Clinical trial NCT05546164: Strength and Dexterity of Less Affected Hand of Hemiparetic Cerebral Palsy Children
Official title: Strength and Dexterity of Less Affected Hand of Hemiparetic Cerebral Palsy Children: A Comparison Study With Normal Peers
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cerebral Palsy
Keywords: Cerebral Palsy
Unilateral cerebral palsy
grip strength
pinch strength
upper limb dexterity
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2022-09-19
Enrollment: 120
Sex: ALL
Minimum age (years): 6
Maximum age (years): 10
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This study will include 120 children of both gender with age from 6 years to 10 years

Brief summary: The contralateral hand deficits are often masked by the complex clinical presentation of the more affected hand in children with spastic hemiparesis. Thus, intervention targeting the contralateral hand is not often a component of the child's rehabilitation plan of care. The presence of bilateral hand deficits, even if subtle in the contralateral hand, may limit the transfer of unimanual gains following rehabilitation to bimanual activities of daily living tasks. However, conservation of upper-limb function of the less-affected side is highly important for individuals with hemiparesis, because this side is often employed as a compensatory 'tool' in performing activities of daily living . Therefore, the current study will be conducted to determine and compare the motor abilities of the less affected hand of children with hemiparesis.

Detailed description: An impairment of the less affected hand of hemiparetic cerebral palsy children can be detrimental to the development of bimanual skills. It would be beneficial to identify and quantify the severity of any impairment of the less affected hand of hemiparetic cerebral palsy children. Hemiparetic cerebral palsy may present with substantial deficits in hand function, because bimanual activities involve the ability to use the affected and contralateral hands together for grasp and stabilization. Several authors have evaluated bimanual involvement in cerebral palsy but these studies have not compared the contralateral hand with norms. The less affected hand is widely regarded as "normal" or "unaffected" and is consequently rarely evaluated.

Several authors have reported incidental findings of subtle deficits in the less affected extremity, noted that hemiparetic children "also presented motor impairments in their non-paretic hand, especially in dexterity.

The purpose of this study is to assess the grip ,pinch strength and dexterity of less affected hand of hemiparetic cerebral palsy children and compare with dominant hand of normal peers

Eligibility criteria: Inclusion Criteria:

* Children will be recruited according to the following criteria:
* Age range between 6 and 10 years.
* Both sexes
* The degree of spasticity rang from grade 1 to 1+ according to Modified Ashworth scale (Appendix II).
* They can follow the order during the testing.

Exclusion Criteria:Children will be excluded from the study if they had any of the following criteria;

* Significant visual or auditory defect that may affect their performance.
* Previous orthopedic surgery for upper extremity.
* Injection with Botulinium toxin in the last 6 months.
* Structural deformities in any joint or bone of the upper limbs.
* Practicing any form of sports.

Primary outcomes:
measure: Hand grip strength
timeFrame: from October 2022 to September 2023
measure: Hand pinch strength
timeFrame: from October 2022 to September 2023
measure: upper limb dexterity
timeFrame: from October 2022 to September 2023
Secondary outcomes:
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Faculty of Physical Therapy, Cairo University
Study officials:
affiliation: Cairo University
name: Emam EL-Negamy, PhD
role: STUDY_CHAIR
affiliation: Cairo University
name: Amira Mahmoud, PhD
role: STUDY_DIRECTOR
References: