Clinical trial NCT05445362: Efficacy of Diode Laser in Maturogenesis of Immature Teeth With Necrotic Pulps
Official title: Evaluation of the Efficacy of Diode Laser in Maturogenesis of Immature Teeth With Necrotic Pulps: A Preliminary Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Effects of the Elements
Keywords: Diode Laser, Revascularization, Immature Necrotic Teeth.
Lead sponsor: Minia University
Sponsor class: OTHER
First posted: 2022-07-06
Enrollment: 39
Sex: ALL
Minimum age (years): 8
Maximum age (years): 16
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Recruited patients with immature permanent maxillary anterior teeth with non-vital pulp, and periapical radiolucency, age ranging from 8 to16 years old were randomly allocated into three groups (n=13): Group I, disinfected using the triple antibiotic paste, Group II, disinfection was done using diode laser, and Group III, were disinfected using the triple antibiotic paste, diode laser was used for biostimulation. All groups were evaluated for the increase in root length and thickness and decrease in apical diameter at baseline, 3, 6, 9, and 12 months after treatment

Detailed description: * The investigator recruited patients who are found eligible to the criteria then randomly allocated into three groups (n=13)
* Group I: thirteen teeth were disinfected by triple antibiotic paste then revascularization was done using the blood clot method.
* Group II: thirteen teeth were Laser disinfected; revascularization was done using the the blood clot method.
* Group III: thirteen teeth were disinfected by triple antibiotic paste then revascularization was done using the the blood clot method followed by diode laser bio-stimulation.
* periapical x rays was taken at baseline, 3, 6, 9, and 12 months after treatment for the increase in root length and thickness, decrease in apical diameter evaluation

Eligibility criteria: Inclusion Criteria:

* Medically free patients.
* Immature permanent maxillary anterior teeth.
* Non vital pulp.
* patents age between 8-16 years.
* Both sexes.
* Restorable teeth.
* No internal or external root resorption.
* No horizontal or vertical root fracture
* Radiographic periapical radiolucency
* No history of previous endodontic treatment of the tooth.

Exclusion Criteria:

* Medically compromised patients
* Previous endodontic therapy of the affected tooth.
* Teeth diagnosed with vital pulp.
* Teeth with periodontal pocket more than 3mm deep.
* Teeth with caries below the bony level (non-restorable tooth).
* Mature teeth with complete apices.

Primary outcomes:
measure: The change in root length evaluation
timeFrame: at baseline, 3, 6, 9, and 12 months after treatment
Secondary outcomes:
measure: The change in root thickness
timeFrame: At base line , 3, 6, 9, and 12 month after treatment
measure: The change in apical diameter
timeFrame: At base line, 3, 6, 9, and 12 month after treatment
Other outcomes:
Locations:
city: Minya
country: Egypt
facility: Faculty of Oral and dental medicine, Minia University
Study officials:
affiliation: Minia University
name: Reham Hassan, Assoc, prof
role: STUDY_DIRECTOR
References: