Clinical trial NCT04994925: Ready Meal Consumption, Appetite and Food Intake in Females
Official title: The Effects of Ready Meal Consumption on Self-reported Appetite Ratings and Subsequent Food Intake in Females
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Overweight
Lead sponsor: Oxford Brookes University
Sponsor class: OTHER
First posted: 2021-08-06
Enrollment: 26
Sex: FEMALE
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: Overweight and obesity are public health concerns and there is a forecast rise in the consumption of ready meals that are generally high in saturated fat and low in fibre. Slimming World, a commercial weight management organisation has designed a range of ready meals in line with their weight management programme, which advocates an unrestricted intake of low energy dense food in order to aid in weight loss. Hence, it is valuable to understand the satiating properties of ready meals in order to establish if specific ready meals can enhance satiety and contribute to reducing subsequent energy intake. This study aims to explore the effect of ready meals on short-term satiety and food intake among females with a BMI ≥ 25 kg/m2.

Detailed description: A total of 26 female participants aged between 18-65 years attended Oxford Brookes Centre for Nutrition and Health for two separate testing days. The study aimed to investigate the effects of energy matched ready meals (calorie-matched but differing quantities of protein and fat) on appetite and subsequent energy and macronutrient intake. The ready meals (Control = supermarket brand and Test = Slimming World) differed in energy density and macronutrient composition, with satiety responses investigated in the studies. The participants consumed a standard breakfast and four hours later consumed either a test ready meal (lasagne, higher energy density) or the control ready meal (lower energy density). Four hours after lunch participants food intake was measured during an ad libitum buffet tea. Additionally, satiety measurements were recorded using visual analogue scales throughout and participants completed a weighed food diary for the remainder of the test day.

Eligibility criteria: Inclusion Criteria:

* healthy, non-smoking females aged between 18-65 years with a BMI ≥ 25 kg/m2.

  * had no known food allergies to the study foods,
  * had no eating disorders,
  * were not following a special diet (e.g. vegetarian, halal),
  * were not taking any medication or supplements known to affect appetite or weight within the month prior to and/or during the study,
  * were not pregnant, planning to become pregnant or breastfeeding,
  * had not significantly changed their physical activity in the 2-4 weeks prior to the study or who did not intend on changing them during the study,
  * were not receiving systemic or local treatment likely to interfere with the evaluation of the study parameters,

Exclusion Criteria:

* females aged below 18 and above 65 years
* BMI less than 25 kg/m2.
* smokers

  * had food allergies to the study foods,
  * had eating disorders,
  * were following a special diet (e.g. vegetarian, halal),
  * were taking any medication or supplements known to affect appetite or weight within the month prior to and/or during the study,
  * were pregnant, planning to become pregnant or breastfeeding,
  * had significantly changed their physical activity in the 2-4 weeks prior to the study or who did not intend on changing them during the study,
  * were receiving systemic or local treatment likely to interfere with the evaluation of the study parameters,
  * had a gastric band/had undergone gastric bypass treatment
  * and/or females who worked in appetite or feeding related areas.

Primary outcomes:
measure: Visual Analogue Scale measurements for Hunger
timeFrame: 9 hours
measure: Visual Analogue Scale measurements for Fullness
timeFrame: 9 hours
measure: Visual Analogue Scale measurements for Desire to Eat
timeFrame: 9 hours
measure: Visual Analogue Scale measurements for Prospective Food Consumption
timeFrame: 9 hours
measure: Energy intake after ad libitum buffet tea
timeFrame: 4 hours
measure: Macronutrient intake after ad libitum buffet tea
timeFrame: 4 hours
Secondary outcomes:
measure: Visual Analogue Scale measurements of thirst
timeFrame: 9 hours
measure: Visual Analogue Scale measurements of nausea
timeFrame: 9 hours
Other outcomes:
Locations:
city: Oxford
country: United Kingdom
facility: Oxford Brookes Centre for Nutrition and Health
Study officials:
affiliation: Solent University
name: Sarah Hillier, PhD
role: STUDY_DIRECTOR
References: