Clinical trial NCT05649423: Postural Drainage With and Without Percussion in Chronic Obstructive Pulmonary Disease
Official title: Effects of Postural Drainage With and Without Percussion on Mucus Clearance, Dyspnea and Quality of Life in Chronic Obstructive Pulmonary Disease
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Chronic Obstructive Pulmonary Disease
Keywords: COPD, Mucus, Dyspnea, cough, postural drainage, percussion
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-12-14
Enrollment: 34
Sex: ALL
Minimum age (years): 35
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Effects Of postural drainage with and without percussion on mucus clearance, dyspnea and quality of life in Chronic Obstructive Pulmonary disease. 34 Patients will be explained in detail about the procedure under study. Informed consent will be taken.

Subjects will be evaluated using the Modified medical research council and Dyspnea-12 Questionnaire for (dyspneal), St George's Respiratory Questionnaire for quality of life. Cough and Sputum assesment questionnaire for mucus clearance would be used. One group will be tested by Postural drainage techniques and the second group will be tested by Postural drainage with Percussion.

Detailed description: Chronic respiratory diseases refer to chronic diseases of the airways and other structures like alveoli bronchi and bronchioles of the lung. Some of the most common diseases include asthma, chronic obstructive pulmonary disease (COPD), and other respiratory allergies. COPD leads to permanent damaged airways, which causes them to become narrower making it difficult for air to go into and out of lungs it belongs to a group of progressive lung diseases that make it difficult to breathe - including chronic bronchitis and emphysema (assessed by pulmonary function and x-ray evidence).

People have difficulty breathing due to long-term damage to their lungs, caused mainly due to cigarette smoking, exposure to air pollution, exposure to fumes or particles at work, for example, welding fumes or coal dust and Alpha-1-antitrypsin deficiency, a genetic condition. Symptoms that badly effects the health of the patient includes cough, decreased exercise tolerance production, shortness of breath, and shortness of breath.

In this research, the effects of postural drainage with and without percussion on mucus clearance, dyspnea and quality of life would be determined. Chest physiotherapy is the term for a group of treatments designed to eliminate secretions, thus helping to decrease work of breathing, promote the expansion of the lungs, and prevent the lungs from collapse.

There is a large impact on quality of life for individuals living with COPD, decreased exercise tolerance, decreased ability to carry out activities of daily living (ADLs), anxiety, feelings of isolation, decreased social participation etc.

This study will be a randomized controlled trial. The study will be conducted in Sheikh Zaid hospital Lahore. In the present study under considerations we mainly look on the subjects meeting predetermined inclusion and exclusion criteria will be divided into two groups using lottery method. Sample size will be 34 which would include both male and female. Subjects irrespective of gender aged between 35-65 years of age are involved.

Eligibility criteria: Inclusion Criteria:

* • Age 35-65 years

  * Patients who have had exacerbations in the past month
  * Agreeing to participate in the study after having provided a written consent.
  * Patients with heavy Mucus secretions in Lungs Field
  * Diagnosed Patients of Chronic Obstructive Pulmonary Disease Stage 2(COPD)

Exclusion Criteria:

* • Patients on bronchodilators and steroids

  * Patients with severe Pulmonary Edema
  * Patients with severe rib fractures
  * History of any recent thoraco abdominal surgery(35)
  * Left ventricular Ejection Fraction (EF)
  * Anemic patients
  * Pregnant women

Primary outcomes:
measure: For Airway Clearance
timeFrame: 8weeks
measure: St. George's Respiratory Questionnaire (SGRQ) quality of life assessment
timeFrame: 8 weeks
measure: Spirometry For Airway clearance
timeFrame: 8 weeks
Secondary outcomes:
Other outcomes:
measure: Dyspnea-12
timeFrame: 8 weeks
Locations:
city: Lahore
country: Pakistan
facility: Sheikh Zaid Hospital
state: Punjab
Study officials:
affiliation: Riphah International University
name: Sumera Abdulhameed, MS
role: PRINCIPAL_INVESTIGATOR
References: