Clinical trial NCT06832891: Patient Preferences in Empathetic Communication by AI vs Human Authorship
Official title: A Survey of Patient Preferences on Empathetic Communication in Outpatient Palliative Care
Study type: OBSERVATIONAL
Overall status: ENROLLING_BY_INVITATION
Conditions: Preference, Patient
Keywords: AI
Lead sponsor: Mayo Clinic
Sponsor class: OTHER
First posted: 2025-02-18
Enrollment: 200
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients over the age of 18 being seen in palliative care clinic who have already established care and with diagnosis of any malignancy

Brief summary: This study aims to evaluate whether patients have different preference patterns for empathetic communication through AI vs human-being when knowledge of authorship is known vs blinded.

Detailed description: Hypothesis:

Patients will express increased preference for human-generated empathetic communication vs AI-generated empathetic communication when they are made aware of authorship vs when blinded to it.

Aims, purpose, or objectives:

Evaluate if patients have different preference patterns for empathetic communication through AI vs human-being when knowledge of authorship is known vs blinded

Background:

Artificial intelligence (AI) is rapidly gaining a foothold in the healthcare industry. AI's role in healthcare can largely be divided into two sets of tasks: Those which involve direct interaction with patients and those which do not. Many tasks which do not directly interact with patients, such as monitoring and resupplying medications, delivering goods across a hospital, and analyzing practice trends and outcomes are highly likely to benefit from the efficiency, cost-savings, and consistency AI can provide. Tasks involving direct patient interaction are considerably more controversial. Understanding of how patients will respond to AI communication remains quite limited which is concerning considering the rapid expansion of AI into the healthcare space. A logical first step to investigate is to see if patients react to AI communication when they are blinded to it vs when authorship is known. This concept has previously been tested in other industries such as business and the law, but patient communication preference in healthcare has been little studied, especially in palliative care. It is the aim of this study to investigate this.

Eligibility criteria: Inclusion Criteria:

* Patients over the age of 18 being seen in palliative care clinic who have already established care and with diagnosis of any malignancy

Exclusion Criteria:

* Inability to consent defined as: Acute mental status changes (delirium/encephalopathy), acute substance intoxication, intellectual disability, dementia, patient with active legal guardian
* Major psychiatric disorders including, but not limited to, bipolar disorder, psychotic disorders, active substance use disorder, and patients with active suicidal or homicidal thoughts.

  * NOTE: Patients with history of normal grieving reactions, major unipolar depressive disorder, posttraumatic stress disorder or generalized anxiety disorder would NOT be excluded.
* Inability to read in English

Primary outcomes:
measure: Preference patterns for empathetic communication
timeFrame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Rochester
country: United States
facility: Mayo Clinic in Rochester
state: Minnesota
Study officials:
affiliation: Mayo Clinic in Rochester
name: April Christensen, MD, MS
role: PRINCIPAL_INVESTIGATOR
References: