Clinical trial NCT03503903: Efficacy of Wet Cupping on Reactive Oxygen Species and Antioxidants
Official title: Efficacy of Wet Cupping on Reactive Oxygen Species and Antioxidant Capacity:A Self-controlled Interventional Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: Wet cupping therapy
antioxidant capacity
Lead sponsor: Karabuk University
Sponsor class: OTHER
First posted: 2018-04-20
Enrollment: 24
Sex: MALE
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study evaluates the efficacy of Wet cupping Therapy on oxidative stress and antioxidant capacity of the body.The healthy volunteers will receive wet cupping application and their initial venous blood samples and samples after the treatment will be evaluated for oxidative stress.

Detailed description: Among the healthy individuals who applied for Wet Cupping Therapy (WCT) to Traditional and Complementary Therapies center in Karabuk Medical Faculty Education and Research Hospital for general wellbeing 24 volunteers were enrolled in the study. They will receive three concecutive WCT application in one month interval.Their venous blood samples obtained initially and after the completion of the three concecutive applications, will be evaluted in terms of Reactive Oxygen species and Antioxidant capacity.Additionally samples from the cupping blood during the first and the third WCT application will also be obtained and evaluated.

Eligibility criteria: Inclusion Criteria:

Healthy male adults

Must apply Traditional and complemantary medicine center for general well being.

Exclusion Criteria:

Any chronic disorder

Antiagregant drug usage

Bleeding disorders

-

Primary outcomes:
measure: TAS
timeFrame: 7 days
measure: TOS
timeFrame: 7 days
Secondary outcomes:
measure: SOD
timeFrame: 7 days
measure: CAT
timeFrame: 7 days
Other outcomes:
Locations:
city: Karabük
country: Turkey
facility: Karabuk University Karabuk Research and Education hospital
state: Karabuk
Study officials:
affiliation: Karabuk University
name: SULEYMAN ERSOY
role: PRINCIPAL_INVESTIGATOR
References:
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citation: S. El Sayed, H. Mahmoud, M. Nabo, Methods of wet cupping therapy (Al-Hijamah): in light of modern medicine and prophetic medicine, Alternative & Integrative Medicine (2013) 1-16.
citation: Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol. 1997 Mar;82(2):291-5. doi: 10.1113/expphysiol.1997.sp004024.
citation: Lin MT, Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature. 2006 Oct 19;443(7113):787-95. doi: 10.1038/nature05292.
citation: Ersoy S, Benli AR. Continue or stop applying wet cupping therapy (al-hijamah) in migraine headache:A randomized controlled trial. Complement Ther Clin Pract. 2020 Feb;38:101065. doi: 10.1016/j.ctcp.2019.101065. Epub 2019 Oct 18.