Clinical trial NCT06724484: Post-operative Anxiety and Depression Among Older Adults Who Undergo Surgery for Fragility Fractures
Official title: Post-operative Anxiety and Depression Among Older Adults Who Undergo Surgery for Fragility Fractures
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Fractures in the Elderly
Keywords: Fragility fracture
Anxiety
Depression
Surgery
Lead sponsor: University of Southampton
Sponsor class: OTHER
First posted: 2024-12-09
Enrollment: 60
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Older adults who are admitted to a tertiary hospital/ major trauma centre with a fragility fracture.

Brief summary: Patients who present with falls and fractures can experience increased symptoms of depression and anxiety due to the trauma of falling, hospitalisation and surgery. Additionally after surgery, patients may be limited in their mobility, resulting in a loss in their independence which can lead to further feelings of frustration and helplessness. In this study we want to know how common this problem is among older people who are admitted to hospital with broken bones and subsequently receiving surgery.

We will use a questionnaire called the Hospital Anxiety and Depression Scale (HADS) to explore this. We will recruit 60 patients for this study, 30 participants who received operative management and a further 30 participants who did not receive surgery for comparison. Patients who are not able to consent to the study or those who are not able to complete the questionnaire will not be recruited. We will collect routine data from the patients to provide a description of the patients that we are studying. Patients will complete the HADS questionnaire once during their hospital stay and then in 1 month's time. We will contact patients through telephone for the 1 month follow up.

This study will enable us to determine how common are the symptoms of anxiety and depression among this group of patients. This will help raise awareness of the problem which may prompt further intervention and management plan to address this important issue.


Eligibility criteria: Inclusion Criteria:

* Age 65 years and above
* Received operative or non-operative management of fragility fracture
* Able to provide written consent

Exclusion Criteria:

* Patients receiving end of life care
* Patients with known diagnosis of severe dementia and/ or lack capacity to consent
* Non-fragility fracture

Primary outcomes:
measure: Hospital Anxiety and Depression Scale
timeFrame: This will be measured at baseline and at 1 month follow up.
Secondary outcomes:
Other outcomes:
Locations:
city: Southampton
country: United Kingdom
facility: Academic Geriatric Medicine, University of Southampton
state: Hampshire
Study officials:
affiliation: University of Southampton
name: Stephen Lim, BM, MRCP (UK), PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Frenkel WJ, Jongerius EJ, Mandjes-van Uitert MJ, van Munster BC, de Rooij SE. Validation of the Charlson Comorbidity Index in acutely hospitalized elderly adults: a prospective cohort study. J Am Geriatr Soc. 2014 Feb;62(2):342-6. doi: 10.1111/jgs.12635. Epub 2014 Jan 21.