Clinical trial NCT04431921: Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors
Official title: Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Lung Neoplasm
Survivorship
Keywords: Respiratory muscles
Pain
Cognitive dysfunction
Lead sponsor: Hacettepe University
Sponsor class: OTHER
First posted: 2020-06-16
Enrollment: 60
Sex: ALL
Minimum age (years): 45
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Lung cancer patients -\> patients who were not under active cancer treatments Healthy -\> No lung disease and systemic disease that affected outcome measure

Brief summary: Serious side effects occurs with disease and treatments in survival after lung cancer. For this reason, functional capacity, cognitive status, pain perception and respiratory functions may be affected in lung cancer. The purpose of this study was to evaluate respiratory function, respiratory muscle strength and endurance, functional capacity, pain, cognitive status level, and physical activity in lung cancer patients and compare with the findings of healthy subjects

Detailed description: This study was participated lung cancer patients survivors. Patients' pulmonary function test, functional capacity, respiratory muscle strength and endurance, pain and cognitive status was assessed and recorded.

Pulmonary function testing (PFT), mouth pressure measurement (MIP- maximal inspiratory pressure and MEP- maximal expiratory pressure), respiratory muscle endurance test, six minute walk test (6MWT) and pain threshold and tolerance test were used. In addition to physiological measurements, the Montreal Cognitive Assessment (MoCA) scale was used to evaluate cognitive status, the International Physical Activity Questionnaire (IPAQ) was used to determine the level of physical activity.

Eligibility criteria: Inclusion Criteria:

* Cooperation
* lung cancer patients who had a stable condition

Exclusion Criteria:

* Active cancer treatments
* Brain metastasis story
* Any orthopedic disease impairs walking, balance

Primary outcomes:
measure: Functional capacity
timeFrame: 15 minutes
Secondary outcomes:
measure: Respiratory muscle strength assessment
timeFrame: 10 minutes
measure: Respiratory muscle endurance
timeFrame: 10 minutes
measure: Pulmonary functions test
timeFrame: 15 minutes
measure: Cognition using MoCA-Test
timeFrame: 10 minutes
measure: Pressure pain threshold assessment
timeFrame: 15 minute
measure: Pressure pain tolerance assessment
timeFrame: 15 minute
measure: Physical activity level
timeFrame: 5 minutes
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Hacettepe University
Study officials:
affiliation: Hacettepe University
name: Naciye Vardar-Yagli, PhD
role: STUDY_DIRECTOR
affiliation: Hacettepe University
name: Deniz Inal-Ince, Professor
role: STUDY_CHAIR
affiliation: Hacettepe University
name: Melda Saglam, PhD
role: STUDY_CHAIR
affiliation: Hacettepe University
name: Ebru Calik-Kütükcü, PhD
role: STUDY_CHAIR
affiliation: Hacettepe University
name: Hulya Arikan, Professor
role: STUDY_CHAIR
affiliation: Hacettepe University
name: Saadettin Kilickap, Professor
role: STUDY_CHAIR
References: