Clinical trial NCT05798065: Inpatient Endoscopy Procedure Planning Delays and Impact on Length of Stay and 30-day Readmission
Official title: Inpatient Endoscopy Procedure Planning Delays and Impact on Length of Stay and 30-day Readmission
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Inpatient Endoscopy Delay
Readmission
Prolonged Hospital Stay
Lead sponsor: Radboud University Medical Center
Sponsor class: OTHER
First posted: 2023-04-04
Enrollment: 3700
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult inpatients from all hospital departments undergoing endoscopy procedures. Patients will be selected via CTCue, with an admission based query that selects all adult patients with an admission of at least two days between 1-1-2014 and 1-12-2022 AND an endoscopic care activity.

Brief summary: Single center retrospective cohort study of all inpatient endoscopy procedures to asses factors associated with inpatient endoscopy delays and impact on length of stay and 30-day readmission

Detailed description: Background: Delays in inpatient endoscopy planning negatively influence the quality and accessibility of care. This may result in higher healthcare costs, negative health outcomes, and unnecessary readmissions and use of hospital beds. Additionally, prolonged hospital stay is associated with poorer health outcomes and risk of nosocomial infections, amongst others.

Objective: To asses factors associated with inpatient endoscopy delays and impact on length of stay and 30-day readmission

Study design: Single center retrospective cohort study of all inpatient endoscopy procedures (gastroscopy, colonoscopy, ERCP, sigmoidoscopy) during 2016-2022. Data will be identified and extracted using CTCue. Only pseudonymized data will be used. Inpatient endoscopy delay will be defined as the number of days between the planned date versus the actual date. Multivariable logistic regression models will be performed to assess factors associated with inpatient endoscopy delay.

Eligibility criteria: Inclusion Criteria:

* Adult patients (\>18 years)
* Clinical admission in any hospital department of at least two days during 1 January 2016 and 1 December 2022
* Endoscopic procedure during clinical admission, including gastroscopy, endoscopic retrograde cholangiopancreatography (ERCP), endoscopic ultrasound (EUS), flexible sigmoidoscopy, colonoscopy

Exclusion Criteria:

* Elective admission
* Procedure only for insertion of nasogastric or nasojejunal (feeding) tube without any other diagnostic or therapeutic aims

Primary outcomes:
measure: Rate of inpatient endoscopy delays (IED)
timeFrame: at endoscopic procedure
measure: Difference in type of endoscopic procedure between patients with and without IED
timeFrame: at endoscopic procedure
measure: Difference in type of sedation between patients with and without IED
timeFrame: at endoscopic procedure
Secondary outcomes:
measure: Median length of hospital stay
timeFrame: through study cohort period from 1 january 2016 until 31 december 2022
measure: rate of 30-day readmissions
timeFrame: up to 30 days
measure: Odds ratio of presence of inpatient endoscopy delays for risk of prolonged length of hospital stay and 30-day readmissions
timeFrame: from admission till 30 days after discharge
measure: Odds ratio of presence of inpatient endoscopy delays for risk of 30-day readmissions
timeFrame: from admission till 30 days after discharge
Other outcomes:
Locations:
city: Nijmegen
country: Netherlands
facility: Radboud university medical center
state: Gelderland
Study officials:
affiliation: Radboud University Medical Center
name: Peter Siersema, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: