Clinical trial NCT04220164: Observation of Blood Lipid Outcomes in Lipid Clinic
Official title: Observation of Blood Lipid Outcomes in Patients Who Receive Treatment in Lipid Clinic of Taipei MacKay Memorial Hospital
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Dyslipidemias
Lead sponsor: Mackay Memorial Hospital
Sponsor class: OTHER
Collaborators: name: Amgen
First posted: 2020-01-07
Enrollment: 500
Sex: ALL
Minimum age (years): 20
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients who are ≥20 years, have abnormal lipid profiles, need lipid-lowering drugs according to 2017 Taiwan Lipid Guideline in Lipid Clinic of Taipei MacKay Memorial Hospital.

Brief summary: Taipei MacKay Memorial Hospital will establish a Lipid Clinic for hyperlipidemic patients. In this Lipid Clinic, the physician will discuss with each individual patient and set an individualized LDL goal according to current guideline and regulation of National Health Insurance Administration (NHIA). The aim of this study is to observe blood lipid outcomes in patients who receive treatment in Lipid Clinic of Taipei MacKay Memorial Hospital.

Detailed description: Hyperlipidemia is a major risk factor of atherosclerotic cardiovascular disease (ASCVD), and therefore it is beneficial to prevent the risk of ASCVD by controlling the prevalence of hyperlipidemia. According to CEPHEUS Pan-Asia survey, the rate of LDL goal attainment in hyperlipidemic patients of Taiwan was suboptimal, especially in high-risk patients. 2017 Taiwan lipid guideline for high-risk patients has been published and clearly defined the treatment goal of blood LDL-C for high-risk patients. Besides, Taipei MacKay Memorial Hospital will establish a Lipid Clinic for hyperlipidemic patients. In this Lipid Clinic, the physician will discuss with each individual patient and set an individualized LDL goal according to current guideline and regulation of National Health Insurance Administration (NHIA). The aim of this study is to observe blood lipid outcomes in patients who receive treatment in Lipid Clinic of Taipei MacKay Memorial Hospital.

Eligibility criteria: Inclusion Criteria:

* ≥20 years-old
* Abnormal lipid profiles according to 2017 Taiwan Lipid Guideline for High-risk Patients

Exclusion Criteria

* Reject to participate in this study
* Pregnant women
* Prisoner
* Illiteracy
* HIV patients
* Individuals who are mentally retarded, homeless, and handicapped

Primary outcomes:
measure: Lipid profile
timeFrame: 12 month
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Taiwan, Taipei, Mackay Memorial hospital
Study officials:
affiliation: Mackay Memorial Hospital
name: Chao-Feng Lin, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Li YH, Ueng KC, Jeng JS, Charng MJ, Lin TH, Chien KL, Wang CY, Chao TH, Liu PY, Su CH, Chien SC, Liou CW, Tang SC, Lee CC, Yu TY, Chen JW, Wu CC, Yeh HI; Writing Group of 2017 Taiwan Lipid Guidelines for High Risk Patients. 2017 Taiwan lipid guidelines for high risk patients. J Formos Med Assoc. 2017 Apr;116(4):217-248. doi: 10.1016/j.jfma.2016.11.013. Epub 2017 Feb 24.