Clinical trial NCT04698746: PENG vs Intra-articular Injection for Hip Arthroscopy
Official title: Pericapsular Nerve Group (PENG) Block Versus Intra-articular Injection for Hip Arthroscopy: A Randomized Trial
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Opioid Use
Acute Pain
Keywords: Hip arthroscopy, intra-articular injection, PENG block
Lead sponsor: Bezmialem Vakif University
Sponsor class: OTHER
First posted: 2021-01-07
Enrollment: 72
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Hip arthroscopy is a popular surgical method that is increasingly being used for both intraarticular and extraarticular hip surgeries. Postoperative acute pain is difficult to control in hip surgeries due to the complex nature of hip innervation and the large number of surgical interventions. Optimal treatment of postoperative pain in hip arthroscopy is very important to be able to perform rehabilitation, avoid opioid side effects and minimize unplanned re-hospitalization. Regional anesthesia techniques are widely used because of their proven efficacy in post-surgical pain management and their safety profile that ultimately contributes to early recovery. Many regional techniques such as neuraxial blocks, lumbar plexus block, femoral nerve block, fascia iliac block and intraarticular local anesthetic injection have been used for the treatment of acute postoperative pain.

Femoral nerve and fascia iliac blocks have shown good results for long-term post-surgery analgesia. However, the obturator nerve and accessory obturator nerve should be targeted to achieve more effective perioperative pain control. There are studies reporting that pericapsular nerve group block (PENG), which has been defined in recent years, provides effective perioperative analgesia in hip surgeries. In this study, we aim to compare the effectiveness of PENG block and intra-articular local anesthetic injection in hip arthroscopy.


Eligibility criteria: Inclusion Criteria:

* American Association of Anesthesiologists (ASA) physical status I - III
* BMI 20 to 35 kg / m2
* Patients scheduled for elective hip arthroscopy
* Able to provide informed consent.

Exclusion Criteria:

* Patients who refuse to participate in the study,
* Coagulopathy,
* Sepsis,
* Hepatic or renal insufficiency,
* Pregnancy
* Allergy to local anesthetic drugs,
* Chronic pain condition requiring opioid intake at home,
* BMI above 40.
* History of psychiatric diseases needing treatment.
* Failure of nerve block
* Substance abuse history
* Hip revision surgery
* Underlying neurologic disorder affecting pain perception.
* Angina, heart attack, heart failure
* Kidney or hepatic insufficiency
* Stroke
* Gastrintestinal bleeding history

Primary outcomes:
measure: Postoperative opioid consumption
timeFrame: up to the first 24 hours postoperatively
Secondary outcomes:
measure: Pain intensity score
timeFrame: 0.5, 1, 3, 6, 12, 24 hours postoperatively.
measure: First rescue analgesic time
timeFrame: up to the first 24 hours postoperatively
measure: Postoperative nausea and vomiting
timeFrame: up to the first 24 hours postoperatively
measure: Patient satisfaction
timeFrame: at the end of 24 hours postoperatively
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakıf University
Study officials:
affiliation: Bezmialem Vakif University
name: Yeşiltaş
role: PRINCIPAL_INVESTIGATOR
References: