Clinical trial NCT03084172: Systemic Redesign and Demonstration for Early Detection, Evaluation and Management of Chronic Kidney Disease in Shanghai
Official title: Systemic Redesign and Demonstration for Early Detection, Evaluation and Management of Chronic Kidney Disease in Shanghai
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Chronic Kidney Diseases
Lead sponsor: Shanghai Changzheng Hospital
Sponsor class: OTHER
Collaborators: name: Shanghai Municipal Commission of Health and Family Planning
name: Shanghai Municipal Center for Disease Control and Prevention
name: Huashan Hospital
name: Shanghai Minhang district Municipal Center for Disease Control and Prevention
name: Shanghai Jing'an district Municipal Center for Disease Control and Prevention
name: Fudan University
name: Minhang District Central Hospital of Shanghai
name: Jing'an District Central Hospital of Shanghai
name: Jing'an District Zhabei Central Hospital of Shanghai
name: Jing'an District Shibei Hospital of Shanghai
name: Linfen Community Health Services Center of Shanghai
name: Pengpu Community Health Services Center of Shanghai
name: Pengpu zhen Community Health Services Center of Shanghai
name: Da'ning Community Health Services Center of Shanghai
name: Gonghexin Community Health Service Center of Shanghai
name: Zhijiangxi Road Community Health Service Center of Shanghai
name: Tianmuxi Road Community Health Service Center of Shanghai
name: Beizhan Community Health Service Center of Shanghai
name: Baoshan Community Health Services Center of Shanghai
name: West Nanjing road Community Health Services Center of Shanghai
name: Second Shimen Road Community Health Service Center of Shanghai
name: Jiangning Road Community Health Service Center of Shanghai
name: Caojiadu Community Health Service Center of Shanghai
name: Jing'an Temple Community Health Service Center of Shanghai
name: Xinzhuang Community Health Service Center of Shanghai
name: Longbai Community Health Service Center of Shanghai
name: Gumei Community Health Service Center of Shanghai
name: Xinhong Community Health Service Center of Shanghai
name: Huacao Community Health Service Center of Shanghai
name: Hongqiao Community Health Service Center of Shanghai
name: Qibao Community Health Service Center of Shanghai
name: Meilong Community Health Service Center of Shanghai
name: Jiangchuan Community Health Service Center of Shanghai
name: Zhuanqiao Community Health Service Center of Shanghai
name: Maqiao Community Health Service Center of Shanghai
name: Wujing Community Health Service Center of Shanghai
name: Pujiang Community Health Service Center of Shanghai
First posted: 2017-03-20
Enrollment: 2000000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The residents in Jing'an District and Minhang District, which medical services are provided by those collaborative Community Health Service Center.

Brief summary: Based on clinical evidence based medicine and organizational management model, investigators redesign the prevention and treatment of chronic kidney disease of public health system in Shanghai China. The investigators hope to find early chronic kidney disease, prevention and clinical intervention of orderly combination. The advantages of this system were confirmed by comparing the prevalence rate, awareness rate and treatment rate before and after the completion of the system.

Detailed description: The whole study mainly includes the following parts:

1. Establishment of a database of patients with kidney disease, and training data entry specialist in every center.
2. Conduct propaganda of kidney disease knowledge, training professional doctors in center hospital and community hospital.
3. Search for high-risk patients, and screening for patients with kidney disease from community residents in community hospital.
4. Establishment of a standardized and orderly patient referral process from community hospital to center hospital or three level of first-class hospital.

Eligibility criteria: Inclusion Criteria:

* Over 18 years of age.
* Signed informed consent

Exclusion Criteria:

* Refused to accept the blood and urine test

Primary outcomes:
measure: prevalence rate of chronic kidney disease
timeFrame: baseline and 12 months, an average of 3 years
measure: awareness rate of chronic kidney disease
timeFrame: baseline and 12 months, an average of 3 years
measure: treatment rate of chronic kidney disease
timeFrame: baseline and 12 months, an average of 3 years
measure: The degree of decreased glomerular filtration rate in chronic kidney patients
timeFrame: through study completion, an average of 3 years
Secondary outcomes:
Other outcomes:
Locations:
city: Shanghai
country: China
facility: Changzheng Hospital
state: Shanghai
city: Shanghai
country: China
facility: Huashan Hospital
state: Shanghai
city: Shanghai
country: China
facility: Jiangning Road Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Jing'an District Central Hospital of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Jing'an Temple Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Second Shimen Road Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: West Nanjing road Community Health Services Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Caojiadu Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Jing'an District Zhabei Central Hospital of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Tianmuxi Road Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Zhijiangxi Road Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Baoshan Community Health Services Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Beizhan Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Da'ning Community Health Services Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Gonghexin Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Pengpu zhen Community Health Services Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Jiangchuan Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: The Fifth People's Hospital of Shanghai, Fudan University
state: Shanghai
city: Shanghai
country: China
facility: Wujing Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Linfen Community Health Services Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Pengpu Community Health Services Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Jing'an District Shibei Hospital of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Minhang District Central Hospital of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Xinhong Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Xinzhuang Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Qibao Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Gumei Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Hongqiao Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Meilong Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Longbai Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Huacao Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Zhuanqiao Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Maqiao Community Health Service Center of Shanghai
state: Shanghai
city: Shanghai
country: China
facility: Pujiang Community Health Service Center of Shanghai
state: Shanghai
Study officials:
affiliation: Shanghai Changzheng Hospital
name: Changlin Mei, Master
role: PRINCIPAL_INVESTIGATOR
References: