Clinical trial NCT03531138: Is it Possible to Use the Timed Performance Tests in Lung Transplantation Candidates to Determine the Exercise Capacity?
Official title: Is it Possible to Use the Timed Performance Tests in Lung Transplantation Candidates to Determine the Exercise Capacity?
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pulmonary Rehabilitation
Exercise Capacity
Exercise Test
Keywords: performance test
exercise capacity
rehabilitation outcome
pulmonary rehabilitation
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2018-05-21
Enrollment: 43
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: Lung transplantation candidates will be performed a 3-month hospital-based preoperative exercise training. A 6-minute walk test, a 10-meter walking speed test and a 5-times sit to stand test will be performed to determine the exercise capacity of the patient. The tests will be carried out at the beginning and end of rehabilitation. At each testing session, the tests will be performed sequentially by the same physiotherapist, giving 20 minute rest periods within the same day. It will be analyzed how the test data correlate with each other and how the delta values calculated for each test reflect the rehabilitation outcomes calculated after the exercise program.

Detailed description: Severe exercise intolerance exists in lung transplant candidates. Completion of the test period in the field tests used in determining the exercise capacity of these patients is extremely difficult. The exercise capacity, which is considered as an important criterion in the decision of the lung transplant decision and in the determination of the clinical profile of the patient, necessitates the development of different test methods which are more suitable for the application of the measurement in this patient population.

In this study lung transplantation candidates will be performed a 3-month hospital-based preoperative exercise training. A 6-minute walk test, a 10-meter walking speed test and a 5-times sit to stand test will be performed to determine the exercise capacity of the patient. The tests will be carried out at the beginning and end of rehabilitation. At each testing session, the tests will be performed sequentially by the same physiotherapist, giving 20 minute rest periods within the same day. It will be analyzed how the test data correlate with each other and how the delta values calculated for each test reflect the rehabilitation outcomes calculated after the exercise program.

Eligibility criteria: Inclusion Criteria:

* To be taken to the list for lung transplant
* Do not have any addiction that may interfere with exercise

Exclusion Criteria:

-Do not accept to study

Primary outcomes:
measure: Change from baseline distance covered in six minute walking test at 3-months
timeFrame: 3-months
measure: Change from baseline 10-meter walking speed test at 3-months
timeFrame: 3-months
measure: Change from baseline 5 times sit to stand test at 3-months
timeFrame: 3-months
Secondary outcomes:
measure: Change from baseline Modified Medical Research Council (mMRC) Dyspnea Scale score at 3-months
timeFrame: 3-months
measure: Change from baseline Maximum Inspiratory Pressure (MIP) at 3-months
timeFrame: 3-months
measure: Change from baseline Forced Expiratory Volume in 1 second (FEV1) at 3-months.
timeFrame: 3-months
measure: Change from baseline quadriceps femoris muscle strength at 3-months.
timeFrame: 3-months
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Yedikule Chest Disease Hospital
state: Zeytinburnu
Study officials:
References: