Clinical trial NCT04613050: Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID- 19 Patients
Official title: Effect of Respiratory Versus Aerobic Training on Respiratory and Immunity Efficiency in Recovered COVID- 19 Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Covid 19 Infection
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2020-11-03
Enrollment: 80
Sex: ALL
Minimum age (years): 35
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.

Detailed description: This study will be conducted on eighty patients of both sexes with age ranging from 35 to 45years. The will be recovered from COVID-19 infection with chest symptoms. They will be selected from Nasr city police authority hospital. They will be randomly assigned into 3 equal groups.

Participants will be assigned into 3 groups equal in number (group A, group B, group C)

Group A (Respiratory Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive respiratory training for 6 weeks.

Group B : (Aerobic Training Group) : It will include 30 patients of both sexes, recovered from COVID-19 infection. In addition to medical drugs, they will receive aerobic training for 6 weeks

Group C : (control group) :It will include 20 patients of both sexes, recovered from COVID-19 infection on medical drugs only will receive no exercise as control group.

Eligibility criteria: Inclusion Criteria:

* Patients recovered from COVID -19 infection.
* Patients with body mass index 25 - 35 kg/m2
* Patients previously diagnosed with chest symptoms of COVID- 19 infection.
* Patients' body temperature less than 37.5
* Blood oxygen saturation ≥95%

Exclusion Criteria:

* Smokers
* Patients with Myocardial infarction
* Patients with diabetes.
* Patients with autoimmune disease.
* Patients with positive COVID -19 infection.
* Patients with previous chest diseases
* a heart rate of \>100 bpm
* a blood pressure of \<90/60 mmHg or \>140/90 mmHg
* a blood oxygen saturation of ≤95%
* other diseases that are not suitable for exercise (osteoarthritis knee - stroke patients, etc)

Primary outcomes:
measure: Complete blood picture
timeFrame: change from baseline at 6 weeks
measure: Arterial blood gases
timeFrame: change from baseline at 6 weeks
measure: 6-minute walk Distance
timeFrame: change from baseline at 6 weeks
measure: Breath-hold test
timeFrame: change from baseline at 6 weeks
measure: Oxygen saturation
timeFrame: change from baseline at 6 weeks
measure: Borg Dyspnea Scale score
timeFrame: change from baseline at 6 weeks
Secondary outcomes:
measure: Maximum oxygen consumption
timeFrame: change from baseline at 6 weeks
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Police hospital-Nasr city
Study officials:
References: