Clinical trial NCT03661476: The Effect of Oculo-Motor Exercises in Intermittent Exotropia
Official title: Investigation of the Effect of Oculo-Motor Exercises in Intermittent Exotropic Children
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Intermittent Exotropia
Exercises
Keywords: Intermittent Exotropia
Oculo-Motor Exercises
Physiotherapy
Intermittent Exotropia Survey
Lead sponsor: Medipol University
Sponsor class: OTHER
First posted: 2018-09-07
Enrollment: 51
Sex: ALL
Minimum age (years): 2
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: In childhood strabismus, exotropia is most frequently seen with intermittent exotropia and convergence failure in the first decade of life. This situation adversely affects children's psychosocial development and creates worries about personal relationships and work life in their future lives. Patients' hesitant attitudes towards surgical treatment led to the out-of-surgery techniques such as exercise therapy. No studies have been found in the literature on the efficancy of the intermittent exotropia treatments with oculo-motor exercises. In our study, it was aimed to investigate the effects of oculo-motor exercises on intermittent exotropia in children.

Detailed description: 50 volunteer school-aged children between 2-17 years of age) were included in our study. Oculo-motor home exercise protocols were given to all participants for 2 sessions per day for 6 weeks, and regular phone calls were made once a week. Participants were assessed cycloplegic refraction by autorefractometry, corrected and uncorrected visual acuity by snellen chart, ocular motility test, near and distant alternating prism cover test, streopsis test and patient satisfaction levels by intermittent exotropia survery.

Eligibility criteria: Inclusion Criteria:

* Be between 2 and 17 years of age
* Intermittent exotropia diagnosis
* To have mental capacity in the level to understand and do exercises

Exclusion Criteria:

* Not complying with age criteria
* Constant exotropia
* Having undergone eye surgery
* Those with systemic disease that prevent exercise

Primary outcomes:
measure: Prism cover test
timeFrame: 6 weeks
Secondary outcomes:
measure: Streopsis test
timeFrame: 6 weeks
measure: Intermittent exotropia survery
timeFrame: 6 weeks
measure: Visual acuity
timeFrame: 6 weeks
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medipol University
state: Beykoz
Study officials:
affiliation: Faculty of Health Sciences
name: Candan Algun
role: STUDY_DIRECTOR
References:
citation: Govindan M, Mohney BG, Diehl NN, Burke JP. Incidence and types of childhood exotropia: a population-based study. Ophthalmology. 2005 Jan;112(1):104-8. doi: 10.1016/j.ophtha.2004.07.033.
citation: Joyce KE, Beyer F, Thomson RG, Clarke MP. A systematic review of the effectiveness of treatments in altering the natural history of intermittent exotropia. Br J Ophthalmol. 2015 Apr;99(4):440-50. doi: 10.1136/bjophthalmol-2013-304627. Epub 2014 Jul 7.
citation: Morimoto H, Asai Y, Johnson EG, Lohman EB, Khoo K, Mizutani Y, Mizutani T. Effect of oculo-motor and gaze stability exercises on postural stability and dynamic visual acuity in healthy young adults. Gait Posture. 2011 Apr;33(4):600-3. doi: 10.1016/j.gaitpost.2011.01.016. Epub 2011 Feb 19.