Clinical trial NCT06374030: Retrospective Study of Airway Management in Dutch ED's
Official title: A Retrospective Study on the Practice and Safety of Airway Management in Dutch Emergency Departments
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Endotracheal Intubation
Lead sponsor: Frisius Medisch Centrum
Sponsor class: OTHER
Collaborators: name: VieCuri Medical Centre
name: Catharina Ziekenhuis Eindhoven
name: Rijnstate Hospital
name: Zuyderland Medical Centre
First posted: 2024-04-18
Enrollment: 1000
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: All patients who underwent endotracheal intubation between 01-01-2019 and 31-12-2023 in the participating ED's (Leeuwarden Medical Centre, VieCuri Medical Centre, Catharina Hospital, Rijnstate Hospital, Zuyderland Medical Centre)

Brief summary: Describing characteristics of the practice of airway management in Dutch emergency departments, including information about patient demographics, indications, performer characteristics, equipment and medication used and complications due to intubation.

Detailed description: Endotracheal intubation can be a lifesaving intervention for critically ill patients in the emergency department (ED). Endotracheal intubation is, however, a high-risk procedure with many potential complications, which seem to be even more prevalent when carried out in the ED compared to for example the operating theater. This is possibly due to multiple reasons such as a sicker population, non-elective setting, a higher variability among indications for intubation or competence of providers.

Internationally, large registries were established and multiple observational studies have been performed to gain more information about the methods, safety and complications of intubations in the ED. While in recent years these studies have added to our knowledge of ED airway management, there is still a lack of high-quality studies and there is a strong argument for increased research. To date, no studies have been published of airway management in Dutch EDs. The investigators therefore have no knowledge about any factors possibly influencing intubation outcomes and complications nor comparability with international data. Among these are factors that have been associated with preventable harm and death and insight into these factors could be used for improvement of the safety of airway management in Dutch EDs.

This study is therefore intended to provide a comprehensive review of the clinical practice and characteristics of endotracheal intubations within Dutch EDs. The results could potentially be used for comparative analysis against global datasets. Additionally, the insights gained from this study will shed light on existing gaps prevalent in the current registration processes of intubations in the Netherlands. Furthermore, these insights could act as a stepping stone for future investigations that can lead to a deeper understanding of the methodologies, safety protocols, and associated complications of endotracheal intubations within Dutch EDs

Eligibility criteria: Inclusion Criteria:

* All patients who underwent endotracheal intubation between 01-01-2019 and 31-12-2023 in the participating ED's

Exclusion Criteria:

* Patients for which no information about the intubation can be found in the electronic patient chart will be excluded from the study.

Primary outcomes:
measure: Different complications of endotracheal intubation
timeFrame: At the time of intervention and consequent 1 hour
Secondary outcomes:
Other outcomes:
measure: Intubator characteristics
timeFrame: At the time of intervention and consequent 1 hour
measure: Indication for intubation
timeFrame: At the time of intervention and consequent 1 hour
measure: Sedation agent used
timeFrame: At the time of intervention and consequent 1 hour
measure: Paralytic agent used
timeFrame: At the time of intervention and consequent 1 hour
measure: Sedative agent after intubation
timeFrame: At the time of intervention and consequent 1 hour
measure: Method of intubation
timeFrame: At the time of intervention and consequent 1 hour
measure: Patient characteristics
timeFrame: At the time of intervention and consequent 1 hour
Locations:
city: Leeuwarden
country: Netherlands
facility: Leeuwarden Medical Centre
Study officials:
References: