Clinical trial NCT02228694: The IMPROVE Study-IMPact of a Regulated ADC System
Official title: IMPact of a Regulated ADC System On Medication Distribution and Administration VariablEs
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Medication Administered in Error
Medication Compliance
Keywords: ADC
Pre installation
Post installation
Safety
Time
Lead sponsor: Hackensack Meridian Health
Sponsor class: OTHER
Collaborators: name: Omnicell
First posted: 2014-08-29
Enrollment: 120
Sex: ALL
Minimum age (years): 22
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Number of Participants by Group

* Children (Minor Subjects): 0
* Cognitively Impaired Participants:0
* Employees and Students: 120
* Patients: 25238
* Prisoners: 0
* Normal Healthy Volunteers: 0
* Pregnant Women-Human Fetuses: 0
* Wards: 0

Brief summary: An automated dispensing cabinet (ADC) is a computerized drug storage device or cabinet designed for hospitals. ADCs allow medications to be stored and dispensed near the point of care while controlling and tracking drug distribution.This study seeks to obtain quantitative measurements of the impact of the regulated ADC System installed in select high volume units throughout the hospital.

Detailed description: The goal of this study is to evaluate the impact of the regulated ADC Systems on the medication administration processes. HackensackUMC is specifically interested in measuring the time to first dose administration from scheduled dosing times of the IV antibiotic piperacillin and tazobactam for injection, USP. and we are interested in assessing a reduction in time from scheduled dosage times of first dose to documented administration after the implementation of the regulated ADC system compared to before.

Timely administration of antibiotics improves morbidity, mortality, and length of hospital stay.Early and effective antibiotic therapy is essential in the management of infection in critical illness. The loading dose is probably the most important dose and is a function of the volume of distribution of the drug and the desired plasma concentration but independent of renal function.

Eligibility criteria: Inclusion Criteria:

* Subjects treated at study site in units where regulated ADC System was installed where greater number of medications is administered due to patient volume per nurse assignment or where greater throughput occurs
* Time-sensitive scheduled medications administered on units where administration includes the use of the medication label printer
* Piperacillin and tazobactam for injection, USP (United States Pharmacopeia)
* All IV antibiotics
* Insulin
* Heparin

Exclusion Criteria:

* Medication administration data prior to January 1, 2013;
* Medication administration data after March 31, 2013 through December 31, 2013;
* Medication administration data after March 31, 2014.

Primary outcomes:
measure: Medication Administered in Error
timeFrame: six months
Secondary outcomes:
measure: Timeliness of medication administration
timeFrame: six months
Other outcomes:
Locations:
city: Hackensack
country: United States
facility: Hackensack University Medical center
state: New Jersey
Study officials:
affiliation: Hackensack Meridian Health
name: Claudia Douglas, DNP
role: PRINCIPAL_INVESTIGATOR
References: