Clinical trial NCT06331091: Physiotherapy and Reaction Time in Hemophilia
Official title: The Effectiveness of Low Frequency Comprehensive Physiotherapy Combined With Home Exercise on Joint Health, Frequency of Hemartrosis, Dynamic Balance and Reaction Time in Hemophilic Arthropthy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hemophilia Arthropathy
Keywords: hemophilia
physiotherapy
exercise
reaction time
joint health
arthropathy
Lead sponsor: Yuzuncu Yıl University
Sponsor class: OTHER
First posted: 2024-03-26
Enrollment: 21
Sex: MALE
Minimum age (years): 10
Maximum age (years): 32
Standard ages: CHILD
ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomised controlled study
Primary purpose: TREATMENT

Brief summary: This randomised controlled study was conducted to investigate the comprehensive physiotherapy combined with home exercises on individuals with hemophilic arthropathy in the lower extremity. There are two groups in the study: home exercises and comprehensive physiotherapy combined with home exercises. Is physiotherapy combined with home exercises superior to home exercises on joint health, bleeding frequency, reaction time, dynamic balance, muscle strength? The aim of this study is to increase the compliance of hemophilic individuals to physiotherapy and adapt home exercises to their lives with weekly sessions.

Detailed description: Introduction: The positive effects of physiotherapy and exercise on joint health, frequency of hemartrosis (FoH) in patient with hemophilic arhropathy (PwHA) are well explained in the literature. However, adaptation problems to physiotherapy sessions (usually 3 times a week) may cause PwHA to ignore the need for therapy. It may be more beneficial for PwHA to adapt physiotherapy and exercise into daily live.

Aim: To investigate the effect of a once-a-week physiotherapy combined with home exercises on joint health, FoH, muscle strength, pain, reaction time and dynamic balance.

Methods: 20 patients have hemophilic arthropathy in knee and/or ankle were randomly divided into 2 groups, named home exercise (HE) and comprehensive physiotherapy combined with home exercise (CPcwHE). In the clinical assessment, HJHS, manuel muscle tester, Fitlight® system for reaction time, functional reach test for dynamic balance were used and questioned the number of bleedings in the last 6 weeks for FoH. The CP group received comprehensive physiotherapy (manual therapy, neuromuscular electrical stimulation and exercises) 1 day a week, and did the exercises at home the other 2 days a week. The HE group performed the exercises given to CP at home 3 times a week. Evaluations were repeated at the end of 6 weeks.

Eligibility criteria: Inclusion Criteria: -Clinical diagnosis of hemophilia

-Clinical diagnosis of hemophilic arthropathy in ankle and/or

Exclusion Criteria:

* Clinical diagnosis of any neurological disease

Primary outcomes:
measure: Hemophilia Joint Health Score
timeFrame: 6 weeks
measure: Reaction time
timeFrame: 6 week
Secondary outcomes:
Other outcomes:
Locations:
city: Van
country: Turkey
facility: Van Yüzüncü Yıl University
Study officials:
affiliation: Van Yüzüncü Yıl University, Faculty of Health Science
name: Ayse Merve Tat, Asst. Prof.
role: STUDY_CHAIR
affiliation: Van Yüzüncü Yıl University, Faculty of Health Science
name: Necati Muhammed Tat
role: PRINCIPAL_INVESTIGATOR
affiliation: Van Yüzüncü Yıl University, Faculty of Health Science
name: Serbay Şekeröz, Asst. Prof.
role: PRINCIPAL_INVESTIGATOR
affiliation: Van Yüzüncü Yıl University, Faculty of Health Science
name: Meryem M Büke, Asst. Prof.
role: PRINCIPAL_INVESTIGATOR
affiliation: Van Yüzüncü Yıl University, Faculty of Medicine
name: Kamuran M Karaman, Prof.
role: STUDY_CHAIR
References: