Clinical trial NCT06811974: Comparison of the Efficiency of Tissue Adhesive (Periacryl 90) and Silk Suture in Mandibular Impacted Wisdom Surgery
Official title: Comparison of the Efficiency of Tissue Adhesive (Periacryl 90) and Silk Suture in Bilateral Mandibular Impacted Wisdom Dental Surgery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Impacted Mandibular Third Molar Extraction
Keywords: tissue adhesive
impacted wisdom tooth
silk suture
Lead sponsor: Yuzuncu Yıl University
Sponsor class: OTHER
First posted: 2025-02-06
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: In this study, bilateral It is aimed to compare the efficacy of tissue adhesive (Periacryl 90) and silk suture in mandibular impacted wisdom tooth surgery.

Detailed description: In the study carried out on a total of 30 patients, 21 females and 9 males, 60 fully impacted lower wisdom teeth were extracted bilaterally and in the same position. One of the bilateral bilateral teeth of the patients was randomly selected and tissue adhesive (Periacryl 90) was applied for wound closure as the experimental group, while the other tooth was determined as the control group and the wound was closed with silk suture. The selected party was determined by the closed envelope method. After the first impacted tooth was extracted, it was waited until the wound healed and the symptoms disappeared completely, then the other tooth was extracted. In both tooth extractions, wound healing, edema and trismus were evaluated on the 3rd and 7th days. Wound healing was evaluated as good, acceptable and bad. VAS (Visual Analog Scale) was used for pain assessment and assessment was made at 3, 6, 12 and 24 hours and 2, 3, 4, 5, 6 and 7 days.

Eligibility criteria: Inclusion Criteria:

* Healthy individuals aged 18-35 years who accepted the study conditions and had bilateral, bone or mucosal retention, and completely impacted wisdom teeth in the similar position with an indication for extraction due to prophylactic or orthodontic treatment in the lower jaw were included in the study.

Exclusion Criteria:

* Individuals with any systemic disease
* Individuals with a history of allergy to the drugs to be used in the study
* Pregnant and breastfeeding individuals
* Individuals with pain, swelling or trismus in the last 10 days
* Individuals with different positions on the right and left sides
* Individuals who did not sign the voluntary consent form
* Individuals with pathology in the impacted tooth area
* Individuals with limited mouth opening

Primary outcomes:
measure: Wound Healing
timeFrame: 3. and 7. days
measure: Edema
timeFrame: 3. and 7. days
measure: Trismus
timeFrame: 3. and 7. days
measure: VAS Pain Scor
timeFrame: 3, 6, 12 and 24 hours and 2, 3, 4, 5, 6 and 7 days.
Secondary outcomes:
Other outcomes:
Locations:
city: Van
country: Turkey
facility: Van Yüzüncü Yıl Üniversitesi Diş Hekimliği Fakültesi
Study officials:
References:
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