Clinical trial NCT05383430: Prevalence of Stuttering in Children With ADHD at Sohag University Hospital
Official title: Prevalence of Stuttering in Children With ADHD at Sohag University Hospital
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: ADHD Children With Stuttering
Lead sponsor: Sohag University
Sponsor class: OTHER
First posted: 2022-05-20
Enrollment: 50
Sex: ALL
Minimum age (years): 6
Maximum age (years): 18
Standard ages: CHILD
ADULT
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: ADHD children with stuttering -: Cross sectional observational study. Period of the study: one year from the date of acceptance of the protocol.

Place of the study: at Neuropsychiatriy and Phoniatric units at Sohag University Hospital.

Brief summary: The majority of the latest research suggests that stuttering is associated with significantly elevated levels of trait and social anxiety. The prevalence of children who stutter and have attention deficit/ hyperactivity disorder (ADHD) ranges from 4 to 26%. About 10-20% of children who stutter might show ADHD.

Gender ( male) is the dominant risk factor for stuttering, as also applies to other neurodevelopmental disorders. Examples include attention deficit hyperactive disorder (ADHD), conduct disorder, tics and the Gilles de la Tourette syndrome (GTS). These neurodevelopmental disorders are the second -most prominent set of comorbidities with stuttering.

Attention-deficit hyperactivity disorder (ADHD) and stuttering share many characteristics in addition to temperament . A complex interplay of neural differences, with genetic and environmental components, has been reported as a possible cause of both disorders. In addition, both may appear more frequently in boys than in girls . Furthermore, it is emphasized that childhood stuttering can be accompanied by aspects of ADHD . Likewise, children exhibiting signs of ADHD more frequently display speech disfluencies than their peers.

It is suggested that children with stuttering and those without stuttering will display different profiles in terms of temperament, certain aspects of ADHD, and some types of anxiety. In addition, it is to be expected that there will be some correlations between these variables in children who stutter. However, it is not possible to draw definite conclusions about this issue that could be generalized to all children who stutter. Furthermore, there are very few studies that deal with combinations of these variables .


Eligibility criteria: Inclusion Criteria:

* All children with ADHD

Exclusion Criteria:

* 1-Children ageed below 6 years old. 2- children with ADHD with other behavioral and neurological disorders.

Primary outcomes:
measure: Prevalence of stuttering in ADHD children
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Sohag
country: Egypt
facility: Sohag University Hospital
Study officials:
References:
citation: Riley GD. A stuttering severity instrument for children and adults. J Speech Hear Disord. 1972 Aug;37(3):314-22. doi: 10.1044/jshd.3703.314. No abstract available.
citation: Healey EC, Reid R. ADHD and stuttering: a tutorial. J Fluency Disord. 2003 Summer;28(2):79-92; quiz 93. doi: 10.1016/s0094-730x(03)00021-4.
citation: Lan J, Song M, Pan C, Zhuang G, Wang Y, Ma W, Chu Q, Lai Q, Xu F, Li Y, Liu L, Wang W. Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese. J Hum Genet. 2009 Aug;54(8):457-60. doi: 10.1038/jhg.2009.60. Epub 2009 Jul 10.
citation: Verkuijl N, Perkins M, Fazel M. Childhood attention-deficit/hyperactivity disorder. BMJ. 2015 May 20;350:h2168. doi: 10.1136/bmj.h2168. No abstract available.