Clinical trial NCT06943079: PNF and BFR Affect on Pain, ROM & Functional Outcome in Post-op ACL
Official title: Effects of Hold-relax Technique With or Without Blood Flow Restriction on Pain, Range of Motion and Functional Disability in Patients With Post Operative ACL Rehabilitation.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Sports Physical Therapy
Keywords: ACL reconstruction
Hamstring graft
Hold relax technique
Blood flow restriction
Knee joint
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2025-04-24
Enrollment: 48
Sex: ALL
Minimum age (years): 25
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: 2 groups; A for the application of HRT B includes HRT and BFR Their effects will be noted on 0 week, 3rd week and 6th week to conclude its result.
Primary purpose: TREATMENT

Brief summary: A randomized controlled trial investigated the effects of Hold Relax Technique (HRT) with and without Blood Flow Restriction (BFR) on pain, range of motion (ROM), and functional disability in patients with post-operative ACL rehabilitation. This study includes all types of genders with age limit is 25-45 years. But the aim is to infer the answers to the following questions; Does HRT has better effects than HRT with BFR? How much effect should be noted ? The research will show that if both HRT and HRT with BFR groups had significant pain reduction, the HRT with BFR group demonstrated greater ROM improvement and significant enhancement in functional ability compared to the HRT and control groups.

Detailed description: A randomized clinical trial will be conducted under Riphah International University guidelines and nonprobability convenient sampling will be used to collect data from the 48 participants from the Ghurki trust and teaching hospital setting. Participants will go through ACL reconstruction specifically the usage of a hamstring graft. The participants were allocated into two groups by using randomization through computer-generated software A and B. In A group only HRT will be applied to check the effects on pain, ROM, and functional disability. In the B group HRT with BFR will be utilized to note the effects on pain, ROM, and functional disability.

Eligibility criteria: Inclusion Criteria:

* Age group 25-45 years.
* Both gender male and female.
* Patient underwent arthroscopic ACL repair procedure.
* Patients in 6 weeks of rehabilitation phase.
* Grafts of hamstring muscle were used in repair.
* Max range achieved after post-op day 1.
* Low- moderate pain intensity.

Exclusion Criteria:

* Any form of bone carcinoma.
* Any Post-OP active infectionous Patients.
* Any circulatory effects.
* DVT and pulmonary embolism.
* Loose Implant placement.
* Non co-operative Patient.
* Hyperasthetic Patient.
* Polytraumatic Post-OP Patient.

Primary outcomes:
measure: 1- BFR Cuff
timeFrame: 6 weeks
measure: 2- UNIVERSAL GONIOMETER
timeFrame: 6 weeks
measure: 3- NUMERIC PAIN RATING SCALE (NPRS)
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Ghurki Trust and Teaching Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Humera Mubashar Senior Lecturer, MS-OMPT
role: PRINCIPAL_INVESTIGATOR
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