louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06283602: Oral Health in Children and Adolescents With Obesity and Normal Weight
Official title: Erosive Tooth Wear, Caries Experience and Periodontal Health in Children and Adolescents With Obesity and Normal Weight
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Pediatric Obesity
Pediatric Dentistry
Keywords: dental caries
periodontal health
children
obesity
erosive tooth wear
Lead sponsor: Kahramanmaras Sutcu Imam University
Sponsor class: OTHER
First posted: 2024-02-28
Enrollment: 82
Sex: ALL
Minimum age (years): 6
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.

82 participants aged 6-16 years were concluded in this cross-sectional study. The children/adolescents were classified according to the body mass index (BMI): NW (n=41) and OW (n=41). Caries experience was assessed by the International Caries Detection and Assessment System (ICDAS-II), decay, missing, filling teeth (dmft) for the primary teeth and (DMFT) for the permanent teeth, erosive tooth wear using Basic Erosive Wear Examination (BEWE), Plaque Index (PI) and Gingival Index (GI), Probing Depth (PD).

Detailed description: Also, the relationship between procalcitonin (PCT), C-reactive protein (CRP), parathormone (PTH), and 25(OH)D blood biochemistry and oral health was evaluated in obese children/adolescents.

Eligibility criteria: Inclusion Criteria: 6-16 years obesity children and adolescents

* 6-16 years healthy children and adolescents

Exclusion Criteria:

* Infection,
* diabetes, leukemia, asthma, bronchitis, cognitive neuromotor disorder, hormonal disease

Primary outcomes:
measure: the results of DMFT, plaque and gingival indies
timeFrame: 12 months
measure: the results of dmft, BEWE, ICDAS-II, probing dept
timeFrame: up to 12 months
measure: Comparison of demographic attributes between obese and normal weights
timeFrame: 12 months
Secondary outcomes:
measure: biochemical parameters of obese individuals
timeFrame: 11 months
measure: other biochemical parameters of obese individuals
timeFrame: up to 11 months
Other outcomes:
Locations:
city: Mersin
country: Turkey
facility: Aslı Soğukpınar Önsüren
Study officials:
References:
Clinical trial NCT01235702: Metro Atlanta Heart Disease Study - II (MAHDS II)
Official title: Multiple CVD Risk Reduction in Adult African-Americans: A Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: African Americans With Hypertension.
Keywords: high blood pressure, hypertension, African Americans, perceived stress
Lead sponsor: Morehouse School of Medicine
Sponsor class: OTHER
First posted: 2010-11-05
Enrollment: 210
Sex: ALL
Minimum age (years): 21
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: A 12-week treatment/control trial was implemented to assess the effects of a multi component lifestyle program on improvements in body mass index, weight, perceived stress and blood pressure in African American men and women who were at increased risk for cardiovascular disease. It was hypothesized that treatment group would experience significant improvements when compared to the control group.


Eligibility criteria: Inclusion Criteria: African American men and women aged \>21 with elevated blood pressure and excess body weight who resided in metro Atlanta, GA.

-

Exclusion Criteria: Individuals with normal blood pressure and body weight, as well as those residing outside of metro Atlanta, GA. Individuals with psychological conditions were also excluded.

-

Primary outcomes:
measure: blood pressure
timeFrame: 10/2002 - 11/2003
Secondary outcomes:
measure: body weight
timeFrame: 10/2002 - 11/2003
Other outcomes:
Locations:
city: Atlanta
country: United States
facility: Morehouse School of Medicine
state: Georgia
Study officials:
affiliation: Morehouse School of Medicine
name: Sharon K Davis, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04384302: Efficacy of Visual Training in Beach Tennis
Official title: Efficacy of Visual Training in Beach Tennis - a Pilot Study
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Visual Performance
Lead sponsor: Wrocław University of Science and Technology
Sponsor class: OTHER
First posted: 2020-05-12
Enrollment: 10
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: The proposed protocol is going to study the importance of wide spread of visual functions defined by but not limited to visual perception, visual function, visual exploration, involved in the performance of beach tennis. The investigators intend to examine the basic and important visual function that are required for the better performance in the field. The aim is to assess the efficacy of general training that uses the visual channel as the main one. The investigators suspects the improvement in the visual and motor skills after a predefined 8 weeks of visual training.


Eligibility criteria: Inclusion Criteria:

* experienced beach tennis player
* participants able and willing to participate in the study (including telemedicine supervision during the training phase)
* known and using full spectacles correction or its equivalent in contact lens correction

Exclusion Criteria:

* inability to give an informed consent
* any disease that causes visual opacity that unable to perform visual training
* participant unable to conduct full visual training course of the study

Primary outcomes:
measure: Optomechanical reaction time
timeFrame: 8 weeks
Secondary outcomes:
measure: Static visual acuity
timeFrame: 8 weeks
measure: Dynamic visual acuity
timeFrame: 8 weeks
measure: Overall performance during sparing match
timeFrame: 8 weeks
Other outcomes:
measure: The pace of macular fixation
timeFrame: 8 weeks
measure: Reading rate during the optokinetic task
timeFrame: 8 weeks
Locations:
city: Wrocław
country: Poland
facility: Department of Optics and Photonics
Study officials:
References:
Clinical trial NCT05625802: Erector Spinae Plane Block for Uncomplicated Renal Colic
Official title: Erector Spinae Plane Block for Uncomplicated Renal Colic
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE2
Conditions: Renal Colic
Kidney Stone
Keywords: erector spinae plane block
Emergency Department
ropivacaine
Lead sponsor: University of Michigan
Sponsor class: OTHER
First posted: 2022-11-23
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Single site two-stage open label phase 2 clinical trial with one treatment arm and one external control arm
Primary purpose: SUPPORTIVE_CARE

Brief summary: This research study is to determine how well the Erector Spinae Plane Block (ESPB) works for kidney stone pain and any possible side effects.


Eligibility criteria: Inclusion Criteria:

* Imaging confirmation of urolithiasis on the index encounter or prior encounter within 7 days
* Patient received one dose of parenteral pain medication in the emergency department (ED)

Exclusion Criteria:

* Pregnancy or breastfeeding
* Prisoner or incarcerated individual
* Therapeutic anticoagulation or coagulopathy.
* Active treatment for urinary tract infection (either acute infection or chronic therapy)
* Prior spinal surgery in the thoracic region
* Allergy to local anesthetic or prior local anesthetic
* Soft tissue infection overlying the injection site
* Positive for coronavirus
* Inability to communicate verbally or read/write in English
* Currently taking strong CYP1A2 inhibitor (fluvoxamine, amiodarone, fluoroquinolones, etc.)
* Glucose-6-phosphate dehydrogenase deficiency (G6PD)

Primary outcomes:
measure: Proportion of patients receiving a second parenteral pain medication in the Emergency Department (ED)
timeFrame: At ED discharge, approximately 1 day
Secondary outcomes:
measure: Change in pain
timeFrame: Baseline, 60 minutes following procedure
measure: Rate of admission to hospital
timeFrame: Up to 30-days
measure: Rate of 72-hour return to the Emergency Department (ED)
timeFrame: 3 days
Other outcomes:
Locations:
city: Ann Arbor
country: United States
facility: The University of Michigan
state: Michigan
Study officials:
affiliation: University of Michigan
name: Chris Fung
role: STUDY_CHAIR
References:
Clinical trial NCT00337402: Effects of Gastrostomy on Amyotrophic Lateral Sclerosis
Official title: Effects of Gastrostomy on Quality of Life and Survival in Patients With Amyotrophic Lateral Sclerosis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Amyotrophic Lateral Sclerosis
Keywords: Gastrostomy
Quality of life
Lead sponsor: University Hospital, Clermont-Ferrand
Sponsor class: OTHER
Collaborators: name: University Hospital, Angers
name: University Hospital, Bordeaux
name: University Hospital, Caen
name: University Hospital, Grenoble
name: University Hospital, Lille
name: University Hospital, Limoges
name: Neurological department of Lyon University Hospital
name: University Hospital, Marseille
name: University Hospital, Montpellier
name: Central Hospital, Nancy, France
name: Centre Hospitalier Universitaire de Nice
name: University Hospital, Paris
name: University Hospital, Strasbourg
name: University Hospital, Toulouse
name: University Hospital, Tours
First posted: 2006-06-16
Enrollment: 380
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: DEFINED_POPULATION
Time perspective: PROSPECTIVE

Brief summary: Results about effects of symptomatic treatment on QoL appears conflicting in ALS patients. Moreover no clear effects of gastrotomy have be shown on survival. Prospective study on effect of tube feeding, QoL and survival is performed in 17 teaching hospitals in France (observational study)

Detailed description: Following data have been recorded each three months: QoL (MOS-SF 36 and ALSAQ), bodily mass index, testing and ALS-FRS scale, functional respiratory measures, impedance analysis, and the time for tube feeding procedure, the conditions of the acceptance and side-effects of gastrotomy

Eligibility criteria: Inclusion Criteria:

* patients \> 18 years-old
* ALS certain or probable
* vital capacity (respiratory) \> 70 %
* under riluzole

Exclusion Criteria:

* ALS in family
* other conditions affected survival and QoL
* cognitive impairment

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Clermont-Ferrand
country: France
facility: Clermont-Ferrand University Hospital
Study officials:
affiliation: University Hospital, Clermont-Ferrand
name: Pierre Clavelou
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02343302: Prospective Trial Evaluating the Effect of Closed Suction Drainage Versus Straight Drainage After Distal Pancreatectomy
Official title: Prospective Trial Evaluating the Effect of Closed Suction Drainage Versus Straight Drainage After Distal Pancreatectomy
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Pancreatic Fistula
Keywords: Pancreatic Fistula
Lead sponsor: Johns Hopkins University
Sponsor class: OTHER
First posted: 2015-01-21
Enrollment: 2
Sex: ALL
Minimum age (years): 18
Maximum age (years): 100
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A very common complication following distal pancreatectomy is leakage from the pancreas, or what is called a pancreatic fistula. We hypothesize that operative drains which create suction may contribute to the development of leakage from the pancreas. This study evaluates the effect of using non-suctioning drains to prevent the development of this complication.

Detailed description: The most common complication following distal pancreatectomy is the developement of leakage from the remaining pancreas gland, which results in significant morbidity. Most surgeons leave dains at the time of surgery to prevent complications from pancreatic leakage. However, we hypothesize that drains which create continous negative pressure may contribute to the development of a pancreatic fistula. This study randomizes patients to suctioning versus non-suctioning drains. The primary endpoint is the development of pancreatic fistuale, as defined by the International Study Group of Pancreatic Surgery.

Eligibility criteria: Inclusion Criteria:

* Patients undergoing distal pancreatectomy at Johns Hopkins Hospital

Exclusion Criteria:

* Children \<18 years old, pregnant women, adults lacking capacity to consent, non-english speakers, and prisoners.

Primary outcomes:
measure: Post-operative Pancreatic Fistula
timeFrame: 90 days
Secondary outcomes:
measure: Morbidity
timeFrame: 90 days
Other outcomes:
Locations:
city: Baltimore
country: United States
facility: Johns Hopkins Hospital
state: Maryland
Study officials:
affiliation: Johns Hopkins University
name: Christopher L Wolfgang, MD PHD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01806402: Evaluation of OCT Measurements
Official title: Evaluation of the Precision and Accuracy of OCT Measurements in Retinal and Glaucoma Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Assess Eye Measurements in Patients Having Retina Pathology or Glaucoma
Lead sponsor: Optovue
Sponsor class: INDUSTRY
First posted: 2013-03-07
Enrollment: 135
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients will have retina pathology or glaucoma.

Brief summary: The purpose of the study is to repeatability, reproducibility and agreement of eye measurements in retina and glaucoma patients.

Detailed description: The purpose of the study is to repeatability, reproducibility and agreement of eye measurements in retina and glaucoma patients using OCT technology. There will be a series of measurements acquired from one eye on at least 2 different OCT devices. All testing will be completed in one visit.

Eligibility criteria: Inclusion Criteria:

Inclusion Criterea:

* At least 18 years of age
* Able and willing to provide consent
* Willing to complete the required examinations and visits
* Best corrected visual acuity equal or better than 20/100
* Retina subject must have clinical diagnosis of retinal pathology
* Glaucoma subjects must have clinical diagnosis of glaucoma

Exclusion Criteria:

* Unable to complete the required examinations and visits
* Poor OCT image quality as a result of media opacity, extreme refractive error or pathologies in the anterior segment
* Confounding pathology requiring surgical treatment or medical intervention

Primary outcomes:
measure: Retina thickness
timeFrame: Day 1
Secondary outcomes:
Other outcomes:
Locations:
city: Daly City
country: United States
facility: Pacific Eye Specialists
state: California
city: Petaluma
country: United States
facility: North Bay Eye Associates
state: California
city: Walnut Creek
country: United States
facility: West Coast Retinal Medical Group
state: California
Study officials:
References:
Clinical trial NCT03635502: What Are the Determinants of Explicit and Implicit Motor Imagery Ability in Stroke Patients?
Official title: What Are the Determinants of Explicit and Implicit Motor Imagery Ability in Stroke Patients?: A Controlled Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Stroke
Healthy
Lead sponsor: Istanbul Medeniyet University
Sponsor class: OTHER
Collaborators: name: Istanbul University
name: Bakırkoy Dr. Sadi Konuk Training and Research Hospital
First posted: 2018-08-17
Enrollment: 77
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Stroke patients and age, sex, education matched healthy volunteers who meet the inclusion criteria

Brief summary: Motor imagery (MI) might be described as a dynamic process in which an individual mentally stimulates an action without any overt movement. After stroke, motor imagery ability is impaired and also due to structure of MI, not every stroke patients is able to perform MI. Therefore, the aim of the study is a) to compare both explicit and implicit motor imagery ability (MIA) between patients with stroke and healthy subjects, b) to examine predictive effects of clinical characteristics for MIA after stroke.


Eligibility criteria: Inclusion Criteria:

* Being between the ages of 18-80,
* Having a unilateral stroke for the first time and 0-6 months since stroke onset
* 24 points and above in Mini Mental State Examination (MMDM)
* Not having a disease that may interfere with the study such as cardiac diseases, orthopedic conditions,etc.

Exclusion Criteria:

* Multiple strokes
* Sever cognitive dysfunction (\<24 points in MMDM)
* Unilateral neglect
* Upper extremity pain that interferes with the study or aggravated with movement
* Visual problems, aphasia or another sequel that might limit the assessment

Primary outcomes:
measure: Movement Imagery Questionnaire-3 (MIQ-3)
timeFrame: 15 min
measure: Chaotic Motor Imagery Assessment- Hand Rotation
timeFrame: 20 min
measure: Box and Block Test
timeFrame: 5 min
measure: Fugl-Meyer Assessment- Upper Extremity
timeFrame: 10 min
Secondary outcomes:
measure: Motor Activity Log-28
timeFrame: 5 min
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bakırköy Dr. Sadi Konuk Training and Research Hospital
Study officials:
References:
Clinical trial NCT06698302: Validation of COMPAT-SF Spanish Translation
Official title: Validation of COMPAT-SF Spanish Translation
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Chronic Pancreatitis
Lead sponsor: Methodist Health System
Sponsor class: OTHER
Collaborators: name: Aalborg University Hospital
First posted: 2024-11-20
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Spanish speaking subjects with CP diagnosis and a stable pain pattern with no new interventions or medications in the last three months

Brief summary: Prospective translation validation pilot study that will collect data from Spanish-speaking CP patients seen at Methodist Dallas Medical Center (MDMC) beginning June 2024 through July 2027, in order to validate a Spanish-translated COMPAT-SF instrument.

Detailed description: Prospective translation validation pilot study that will collect data from Spanish-speaking CP patients seen at Methodist Dallas Medical Center (MDMC) beginning June 2024 through July 2027, in order to validate a Spanish-translated COMPAT-SF instrument.

Eligibility criteria: Inclusion Criteria:

* 18 years or older in age
* Have a definite CP diagnosis and a stable pain pattern with no new interventions or medications in the last three months
* Able to read and understand the study information in Spanish
* Personally signed and dated ICF indicating that the subject has been informed of all pertinent aspects of the study
* Subject is willing and able to comply with the scheduled questionnaires

Exclusion Criteria:

* Subjects who do not meet the criteria in section 4.1

Primary outcomes:
measure: Face validity:
timeFrame: through study completion, up to 18 months
Secondary outcomes:
Other outcomes:
Locations:
city: Dallas
country: United States
facility: Methodist Dallas Medical Center- Clinical Research Institute
state: Texas
Study officials:
References:
Clinical trial NCT01380002: Home-Care Needs in Liver or Renal Transplantation Recipients and Their Spouses
Official title: Home-Care Needs in Liver or Renal Transplantation Recipients and Their Spouses
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Liver Transplant
Renal Transplant
Keywords: care needs
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
First posted: 2011-06-23
Enrollment: 400
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: FAMILY_BASED
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: * liver transplant recipients or renal transplant recipients with 18 to 80 years old who have regular follow up in organ transplant outpatient departments at National Taiwan University Hospital in Northern Taiwan.
* We will also recuit spouses who live with recruited patients.

Brief summary: * Liver/renal transplantations are now tending to be the most important treatment for terminal liver and renal disease. Although transplantation can prevent recipients from suffering with critical and fatal symptoms, patients may experience the complication from surgery and immunosuppressive drugs. Furthermore, they might have many unmet needs in daily life, and so as their spouses. The purpose of this study is to explore the home-care needs among the post liver or renal transplant recipients and their spouses, and identify the significant factors for care needs.
* A cross-sectional correlated design will be used and patients will be recruited by purposive sampling from an organ transplant outpatient department at a medical center in northern Taiwan. A set of structured questionnaires will be used to collect data.
* The result of this study will be helpful for clinical nurses to understand liver or renal recipients' physical and mental distress, also identify the potential risk of home-care needs and the degree of satisfaction as well.


Eligibility criteria: Inclusion Criteria:

* about patients

  1. liver transplant recipients or renal transplant recipients who have regular follow up in organ transplant outpatient departments.
  2. conscious clear.
  3. above 18 years old.
* about spouse

  1. who live with patients.
  2. conscious clear.
  3. above 18 years old.

Exclusion Criteria:

* about patients

  1. who suffer form cancer now.
  2. have received transplantation twice.
* about spouse

  1. who liver apart from patients.
  2. whose spouse(patient) did not recruited in this research.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital
Study officials:
affiliation: Department of Nursing
name: Shiow-Ching Shun, Doctor
role: STUDY_CHAIR
References: