Clinical trial NCT02843308: Enhancing Treatment of Hoarding Disorder With Personalized In-Home Sorting and Decluttering Practice
Official title: Building Community-Academic Partnerships for the Evidence-Based Treatment of Hoarding Disorder
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Hoarding Disorder
Hoarding
Clutter
Keywords: hoarding disorder
hoarding
clutter
Lead sponsor: Stanford University
Sponsor class: OTHER
Collaborators: name: National Institute of Mental Health (NIMH)
First posted: 2016-07-25
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The proposed study aims to investigate the efficacy of adding in-home decluttering practice to Buried in Treasures Workshop (BIT) facilitated group treatment for hoarding disorder.

Detailed description: Patients participate in Buried in Treasures Workshop (BIT) that has been shown to improve symptoms of hoarding disorder. The investigators hypothesize that adding in-home decluttering practice to the BIT workshop will decrease hoarding symptoms and level of clutter over time.

Eligibility criteria: Inclusion Criteria for Individuals with Hoarding Disorder:

1. Age 18 to 70 years
2. Either gender and all ethno-racial groups
3. Physically healthy male or non-pregnant female.
4. Hoarding Disorder primary condition
5. Willing and able to understand and complete consent and study procedures
6. English speaking

Exclusion Criteria for Individuals with Hoarding Disorder:

1. Current or past history of bipolar, psychotic or eating disorders, substance dependence, or substance abuse in the last year.
2. Clinically at risk of suicide with Columbia Suicide Severity Rating Scale (C-SSRS) Suicidal Ideation Subscale of 4 or higher (i.e. suicidal intent without specific plan)
3. Major medical or neurological conditions that increase the risk of participation or that would prevent completing assigned behavioral practice tasks.
4. Unable or unwilling to allow study staff into home for home assessment
5. Currently at high risk for eviction
6. Animal hoarding or squalor

Inclusion Criteria for Healthy Controls:

1. Age 18 to 70 years
2. Either gender and all ethno-racial groups
3. Physically healthy male or non-pregnant female.
4. Willing and able to understand and complete consent and study procedures
5. English speaking

Exclusion Criteria for Healthy Controls:

1. any current or lifetime psychiatric diagnosis
2. current or past use of psychotropic medication
3. major medical or neurological problem (e.g., unstable hypertension, seizure disorder, head trauma)
4. Metal in body or any other contraindication for MRI

Primary outcomes:
measure: Saving Inventory-Revised (SI-R)
timeFrame: Change from baseline at 8 weeks and 16 weeks after treatment
Secondary outcomes:
measure: Clutter Image Rating Scale
timeFrame: Change from baseline at 8 weeks and 16 weeks after treatment
Other outcomes:
Locations:
city: Stanford
country: United States
facility: Stanford University
state: California
Study officials:
affiliation: Stanford University
name: Carolyn Rodriguez, M.D., Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: