Clinical trial NCT02288403: Interval Versus Continuous Training in Healthy Adults
Official title: Effects of a High-intensity Interval Training Program Compared to a Moderate Intensity Program in Adults 18-44 Years
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy Volunteers
Keywords: Aerobic Exercise
Oxygen Consumption
Blood Pressure
Lead sponsor: Universidad de Antioquia
Sponsor class: OTHER
First posted: 2014-11-11
Enrollment: 44
Sex: MALE
Minimum age (years): 18
Maximum age (years): 44
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Aerobic exercise produces increases in cardiorespiratory fitness (CF), which constitute a protective factor for cardiovascular disease and all-cause mortality. Therefore, aerobic exercise is a key strategy to promoting cardiovascular. There is some evidence that aerobic high intensity interval training may lead to greater increases in CF compared with continuous moderate-intensity training.

The main objective of this study is to examine the effects of an aerobic high intensity training program versus a continuous moderate intensity training program on CF in men 18 to 44 years.

Detailed description: Forty-four individuals will be randomly assigned to one of two aerobic training programs on a treadmill. Both groups will performed three times a week for eight-weeks (on alternate days). Half will run 40 minutes of continuous exercise at an intensity between 65-75% of maximum heart rate, and the remaining 22 will complete 21.5 minutes of interval exercise at an intensity between 90-95% of maximum heart rate, with recoveries between 50-55 % of maximum heart rate. After each session both groups will complete eight strength exercises mainly including large muscle groups for two sets and 8-12 repetitions at an intensity equivalent to 60-70% of one repetition maximum (controlled by perceived effort). Rest between sets will be kept between 60 and 90 seconds.

All participants will be evaluated at the start and completion of the intervention for their maximal oxygen consumption, blood pressure, waist circumference, BMI, body composition, and steps per week.

Eligibility criteria: Inclusion Criteria:

* Perform aerobic exercise maximum 3 sessions per week

Exclusion Criteria:

* Currently participating in an aerobic high intensity training program
* Smoker
* History of cardiovascular disease
* History of coronary heart disease
* Arrhythmias
* Heart failure/insufficiency
* Hypertension
* Diabetes
* Under medical treatment with anticoagulants, beta-blockers, calcium antagonists, bronchodilators, and/or steroids
* Psychological, neuromotor and/or osteo-muscular conditions that may affect participation in an exercise program.

Primary outcomes:
measure: Change in maximal oxygen uptake
timeFrame: Baseline and 8-weeks
Secondary outcomes:
measure: Change in systolic blood pressure
timeFrame: Baseline and 8-weeks
measure: Change in diastolic blood pressure
timeFrame: Baseline and 8-weeks
Other outcomes:
Locations:
city: Medellín
country: Colombia
facility: Universidad de Antioquia
state: Antioquia
Study officials:
affiliation: Associate Professor
name: Víctor H Arboleda, MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Associate Professor
name: Elkin F Arango, MD. MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Professor
name: Rubén D Gómez, PhD. MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Assistant Professor
name: Yuri Feito, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Arboleda-Serna VH, Feito Y, Patino-Villada FA, Vargas-Romero AV, Arango-Velez EF. Effects of high-intensity interval training compared to moderate-intensity continuous training on maximal oxygen consumption and blood pressure in healthy men: A randomized controlled trial. Biomedica. 2019 Sep 1;39(3):524-536. doi: 10.7705/biomedica.4451.
citation: Arboleda Serna VH, Arango Velez EF, Gomez Arias RD, Feito Y. Effects of a high-intensity interval training program versus a moderate-intensity continuous training program on maximal oxygen uptake and blood pressure in healthy adults: study protocol for a randomized controlled trial. Trials. 2016 Aug 18;17:413. doi: 10.1186/s13063-016-1522-y.