Clinical trial NCT05338840: Mulligan Rotational Movement Versus Medial Gapping Technique in Patients With Knee Osteoarthritis
Official title: Effects of Mulligan Rotational Movement Versus Medial Gapping Technique on Pain, Range of Motion and Disability in Patients With Knee Osteoarthritis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Knee Osteoarthritis
Keywords: Mulligan Rotational Movement
Medial Gapping Technique
Pain
Range of Motion
Knee Osteoarthritis
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2022-04-21
Enrollment: 40
Sex: ALL
Minimum age (years): 20
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Knee osteoarthritis is a progressive degenerative and non-inflammatory joint disorder. Due to the extensive use and stress placed on knee joint, it is a common site for painful disorders such as knee osteoarthritis. It is seen that medial side of knee is most commonly affected because of weight bearing on medial side. Symptomatically, the knee joint is most commonly affected in osteoarthritis because it requires support, high mobility, and insufficient internal stability. Osteoarthritis of the knee joint affects three parts of the knee joint (medial, lateral, and patellar-femoral joints) and develops slowly, usually over 10-15 years, interfering with daily activities Slow and gentle movements like Tai Chi, Isometric, iso-kinetic and isotonic exercises are considered helpful in increasing joint range of motion and physical function. Stretching and aquatic therapy can also decrease pain and enhance joint flexibility. The aim of this study is to compare the effects of Mulligan rotational movement vs Medial gapping technique on pain, range of motion and disability in knee osteoarthritis.

This study will be a randomized control trial and will be conducted in Riphah clinics and LGH. The study will be completed within the time duration of six months. Non-probability convenient sampling technique will be used to collect the data. Those who will meet the inclusion criteria will be recruited in the group. The sample size of patients with knee osteoarthritis will be taken in this study to find the effects of Mulligan Rotational movements vs. Medial gap technique, aged between 20-40 years, will be allocated to an intervention or control group. The scales used for recording findings will be goniometer, visual analogue scale and modified disability index. Subjects will randomly divide into control group called group A Taking Mulligan therapy and Interventional group called group B taking Median Gapping Technique. 12 sessions over 6 weeks were performed on both groups. Data analysis will be done by SPSS version 25.


Eligibility criteria: Inclusion Criteria:

* Post-traumatic stiffness of knee
* Restricted range of knee flexion
* Patients with restricted ROM and with Grade 3 or more than three power of knee muscle

Exclusion Criteria:

* Patients with hyper mobile and unstable joints
* Joint infection and loosening,
* Soft tissue injuries around knee joints and
* Other complications of post-fracture

Primary outcomes:
measure: NPRS
timeFrame: 6 weeks
measure: GONIOMETR
timeFrame: 6 weeks
measure: Disability Index Scale
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Riphah Rehabilitation Center
state: Punjab
Study officials:
affiliation: Riphah International University
name: hina gul, t-DPT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Lespasio MJ, Piuzzi NS, Husni ME, Muschler GF, Guarino A, Mont MA. Knee Osteoarthritis: A Primer. Perm J. 2017;21:16-183. doi: 10.7812/TPP/16-183.
citation: Lalnunpuii A, Sarkar B, Alam S, Equebal A, Biswas A. Efficacy of mulligan mobilisation as compared to Maitland mobilisation in females with knee osteoarthritis: a double blind randomized controlled trial. International Journal of Therapies and Rehabilitation Research. 2017;6(2):37.
citation: Nazir SNB, Rathore FA. Efficacy of Mulligan joint mobilizations and trunk stabilization exercises versus isometric knee strengthening in the management of knee osteoarthritis: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2024 May 7;16(1):105. doi: 10.1186/s13102-024-00893-7.
citation: Mehmood Z, Anwar N, Tauqeer S, Shabbir M, Khalid K, Mehmood S. Comparison of Maitland Mobilization and Mulligan Mobilization with Movement in Knee Osteoarthritis Patients. Pakistan Journal of Medical Research. 2021;60(3):126-30
citation: Rao RV, Balthillaya G, Prabhu A, Kamath A. Immediate effects of Maitland mobilization versus Mulligan Mobilization with Movement in Osteoarthritis knee- A Randomized Crossover trial. J Bodyw Mov Ther. 2018 Jul;22(3):572-579. doi: 10.1016/j.jbmt.2017.09.017. Epub 2017 Sep 28.
citation: Epskamp S, Dibley H, Ray E, Bond N, White J, Wilkinson A, et al. Range of motion as an outcome measure for knee osteoarthritis interventions in clinical trials: an integrated review. Physical Therapy Reviews. 2020;25(5-6):462-81.