Clinical trial NCT06925802: Osteopathic Visceral Manipulation on Functional Constipation in Obese Adults
Official title: Osteopathic Visceral Manipulation on Functional Constipation in Obese Adults: Randomized Controlled Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Constipation - Functional
Lead sponsor: MTI University
Sponsor class: OTHER
First posted: 2025-04-13
Enrollment: 110
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: RCT
Primary purpose: TREATMENT

Brief summary: Functional constipation in obese adults is a prevalent gastrointestinal issue characterized by infrequent bowel movements, difficulty during defecation, or a sensation of incomplete evacuation. Obesity is a significant risk factor for functional constipation due to several physiological and lifestyle-related factors. Excess body weight, particularly in the abdominal region, may exert pressure on the colon, leading to disrupted bowel function. Additionally, dietary habits common among obese individuals, such as low fiber intake and inadequate hydration, can worsen constipation. Sedentary lifestyles further contribute to reduced gastrointestinal motility. Addressing functional constipation in obese adults requires a multifaceted approach, including dietary modifications to increase fiber and fluid intake, regular physical activity, and, in some cases, medical interventions to alleviate symptoms and improve quality of life.

Detailed description: Visceral manipulation is a gentle manual therapy that focuses on the internal organs, particularly those within the gastrointestinal tract, to enhance their function and alleviate symptoms associated with various disorders. Practitioners of visceral manipulation use their hands to apply specific, subtle forces to the affected areas, aiming to improve the mobility and motility of the organs. This technique is based on the premise that the body's organs are interconnected by fascia and ligaments, and any restriction or imbalance in these connections can lead to dysfunction and disease. By restoring the natural movement of these organs, visceral manipulation is believed to improve blood circulation, enhance digestive function, and reduce pain and discomfort associated with gastrointestinal disorders.

Eligibility criteria: Inclusion Criteria:

* patients diagnosed with functional constipation according to Rome IV criteria
* Body mass index (BMI) ≥ 30 kg/m²
* Ability to provide informed consent

Exclusion Criteria:

* patients with organic gastrointestinal diseases, Pregnancy or lactation
* Participation in another clinical trial within the last 30 days, Endocrine and metabolic disorders (eg, hypothyroidism, hypercalcemia, diabetes mellitus, diabetes insipidus)
* Neurologic and psychiatric disorders (spina bifida, cerebral palsy, anorexia nervosa, known autism spectrum disorders)
* Secondary constipation to drug consumption, History of abdominal surgery

Primary outcomes:
measure: Stool consistency
timeFrame: at baseline and at three weeks
measure: Defecation Pain
timeFrame: at baseline and at three weeks
Secondary outcomes:
measure: Defecation frequency
timeFrame: at baseline and at three weeks
measure: Dose of oral laxative
timeFrame: at baseline and at three weeks
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: faculty of physical therapy ,Cairo University
Study officials:
References: