Clinical trial NCT04617301: Volumetric Analysis of Resorption Types on CBCT
Official title: Three-dimensional Volumetric/ Linear Analysis and Axial Classification of Root Resorptions Using Cone Beam Computed Tomography: A Retrospective Study
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Endodontic Disease
Tooth Resorption
Keywords: cone beam computed tomography
endodontics
tooth Resorption
Lead sponsor: Recep Tayyip Erdogan University Training and Research Hospital
Sponsor class: OTHER
First posted: 2020-11-05
Enrollment: 43
Sex: ALL
Minimum age (years): 12
Maximum age (years): 71
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CROSSOVER
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Cases of resorption that had CBCT images were included in the study. Radiographic features of resorption were defined in the images of 34 patients in accordance with these criteria. A total of 43 teeth with ECR (n=27), ERR (n=4), and IRR (n=12) were identified from 34 patients.

Brief summary: More accurate management of resorption can be achieved thanks to the three-dimensions volumetric and linear analysis, and the axial classification presented in this study.

Detailed description: The aim of this study was to investigate the volumetric and linear analysis, and to present the axial classification of root resorptions using cone beam computed tomography (CBCT).

A total of 43 teeth of external cervical resorption (ECR) (n=27), external replacement resorption (ERR) (n=4) and internal root resorption (IRR) (n=12) were identified from 34 patients. The volume of resorption and total tooth, the widest lengths of these resorptions, and the amount of thinnest dentin thickness around them were measured and compared according to age and sex. Additionally, the eight regional axial classification was performed and the percentages in these regions were evaluated. Significance was set at p=0.05 for statistical analysis.

More accurate management of resorption can be achieved thanks to the three-dimensions volumetric and linear analysis, and the axial classification presented in this study.

Eligibility criteria: Inclusion Criteria:

* Cases of resorption that had CBCT images

Exclusion Criteria:

* those presenting pathologic lesions, congenital/developmental anomalies or teeth with root canal filling
* those whose CBCT scans failed to present satisfactory quality.
* Additionally, SR, TAP, and EIR cases were excluded because their true dimensions could not be completely determined before resorption.

Primary outcomes:
measure: Volume of total tooth and resorbed area
timeFrame: for three months from the beginning of the study
measure: Measurement widest mesio-distal length, bucco-lingual length and corono-apical length of the resorbed lesion
timeFrame: for three months from the beginning of the study
measure: Linear measurements for thinnest dentin (buccal, distal, mesial and lingual/ palatinal) and resorbed area (mesio-distal length and bucco-lingual length) were made on axial sections
timeFrame: for three months from the beginning of the study
measure: The corono-apical length was measured on sagittal sections where the tooth axis was perpendicular to the ground plane.
timeFrame: for three months from the beginning of the study
measure: the axial section of the tooth was divided into eight parts and regional settlement classification was performed
timeFrame: for three months from the beginning of the study
Secondary outcomes:
Other outcomes:
Locations:
city: Rize
country: Turkey
facility: Recep Tayyip Erdogan University Training and Research Hospital
Study officials:
affiliation: Recep Tayyip Erdogan University Training and Research Hospital
name: Dilara Nil Günaçar
role: STUDY_CHAIR
References:
citation: Heithersay GS. Clinical, radiologic, and histopathologic features of invasive cervical resorption. Quintessence Int. 1999 Jan;30(1):27-37.
citation: Patel S, Dawood A, Wilson R, Horner K, Mannocci F. The detection and management of root resorption lesions using intraoral radiography and cone beam computed tomography - an in vivo investigation. Int Endod J. 2009 Sep;42(9):831-8. doi: 10.1111/j.1365-2591.2009.01592.x. Epub 2009 Jul 14.