Clinical trial NCT04303923: Reference Diameter and Characteristics of Distal Radial Artery by Ultrasonographic Assessement in Korean Patients
Official title: Reference Diameter and Characteristics of Distal Radial Artery by Ultrasonographic Assessement in Korean Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Radial Artery
Keywords: anatomical snuffbox
distal radial artery
radial artery
Lead sponsor: Wonju Severance Christian Hospital
Sponsor class: OTHER
First posted: 2020-03-11
Enrollment: 1162
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients planned to perform transthoracic echocardiography with arterial ultrasonography were consecutively enrolled in a single center.

Brief summary: Radial access is recommended as the standard approach for coronary angiography (CAG) and percutaneous coronary intervention (PCI) based on the evidence in which RA reduced mortality and bleeding events compared with femoral access. Recently, the use of distal radial artery (DRA) is rapidly increasing in accordance with the publication of several studies that have shown easy hemostasis, reduced bleeding complications and low arterial occlusion rate via distal radial approach. However, the diameter of DRA is relatively smaller than radial artery (RA) which can limit the widespread use of this access route. Regarding the size discrepancy, there is a lack of evidence to guide which patients are acceptable or not for CAG and PCI. Therefore, the main purpose of this study was to provide the reference diameter of DRA using ultrasonography in Korean patients. The clinical predictors for small DRA also were evaluated.

Detailed description: Radial access is recommended as the standard approach for coronary angiography (CAG) and percutaneous coronary intervention (PCI) based on the evidence in which RA reduced mortality and bleeding events compared with femoral access. Recently, the use of distal radial artery (DRA) is rapidly increasing in accordance with the publication of several studies that have shown easy hemostasis, reduced bleeding complications and low arterial occlusion rate via distal radial approach. However, the diameter of DRA is relatively smaller than radial artery (RA) which can limit the widespread use of this access route. Regarding the size discrepancy, there is a lack of evidence to guide which patients are acceptable or not for CAG and PCI. Therefore, the main purpose of this study was to provide the reference diameter of DRA using ultrasonography in Korean patients. The clinical predictors for small DRA also were evaluated.

Assessment of arterial diameter by ultasonography Patients were lying on the bed with relaxation in an quiet room. The outer diameters of both DRA and RA were assessed by a perpendicular angle using a linear ultrasound probe (3-4-10.8 MHz) and the average values were recorded. The diameter of RA was measured from 2-3 cm above wrist crease. Anatomical landmark for the measurement of DRA was the bony surface area just distal space from extensor pollicis longus tendon in which the DRA was best palpable then runs down between the first metacarpal and second metacarpal bone (just out of anatomical snuffbox area)

Eligibility criteria: Inclusion Criteria:

* Patients planned to perform transthoracic echocardiography with arterial ultrasonography

Exclusion Criteria:

* Age under 20-year
* Poor image quality
* repeated measurement

Primary outcomes:
measure: The diameter of distal radial artery
timeFrame: Through ultrasonographic evaluation (within 1 hour)
Secondary outcomes:
measure: The diameter of radial artery
timeFrame: Through ultrasonographic evaluation (within 1 hour)
measure: Arterial diameter index
timeFrame: Through ultrasonographic evaluation (within 1 hour)
measure: Proportion of small distal radial artery
timeFrame: Through ultrasonographic evaluation (within 1 hour)
measure: Predictor for small distal radial artery
timeFrame: Through ultrasonographic evaluation (within 1 hour)
Other outcomes:
Locations:
city: Wonju
country: Korea, Republic of
facility: Wonju Severance Christian Hospital
state: Gangwon-do
Study officials:
affiliation: Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital
name: Jun-Won Lee, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: