Clinical trial NCT00587912: AIDS and Cancer Specimen Bank (ACSB)
Official title: AIDS and Cancer Specimen Bank (ACSB)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Kaposi's Sarcoma AIDS Related
Kaposi's Sarcoma Classical
Non-Hodgkin's Lymphoma
HEMATOPOIETIC SYSTEM
Cancer
AIDS
Keywords: Kaposi's Sarcoma AIDS Related
Kaposi's Sarcoma Classical
Non-Hodgkin's Lymphoma
HEMATOPOIETIC SYSTEM
Cancer
AIDS
Lead sponsor: Memorial Sloan Kettering Cancer Center
Sponsor class: OTHER
Collaborators: name: National Cancer Institute (NCI)
name: George Washington University
name: University of Hawaii
name: University of California, San Francisco
name: Kaiser Permanente
First posted: 2008-01-08
Enrollment: 65
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The Source of specimens will include patients screened for participation on protocols conducted by the AIDS Malignancy Consortium, as well as other patients with HIV infection and cancer who are not eligible for participation in AMC trials, and patients without HIV who have malignancies associated with HIV or with immunosuppression.

Brief summary: The purpose of this study is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non-AIDS associated malignancies.

The National Cancer Institute has set up a Bank for tissues and biological fluids from HIVpositive and HIV-negative individuals in order to have specimens available for scientists studying malignancies associated with HIV disease.

Detailed description: The overall goal of the AIDS and Cancer Specimen Bank is to obtain clinical specimens from pathologists and physicians involved in the diagnosis and care of patients with AIDS and non- AIDS associated malignancies. These specimens will be banked and linked to a clinical data set so that experimental results obtained by analysis of specific specimens can be linked to relevant clinical data. Contents of the ACSB will be made available to researchers through an application to the National Cancer Institute. Strict patient confidentiality protection guidelines are in place for all specimens in the ACSB. The objective of this protocol is to obtain clinical specimens from potential participants in clinical trials conducted by the AIDS Malignancies Consortium, and from other patients with and without HIV infection, who have AIDS-Associated malignancies.

Eligibility criteria: Inclusion Criteria:

* Patient \> 18 years of age
* Suspected or confirmed AIDS-Associated malignancy with or without HIV infection
* Will obtain fresh tissue and/or biological fluids
* Patient signed the correct version of the informed consent

Exclusion Criteria:

* N/A

Primary outcomes:
measure: Identify and improve access to tumor tissue, biological specimens, and associated clinical outcome data that could be utilized for research by the research community at-large on the pathogenesis of HIV and non-HIV associated malignancies.
timeFrame: 3 years
Secondary outcomes:
Other outcomes:
Locations:
city: New York
country: United States
facility: Memorial Sloan-Kettering Cancer Center
state: New York
Study officials:
affiliation: Memorial Sloan Kettering Cancer Center
name: David Straus, MD
role: PRINCIPAL_INVESTIGATOR
References: