Clinical trial NCT03864367: Mobile Weight-Support Therapy (MWeST) for Mobility After Geriatric Fracture
Official title: Mobile Weight-Support Therapy (MWeST) for Mobility After Geriatric Fracture
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Distal Femur Fracture
Lead sponsor: Washington University School of Medicine
Sponsor class: OTHER
First posted: 2019-03-06
Enrollment: 0
Sex: ALL
Minimum age (years): 55
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Study population is anyone 55 years of age and older with a distal femur fracture.

Brief summary: This is a two-year study proposal to assess feasibility of MWeST (Mobile Weight-Support Therapy) implementation after geriatric fracture and its effects on functional and patient-reported outcomes.

The goal of this study is to improve mobilization of geriatric lower extremity trauma patients, with the aim of improving overall functional and patient-reported outcomes while decreasing complications and readmissions. Almost 50% of the adult population in the United States has osteopenia or osteoporosis, with over 2 million fragility fractures per year and a projected $25 billion in costs by 2025. These patients are at high risk for readmission due to complications, and at increased risk of mortality with these complications. Sarcopenia, a generalized loss of skeletal muscle associated with aging, has also been associated with increased disability and increased risk of future fracture in these patients. The investigator's study aims to assess the value of weight-support therapy for geriatric patients with lower extremity trauma in improving their overall risk of future injury and disability.

Detailed description: The goal of this study is to improve mobilization of geriatric lower extremity trauma patients, with the aim of improving overall functional and patient-reported outcomes while decreasing complications and readmissions. Almost 50% of the adult population in the United States has osteopenia or osteoporosis, with over 2 million fragility fractures per year and a projected $25 billion in costs by 2025. These patients are at high risk for readmission due to complications, and at increased risk of mortality with these complications. Sarcopenia, a generalized loss of skeletal muscle associated with aging, has also been associated with increased disability and increased risk of future fracture in these patients. The investigator's study aims to assess the value of weight-support therapy for geriatric patients with lower extremity trauma in improving their overall risk of future injury and disability.

Eligibility criteria: Inclusion Criteria:

* 55 and older
* distal femur fracture
* able to walk prior to fracture

Exclusion Criteria:

* patients unable to walk without any assistive devices post-injury
* patients too medically unstable to participate in physical therapy

Primary outcomes:
measure: Walking with device
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Saint Louis
country: United States
facility: Washington University in St. Louis
state: Missouri
Study officials:
affiliation: Washington University School of Medicine
name: ANNA N MILLER, MD
role: PRINCIPAL_INVESTIGATOR
References: