Clinical trial NCT05617079: The State of Nebulizer Therapy in Russian Federation
Official title: The State of Nebulizer Therapy in Russian Federation: a National Survey Among Medicine Physicians
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Survey
Respiratory Failure
Respiratory Disease
Lead sponsor: Russian Federation of Anesthesiologists and Reanimatologists
Sponsor class: OTHER
First posted: 2022-11-15
Enrollment: 370
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Medicine physicians (VMP) practicing in the hospital and in the community settings.

Brief summary: It is known that the inhalation (nebulizer) use of drugs is of great importance in the intensive care of patients with acute and chronic respiratory failure of various origins.

Searching PubMed data for the last 5 years (2017-2022) for the keywords "nebulizer therapy" revealed 533 publications, and "mesh nebulizer therapy" - only 25 sources.

During the same period, the national database (E-Library) has 75 publications for the keywords "nebulizer therapy", and 4 sources for "mesh nebulizer therapy".

It should be noted that almost all publications are devoted to the use of nebulizers for specific diseases and pathological syndromes. There are no works evaluating the adherence of specialists, systemic indications and actually used methods.

The aim of trial is to study the current state of the use of nebulizer therapy in medical organizations and identify ways to improve its effectiveness This study is planned to be carried out using a questionnaire using a database based on the Internet electronic survey form.

Detailed description: We intend to involve at least 3 medical organizations in the subjects of the Russian Federation with a population of up to 1 million people; at least 5 medical organizations in the constituent entities of the Russian Federation with a population level of 1 to 3 million people, at least 7 organizations with a population level of more than 3 million people. In cities of the Russian Federation with a population of 1 million people or more - at least 5 medical organizations, and in the cities of Moscow and St. Petersburg - at least 10 medical organizations.

Eligibility criteria: Inclusion Criteria:

* Medical physicians

Exclusion Criteria:

* Lack of experience in conducting nebulizer therapy. Lack of technical capability for nebulizer therapy in a medical organization.

Primary outcomes:
measure: Structure of indications, methods and frequency of use of nebulizer therapy
timeFrame: up to 1 month after inclusion
Secondary outcomes:
measure: Drugs and frequency of their use during nebulizer therapy
timeFrame: up to 6 month after inclusion
measure: The frequency of use of nebulizer therapy for high-flow oxygen therapy, non-invasive ventilation and mechanical ventilation
timeFrame: up to 6 month after inclusion
Other outcomes:
Locations:
city: Krasnoyarsk
country: Russian Federation
facility: Alexey Gritsan
Study officials:
affiliation: Krasnoyarsk State Medical University n.a. prof. V.F. Voyno-Yasenetsky
name: Alexey Gritsan, MD
role: PRINCIPAL_INVESTIGATOR
References: