Clinical trial NCT05750160: Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome
Official title: The Effect of Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Healthcare Workers With Burnout Syndrome
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Burnout Syndrome
Neutrophil-Lymphocyte Ratio
Interleukin-6
Interleukin-10
Lead sponsor: Indonesia University
Sponsor class: OTHER
First posted: 2023-03-01
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Burnout Syndrome (BOS) can be defined as a state of stress both physically and psychically due to the burden and stressor of high work. The prevalence of BOS in health workers varies between 25-75% globally. Studies have shown that the presence of Burnout syndrome will meaningfully reduce the quality of services related to patient safety and cause immune system disorders that act as the body's defense against viral, bacterial, protozoal and fungal infections. Many strategies have been researched to help prevent and reduce the occurrence of Burnout syndrome, one of which is music therapy. The purpose of this study was to determine the effect of music therapy on the immune response in health workers with Burnout Syndrome.

This study is a randomized clinical trial with a pre and post test control group design for health workers at Dr Kariadi General Hospital and Dr. Cipto Mangunkusumo General Hospital. Subjects will be provided with information prior to the study and asked to sign an informed consent sheet if they agree to be involved in the study. Subjects will be divided into control groups and treatment groups with matching age, gender and type of work. In the treatment group, music therapy will be given as much as 3 times a week for 4 weeks. Data were taken on both groups before and after the intervention. This study used the Maslach Burnout Inventory Human Service Survey (MBI-HSS) and blood laboratory examination to determine the value of the Neutrophyl Lymphocyte Ratio, Interleukin 6 and Interleukin 10 levels.


Eligibility criteria: Inclusion Criteria:

1. Age 18 years - 60 years old
2. Health workers in the wards and polyclinic of Dr. Cipto Mangunkusumo Hospital or Dr. Kariadi Hospital, including doctors in charge of patients, nurses, residents, and other supporting health workers
3. Included in the Burnout syndrome criteria from the Maslach Burnout Inventory-Human Service Survey questionnaire

Exclusion Criteria:

1. Refusing to follow the study
2. Have a history of heart disease, kidney disease, diabetes, cancer, tuberkulosis, autoimmune, immunodeficiency
3. Taking drugs that affect the central nervous system or immunosuppressants
4. Have hearing disorder
5. Have a psychiatric disorder
6. Being pregnant
7. Healthcare workers who don't like music

Primary outcomes:
measure: Burnout syndrome
timeFrame: change from baseline score at 4 weeks
measure: Neutrophil Lymphocyte Ratio
timeFrame: Change from baseline Neutrophil Lymphocyte Ratio at 4 weeks
measure: Interleukin 6
timeFrame: Change from baseline Interleukin-6 level at 4 weeks
measure: Interleukin 10
timeFrame: Change from baseline Interleukin-10 level at 4 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Jakarta
country: Indonesia
facility: Cipto Mangunkusumo National Hospital
Study officials:
References: