Clinical trial NCT05799001: Dance Workshop for Institutionalized Seniors With Behavioral and Psychological Symptoms of Dementia
Official title: Dance Workshop for Institutionalized Seniors With Behavioral and Psychological Symptoms of Dementia
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Dementia
Lead sponsor: Centre Hospitalier Emile Roux
Sponsor class: OTHER
First posted: 2023-04-05
Enrollment: 180
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: It is estimated that the prevalence of dementia in France is 5% for people over 65 years of age and that this increases to 18% for people over 75 years of age. Behavioral disorders are frequent in patients with dementia and are the main cause of institutionalization, representing up to 50% of cases. Dementia syndromes can be translated into behavioral and psychological symptoms of dementia (BPSD), which are defined as perceptual, mood or behavioral disorders. To date, there is no cure for dementia, but certain measures can be taken to reduce symptoms. The HAS suggests that physical exercise would reduce BPSD and could improve the ability to perform activities of daily living or slow down the cognitive decline of this type of patient. Indeed, several articles have highlighted the benefits of physical activity in demented patients. A meta-analysis has shown a significant decrease in BPSD via the Neuropsychiatric Inventory (NPI) score. Nevertheless, it is often observed that there is a difficulty in adhering to the program in very elderly population groups. Dance is a complete physical activity that integrates physical, cognitive and social elements. A meta-analysis has shown that dance has a significant effect on global cognition but also on neuroplasticity and physical functioning in patients with mental disorders. The music component of dance also has an effect on the behavioral problems of demented patients, stimulating language ability and social and emotional function.

However, at present, no study of good methodological quality has been able to demonstrate the effectiveness of dance-based physical activity for the treatment of dementia symptoms. As a result of these findings, the APAISE project was developed and should help slow the onset of BPSD in patients with dementia.


Eligibility criteria: Inclusion Criteria:

1. Institutionalized patient (male or female) over 65 years of age ;
2. Patient with behavioral problems, as measured by an NPI-ES \> 3 on any item and an NPI-ES impact scale \> 2 ;
3. Patient able to mobilize the upper body at a minimum (arms, trunk, head);
4. Medication (antipsychotics, antidepressants, anxiolytics and related hypnotics) without major modification for at least 30 days prior to inclusion after medical advice;
5. Possibility of including patients under guardianship or curatorship;
6. Patient affiliated to a social security plan;
7. Obtaining consent from the patient or legal representative.

   Exclusion Criteria:
8. Inability of the patient to follow the sessions (e.g., major visual/auditory disabilities), difficult follow-up, or any other reason at the discretion of the investigator;
9. Inability of the health care team to complete the NPI-ES questionnaire for the patient;
10. Patient has a concurrent psychiatric disorder (e.g., bipolar disorder, schizophrenia, or other).

Primary outcomes:
measure: Compare the effectiveness of adding biweekly dance class for 4 months on behavioral and psychological symptoms of dementia in institutionalized older adults compared to usual care alone.
timeFrame: 4 months
Secondary outcomes:
Other outcomes:
Locations:
city: Craponne-sur-Arzon
country: France
facility: Centre Hospitalier Pays Craponne
Study officials:
References: