Clinical trial NCT06975566: Long-term Effects of Radial Artery Cannulation on Vessel Diameter, Blood Flow and Fine Motor Skills
Official title: Long-term Effects of Radial Artery Cannulation on Vessel Diameter, Blood Flow and Fine Motor Skills
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Radial Artery
Ultrasound
Fine Motor Skills
Keywords: Catheterization
Regional blood flow
Fine motor skills
Lead sponsor: Kartal City Hospital
Sponsor class: OTHER
First posted: 2025-05-16
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: patients undergoing surgical intervention at Pamukkale University Faculty of Medicine, Department of Cardiovascular Surgery, between June and September 2016. Patients aged 18 to 80 years, scheduled for elective surgery, and with an indication for radial artery cannulation were included in the study.

Brief summary: The present study aims to investigate hemodynamic changes in radial and ulnar artery blood flow following radial artery cannulation performed in elective surgical cases under operating room conditions using Doppler ultrasonography. Additionally, it aims to evaluate the long-term impact of this procedure on vascular flow parameters and fine motor function.

Detailed description: This prospective self controlled study included 50 patients aged 18-80 years with an ASA physical status of 1-3 who required arterial cannulation for planned surgical procedures in the cardiovascular surgery operating rooms of Pamukkale University Faculty of Medicine. Before the procedure, radial and ulnar artery Doppler parameters (peak systolic velocity, end-diastolic velocity, resistance index, pulsatility index, and mean volume flow) were measured for all patients, along with Purdue Pegboard scores for fine motor skill assessment. Post-cannulation Doppler parameters were evaluated at seven different time points over three months, while fine motor skill scores were measured twice more during follow-up.

Eligibility criteria: Inclusion Criteria:

indication for radial artery cannulation

Exclusion Criteria:

emergency surgery inadequate collateral blood flow

Primary outcomes:
measure: 90 DAY FOLLOW-UP PERIOD
timeFrame: From the first measurement before cannulation to the last measurement after 90 days
measure: 90 DAY FOLLOW-UP PERIOD
timeFrame: From the first measurement before cannulation to the last measurement after 90 days
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Desrosiers J, Hebert R, Bravo G, Rochette A. Age-related changes in upper extremity performance of elderly people: a longitudinal study. Exp Gerontol. 1999 Jun;34(3):393-405. doi: 10.1016/s0531-5565(99)00018-2.
citation: Taneja K, Jain R, Sawhney S, Rajani M. Occlusive arterial disease of the upper extremity: colour Doppler as a screening technique and for assessment of distal circulation. Australas Radiol. 1996 Aug;40(3):226-9. doi: 10.1111/j.1440-1673.1996.tb00391.x.
citation: Numaguchi A, Adachi YU, Aoki Y, Ishii Y, Suzuki K, Obata Y, Sato S, Nishiwaki K, Matsuda N. Radial artery cannulation decreases the distal arterial blood flow measured by power Doppler ultrasound. J Clin Monit Comput. 2015 Oct;29(5):653-7. doi: 10.1007/s10877-014-9648-5. Epub 2014 Dec 16.