Clinical trial NCT06521203: Periapical Lesions and Immediate Implants
Official title: Immediate Implant Placement in Sites With Chronic Periapical Lesions
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Dental Implant Failure Nos
Periapical Granuloma
Osseointegration Failure of Dental Implant
Keywords: Dental implant
Immediate dental implant
Osseointegrated implants
Osseointegration
Periapical granuloma
Tooth extraction
Lead sponsor: Akdeniz University
Sponsor class: OTHER
First posted: 2024-07-25
Enrollment: 25
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The present study included patients, who underwent immediate implant placement following extraction of a tooth with periapical pathology.

Brief summary: The aim of this case-control study is to evaluate the success and survival rates of dental implants immediately placed into extraction sites in the presence of periapical pathology.

The main questions it aims to answer are:

What were the survival and success rates of implants immediately placed into extraction sockets of teeth with chronic periodical lesions.

A retrospective analysis was performed based on the evaluation of certain clinical and radiographic parameters 12 months after prosthetic function of these implants.

Detailed description: In 25 patients (13 men, 12 women), certain clinical and radiological parameters were retrospectively evaluated with particular interest in survival and success rates of the implants (total of 30 implants, 21 in the maxilla, 9 in the mandible) placed immediately to extraction sites of teeth with chronic periapical lesions. These parameters included mobility and the presence or absence of chronic pain, probing depth, gingival index, radiographic measurements of crestal bone loss on mesial and distal aspects of the implants.

Eligibility criteria: Inclusion Criteria:

* To have 1 or more teeth with a chronic periapical lesion that requiring extraction.
* The chronic periapical lesion should be determined as an asymptomatic periapical radiolucency with a diameter ranging between 4 and 8 mm.
* The patients undergoing tooth extraction must have been treated with an immediate implant placement procedure.
* At the time of extraction and implant placement, the neighboring teeth must have had healthy periodontal and periapical status.

Exclusion Criteria:

* Age younger than 18 years
* Any systemic disease or medication that might compromise osseointegration, bone or soft tissue healing
* Smoking
* Purulent exudate during the extraction
* Severe deficiency of soft and/or hard tissue in implant region
* Pregnancy
* Lactation
* History of chemotherapy or radiotherapy
* Severe parafunctional habits

Primary outcomes:
measure: Survival of the implants
timeFrame: Immediately after the implant placement and after 12 months of prosthesis function.
measure: Success of the implants
timeFrame: Immediately after the implant placement and after 12 months of prosthesis function.
Secondary outcomes:
Other outcomes:
Locations:
city: Antalya
country: Turkey
facility: Akdeniz University
Study officials:
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