Clinical trial NCT06981546: Modeling Clinical Outcomes in Gambling Addiction
Official title: Modeling Clinical Outcomes in Gambling Addiction
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Gambling Disorder
Keywords: Gambling disorders
Modeling outcomes
Socio-demographic Characteristics
Clinical psychiatric profiles
Lead sponsor: Hospices Civils de Lyon
Sponsor class: OTHER
First posted: 2025-05-20
Enrollment: 268
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 268 patients with gambling disorder according to DSM-5 criteria newly managed in one of the participating centers or who had an interruption in management of more than 6 months.

Brief summary: Gambling disorder (GD) is recognized as an addictive disorder. Financial consequences of GD are often dramatic, inducing professional, familial, legal and medical repercussions and particularly mental health consequences.

MOGADOR is a longitudinal, multicentric, prospective, prognostic study, which aims to identify factors predicting the evolution of french patients with GD in care centers particularly involved in the management of GD. The main goal will focus on evolution of DSM-5 (Diagnostic and Statistical Manual of Mental Disorder 5th edition) GD criteria during the first year of follow-up. The prognostic factors will be collected at base-line and they will be considered to influence the long-term prognosis of patients.

For patients suffering of GD, our main hypothesis is that initial factors like individual socio-demographic characteristics, clinical psychiatric profiles, addiction comorbidities, and behaviour are associated with the clinical prognosis (total remission of DSM-5 criteria of GD at 12 months).

MOGADOR will be the first study, aiming to model prognostic aspects of GB in populations specially monitored for this disorder.


Eligibility criteria: Inclusion Criteria:

* Patient, male or female, over 18 years old, consulting in one of the participating centers.
* DSM-5 criteria for gambling disorder at inclusion: at least 4 criteria present in the 12 months preceding the study.
* First treatment for gambling disorder or no treatment in the last 6 months (initiation or re-initiation of care).

Exclusion Criteria:

* Unable to be reached by phone.
* Unable to use the internet.
* Patient under antiparkinsonian treatment of the dopaminergic family.
* Being treated with a drug that may trigger/increase symptoms of gambling disorder (e.g. dopamine agonist).
* Subject under guardianship.

Primary outcomes:
measure: Partial remission of gambling disorder at 12 months (strictly less than 4 DSM-5 criteria)
timeFrame: DSM-5 criteria assessment will be conducted at 9 and 12 months after inclusion.
measure: modeling prognostic factors
timeFrame: at inclusion visit.
Secondary outcomes:
Other outcomes:
Locations:
city: Besancon
country: France
facility: Hôpital Jen Minjoz, CHU de Besançon
city: Bron
country: France
facility: Service Universitaire d'Addictologie de Lyon (SUAL), CH Le Vinatier
city: Bron
country: France
facility: Service Universitaire d'Addictologie de Lyon (SUAL), Groupement Hospitalier Est
city: Clermont-ferrand
country: France
facility: Service Universitaire d'Addictologie, CHU de Clermont-Ferrand
city: Lille
country: France
facility: Name of location * Service d'Addictologie, Groupe Hospitalier Seclin Carvin
city: Limoges
country: France
facility: Centre Expert Régional du Jeu Pathologique (CERJeP Limousin)
city: Nimes
country: France
facility: Service Universitaire d'Addictologie, CHU de Nîmes
city: Paris
country: France
facility: Assistance Publique des Hôpitaux de Paris, Hôpital Marmottan
city: St-etienne
country: France
facility: Hôpital de Bellevue, CHU de St-Etienne
Study officials:
References: