louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02279069: 4-point vs 4-roll Canne as Walking Aids After Stroke
Official title: Comparison Between Classical 4-point Canne and 4-roll Canne on Gait Parameters (Gait Speed and Energy Cost) as Walking Aids After Stroke. A Multicentric Randomized Controled Cross-over Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: stroke
walking
rehabilitation
Lead sponsor: University Hospital of Mont-Godinne
Sponsor class: OTHER
First posted: 2014-10-30
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: Stroke patients frequently necessitate walking aids such as 4-point canne. However, the 4-point canne has to be lifted by the patient which limited gait speed. The adjunction of small wheel below the 4 point of the canne (4-roll) gives the possibility to the patient to walk without having to lift the canne as it will roll over the ground.

The aim of our study is to compare gait parameters (gait speed and energy cost) with a classical 4-point canne and with 4-roll canne.

Detailed description: Stroke patients frequently need walking aids such as 4-point canne. However, the 4-point canne has to be lifted by the patient which limited gait speed. The adjunction of small wheel below the 4 point of the canne (4-roll) gives the possibility to the patient to walk without having to lift the canne as it will roll over the ground.

OBJECTIVE To compare the gait parameters with a 4-point canne and with a 4-roll canne METHODS The investigators will recruited stroke patients who necessitate 4 point-canne as walking aids. A 10 meters walking test, a 6 minutes walking test, an estimated energy cost and a patient's satisfaction will be monitored with a 4-point canne (day 1) and with a 4-roll canne (day 2) in a cross-over study. The first tested device will be randomized.

PERSPECTIVE The investigators hope to demonstrate that a 4-roll canne makes possible to walk faster in a safe way after stroke

Eligibility criteria: Inclusion Criteria:

* post stroke patient
* able to walk 10 meters

Exclusion Criteria:

* cognitive impairment limiting walking capacities
* need support when walking

Primary outcomes:
measure: 10 meters walking test at spontaneous speed
timeFrame: 2 days
Secondary outcomes:
measure: 10 meters walking test at fast speed
timeFrame: 2 days
measure: 6 minutes walking test
timeFrame: 2 days
measure: Borg scale for perceived exertion
timeFrame: 2 days
measure: Visual analogic scale for personal satisfaction
timeFrame: 2 days
measure: Energy cost
timeFrame: 2 days
Other outcomes:
Locations:
city: Yvoir
country: Belgium
facility: Deltombe Thierry
Study officials:
affiliation: CHU Dinant Godinne / UcL Namur
name: Thierry Deltombe, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Centre Neurologique William Lennox Ottignies
name: Geoffroy Dellicour, PT
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04247269: Review of Enteral Formulas in Children
Official title: Retrospective Review of Enteral Formulas in Medically Complex Children
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Enteral Feeding Intolerance
Tube Feeding
Nutrition Disorder, Child
Lead sponsor: Société des Produits Nestlé (SPN)
Sponsor class: INDUSTRY
First posted: 2020-01-30
Enrollment: 0
Sex: ALL
Minimum age (years): 1
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Population studied retrospectively will be children with a history of enteral tube feeding in a home setting and meeting inclusion/exclusion criteria

Brief summary: Retrospective review of nutrition enteral formula data documented in medical records.

Detailed description: This is a retrospective review to assess nutrition (calorie and protein) intake of enteral formula data documented in medical records of patients that consumed enteral tube feeding formulas at home.

Eligibility criteria: Inclusion Criteria:

* Minimum 12 months enteral feeding
* History of enteral feeding with intact or semi-elemental formula

Exclusion Criteria:

* Medical records lacking enteral nutrition feeding use

Primary outcomes:
measure: Nutrition Intake
timeFrame: 12 months
Secondary outcomes:
measure: Body weight
timeFrame: 12 months
measure: Length/height
timeFrame: 12 months
measure: Formula volume consumption
timeFrame: 12 months
measure: Stool frequency
timeFrame: 12 months
measure: Ventilator status
timeFrame: 12 months
Other outcomes:
Locations:
city: Columbus
country: United States
facility: Central Ohio Specialty Care
state: Ohio
Study officials:
affiliation: Société des Produits Nestlé (SPN)
name: Krysmaru AraujoTorres, MD
role: STUDY_DIRECTOR
References:
Clinical trial NCT03417869: QuickVue Influenza A + B Test Field Study
Official title: QuickVue Influenza A + B Test Field Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Influenza A, Influenza B
Lead sponsor: Quidel Corporation
Sponsor class: INDUSTRY
First posted: 2018-01-31
Enrollment: 1381
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Subjects will be recruited from the general population as they present to the clinical facility. Subjects must have had a fever within the last two days and exhibiting one or more symptoms characteristic of influenza

Brief summary: Demonstrate improved clinical performance of visually read QuickVue Influenza A+B test.

Detailed description: The objective of this study is to demonstrate an improved clinical performance of the visually read QuickVue Influenza A+B test with nasal and nasopharyngeal swab specimens. Clinical performance will be based on comparison of QuickVue results to either cell culture or an FDA-cleared molecular test at one or more Reference Laboratories.

Eligibility criteria: Inclusion Criteria:

Subjects will be recruited from the general population as they present to the clinical facility. Subjects must have had a fever within the last two days and exhibiting one or more symptoms characteristic of influenza. They must meet the following criteria to be eligible for enrollment:

1. Male or Female of all ages (with appropriate consent).
2. The subject must have had of a fever, ≥ 37.8º C (100º F), within the last two days.
3. Must also be currently exhibiting one or more of the following symptoms characteristic of influenza-like-illness (ILI).

   1. Nasal congestion
   2. Rhinorrhea
   3. Sore throat
   4. Cough
   5. Headache
   6. Myalgia
   7. Malaise

Exclusion Criteria:

* 1. Has undergone treatment with anti-influenza antivirals within the previous 7 days, to include but not be limited to, Amantadine, Rimantadine, Ribavirin, Oseltamivir, Zanamivir or any other antiviral currently available in these classes.

  2. Has been vaccinated by means of an influenza nasal spray/mist vaccine within the previous 7 days.

  3. Unable to understand and consent to participation; for minors this includes parent or legal guardian.

Primary outcomes:
measure: Influenza Diagnostic test result
timeFrame: 10 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Phoenix
country: United States
facility: Alliance Urgent Care
state: Arizona
city: Rochester
country: United States
facility: Twelve Corners Pediatrics
state: New York
city: Belton
country: United States
facility: Veritas, P.A.
state: Texas
city: Dallas
country: United States
facility: City Doc Urgent Care
state: Texas
city: Vienna
country: United States
facility: Advanced Pediatrics
state: Virginia
Study officials:
References:
Clinical trial NCT04377269: Short-Term and Long-Term Effects of Ankle Joint Taping and Bandaging on Balance, Proprioception and Vertical Jump Among Volleyball Players With Chronic Ankle Instability
Official title: Short-Term and Long-Term Effects of Ankle Joint Taping and Bandaging on Balance, Proprioception and Vertical Jump Among Volleyball Players With Chronic Ankle Instability
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Ankle Instability
Lead sponsor: Istanbul Gelisim University
Sponsor class: OTHER
First posted: 2020-05-06
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Objective: This study aimed to 1) investigate the long-term effect of taping and bandaging on proprioception, balance, and vertical jump among volleyball players with ankle instability, 2) Compare the short-term effects of taping and bandaging on these outcome measures, 3) Compare the long-term effects of taping and bandaging on these outcome measures.

Design: A single-blinded randomized controlled study Setting: Rehabilitation Laboratory at Istanbul Gelisim University, Turkey Subjects: One-hundred participants with a chronic ankle sprain (CAI) Primary outcome measures: Proprioception (ankle range of motion absolute error), balance(Y-balance test), and vertical jump (vertical jump tester) Interventions: Participants were distributed into three groups: taping group (n=33) received ankle rigid taping, bandaging group (n=33) received ankle bandaging, and control group (n=34) received placebo taping. All three previous external supports were applied for 8 weeks. The measurements were performed at baseline, immediately after applying for support, two weeks after support and eight months after support.


Eligibility criteria: Inclusion Criteria:

* Volleyball Player
* 18-30 years old
* Athletes with chronic ankle instability

Exclusion Criteria:

* Previous hip/pelvis knee, or foot surgery within the past year
* Leg length discrepancies
* Known balance impairment due to neurological disorder
* Vestibular disorder
* Pregnancy
* Brain concussion within the previous three months
* Taking any medication that may affect alertness or balance

Primary outcomes:
measure: Proprioception
timeFrame: 2 Months
measure: Balance
timeFrame: 2 Months
measure: Vertical Jump Distance
timeFrame: 2 Months
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT04301869: Oral Versus Intravenous Antibiotics for the Treatment of Pleural Space Infection: a Randomized Controlled Pilot Trial
Official title: Oral Versus Intravenous Antibiotics for the Treatment of Pleural Space Infection: a Randomized Controlled Pilot Trial
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Pleural Infection
Lead sponsor: St. Joseph's Healthcare Hamilton
Sponsor class: OTHER
Collaborators: name: Vaibhav Mokashi
First posted: 2020-03-10
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: We aim to conduct a pilot trial assessing oral versus intravenous therapy for pleural space infections.

Detailed description: Pleural space infections are a frequent clinical problem resulting in significant morbidity and mortality as well as healthcare cost. Despite the increasing burden of disease, there are no clinical trials evaluating antibiotic therapy in pleural space infections. Hence, British and American guidelines are only able to provide weak and vague recommendations regarding duration, type or route (intravenous or oral) of antibiotic therapy. Our goal is to determine whether oral (PO) therapy is non-inferior to intravenous (IV) therapy thereby decreasing risks of IV catheter related infections, vein thrombosis and health care costs. Similar studies have been successfully conducted in the setting of bone/joint infections and endocarditis and showed non-inferiority of oral antibiotics. However, in order to help ensure that the randomized trial is of good quality, it is important to assess the feasibility of such a trial by first conducting a pilot study. The goal of this pilot trial is to assess the feasibility of the proposed study design.

Eligibility criteria: Inclusion Criteria:

* Must meet our study definition of pleural space infection
* Age \> or = 18 years old
* Life expectancy \> 1 year
* Received intravenous or oral antibiotics for = or \< 7 d from surgical intervention or received a total of = or \< 7 d of antibiotics if no intervention performed

Exclusion Criteria:

* S. aureus bacteremia or endocarditis in the last 1 month
* Another concomitant infection requiring prolonged IV antibiotics
* Esophageal rupture or malignant pleural effusion
* Septic shock or systemic features requiring IV antibiotics
* Mycobacterial, fungal or parasitic pleural space infection
* No oral antibiotic options available
* Unlikely to comply with therapy

Primary outcomes:
measure: Enrollment feasibility
timeFrame: 3 months
measure: Completion feasibility
timeFrame: 3 months
Secondary outcomes:
measure: Treatment failure
timeFrame: 3 months
measure: Mortality
timeFrame: 3 months
measure: Antibiotic duration
timeFrame: 3 months
measure: Hospitalization duration
timeFrame: 3 months
measure: Stopping antibiotics
timeFrame: 3 months
measure: IV line complications
timeFrame: 3 months
measure: C. difficile
timeFrame: 3 months
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT06140069: Voluntary Termination of Pregnancy: Comparison of Women's Experiences Depending on the Method Used.
Official title: Voluntary Termination of Pregnancy Between 14 and 16 Weeks of Amenorrhea: Comparison of Women's Experiences Depending on the Method Used, Surgical or Medicinal.
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Voluntary Termination of Pregnancy
Lead sponsor: University Hospital, Toulouse
Sponsor class: OTHER
First posted: 2023-11-18
Enrollment: 0
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient coming for Voluntary termination of pregnancy (abortion)

Brief summary: Voluntary termination of pregnancy (abortion) is a major current societal issue. This is a very common situation, around 225,000 abortions are carried out every year in France. The French law of March 2, 2022 (no. 2022-295) extended the legal deadline for voluntary termination of pregnancy from 14 to 16 weeks of amenorrhea (SA). The recommendations have not been updated following this legal extension, the centers performing abortions are therefore free regarding the protocol for carrying out these so-called late abortions (between 14 and 16 weeks). There are two pregnancy termination techniques practiced in France: medical or surgical. The drug method consists of drug-induced expulsion of the pregnancy. This method is carried out in the delivery room, and lasts several hours. The surgical method consists of an endouterine aspiration carried out in the operating room, which lasts approximately 30 minutes. At the Toulouse University Hospital, as in many centers in France, it is the patient who chooses the method, apart from a contraindication to one or other of these methods. Due to the recent nature of these late abortions, practitioners still have little experience of the consequences of these procedures and this compromises the quality of the information provided to patients. It is necessary to have quality studies to improve knowledge about late abortions, in order to be able to correctly inform patients and allow them to make an informed choice regarding the method used.


Eligibility criteria: Inclusion Criteria:

* Any adult patient
* Having given her non-opposition after clear and fair information (patient who understands and reads French)
* Patient treated at the Toulouse University Hospital for an abortion between 14 and 16 weeks (dating by ultrasound)
* Singleton pregnancy
* Progressive pregnancy

Exclusion Criteria:

* Protected adult patient (guardianship, curatorship, protection of justice)
* Developing psychiatric pathologies
* Fetal anomaly detected

Primary outcomes:
measure: Evaluation of anxiety or depressive disorder depending on the method used, surgical or medicinal
timeFrame: At the inclusion visit before abortion and 3 weeks after abortion
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: CHU Toulouse
name: Lola LOUSSERT CHAMBRE, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06899269: SPAROBOPAN Project (Spanish Registry of Robotic Pancreatic Surgery)
Official title: Proyecto SPAROBOPAN (Registro Nacional De Cirugía Róbotica Pancreática)
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Robotic Surgical Procedures
Pancreatic Diseases
Lead sponsor: Hospital General Universitario de Alicante
Sponsor class: OTHER
First posted: 2025-03-27
Enrollment: 225
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient who will undergo robotic pancreatic resections

Brief summary: Pancreatic robotic surgery (PRS) has moved from an almost testimonial procedure to a moment of expansion that is not yet clearly defined. In the pioneering centres, the results achieved are superior to those of open surgery. At present, it is not known how many centres perform CRP, what type of operations they perform, what percentage of the total number of pancreatic operations CRP represents and what results are obtained. The aim of our project is to establish a national multicentre registry of robotic pancreatic surgery that will allow us to answer all these questions.

Methodology: This is a one-year prospective multicentre registry involving all general and digestive surgery units in Spain that have a DaVinci robotic platform and wish to participate and perform robotic pancreatectomies.

All adult patients undergoing robotic pancreatectomy at participating Spanish centres who meet the inclusion criteria will be included. The registry will be open until 31 March 2026 to include post-operative morbidity and mortality at 90 days. The number of pancreatic surgeries performed in that centre during the same period will be counted to determine the percentage of robotic pancreatic surgery per centre. Intraoperative complications will be measured according to the Satava classification modified by Halls et al. Postoperative complications will be classified according to the Clavien-Dindo classification and the CCI (Comprehensive Complication Index). Pancreatic fistula, postoperative bleeding and delayed gastric emptying were classified according to the ISGPS classification and biliary fistula according to the ISGLS classification.


Eligibility criteria: Inclusion Criteria:

* robotic pancreatic resections
* Asa I-III
* Signed informed consent

Exclusion Criteria:

* Less than 18 years old.
* ASA IV

Primary outcomes:
measure: Postoperative complications
timeFrame: 90 postoperative days
measure: Postoperative complications
timeFrame: 90 postoperative days
measure: Number of robotic procedures
timeFrame: 1 year
Secondary outcomes:
measure: Experience of each group in robotic pancreatic surgery
timeFrame: 1 year
measure: Textbook outcome
timeFrame: 1 year
measure: Total survival
timeFrame: 3 years
measure: Disease-free survival
timeFrame: 3 years
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT04079569: Empower Korean Families to End Tobacco Use & Smoking Exposure
Official title: Empower Korean Families to End Tobacco Use & Smoking Exposure
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Smoking Cessation
Lifestyle Risk Reduction
Keywords: tobacco
smoking cessation
Asian Americans
Lead sponsor: University of California, San Francisco
Sponsor class: OTHER
Collaborators: name: Korean Community Center of the East Bay
First posted: 2019-09-06
Enrollment: 112
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The goals of the study are to develop a culturally and linguistically appropriate intervention to promote smoking cessation and reduce secondhand smoke exposure for Korean Americans using a family-based intervention approach targeting Korean Americans ages 18 and above in the greater San Francisco Bay Area, CA, and to evaluate efficacy of the proposed intervention. The study is a randomized control trial targeting a total of 8 lay health workers (LHW) and 48 dyads of a daily smoker and a partner who will attend intervention sessions together. The research question is: Can a family-based lay health worker outreach intervention promote smoking cessation and reduce SHS exposure among Korean Americans?


Eligibility criteria: Inclusion Criteria:

* reside in California, United States
* for the smoker participants, they must have smoked at least 1 cigarette in the past 30 days, and have smoked either at least 1 cigarette and/or used e-cigarettes in the past 7 days, and self-identified as Korean or Korean American
* for partner participants, they must be willing to attend intervention session together with a smoker participant
* provide a valid contact telephone number and email address for pre- and post-intervention assessments

Primary outcomes:
measure: Abstinence
timeFrame: 3 months
measure: Secondhand smoke (SHS) exposure of non-smokers
timeFrame: 3 months
measure: Percent attendance
timeFrame: 3-month
measure: Percentage of participants who rate the intervention as helpful
timeFrame: 3 months
Secondary outcomes:
measure: Number of Quit attempts
timeFrame: 3 months
Other outcomes:
Locations:
city: San Leandro
country: United States
facility: Korean Community Center of the East Bay
state: California
Study officials:
affiliation: University of California, San Francisco
name: Janice Y Tsoh, PhD
role: PRINCIPAL_INVESTIGATOR
References: