louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02034448: CRRTNet Registry- A Prospective Observational Registry
Official title: CRRTNet Outcome Registry
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Continuous Renal Replacement Therapy
Keywords: CRRT
Renal
Kidney
adults
registry
AKI
Lead sponsor: AKI Critical Care Research Foundation
Sponsor class: OTHER
First posted: 2014-01-13
Enrollment: 2000
Sex: ALL
Minimum age (years): 18
Maximum age (years): 89
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: This is a prospective observational registry. A minimum sample size of 2000 patients with the detailed information being obtained would embody the largest and most detailed repository of adult CRRT patient information available.

Brief summary: An observational registry to monitor the outcome of CRRT in adults with acute kidney injury.

Detailed description: Continuous Renal Replacement Therapy (CRRT) is a form of dialysis provided to critically ill patients with acute renal failure, now known as acute kidney injury (AKI). While we have extensive experience with this therapy in critically ill patients, there is no consensus on when to start CRRT or a clinical standard as to the best possible way to deliver the therapy. Previous studies have examined one aspect of CRRT in detail (for instance the dose of delivered therapy, or anticoagulation strategies) or have been small single center studies, or large multinational studies examining very basic practice patterns. This is a prospective observational cohort study. All patients who receive CRRT as part of their standard of local care will be eligible for the study.

Eligibility criteria: Inclusion Criteria: Patients initiating CRRT c. Age \> 18 years of age and \<89 year of age -

Exclusion Criteria: ˂ 18 years of age and \> 89 year of age

-

Primary outcomes:
measure: Mortality
timeFrame: 30 days
Secondary outcomes:
measure: Length of Stay
timeFrame: 6 months
Other outcomes:
Locations:
city: Ann Arbor
country: United States
facility: Mike Heung
state: Michigan
Study officials:
affiliation: University of Michigan Hospital
name: Mike Heung, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Heung M, Bagshaw SM, House AA, Juncos LA, Piazza R, Goldstein SL. CRRTnet: a prospective, multi-national, observational study of continuous renal replacement therapy practices. BMC Nephrol. 2017 Jul 6;18(1):222. doi: 10.1186/s12882-017-0650-2.
Clinical trial NCT01501448: Oral Estradiol Valerate Versus Oral Contraceptive Pill in Invitro Fertilization Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Infertility
Lead sponsor: IVI Madrid
Sponsor class: OTHER
First posted: 2011-12-29
Enrollment: 118
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 38
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The recent controversy regarding the use of pill for cycle planning in GnRH antagonists IVF cycle has driven the search for new ways to plan IVF cycles in order to avoid weekends or to equally distribute the workload. Recently, mid-late luteal phase oral estrogens seem to be as good as the pill. The investigators will compare OCP vs oral estrogens to plan the initiation of IVF cycles.


Eligibility criteria: Inclusion Criteria:

* 1st or 2nd IVF cycle
* BMI \<30 kg/m2
* regular menstrual cycles
* basal FSH \<10IU and E2 \<60pg/mL

Exclusion Criteria:

* polycystic ovaries
* endometriosis
* previous ovarian surgery
* previous low ovarian response

Primary outcomes:
measure: Implantation rate
timeFrame: 20 days after the embryo transfer
Secondary outcomes:
Other outcomes:
Locations:
city: Madrid
country: Spain
facility: IVI Madrid
Study officials:
References:
citation: Hauzman EE, Zapata A, Bermejo A, Iglesias C, Pellicer A, Garcia-Velasco JA. Cycle scheduling for in vitro fertilization with oral contraceptive pills versus oral estradiol valerate: a randomized, controlled trial. Reprod Biol Endocrinol. 2013 Sep 28;11:96. doi: 10.1186/1477-7827-11-96.
Clinical trial NCT00241657: Immune Responses to BCG Vaccination in Malawi and the UK
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE2
Conditions: Immunity, Cellular
Hypersensitivity, Delayed Type
Lead sponsor: London School of Hygiene and Tropical Medicine
Sponsor class: OTHER
First posted: 2005-10-19
Sex: ALL
Minimum age (years): 12
Maximum age (years): 25
Standard ages: CHILD
ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: BCG vaccination has been found to provide greater protection against TB in the UK than in Malawi. This study compares immune responses in BCG-vaccinated and unvaccinated teenagers and young adults in Malawi and in the UK.


Eligibility criteria: Inclusion Criteria:

* BCG unvaccinated
* HIV negative
* Not pregnant
* Informed Consent

Exclusion Criteria:

* HIV positive
* Pregnant
* Seriously ill

Primary outcomes:
measure: Delayed-type hypersensitivity
measure: cytokine responses (eg IFNg) to mycobacterial antigens
Secondary outcomes:
measure: scar size
Other outcomes:
Locations:
city: Chilumba
country: Malawi
facility: Karonga Prevention Study
state: Karonga District
city: Ilford
country: United Kingdom
facility: Redbridge and Waltham Forest Primary Care Trust
state: Essex
Study officials:
affiliation: London School of Hygiene and Tropical Medicine
name: Paul EM Fine, VMD, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00343057: DISCO - Influence of a Simple Information Booklet on the Evolution of Acute Low Back Pain (LBP)
Official title: Influence of a Simple Information Booklet on the Evolution of Acute Low Back Pain (LBP): a Quasi-experimental Study in a Primary Care Setting.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Acute Low Back Pain
Lead sponsor: Sanofi
Sponsor class: INDUSTRY
First posted: 2006-06-22
Enrollment: 2830
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Sampling method: PROBABILITY_SAMPLE
Study population: Subjects presenting with acute common low back pain.

Brief summary: To assess the impact of standardized written information on outcome in acute LBP.

Detailed description: A 3-month prospective, controlled study with a quasi-experimental design (i.e., a nonrandomized controlled sample with geographic stratification \[30 areas\]). Control and intervention areas ARE selected for their similarities in rural-to-urban distribution of the population and patients' access to GPs and to minimize risk of overlap between areas.

Eligibility criteria: Inclusion Criteria:

* Each GP have to enroll up to 4 patients with acute LBP.

Exclusion Criteria:

Patients are excluded if they

1. are less than 18 years old;
2. have pain for more than 4 weeks;
3. have pain intensity for the previous 24 hours less than 3 on a 11-point numeric scale (0= no pain, 10=maximal pain);
4. have sciatica;
5. have had a previous episode of acute LBP during the last 12 months;
6. have no occupational activities;
7. have consulted another practitioner for the same episode of back pain;
8. are pregnant;
9. have back pain related to infection, tumor, or inflammatory disease; or (j) have previously undergone back surgery.

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Paris
country: France
facility: Sanofi-Aventis
Study officials:
affiliation: Sanofi
name: COUDERC, Dr
role: STUDY_DIRECTOR
References:
citation: Coudeyre E, Tubach F, Rannou F, Baron G, Coriat F, Brin S, Revel M, Poiraudeau S. Effect of a simple information booklet on pain persistence after an acute episode of low back pain: a non-randomized trial in a primary care setting. PLoS One. 2007 Aug 8;2(8):e706. doi: 10.1371/journal.pone.0000706.
Clinical trial NCT05333757: Assessing the Quality of Life in Adults With Spinal Deformity
Official title: Assessing the Quality of Life in Adults With Spinal Deformity: a Retrospective Comparison Between Two Questionnaires
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Scoliosis
Quality of Life
Lead sponsor: Istituto Scientifico Italiano Colonna Vertebrale
Sponsor class: OTHER
First posted: 2022-04-19
Enrollment: 150
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Adult patients treated conservatively for idiopathic scoliosis or undergoing clinical monitoring

Brief summary: Spinal deformities, such as scoliosis, can have a significant impact on the physical and psychological health of patients. Over time, specific tools for this condition have been developed to investigate the extent of this impact, such as the SRS-22 questionnaire and ISYQOL questionnaire.

The latter was initially used for underage patients, but given that some of them continue their therapy and the monitoring beyond the age of 18, we have continued its use in these subjects as well. Given the clinical usefulness and given the lack of questionnaires developed in the Rasch environment for adults, we have extended the application of the ISYQOL questionnaire to the adult population. However, a comparison between the ISYQOL and SRS-22 in adults has not yet been made.

The objective of this study is to verify the validity of ISYQOL and to compare the properties of ISYQOL with those of the SRS-22 questionnaire in adults with spinal deformity.


Eligibility criteria: Inclusion Criteria:

* Age ≥ 18 years
* Diagnosis of idiopathic or degenerative scoliosis with ≥30 ° Cobb curve

Exclusion Criteria:

* Previous spinal surgery
* Previous and relevant illnesses, surgery or trauma

Primary outcomes:
measure: Statistical properties of SRS-22 and ISYQOL questionnaire
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Milan
country: Italy
facility: ISICO
state: Mi
Study officials:
References:
Clinical trial NCT05762757: Patient-centered Educational Material to Improve Colposcopy Adherence
Official title: Patient-centered Educational Material to Improve Colposcopy Adherence
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cervical Cancer Screening
Keywords: cervical cancer screening
colposcopy
patient education
Lead sponsor: Washington University School of Medicine
Sponsor class: OTHER
Collaborators: name: American Association of Obstetricians and Gynecologists
First posted: 2023-03-10
Enrollment: 25
Sex: FEMALE
Minimum age (years): 21
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: The long-term goal is to develop, test, and disseminate a social needs navigator intervention that improves colposcopy adherence. Based on stakeholder feedback, this study addresses the need to include patient-centered educational material to the navigator program in order to improve patients' health literacy regarding cervical cancer prevention.

Detailed description: The investigators will evaluate the effectiveness of the colposcopy educational material. The investigators aim to recruit 25 newly referred colposcopy patients before their appointment, ask them to take a 5-minute test about their knowledge of colposcopy, have them view an online demo of the educational resources, and then retake the test.

Eligibility criteria: Inclusion Criteria:

* Age 21 years or older
* Abnormal cervical screen confirmed by cytology or pathology
* Referred to Washington University School of Medicine (WUSM) colposcopy clinic

Exclusion Criteria:

* History of cervical cancer
* Unable to consent

Primary outcomes:
measure: Change in participant knowledge of colposcopy
timeFrame: Prior to viewing educational material and after viewing educational material (Day 1)
Secondary outcomes:
measure: Acceptability of educational material as measured by the Acceptability of Intervention Measure
timeFrame: Day 1
measure: Appropriateness of educational material as measured by the Intervention Appropriateness Measure
timeFrame: Day 1
measure: Feasibility of educational material as measured by the Feasibility of Intervention Measure
timeFrame: Day 1
measure: Number of participants who stated that the educational material will influence their intention to adhere to colposcopy
timeFrame: Day 1
Other outcomes:
Locations:
city: Saint Louis
country: United States
facility: Washington University School of Medicine
state: Missouri
Study officials:
affiliation: Washington University School of Medicine
name: Lindsay M Kuroki, M.D.
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT05773157: Evaluation of SNAP-Ed Online Modules to Improve Responsive Feeding Practices of Caregivers
Official title: Evaluation of SNAP-Ed Online Modules to Improve Responsive Feeding Practices of Caregivers
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Feeding Behavior
Lead sponsor: Penn State University
Sponsor class: OTHER
First posted: 2023-03-17
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: A single pilot group of participants will complete the online modules and evaluate their effectiveness using pre and post surveys.
Primary purpose: PREVENTION

Brief summary: Evaluation of three online modules developed by the Center for Childhood Obesity Research for caregivers of children ages 5-12 years old participating in SNAP-Ed programing.

Detailed description: the Center for Childhood Obesity Research developed three online modules for caregivers of children ages 5-12 years old who are participating in SNAP-Ed programming. These modules were developed to be used within the context of normal programming that participants will receive in any given year. The specific aim are as follows:

Aim #1: To examine acceptability of these modules by caregivers participating in SNAP-Ed programming. This will be assessed by evaluating acceptability questions answered by participants after completing the modules.

Aim #2: To examine the feasibility of these modules by caregivers participating in SNAP-Ed programming, assessed by \>60% completion rate of all three modules.

Online module content will focus on topics such as:

* Shared Responsibility of Feeding:
* Parent Provides, Child Decides
* Family Mealtimes
* Hunger and Fullness
* Avoiding use of controlling feeding practices

Eligibility criteria: Inclusion Criteria:

* Primary caregiver of a child between the ages of 2 to 16 years
* Over the age of 18
* English-speaking
* Have a reliable internet source and active email account so they can access the online modules

Exclusion Criteria:

* Are not the primary caregivers of a child between the ages of 2 to 16 years
* Are under the age of 18
* Are not English-speaking
* Do not have a reliable internet source or email address

Primary outcomes:
measure: Feeding Practices
timeFrame: 1 month
Secondary outcomes:
Other outcomes:
Locations:
city: University Park
country: United States
facility: Penn State
state: Pennsylvania
Study officials:
References:
Clinical trial NCT04725357: Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery?
Official title: A Randomized Comparison of Meloxicam to Opioids Following Arthroscopic Labrum Repairs of the Shoulder
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE3
Conditions: Shoulder Pain
Lead sponsor: Rothman Institute Orthopaedics
Sponsor class: OTHER
First posted: 2021-01-26
Enrollment: 96
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The opioid epidemic continues to be a major concern, with orthopedic surgeons being among the top prescribers of opioids. Studies evaluating these practices found that opioids are overprescribed, even for common procedures. Patients undergoing arthroscopic labrum repair of the shoulder were found to have an average of 20 pills left over after surgery. Many strategies have been developed to tackle overprescribing and have found success, including no opioid protocols for carpal tunnel release. The purpose of this study is to examine if meloxicam alone provides similar patient reported outcomes to opioids following arthroscopic labrum repair of the shoulder.


Eligibility criteria: Inclusion Criteria:

* Age ≥ 18
* Scheduled for arthroscopic labrum repair of the shoulder

Exclusion Criteria:

* History of opioid, acetaminophen, NSAID or local anesthetic allergy or intolerance, or contraindications to these medications.
* Currently on long-term preoperative narcotics
* Scheduled for revision arthroscopic repairs of the shoulder
* Unable/unwilling to consent for enrollment
* Unable to complete postoperative surveys
* History of chronic pain syndromes (fibromyalgia, chronic diffuse MSK pain, etc)
* Patients under the age of 18
* Pregnant or breastfeeding women
* Scheduled for concurrent procedures

Primary outcomes:
measure: Total Analgesic use
timeFrame: 14 days
measure: Postoperative Pain Control
timeFrame: 14 days
Secondary outcomes:
Other outcomes:
Locations:
city: Philadelphia
country: United States
facility: Rothman Orthopaedic Institute
state: Pennsylvania
Study officials:
References:
Clinical trial NCT05123157: Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort Study
Official title: Pattern and Type of Amputation and Mortality Rate Associated With Diabetic Foot in Jeddah, Saudi Arabia: A Retrospective Cohort Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Diabetic Foot
Amputation
Lead sponsor: King Abdulaziz University
Sponsor class: OTHER
First posted: 2021-11-17
Enrollment: 358
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: medical records of King Abdulaziz University Hospital (KAUH).

Brief summary: This study explored the pattern and type of amputations performed on patients with diabetic foot who were admitted to our institution, as well as the 7-year mortality rate of patients with diabetic foot at the same institution. We believe that our study makes a significant contribution to the literature because it highlights the need for strengthening efforts to decrease the risk of amputation and mortality among patients with diabetic foot, especially in Jeddah, Saudi Arabia.


Eligibility criteria: Inclusion Criteria:

* From the medical records of King Abdulaziz University Hospital (KAUH).

Exclusion Criteria:

* None

Primary outcomes:
measure: Rate and Pattern of amputation.
timeFrame: 7 years
measure: Mortality among patients with diabetic foot
timeFrame: 7 years
Secondary outcomes:
Other outcomes:
Locations:
city: Jeddah
country: Saudi Arabia
facility: Faculty of medicine
state: Makkah
Study officials:
References:
Clinical trial NCT06572657: Comparison of the Effects of Aerobic Exercise and Computerized Cognitive Stimulation in Patients With Schizophrenia - A Randomized Controlled Trial
Official title: Comparison of the Effects of Aerobic Exercise and Computerized Cognitive Stimulation in Patients With Schizophrenia - A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Schizophrenia
Exercise
Computerized Cognitive Stimulation
Lead sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital
Sponsor class: OTHER_GOV
First posted: 2024-08-27
Enrollment: 60
Sex: ALL
Minimum age (years): 20
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Schizophrenia is a chronic mental disorder characterized by the occurrence of both positive symptoms, such as hallucinations and delusions, and negative symptoms, such as apathy and withdrawal, repetition of cognitive skills and disorganization. There are approximately 20 million people with schizophrenia worldwide and this number will continue to increase every year.

Detailed description: The aim of this study was to compare the effects of computer-based cognitive stimulation and aerobic/strengthening exercises on cognition, physical capacity, depression, quality of life, quality of life, and activities of daily living in schizophrenia patients receiving community mental health center services.

Eligibility criteria: Inclusion Criteria:

* Individuals diagnosed with schizophrenia by a physician according to DSM-V criteria Patients treated at TRSM Individuals diagnosed with schizophrenia between the ages of 20-60

Exclusion Criteria:

* Those who did not give consent to participate in the study Patients with a diagnosis other than schizophrenia Pregnancy Patients with chronic metabolic diseases such as diabetes, heart problems and cancer

Primary outcomes:
measure: Montreal Cognitive Assessment Scale
timeFrame: 12 weeks
measure: International Physical Activity Questionnaire-Short Form
timeFrame: 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: İstanbul
country: Turkey
facility: Kartal Dr Lütfi Kırdar Şehir Hastanesi
Study officials:
References:
Clinical trial NCT01025557: Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response
Official title: The Effects of Isovolumetric and Isocaloric Preloads of Various Types of Milk on Food Intake, Subjective Appetite and Glycemic Response in Healthy Young Men and Women
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
PHASE2
Conditions: Diabetes Prevention
Obesity Prevention
Keywords: Food intake
Blood glucose
Milk
Lead sponsor: University of Toronto
Sponsor class: OTHER
Collaborators: name: Dairy Farmers of Ontario
name: Mondelēz International, Inc.
name: Natural Sciences and Engineering Research Council, Canada
First posted: 2009-12-03
Enrollment: 52
Sex: ALL
Minimum age (years): 20
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: The purpose of this protocol is to study the effects of fluid milk products on satiety, food intake, and glucose metabolism in healthy young men and women. Experiment 1: The specific objective is to investigate isovolumetric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, and water (control) on satiety and food intake and on blood glucose before and after a meal. A fixed volume approach is based on the commercially available serving size. Experiment 2 will examine equicaloric amounts of milk (2% M.F.), chocolate milk (1% M.F.), a soy beverage, cow's milk-based infant formula, a glucose drink and water (control) the treatments in order to investigate macronutrient composition on satiety and food intake and on blood glucose before and after the meal.


Eligibility criteria: Inclusion Criteria:

* Healthy
* Non-smoking
* Aged 20-30 years
* Body mass index between 20 and 24.9 kg/m2

Exclusion Criteria:

* Diabetes
* Medication
* Lactose-intolerance or allergies to milk
* Breakfast skippers and those on an energy restricted diet

Primary outcomes:
measure: Food intake
timeFrame: 30 minute
Secondary outcomes:
measure: Blood glucose
timeFrame: 0, 10, 20, 30, 50, 80, 110, 140 and 170 minutes
Other outcomes:
Locations:
city: Toronto
country: Canada
facility: University of Toronto
state: Ontario
Study officials:
affiliation: University of Toronto
name: Harvey Anderson, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: