Clinical trial NCT06224465: Effect of Anti-aging Therapy on Fitness Enhancement in Perimenopausal Women
Official title: Effect of Anti-aging Therapy on Fitness Enhancement in Perimenopausal Women
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Aging Well
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2024-01-25
Enrollment: 40
Sex: FEMALE
Minimum age (years): 40
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: intervention: aerobic exercises: walking :30 min on treadmill 30min at least three times per week for 12 weeks 2)Muscle strength Exercises: For upper extremity : hand grip exercise, arm flexion exercise ten repetition for each exercise three times per week.

Theraband exercises for upper limb exercise ten repetition for each exercise three times per week.

3) Flexibility Exercise : Curl up exercise and Seat and reach up exercises exercise ten repetition for each exercise three times per week.

Lateral flexibility exercises for ten repetition for each exercise three times per week,for 12 weeks
Primary purpose: TREATMENT

Brief summary: Aging is an important fact to consider from the woman's health perspective. One of the most significant stages of aging is menopause, in which involves physical, psychological, and social changes in life

Detailed description: This study will be carried on forty perimenopausal women. They were selected randomly from outpatient clinic of El Kaser El-Einy University Hospital, Cairo University, their age ranged from 40 to 50 years.

Group A ( Control group):

It consisted of 20 perimenopausal women. They received anti-aging diet instructions.

Group B ( Experimental group):

It will be consisted of 20 perimenopausal women.They received anti-aging therapy (Aerobic, Flexibility and strengthening exercises) with anti aging diet instructions.

Randomization:

Randomization of sample selection was achieved using closed envelop way. Classification of the sample by simple random way into two groups equal in number, twenty for each group by using forty closed envelop, each twenty envelop contained a name of a group from the two groups (Group A) or (Group B) and asking each woman to choose one envelop from them, each woman attended to the group according the name of the group written in her envelop.

Eligibility criteria: Inclusion Criteria:

* They complaining from fatigue, hot flushes and irregular period.
* Their Body Mass Index (BMI) between 25 to 30 .
* Their age ranged from 40 to 50 years old.
* The assessment procedures will be conducted on the same time of the day pre/post treatment.

Exclusion Criteria:

* Women with comorbidities such as cardiac disease and chest diseases as pulmonary fibrosis.
* Women received medications that might affect the neuromuscular functions at least three months before or during the study course.
* Women suffered from mental or psychological disorders.
* Women suffered from inflammatory diseases such as rheumatoid arthritis or polymyalgia rheumatic.
* Women complaining from osteoporosis.

Primary outcomes:
measure: 6-minute walking test
timeFrame: 12 weeks
measure: toe touch test
timeFrame: 12 weeks
measure: hand held dynamometer
timeFrame: 12 weeks
measure: body composition analysis
timeFrame: 12 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: faculty of physical therapy, Cairo University
Study officials:
affiliation: Cairo University
name: Amel Yousef
role: STUDY_CHAIR
References: