Clinical trial NCT03476902: Feasibility, Acceptability, and Preliminary Efficacy of a Mobile App (nOCD) for OCD
Official title: Feasibility, Acceptability, and Preliminary Efficacy of a Mobile App (nOCD) for OCD
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Obsessive Compulsive Disorder (OCD)
Keywords: OCD
Mobile
Technology
CBT
Cognitive-Behavioral Therapy
Lead sponsor: New York State Psychiatric Institute
Sponsor class: OTHER
First posted: 2018-03-26
Enrollment: 33
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to evaluate the feasibility, acceptability, and potential usefulness of using a mobile application (nOCD) for treatment of obsessive compulsive disorder (OCD) in a sample of 25 adults (ages 18-65) in an 8 week trial. nOCD is a free iOS/Android application that provides treatment strategies. The study team will evaluate the effect of the application using gold-standard clinician-administered and self-report measures. Prior to downloading the application, participants will receive 4 (up to 5) in-person visit (orientation to the app and psychoeducation) and receive brief weekly phone check-ins. The long-term goal of this study is to use this information to develop new treatments for patients with OCD. All study procedures will be conducted on site at the New York State Psychiatric Institute.

Detailed description: The purpose of this study is to evaluate the feasibility, acceptability, and potential usefulness of using a mobile app (nOCD) for treatment of OCD in a sample of 25 adults (ages 18-65). nOCD is a free iOS/Android app that provides EX/RP-consistent treatment strategies. The study team will evaluate the effect of the app using gold-standard clinician-administered and self-report measures. Prior to downloading the app, participants will receive 4 (up to 5) in-person visits and receive brief weekly phone check-in. The long term goal of this line of research is to increase access to evidence-based treatment and to ultimately reach more patients giving them access to tools to reduce their OCD symptoms and improve their quality of life.

Eligibility criteria: Inclusion Criteria:

* Primary DSM-5 diagnosis of obsessive-compulsive disorder
* Age 18-65
* Not currently receiving psychotherapy focused on OCD symptoms, and no EX/RP within the past 12 weeks
* For those currently on medication: On a stable dose of psychiatric medication (for at least 12 weeks)
* Capacity to provide informed consent

Exclusion Criteria:

* Comorbid psychiatric conditions that significantly elevate the risk of study participation (e.g. psychotic disorders, bipolar disorder, evidence of dementia or other cognitive disorder, suicidality).

Primary outcomes:
measure: Feasibility and acceptability of using a therapist assisted mobile app using the System Usability Scale (SUS).
timeFrame: 8 weeks
measure: Effect of therapist assisted mobile app on OCD symptoms as assessed by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS).
timeFrame: Baseline and approximately 8 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: New York
country: United States
facility: New York State Psychiatric Institute
state: New York
Study officials:
affiliation: New York State Psychiatric Institute
name: Marina Gershkovich, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Gershkovich M, Middleton R, Hezel DM, Grimaldi S, Renna M, Basaraba C, Patel S, Simpson HB. Integrating Exposure and Response Prevention With a Mobile App to Treat Obsessive-Compulsive Disorder: Feasibility, Acceptability, and Preliminary Effects. Behav Ther. 2021 Mar;52(2):394-405. doi: 10.1016/j.beth.2020.05.001. Epub 2020 May 11.