Clinical trial NCT05886179: COVID-19 IN CHILDREN IN NIGER, 2020
Official title: Factors Associated With COVID-19 in Children Aged 0-15 Years in Niger, 2020
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: to Contribute to a Better Control of COVID-19 in Children in Niger
Keywords: factors, COVID-19, children, database, Niger
Lead sponsor: Centre de Recherche Médicale et Sanitaire
Sponsor class: OTHER
First posted: 2023-06-02
Enrollment: 572
Sex: ALL
Minimum age (years): 0
Maximum age (years): 15
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This was an analytical cross-sectional study with retrospective collection of epidemiological surveillance data on COVID-19 in Niger. The study period spanned six (6) months from February 25 to August 28, 2020. Children aged 0-15 years suspected of having COVID-19 whose data were in the DSRE database were included. We used the data extraction form that served as a secondary database containing only our variables of interest.

Brief summary: On January 30, 2020, the WHO declared COVID-19 a global health emergency. Children were affected with less severe forms. Niger had implemented measures in a context where children are a source of contamination. The objective was to determine the factors associated with COVID-19 in children in Niger from February to August 2020 through an analysis of the national database.

Detailed description: We conducted an analytical cross-sectional study including all COVID-19 suspects in the database. We used Excel and Epi Info 7.2.4. software for data extraction and analysis. Frequencies and proportions were calculated, we estimated in a logistic regression the OR of association with their 95% confidence interval, the factors associated with COVID-19 at the threshold of p\<0.05.

Results: Of 572 notified suspected COVID-19 cases in children aged 0-15 years, 11.36% were positive. The median age of infected children was 10 years \[IQR: 5- 13 years\]. The sex ratio of males to females was 2.1. Children aged 11-15 years were 49.2%, 61.5% resided in Niamey, 4.6% had comorbidities. The notion of travel was 12.3% and 40% had a notion of contact, 24.4% had a fever, 23.2% had a cough, 18% were hospitalized and the case fatality was 1.5%. In etiological analysis, the factors associated with COVID-19 were sex ORa= 0.51 \[0.28-0.93\] p=0.028, the presence of symptoms ORa= 2.29 \[1.23-4.25\] p=0.008 and the notion of contact ORa= 0.32 \[0.13-0.77\] p=0.011.

exposed children were sensitive to COVID-19, all age groups were affected with a male predominance. We recommend barrier measures adapted to young people, early detection and management of infected children.

Eligibility criteria: Inclusion Criteria:

* Children aged 0-15 years suspected of having COVID-19 whose data were in the DSRE database were included

Exclusion Criteria:

* Children whose data is not complete

Primary outcomes:
measure: data base analysis
timeFrame: May 2021
Secondary outcomes:
Other outcomes:
Locations:
city: Niamey
country: Niger
facility: IDE AMADOU Habibatou
Study officials:
References: