Clinical trial NCT06804304: Efficacy of Music-Based Telerehabilitation After Stroke
Official title: Efficacy of Music-Based Telerehabilitation After Stroke
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Stroke
Keywords: stroke
music
telerehabilitation
attention
executive function
memory
cognition
language
aphasia
motor
hemiparesis
emotion
depression
anxiety
quality of life
magnetic resonance imaging
neuroplasticity
Lead sponsor: University of Helsinki
Sponsor class: OTHER
Collaborators: name: HUS Neurocenter
name: HUS Medical Imaging Centre
name: University of Jyvaskyla
name: Finnish Brain Association
name: Uusimaa Stroke Association
First posted: 2025-02-03
Enrollment: 100
Sex: ALL
Minimum age (years): 30
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke. The main questions it aims to answer are: 1) Can the music intervention improve recovery of cognitive, verbal, motor, and emotional deficits after stroke, 2) can the music intervention enhance structural and functional recovery of the brain, and (3) how different demographic, musical, and clinical background factors affect the way the music intervention works. Researchers will compare the music intervention to standard (usual) care to see if the music intervention works to treat the deficits caused by stroke. Subjects are stroke patients who will participate either in the music intervention 5 times/week for 10 weeks in addition to standard care or receive standard care only. During the trial, the subjects will undergo neuropsychological testing and magnetic resonance imaging (MRI) three times: at baseline (before the intervention), at 3-month stage (immediately after the intervention), and at 6-month stage (3 months after the intervention).


Eligibility criteria: Inclusion Criteria:

* Left or right hemisphere stroke which has occurred 3-12 months ago
* At least mild cognitive deficit and mild aphasia / upper-extremity hemiparesis caused by the stroke
* Age 30-80 years
* Right-handed
* Finnish-speaking (or bilingual, able to participate in Finnish)
* Understands the purpose of the study and is able to give informed consent

Exclusion Criteria:

* Prior significant hearing or visual impairment
* Prior severe psychiatric illness (e.g., schizopheria, bipolar disorder, severe unipolar depression)
* Prior severe neurological illness (e.g., brain injury, dementia; can have prior TIA or mild stroke)

Primary outcomes:
measure: Change in the cognitive functioning summary score from baseline to 3-month stage
timeFrame: Baseline and 3-month stage
measure: Change in the speech production summary score from baseline to 3-month stage
timeFrame: Baseline and 3-month stage
measure: Change in the upper-extremity motor function summary score from baseline to 3-month stage
timeFrame: Baseline and 3-month stage
measure: Change in the mood and quality of life summary score from baseline to 3-month stage
timeFrame: Baseline and 3-month stage
Secondary outcomes:
measure: Change in the cognitive functioning summary score from baseline to 6-month stage
timeFrame: Baseline and 6-month stage
measure: Change in the speech production summary score from baseline to 6-month stage
timeFrame: Baseline and 6-month stage
measure: Change in the upper-extremity motor function summary score from baseline to 6-month stage
timeFrame: Baseline and 6-month stage
measure: Change in the mood and quality of life summary score from baseline to 6-month stage
timeFrame: Baseline and 6-month stage
measure: Change in the attention summary score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the executive function summary score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the working memory summary score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the MoCA total score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the MoCA Verbal Fluency subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the SART correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the SART reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Reaction Time subtest reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Trail Making subtest (A part) correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Trail Making subtest (A part) reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Trail Making subtest (B part) correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Trail Making subtest (B part) reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Trail Making subtest (difference between B part and A part) correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the FAT Trail Making subtest (difference between B part and A part) reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the Simon Task (Congruence part) correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the Simon Task (Congruence part) reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the Simon Task (Incongruence part) correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the Simon Task (Incongruence part) reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the Simon Task (difference between Incongruence part and Congruence part) correct responses from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the Simon Task (difference between Incongruence part and Congruence part) reaction times from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Digit Span subtest (forward recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Digit Span subtest (backward recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Digit Span subtest (total score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Spatial Span subtest (forward recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Spatial Span subtest (backward recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Spatial Span subtest (total score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Word Lists subtest (1st learning trial score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Word Lists subtest (learning trials change score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Word Lists subtest (learning trials total score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Word Lists subtest (learning trials recognition score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Word Lists subtest (delayed recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WMS-III Word Lists subtest (delayed recognition score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the RBMT Story Recall subtest (immediate recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the RBMT Story Recall subtest (immediate recognition score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the RBMT Story Recall subtest (delayed recall score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the RBMT Story Recall subtest (delayed recognition score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BIT Star Cancellation subtest (left side score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BIT Star Cancellation subtest (right side score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BIT Star Cancellation subtest (laterality index) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BIT Star Cancellation subtest (total score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Conversational Question subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Conversational Question & Picture Description subtests (information content score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Conversational Question & Picture Description subtests (fluency of speech score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Spontaneous speech score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Conversational Question & Picture Description subtests (efficiency score) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Repetition subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Object Naming subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Word Fluency subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Sentence Completion subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Responsive Speech subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Naming and Word Finding score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the WAB Sequential Commands subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BDAE Verbal Agility subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BDAE Automatized Sequences subtest score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Grasp subscale score (paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Grasp subscale score (non-paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Grip subscale score (paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Grip subscale score (non-paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Pinch subscale score (paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Pinch subscale score (non-paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Gross Movement subscale score (paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT Gross Movement subscale score (non-paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT total score (paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT total score (non-paretic hand) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the ARAT total score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BBT paretic hand score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BBT non-paretic hand score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the BBT total score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the PPT paretic hand score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the PPT non-paretic hand score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the PPT both hands score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the PPT total score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in the PPT Assembly score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in PROMIS Depression subscale total score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in PROMIS Anxiety subscale total score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Strength subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Hand Function subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS ADL subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Mobility subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Communication subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Emotion subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Memory and Thinking subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Participation subscale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Recovery item score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS total score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Strength subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Hand Function subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS ADL subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Mobility subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Communication subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Emotion subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Memory and Thinking subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Participation subscale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS Recovery item score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in SIS total score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in MAL total score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in MAL total score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CAL Quantity of Communication scale score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CAL Quality of Communication score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CAL total score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CAL Quantity of Communication scale score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CAL Quality of Communication score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CAL total score (proxy report of family member) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in CFQ total score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in PRMQ total score (patient self-report) from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
Other outcomes:
measure: Change in the MIT phrase repetition score from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in verbal production in a singing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in musical production in a singing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in melodic production using paretic hand in a playing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in melodic production using non-paretic hand in a playing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in rhythmic production using paretic hand in a playing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in rhythmic production using non-paretic hand in a playing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in movement quality of paretic hand in a playing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in movement quality of non-paretic hand in a playing task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance accuracy using paretic hand in a gross motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance accuracy using non-paretic hand in a gross motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance timing using paretic hand in a gross motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance timing using non-paretic hand in a gross motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in movement quality of paretic hand in a gross motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in movement quality of non-paretic hand in a gross motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance accuracy using paretic hand in a fine motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance accuracy using non-paretic hand in a fine motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance timing using paretic hand in a fine motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in performance timing using non-paretic hand in a fine motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in movement quality of paretic hand in a fine motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in movement quality of non-paretic hand in a fine motor rhythmic task of the music intervention from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in sMRI regional grey matter volume from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in dMRI structural connectivity from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in fMRI resting-state functional connectivity from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in fMRI functional connectivity during music listening from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
measure: Change in fMRI regional brain activation during music listening from baseline to 3-month and 6-month stages
timeFrame: Baseline, 3-month stage, and 6-month stage
Locations:
city: Helsinki
country: Finland
facility: University of Helsinki / Faculty of Medicine / Department of Psychology
Study officials:
affiliation: University of Helsinki / Faculty of Medicine / Department of Psychology
name: Teppo Särkämö, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: