Clinical trial NCT03006068: A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
Official title: A Phase 3 Multicenter, Long-Term Extension Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) in Subjects With Ulcerative Colitis
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: PHASE3
Conditions: Ulcerative Colitis (UC)
Keywords: Ulcerative Colitis (UC)
Upadacitinib (ABT-494)
Long Term Extension (LTE)
Safety
Efficacy
RINVOQ
Lead sponsor: AbbVie
Sponsor class: INDUSTRY
First posted: 2016-12-30
Enrollment: 950
Sex: ALL
Minimum age (years): 16
Maximum age (years): 75
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study is designed to evaluate the long-term safety and efficacy of Upadacitinib in participants with ulcerative colitis (UC) who have not responded at the end of the induction period in Study M14-234 Substudy 1, who have had loss of response during the maintenance period of Study M14-234 Substudy 3, or who have successfully completed Study M14-234 Substudy 3.


Eligibility criteria: Inclusion Criteria:

Note: Participants aged 16 or 17 may enroll in M14-234 or M14-675 where locally permissible

* Participant has not achieved clinical response at the end of the induction period (Week 8) in Study M14-234 Substudy 1, has had loss of response during the maintenance period of Study M14-234 Substudy 3, or has successfully completed Study M14-234 Substudy 3. During the COVID-19 pandemic, for participants with missing endoscopy at Week 8, Week 16 or Week 52 due to the COVID-19 pandemic in Studies M14-234 Substudy 2, M14-234 Substudy 3 and M14-675, participants may be enrolled if certain criteria are met.
* If female, participant must meet the contraception criteria.
* Women of childbearing potential must have a negative urine pregnancy test at Week 0 visit.
* Participant is judged to be in otherwise good health as determined by the principal investigator based upon clinical evaluations performed during the preceding study (Study M14-234).
* Must be able and willing to give written informed consent and to comply with the requirements of this study protocol.

Exclusion Criteria:

* For any reason participant is considered by the investigator to be an unsuitable candidate.
* Female participant with a positive pregnancy test at the final visit of Study M14-234 or who is considering becoming pregnant during the study or within 30 days after the last dose of study drug.
* Known hypersensitivity to upadacitinib or its excipients or had any adverse event (AE) during the preceding studies, that in the investigator's judgment makes the participant unsuitable for this study.
* Participant with an active or recurrent infection that based on the investigator's clinical assessment makes the participant an unsuitable candidate for the study. Participants with ongoing infections undergoing treatment may be enrolled BUT NOT dosed until the infection has been successfully treated.
* Current evidence of active tuberculosis (TB); current evidence of latent tuberculosis and for any reason the participant cannot take full course of TB prophylaxis treatment as required per protocol.
* Participant with a poorly controlled medical condition, such as uncontrolled diabetes, unstable ischemic heart disease, moderate or severe congestive heart failure (New York Heart Association class III or IV), recent cerebrovascular accidents and any other condition which, in the opinion of the investigator or sponsor, would put the subject at risk by participation in this study.
* Participants have malignancy, high-grade dysplasia, un-removed low-grade dysplasia of the gastrointestinal tract diagnosed at the endoscopy performed at the final visit of Study M14-234.
* History of any malignancy except for successfully treated nonmelanoma skin cancer (NMSC) or localized carcinoma in situ of the cervix from evaluations performed in Study M14-234.

Primary outcomes:
measure: Assessing Treatment-Emergent Adverse Events
timeFrame: Up to 288 Weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Mobile
country: United States
facility: East View Medical Research, LLC /ID# 171184
state: Alabama
city: Mobile
country: United States
facility: CB Flock Research Corporation /ID# 165986
state: Alabama
city: Chandler
country: United States
facility: Delsol Research Management, Ll /Id# 170130
state: Arizona
city: Mesa
country: United States
facility: Digestive Disease Consultants, A Division of Arizona Digestive Health, P.C /ID# 211886
state: Arizona
city: Sun City
country: United States
facility: Arizona Arthritis & Rheumatology Research, PLLC /ID# 169823
state: Arizona
city: Tucson
country: United States
facility: Adobe Clinical Research LLC /ID# 155249
state: Arizona
city: Tucson
country: United States
facility: University of Arizona /ID# 150568
state: Arizona
city: Covina
country: United States
facility: Citrus Valley Gastroenterology /ID# 151915
state: California
city: Huntington Beach
country: United States
facility: Newport Huntington Medical Group /ID# 217006
state: California
city: La Jolla
country: United States
facility: UC San Diego Health System /ID# 155187
state: California
city: Los Alamitos
country: United States
facility: United Medical Doctors /ID# 207467
state: California
city: Los Angeles
country: United States
facility: TLC Clinical Research Inc /ID# 216830
state: California
city: Los Angeles
country: United States
facility: Gastrointestinal Biosciences Clinical Trials, LLC /ID# 157082
state: California
city: Mission Hills
country: United States
facility: Facey Medical Foundation /ID# 203135
state: California
city: Murrieta
country: United States
facility: United Medical Doctors - Murrieta /ID# 151213
state: California
city: Oxnard
country: United States
facility: Ventura County Gastroenterology Medical Group /ID# 163417
state: California
city: Rialto
country: United States
facility: Inland Empire Clinical Trials, LLC /ID# 216163
state: California
city: San Diego
country: United States
facility: San Diego Clinical Trials /ID# 212121
state: California
city: San Diego
country: United States
facility: Medical Assoc Research Grp /ID# 169149
state: California
city: San Francisco
country: United States
facility: Univ of California San Francis /ID# 164583
state: California
city: Colorado Springs
country: United States
facility: Delta Waves, Inc. /ID# 151727
state: Colorado
city: Lone Tree
country: United States
facility: South Denver Gastroenterology /ID# 151224
state: Colorado
city: Wheat Ridge
country: United States
facility: Western States Clinical Res /ID# 158078
state: Colorado
city: Danbury
country: United States
facility: Duplicate_Western Connecticut Medical Group /ID# 169211
state: Connecticut
city: Hamden
country: United States
facility: Gastroenterology Center of Connecticut /ID# 150534
state: Connecticut
city: Clearwater
country: United States
facility: West Central Gastroenterology /ID# 155242
state: Florida
city: Doral
country: United States
facility: Moonshine Research Center, Inc /ID# 152534
state: Florida
city: Doral
country: United States
facility: Universal Axon Clinical Research /ID# 213463
state: Florida
city: Hialeah
country: United States
facility: Palmetto Research, LLC /ID# 151724
state: Florida
city: Inverness
country: United States
facility: Nature Coast Clinical Research - Inverness /ID# 154070
state: Florida
city: Jacksonville
country: United States
facility: Encore Borland-Groover Clinical Research /Id# 170913
state: Florida
city: Kissimmee
country: United States
facility: SIH Research Mumtaz, Inc /ID# 163199
state: Florida
city: Maitland
country: United States
facility: Cfagi Llc /Id# 202018
state: Florida
city: Miami
country: United States
facility: University of Miami /ID# 215443
state: Florida
city: Miami
country: United States
facility: Advanced Pharma CR, LLC /ID# 151723
state: Florida
city: Miami
country: United States
facility: New Horizon Research Center /ID# 152475
state: Florida
city: Miami
country: United States
facility: Crystal Pharmacology Research /ID# 151848
state: Florida
city: Miami
country: United States
facility: Coral Research Clinic /ID# 150524
state: Florida
city: New Port Richey
country: United States
facility: Advanced Research Institute, Inc /ID# 163093
state: Florida
city: Orlando
country: United States
facility: Endoscopic Research, Inc. /ID# 151725
state: Florida
city: Orlando
country: United States
facility: Omega Research Group /ID# 200271
state: Florida
city: Tampa
country: United States
facility: Clinical Research Trials of Florida, Inc. /ID# 201791
state: Florida
city: Tampa
country: United States
facility: Duplicate_University of South Florida /ID# 214494
state: Florida
city: Tampa
country: United States
facility: Duplicate_AdventHealth Tampa /ID# 200274
state: Florida
city: Macon
country: United States
facility: Gastroenterology Associates of Central Georgia, LLC /ID# 165783
state: Georgia
city: Riverdale
country: United States
facility: Infinite Clinical Trials /ID# 215342
state: Georgia
city: Suwanee
country: United States
facility: Atlanta Gastroenterology Spec /ID# 150565
state: Georgia
city: Chicago
country: United States
facility: Next Innovative Clinical Research - Chicago /ID# 217323
state: Illinois
city: Chicago
country: United States
facility: The University of Chicago DCAM /ID# 150564
state: Illinois
city: Evanston
country: United States
facility: NorthShore University HealthSystem /ID# 150570
state: Illinois
city: Hoffman Estates
country: United States
facility: Northwest Health Care Associates /ID# 151591
state: Illinois
city: Urbana
country: United States
facility: Carle Foundation Hospital /ID# 151155
state: Illinois
city: Evansville
country: United States
facility: MediSphere Medical Research Center /ID# 152080
state: Indiana
city: Indianapolis
country: United States
facility: Indianapolis Gastroenterology /ID# 162914
state: Indiana
city: Iowa City
country: United States
facility: University of Iowa Hospitals and Clinics /ID# 157059
state: Iowa
city: Topeka
country: United States
facility: Cotton O'Neil Clinical Research Center, Digestive Health /ID# 167183
state: Kansas
city: Crestview Hills
country: United States
facility: Tri-State Gastroenterology /ID# 169812
state: Kentucky
city: Houma
country: United States
facility: Houma Digestive Health Special /ID# 151851
state: Louisiana
city: New Orleans
country: United States
facility: Nola Research Works, LLC /ID# 153365
state: Louisiana
city: Shreveport
country: United States
facility: Louisiana Research Center, LLC /ID# 150526
state: Louisiana
city: Baltimore
country: United States
facility: University of Maryland, Baltimore /ID# 150529
state: Maryland
city: Columbia
country: United States
facility: Gastro Center of Maryland /ID# 200024
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital /ID# 165678
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 151158
state: Michigan
city: Ann Arbor
country: United States
facility: Huron Gastroenterology Assoc /ID# 152712
state: Michigan
city: Chesterfield
country: United States
facility: Clin Res Inst of Michigan, LLC /ID# 153031
state: Michigan
city: Chesterfield
country: United States
facility: Clin Res Inst of Michigan, LLC /ID# 161983
state: Michigan
city: Southfield
country: United States
facility: Revival Research Institute, LLC /ID# 207281
state: Michigan
city: Wyoming
country: United States
facility: Gastroenterology Associates of Western Michigan, PLC d.b.a. West Michigan Clinic /ID# 157487
state: Michigan
city: Rochester
country: United States
facility: Mayo Clinic - Rochester /ID# 151681
state: Minnesota
city: Saint Paul
country: United States
facility: Minnesota Gastroenterology PA /ID# 151682
state: Minnesota
city: Jackson
country: United States
facility: University of Mississippi Medical Center /ID# 213140
state: Mississippi
city: Jackson
country: United States
facility: Southern Therapy and Advanced Research (STAR) LLC /ID# 170713
state: Mississippi
city: Saint Louis
country: United States
facility: Washington University-School of Medicine /ID# 150537
state: Missouri
city: Las Vegas
country: United States
facility: Vector Clinical Trials /ID# 153052
state: Nevada
city: Lebanon
country: United States
facility: Dartmouth-Hitchcock Medical Center - 1 Medical Center Drive /ID# 150566
state: New Hampshire
city: Egg Harbor Township
country: United States
facility: Cooper Gastroenterology at Fire Road /ID# 153048
state: New Jersey
city: Morristown
country: United States
facility: Atlantic Digestive Health Inst /ID# 150527
state: New Jersey
city: New Brunswick
country: United States
facility: Rutgers Robert Wood Johnson /ID# 155247
state: New Jersey
city: Albuquerque
country: United States
facility: Duplicate_University of New Mexico Department of Internal Medicine /ID# 214399
state: New Mexico
city: Bronx
country: United States
facility: Montefiore Medical Center - Moses Campus /ID# 150559
state: New York
city: Bronx
country: United States
facility: Advantage Clinical Trials /ID# 163940
state: New York
city: Brooklyn
country: United States
facility: NY Scientific /ID# 152708
state: New York
city: Great Neck
country: United States
facility: NYU Langone Long Island Clinical Research Association /ID# 155271
state: New York
city: New York
country: United States
facility: Columbia Univ Medical Center /ID# 163409
state: New York
city: North Massapequa
country: United States
facility: Duplicate_DiGiovanna Institute for Medical Education & Research /ID# 201534
state: New York
city: Poughkeepsie
country: United States
facility: Premier Medical Group - GI Division /ID# 153366
state: New York
city: Rochester
country: United States
facility: Gastoenterology Group of Rochester /ID# 151080
state: New York
city: Staten Island
country: United States
facility: Richmond University Medical Center /ID# 201860
state: New York
city: Asheville
country: United States
facility: Digestive Health Partners - Biltmore Office /ID# 167238
state: North Carolina
city: Charlotte
country: United States
facility: Atrium Health Carolinas Medical Center /ID# 157060
state: North Carolina
city: Charlotte
country: United States
facility: Charlotte Gastroenterology and Hepatology, PLLC /ID# 150561
state: North Carolina
city: Greenville
country: United States
facility: Atlantic Gastroenterology Clinical Research /ID# 151901
state: North Carolina
city: Winston-Salem
country: United States
facility: Clinical Trials of America /ID# 153453
state: North Carolina
city: Winston-Salem
country: United States
facility: Atrium Health Wake Forest Baptist Medical Center /ID# 150528
state: North Carolina
city: Fargo
country: United States
facility: Plains Clinical Research Center, LLC /ID# 170291
state: North Dakota
city: Cincinnati
country: United States
facility: Gastro Health Research /ID# 151683
state: Ohio
city: Cincinnati
country: United States
facility: University Of Cincinnati Medical Center /ID# 164584
state: Ohio
city: Columbus
country: United States
facility: The Ohio State University /ID# 169417
state: Ohio
city: Columbus
country: United States
facility: Optimed Research, Ltd. /ID# 169697
state: Ohio
city: Dayton
country: United States
facility: Hometown Urgent Care and Resea /ID# 200066
state: Ohio
city: Englewood
country: United States
facility: Dayton Gastroenterology, Inc. /ID# 167632
state: Ohio
city: Mentor
country: United States
facility: Great Lakes Gastroenterology Research, LLC /ID# 201773
state: Ohio
city: Mentor
country: United States
facility: Ohio Clinical Research Partner /ID# 154074
state: Ohio
city: Oklahoma City
country: United States
facility: Hightower Clinical /ID# 216338
state: Oklahoma
city: Oklahoma City
country: United States
facility: Digestive Disease Specialists /ID# 201057
state: Oklahoma
city: Tulsa
country: United States
facility: Options Health Research, LLC /ID# 150569
state: Oklahoma
city: Tulsa
country: United States
facility: Healthcare Research Consultant /ID# 163096
state: Oklahoma
city: Portland
country: United States
facility: Northwest Gastroenterology Clinic /ID# 152528
state: Oregon
city: Sayre
country: United States
facility: Guthrie Medical Group, PC /ID# 150533
state: Pennsylvania
city: State College
country: United States
facility: Penn State Health Colonnade /ID# 150267
state: Pennsylvania
city: Charleston
country: United States
facility: Pharmacorp Clinical Trials /ID# 153363
state: South Carolina
city: Greenville
country: United States
facility: Gastroenterology Associates, P.A. of Greenville /ID# 150557
state: South Carolina
city: Cordova
country: United States
facility: Gastro One /ID# 151154
state: Tennessee
city: Johnson City
country: United States
facility: Duplicate_East Tennessee Research Institute /ID# 203611
state: Tennessee
city: Nashville
country: United States
facility: Quality Medical Research /ID# 203427
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt University Medical Center /ID# 153364
state: Tennessee
city: Arlington
country: United States
facility: TX Clinical Research Institute /ID# 151528
state: Texas
city: Baytown
country: United States
facility: Inquest Clinical Research /ID# 164636
state: Texas
city: Cedar Park
country: United States
facility: Texas Digestive Disease Consultants /ID# 209949
state: Texas
city: Cedar Park
country: United States
facility: GI Alliance /ID# 209806
state: Texas
city: Dallas
country: United States
facility: Baylor Scott & White Center for Inflammatory Bowel Diseases /ID# 200771
state: Texas
city: Garland
country: United States
facility: Digestive Health Associates of Texas (DHAT) Research Institute - Garland /ID# 151221
state: Texas
city: Houston
country: United States
facility: Vilo Research Group Inc /ID# 212626
state: Texas
city: Houston
country: United States
facility: CliniCore International, LLC /ID# 152078
state: Texas
city: Houston
country: United States
facility: Duplicate_Baylor College of Medicine - Baylor Medical Center /ID# 150538
state: Texas
city: Houston
country: United States
facility: Centex Studies, Inc. - Houston /ID# 201217
state: Texas
city: Houston
country: United States
facility: GI Specialists of Houston /ID# 202337
state: Texas
city: Lubbock
country: United States
facility: Duplicate_Caprock Gastro Research, LLC /ID# 215116
state: Texas
city: San Antonio
country: United States
facility: Clinical Associates in Research Therapeutics of America, LLC /ID# 167954
state: Texas
city: San Antonio
country: United States
facility: Southern Star Research Institute, LLC /ID# 169397
state: Texas
city: Sugar Land
country: United States
facility: Carl R. Meisner Medical Clinic /ID# 171270
state: Texas
city: Temple
country: United States
facility: Baylor Scott & White Center for Diagnostic Medicine /ID# 204777
state: Texas
city: Tyler
country: United States
facility: Tyler Research Institute, LLC /ID# 169147
state: Texas
city: Victoria
country: United States
facility: Gastro Health & Nutrition - Victoria /ID# 167764
state: Texas
city: Bountiful
country: United States
facility: HP Clinical Research /ID# 163941
state: Utah
city: Ogden
country: United States
facility: Advanced Research Institute /ID# 162640
state: Utah
city: Salt Lake City
country: United States
facility: Utah Gastroenternology - St. Mark's Office /ID# 163097
state: Utah
city: West Jordan
country: United States
facility: Velocity Clinical Research - Salt Lake City /ID# 163180
state: Utah
city: Franklin
country: United States
facility: Ctr for Gastrointestinal Healt /ID# 153369
state: Virginia
city: Bellevue
country: United States
facility: Texas Digestive Disease Consultants, PLLC dba GI Alliance /ID# 163630
state: Washington
city: Seattle
country: United States
facility: Virginia Mason Hospital & Medical Center /ID# 153030
state: Washington
city: Seattle
country: United States
facility: The Polyclinic /ID# 165117
state: Washington
city: Vancouver
country: United States
facility: The Vancouver Clinic, INC. PS /ID# 162334
state: Washington
city: Grafton
country: United States
facility: Aurora Medical Center - Grafto /ID# 151726
state: Wisconsin
city: Milwaukee
country: United States
facility: Wisconsin Center for Advanced Research /ID# 151845
state: Wisconsin
city: Milwaukee
country: United States
facility: Duplicate_Medical College of Wisconsin /ID# 151850
state: Wisconsin
city: San Isidro
country: Argentina
facility: Cardio Alem /ID# 211281
state: Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Gedyt /ID# 210016
state: Ciudad Autonoma De Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Mautalen Salud e Investigacion /ID# 171174
state: Ciudad Autonoma De Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Hospital Britanico de Buenos Aires /ID# 209496
state: Ciudad Autonoma De Buenos Aires
city: San Miguel de Tucumán
country: Argentina
facility: Sanatorio 9 de Julio /ID# 150215
state: Tucuman
city: Cordoba
country: Argentina
facility: Hospital Privado Universitario - Hospital Privado Centro Medico de Cordoba S.A. /ID# 164186
city: Macquarie University
country: Australia
facility: Macquarie University Hospital /ID# 211953
state: New South Wales
city: South Brisbane
country: Australia
facility: Mater Misericordiae Limited /ID# 212686
state: Queensland
city: Southport
country: Australia
facility: Griffith University /ID# 211954
state: Queensland
city: Clayton
country: Australia
facility: Monash Health - Monash Medical Centre /ID# 150218
state: Victoria
city: Fitzroy Melbourne
country: Australia
facility: St Vincent's Hospital Melbourne /ID# 152503
state: Victoria
city: Murdoch
country: Australia
facility: Fiona Stanley Hospital /ID# 211641
state: Western Australia
city: Linz
country: Austria
facility: Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 150462
state: Oberoesterreich
city: Vienna
country: Austria
facility: Klinik Landstrasse /ID# 162867
state: Wien
city: Vienna
country: Austria
facility: Medizinische Universitaet Wien /ID# 150616
state: Wien
city: Salzburg
country: Austria
facility: Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 150463
city: Витебск
country: Belarus
facility: Vitebsk Regional Advanced Clin /ID# 169592
city: Leuven
country: Belgium
facility: Universitair Ziekenhuis Leuven /ID# 150468
state: Vlaams-Brabant
city: Roeselare
country: Belgium
facility: AZ-Delta /ID# 150467
state: West-Vlaanderen
city: Gent
country: Belgium
facility: AZ Maria Middelares /ID# 150466
city: Banja Luka
country: Bosnia and Herzegovina
facility: Duplicate_University Clinical Centre of the Republic of Srpska /ID# 150223
state: Republika Srpska
city: Banja Luka
country: Bosnia and Herzegovina
facility: Duplicate_University Clinical Centre of the Republic of Srpska /ID# 150712
state: Republika Srpska
city: Tuzla
country: Bosnia and Herzegovina
facility: University Clinical Center Tuzla /ID# 150224
state: Tuzlanski
city: Mostar
country: Bosnia and Herzegovina
facility: University Clinical Hospital Mostar /ID# 150711
city: Sarajevo
country: Bosnia and Herzegovina
facility: Clinical Center University of Sarajevo /ID# 150222
city: Goiânia
country: Brazil
facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 153744
state: Goias
city: Santo André
country: Brazil
facility: Faculdade de Medicina do ABC /ID# 152489
state: La Spezia
city: Curitiba
country: Brazil
facility: Hospital Nossa Senhora das Graças /ID# 152488
state: Parana
city: Porto Alegre
country: Brazil
facility: Hospital de Clinicas de Porto Alegre /ID# 153745
state: Rio Grande Do Sul
city: Botucatu
country: Brazil
facility: Upeclin Fmb - Unesp /Id# 152493
state: Sao Paulo
city: Ribeirão Preto
country: Brazil
facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto /ID# 152492
state: Sao Paulo
city: Sao Jose Do Rio Preto
country: Brazil
facility: Kaiser Clinica e Hospital Dia /ID# 152491
state: Sao Paulo
city: Calgary
country: Canada
facility: University of Calgary /ID# 151818
state: Alberta
city: Edmonton
country: Canada
facility: Allen Whey Khye Lim Professional Corporation /ID# 211169
state: Alberta
city: Edmonton
country: Canada
facility: University of Alberta Hospital /ID# 151824
state: Alberta
city: Edmonton
country: Canada
facility: Covenant Health /ID# 158931
state: Alberta
city: Kelowna
country: Canada
facility: OCT Research ULC /ID# 153179
state: British Columbia
city: Victoria
country: Canada
facility: Percuro Clinical Research, Ltd /ID# 150479
state: British Columbia
city: Hamilton
country: Canada
facility: Hamilton Health Sciences - McMaster University Medical Centre /ID# 150477
state: Ontario
city: Ottawa
country: Canada
facility: Ottawa Hospital Research Institute /ID# 151817
state: Ontario
city: Sudbury
country: Canada
facility: Medicor Research Inc /ID# 151825
state: Ontario
city: Vaughan
country: Canada
facility: Toronto Digestive Disease Associates /ID# 150475
state: Ontario
city: Greenfield Park
country: Canada
facility: CISSS de la Monteregie /ID# 159271
state: Quebec
city: Levis
country: Canada
facility: Duplicate_CISSS de Chaudière-Appalaches, Hôpital Hotel-Dieu de Lévis /ID# 150473
state: Quebec
city: Montreal
country: Canada
facility: Recherche GCP Research /ID# 151819
state: Quebec
city: Montreal
country: Canada
facility: Centre Hospitalier de l'Universite de Montreal - CRCHUM /ID# 167170
state: Quebec
city: Montréal
country: Canada
facility: Montreal General Hospital - McGill University Health Centre /ID# 170013
state: Quebec
city: Sherbrooke
country: Canada
facility: CIUSSS de l'Estrie - CHUS /ID# 150478
state: Quebec
city: Concepción
country: Chile
facility: Hospital Guillermo Grant Benavente de Concepción /ID# 212425
state: Bio-Bio
city: Santiago
country: Chile
facility: Research Group /ID# 203177
state: Region Metropolitana De Santiago
city: Providencia
country: Chile
facility: CTR Estudios Clinicos /ID# 200111
state: Region Metropolitana Santiago
city: Santiago
country: Chile
facility: M y F Estudios Clínicos /ID# 200112
state: Region Metropolitana Santiago
city: Viña del Mar
country: Chile
facility: Centro de Investigaciones Clínicas Viña del Mar /ID# 150226
state: Valparaíso
city: Santiago
country: Chile
facility: Hospital Clinico Universidad De Los Andes /ID# 207427
city: Guangzhou
country: China
facility: The First Affiliated Hospital, Sun Yat-sen University /ID# 150517
state: Guangdong
city: Guangzhou
country: China
facility: The Sixth Affiliated Hospital of Sun Yat-sen University /ID# 150518
state: Guangdong
city: Shiyan
country: China
facility: Affiliated Taihe Hospital of Hubei University of Medicine /ID# 216407
state: Hubei
city: Wuhan
country: China
facility: Tongji Hospital Tongji Medical College Huazhong University of Science and Techno /ID# 167089
state: Hubei
city: Wuhan
country: China
facility: Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 167079
state: Hubei
city: Changsha
country: China
facility: Xiangya Hospital Central South University /ID# 167230
state: Hunan
city: Nanchang
country: China
facility: The First Affiliated Hospital of Nanchang University /ID# 212185
state: Jiangxi
city: Changchun
country: China
facility: The First Hospital of Jilin University /ID# 210087
state: Jilin
city: Shenyang
country: China
facility: Shengjing Hospital of China Medical University /ID# 166921
state: Liaoning
city: Shanghai
country: China
facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 150523
state: Shanghai
city: Shanghai
country: China
facility: Shanghai Tenth People's Hospital /ID# 150522
state: Shanghai
city: Shanghai
country: China
facility: Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 165826
state: Shanghai
city: Chengdu
country: China
facility: West China Hospital, Sichuan University /ID# 167041
state: Sichuan
city: Tianjin
country: China
facility: Tianjin Medical University General Hospital /ID# 170605
state: Tianjin
city: Hangzhou
country: China
facility: The second affiliated hospital of Zhejiang University school of medicine /ID# 165813
state: Zhejiang
city: Hangzhou
country: China
facility: Sir Run Run Shaw Hospital,Meical School Zhejiang University /ID# 150516
state: Zhejiang
city: Medellin
country: Colombia
facility: Hospital Universitario de San /ID# 155388
state: Antioquia
city: Monteria
country: Colombia
facility: Oncomedica SAS /ID# 207052
state: Cordoba
city: Bogota DC
country: Colombia
facility: Coorp Hosp Juan Ciudad Sede Hospital Universitario Mayor Mederi /ID# 152811
state: Cundinamarca
city: Zagreb
country: Croatia
facility: Klinicka bolnica Dubrava Zagreb /ID# 150228
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Klinicki bolnicki centar Zagreb /ID# 150262
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Klinicki bolnicki centar Zagreb /ID# 150715
state: Grad Zagreb
city: Osijek
country: Croatia
facility: Duplicate_Klinicki bolnicki centar Osijek /ID# 150229
state: Osjecko-baranjska Zupanija
city: Rijeka
country: Croatia
facility: Klinicki bolnicki centar Rijeka /ID# 150714
state: Primorsko-goranska Zupanija
city: Split
country: Croatia
facility: Klinicki Bolnicki Centar (KBC) Split /ID# 213989
state: Splitsko-dalmatinska Zupanija
city: Grad Zagreb
country: Croatia
facility: Duplicate_Poliklinika Solmed /ID# 211567
city: Zadar
country: Croatia
facility: Zadar General Hospital /ID# 150261
city: Prague
country: Czechia
facility: Iscare Klinické Centrum /ID# 209279
state: Praha 9
city: Hradec Kralove
country: Czechia
facility: Hepato-Gastroenterologie HK, s.r.o. /ID# 150946
city: Olomouc
country: Czechia
facility: CTCenter MaVe s.r.o. /ID# 150903
city: Ostrava
country: Czechia
facility: ARTROSCAN s.r.o. /ID# 150502
city: Pardubice
country: Czechia
facility: Nemocnice Pardubickeho kraje, a.s. /ID# 213541
city: Praha
country: Czechia
facility: Nemocnice Milosrdnych sester sv. Karla Boromejskeho v Praze /ID# 216224
city: Praha
country: Czechia
facility: Axon Clinical, s.r.o. /ID# 152477
city: Mustamäe Linnaosa
country: Estonia
facility: North Estonia Medical Centre /ID# 160871
state: Harjumaa
city: Tallinn
country: Estonia
facility: West Tallinn Central Hospital /ID# 150490
state: Harjumaa
city: Tallinn
country: Estonia
facility: East Tallinn Central Hospital - Magdaleena Unit /ID# 150488
state: Harjumaa
city: Tartu
country: Estonia
facility: Tartu University Hospital /ID# 150489
city: Tampere
country: Finland
facility: Tampereen yliopistollinen sairaala /ID# 150376
state: Pirkanmaa
city: Turku
country: Finland
facility: Turku University Hospital /ID# 169895
state: Varsinais-Suomi
city: Helsinki
country: Finland
facility: Duplicate_Helsinki Univ Central Hospital /ID# 154283
city: Jyvaskyla
country: Finland
facility: Keski-Suomen Sairaala Nova /ID# 155665
city: Mikkeli
country: Finland
facility: Laakarikeskus Ikioma /ID# 150377
city: Nice
country: France
facility: Chu de Nice-Hopital L'Archet Ii /Id# 152608
state: Alpes-Maritimes
city: Montpellier Cedex 5
country: France
facility: CHU Montpellier - Hopital Saint Eloi /ID# 200088
state: Herault
city: Lille
country: France
facility: CHRU Lille - Hopital Claude Huriez /ID# 152609
state: Nord
city: Pierre Benite CEDEX
country: France
facility: HCL - Hopital Lyon Sud /ID# 152540
state: Rhone
city: La Roche Sur Yon
country: France
facility: CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 165749
state: Vendee
city: SAINT-ETIENNE Cedex 1
country: France
facility: CHU de Saint-Etienne, Hopital Nord /ID# 165756
city: Mannheim
country: Germany
facility: Universitatsklinikum Mannheim /ID# 150405
state: Baden-Wuerttemberg
city: Tübingen
country: Germany
facility: Universitaetsklinikum Tuebingen /ID# 151698
state: Baden-Wuerttemberg
city: Frankfurt am Main
country: Germany
facility: Duplicate_Agaplesion Markus Krankenhaus /ID# 161870
state: Hessen
city: Munster
country: Germany
facility: Duplicate_Universitaetsklinikum Muenster /ID# 150402
state: Niedersachsen
city: Herne
country: Germany
facility: Gastroenterologische Gemeinschaftspraxis Herne /ID# 214575
state: Nordrhein-Westfalen
city: Saarbrücken
country: Germany
facility: Zentrum für Gastroenterologie Saar MVZ GmbH /ID# 215812
state: Saarland
city: Kiel
country: Germany
facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 161871
state: Schleswig-Holstein
city: Berlin
country: Germany
facility: MVZ fuer Gastroenterlogie am Bayerischen Platz /ID# 151697
city: Muenster
country: Germany
facility: Medizinisches Versorgungszentrum Portal 10 /ID# 207136
city: Wiesbaden
country: Germany
facility: Praxis medicum /ID# 150404
city: Athens
country: Greece
facility: General Hospital of Athens Laiko /ID# 208672
state: Attiki
city: Athens
country: Greece
facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 202101
state: Attiki
city: Heraklion
country: Greece
facility: University General Hospital of Heraklion PA.G.N.I /ID# 150236
state: Kriti
city: Athens
country: Greece
facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 150406
city: Ioannina
country: Greece
facility: University General Hospital of Ioannina /ID# 164247
city: Thessaloniki
country: Greece
facility: Theageneio Anticancer Hospital /ID# 164187
city: Thessaloniki
country: Greece
facility: General Hospital of Thessaloniki Hippokrateio /ID# 209522
city: Kecskemet
country: Hungary
facility: Meditres Kft. /ID# 151597
state: Bacs-Kiskun
city: Szombathely
country: Hungary
facility: Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz /ID# 150410
state: Vas
city: Bekescsaba
country: Hungary
facility: Bekes Megyei Kozponti Korhaz /ID# 151601
city: Budapest
country: Hungary
facility: Semmelweis Egyetem /ID# 150409
city: Sopron
country: Hungary
facility: Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet /ID# 151599
city: Szekesfehervar
country: Hungary
facility: Mentahaz Maganorvosi Kozpont /ID# 206977
city: Dublin 8
country: Ireland
facility: St James Hospital /ID# 150413
state: Dublin
city: Elm Park
country: Ireland
facility: St Vincent's University Hospital /ID# 150411
state: Dublin
city: Cork
country: Ireland
facility: Mercy University Hospital /ID# 153794
city: Dublin
country: Ireland
facility: Beaumont Hospital /ID# 150414
city: Galway
country: Ireland
facility: University Hospital Galway /ID# 150412
city: Haifa
country: Israel
facility: Rambam Health Care Campus /ID# 150416
state: H_efa
city: Be'er Sheva
country: Israel
facility: Soroka University Medical Center /ID# 156562
state: HaDarom
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center /ID# 163139
state: Yerushalayim
city: Jerusalem
country: Israel
facility: Hadassah Medical Center-Hebrew University /ID# 165119
state: Yerushalayim
city: Bologna
country: Italy
facility: IRCCS AOU di Bologna - Policlinico Sant'Orsola-Malpighi /ID# 150424
state: Emilia-Romagna
city: Rozzano
country: Italy
facility: IRCCS Istituto Clinico Humanitas /ID# 151363
state: Lombardia
city: Milan
country: Italy
facility: ASST Fatebenefratelli Sacco - Ospedale Fatebenefratelli e Oftalmico /ID# 150605
state: Milano
city: Rho
country: Italy
facility: ASST Rhodense/Presidio Ospedaliero di Rho /ID# 216673
state: Milano
city: Rome
country: Italy
facility: Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 150425
state: Roma
city: Rome
country: Italy
facility: Duplicate_Azienda Ospedaliera San Camillo Forlanini /ID# 151362
state: Roma
city: Rome
country: Italy
facility: Presidio Columbus-Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Un /ID# 150420
state: Roma
city: Negrar
country: Italy
facility: IRCCS Ospedale Sacro Cuore Don Calabria /ID# 201726
state: Verona
city: Milano
country: Italy
facility: Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico /ID# 150421
city: Palermo
country: Italy
facility: Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello /ID# 150263
city: Nagakute
country: Japan
facility: Aichi Medical University Hospital /ID# 151994
state: Aichi
city: Nagoya shi
country: Japan
facility: Nagoya City University Hospital /ID# 151949
state: Aichi
city: Nagoya-shi
country: Japan
facility: Nagoya University Hospital /ID# 152728
state: Aichi
city: Toyohashi-shi
country: Japan
facility: Toyohashi Municipal Hospital /ID# 171470
state: Aichi
city: Toyota-shi
country: Japan
facility: Ieda Hospital /ID# 157782
state: Aichi
city: Hirosaki-shi
country: Japan
facility: National Hospital Organization Hirosaki General Medical Center /ID# 152761
state: Aomori
city: Abiko-shi
country: Japan
facility: Tokatsu Tsujinaka Hospital /ID# 214964
state: Chiba
city: Kashiwa-shi
country: Japan
facility: Tsujinaka Hospital Kashiwanoha /ID# 209572
state: Chiba
city: Sakura-shi
country: Japan
facility: Toho University Sakura Medical Center /ID# 151935
state: Chiba
city: Urayasu-shi
country: Japan
facility: Juntendo University Urayasu Hospital /ID# 208783
state: Chiba
city: Fukui-shi
country: Japan
facility: Fukui Prefectural Hospital /ID# 210450
state: Fukui
city: Chikushino-shi
country: Japan
facility: Fukuoka University Chikushi Hospital /ID# 152627
state: Fukuoka
city: Fukuoka-shi
country: Japan
facility: Saiseikai Fukuoka Genaral Hospital /ID# 209481
state: Fukuoka
city: Fukuoka-shi
country: Japan
facility: Kyushu University Hospital /ID# 152525
state: Fukuoka
city: Kitakyushu
country: Japan
facility: Duplicate_Kitakyushu Municipal Medical Center /ID# 152589
state: Fukuoka
city: Kurume-shi
country: Japan
facility: Kurume University Hospital /ID# 151977
state: Fukuoka
city: Ogaki-shi
country: Japan
facility: Ogaki Municipal Hospital /ID# 208226
state: Gifu
city: Fukuyama-shi
country: Japan
facility: NHO Fukuyama Medical Center /ID# 206294
state: Hiroshima
city: Hiroshima-shi
country: Japan
facility: Hiroshima University Hospital /ID# 151952
state: Hiroshima
city: Asahikawa-shi
country: Japan
facility: Asahikawa Medical University Hospital /ID# 170281
state: Hokkaido
city: Obihiro-shi
country: Japan
facility: Obihiro kosei Hospital /ID# 210425
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo Tokushukai Hospital /ID# 209449
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 151705
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo Medical University Hospital /ID# 206493
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo Higashi Tokushukai Hospital /ID# 208495
state: Hokkaido
city: Kobe-shi
country: Japan
facility: Aoyama Clinic /ID# 152048
state: Hyogo
city: Nishinomiya-shi
country: Japan
facility: Hyogo Medical University Hospital /ID# 152433
state: Hyogo
city: Higashi Ibaraki-gun
country: Japan
facility: Duplicate_National Hospital Organization Mito Medical Center /ID# 152626
state: Ibaraki
city: Kanazawa-shi
country: Japan
facility: Kanazawa University Hospital /ID# 207810
state: Ishikawa
city: Morioka
country: Japan
facility: Iwate Medical University Hospital - Morioka /ID# 203412
state: Iwate
city: Kagoshima-shi
country: Japan
facility: Imamura General Hospital /ID# 227138
state: Kagoshima
city: Kagoshima-shi
country: Japan
facility: Idzuro Imamura Hospital /ID# 207640
state: Kagoshima
city: Kagoshima-shi
country: Japan
facility: Sameshima Hospital /ID# 206673
state: Kagoshima
city: Kagoshima-shi
country: Japan
facility: Kagoshima IBD Gastroenterology Clinic /ID# 245222
state: Kagoshima
city: Kawasaki-shi
country: Japan
facility: St. Marianna University Hospital /ID# 209452
state: Kanagawa
city: Yokohama shi
country: Japan
facility: Yokohama City University Medical Center /ID# 169900
state: Kanagawa
city: Yokohama-shi
country: Japan
facility: Showa University Fujigaoka Hospital /ID# 208223
state: Kanagawa
city: Kyoto-shi
country: Japan
facility: Japanese Red Cross Kyoto Daiichi Hosital /ID# 152358
state: Kyoto
city: Kyoto-shi
country: Japan
facility: Kyoto University Hospital /ID# 211808
state: Kyoto
city: Tsu-shi
country: Japan
facility: Mie University Hospital /ID# 207253
state: Mie
city: Yokkaichi-shi
country: Japan
facility: Yokkaichi Hazu Medical Center /ID# 214349
state: Mie
city: Sendai-shi
country: Japan
facility: National Hospital Organization Sendai Medical Center /ID# 209529
state: Miyagi
city: Omura-shi
country: Japan
facility: NHO Nagasaki Medical Center /ID# 210821
state: Nagasaki
city: Yamatotakada-shi
country: Japan
facility: Kenseikai Dongo Hospital /ID# 208102
state: Nara
city: Niigata-shi
country: Japan
facility: Saiseikai Niigata Hospital /ID# 209923
state: Niigata
city: Niigata-shi
country: Japan
facility: Niigata University Medical & Dental Hospital /ID# 218050
state: Niigata
city: Oita-shi
country: Japan
facility: Ishida Clinic of IBD and Gastroenterology /ID# 210118
state: Oita
city: Kurashiki-shi
country: Japan
facility: Chikuba Hospital for Proctological and Gastrointestinal Diseases /ID# 157820
state: Okayama
city: Okayama-shi
country: Japan
facility: Duplicate_Okayama University Hospital /ID# 217924
state: Okayama
city: Osaka-shi
country: Japan
facility: Kinshukai Infusion Clinic /ID# 207866
state: Osaka
city: Osaka-shi
country: Japan
facility: Kitano Hospital, Tazuke Kofukai Medical Research Institute /ID# 210396
state: Osaka
city: Osaka-shi
country: Japan
facility: Osaka City General Hospital /ID# 152703
state: Osaka
city: Osaka-shi
country: Japan
facility: Japanese Red Cross Osaka Hospital /ID# 209477
state: Osaka
city: Osaka-shi
country: Japan
facility: Osaka Metropolitan University Hospital /ID# 152681
state: Osaka
city: Takatsuki-shi
country: Japan
facility: Shoyukai Fujita Gastroenterological Hospital /ID# 216494
state: Osaka
city: Toyonaka-shi
country: Japan
facility: Toyonaka Municipal Hospital /ID# 217083
state: Osaka
city: Saga-shi
country: Japan
facility: Saga University Hospital /ID# 209272
state: Saga
city: Kawagoe-shi
country: Japan
facility: Saitama Medical Center /ID# 152019
state: Saitama
city: Saitama-shi
country: Japan
facility: Tokitokai Tokito clinic /ID# 152676
state: Saitama
city: Higashi-ohmi-shi
country: Japan
facility: National Hospital Organization Higashi-Ohmi General Medical Center /ID# 210711
state: Shiga
city: Izumo-shi
country: Japan
facility: Shimane University Hospital /ID# 208906
state: Shimane
city: Hamamatsu-shi
country: Japan
facility: Hamamatsu University Hospital /ID# 205709
state: Shizuoka
city: Sunto-gun
country: Japan
facility: NHO Shizuoka Medical Center /ID# 163571
state: Shizuoka
city: Bunkyo-ku
country: Japan
facility: Institute of Science Tokyo Hospital /ID# 152017
state: Tokyo
city: Chuo-ku
country: Japan
facility: St.Luke's International Hospital /ID# 208075
state: Tokyo
city: Hachioji-shi
country: Japan
facility: Tokai University Hachioji Hospital /ID# 152584
state: Tokyo
city: Minato-ku
country: Japan
facility: Kitasato University Kitasato Institute Hospital /ID# 152687
state: Tokyo
city: Mitaka-shi
country: Japan
facility: Kyorin University Hospital /ID# 153195
state: Tokyo
city: Shinjuku-ku
country: Japan
facility: Duplicate_Center hospital of the National Center for Global Health and Medicine /ID# 209533
state: Tokyo
city: Shinjuku-ku
country: Japan
facility: Tokyo Women's Medical University Hospital /ID# 205978
state: Tokyo
city: Yamagata-shi
country: Japan
facility: Yamagata University Hospital /ID# 171468
state: Yamagata
city: Shunan-shi
country: Japan
facility: Tokuyama Central Hospital /ID# 216995
state: Yamaguchi
city: Kofu-shi
country: Japan
facility: Yamanashi Prefectural Central Hospital /ID# 151909
state: Yamanashi
city: Tokyo
country: Japan
facility: Teikyo University Hospital /ID# 209865
city: Busan
country: Korea, Republic of
facility: Dong-A University Medical Center /ID# 161568
state: Busan Gwang Yeogsi
city: Busan
country: Korea, Republic of
facility: Pusan National University Hospital /ID# 161569
state: Busan Gwang Yeogsi
city: Guri
country: Korea, Republic of
facility: Duplicate_Hanyang University Gurihospital /ID# 150431
state: Gyeonggido
city: Seongnam
country: Korea, Republic of
facility: Duplicate_CHA University Bundang Medical Center /ID# 161567
state: Gyeonggido
city: Suwon
country: Korea, Republic of
facility: The Catholic University Of Korea St. Vincent's Hospital /ID# 150434
state: Gyeonggido
city: Seoul
country: Korea, Republic of
facility: Kangbuk Samsung Hospital /ID# 150435
state: Seoul Teugbyeolsi
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center /ID# 159155
state: Seoul Teugbyeolsi
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center /ID# 150433
state: Seoul Teugbyeolsi
city: Daegu
country: Korea, Republic of
facility: Yeungnam University Medical Center /ID# 150432
city: Seoul
country: Korea, Republic of
facility: Yonsei University Health System Severance Hospital /ID# 161566
city: Riga
country: Latvia
facility: VCA Polyclinic Aura /ID# 150436
city: Riga
country: Latvia
facility: Pauls Stradins Clinical University Hospital /ID# 153183
city: Kaunas
country: Lithuania
facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 150439
city: Klaipeda
country: Lithuania
facility: Klaipeda university hospital /ID# 163501
city: Klaipeda
country: Lithuania
facility: Klaipeda University Hospital /ID# 163719
city: Vilnius
country: Lithuania
facility: Duplicate_Vilnius University Hospital /ID# 164172
city: Alor Setar
country: Malaysia
facility: Hospital Sultanah Bahiyah /ID# 152310
state: Kedah
city: Ampang
country: Malaysia
facility: Hospital Ampang /ID# 152311
state: Selangor
city: Kuala Lumpur
country: Malaysia
facility: Universiti Kebangsaan Malaysia (UKM) Medical Centre /ID# 152313
state: Selangor
city: Kuala Lumpur
country: Malaysia
facility: Uni Malaya MC /ID# 150440
city: Leon
country: Mexico
facility: Morales Vargas Centro de Investigacion S.C. /ID# 211327
state: Guanajuato
city: Guadalajara
country: Mexico
facility: Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 202334
state: Jalisco
city: Monterrey
country: Mexico
facility: Centro Regiomontano de Estudios Clínicos ROMA S.C /ID# 150265
state: Nuevo Leon
city: Nijmegen
country: Netherlands
facility: Radboud Universitair Medisch Centrum /ID# 151701
state: Gelderland
city: Amsterdam
country: Netherlands
facility: Amsterdam UMC, locatie AMC /ID# 150617
state: Noord-Holland
city: Leiden
country: Netherlands
facility: Leids Universitair Medisch Centrum /ID# 152625
state: Zuid-Holland
city: Rotterdam
country: Netherlands
facility: Duplicate_Erasmus Medisch Centrum /ID# 150619
state: Zuid-Holland
city: Utrecht
country: Netherlands
facility: Universitair Medisch Centrum Utrecht /ID# 152776
city: Lorenskog
country: Norway
facility: Akershus Universitetssykehus_MAIN /ID# 150622
state: Akershus
city: Tromsø
country: Norway
facility: Universitetssykehuset I Nord-Norge /ID# 152836
state: Troms
city: Torun
country: Poland
facility: Gastromed Sp. z o.o /ID# 216198
state: Kujawsko-pomorskie
city: Warszawa
country: Poland
facility: Centrum Zdrowia MDM /ID# 150626
state: Mazowieckie
city: Warszawa
country: Poland
facility: Panstwowy Instytut Medyczny MSWiA w Warszawie /ID# 150627
state: Mazowieckie
city: Warszawa
country: Poland
facility: Centrum Medyczne Reuma Park /ID# 150624
state: Mazowieckie
city: Warszawa
country: Poland
facility: Vivamed Sp. z o.o. /ID# 216743
state: Mazowieckie
city: Warszawa
country: Poland
facility: Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 215733
state: Mazowieckie
city: Sopot
country: Poland
facility: Endoskopia Sp. z o.o. /ID# 152940
state: Pomorskie
city: Guimaraes
country: Portugal
facility: Duplicate_Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 151616
state: Braga
city: Santa Maria Da Feira
country: Portugal
facility: Centro Hospitalar de Entre Douro e Vouga /ID# 152336
state: Porto
city: Almada
country: Portugal
facility: Duplicate_Hospital Garcia de Orta, EPE /ID# 151622
state: Setubal
city: Braga
country: Portugal
facility: 2CA-Braga, Hospital de Braga /ID# 151617
city: Lisboa
country: Portugal
facility: Duplicate_Centro Hospitalar Universitario Lisboa Central, EPE - Hospital dos Cap /ID# 151620
city: Lisboa
country: Portugal
facility: Unidade Local de Saude de Santa Maria, EPE /ID# 151615
city: Porto
country: Portugal
facility: Centro Hospitalar Universitario de Sao Joao, EPE /ID# 151619
city: Viana Do Castelo
country: Portugal
facility: Unidade Local de Saude do Alto Minho, EPE /ID# 151618
city: San Juan
country: Puerto Rico
facility: School of Medicine University of Puerto Rico-Medical Science Campus /ID# 150629
city: Kaliningrad
country: Russian Federation
facility: Immanuel Kant Baltic Federal University /ID# 202129
state: Kaliningradskaya Oblast
city: St. Petersburg
country: Russian Federation
facility: NW State Medical Univ na Mechn /ID# 169332
state: Leningradskaya Oblast
city: Petrozavodsk
country: Russian Federation
facility: Republican hospital named after V.A. Baranov /ID# 206508
state: Murmanskaya Oblast
city: Perm
country: Russian Federation
facility: Perm Clinical Center of the Federal Medical and Biological Agency /ID# 150634
state: Permskiy Kray
city: Samara
country: Russian Federation
facility: Medical Company Hepatolog /ID# 200208
state: Samarskaya Oblast
city: Pyatigorsk
country: Russian Federation
facility: LLC Novaya Klinika /ID# 208106
state: Stavropol Skiy Kray
city: Kazan
country: Russian Federation
facility: Kazan State Medical University /ID# 166040
state: Tatarstan, Respublika
city: Moscow
country: Russian Federation
facility: Olla-Med Clinic /ID# 215334
city: Pushkin
country: Russian Federation
facility: Euromedservice /ID# 208968
city: Stavropol
country: Russian Federation
facility: Duplicate_Stavropol State Medical Univ /ID# 150635
city: Belgrade
country: Serbia
facility: Clinical Hosp Center Zvezdara /ID# 150641
state: Beograd
city: Belgrade
country: Serbia
facility: Military Medical Academy /ID# 150643
state: Beograd
city: Belgrade
country: Serbia
facility: University Clinical Center Serbia /ID# 150642
state: Beograd
city: Belgrade
country: Serbia
facility: Clin Hosp Ctr Bezanijska Kosa /ID# 150640
state: Beograd
city: Leskovac
country: Serbia
facility: General Hospital Leskovac /ID# 217882
state: Jablanicki Okrug
city: NIS
country: Serbia
facility: Duplicate_University Clinical Center of Nis /ID# 151902
state: Nisavski Okrug
city: Kragujevac
country: Serbia
facility: University Clinical Center Kragujevac /ID# 150644
state: Pomoravski Okrug
city: Novi Sad
country: Serbia
facility: University Clinical Center Vojvodina /ID# 150759
city: Singapore
country: Singapore
facility: National University Hospital /ID# 150583
city: Singapore
country: Singapore
facility: Gleneagles Medical Centre /ID# 206020
city: Singapore
country: Singapore
facility: Tan Tock Seng Hospital /ID# 150646
city: Banska Bystrica
country: Slovakia
facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 150869
state: Banskobystricky Kraj
city: Kosice
country: Slovakia
facility: B+B MED, s.r.o. /ID# 150584
state: Kosicky Kraj
city: Nove Zamky
country: Slovakia
facility: Fakultna nemocnica s poliklinikou Nove Zamky /ID# 211371
state: Nitriansky Kraj
city: Prešov
country: Slovakia
facility: Gastro I., s.r.o. /ID# 150585
state: Presovsky Kraj
city: Bratislava
country: Slovakia
facility: Medak s.r.o. /ID# 150550
city: Ilava
country: Slovakia
facility: Slovak Research Center Team Me /ID# 150240
city: Boksburg North
country: South Africa
facility: MD Search /ID# 157524
state: Gauteng
city: Johannesburg
country: South Africa
facility: Clinresco Centers /ID# 163625
state: Gauteng
city: Johannesburg
country: South Africa
facility: Lenasia Clinical Trial Centre /ID# 214361
state: Gauteng
city: Johannesburg
country: South Africa
facility: Wits Clinical Research /ID# 150586
state: Gauteng
city: Johannesburg
country: South Africa
facility: Wits Clinical Research , Wits Health Consortium (PTY) Ltd /ID# 157730
state: Gauteng
city: CAPE TOWN Milnerton
country: South Africa
facility: Spoke Research Inc /ID# 162203
state: Western Cape
city: Cape Town
country: South Africa
facility: Kingsbury Hospital /ID# 150587
state: Western Cape
city: Cape Town
country: South Africa
facility: Private Practice Dr MN Rajabally /ID# 155145
state: Western Cape
city: A Coruña
country: Spain
facility: Complejo Hospitalario Universitario A Coruña /ID# 203912
state: A Coruna
city: Santiago de Compostela
country: Spain
facility: Duplicate_Hospital Clínico Universitario de Santiago-CHUS /ID# 171492
state: A Coruna
city: Santander
country: Spain
facility: Hospital Universitario Marques de Valdecilla /ID# 216621
state: Cantabria
city: Las Palmas de Gran Canaria
country: Spain
facility: Hospital Universitario Dr. Negrin /ID# 203965
state: Las Palmas
city: Barcelona
country: Spain
facility: Hospital Clinic de Barcelona /ID# 150598
city: Cordoba
country: Spain
facility: Duplicate_Hospital Universitario Reina Sofia /ID# 154031
city: Madrid
country: Spain
facility: Hospital Universitario Ramon y Cajal /ID# 171491
city: Madrid
country: Spain
facility: Hospital Universitario La Paz /ID# 214541
city: Salamanca
country: Spain
facility: Hospital Universitario de Salamanca /ID# 150590
city: Valencia
country: Spain
facility: Hospital Universitario y Politecnico La Fe /ID# 150591
city: Gothenburg
country: Sweden
facility: Duplicate_Sahlgrenska University Hospital /ID# 152326
state: Vastra Gotalands Lan
city: Basel Town
country: Switzerland
facility: Universitätsspital Basel /ID# 161732
state: Basel-Stadt
city: St. Gallen
country: Switzerland
facility: Kantonsspital St. Gallen /ID# 152601
state: Sankt Gallen
city: Zurich
country: Switzerland
facility: University Hospital Zurich /ID# 152603
state: Zuerich
city: Bern
country: Switzerland
facility: Inselspital, Universitaetsspital Bern /ID# 152602
city: Taipei City
country: Taiwan
facility: National Taiwan University Hospital /ID# 150604
state: Taipei
city: Kaohsiung
country: Taiwan
facility: Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 150606
city: Taichung
country: Taiwan
facility: Chung Shan Medical University Hospital /ID# 150603
city: Taichung
country: Taiwan
facility: China Medical University Hospital /ID# 150600
city: Tainan
country: Taiwan
facility: National Cheng Kung University Hospital /ID# 151751
city: Taipei
country: Taiwan
facility: Taipei Veterans General Hosp /ID# 151750
city: Yenimahalle
country: Turkey
facility: Gazi Universitesi Tip Fakultes /ID# 150493
state: Ankara
city: Melikgazi
country: Turkey
facility: Duplicate_Erciyes University Medical Fac /ID# 150495
state: Kayseri
city: Cerrahpasa
country: Turkey
facility: Istanbul University Cerrahpasa Faculty of Medicine /ID# 150491
city: Istanbul
country: Turkey
facility: Umraniye Training and Res Hosp /ID# 163136
city: Istanbul
country: Turkey
facility: Marmara University Medical Fac /ID# 214573
city: Mersin
country: Turkey
facility: Mersin University Medical /ID# 163135
city: Kharkiv
country: Ukraine
facility: CNCE of Kharkiv Regional Council Regional Clinical Hospital /ID# 206941
state: Kharkivska Oblast
city: Lviv
country: Ukraine
facility: Lviv Regional Clinical Hospital /ID# 150508
state: Lvivska Oblast
city: Odesa
country: Ukraine
facility: Municipal Non-Commercial Enterprise Odesa Regional Clinical Hospital of the Od /ID# 162502
state: Odeska Oblast
city: Vinnytsia
country: Ukraine
facility: MNE Vinnytsia Regional Clinical Hospital n.a. M.I.Pyrogov /ID# 216302
state: Vinnytska Oblast
city: Vinnytsya
country: Ukraine
facility: Medical Center of the â€œHealth /ID# 162501
state: Vinnytska Oblast
city: Dnipro
country: Ukraine
facility: Municipal Enterprise "I.I. Mechnikov Dnipropetrovsk Regional Clinical Hospital" /ID# 207731
city: Kropyvnytskyi
country: Ukraine
facility: PE PMC Acinus, Medical and Diagnostic Center /ID# 217219
city: Kyiv
country: Ukraine
facility: Kyiv City Clinical Hospital No.18 /ID# 150505
city: Kyiv
country: Ukraine
facility: Medical Center of LLC "Medical Center "Consilium Medical" /ID# 217448
city: Kyiv
country: Ukraine
facility: CNPE of Kyiv Regional Council Kyiv Regional Hospital /ID# 217374
city: Exeter
country: United Kingdom
facility: Royal Devon & Exeter Hospital /ID# 150510
state: Devon
city: Basingstoke
country: United Kingdom
facility: Hampshire Hospitals NHS Foundation Trust /ID# 150511
state: Essex
city: London
country: United Kingdom
facility: Barts Health NHS Trust /ID# 150515
state: Greater London
city: Glasgow
country: United Kingdom
facility: NHS Greater Glasgow and Clyde /ID# 163788
state: Scotland
city: Bath
country: United Kingdom
facility: Royal United Hospitals Bath /ID# 154211
city: Birmingham
country: United Kingdom
facility: University Hospitals Birmingham NHS Foundation Trust /ID# 150513
city: Huddersfield
country: United Kingdom
facility: Calderdale and Huddersfield NHS Foundation Trust /ID# 217659
city: Tooting
country: United Kingdom
facility: St George's University Hospitals NHS Foundation Trust /ID# 208376
Study officials:
affiliation: AbbVie
name: ABBVIE INC.
role: STUDY_DIRECTOR
References: