Clinical trial NCT00131781: Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder
Official title: Cognitive Therapy Versus Supportive Therapy in Borderline Personality Disorder
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Borderline Personality Disorder
Keywords: Borderline personality disorder
Controlled trials
Cognitive Therapy
Supportive Therapy
suicide
impulsivity
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2005-08-19
Enrollment: 70
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Allocation: RANDOMIZED
Intervention model: PARALLEL

Brief summary: This is a randomised trial comparing cognitive therapy and supportive therapy administered along one year in borderline personality disorder. The follow-up is one year after treatments end.

The therapists were the same in the two groups. Patients received one session a week during six months and one session every two weeks during the next six months

Detailed description: * Cognitive Therapy
* Structured session
* Conceptualization of the case with the patient
* Cognitive methods
* Guided discovery of the schemas
* Work on life-scenarios
* From scenarios to schemas
* Empathic confrontation to the schemas
* Building new schemas (Core belief work-sheet)
* Affective methods: role playing
* Interpersonal methods: counter transference issues
* Behavioral experiment
* Problem solving
* Consolidation methods
* Patients and therapists had manuals
* Supportive Therapy
* Therapist: active listening (face to face)
* Empathy
* Unconditional positive regard
* Reformulation and clarification
* Reflection of the patient's feelings
* Reassurance
* Therapist emphasizes the importance to ventilate problems
* Therapist answers some factual questions
* Therapist politely ignore or refuse requests for advice and directive attitudes
* Therapist demonstrates warmth and genuineness
* Patients and therapists had manuals

Eligibility criteria: Inclusion Criteria:

* DSM-4 DIBR \>=8 (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Diagnostic inventory for borderline-revised)

Primary outcomes:
measure: Clinical Global Impression (CGI): Improvement (1-7): score 3 ( a little better) associated with a hopelessness scale score < 8 (this means that the suicide risk is low)
Secondary outcomes:
measure: CGI severity and improvement
measure: Hamilton depression
measure: Beck Depression Inventory
measure: Hopelessness
measure: Young: Schema Questionnaire II
measure: Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Personality Disorders Personality Questionnaire (SCID II PQ)
measure: Minnesota Multiphasic Personality Inventory (MMPI) (minimult)
measure: Eysenck: impulsivity scale
measure: Checklist: impulsive risky behaviors
measure: Quality of life
measure: Handicap (Sheehan)
measure: Time: Pre test, six months, post test and one year post treatment follow-up
measure: Therapeutic relationship evaluation scale (patients and therapists)
Other outcomes:
Locations:
city: Bron
country: France
facility: Hopital Pierre Wertheimer
Study officials:
affiliation: Hospices Civils de Lyon
name: Jean COTTRAUX, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Storebo OJ, Stoffers-Winterling JM, Vollm BA, Kongerslev MT, Mattivi JT, Jorgensen MS, Faltinsen E, Todorovac A, Sales CP, Callesen HE, Lieb K, Simonsen E. Psychological therapies for people with borderline personality disorder. Cochrane Database Syst Rev. 2020 May 4;5(5):CD012955. doi: 10.1002/14651858.CD012955.pub2.