Clinical trial NCT05977374: Effects of Low Impact Elliptical Training on Knee Osteoarthritis Outcomes.
Official title: Effects of Low Impact Elliptical Training on Knee Osteoarthritis Outcomes.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoarthritis, Knee
Keywords: Knee osteoarthritis
Lead sponsor: Riphah International University
Sponsor class: OTHER
Collaborators: name: Health Education Research Foundation (HERF)
First posted: 2023-08-04
Enrollment: 28
Sex: ALL
Minimum age (years): 40
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This research study is determined to see the effects of low-impact elliptical training on knee osteoarthritis outcomes.

Detailed description: This study is designed to reduce the load of knee osteoarthritis patients in society so that the individual lives a healthy life without getting caught in any form of disability. Knee osteoarthritis is a progressive and degenerative disease of a joint that includes focal cartilage loss, bony hypertrophy, synovial capsule thickening, and changes in structures of periarticular ligaments and peripheral muscles.

There are several techniques used to overcome the individual's pain, for instance, the mobilization of the joint, prolotherapy, and the use of different electrical modalities. meanwhile, an elliptical workout provides a positive result in reducing the progression of overall knee joint and cartilage defects. elliptical training is included in low-impact activities which are proven joint-friendly activities for the better improvement of the knee joint.

This activity works on a similar principle of cyclic compressive loading as occurs in the manual mobilization of the knee joint. This activity brings out the fluid from the synovial membrane on compression and upon decompression, the cartilage reabsorbs the oxygen and nutrients, which crosses the synovial barrier into the synovial fluid through a double diffusion system in the joint. The fluid then reaches the extra-cellular matrix that moves to the multiple layers of chondrocytes for the growth of the cartilage in OA.

Eligibility criteria: Inclusion Criteria:

* 40- to 65-year-old.
* Diagnosed cases of Grade 1 and 2 Knee OA.
* Healthy and overweight patients will be included. (18.5- 29.5)

Exclusion Criteria:

* Acute musculoskeletal injury.
* Low back pain and Sciatica.
* Hip and ankle pathology.
* Acute infection, fever.
* The patient taking supplements and medications.
* Any knee deformity.

Primary outcomes:
measure: Knee joint pain.
timeFrame: Baseline, 6th week and 12th week.
measure: Knee joint X-rays.
timeFrame: Baseline, 6th week and 12th week.
measure: Knee joint stiffness and symptoms.
timeFrame: Baseline, 6th week and 12th week.
measure: Activities of daily livings impact on knee joint
timeFrame: Baseline, 6th week and 12th week.
measure: Sports activity impact on knee joint
timeFrame: Baseline, 6th week and 12th week.
measure: Quality of life impact on knee joint
timeFrame: Baseline, 6th week and 12th week.
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Islamabad Physical Therapy & Rehabilitation Centre
Study officials:
References: