Clinical trial NCT00812357: Symbicort Usage in Asthma Treatment and Impact of a New Therapeutic Strategy on Compliance and Asthma Control in France
Official title: Descriptive Pharmacoepidemiological Study on the Use of Symbicort Turbuhaler in the Treatment of Asthma in France and Impact of a New Therapeutic Strategy on the Compliance and Control of Asthma
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Asthma
Keywords: Symbicort Turbuhaler
asthma
cohort study
France
Lead sponsor: AstraZeneca
Sponsor class: INDUSTRY
First posted: 2008-12-22
Enrollment: 579
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Community sample

Brief summary: Descriptive pharmacoepidemiological study on the use of Symbicort Turbuhaler in the treatment of asthma in France and impact of a new therapeutic strategy on the compliance and control of asthma


Eligibility criteria: Inclusion Criteria:

* Asthmatic patients treated for this disease with Symbicort Turbuhaler
* Patients monitored for asthma by the doctor for at least 12 months
* Patients seen in outpatient care at the baseline visit
* Patients agreeing to participate in the study

Exclusion Criteria:

* Patients with any chronic lower respiratory disease other than asthma
* Patients receiving anti-IgE agents in the last 4 months
* Patients receiving desensitisation treatment outside of the maintenance phase
* Patients deemed to be unable to respond to the study for linguistic or cognitive reasons

Primary outcomes:
measure: Level of control of the asthma
timeFrame: 3 months
measure: Evaluation of compliance with treatment
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Dessenheim
country: France
facility: Research Site
state: Alsace
city: Duppigheim
country: France
facility: Research Site
state: Alsace
city: Haguenau
country: France
facility: Research Site
state: Alsace
city: Obernai
country: France
facility: Research Site
state: Alsace
city: Schiltigheim
country: France
facility: Research Site
state: Alsace
city: Strasbourg
country: France
facility: Research Site
state: Alsace
city: Bordeaux Cedex
country: France
facility: Research Site
state: Aquitaine Nord
city: Bordeaux
country: France
facility: Research Site
state: Aquitaine Nord
city: Boutiers St Trojan
country: France
facility: Research Site
state: Aquitaine Nord
city: Bruges
country: France
facility: Research Site
state: Aquitaine Nord
city: Le Bouscat
country: France
facility: Research Site
state: Aquitaine Nord
city: Saujon
country: France
facility: Research Site
state: Aquitaine Nord
city: Hinx
country: France
facility: Research Site
state: Aquitaine Sud
city: Saugnac Et Cambran
country: France
facility: Research Site
state: Aquitaine Sud
city: Aire Sur La Lys
country: France
facility: Research Site
state: Artois
city: Bruay La Buissiere
country: France
facility: Research Site
state: Artois
city: Marles Les Mines
country: France
facility: Research Site
state: Artois
city: Ste Austreberthe
country: France
facility: Research Site
state: Artois
city: Aix En Othe
country: France
facility: Research Site
state: Aube Franche Comte
city: Belfort
country: France
facility: Research Site
state: Aube Franche Comte
city: Epinal
country: France
facility: Research Site
state: Aube Franche Comte
city: Hericourt
country: France
facility: Research Site
state: Aube Franche Comte
city: Montrond Le Chateau
country: France
facility: Research Site
state: Aube Franche Comte
city: Roulans
country: France
facility: Research Site
state: Aube Franche Comte
city: Cournon D Auvergne
country: France
facility: Research Site
state: Auvergne Stephanois
city: Le Puy En Velay Cedex
country: France
facility: Research Site
state: Auvergne Stephanois
city: Pierre Benite Cedex
country: France
facility: Research Site
state: Auvergne Stephanois
city: St Etienne
country: France
facility: Research Site
state: Auvergne Stephanois
city: Caen
country: France
facility: Research Site
state: Basse Normandie
city: Colleville Montgomery
country: France
facility: Research Site
state: Basse Normandie
city: Lisieux Cedex
country: France
facility: Research Site
state: Basse Normandie
city: St Martin Des Champs
country: France
facility: Research Site
state: Basse Normandie
city: Dijon
country: France
facility: Research Site
state: Bourgogne
city: Fontaine Les Dijon
country: France
facility: Research Site
state: Bourgogne
city: Le Creusot
country: France
facility: Research Site
state: Bourgogne
city: Laval
country: France
facility: Research Site
state: Bretagne Nord
city: Loudeac Cedex
country: France
facility: Research Site
state: Bretagne Nord
city: Rennes Cedex 9
country: France
facility: Research Site
state: Bretagne Nord
city: Brest
country: France
facility: Research Site
state: Bretagne Sud
city: Vannes
country: France
facility: Research Site
state: Bretagne Sud
city: Athis Mons
country: France
facility: Research Site
state: Brie
city: Corbeil Essonnes Cedex
country: France
facility: Research Site
state: Brie
city: Creteil Cedex
country: France
facility: Research Site
state: Brie
city: Draveil
country: France
facility: Research Site
state: Brie
city: Ferolles Attilly
country: France
facility: Research Site
state: Brie
city: Yerres
country: France
facility: Research Site
state: Brie
city: Bedarieux
country: France
facility: Research Site
state: Catalogne
city: Beziers
country: France
facility: Research Site
state: Catalogne
city: Bouzigues
country: France
facility: Research Site
state: Catalogne
city: Caunes Minervois
country: France
facility: Research Site
state: Catalogne
city: Narbonne
country: France
facility: Research Site
state: Catalogne
city: Perpignan
country: France
facility: Research Site
state: Catalogne
city: Serignan
country: France
facility: Research Site
state: Catalogne
city: St Andre de Sangonis
country: France
facility: Research Site
state: Catalogne
city: Chalons En Champagne Cedex
country: France
facility: Research Site
state: Champagne Ardennes
city: Reims Cedex
country: France
facility: Research Site
state: Champagne Ardennes
city: Reims
country: France
facility: Research Site
state: Champagne Ardennes
city: Chatellerault
country: France
facility: Research Site
state: Charente
city: La Tranche Sur Mer
country: France
facility: Research Site
state: Charente
city: Niort
country: France
facility: Research Site
state: Charente
city: Poitiers Cedex
country: France
facility: Research Site
state: Charente
city: Poitiers
country: France
facility: Research Site
state: Charente
city: Rochefort Cedex
country: France
facility: Research Site
state: Charente
city: Royan
country: France
facility: Research Site
state: Charente
city: Thure
country: France
facility: Research Site
state: Charente
city: Chambery
country: France
facility: Research Site
state: Dauphine
city: Grenoble
country: France
facility: Research Site
state: Dauphine
city: La Tronche
country: France
facility: Research Site
state: Dauphine
city: Metz Tessy
country: France
facility: Research Site
state: Dauphine
city: St Martin D Heres
country: France
facility: Research Site
state: Dauphine
city: Antibes
country: France
facility: Research Site
state: Esterel
city: Cagnes Sur Mer
country: France
facility: Research Site
state: Esterel
city: Draguignan
country: France
facility: Research Site
state: Esterel
city: Le Cannet
country: France
facility: Research Site
state: Esterel
city: Nice
country: France
facility: Research Site
state: Esterel
city: St Laurent Du Var
country: France
facility: Research Site
state: Esterel
city: Lille Cedex
country: France
facility: Research Site
state: Flandres
city: Tourcoing
country: France
facility: Research Site
state: Flandres
city: Douelle
country: France
facility: Research Site
state: Gascogne
city: Lamagistere
country: France
facility: Research Site
state: Gascogne
city: Montauban
country: France
facility: Research Site
state: Gascogne
city: Villeneuve Sur Lot Cedex
country: France
facility: Research Site
state: Gascogne
city: Bois Guillaume
country: France
facility: Research Site
state: Haute Normandie
city: Pont de L Arche
country: France
facility: Research Site
state: Haute Normandie
city: Rouen
country: France
facility: Research Site
state: Haute Normandie
city: St Saens
country: France
facility: Research Site
state: Haute Normandie
city: Vernon Cedex
country: France
facility: Research Site
state: Haute Normandie
city: Cachan
country: France
facility: Research Site
state: Hauts de Seine
city: Le Kremlin Bicetre Cedex
country: France
facility: Research Site
state: Hauts de Seine
city: Neuilly Sur Seine
country: France
facility: Research Site
state: Hauts de Seine
city: Paris Cedex 12
country: France
facility: Research Site
state: Hauts de Seine
city: Paris
country: France
facility: Research Site
state: Hauts de Seine
city: Arles Cedex
country: France
facility: Research Site
state: Languedoc
city: Capdenac Gare
country: France
facility: Research Site
state: Languedoc
city: Castelnau Le Lez
country: France
facility: Research Site
state: Languedoc
city: Montpellier
country: France
facility: Research Site
state: Languedoc
city: Rieupeyroux
country: France
facility: Research Site
state: Languedoc
city: Villefranche de Rouergue C
country: France
facility: Research Site
state: Languedoc
city: Ahun
country: France
facility: Research Site
state: Limousin
city: Bourges
country: France
facility: Research Site
state: Limousin
city: Brive La Gaillarde
country: France
facility: Research Site
state: Limousin
city: Bruere Allichamps
country: France
facility: Research Site
state: Limousin
city: Chateauroux
country: France
facility: Research Site
state: Limousin
city: Limoges Cedex 1
country: France
facility: Research Site
state: Limousin
city: Rosiers D Egletons
country: France
facility: Research Site
state: Limousin
city: St Yrieix La Perche
country: France
facility: Research Site
state: Limousin
city: Forbach
country: France
facility: Research Site
state: Lorraine
city: Metz
country: France
facility: Research Site
state: Lorraine
city: Nancy
country: France
facility: Research Site
state: Lorraine
city: Thionville
country: France
facility: Research Site
state: Lorraine
city: Tonnoy
country: France
facility: Research Site
state: Lorraine
city: Toul Cedex
country: France
facility: Research Site
state: Lorraine
city: Vandoeuvre Les Nancy
country: France
facility: Research Site
state: Lorraine
city: Bron
country: France
facility: Research Site
state: Lyonnais
city: Francheville
country: France
facility: Research Site
state: Lyonnais
city: Gleize
country: France
facility: Research Site
state: Lyonnais
city: Lyon Cedex 02
country: France
facility: Research Site
state: Lyonnais
city: Lyon
country: France
facility: Research Site
state: Lyonnais
city: Pont Eveque
country: France
facility: Research Site
state: Lyonnais
city: Ajaccio
country: France
facility: Research Site
state: Maures Corse
city: Bormes Les Mimosas
country: France
facility: Research Site
state: Maures Corse
city: Furiani
country: France
facility: Research Site
state: Maures Corse
city: Six Fours Les Plages
country: France
facility: Research Site
state: Maures Corse
city: St Cyr Sur Mer
country: France
facility: Research Site
state: Maures Corse
city: Toulon
country: France
facility: Research Site
state: Maures Corse
city: Albi
country: France
facility: Research Site
state: Midi Pyrenees
city: Blagnac
country: France
facility: Research Site
state: Midi Pyrenees
city: Castanet Tolosan
country: France
facility: Research Site
state: Midi Pyrenees
city: La Tour Du Crieu
country: France
facility: Research Site
state: Midi Pyrenees
city: Lacrouzette
country: France
facility: Research Site
state: Midi Pyrenees
city: Plaisance Du Touch
country: France
facility: Research Site
state: Midi Pyrenees
city: Toulouse Cedex 9
country: France
facility: Research Site
state: Midi Pyrenees
city: Toulouse
country: France
facility: Research Site
state: Midi Pyrenees
city: Villeneuve Tolosane
country: France
facility: Research Site
state: Midi Pyrenees
city: Paris Cedex 14
country: France
facility: Research Site
state: Paris Centre
city: Champs Sur Marne
country: France
facility: Research Site
state: Paris Nord Est
city: Gagny
country: France
facility: Research Site
state: Paris Nord Est
city: Le Bourget
country: France
facility: Research Site
state: Paris Nord Est
city: Lognes
country: France
facility: Research Site
state: Paris Nord Est
city: Montfermeil
country: France
facility: Research Site
state: Paris Nord Est
city: Angers
country: France
facility: Research Site
state: Pays de Loire
city: Carquefou
country: France
facility: Research Site
state: Pays de Loire
city: Champigne
country: France
facility: Research Site
state: Pays de Loire
city: Cholet
country: France
facility: Research Site
state: Pays de Loire
city: Nantes
country: France
facility: Research Site
state: Pays de Loire
city: St Laurent de La Plaine
country: France
facility: Research Site
state: Pays de Loire
city: St Lyphard
country: France
facility: Research Site
state: Pays de Loire
city: St Nazaire
country: France
facility: Research Site
state: Pays de Loire
city: Thouare Sur Loire
country: France
facility: Research Site
state: Pays de Loire
city: Amiens
country: France
facility: Research Site
state: Picardie
city: Le Quesnoy
country: France
facility: Research Site
state: Picardie
city: St Quentin
country: France
facility: Research Site
state: Picardie
city: Wallers
country: France
facility: Research Site
state: Picardie
city: Marignane
country: France
facility: Research Site
state: Provence
city: Marseille
country: France
facility: Research Site
state: Provence
city: Miramas
country: France
facility: Research Site
state: Provence
city: Fleury Les Aubrais
country: France
facility: Research Site
state: Sologne
city: Montigny Sur Loing
country: France
facility: Research Site
state: Sologne
city: Orleans
country: France
facility: Research Site
state: Sologne
city: Vennecy
country: France
facility: Research Site
state: Sologne
city: La Riche
country: France
facility: Research Site
state: Touraine
city: Limeray
country: France
facility: Research Site
state: Touraine
city: Tours
country: France
facility: Research Site
state: Touraine
city: Dieulefit
country: France
facility: Research Site
state: Vallee Du Rhone
city: Noves
country: France
facility: Research Site
state: Vallee Du Rhone
city: Taillades
country: France
facility: Research Site
state: Vallee Du Rhone
city: Beauvais Cedex
country: France
facility: Research Site
state: Vexin
city: Cergy
country: France
facility: Research Site
state: Vexin
city: Gonesse Cedex
country: France
facility: Research Site
state: Vexin
city: St Just En Chaussee
country: France
facility: Research Site
state: Vexin
city: Vaureal
country: France
facility: Research Site
state: Vexin
city: Argenteuil Cedex
country: France
facility: Research Site
state: Yvelines
city: Elancourt
country: France
facility: Research Site
state: Yvelines
city: Le Chesnay Cedex
country: France
facility: Research Site
state: Yvelines
city: Le Chesnay
country: France
facility: Research Site
state: Yvelines
Study officials:
affiliation: KAPPA SANTE - Paris - France
name: Stephane SCHÜCK, MD, MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: CHU Bichat - Service de pneumologie - Paris - France
name: Michel AUBIER, MD, Professor
role: STUDY_CHAIR
References: