Clinical trial NCT06770660: Effect of Tele-exercise on Cardiorespiratory Fitness in Paediatrics
Official title: Evaluating the Effectiveness of Telemedicine-based Exercise Programme in Improving Cardiorespiratory Fitness in Asian Paediatric Population: a Randomised Controlled Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Cardiorespiratory Fitness
Insulin Resistance
Keywords: paediatric
cardiorespiratory fitness
telemedicine
insulin resistance
Lead sponsor: KK Women's and Children's Hospital
Sponsor class: OTHER_GOV
First posted: 2025-01-13
Enrollment: 122
Sex: ALL
Minimum age (years): 12
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The goal of this clinical trial is to learn if telemedicine exercise programme can improve the cardiorespiratory fitness (how well your body delivers oxygen to muscles and organs) and insulin resistance in Asian children with low cardiorespiratory fitness levels. The main questions it aims to answers are:

* Does telemedicine exercise programme improve the number of 20-metre laps the participant is able to run?
* Does telemedicine exercise programme improve the insulin sensitivity using the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) formula?

Researchers will compare the telemedicine exercise programme to current active lifestyle programme (e.g., daily step count monitoring) to see if telemedicine exercise programme is more effective in improving cardiorespiratory fitness.

Participants will:

* participate in weekly telemedicine exercise programme or adhere to current active lifestyle recommendations through daily step count reporting for 10 weeks
* visit the clinic for pre- and post-programme cardiorespiratory fitness assessments and blood taking

Detailed description: This study is to investigate the effectiveness of delivering exercise intervention programme to improve cardiorespiratory fitness through telemedicine for paediatric patients with low cardiorespiratory fitness levels. Conventionally, exercise programme for these patients are conducted within hospital premises. However, some challenges may deter patients from enrolling into these programmes, such as long travelling distance, lack of available caregiver and unsuitable timings. Understanding the impact of a shorter-term programme (i.e., 10-week programme) on cardiorespiratory fitness and glucose metabolism also allows us to customise programmes of appropriate length to deliver the require health impact instead of subjecting all patients to a lengthy programme. Therefore, evaluating the effectiveness of telemedicine-based exercise programme will enable us to fine-tune our programme and provide an alternative mode of exercise intervention so as to cater for a wider range of paediatric patients.

Eligibility criteria: Inclusion Criteria:

* 12 to 17 years (secondary school students)
* able to participate in school physical education lessons

Exclusion Criteria:

* less than 12 years or older than 17 years (non-secondary school students)
* has medical or musculoskeletal condition(s) preventing participation in school physical education lessons or exercise

Primary outcomes:
measure: Cardiorespiratory fitness assessment
timeFrame: At the end of 10-week programme
Secondary outcomes:
measure: Insulin resistance
timeFrame: At the end of the 10-week programme
Other outcomes:
Locations:
city: Singapore
country: Singapore
facility: KK Women's and Children's Hospital
Study officials:
affiliation: KK Women's and Children's Hospital
name: Benny Loo
role: PRINCIPAL_INVESTIGATOR
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