louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT02290730: Effect of Kinesio Taping on Muscle Strength in Lower Trapezius
Official title: The Effect of One Application of Kinesio Tape on Muscle Strength in Lower Trapezius on Patients With Shoulder Problems and Weak Lower Trapezius - a Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Shoulder Pain
Muscle Weakness
Keywords: Lower trapezius
Kinesio taping
Lead sponsor: Norwegian School of Sport Sciences
Sponsor class: OTHER
First posted: 2014-11-14
Enrollment: 49
Sex: ALL
Minimum age (years): 18
Maximum age (years): 67
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this project is to investigate the effect of Kinesio tape on muscle strength of the lower trapezius in people with shoulder symptoms and decreased muscle strength in the lower trapezius - a randomized controlled trial.

Detailed description: The aim of the study is to investigate the effect of recoil tape with 0-30% tension, by using one application of Kinesio tape over the muscle fibers of the lower trapezius from its origin to its insertion. The participants will be divided into intervention group (taping) and control group (no intervention). Muscle strength test will be performed before and immediately after taping (20-30 minutes) for both groups using hand-held dynamometer measurements (MicroFET 3).

Work is based on the following hypothesis: "Kinesio taping using recoil taping provides increased isometric muscle strength in lower trapezius immediately after application".

Eligibility criteria: Inclusion Criteria:

* Shoulder problems
* Low muscle strength in lower trapezius
* Positive manual recoil-test for the lower trapezius

Exclusion Criteria:

* Shoulder surgery \<3 month
* Pathology in the shoulder related to tumors, fractures, neurology, rupture of tendons

Primary outcomes:
measure: Muscle strength
timeFrame: 30 minutes
Secondary outcomes:
measure: Time of break force
timeFrame: 30 minutes
measure: Self-reported strength - effort scale
timeFrame: 30 minutes
Other outcomes:
Locations:
city: Oslo
country: Norway
facility: Norwegian School of Sport Sciences
Study officials:
affiliation: Department of Sports Medicine
name: Grethe Myklebust, Phd, PT
role: STUDY_DIRECTOR
References:
Clinical trial NCT06440330: Define Predictors for Posttransplant Diabetes Mellitus Study
Official title: Define Predictors for Posttransplant Diabetes Mellitus Study
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Post-transplant Diabetes Mellitus
Kidney Transplant; Complications
Lead sponsor: University Hospital, Antwerp
Sponsor class: OTHER
Collaborators: name: Universitair Ziekenhuis Brussel
name: University Ghent
name: Universitaire Ziekenhuizen KU Leuven
name: HUB
name: Université Catholique de Louvain
name: Centre Hospitalier Universitaire de Liege
First posted: 2024-06-03
Enrollment: 330
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Kidney transplant recipients without known pre-existing diabetes.

Brief summary: The primary aim of this prospective, multicentre study is to develop an accurate and convenient tool to predict the risk of PTDM at 3 months post-transplant, based on information on the day of transplantation (day 0).

In order to create such model, we will start by identifying individual predictor variables at the day of transplantation and subsequently explore the optimal combination of these predictors in multivariable models.

Secondary objectives include:

* Compare the performance of the model based on predictor variables at day 0 with existing models for prediction of PTDM (Chakkera, San Antonio Diabetes Prediction Model and Framingham Offspring Study Diabetes Mellitus algorithm)
* Explore the glucose level evolution during the first 2 weeks after transplantation using continuous glucose monitoring, and its relationship with baseline patient characteristics and immunosuppressant drug use.
* Evaluate the added value of incorporating information on glucose levels in the first and second weeks post-transplant to improve the PTDM prediction model.
* Identify predictors for early post-transplant hyperglycemia (first 2 weeks post-transplantation)
* Explore the correlation between early post-transplant hyperglycemia (fasting glycemia, pre-dinner glycemia) and PTDM at 3 months


Eligibility criteria: Inclusion Criteria:

* Adult patients (≥18 years) with end stage kidney disease undergoing kidney transplantation with a deceased or living donor
* Signed informed consent
* Initial therapy with at least tacrolimus and corticosteroids

Exclusion Criteria:

* Patients with a diagnosis of diabetes mellitus (either type 1 or type 2) prior to kidney transplantation
* Treatment with GLP1-RA for weight losing purposes
* Patients receiving a multi-organ transplantation
* ABO incompatibility

Primary outcomes:
measure: Post-transplant diabetes mellitus
timeFrame: at 10-13 weeks post-transplantation
Secondary outcomes:
Other outcomes:
Locations:
city: Edegem
country: Belgium
facility: UZA
state: Antwerpen
Study officials:
References:
Clinical trial NCT00973830: The Missouri Health Literacy and Diabetes Communication Initiative
Official title: The Missouri Health Literacy and Diabetes Communication Initiative
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Diabetes Knowledge
Keywords: Changes in HbA1c
Lead sponsor: Northwestern University
Sponsor class: OTHER
First posted: 2009-09-09
Enrollment: 667
Sex: ALL
Minimum age (years): 25
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: Objective: to evaluate the efficacy of the American College of Physicians Foundation (ACPF) Diabetes Guide (Living with Diabetes: An Everyday Guide for You and Your Family) to improve diabetes self-management.

Study Sites: Nine Federally-qualified health centers or safety-net clinics at three sites in Missouri. Sites are urban (St. Louis), midsize (Columbia) and rural (Kirksville). Three FQHCs or safety net clinics are located at each of the sites.

Methods Overview and Design: A randomized controlled trial will be conducted. Patients will be recruited from identified health centers. As the intervention itself is directed to the clinic and not patient, the clinics will be randomly assigned to either 1) usual care (no treatment), 2) "Carve-In" - patients receive the Diabetes Guide and clinic staff follow-up and work with patients to create and complete action plans or 3)"Carve-Out" - patients receive the Diabetes Guide and a diabetes educator in Chicago follows up and works with patients to create and complete action plans. Recruited subjects will be administered a baseline assessment, and 3-month and 1-year follow-up assessments.

Sample: The investigators will recruit a total of 1,080 patients (n=120 per clinic) anticipating 80 percent retention through both follow-up assessments (final estimated number of patients = 720). Eligibility to participate will be defined as patients 1) ages 30 and older (to better represent disease distribution), 2) English or Spanish-speaking, 3) a confirmed (by chart) diagnosis of uncontrolled diabetes (HBA1c 7.0 or more).


Eligibility criteria: Inclusion Criteria:

* Uncontrolled diabetes patients (defined as HbA1c 6.0 or greater).
* 25 years or older
* English or Spanish speaking

Exclusion Criteria:

* Uncorrectable hearing or visual impairment
* Moderate to severe cognitive deficits

Primary outcomes:
measure: Diabetes knowledge
timeFrame: 3 months, 1 year
Secondary outcomes:
measure: Change in HbA1c reading
timeFrame: 3 months, 1 year
Other outcomes:
Locations:
city: Chicago
country: United States
facility: Northwestern University
state: Illinois
Study officials:
affiliation: Northwestern University
name: Michael S. Wolf, PhD, MPH
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01895530: Impact of Probiotics in Modulation of Intestinal Microbiota
Official title: Impact of Probiotics in Modulation of Intestinal Microbiota of Patients Undergoing a Resection Colonic
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Colorectal Cancer
Keywords: Probiotics
colorectal cancer
postoperative infection
immune function
bacterial translocation
gastrointestinal surgery
Lead sponsor: Federal University of Minas Gerais
Sponsor class: OTHER
First posted: 2013-07-10
Enrollment: 33
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The investigators would study about impact of the administration of probiotics in the intestinal mucosa of patients undergoing resection colic, by evaluating cytokine profile by quantitative real time PCR. The investigators believe that patients who use probiotic preoperative would provide cytokine profile less inflammatory than those of the control group.

Detailed description: Samples of colorectal cancer-free mucosa derived from patients who underwent surgical resection were investigated. Quantitative real-time polymerase chain reaction (RT-qPCR) was used to determine expression levels of the following genes: IL10, IL1B, IL23A, TNF, IL12B, INFG, IL17A.

Eligibility criteria: Inclusion Criteria:

* if he or she were older than 18 years
* intended to undergo elective CRC resection at UFMG Hospital

Exclusion Criteria:

* Patients were excluded if they were not able to receive the probiotics seven days before the operation
* if colon resection was not performed due to changes in operation strategy, or if they discontinued probiotic use on their own or
* if they removed their consent.

Primary outcomes:
measure: Difference in gene expression of citokynes
timeFrame: 15 days
Secondary outcomes:
measure: Postoperative complications
timeFrame: 30 days
Other outcomes:
Locations:
city: Belo horizonte
country: Brazil
facility: UFMG Hospital
state: Minas Gerais
Study officials:
affiliation: Federal University of Minas Gerais
name: Isabel TD Correia, PhD
role: STUDY_DIRECTOR
References:
Clinical trial NCT04927130: Retrospective Comparative in Vitro Case-controlled Study of the Liquid Biopsy Test System in Women With Breast Cancer
Official title: An International Multicenter Blind Retrospective Comparative in Vitro Case-controlled Study of the ARNA Breast Liquid Biopsy Test System in Women With Biopsy Confirmed Breast Cancer
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Breast Neoplasm Female
Lead sponsor: ARNA Genomics US Inc.
Sponsor class: INDUSTRY
Collaborators: name: BIOMARKER-RU
First posted: 2021-06-15
Enrollment: 150
Sex: FEMALE
Minimum age (years): 35
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Women of the required age group, in case of breast cancer has been confirmed but not treated, are sent to donate blood samples.

Brief summary: Proof of Concept retrospective study. Women who have the diagnosis Breast Cancer ( confirmed by biopsy) will donate a blood samples. Tubes with blood will be transferred to the Sponsors Laboratory and ARNA Breast Test will be performed. The result of test will be compared with the biopsy result for each person.


Eligibility criteria: Inclusion Criteria:

* Availability of signed and dated informed consent.
* Women from 35 to 65 years old, who are generally healthy, with confirmed breast cancer. Or without any neoplasms in breast (control group)
* Presence of a documented biopsy
* Presence of mammography, ultrasound or MRI of the mammary glands no later than three months.

Exclusion Criteria:

* Pregnancy.
* Any other cancers diagnosed now or previously, with the exception of breast cancer.
* Therapy with cytostatic during the last three months.
* Chemotherapy within the past three months.
* Therapy with hormonal drugs, including all forms of contraceptive drugs.
* Therapy with other prohibited groups of drugs.
* Systolic blood pressure \> 180 mm Hg. and / or diastolic blood pressure \> 120 mm Hg. with repeated measurements.
* Simultaneous participation in another clinical study.
* Relative affiliation to the clinic, for example, the patient is a close relative of the researcher or a dependent person (for example, a clinic employee or student or a sponsor employee).
* A clinically significant condition or laboratory result that, in the opinion of the investigator, threatens the safety of the test subject, may interfere with assessments, or prevent the completion of the study.
* Failure to cooperate to participate in planned procedures, including the following examples: lack of understanding of language, mental illness, inability to visit the clinic.
* Diseases or conditions that may affect the conduct of the study or the interpretation of the results.
* History of organ transplantation.
* Blood transfusions within the last 6 months.

Primary outcomes:
measure: The number of true positive cases
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Moscow
country: Russian Federation
facility: K+31
Study officials:
References:
Clinical trial NCT03706430: Validation of RPVi as a Parameter to Predict Fluid Responsiveness
Official title: Validation of RPVi as a Parameter to Predict Fluid Responsiveness
Study type: INTERVENTIONAL
Overall status: TERMINATED
Conditions: Surgery
Anesthesia
Lead sponsor: Masimo Corporation
Sponsor class: INDUSTRY
First posted: 2018-10-16
Enrollment: 63
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SEQUENTIAL
Primary purpose: OTHER

Brief summary: This is a prospective, nonrandomized, sequential data collection study to evaluate the ability of RPVi to predict fluid responsiveness in comparison with other dynamic parameters including stroke volume variation (SVV) and/or pulse pressure variation (PPV).


Eligibility criteria: Inclusion Criteria:

* 18 years of age or older at the time of consent
* Scheduled for elective surgery requiring general anesthesia and mechanical ventilation
* Arterial line and other standard of care line placement indicated as part of the scheduled surgical procedure

Exclusion Criteria:

* Patients diagnosed with or history of heart failure, angina, pulmonary heart disease, rheumatic heart disease, cardiomyopathy, congenital heart disease, or valvular heart disease.
* Patients scheduled for or has had a liver transplant
* Patients with surgeries at or around site of sensor placement or skin abnormalities affecting the sensor placement area such as psoriasis, eczema, angioma, scar tissue, burn, fungal infection, substantial skin breakdown, nail polish or acrylic nails that would prevent monitoring of pulse-oximeter physiological parameters during the study.
* Patients with cardiac arrhythmias
* Patients with intracardiac shunts

Primary outcomes:
measure: Comparison of RPVi to SVV and/or PPV
timeFrame: approximately 2-6 hours during surgery
Secondary outcomes:
Other outcomes:
Locations:
city: Los Angeles
country: United States
facility: University of California, Los Angeles
state: California
Study officials:
References:
Clinical trial NCT06862830: The Effectiveness of Virtual Reality in the Management of Procedural Anxiety and Pain in Children Suffering From Chronic Pathologies or Burn Injuries.
Official title: The Effectiveness of Virtual Reality in the Management of Procedural Anxiety and Pain in Children Suffering From Chronic Pathologies or Burn Injuries. Single-center Randomized Controlled Trial.
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Anxiety
Chronic Disease
Pain
Keywords: Virtual Reality
Chronic pain
Paediatric
Chronic disease
Lead sponsor: Meyer Children's Hospital IRCCS
Sponsor class: OTHER
First posted: 2025-03-06
Enrollment: 260
Sex: ALL
Minimum age (years): 3
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Single-center, randomized, controlled clinical trial (RCT) to evaluate the efficacy of VR on pain and anxiety in children with chronic diseases undergoing painful procedures in an outpatient or day hospital setting


Eligibility criteria: Eligibility Criteria: Inclusion

The study population includes children who meet the following criteria:

1. Diagnosis of a chronic condition, aged 3 to 18 years, without visual impairments or cognitive deficits, and with a confirmed diagnosis of the condition.
2. Children receiving care in the wound care nursing clinic or Medical Day Hospital (DH) who require minimally invasive painful procedures.
3. Assent and informed consent provided by both the children and their parents.
4. Children with chronic conditions that do not inherently cause chronic pain, which could alter pain perception (e.g., rheumatoid arthritis, diabetic foot, muscular dystrophy).
5. Children able to understand and communicate in Italian or English.
6. Parents able to understand and communicate in Italian or English. Eligibility Criteria: Exclusion

Children with the following characteristics will be excluded from the study:

1. Chronic condition not yet diagnosed.
2. Use of eyeglasses, presence of amblyopia or monocular vision.
3. Chronic pain, which could distort pain perception during the procedure.
4. Use of analgesic therapy within the last 8 hours, which could bias data collection results (the only prohibited therapy in the study and a reason for exclusion).
5. Cognitive impairment preventing the proper use of assessment scales.

Primary outcomes:
measure: Percentage reduction in anxiety score
timeFrame: From recruitment to end of painful procedure
measure: Percentage reduction in pain
timeFrame: From recruitment to end of painful procedure
Secondary outcomes:
measure: Percentage of reduction in parental anxiety
timeFrame: From recruitment to end of painful procedure
Other outcomes:
Locations:
city: Florence
country: Italy
facility: Meyer Children's Hospital IRCCS
Study officials:
References:
Clinical trial NCT03728530: Effect Of Deep Breathing Exercises In Smokers
Official title: Effect Of Deep Breathing Exercises In Smokers
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy Smokers
Keywords: Deep breathing exercises, smokers, lung function
Lead sponsor: Isra University
Sponsor class: OTHER
First posted: 2018-11-02
Enrollment: 30
Sex: ALL
Minimum age (years): 20
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Study was to determine the effects of deep breathing exercises in smokers. It was conducted on the general population of Isra Institute of Rehabilitation Sciences, Isra University, Islamabad Campus. 30 participants were selected through Non probability Convenience Sampling and later equally divided into experimental (n=15) and control group (n=15) through lottery method. Inclusion criteria were young smokers between 20-30 years of age and without any chronic pulmonary complication, smoking for past five years. Smokers with any pulmonary disease, acute infections, other systemic disease, chest deformity or any disability were excluded from study.
Primary purpose: PREVENTION

Brief summary: To determine the effect of deep breathing exercises on lung function in healthy smokers.

Detailed description: The purpose of the study to determine the effect of deep breathing exercise in smokers because deep breathing improve the lung capacity by filling the lung with the oxygen and improve the pulmonary function, it also reduce the stress and anxiety level by slowing down the pace of your whole body and therefore promote general relaxation and improve the quality of life in smokers, muscular activity or physical activity is also increased because by deep breathing maximum oxygen is reached to every muscle and they get nourish well so overall impact of deep breathing exercise is positive. Deep breathing exercise technique offered in the study are easy to learn and can be performed by everyone and everywhere safely, because there is no complex and pain full procedure. So deep breathing exercise have been proposed as a way of combating cigarette craving, improves quality of life and lung function.

Eligibility criteria: Inclusion Criteria:

Young male and female adults with age group of 20-30 years without any chronic complication doing smoking from past five years are included in this study as the basic purpose of the study is to determine the effects of deep breathing exercises in smokers

Exclusion Criteria:

1. Adults with pulmonary disease.
2. Acute infections
3. Any other systemic disease.
4. Chest deformity.
5. Adults with any disability.

Primary outcomes:
measure: Oxygen Saturation
timeFrame: 2 weeks
measure: Lung Volumes
timeFrame: 2 weeks
measure: Lung Capacities
timeFrame: 2 weeks
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT06565130: Wheelchair Basketball and Attention Training
Official title: Attention Skills of Wheelchair Basketball Players: Occupational Therapy Intervention
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Physical Disability
Keywords: attention skills
occupational therapy
wheelchair basketball
Lead sponsor: Bezmialem Vakif University
Sponsor class: OTHER
First posted: 2024-08-21
Enrollment: 9
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: The goal of this interventional study is to evaluate the effect of attention training on performance in wheelchair basketball players. The main question it aims to answer is:

Does attention training have an effect on the performance of wheelchair basketball players? Participants will participate attention training from an occupational therapy perspective.

Detailed description: The attention skills of the athletes will be evaluated with a competition-like designed assessment session. Then, the planned 10-week intervention program will be carried out as one session per week. After the intervention program, the evaluation session will be repeated and the results will be recorded. Then, it will be evaluated whether there is improvement in the attention skills of the athletes. The results obtained will be important for athletes, coaches and professionals working in this field.

Eligibility criteria: Inclusion Criteria:

* Actively active in a regional wheelchair basketball team for at least 6 months.
* Volunteering to participate in the research.
* Being literate.

Exclusion Criteria:

* Having a neurological or cognitive disorder other than a physical disability.
* Being colorblind.

Primary outcomes:
measure: The number of successful shots
timeFrame: 10 week
Secondary outcomes:
measure: The time to complete the track and each stage
timeFrame: 10 week
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakif University
Study officials:
References: