Clinical trial NCT04508504: PENG Block for Arthroscopic Hip Surgery
Official title: Pericapsular Nerve Group (PENG) Block for Arthroscopic Hip Surgery: A Randomized, Placebo-controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Postoperative Pain
Hip Arthroscopy
Keywords: pericapsular nerve group block, PENG, hip arthroscopy, pain
Lead sponsor: University of Virginia
Sponsor class: OTHER
First posted: 2020-08-11
Enrollment: 70
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomized, double blind, placebo controlled
Primary purpose: TREATMENT

Brief summary: This randomized, double-blinded, placebo-controlled trial seeks to evaluate the analgesic efficacy of the pericapsular nerve group block in the setting of outpatient hip arthroscopy.

Detailed description: The pericapsular nerve group, or PENG block, has been recently described and shows promise in providing analgesia to the hip joint. The analgesic value of this block in the setting of hip arthroscopy is unknown. This study aims to compare a preoperative PENG block to placebo block prior to outpatient hip arthroscopy under general anesthesia. The primary outcome measure is immediate postoperative pain as measured by numerical rating score in the post-anesthesia care unit (PACU). Secondary outcomes include opioid consumption, opioid-related adverse events, patient satisfaction, chronic opioid usage, and pain scores at other time points.

Eligibility criteria: Inclusion Criteria:

* Patients \> 18 years old undergoing unilateral hip arthroscopy at the outpatient surgery center.

Exclusion Criteria:

* refusal to participate
* \< 18 yo
* Chronic opioid use
* localized infection

Primary outcomes:
measure: PACU pain score
timeFrame: Within 30 minutes of emergence from anesthesia.
Secondary outcomes:
measure: PACU opioid consumption
timeFrame: Beginning with emergence from anesthesia and ending with discharge from the post-anesthesia care unit (typically 2 hours).
measure: Nausea and Vomiting
timeFrame: Beginning with emergence from anesthesia and ending with discharge from the post-anesthesia care unit (typically 2 hours).
measure: Patient satisfaction with analgesia
timeFrame: Determined through follow-up calls at 24 hours and 48-hours.
measure: Postoperative opioid utilization
timeFrame: Determined through follow-up calls at 24 hours, 48 hours, and 1 week postoperatively
measure: Postoperative pain scores
timeFrame: Determined through follow-up calls at 24 hours, 48 hours, and 1 week postoperatively
Other outcomes:
Locations:
city: Charlottesville
country: United States
facility: UVA Outpatient Surgery Center
state: Virginia
Study officials:
affiliation: University of Virginia
name: Peter E Amato, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.
citation: Amato PE, Coleman JR, Dobrzanski TP, Elmer DA, Gwathmey FW Jr, Slee AE, Hanson NA. Pericapsular nerve group (PENG) block for hip arthroscopy: a randomized, double-blinded, placebo-controlled trial. Reg Anesth Pain Med. 2022 Aug 23:rapm-2022-103907. doi: 10.1136/rapm-2022-103907. Online ahead of print.