Clinical trial NCT03432650: Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy
Official title: Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy: A Double-Blinded Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Hip Disease
Lead sponsor: Hospital for Special Surgery, New York
Sponsor class: OTHER
First posted: 2018-02-14
Enrollment: 96
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Hip arthroscopy is performed frequently and the postoperative course often involves moderate to severe pain. There remains no definitive perioperative pain regimen that has been proven to be effective and safe for this ambulatory procedure. Some institutions perform peripheral nerve blocks either preoperatively or postoperatively as a rescue block. All of these PNBs lead to quadriceps weakness which may impede earlier mobilization and physical therapy. While some case reports exist, there have not been any studies evaluating the QLB for hip arthroscopy patients. As previously mentioned, the technique is easy to perform, well-tolerated by patients, and avoids side effects such as hypotension, urinary retention, or the quadriceps weakness associated with lumbar plexus blockade.


Eligibility criteria: Inclusion Criteria:

* Patients scheduled for hip arthroscopy
* Ability to follow study protocol
* English Speaking

Exclusion Criteria:

* Hepatic or renal insufficiency
* Younger than 18 years old and older than 80
* Allergy or intolerance to one of the study medications
* Chronic gabapentin/pregabalin use (regular use for longer than 3 months)
* Chronic opioid use (daily opioids use for longer than 3 months)
* Patients contraindicated to undergo a spinal anesthetic
* Non English Speakers

Primary outcomes:
measure: Numerical Pain Rating System (NRS) Pain Scores
timeFrame: 30min after Post Anesthesia Care Unite (PACU) arrival
measure: Numerical Pain Rating System (NRS) Pain Scores
timeFrame: 1 hour after Post Anesthesia Care Unite (PACU) arrival
measure: Numerical Pain Rating System (NRS) Pain Scores
timeFrame: 2 hours after Post Anesthesia Care Unite (PACU) arrival
measure: Numerical Pain Rating System (NRS) Pain Scores
timeFrame: 3 hours after Post Anesthesia Care Unite (PACU) arrival
measure: Numerical Pain Rating System (NRS) Pain Scores
timeFrame: 24 hours after Post Anesthesia Care Unite (PACU) arrival
Secondary outcomes:
measure: Opioid Use
timeFrame: After Surgery to Post Operative Day 1
measure: Number of Patients With Presence of IAFE (Intraabdominal Fluid Extravasation) Following Surgery
timeFrame: Immediately post-op in OR
measure: Number of Patients With Nausea/Vomiting
timeFrame: Up to Post Op Day 1
measure: Antiemetic Use
timeFrame: Up to Post Op Day 1
measure: Number of Participants With Hospital Admission
timeFrame: Up to Post Op Day 1
measure: Patient Satisfaction With Post Op Pain Control
timeFrame: Up to Post Op Day 1
measure: Patient Score on Quality of Recovery-40 (QoR40) Inventory.
timeFrame: Up to Post Op Day 1
measure: Change in Quadriceps Motor Strength on Surgical Side
timeFrame: Up to Post Op Day 1
measure: Urinary Retention
timeFrame: Up to Post Op Day 1
measure: Incidence of Hypotension
timeFrame: Up to Post Op Day 1
Other outcomes:
Locations:
city: New York
country: United States
facility: Hospital of Special Surgery
state: New York
Study officials:
affiliation: Hospital for Special Surgery, New York
name: Stephen Haskins, MD
role: PRINCIPAL_INVESTIGATOR
References: