Clinical trial NCT01055730: The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease
Official title: The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease: A Prospective Cohort Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Interstitial Lung Disease
Keywords: Pulmonary rehabilitation
Exercise therapy
Interstitial lung disease
Pulmonary fibrosis
Mobility limitation
Dyspnea
Mental health
Lead sponsor: University of California, San Francisco
Sponsor class: OTHER
First posted: 2010-01-26
Enrollment: 54
Sex: ALL
Minimum age (years): 19
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Any patient with interstitial lung disease who is referred to a participating pulmonary rehabilitation program. These patients typically have exercise limitation and dyspnea, but still possess the ability to perform some exercise.

Brief summary: The purpose of this study is to determine if pulmonary rehabilitation has any effect on breathlessness, quality of life, physical function and depression in persons with interstitial lung disease.


Eligibility criteria: Inclusion Criteria:

* Adults (\> 18 years old) with a diagnosis of ILD who are referred to a participating PR program

Exclusion Criteria:

* Inability to provide informed consent
* Inability to read and write English
* Any other medical condition that significantly limits the subject's ability to perform the functional measures
* Emphysema / Chronic bronchitis (FEV1 / FVC ratio \< 60%)
* Previous pulmonary rehabilitation

Primary outcomes:
measure: 6-minute walk distance
timeFrame: Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation
measure: Quality of life
timeFrame: Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation
Secondary outcomes:
measure: Dyspnea
timeFrame: Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation
measure: Depression
timeFrame: Immediately following completion of pulmonary rehabilitation and 6 months following the start of pulmonary rehabilitation
Other outcomes:
Locations:
city: Concord
country: United States
facility: John Muir Health
state: California
city: Daly City
country: United States
facility: Seton Pulmonary & Cardiac Rehabilitation
state: California
city: New Haven
country: United States
facility: Yale University School of Medicine
state: Connecticut
city: Durham
country: United States
facility: Duke University Medical Center
state: North Carolina
city: Falls Church
country: United States
facility: Inova Fairfax Hospital
state: Virginia
city: Vancouver
country: Canada
facility: University of British Columbia
state: British Columbia
Study officials:
affiliation: University of California, San Francisco
name: Harold R Collard, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: University of California, San Francisco
name: Christopher J Ryerson, MD
role: PRINCIPAL_INVESTIGATOR
affiliation: Seton Pulmonary & Cardiac Rehabilitation
name: Chris Garvey, FNP
role: PRINCIPAL_INVESTIGATOR
References:
citation: Ryerson CJ, Cayou C, Topp F, Hilling L, Camp PG, Wilcox PG, Khalil N, Collard HR, Garvey C. Pulmonary rehabilitation improves long-term outcomes in interstitial lung disease: a prospective cohort study. Respir Med. 2014 Jan;108(1):203-10. doi: 10.1016/j.rmed.2013.11.016. Epub 2013 Dec 4.