Clinical trial NCT04969003: Reducing Transphobia Among Adolescents Through a Brief Video Intervention
Official title: Reducing Transphobia Among Adolescents Through a Brief Video Intervention
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Transgenderism
Depression
Lead sponsor: Yale University
Sponsor class: OTHER
First posted: 2021-07-20
Enrollment: 200
Sex: ALL
Minimum age (years): 14
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purposes of this new study are to test among adolescent viewers the utility of brief video-based interventions to:

1. reduce transphobia;
2. reduce depression-related stigma and increase likelihood of treatment-seeking; and
3. examine the role of viewer's sex (male / female / non-binary), race (Black vs non-Black), and sexual orientation (straight vs LGBQ) as independent factors on the outcomes of interest.

Detailed description: Intervention videos will each be of \~100-second duration and feature four underage professionals (ages 16) acting as simulated patients. All videos will focus on an empowered presenter with depression sharing their personal story regarding depression. They will describe how social supports from family, friends, and community, as well as professional help assisted them in overcoming symptoms of the illness, as well as how being transgender may have had an impact on it. The four actors will include two males (one trans, one cis) and tow females (one trans, one cis).

Assessments will occur at baseline and post-intervention, and will include:

1. Demographics (baseline only);
2. Primary outcome:

   a. Attitudes toward Transgender Men and Women (ATTMW) scale.
3. Secondary outcome:

   1. Transgender attitudes: feelings thermometer, modeled after Norton et al 2013.
   2. Depression-related stigma (Depression Stigma Scale \[DSS\]);and
   3. Help-seeking (General Help-Seeking Questionnaire \[GHSQ\]).

For each of study we intend to randomly assign \~1,000 individuals aged 14-18 as follows:

Randomized, in equal proportions, and stratified by sex and race, to view one of four \~100-second videos:

1. Transgender male;
2. Cis-gender male);
3. Transgender female;
4. Cis-gender female.

Eligibility criteria: Inclusion Criteria:

* English-speaking
* Living in the US
* Ages 14 - 18

Exclusion Criteria:

* None

Primary outcomes:
measure: Attitudes toward Transgender Men and Women (ATTMW) scale
timeFrame: Before / after viewing videos (within 10 minutes)
Secondary outcomes:
measure: Change in transgender attitudes: feelings thermometer
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in Depression-related stigma (Depression Stigma Scale [DSS]; Personal component only): TOTAL SCORE
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in Help-seeking (General Help-Seeking Questionnaire [GHSQ]; Emotional and Suicide components): MEAN SCORE
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in DSS Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Emotional Item 10
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in GHSQ Suicide Item 10
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 1
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 2
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 3
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 4
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 5
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 6
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 7
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in **ATTM** Item 11
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 8
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in ATTMW Item 9
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in **ATTM** Item 11
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in **ATTW** Item 11
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in **ATTM** Item 10
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in **ATTW** Item 10
timeFrame: Before / after viewing videos (within 10 minutes)
measure: Change in **ATTW** Item 12
timeFrame: Before / after viewing videos (within 10 minutes)
Other outcomes:
Locations:
city: New Haven
country: United States
facility: Yale Child Center
state: Connecticut
city: New Haven
country: United States
facility: Yale Child Study Center
state: Connecticut
Study officials:
References:
citation: Griffiths KM, Christensen H, Jorm AF, Evans K, Groves C. Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomised controlled trial. Br J Psychiatry. 2004 Oct;185:342-9. doi: 10.1192/bjp.185.4.342.
citation: Wilson CJ, Deane FP, Marshall KL, Dalley A. Adolescents' suicidal thinking and reluctance to consult general medical practitioners. J Youth Adolesc. 2010 Apr;39(4):343-56. doi: 10.1007/s10964-009-9436-6. Epub 2009 Jul 15.
citation: Norton AT, Herek GM. Heterosexuals' attitudes toward transgender people: findings from a national probability sample of US Adults. Sex Roles. 2013;68(11-12):738-753. doi:10.1007/s11199-011-0110-6
citation: Billard TJ. Attitudes Toward Transgender Men and Women: Development and Validation of a New Measure. Front Psychol. 2018 Apr 3;9:387. doi: 10.3389/fpsyg.2018.00387. eCollection 2018.
citation: Amsalem D, Halloran J, Penque B, Celentano J, Martin A. Effect of a Brief Social Contact Video on Transphobia and Depression-Related Stigma Among Adolescents: A Randomized Clinical Trial. JAMA Netw Open. 2022 Feb 1;5(2):e220376. doi: 10.1001/jamanetworkopen.2022.0376.