Clinical trial NCT04942743: Clinical & MRI Finding of TMJ Disk Perforation
Official title: Clinical & MRI Finding of TMJ Disk Perforation
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: TMJ Disc Disorder
Lead sponsor: Al-Azhar University
Sponsor class: OTHER
First posted: 2021-06-28
Enrollment: 900
Sex: ALL
Minimum age (years): 19
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The sample originally included patients who provided consent to participate in this study and who ultimately underwent treatment for TMJD between 2008 and 2019.

Brief summary: the study aimed to evaluate the clinical and MRI finding of TMJ with disk perforation with predication of the risk factors.

Detailed description: The retrospective study included patients seeking treatment for TMD at Al-Azhar University Hospital and the outpatient clinic at the Faculty of Dental Medicine of Al-Azahr University. The sample originally included patients who provided consent to participate in this study and who ultimately underwent treatment for TMJD between 2008 and 2019.

Exclusion Inclusion criteria: Patients were included if they were older than 18 years and diagnosed with TMJD. criteria for this study included systemic diseases (the presence of polyarthritis or other rheumatic diseases), contraindications for MRI (e.g., implanted metal or medical devices, claustrophobia), the presence of neurologic disorders, head and neck cancer, oral submucous ﬁbrosis, a history of TMJ surgery, a history of previous nonsurgical treatment such as occlusal splints, and a history of joint injection with HA/PRP. Trauma patients with subcondylar fracture and patients with congenital and developmental disorders of the TMJ were also excluded from the study.

the study included 2 groups group 1: normal TMJ patients group 2: patients with TMJ internal derangement

Eligibility criteria: Inclusion Criteria:

* patients seeking treatment for TMD at Al-Azhar University Hospital and the outpatient clinic at the Faculty of Dental Medicine of Al-Azahr University.

Exclusion Criteria:

* Patients were included if they were older than 18 years and diagnosed with TMJD. criteria for this study included systemic diseases (the presence of polyarthritis or other rheumatic diseases), contraindications for MRI (e.g., implanted metal or medical devices, claustrophobia), the presence of neurologic disorders, head and neck cancer, oral submucous ﬁbrosis, a history of TMJ surgery, a history of previous nonsurgical treatment such as occlusal splints, and a history of joint injection with HA/PRP. Trauma patients with subcondylar fracture and patients with congenital and developmental disorders of the TMJ were also excluded from the study.

Primary outcomes:
measure: joint pain (VAS),
timeFrame: pre treatment
measure: (MVMO)
timeFrame: pretreatment
Secondary outcomes:
measure: joint sound
timeFrame: pretreatment
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Faculty of Dental Medicine Alazhar University
state: Nasr City
Study officials:
affiliation: Al-Azhar University
name: Ayman Hegab, Phd
role: PRINCIPAL_INVESTIGATOR
References: