Clinical trial NCT06240390: Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain
Official title: Study of the Effectiveness of Ultrasound-guided Percutaneous Neuromodulation Versus Pharmacological Treatment in Oncology Patients With Anterior Knee Pain
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Pain Cancer
Keywords: Cancer
Pain
Anterior Knee Pain
NMP
Lead sponsor: Universidad Europea de Canarias
Sponsor class: OTHER
First posted: 2024-02-05
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: the goal of this clinical trial is to compare in cancer patients:

Is ultrasound-guided percutaneous neuromodulation useful for Anterior Knee Pain relief in cancer patients?

Participants will receive treatments of ultrasound-guided percutaneous neuromodulation and pharmacological treatment Researchers will compare ultrasound-guided percutaneous neuromodulation versus pharmacological treatment to see if Anterior Knee Pain is reduced

Detailed description: Unhealthy lifestyles, an aging population and increased life expectancy increase the likelihood of cancer. Knee pain is one of the most common symptoms that cause functional incapacity, which requires the search and improvement of its assessment, prevention and treatment tools.

Physiotherapists are currently using ultrasound-guided Percutaneous Neuromodulation clinically. It is an easy process to perform, non-invasive, safe and economical.

Traditional therapies have been and will continue to be useful. The decrease in manufacturing costs of assessment tools such as ultrasound and neuromodulator treatment in recent years has made the acquisition of these equipment as intervention tools economical. This is because they have been shown to be useful for improving function and reducing pain.

Opioid analgesics are the main option for pain treatment in cancer patients, but their side effects and inadequate treatment lead to cheaper, quicker options with lower risk of addiction and/or side effects.

In order to improve these symptoms, it is essential to have an objective knowledge of the changes produced by neuromodulation and to be able to measure the variation of pain experienced by patients.

It has been demonstrated in recent years that assessment tools such as ultrasound and myotonometer are very useful, safe and non-invasive procedures, both have been consolidated as assessment tools that can evaluate changes and analyze the contractile properties of soft tissue quickly and safely. There are abundant literature on this subject.

Therefore, researchers suggest conducting research that improves and provides new data on the efficacy and effectiveness of treatment of ultrasound-guided percutaneous neuromodulation.

Eligibility criteria: Inclusion Criteria:

The proposed inclusion criteria for the study are as follows:

* Age between 18 and 65.
* Pain in the front of the knee.
* Taking drug therapy for lower-extremity pain.
* Diagnosis of painful pathology in the anterior aspect of the knee secondary oncologic.

Exclusion Criteria:

The exclusion criteria are:

* Traumatic history
* Have had any type of analgesic treatment in the last 4 weeks (clinical, physical or orthostatic)
* No need for drug treatment within the last 30 days of study initiation.

Primary outcomes:
measure: Numerical Pain Rating Scale (NPRS) Anterior Knee Pain changes
timeFrame: 12 weeks
measure: Victorian Institute of Sport Assessment-Patella (VISA-P)
timeFrame: 12 weeks
measure: The OKS (Oxford Knee Score) questionnaire for knee function.
timeFrame: 12 weeks
measure: The Lower Limb Functional Index (LLFI).
timeFrame: 12 weeks
measure: Borg's Rating Perceived Exertion (RPE) questionnaire for perceived fatigue.
timeFrame: 12 weeks
measure: Pressure pain threshold
timeFrame: 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Santa Cruz De Tenerife
country: Spain
facility: Centro RED Tenerife
Study officials:
affiliation: Universidad Europea de Canarias
name: Eduardo Martín, MsC
role: PRINCIPAL_INVESTIGATOR
References: