Clinical trial NCT04938791: Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults
Official title: Relationship Between Perceive Effort, Physiological and Kinematic Changes During Upper Limbs Isometric Activity and Its Relationship With the Socio-demographic Characteristics
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Fatigue
Keywords: Respiration
Perceived
Kinematics
Performance
Lead sponsor: Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa
Sponsor class: OTHER
First posted: 2021-06-24
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: BASIC_SCIENCE

Brief summary: The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic characteristics, level of activity and quality of life.


Eligibility criteria: Inclusion Criteria:

* Healthy
* Minimum age of 18 years;

Exclusion Criteria:

* Unable to provide written consent
* History of heart, cardiovascular and / or respiratory disease,
* Known untreated hypertension, cardiomyopathy, or exercise intolerance
* Presence of cognitive or neurological disorders
* Neuromuscular or orthopaedic disorder that limits the movement of the upper limb to 90° flexion or the maintenance of that position
* BMI ≥ 40

Primary outcomes:
measure: Change from Baseline in perceived effort on the Borg category-ratio 10-point scale (CR 10)
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in heart rate
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in respiratory rate
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in heart rate variability (HRV)
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in electrodermal activity (EDA)
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in muscle action potential amplitude through surface electromyography (sEMG)
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in muscle action potential duration through surface electromyography (sEMG)
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in muscle action potential frequency through surface electromyography (sEMG)
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in respiratory pattern through inertial motion units (IMU) from baseline and during activity
timeFrame: From baseline to end of activity, up to 15 minutes
measure: Change from Baseline in upper limb motion angular acceleration through inertial motion units (IMU) system
timeFrame: From baseline to end of activity, up to 15 minutes
Secondary outcomes:
measure: Health Status
timeFrame: Before isometric activity
measure: Physical activity level
timeFrame: Before isometric activity
Other outcomes:
Locations:
city: Lisboa
country: Portugal
facility: Escola Superior de Saúde da Cruz Vermelha Portuguesa - Lisboa
Study officials:
affiliation: Universidade da Coruña
name: Daniel López López, PhD
role: STUDY_DIRECTOR
References: