louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02778984: Facial Mask Tightness: A Comparative Study
Official title: Facial Mask Tightness: A Comparative Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anesthesia
Keywords: Anesthesia
facial mask
Lead sponsor: University Hospital, Limoges
Sponsor class: OTHER
First posted: 2016-05-20
Enrollment: 70
Sex: ALL
Minimum age (years): 55
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: A correct preoxygenation can be obtained after a 3min delay of calm ventilation through a tight mask thereafter mask is used to make the patient breathing before intubation. Most tight masks are actually sold but they have never been compared in studies. The aim of this study is to compare air leaks with standard facial mask and QuadraLite masks during preoxygenation and induction of anesthesia.


Eligibility criteria: Inclusion Criteria:

* edentulous patients
* age \> 55 years

Exclusion Criteria:

* pregnancy or breast-feeding, patients on tutelage or guardianship
* patient unable to understand the protocol
* anesthesia in emergency or with full stomach

Primary outcomes:
measure: significant leakage (ie greater than 20% of the current volume) between QuadraLite® mask and facial mask
timeFrame: 10 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Limoges
country: France
facility: Limoges Hospital
Study officials:
References:
Clinical trial NCT06947902: Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures
Official title: Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures: a Randomized Study
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Airway Disorder
Keywords: High Flow Nasal Cannula (HFNC)
Lead sponsor: The University of Texas Health Science Center, Houston
Sponsor class: OTHER
First posted: 2025-04-27
Enrollment: 80
Sex: ALL
Minimum age (years): 0
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The purpose of this study is to investigate which flow rate (higher versus lower) is most effective at increasing apneic time and preventing greater than 5% drop in desaturation, as well as assessing transcutaneous carbon dioxide (CO2) levels during airway procedures in children


Eligibility criteria: Inclusion Criteria:

* undergoing laryngoscopy and bronchoscopy procedures at Children's Memorial Hermann Hospital (CMHH)
* weight greater than or equal to 5 kilograms and using flow rates between 5 to 45 liters per minute (BTPS)

Exclusion Criteria:

* Emergency type cases, tracheostomy patients, unrepaired cyanotic heart disease, nasal deformity/choanal atresia, or cautery/laser type procedures

Primary outcomes:
measure: Number of participants that show an incidence of oxygen desaturation >5 %
timeFrame: from start of procedure to end of procedure (about 1 hour)
Secondary outcomes:
measure: Apnea time measured in seconds or minutes
timeFrame: from start of procedure to end of procedure (about 1 hour)
measure: Number of Participants With Surgical Interruptions Due to Desaturation
timeFrame: from start of procedure to end of procedure (about 1 hour)
measure: Oxygen nadir level
timeFrame: from start of procedure to end of procedure (about 1 hour)
measure: Transcutaneous CO2 measurements throughout procedure
timeFrame: from start of procedure to end of procedure (about 1 hour)
measure: Adverse events related to device itself (nasal pain, skin irritation)
timeFrame: from baseline to end of study (1 month after baseline)
Other outcomes:
Locations:
city: Houston
country: United States
facility: The University of Texas Health Science Center at Houston
state: Texas
Study officials:
affiliation: The University of Texas Health Science Center, Houston
name: Zhen Huang, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06248502: Examining the Relationship Between Pain, Upper Extremity Functionality and Depression in Individuals With Chronic Shoulder Pain
Official title: Examining the Relationship Between Pain, Upper Extremity Functionality and Depression in Individuals With Chronic Shoulder Pain
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Shoulder Pain
Lead sponsor: Tokat Gaziosmanpasa University
Sponsor class: OTHER
First posted: 2024-02-08
Enrollment: 44
Sex: ALL
Minimum age (years): 30
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Shoulder pain

Brief summary: The aim of the study is to examine the relationship between pain, upper extremity functionality and depression in individuals with chronic shoulder pain.


Eligibility criteria: Inclusion Criteria:

* Have been suffering from shoulder pain for more than three months

Exclusion Criteria:

* People who have had shoulder surgery

Primary outcomes:
measure: QuickDASH
timeFrame: Baseline
measure: Pain Quality Rating Scale
timeFrame: Baseline
measure: Beck Depression Inventory
timeFrame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Tokat
country: Turkey
facility: Faculty of Health Sciences, Tokat Gaziosmanpaşa University
Study officials:
References:
Clinical trial NCT00990002: Investigation of A Children's Beverage Containing Different Probiotics
Official title: INVESTIGATION OF CHANGES IN LEUKOCYTE POPULATIONS AMONG CHILDREN RECEIVING A FOLLOW-ON COW'S MILK-BASED FORMULA CONTAINING DIFFERENT BIOACTIVE INGREDIENTS.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Immunity
Lead sponsor: Mead Johnson Nutrition
Sponsor class: INDUSTRY
Collaborators: name: Father Flanagan's Boys' Home
First posted: 2009-10-06
Enrollment: 30
Sex: ALL
Minimum age (years): 2
Maximum age (years): 4
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: children 2-4 years of age

Brief summary: Investigating different bioactive ingredients in children's beverages and the effect on blood serum markers.


Eligibility criteria: Inclusion Criteria:

* Children 2-4 years of age, weight and length for age within the 10th to 90th percentiles as plotted on the NCHS growth chart
* Consuming cow's milk for at least one month

Exclusion Criteria:

* Serious concurrent illness or acute infection
* Using systemic antibiotics or steroids
* Recent probiotic use
* Feeding difficulties or intolerance to cow's milk
* Conditions effecting normal growth and development
* Immunodeficiencies

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Boys Town
country: United States
facility: Boys Town National Research Hospital
state: Nebraska
Study officials:
References:
Clinical trial NCT02188602: Effect of Cumulative Chloride Dose on Development of Acute Kidney Injury in Critically Ill Children
Official title: Retrospective Investigation of Chloride Dosing and Its Effect on Acute Kidney Injury
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Acute Kidney Injury
Lead sponsor: Stanford University
Sponsor class: OTHER
First posted: 2014-07-11
Enrollment: 0
Sex: ALL
Minimum age (years): 1
Maximum age (years): 18
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Children \< 18 yo admitted to the Pediatric Intensive Care Unit at Lucile Packard Children's Hospital with admitting diagnosis of sepsis, respiratory failure, or liver failure

Brief summary: The investigators would like to investigate the effect of chloride dosing on the development of acute kidney injury in critically ill patients. The investigators hypothesis is that administering intravenous fluids with higher chloride content are more likely to lead to acute kidney injury.

Detailed description: Retrospective chart review from 2008-2012 evaluating chloride dosing and serum chloride levels and their effects on acute kidney injury in the pediatric ICU. Patients will be included for the first seven days of their PICU stay.

Eligibility criteria: Inclusion Criteria:

* age less than 18 years
* PICU admitting diagnosis of sepsis, respiratory failure, or hepatic failure.

Exclusion Criteria:

* hyponatremia or hypernatremia at PICU admission
* preexisting diagnosis of End-stage renal disease or renal transplant
* presence of neurologic comorbidities.

Primary outcomes:
measure: Acute Kidney Injury
timeFrame: 7 days
Secondary outcomes:
measure: PICU length of stay
timeFrame: 7 days
measure: Hospital length of stay
timeFrame: 7 days
measure: Number of ventilator days
timeFrame: 7 days
measure: Mortality
timeFrame: 7 days
Other outcomes:
Locations:
city: Palo Alto
country: United States
facility: Lucile Packard Children's Hospital
state: California
Study officials:
affiliation: Stanford University
name: Weiwen V Shih, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02751502: Home Based Adaptive Arm Training for Children
Official title: Home Based Adaptive Arm Training for Children With Hemiplegia
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Hemiplegia
Keywords: Children
Pediatrics
Arm
Upper limb
bimanual training
physical training
Lead sponsor: NYU Langone Health
Sponsor class: OTHER
First posted: 2016-04-26
Enrollment: 4
Sex: ALL
Minimum age (years): 5
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Twenty pediatric patients aged 5-17 years with Acquired Brain Injuries (ABI) will be randomized to receive either a bimanual-to-unimanual device home training program (10 subjects) or a conventional non-device home training program (10 subjects) for a period of 6 weeks.

The specific aims of this proposal are to:

Aim 1: Introduce home-based targeted upper limb training in children with hemiplegia from ABI (Acquired Brain Injuries) using a bimanual-to-unimanual training approach It is hypothesized that child-friendly home-based upper limb bimanual-to-unimanual training will lead to greater compliance and improved motor outcome on the Fugl Myer Scale compared to a conventional home training program.

Aim 2: Improve the understanding of the pattern of recovery of isolated joint movements in the pediatric population with hemiplegia following ABI.

It is hypothesized that individuals receiving device-based bimanual-to-unimanual training will show improvement in active range of motion across upper limb joints compared with a conventional home training program.


Eligibility criteria: Inclusion Criteria:

* Acquired Brain Injury at least 3 months prior to enrollment.
* Unilateral hemiparesis
* History of compliance with home exercise programs in the past.

Exclusion Criteria:

* Any social or medical problem that precludes compliance with the protocol
* Comorbid seizure disorder or other neurological disease
* Treatment with botulinum toxin or intrathecal baclofen in the 3 months preceding enrollment
* Implanted neuromodulatory or electronic device or other complicating illness
* Lack of capacity to consent

Primary outcomes:
measure: Change From Baseline in Quality of Bimanual Hand Measured by Fugl-Meyer Scale
timeFrame: 6 Weeks
measure: Change From Baseline in Timed Performance of Standardized Manual Activities Measured by Hand Assessment Test
timeFrame: 6 Weeks
Secondary outcomes:
Other outcomes:
Locations:
city: New York
country: United States
facility: New York University Langone Medical Center
state: New York
Study officials:
affiliation: NYU Langone Health
name: Renat Sukhov, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03170102: Building Capacity of OT Students to Address Children's Mental Health During Fieldwork (OTFW)
Official title: Building Capacity of OT Students to Address Children's Mental Health During Fieldwork
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Education
Keywords: occupational therapy
Lead sponsor: Cleveland State University
Sponsor class: OTHER
First posted: 2017-05-30
Enrollment: 18
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: A The study involved a one-group (n=19) mixed methods design using using pretest-posttest surveys and qualitative analysis of written reflections.
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The study involved a one-group (n=19) mixed methods design using using pretest-posttest surveys and qualitative analysis of written reflections was used to explore the meaning and outcomes of participation in the building capacity process.

Detailed description: To explore the meaning and outcomes of a four-month building capacity process designed to promote knowledge translation of a public health approach to mental health with children and youth among occupational therapy students completing a Level II Fieldwork experience in school-based practice.The study involved a one-group (n=19) mixed methods design using using pretest-posttest surveys and qualitative analysis of written reflections was used to explore the meaning and outcomes of participation in the building capacity process.The building capacity process expanded student knowledge of a public health approach to mental health resulting in increased awareness and application of embedded strategies addressing mental health during a Level II Fieldwork experience in a school settings.

Eligibility criteria: Inclusion Criteria:

* Occupational therapy (OT) students completing a Level II Fieldwork experience during Fall 2016 in a school setting
* OT students meeting the above criteria who agree to participate in the study

Exclusion Criteria:

- OT students completing a FW experience in settings other than schools during Fall 2016

Primary outcomes:
measure: Change in knowledge, beliefs, and actions regarding addressing children's mental health in a school-based fieldwork experience
timeFrame: 2 weeks
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
affiliation: Cleveland State University
name: Susan Bazyk, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02898402: Study on Seroprevalence and Risk Factors of Coxiella Burnetii (Q Fever) in the South of Reunion Island
Official title: Study on Seroprevalence and Risk Factors of Coxiella Burnetii (Q Fever) in the South of Reunion Island
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: q Fever
Lead sponsor: Centre Hospitalier Universitaire de la Réunion
Sponsor class: OTHER
First posted: 2016-09-13
Enrollment: 3500
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: ECOLOGIC_OR_COMMUNITY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: pregnant women coming to hospital for delivery

Brief summary: Emergent and infectious diseases are a public health priority on Reunion Island. Amongst public health threats, the infection due to Coxiella burnetii (Q fever) seems to have appeared on Reunion island in 2007 with two hospitalised confirmed cases (one death) and one probable case with a goat farmer.

According to the investigator, the diffusion of C. burnetti is more ancient and such diagnosis have been made in the last 30 years with 80 positive serologies identified between 2005 and 2011.

Considering the high epidemic power of this disease, its often silent clinical expression and its life-threatening condition, the principal investigator wishes to perform a sero-epidemiological study in order to establish or to reject the risk of emergence of Q fever in Reunion island.

The study will be performed on pregnant women because Q fever is responsible for particular complications during pregnancy and because the number of pregnancy followed on Reunion island is stable from one year to the other. The pregnant women population presenting the same exposure criteria as the general population, this population will be used to extrapolate to the general population of the island.


Eligibility criteria: Inclusion Criteria:

* all pregnant women coming to the two maternity hospitals located in the south of Reunion island during inclusion period who have been informed and gave consent to participate to the study.

Exclusion Criteria:

* women aged less than 18 years old.
* women who did not give their consent
* women for whom it is not possible to perform the blood sample.

Primary outcomes:
measure: prevalence of Coxiella burnetii infection in general population in the south of Reunion island
timeFrame: at inclusion
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT00827502: Trulimax (Azithromycin ) Non-Interventional Study In Acute Bacterial Upper Respiratory Tract Infections
Official title: Trulimax (Azithromycin ) Non-Interventional Study In Acute Bacterial Upper Respiratory Tract Infections
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Upper Respiratory Tract Infections
Keywords: TRULIMAX (AZITHROMYCIN ) NON-INTERVENTIONAL STUDY
Lead sponsor: Pfizer
Sponsor class: INDUSTRY
First posted: 2009-01-22
Enrollment: 421
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Only patients with acute URTI, presumed to be of bacterial origin as per the clinical judgment of the investigator will be enrolled in the study.

Brief summary: To assess effectiveness of Trulimax (Azithromycin) in Acute Bacterial Upper Respiratory Tract Infections (URTIs).

Detailed description: Prospective, Open-label, Non-interventional and Multi-center Study NA

Eligibility criteria: Inclusion Criteria:

* Evidence of a personally signed and dated informed consent document indicating that the subject (or a legally acceptable representative) has been informed of all pertinent aspects of the study.
* Patients with acute URTI, presumed to be of bacterial origin as per the clinical judgment of the investigator.

Exclusion Criteria:

N/A

Primary outcomes:
measure: Number of Subjects With an Investigator Assessment of Clinical Outcome (Success/Failure) at End of Study
timeFrame: Baseline to 2 weeks
measure: Number of Subjects With an Investigator Assessment of Clinical Outcome (Cure/Improvement/Failure) at End of Study
timeFrame: Baseline to 2 weeks
Secondary outcomes:
measure: Cost (in Indian Rupees) Per Participant of Utilizations Including General Consultations, Medications, Chest X-ray, Complete Blood Count, and Erythrocyte Sedimentation Rate
timeFrame: Baseline to 3 months
Other outcomes:
Locations:
city: Jn Vishakhapatnam
country: India
facility: Pfizer Investigational Site
state: Andhra Pradesh
city: Visakhapatnam
country: India
facility: Pfizer Investigational Site
state: Andhra Pradesh
city: Guwhati
country: India
facility: Pfizer Investigational Site
state: Assam
city: New Delhi
country: India
facility: Pfizer Investigational Site
state: Delhi
city: New delhi
country: India
facility: Pfizer Investigational Site
state: Delhi
city: Nagpur
country: India
facility: Pfizer Investigational Site
state: Maharashtra
city: Vashi
country: India
facility: Pfizer Investigational Site
state: Maharashtra
city: Delhi
country: India
facility: Pfizer Investigational Site
state: New Delhi
city: Chennai
country: India
facility: Pfizer Investigational Site
state: Tamil Nadu
city: Chennai
country: India
facility: Pfizer Investigational Site
state: Tamil Nadu
city: Lucknow
country: India
facility: Pfizer Investigational Site
state: Uttar Pradesh
Study officials:
affiliation: Pfizer
name: Pfizer CT.gov Call Center
role: STUDY_DIRECTOR
References:
Clinical trial NCT06264102: Influence of Dalcroze Eurhythmics on Pains in Older Women
Official title: Effect of Dalcroze Eurhythmics' Physical Exercises on Headaches, Backaches, and Leg Pains in Older Women: a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Back Pain
Headache
Leg Pain
Keywords: headache
elderly women
Dalcroze Eurhythmics
back pain
leg pain
Lead sponsor: Poznan University of Physical Education
Sponsor class: OTHER
First posted: 2024-02-16
Enrollment: 61
Sex: FEMALE
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: In this study, we attempted to answer the question of whether participation in a 12-week rhythmic exercise program using the Dalcroze method affects the level of intensity of pain experienced by women over the age of 65. The level of pain was determined on a numerical scale from 1 to 10 and involved headaches, back pain and leg pain.

Detailed description: Background. Body pain of various degrees and types can complicate human life. Regular physical exercise and good mental health can both have protective effects on the body and its physical health. Physical exercises may also, in some aspects, be particularly important for older women who experience varying degrees of headache, back pain, and/or leg pain chronically. The purpose of the study was to analyze the effects of the Dalcroze Eurhythmic Method on headaches, backaches, and leg pains among older women.

Methods. Sixty-two blinded participants with pain were randomized into two groups. Women (65 to 82 years old) who had reported the occurrence of headaches, backaches, or leg pains during the 3 months prior to the beginning of the randomized controlled trial study were identified. The participants in the pre-test and post-test used the 0-10 Numeric Pain Rating Scale to quantify their pain. Women from the experimental group participated for 3 months in the physical exercise program based on the Dalcroze Eurhythmics Method.

Eligibility criteria: Inclusion Criteria:

* female, 65+ years old, physical and mental state that allows them to participate in the exercise program (ability to follow the instructions), community dwelling

Exclusion Criteria:

* taking analgesics indelibly, Parkinson's or Alzheimer's disease, using social assistance or nursing care.

Primary outcomes:
measure: Pain levels before exercise program
timeFrame: From enrollment to the day before the start of the exercise program
Secondary outcomes:
measure: Results of pain levels after exercise program
timeFrame: One month after completion of the exercise program
Other outcomes:
Locations:
city: Poznań
country: Poland
facility: Poznan University of Physical Education
state: Wielkopolska
Study officials:
affiliation: Poznan University of Physical Education
name: JANUSZ MACIASZEK, PROF
role: STUDY_DIRECTOR
References: