Clinical trial NCT02961543: Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Anterior Cruciate Ligament Reconstruction
Official title: Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Anterior Cruciate Ligament Reconstruction
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Anterior Cruciate Ligament Injury
Lead sponsor: Federal University of Health Science of Porto Alegre
Sponsor class: OTHER
First posted: 2016-11-11
Enrollment: 30
Sex: MALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: A randomized clinical trial involving 30 individuals submitted to ACL reconstruction will be conducted.

Participants will be randomized into: Group I, submitted to a muscular rehabilitation program based on eccentric isokinetic exercise; and Group II, submitted to a muscular rehabilitation program based on eccentric isotonic exercise. Concomitantly with the muscular rehabilitation protocols, individuals will undergo the same physiotherapeutic protocol with analgesia, edema reduction, range of motion, proprioception and functionality goals. Muscle rehabilitation programs based on eccentric isotonic and isokinetic exercise will begin 45 days after ACL reconstruction. The programs will last six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.


Eligibility criteria: Inclusion Criteria:

* Young adults aged between 18 and 40 years;
* Recreational athletes;
* Unilateral ACL injury;
* Presence of total or partial rupture of unilateral ACL within 90 days after injury;
* Male subjects;
* Classification of body mass index up to pre-obese (25.0 - 29.9 kg / m2);
* Not undergoing any strength training program for the lower limbs in the six months prior to the study.
* Acceptance of individuals in participating in the procedures proposed by the research.

Exclusion Criteria:

* Recidivism in ligament injuries;
* Associated ligament and / or meniscal lesions;
* Previous history (\<6 months) of musculoskeletal lesions in the thigh;
* Patellar tendinopathy;
* Patellofemoral pain syndrome;
* Respiratory or cardiovascular conditions that limit the performance of exercises;
* Users of dietary supplements or anabolic steroids

Primary outcomes:
measure: The femoral quadriceps muscle mass through nuclear magnetic resonance imaging
timeFrame: Change from baseline and six weeks after intervention protocol
Secondary outcomes:
measure: Performance of knee extensors through computerized dynamometry
timeFrame: Change from baseline and six weeks after intervention protocol
measure: Functionality of the individuals through Lysholm score
timeFrame: Change from baseline and six weeks after intervention protocol
measure: Functionality of the individuals through single and triple hop test
timeFrame: Change from baseline and six weeks after intervention protocol
Other outcomes:
Locations:
city: Porto Alegre
country: Brazil
facility: Universidade Federal de Ciências da Saúde de Porto Alegre
state: RS
Study officials:
affiliation: Federal University of Health Science of Porto Alegre
name: Marlon F Vidmar, MSc
role: PRINCIPAL_INVESTIGATOR
References: