Clinical trial NCT05613101: ESPB and ACB in Knee Arthroplasty
Official title: Comparison of the Effects of Ultrasound-Guided Erector Spinae Plane Block and Adductor Canal Block on Postoperative Pain, Opioid Consumption and Quadriceps Muscle Strength in Total Knee Arthroplasty Surgery
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Post Operative Pain
Keywords: Erector Spinae Plane Block
Adductor Canal Block
Total Knee Arthroplasty
Lead sponsor: Istanbul Medeniyet University
Sponsor class: OTHER
First posted: 2022-11-14
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Erector Plane Block Adductor Canal Block
Primary purpose: TREATMENT

Brief summary: Total knee arthroplasty surgery is preferred in the treatment of osteoarthritis and causes severe postoperative pain. In this study, we aimed to investigate the effects of lumbar erector spina plan block and adductor canal block on postoperative pain and quadriceps muscle strength in patients who underwent total knee arthroplasty with spinal anesthesia.

Detailed description: In a prospective, randomized study; Medeniyet University Faculty of Medicine Göztepe Prof. Dr. Forty patients who underwent total knee arthroplasty surgery at Süleyman Yalçın City Hospital were divided into two groups. After the surgery was completed, erector spina plane block was applied to Group E (n=20) patients with 20 ml of 0.25% bupivacaine from the operated side L3-L4 level, while in Group A (n=20) patients, in the area where the sartorius muscle crosses the adductor magnus muscle, it was lateral to the superficial femoral artery. Adductor canal block was applied to the adductor canal with 20 ml of 0.5% bupivacaine. All patients were administered 1 gr paracetamol and 75 mg diclofenac sodium when their pain started in the orthopedic ward. Numerical pain score and quadriceps muscle strength were evaluated during the 48-hour follow-up of the patients. When the pain score was 4 and above, 50 mg pethidine hydrochloride was administered.

Eligibility criteria: Inclusion Criteria:

* patients who underwent total knee arthroplasty surgery
* ASA I-III patients

Exclusion Criteria:

* Patients with coagulopathy
* Patients history with local anesthetic allergy or toxicity
* Patients with long hospital stay
* Patients with advanced organ failure
* Mental retarded patients
* Presence of infection at the injection site

Primary outcomes:
measure: Postoperative pain 30 minute
timeFrame: 30. min.
measure: Postoperative pain 1. hour
timeFrame: 1. hour
measure: Postoperative pain 2. hour
timeFrame: 2. hour
measure: Postoperative pain 6. hour
timeFrame: 6. hour
measure: Postoperative pain 12. hour
timeFrame: 12. hour
measure: Postoperative pain 24. hour
timeFrame: 24. hour
measure: Postoperative pain 36. hour
timeFrame: 36. hour
measure: Postoperative pain 48. hour
timeFrame: 48. hour
Secondary outcomes:
measure: Opioid consuption 30. min.
timeFrame: 30. min.
measure: Opioid consuption 1. hour
timeFrame: 1. hour
measure: Opioid consuption 2. hour
timeFrame: 2. hour
measure: Opioid consuption 6. hour
timeFrame: 6. hour
measure: Opioid consuption 12. hour
timeFrame: 12. hour
measure: Opioid consuption 24. hour
timeFrame: 24. hour
measure: Opioid consuption 36. hour
timeFrame: 36. hour
measure: Opioid consuption 48. hour
timeFrame: 48. hour
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medeniyet University Goztepe Suleyman Yalcın City Hospital
Study officials:
References: