Clinical trial NCT05279404: Effect of Electroacupuncture at Neiguan on Cardiac and Gastric Function
Official title: Effect of Electroacupuncture at Neiguan on Cardiac and Gastric Function
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Cardiac and Gastric Function
Lead sponsor: China Medical University Hospital
Sponsor class: OTHER
First posted: 2022-03-15
Enrollment: 72
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: Acupuncture have been used in clinical treatment of diseases for at least 3,000 years, and the efficacy of acupuncture has been recognized by countries all over the world. However, most of the selected points for acupuncture treatment of diseases are based on ancient books or inheritance of experience. For example, the " Shizong Acupoint Ballad " of acupuncture records: "Neiguan (PC6) care about the chest and stomach", that is, acupuncture Neiguan can be used to treat chest, heart and stomach diseases. However, there is no scientific evidence to verify this argument so far that the Shizong Acupoint Ballad mentions "Neiguan care for the chest and stomach", and that means that Neiguan acupoint can treat the diseases of cardiovascular system and gastrointestinal system. The purpose is to verify the argument of "Neiguan care about the chest and stomach", and design a clinical trial of the Neiguan and Jianshi (PC5) on both sides of the electroacupuncture (EA) to simultaneously evaluate the heart and stomach functions. We designed a crossover test; total 72 subjects randomly equally divide the into a sham group (sham electroacupuncture) and an EA group \[2Hz EA (PC6 is cathode) and PC5 is anode\]. At least one week of washing time, then the EA group changed to a sham group and the sham group changed to an EA group.

In this study, it is expected that the EA at PC6 and PC5 will affect the heart function and the function of the stomach at the same time, verifying the argument that "the PC6 care of the chest and stomach" recorded in the Shizong Acupoint Ballad.


Eligibility criteria: Inclusion Criteria:

* (1) Normal and healthy participants
* (2) Male or female
* (3) The age range is 20 to 40 years old.
* (4) Those who participates and signs informed consent after explaining the research purpose and process in detail.

Exclusion Criteria:

* (1) Those with serious diseases, such as heart failure, chronic failure or cancer patients, etc.
* (2) Those who are allergic to stainless steel needles for acupuncture.
* (3) Pregnant or breastfeeding
* (4) Those who are taking medicines or food such as coffee, etc. that will affect heart function such as heart rate, or gastric peristalsis.
* (5) Unable to cooperate with researchers such as mental instability.
* (6) Those who do not sign the consent form.

Primary outcomes:
measure: Cardiac Function
timeFrame: thirty minutes.
measure: Cardiac Function
timeFrame: thirty minutes.
measure: Cardiac Function
timeFrame: thirty minutes.
measure: Cardiac Function
timeFrame: thirty minutes.
measure: Cardiac Function
timeFrame: thirty minutes.
measure: Cardiac Function
timeFrame: thirty minutes.
measure: Gastric Function
timeFrame: thirty minutes.
measure: Gastric Function
timeFrame: thirty minutes.
measure: Gastric Function
timeFrame: thirty minutes.
measure: Gastric Function
timeFrame: thirty minutes.
measure: Gastric Function
timeFrame: thirty minutes.
measure: Gastric Function
timeFrame: thirty minutes.
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References: