Clinical trial NCT05794438: Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History
Official title: Gamified Adaptive Approach Bias Modification on Individuals With Methamphetamine Use History
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Addiction, Substance
Lead sponsor: Adai Technology (Beijing) Co., Ltd.
Sponsor class: OTHER
First posted: 2023-04-03
Enrollment: 139
Sex: ALL
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A randomized controlled trial will be conducted to investigate whether a proposed algorithm that adjusts the congruency ratio based on the user's performance and difficulty can enhance the effectiveness of approach bias modification. Methamphetamine users will be recruited and randomized into an algorithm group, a standard group, and a control group.

Detailed description: To assess the efficacy of an adaptive approach bias modification (A-ApBM) paradigm with gamified designs and dynamic difficulty adjustments in reducing cue-induced craving in individuals with methamphetamine use history. DESIGN: Randomized controlled trial with three study groups: Adaptive ApBM (A-ApBM), Static ApBM (S-ApBM), and control. A-ApBM and S-ApBM groups engaged in ApBM training using a smartphone application for four weeks. A-ApBM used an adaptive algorithm to dynamically adjust the difficulty level based on individual performance, while S-ApBM had a static difficulty level. Cue-induced craving scores were assessed using a visual analog scale at baseline, post-intervention, and at week-16 follow-up.

Eligibility criteria: Inclusion Criteria:

• having a history of methamphetamine use of at least one year

Exclusion Criteria:

* could not fluently operate an Android or an iOS smartphone
* having mental health conditions other than MUD

Primary outcomes:
measure: Cue induced craving for methamphetamine
timeFrame: Baseline
measure: Cue induced craving for methamphetamine
timeFrame: Immediately Post-intervention
measure: Cue induced craving for methamphetamine
timeFrame: 16 week from baseline assesment
Secondary outcomes:
Other outcomes:
Locations:
city: Guanghan
country: China
facility: Gao Ping Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Han Zhou Street Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Jin Lun Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Jin Yan Street Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Jin Yu Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Lian Shan Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Nan Feng Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: San Shui Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Sanxingdui Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: SixTwentySix Service Center, Luo Cheng Street, Guanghan City
state: Sichuan
city: Guanghan
country: China
facility: Xiang Yang Town Community Drug Rehabilitation Center
state: Sichuan
city: Guanghan
country: China
facility: Xiao Han Town Community Drug Rehabilitation Center
state: Sichuan
Study officials:
References: