Clinical trial NCT03343769: Study of the Relationship Between the Strength of Ankle Movement Muscles and Postural Parameters in Elderly Fallers: Towards New Strategies for Screening and Management
Official title: Study of the Relationship Between the Strength of Ankle Movement Muscles and Postural Parameters in Elderly Fallers: Towards New Strategies for Screening and Management
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Persons Who Have Experienced a Sudden Uncontrolled Fall in the Absence of Outside Factors in the 6 Months Preceding the Consultation
Lead sponsor: Centre Hospitalier Universitaire Dijon
Sponsor class: OTHER
First posted: 2017-11-17
Enrollment: 34
Sex: ALL
Minimum age (years): 60
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patients followed at the Pôle de rééducation et de réadaptation

Brief summary: The quality of life of elderly citizens is to a great extent related to the maintenance of independence. The risk of falling and the loss of autonomy are two frequent problems associated with ageing. Although the impact of falls on functional outcomes and morbi-mortality in the elderly is well-established, the pathophysiological mechanisms underlying these falls are poorly understood. To better assess the risk of falling, numerous studies have investigated the use of dynamic and static posturography. These studies sought to characterise populations of fallers and non-fallers using parameters from postural analysis. Nonetheless, a new concept may emerge: weakening of the ankle movement muscles may be implicated in the age-related deterioration of posture. Even though it has been shown that this decrease occurs earlier and is more severe in fallers, the direct relationship between the strength of ankle movement muscles and balance parameters in elderly fallers has not yet been established. The existence of such a relationship would make it possible on the one hand to facilitate screening for those with a risk of falling, and on the other hand to enrich our understanding of the pathophysiology of the risk of falling. The perspective would therefore be to propose programmes focused on the strengthening of these deficient muscles.


Eligibility criteria: Inclusion Criteria:

Control group:

* Subjects who have provided written informed consent
* Subjects with national health insurance cover
* Subjects aged between 60 and 90 years old
* Able to understand simple instructions and exercise instructions and to provide informed consent
* with no diseases that could compromise postural abilities and ankle muscle strength.
* Subjects who have not experience a sudden uncontrolled fall in the absence of outside factors in the 6 months preceding inclusion.

Patients group

* Subjects who have provided written informed consent
* Subjects with national health insurance cover
* Subjects aged between 60 and 90 years old
* Able to understand simple instructions and exercise instructions and to provide informed consent
* Subjects who have experienced at least one sudden uncontrolled fall in the absence of outside factors in the 6 months preceding inclusion.

Exclusion Criteria:

* Acute balance disorders (central vestibular syndrome, infection or toxic cause)
* Chronic vestibular disease with proven clinical repercussions
* Any severe neuro-orthopedic disease impairing balance as well as physiological impairments due to ageing Any chronic neurological disorder (stroke, Parkinson syndrome...)
* Any psychiatric disorder able to compromise participation
* Non-corrected vision disorder
* Cancer or any progressive disease
* Treatment with psychotropic agents able to impair vigilance and posture
* Patients under guardianship
* Patients with an ADL score \<3 (total of 6 points), reflecting a clinically obvious high risk of falling

Primary outcomes:
measure: The sum of the moments of strength developed by the plantar flexor and dorsiflexor muscles (i.e. combined moment) in both ankles
timeFrame: Through study completion, an average of 1 month
measure: Mean total displacement of the Centre of Pressure in millimetres during the different stabilometry recordings.
timeFrame: Through study completion, an average of 1 month
Secondary outcomes:
Other outcomes:
Locations:
city: Dijon
country: France
facility: CHU Dijon Bourgogne
Study officials:
References: