Clinical trial NCT05230303: Caffeine Supplementation, Resistance Training and Blood Antioxidant Status
Official title: Acute Effects of Caffeine Supplementation on Resistance Training Volume and Blood Antioxidant Status in Resitance Trained Men
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Caffeine
Keywords: sports performance, resistance training, nutrition, athlete
Lead sponsor: The Jerzy Kukuczka Academy of Physical Education in Katowice
Sponsor class: OTHER
First posted: 2022-02-08
Enrollment: 15
Sex: MALE
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to verify the effect of acute caffeine intake on resistance training volume and blood antioxidant status, in a randomised, double-blind, placebo-controlled crossover trial.

Detailed description: Caffeine is one of the most commonly consumed psychoactive substances in the world. Several previous studies confirmed that caffeine improves several aspects of exercise performance, including resistance training outcomes. Interestingly, caffeine and its catabolic products, theobromine and xanthine, exhibit antioxidant and prooxidant properties. Additionally, resistance training promotes the generation of reactive oxygen species, which are important for the cellular adaptation process.

Hovewer, to the best of our knowledge, there is no information as to how caffeine combined with resistance training affects blood antioxidant status. Therefore, the aim of this study was to examine acute effects of caffeine supplementation on resistance training volume and blood antioxidant status in resistance trained men.

Eligibility criteria: Inclusion Criteria:

* written consent to participate,
* medical permission by physician
* "resistance-trained," defined as having a minimum of two years of resistance training experience
* minimum of 2 workout sessions per week in the last 6 months

Exclusion Criteria:

* neuromuscular or musculoskeletal disorders
* current injury
* using any medications, dietary supplements or ergogenic aids which could potentially affect the study outcomes
* a positive smoking status
* potential allergy to caffeine

Primary outcomes:
measure: Change the levels of oxidative stress markers
timeFrame: Day 1, Day 2
measure: Changes in markers of muscle damage
timeFrame: Day 1, Day 2
measure: Changes in Inflammation markers
timeFrame: Day 1, Day 2
measure: Changes in markers of liver function
timeFrame: Day 1, Day 2
Secondary outcomes:
measure: Changes in resistance training volume
timeFrame: During caffeine and placebo treatment
measure: Changes in rate of perceived exertion after resistance training
timeFrame: Immediately after exercise protocol during caffeine and placebo treatment
measure: Changes in heart rate during resistance training
timeFrame: During caffeine and placebo treatment
measure: Changes in muscle soreness
timeFrame: prior to exercise, and 24, 48, 72, 96 and 120 hours post exercise.
Other outcomes:
Locations:
city: Katowice
country: Poland
facility: The Jerzy Kukuczka Academy of Physical Education
Study officials:
affiliation: The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland
name: Adam Zając, Profesor
role: STUDY_DIRECTOR
References: