Clinical trial NCT04229238: Nutritional Status and Medication Treatment in Home-dwelling Older Adults
Official title: Nutrition and Medication Management in Home-dwelling Older Adults. Study I: Nutritional Status and Medication Treatment in Home-dwelling Older Adults. A Cross-sectional Study
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Malnutrition
Aged
Polypharmacy
Keywords: Nutritional status
Polypharmacy
Home-dwelling
Potentially inappropriate medication use
Lead sponsor: University of Oslo
Sponsor class: OTHER
Collaborators: name: The Norwegian Research Fund for General Practice
First posted: 2020-01-18
Enrollment: 400
Sex: ALL
Minimum age (years): 70
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Older adults (70 +) receiving regular health care from the home nurse service. Setting is two rural municipalities in southern Norway.

Brief summary: The project "Nutrition and Medication management in home-dwelling older adults" consist of two separate studies witch are described in the same study protocol. This is the first study in this Project. The second study is described separately; Identification: 2017/12883-2

Malnutrition is common in older adults. The causes are many and include adverse drug effects. Loss of appetite, nausea, or dry mouth are adverse drug effects, which may contribute to malnutrition. Knowledge about possible relations between drug treatment and nutritional status is scarce.

The objectives of the project is to describe nutritional status, drug treatment and the prevalence of potentially inappropriate medication in home-dwelling elderly receiving home care service in two Norwegian municipalities.

Detailed description: Recruitment by a the home nurse service. An informed content from the participant (or a close relative for those not able to give an informed consent) is required. A nurse will visit the participants and ask for information about six items concerning: food intake, weight loss, mobility, psychological stress, neuropsychological problems. The height and weight will be measured. A photo of the medicine prescription card will be taken. The investigators have created an online solution for collection of these sensitive data, including photos of the medication prescription card.

The data will automatically be stored in a secure database at the University of Oslo (TSD), for further analyses.

Eligibility criteria: Inclusion Criteria:

* Home-dwelling
* Be admitted to home-nursing service, every second week or more often.
* Age 70 or older
* Medication administrated by home nursing service.
* Informed consent by patient or close relative (next of kin)

Exclusion Criteria:

• Patient or next of kin denies inclusion

Primary outcomes:
measure: Nutritional status
timeFrame: week 1
measure: Potential Inappropriate medication
timeFrame: week 1
measure: Drugs with high risk for causing nausea, loss of appetite and dry mouth
timeFrame: week 1
Secondary outcomes:
Other outcomes:
Locations:
city: Oslo
country: Norway
facility: University of Oslo, Institute for Health and Society, Department of General Practice
Study officials:
affiliation: Institute of Health and Society, University of Oslo, Norway
name: Jørund Straand, professor
role: STUDY_CHAIR
References: