Clinical trial NCT01935440: A Comprehensive Approach to Secondary HIV Prevention and Care Among Positives
Official title: A Comprehensive Approach to Secondary HIV Prevention and Care Among Positives
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: HIV
Keywords: HIV, drug use
Lead sponsor: Johns Hopkins Bloomberg School of Public Health
Sponsor class: OTHER
Collaborators: name: National Institute on Drug Abuse (NIDA)
First posted: 2013-09-05
Enrollment: 632
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The goal of this study is to conduct an HIV prevention intervention to train HIV seropositive drug users to be peer health educators.

Detailed description: The primary objective of this funded research is to conduct an HIV prevention intervention to train HIV seropositive drug users to be peer health educators to: (1) recruit their high risk social network members for voluntary HIV counseling and testing (VCT) at the research clinic, (2) promote risk reduction among social network members, and (3) promote engagement in HIV care by encouraging HIV seropositive network members to schedule and keep HIV primary care appointments. There will be four types of participants in the Full Trial: 1) Index, 2) Testing Network 3) Longitudinal Network and 4) HIV positive network participants. This longitudinal study includes baseline, 6-months, and 12-month assessments

Eligibility criteria: Inclusion Criteria:

Index

1. 18 years old or older
2. documentation of HIV positive status
3. report one of following risk behaviors in past 90 days: sharing injection equipment, use of crack cocaine, or unprotected vaginal or anal sex

Testing network

1. 18 or older
2. provided testing coupon provided by an index participant

Longitudinal network participant-

1. tested HIV negative at the Lighthouse via redeeming a testing coupon
2. reported interacting with index who gave the coupon at least weekly
3. report one of following risk behaviors in the prior 90 days: sharing injection equipment, use of crack cocaine, or unprotected vaginal or anal sex

Positive Networks

1. HIV positive
2. report one of following risk behaviors in the prior 90 days: sharing injection equipment, use of crack cocaine, or unprotected vaginal or anal sex

Exclusion Criteria:

Index- already enrolled in the study as a Network participant

Testing network- already enrolled in the study as a Network participant

Longitudinal network- a) already enrolled in the study as a Network participant b) already enrolled in the study as a Index participant

Positive network- a) already enrolled in the study as a Network participant b) already enrolled in the study as a Index participant

Primary outcomes:
measure: change in HIV medication adherence
timeFrame: 6 month
measure: change in frequency in attending HIV medical appointments
timeFrame: 6 month
Secondary outcomes:
measure: change in sharing injection equipment
timeFrame: 6 month
measure: change in condom use
timeFrame: 6 month
Other outcomes:
Locations:
city: Baltimore
country: United States
facility: Lighhouse Studies @ Peer Point
state: Maryland
Study officials:
affiliation: Johns Hopkins Bloomberg School of Public Health
name: Carl A Latkin, PhD
role: PRINCIPAL_INVESTIGATOR
References: