Clinical trial NCT05177757: Feasibility of a Yoga Program for Veterans With PTSD
Official title: Feasibility of a Yoga Program for Veterans With PTSD
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stress Disorders, Post-Traumatic
Lead sponsor: Marquette University
Sponsor class: OTHER
First posted: 2022-01-05
Enrollment: 14
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This study is designed to examine the feasibility of a 12-week yoga program on physiological and psychological health and its neurobiological mechanisms in N=15 veterans with posttraumatic stress disorder (PTSD). The investigators will be examining specific parameters of health and mechanisms before and after the yoga program.


Eligibility criteria: Inclusion Criteria:

* U.S. Military Veteran
* 18 years of age or older
* Diagnosis of PTSD as assessed by a score of \>30 on the PTSD-Checklist Version 5 (PCL-5)
* Willing and able to attend testing and yoga sessions at the Athletic and Human Research Performance Center (AHPRC) on the campus of Marquette University
* Clear to participate in physical activity based on the Physical Activity Readiness Questionnaire (PARQ+)

Exclusion Criteria:

* Currently pregnant or trying to become pregnant
* Positive score to one or more items on the PAR-Q+ without physician approval
* Already established regular use of yoga (i.e., more than one day per week)

Primary outcomes:
measure: Endocannabinoid assay
timeFrame: Change in ligands from baseline to12 weeks
measure: Cortisol assay
timeFrame: Change in cortisol from baseline to12 weeks
measure: Cognitive functioning using a computerized battery
timeFrame: Change in performance from baseline to12 weeks
measure: Body Mass Index (BMI)
timeFrame: Change in BMI from baseline to12 weeks
measure: Blood pressure
timeFrame: Change in blood pressure from baseline to12 weeks
measure: Heart rate
timeFrame: Change in heart rate from baseline to12 weeks
measure: Heart rate variability (HRV)
timeFrame: Change in HRV from baseline to12 weeks
measure: Lung functioning
timeFrame: Change in lung functioning from baseline to12 weeks
measure: Range of motion
timeFrame: Change in range of motion from baseline to12 weeks
measure: Body composition
timeFrame: Change in body composition from baseline to12 weeks
measure: Hand grip strength
timeFrame: Change in hand grip strength from baseline to12 weeks
measure: Aerobic fitness
timeFrame: Change in aerobic fitness from baseline to12 weeks
measure: Physical activity
timeFrame: Change in physical activity from baseline to12 weeks
measure: Severity of posttraumatic stress disorder (PTSD)
timeFrame: Change in scores from baseline to12 weeks
measure: Frequency of physical activity
timeFrame: Change in scores from baseline to12 weeks
measure: Physical health rating
timeFrame: Change in scores from baseline to12 weeks
measure: Severity of sleep disturbance
timeFrame: Change in scores from baseline to12 weeks
measure: Mindfulness rating
timeFrame: Change in scores from baseline to12 weeks
measure: Frequency of yoga rating
timeFrame: Change in scores from baseline to12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Milwaukee
country: United States
facility: Marquette University
state: Wisconsin
Study officials:
affiliation: Marquette University
name: Jacklynn Fitzgerald, PhD
role: PRINCIPAL_INVESTIGATOR
References: