Clinical trial NCT06110104: Effect of Retrowalking Program Versus Whole Body Vibration in Patients With Chronic Knee Osteoarthritis
Official title: Effect of Retrowalking Program Versus Whole Body Vibration on Quadriceps Muscle Torque in Patients With Chronic Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: quadriceps torque,quadriceps endurance,balance,funcitional disability.
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2023-10-31
Enrollment: 45
Sex: ALL
Minimum age (years): 40
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: interventions; the first intervention: The Routine physiotherapy program comprises a combination of closed kinetic chain and open kinetic chain exercises, including straight leg raising, isometric quadriceps, isometric hip adduction, terminal knee extension, semi-squat, and leg press for 6 weeks.

the other intervention : Retro-walking program is about 10 min of supervised retro walking training 3 days a week for 6 weeks at their comfortable walking speed . The participants will be instructed to gradually increase their walking time up to 30 min over the 6-week period.

the last intervention is whole body vibration is 3 days per week for 6 weeks. During the training, the participants will perform static squat training barefoot on the platform with bent knees (30° and 60°). The distance between the feet was consistent with the shoulders. the duration time, sets and total time will be increased progressively over the 6-week.
Primary purpose: TREATMENT

Brief summary: Osteoarthritis is one of the most common degenerative joint disease that affects approximately more than 300 million people worldwide

Detailed description: this study compare the efficacy of Retro-walking program and whole body vibration on quadriceps muscle torque,endurance, Balance and knee functional disability in patients with chronic unilateral knee Osteoarthritis . it has three groups. first group recieves The Routine physiotherapy program comprises a combination of closed kinetic chain and open kinetic chain exercises cause the least intraarticular inflammation, bone destruction, and pressure over the joint. the seconed group recieves routine physiotherapy and Retro-walking which is considered a safe Closed Kinematic Chain exercise since the compressive forces at the patello-femoral joint are reduced. it include improvement in muscle activation pattern, Reduction in adductor moment at knee during stance phase of gait and augmented stretch of hamstring muscle groups during the stride; all of these may have helped in reducing disability thus leading to improved function.It reduces quadriceps eccentric function, while the isometric and concentric quadriceps strength are preserved improved pain relief and aerobic fitness level, without aggravating symptoms following walking programs in patients with knee OA. the third group recieves routine physiotherapy program and Whole-body vibration training which is now a day's got its wider importance, especially in clinical cases. It has a role in maintaining balance, proprioception, blood circulation, and hormone level that enhances the effect on the neuromuscular system . it is a new type of exercise therapy, which mainly improves muscle coordination to optimize joint function .it is performed as a neuromuscular modality in muscle strength training . As it is safe, effective and potentially feasible treatment, WBV training has also been proposed for several musculoskeletal system diseases.

the study ethical committee number is NO:P.T.REC/012/004280. the total sample size are 45 (for 3 groups), 45 patients (15 patients per group).

Eligibility criteria: Inclusion Criteria:

* 1.Subjects are required to have a radiograph of the knee joints within 2 weeks of testing.

  2.Weight-bearing, fixed flexion radiographs of the knee were taken in the AP views .

  3.Radiographic evidence of knee OA.according to Kellgren and Lawrence classification scale (gradeIII) as 0,Normal and 4,Sever.

  4.Particepants age are 40-55 . 5.Knee pain for at least 3 month , with pain presenting at least 3 days a week during last month.

  6.functional limitations (patients with pain \&stiffnes), The Arabic version of the western womac (ArWOMAC) scores (average 37) 7.ability to ambulate independently for at least 10 meters. 8.Ability to follow simple structures.

Exclusion Criteria:

* 1.(BMI) more ≥ 30. 2.History of knee surgery to knee within past 3 months 3.A systemic arthritic condition. 4.Any other muscular, joint or neurological condition affecting lower limb function.

  5.Physical therapy or an intra-articular injection in the knee within the past 3 months.

  6.Change in pain medications in the previous month. 7.Healthy participants, impairment conditions unrelated to gait conditions such as cardio- and respiratory-related diseases, people with lower limb amputations, and lower prosthetic limbs.

Primary outcomes:
measure: quadriceps torque
timeFrame: 6 weeks
measure: quadriceps endurance
timeFrame: 6 weeks
measure: balance
timeFrame: 6 weeks
measure: knee functional disability
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Faculty of Physical Therapy
Study officials:
affiliation: Cairo University
name: manal mo ismail, PHD
role: STUDY_CHAIR
affiliation: Cairo University
name: sara mo samir, MSc
role: STUDY_DIRECTOR
affiliation: faculty of physical therapy cairouniversity
name: Ahmed om abd el naem, MSc
role: STUDY_DIRECTOR
affiliation: faculty of physical therapy
name: marwa ga amr, BSc
role: PRINCIPAL_INVESTIGATOR
References: