Clinical trial NCT06559202: Inguinal and Axillary LN Size Distribution
Official title: Evaluation of Inguinal and Axillary Lymph Node Size Distribution for Safe Intralymphatic Injection
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Lymph Nodes
Keywords: lymph nodes
immunotherapy
intralymphatic immunotherapy
computed tomography
Lead sponsor: Gachon University Gil Medical Center
Sponsor class: OTHER
Collaborators: name: Dankook University
First posted: 2024-08-19
Enrollment: 133
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: subjects who underwent chest and abdominopelvic computed tomography on the same day for health screening purposes

Brief summary: Recently, intralymphatic allergen-specific immunotherapy (ILIT) showed promising treatment outcomes for allergic rhinoconjunctivitis. However, the normal size distribution of superficial lymph nodes (LNs) on the trunk that are potential target LNs for ILIT has not been evaluated.

The objective of this study is to investigate the distribution of LN size in inguinal and axillary area.

Detailed description: In this study, the long-axis diameters of the largest LNs in the inguinal and axillary areas were retrospectively measured in subjects who underwent chest and abdominopelvic computed tomography on the same day for health screening purposes from September 2022 to November 2022.

Eligibility criteria: Inclusion Criteria:

* subjects who underwent chest and abdominopelvic computed tomography on the same day for health screening purposes

Exclusion Criteria:

* Malignancy
* Follow-up less than 1-year

Primary outcomes:
measure: Inguinal LN size
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Axillary LN size
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
Secondary outcomes:
measure: Subjects with inguinal LN size ≥ 10mm
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Subjects with axillary LN size ≥ 10mm
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
Other outcomes:
measure: Correlation between inguinal and axillary LN sizes
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between inguinal LN size and age
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between axillary LN size and age
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between inguinal LN size and height
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between axillary LN size and height
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between inguinal LN size and BMI
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between axillary LN size and BMI
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between inguinal LN size and weight
timeFrame: On the day when chest and abdominopelvic CT was performed during the study period from 1st SEP 2022 to 30th NOV 2022
measure: Correlation between axillary LN size and weight
timeFrame: On the day when chest and abdominopelvic CT was during the study period from 1st SEP 2022 to 30th NOV 2022
Locations:
city: Incheon
country: Korea, Republic of
facility: Gachon University Gil Medical Center
Study officials:
affiliation: Gachon University Gil Medical Center
name: So Hyun Park, MD, PhD
role: STUDY_DIRECTOR
References: