Clinical trial NCT06762184: Scores in Critically Ill Patients After Craniotomy
Official title: Comparison of the Predictive Value of APACHE II, SOFA, SAPS II, GCS and GCS-P Scores for In-hospital Mortality in Critically Ill Patients After Craniotomy
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Post-craniotomy
Critical Illness
Mortality
Severity of Illness Scores
Keywords: critical ill
post-craniotomy
APACHE II
SOFA
SAPS II
GCS
GCS-P
mortality
Lead sponsor: Beijing Tiantan Hospital
Sponsor class: OTHER
First posted: 2025-01-07
Enrollment: 1600
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients admitted to the ICU wards between 2017 and 2020 would be screened, and those who underwent craniotomy and had an ICU stay of more than 24 hours were eligible for inclusion. For patients with multiple ICU admissions during a single hospitalization, only the first admission was included. Pregnant or lactating women, as well as patients enrolled in other clinical studies, would be excluded.

Brief summary: This study planned to review patients admitted to three ICU wards at Beijing Tiantan Hospital between 2017 and 2020. It focused on adult patients who had undergone craniotomy and stayed in the ICU for more than 24 hours. Researchers intended to collect patient information, surgery details, complications, and outcomes from medical records. They also planned to gather routine scoring data used at the hospital and double-check its accuracy. Patients would be divided into two groups based on whether they survived or not, and the ability of different scoring systems to predict outcomes would be analyzed. Additionally, the study aimed to group patients by the type of surgery and assess how well the scoring systems predicted outcomes for each group.

Detailed description: This study would screen patients admitted to three ICU wards at Beijing Tiantan Hospital from 2017 to 2020. Adult postoperative craniotomy patients with an ICU stay of more than 24 hours would be included. Baseline information, surgery-related data, complications, and outcomes would be retrospectively collected. Routine scoring assessments conducted at our center would be gathered, and researchers would verify the accuracy of the scoring data. Based on patient outcomes, the cohort would be divided into a mortality group and a survival group. The predictive value of different scoring systems for patient outcomes would be evaluated. Additionally, patients would be grouped according to surgical indications, and the predictive value of the scoring systems for outcomes in patients with different surgical indications would be assessed.

Eligibility criteria: Inclusion Criteria:

* Patients admitted to the ICU wards between 2017 and 2020
* Patients underwent craniotomy
* Patientshad an ICU stay of more than 24 hours

Exclusion Criteria:

* Pregnant or lactating women
* Patients enrolled in other clinical studies

Primary outcomes:
measure: predictive value of different scoring systems
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: Chile
facility: Beijing Tiantan Hospital, Capital Medical University
Study officials:
References: