Clinical trial NCT06586008: The Association Between Visual Echocardiographic Scoring System and Clinical Outcomes in Patient With Acute Decompensated Heart Failure
Official title: The Association Between Visual Echocardiographic Scoring System and Clinical Outcomes in Patient With Acute Decompensated Heart Failure
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Acute Decompensated Heart Failure
Keywords: visual echocardiographic system
acute decompensated heart failure
mortality
Lead sponsor: Universitas Diponegoro
Sponsor class: OTHER
First posted: 2024-09-19
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patient with acute decompensated heart failure who fulfill eligibility criteria

Brief summary: This study aims to evaluate the association between visual echocardiographic scoring system (visual mitral and tricuspid = VMT score) with clinical outcome among patients with acute decompensated heart failure. Researchers will collect information based on hospital registry as secondary data of in patient who had diagnosed as acute decompensated heart failure. The data consist of demographic data, clinical presentation, laboratory, and echocardiographic result were collected from hospital registry by reviewing medical record and echocardiographic machine database. Then, the data was analyzed by using IBM SPSS Statistics v26.


Eligibility criteria: Inclusion Criteria:

* Patient with history of heart failure with reduced ejection fraction (LVEF \<40%)
* Age between 18 - 70 years old

Exclusion Criteria:

* Patient with pulmonary hypertension
* Patient with acute de novo heart failure (e.g. due to acute coronary syndrome)
* Significant valvular heart disease (more than moderate regurgitation or more than mild stenosis)
* Prior valve replacement/repair
* Patient with congenital heart disease
* Patient with pericardial disease
* Patient with poor echocardiographic images

Primary outcomes:
measure: Mortality
timeFrame: During hospitalization, up to 1 weeks
Secondary outcomes:
measure: ICCU Length of Stay
timeFrame: During hospitalization, up to 1 weeks
measure: Urine output
timeFrame: During hospitalization, up to 1 weeks
Other outcomes:
Locations:
city: Semarang
country: Indonesia
facility: Dr. Kariadi Central General Hospital
state: Central Of Java
Study officials:
References:
citation: Murayama M, Iwano H, Nishino H, Tsujinaga S, Nakabachi M, Yokoyama S, Aiba M, Okada K, Kaga S, Sarashina M, Chiba Y, Ishizaka S, Motoi K, Nishida M, Shibuya H, Kamiya K, Nagai T, Anzai T. Simple Two-Dimensional Echocardiographic Scoring System for the Estimation of Left Ventricular Filling Pressure. J Am Soc Echocardiogr. 2021 Jul;34(7):723-734. doi: 10.1016/j.echo.2021.02.013. Epub 2021 Mar 3.
citation: Murayama M, Iwano H, Obokata M, Harada T, Omote K, Kagami K, Tsujinaga S, Chiba Y, Ishizaka S, Motoi K, Tamaki Y, Aoyagi H, Nakabachi M, Nishino H, Yokoyama S, Tanemura A, Okada K, Kaga S, Nishida M, Nagai T, Kurabayashi M, Anzai T. Visual echocardiographic scoring system of the left ventricular filling pressure and outcomes of heart failure with preserved ejection fraction. Eur Heart J Cardiovasc Imaging. 2022 Apr 18;23(5):616-626. doi: 10.1093/ehjci/jeab208.