Clinical trial NCT00131326: A Study of the Safety and Efficacy of Synvisc and Depo-Medrol in Patients With Osteoarthritis of the Hip
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Osteoarthritis, Hip
Musculoskeletal Diseases
Keywords: osteoarthritis of the hip
Musculoskeletal Diseases
Lead sponsor: Sanofi
Sponsor class: INDUSTRY
First posted: 2005-08-18
Sex: ALL
Minimum age (years): 35
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This is a clinical study to investigate the safety and efficacy of Synvisc and Depo-Medrol in treating patients with osteoarthritis (OA) of the hip.


Eligibility criteria: Inclusion Criteria:

* Patients with symptomatic osteoarthritis pain of hip

Exclusion Criteria:

* Patients with current or prior conditions or treatment that would impede measurement of efficacy and safety

Primary outcomes:
measure: Pain relief
Secondary outcomes:
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: Alabama Clinical Therapeutics
state: Alabama
city: Huntsville
country: United States
facility: John Higginbotham, MD Sports Medicine
state: Alabama
city: Scottsdale
country: United States
facility: Affiliated Orthopedic Specialists
state: Arizona
city: Little Rock
country: United States
facility: Arkansas Orthopaedic Specialists
state: Arkansas
city: Los Angeles
country: United States
facility: Cedars-Sinai Orthopedic Center
state: California
city: Oakland
country: United States
facility: Jackson Arthritis Center
state: California
city: San Diego
country: United States
facility: Orthopedic Medical Group
state: California
city: Clearwater
country: United States
facility: Orthopedic Specialists of Tamp Bay, P.A.
state: Florida
city: Miami
country: United States
facility: Orthopedic Institute at Mercy Hospital
state: Florida
city: Columbus
country: United States
facility: Hughston Sports Medicine Foundation
state: Georgia
city: Meridian
country: United States
facility: Idaho Arthritis & Osteoporosis Center
state: Idaho
city: Chicago
country: United States
facility: Northwestern Orthopaedic Institute
state: Illinois
city: Morton Grove
country: United States
facility: Illinois Bone and Joint Institute, Ltd.
state: Illinois
city: Cedar Rapids
country: United States
facility: David S. Tearse, MD (Private Practice)
state: Iowa
city: Leawood
country: United States
facility: Kansas City Orthopedic Institute
state: Kansas
city: Lexington
country: United States
facility: Bluegrass Orthopaedics
state: Kentucky
city: Shreveport
country: United States
facility: Orthopedic Specialists of Louisiana
state: Louisiana
city: Baltimore
country: United States
facility: Maryland General Hospital
state: Maryland
city: Flint
country: United States
facility: Family Orthopedic Associates
state: Michigan
city: Saint Louis
country: United States
facility: Washington University School of Medicine
state: Missouri
city: New Brunswick
country: United States
facility: UMDNJ-RWJ University Orthopedic Group
state: New Jersey
city: New York
country: United States
facility: Hospital for Special Surgery
state: New York
city: Oklahoma City
country: United States
facility: Health Research Institute
state: Oklahoma
city: Grants Pass
country: United States
facility: Orthopedic Center for Joint Replacement & Sports Medicine
state: Oregon
city: Duncansville
country: United States
facility: Altoona Center for Clinical Research
state: Pennsylvania
city: Lancaster
country: United States
facility: Lancaster Orthopedic Group
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Allegheny Orthopedic Associates
state: Pennsylvania
city: Conway
country: United States
facility: Conway Medical Center
state: South Carolina
city: Chattanooga
country: United States
facility: Chattanooga Center for Sports
state: Tennessee
city: Lubbock
country: United States
facility: Gurdev Gill, MD (Private Practice)
state: Texas
city: Vinton
country: United States
facility: Carilion Bone and Joint Center, Vinton Orthopedic Surgery
state: Virginia
city: Seattle
country: United States
facility: Arthritis Northwest
state: Washington
Study officials:
affiliation: Genzyme, a Sanofi Company
name: Medical Monitor
role: STUDY_DIRECTOR
References:
citation: Spitzer AI, Bockow BI, Brander VA, Yates JW, MacCarter DK, Gudger GK, Haller S, Lake SL, Magilavy DB. Hylan G-F 20 improves hip osteoarthritis: a prospective, randomized study. Phys Sportsmed. 2010 Jun;38(2):35-47. doi: 10.3810/psm.2010.06.1781.