Clinical trial NCT05471284: Recruitment Messages for Current Smokers Recently Diagnosed With Cancer
Official title: A Multimethod Evaluation of Tobacco Treatment Trial Recruitment Messages for Current Smokers Recently Diagnosed With Cancer: Pilot Factorial Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Tobacco Smoking
Health Behavior
Keywords: Cancer
Digital outreach
Multimethod randomized trial
Factorial Design
Message Frames
Tobacco use
Smoker enrollment rates
Lead sponsor: University of Oklahoma
Sponsor class: OTHER
Collaborators: name: Tufts University
name: Massachusetts General Hospital
name: Memorial Sloan Kettering Cancer Center
First posted: 2022-07-22
Enrollment: 99
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The objective of this study was to conduct a pilot factorial randomized trial to identify the message frames that are most effective in promoting participation in a tobacco treatment trial for current smokers recently diagnosed with cancer. To do so, we used a multimethod approach to evaluate 3 different message frames across evaluation, effectiveness, and outcome measures. We combine findings from a message design experiment with textual analytic software to provide a holistic understanding of how message frames may or may not differentially affect tobacco treatment trial participation within the context of a cancer diagnosis.

Detailed description: Background: A cancer diagnosis can catalyze motivation to quit smoking. Tobacco treatment trials offer cessation resources but have low accrual rates. Digital outreach may improve accrual, but knowledge of how best to recruit smokers with recent diagnoses is limited.

Objective: This study aims to identify the message frames that were most effective in promoting intent to talk to a physician about participating in a tobacco treatment trial for smokers recently diagnosed with cancer.

Methods: From February to April 2019, current smokers diagnosed within the past 24 months were recruited from a national web-based panel for a multimethod pilot randomized trial (N=99). Participants were randomized to a 2×3 plus control factorial design that tested 3 unique message frames: proximal versus distal threats of smoking, costs of continued smoking versus benefits of quitting, and gains of participating versus losses of not participating in a tobacco treatment trial.

Eligibility criteria: Inclusion Criteria:

* Speak and understand English
* A recent cancer diagnosis (within the past 24 months)
* 18 years or older
* Report any cigarette use within the past 30 days

Exclusion Criteria:

* Do not speak or understand English
* Have not been diagnosed with cancer within the past 24 months
* Below the age of 18
* Does not report any cigarette use within the past 30 days

Primary outcomes:
measure: Difference in intent to talk to a physician about participating in a smoking cessation study between factors.
timeFrame: Within 30 minutes
Secondary outcomes:
measure: Predictors of intent to talk to a physician about participating in a smoking cessation study.
timeFrame: Within 30 minutes
Other outcomes:
Locations:
city: Oklahoma City
country: United States
facility: Jordan Neil
state: Oklahoma
Study officials:
affiliation: TSET Health Promotion Research Center
name: Jordan Neil, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Neil JM, Senecal C, Ballini L, Chang Y, Goshe B, Flores E, Ostroff JS, Park ER. A Multimethod Evaluation of Tobacco Treatment Trial Recruitment Messages for Current Smokers Recently Diagnosed With Cancer: Pilot Factorial Randomized Controlled Trial. JMIR Cancer. 2022 Aug 24;8(3):e37526. doi: 10.2196/37526.