Clinical trial NCT05379738: Impact of Adapted Physical Activity on Patient's Recovery Following Allogeneic Stem Cell Transplantation for Hematological Malignancy
Official title: APALLO : Post Allogeneic Stem Cell Transplantation Adapted Physical Activity for Patient With Hematological Malignancies
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Haematological Malignancy
Lead sponsor: Centre Hospitalier Universitaire de Nice
Sponsor class: OTHER
First posted: 2022-05-18
Enrollment: 75
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: BASIC_SCIENCE

Brief summary: It is a study about adaptated physical activity for patients receiving a stem cell transplantation. They will benefit of 6 adaptated individuals lessons at home between 1 month and 3 months after stem cell transplantation. The study's goal is to observe if adaptated activity has an positive impact on weight loss and on life quality.


Eligibility criteria: Inclusion criteria :

* Patient aged 18 or more
* Patient with social security
* Patient who accept the study and sign the consent form
* Patient programmed for an allogenic stem cell transplantation

Non inclusion criteria :

* Patients with a guardianship
* Patients with a significant additional physic or mental disease

Exclusion criteria

* Patients who did not receive an allogeniac stem cell transplantation
* Patients still hospitalized between day 30 and day 100 after stem cell transplantation
* Patients who finally refuses the study
* Patients who develop a physical or mental incapacity to practice physical activity

Primary outcomes:
measure: weight loss
timeFrame: before stem cell transplantation, 1 month , 3 months, 1 year after stem cell transplantation
measure: weight loss
timeFrame: before stem cell transplantation, 1 month , 3 months, 1 year after stem cell transplantation
Secondary outcomes:
measure: patient's ability to attend the classes
timeFrame: 3 months after stem cell transplantation
measure: body mass index
timeFrame: before stem cell transplantation, 1 month , 3 months, 1 year after stem cell transplantation
measure: brachial muscle circumference
timeFrame: before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation
measure: grip strength evaluation
timeFrame: before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation
measure: short physical battery test
timeFrame: before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation
measure: Quality of Life Questionary C30 (QLQ-C30)
timeFrame: before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation
measure: in house developped physical activities questionary
timeFrame: before stem cell transplantation , 1 month , 3 months, 1 year after stem cell transplantation
Other outcomes:
Locations:
city: Nice
country: France
facility: CHU NICE, hopital ARCHET 1, hématologie
Study officials:
affiliation: CHU NICE, hopital ARCHET 1, hématologie
name: SOLDATI Alizée
role: PRINCIPAL_INVESTIGATOR
References: