Clinical trial NCT02314338: The Short Physical Performance Battery in Chronic Obstructive Pulmonary Disease (COPD)
Official title: The Short Physical Performance Battery in COPD - Possible Impact of a Pulmonary Rehabilitation Program and Relationships to Other Physical Performance Measures, Symptoms, and Quality of Life.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Lead sponsor: LHL Helse
Sponsor class: OTHER
Collaborators: name: Lovisenberg Diakonale Hospital
name: Karolinska Institutet
First posted: 2014-12-11
Enrollment: 50
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Patients with COPD often have limitations to physical performance. There are several tests for evaluating physical performance, unfortunately many of them can be time consuming and require specialized equipment an substantial space. Short physical performance battery is a simple test that requires little resources and can be performed both at institutions and in the homes of patients. SPPB has high predictive abilities in identifying older adults at greater risk for mortality, nursing home admission, hospitalization, and incidence of disability. The investigators would like to evaluate possible changes in the SPPB score after a 4-week rehabilitation program. The investigators would also like to look at possible relationships between the SPPB and other physical performance measures, dyspnea, anxiety, depression, fatigue, and health related quality of life.


Eligibility criteria: Inclusion Criteria:

* Patients with all stages of COPD
* Decision making capacity to provide informed written consent
* Ability to understand and complete the questionnaires

Exclusion Criteria:

* Exacerbation within the last four weeks
* Co-morbidities that limits the patient's physical performance more than COPD
* Any patient whom is deemed unsafe to exercise
* Patients tested on treadmill protocol 4 (i.e. Glittre testing protocol)

Primary outcomes:
measure: Short physical performance battery (SPPB)
timeFrame: Pre and posttest with 4 weeks in between
Secondary outcomes:
measure: Lung function
timeFrame: 4 weeks
measure: 6-minute walk test (6MWT)
timeFrame: 4 weeks
measure: Borg category ratio-10 scale (Borg CR-10 scale)
timeFrame: 4 weeks
measure: Peripheral oxygenation level
timeFrame: 4 weeks
measure: Bilateral leg press 1 repetition Maximum (RM)
timeFrame: 4 weeks
measure: Modified Medical Research Council Dyspnea Scale (MMRC)
timeFrame: 4 weeks
measure: COPD assessment test (CAT)
timeFrame: 4 weeks
measure: Hospital anxiety and depression scale (HADS)
timeFrame: 4 weeks
measure: Fatigue severity scale (FSS)
timeFrame: 4 weeks
Other outcomes:
Locations:
city: Hakadal
country: Norway
facility: LHL-klinikkene Glittre
Study officials:
affiliation: LHL-klinikkene Glittre
name: Anne Edvardsen, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Larsson P, Borge CR, Nygren-Bonnier M, Lerdal A, Edvardsen A. An evaluation of the short physical performance battery following pulmonary rehabilitation in patients with chronic obstructive pulmonary disease. BMC Res Notes. 2018 Jun 4;11(1):348. doi: 10.1186/s13104-018-3458-7.