Clinical trial NCT02866864: Animal Allergy in Korean Veterinary Researcher
Official title: Sensitization to Animal Allergens and Allergic Symptoms During Exposure to Animal Allergens in Korean Veterinary Researcher
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Rhinitis, Allergic
Asthma
Dermatitis, Atopic
Urticaria
Keywords: Allergen
Veterinary
Allergy
Animals
Lead sponsor: Gachon University Gil Medical Center
Sponsor class: OTHER
First posted: 2016-08-15
Enrollment: 135
Sex: ALL
Minimum age (years): 19
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Korean Veterinary Researcher

Brief summary: The investigators will evaluate sensitization to animal allergens and allergic symptom during contacting animal allergens in Korean veterinary researchers who attend their annual conference.

The investigators will compare sensitization to animal allergen and other clinical and occupational factors between subjects who suffer from allergic symptom during contacting animal and those who do not.

Detailed description: The investigators will visit annual conference of Korean veterinary researchers.

After informed consent, Korean veterinary researchers who attend their conference and agree to enrollment into this study will be asked to respond to questionnaires regarding their gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration. Subjects will also be requested to report allergic symptom, causal animal and situation of contact including veterinary service, animal experiment, pet ownership, and ingestion if subjects suffer from allergic symptom when subjects contact animal.

Then, subjects will also be asked to undergo skin prick test for animal allergens including chicken feather and ten mammal epithelia as well as cow's milk, and hen's egg, four fish flesh and seven animal meats.

subjects will be divided into two group, subjects who suffer from allergic symptom during contacting animal and those who do not. Between two groups, sensitization to animal allergens as well as other demographic and occupational factors including gender, age, underlying allergic diseases, family history of allergic diseases, occupation and it's duration, contact animal and contact duration will be compared.

Eligibility criteria: Inclusion Criteria:

* Veterinary researchers attending their annual conference

Exclusion Criteria:

* Veterinary researchers who receive medication including antihistamine (H1 and H2 blocker), systemic glucocorticosteroid which can effect on the result of skin prick test
* Veterinary researchers who do not want to participate in this study

Primary outcomes:
measure: Skin reactivity to animal allergen in skin prick test
timeFrame: on the day of survey (day 1)
Secondary outcomes:
measure: Underlying allergic disease
timeFrame: on the day of survey (day 1)
measure: Family history of allergic disease
timeFrame: on the day of survey (day 1)
measure: Occupation
timeFrame: on the day of survey (day 1)
measure: Duration of occupation
timeFrame: on the day of survey (day 1)
measure: Contact animal
timeFrame: on the day of survey (day 1)
measure: Contact time
timeFrame: on the day of survey (day 1)
measure: Causal animal
timeFrame: on the day of survey (day 1)
measure: Contact situation
timeFrame: on the day of survey (day 1)
measure: Allergic symptom during contacting animal
timeFrame: on the day of survey (day 1)
Other outcomes:
Locations:
city: Incheon
country: Korea, Republic of
facility: Gachon University Gil Medical Center
Study officials:
affiliation: Gachon University Gil Medical Center
name: Sang Min Lee, MD, PhD
role: PRINCIPAL_INVESTIGATOR
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