Clinical trial NCT04041830: Validation of a French-version of the Leeds Food Preference Questionnaire in Normal Weight and Patients With Obesity
Official title: Validation of a French-version of the Leeds Food Preference Questionnaire in Normal Weight and Patients With Obesity
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Normal Weight Adults
Adults With Obesity
Keywords: Appetite
Food Reward
Methodological approach
Lead sponsor: University Hospital, Clermont-Ferrand
Sponsor class: OTHER
Collaborators: name: Appetite Control and Energy Balance Research Group, UNiversity of Leeds, Leeds, UK
name: Laboratoire AME2P. Campus universitaire des cezeaux, 63170 Aubiere, Cedex
First posted: 2019-08-01
Enrollment: 37
Sex: ALL
Minimum age (years): 20
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: While Food reward is an important component of the appetite control to consider, there is actually no tool that has been developed in French to perform its evaluation.

The Leeds Food Preference Questionnaire (LFPQ) is a validated and recognized tool to assess food reward, being however developed for British populations.

The aim of this work is to validate a French version of the LFPQ among lean and obese adults.

Detailed description: 50 lean and 50 patients with obesity between 20 and 55 years old (50% women and 50% men), will be recruited. After an evaluation of their body composition by impedance meter, and of their dietary status by questionnaires (TFEQ/DEBQ), they will be asked to perform twice the same experimental sessions. They will be asked during this session to arrive at 08:00 am after a 12-hour fast and will receive a calibrated breakfast. Before and after a lunch calibrated meal, they will be asked to perform the French version of the computerized questionnaire LFPQ. Appetite feelings will be assessed at regular intervals.

Eligibility criteria: Inclusion Criteria:

* BMI between 30 and 38 kg.m² for the obese patients and 20 and 25 for the lean ones.
* registered to the national social security system
* Signed consent

Exclusion Criteria:

* eating disorders
* metabolic disease such as hypertension and Type 2 diabetes

Primary outcomes:
measure: Change in Food reward
timeFrame: day 1 , day 8
Secondary outcomes:
measure: Body fat mass
timeFrame: day 0
measure: Body fat and fat free mass
timeFrame: day 0
measure: Dietary status
timeFrame: day 0
measure: Dietary status
timeFrame: day 0
measure: Hunger
timeFrame: day 1, day 1 + 30minutes, day 1+60minutes, day 1+ 90minutes , day 8, day 8 + 30minutes, day 8+60minutes, day 8+ 90minutes
measure: Satiety
timeFrame: dday 1, day 1 + 30minutes, day 1+60minutes, day 1+ 90minutes , day 8, day 8 + 30minutes, day 8+60minutes, day 8+ 90minutes
measure: desire to eat
timeFrame: day 1, day 1 + 30minutes, day 1+60minutes, day 1+ 90minutes , day 8, day 8 + 30minutes, day 8+60minutes, day 8+ 90minutes
measure: Prospective Food consumption
timeFrame: day 1, day 1 + 30minutes, day 1+60minutes, day 1+ 90minutes , day 8, day 8 + 30minutes, day 8+60minutes, day 8+ 90minutes
Other outcomes:
Locations:
city: Clermont-Ferrand
country: France
facility: Chu Clermont Ferrand
Study officials:
affiliation: University Hospital, Clermont-Ferrand
name: Elodie Gentes
role: PRINCIPAL_INVESTIGATOR
References: