Clinical trial NCT06258369: Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis
Official title: Gait Initiation and Transition From Double to Single Support in Patients With Unilateral Primary Coxarthrosis Who Have Not Undergone Surgery and Before/After Arthroplasty
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Primary; Coxarthrosis
Keywords: Coxarthrosis
Hip
Arthroplasty
Gait initiation
Lead sponsor: Lille Catholic University
Sponsor class: OTHER
First posted: 2024-02-14
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Patients with coxarthrosis (any stage) without surgery

Patients with coxarthrosis (any stage) with THP (Total Hip replacement)

Patients with coxarthrosis (any stage) with RHT (Hip resurfacing)
Primary purpose: OTHER

Brief summary: The study consists to evaluate the impact of prosthetic surgery (PTH and RTH) on kinematic and dynamic parameters (joint torques) of the lower limbs during gait initiation in patients with primary coxarthrosis.

Patients included in the study will undergo a three-dimensional gait analysis. Dynamic gait analysis is multidimensional, measuring kinematic parameters (joint amplitudes: ankles, knees, hips, etc.) and dynamic parameters (assessment of joint torque from ankle, knee, hip to lower limb during gait initiation).


Eligibility criteria: Inclusion Criteria:

* Men or women aged 18 and over
* With primary coxarthrosis (any stage)
* Consulting in the orthopedic departments of participating centers in anticipation of hip surgery (PTH/RTH), or for advice only.
* Written consent signed by the patient
* Affiliation with a social security scheme

Exclusion Criteria:

* Disabling orthopaedic conditions:

Symptomatic contralateral hip/knee disease Symptomatic gonarthrosis or homolateral total knee prosthesis History of surgery on the affected hip History of fracture of the lower limb in the past year History of lower limb sprain in the last 3 months Neurological or degenerative disease

* Pregnant or breast-feeding
* Adults under guardianship, curatorship or safeguard of justice
* Cognitive impairment making it impossible to understand the protocol
* Approach other than Moore posterolateral (for PTH and RTH groups)

Primary outcomes:
measure: Amplitude degree of lower limbs articulations
timeFrame: 6 months
measure: Dynamics of limbs joint torques during walking initiation measured in Nm/kg
timeFrame: 6 months
Secondary outcomes:
measure: Step length during gait initiation
timeFrame: 6 months
measure: Step width during gait initiation
timeFrame: 6 months
measure: Duration of first step during gait initiation
timeFrame: 6 months
measure: Duration of anticipatory postural adjustment phase during gait initiation
timeFrame: 6 months
measure: Duration of execution phase during gait initiation
timeFrame: 6 months
measure: Measurement of the trajectory during gait initiation
timeFrame: 6 months
measure: Measurement of the speed during gait initiation
timeFrame: 6 months
measure: Measurement of the amplitude of retreat of the center of pressure during gait initiation
timeFrame: 6 months
measure: Severity of coxarthrosis according to the Tönnis classification
timeFrame: 6 Months
measure: HHS (Harris Hip Score)
timeFrame: 6 months
measure: PMA (Postel Merle d'Aubigné) score
timeFrame: 6 months
measure: Devane score
timeFrame: 6 months
measure: UCLA (University of California Los Angeles) score
timeFrame: 6 months
measure: Vellas unipodal weight-bearing test
timeFrame: 6 months
measure: Pelvic incidence
timeFrame: 6 months
measure: Sacral slope angle
timeFrame: 6 months
measure: Pelvic tilt angle
timeFrame: 6 months
Other outcomes:
Locations:
city: Lille
country: France
facility: CHU de Lille
city: Lomme
country: France
facility: Hôpital Saint-Philibert (GHICL)
Study officials:
affiliation: Hôpital Saint Philibert, GHICL
name: Pierre MARTINOT, MD
role: STUDY_DIRECTOR
References: