Clinical trial NCT06606743: Interval Training and Parkinson's Disease
Official title: The Comparative Impacts of High-Intensity Interval Training and Power Training on Heart Rate Variability, Gait, and Functional Performance in Patients With Parkinson's Disease
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Other Disorders of Autonomic Nervous System
Keywords: Interval Training
Resistance Training
Lead sponsor: University of Miami
Sponsor class: OTHER
First posted: 2024-09-23
Enrollment: 39
Sex: ALL
Minimum age (years): 30
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This research is designed to compare the impact of high-intensity interval training and high-velocity circuit resistance training on heart rate variability, gait, and functional performance in patients with Parkinsons disease.


Eligibility criteria: Inclusion Criteria:

1. Confirmed diagnosis of Parkinson's disease
2. Between the ages of 30-90 years of age;
3. Movement Disorder Society-Unified Parkinson's Disease Rating Scale ≤2, which will be provided by the participant's medical provider and be evaluated within 1 year of the study's inception.

Exclusion Criteria:

1. Uncontrolled cardiovascular disease that prevents participation in a training program
2. Documented HIV infection or another immunodeficiency syndrome
3. Other neuromuscular diseases besides Parkinson's disease
4. Current musculoskeletal injury that prevents exercise.
5. Having a pacemaker or other internal medical devices

Primary outcomes:
measure: Changes in Heart Rate Variability
timeFrame: Baseline, 10 weeks
measure: Changes in the Six-Minute Walk Test
timeFrame: Baseline, 10 weeks
measure: Changes in the Ten-Meter Walk Test
timeFrame: Baseline, 10 weeks
measure: Changes in the Five Times Sit-to-Stand Test
timeFrame: Baseline, 10 weeks
measure: Changes in Heart Rate Recovery
timeFrame: Baseline, 10 weeks
measure: Changes in One Repetition Maximum Strength
timeFrame: Baseline, 10 weeks
measure: Changes in Neuromuscular Power Testing
timeFrame: Baseline, 10 weeks
measure: Changes in Swing time of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Stance Time of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Double Support time of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Step Time of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Cadence of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Stride Length of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Step Length of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in speed of Gait
timeFrame: Baseline, 10 weeks
measure: Changes in Stride Width of Gait
timeFrame: Baseline, 10 weeks
Secondary outcomes:
measure: Changes in the Parkinson's Disease Questionnaire-39
timeFrame: Baseline, 10 weeks
measure: Non-Motor Symptoms Scale for Parkinson's Disease
timeFrame: Baseline, 10 weeks
Other outcomes:
Locations:
city: Coral Gables
country: United States
facility: University of Miami
state: Florida
city: Coral Gables
country: United States
facility: Laboratory of Neruomuscular Research and Active Aging
state: Florida
Study officials:
affiliation: University of Miami
name: Joseph F. Signorile, PhD
role: PRINCIPAL_INVESTIGATOR
References: