Clinical trial NCT05629650: Feasibility Study of Tai Chi for Cognitively Impaired Older Adults
Official title: Effects of 12-week Tai Chi Program on Physical Function, Depression, and Quality of Life Among Cognitively Impaired Older Adults: A Feasibility Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cognitive Impairment
Keywords: Tai Chi
cognitive impairment
dementia
Lead sponsor: Chungnam National University
Sponsor class: OTHER
Collaborators: name: National Research Foundation, Singapore
First posted: 2022-11-29
Enrollment: 41
Sex: ALL
Minimum age (years): 75
Maximum age (years): 90
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: two intervention groups (1) those with MCI (2) those with dementia
Primary purpose: PREVENTION

Brief summary: The goal of this clinical trial is to determine the feasibility of a 12-week program of Tai Chi for memory (TCM) among older adults with mild cognitive impairment (MCI) or dementia and to determine the effects of TCM on physical functioning, depression, and health-related QoL. Two experimental groups will be recruited for inclusion criteria of community-residing older adults with a diagnosis of either MCI or Dementia.

Detailed description: The purpose of the study are to determine the acceptability of a 12-week program of Tai Chi for memory (TCM) among older adults with mild cognitive impairment (MCI) or dementia; and to determine the effects of TCM on physical functioning, depression, and health-related QoL.

A quasi-experimental design was used with two groups classified according to the level of their cognitive impairment (MCI vs. Dementia).

Depression, health-related QoL, and physical functioning including grip strength, balance, flexibility, and mobility were measured before and after the 12-week TCM program.

Depression was measured using the Korean version of the Geriatric Depression Scale.

Health-related QoL was measured using the 12-item Short Form survey (SF-12). Grip strength was assessed using a digital hand dynamometer. Flexibility was assessed using the standard sit-and-reach test. Balance was measured using the one-leg-standing balance test. Mobility was assessed using the timed up and go test. Paired and independent t-tests will be used to compare the effects of TCM within and between groups.

Eligibility criteria: Inclusion Criteria:

* community-residing older adults aged 75 years or older,
* registered at the public dementia prevention centers for dementia screening by health professionals with the diagnosis of either MCI or dementia,
* Korean version of the Montreal Cognitive Assessment (MoCA-K) score of 22 or lower,
* agreed to participate in the Tai Chi program twice a week for 12 weeks.

Exclusion Criteria:

* participated in any formal regular exercise program during the previous 6 months, and

Primary outcomes:
measure: physical function-grip strength
timeFrame: changes from pretest to 12 week posttest scores
measure: physical function - flexibility
timeFrame: changes from pretest to 12 week posttest scores
measure: physical function - balance
timeFrame: changes from pretest to 12 week posttest scores
measure: physical function - mobility
timeFrame: changes from pretest to 12 week posttest scores
Secondary outcomes:
measure: emotional functioning - depression
timeFrame: changes from pretest to 12 week posttest scores
measure: Short Form Health Survey 12 (SF12)
timeFrame: changes from pretest to 12 week posttest scores
Other outcomes:
Locations:
city: Daejeon
country: Korea, Republic of
facility: Tai Chi for health institute
Study officials:
affiliation: Chungnam National University
name: Rhayun Song, PhD
role: PRINCIPAL_INVESTIGATOR
References: