Clinical trial NCT05339503: This is the Comparison of Clinical Effectiveness of Hydrochloric Acid-pumice Compound and Sodium Hypochlorite-pumice Compound Used in Microabrasion Technique for the Treatment of Dental Fluorosis. Change in Tooth Shade Was Checked Before and After the Procedure.
Official title: Comparison of Clinical Effectiveness of Hydrochloric Acid and Sodium Hypochlorite Used in Microabrasion Technique for the Treatment of Dental Fluorosis.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dental Fluoroses
Keywords: Hydrochloric Acid
Sodium Hypochlorite
Dental Fluorosis
Microabrasion Technique
Lead sponsor: Fatima Jinnah Dental College
Sponsor class: OTHER
First posted: 2022-04-21
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: To compare the clinical effectiveness of hydrochloric acid-pumice compound and sodium hypochlorite-pumice compound in treating dental fluorosis using microabrasion technique.

Detailed description: A Randomized Clinical Trial was taken Fatima Jinnah Dental College Hospital, Karachi, from 1st November 2019 To 30th April 2020. Total 30 teeth in each group were included. Preoperatively shade was checked. The mixture was applied 10 times or more during the same session. Total treatment time was around 30 minutes. Every patient received entire microabrasion treatment. At the end of the treatment, neutral sodium fluoride gel was applied. Then changes in shade were checked. Descriptive statistics were calculated.

Eligibility criteria: Inclusion Criteria:

* Patients aged 18-40 years .
* Permanent dentition assessed on clinical examination.
* Have at least four maxillary incisors with scores of 4 to 5, according to the Dean's Fluorosis Index.
* Have no caries or restoration on the teeth to be treated assessed clinically.

Exclusion Criteria:

* Poor oral dental and general health assessed on clinical examination.
* History of Smoking and any form of tobacco.
* Patients with periodontal disease assessed on clinical examination.
* Caries on anterior teeth assessed on clinical examination.
* Hypersensitive teeth assessed on clinical examination.

Primary outcomes:
measure: HYDROCHLORIC ACID PUMICE COMPOUND
timeFrame: 30 minutes
measure: SODIUM HYPOCHLORITE PUMICE COMPOUND
timeFrame: 30 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Karachi
country: Pakistan
facility: Fatima Jinnah Dental College
state: Sindh
Study officials:
affiliation: Fatima Jinnah Dental College
name: HAREEM A SATTAR, FCPS
role: PRINCIPAL_INVESTIGATOR
References:
citation: Nevarez-Rascon M, Molina-Frechero N, Adame E, Almeida E, Soto-Barreras U, Gaona E, Nevarez-Rascon A. Effectiveness of a microabrasion technique using 16% HCL with manual application on fluorotic teeth: A series of studies. World J Clin Cases. 2020 Feb 26;8(4):743-756. doi: 10.12998/wjcc.v8.i4.743.
citation: Sheoran N, Garg S, Damle SG, Dhindsa A, Opal S, Gupta S. Esthetic management of developmental enamel opacities in young permanent maxillary incisors with two microabrasion techniques--a split mouth study. J Esthet Restor Dent. 2014 Sep-Oct;26(5):345-52. doi: 10.1111/jerd.12096. Epub 2014 Mar 4.
citation: Gupta A, Dhingra R, Chaudhuri P, Gupta A. A comparison of various minimally invasive techniques for the removal of dental fluorosis stains in children. J Indian Soc Pedod Prev Dent. 2017 Jul-Sep;35(3):260-268. doi: 10.4103/JISPPD.JISPPD_138_16.