Clinical trial NCT05985564: Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration
Official title: Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Congenital Diaphragmatic Hernia
Lead sponsor: Children's Hospital of Chongqing Medical University
Sponsor class: OTHER
First posted: 2023-08-14
Enrollment: 300
Sex: ALL
Maximum age (years): 14
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The Bochdalek hernia and the congenital diaphragmatic eventration were included in the study. They had undergone surgical treatment.The imaging results and the surgical results were analysis

Brief summary: The imaging manifestations of diaphragmatic hernia and diaphragmatic distension were retrospectively analyzed and summarized, combined with the surgical findings, to summarize the differences in indirect signs of diaphragmatic hernia and diaphragmatic distension, so as to achieve the purpose of differential diagnosis.Research contents: (1) To summarize the characteristics of indirect imaging signs in patients with diaphragmatic hernia, to sum up the incidence of each sign, to find new signs and the prognosis of each sign; (2) Summarize the characteristics of indirect imaging signs in patients with diaphragmatic distension, summarize the incidence of each sign, and search for new signs and the prognosis of each sign; (3) To summarize the differences in indirect signs of diaphragmatic hernia and diaphragmatic distension, as well as the differences in their incidence, and combined with their surgical findings, to summarize their image identification points


Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of diaphragmatic hernia with surgical treatment
* Clinical diagnosis of congenital diaphragmatic eventration with surgical treatment

Exclusion Criteria:

* Diaphragmatic hernia or congenital diaphragmatic eventration without surgical treatment
* Diaphragmatic hernia or congenital diaphragmatic eventration without imaging examination

Primary outcomes:
measure: The position of the stomach
timeFrame: 1 day during the test
measure: The position of the small intestine
timeFrame: 1 day during the test
Secondary outcomes:
measure: The morphology of the small intestine
timeFrame: 1 day during the test
measure: The position of the colon
timeFrame: 1 day during the test
measure: The morphology of the colon
timeFrame: 1 day during the test
Other outcomes:
Locations:
city: Chongqing
country: China
facility: Children's Hospital of Chongqing Medical University
Study officials:
References:
citation: Alamo L, Gudinchet F, Meuli R. Imaging findings in fetal diaphragmatic abnormalities. Pediatr Radiol. 2015 Dec;45(13):1887-900. doi: 10.1007/s00247-015-3418-5. Epub 2015 Aug 9.
citation: Brown BP, Clark MT, Wise RL, Timsina LR, Reher TA, Vandewalle RJ, Brown JJ, Saenz ZM, Gray BW. A multifactorial severity score for left congenital diaphragmatic hernia in a high-risk population using fetal magnetic resonance imaging. Pediatr Radiol. 2019 Dec;49(13):1718-1725. doi: 10.1007/s00247-019-04478-2. Epub 2019 Aug 14.
citation: Goodfellow T, Hyde I, Burge DM, Freeman NV. Congenital diaphragmatic hernia: the prognostic significance of the site of the stomach. Br J Radiol. 1987 Oct;60(718):993-5. doi: 10.1259/0007-1285-60-718-993.