Clinical trial NCT01398904: Attentional Bias in Body Dysmorphic Disorder
Official title: Attentional Bias in Body Dysmorphic Disorder
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Body Dysmorphic Disorders
Keywords: BDD
Lead sponsor: Massachusetts General Hospital
Sponsor class: OTHER
First posted: 2011-07-21
Enrollment: 51
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study will include 40 participants, consisting of 20 BDD participants and 20 matched healthy controls.

Brief summary: Body Dysmorphic Disorder (BDD) participants will demonstrate greater attentional biases as compared to healthy control (HC) participants. Greater attention bias will be associated with greater distress. Greater attention bias will be associated with greater symptom severity.


Eligibility criteria: Inclusion Criteria for BDD and healthy control participants:

* males and females 18 years of age or older
* sufficient fluency of English to understand study staff, procedures, and questionnaires
* ability to provide informed consent

Inclusion for BDD participants only;

* primary diagnosis of Diagnostic and Statistical Manual 4th Edition (DSM-IV-TR) BDD
* BDD Yale-Brown Obsessive Compulsive Disorder score (Y-BOCS) of \> 20
* primary facial/head concern

Exclusion Criteria:

* Major medical or neurological conditions
* schizophrenia, schizoaffective disorder, or any other current lifetime DSM-IV psychotic disorder that is not attributable to delusional BDD
* current suicidality
* current homicidality

Exclusion criteria for healthy controls:

* Any current Axis I psychiatric illness
* history of BDD

Primary outcomes:
measure: Attention Pattern
timeFrame: Day 2
Secondary outcomes:
measure: Subjective Units of Distress Scale (SUDS)
timeFrame: Day 2
measure: Facial Attractiveness
timeFrame: Day 2
Other outcomes:
Locations:
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
Study officials:
affiliation: Massachusetts General Hospital
name: Sabine Wilhelm, Ph. D.
role: PRINCIPAL_INVESTIGATOR
affiliation: Massachusetts General Hospital
name: Jennifer Greenberg, Psy. D.
role: STUDY_DIRECTOR
References:
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citation: Carey P, Seedat S, Warwick J, van Heerden B, Stein DJ. SPECT imaging of body dysmorphic disorder. J Neuropsychiatry Clin Neurosci. 2004 Summer;16(3):357-9. doi: 10.1176/jnp.16.3.357.
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