Clinical trial NCT05764421: Motor-cognitive Interventions Are Effective in Improving Cognitive Function in Older Adults With Mild Cognitive impairment--a Chinese Sample
Official title: Motor-cognitive Interventions Are Effective in Improving Cognitive Function in Older Adults With Mild Cognitive impairment--a Chinese Sample
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: MCI
Keywords: motor-cognitive intervention
older adults
cognitive ability
mild cognitive impairment
Lead sponsor: Qingdao University
Sponsor class: OTHER
First posted: 2023-03-10
Enrollment: 103
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Mild cognitive impairment (MCI) is a syndrome that occurs in the preclinical stage of Alzheimer, and early intervention can be effective in preventing Alzheimer, but further research is needed on intervention methods. In order to identify interventions that are more suitable for Chinese characteristics and to investigate the effects of a motor-cognitive intervention on the cognitive function of older adults with MCI, investigators screened 103 community-dwelling older adults with MCI aged 65 years and older in Qingdao, Shandong, China, and divided them into an intervention group and a control group, and administered a motor-cognitive intervention to the intervention group for 12 weeks. Investigators assessed the cognitive abilities of MCI participants using the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). There were no demographic differences between the intervention and control groups. Investigators found that the cognitive abilities of the intervention group were significantly improved at the end of the intervention as well as at the end of the follow-up compared to the control group. The results of the current study suggest that the motor-cognitive intervention investigators used significantly improved cognitive function in older adults with MCI and was easy for older adults to master, and that it was a good intervention for cognitive function in older adults with MCI in the Chinese community.


Eligibility criteria: Inclusion Criteria:

* Age ≥65 years old;
* The screening results were mild cognitive impairment;
* Those who have the ability to walk independently or use auxiliary tools and can ·Communicate with each other normally;
* Informed consent, willing to participate in the researcher.

Exclusion Criteria:

* People with mental disorders;
* Patients with serious organ diseases, such as kidney and heart failure;
* People with mobility disabilities.

Primary outcomes:
measure: Generalized estimating equations for the two groups of MMSE scores at three time points
timeFrame: 2020.8-2021.2
measure: Between-group comparison of the MMSE scores of the two study groups at different time points
timeFrame: 2020.8-2021.2
measure: Intra-group comparison of MMSE scores between the two groups
timeFrame: 2020.8-2021.2
measure: Generalized estimating equations for MoCA scores for two groups of older people at three time points
timeFrame: 2020.8-2021.2
measure: Intergroup comparison of MoCA scores between the two study groups
timeFrame: 2020.8-2021.2
measure: Intra-group comparison of MoCA scores between the two groups of older people
timeFrame: 2020.8-2021.2
Secondary outcomes:
Other outcomes:
Locations:
city: Qingdao
country: China
facility: Jinxuan Cheng
state: Shandong
Study officials:
References: