Clinical trial NCT06621784: Core Stabilization Exercises in Patients with Knee Osteoarthritis
Official title: The Effect of Core Stabilization Exercises on Pain, Function, Balance, and Quadriceps Muscle Thickness in Patients with Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Exercise Training
Osteoarthritis, Knee
Core Stability
Muscle Thickness of the Quadriceps Femoris
Balance
Lead sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sponsor class: OTHER_GOV
First posted: 2024-10-01
Enrollment: 32
Sex: ALL
Minimum age (years): 50
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Exercise plays a key role in the treatment of knee osteoarthritis, but there is no clear evidence on which type of exercise is most effective. Recent studies highlight the benefits of core stabilization exercises for improving knee stability. This study aims to demonstrate the effects of adding core stabilization exercises to conventional exercise therapy for patients with knee osteoarthritis.

Detailed description: Knee osteoarthritis is becoming a significant public health problem with the aging population. While there is no definitive cure, exercise is the main approach to treatment. Various types of exercises are being studied for their effectiveness in osteoarthritis treatment, and recently, core stabilization exercises have been highlighted for their role in lower extremity pathologies. In this study, we aimed to investigate the effects of these exercises on pain, balance, quality of life, function, and quadriceps muscle thickness in patients with knee osteoarthritis.

This study was designed as a randomized controlled double-blind clinical trial. Thirty-two patients were randomly divided into two groups: a conventional exercise group and a conventional+core group. A total of 18 home exercise sessions, performed three times per week for six weeks, were planned.

Eligibility criteria: Inclusion Criteria:

* Diagnosis of bilateral stage II or III knee osteoarthritis according to the Kellgren and Lawrence grading system
* Aged between 50 and 65 years
* Having a complaint of knee pain for at least 6 months
* No systemic diseases that may hinder exercise (such as uncontrolled hypertension, cardiac arrhythmia, heart failure, neurological sequelae, joint deformities, malignancy, etc.)

Exclusion Criteria:

* Having received physical therapy in the last 6 months
* Having undergone knee injection in the last 6 months
* Having had knee surgery
* Morbid obesity
* Presence or history of malignancy
* Individuals with severe visual impairment
* Individuals with a history of neurological or vestibular diseases that could cause balance problems, or patients using medications that may affect balance
* Individuals with serious cardiac, respiratory, or uncontrolled metabolic diseases

Primary outcomes:
measure: Change in Knee Injury and Osteoarthritis Outcome Score total and subscale scores after a 6-week exercise program
timeFrame: Baseline and 1 week after the 6-week exercise program
Secondary outcomes:
measure: Change in single-leg stance test durations after a 6-week exercise program
timeFrame: Baseline and 1 week after the 6-week exercise program
measure: Change in quadriceps femoris muscle thickness after a 6-week exercise program
timeFrame: Baseline and 1 week after the 6-week exercise program
measure: Change in Visual Analog Scale at rest and during activity after a 6-week exercise program
timeFrame: Baseline and 1 week after the 6-week exercise program
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
state: Bahçelievler
Study officials:
affiliation: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
name: İrem Setenay ÖZKAN
role: PRINCIPAL_INVESTIGATOR
References: