Clinical trial NCT06507501: Effects of Exercise Training with Blood Flow Restriction
Official title: Effects of Exercise Training with Blood Flow Restriction on Lower Extremity Muscle Strength, Balance, Functional and Cognitive Performance in Healthy Individuals
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: Blood Flow Restriction Exercise Training
Muscle Strength
Balance
Functional Performance
Cognitive Performance
Lead sponsor: Atlas University
Sponsor class: OTHER
First posted: 2024-07-18
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: In this study, it was aimed to compare the effects of low load blood flow restriction exercise (LL-BFRE) training versus high load resistance exercise (HL-RE) training in healthy young individuals on the parameters of lower extremity muscle strength, dynamic and static postural balance, functional performance and cognitive performance.

Detailed description: In this randomized controlled study, there will be two study group. Study group 1 will recieve low load blood flow restriction exercise training and Study group 2 will recieve high load resistance exercise training for 6 weeks, 2 exercise sessions weekly.

At baseline assessment, individuals who met the inclusion criteria, informed by the researcher and accept the participate in the study, researcher will record the participants' sociodemographic and physical informations and then, asess the lower extremity muscle strength with Hand-held digital dynamometer, dynamic postural balance with Y-Balance Test-Lower Quarter, static postural balance with Single Leg Stance Test (Eyes open/closed condition), functional performance with 6-Minute Walking Test and cognitive performance with Stroop Word and Colour Test and Trail Making Test.

At the end of the 6 week exercise training all participants will undergo the same assessments.

Eligibility criteria: Inclusion Criteria:

* Volunteering to participate in the study,
* Being between the ages of 18-30.

Exclusion Criteria:

* Presence of any painful condition or pathology involving the lower extremity and lumbar spine and the presence of a surgical history,
* Presence of serious malalignment and deformity affecting the lower extremity,
* Presence of neuromuscular and metabolic disease,
* Presence of any disease affecting lower extremity circulation,
* Having a history of deep vein thrombosis and the presence of peripheral vascular disease,
* Presence of endothelial dysfunction (ED) and any disease that may cause ED,
* Presence of active infection, cancer and having received radiotherapy / chemotherapy,
* Continuous use of anticoagulant medication,
* Having had COVID-19 in the last 3 months or having long COVID syndrome,
* Presence of a cognitive or mental disorder that would disability to participate in the study,
* Disruption of exercise program 3 times in a row

Primary outcomes:
measure: Muscle Strength
timeFrame: Baseline to 6 weeks after exercise training
measure: Dynamic Balance
timeFrame: Baseline to 6 weeks after exercise training
measure: Static Balance
timeFrame: Baseline to 6 weeks after exercise training
Secondary outcomes:
measure: Funtional Performance
timeFrame: Baseline to 6 weeks after exercise training
measure: Funtional Performance
timeFrame: Baseline to 6 weeks after exercise training
measure: Cognitive Performance
timeFrame: Baseline to 6 weeks after exercise training
measure: Cognitive Performance
timeFrame: Baseline to 6 weeks after exercise training
Other outcomes:
measure: Sociodemographic Information
timeFrame: Baseline
measure: Physical Assessment
timeFrame: Baseline
Locations:
city: Istanbul
country: Turkey
facility: Onur Turan
state: Kağıthane
Study officials:
affiliation: Atlas University
name: Onur Turan, Bachelor's
role: PRINCIPAL_INVESTIGATOR
References: