Clinical trial NCT01533064: Response of Psychiatric Outpatients to the Great East Japan Earthquake
Official title: Response of Psychiatric Outpatients to the Great East Japan Earthquake
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Mood Disorders
Lead sponsor: Ashikaga Red Cross Hospital
Sponsor class: OTHER
First posted: 2012-02-15
Enrollment: 328
Sex: ALL
Minimum age (years): 11
Maximum age (years): 90
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: a total of 328 psychiatric outpatients of Ashikaga Red Cross Hospital

Brief summary: Objective: Reports have described how hospitalized psychiatric patients respond to disasters; however, few reports have described the response to disaster among psychiatric outpatients, who have relatively mild disease in comparison with hospitalized, severely ill psychiatric patients. Here the investigators have analyzed the response to disaster among this under-studied population.

Method: The Great East Japan Earthquake on March 11, 2011, was a catastrophic disaster. The investigators studied psychiatric change among a population of psychiatric outpatients in Tochigi prefecture, located \~160 km (\~100 miles) southeast of the Fukushima nuclear power plant, in an area that suffered moderate damage from the earthquake. A total of 328 psychiatric outpatients were enrolled and were grouped into the diagnostic categories F2 (schizophrenic, schizotypal, and delusional disorders), F3 (affective disorders), and F4 (neurotic, stress-related, and somatoform disorders). All diagnoses were made using International Classification of Diseases (ICD) 10 criteria. Changes in symptoms were measured as a change in psychotropic medication after the disaster.

Detailed description: Patient progress was determined by whether a change in medication was needed. We focused on psychotropic drug use, including the use of neuroleptics, antidepressants, and benzodiazepines, directly after the disaster on March 11, 2011. Changes in other psychotropic drugs that are prescribed less frequently, such as lithium or anticonvulsants, were not considered in this study. Changes in symptoms that did not require a need to change psychotropic medications were not considered as part of a patient's progress. Physicians rated the relationship between each change in psychotropic drug and the disaster as direct, indirect, or not relevant. Only when three physicians rated the relationship as direct did we consider the change in a patient's progress to be due to the earthquake. Worsening or improvement of symptoms was defined as a change in psychotropic medications as a result of the deterioration or improvement, respectively, of symptoms. The data were stratified by disease category and sex and analyzed using chi-square tests.

Eligibility criteria: Inclusion Criteria:

* Outpatients of Ashikaga Red Cross Hospital before the Great East Japan Earthquake on March 11, 2011 who are classified as F2 (schizophrenic, schizotypal, and delusional disorders), F3 (affective disorders), or F4 (neurotic, stress-related, and somatoform disorders), using International Classification of Diseases (ICD) 10 diagnostic criteria

Exclusion Criteria:

* Outpatients who did not consult with our hospital in the 2 months after the earthquake were excluded.

Primary outcomes:
measure: Patient progress determined by whether a change in medication was needed.
timeFrame: 2 months after the disaster
Secondary outcomes:
Other outcomes:
Locations:
city: Ashikaga
country: Japan
facility: Ashikaga Red Cross Hospital
state: Tochigi-Prefecture
city: Ashikaga
country: Japan
facility: Ashikaga Red Cross Hospital
state: Tochigi
Study officials:
affiliation: Ashikaga Red Cross Hospital
name: Michitaka Funayama, M.D.
role: PRINCIPAL_INVESTIGATOR
References: