Clinical trial NCT06793384: Virtual Reality in Cognitive Stimulation Therapy for Visually Impaired Older Individuals with Dementia
Official title: Applying Cognitive Stimulation Therapy (CST) and Virtual Reality-based CST on People with Concurrent Visual Impairment and Dementia: a Feasibility Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dementia Patients
Lead sponsor: The Hong Kong Polytechnic University
Sponsor class: OTHER
Collaborators: name: The University of Hong Kong
name: The Hong Kong Society for the Blind
name: Tung Wah College
First posted: 2025-01-27
Enrollment: 31
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Both visual impairment and dementia are prevalent in the elderly population. Cognitive stimulation therapy (CST) is an evidence-based intervention for people with mild-to-moderate dementia. Virtual reality (VR) has been used in cognitive rehabilitation. However, the efficacy of CST and the feasibility of incorporating VR into therapy targeting people with dementia and visual impairment (PwDVI) have rarely been explored. The current pilot study addressed two issues: 1) To study the efficacy of conventional CST on PwDVI in different cognitive domains and 2) To explore the feasibility and efficacy of VR-CST on PwDVI in various cognitive domains.


Eligibility criteria: Inclusion Criteria:

1. Cantonese speakers;
2. suspected or having a medical diagnosis of dementia, with the Montreal Cognitive Assessment 5-minute protocol (MoCA-5) score ranging from 2 to 17, which is equal to the Cantonese Mini Mental State Examination (MMSE) score ranging from 10 to 24 by using the conversion table from Wong et al,
3. a diagnosis of mild to moderate visual impairment determined by an optometrist,
4. no other disability including physical illness, learning disability and severe hearing impairment that may affect participation in group activity,
5. not currently on psychiatric medication/cognitive intervention, (6) no history of other neurological diseases, and

(7) did not receive any prior CST.

Exclusion Criteria:

1. currently on psychiatric medication/cognitive intervention, (6) no history of other neurological diseases,
2. currently on psychiatric medication/cognitive intervention, (6) no history of other neurological diseases,
3. prior exposure to CST

Primary outcomes:
measure: The Hong Kong version of the Montreal Cognitive Assessment for the Visually Impaired (HKMoCA-VI)
timeFrame: The assessment was administered three times 15 days before and after treatment.
Secondary outcomes:
measure: Holden Communication Scale
timeFrame: It was administered once one week before and after the intervention.
measure: Cantonese version of the Amsterdam-Nijmegan Everyday Language Test (CANELT)
timeFrame: Three times 15 days before and after treatment
measure: Procedural description of making a ham-and-egg sandwich
timeFrame: The assessment was administered three times 15 days before and after treatment.
measure: Synonym judgement
timeFrame: The assessment was administered three times 15 days before and after treatment.
Other outcomes:
Locations:
city: Hong Kong
country: Hong Kong
facility: The Hong Kong Society for the Blind
Study officials:
References: