Clinical trial NCT06929104: Psychological Problems in Post Thyroidectomy Patients
Official title: Psychological Problems and Associated Factors in Patients With Thyroidectomy in Assiut University Hospitals
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Post-Thyroidectomy Hypoparathyroidism
Lead sponsor: Assiut University
Sponsor class: OTHER
First posted: 2025-04-16
Enrollment: 127
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients undergo thyroidectomy

Brief summary: Quality of life (QoL) refers to perceived well-being, and encompasses the evaluation of physical health, and physical, social, and psychological functioning .

The assessment of quality of life (QOL) post-thyroidectomy has gained significant attention in the medical community. Multiple studies have delved into the long-term consequences of thyroidectomy, aiming to evaluate the impact on patients' overall well-being and functional status. By examining numerous aspects, such as the physical, psychological, and social dimensions of QOL, researchers have provided valuable insights into the outcomes of thyroidectomy, hence contributing to improving patient care and enhancing their postoperative experiences.

Detailed description: Regarding the psychological dimension of QOL, several studies have emphasized patients' emotional well-being post-thyroidectomy. Findings have demonstrated that, while many individuals experience temporary emotional disturbances related to the surgery, long-term psychological outcomes generally improve over time. In fact, the majority of patients report higher levels of self-esteem and body image post-thyroidectomy, as the removal of a diseased or abnormal thyroid gland can alleviate anxiety and distress associated with the underlying condition. However, additional research is needed to explore the specific factors contributing to these positive psychological outcomes and to identify potential interventions for those experiencing psychological distress following thyroidectomy .

Thyroidectomy is the treatment of choice in thyroid cancer patients, and the prevalence of thyroid cancer has shown a gradual increase over the past two decades. Thyroid surgery is also indicated in certain forms of benign thyroid disorder, such as nontoxic goiter and Graves' disease. Although thyroidectomy is a universal operation, few studies to date have investigated the impact of thyroidectomy on QOL .

Eligibility criteria: Inclusion Criteria:

* 1-Gender: both males and females 2- Post thyroidectomy patients: patients who will be planned to undergo different types of thyroidectomy for conditions such as thyroid cancer, benign thyroid disease (goiter), or hyperthyroidism (e.g., Graves' disease) and admitted as inpatients.

  3- Age Range: participants within certain age range (e.g., 18-75 years). 4-Consent: Ability to provide informed consent to participate in the study. 5-Stable Medical Condition:

Exclusion Criteria:

1. Patients who were previously diagnosed with any psychiatric diseases.
2. Medications: Use of medications that could affect outcome of the study e.g., antidepressants, corticosteroids and benzodiazepines
3. Pregnancy: Current pregnancy or breastfeeding.
4. Age: less than 18 years or more than 75 years old.
5. patients with any organ failure e.g (heart failure, end-stage renal disease requiring dialysis and liver failure) and cancers other than thyroid cancer.

Primary outcomes:
measure: To assess the prevalence of psychological problems e.g., depression, anxiety and fatigue in patients with post thyroidectomy surgery in Assiut University hospitals.
timeFrame: One year
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References: