Clinical trial NCT02584764: Internet Supported Group Cognitive Behavior Therapy (CBT) for Hoarding Disorder (HD)
Official title: Internet Supported Group Cognitive Behavior Therapy for Hoarding Disorder - A Pilot Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hoarding Disorder
Lead sponsor: Karolinska Institutet
Sponsor class: OTHER
First posted: 2015-10-23
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The primary aim is to develop, and test the feasibility and efficacy of, a manual based, cognitive behaviour therapy (CBT) treatment for Hoarding Disorder (HD) delivered in a group format combined with an Internet support system. The investigators' secondary aim is to investigate the neurocognitive profile of the participants before and after treatment in order to explore if the treatment might have an impact on neurocognitive functioning and if certain neurocognitive profiles predict outcome.

For the primary aim, the investigators hypothesize that the treatment will be acceptable to participants and decrease symptoms of hoarding. Regarding the secondary aim, the investigators hypothesize that deficiencies in executive functioning, as measured with a neurocognitive battery, will reduce upon completion of treatment and that baseline executive function will be associated with treatment outcome.


Eligibility criteria: * Inclusion criteria:

  * Outpatients
  * Male or female
  * ≥ 18 years of age
  * Currently living in Stockholm county
  * Primary diagnosis of Hoarding Disorder according to DSM-5
  * Signed informed consent
  * Regular access to a computer with Internet and ability to use Internet
  * Access to a mobile phone
  * Able to participate in group sessions
* Exclusion criteria:

  * Current substance dependence or misuse
  * Life time bipolar disorder or psychosis
  * Severe self-rated depressive symptoms (score ≥ 35 on MADRS-S)
  * Suicidal ideation (score \> 4 on item 9 in MADRS-S)
  * Psychotropic medication changes within two months prior to the treatment
  * Other current psychological treatment that could affect hoarding symptoms
  * Has received more than 10 CBT sessions for Hoarding Disorder

Primary outcomes:
measure: Saving Inventory - Revised (SI-R)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Secondary outcomes:
measure: Hoarding Rating Scale - Self Report (HRS-SR)
timeFrame: Weekly change during treatment, weeks 1-15
measure: Saving Cognitions Inventory (SCI)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: Clutter Image Rating (CIR)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: Global Assessment of Functioning (GAF)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: Clinical global impression (CGI)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: EuroQol- 5 Dimension (EQ-5D)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: Trimbos and Institute of Medical Technology Assessment Cost Questionnaire for Psychiatry (TIC-P)
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
Other outcomes:
measure: Hoarding disorder diagnosis
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: Comorbid psychiatric diagnoses
timeFrame: Change from baseline to treatment week 8,16, 3- and 12-month follow-up
measure: Neuropsychological Test Battery (CANTAB)
timeFrame: Change from baseline to treatment week 16
measure: Client Satisfaction Questionnaire - 8 (CSQ-8)
timeFrame: At treatment week 16
measure: Homework adherence
timeFrame: Weekly change during treatment, weeks 1-15
Locations:
city: Stockholm
country: Sweden
facility: Psykiatri Nordväst, Stockholms Läns Sjukvårdsområde (SLSO), Stockholms Läns Landsting
Study officials:
affiliation: Karolinska Institutet
name: Christian Rück, Assoc Prof
role: PRINCIPAL_INVESTIGATOR
References: