Clinical trial NCT06665802: Avoidant and Restrictive Food Intake Disorders (ARFID) in Adolescence: Early Oral Development, Psychopathological Profile and Sensory Integration
Official title: Avoidant and Restrictive Food Intake Disorders (ARFID) in Adolescence: Early Oral Development, Psychopathological Profile and Sensory Integration
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Avoidant and Restrictive Food Intake Disorders
Keywords: Avoidant and Restrictive Food Intake Disorders
ARFID
Eating disorder
Adolescent
Depression
Autism
Anxiety
Sensory sensitivity
Lead sponsor: Assistance Publique - Hôpitaux de Paris
Sponsor class: OTHER
First posted: 2024-10-30
Enrollment: 90
Sex: ALL
Minimum age (years): 12
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adolescents diagnosed with ARFID less than 2 years before

Brief summary: The purpose of this study is to assess if adolescents affected with Avoidant and Restrictive Food Intake Disorders (ARFID) had more frequent precocious pediatric feeding disorders before 4 years old compared to healthy adolescents.

Detailed description: This research focuses on retrospective analysis of early pediatric feeding disorders seen for ARFID in adolescence in two departments of the DMU MEFADO.

This assessment will be implemented during a hospital visit by a questionnaire completed by the patient's parents covering the first years of the child's life in medical, behavioural and dietary terms. This questionnaire was created for this study and, therefore, is not validated for general population. The parents will also complete the Montreal Children Feeding scale based on their memories.

The Montreal Children Feeding scale is a validated parental self-questionnaire, allowing the screening of feeding and eating disorders in children under 6 years old. Since the study specific questionnaire is not validated, 60 non-ARFID controls will be included in the study for questionnaires completion. The research also focuses on the psychopathological profile of these adolescents with ARFID regarding their degree of anxiety, their degree of depression, their possible autistic traits and their sensory sensitivity. These aspects will be studied by validated self- and hetero-questionnaires standardized for these fields. The emotional expression of the parents will be assessed during a brief qualitative interview type "Five-Minute Speech Sample".

Eligibility criteria: Inclusion Criteria:

For all patients:

* Adolescent aged 12 to 18 (minors = 17 years 11 months)
* No opposition from parents and adolescent

For ARFID patients:

* Consulting at MDA or Necker for an ARFID diagnosed using DSM V criteria
* Whose first consultation for this disorder was less than 2 years ago

For non-ARFID patients:

* Consulting or hospitalized in orthopaedic surgery at Necker Hospital or Robert Debré Hospital for an acute traumatic reason
* Not diagnosed with a chronic illness

Exclusion Criteria:

For all patients:

- Parents and adolescents who do not speak French well enough to understand the questions on the scales and questionnaires

For ARFID patients:

- Diagnosis of autism spectrum disorder already made at the time of the consultation

For non-ARFID patients:

- Presence of a chronic organic or psychological illness, to limit the risk of including non ARFID patients at high risk of eating disorders

Primary outcomes:
measure: Frequency of pediatric feeding disorders (PFD)
timeFrame: 1 day
Secondary outcomes:
measure: Severity of eating disorders on growth consequences in ARFID adolescents
timeFrame: 1 day
measure: Sensory profile in ARFID adolescents
timeFrame: 1 day
measure: Anxiety in ARFID adolescents
timeFrame: 1 day
measure: Depression in ARFID adolescents
timeFrame: 1 day
measure: Autistic traits in ARFID adolescents
timeFrame: 1 day
measure: Parental profile in ARFID adolescents
timeFrame: 1 day
Other outcomes:
Locations:
city: Paris
country: France
facility: Hôpital Cochin
city: Paris
country: France
facility: Hôpital Necker - Enfants malades
city: Paris
country: France
facility: Hôpital Robert Debré
Study officials:
References:
citation: Abadie V. [Diagnostic approach in oral disorder in young children]. Arch Pediatr. 2004 Jun;11(6):603-5. doi: 10.1016/j.arcped.2004.03.040. No abstract available. French.
citation: Rein Z, Perdereau F, Curt F, Jeammet P, Fermanian J, Godart N. Expressed emotion and anorexia nervosa: the validation of the Five-Minute Speech Sample in reference to the Camberwell Family Interview. Int J Eat Disord. 2006 Apr;39(3):217-23. doi: 10.1002/eat.20245.
citation: Goday PS, Huh SY, Silverman A, Lukens CT, Dodrill P, Cohen SS, Delaney AL, Feuling MB, Noel RJ, Gisel E, Kenzer A, Kessler DB, Kraus de Camargo O, Browne J, Phalen JA. Pediatric Feeding Disorder: Consensus Definition and Conceptual Framework. J Pediatr Gastroenterol Nutr. 2019 Jan;68(1):124-129. doi: 10.1097/MPG.0000000000002188.
citation: Fisher MM, Rosen DS, Ornstein RM, Mammel KA, Katzman DK, Rome ES, Callahan ST, Malizio J, Kearney S, Walsh BT. Characteristics of avoidant/restrictive food intake disorder in children and adolescents: a "new disorder" in DSM-5. J Adolesc Health. 2014 Jul;55(1):49-52. doi: 10.1016/j.jadohealth.2013.11.013. Epub 2014 Feb 5.
citation: Diagnosis and Statistical Manual of Mental Disorders: DSM-5. 5th ed. Washington, DC, USA: American Psychiatric Association (2013).
citation: Monteleone P, Di Genio M, Monteleone AM, Di Filippo C, Maj M. Investigation of factors associated to crossover from anorexia nervosa restricting type (ANR) and anorexia nervosa binge-purging type (ANBP) to bulimia nervosa and comparison of bulimia nervosa patients with or without previous ANR or ANBP. Compr Psychiatry. 2011 Jan-Feb;52(1):56-62. doi: 10.1016/j.comppsych.2010.05.002. Epub 2010 Jul 1.
citation: Galmiche M, Dechelotte P, Lambert G, Tavolacci MP. Prevalence of eating disorders over the 2000-2018 period: a systematic literature review. Am J Clin Nutr. 2019 May 1;109(5):1402-1413. doi: 10.1093/ajcn/nqy342.