Clinical trial NCT04211779: a-tDCS Combined With Aerobic Exercise in Healthy Individuals
Official title: The Effect of Anodal Transcranial Direct Current Stimulation Combined With Aerobic Exercise on Performance in Healthy Individuals
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Healthy
Keywords: Transcranial Direct Current Stimulation
Aerobic Exercise
Performance
Lead sponsor: Marmara University
Sponsor class: OTHER
First posted: 2019-12-26
Enrollment: 21
Sex: MALE
Minimum age (years): 20
Maximum age (years): 25
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this study is to assess the effects on the exercise performance of anodal transcranial direct current stimulation combined with aerobic exercise in healthy individuals.

Detailed description: Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation method that has become increasingly popular in recent years. tDCS shows promising improvements for the motor performance of healthy individuals as well as pathological conditions. Moreover, it is frequently preferred because of its safety advantage, high tolerability as well as being cheap, portable and easily applicable.

Studies have shown that tDCS can modulate the excitability of both cortical and subcortical brain regions. In recent years, there have been scientific studies investigating the effects of tDCS on improving physical performance in healthy individuals, but these studies are limited in number, their results are conflicted and as far as the investigators know there is no study that combines tDCS with exercise.

Moreover, although the mechanisms of tDCS on physical performance are largely unknown, some tDCS devices are open to public usage and a large number of professional athletes have reported using tDCS during their training programs. Therefore, studies are needed to demonstrate the effects of tDCS which combined with exercise on performance.

The aim of this study was to investigate the effects of anodal transcranial direct current stimulation combined with aerobic exercise on physical performance in healthy individuals.

Eligibility criteria: Inclusion Criteria:

* Healthy subject
* No use of any ergogenic substance in one year
* No history of active exercise training in last 6 months

Exclusion Criteria:

* Pacemaker
* Intracerebral metallic implant
* Using dietary supplementation or medication potentially affecting the CNS
* Musculoskeletal injury within the past 6 weeks
* Lower extremity pain above 3 or more according to numeric pain scale
* History of epilepsy or convulsive crisis

Primary outcomes:
measure: Effect of tDCS combined with aerobic exercise on exercise performance in healthy individuals.
timeFrame: 2 months
measure: Effect of tDCS combined with aerobic exercise on ratings of perceived exertion (RPE) in healthy individuals.
timeFrame: 2 months
Secondary outcomes:
measure: Effect of tDCS combined with aerobic exercise on isokinetic muscle strength in healthy individuals.
timeFrame: 2 months
Other outcomes:
measure: Changes in SF-36 questionnaire of quality of life
timeFrame: 2 months
measure: Changes in Cognitive Test Battery
timeFrame: 2 months
Locations:
city: İstanbul
country: Turkey
facility: Marmara University
Study officials:
affiliation: Marmara University
name: Mine Gülden Polat, PhD
role: STUDY_DIRECTOR
affiliation: Medipol University
name: Lütfü Hanoğlu, PhD
role: STUDY_CHAIR
References: