Clinical trial NCT01735981: The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease
Official title: The Effect of Video Game Biofeedback Modulated Exercise (ViBE)on Dynamic Balance and Gait in Individuals With Huntington's Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Huntington's Disease
Keywords: Huntington's Disease
gait
exercise
balance
video game
Lead sponsor: Ohio State University
Sponsor class: OTHER
First posted: 2012-11-28
Enrollment: 24
Sex: ALL
Minimum age (years): 18
Maximum age (years): 79
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Participants completed one arm of the study and then crossed over into the other arm of the study
Primary purpose: TREATMENT

Brief summary: To examine the benefits of using a video-game, Dance, Dance, Revolution, as an exercise modality to improve gait and balance in individuals with Huntington's disease.

Detailed description: The primary purpose of this study was to determine the effectiveness of a therapist-guided Video-game Biofeedback Modulated Exercise (ViBE) program administered via Dance Dance Revolution to improve dynamic balance, gait and mobility in individuals with Huntington's Disease. Secondary aims were to explore whether the ViBE intervention would improve quality of life, fall risk, and neuropsychological functions. The investigators hypothesized that the video-game program would lead to greater improvements in walking, dynamic balance, quality of life, fall risk, and neuropsychological function than a control handheld video game program. Since motivation is essential to the long-term maintenance of an exercise program the investigators were also interested in finding out how successful people with Huntington's Disease were at playing Dance Dance Revolution, what their perceptions were of playing the game, and whether they thought that it was beneficial

Eligibility criteria: Inclusion Criteria:

* adults 18 - 79 with a diagnosis of Huntington's disease

Exclusion Criteria:

* cannot walk 10 feet without assistance, any other neurologic condition

Primary outcomes:
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
measure: Gait Parameters
timeFrame: 6 weeks
Secondary outcomes:
measure: Tinetti Mobility Test
timeFrame: 6 weeks
measure: Four Square Step Test
timeFrame: 6 weeks
measure: Activities-Specific Balance Confidence Scale
timeFrame: 6 weeks
measure: World Health Organization Quality of Life
timeFrame: post intervention and post hand-held game, each lasts 6 weeks
Other outcomes:
Locations:
city: Columbus
country: United States
facility: The Ohio State University Atwell Hall
state: Ohio
Study officials:
affiliation: Ohio State University
name: Deb Kegelmeyer, DPT, MS
role: PRINCIPAL_INVESTIGATOR
affiliation: Ohio State University
name: Anne Kloos, PT, PhD
role: PRINCIPAL_INVESTIGATOR
References: