Clinical trial NCT05144490: The Effect of Brief Bodyweight Exercise on Acute Glycemic Control in Healthy Inactive Adults
Official title: The Effect of Brief Bodyweight Exercise on Acute Glycemic Control in Healthy Inactive Adults
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Exercise
Keywords: Glycemic Control
Lead sponsor: McMaster University
Sponsor class: OTHER
Collaborators: name: York University
First posted: 2021-12-03
Enrollment: 35
Sex: ALL
Minimum age (years): 18
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Primary purpose: BASIC_SCIENCE

Brief summary: This study will investigate whether an 11-minute bodyweight exercise session can improve short-term glycemic control. Glycemic control refers to the process of how the body regulates blood sugar. The process can be measured in different ways. This study will use a small device called a continuous glucose monitor to measure changes in glucose levels over a 24-hour period. Participants will complete two trials and the investigators will compare glycemic control after the exercise session and a control period that does not involve exercise. Food intake will be controlled such that each participant will consume the same diet in both conditions. This study will help determine whether a single session of bodyweight exercise affects glycemic control.

Detailed description: This study will investigate whether an 11-minute bodyweight exercise session can improve short-term glycemic control. Glycemic control will be assessed using continuous glucose monitoring for 24 hours following exercise or a control condition that does not involve exercise. The exercise and control periods will be directly supervised by a study investigator. Participants will complete two trials in a randomized, crossover manner separated by 7 days. Food intake will be controlled such that each participant will consume the same diet over the 24-hour period of measurement in both conditions. Standardized meals will be provided to participants prior and following the exercise and control conditions. This study will determine whether a single session of bodyweight exercise affects glycemic control as primarily assessed by mean 24-hour glucose.

Eligibility criteria: Inclusion Criteria:

* Inactive, defined as not meeting the physical activity targets in the Canadian 24-Hour Movement Guidelines for Adults.
* Deemed able to safely participate in physical activity and exercise, as determined by the Canadian Society for Exercise Physiology (CSEP) Get Active Questionnaire prescreening tool.

Exclusion Criteria:

- Experiencing a condition that might preclude safe participation in physical activity and exercise, as determined by answering "Yes" to any question on Page 1 of the CSEP Get Active Questionnaire.

Primary outcomes:
measure: 24-hour mean glucose
timeFrame: 24-hour measurement period
Secondary outcomes:
measure: Glycemic variability
timeFrame: 24-hour measurement period
measure: Peak glucose
timeFrame: 2-hour measurement period after each meal
measure: 2-hour postprandial mean glucose
timeFrame: 2-hour measurement period after each meal
Other outcomes:
Locations:
city: Hamilton
country: Canada
facility: McMaster University
state: Ontario
Study officials:
affiliation: McMaster University
name: Martin Gibala, PhD
role: PRINCIPAL_INVESTIGATOR
References: