Clinical trial NCT04512391: Analgesic Efficacy of Erector Spinae Plane Block After Breast Cancer Surgery
Official title: Analgesic Efficacy of Erector Spinae Plane Block After Breast Cancer Surgery
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Postoperative Pain
Breast Cancer
Keywords: Erector spinae plane block
breast cancer
surgery
postoperative pain
analgesic
Lead sponsor: TC Erciyes University
Sponsor class: OTHER
First posted: 2020-08-13
Enrollment: 40
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: all patients undergoing breast surgery for breast cancer between September 2018 and December 2019 were included in our study.

Brief summary: Erector spinae plane block(ESPB), which is firstly used for thoracic neuropathic pain, is newly developed and highly promising fascial plane block for providing postoperative analgesia for a great deal of surgeries including breast surgery. The investigators aim to study efficacy of ESPB for patients who undergone breast cancer surgery and is expected to benefit from opioid-sparing effect of this technique.

Detailed description: This is a retrospective, single-center clinical trial to evaluate analgesic efficacy of Erector spinae plane block (ESPB) after breast cancer surgery. Participant's demographics and medical history, type and extent of surgery, systemic opioid and non-opioid analgesic consumptions, hemodynamic variables and adverse events during and first 24 hours after surgery. After operation, pain scores at first 24 hours, 1., 3., and 6. month will be obtanied from surgical ward and pain clinic registires. patient controlled analgesia device usage history will be obtained from device database at our clinic.

Eligibility criteria: Inclusion Criteria:

* ASA I-II patients undergoing breast surgery for breast cancer
* Becoming available of complete records about study data

Exclusion Criteria:

* ASA III-IV patients
* missing records about study data

Primary outcomes:
measure: Opioid Consumption
timeFrame: First 24 hours after surgery
measure: Verbal Analog Pain Scores on rest and movement
timeFrame: First 24 hours after surgery, at 1., 3., 6. month
Secondary outcomes:
measure: Demographic Data
timeFrame: First 24 hours after surgery
measure: Blood Pressures
timeFrame: during and first 24 hours after surgery
measure: Heart Rate
timeFrame: during and first 24 hours after surgery
measure: incidence of adverse effects (like nausea and vomiting)
timeFrame: First 24 hours after surgery
measure: Rescue analgesic requirement
timeFrame: First 24 hours after surgery
Other outcomes:
Locations:
city: Kayseri
country: Turkey
facility: TC erciyes university
state: Melikgazi
Study officials:
affiliation: Research Asisstant
name: ersin SÖNMEZ
role: PRINCIPAL_INVESTIGATOR
References:
citation: Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.
citation: Gurkan Y, Aksu C, Kus A, Yorukoglu UH, Kilic CT. Ultrasound guided erector spinae plane block reduces postoperative opioid consumption following breast surgery: A randomized controlled study. J Clin Anesth. 2018 Nov;50:65-68. doi: 10.1016/j.jclinane.2018.06.033. Epub 2018 Jul 2.