Clinical trial NCT03398148: A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Participants With Moderately to Severely Active Ulcerative Colitis
Official title: A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Ulcerative Colitis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
PHASE3
Conditions: Ulcerative Colitis (UC)
Keywords: ABBV-066
BI 655066
Lead sponsor: AbbVie
Sponsor class: INDUSTRY
First posted: 2018-01-12
Enrollment: 1558
Sex: ALL
Minimum age (years): 16
Maximum age (years): 80
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2.

The objective of Sub-Study 2 is to evaluate the efficacy and safety of risankizumab compared to placebo in inducing clinical remission in subjects with moderately to severely active UC.


Eligibility criteria: Inclusion Criteria:

* Male or female aged \>=18 to \<= 80 years at the Baseline Visit. Where locally permissible, subjects 16 to \< 18 years of age who meet the definition of Tanner stage 5 for development at the Baseline Visit.
* Confirmed diagnosis of ulcerative colitis (UC) for at least 3 months prior to Baseline.
* Active UC as assessed by Adapted Mayo Score and Endoscopic Subscore.
* Demonstrated intolerance or inadequate response to conventional therapy and tofacitinib (not a biologic) and one or more biologic therapies.
* Females must be postmenopausal for more than 1 year or surgically sterile or practicing specific forms of birth control.

Exclusion Criteria:

* Participant with a current diagnosis of Crohn's disease (CD), inflammatory bowel disease-unclassified (IBD-U) or a history of radiation colitis or ischemic colitis.
* Participant receiving prohibited medications and treatment.
* Extent of inflammatory disease limited to the rectum as assessed by screening endoscopy.
* Participant with currently known complications of UC (e.g., megacolon).
* No known active Coronavirus Disease - 2019 (COVID-19) infection.

Primary outcomes:
measure: Sub-Study 1: Percentage of Participants Achieving Clinical Remission Per Adapted Mayo Score
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Clinical Remission Per Adapted Mayo Score
timeFrame: Week 12
Secondary outcomes:
measure: Sub-Study 1: Percentage of Participants Achieving Endoscopic Improvement
timeFrame: Week 12
measure: Sub-Study 1: Percentage of Participants Achieving Clinical Remission Per Full Mayo Score in Participants With a Full Mayo Score of 6 to 12 at Baseline
timeFrame: Week 12
measure: Sub-Study 1: Percentage of Participants Achieving Clinical Response Per Adapted Mayo Score
timeFrame: Week 12
measure: Sub-Study 1: Percentage of Participants Achieving Clinical Response Per Partial Adapted Mayo Score
timeFrame: Week 4
measure: Sub-Study 1: Percentage of Participants Achieving Endoscopic Remission
timeFrame: Week 12
measure: Sub-Study 1: Percentage of Participants With Hospitalization
timeFrame: Through Week 12
measure: Sub-Study 1: Percentage of Participants Achieving Histologic Endoscopic Mucosal Remission (HEMR)
timeFrame: Week 12
measure: Sub-Study 1: Change in Ulcerative Colitis Symptom Questionnaire (UC-SQ)
timeFrame: Baseline Through Week 12
measure: Sub-Study 1: Change in Inflammatory Bowel Disease Questionnaire (IBDQ)
timeFrame: Baseline Through Week 12
measure: Sub-Study 1: Change From Baseline in Short Form-36 (SF-36) - Physical Component
timeFrame: Baseline Through Week 12
measure: Sub-Study 1: Change From Baseline in Short Form-36 (SF-36) - Mental Component
timeFrame: Baseline through Week 12
measure: Sub-Study 1: Change in Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue)
timeFrame: Baseline Through Week 12
measure: Sub-Study 1: Percentage of Participants Undergoing Ulcerative Colitis (UC)-Related Surgeries
timeFrame: Through Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Clinical Response Per Adapted Mayo Score
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Endoscopic Improvement
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Histologic Endoscopic Mucosal Improvement (HEMI)
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Endoscopic Remission
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Clinical Response Per Partial Adapted Mayo Score at Week 4
timeFrame: Week 4
measure: Sub-Study 2: Percentage of Participants Achieving No Bowel Urgency
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving No Abdominal Pain
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving Histologic Endoscopic Mucosal Remission (HEMR): Endoscopy Subscore of 0 and Geboes Score < 2.0) at Week 12
timeFrame: Week 12
measure: Sub-Study 2: Change in Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue)
timeFrame: Baseline to Week 12
measure: Sub-Study 2: Change in Inflammatory Bowel Disease Questionnaire (IBDQ) Total Score
timeFrame: Baseline to Week 12
measure: Sub-Study 2: Occurrence of UC-related Hospitalizations
timeFrame: Baseline Through Week 12
measure: Sub-Study 2: Percentage of Participants Achieving No Nocturnal Bowel Movements
timeFrame: Week 12
measure: Sub-Study 2: Percentage of Participants Achieving No Tenesmus
timeFrame: Week 12
measure: Sub-Study 2: Change in Number of Fecal Incontinence Episodes Per Week
timeFrame: Baseline to Week 12
measure: Sub-Study 2: Change in Number of Days Per Week With Sleep Interrupted Due to UC Symptoms
timeFrame: Baseline to Week 12
Other outcomes:
Locations:
city: Coronado
country: United States
facility: Southern California Res. Ctr. /ID# 169660
state: California
city: Irvine
country: United States
facility: Hoag Memorial Hosp Presbyterian /ID# 218348
state: California
city: La Jolla
country: United States
facility: UC San Diego Health System /ID# 160452
state: California
city: Los Alamitos
country: United States
facility: United Medical Doctors /ID# 158528
state: California
city: Los Angeles
country: United States
facility: Gastrointestinal Biosciences Clinical Trials, LLC /ID# 200931
state: California
city: San Francisco
country: United States
facility: UCSF Center for Colitis and Crohn's Disease /ID# 201210
state: California
city: West Hollywood
country: United States
facility: Cedars-Sinai Medical Center-West Hollywood /ID# 163851
state: California
city: Colorado Springs
country: United States
facility: Peak Gastroenterology Associates, PC /ID# 165841
state: Colorado
city: Lone Tree
country: United States
facility: Rocky Mountain Pediatric Gastroenterology /ID# 207174
state: Colorado
city: Hamden
country: United States
facility: Medical Research Center of CT /ID# 160311
state: Connecticut
city: New Haven
country: United States
facility: Yale Univ Digestive Diseases /ID# 213179
state: Connecticut
city: Clermont
country: United States
facility: South Lake Pain Institute, Inc /ID# 162878
state: Florida
city: Maitland
country: United States
facility: Ctr for Advanced Gastroenterol /ID# 202811
state: Florida
city: Miami
country: United States
facility: University of Miami /ID# 160471
state: Florida
city: Miami
country: United States
facility: Coral Research Clinic /ID# 158584
state: Florida
city: Miami
country: United States
facility: South Florida Research Ph I-IV, Inc. /ID# 161848
state: Florida
city: Naples
country: United States
facility: Gastroenterology Group Naples /ID# 165212
state: Florida
city: New Port Richey
country: United States
facility: Advanced Research Institute, Inc /ID# 161938
state: Florida
city: Orlando
country: United States
facility: Advent Health /ID# 160433
state: Florida
city: Orlando
country: United States
facility: Endoscopic Research, Inc. /ID# 206711
state: Florida
city: Orlando
country: United States
facility: Omega Research Group /ID# 203059
state: Florida
city: Sweetwater
country: United States
facility: Lenus Research & Medical Group /ID# 169730
state: Florida
city: Tampa
country: United States
facility: Clinical Research Trials of Florida, Inc. /ID# 201783
state: Florida
city: Tampa
country: United States
facility: AdventHealth Tampa /ID# 170503
state: Florida
city: Macon
country: United States
facility: Gastroenterology Associates of Central Georgia, LLC /ID# 160523
state: Georgia
city: Suwanee
country: United States
facility: Atlanta Gastroenterology Spec /ID# 161372
state: Georgia
city: Chicago
country: United States
facility: The University of Chicago Medical Center /ID# 160521
state: Illinois
city: Oak Lawn
country: United States
facility: DM Clinical Research/Southwest /ID# 165012
state: Illinois
city: Indianapolis
country: United States
facility: Indiana University /ID# 167252
state: Indiana
city: Kansas City
country: United States
facility: Univ Kansas Med Ctr /ID# 226602
state: Kansas
city: Topeka
country: United States
facility: Cotton-O'Neil Clinical Res Ctr /ID# 160412
state: Kansas
city: Louisville
country: United States
facility: Robley Rex VA Medical Center /ID# 218648
state: Kentucky
city: Houma
country: United States
facility: Houma Digestive Health Special /ID# 158317
state: Louisiana
city: New Orleans
country: United States
facility: Delricht Research /ID# 206815
state: Louisiana
city: New Orleans
country: United States
facility: Nola Research Works, LLC /ID# 161368
state: Louisiana
city: Shreveport
country: United States
facility: Louisana Research Center, LLC /ID# 201204
state: Louisiana
city: Boston
country: United States
facility: Massachusetts General Hospital - Crohn's and Colitis Center /ID# 164255
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 158524
state: Michigan
city: Chesterfield
country: United States
facility: Clin Res Inst of Michigan, LLC /ID# 160327
state: Michigan
city: Rochester
country: United States
facility: Mayo Clinic - Rochester /ID# 200458
state: Minnesota
city: Omaha
country: United States
facility: Quality Clinical Research Inc. /ID# 167313
state: Nebraska
city: New York
country: United States
facility: Weill Cornell Medicine /ID# 165887
state: New York
city: New York
country: United States
facility: Columbia Univ Medical Center /ID# 161934
state: New York
city: New York
country: United States
facility: Lenox Hill Hospital /ID# 168470
state: New York
city: New York
country: United States
facility: Manhattan Clinical Research, LLC /ID# 211805
state: New York
city: North Massapequa
country: United States
facility: DiGiovanna Institute for Medical Education & Research /ID# 171129
state: New York
city: Rochester
country: United States
facility: University of Rochester Medical Center /ID# 161664
state: New York
city: Charlotte
country: United States
facility: Atrium Health Carolinas Medical Center /ID# 158512
state: North Carolina
city: Greenville
country: United States
facility: Carolina Research /ID# 201090
state: North Carolina
city: Fargo
country: United States
facility: Plains Clinical Research Center, LLC /ID# 169732
state: North Dakota
city: Cleveland
country: United States
facility: Cleveland Clinic Main Campus /ID# 209232
state: Ohio
city: Columbus
country: United States
facility: The Ohio State University /ID# 164714
state: Ohio
city: Columbus
country: United States
facility: Optimed Research, Ltd. /ID# 167113
state: Ohio
city: Mentor
country: United States
facility: Great Lakes Gastroenterology Research, LLC /ID# 201777
state: Ohio
city: Sylvania
country: United States
facility: ProMedica Physicians Digestive Healthcare /ID# 215623
state: Ohio
city: Oklahoma City
country: United States
facility: Digestive Disease Specialists /ID# 170779
state: Oklahoma
city: Tulsa
country: United States
facility: Adult Gastroenterology Associates - Gen 1 Research /ID# 208867
state: Oklahoma
city: Hershey
country: United States
facility: Penn State Milton S. Hershey Medical Center /ID# 223563
state: Pennsylvania
city: Philadelphia
country: United States
facility: University of Pennsylvania /ID# 166266
state: Pennsylvania
city: Wyomissing
country: United States
facility: Digestive Disease Associates, LTD /ID# 232407
state: Pennsylvania
city: Greenville
country: United States
facility: Gastroenterology Associates, P.A. of Greenville /ID# 160472
state: South Carolina
city: Cordova
country: United States
facility: Gastro One /ID# 160418
state: Tennessee
city: Johnson City
country: United States
facility: East Tennessee Research Institute /ID# 168747
state: Tennessee
city: Nashville
country: United States
facility: Vanderbilt University Medical Center /ID# 160580
state: Tennessee
city: Baytown
country: United States
facility: Inquest Clinical Research /ID# 165685
state: Texas
city: Cedar Park
country: United States
facility: Texas Digestive Disease Consultants /ID# 209950
state: Texas
city: Cedar Park
country: United States
facility: GI Alliance /ID# 209798
state: Texas
city: Garland
country: United States
facility: DHAT Research Institute /ID# 158226
state: Texas
city: Houston
country: United States
facility: Vilo Research Group Inc /ID# 207656
state: Texas
city: Houston
country: United States
facility: CliniCore International, LLC /ID# 158218
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine - Baylor Medical Center /ID# 158221
state: Texas
city: Houston
country: United States
facility: Precision Research Institute, LLC /ID# 201351
state: Texas
city: Houston
country: United States
facility: Centex Studies, Inc. - Houston /ID# 201222
state: Texas
city: Lubbock
country: United States
facility: Caprock Gastro Research, LLC /ID# 215432
state: Texas
city: San Antonio
country: United States
facility: Clinical Associates in Research Therapeutics of America, LLC /ID# 161376
state: Texas
city: San Antonio
country: United States
facility: Southern Star Research Institute, LLC /ID# 168776
state: Texas
city: Temple
country: United States
facility: Baylor Scott & White Center for Diagnostic Medicine /ID# 204130
state: Texas
city: Tyler
country: United States
facility: Tyler Research Institute, LLC /ID# 166800
state: Texas
city: Victoria
country: United States
facility: Gastro Health & Nutrition - Victoria /ID# 164321
state: Texas
city: Ogden
country: United States
facility: Advanced Research Institute /ID# 160480
state: Utah
city: Roanoke
country: United States
facility: Gastroenterology Consultants of Southwest Virginia /ID# 218143
state: Virginia
city: Seattle
country: United States
facility: Virginia Mason Medical Center /ID# 160466
state: Washington
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Gedyt /ID# 243423
state: Ciuadad Autonoma De Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Cemic /Id# 167782
state: Ciuadad Autonoma De Buenos Aires
city: Rosario
country: Argentina
facility: Hospital Provincial del Centenario /ID# 170898
state: Santa Fe
city: San Miguel de Tucuman
country: Argentina
facility: Sanatorio 9 de Julio /ID# 167780
state: Tucuman
city: Cordoba
country: Argentina
facility: Hospital Privado Univesitario /ID# 167779
city: St. Poelten
country: Austria
facility: Duplicate_Universitaetsklinikum St.Poelten /ID# 169048
state: Niederoesterreich
city: Linz
country: Austria
facility: Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 215320
state: Oberoesterreich
city: Graz
country: Austria
facility: Medizinische Universitaet Graz /ID# 169053
state: Steiermark
city: Vienna
country: Austria
facility: Medizinische Universitaet Wien /ID# 169050
state: Wien
city: Salzburg
country: Austria
facility: Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 200685
city: Brussels
country: Belgium
facility: Cliniques Universitaires de Bruxelles Hopital Erasme /ID# 200252
state: Bruxelles-Capitale
city: Woluwe-Saint-Lambert
country: Belgium
facility: UCL Saint-Luc /ID# 200039
state: Bruxelles-Capitale
city: Godinne
country: Belgium
facility: CHU UCL Namur - site Godinne /ID# 200254
state: Namur
city: Leuven
country: Belgium
facility: Universitair Ziekenhuis Leuven /ID# 170812
state: Vlaams-Brabant
city: Roeselare
country: Belgium
facility: AZ-Delta /ID# 200040
state: West-Vlaanderen
city: Bonheiden
country: Belgium
facility: Imelda Ziekenhuis /ID# 211100
city: Liege
country: Belgium
facility: CHU de Liege /ID# 200253
city: Liege
country: Belgium
facility: Groupe Sante CHC - Clinique du MontLegia /ID# 200250
city: Goiânia
country: Brazil
facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 157679
state: Goias
city: Curitiba
country: Brazil
facility: Hospital Nossa Senhora das Graças /ID# 157671
state: Parana
city: Porto Alegre
country: Brazil
facility: Hospital de Clinicas de Porto Alegre /ID# 157662
state: Rio Grande Do Sul
city: Botucatu
country: Brazil
facility: Upeclin Fmb - Unesp /Id# 157690
state: Sao Paulo
city: Ribeirão Preto
country: Brazil
facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP /ID# 157660
state: Sao Paulo
city: Santo André
country: Brazil
facility: Faculdade de Medicina do ABC /ID# 163995
state: Sao Paulo
city: Sao Jose Do Rio Preto
country: Brazil
facility: Kaiser Clinica e Hospital Dia /ID# 157680
state: Sao Paulo
city: Plovdiv
country: Bulgaria
facility: UMHAT Kaspela EOOD /ID# 200797
city: Sliven
country: Bulgaria
facility: MHAT Hadzhi Dimitar /ID# 207945
city: Sofia
country: Bulgaria
facility: Second MHAT Sofia /ID# 200799
city: Sofia
country: Bulgaria
facility: UMHAT Sveti Ivan Rilski /ID# 210797
city: Sofia
country: Bulgaria
facility: UMHAT Tsaritsa Joanna - ISUL /ID# 209977
city: Calgary
country: Canada
facility: University of Calgary /ID# 169111
state: Alberta
city: Edmonton
country: Canada
facility: Allen Whey Khye Lim Professional Corporation /ID# 169767
state: Alberta
city: Edmonton
country: Canada
facility: Covenant Health /ID# 169114
state: Alberta
city: New Westminster
country: Canada
facility: Fraser Clinical Trials Inc /ID# 169102
state: British Columbia
city: Victoria
country: Canada
facility: Percuro Clinical Research, Ltd /ID# 169109
state: British Columbia
city: London
country: Canada
facility: London Health Sciences Center- University Hospital /ID# 169103
state: Ontario
city: North Bay
country: Canada
facility: Scott Shulman Medicine Professional Corporation /ID# 169113
state: Ontario
city: Vaughan
country: Canada
facility: Toronto Digestive Disease Asso /ID# 169106
state: Ontario
city: Lévis
country: Canada
facility: Hotel Dieu de Levis /ID# 214378
state: Quebec
city: Montreal
country: Canada
facility: CIUSSS de l'est de l'Ile-de-Montreal - Hopital Maisonneuve-Rosemont /ID# 169108
state: Quebec
city: Montreal
country: Canada
facility: Royal Victoria Hospital / McGill University Health Centre /ID# 169104
state: Quebec
city: Victoria
country: Chile
facility: Servicio de Salud Araucanía Norte Hospital Victoria /ID# 213151
state: Araucania
city: Santiago
country: Chile
facility: Complejo Asistencial Dr. Sotero del Rio /ID# 169385
state: Region Metropolitana Santiago
city: Santiago
country: Chile
facility: Servicio de Salud Occidente Hospital San Juan de Dios /ID# 171125
state: Region Metropolitana Santiago
city: Concepción
country: Chile
facility: Hospital Guillermo Grant Benavente de Concepción /ID# 210761
city: Talcahuano
country: Chile
facility: Hospital Las Higueras /ID# 167093
city: Hefei
country: China
facility: The First Affiliated Hospital of Anhui Medical University /ID# 211228
state: Anhui
city: Beijing
country: China
facility: Beijing Friendship Hospital /ID# 211066
state: Beijing
city: Guangzhou
country: China
facility: The Sixth Affiliated Hosp Sun /ID# 211231
state: Guangdong
city: Shijiazhuang
country: China
facility: The Second Hospital of Hebei Medical University /ID# 213018
state: Hebei
city: Wuhan
country: China
facility: Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 211071
state: Hubei
city: Wuhan
country: China
facility: Tongji Hospital Tongji Medical College of HUST /ID# 211072
state: Hubei
city: Wuhan
country: China
facility: Renmin Hospital of Wuhan University /ID# 212868
state: Hubei
city: Huaian
country: China
facility: Huai'an First People's Hospital /ID# 239196
state: Jiangsu
city: Nanjing
country: China
facility: Nanjing Drum Tower Hospital /ID# 227439
state: Jiangsu
city: Nanjing
country: China
facility: Jiangsu Province Hospital /ID# 211232
state: Jiangsu
city: Wuxi
country: China
facility: Wuxi People's Hospital /ID# 218798
state: Jiangsu
city: Nanchang
country: China
facility: The First Affiliated Hospital of Nanchang University /ID# 212183
state: Jiangxi
city: Changchun
country: China
facility: The First Hospital of Jilin University /ID# 212278
state: Jilin
city: Yinchuan City
country: China
facility: General Hospital of Ningxia Medical University /ID# 213911
state: Ningxia
city: Xi'an
country: China
facility: Xijing Hospital /ID# 211639
state: Shaanxi
city: Xi'an
country: China
facility: Tangdu Hospital of The Fourth Military Medical University, PLA /ID# 215504
state: Shaanxi
city: Pudong New District
country: China
facility: Shanghai East Hospital /ID# 218791
state: Shanghai
city: Shanghai
country: China
facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 210962
state: Shanghai
city: Shanghai
country: China
facility: Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 211233
state: Shanghai
city: Shanghai
country: China
facility: Shanghai General Hospital /ID# 226190
state: Shanghai
city: Chengdu
country: China
facility: West China Hospital, Sichuan University /ID# 211276
state: Sichuan
city: Hangzhou
country: China
facility: The second Affiliated hospital of Zhejiang University school of Medicine /ID# 211025
state: Zhejiang
city: Hangzhou
country: China
facility: Sir Run Run Shaw Hospital,Meical School Zhejiang University /ID# 211064
state: Zhejiang
city: Changsha
country: China
facility: The Second Xiangya Hospital of Central South University /ID# 211198
city: Shenyang
country: China
facility: Shengjing Hospital of China Medical University /ID# 211646
city: Monteria
country: Colombia
facility: Oncomédica SAS /ID# 206937
state: Cordoba
city: Medellin
country: Colombia
facility: Hospital Universitario San Vic /ID# 171490
city: Zagreb
country: Croatia
facility: Clinical Hospital Dubrava /ID# 157475
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Klinicki bolnicki centar Zagreb /ID# 157471
state: Grad Zagreb
city: Zagreb
country: Croatia
facility: Klinicki bolnicki centar Zagreb /ID# 201917
state: Grad Zagreb
city: Osijek
country: Croatia
facility: Klinicki bolnicki centar Osijek /ID# 157472
state: Osjecko-baranjska Zupanija
city: Split
country: Croatia
facility: Klinicki bolnicki centar Split /ID# 157473
state: Splitsko-dalmatinska Zupanija
city: Brno
country: Czechia
facility: Fakultni nemocnice u sv. Anny v Brne /ID# 239157
city: Ceske Budejovice
country: Czechia
facility: Nemocnice Ceske Budejovice a.s. /ID# 225226
city: Hradec Kralove
country: Czechia
facility: Hepato-Gastroenterologie HK, s.r.o. /ID# 163395
city: Ostrava
country: Czechia
facility: Fakultni nemocnice Ostrava /ID# 225567
city: Copenhagen NV
country: Denmark
facility: Bispebjerg and Frederiksberg Hospital /ID# 208945
state: Hovedstaden
city: Hvidovre
country: Denmark
facility: Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 202266
state: Hovedstaden
city: Roskilde
country: Denmark
facility: Sjællands Universitetshospital /ID# 200033
state: Sjælland
city: Odense C
country: Denmark
facility: Odense University Hospital /ID# 205602
state: Syddanmark
city: Alexandria
country: Egypt
facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 200848
city: Alexandria
country: Egypt
facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 226793
city: Alexandria
country: Egypt
facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 226794
city: Cairo
country: Egypt
facility: Air Force Specialized Hospital /ID# 170986
city: Menoufiya
country: Egypt
facility: National Liver Institute /ID# 171040
city: Nice
country: France
facility: Chu de Nice-Hopital L'Archet Ii /Id# 171577
state: Alpes-Maritimes
city: Marseille
country: France
facility: APHM - Hopital Nord /ID# 225825
state: Bouches-du-Rhone
city: Pessac
country: France
facility: CHU Bordeaux - Hopital Haut Leveque /ID# 171579
state: Gironde
city: Montpellier Cedex 5
country: France
facility: CHU Montpellier - Hôpital Saint Eloi /ID# 223779
state: Herault
city: Clichy
country: France
facility: Hopital Beaujon /ID# 200092
state: Ile-de-France
city: Neuilly Sur Seine
country: France
facility: Centre Médico Chirurgical Ambroise Paré Hartmann /ID# 249860
state: Ile-de-France
city: St. Priest En Jarez
country: France
facility: CHU de SAINT ETIENNE - Hopital Nord /ID# 171580
state: Loire
city: Vandoeuvre-les-Nancy
country: France
facility: CHRU Nancy - Hopitaux de Brabois /ID# 200095
state: Meurthe-et-Moselle
city: Amiens CEDEX 1
country: France
facility: CHU Amiens-Picardie Site Sud /ID# 171576
state: Somme
city: Nantes
country: France
facility: Clinique Jules Verne /ID# 240976
city: Freiburg
country: Germany
facility: Universitaetsklinikum Freiburg /ID# 162034
state: Baden-Wuerttemberg
city: Heidelberg
country: Germany
facility: Praxis fuer Gastroenterologie /ID# 166152
state: Baden-Wuerttemberg
city: Mannheim
country: Germany
facility: Universitatsklinikum Mannheim /ID# 162035
state: Baden-Wuerttemberg
city: Ulm
country: Germany
facility: Universitaetsklinikum Ulm /ID# 164992
state: Baden-Wuerttemberg
city: Erlangen
country: Germany
facility: Universitaetsklinikum Erlangen /ID# 159354
state: Bayern
city: Grevenbroich
country: Germany
facility: Praxiszentrum fuer Gastroenterologie /ID# 219069
state: Nordrhein-Westfalen
city: Köln
country: Germany
facility: Universitaetsklinikum Koeln /ID# 164991
state: Nordrhein-Westfalen
city: Kiel
country: Germany
facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 159360
state: Schleswig-Holstein
city: Berlin
country: Germany
facility: Gastroenterologische Spezialpraxis am Wittenbergplatz /ID# 219145
city: Berlin
country: Germany
facility: MVZ fuer Gastroenterlogie am Bayerischen Platz /ID# 159361
city: Berlin
country: Germany
facility: Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 210510
city: Berlin
country: Germany
facility: DRK Kliniken Berlin Westend /ID# 166153
city: Braunschweig
country: Germany
facility: Stadtisches Klinikum Braunschweig /ID# 163687
city: Frankfurt am Main
country: Germany
facility: Agaplesion Markus Krankenhaus /ID# 159356
city: Kassel
country: Germany
facility: Gastroenterologie Opernstrasse /ID# 163683
city: Leipzig
country: Germany
facility: EUGASTRO GmbH /ID# 219070
city: Lueneburg
country: Germany
facility: Klinikum Lueneburg /ID# 163685
city: Minden
country: Germany
facility: Gastroenterologische Gemeinschaftspraxis Minden /ID# 162033
city: München
country: Germany
facility: LMU Klinikum Campus Grosshadern /ID# 210481
city: Regensburg
country: Germany
facility: Universitaetsklinikum Regensburg /ID# 163686
city: Athens
country: Greece
facility: General Hospital of Athens Ippokratio /ID# 229189
state: Attiki
city: Athens
country: Greece
facility: General Hospital of Athens Laiko /ID# 206440
state: Attiki
city: Athens
country: Greece
facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 170915
state: Attiki
city: Piraeus
country: Greece
facility: Tzaneio general hospital of Piraeus /ID# 206439
state: Attiki
city: Heraklion
country: Greece
facility: University General Hospital of Heraklion PA.G.N.I /ID# 165216
state: Kriti
city: Athens
country: Greece
facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 217480
city: Pireaus
country: Greece
facility: General Hospital of Nikaia-Piraeus "Agios Panteleimon"- general hospital dytikis /ID# 165218
city: Thessaloniki
country: Greece
facility: Theageneio Anticancer Hospital /ID# 165217
city: Be'er Sheva
country: Israel
facility: Soroka University Medical Center /ID# 171100
state: HaDarom
city: Ramat Gan
country: Israel
facility: The Chaim Sheba Medical Center /ID# 211278
state: Tel-Aviv
city: Jerusalem
country: Israel
facility: Hadassah Medical Center-Hebrew University /ID# 171099
state: Yerushalayim
city: Haifa
country: Israel
facility: Rambam Health Care Campus /ID# 171103
city: Jerusalem
country: Israel
facility: Shaare Zedek Medical Center /ID# 163544
city: Petakh Tikva
country: Israel
facility: Rabin Medical Center /ID# 167403
city: Catanzaro
country: Italy
facility: University of Catanzaro /ID# 200125
state: Calabria
city: Bologna
country: Italy
facility: Ospedale Sant Orsola Malpighi /ID# 155611
state: Emilia-Romagna
city: Genoa
country: Italy
facility: Ospedale Policlinico San Martino /ID# 164031
state: Genova
city: Rome
country: Italy
facility: Fondazione Policlinico Universitario Campus Bio-Medico di Roma /ID# 163992
state: Lazio
city: Rome
country: Italy
facility: Azienda Ospedaliera San Camillo Forlanini /ID# 155612
state: Lazio
city: Rome
country: Italy
facility: Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 171226
state: Lazio
city: Rho
country: Italy
facility: ASST Rhodense/Presidio Ospedaliero di Rho /ID# 211449
state: Milano
city: Rozzano
country: Italy
facility: Istituto Clinico Humanitas /ID# 155610
state: Milano
city: Rome
country: Italy
facility: Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 158018
state: Roma
city: Negrar
country: Italy
facility: IRCCS Ospedale Sacro Cuore Don Calabria /ID# 164041
state: Verona
city: Catania
country: Italy
facility: A.O. Per L'Emergenza Cannizzaro /ID# 164036
city: Milano
country: Italy
facility: ASST Fatebenefratelli Sacco-Ospedale Sacco /ID# 155607
city: Milano
country: Italy
facility: ASST Grande Ospedale Metropolitano Niguarda /ID# 170947
city: Modena
country: Italy
facility: Azienda Ospedaliero-Universitaria di Modena /ID# 201819
city: Rome
country: Italy
facility: UOC Medicina Interna e Gastroe /ID# 155608
city: Nagakute-shi
country: Japan
facility: Aichi Medical University Hospital /ID# 164332
state: Aichi
city: Nagoya shi
country: Japan
facility: Nagoya City University Hospital /ID# 164331
state: Aichi
city: Nagoya-shi
country: Japan
facility: Daido Clinic /ID# 211479
state: Aichi
city: Nagoya-shi
country: Japan
facility: Nagoya University Hospital /ID# 164271
state: Aichi
city: Toyoake-shi
country: Japan
facility: Fujita Health University Hospital /ID# 164261
state: Aichi
city: Hirosaki-shi
country: Japan
facility: National Hospital Organization Hirosaki General Medical Center /ID# 164252
state: Aomori
city: Abiko-shi
country: Japan
facility: Tokatsu Tsujinaka Hospital /ID# 164438
state: Chiba
city: Chiba-shi
country: Japan
facility: Chiba University Hospital /ID# 209632
state: Chiba
city: Kashiwa-shi
country: Japan
facility: Tsujinaka Hospital Kashiwanoha /ID# 208964
state: Chiba
city: Sakura-shi
country: Japan
facility: Toho University Sakura Medical Center /ID# 164254
state: Chiba
city: Chikushino-shi
country: Japan
facility: Fukuoka University Chikushi Hospital /ID# 209055
state: Fukuoka
city: Fukuoka-shi
country: Japan
facility: Saiseikai Fukuoka Genaral Hospital /ID# 225639
state: Fukuoka
city: Fukuoka-shi
country: Japan
facility: Fukuoka University Hospital /ID# 226189
state: Fukuoka
city: Kurume-shi
country: Japan
facility: Kurume University Hospital /ID# 164427
state: Fukuoka
city: Gifu-shi
country: Japan
facility: Gifu University Hospital /ID# 208081
state: Gifu
city: Ogaki-shi
country: Japan
facility: Ogaki Municipal Hospital /ID# 226010
state: Gifu
city: Takasaki-shi
country: Japan
facility: National Hospital Organization Takasaki General Medical Center /ID# 164437
state: Gunma
city: Fukuyama-shi
country: Japan
facility: NHO Fukuyama Medical Center /ID# 164439
state: Hiroshima
city: Hiroshima-shi
country: Japan
facility: Hiroshima University Hospital /ID# 164426
state: Hiroshima
city: Asahikawa-shi
country: Japan
facility: Asahikawa Medical University Hospital /ID# 164433
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 164251
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo Medical University Hospital /ID# 164432
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo IBD Clinic /ID# 225923
state: Hokkaido
city: Sapporo-shi
country: Japan
facility: Sapporo Higashi Tokushukai Hospital /ID# 208488
state: Hokkaido
city: Kobe-shi
country: Japan
facility: Aoyama Clinic /ID# 164425
state: Hyogo
city: Nishinomiya-shi
country: Japan
facility: Hyogo Medical University Hospital /ID# 164424
state: Hyogo
city: Kanazawa-shi
country: Japan
facility: Kanazawa University Hospital /ID# 169224
state: Ishikawa
city: Kagoshima-shi
country: Japan
facility: Sameshima Hospital /ID# 211181
state: Kagoshima
city: Isehara-shi
country: Japan
facility: Tokai University Hospital /ID# 209204
state: Kanagawa
city: Kamakura-shi
country: Japan
facility: Gokeikai Ofuna Chuo Hospital /ID# 169300
state: Kanagawa
city: Kawasaki-shi
country: Japan
facility: St. Marianna University Hospital /ID# 226728
state: Kanagawa
city: Sagamihara-shi
country: Japan
facility: Kitasato University Hospital /ID# 169226
state: Kanagawa
city: Yokohama-shi
country: Japan
facility: Colo-proctology Center Matsushima Clinic /ID# 225914
state: Kanagawa
city: Yokohama-shi
country: Japan
facility: Showa University Fujigaoka Hospital /ID# 209555
state: Kanagawa
city: Tsu-shi
country: Japan
facility: Mie University Hospital /ID# 203633
state: Mie
city: Yokkaichi-shi
country: Japan
facility: Yokkaichi Hazu Medical Center /ID# 164441
state: Mie
city: Sendai-shi
country: Japan
facility: Tohoku University Hospital /ID# 164430
state: Miyagi
city: Nagasaki-shi
country: Japan
facility: Nagasaki University Hospital /ID# 202674
state: Nagasaki
city: Kashihara-shi
country: Japan
facility: Nara Medical University Hospital /ID# 169225
state: Nara
city: Osaka-shi
country: Japan
facility: Kinshukai Infusion Clinic /ID# 226747
state: Osaka
city: Takatsuki-shi
country: Japan
facility: Osaka Medical and Pharmaceutical University Hospital /ID# 226035
state: Osaka
city: Saga-shi
country: Japan
facility: Saga University Hospital /ID# 209396
state: Saga
city: Saitama-shi
country: Japan
facility: Tokitokai Tokito clinic /ID# 164253
state: Saitama
city: Otsu-shi
country: Japan
facility: Shiga University of Medical Science Hospital /ID# 164440
state: Shiga
city: Hamamatsu-shi
country: Japan
facility: Hamamatsu University Hospital /ID# 226727
state: Shizuoka
city: Hamamatsu-shi
country: Japan
facility: Matsuda Hospital /ID# 226616
state: Shizuoka
city: Sunto-gun
country: Japan
facility: NHO Shizuoka Medical Center /ID# 164435
state: Shizuoka
city: Bunkyo-ku
country: Japan
facility: Tokyo Medical And Dental University Hospital /ID# 164258
state: Tokyo
city: Chuo-ku
country: Japan
facility: St.Luke's International Hospital /ID# 225822
state: Tokyo
city: Hachioji-shi
country: Japan
facility: Tokai University Hachioji Hospital /ID# 226899
state: Tokyo
city: Itabashi-ku
country: Japan
facility: Teikyo University Hospital /ID# 225588
state: Tokyo
city: Minato-ku
country: Japan
facility: The Jikei University Hospital /ID# 164434
state: Tokyo
city: Minato-ku
country: Japan
facility: Kitasato University Kitasato Institute Hospital /ID# 164256
state: Tokyo
city: Mitaka-shi
country: Japan
facility: Kyorin University Hospital /ID# 164259
state: Tokyo
city: Shinagawa-ku
country: Japan
facility: NTT Medical Center Tokyo /ID# 225587
state: Tokyo
city: Shinjuku-ku
country: Japan
facility: Keio University Hospital /ID# 203629
state: Tokyo
city: Wakayama-shi
country: Japan
facility: Japanese Red Cross Wakayama Medical Center /ID# 171195
state: Wakayama
city: Wakayama-shi
country: Japan
facility: Wakayama Medical University Hospital /ID# 169487
state: Wakayama
city: Yamagata-shi
country: Japan
facility: Yamagata University Hospital /ID# 171474
state: Yamagata
city: Shunan-shi
country: Japan
facility: Tokuyama Central Hospital /ID# 226011
state: Yamaguchi
city: Guri
country: Korea, Republic of
facility: Hanyang University Gurihospital /ID# 158702
state: Gyeonggido
city: Seongnam si
country: Korea, Republic of
facility: CHA University Bundang Medical Center /ID# 158710
state: Gyeonggido
city: Suwon
country: Korea, Republic of
facility: The Catholic University of Korea, ST. Vincent's Hospital /ID# 158706
state: Gyeonggido
city: Seoul
country: Korea, Republic of
facility: Kangbuk Samsung Hospital /ID# 158707
state: Seoul Teugbyeolsi
city: Seoul
country: Korea, Republic of
facility: Yonsei University Health System Severance Hospital /ID# 158701
state: Seoul Teugbyeolsi
city: Busan
country: Korea, Republic of
facility: Inje University Haeundae Hospital /ID# 203028
city: Busan
country: Korea, Republic of
facility: Dong-A University Hospital /ID# 158705
city: Busan
country: Korea, Republic of
facility: Pusan National University Hospital /ID# 158711
city: Daegu
country: Korea, Republic of
facility: Yeungnam University Medical Center /ID# 158703
city: Daejeon
country: Korea, Republic of
facility: The Catholic University of Korea, Daejeon St.Mary's Hospital /ID# 242378
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center /ID# 158704
city: Riga
country: Latvia
facility: VCA Polyclinic Aura /ID# 163802
city: Riga
country: Latvia
facility: Pauls Stradins Clinical University Hospital /ID# 163803
city: Kaunas
country: Lithuania
facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 170714
city: Vilnius
country: Lithuania
facility: Vilnius University Hospital Santaros Klinikos /ID# 170614
city: Kelantan
country: Malaysia
facility: Universiti Sains Malaysia /ID# 221971
city: Cuernavaca
country: Mexico
facility: JM Research SC /ID# 203593
state: Morelos
city: Merida
country: Mexico
facility: Unidad de Atencion Medica e Investigacion en Salud /ID# 203595
state: Yucatan
city: Del. Benito Juárez
country: Mexico
facility: Health Pharma Professional Research S.A de C.V /ID# 203597
city: Amsterdam
country: Netherlands
facility: Academisch Medisch Centrum /ID# 157959
city: Tilburg
country: Netherlands
facility: Elisabeth Tweesteden Ziekenhuis /ID# 163767
city: Tauranga South
country: New Zealand
facility: Tauranga Hospital /ID# 212792
state: Bay Of Plenty
city: Christchurch
country: New Zealand
facility: Christchurch Hospital /ID# 205342
state: Canterbury
city: Hamilton
country: New Zealand
facility: Waikato Hospital /ID# 212789
state: Waikato
city: Newtown
country: New Zealand
facility: Wellington Regional Hospital /ID# 205343
state: Wellington
city: Lower Hutt
country: New Zealand
facility: Hutt Hospital /ID# 212786
city: Otago
country: New Zealand
facility: Dunedin Hospital /ID# 212790
city: Wroclaw
country: Poland
facility: Vistamed /ID# 210105
state: Dolnoslaskie
city: Bydgoszcz
country: Poland
facility: Vitamed Gałaj i Cichomski Sp.j. /ID# 213283
state: Kujawsko-pomorskie
city: Torun
country: Poland
facility: Gastromed Sp. z o.o /ID# 230978
state: Kujawsko-pomorskie
city: Krakow
country: Poland
facility: Centrum Medyczne Plejady /ID# 170633
state: Malopolskie
city: Warsaw
country: Poland
facility: WIP Warsaw IBD Point Profesor Kierkus /ID# 216102
state: Mazowieckie
city: Warszawa
country: Poland
facility: Centrum Zdrowia MDM /ID# 170597
state: Mazowieckie
city: Warszawa
country: Poland
facility: Panstwowy Instytut Medyczny MSWiA w Warszawie /ID# 170601
state: Mazowieckie
city: Warszawa
country: Poland
facility: Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Panstwowy Instytut Bada /ID# 170600
state: Mazowieckie
city: Warszawa
country: Poland
facility: NZOZ Vivamed Jadwiga Miecz /ID# 216307
state: Mazowieckie
city: Sopot
country: Poland
facility: Endoskopia Sp. z o.o. /ID# 170598
state: Pomorskie
city: Katowice
country: Poland
facility: NZOZ All-Medicus /ID# 170596
state: Slaskie
city: Tychy
country: Poland
facility: H-T. Centrum Medyczne - Endoterapia /ID# 230979
state: Slaskie
city: Guimaraes
country: Portugal
facility: Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 165580
state: Braga
city: Portimão
country: Portugal
facility: Centro Hospitalar Universitário do Algarve, EPE - Hospital de Portimão /ID# 166551
state: Faro
city: Santa Maria Da Feira
country: Portugal
facility: Centro Hospitalar de Entre Douro e Vouga /ID# 166052
state: Porto
city: Almada
country: Portugal
facility: Hospital Garcia de Orta, EPE /ID# 165583
city: Coimbra
country: Portugal
facility: Centro Hospitalar e Universitario de Coimbra, EPE /ID# 166054
city: Lisboa
country: Portugal
facility: Centro Hospitalar Universitario Lisboa Central, EPE - Hospital dos Capuchos /ID# 165582
city: Porto
country: Portugal
facility: Centro Hospitalar Universitario de Sao Joao, EPE /ID# 165581
city: Viseu
country: Portugal
facility: Centro Hosp de Tondela-Viseu /ID# 166053
city: Ponce
country: Puerto Rico
facility: Ponce Medical School Foundation /ID# 221244
city: San Juan
country: Puerto Rico
facility: San Jorge Children Hospital /ID# 166954
city: San Juan
country: Puerto Rico
facility: VA Caribbean Healthcare System /ID# 221245
city: Cluj-Napoca
country: Romania
facility: Clinica GASTRO MED SRL /ID# 224169
state: Cluj
city: Bucharest
country: Romania
facility: Sana Monitoring /Id# 224166
city: Bucharest
country: Romania
facility: Fundeni Clinical Institute /ID# 171264
city: Bucharest
country: Romania
facility: Fundeni Clinical Institute /ID# 224168
city: Timisoara
country: Romania
facility: Duplicate_Centrul Medical Tuculanu SRL /ID# 171268
city: Timișoara
country: Romania
facility: Cabinet Particular Policlinic Algomed /ID# 171266
city: Anzorey
country: Russian Federation
facility: Interdisctrict Multidisciplinary Hospital /ID# 203335
state: Kabardino-Balkarskaya Respublika
city: Nalchik
country: Russian Federation
facility: GBUZ Allergology and Immunology Center of Ministry of Health of Kabardino-Bal /ID# 233973
state: Kabardino-Balkarskaya Respublika
city: Kaliningrad
country: Russian Federation
facility: Immanuel Kant Baltic Federal University /ID# 204888
state: Kaliningradskaya Oblast
city: Kemerovo
country: Russian Federation
facility: Kuzbass Regional Clinical Hospital /ID# 165750
state: Kemerovskaya Oblast
city: Saint Petersburg
country: Russian Federation
facility: Uninova Medical Center /ID# 229216
state: Leningradskaya Oblast
city: Korolev
country: Russian Federation
facility: Arsvita Clinic /ID# 208946
state: Moskovskaya Oblast
city: Perm
country: Russian Federation
facility: Perm Clinical Center of the Federal Medical and Biological Agency /ID# 227457
state: Permskiy Kray
city: Sestroretsk
country: Russian Federation
facility: City Clinical Hospital #40 /ID# 203370
state: Sankt-Peterburg
city: Tyumen
country: Russian Federation
facility: Regional Clinical Hospital #1 /ID# 165754
state: Tyumenskaya Oblast
city: Dzerzhinskiy
country: Russian Federation
facility: Clinic of New Technologies of Medicine /ID# 203369
city: Moscow
country: Russian Federation
facility: First Moscow State Medical University n.a I.M. Sechenov /ID# 204978
city: Moscow
country: Russian Federation
facility: National Medical Research Center of Coloproctology n.a. A. N. Ryzhikh /ID# 203512
city: Moscow
country: Russian Federation
facility: Central Clinical Hospital RZHD Medicine /ID# 204917
city: Novosibirsk
country: Russian Federation
facility: Novosibirski Gastrocenter /ID# 229855
city: Pushkin
country: Russian Federation
facility: Euromedservice /ID# 204892
city: St. Petersburg
country: Russian Federation
facility: International Medical Center SOGAZ /ID# 206727
city: Ulyanovsk
country: Russian Federation
facility: Ulyanovsk Regional Clinical Hospital /ID# 203368
city: Belgrade
country: Serbia
facility: Clinical Hosp Center Zvezdara /ID# 200151
state: Beograd
city: Belgrade
country: Serbia
facility: University Clinical Center Serbia /ID# 200152
state: Beograd
city: Belgrade
country: Serbia
facility: Clin Hosp Ctr Bezanijska Kosa /ID# 202059
state: Beograd
city: Novi Sad
country: Serbia
facility: Clinical Center Vojvodina /ID# 156910
state: Vojvodina
city: Belgrade
country: Serbia
facility: Clinical Hospital Center Dr Dragisa Misovic - Dedinje /ID# 224926
city: Leskovac
country: Serbia
facility: General Hospital Leskovac /ID# 207226
city: Singapore
country: Singapore
facility: KL Ling Gastroenterology and Liver Clinic /ID# 205738
city: Banska Bystrica
country: Slovakia
facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 164347
city: Nitra
country: Slovakia
facility: KM Management, spol. s.r.o. /ID# 206602
city: Nove Zamky
country: Slovakia
facility: Fakultna nemocnica s poliklinikou Nove Zamky /ID# 224099
city: Presov
country: Slovakia
facility: GASTRO I., s.r.o. /ID# 164346
city: Ljubljana
country: Slovenia
facility: Univ Medical Ctr Ljubljana /ID# 210627
city: Bloemfontein
country: South Africa
facility: Farmovs (Pty) Ltd /Id# 207537
state: Free State
city: Johannesburg
country: South Africa
facility: Clinresco Centers /ID# 239824
state: Gauteng
city: CAPE TOWN Milnerton
country: South Africa
facility: Spoke Research Inc /ID# 229905
state: Western Cape
city: Cape Town
country: South Africa
facility: Allergy & Immunology (AIU) /ID# 171441
state: Western Cape
city: Cape Town
country: South Africa
facility: Dr JP Wright /ID# 171138
state: Western Cape
city: Cape Town
country: South Africa
facility: Private Practice Dr MN Rajabally /ID# 171137
state: Western Cape
city: Ferrol
country: Spain
facility: Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 159440
state: A Coruna
city: Gijon
country: Spain
facility: Hospital de Cabuenes /ID# 170748
state: Asturias
city: Sabadell
country: Spain
facility: Consorci Corporacio Sanitaria Parc Tauli Sabadell /ID# 159461
state: Barcelona
city: Majadahonda
country: Spain
facility: Hospital Universitario Puerta de Hierro, Majadahonda /ID# 159443
state: Madrid
city: Vigo
country: Spain
facility: Hospital Alvaro Cunqueiro CHUVI /ID# 167360
state: Pontevedra
city: Barcelona
country: Spain
facility: Hospital Clinic de Barcelona /ID# 159439
city: Cordoba
country: Spain
facility: Hospital Universitario Reina Sofia /ID# 167058
city: Madrid
country: Spain
facility: Hospital Universitario La Paz /ID# 159459
city: Pontevedra
country: Spain
facility: Complejo Hospitalario Universitario de Pontevedra /ID# 216182
city: Salamanca
country: Spain
facility: Hospital Universitario de Salamanca /ID# 159446
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Macarena /ID# 159968
city: Zaragoza
country: Spain
facility: Hospital Universitario Miguel Servet /ID# 159445
city: Alingsas
country: Sweden
facility: Alingsas lasarett /ID# 202074
state: Vastra Gotalands Lan
city: Molndal
country: Sweden
facility: Sahlgrenska University Hospital Molndal /ID# 202843
state: Vastra Gotalands Lan
city: Stockholm
country: Sweden
facility: Danderyds sjukhus AB /ID# 202035
city: Zurich
country: Switzerland
facility: Universitatsspital Zurich /ID# 202910
state: Zuerich
city: Bern
country: Switzerland
facility: Inselspital, Universitätsspital Bern /ID# 202911
city: Taichung
country: Taiwan
facility: Chung Shan Medical University Hospital /ID# 163651
city: Taichung
country: Taiwan
facility: China Medical University Hospital /ID# 160189
city: Taichung
country: Taiwan
facility: Taichung Veterans General Hospital /ID# 163649
city: Taipei City
country: Taiwan
facility: National Taiwan University Hospital /ID# 162187
city: Taipei
country: Taiwan
facility: Taipei Veterans General Hosp /ID# 163650
city: Taoyuan City
country: Taiwan
facility: Linkou Chang Gung Memorial Hospital /ID# 222877
city: Kadikoy
country: Turkey
facility: Acibadem Kozyatagi Hospital /ID# 213276
state: Istanbul
city: Melikgazi
country: Turkey
facility: Erciyes University Medical Fac /ID# 171291
state: Kayseri
city: Ankara
country: Turkey
facility: Ankara Univ Medical Faculty /ID# 167210
city: Battalgazi/malatya
country: Turkey
facility: Inonu Universitesi Turgut Ozal /ID# 203981
city: Bursa
country: Turkey
facility: Uludag University Medical Faculty /ID# 204182
city: Elazig
country: Turkey
facility: Fırat University Medical Facul /ID# 171292
city: Istanbul
country: Turkey
facility: Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty /ID# 167207
city: Istanbul
country: Turkey
facility: Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 171293
city: Sisli
country: Turkey
facility: Sisli Etfal Train & Res Hosp /ID# 171409
city: Ivano-frankivsk
country: Ukraine
facility: CNE Regional Clinical Hospital of Ivano-Frankivsk RC /ID# 203367
city: Kherson
country: Ukraine
facility: Municipal Nonprofit Enterprise Kherson city clinical hospital n.a. Y.Y. Karabel /ID# 224350
city: Kyiv
country: Ukraine
facility: Kyiv Municipal Clinical Hospital #18 /ID# 224348
city: Kyiv
country: Ukraine
facility: Medical Center "OK!Clinic+" /ID# 205482
city: Kyiv
country: Ukraine
facility: CNPE of Kyiv Regional Council Kyiv Regional Hospital /ID# 224343
city: Exeter
country: United Kingdom
facility: Royal Devon University Healthcare NHS Foundation Trust /ID# 157587
state: Devon
city: Southampton
country: United Kingdom
facility: University Hospital Southampton NHS Foundation Trust /ID# 210813
state: Hampshire
city: London
country: United Kingdom
facility: Barts Health NHS Trust /ID# 157590
state: London, City Of
city: Barnsley
country: United Kingdom
facility: Barnsley Hospital NHS Foundation Trust /ID# 202770
city: Cambridge
country: United Kingdom
facility: Cambridge University Hospitals NHS Foundation Trust /ID# 158040
city: Edinburgh
country: United Kingdom
facility: NHS Lothian /ID# 208802
city: Liverpool
country: United Kingdom
facility: Liverpool University Hospitals NHS Foundation Trust /ID# 203858
city: London
country: United Kingdom
facility: King's College Hospital NHS Foundation Trust /ID# 158766
city: Newcastle upon Tyne
country: United Kingdom
facility: The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 158041
city: Tooting
country: United Kingdom
facility: St George's University Hospitals NHS Foundation Trust /ID# 208378
Study officials:
affiliation: AbbVie
name: ABBVIE INC.
role: STUDY_DIRECTOR
References: