Clinical trial NCT05899426: Motor Learning-based Clinical Pilates Rehabilitation Protocol for Patients with Parkinson's Disease
Official title: Motor Learning-based Clinical Pilates Rehabilitation Protocol for Patients with Parkinson's Disease, Called @parkinsonpilates: Randomised Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Parkinson Disease
Keywords: Parkinson Disease
Exercise
Lead sponsor: European University of Lefke
Sponsor class: OTHER
First posted: 2023-06-12
Enrollment: 32
Sex: ALL
Minimum age (years): 45
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: 2 groups will receive different exercise program for 12 weeks.
Primary purpose: TREATMENT

Brief summary: Individuals with Parkinson's disease demonstrate impaired motor learning, including a slower acquisition rate and poor retention, which may result from deficits in cognitive function, especially executive function. Considering the reduced motor learning ability in this patient group, exercises should be designed with a focus on strengthening sensory inputs and basic functional training. Therefore, the investigators established this program according to previous experience published study \[NCT04063605\]. Therefore, the feasibility of this rehabilitation protocol, which combines motor learning and clinical pilates principles and is adapted to the needs of individuals with Parkinson's disease, will be examined.

Detailed description: The patients with Parkinson's Disease will be randomly assigned into two groups: Motor Learning based Clinical Pilates (MLCP) Group and Conventional Physiotherapy (CP) Group. Both groups will be treated for 12 weeks. The evaluation of the patients will be done before the beginning of exercise program, midterm evaluation in the 6th week and will be repeated at the end. Also there will be followed up evaluation with the same assessments at the 3rd month. Physical function/motor function of patients will be evaluated with The Unified Parkinson's Disease Rating Scale (UPDRS) III subscale, dynamic balance with Functional Reach Test (FRT), postural control and dynamic balance will also be evaluated with Berg Balance Scale and functional mobility by Timed Up and Go Test. Gait, balance and functional domains of the patients will be evaluated with Gait and Balance Scale (GABS), Nelson foot reaction test will be used for the reaction time.

Eligibility criteria: Inclusion Criteria:

* Having modified Hoehn \& Yahr Scale grade 2-3 symptoms
* Be over 45 years old
* Having a score of 24 or 24\< on the Mini Mental test
* To be able to read and write in Turkish
* Having at least 2 years Parkinson's Disease

Exclusion Criteria:

* Serious mental and psychological disorder
* Significant musculoskeletal disorders
* Lower extremity deformation
* Having another neurological disease
* Drug or dose change during treatment

Primary outcomes:
measure: Nelson Foot Reaction Test
timeFrame: 5 minutes
measure: Gait and Balance Scale (Untimed Tasks)
timeFrame: 15 minutes
measure: Gait and Balance Scale (Timed Tasks - Cadence)
timeFrame: 2 minutes
Secondary outcomes:
measure: Functional reach test
timeFrame: 5 minutes
measure: Timed-up and Go test
timeFrame: 5 minutes
measure: Berg Balance Scale
timeFrame: 15 minutes
measure: The Unified Parkinson&amp;amp;amp;amp;amp;#39;s Disease Rating Scale (UPDRS) III. Subscale
timeFrame: 15 minutes
Other outcomes:
Locations:
city: Mersin
country: Turkey
facility: European University of Lefke
Study officials:
affiliation: European University of Lefke
name: Beliz Belgen Kaygısız, PT, PhD
role: PRINCIPAL_INVESTIGATOR
affiliation: European University of Lefke
name: Fahriye Çoban, PT, MSc
role: PRINCIPAL_INVESTIGATOR
References: