Clinical trial NCT06485479: Effective Ads for Quitting Smoking
Official title: Identifying Effective Ads to Encourage Quitting Smoking Among People Who Smoke Menthol Cigarettes
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Smoking Behaviors
Lead sponsor: UNC Lineberger Comprehensive Cancer Center
Sponsor class: OTHER
Collaborators: name: Food and Drug Administration (FDA)
name: National Institute on Drug Abuse (NIDA)
First posted: 2024-07-03
Enrollment: 1236
Sex: ALL
Minimum age (years): 21
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The main purpose of this trial is to identify effective quit smoking ads for people who smoke menthol cigarettes. Investigators will conduct an online randomized trial with a nationally representative sample of \~1,400 US adults (ages 21+) who smoke menthol cigarettes.

Detailed description: This trial will evaluate the effectiveness of efficacy-based quit smoking ads in a 5 (theme) x 6 (ad) mixed factorial randomized design.

Recruitment: A survey company will recruit \~1,400 participants. Participants will complete a screener to confirm that they are US adults (ages 21+), currently smoke menthol cigarettes, and are able to read and speak English. A portion of the sample will be nationally representative, and a portion will be a convenience sample.

Informed Consent: The consent form will appear on the first page of the survey. Participants will provide their consent to be in the trial by clicking on a button that forwards to the next page of the survey.

Randomization: After consent, the survey software will randomize participants to 1 of 5 themes between-subjects. The design will include 3 intervention ad themes about quitting smoking (self-efficacy ads, response efficacy ads, or motivation ads) and 2 control ad themes about neutral non-smoking related topics (reading or password safety).

Each participant will view 6 ads on their assigned theme, presented in a random order.

Assessment: Participants will complete a \~15 minute online survey one time.

Eligibility criteria: This national trial is not open to enrollment from the general public. Participation is restricted to individuals who meet the following inclusion and exclusion criteria:

Inclusion Criteria

* Currently smoke menthol cigarettes
* Be a member of the AmeriSpeak online survey panel or their convenience sample
* Live in the US
* Be age 21 years or older
* Read and speak English

Exclusion Criteria

* Not currently smoke menthol cigarettes
* Not be a member of the AmeriSpeak online survey panel or their convenience sample
* Not live in the US
* Be younger than age 21 years
* Not be able to read and speak English

Primary outcomes:
measure: Perceived message effectiveness for motivation
timeFrame: During exposure to the ads, assessed during one-time online 15-minute survey.
Secondary outcomes:
measure: Perceived message effectiveness for response efficacy
timeFrame: During exposure to the ads, assessed during one-time online 15-minute survey.
measure: Perceived message effectiveness for self-efficacy
timeFrame: During exposure to the ads, assessed during one-time online 15-minute survey.
measure: Intentions to quit smoking
timeFrame: After exposure to the ads, assessed during one-time online 15-minute survey.
measure: Response efficacy
timeFrame: After exposure to the ads, assessed during one-time online 15-minute survey.
measure: Self-efficacy
timeFrame: After exposure to the ads, assessed during one-time online 15-minute survey.
Other outcomes:
Locations:
city: Chapel Hill
country: United States
facility: University of North Carolina
state: North Carolina
Study officials:
affiliation: University of North Carolina, Chapel Hill
name: Noel Brewer, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: University of North Carolina, Chapel Hill
name: Marissa G Hall, PhD
role: PRINCIPAL_INVESTIGATOR
References: