Clinical trial NCT06024148: Continuation of Anti-osteoporotic Treatment 1 Year After Initial Administration
Official title: Evaluation of the Continuation of Anti-osteoporotic Treatment 1 Year After Initial Administration Following Severe Osteoporotic Fracture in Patients Aged 75 and Over, Hospitalized at the Rocheplane Medical Center
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Osteoporosis Fracture
Keywords: antiosteoporotic treatment
professional practice assessment
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
First posted: 2023-09-06
Enrollment: 250
Sex: ALL
Minimum age (years): 75
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: We will include the number of patients corresponding to the "patient flow" admitted to CMR's units of interest over one year, and, corresponding to the inclusion criteria (CMR welcomes 250 patients aged 75 and over to its geriatric units each year, all types of fractures combined; ¾ of patients are admitted for severe fractures).

Brief summary: The aim of this observational study is to assess the obstacles and levers to the continuation of anti-osteoporotic treatment, and to identify those where action could be taken to improve the quality of care for fractured patients.

The individual and collective stakes are high. Fracture is the most feared complication of osteoporosis. The current under-diagnosis and under-treatment of this chronic pathology exposes patients to a high risk of early re-fracture, with the associated morbidity and mortality.

General practitioners have a major role to play in monitoring and coordinating patients' healthcare pathways. The aim of this study is to assess ways of improving osteoporosis management in order to improve quality of life and disability-free life expectancy for individual patients. The public health and economic stakes are equally high. It is by identifying the obstacles that prospective work on the key elements to be implemented could help optimize osteoporosis management.

Detailed description: Selection of patients hospitalized at the Rocheplane Medical Center between June 2021 and May 2022, following a severe osteoporotic fracture and having received a first dose of antiosteoporotic treatment during their overall stay (initial admission department + CMR).

Sending of an information letter and request for non-objection from patients or their trusted support person, with a 1-month cooling-off period to express opposition.

Collection of variables of interest from CMR patients' medical records, followed by administration of a telephone hetero-questionnaire (transferred to Excel) to patients or their families 1 year after fracture occurrence.

If the patient or family did not answer the questionnaire, or if it was incomplete (missing data), the information could be sought by telephone from the attending physician.

Eligibility criteria: Inclusion Criteria:

* Hospitalization in CMR's Geriatric Rehabilitation Department between 01/06/2021 and 31/05/2022
* Age: 75 and over
* Admitted with severe post-fracture osteoporosis
* Having received a first dose of antiosteoporotic treatment between the day the fracture occurred and discharge from CMR (either in an inpatient unit prior to CMR, or at CMR)

Exclusion Criteria:

* Having objected to the use of his/her data for research purposes
* Subject under guardianship or deprived of liberty.
* Pathological fracture
* Anti-osteoporotic treatment prior to fracture
* 1-year follow-up made impossible by lack of contact with patient, family or attending physician.

Primary outcomes:
measure: Evaluate the rate of continuation of anti-osteoporotic treatment at 1 year after initial administration following a severe osteoporotic fracture in patients aged 75 and over.
timeFrame: Telephone data collection one year after Geriatric Rehabilitation Department stay
Secondary outcomes:
measure: Determine the rate of introduction of anti-osteoporotic treatment during the patient's overall stay
timeFrame: Medical records collected one year after Geriatric Rehabilitation Department stay
measure: Identify patient-related obstacles and levers to treatment renewal at 1 year after fracture
timeFrame: Telephone data collection one year after Geriatric Rehabilitation Department stay
measure: Determine the obstacles and levers to the continuation of treatment at 1 year after a fracture, in relation to the treating physician.
timeFrame: Telephone data collection one year after Geriatric Rehabilitation Department stay
measure: Determine the obstacles and levers to the continuation of treatment at 1 year for fractures related to the healthcare system
timeFrame: Telephone data collection one year after Geriatric Rehabilitation Department stay
measure: Evaluation of the professional practices of general practitioners concerning the management of osteoporosis.
timeFrame: Telephone data collection one year after Geriatric Rehabilitation Department stay of their patient
Other outcomes:
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