louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06968403: Community Emotional Intelligence Network to Address Mental Health Among Coastal Bangladeshis
Official title: Community Emotional Intelligence Network to Address Mental Health Among Coastal Bangladeshis
Study type: INTERVENTIONAL
Overall status: ENROLLING_BY_INVITATION
Phase: NA
Conditions: Mental Health Conditions
Lead sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Sponsor class: OTHER
Collaborators: name: Grand Challenges Canada
name: Centre for Injury Prevention and Research Bangladesh
name: University of Dhaka, Bangladesh
name: North South University, Bangladesh
First posted: 2025-05-13
Enrollment: 1500
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: The goal of this clinical trial is to learn if the community emotional intelligence network can improve mental health outcomes in coastal Bangladeshis affected by climate change and frequent natural disasters. The main questions it aims to answer are:

* Can enhancing emotional intelligence (e.g., self-awareness, empathy, emotional regulation, etc) improve the mental health of coastal Bangladeshis?
* Does the community emotional intelligence network increase resilience and coping strategies during climate-induced mental health crises? If there is a comparison group: NA

Participants will:

* Complete a pretested questionnaire focusing on socio-demographic characteristics, mental health impacts, and climate-change related stressors and perceptions
* Attend emotional intelligence training sessions focusing on self-awareness, self-regulation, empathy, and interpersonal skills
* Participate in follow-up assessments to evaluate mental health changes, emotional intelligence growth, and overall resilience
* Engage with a mobile app to facilitate communication, learning resources, and connection with other community members.


Eligibility criteria: Inclusion Criteria:

* - Aged 18 to 50 years
* Living in the selected study area for at least 6 months.
* Giving consent to participate in the intervention and follow-up.

Exclusion Criteria:

* Disability that hampers effective communication, either verbal or non-verbal.
* Undergoing end-stage illness depending on life-saving measures or palliative care.

Primary outcomes:
measure: Mental Well being
timeFrame: 8 weeks after completion of two-day intervention
measure: Climate change related mental health status (Climate change anxiety scale)
timeFrame: 8 weeks after completion of two-day intervention
measure: Climate change related mental health status(Solastalgia scale;part of Environmental Distress Scale)
timeFrame: 8 weeks after completion of two-day intervention
measure: Mental Health (Depression, anxiety, stress)
timeFrame: 8 weeks after completion of two-day intervention
Secondary outcomes:
measure: Emotional Intelligence
timeFrame: 8 weeks after completion of two-day intervention
Other outcomes:
Locations:
city: Dhaka
country: Bangladesh
facility: Bangabandhu Sheikh Mujib Medical University
Study officials:
References:
Clinical trial NCT03619603: Biomarkers in Patients With Pneumonia
Official title: Biomarkers and Associated Outcomes in Patients With Pneumonia
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Pneumonia
Lead sponsor: Chongqing Medical University
Sponsor class: OTHER
First posted: 2018-08-08
Enrollment: 500
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients with pneumonia

Brief summary: To identifying biomarkers in patients with pneumonia

Detailed description: The aim of this study is to identify the biomarkers in patients with pneumonia. These biomarkers can distinguish community-acquired pneumonia, hospital-acquired pneumonia, severe pneumonia, bacterial infection, virus infection and fungal infection. Furthermore, these biomarkers can identify the efficacy of treatment in patients with different interventions.

Eligibility criteria: Inclusion Criteria: Healthy patients without any diseases -

Exclusion Criteria:Age less than 18 years

-

Primary outcomes:
measure: mortality
timeFrame: From diagnosis of pneumonia to discharge from hospital or up to 90 days, whichever came first
Secondary outcomes:
measure: severe pneumonia
timeFrame: From diagnosis of pneumonia to discharge from hospital or up to 90 days, whichever came first
measure: initial treatment failure
timeFrame: From diagnosis of pneumonia to discharge from hospital or up to 90 days, whichever came first
Other outcomes:
Locations:
city: Chongqing
country: China
facility: the First Affiliated Hospital of Chongqing Medical University
Study officials:
affiliation: First Affiliated Hospital of Chongqing Medical University
name: Jun Duan, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01730703: Why Join a Walking Program?
Official title: Why Join a Walking Program?
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Older Adults
Keywords: walking
incentives
elderly
Lead sponsor: University of Pennsylvania
Sponsor class: OTHER
First posted: 2012-11-21
Enrollment: 132
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adults ages 65 and older who are generally in good health and are not enrolled in daily walking exercise programs, and are able to provide their own verbal informed consent.

Brief summary: The purpose of this interview study is to learn why adults would join a walking program. This study involves interviews with persons who are 65 years of age or older. The interview takes approximately 25 minutes. A total of 132 people will be enrolled. This study will examine the utility or value of various potential features of an incentive-based walking program. These data will enable us to monitor and improve upon enrollment of incentive-based walking programs.


Eligibility criteria: Inclusion Criteria:

* age 65 or older
* self rated health at least good on a scale of poor, fair, good, very good, excellent
* self reports no physical reason not to exercise or health condition that would interfere with being active
* self reports able to walk at least 2 blocks without assistance or stopping not participating in a daily walking exercise program

Primary outcomes:
measure: Willingness to Participate
timeFrame: Participation in the study will include only one interview, lasting approximately 25 minutes. Willingness to participate will be assessed during this first and only interview with the participant.
Secondary outcomes:
measure: Self explicated conjoint task
timeFrame: Participation in the study will include only one interview, lasting approximately 25 minutes. The self explicated conjoint task will be assessed during this first and only interview with the participant.
Other outcomes:
Locations:
city: Philadelphia
country: United States
facility: University of Pennsylvania
state: Pennsylvania
Study officials:
affiliation: University of Pennsylvania
name: Jason Karlawish, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01399203: Contrast Medium Volume and Contrast-induced Nephropathy After Percutaneous Coronary Intervention
Official title: Contrast Medium Volume and Contrast-induced Nephropathy After Percutaneous Coronary Intervention
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Contrast Induced Nephropathy
Keywords: contrast-induced nephropathy
contrast medium
creatinine clearance
percutaneous coronary intervention
Lead sponsor: Guangdong Provincial People's Hospital
Sponsor class: OTHER
Collaborators: name: Hainan People's Hospital
name: Guangdong Medical College
First posted: 2011-07-21
Enrollment: 2000
Sex: ALL
Minimum age (years): 21
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: The investigators reviewed all consecutive patients who were undergoing percutaneous coronary intervention

Brief summary: To investigate the predictive value of the contrast media volume to creatinine clearance (V/CrCl) ratio for the risk of contrast-induced nephropathy (CIN) (i.e., within 48-72 h) and to determine a relatively safe V/CrCl cut-off value to avoid CIN in patients following PCI

Detailed description: contrast media volume to creatinine clearance (V/CrCl) ratios were obtained from consecutive consenting patients after unselective PCI. Receiver-operator characteristic (ROC) curves were used to identify the optimal sensitivity for the observed range of V/CrCl. The predictive value of V/CrCl for the risk of CIN was assessed using multivariate logistic regression.

Eligibility criteria: Inclusion Criteria:

* patients who agreed to stay in the hospital for 2-3 days after percutaneous coronary intervention
* provided written informed consent
* Creatinine Clearance:15-60ml/min

Exclusion Criteria:

* pregnancy
* lactation
* intravascular administration of an contrast medium within the previous seven days
* treatment with metformin
* aminoglycosides
* N-acetylcysteine (NAC)
* nonsteroidal anti-inflammatory drugs within the previous 48 h
* intake of nephrotoxic drugs within the previous seven days
* history of serious reactions to contrast mediums
* severe concomitant disease
* renal transplantation , or end-stage renal disease necessitating dialysis patients who died during percutaneous coronary intervention

Primary outcomes:
measure: Contrast-Induced Nephropathy
timeFrame: 48-72 h
Secondary outcomes:
measure: Major adverse clinical events
timeFrame: 1 year
Other outcomes:
Locations:
city: Guangzhou
country: China
facility: Ning Tan
state: Guangdong
Study officials:
affiliation: Guangdong Provincial People's Hospital
name: Yong Liu, MD
role: STUDY_DIRECTOR
References:
Clinical trial NCT05106803: Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern Jordan
Official title: Antibiotic Profile of Pathogenic Bacteria Isolated From Postsurgical Site Infections in Public Hospitals in Northern Jordan
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Bacterial Infections
Antibiotic Resistant Infection
Surgical Site Infection
Keywords: antimicrobial
hospital
post-surgical infection
surgery
Lead sponsor: Yarmouk University
Sponsor class: OTHER
First posted: 2021-11-04
Enrollment: 24
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: A hospital-based prospective study was carried out in Public-Teaching Hospital in northern Jordan with a total capacity of 400 beds, All patients meet the criteria of getting post-operative wound infections in different surgical wards and ICUs.

Brief summary: The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.

Detailed description: Background: Surgical site infections are hospital-acquired, vary from one hospital to another, and can cause significant postoperative morbidity, mortality, and prolonged hospital stay.

Aim: The main aim of the study was to identify the various pathogens associated with surgical site infections and their antibiotic susceptibility in a governmental hospital in northern Jordan.

Methods: Postsurgical wound samples were collected and processed in a microbiology laboratory using standard microbiological techniques. Antibiotic susceptibility tests were performed using 13 antibiotics covering the gram-positive and gram-negative bacteria using the disc diffusion test.

Eligibility criteria: Inclusion Criteria:

* Post-Surgical Wound Infection

Exclusion Criteria:

-

Primary outcomes:
measure: Positive culture
timeFrame: August 2019 to October 2019
Secondary outcomes:
measure: Gram stain and type of Bacteria
timeFrame: August 2019 to October 2019
measure: Antibiotic Susceptibility
timeFrame: August 2019 to October 2019
Other outcomes:
Locations:
city: Irbid
country: Jordan
facility: Yarmouk University
Study officials:
affiliation: Department of Clinical Sciences, Faculty Of Medicine, Yarmouk University
name: Raed M Ennab
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04475003: Health Literacy Among Caregivers of Children With IgE-mediated Allergy With Risk of Anaphylaxis
Official title: Health Literacy Among Caregivers of Children With IgE-mediated Allergy With Risk of Anaphylaxis
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Health Literacy
Anaphylaxis
Lead sponsor: Algemeen Ziekenhuis Maria Middelares
Sponsor class: OTHER
First posted: 2020-07-17
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: For each child that is known with IgE-mediated allergy with risk of anaphylaxis parents can invitate 4 Caregivers of children with IgE-mediated allergy with risk of anaphylaxis (adults, grandparents, school caregivers etc.).

Brief summary: Research on health literacy among caregivers of children with IgE-mediated allergy at risk of anaphylaxis (life-threatening allergic reaction). Health literacy is a person's ability to understand health information so that they can maintain or improve their health and quality of life (of themself and children).

The aim of the study is to test the general knowledge of anaphylaxis. Furthermore we test the extent to which caregivers consider themselves able to recognize and to treat anaphylaxis.


Eligibility criteria: Inclusion Criteria:

* caregivers of children with IgE-mediated allergy with risk of anaphylaxis (adults, grandparents, school caregivers etc.).
* minimum 18 years old.
* signed informed consent

Exclusion Criteria:

* none

Primary outcomes:
measure: General knowledge of anaphylaxis.
timeFrame: 1.5 year
Secondary outcomes:
measure: The extent to which caregivers consider themselves able to recognize and to treat anaphylaxis.
timeFrame: 1.5 year
Other outcomes:
Locations:
city: Gent
country: Belgium
facility: Algemeen Ziekenhuis Maria Middelares
state: Oost-Vlaanderen
Study officials:
affiliation: Algemeen Ziekenhuis Maria Middelares
name: Jasmine S Leus
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04755803: A Prospective Registry of Patients With Congenital Penile Anomalies
Official title: A Prospective Registry of Patients With Congenital Penile Anomalies
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Concealed Penis
Hypospadias
Phimosis
Chordee
Lead sponsor: Seoul National University Hospital
Sponsor class: OTHER
First posted: 2021-02-16
Enrollment: 32
Sex: MALE
Minimum age (years): 0
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Male patients between the ages of 0 to 18 years with congenital penile anomalies and receiving penoplasty at the institution.

Brief summary: Prospective registry and biobank in pediatric patients with congenital penile anomalies

Detailed description: According to the U.S. Center for Disease Control and Prevention, in the United States, one in 200 babies is born with congenital penile anomalies. In Korea, there is a rapid increase rate among other types of congenital anomalies from 1993 to 2010, from 0.7 to 10,000 to 9.9 per 10,000 cases. It leaves long term sequelae into adulthood even after the corrective operation has been performed. Some of the sequelae that patients experienced were difficulties in micturition, dissatisfaction with the appearance of the penis, and decreased sexual function, as well as psychosexual well-being.

Despite its high prevalence, hypospadias and related penile anomalies have no specific known etiology and mechanisms. However, numerous studies have shown that both gene and environment play a significant role in making etiologies multifactorial. Furthermore, a molecular trial shows that both genetics and environmental factors disrupt the normal development course of the phallus, or penis. Penis formation, growth, or the formation of the male urogenital system, in general, have shown to be androgen dependent. Any defect in the androgen synthesis leading to androgen deficiency or receptors may play a role, specifically, in the development of penile anomalies.

Pediatric patients between the ages of 0 to 18 years, with congenital penile anomalies and scheduled to undergo penoplasty will be enrolled. In this prospective observational study, our aims are to collect dartos fascia, which is a tissue in penile region, and examine histochemistry of the sample.

Eligibility criteria: Inclusion Criteria:

* Those with congenital penile anomalies (e.g. hypospadias, chordee, webbed penis) and receiving penoplasty at the institution.
* Those who understand the registry's content and are signed and dated by the patient (or the patient's legal guardian or representative).

Exclusion Criteria:

* Those who are unwilling to participate and do not sign the informed consent.
* Unable to read or understand Korean.

Primary outcomes:
measure: Dartos Fascia (Penile Tissue) sample collection
timeFrame: Procedure (At the time of penoplasty)
Secondary outcomes:
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
Study officials:
References:
Clinical trial NCT00897403: Blood and Tissue Sample Collection for Future Colon Cancer Biomarker Studies in Patients Undergoing Colonoscopy
Official title: Discovery of Candidate Biomarkers in Colon Cancer and Precancers Repository
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Colorectal Cancer
Health Status Unknown
Keywords: colon cancer
health status unknown
Lead sponsor: Vanderbilt University
Sponsor class: OTHER
Collaborators: name: National Cancer Institute (NCI)
First posted: 2009-05-12
Enrollment: 6446
Sex: ALL
Minimum age (years): 25
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients scheduled for colonoscopy either as routine screening or for a specific problem.

Brief summary: RATIONALE: Collecting and storing samples of blood and tissue from patients undergoing colonoscopy to study in the laboratory may help doctors learn more about colon cancer and identify biomarkers related to colon cancer in the future.

PURPOSE: This laboratory study is collecting blood and tissue samples for future colon cancer biomarker studies in patients undergoing colonoscopy.

Detailed description: OBJECTIVES:

* Collect blood and tissue samples (including polyps, abnormal growths, cancer, and normal tissue) from patients undergoing colonoscopy.

OUTLINE: Patients undergo blood and tissue sample collection during colonoscopy. Samples are stored for future biomarker proteomic profiling.

Eligibility criteria: DISEASE CHARACTERISTICS:

* Scheduled for colonoscopy as routine screening or for a specific problem

PATIENT CHARACTERISTICS:

* Not pregnant

PRIOR CONCURRENT THERAPY:

* No concurrent participation in a clinical trial to treat cancer or prevent cancer recurrence

Primary outcomes:
measure: Collection of blood and tissue
timeFrame: Pre-op & during surgery
Secondary outcomes:
Other outcomes:
Locations:
city: Nashville
country: United States
facility: Vanderbilt-Ingram Cancer Center - Cool Springs
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt-Ingram Cancer Center at Franklin
state: Tennessee
city: Nashville
country: United States
facility: Dan Rudy Cancer Center at Saint Thomas Hospital
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt-Ingram Cancer Center
state: Tennessee
Study officials:
affiliation: Vanderbilt-Ingram Cancer Center
name: Daniel C. Liebler, PhD
role: STUDY_CHAIR
References:
Clinical trial NCT01989403: Alternative and Integrative Therapy for Lumbar Disk Herniation
Official title: The Long-term Course of Patients Undergoing Alternative and Integrative Therapy for Lumbar Disk Herniation: A Prospective Observational Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Sciatica
Intervertebral Disc Disorder
Lead sponsor: Jaseng Hospital of Korean Medicine
Sponsor class: OTHER
First posted: 2013-11-21
Enrollment: 128
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: integrative hospital that offers both Western and traditional Korean medical services

Brief summary: The investigators report management of lumbar disc herniation with severe sciatic pain using an integrative complementary and alternative medicine approach with a 5 year follow-up.


Eligibility criteria: Inclusion Criteria:

* LBP with sciatica,
* A numeral rating scale (NRS) leg pain intensity of 5 or higher
* Onset within 1 year;
* Lumbar Disk Heriation confirmed by MRI;
* Written consent to attend 6 months of integrative CAM treatment and following assessment visits.

Exclusion Criteria:

* Treatment regarding the current LBP and/or sciatica (e.g. surgery, nerve block, or analgesic medication) other than the CAM treatment specified in the protocol
* Non-spinal or soft tissue problem related to back pain or sciatica (e.g. pregnancy, spinal tumor, or rheumatoid arthritis)
* History of spinal surgery, vertebral dislocation, fracture, or cancer;

Primary outcomes:
measure: Visual analogue scale for low back and leg pain
timeFrame: Changes from Baseline in Visual analogue scale at 2 weeks, 4 weeks, 8weeks, 12weeks, 20weeks, 24weeks, 1 years, 2years,3years,4years and 5years.
measure: the Oswestry Disability Index
timeFrame: Changes from Baseline in the Oswestry Disability Index at 2 weeks, 4 weeks, 8weeks, 12weeks, 20weeks, 24weeks, 1 years, 2years,3years,4years and 5years.
measure: the SF-36 Health Survey
timeFrame: Changes from Baseline in the SF-36 Health Survey at 2 weeks, 4 weeks, 8weeks, 12weeks, 20weeks, 24weeks, 1 years, 2years,3years,4years and 5years.
Secondary outcomes:
measure: Straight Leg Raise test
timeFrame: Changes from Baseline in the Straight Leg Raise test at 2 weeks, 4 weeks, 8weeks, 12weeks, 20weeks, 24weeks, 1 years, 2years,3years,4years and 5years.
measure: Adverse events
timeFrame: at 2 weeks, 4 weeks, 8weeks, 12weeks, 20weeks, 24weeks, 1 years, 2years,3years,4years and 5years.
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: Jaseng Spine and joint Research Institute
Study officials:
References: