Clinical trial NCT03165357: Sodium Bicarbonate Supplementation in Athletes
Official title: The Effect of Sodium Bicarbonate Supplementation on Physical Capacity and Body Composition in Trained Athletes
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Supplementation
Sport
Keywords: Crossfit
Sodium bicarbonate
Physical capacity
Lead sponsor: Poznan University of Life Sciences
Sponsor class: OTHER
Collaborators: name: Poznan University of PhysED
First posted: 2017-05-24
Enrollment: 26
Sex: ALL
Minimum age (years): 20
Maximum age (years): 43
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: TREATMENT

Brief summary: The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Detailed description: Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Eligibility criteria: Inclusion Criteria:

* written consent to participate,
* a current medical clearance to practice sports,
* training experience: at least 2 years (of CrossFit training),
* minimum of 3 workout sessions (CrossFit) a week,
* 20-43 years.

Exclusion Criteria:

* current injury,
* any health-related contraindication,
* declared general feeling of being unwell,
* unwilling to follow the study protocol.

Primary outcomes:
measure: Changes in aerobic capacity after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in specific performance capacity after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
Secondary outcomes:
measure: Changes in fat mass and fat free mass after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes in blood hematocrit levels after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
measure: Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementation
timeFrame: Baseline and after 10 days
Other outcomes:
Locations:
city: Poznań
country: Poland
facility: Poznan University of Life Sciences, ul.Wojska Polskiego 31
state: Wielkopolska
Study officials:
affiliation: Department of Hygiene and Human Nutrition, Poznan University of Life Sciences, Poznan, Poland
name: Jan Jeszka, Professor
role: STUDY_CHAIR
References: