Clinical trial NCT02280668: Investigating Muscle Repair in Response to Icing Therapy Post Eccentric Muscle Damage Exercise
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Muscle Damage
Keywords: muscle
muscle repair
tissue repair
eccentric exercise
force loss
icing
cold therapy
DOMS
soreness
recovery
Lead sponsor: Wilfrid Laurier University
Sponsor class: OTHER
First posted: 2014-10-31
Enrollment: 45
Sex: ALL
Minimum age (years): 18
Maximum age (years): 24
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of our research is to investigate the effects of applying cold therapy, or "icing," to injured muscles in terms of strength recovery and muscle soreness amelioration following unaccustomed exercise.

Detailed description: The objective is to determine whether or not injured muscles that are subject to icing after eccentrically damaging exercise recover their strength quicker and/or have less muscle soreness than those that do not receive any icing treatment after damaging exercise and if any differences in effectiveness between two icing protocols exist. Baseline measures of peak torque of the dominant arm's elbow flexor muscles will be measured by concentric and isometric contractions prior to participants undergoing eccentric muscle damaging exercise. Participants will be randomly assigned into 3 different experimental groups of approximately 15 participants each. The first group will begin "Icing Protocol 1" at time 0 (or as close to). The second group will begin "Icing Protocol 2" six hours after their initial eccentric muscle damaging exercise. The remaining group will not receive any icing treatment; they are the control group. Participants will be brought back into the lab at specific post-exercise times (0h, 24h, 48h, 96h, and 7 days) to complete peak torque measures as they did with baseline measures prior to eccentric muscle damage. Measures of delayed onset muscle soreness (DOMS) will also be taken at baseline and during scheduled follow up times for participants.

Eligibility criteria: Inclusion Criteria:

* Healthy students attending Wilfrid Laurier University with no previous history of upper body muscle damage and live in close proximity to the University so they can attend all lab sessions. Ideally they have not performed any upper body resistance training within the last 4 months.

Exclusion Criteria:

* Previous history of muscle, joint, or ligament injuries in the surrounding area of their dominant are elbow flexor region.

Primary outcomes:
measure: Peak torque strength measures determined using the CYBEX-NORM Testing and Rehabilitation System
timeFrame: Within 7 days post eccentric muscle damage
measure: Delayed onset muscle soreness determined using the VAS scale of perceived muscle soreness
timeFrame: Within 7 days post eccentric muscle damage
Secondary outcomes:
Other outcomes:
Locations:
city: Waterloo
country: Canada
facility: Wilfrid Laurier University
state: Ontario
Study officials:
affiliation: Wilfrid Laurier University, Faculty of Health Sciences
name: Peter Tiidus, PhD
role: STUDY_DIRECTOR
References: