Clinical trial NCT05311202: The Effect of Acute Resistance Exercise on Inhibitory Control
Official title: The Effect of Training Volume and Intensity of Acute Resistance Exercise on Inhibitory Control: An Event-Related Potential Study
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Exercise
Cognitive Function
Keywords: Acute resistance exercise
Inhibitory control
Training volume
Intensity
Event-related potential
Lead sponsor: National Taiwan Normal University
Sponsor class: OTHER
First posted: 2022-04-05
Enrollment: 175
Sex: ALL
Minimum age (years): 20
Maximum age (years): 26
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The current study is a five-arm, single bout program aiming to assess the effects of training volume and intensity of acute resistance exercise on inhibitory control on neurocognitive function with respect to event-related potential in adults aged 20 - 26 years.

Detailed description: The current study is expected that 175 healthy adults will be recruited and randomly assigned to control group, low volume-moderate intensity, moderate volume-moderate intensity, high volume-moderate intensity, or moderate volume-low intensity group, with 35 participants in each group. Participants will be required to conduct two experiments. The first was the familiarity experiment, which consisted of the experiment description, the familiarity test, and the 6 Repetition Maximum (RM) test. The process lasted about 3 hours. The exercise group was given a warm-up exercise before the intervention, followed by resistance exercise, including Bench Press, Rowing, Deadlift, and Squat, all completed on the Smith machine. After the exercise, the group was given a cool down, while the control group was given 30 minutes of reading. Before and after the intervention, Stroop, event-related potential and fingertip blood lactate were measured, and another fingertip blood lactate was measured 10 minutes after the intervention, which lasted about 3 hours.

Eligibility criteria: Inclusion Criteria:

* The dominant hand is right-handed
* 18.5 \< BMI \< 26
* Can cooperate with fingertip blood collection
* No color blindness and epilepsy
* Not taking medications that affect brain function
* Irregular exercise (more than 150 minutes per week for 3 months)

Exclusion Criteria:

* The participants who do not meet the inclusion or The Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) Criteria.

Primary outcomes:
measure: Changes In Inhibitory Control
timeFrame: 30 minutes each before & after intervention
measure: Changes In Neuroelectrical Activities: Event-Related Potential Recording and Analysis
timeFrame: 30 minutes each before & after intervention
Secondary outcomes:
measure: Changes In Positive & Negative Affect
timeFrame: 5 minutes after pre-test and post-test of Stroop test
measure: Muscular Fitness Measurements (1RM)-Deadlift
timeFrame: 2 hours on the first day
measure: Muscular Fitness Measurements (1RM)-Bench Press
timeFrame: 2 hours on the first day
measure: Muscular Fitness Measurements (1RM)-Squat
timeFrame: 2 hours on the first day
measure: Muscular Fitness Measurements (1RM)-Rowing
timeFrame: 2 hours on the first day
measure: Changes In Concentration Of Blood Lactate
timeFrame: 2 minutes of each time point (Before the pre-test of cognitive test, after the intervention and before the post-test of cognitive test)
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: National Taiwan Normal University
Study officials:
affiliation: Department of Physical Education and Sport Sciences, National Taiwan Normal University
name: Yu-Kai Chang, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: