Clinical trial NCT06689969: Effect of Osseodensification on the Peri-implant Condition
Official title: Evaluation of the Effect of Osseodensification on the Peri-implant Condition
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Implant Therapy
Keywords: Osseodensification
Lead sponsor: Al-Azhar University
Sponsor class: OTHER
First posted: 2024-11-15
Enrollment: 16
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to evaluate the effects of osseodensification vs. traditional implant site preparation clinically , radiographically, bio-chemically. in patients of both sexes, ages 25 to 45, who had bilaterally missed maxillary teeth. The main questions it aims to answer are :which technique was the better results give at implant placement? Researchers will compare Osseodensification maneuver in implant placement to see if implant stability increased also peri-implant tissue accurately formed or the same in traditional implant site preparation. Participants will receiving dental implants in narrow maxillary posterior ridge via small diameter implant in conventional method in first entity while in second entity implant by osseodensification technique using densah bur.


Eligibility criteria: Inclusion Criteria:

* All patients were free from any systemic diseases
* Individuals above age of 18 who have thin ridges and missing bilateral maxillary posterior teeth

Exclusion Criteria:

* Severe skeletal discrepancy.
* Para functional habits.
* Patients who had already received or lost implants in the potential implantation site.
* Smoker patients.

Primary outcomes:
measure: Implant primary stability
timeFrame: A single time point (once immediately after implant placement)
measure: Bone density
timeFrame: From enrollment to the end of treatment at 24 weeks" (at the beginning, one, three-, and six-months following implant insertion)
measure: Assessment of interleukin -6
timeFrame: From enrollment to the end of treatment at 24 weeks" (at the beginning, one, three-, and six-months following implant insertion)
measure: Assessment of Vascular endothelial growth factor
timeFrame: [Time Frame: From enrollment to the end of treatment at 24 weeks" (at the beginning, one, three-, and six-months following implant insertion)]
Secondary outcomes:
measure: Peri-implant probing depth
timeFrame: From enrollment to the end of treatment at 24 weeks" (at the beginning, three-, and six-months following implant insertion)
Other outcomes:
Locations:
city: Assiut
country: Egypt
facility: Faculty of dental medicine, Al-Azhar University (Assiut branch)
Study officials:
References:
citation: Strietzel FP, Nowak M, Kuchler I, Friedmann A. Peri-implant alveolar bone loss with respect to bone quality after use of the osteotome technique: results of a retrospective study. Clin Oral Implants Res. 2002 Oct;13(5):508-13. doi: 10.1034/j.1600-0501.2002.130510.x.
citation: Johnson RB, Serio FG, Dai X. Vascular endothelial growth factors and progression of periodontal diseases. J Periodontol. 1999 Aug;70(8):848-52. doi: 10.1902/jop.1999.70.8.848.
citation: Trisi P, Berardini M, Falco A, Podaliri Vulpiani M. New Osseodensification Implant Site Preparation Method to Increase Bone Density in Low-Density Bone: In Vivo Evaluation in Sheep. Implant Dent. 2016 Feb;25(1):24-31. doi: 10.1097/ID.0000000000000358.