Clinical trial NCT06220630: The Characteristics, Treatment Patterns and Prognosis of Chinese Male Breast Cancer: A Real-world Study
Official title: The Characteristics, Treatment Patterns and Prognosis of Chinese Male Breast Cancer: A Real-world Study
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Breast Cancer
Lead sponsor: First Affiliated Hospital, Sun Yat-Sen University
Sponsor class: OTHER
Collaborators: name: Beijing Medical Award Foundation
name: The Affiliated Cancer Hospital of Xinjiang Medical University
name: Hebei Medical University Fourth Hospital
name: The Third Affiliated Hospital of Kunming Medical University
name: Sun Yat-sen University
name: The Affiliated Cancer Hospital of Zhengzhou University
name: The Third Hospital of Nanchang City
name: Beijing 302 Hospital
name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
name: Fujian Provincial Hospital
name: First Hospital of China Medical University
name: The Affiliated Hospital of Qingdao University
name: Guangdong Provincial People's Hospital
name: First Affiliated Hospital Xi'an Jiaotong University
name: First People's Hospital of Foshan
name: Peking University First Hospital
name: The Affiliated Hospital Of Guizhou Medical University
name: Guangdong Provincial Hospital of Traditional Chinese Medicine
name: Jiangmen Central Hospital
name: The Second Affiliated Hospital, Guangzhou Medical University
name: The First Affiliated Hospital, Zhejiang University
name: Peking University Shenzhen Hospital
name: The Second Affiliated Hospital of Harbin Medical University
name: Affiliated Sanming First Hospital of Fujian Medical University
name: Jieyang People's Hospital
name: National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital
name: Shantou Central Hospital
name: The First Affiliated Hospital with Nanjing Medical University
name: Lianjiang Pepole's Hospital, Lianjiang
name: Guangdong Women and Children Hospital
name: Zhanjiang Central Hospital
name: Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine
First posted: 2024-01-24
Enrollment: 1200
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: All eligible cases were collected from a Chinese national database (Chinese Society of Clinical Oncology Breast Cancer database) and other involved centers.

Brief summary: The goal of this observational study is to investigate the features in Chinese male breast cancer (MBC) patients. The main question it aims to answer is:

* The characteristics, treatment patterns and prognosis of Chinese MBC patients. The clinicopathological characteristics, treatment information and follow-up data of participants will be extracted from a Chinese national database (Chinese Society of Clinical Oncology Breast Cancer database) and other involved Chinese centers.

Researchers will investigate the features, survival associated factors and other relevant factors of this population.

Detailed description: The goal of this observational study is to investigate the features in Chinese male breast cancer (MBC) patients. The main question it aims to answer is:

* The characteristics, treatment patterns and prognosis of Chinese MBC patients. The clinicopathological characteristics, treatment information and follow-up data of participants will be extracted from a Chinese national database (Chinese Society of Clinical Oncology Breast Cancer database) and other involved Chinese centers.

Researchers will investigate the features, survival associated factors and other relevant factors of this population.

The collected variables included: survival time, survival status, year of diagnosis, age, stage, molecular subtype statuses, histology, grade, and surgery, radiotherapy and systemic therapies utilization.

Eligibility criteria: Inclusion Criteria:

* Biological sex is male;
* Microscopically diagnosed as primary breast cancer.

Exclusion Criteria:

* Presence of skin-origin malignancy on the breast.

Primary outcomes:
measure: Overall survival
timeFrame: From the time of diagnosis to August 1, 2024 (anticipated).
Secondary outcomes:
Other outcomes:
Locations:
city: Guangzhou
country: China
facility: First affiliated hospital of Sun Yat-sen university
state: Guangdong
Study officials:
affiliation: 1st affiliated hospital of Sun Yat-sen university
name: Ying Lin, MD, PhD
role: PRINCIPAL_INVESTIGATOR
References: