Clinical trial NCT06003426: A Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
Official title: A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary Fibrosis
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: PHASE3
Conditions: Idiopathic Pulmonary Fibrosis
Keywords: BMS-986278
LPA1 antagonist
IPF
Pulmonary fibrosis
Lead sponsor: Bristol-Myers Squibb
Sponsor class: INDUSTRY
First posted: 2023-08-22
Enrollment: 1185
Sex: ALL
Minimum age (years): 40
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to evaluate the efficacy, safety, and tolerability of BMS-986278 in participants with Idiopathic Pulmonary Fibrosis.


Eligibility criteria: Inclusion Criteria

* Subjects with IPF aged ≥ 40 years at the time of signing the informed consent.
* Diagnosis of IPF within 7 years prior to screening that is supported by centrally read chest high-resolution computed tomography (HRCT) obtained at screening and verification of usual interstitial pneumonia.
* If on pirfenidone or nintedanib, participants must have been on a stable dose for at least 90 days prior to screening.
* If not currently on pirfenidone or nintedanib, participants must not have received either of these medications within 28 days prior to screening.
* Women who are of childbearing potential must have a highly effective form of contraception and must provide a negative urine/serum pregnancy test.
* Men who are sexually active with women of childbearing potential agree to use male barrier contraception.

Exclusion Criteria

* History of stroke or transient ischemic attack within 3 months prior to screening.
* Participants who exhibit symptoms of heart failure at rest.
* Participants who have a current malignancy or a previous malignancy with less than 2 years free of recurrence or a biopsy that is suspicious for malignancy and the possibility of malignancy cannot be reasonably excluded following additional clinical, laboratory, or other diagnostic evaluations.
* Other protocol-defined Inclusion/Exclusion criteria apply.

Primary outcomes:
measure: Number of participants that experience spontaneous syncopal events
timeFrame: At approximately 4 weeks
measure: Absolute change from baseline in forced vital capacity (FVC) measured in mL
timeFrame: Up to Week 52
Secondary outcomes:
measure: Number of participants who discontinued treatment due to any low BP-related Adverse Events
timeFrame: Up to approximately 3 years
measure: Disease progression
timeFrame: Up to approximately 3 years
measure: Change from baseline in Living with Pulmonary Fibrosis Questionnaire (L-PF) cough domain score
timeFrame: Up to Week 52
measure: Change from baseline in L-PF dyspnea domain score
timeFrame: Up to Week 52
measure: Change from baseline in walking distance measured in 6-minute walk test (6MWT)
timeFrame: Up to Week 52
measure: Time to the first occurrence of any of the components of the composite endpoint: time to first acute exacerbation of pulmonary fibrosis, first Respiratory-related hospitalization, or all-cause mortality
timeFrame: Up to approximately 3 years
measure: Time to absolute percent ppFVC decline of ≥ 10% from baseline
timeFrame: Up to approximately 3 years
measure: Time to first acute exacerbation of pulmonary fibrosis
timeFrame: Up to approximately 3 years
measure: Time to first Respiratory-related hospitalization
timeFrame: Up to approximately 3 years
measure: Time to first pulmonary fibrosis-related hospitalization
timeFrame: Up to approximately 3 years
measure: Time to death
timeFrame: Up to approximately 3 years
measure: Change from baseline in L-PF fatigue domain score
timeFrame: Up to Week 52
measure: Change from baseline in L-PF impacts module score
timeFrame: Up to Week 52
measure: Change from baseline in cough numeric rating scale (NRS)
timeFrame: Up to Week 52
measure: Change from baseline in EuroQol 5 Dimension 5 Level (EQ-5D-5L) health utility index score
timeFrame: Up to Week 52
measure: Change from baseline in EQ-5D-5L visual analog scale score
timeFrame: Up to Week 52
measure: Rate of decline from baseline in FVC (mL)
timeFrame: Up to Week 52
measure: Rate of decline in ppFVC from baseline
timeFrame: Up to Week 52
measure: Change in ppFVC from baseline
timeFrame: Up to Week 52
measure: Proportion of participants with absolute decline in ppFVC ≥10%
timeFrame: Up to Week 52
measure: Proportion of participants with relative decline in ppFVC ≥10%
timeFrame: Up to Week 52
measure: Change from baseline in single-breath diffusing capacity of the lung for carbon monoxide (DLCO SB) (corrected for hemoglobin) (mL/min/mm Hg)
timeFrame: Up to Week 52
measure: Change in percent predicted single breath diffusing capacity of the lung for carbon monoxide (ppDLCO SB) (corrected for hemoglobin) from baseline
timeFrame: Up to Week 52
measure: Change from baseline in quantitative lung fibrosis (QLF) score via high-resolution computed tomography (HRCT)
timeFrame: Up to Week 52
measure: Number of participants with Adverse Events (AEs)
timeFrame: Up to 28 days after last dose
measure: Number of participants with Serious AEs (SAEs)
timeFrame: Up to 28 days after last dose
measure: Number of participants with AEs leading to early discontinuation of investigational medicinal product (IMP)
timeFrame: Up to 28 days after last dose
measure: Number of participants with AEs related to IMP
timeFrame: Up to 28 days after last dose
measure: Number of treatment-emergent deaths
timeFrame: Up to 28 days after last dose
measure: Number of participants with clinical laboratory abnormalities
timeFrame: Up to 28 days after last dose
measure: Number of participants with electrocardiogram (ECG) abnormalities
timeFrame: Up to 28 days after last dose
measure: Number of participants with vital sign abnormalities
timeFrame: Up to 28 days after last dose
measure: Number of participants with physical examination abnormalities
timeFrame: Up to 28 days after last dose
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: The University of Alabama at Birmingham
state: Alabama
city: Jasper
country: United States
facility: Local Institution - 0179
state: Alabama
city: Phoenix
country: United States
facility: St. Joseph's Hospital and Medical Center
state: Arizona
city: La Jolla
country: United States
facility: Scripps Clinic Torrey Pines
state: California
city: La Jolla
country: United States
facility: Local Institution - 0112
state: California
city: Los Angeles
country: United States
facility: University of Southern California (USC) - Keck School of Medicine (KSOM) - Transplant Clinic
state: California
city: Los Angeles
country: United States
facility: David Geffen School of Medicine at UCLA
state: California
city: Newport Beach
country: United States
facility: Local Institution - 0501
state: California
city: Orange
country: United States
facility: UC Irvine Medical Center
state: California
city: Sacramento
country: United States
facility: University of California UC Davis Medical Center
state: California
city: San Francisco
country: United States
facility: University of California, San Francisco Medical Center- Pulmonary Practice
state: California
city: Stanford
country: United States
facility: Stanford University School of Medicine
state: California
city: Aurora
country: United States
facility: University of Colorado Anschutz Medical Campus - Department of Family Medicine
state: Colorado
city: Denver
country: United States
facility: National Jewish Health
state: Colorado
city: New Haven
country: United States
facility: Yale New Haven Hospital
state: Connecticut
city: Newark
country: United States
facility: Christiana Care Pulmonary Associates - Newark
state: Delaware
city: Washington
country: United States
facility: Medstar Georgetown University Hospital
state: District of Columbia
city: Brandon
country: United States
facility: Meris Clinical Research
state: Florida
city: Clearwater
country: United States
facility: St Francis Sleep Allergy & Lung Institute
state: Florida
city: DeBary
country: United States
facility: Omega Research Consultants LLC
state: Florida
city: Gainesville
country: United States
facility: Local Institution - 0060
state: Florida
city: Gainesville
country: United States
facility: University of Florida (UF) Health Shands Hospital
state: Florida
city: Hialeah
country: United States
facility: Harmony Medical Research Institute, Inc
state: Florida
city: Kissimmee
country: United States
facility: Clinical Research Specialists, LLC - Kissimmee
state: Florida
city: Leesburg
country: United States
facility: Local Institution - 0502
state: Florida
city: Loxahatchee Groves
country: United States
facility: Pulmonary Specialists of the Palm Beaches
state: Florida
city: Miami
country: United States
facility: Local Institution - 0401
state: Florida
city: Ocala
country: United States
facility: Ocala Lung & Critical Care
state: Florida
city: Pensacola
country: United States
facility: Avanza Medical Research Center
state: Florida
city: Saint Petersburg
country: United States
facility: Coastal Pulmonary & Critical Care, P.L.C.
state: Florida
city: Tampa
country: United States
facility: University of South Florida
state: Florida
city: Weston
country: United States
facility: Local Institution - 0412
state: Florida
city: Atlanta
country: United States
facility: Local Institution - 0452
state: Georgia
city: Dublin
country: United States
facility: Pulmonology, Sleep, Asthma & Allergy Center of Dublin
state: Georgia
city: Chicago
country: United States
facility: Northwestern Memorial Hospital
state: Illinois
city: Chicago
country: United States
facility: Rush University Medical Center - Rush Pulmonary and Critical Care Medicine - Professional Building
state: Illinois
city: Chicago
country: United States
facility: The University of Chicago Medicine
state: Illinois
city: Evanston
country: United States
facility: Local Institution - 0094
state: Illinois
city: Maywood
country: United States
facility: Loyola University Health System
state: Illinois
city: Peoria
country: United States
facility: OSF Saint Francis Medical Center
state: Illinois
city: Indianapolis
country: United States
facility: Local Institution - 0190
state: Indiana
city: Iowa City
country: United States
facility: University of Iowa Hospitals and Clinics
state: Iowa
city: Kansas City
country: United States
facility: University of Kansas Medical Center (KUMC)
state: Kansas
city: Louisville
country: United States
facility: Norton Pulmonary Specialists
state: Kentucky
city: Louisville
country: United States
facility: Local Institution - 0435
state: Kentucky
city: Baltimore
country: United States
facility: University of Maryland - Marlene and Stewart Greenebaum Cancer Center
state: Maryland
city: Towson
country: United States
facility: Local Institution - 0043
state: Maryland
city: Boston
country: United States
facility: Massachusetts General Hospital
state: Massachusetts
city: Boston
country: United States
facility: Local Institution - 0439
state: Massachusetts
city: Boston
country: United States
facility: Steward St. Elizabeth Medical Center
state: Massachusetts
city: Springfield
country: United States
facility: Local Institution - 0195
state: Massachusetts
city: Ann Arbor
country: United States
facility: University of Michigan
state: Michigan
city: Detroit
country: United States
facility: Local Institution - 0455
state: Michigan
city: Grand Rapids
country: United States
facility: Local Institution - 0078
state: Michigan
city: Royal Oak
country: United States
facility: Local Institution - 0493
state: Michigan
city: Chesterfield
country: United States
facility: The Lung Research Center
state: Missouri
city: Saint Louis
country: United States
facility: Washington University School of Medicine in St. Louis
state: Missouri
city: Newark
country: United States
facility: Local Institution - 0384
state: New Jersey
city: Mount Kisco
country: United States
facility: Northern Westchester Hospital
state: New York
city: New York
country: United States
facility: Local Institution - 0487
state: New York
city: New York
country: United States
facility: Local Institution - 0387
state: New York
city: Durham
country: United States
facility: Duke University Medical Center
state: North Carolina
city: Wilmington
country: United States
facility: Accellacare US Inc. of Wilmington
state: North Carolina
city: Winston-Salem
country: United States
facility: Southeastern Research Center
state: North Carolina
city: Cincinnati
country: United States
facility: University of Cincinnati College Of Medicine
state: Ohio
city: Columbus
country: United States
facility: The Ohio State University Wexner Medical Center
state: Ohio
city: Toledo
country: United States
facility: Mercy St. Vincent Medical Center
state: Ohio
city: Oklahoma City
country: United States
facility: OU Health Sciences Center - OU Health Physicians - Cardiology, Pulmonary & Vascular Medicine Clinic
state: Oklahoma
city: Tulsa
country: United States
facility: Layrek Clinical Research
state: Oklahoma
city: Portland
country: United States
facility: Oregon Health & Science University - Pulmonary Clinic
state: Oregon
city: Hershey
country: United States
facility: Penn State Milton S. Hershey Medical Center
state: Pennsylvania
city: Philadelphia
country: United States
facility: Penn Medicine - Perelman Center for Advanced Medicine
state: Pennsylvania
city: Philadelphia
country: United States
facility: Thomas Jefferson University Hospital - Jane and Leonard Korman Lung Center
state: Pennsylvania
city: Philadelphia
country: United States
facility: Temple University Hospital (TUH) - Temple Lung Center (TLC)
state: Pennsylvania
city: Pittsburgh
country: United States
facility: UPMC - Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases (ILD)
state: Pennsylvania
city: Wynnewood
country: United States
facility: Lankenau Medical Center
state: Pennsylvania
city: Anderson
country: United States
facility: AnMed Health Oglesby Center - AnMed Health Pulmonary and Sleep Medicine
state: South Carolina
city: Charleston
country: United States
facility: Medical University of South Carolina- College of Medicine
state: South Carolina
city: Rock Hill
country: United States
facility: Local Institution - 0182
state: South Carolina
city: Nashville
country: United States
facility: Vanderbilt Lung Institute - One Hundred Oaks
state: Tennessee
city: Nashville
country: United States
facility: Local Institution - 0390
state: Tennessee
city: Dallas
country: United States
facility: University of Texas Southwestern Medical Center - Pulmonary Specialty Clinic
state: Texas
city: Dallas
country: United States
facility: Baylor University Medical Center at Dallas
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine Medical Center - Pulmonary, Critical Care, and Sleep Medicine
state: Texas
city: Houston
country: United States
facility: McGovern Medical School - UT Physicians - Pulmonary Medicine - Texas Medical Center Location
state: Texas
city: McKinney
country: United States
facility: Metroplex Pulmonary and Sleep Center
state: Texas
city: San Antonio
country: United States
facility: South Texas Veterans Health Care System - Audie L. Murphy VA Hospital
state: Texas
city: Salt Lake City
country: United States
facility: University of Utah, University Hospital
state: Utah
city: Falls Church
country: United States
facility: Local Institution - 0489
state: Virginia
city: Richmond
country: United States
facility: VCU Medical Center
state: Virginia
city: Everett
country: United States
facility: Western Washington Medical Group (WWMG) - Everett - Silver Lake Medical Center Location
state: Washington
city: Seattle
country: United States
facility: University of Washington Medical Center
state: Washington
city: Milwaukee
country: United States
facility: Local Institution - 0192
state: Wisconsin
city: Mar Del Plata
country: Argentina
facility: Fundacion Enfisema - Instituto Ave Pulmo
state: Buenos Aires
city: San Fernando
country: Argentina
facility: Local Institution - 0449
state: Buenos Aires
city: Buenos Aires
country: Argentina
facility: Fundacion Respirar
state: B
city: Caba
country: Argentina
facility: Consultorios Médicos del Buen Ayre
state: B
city: Florencio Varela
country: Argentina
facility: Instituto De Enfermedades Respiratorias E Investigacion Medica (IERIM)
state: B
city: Florida
country: Argentina
facility: Centro Medico de Enfermedades Respiratorias
state: B
city: Mar del Plata
country: Argentina
facility: Clinica 25 de Mayo
state: B
city: Quilmes, Provincia De Buenos Aires
country: Argentina
facility: Centro Respiratorio Quilmes
state: B
city: Ciudad Autónoma Buenos Aires
country: Argentina
facility: Hospital Italiano de Buenos Aires
state: C
city: Godoy Cruz
country: Argentina
facility: Respira Salud Clinica Integral
state: M
city: Mendoza
country: Argentina
facility: Fundacion Scherbovsky
state: M
city: Mendoza
country: Argentina
facility: Instituto Medico INSARES SA
state: M
city: Rosario
country: Argentina
facility: Instituto Medico de la Fundacion de Estudios Clínicos
state: S
city: San Miguel De Tucumán
country: Argentina
facility: Investigaciones en Patologias Respiratorias
state: T
city: Cordoba
country: Argentina
facility: Instituto Medico DAMIC
state: X
city: Buenos Aires
country: Argentina
facility: Local Institution - 0446
city: Ciudad Autónoma de Buenos Aires
country: Argentina
facility: Centro de Investigaciones Metabólicas (CINME)
city: Santa Fe
country: Argentina
facility: Ibamedica
city: Camperdown
country: Australia
facility: Royal Prince Alfred Hospital
state: New South Wales
city: Darlinghurst
country: Australia
facility: Local Institution - 0293
state: New South Wales
city: Westmead
country: Australia
facility: Westmead Hospital
state: New South Wales
city: Brisbane
country: Australia
facility: The Prince Charles Hospital
state: Queensland
city: Chermside
country: Australia
facility: Local Institution - 0474
state: Queensland
city: Greenslopes
country: Australia
facility: Gallipoli Medical Research Centre - Clinical Trials Unit (CTU)
state: Queensland
city: South Brisbane
country: Australia
facility: Mater Misericordiae Limited
state: Queensland
city: Adelaide
country: Australia
facility: Royal Adelaide Hospital
state: South Australia
city: Box Hill
country: Australia
facility: Eastern Health
state: Victoria
city: Frankston
country: Australia
facility: Peninsula Health - Frankston Hospital
state: Victoria
city: Heidelberg
country: Australia
facility: Local Institution - 0357
state: Victoria
city: Melbourne
country: Australia
facility: Local Institution - 0253
state: Victoria
city: Murdoch
country: Australia
facility: Fiona Stanley Hospital
state: Western Australia
city: Nedlands
country: Australia
facility: Institute for Respiratory Health
state: Western Australia
city: Linz
country: Austria
facility: Kepler Universitatsklinikum
state: Oberoesterreich
city: Salzburg
country: Austria
facility: SALK - Universitatsklinik Fur Pneumologie/ Lungenheilkunde Landeskrankenhaus
state: Salzburger Land
city: Graz
country: Austria
facility: Local Institution - 0460
state: Styria
city: Vienna
country: Austria
facility: Local Institution - 0082
city: Wien
country: Austria
facility: Krankenhaus Hietzing
city: Wien
country: Austria
facility: Wiener Gesundheitsverbund - Klinik Floridsdorf
city: Yvoir
country: Belgium
facility: CHU UCL Namur - Mont-Godinne
state: Namur
city: Antwerpen
country: Belgium
facility: Local Institution - 0014
state: VAN
city: Brussels
country: Belgium
facility: Cliniques Universitaires Saint-Luc
city: Kortrijk
country: Belgium
facility: Vzw Az Groeninge
city: Leuven
country: Belgium
facility: Local Institution - 0038
city: Liège
country: Belgium
facility: Centre Hospitalier Universitaire de Liège - Sart Tilman
city: Belo Horizonte
country: Brazil
facility: Hospital das Clínicas da Universidade Federal de Minas Gerais (UFMG)
state: Minas Gerais
city: Belo Horizonte
country: Brazil
facility: Hospital Madre Teresa
state: Minas Gerais
city: Barra Mansa
country: Brazil
facility: Centro Medico Santa Maria
state: Rio De Janeiro
city: Porto Alegre
country: Brazil
facility: WM Clinica Pneumologica Sociedade Simples LTDA
state: RIO Grande DO SUL
city: Rio De Janeiro
country: Brazil
facility: Policlínica Piquet Carneiro, Universidade do Estado do Rio de Janeiro
state: RJ
city: Porto Alegre
country: Brazil
facility: Santa Casa de Misericórdia de Porto Alegre - Hospital Sao Jose
state: RS
city: Porto Alegre
country: Brazil
facility: Hospital Ernesto Dornelles (HED)
state: RS
city: Blumenau
country: Brazil
facility: Hospital Dia do Pulmão
state: SC
city: Santo André
country: Brazil
facility: Centro de Estudos de Pneumologia da Faculdade de Medicina do ABC (CEPFMABC)
state: SP
city: São Bernardo Do Campo
country: Brazil
facility: CEMEC - Centro Multidisciplinar de Estudos Clínicos
state: SP
city: São Paulo
country: Brazil
facility: Local Institution - 0024
state: SP
city: Sao Paulo
country: Brazil
facility: Hospital Alemao Oswaldo Cruz (HAOC) - Centro de Oncologia (Oncology Center)
city: Edmonton
country: Canada
facility: Local Institution - 0208
state: Alberta
city: Sherwood Park
country: Canada
facility: Synergy Respiratory & Cardiac Care
state: Alberta
city: Kelowna
country: Canada
facility: Local Institution - 0100
state: British Columbia
city: Vancouver
country: Canada
facility: The Lung Centre
state: British Columbia
city: Vancouver
country: Canada
facility: St. Paul's Hospital
state: British Columbia
city: Burlington
country: Canada
facility: Burlington Lung Clinic
state: Ontario
city: Hamilton
country: Canada
facility: St. Joseph's Healthcare Hamilton
state: Ontario
city: Owen Sound
country: Canada
facility: Brightshores Health System
state: Ontario
city: Toronto
country: Canada
facility: Inspiration Research
state: Ontario
city: Greenfield Park
country: Canada
facility: Monteregie Centre de Recherche
state: Quebec
city: Montreal
country: Canada
facility: Centre Hospitalier de l'Université de Montréal (CHUM)
state: Quebec
city: Saint-Charles-Borromee
country: Canada
facility: C.I.C. Joliette
state: Quebec
city: Sherbrooke
country: Canada
facility: Local Institution - 0217
state: Quebec
city: Trois-Rivieres
country: Canada
facility: C.I.C. Mauricie Inc.
state: Quebec
city: Trois-Rivieres
country: Canada
facility: Diex Recherche - Trois-Rivieres
state: Quebec
city: Quebec
country: Canada
facility: Quebec Heart and Lung Institute
city: Concepcion
country: Chile
facility: Local Institution - 0503
state: Bio Bio
city: Talcahuano
country: Chile
facility: Local Institution - 0212
state: BI
city: Curico
country: Chile
facility: Centro de Investigacion Curico
state: Maule
city: Talca
country: Chile
facility: Centro de Investigación del Maule
state: Maule
city: Providencia
country: Chile
facility: Local Institution - 0080
state: RM
city: Santiago
country: Chile
facility: Clínica Universidad de los Andes
state: RM
city: Santiago
country: Chile
facility: CEC Centros Estudios Clinicos
state: RM
city: Quillota
country: Chile
facility: CENRESIN - Centro Respiratorio Integral
state: Valparaiso
city: Hefei
country: China
facility: Anhui Provincial Hospital
state: AH
city: Hefei
country: China
facility: Anhui Medical University - Anhui Chest Hospital
state: AH
city: Hefei
country: China
facility: Anhui Medical University - The Second Hospital - Hematological Research Center
state: Anhui
city: Beijing
country: China
facility: Beijing Chaoyang Hospital, Capital Medical University
state: Beijing
city: Beijing
country: China
facility: Beijing Friendship Hospital, Capital Medical University
state: Beijing
city: Beijing
country: China
facility: Peking Union Medical College Hospital
state: Beijing
city: Guangzhou Shi
country: China
facility: The First Affiliated Hospital of Guangzhou Medical University
state: Guangdong
city: Guangzhou
country: China
facility: Nanfang Hospital of Southern Medical University
state: Guangdong
city: Shenzhen Shi
country: China
facility: Shenzhen People's Hospital
state: Guangdong
city: Shenzhen
country: China
facility: Peking University Shenzhen Hospital
state: Guangdong
city: Zhengzhou
country: China
facility: Henan Provincial People's Hospital
state: Hainan
city: Zhengzhou
country: China
facility: The First Affiliated Hospital of Zhengzhou University
state: Hainan
city: Shijiazhuang
country: China
facility: The Second Hospital of Hebei Medical University
state: Hebei
city: Yichang Shi
country: China
facility: Yichang Central People's Hospital - Xiling Campus
state: Hebei
city: Zhengzhou Shi
country: China
facility: Local Institution - 0296
state: Henan
city: Wuhan
country: China
facility: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
state: Hubei
city: Wuhan
country: China
facility: Renmin Hospital of Wuhan University
state: HUB
city: Suzhou Shi
country: China
facility: The First Affiliated Hospital of Soochow University
state: Jiangsu
city: Wuxi
country: China
facility: Wuxi People's Hospital
state: Jiangsu
city: Xuzhou
country: China
facility: The Affiliated Hospital of Xuzhou Medical University
state: Jiangsu
city: Nanchang
country: China
facility: The First Affiliated Hospital of Nanchang University - Xianghu District
state: Jiangxi
city: Shenyang
country: China
facility: The First Hospital of China Medical University
state: Liaoning
city: Shenyang
country: China
facility: Shengjing Hospital of China Medical University
state: Liaoning
city: Shenyang
country: China
facility: Shenyang Chest Hospital
state: Liaoning
city: Shanghai
country: China
facility: Shanghai Jiao Tong University - Shanghai Chest Hospital
state: Shanghai
city: Shanghai
country: China
facility: Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine - South Branch
state: Shanghai
city: Chengdu
country: China
facility: West China Hospital, Sichuan University
state: Sichuan
city: Tianjin
country: China
facility: Tianjin Medical University General Hospital
state: Tianjin
city: Tianjin
country: China
facility: Tianjin Chest Hospital
state: Tianjin
city: Hangzhou Shi
country: China
facility: The Second Affiliated Hospital of Zhejiang University School of Medicine
state: Zhejiang
city: Hangzhou
country: China
facility: Local Institution - 0223
state: Zhejiang
city: Hangzhou
country: China
facility: Hangzhou First People's Hospital
state: Zhejiang
city: Ningbo
country: China
facility: The First Affiliated Hospital of Ningbo University
state: Zhejiang
city: Changsha
country: China
facility: The Second Xiangya Hospital of Central South University
city: Changsha
country: China
facility: Local Institution - 0448
city: Chengdu Shi
country: China
facility: Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital
city: Guangzhou Shi
country: China
facility: The First Affiliated Hospital, Sun Yat-sen University
city: Hohhot
country: China
facility: The Affiliated Hospital of Inner Mongolia Medical University
city: Jinan Shi
country: China
facility: Qilu Hospital of Shandong University
city: Nanjing
country: China
facility: Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
city: Shanghai
country: China
facility: Huadong Hospital Affiliated to Fudan University
city: Shanghai
country: China
facility: Shanghai Jiaotong University Affiliated Sixth People's Hospital
city: Shanghai
country: China
facility: Shanghai Pulmonary Hospital
city: Shijiazhuang
country: China
facility: The Third Hospital of Hebei Medical University
city: Xi'an
country: China
facility: Xi'an International Medical Center Hospital
city: Yinchuan
country: China
facility: Local Institution - 0376
city: Medellin
country: Colombia
facility: Servicios de Salud IPS Suramericana S.A.S - IPS Sura Industriales Medellín
state: ANT
city: Bogota
country: Colombia
facility: Health SURA Calle 100
state: DC
city: Floridablanca
country: Colombia
facility: Instituto Neumologico del Oriente
state: Santander
city: Santiago De Cali
country: Colombia
facility: Health SURA Chipichape
state: VAC
city: Bogota
country: Colombia
facility: Fundacion Santa Fe de Bogota
city: Manizales
country: Colombia
facility: Medicos Internistas de Caldas
city: Brno
country: Czechia
facility: Local Institution - 0063
state: JM
city: Olomouc
country: Czechia
facility: Local Institution - 0340
city: Prague
country: Czechia
facility: Local Institution - 0087
city: Aarhus
country: Denmark
facility: Aarhus University Hospital
state: Region Midtjylland
city: Odense C
country: Denmark
facility: Odense Universitetshospital - Svendborg Sygehus
state: Region Syddanmark
city: Hellerup
country: Denmark
facility: Gentofte Hospital
city: Turku
country: Finland
facility: Turun Yliopistollinen Keskussairaala (TYKS)
state: Laensi-Suomen Laeaeni
city: Helsinki
country: Finland
facility: Helsinki University Hospital Heart and Lung Center
city: Bron
country: France
facility: Hospices Civils De Lyon
state: Auvergne-Rhône-Alpes
city: Grenoble
country: France
facility: Centre Hospitalier Universitaire Grenoble Alpes (CHU Grenoble Alpes)
state: Auvergne-Rhône-Alpes
city: Nantes Cedex 01
country: France
facility: CHU de Nantes - Hôpital Nord Laennec
state: Pays De La Loire
city: Marseille
country: France
facility: Assistance Publique Hopitaux de Marseille - Hopital Nord
state: Provence-Alpes-Côte d'Azur
city: Angers
country: France
facility: Centre Hospitalier Universitaire d'Angers
city: Bobigny
country: France
facility: Hôpital Avicenne
city: Brest
country: France
facility: CHU de Brest - Hôpital Cavale Blanche
city: Dijon
country: France
facility: CHU Dijon - Hôpital François Mitterrand
city: Lille CEDEX
country: France
facility: Local Institution - 0311
city: Nice
country: France
facility: Local Institution - 0091
city: Paris
country: France
facility: Local Institution - 0308
city: Paris
country: France
facility: Hôpital Bichat - Claude-Bernard
city: Pessac
country: France
facility: CHU Hopitaux de Bordeaux - Hopital Haut-Leveque
city: Rennes
country: France
facility: Local Institution - 0081
city: Toulouse
country: France
facility: Hôpital Larrey
city: Tours
country: France
facility: CHRU de Tours - Hôpital Bretonneau
city: Munich
country: Germany
facility: Klinikum der Universität München
state: Bavaria
city: Berlin
country: Germany
facility: Vivantes Klinikum Neukölln
state: BE
city: Berlin
country: Germany
facility: HELIOS Klinikum Emil von Behring
state: BE
city: Freiburg I. Breisgau
country: Germany
facility: Universitaetsklinikum Freiburg - Klinik fuer Pneumologie
state: BW
city: Stuttgart
country: Germany
facility: Robert-Bosch-Krankenhaus
state: BW
city: Wangen I. Allgaeu
country: Germany
facility: Local Institution - 0006
state: BW
city: Munnerstadt
country: Germany
facility: Thoraxzentrum Bezirk Unterfranken
state: BY
city: Immenhausen
country: Germany
facility: Lungenfachklinik Immenhausen
state: HE
city: Marburg
country: Germany
facility: Praxis fur Pneumologie
state: HE
city: Hamburg
country: Germany
facility: Universitätsklinikum Hamburg-Eppendorf (UKE)
state: HH
city: Essen
country: Germany
facility: Universitaetsklinikum Essen - Ruhrlandklinik
state: Nordrhein Westfalen
city: Cologne
country: Germany
facility: Krankenhaus der Augustinerinnen- Klinik fuer Pneumologie, Allergologie, Schlaf- und Beatmungsmedizin
state: Northwest
city: Munster
country: Germany
facility: Local Institution - 0008
state: Northwest
city: Ahrensburg
country: Germany
facility: Velocity Clinical Research Germany GmbH
city: Coswig
country: Germany
facility: Fachkrankenhaus Coswig GmbH
city: Heidelberg
country: Germany
facility: Thoraxklinik-Heidelberg gGmbH
city: Leipzig
country: Germany
facility: Universitaetsklinikum Leipzig - Klinik und Poliklinik fuer Pneumologie
city: Mainz
country: Germany
facility: Universitätsmedizin der Johannes Gutenberg-Universität Mainz
city: Maroussi
country: Greece
facility: Athens Medical Center
state: Attica
city: Pylaia-Chortiatis
country: Greece
facility: General Hospital of Thessaloniki "G. Papanikolaou"
state: B
city: Ioannina
country: Greece
facility: Local Institution - 0104
state: Epirus
city: Heraklion
country: Greece
facility: Local Institution - 0450
state: Iraklio Kritis
city: Pilea Chortiatis
country: Greece
facility: Local Institution - 0454
state: Thessaloniki
city: Athens
country: Greece
facility: University General Hospital Attikon
city: Corfu
country: Greece
facility: Corfu General Hospital "St. IRINI"
city: Larisa
country: Greece
facility: University of Thessaly- General University Hospital of Larissa
city: Rio
country: Greece
facility: University of Patras - Rio Regional University Hospital
city: Budapest
country: Hungary
facility: Pulmonologiai Klinika
city: Gyor
country: Hungary
facility: Petz Aladár Megyei Oktató Kórház
city: New Delhi
country: India
facility: Local Institution - 0285
state: Delhi
city: New Delhi
country: India
facility: All India Institute of Medical Sciences (AIIMS) - New Delhi
state: DL
city: Surat
country: India
facility: Unity Hospital
state: GJ
city: Ahmedabad
country: India
facility: Local Institution - 0427
state: Gujarat
city: Ahmedabad
country: India
facility: Marengo CIMS Hospital
state: Gujarat
city: Vadodara
country: India
facility: Local Institution - 0475
state: Gujarat
city: Belagavi
country: India
facility: K.L.E.S. Dr. Prabhakar Kore Hospital & Medical Research Centre
state: KA
city: Pune
country: India
facility: Jehangir Clinical Development Center
state: Maharashtra
city: Nagpur
country: India
facility: Shree Hospital and Critical Care Centre
state: MH
city: Nagpur
country: India
facility: Local Institution - 0245
state: MH
city: Nagpur
country: India
facility: Getwell Hospital and Research Institute - Lungs Care
state: MH
city: Pune
country: India
facility: Grant Medical Foundation - Ruby Hall Clinic
state: MH
city: Pune
country: India
facility: ACE Hospital & Research Center
state: MH
city: Pune
country: India
facility: Local Institution - 0280
state: MH
city: Bhopal
country: India
facility: Green City Hospital
state: MP
city: Mohali
country: India
facility: Fortis Hospital Mohali
state: Punjab
city: Jaipur
country: India
facility: Local Institution - 0281
state: RJ
city: Jaipur
country: India
facility: Asthma Bhawan
state: RJ
city: Jaipur
country: India
facility: Local Institution - 0499
state: RJ
city: Hyderabad
country: India
facility: Local Institution - 0500
state: TG
city: Noida
country: India
facility: Local Institution - 0381
state: UP
city: Lucknow
country: India
facility: Local Institution - 0477
state: Uttar Pradesh
city: Dehradun
country: India
facility: Shri Guru Ram Rai (SGRR) Institute of Medical and Health Sciences - Shri Mahant Indiresh Hospital
state: UT
city: Kolkata
country: India
facility: Nilratan Sircar (NRS) Medical College & Hospital
state: WB
city: Bangalore
country: India
facility: St. John's Medical College
city: Lucknow
country: India
facility: Midland Healthcare & Research Center
city: Drogheda
country: Ireland
facility: Our Lady of Lourdes Hospital - Drogheda
state: LH
city: Dublin 4
country: Ireland
facility: St. Vincent's University Hospital
city: Dublin
country: Ireland
facility: Connolly Hospital Blanchardstown
city: Haifa
country: Israel
facility: Carmel Medical Center
state: HA
city: Be'er Sheva
country: Israel
facility: Local Institution - 0445
city: Haifa
country: Israel
facility: Rambam Health Care Campus - Pulmonology
city: Jerusalem
country: Israel
facility: Hadassah Medical Center (HMC) - Hadassah University Hospital (HUH) - Ein Kerem
city: Petah-Tikva
country: Israel
facility: Rabin Medical Center - Hasharon Hospital
city: Rehovot
country: Israel
facility: Kaplan Medical Center
city: Tel Aviv-Yafo
country: Israel
facility: Tel Aviv Sourasky Medical Center
city: Bologna
country: Italy
facility: Local Institution - 0329
state: BO
city: Modena
country: Italy
facility: Azienda Ospedaliero - Universitaria di Modena Policlinico
state: Emilia-Romagna
city: Firenze
country: Italy
facility: Azienda Ospedaliero-Universitaria Careggi
state: FI
city: Milano
country: Italy
facility: Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
state: MI
city: Milano
country: Italy
facility: Local Institution - 0310
state: MI
city: Milano
country: Italy
facility: Local Institution - 0133
state: MI
city: Pisa
country: Italy
facility: Azienda Ospedaliero Universitaria Pisana
state: PI
city: Roma
country: Italy
facility: Fondazione Policlinico Universitario Agostino Gemelli
state: RM
city: Trieste
country: Italy
facility: Local Institution - 0115
state: TS
city: Ancona
country: Italy
facility: Azienda Ospedaliero Universitaria delle Marche
city: Bergamo
country: Italy
facility: ASST Papa Giovanni XXIII
city: Foggia
country: Italy
facility: Ospedale Colonnello D'Avanzo Foggia
city: Forli
country: Italy
facility: Ospedale "Gian Battista Morgagni - Luigi Pierantoni" di Forli
city: Milan
country: Italy
facility: Azienda Ospedaliera San Paolo
city: Monza
country: Italy
facility: Fondazione IRCCS San Gerardo dei Tintori
city: Naples
country: Italy
facility: Local Institution - 0116
city: Napoli
country: Italy
facility: AORN - Ospedali dei Colli Ospedale V. Monaldi
city: Palermo
country: Italy
facility: Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (ISMETT)
city: Pavia
country: Italy
facility: Fondazione IRCCS Policlinico San Matteo
city: Sassari
country: Italy
facility: Azienda Ospedaliera Universitaria - Universita di Sassari
city: Siena
country: Italy
facility: Ospedale Policlinico di Siena
city: Chiba-Shi
country: Japan
facility: Chiba University Hospital
state: Chiba
city: Kitakyushu-shi
country: Japan
facility: Local Institution - 0317
state: Fukuoka-Ken
city: Fukuoka-Shi
country: Japan
facility: National Hospital Organization Kyushu Medical Center
state: Fukuoka
city: Fukuoka-shi
country: Japan
facility: Kyushu University Hospital
state: Fukuoka
city: Koriyama-shi
country: Japan
facility: Jizankai Medical Foundation Tsuboi Cancer Center Hospital
state: Fukushima
city: Naka-gun
country: Japan
facility: National Hospital Organization Ibarakihigashi National Hospital
state: Gunma
city: Hiroshima-shi
country: Japan
facility: Hiroshima Prefectural Hospital
state: Hirohima-ken
city: Sapporo
country: Japan
facility: Sapporo Medical University Hospital
state: Hokkaido
city: Kobe
country: Japan
facility: Kobe City Medical Center General Hospital
state: Hyogo
city: Matsusaka-shi
country: Japan
facility: Matsusaka Municipal Hospital
state: Mie
city: Nagasaki-shi
country: Japan
facility: Nagasaki University Hospital
state: NGS
city: Ginowan-Shi
country: Japan
facility: National Hospital Organization - Okinawa National Hospital
state: Okinawa
city: Osakasayama-shi
country: Japan
facility: Kindai University Hospital
state: Osaka
city: Sakai City
country: Japan
facility: National Hospital Organization Kinki-chuo Chest Medical Center
state: OSK
city: Bunkyo-Ku
country: Japan
facility: Juntendo University Hospital
state: TKY
city: Shimotsuge-shi
country: Japan
facility: Jichi Medical University Hospital
state: Tochigi
city: Tokushima-Shi
country: Japan
facility: Local Institution - 0070
state: Tokushima
city: Bunkyo-Ku
country: Japan
facility: Institute of Science Tokyo Hospital
state: Tokyo
city: Bunkyo-ku
country: Japan
facility: Nippon Medical School Hospital
state: Tokyo
city: Mitaka-shi
country: Japan
facility: Kyorin University Hospital
state: Tokyo
city: Shinjuku-Ku
country: Japan
facility: Tokyo Medical University Hospital
state: Tokyo
city: Fukuoka
country: Japan
facility: Kurume University Hospital
city: Hamamatsu-shi
country: Japan
facility: Hamamatsu University Hospital
city: Himeji-Shi
country: Japan
facility: Himeji Medical Center
city: Iizuka-shi
country: Japan
facility: Aso Iizuka Hospital
city: Izumo-Shi
country: Japan
facility: Shimane University Hospital
city: Kamogawa-Shi
country: Japan
facility: Kameda Medical Center - Kameda Clinic
city: Kumamoto-Shi
country: Japan
facility: Saiseikai Kumamoto Hospital
city: Minato-Ku
country: Japan
facility: Toranomon Hospital
city: Minato-ku
country: Japan
facility: The Jikei University Hospital
city: Nagoya
country: Japan
facility: Nagoya University Hospital
city: Seto
country: Japan
facility: Tosei General Hospital
city: Shinjyu-Ku
country: Japan
facility: Center Hospital of the National Center for Global Health and Medicine
city: Tenri-Shi
country: Japan
facility: Tenri Hospital
city: Tokyo
country: Japan
facility: Toho University - Omori Medical Center
city: Uruma-shi
country: Japan
facility: Local Institution - 0303
city: Yokohama-Shi
country: Japan
facility: Kanagawa Cardiovascular and Respiratory Center
city: Yoshida-Gun
country: Japan
facility: University of Fukui Hospital
city: Goyang-si
country: Korea, Republic of
facility: Inje University Ilsan Paik Hospital
state: Gyeonggi-Do
city: Goyang-si
country: Korea, Republic of
facility: Myongji Hospital
state: Gyeonggi
city: Jongno-gu
country: Korea, Republic of
facility: Seoul National University Hospital
state: Seoul
city: Yongsan-gu
country: Korea, Republic of
facility: SoonChunHyang University Seoul Hospital
state: Seoul
city: Dong-gu
country: Korea, Republic of
facility: Ulsan University Hospital (UUH)
state: Ulsan
city: Bucheon-Si
country: Korea, Republic of
facility: SoonChunHyang University Bucheon Hospital
city: Bucheonsi Weonmigu
country: Korea, Republic of
facility: The Catholic University of Korea, Bucheon St. Mary's Hospital
city: Busan
country: Korea, Republic of
facility: Inje University Busan Paik Hospital
city: Deogyang-Gu, Goyang-Si
country: Korea, Republic of
facility: Local Institution - 0316
city: Dong-Gu
country: Korea, Republic of
facility: University of Ulsan College of Medicine - Ulsan University Hospital (UUH)
city: Gyeonggi-do
country: Korea, Republic of
facility: Seoul National University Bundang Hospital
city: Haeundae-Gu
country: Korea, Republic of
facility: Inje University Haeundae Paik Hospital
city: Iksansi
country: Korea, Republic of
facility: Wonkwang University Hospital
city: Incheon
country: Korea, Republic of
facility: Gachon University - Gil Medical Center
city: Incheon
country: Korea, Republic of
facility: Local Institution - 0312
city: Seoul
country: Korea, Republic of
facility: Yonsei University Health System, Severance Hospital
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center (AMC)
city: Seoul
country: Korea, Republic of
facility: Local Institution - 0397
city: Suwon, Gyeonggi-do
country: Korea, Republic of
facility: Ajou University Hospital
city: Kajang
country: Malaysia
facility: Local Institution - 0465
state: Selangor Darul Ehsan
city: Kuala Lumpur
country: Malaysia
facility: Local Institution - 0467
state: Wilayah Persekutuan Kuala Lumpur
city: Kuching
country: Malaysia
facility: Local Institution - 0466
city: Aguascalientes
country: Mexico
facility: Local Institution - 0141
state: AGU
city: Magdalena Contreras
country: Mexico
facility: Local Institution - 0219
state: Cdmx
city: Chihuahua
country: Mexico
facility: Local Institution - 0476
state: CHH
city: Metepec
country: Mexico
facility: Instituto de Seguridad Social del Estado de Mexico y Municipios (ISSEMYM) - Centro Medico Toluca
state: Edo De Mexico
city: Guadalajara
country: Mexico
facility: Local Institution - 0494
state: Jalisco
city: Guadalajara
country: Mexico
facility: Local Institution - 0136
state: JAL
city: Guadalajara
country: Mexico
facility: Local Institution - 0248
state: JAL
city: Morelia
country: Mexico
facility: Centro de Investigación Clínica Chapultepec S.A. de C.V.
state: MIC
city: Monterrey
country: Mexico
facility: Local Institution - 0162
state: Nuevo Leon
city: Oaxaca
country: Mexico
facility: Local Institution - 0422
state: OAX
city: Oaxaca
country: Mexico
facility: Centro de Investigacion Clinica de Oaxaca (CICLO)
state: OAX
city: Córdoba
country: Mexico
facility: Local Institution - 0163
state: VER
city: Mérida
country: Mexico
facility: Local Institution - 0234
state: YUC
city: Chihuahua
country: Mexico
facility: Local Institution - 0277
city: Guadalajara
country: Mexico
facility: Local Institution - 0413
city: Mexico City
country: Mexico
facility: Local Institution - 0001
city: Rotterdam
country: Netherlands
facility: Erasmus MC - Centrum voor Interstitiele Longziekten
state: South Holland
city: 's-Gravenhage
country: Netherlands
facility: Local Institution - 0032
state: ZH
city: Amsterdam
country: Netherlands
facility: Amsterdam UMC - Locatie VUMC - Pulmonale Hypertensie (PH) Kenniscentrum
city: Amsterdam
country: Netherlands
facility: Local Institution - 0423
city: Heerlen
country: Netherlands
facility: Zuyderland Medisch Centrum, Sittard-Geleen
city: Nieuwegein
country: Netherlands
facility: St. Antonius Ziekenhuis
city: Lima
country: Peru
facility: Local Institution - 0016
state: LIM
city: Lima
country: Peru
facility: Local Institution - 0220
state: LIM
city: Lima
country: Peru
facility: Local Institution - 0399
state: LIM
city: San Miguel
country: Peru
facility: Local Institution - 0144
state: LIM
city: Piura
country: Peru
facility: Local Institution - 0156
state: PIU
city: Lima
country: Peru
facility: Local Institution - 0055
city: Lima
country: Peru
facility: Hospital Nacional Cayetano Heredia
city: Bydgoszcz
country: Poland
facility: MICS Centrum Medyczne Bydgoszcz
state: KP
city: Bydgoszcz
country: Poland
facility: NZOZ Przychodnia Vitamed
state: KP
city: Kraków
country: Poland
facility: Local Institution - 0327
state: MA
city: Bialystok
country: Poland
facility: Centrum Medycyny Oddechowej
state: PD
city: Gdansk
country: Poland
facility: Uniwersyteckie Centrum Kliniczne
state: Pomorskie
city: Olsztyn
country: Poland
facility: Warminsko-Mazurskie Centrum Chorób Pluc w Olsztynie
state: WN
city: Bedzin
country: Poland
facility: Local Institution - 0076
city: Katowice
country: Poland
facility: Local Institution - 0148
city: Lodz
country: Poland
facility: Uniwersytecki Szpital Kliniczny Nr. 1 im. Norberta Barlickiego
city: Braga
country: Portugal
facility: Local Institution - 0453
city: Faro
country: Portugal
facility: Unidade Local de Saúde do Algarve, EPE
city: Lisboa
country: Portugal
facility: Hospital de Santa Marta
city: Lisboa
country: Portugal
facility: Hospital CUF Tejo
city: Lisboa
country: Portugal
facility: Unidade Local de Saude de Santa Maria, EPE - Hospital Pulido Valente
city: Loures
country: Portugal
facility: Unidade Local de Saude de Loures - Odivelas, E. P. E.
city: Porto
country: Portugal
facility: Unidade Local de Saude de Santo Antonio, E.P.E.
city: Porto
country: Portugal
facility: Unidade Local de Saude de Sao Joao, EPE - Hospital de Sao Joao
city: Vila Nova de Gaia
country: Portugal
facility: Unidade Local de Saude de Gaia/Espinho, EPE
city: Guaynabo
country: Puerto Rico
facility: Alliance Pulmonary Group
city: Guaynabo
country: Puerto Rico
facility: Local Institution - 0444
city: Badalona
country: Spain
facility: Local Institution - 0020
state: Barcelona
city: Santander
country: Spain
facility: Hospital Universitario Marqués de Valdecilla
state: CB
city: Valencia
country: Spain
facility: Local Institution - 0157
state: Comunidad Valencia
city: Santiago de Compostela
country: Spain
facility: Santiago Clinic Hospital (Hospital Clínico Universitario de Santiago -CHUS)
state: C
city: Madrid
country: Spain
facility: Hospital Universitario de la Princesa
state: M
city: Madrid
country: Spain
facility: Hospital Clínico San Carlos
state: M
city: Madrid
country: Spain
facility: Hospital Universitario La Paz
state: M
city: Majadahonda
country: Spain
facility: Hospital Universitario Puerta de Hierro - Majadahonda
state: M
city: Barcelona
country: Spain
facility: Hospital Clínic de Barcelona
city: Barcelona
country: Spain
facility: Hospital Universitari de Bellvitge (IDIBELL)
city: Girona
country: Spain
facility: Giromed Institute, SLP
city: Madrid
country: Spain
facility: Clínica Universidad de Navarra -Madrid
city: Madrid
country: Spain
facility: Hospital Universitario Fundacion Jimenez Diaz
city: Madrid
country: Spain
facility: Hospital Clinico Universitario
city: Oviedo
country: Spain
facility: Hospital Universitario Central de Asturias
city: Pamplona
country: Spain
facility: Clínica Universidad de Navarra
city: Bern
country: Switzerland
facility: Inselspital - Universitaetsklinik Bern für Pneumologie
state: BE
city: Basel
country: Switzerland
facility: Universitätsspital Basel
state: BS
city: Genève
country: Switzerland
facility: Hopitaux Universitaires de Geneve (HUG)
state: Geneve
city: St Gallen
country: Switzerland
facility: Local Institution - 0462
city: Changhua
country: Taiwan
facility: Changhua Christian Hospital
state: CHA
city: Kaohsiung
country: Taiwan
facility: Chang Gung Medical Foundation - Kaohsiung Branch
state: Kao-Hsiung
city: Taichung
country: Taiwan
facility: China Medical University Hospital
state: TXG
city: Douliu Shi
country: Taiwan
facility: National Taiwan University Hospital Yun-Lin Branch
state: YUN
city: Kaohsiung
country: Taiwan
facility: Kaohsiung Medical University Chung-Ho Memorial Hospital
city: New Taipei City
country: Taiwan
facility: Far Eastern Memorial Hospital
city: Taichung
country: Taiwan
facility: Taichung Veterans General Hospital
city: Taipei City
country: Taiwan
facility: Taipei Veterans General Hospital
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital - The National Center of Excellence for Clinical Trial
city: Bangkok-Noi
country: Thailand
facility: Local Institution - 0463
state: Bangkok
city: Mueang Chiang Mai
country: Thailand
facility: Local Institution - 0468
state: Chiang Mai
city: Muang Khon Kaen
country: Thailand
facility: Local Institution - 0471
state: Khon Kaen
city: Hatyai
country: Thailand
facility: Local Institution - 0469
state: Songkla
city: Bangkok
country: Thailand
facility: Local Institution - 0464
city: Adana
country: Turkey
facility: Local Institution - 0071
city: Ankara
country: Turkey
facility: Ankara Universitesi Tip Fakultesi Hastaneleri - Cebeci Hastanesi
city: Bursa
country: Turkey
facility: Uludag Universitesi Tip Fakultesi (Uludag University Faculty of Medicine)
city: Guemueshane
country: Turkey
facility: Erciyes University School of Medicine
city: Izmir
country: Turkey
facility: Ege Universitesi Tip Fakultesi Hastanesi (Ege University Medical Faculty Hospital)
city: Izmir
country: Turkey
facility: TC Saglik Bakanlig -Izmir Dr.Suat Seren Gogus Hastaliklari Ve Cerrahisi Egitim Arastirma Hastanesi
city: Keçiören/Ankara
country: Turkey
facility: Local Institution - 0451
city: Maltepe
country: Turkey
facility: T.C.S.B. Süreyyapasa Gögüs Hastaliklari Egitim Ve Arastirma Hastanesi
city: Pasaport
country: Turkey
facility: Dokuz Eylul Universitesi Tip Fakultesi
city: Topkapı
country: Turkey
facility: Istanbul Universitesi - Istanbul Tip Fakultesi (ITF) Hastanesi
city: Birmingham
country: United Kingdom
facility: University Hospitals Birmingham NHS Foundation Trust - Heartlands Hospital
state: BIR
city: Bristol
country: United Kingdom
facility: North Bristol NHS Trust - Southmead Hospital Bristol
state: BST
city: Cambridge
country: United Kingdom
facility: Papworth Hospital NHS Foundation Trust
state: Cambridgeshire
city: Dundee
country: United Kingdom
facility: NHS Tayside
state: DND
city: Edinburgh
country: United Kingdom
facility: NHS Lothian - Royal Infirmary of Edinburgh
state: EDH
city: London
country: United Kingdom
facility: Guy's and St Thomas' NHS Foundation Trust - Royal Brompton Hospital
state: Greater London
city: Southampton
country: United Kingdom
facility: Local Institution - 0392
state: Hampshire
city: Nottingham
country: United Kingdom
facility: Local Institution - 0432
state: Nottinghamshire
city: Oxford
country: United Kingdom
facility: Oxford University Hospitals NHS Trust - Churchill Hospital
state: Oxfordshire
city: Peterborough
country: United Kingdom
facility: Peterborough City Hospital
state: PTE
city: Exeter
country: United Kingdom
facility: Local Institution - 0203
state: South West
city: South Shields
country: United Kingdom
facility: Local Institution - 0447
state: STY
city: Cottingham
country: United Kingdom
facility: Hull and East Yorkshire Hospitals NHS Trust - Castle Hill Hospital
state: Yorkshire And The Humber
city: Birmingham
country: United Kingdom
facility: University Hospitals Birmingham NHS Foundation Trust - New Queen Elizabeth Hospital Birmingham
city: Leeds
country: United Kingdom
facility: Leeds Teaching Hospitals NHS Trust
Study officials:
affiliation: Bristol-Myers Squibb
name: Bristol-Myers Squibb
role: STUDY_DIRECTOR
References: