Clinical trial NCT03357601: High Intensity Interval Training vs Moderate Continuous Endurance Exercise Training on Program Adherence
Official title: The Effect of High Intensity Interval vs Moderate Continuous Endurance Exercise Training on Program Adherence
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Physical Activity
Fat Burn
Keywords: High Intensity Interval
Moderate Endurance Exercise
Fat Loss
Endurance Capacity
Lead sponsor: Western University, Canada
Sponsor class: OTHER
First posted: 2017-11-30
Enrollment: 40
Sex: ALL
Minimum age (years): 19
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Each participant will be match-paired to either HIIT or MCEET group based on their time to complete a mile run. There will be rank from 1 to 40, where number one will be assigned randomly to one group while two goes to the other group. Then, number three goes to the second group and fourth is assigned to the first group. Alternating patterns will be continued thereafter.
Primary purpose: TREATMENT

Brief summary: This study examines whether high intensity interval training (HIIT) or moderate, continuous endurance exercise training (MCEET) results in greater program adherence when matched for session time. Body composition and endurance capacity will also be measured to identify any significant changes among two exercise groups. It is hypothesized that HIIT will result in greater program adherence as well as greater improvements in body composition and endurance capacity. Both exercise groups will complete 20 minutes sessions (which include exercise) three times per week for five week. The first week will be supervised by study investigators while the remainder of the study will be unsupervised in order to examine how free-living individuals adhere to two exercise programs. There will be no attempt to restrict food intake during the exercise intervention. Body composition will be measured by densitometry \[body mass/body volume\] using a BodPod. Endurance capacity will be assessed using a mile run. Two validated questionnaires \[Physical activity enjoyment scale and Exercise adherence ratings scale\] as well as heart rate data (recorded before, during and after each training sessions) will be used to confirm exercise adherence. These data may help us determine the optimal type of exercise program to maintain healthy body composition.

Detailed description: Upon completing informed consent, all the eligible participants will have their body composition measured at the Exercise Nutrition Research Laboratory, Western University, using non-invasive air displacement plethysmography (BodPod). This requires participants to sit in a chamber while space \[volume\] their bodies take up is assessed. This along with their body mass allows body density \[d=m/v\] and body composition to be determined pre and post the 5-week exercise intervention. Upon completing the body composition measurements, participants will have their endurance capacity assessed by performing a timed one-mile run (which will be used as an index of their endurance capacity). Participants will be advised to dress appropriately for physical activity including proper footwear.

Each participant will be matched to either HIIT or MCEET group based on their one-mile run time. The HIIT group will perform six, 20-second bouts of high-intensity interval exercise separated by 2 minutes of active recovery (walking) while the MCEET group will perform 14 minutes of continuous endurance exercise at 70% of Maximum Heart Rate (MHR). Both exercise protocols will include 3 minutes of warm up and cool down at a 30% MHR, for a total of 20 minutes for each treatment. The first week of the exercise intervention will consist of one-on-one supervised treadmill training, three times per week in the lab. From week two to five, participants will follow the same exercise program on their own at their preferred gym three times per week in order to examine free-living individuals adhere to two exercise programs.

All participants will log their heart rate before, during, and immediately after each training session using a free heart rate monitor mobile App to ensure safety and achievement of their targeted heart rate. Further, they will complete two validated questionnaires \[physical activity enjoyment scale and exercise adherence rating scale\] as well ratings of perceived exertion scale after the 6th, 9th and 15th session. Finally, no attempt will be made to modify the participants daily diet, but a 3-day food log will be collected to assess food intake.

Eligibility criteria: Inclusion Criteria:

* Healthy
* 19-35 years old
* Engage in physical activity less than three times per week
* Must have access to the gym
* Must have smartphones (such as Android, Cat phone, Google Nexus, Samsung Galaxy, iPhone, Microsoft Lumia, myTouch or Phablets)
* Must have access to Apps (such as MyFitnessPal, Rise Up, Calorific, My Diet Coach, Yazio, On The Regimen, See How You Eat, Lost It, MyNetDiary or MyPlate)
* Must be able to run a mile

Exclusion Criteria:

* Diabetic
* Pregnant
* History of fainting
* Low and high blood pressure
* Heart disease
* Migraines
* Experience with heartburn
* Smokers
* Respiratory diseases
* Engage in physical activity more than two times per week
* Answering YES to any questions from page 1 of GAQ

Primary outcomes:
measure: Program Adherence
timeFrame: 5 weeks
measure: Program Adherence
timeFrame: 5 weeks
Secondary outcomes:
measure: Body Composition
timeFrame: 5 weeks
measure: Endurance Capacity
timeFrame: 5 weeks
Other outcomes:
Locations:
city: London
country: Canada
facility: 3M Centre, Room 2225
state: Ontario
Study officials:
affiliation: Western University, Canada
name: Peter Lemon, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Gillen JB, Martin BJ, MacInnis MJ, Skelly LE, Tarnopolsky MA, Gibala MJ. Twelve Weeks of Sprint Interval Training Improves Indices of Cardiometabolic Health Similar to Traditional Endurance Training despite a Five-Fold Lower Exercise Volume and Time Commitment. PLoS One. 2016 Apr 26;11(4):e0154075. doi: 10.1371/journal.pone.0154075. eCollection 2016.
citation: Macpherson RE, Hazell TJ, Olver TD, Paterson DH, Lemon PW. Run sprint interval training improves aerobic performance but not maximal cardiac output. Med Sci Sports Exerc. 2011 Jan;43(1):115-22. doi: 10.1249/MSS.0b013e3181e5eacd.
citation: Thum JS, Parsons G, Whittle T, Astorino TA. High-Intensity Interval Training Elicits Higher Enjoyment than Moderate Intensity Continuous Exercise. PLoS One. 2017 Jan 11;12(1):e0166299. doi: 10.1371/journal.pone.0166299. eCollection 2017.