Clinical trial NCT05768555: Whole Body Vibration Training Applied with Different Frequencies in Hypertensive Patients
Official title: Investigation of the Effects of Single Session Whole Body Vibration Training Applied with Different Frequencies in Hypertensive Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hypertension
Keywords: hypertension
whole body vibration
Lead sponsor: Dokuz Eylul University
Sponsor class: OTHER
First posted: 2023-03-14
Enrollment: 36
Sex: ALL
Minimum age (years): 40
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: At least 36 volunteers with a diagnosis of hypertension in the Department of Cardiology of Dokuz Eylul University and who meet the criteria for follow-up and inclusion will participate in the study. The aim of this study is to compare the acute effects on atherosclerosis, heart rate variability, blood pressure, perceived exertion, energy expenditure, and muscle strength of using different frequencies in whole body vibration training (WBVT) in hypertensive patients. Individuals will perform; static squat, dynamic toe raise, static abduction and dynamic squat exercises in both hips on a vibrating platform. In each session, a different frequency (0,25 and 40 Hz) will be applied. 0 Hz, 25 Hz and 40 Hz sessions will be randomized to last 15 minutes. Demographic and clinical information of the participants will be questioned.Before and after the sessions; hemodynamic and pulmonary responses, vascular responses, heart rate variability and quadriceps femoris muscle strength will be measured. In addition, energy expenditure will be recorded during the sessions.

Detailed description: Hypertension is one of the most common chronic diseases and it is an important global public health problem. In cardiac rehabilitation programs, aerobic exercise, resistance exercise and a combination of aerobic and resistance exercise are recommended to reduce cardiovascular risk. Whole body vibration training has also started to be used among new applications in the cardiac rehabilitation programs. Whole body vibration training has been reported as an effective and safe approach for both healthy and cardiovascular diseased women and men. It has been shown to be beneficial in improving atherosclerosis and blood pressure in hypertensive patients. In whole body vibration training, frequencies of 20-40 Hz are generally used for hypertensive elderly patients. However, the optimal frequency in this population has not been fully determined. For these reasons, the aim of the study is to compare the acute effects of using different frequencies in whole body vibration training in hypertensive patients.

Whole body vibration intervention will be performed with the Power Plate Pro 5 device (Power Plate International, London, UK). Whole body vibration training will be performed at three different frequencies (0, 25 and 40 Hz). Each patient will complete the training in these 3 frequencies in random order and on different days. Before and after the sessions; hemodynamic and pulmonary responses, vascular responses, heart rate variability and quadriceps femoris muscle strength will be measured. In addition, energy expenditure will be recorded during the sessions.Individuals will perform; static squat, dynamic toe raise, static abduction and dynamic squat exercises in both hips on a vibrating platform. All exercises will consist of 45 seconds of vibration and 15 seconds of rest. Each exercise will be repeated three times. Total intervention time will be 15 minutes. Participants will perform whole body vibration trainings at different frequencies in a randomized order with at least one day apart.

Eligibility criteria: Inclusion Criteria:

* Being diagnosed with hypertension
* Being clinically stable
* Becoming a volunteer
* Walking independently
* Not taking medication or hormone therapy in the year before the study
* Lack of regular exercise habit (\<60 minutes/week of exercise)

Exclusion Criteria:

* Having a serious cardiovascular/pulmonary condition
* Having an operation in the last 6 months
* Presence of acute thrombosis
* Presence of arrhythmia
* Presence of unstable angina
* Recent decompensated heart failure
* Recent myocardial infarction
* Using an assistive device to walk
* Neurological disorders (such as stroke, Parkinson's)
* Being diagnosed with vertigo
* Being diagnosed with epilepsy
* Kidney failure and history of kidney stones
* Hip or knee implants
* Recent fractures or injuries (\<6 months).
* Using a prosthesis
* Pregnancy
* Participation in any training program in the 3 months before study

Primary outcomes:
measure: Arterial stiffness
timeFrame: Change from the baseline to the first minutes after the intervention
measure: Heart rate variability
timeFrame: Change from the baseline to the first minutes after the intervention
measure: Blood pressure
timeFrame: Change from the baseline to the first minutes after the intervention
Secondary outcomes:
measure: Muscle strength
timeFrame: Change from the baseline to the first minutes after the intervention
measure: Energy expenditure
timeFrame: During exercise intervention, average 15 minutes
measure: Heart rate
timeFrame: Change from the baseline to the first minutes after the intervention
measure: Perceived effort
timeFrame: Change from the baseline to the first minutes after the intervention
measure: Respiratory frequency
timeFrame: Change from the baseline to the first minutes after the intervention
Other outcomes:
Locations:
city: İzmir
country: Turkey
facility: Dokuz Eylül University
state: Balçova
Study officials:
affiliation: Dokuz Eylul University
name: Sema Savcı
role: STUDY_DIRECTOR
References: