Clinical trial NCT00158340: Guided Self-Help Treatment for Binge Eating Disorder
Official title: Binge Eating Self-Guided Treatment (BEST)
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Eating Disorders
Bulimia
Keywords: Binge Eating
Overeating
Compulsive Eating
Hyperphagia
Lead sponsor: Kaiser Permanente
Sponsor class: OTHER
Collaborators: name: National Institute of Mental Health (NIMH)
First posted: 2005-09-12
Enrollment: 284
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study will determine the effectiveness of guided self-help treatment in treating individuals with binge eating disorder (BED).

Detailed description: Binge eating disorder (BED) is a serious condition characterized by compulsive overeating and feelings of powerlessness. The condition often has a negative impact on both physical and emotional health. This study will examine ways to help people determine whether they have BED and will test whether guided self-help (GSH) treatment is effective in treating BED.

Participants will be randomly assigned to receive either GSH treatment or usual clinical care (which may include general support and talk therapy) for 3 months. The GSH treatment is a cognitive behavioral therapy-based program that will be administered over 8 sessions. Participants receiving GSH will be given a book that focuses on dealing with BED; they will also meet with a therapist regularly to have their progress monitored. The Eating Disorders Examination (EDE), self-reports, questionnaires, and surveys will be used to assess participants. Assessments will be conducted at study entry, at Weeks 2 and 4 of the treatment, at the end of the treatment, and at 6 and 12 months post-treatment.

Eligibility criteria: Inclusion Criteria:

* Diagnosis of binge eating disorder (BED) bulimia nervosa (BN), or spectrum BN, defined as recurrent binge eating at least once a week for 3 months
* Body mass index (BMI) between 18 and 45
* Continuous membership in the Kaiser Permanente Northwest Division for at least 12 months prior to study entry

Exclusion Criteria:

* Diagnosis of anorexia nervosa or psychotic disorder
* Significant organic brain syndromes, retardation, pervasive developmental disorder, or autism
* At risk for suicide
* Pregnancy

Primary outcomes:
measure: Frequency of binge eating
timeFrame: Measured at post-treatment, Week 12, Month 6, and Year 1
Secondary outcomes:
measure: Frequency of inappropriate compensatory behaviors, dietary restraint, over-valuation of weight/shape, functional impairment, self-esteem, and social impairment
timeFrame: Measured at post-treatment, Week 12, Month 6, and Year 1
measure: Body weight
timeFrame: Measured at post-treatmentand Year 1
Other outcomes:
Locations:
city: Middletown
country: United States
facility: Wesleyan University Department of Psychology
state: Connecticut
city: Portland
country: United States
facility: Kaiser Permanente Center for Health Research
state: Oregon
Study officials:
affiliation: Wesleyan University
name: Ruth H. Striegel-Moore, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Lynch FL, Striegel-Moore RH, Dickerson JF, Perrin N, Debar L, Wilson GT, Kraemer HC. Cost-effectiveness of guided self-help treatment for recurrent binge eating. J Consult Clin Psychol. 2010 Jun;78(3):322-33. doi: 10.1037/a0018982.