Clinical trial NCT00679640: Observational Usage and Efficacy Study of Candesartan in Heart Failure Treatment in France
Official title: Observational Usage and Efficacy Study of Candesartan in Heart Failure Treatment in France
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Heart Failure
Cohort Study
Keywords: candesartan
heart failure
cohort study
France
Lead sponsor: AstraZeneca
Sponsor class: INDUSTRY
Collaborators: name: Takeda
First posted: 2008-05-19
Enrollment: 450
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients seen in outpatient care (private consultation or outpatient hospital consultation) at the baseline visit

Brief summary: The purpose of this study is to describe the way candesartan is used in heart failure treatment in France (treatment initiation and monitoring), treatment stops occurrence and reasons for and patients clinical evolution


Eligibility criteria: Inclusion Criteria:

* outpatients to whom candesartan has been initiated for less than 30 days or during the consultation to treat heart failure

Exclusion Criteria:

* patients included in a clinical trial the last 30 days before consultation
* patients unable to answer the questions for linguistic or cognitive reasons
* patients who will be difficult to follow during the one year study

Primary outcomes:
measure: Profile of patients treated with candesartan for heart failure
timeFrame: At inclusion
Secondary outcomes:
measure: Percentage of patients taking correctly its treatment : indication, contraindication, drug titration, treatment monitoring
timeFrame: 6 and 12 months after
measure: Percentage of patients stopping its treatment and reasons why
timeFrame: 12 months after
measure: Percentage of hospitalisations due to heart failure and cardiovascular deaths
timeFrame: 12 months after
Other outcomes:
Locations:
city: Mulhouse Cedex 1
country: France
facility: Research Site
state: Alsace
city: Bordeaux
country: France
facility: Research Site
state: Aquitaine Nord
city: Dax Cedex
country: France
facility: Research Site
state: Aquitaine Sud
city: St Jean de Luz
country: France
facility: Research Site
state: Aquitaine Sud
city: Tarbes
country: France
facility: Research Site
state: Aquitaine Sud
city: Arras Cedex
country: France
facility: Research Site
state: Artois
city: Bethune
country: France
facility: Research Site
state: Artois
city: Besancon Cedex
country: France
facility: Research Site
state: Aube Franche Comte
city: Langres Cedex
country: France
facility: Research Site
state: Aube Franche Comte
city: Vesoul Cedex
country: France
facility: Research Site
state: Aube Franche Comte
city: Clermont Ferrand
country: France
facility: Research Site
state: Auvergne Stephanois
city: St Chamond
country: France
facility: Research Site
state: Auvergne Stephanois
city: St Etienne
country: France
facility: Research Site
state: Auvergne Stephanois
city: Caen Cedex 1
country: France
facility: Research Site
state: Basse Normandie
city: Caen Cedex 4
country: France
facility: Research Site
state: Basse Normandie
city: Granville Cedex
country: France
facility: Research Site
state: Basse Normandie
city: Mayenne Cedex
country: France
facility: Research Site
state: Basse Normandie
city: St Martin D Aubigny
country: France
facility: Research Site
state: Basse Normandie
city: Valognes
country: France
facility: Research Site
state: Basse Normandie
city: Dijon
country: France
facility: Research Site
state: Bourgogne
city: Dole Cedex
country: France
facility: Research Site
state: Bourgogne
city: Paray Le Monial Cedex
country: France
facility: Research Site
state: Bourgogne
city: Semur En Auxois
country: France
facility: Research Site
state: Bourgogne
city: Lannion Cedex
country: France
facility: Research Site
state: Bretagne Nord
city: Rennes
country: France
facility: Research Site
state: Bretagne Nord
city: Morlaix Cedex
country: France
facility: Research Site
state: Bretagne Sud
city: Bry Sur Marne Cedex
country: France
facility: Research Site
state: Brie
city: Meaux Cedex
country: France
facility: Research Site
state: Brie
city: Meaux
country: France
facility: Research Site
state: Brie
city: Savigny Sur Orge
country: France
facility: Research Site
state: Brie
city: Beziers Cedex
country: France
facility: Research Site
state: Catalogne
city: Beziers
country: France
facility: Research Site
state: Catalogne
city: Perpignan
country: France
facility: Research Site
state: Catalogne
city: Sete
country: France
facility: Research Site
state: Catalogne
city: Epernay
country: France
facility: Research Site
state: Champagne Ardennes
city: Chateau D Olonne
country: France
facility: Research Site
state: Charente
city: Niort
country: France
facility: Research Site
state: Charente
city: Poitiers Cedex
country: France
facility: Research Site
state: Charente
city: Royan
country: France
facility: Research Site
state: Charente
city: Annecy Le Vieux
country: France
facility: Research Site
state: Dauphine
city: Annemasse
country: France
facility: Research Site
state: Dauphine
city: Sallanches Cedex
country: France
facility: Research Site
state: Dauphine
city: Nice
country: France
facility: Research Site
state: Esterel
city: St Raphael
country: France
facility: Research Site
state: Esterel
city: Hazebrouck
country: France
facility: Research Site
state: Flandres
city: Lille Cedex
country: France
facility: Research Site
state: Flandres
city: Wattrelos Cedex
country: France
facility: Research Site
state: Flandres
city: Castelsarrasin
country: France
facility: Research Site
state: Gascogne
city: Montauban
country: France
facility: Research Site
state: Gascogne
city: Perigueux Cedex
country: France
facility: Research Site
state: Gascogne
city: Perigueux
country: France
facility: Research Site
state: Gascogne
city: Rouen
country: France
facility: Research Site
state: Haute Normandie
city: Boulogne Billancourt Cedex
country: France
facility: Research Site
state: Hauts de Seine
city: Arles
country: France
facility: Research Site
state: Languedoc
city: Montpellier
country: France
facility: Research Site
state: Languedoc
city: Nimes
country: France
facility: Research Site
state: Languedoc
city: Rodez
country: France
facility: Research Site
state: Languedoc
city: Villefranche de Rouergue
country: France
facility: Research Site
state: Languedoc
city: Limoges
country: France
facility: Research Site
state: Limousin
city: St Amand Montrond
country: France
facility: Research Site
state: Limousin
city: St Yrieix La Perche
country: France
facility: Research Site
state: Limousin
city: Nancy
country: France
facility: Research Site
state: Lorraine
city: St Avold
country: France
facility: Research Site
state: Lorraine
city: Bourgoin Jallieu
country: France
facility: Research Site
state: Lyonnais
city: Bron Cedex
country: France
facility: Research Site
state: Lyonnais
city: Gleize
country: France
facility: Research Site
state: Lyonnais
city: Lyon Cedex 03
country: France
facility: Research Site
state: Lyonnais
city: Rillieux La Pape Cedex
country: France
facility: Research Site
state: Lyonnais
city: Cogolin
country: France
facility: Research Site
state: Maures Corse
city: Hyeres
country: France
facility: Research Site
state: Maures Corse
city: Toulon Cedex
country: France
facility: Research Site
state: Maures Corse
city: Toulon
country: France
facility: Research Site
state: Maures Corse
city: Castanet Tolosan
country: France
facility: Research Site
state: Midi Pyrenees
city: Muret Cedex
country: France
facility: Research Site
state: Midi Pyrenees
city: Paris Cedex 04
country: France
facility: Research Site
state: Paris Centre
city: Paris Cedex 15
country: France
facility: Research Site
state: Paris Centre
city: Paris
country: France
facility: Research Site
state: Paris Centre
city: Aulnay Sous Bois
country: France
facility: Research Site
state: Paris Nord Est
city: Montfermeil
country: France
facility: Research Site
state: Paris Nord Est
city: Montreuil Cedex
country: France
facility: Research Site
state: Paris Nord Est
city: Montreuil
country: France
facility: Research Site
state: Paris Nord Est
city: Chateaubriant
country: France
facility: Research Site
state: Pays de Loire
city: Nantes
country: France
facility: Research Site
state: Pays de Loire
city: Amiens Cedex 3
country: France
facility: Research Site
state: Picardie
city: Conde Sur L Escaut
country: France
facility: Research Site
state: Picardie
city: Valenciennes Cedex
country: France
facility: Research Site
state: Picardie
city: Allauch Cedex
country: France
facility: Research Site
state: Provence
city: Marseille
country: France
facility: Research Site
state: Provence
city: Rognac
country: France
facility: Research Site
state: Provence
city: Salon de Provence Cedex
country: France
facility: Research Site
state: Provence
city: Salon de Provence
country: France
facility: Research Site
state: Provence
city: La Source
country: France
facility: Research Site
state: Sologne
city: Montargis
country: France
facility: Research Site
state: Sologne
city: Orleans
country: France
facility: Research Site
state: Sologne
city: Tonnerre
country: France
facility: Research Site
state: Sologne
city: Arpajon
country: France
facility: Research Site
state: Touraine
city: Chambray Les Tours Cedex
country: France
facility: Research Site
state: Touraine
city: Tours
country: France
facility: Research Site
state: Touraine
city: Villiers Sur Orge
country: France
facility: Research Site
state: Touraine
city: APT
country: France
facility: Research Site
state: Vallee Du Rhone
city: Chateaurenard
country: France
facility: Research Site
state: Vallee Du Rhone
city: Gap Cedex
country: France
facility: Research Site
state: Vallee Du Rhone
city: Beauchamp
country: France
facility: Research Site
state: Vexin
city: Beauvais Cedex
country: France
facility: Research Site
state: Vexin
city: Cergy
country: France
facility: Research Site
state: Vexin
city: Chelles
country: France
facility: Research Site
state: Vexin
city: Creil Cedex 1
country: France
facility: Research Site
state: Vexin
city: Pontoise
country: France
facility: Research Site
state: Vexin
city: Sarcelles
country: France
facility: Research Site
state: Vexin
city: Evecquemont
country: France
facility: Research Site
state: Yvelines
city: Gennevilliers
country: France
facility: Research Site
state: Yvelines
city: Maisons Laffitte
country: France
facility: Research Site
state: Yvelines
Study officials:
affiliation: CEMKA EVAL - Bourg La Reine - France
name: Stephane Bouee, MD, MSc
role: PRINCIPAL_INVESTIGATOR
affiliation: Hôpital Henri Mondor - Service de cardiologie - Créteil - France
name: Luc Hittinger, MD, Prof
role: STUDY_CHAIR
References: