Clinical trial NCT06270784: Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
Official title: Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Inferior Alveolar Nerve Injuries
Keywords: Mandibular nerve injuries, impacted teeth, tooth extraction
Lead sponsor: Marmara University
Sponsor class: OTHER
First posted: 2024-02-21
Enrollment: 46
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this clinical study was to compare the effects of traditional and orthodontic extraction methods on postoperative nerve damage in impacted third molars associated with the inferior alveolar nerve. The main question it aims to answer is:

-Does the orthodontic extraction method reduce the risk of nerve injury compared to traditional extraction?

Participants will:

* undergo either traditional or orthodontic extraction
* be monitored for postoperative paresthesia.

Researchers will compare traditional and orthodontic extraction methods to see if extraction methods affect postoperative nerve damage.

Detailed description: The extraction of an impacted mandibular third molar is one of the most frequently performed procedures by oral and maxillofacial surgeons. The close anatomical relationship between the root of an impacted mandibular third molar and the inferior alveolar nerve may result in inferior alveolar nerve damage. The incidence of inferior alveolar nerve injury during the removal of an impacted mandibular third molar ranges from 0.35% to 8.4%. In addition to radiographic analysis, various surgical techniques, such as coronectomy, have been proposed to reduce the incidence of inferior alveolar nerve injury.

The orthodontic extraction technique is an orthodontically supported surgical approach that reduces the risk of neurological complications that may occur in inferior alveolar nerve and facilitates the surgical removal of impacted mandibular third molars close to the mandibular canal, even if they are associated with cystic lesions.

The purpose of this study is to examine the effect of orthodontic extraction applied to minimize inferior alveolar nerve damage during the extraction of deeply impacted mandibular third molar teeth on postoperative nerve injury. For this purpose, the postoperative paresthesia findings of patients who underwent orthodontic extraction will be compared with those of those who underwent traditional extraction.

Eligibility criteria: Inclusion Criteria:

* Presence of indication for wisdom tooth extraction for reasons such as pericoronitis, pathological formation, orthodontic reasons, caries, etc.
* Mandibular impacted wisdom teeth close to the inferior alveolar nerve

Exclusion Criteria:

* Mandibular impacted wisdom tooth not close to inferior alveolar nerve
* Wisdom tooth whose apexification has not yet been completed
* Suspicion of a malignant pathological lesion
* Pathological lesion associated with inferior alveolar nerve
* Presence of an acute infection

Primary outcomes:
measure: 2-point discrimination test on the 7th day after surgery
timeFrame: A 2-point discrimination test will be performed before the extraction and 7 days after extraction in both groups.
Secondary outcomes:
measure: Visual Analog Score(VAS)
timeFrame: VAS will be evaluated on the 7th and 14th postoperative days and the 1st, 3rd, and 6th months after tooth extraction.
measure: 2-point discrimination test on the 14th days and the 1st, 3rd, and 6th months after extraction.
timeFrame: A 2-point discrimation test will be performed on the 14th days and the 1st, 3rd, and 6th months after extraction.
measure: Inferior alveolar nerve recovery
timeFrame: Inferior alveolar nerve recovery will be assessed on the 7th and 14th postoperative days and the 1st, 3rd, and 6th months after tooth extraction.
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Marmara University
state: Basibuyuk
Study officials:
References: