Clinical trial NCT00603421: Effectiveness of a 24 Hour Phone Line on the Rate of Suicide Attempts in Borderline Patients
Official title: Effectiveness of a 24 Hour Phone Line on the Rate of Suicide Attempts in Borderline Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Borderline Personality Disorder
Keywords: borderline personality disorder
suicide
suicidality
suicide attempt
suicidal behavior
self-injurious behavior
self-harm behavior
suicide prevention center
telephone intervention
Lead sponsor: Assistance Publique - Hôpitaux de Paris
Sponsor class: OTHER
First posted: 2008-01-29
Enrollment: 318
Sex: ALL
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: This randomized multicentric clinical trial assesses the effectiveness of 24 hour phone line on the rate of suicide attempts and self-injurious behaviors in borderline patients.

Detailed description: Borderline personality disorder is very frequent among psychiatric populations, and chronic suicidality is a major problem in clinical practice with borderline patients. In a lot of countries, suicide prevention centers are available, but most of these centers are not supervised by professionals of mental health, and none is specifically oriented to the borderline population.

The main goal of this study is to assess the effectiveness of a 24 hour crisis phone line on the rate of suicide attempts in a clinical population of borderline patients (the effectiveness of this phone line access on the rate of self-injurious behaviours will also be studied).

In this multicentric controlled trial, 600 borderline patients (men or women, in or out-patients, between 18 and 40 years-old) are randomized in two arms :

* one with treatment as usual
* one with treatment as usual, PLUS one year of access to a 24 hour crisis phone line (with a team of psychiatrists specialized in borderline personality disorder).

All patients are assessed with standardized instruments (interviewers are blind to the patient's status), at entry (T1) and one year later (T2).

Eligibility criteria: Inclusion Criteria:

* 18 to 40 years old
* in or out-patient in one of the recruiting center
* men or women
* with a borderline personality disorder
* written informed consent

Exclusion Criteria:

* inferior to 18 or superior to 40 years old
* schizophrenia
* severe somatic disorder
* participation refusal
* participation to another interventional study

Primary outcomes:
measure: Rate of suicide attempts
timeFrame: Annual
Secondary outcomes:
measure: rate of self injurious behaviors
timeFrame: annual
Other outcomes:
Locations:
city: Paris
country: France
facility: Hôpital St Anne
city: Paris
country: France
facility: Hopital Cochin Centre de recherche Clinique Paris Centre
Study officials:
affiliation: Centre Hospitalier Sainte Anne
name: Alexandra Pham-Scottez, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Witt KG, Hetrick SE, Rajaram G, Hazell P, Taylor Salisbury TL, Townsend E, Hawton K. Psychosocial interventions for self-harm in adults. Cochrane Database Syst Rev. 2021 Apr 22;4(4):CD013668. doi: 10.1002/14651858.CD013668.pub2.
citation: Storebo OJ, Stoffers-Winterling JM, Vollm BA, Kongerslev MT, Mattivi JT, Jorgensen MS, Faltinsen E, Todorovac A, Sales CP, Callesen HE, Lieb K, Simonsen E. Psychological therapies for people with borderline personality disorder. Cochrane Database Syst Rev. 2020 May 4;5(5):CD012955. doi: 10.1002/14651858.CD012955.pub2.