Clinical trial NCT02999581: Effects of a Pre-Workout Dietary Supplement on Training Adaptations
Official title: Effects of a Pre-Workout Dietary Supplement on Training Adaptations in Resistance Trained Athletes
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dietary Modification
Lead sponsor: Texas A&M University
Sponsor class: OTHER
Collaborators: name: Nutrabolt
First posted: 2016-12-21
Enrollment: 122
Sex: MALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The purpose of this study is to examine the effects of a pre-workout dietary supplement during resistance training on training adaptations.

Detailed description: A number of nutritional strategies have been developed to optimize nutrient delivery prior to exercise. This includes providing carbohydrate and a number of ergogenic nutrients prior to, during and/or following exercise. As a result, a number of pre-workout supplements have been developed to increase energy availability, promote vasodilation and/or positively affect exercise capacity. The purpose of this study is to investigate the effects of ingesting a pre-workout dietary supplement during resistance training on training adaptations.

Eligibility criteria: Inclusion Criteria:

* you are an apparently healthy and recreationally active male between the ages of 18 and 40.
* you will need to have at least six months immediate prior history of resistance training on the bench press and leg press or squat.

Exclusion Criteria:

* you have a history of treatment for metabolic disease (i.e., diabetes), hypertension, hypotension, thyroid disease, arrhythmia and/or cardiovascular disease;
* you are currently using prescription medications;
* you have an intolerance to caffeine and/or other natural stimulants;
* you have a history of smoking;
* you drink excessively (i.e., 12 drinks per week or more);

Primary outcomes:
measure: Examine the effects of C4 supplementation during resistance training by assessing body water
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing body composition
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing macronutrient intake
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing 1 RM (repetition maximum) strength
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing anaerobic sprint capacity
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing muscle creatine levels
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing muscle carnosine levels
timeFrame: Eight weeks
measure: Examine the effects of C4 supplementation during resistance training by assessing cognitive function (i.e., Stroop Color and Word Test, Word Recall Test and Readiness to perform VAS)
timeFrame: Eight weeks
Secondary outcomes:
measure: Measure standard clinical chemistry panels in the blood to evaluate safety
timeFrame: Eight weeks
measure: Record side effects to evaluate safety
timeFrame: Eight weeks
measure: Measure heart rate to evaluate safety
timeFrame: Eight weeks
measure: Measure blood pressure to evaluate safety
timeFrame: Eight weeks
Other outcomes:
Locations:
Study officials:
References:
citation: Jung YP, Earnest CP, Koozehchian M, Cho M, Barringer N, Walker D, Rasmussen C, Greenwood M, Murano PS, Kreider RB. Effects of ingesting a pre-workout dietary supplement with and without synephrine for 8 weeks on training adaptations in resistance-trained males. J Int Soc Sports Nutr. 2017 Jan 3;14:1. doi: 10.1186/s12970-016-0158-3. eCollection 2017.