Clinical trial NCT03297840: Change in Mindfulness in Borderline Personality Disorder
Official title: Change in Mindfulness in Borderline Personality Disorder After Dialectic-behavioural Therapy (DBT): A Pre-post-comparison
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Mindfulness
Borderline Personality Disorder
Lead sponsor: University of Oldenburg
Sponsor class: OTHER
First posted: 2017-09-29
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: Male and female BPD Patients from 18 to 60 years.

Brief summary: The current study aims to investigate the effect of dialectical behavioral therapy on mindfulness in patients with Borderline Personality Disorder. A treatment group will be compared to a waitlist control group.

Detailed description: Participants will be recruited from the Dialectical-Behavioral-Therapy (DBT) unit. DBT is a treatment approach that has been shown to be effective in the treatment of Borderline Personality Disorder. DBT integrates different psychotherapeutic interventions as well as Mindfulness Meditation exercises. Mindfulness is a meditation practice that can improve present moment awareness. When applied as therapeutic intervention mindfulness meditation can help patients to stay with their attention in the present moment, to be aware what is happening in the here and now, and to better identify and regulate upcoming emotions.

The current observational study investigates changes in symptom severity and mindfulness skills during DBT treatment. A treatment group will be compared to a waitlist control group. The two groups are predefined by routine medical care.

Symptom severity and mindfulness skills will be assessed at baseline (before treatment or when accepted for the waitlist) and after 12-weeks. A within and between group analyses will be performed.

Eligibility criteria: Inclusion Criteria:

* Clinical diagnosis of Borderline Personality Disorder
* On the waitlist for DBT treatment or actually treated with DBT
* Not previously treated with DBT.

Exclusion Criteria:

* Severe psychiatric comorbidity e.g. psychosis, severe depression, suicidality

Primary outcomes:
measure: Change in mindfulness
timeFrame: Baseline and after 12-weeks
measure: Change in borderline symptom severity
timeFrame: Baseline and after 12-weeks
measure: Change in overall psychiatric symptom severity
timeFrame: Baseline and after 12-weeks
measure: Change in severity in symptoms of depression
timeFrame: Baseline and after 12-weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Bad Zwischenahn
country: Germany
facility: Department of Psychiatry and Psychotherapy - University Hospital, University of Oldenburg
Study officials:
affiliation: Department of Psychiatry and Psychotherapy - University Hospital, University of Oldenburg, Oldenburg, Germany
name: Alexandra Philipsen, Prof.
role: PRINCIPAL_INVESTIGATOR
References:
citation: Storebo OJ, Stoffers-Winterling JM, Vollm BA, Kongerslev MT, Mattivi JT, Jorgensen MS, Faltinsen E, Todorovac A, Sales CP, Callesen HE, Lieb K, Simonsen E. Psychological therapies for people with borderline personality disorder. Cochrane Database Syst Rev. 2020 May 4;5(5):CD012955. doi: 10.1002/14651858.CD012955.pub2.