Clinical trial NCT03126084: Postoperative Effects of TAP Block Versus QLB Type 2 Block
Official title: Comparison of Postoperative Analgesic Effects of Transversus Abdominis Plane Block and Quadratus Lumborum Block Type 2
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Inguinal Hernia
Postoperative Pain
Lead sponsor: Bozyaka Training and Research Hospital
Sponsor class: OTHER
First posted: 2017-04-24
Enrollment: 90
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study compares analgesic effectiveness of transversus abdominis plane block and quadratus lumborum block type 2 in open hernia repair surgery. All of the patients will receive routine intravenous analgesic regimen. In addition to that one-third of the patients will receive transversus abdominis plane block, one-third will receive quadratus lumborum block type 2. One-third of the patients will not receive any blocks and will constitute the control group


Eligibility criteria: Inclusion Criteria:

* Patients who are over 18 years of age
* Patients who are scheduled for elective unilateral open hernia repair with tension free mesh techniques
* Patients who are in ASA's physical status score group 1 or 2

Exclusion Criteria:

* Patients who are younger than 18 years of age
* Patients who have severe stenotic heart diseases
* Patients who have bleeding diathesis
* Patients who have true allergies to local anesthetics
* Patients who have neurologic deficits corresponding to effect site of the anesthetic techniques

Primary outcomes:
measure: Pain Intensity
timeFrame: 24 hours after surgery
measure: Pain Intensity
timeFrame: 2 hours after surgery
measure: Pain Intensity
timeFrame: 6 hours after surgery
measure: Pain Intensity
timeFrame: 48 hours after surgery
Secondary outcomes:
Other outcomes:
Locations:
city: Izmir
country: Turkey
facility: Izmir Bozyaka Training and Research Hospital
Study officials:
affiliation: Izmir Bozyaka Training and Research Hospital
name: Zeki T TEKGUL, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: McDonnell JG, O'Donnell B, Curley G, Heffernan A, Power C, Laffey JG. The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial. Anesth Analg. 2007 Jan;104(1):193-7. doi: 10.1213/01.ane.0000250223.49963.0f. Erratum In: Anesth Analg. 2007 May;104(5):1108.
citation: Baerentzen F, Maschmann C, Jensen K, Belhage B, Hensler M, Borglum J. Ultrasound-guided nerve block for inguinal hernia repair: a randomized, controlled, double-blind study. Reg Anesth Pain Med. 2012 Sep-Oct;37(5):502-7. doi: 10.1097/AAP.0b013e31825a3c8a.
citation: Finnerty O, Carney J, McDonnell JG. Trunk blocks for abdominal surgery. Anaesthesia. 2010 Apr;65 Suppl 1:76-83. doi: 10.1111/j.1365-2044.2009.06203.x.
citation: Okur O, Karaduman D, Tekgul ZT, Koroglu N, Yildirim M. Posterior quadratus lumborum versus transversus abdominis plane block for inguinal hernia repair: a prospective randomized controlled study. Braz J Anesthesiol. 2021 Sep-Oct;71(5):505-510. doi: 10.1016/j.bjane.2020.11.004. Epub 2021 Feb 10.