louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT04864626: Study of the Impact on the Evolution of the Disease in the Medium Term of the Implementation of a System of Extended Follow-up by Telephone Interview of Patients With an Eating Disorder Organized by the Nurses of the Eating Disorder Referral Center
Official title: Study of the Impact on the Evolution of the Disease in the Medium Term of the Implementation of a System of Extended Follow-up by Telephone Interview of Patients With an Eating Disorder Organized by the Nurses of the Eating Disorder Referral Center
Study type: OBSERVATIONAL
Overall status: ACTIVE_NOT_RECRUITING
Conditions: Eating Disorders
Recurrence
Relapse
Lead sponsor: Centre Hospitalier Universitaire de Saint Etienne
Sponsor class: OTHER
First posted: 2021-04-29
Enrollment: 250
Sex: ALL
Minimum age (years): 3
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patient with eating disorders

Brief summary: The referral center for eating disorders provides for a systematic many years follow-up of patients under care with an annual assessment at the center. The investigators have recently shown the frequency of relapse in the first 7 years after diagnosis, but the literature remains poor on this epidemiology and on the risk factors for relapse. The investigators would therefore like to extend this follow-up for an additional 3 years after remission with an annual telephone nursing interview for all cured patients.


Eligibility criteria: Inclusion Criteria:

* Patients diagnosed with an eating disorder confirmed at the multidisciplinary consultation meeting of the referring center and considered cured (in remission). For patients with Oral Disorders, inclusion is within one year of recovery
* Patient affiliated or entitled to a social security plan
* Oral participation agreement
* Pregnant women

Exclusion Criteria:

* Persons deprived of liberty
* Patients under guardianship or curatorship
* refusal to participate

Primary outcomes:
measure: Number of relapses/recurrences per year
timeFrame: 3 years
Secondary outcomes:
measure: risk factors for relapse/recurrence
timeFrame: 3 years
measure: Number of patients called per year
timeFrame: 3 years
measure: Number of calls made per patient per year
timeFrame: 3 years
measure: Number of completed calls per patient per year
timeFrame: 3 years
measure: Number of telephone sessions per year per patient
timeFrame: 3 years
measure: Duration of telephone sessions
timeFrame: 3 years
measure: Number of lost to follow-up per year
timeFrame: 3 years
measure: Number of patients not cured
timeFrame: 3 years
measure: Analysis of the experience of care questionnaire
timeFrame: 3 years
Other outcomes:
Locations:
city: Saint-etienne
country: France
facility: CHU de SAINT-ETIENNE
Study officials:
affiliation: CHU SAINT-ETIENNE
name: Marion POY, nurse
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01901926: Periodontal Treatment and Glycemic Control
Official title: Impact of Non Surgical Periodontal Treatment on Glycemic Control in Type II Diabetics
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Diabetes Mellitus Type 2
Lead sponsor: Pakistan Institute of Medical Sciences
Sponsor class: OTHER_GOV
First posted: 2013-07-17
Enrollment: 184
Sex: ALL
Minimum age (years): 20
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to determine the effects of non surgical periodontal treatment on glycemic control in type II diabetics.

Detailed description: The selected patients in treatment group will be given mechanical periodontal treatment in the form of scaling and root planning while the non intervention group patients will not receive treatment until the end of the trial.

Eligibility criteria: Inclusion Criteria:

* Diagnosed patients of Type 2 Diabetes Mellitus for at least 2 years
* HbA1C values \>6.5 % as per ADA criteria
* non smokers
* Patients with at least 16 standing teeth
* At least 8 teeth with one site having Mild to Moderate periodontal disease

Exclusion Criteria:

* Smokers
* Type 2 Diabetics with complications e.g. renal, ophthalmic etc
* Patients with chronic infections
* Patients who get hospitalized or have to change their medications during the course of study

Primary outcomes:
measure: Change in HbA1C levels from base line at 3, 6 and 9 months
timeFrame: 3 months, 6 months, 9 months
Secondary outcomes:
measure: Bleeding on Probing
timeFrame: Base Line, 3 months, 6 months and 9 months
measure: Clinical Attachment Loss
timeFrame: Base Line, 3 months, 6 months, 9 months
measure: Periodontal Pocket Depth
timeFrame: Base Line, 3 months, 6 months, 9 months
Other outcomes:
measure: Fasting Blood Glucose
timeFrame: Base Line, 3, 6 and 9 Months
measure: C-Reactive Protein
timeFrame: Base Line, 3 months, 6 months, 9 months
Locations:
city: Islamabad
country: Pakistan
facility: Pakistan Institute of Medical Sciences
state: Federal Capital
Study officials:
affiliation: Pakistan Institute of Medical Sciences
name: Salman Aziz, FCPS, MFDS
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT00309426: Effect of Fetuin A in Hemodialysis Patients
Official title: The Effect of Serum Fetuin A Concentration on the 5-Year Prognosis in Hemodialysis Patients
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Hemodialysis
Malnutrition
Keywords: atherosclerosis
Lead sponsor: University of Shizuoka
Sponsor class: OTHER
Collaborators: name: Maruyama Memorial General Hospital
First posted: 2006-03-31
Enrollment: 300
Sex: ALL
Minimum age (years): 0
Maximum age (years): 70
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: DEFINED_POPULATION
Time perspective: OTHER

Brief summary: The purpose of this study is to examined the effect of fetuin A on atherosclerosis and prognosis in hemodialysis patients.

Detailed description: Fetuin A is known to be a potent inhibitor of ectopic calcification in plasma, and the concentration of fetuin A is closely associated with protein nutritional status. The purpose of this study is to examine whether the plasma concentration of fetuin A is associated with atherosclerosis and 5-year prognosis in hemodialysis patients.

Eligibility criteria: Inclusion Criteria:

* Hemodialysis for at least 6 months

Exclusion Criteria:

* Disabled patients

Primary outcomes:
Secondary outcomes:
Other outcomes:
Locations:
city: Hamamatsu
country: Japan
facility: Maruyama Hospital
state: Shizuoka
Study officials:
affiliation: University of Shizuoka
name: Hiromichi Kumagai, MD
role: STUDY_CHAIR
References:
Clinical trial NCT05101226: Healthy University Bern Through Yoga - A Worksite Wellness Intervention
Official title: Healthy University Bern Through Yoga - A Worksite Wellness Intervention
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Healthy
Keywords: Employee
Worksite
Yoga
Wellness
Intervention
8 week
Perceived health
Stress
Well-being
Online
In Person
Lead sponsor: University of Bern
Sponsor class: OTHER
First posted: 2021-11-01
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Intervention model description: The participants will be randomly assigned either to the waiting list control group or the intervention group. The intervention group will be evenly split into the attending the yoga classes in person and attending them online.
Primary purpose: BASIC_SCIENCE

Brief summary: This study aims to research the effect of a 8-week long worksite yoga intervention on the perceived health of the University of Bern employees. Furthermore, in light of the current transition to online options, this study will compare the effects of yoga classes attended in person to those attended online.

Detailed description: After giving informed consent, the participants of the study will be randomly assigned to the intervention or waiting list control group. The intervention group will take part in a 8-week long yoga program before the christmas break, while the waiting list control group will receive the same intervention at the beginning of the new year. For both time periods the participants will be randomly assigned to the in person or the online group.

There will be four measurement times when all the participants will be asked to fill out an online questionnaire before and after both implementations of the intervention. The questionnaires include demographic data, perceived health (SF-8), perceived stress (PSS), well-being (BIT), physical activity questionaire (Godin Leisure-Time Exercise Questionnaire) as well as a questionnaire concerning the satisfaction of the intervention after the participants have actively taken part in the yoga intervention.

Eligibility criteria: Inclusion Criteria:

* Employee of the University of Bern
* Understanding German
* Ability to participate in 8 yoga classes

Exclusion Criteria:

-

Primary outcomes:
measure: Change in perceived health
timeFrame: 8 weeks
measure: Change in perceived stress
timeFrame: 8 weeks
measure: Change in well-being
timeFrame: 8 weeks
Secondary outcomes:
measure: Stability of change in perceived health
timeFrame: 12 weeks
measure: Stability of change in perceived stress
timeFrame: 12 weeks
measure: Stability of change in well-being
timeFrame: 12 weeks
Other outcomes:
Locations:
city: Bern
country: Switzerland
facility: Institute of Sport and Sportscience, University of Bern
Study officials:
affiliation: Institute for Sport and Sportscience, University of Bern
name: Claudio Nigg, Prof. Dr.
role: STUDY_DIRECTOR
References:
Clinical trial NCT06942026: Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa
Official title: Effects of Chlorhexidine Gluconate, Ozonated Water and Hypochlorous Acid Solutions Used in the Oral Care of Patients Supported by Mechanical Ventilation on the Integrity of the Oral Mucosa
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: PHASE4
Conditions: Oral Mucosal Disorder
Keywords: oral care
Intensive care unit
ozonated water
Oral Mucous Membrane
Lead sponsor: Aydin Adnan Menderes University
Sponsor class: OTHER
First posted: 2025-04-24
Enrollment: 63
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: The purpose of this clinical trial is to learn whether ozonated water and hypochlorous acid solution can restore the integrity of the oral mucosa. In addition, the investigators will learn about the safety of ozonated water and hypochlorous acid solution. The main questions that participants need to answer are:

What medical conditions do participants have while taking ozonated water and hypochlorous acid solution?

Investigators will compare ozonated water and hypochlorous acid solution with 0.12% chlorhexidine gluconate solution to see if it helps to restore the integrity of the oral mucosa.

Participants:

Participants will be asked to agree to receive oral care 4 times a day, every day for 1 week.


Eligibility criteria: Inclusion Criteria:

* Be between the ages of 18-65,
* Have been on mechanical ventilation for at least 24 hours,
* Have no intolerance or allergy to the solutions,
* Agree to participate in the study

Exclusion Criteria:

* Having a contraindication for oral care
* Not agreeing to participate in the study

Primary outcomes:
measure: oral assessment guide
timeFrame: From enrollment to the end of treatment at 1 week.
Secondary outcomes:
Other outcomes:
Locations:
city: Aydın
country: Turkey
facility: Aydın Adnan Menderes Univercity
Study officials:
References:
citation: Ozdemir S, Turk G. The effect of different concentrations of chlorhexidine on microbial colonization: A double-blinded randomized controlled study. Int J Nurs Pract. 2022 Apr;28(2):e13025. doi: 10.1111/ijn.13025. Epub 2021 Oct 23.
Clinical trial NCT02173626: Effect of Video-Module Based Mindfulness Training on Physician Stress and Well Being
Official title: Effect of Video-Module Based Mindfulness Training on Physician Stress and Well Being
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stress
Burnout
Mindfulness Skills
Keywords: Mindfulness
Lead sponsor: MultiCare Health System Research Institute
Sponsor class: OTHER
First posted: 2014-06-25
Enrollment: 23
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP

Brief summary: An eight week mindfulness training for physicians in a community hospital setting, largely administered through web-casts, will decrease stress and burnout, increase job satisfaction, and develop lasting mindfulness skills in the participants.

Detailed description: The purpose of this study was to evaluate the impact of a video-module based mindfulness pilot program on the stress, well-being, and mindfulness skills of physicians in a community hospital setting. We administered an eight-week mindfulness training in October/November of 2013, offered as part of a wellness initiative for medical staff in a suburban community hospital in Puyallup, Washington. Participants enrolled on a first-come, first-serve basis, engaging in three 90-minute in person trainings, weekly online video-module trainings, and weekly teleconference coaching calls. Video-module trainings were available at all times, to be accessed at the participants' convenience. Journals and a guided meditation audio library were also provided. Physician stress, well-being (emotional exhaustion, depersonalization of patients, sense of personal accomplishment), and mindfulness skills (observing, describing, acting with awareness, accepting without judgment) were evaluated at baseline, end-of-program, and eight weeks post-intervention using well-validated instruments. Risks to participants were minimal, including only the possibility of a strong emotional response to personal work undertaken by participants during the course of the study. The project was funded by MultiCare Health System.

Eligibility criteria: Inclusion Criteria:

* GSH medical staff member

Exclusion Criteria:

* Other MultiCare employees

Primary outcomes:
measure: Stress
timeFrame: Change from baseline stress at 16 weeks
Secondary outcomes:
measure: Burnout
timeFrame: Change from baseline burnout at 16 weeks
Other outcomes:
measure: Mindfulness Skills
timeFrame: Change from baseline mindfulness skills at 16 weeks
Locations:
city: Puyallup
country: United States
facility: Good Samaritan Hospital
state: Washington
Study officials:
affiliation: MultiCare Health System
name: Bethann M Pflugeisen, MS
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03190226: L-PRF for Increasing Keratinised Mucosa Around Implants
Official title: L-PRF Membranes for Increasing the Width of Keratinised Mucosa Around Implants: A Split-mouth, Randomized, Controlled Pilot Clinical Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Implantation Complication
Keywords: L-PRF
keratinised tissues
implant
free gingival graft
Lead sponsor: Universitaire Ziekenhuizen KU Leuven
Sponsor class: OTHER
First posted: 2017-06-16
Enrollment: 8
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Intervention model description: split-mouth trial
Primary purpose: TREATMENT

Brief summary: The aim of this study was to evaluate the potential of L-PRF in increasing the width of the keratinsed mucosa around implants. Furthermore, it was assessed whether this surgery was associated with significantly less post-operative discomfort for the patient compared to Free Gingival Graft surgery. L-PRF for increasing keratinised mucosa around implants.


Eligibility criteria: Inclusion Criteria:

* in need of bilateral enlargement of keratinsed tissues around implants

Exclusion Criteria:

* smokers

Primary outcomes:
measure: Amount of keratinised tissues
timeFrame: Measurements were performed pre-operatively (using lugol staining) and 3 months after surgery (using lugol staining). Results will be presented in the final paper.
Secondary outcomes:
measure: Post-op pain assessment
timeFrame: Visual analogue scales were handed out after surgery and were collected 1 week post-operatively. Results will be presented in the final paper.
Other outcomes:
Locations:
Study officials:
affiliation: Universitaire Ziekenhuizen KU Leuven
name: Gert-Jan Cleeren, MSc
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01353157: Study of the Clinical Scoring System and Cytokines for Prediction of Inflammatory Response in Major Surgery
Official title: Prediction for Systemic Inflammation With Clinical Scoring Systems and Inflammatory Cytokine Levels in Adult Cardiac and Major Abdominal Surgical Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Heart; Dysfunction Postoperative, Cardiac Surgery
Cytokine Release Syndrome
Keywords: cytokine
cardiac surgery
clinical scoring system
Lead sponsor: Khon Kaen University
Sponsor class: OTHER
First posted: 2011-05-12
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: adult patients who had undergone elective cardiac surgery with CPB

Brief summary: Cardiac surgery with cardiopulmonary bypass (CPB) and hepatic surgery are major operations, associated with a systemic inflammatory response syndrome. The aim of this study is to assess the effectiveness of clinical scoring systems and inflammatory cytokine levels for predicting systemic inflammation. This correlation might identify peri-operative clinical outcomes, then forecast further systemic inflammation in cardiac and hepatic surgical patients.

Detailed description: Systemic inflammatory response syndrome (SIRS) is commonly found in most major surgery. Early detection of SIRS will lead to early treatment. Serum cytokines levels are reliable markers for SIRS detection but with high cost and inconvenience. Clinical Scoring Systems are commonly used for assessment of patients with SIRS. If they have good correlation with cytokine levels, they might be used to predict peri-operative clinical outcomes.

Eligibility criteria: Inclusion Criteria:

* adult patients who had undergone elective cardiac surgery with CPB

Exclusion Criteria:

* under 18 years of age
* needing emergency surgery
* needing intra-aortic balloon pump

Primary outcomes:
measure: Correlation of clinical scoring systems and inflammatory cytokine levels
timeFrame: 24 h after CPB
Secondary outcomes:
Other outcomes:
Locations:
city: Khon Kaen
country: Thailand
facility: Queen Sirikit Heart Center of the Northeast, Khon Kaen University
Study officials:
affiliation: Faculty of Medicine, Khon Kaen University
name: Sirirat Tribuddharat, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01973257: Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.
Official title: Perfusion and Diffusion Mechanism of Intervertebral Disc-Significance With Age, Degeneration, Posture and Stress Loading.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Spinal Cord Injury, Degenerative Spinal Disease.
Lead sponsor: National Taiwan University Hospital
Sponsor class: OTHER
First posted: 2013-10-31
Enrollment: 50
Sex: ALL
Minimum age (years): 20
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Intervention model: PARALLEL
Primary purpose: DIAGNOSTIC

Brief summary: The purpose of our study is to evaluate the perfusion of the IVDs and their diffusion ability by using the Dynamic contrast-enhanced MR perfusion technique and Diffusion weighted image with ADC value measurement, and to determine the relationship between these data and the degeneration of IVDs, the different posture, and different stress-loading status.


Eligibility criteria: Inclusion Criteria:

* Patients with a diagnosis of spinal cord injury and degenerative spinal disease
* Normal volunteers

Exclusion Criteria:

- Patients with cancer and infection.

Primary outcomes:
measure: Disc Perfusion
timeFrame: 3 months
Secondary outcomes:
Other outcomes:
Locations:
city: Taipei
country: Taiwan
facility: Tiffany Ting-Fang Shih
Study officials:
affiliation: Department of Medical Image, National Taiwan University Hospital
name: Tiffany Ting-Fang Shih
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06332326: Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients
Official title: Investigation of the Efficacy of Non-Invasive Vagus Nerve Stimulation and Physiotherapy in Unilateral Vestibular Hypofunction Patients
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Vestibular Diseases
Vestibular Vertigo
Vertigo
Keywords: unilateral vestibular hypofunction
Non-Invasive Vagus Nerve Stimulation
balance
vestibular rehabilitation
Lead sponsor: Medipol University
Sponsor class: OTHER
First posted: 2024-03-27
Enrollment: 40
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: 40 patients diagnosed with UHV were included. Patients were randomized into 2 separate groups (20 people in the vestibular rehabilitation group, 20 people in the vagus nerve stimulation group in addition to vestibular rehabilitation).
Primary purpose: TREATMENT

Brief summary: The purpose of this study: To investigate the effectiveness of non-invasive vagus nerve stimulation and vestibular rehabilitation applications in patients diagnosed with Unilateral Vestibular Hypofunction (UVH).

Detailed description: It was planned to include 40 patients diagnosed with UHV in the study. Patients were randomized into 2 separate groups (20 people in the vestibular rehabilitation group, 20 people in the vagus nerve stimulation group in addition to vestibular rehabilitation).

Eligibility criteria: Inclusion Criteria:

* He learned about unilateral peripheral vestibular hypofunction with videonystagmography
* Being able to communicate well

Exclusion Criteria:

* Having cognitive impairment
* Presence of central neurological disease
* Lack of cooperation
* Previous ear surgery
* Accompanied by Benign Proxysmal Positional Vertigo
* Having acute Meniere's disease
* Finding pathology in temporal bone MRI
* Having a lower extremity disorder that prevents walking
* Evidence of central pathology in videonystagmography results

Primary outcomes:
measure: Modified-CTSIB
timeFrame: 30 minutes
measure: Semitandem test
timeFrame: 10 minutes
measure: tandem test
timeFrame: 10 minutes
measure: one-leg standing test
timeFrame: 10 minutes
measure: Unterberger test
timeFrame: 5 minutes
measure: VAS Visual Analogue Scale (dizziness severity)
timeFrame: 5 minutes
measure: Dynamic visual acuity test
timeFrame: 5 minutes
Secondary outcomes:
measure: Dizziness Handicap Inventory Scale
timeFrame: 5 minutes
measure: Tampa Kinesiophobia Scale
timeFrame: 5 minutes
measure: Hospital Anxiety and Depression Scale (HAD)
timeFrame: 5 minutes
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Istanbul Medipol University
Study officials:
affiliation: Medipol University
name: tuğba türk kalkan, MD
role: PRINCIPAL_INVESTIGATOR
References: