Clinical trial NCT05604950: Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years
Official title: Sichuan Cancer Hospital & Institute
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Esophageal Squamous Cell Carcinoma
Esophagectomy
Radiotherapy
Chemotherapy
Lead sponsor: Sichuan Cancer Hospital and Research Institute
Sponsor class: OTHER
First posted: 2022-11-03
Enrollment: 2
Sex: ALL
Minimum age (years): 70
Maximum age (years): 100
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Data were obtained from the Sichuan Cancer Hospital \& Institute Esophageal Cancer Case Management and the department of radiation oncology multicenter databases. We retrospectively analyzed esophageal squamous cell carcinoma patients who were 70 years or older, who underwent esophagectomy or radiotherapy/chemotherapy from January 2009 to December 2017. Patients were divided into two groups: surgery and non-surgery groups. We then prospectively collected data on 284 patients with esophageal squamous cell carcinoma in the Sichuan Cancer Hospital for results verification.

Brief summary: To determine whether older patients who underwent esophagectomy had better outcome survival than those who were non-surgically treated.


Eligibility criteria: Inclusion Criteria:

1. Pathology confirmed ESCC,
2. Patients with esophagectomy or radiotherapy (RT)/chemotherapy (CT),
3. Age ≥ 70.

Exclusion Criteria:

1. Having other malignant tumours,
2. Missing of required data.

Primary outcomes:
measure: Selection of treatment modalities for elderly patients with oesophageal cancer
timeFrame: 2009.01.01-2017.12.30
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
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