Clinical trial NCT06253910: Comparison of Free Gingival Graft and Modified Apical Repositioning Flap Techniques
Official title: Comparison of Free Gingival Graft and Modified Apical Repositioning Flap Techniques to Create Attached Gingiva: A Long-Term (2 Year) Retrospective Study
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Periodontal Diseases
Keywords: attached gingiva
free gingival graft
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2024-02-12
Enrollment: 15
Sex: FEMALE
Minimum age (years): 34
Maximum age (years): 58
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Attached gingiva, a crucial component of the keratinized tissue, plays a vital role in preserving periodontal health. The free gingival graft (FGG) and modified apically repositioned flap (MARF) techniques are frequently used for addressing issues related to insufficient attached gingiva. The aim of this study was to compare the efficiency of the FGG and the MARF increasing the zone of attached gingiva in 2-year posttreatment.

Detailed description: The study included 15 participants who were both systemically and periodontally healthy, and these participants had a total of 21 teeth (10 for SDG and 11 for MARF). All included teeth had an attached gingiva width ranging from 0.5 mm to 1.5 mm and showed no signs of bone dehiscence. SDG and MARF methods were selected randomly (coin-to-coin). Clinical parameters recorded at baseline, third month, at first and second years were plaque index (PI), pocket probing depth (PPD), keratinized tissue width (KTW), attached gingiva width (AGW), bleeding on probing (BOP), gingival recession (GR) and clinical attachment level (CAL).

Eligibility criteria: Inclusion Criteria:

* having ≥15 permanent teeth excluding third molars,
* not using any orthodontic appliance,
* not being pregnant or breastfeeding,
* not having any uncontrolled chronic and/or auto-immune disease,
* not smoking.

Exclusion Criteria:

* having chronic and/or auto-immune disease
* smoking.

Primary outcomes:
measure: Attached gingiva width
timeFrame: Baseline, third month, first year and second years.
measure: Keratinized tissue width
timeFrame: Baseline, third month, first year and second years.
Secondary outcomes:
measure: Pocket probing depth
timeFrame: Baseline, third month, first year and second years.
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medipol University, School of Dentistry
state: Fatih
Study officials:
References:
citation: Carnio J, Camargo PM, Klokkevold PR, Pirih FQ. The Modified Apically Repositioned Flap Technique: A Long-Term (4 to 16 Years) Retrospective Study. Int J Periodontics Restorative Dent. 2018 July/August;38(4):519-524. doi: 10.11607/prd.3028. Epub 2017 Dec 15.
citation: Carnio J, Carnio AT, Pirih FQ, Cordero MG, Camargo PM. The Modified Apically Repositioned Flap Technique and Its Potential to Create Attached Gingiva in Areas with No Keratinized Tissue: A Long-Term (1 to 11 Years) Retrospective Case Series Study. Int J Periodontics Restorative Dent. 2020 Jan/Feb;40(1):103-109. doi: 10.11607/prd.4241.