Clinical trial NCT05005702: Effects of Inspiratory Muscle Training on Functional Capacity in Patients With Heart Failure.
Official title: Effects of Inspiratory Muscle Training on Functional Capacity in Patients With Heart Failure
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Heart Failure
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-08-13
Enrollment: 16
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: Heart failure is a complex clinical syndrome manifesting as inability to supply adequate blood flow throughout the body due to any structural or functional cardiac abnormality. The most common complaints are exercise intolerance, balance, dyspnea, and fatigue in patients with heart failure. It is clearly stated that pulmonary muscle weakness is prevalent and contributes to exercise intolerance in patients with heart failure. Purpose of the study was to evaluate the efficacy of inspiratory muscle traning on pulmonary muscle strength, pulmonary function test, functional capacity and quality of life. The tools used were 6-minute walk test, spirometry, IMT threshold device for IMT strength, and Quality of life. Study was conducted in 20 patients in single group and pre and post values were evaluated. The significance this study bears was that it helped defining for us that to how much extent we can improve the physical and pulmonary functional capacity using inspiratory muscle training. Data were analysed using spss 22.0.mean and standard deviation were calculated. Appropirate the stasitical test were used after checking normailty of data. Parametric test were used for data analysis using SPSS 22


Eligibility criteria: Inclusion Criteria:

1. Adults 40-60 years old who are sedentary.
2. Left ventricular ejection fraction of less than 45% evaluated by echocardiogram
3. Functional class II and III (New York Heart Association)
4. FEV1 less than 80%, predicted and/or FEV1/ forced vital capacity (FVC) ratio of more than 70% predicted, and clinical stability.
5. Ex-smokers of more than 5 years.

Exclusion Criteria:

1. Myocardial infarction
2. Complex arrhythmias
3. Uncontrolled hypertension
4. Angina pectoris.
5. Cognitive disorders
6. Recent any trauma.
7. Chronic respiratory disease.
8. Unstable angina
9. Recent viral infections (6 months before the study

Primary outcomes:
measure: Six-minute walk test (6MWT) Distance
timeFrame: 6 week
measure: Pulmonary function test.
timeFrame: 6 week
measure: SF-36
timeFrame: 6 week
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Sheikh Zayed Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Fareeha Kausar, PP-DPT
role: PRINCIPAL_INVESTIGATOR
References:
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