Clinical trial NCT00677781: Impact of Microparticles on Postoperative Complications in Surgical Patients
Official title: The Impact of Microparticles on Inflammatory Responses During Visceral and Cardiac Surgery
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Neoplasm, Hepatic
Pancreatic Neoplasms
Colorectal Neoplasms
Lead sponsor: University of Bern
Sponsor class: OTHER
First posted: 2008-05-15
Enrollment: 108
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients undergoing cardiac or hepatobiliary or colorectal surgery. Setting: university hospital.

Brief summary: Microparticles are cellular fragments which are released actively or passively under conditions of inflammation and stress. The impact of surgical operations on quantity and quality of microparticles remains unknown. In this observatory study we investigate quantitative and qualitative aspects of microparticles during cardiac and abdominal operations.


Eligibility criteria: Inclusion Criteria:

* Patients undergoing cardiac or abdominal operations with a minimum expected operative time of 2 hours

Exclusion Criteria:

* Laparoscopic operations
* emergency operations

Primary outcomes:
measure: Postoperative morbidity
timeFrame: 30 days
Secondary outcomes:
measure: Hospital stay
timeFrame: 30 days
measure: Mortality
timeFrame: 30 days
Other outcomes:
Locations:
city: Bern
country: Switzerland
facility: Department of visceral and transplant surgery, Bern University Hospital
Study officials:
affiliation: Bern University Hospital
name: Guido Beldi, MD
role: PRINCIPAL_INVESTIGATOR
References:
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