* Abel to follow a minimum of two-step instructions.
* The minimum motor ability of participants with DS is independent locomotion.

Exclusion Criteria:

* Medical condition that is contraindicated to moderate to vigorous physical activity such as cardiovascular problems.
* Orthopedic instability, including those associated with DS (e.g., Atlanto-axial instability).
* Behavioral issues that hindered instruction

Primary outcomes:
measure: Time up and go (TUG)
timeFrame: 2 months
measure: The Deep Trunk Flexibility test (DTF)
timeFrame: 2 months
measure: The Hand Grip test (HG).
timeFrame: 2 months
measure: Timed Stand Test (TST).
timeFrame: 2 months
measure: The 30-s Sit-Up (SUP).
timeFrame: 2 months
measure: The 6-Min Walk Test (6MWT)
timeFrame: 2 months
measure: BMI (BMI = kg/m2)
timeFrame: 2 months
measure: Waist Circumference
timeFrame: 2 months
measure: ROM
timeFrame: 2 months
measure: Run
timeFrame: 2 months
measure: Gallop
timeFrame: 2 months
measure: Hop
timeFrame: 2 months
measure: Leap
timeFrame: 2 months
measure: Horizontal Jump
timeFrame: 2 months
measure: Skip
timeFrame: 2 months
measure: Slide
timeFrame: 2 months
measure: Two Hand strike
timeFrame: 2 months
measure: Stationary Bounce
timeFrame: 2 months
measure: Catch
timeFrame: 2 months
measure: kick
timeFrame: 2 months
measure: Overhead Throw
timeFrame: 2 months
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Riphah International University
state: Punjab
Study officials:
affiliation: Riphah International University
name: Mahnoor Bukhari, MS
role: PRINCIPAL_INVESTIGATOR
References: