Clinical trial NCT05223062: Medication Adherence in Psoriatic Arthritis
Official title: Self-Reported Medication Adherence in Patients With Psoriatic Arthritis: Influence of Illness Perception and Medication Beliefs
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Psoriatic Arthritis
Keywords: Psoriatic Arthritis
Medication Adherence
Lead sponsor: Bezmialem Vakif University
Sponsor class: OTHER
First posted: 2022-02-03
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients diagnosed with psoriatic arthritis having medication for at least 6 months

Brief summary: Psoriatic arthritis (PsA) is a chronic multisystemic disease requiring ordinary doctor visits and an adherence to medication. Evaluating the parameters affecting the medication adherence is essential for the efficacy of the treatment. To our knowledge no study has ever evaluated the factors affecting the medication adherence in patients with PsA so far.

Detailed description: Psoriatic arthritis (PsA) is a multisystemic disease requiring ordinary doctor visits and an adherence to medication. Due to its chronic nature treatment regimens lasts for the lifetime and that may affect the efficacy of the treatment. Although treatment with drugs is a biological intervention, medication adherence and eliminating the factors affecting it seems essential for treatment efficacy. To our knowledge no study has ever evaluated the factors affecting the medication adherence in patients with PsA so far. Our aim in this study is to evaluate the factors affecting the medication adherence in patients with PsA.

Eligibility criteria: Inclusion Criteria:

* Diagnosed with PsA according to CASPAR criteria
* Administering PsA medication for at least 6 moths
* Aged ≥18

Exclusion Criteria:

* Not having enough cognitive functions to understand and answer the questionnaires
* Having a psychiatric disorder
* Having a severe comorbidity (e.g. malignancy, stroke)

Primary outcomes:
measure: Disease activity in psoriatic arthritis (DAPSA)
timeFrame: 1 day
measure: Compliance-Questionnaire-Rheumatology (CQR)
timeFrame: 1 day
measure: The Brief Illness Perception Questionnaire (BIPQ)
timeFrame: 1 day
measure: The Beliefs About Medicines Questionnaire (BMQ)
timeFrame: 1 day
measure: Hospital Anxiety and Depression Scale (HADS)
timeFrame: 1 day
measure: The Psoriatic Arthritis Quality of Life (PsAQoL)
timeFrame: 1 day
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakif University
state: Fatih
Study officials:
References:
citation: Hromadkova L, Soukup T, Vlcek J. Quality of life and drug compliance: their interrelationship in rheumatic patients. J Eval Clin Pract. 2015 Oct;21(5):919-24. doi: 10.1111/jep.12399. Epub 2015 Jun 17.
citation: Tolu S, Rezvani A, Karacan I, Bugdayci D, Kucuk HC, Bucak OF, Aydin T. Self-Reported Medication Adherence in Patients With Ankylosing Spondylitis: The Role of Illness Perception and Medication Beliefs. Arch Rheumatol. 2020 Feb 7;35(4):495-505. doi: 10.46497/ArchRheumatol.2020.7732. eCollection 2020 Dec.