Clinical trial NCT05315960: SOcial coNNEction in Long-Term Care Home Residents
Official title: SOcial coNNEction in Long-Term Care Home Residents
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Dementia
Keywords: Dementia
Long-term care
Outcome measurement
PROM
Psychometric
Lead sponsor: University College, London
Sponsor class: OTHER
Collaborators: name: University Health Network, Toronto
First posted: 2022-04-07
Enrollment: 220
Sex: ALL
Minimum age (years): 18
Maximum age (years): 110
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study will purposively sample participants for diverse representation, including with respect to age, sex, gender identity, sexual orientation, socioeconomic status, race, ethnicity, and, marital status. To ensure a range of demographic characteristics and to include traditionally under-represented groups, English language proficiency for people living with dementia, LTC residents and caregivers (e.g. family, friend) is not a requirement. Interpreters will be used for those not fluent in English and arranged through the institution's interpreter services.

Brief summary: This study aims to develop a new measure which can accurately assess social connection for people with dementia living in long-term care homes. The Social Connection in Long-term Care home residents (SONNET) study will use interviews and focus groups with people affected by dementia and long-term care residents to establish what aspects of social connection are important for people living in care homes. These findings and a review of other studies and measures will be used to develop a new measure or measures of social connection which will then be tested in a study based in care homes in Canada and the UK.

Detailed description: Research Question:

Can a new measure reliably and validly assess social connection for people with dementia in care homes?

Background:

Social connection, including objective and subjective constructs relating to human relationships, is a fundamental human need, but is impaired in people with dementia, particularly in those living in long-term care (LTC) settings due to cognitive impairment, complex health needs, and separation from previous social networks and community activities. Measurement instruments therefore need to be tailored to the distinct characteristics of this population and be tested in this setting, but there is no current evidence-based consensus on the best approaches to measurement.

Objectives:

1. Appraise existing measures of social connection used in LTC homes
2. Evaluate which aspects of social connection are considered important by people affected by dementia and professional staff
3. Develop a new measure informed by our appraisal of previous measures and the priorities of key stakeholders and test its preliminary psychometric properties

Methods:

A systematic review of measurement instruments assessing social connection in LTC residents, including dementia-specific measures will be conducted and measures will be appraised using COSMIN (COnsensus-based Standards for the selection of health Measurement INstruments) methodology. Focus groups and qualitative interviews will then be conducted with 50-70 people living with dementia, LTC residents, families, clinicians, care staff, and researchers in the UK and Canada to establish the important aspects of social connection and its measurement, including considerations for LTC residents with dementia and those with different stages of dementia severity. Findings from the systematic review and qualitative study will be used to inform the development of a measure or measures which will be iteratively refined during interviews. Finally, the new measure(s) will be tested for psychometric properties in 150 people with dementia living in LTC homes in the UK and Canada to establish acceptability, reliability, and validity.

Eligibility criteria: Qualitative study

Inclusion criteria:

* LTC residents with or without dementia: Able to provide consent for research.
* Caregivers: Visit the resident at least monthly (not including when COVID-related visitor restrictions are in place).
* Clinicians/care staff: Whose role currently includes working in LTC home or has done in past 2 years.
* Academic researchers: Have expertise in social functioning in dementia.
* All participants must be over the age of 18 years old to participate in the study.

Cross-sectional study Inclusion criteria

* LTC residents: Have a confirmed diagnosis of dementia OR Scoring ≥2 on the Noticeable Problems Checklist
* Proxy: Visit or care for the resident at least once monthly.
* All participants must be over the age of 18 years old and have adequate English language proficiency to participate in the study.

Primary outcomes:
measure: Resident Assessment Instrument-Minimum Data Set (RAI-MDS) Index of Social Engagement
timeFrame: 10 minutes
Secondary outcomes:
measure: Clinical Dementia Rating Scale
timeFrame: 10 minutes
measure: Neuropsychiatric Inventory
timeFrame: 10 minutes
measure: Katz Index of Independence in activities of Daily Living
timeFrame: 10 minutes
measure: Dementia-specific quality of life (DEMQOL-Proxy)
timeFrame: 10 minutes
measure: Family caregiver proxy-raters only will also be asked to completed the EQ5D
timeFrame: 5 minutes
Other outcomes:
Locations:
city: Toronto
country: Canada
facility: University Health Network
state: Ontario
city: London
country: United Kingdom
facility: Division of Psychiatry, University College London
Study officials:
References: