Clinical trial NCT05860725: Feasibility Trial of a Multi-level Media Production and Social Marketing Campaign to Reduce HPV Vaccine Hesitancy
Official title: Appalachian Voices for Health - Feasibility Trial of a Multi-level Media Production and Social Marketing Campaign to Reduce HPV Vaccine Hesitancy
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Human Papillomavirus Infection
Vaccination Hesitancy
Lead sponsor: University of Virginia
Sponsor class: OTHER
First posted: 2023-05-16
Enrollment: 220
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Since 2019, the HPV working group of the University of Virginia Cancer Center's Southwest Virginia Community Advisory Board has developed and executed strategies to increase regional HPV vaccination rates. Members collaboratively developed Appalachian Voices for Health, a multi-level media production and social marketing intervention. This novel intervention builds on the past efforts of the working group and the engaged organizations; takes into account the impact of vaccine hesitancy on HPV vaccination uptake; and incorporates best practices. Through the intervention, Nursing and Dental Assistant students from Mountain Empire Community College will develop PSAs after receiving training about HPV vaccination and health communication. These PSAs will be used in a social marketing campaign executed through a regional transportation system managed by Mountain Empire Older Citizens. Specifically, the trial's aims are three-fold: assess the intervention's impact on community members' and students' HPV vaccine hesitancy (Aim 1) and perceptions and actions related to HPV vaccination (Aim 2) and evaluate other feasibility indicators at the community-, student-, organizational-, and process levels (Aim 3). The research team will use a concurrent mix-methods approach to assess feasibility indicators. Aims will be assessed using surveys, focus groups, meeting minutes, and implementation records. Data will be analyzed using descriptive and inferential statistics and content coding. Determination of the intervention's feasibility will consider the achievement benchmarks for feasibility indicators individually and collectively. Data will be used to inform refinement and future testing of Appalachian Voices for Health.


Eligibility criteria: Inclusion Criteria:

* Age 18 or older
* enrolled as a student in one of the regional community college's health sciences programs (Phase 1 only)
* ride the regional health services focused non-profit's rideshare buses or view their social media during one or more of the three survey periods (Phase 2 only)
* work for either the regional community college or non-profit AND were involved in supporting the execution of the study components within their organization.

Exclusion Criteria:

* Under 18

Primary outcomes:
measure: Vaccination hesitancy scale modified for the HPV vaccine (VHS-HPV)
timeFrame: Change in community members' self-reported VHS-HPV score pre-post intervention (14 week period / Phase 2)
measure: Vaccination hesitancy scale modified for the HPV vaccine (VHS-HPV)
timeFrame: Change in Health Sciences students' self-reported VHS-HPV score pre-post intervention (6 week period / Phase 1)
Secondary outcomes:
measure: Vaccination hesitancy scale (VHS)
timeFrame: Change in community members' self-reported VHS score pre-post intervention (14 week period / Phase 2)
measure: Vaccination hesitancy scale (VHS)
timeFrame: Change in Health Science students' self-reported VHS score pre-post intervention (6 week period / Phase 1)
Other outcomes:
Locations:
city: Charlottesville
country: United States
facility: University of Virginia
state: Virginia
Study officials:
References: