Clinical trial NCT00686491: Respiratory Health of Elite Athletes
Official title: Center of Excellence in CardioRespiratory Health of High-level Athletes: Evaluation of Long-term Effects of Training.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Asthma
Cardiovascular Diseases
Metabolic Diseases
Keywords: Asthma
Environment
Type of sport
Cardiovascular disease
Athletes
Lead sponsor: Laval University
Sponsor class: OTHER
First posted: 2008-05-29
Enrollment: 133
Sex: ALL
Minimum age (years): 14
Maximum age (years): 45
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Athletes training in the province of Quebec. Controls from Quebec schools and universities.

Brief summary: Eleven National Sports Teams are located in the Quebec Metropolitan Area. In these groups, many athletes are aiming for Olympic medals in Beijing 2008 and Vancouver 2010 Olympic Games. A consultation of the coaches of these National Teams revealed that although a large proportion of these athletes present various cardio-respiratory symptoms, they do not have a rapid access to a systematic medical evaluation and follow-up. Furthermore, little is done in regard to prevention and optimization of treatment of pulmonary and cardiac conditions in the elite athlete's population of the Quebec area.

Cardiorespiratory problems are therefore commonly found in high-level athletes. However, these pathologies are not well characterized in athletes and the associated symptoms often not well perceived. These problems can be serious and it is important to detect them before they appear1 while setting up a systematic medical follow-up. Health professionals should monitor health of the young athletes and help to reduce the risks associated with high level exercise. The following project is an evaluation and follow-up program of high-level athletes, aiming at gathering key-information on long-term effects of high-level training on cardio-respiratory and metabolic parameters. Our aims will be

1. to establish a long-term program of systematic evaluation and follow-up of cardiorespiratory health and performance of high elite athletes.
2. to evaluate the prevalence of respiratory, circulatory and metabolic problems among high-level athletes
3. to evaluate the effects of treatments on cardiorespiratory conditions and exercise performance in athletes who need asthma medication.


Eligibility criteria: Inclusion Criteria:

* Athletes training more than 10 hours per week-

Exclusion Criteria:

* asthma or other pathologies that may interfere with the study
* Smokers
* Obese of with a BMI more than 29

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Quebec
country: Canada
facility: Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Study officials:
affiliation: Hôpital LAval
name: Paul POIRIER, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bougault V, Blouin E, Turmel J, Boulet LP. Airway response to methacholine following eucapnic voluntary hyperpnea in athletes. PLoS One. 2015 Mar 19;10(3):e0121781. doi: 10.1371/journal.pone.0121781. eCollection 2015.
citation: Turmel J, Bougault V, Boulet LP, Poirier P. Exaggerated blood pressure response to exercise in athletes: dysmetabolism or altered autonomic nervous system modulation? Blood Press Monit. 2012 Oct;17(5):184-92. doi: 10.1097/MBP.0b013e3283573509.
citation: Bougault V, Turmel J, Boulet LP. Bronchial challenges and respiratory symptoms in elite swimmers and winter sport athletes: Airway hyperresponsiveness in asthma: its measurement and clinical significance. Chest. 2010 Aug;138(2 Suppl):31S-37S. doi: 10.1378/chest.09-1689. Epub 2010 Apr 2.