Clinical trial NCT03368768: Antibiotic Footprint Thailand - Pilot Questionnaire Study
Official title: Antibiotic Footprint Thailand - Pilot Questionnaire Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Antibiotic Usage
Keywords: Antimicrobial-resistant bacterial infection
Questionaire
Lead sponsor: University of Oxford
Sponsor class: OTHER
First posted: 2017-12-11
Enrollment: 237
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: This study aims to have at least 100 adult people who could provide information for the total of one year. This expects that at least 20 of those 100 people would have common cold or diarrhea at least one time over one year period. This should provide more than 80% power to detect whether the proportion of having antibiotics when they have common cold or diarrhea was lower than 50% or not. The hypothesizjed proportion was 20% as stated by the national strategy against AMR in Thailand.

MORU has a total number of staff for more than 200 people, and we suspect that the internal people in MORU should be enough for the study. We will also want to pilot whether the internet-based study can spread into the community well or not.

Brief summary: Antimicrobial-resistant bacterial infection is an important cause of death in Thailand and in other countries worldwide. Increasing use of antibiotics in both animals and humans is one of the main drive that increase the incidence of antimicrobial resistant bacteria in human, animals and environment.

National Action Plan for Combating Antibiotic-resistant Bacteria aimed to have general population taking antibiotics less than 20% when they have common cold or diarrheal symptoms. However, there is little accurate information about behaviors of Thai people. Most studies were conducted in hospitals, clinics or pharmacy. Therefore, it did not include behaviors of those who had symptoms but did not present at hospitals, clinics or pharmacy.

In this study, the investigators aim to use questionnaire to Thai adult population to ask for the the amount of antibiotic used and the periods they had symptoms of common cold or diarrhea over one year period of year 2017. The main aim is to estimate the total antibiotic usage per human population, and plan for the study in the future.


Eligibility criteria: Inclusion Criteria:

The participant may enter the study if ALL of the following apply:

1. Participant is willing and able to give informed consent for participation in the study.
2. Male or female, aged 18 years or above.
3. Living in Thailand (staying in Thailand more than 6 months per year)

Exclusion Criteria:

None

Primary outcomes:
measure: Total antibiotic usage in human population
timeFrame: 1 year
Secondary outcomes:
measure: Association between the antibiotic usage and the episodes of common cold
timeFrame: 1 year
measure: Association between the antibiotic usage and the episodes of diarrhea
timeFrame: 1 year
Other outcomes:
Locations:
city: Bangkok
country: Thailand
facility: Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, Thailand
Study officials:
References: