Clinical trial NCT03786380: Diabetic Gastroparesis Study 05
Official title: Open-label Extension Study of Relamorelin for the Treatment of Diabetic Gastroparesis
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: PHASE3
Conditions: Gastroparesis
Keywords: Diabetic Gastroparesis
Lead sponsor: Allergan
Sponsor class: INDUSTRY
First posted: 2018-12-26
Enrollment: 202
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This open-label study is to assess the safety of continued treatment with relamorelin for participants who previously completed the RLM-MD-03 \[NCT03420781\] or RLM-MD-04 \[NCT03383146\] study and to provide treatment for these participants until relamorelin becomes commercially available or the Sponsor terminates development.


Eligibility criteria: Inclusion Criteria:

* Successful completion of either Study RLM-MD-03 or Study RLM-MD-04
* Ability to provide written informed consent (IC) prior to any study procedures and willingness and ability to comply with study procedures
* Demonstration of adequate compliance with the study procedures in Study RLM-MD-03 or RLM-MD-04, in the opinion of the investigator.

Exclusion Criteria:

* Participant is planning to receive an investigational drug (other than study intervention) or investigational device at any time during Study 3071-305-020
* Participant has an unresolved adverse event (AE) from a lead-in study, ie, a clinically significant finding on physical examination, clinical laboratory test, or 12-lead electrocardiogram (ECG) that, in the investigator's opinion, would limit the participant's ability to participate in or complete the study
* Any other reason that, in the investigator's opinion, would confound proper interpretation of the study or expose a participant to unacceptable risk, including renal, hepatic, or cardiopulmonary disease
* Females who are pregnant, nursing, or planning a pregnancy during the study.

Primary outcomes:
measure: Number of Participants Who Experienced One or More Treatment-Emergent Adverse Events (TEAEs)
timeFrame: Up to approximately 22 months
measure: Number of Participants With Potential Clinically Significant (PCS) Clinical Laboratory Results
timeFrame: Baseline (Day 1) up to approximately 22 months
measure: Number of Participants With Clinically Meaningful Trends for Vital Signs
timeFrame: Up to approximately 22 months
measure: Number of Participants With Clinically Meaningful Trends in Electrocardiogram (ECG) Results
timeFrame: Up to approximately 22 months
Secondary outcomes:
Other outcomes:
Locations:
city: Anniston
country: United States
facility: Pinnacle Research Group
state: Alabama
city: Athens
country: United States
facility: North Alabama Research Center, LLC
state: Alabama
city: Birmingham
country: United States
facility: University of Alabama at Birmingham
state: Alabama
city: Dothan
country: United States
facility: Digestive Health Specialist of the South East
state: Alabama
city: Foley
country: United States
facility: G & L Research, LLC
state: Alabama
city: Mobile
country: United States
facility: Alabama Medical Group, PC
state: Alabama
city: Chandler
country: United States
facility: Del Sol Research Management, LLC
state: Arizona
city: Phoenix
country: United States
facility: Phoenix Clinical LLC.
state: Arizona
city: Tucson
country: United States
facility: Adobe Clinical Research LLC
state: Arizona
city: Tucson
country: United States
facility: Del Sol Research Management, LLC
state: Arizona
city: Little Rock
country: United States
facility: Preferred Clinical Research Partners
state: Arkansas
city: Little Rock
country: United States
facility: Applied Research Center of Arkansas
state: Arkansas
city: North Little Rock
country: United States
facility: Arkansas Gastroenterology
state: Arkansas
city: Anaheim
country: United States
facility: HCP Clinical Research LLC
state: California
city: Canoga Park
country: United States
facility: Hope Clinical Research
state: California
city: Chula Vista
country: United States
facility: GW Research Inc
state: California
city: Corona
country: United States
facility: Kindred Medical Institute for Clinical Trials, LLC
state: California
city: Costa Mesa
country: United States
facility: Aurora Care Clinic, LLC
state: California
city: Encinitas
country: United States
facility: Diagnamics Inc.
state: California
city: Garden Grove
country: United States
facility: Valley View Wellness and Medical Center - VVCRD Clinical Research
state: California
city: La Jolla
country: United States
facility: University of California San Diego
state: California
city: Lancaster
country: United States
facility: Om Research LLC
state: California
city: Lomita
country: United States
facility: Torrance Clinical Research Institute, Inc.
state: California
city: Long Beach
country: United States
facility: Tibor Rubin VA Medical Center
state: California
city: Los Angeles
country: United States
facility: Angel City Research Inc.
state: California
city: Mission Hills
country: United States
facility: Facey Medical Foundation
state: California
city: Palo Alto
country: United States
facility: Stanford Hospital
state: California
city: Poway
country: United States
facility: TriWest Research Associates
state: California
city: San Diego
country: United States
facility: Clinical Applications Laboratories, Inc.
state: California
city: San Diego
country: United States
facility: Medical Associates Research Group, Inc
state: California
city: Santa Ana
country: United States
facility: Syrentis Clinical Research
state: California
city: Upland
country: United States
facility: Upland Clinical Research
state: California
city: Whittier
country: United States
facility: New Hope Research Development
state: California
city: Aurora
country: United States
facility: University of Colorado, Denver
state: Colorado
city: Colorado Springs
country: United States
facility: Peak Gastroenterology Associates
state: Colorado
city: Englewood
country: United States
facility: Denver Esophageal and Stomach Center
state: Colorado
city: Bridgeport
country: United States
facility: Gastroenterology Associates of Fairfield County, P.C.
state: Connecticut
city: Bristol
country: United States
facility: Connecticut Clinical Research Foundation
state: Connecticut
city: Hamden
country: United States
facility: Medical Research Center of Connecticut, LLC
state: Connecticut
city: Aventura
country: United States
facility: Visionary Investigators Network
state: Florida
city: Clearwater
country: United States
facility: Gastro Florida
state: Florida
city: Clearwater
country: United States
facility: Innovative Research of West Florida, Inc.
state: Florida
city: Clearwater
country: United States
facility: Clinical Research of West Florida
state: Florida
city: Cooper City
country: United States
facility: ALL Medical Research LLC
state: Florida
city: Cutler Bay
country: United States
facility: American Research Institute, Inc
state: Florida
city: Cutler Bay
country: United States
facility: Top Medical Research
state: Florida
city: Hialeah
country: United States
facility: Palmetto Research, LLC
state: Florida
city: Homestead
country: United States
facility: Vida Clinical Trials
state: Florida
city: Inverness
country: United States
facility: Nature Coast Clinical Research
state: Florida
city: Jacksonville
country: United States
facility: University of Florida
state: Florida
city: Lakewood Ranch
country: United States
facility: Florida Research Institute
state: Florida
city: Maitland
country: United States
facility: Cfagi Llc
state: Florida
city: Miami Lakes
country: United States
facility: Panax Clinical Research
state: Florida
city: Miami Lakes
country: United States
facility: Savin Medical Group LLC
state: Florida
city: Miami
country: United States
facility: APF Research LLC
state: Florida
city: Miami
country: United States
facility: AMPM Research Clinic
state: Florida
city: Miami
country: United States
facility: Advanced Medical Research Institute
state: Florida
city: Miami
country: United States
facility: Florida Research Center, Inc.
state: Florida
city: Naples
country: United States
facility: Gastroenterology Group of Naples
state: Florida
city: Ocoee
country: United States
facility: Sensible Healthcare
state: Florida
city: Pensacola
country: United States
facility: Gulf Region Clinical Research Institute
state: Florida
city: Tampa
country: United States
facility: University of South Florida
state: Florida
city: Tampa
country: United States
facility: Gastro Florida
state: Florida
city: Weston
country: United States
facility: Cleveland Clinic Florida - Weston
state: Florida
city: Atlanta
country: United States
facility: Atlanta Diabetes Associates
state: Georgia
city: Atlanta
country: United States
facility: Emory University
state: Georgia
city: Blue Ridge
country: United States
facility: River Birch Research Alliance, LLC
state: Georgia
city: Buford
country: United States
facility: Gwinnett Research Institute
state: Georgia
city: Carnesville
country: United States
facility: Summit Clinical Research, LLC.
state: Georgia
city: Decatur
country: United States
facility: iResearch Atlanta LLC
state: Georgia
city: Riverdale
country: United States
facility: Infinite Clinical Trials
state: Georgia
city: Idaho Falls
country: United States
facility: Rocky Mountain Diabetes and Osteoporosis Center, PA
state: Idaho
city: Evanston
country: United States
facility: North Shore University Health System
state: Illinois
city: Oak Lawn
country: United States
facility: Southwest Gastroenterology
state: Illinois
city: Springfield
country: United States
facility: Southern Illinois University School of Medicine
state: Illinois
city: Evansville
country: United States
facility: MediSphere Medical Research Center, LLC
state: Indiana
city: Indianapolis
country: United States
facility: Indiana University Health University Hospital
state: Indiana
city: Jeffersonville
country: United States
facility: American Research, LLC
state: Indiana
city: Iowa City
country: United States
facility: University of Iowa Hospital and Clinics
state: Iowa
city: West Des Moines
country: United States
facility: Integrated Clinical Trial Services Inc
state: Iowa
city: Kansas City
country: United States
facility: University of Kansas Medical Center
state: Kansas
city: Pratt
country: United States
facility: Health Science Research Center
state: Kansas
city: Topeka
country: United States
facility: Cotton-O'Neil Clinical Research Center - Digestive Health
state: Kansas
city: Wichita
country: United States
facility: Professional Research Network of Kansas, LLC
state: Kansas
city: Wichita
country: United States
facility: Via Christi Clinic, PA
state: Kansas
city: Crestview Hills
country: United States
facility: Tri-State Gastroenterology
state: Kentucky
city: Louisville
country: United States
facility: University of Louisville
state: Kentucky
city: Bastrop
country: United States
facility: Delta Research Partners
state: Louisiana
city: Crowley
country: United States
facility: Avant Research Associates LLC
state: Louisiana
city: Houma
country: United States
facility: Cronola LLC
state: Louisiana
city: Lake Charles
country: United States
facility: Centex Studies, Inc. - Lake Charles- Clinical Trials of SWLA, LLC
state: Louisiana
city: Marrero
country: United States
facility: Tandem Clinical Research
state: Louisiana
city: Metairie
country: United States
facility: New Orleans Research Institute - Metropolitan Gastroenterology Associates
state: Louisiana
city: West Monroe
country: United States
facility: Clinical Trials of America, Inc.
state: Louisiana
city: Chevy Chase
country: United States
facility: Metropolitan Gastroenterology Group PC, Chevy Chase Clinical Research
state: Maryland
city: Columbia
country: United States
facility: Gastro Center of Maryland
state: Maryland
city: Glen Burnie
country: United States
facility: Woodholme Gastroenterology Associates, P.A.
state: Maryland
city: Brockton
country: United States
facility: Commonwealth Clinical Studies, PLLC.
state: Massachusetts
city: South Weymouth
country: United States
facility: Coastal Research Associates, Inc.
state: Massachusetts
city: West Roxbury
country: United States
facility: Boston VA Healthcare System
state: Massachusetts
city: Caro
country: United States
facility: Biocon Clinical Research, LLC
state: Michigan
city: Chesterfield
country: United States
facility: Clinical Research Institute of Michigan
state: Michigan
city: Flint
country: United States
facility: Aa Mrc, Llc
state: Michigan
city: Hamtramck
country: United States
facility: National Clinical, LLC
state: Michigan
city: Novi
country: United States
facility: Henry Ford Health System
state: Michigan
city: Troy
country: United States
facility: Troy Gastroenterology, PC dba Center for Digestive Health
state: Michigan
city: Wyoming
country: United States
facility: Gastroenterology Associates of Western Michigan
state: Michigan
city: Coon Rapids
country: United States
facility: MNGI Digestive Health
state: Minnesota
city: Saint Louis
country: United States
facility: Washington University in St. Louis
state: Missouri
city: Missoula
country: United States
facility: Montana Medical Research
state: Montana
city: Omaha
country: United States
facility: Heartland Clinical Research, Inc
state: Nebraska
city: Las Vegas
country: United States
facility: Clinical Research of South Nevada
state: Nevada
city: Las Vegas
country: United States
facility: Advanced Biomedical Research of America
state: Nevada
city: Las Vegas
country: United States
facility: Digestive Disease Specialists
state: Nevada
city: Las Vegas
country: United States
facility: Palm Research Center
state: Nevada
city: Brick
country: United States
facility: Test Center 3
state: New Jersey
city: Egg Harbor Township
country: United States
facility: AGA Clinical Research Associates, LLC
state: New Jersey
city: Albuquerque
country: United States
facility: Lovelace Scientific Resources, Inc.
state: New Mexico
city: Great Neck
country: United States
facility: Long Island Gastrointestinal Research Group LLP
state: New York
city: Jamaica
country: United States
facility: Queens Hospital Center
state: New York
city: Johnson City
country: United States
facility: United Health Services Hospitals, Inc.
state: New York
city: Mineola
country: United States
facility: NYU Winthrop Hospital, Clinical Trials Center
state: New York
city: New York
country: United States
facility: Weill Cornell Medical College
state: New York
city: Asheville
country: United States
facility: Asheville Gastroenterology Associates
state: North Carolina
city: Chapel Hill
country: United States
facility: University of North Carolina at Chapel Hill
state: North Carolina
city: Charlotte
country: United States
facility: Test Center 2
state: North Carolina
city: Concord
country: United States
facility: PMG Research of Charlotte, LLC
state: North Carolina
city: Davidson
country: United States
facility: Carolina Digestive Health Associates, PA
state: North Carolina
city: Fayetteville
country: United States
facility: Cumberland Research Associates, LLC
state: North Carolina
city: Greensboro
country: United States
facility: Triad Clinical Trials
state: North Carolina
city: Kinston
country: United States
facility: Vidant Multispeciality Clinic - Kinston
state: North Carolina
city: Morehead City
country: United States
facility: Diabetes and Endocrinology Consultants, PC
state: North Carolina
city: Salisbury
country: United States
facility: PMG Research Salisbury
state: North Carolina
city: Wilmington
country: United States
facility: PMG Research of Wilmington, LLC
state: North Carolina
city: Winston-Salem
country: United States
facility: PMG Research of Winston-Salem, LLC
state: North Carolina
city: Winston-Salem
country: United States
facility: The Center for Clinical Research
state: North Carolina
city: Winston-Salem
country: United States
facility: Wake Forest Baptist Health
state: North Carolina
city: Beavercreek
country: United States
facility: Dayton Gastroenterology,Inc.
state: Ohio
city: Cleveland
country: United States
facility: The MetroHealth System MHS
state: Ohio
city: Cleveland
country: United States
facility: Digestive Disease & Surgery Institute
state: Ohio
city: Columbus
country: United States
facility: Endocrinology Research Associates, Inc.
state: Ohio
city: Columbus
country: United States
facility: The Ohio State University, Wexner Medical Center
state: Ohio
city: Columbus
country: United States
facility: Aventiv Research, Inc.
state: Ohio
city: Columbus
country: United States
facility: Hometown Urgent Care and Research
state: Ohio
city: Dayton
country: United States
facility: Clinical Inquest Center Ltd.
state: Ohio
city: Wadsworth
country: United States
facility: Family Practice Center of Wadsworth, Inc. DBA New Venture Medical Research
state: Ohio
city: Oklahoma City
country: United States
facility: Digestive Disease Specialists Inc
state: Oklahoma
city: Oklahoma City
country: United States
facility: Memorial Clinical Research
state: Oklahoma
city: Tulsa
country: United States
facility: Options Health Research, LLC
state: Oklahoma
city: Levittown
country: United States
facility: Family Medical Associates, Research Department
state: Pennsylvania
city: Philadelphia
country: United States
facility: University of Pennsylvania
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Allegheny Endocrinology Associates
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Preferred Primary Care Physicians, Inc.
state: Pennsylvania
city: Sayre
country: United States
facility: Guthrie Clinical Research
state: Pennsylvania
city: Scottdale
country: United States
facility: Frontier Clinical Research, LLC
state: Pennsylvania
city: Smithfield
country: United States
facility: Montgomery Medical, Inc.
state: Pennsylvania
city: Uniontown
country: United States
facility: Preferred Primary Care Physicians, Jacob Murphy
state: Pennsylvania
city: Cumberland
country: United States
facility: Partners in Clinical Research, LLC
state: Rhode Island
city: Charleston
country: United States
facility: Clinical Trials of South Carolina
state: South Carolina
city: Greenville
country: United States
facility: Gastroenterology Associates, PA
state: South Carolina
city: Rapid City
country: United States
facility: Health Concepts
state: South Dakota
city: Chattanooga
country: United States
facility: Clinsearch
state: Tennessee
city: Germantown
country: United States
facility: Gastro One
state: Tennessee
city: Nashville
country: United States
facility: Quality Medical Research
state: Tennessee
city: Arlington
country: United States
facility: Texas Clinical Research Institute, LLC
state: Texas
city: Austin
country: United States
facility: Avant Research Associates,LLC
state: Texas
city: Beaumont
country: United States
facility: DiscoveResearch, Inc.
state: Texas
city: Carrollton
country: United States
facility: ClinRx Research, LLC
state: Texas
city: El Paso
country: United States
facility: Texas Tech University Health Sciences, Center Division of Gastroenterology
state: Texas
city: Garland
country: United States
facility: DHAT Research Institute
state: Texas
city: Houston
country: United States
facility: Baylor College of Medicine Medical Center
state: Texas
city: Houston
country: United States
facility: Biopharma Informatic Inc., Research Center
state: Texas
city: Houston
country: United States
facility: Rodriguez Clinical Trials
state: Texas
city: Houston
country: United States
facility: Amir Ali Hassan, MD, PA
state: Texas
city: San Antonio
country: United States
facility: Digestive Center of South Texas
state: Texas
city: San Antonio
country: United States
facility: Clinical Trials of Texas, Inc.
state: Texas
city: San Antonio
country: United States
facility: SAGACT PLLC., San Antonio Gastroenterology Associates, PA
state: Texas
city: Southlake
country: United States
facility: Texas Digestive Disease Consultants
state: Texas
city: Ogden
country: United States
facility: Advanced Research Institute, Inc.
state: Utah
city: Salt Lake City
country: United States
facility: Test Center
state: Utah
city: West Jordan
country: United States
facility: Advanced Clinical Research
state: Utah
city: Fairfax
country: United States
facility: Verity Research Inc.
state: Virginia
city: Lynchburg
country: United States
facility: Blue Ridge Medical Research
state: Virginia
city: Manassas
country: United States
facility: Manassas Clinical Research Centre
state: Virginia
city: Richmond
country: United States
facility: VA Medical Center McGuire VAMC
state: Virginia
city: Roanoke
country: United States
facility: Test Center 4
state: Virginia
city: Woodbridge
country: United States
facility: Cardinal Internal Medicine
state: Virginia
city: Tacoma
country: United States
facility: Washington Gastroenterology PLLC
state: Washington
city: Morgantown
country: United States
facility: West Virginia University
state: West Virginia
city: C.a.b.a.
country: Argentina
facility: Maffei Centro Medico-Investigacion Clinica Aplicada
state: Buenos Aires Province
city: Caba
country: Argentina
facility: Hospital Sirio Libanes
state: Buenos Aires Province
city: Ciudad Autonoma de Buenos Aires
country: Argentina
facility: CIPREC
state: Buenos Aires Province
city: Rosario
country: Argentina
facility: Instituto de Investigaciones Clínicas de Rosario
state: Santa Fe
city: Rosario
country: Argentina
facility: Instituto de hematología y medicina clínica "Dr. Rubén Dávoli"
state: Santa Fe
city: Corrientes
country: Argentina
facility: Centro Universitario de Investigacion en Farmacologia Clinic
city: Kingswood
country: Australia
facility: Nepean Hospital
state: New South Wales
city: Woolloongabba
country: Australia
facility: Princess Alexandra Hospital
state: Queensland
city: Adelaide
country: Australia
facility: Royal Adelaide Hospital - Central Adelaide Local Health Network Incorporated
state: South Australia
city: Melbourne
country: Australia
facility: The Alfred Hospital
state: Victoria
city: Parkville
country: Australia
facility: Royal Melbourne Hospital
state: Victoria
city: Saint Stefan
country: Austria
facility: Ordination
state: Steiermark
city: Innsbruck
country: Austria
facility: Medizinische Universitaet Innsbruck
state: Tirol
city: Feldkirch
country: Austria
facility: VIVIT Institute, am LKH Feldkirch
state: Vorarlberg
city: Klagenfurt
country: Austria
facility: Klinikum Klagenfurt am Wörthersee
city: Salzburg
country: Austria
facility: Privatklinik Wehrle-Diakonissen
city: Steyr
country: Austria
facility: Oö. Gesundheits- und Spitals-AG/LKH Steyr
city: Vienna
country: Austria
facility: Krankenanstalt Rudolfstiftung Wien
city: Vienna
country: Austria
facility: KH Hietzing
city: Brugge
country: Belgium
facility: AZ Sint Lucas Brugge
state: Antwerpen
city: Edegem
country: Belgium
facility: Universitair Ziekenhuis Antwerpen, Gastro-Enterologie,
state: Antwerpen
city: Brussels
country: Belgium
facility: Hôpitaux Iris Sud - Joseph Bracops
city: Jette
country: Belgium
facility: UZ Brussel
city: Liège
country: Belgium
facility: CHC - Clinique Saint-Joseph
city: Fortaleza
country: Brazil
facility: Hospital Universitário Walter Cantídio
state: Ceara
city: Brasilia
country: Brazil
facility: Centro de Pesquisa Clinica do Brasil
state: Distrito Federal
city: Curitiba
country: Brazil
facility: Quanta Diagnóstico e Terapia
state: Parana
city: Belém
country: Brazil
facility: Hospital Universitário João de Barros Barreto - UFPA
state: Para
city: Passo Fundo- RS
country: Brazil
facility: Hospital Sao Vicente de Paulo
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Hospital de Clinicas de Porto Alegre
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Hospital São Lucas da PUC-RS
state: Rio Grande Do Sul
city: Joinville
country: Brazil
facility: Instituto Catarinense de Endocrinologia e Diabetes (ICED)
state: Santa Catarina
city: Campinas
country: Brazil
facility: Scentryphar Pesquisa Clínica Ltda
state: Sao Paulo
city: Campinas
country: Brazil
facility: Instituto de Pesquisa Clínica em Campinas
state: Sao Paulo
city: Cerqueira Cesar - Sao Paulo
country: Brazil
facility: Universidade de Sao Paulo (USP) - Hospital das Clinicas da F
state: Sao Paulo
city: São Paulo
country: Brazil
facility: IPEC-Instituto de Pesquisa Clinica
state: Sao Paulo
city: São Paulo
country: Brazil
facility: CPQuali Pesquisa Clínica Ltda
state: Sao Paulo
city: Fortaleza
country: Brazil
facility: Instituto de Estudos e Pesquisas Clínicas do Ceará - IEP/CE - Oncology
city: Byala
country: Bulgaria
facility: MHAT Yuliya Vrevska Byala
city: Dobrich
country: Bulgaria
facility: MHAT Dobrich AD
city: Gabrovo
country: Bulgaria
facility: MHAT Dr. Tota Venkova AD
city: Plovdiv
country: Bulgaria
facility: UMHAT - Kaspela- EOOD
city: Sofia
country: Bulgaria
facility: Medical Center Asklepion - Humane Medicine Research EOOD
city: Sofia
country: Bulgaria
facility: Alexandrovska University Hospital
city: Calgary
country: Canada
facility: University of Calgary
state: Alberta
city: Edmonton
country: Canada
facility: Alberta Diabetes Institute
state: Alberta
city: Vancouver
country: Canada
facility: Vancouver General Hospital
state: British Columbia
city: St. John's
country: Canada
facility: Eastern Health
state: Newfoundland and Labrador
city: Bridgewater
country: Canada
facility: South Shore Medical Arts
state: Nova Scotia
city: Etobicoke
country: Canada
facility: Dr. Anil K. Gupta Medicine Professional Corporation
state: Ontario
city: Ottawa
country: Canada
facility: The Ottawa Hospital
state: Ontario
city: Toronto
country: Canada
facility: Sunnybrook Health Science Centre
state: Ontario
city: Toronto
country: Canada
facility: Toronto Western Hospital, University Health Network
state: Ontario
city: Toronto
country: Canada
facility: Toronto Liver Centre
state: Ontario
city: Greenfield Park
country: Canada
facility: CISSS de la Monteregie-Centre
state: Quebec
city: Montreal
country: Canada
facility: Recherche GCP Research
state: Quebec
city: Montreal
country: Canada
facility: Centre Hospitalier de l'Universite de Montreal - CHUM
state: Quebec
city: Red Deer
country: Canada
facility: Central Alberta Research Centre
city: Vaughan
country: Canada
facility: Toronto Digestive Disease Associates
city: Medellin
country: Colombia
facility: Rodrigo Botero S.A.S.
state: Antioquia
city: Barranquilla
country: Colombia
facility: Centro Cardiovascular y de Diabetes
state: Atlántico
city: Barranquilla
country: Colombia
facility: Fundación BIOS
state: Atlántico
city: Bogota
country: Colombia
facility: Endocare Ltda.
state: Cundinamarca
city: Zipaquirá
country: Colombia
facility: Healthy Medical Center
state: Cundinamarca
city: Bogotá
country: Colombia
facility: Medplus Medicina Prepagada
state: Distrito Capltal
city: Cali
country: Colombia
facility: Centro Medico Imbanaco de Cali S.A.
state: Distrito Capltal
city: Cali
country: Colombia
facility: IPS Centro Medico Julian Coronel S.A
state: Valle Del Cauca
city: Hvidovre
country: Denmark
facility: Gastroenheden, Hvidovre hospital
state: Kobenhavn
city: Aalborg
country: Denmark
facility: Aalborg University Hospital
city: Hellerup
country: Denmark
facility: Steno Diabetes Center Copenhagen
city: Hilleroed
country: Denmark
facility: Nordsjaellands Hospital
city: Aarhus
country: Denmark
facility: MEA KFA
state: Århus
city: Pessac
country: France
facility: CHU de Bordeaux - Hôpital Haut-Lévêque
state: Gironde
city: Colombes
country: France
facility: Hôpital Louis-Mourier
city: Corbeil Essonnes
country: France
facility: Corbeil Essonnes
city: Grenoble
country: France
facility: Service d'hépato-gastroentérologie - 7°D
city: LYON Cedex 03
country: France
facility: Hospices Civils de Lyon - Hôpital Edouard Herrriot
city: Nantes
country: France
facility: CHU Nantes
city: Poitiers
country: France
facility: CHU de Poitiers
city: Rouen Cedex
country: France
facility: Hopital Charles Nicolle
city: Vandoeuvre-lès-Nancy
country: France
facility: CHRU Nancy
city: Venissieux
country: France
facility: Centre de Recherche Clinique
city: Karlsruhe
country: Germany
facility: Klinische Forschung Karlsruhe GmbH
state: Baden-Württemberg
city: Ulm
country: Germany
facility: Praxis Dr. Etzrodt-Walter und Kollegen
state: Baden-Württemberg
city: Schwerin
country: Germany
facility: Klinische Forschung Schwerin GmbH
state: Mecklenburg-Western Pomerania
city: Bad Berleburg
country: Germany
facility: Diabetologische Schwerpunktpraxis
state: North Rhine-Westphalia
city: Dresden
country: Germany
facility: Klinische Forschung Dresden GmbH
state: Saxony
city: Böhlen
country: Germany
facility: Studienzentrum Schwittay
city: Giessen
country: Germany
facility: Universitätsklinikum Giessen und Marburg GmbH
city: Hamburg
country: Germany
facility: Klinische Forschung Hamburg GmbH
city: Hamburg
country: Germany
facility: Clinical Research Hamburg GmbH
city: Hamburg
country: Germany
facility: Israelitisches Krankenhaus
city: Hannover
country: Germany
facility: Klinische Forschung Hannover-Mitte GmbH
city: Hannover
country: Germany
facility: KRH Klinikum Siloah
city: Eger
country: Hungary
facility: Markhot Ferenc Oktatokorhaz es Rendelointezet
state: Heves
city: Pecs
country: Hungary
facility: Coromed SMO
state: Pécs
city: Szeged
country: Hungary
facility: First Department of Medicine, University of Szeged
state: Szaged
city: Zalaegerszeg
country: Hungary
facility: Zala Megyei Szent Rafael Korhaz
state: Zala
city: Budapest
country: Hungary
facility: Semmelweis University
city: Budapest
country: Hungary
facility: Stra¡zshegy Medicina
city: Szolnok
country: Hungary
facility: Hetenyi Geza Hospital
city: Visakhapatnam
country: India
facility: King George Hospital
state: Andhra Pradesh
city: Ahmedabad
country: India
facility: Dr. Jivraj Mehta Smarak Health Foundation Bakeri Medical Res
state: Gujarat
city: Ahmedabad
country: India
facility: Zydus Hospital
state: Gujarat
city: Surat
country: India
facility: Surat Institute of Digestive Sciences Hospitals
state: Gujarat
city: Bangalore
country: India
facility: Lifecare Clinic and Research Centre - Internal Med/Diabetolo
state: Karnataka
city: Bengaluru
country: India
facility: Diacon Hospital and research Center
state: Karnataka
city: Bengaluru
country: India
facility: Victoria Hospital Bangalore Medical College and Research Ins
state: Karnataka
city: Bengaluru
country: India
facility: Rajalakshmi Hospital
state: Karnataka
city: Mangalore
country: India
facility: Vinaya Hospital & Research Centre
state: Karnataka
city: Nashik
country: India
facility: Chopda Medicare & Research Centre Pvt.Ltd, Magnum Heart Institute
state: Maharashtra
city: Pune
country: India
facility: B. J. Government Medical College and Sassoon General Hospitals
state: Maharashtra
city: Pune
country: India
facility: Grant Medical Foundation Ruby Hall Clinic
state: Maharashtra
city: Pune
country: India
facility: University Hospital
state: Maharashtra
city: Pune
country: India
facility: Noble Hospital
state: Maharashtra
city: Bikaner
country: India
facility: S.P.Medical College & Group of Hospitals Bikaner
state: Rajasthan
city: Jaipur
country: India
facility: S.R. Kalla Memorial Gastro and General Hospital
state: Rajasthan
city: Jaipur
country: India
facility: Sawai Man Singh Hospital
state: Rajasthan
city: Jaipur
country: India
facility: Sir Ganga Ram Hospital (SGRH)
state: Rajasthan
city: Jaipur
country: India
facility: Marudhar Hospital
state: Rajasthan
city: Jaipur
country: India
facility: Eternal Hospital, Unit of Eternal Heart Care Centre and Research Institute Pvt. Ltd.
state: Rajasthan
city: Chennai
country: India
facility: Madras Medical College & Rajiv Gandhi Govt. General Hospital
state: Tamil Nadu
city: Chennai
country: India
facility: M.V. Hospital for Diabetes & Diabetes Research Centre
state: Tamil Nadu
city: Coimbatore
country: India
facility: Kovai Diabetes Speciality Centre
state: Tamil Nadu
city: Madurai
country: India
facility: Arthur Asirvatham Hospital
state: Tamil Nadu
city: Lucknow
country: India
facility: M V Hospital & Research Centre
state: Uttar Pradesh
city: Kolkata
country: India
facility: IPGME&R and SSKM Hospital
state: West Bengal
city: Bangalore
country: India
facility: M. S. Ramaiah medical College and Hospitals - Gastroenterolo
city: Hyderabad
country: India
facility: Gleneagles Global Hospital
city: Hyderabad
country: India
facility: Kumudini Devi Diabetes Research Center
city: Mumbai
country: India
facility: Bhatia Hospital
city: Beer Sheva
country: Israel
facility: Soroka University Medical Center
city: Haifa
country: Israel
facility: Bnai Zion M.C.
city: Holon
country: Israel
facility: E. Wolfson Medical Center
city: Jerusalem
country: Israel
facility: Digestive Diseases Institute
city: Petach Tikva
country: Israel
facility: Gastroenterology Institute
city: Safed
country: Israel
facility: Endocrinology & Diabetes Center
city: Tel Aviv
country: Israel
facility: Gastroenterology Institute
city: San Donato Milanese
country: Italy
facility: IRCCS Policlinico San Donato
state: Milan
city: Vigevano
country: Italy
facility: Clinical Institute Beato Matteo
state: Pavia
city: Rome
country: Italy
facility: Policlinico Gemelli, Divisione di Endocrinologia e Malattie del Metabolismo
state: Rome Roma
city: Asti
country: Italy
facility: Ospedale Cardinal Massaia
city: Bari
country: Italy
facility: University of Bari
city: Catania
country: Italy
facility: Azienda Ospedaliera Rilievo Nazionale Alta Specialita (ARNAS) Garibaldi
city: Catanzaro
country: Italy
facility: Universita Magna Graecia di Catanzaro
city: Genova
country: Italy
facility: IRCCS Azienda Ospedaliera Universitaria San Martino
city: Napoli
country: Italy
facility: Universita degli Studi di Napoli Federico II
city: Padova
country: Italy
facility: Azienda Opsedaliera di Padova
city: Pavia
country: Italy
facility: IRCCS S.Matteo Hospital Foundation, University of Pavia
city: Pisa
country: Italy
facility: University of Pisa - Cisanello Hospital
city: Rozzano
country: Italy
facility: Gruppo Humanitas - Humanitas Research Hospital
city: Salerno
country: Italy
facility: Universita' Di Salerno- Aou Ruggi D'aragona
city: San Giovanni Rotondo
country: Italy
facility: IRCCS Ospedale Casa Sollievo della Sofferenza
city: Jeonju
country: Korea, Republic of
facility: Chonbuk National University Hospital
state: Jeollabuk-do
city: Seoul
country: Korea, Republic of
facility: Sanggye Paik Hospital, Inje University College of Medicine
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center
city: Daugavpils
country: Latvia
facility: Polana-D
city: Kraslava
country: Latvia
facility: Ogorelova Jelena GP
city: Riga
country: Latvia
facility: Pauls Stradins Clinical University Hospital, Endokrinologijas nodala
city: Riga
country: Latvia
facility: Digestive Diseases Centre GASTRO
city: Alor Setar
country: Malaysia
facility: Hospital Sultanah Bahiyah
state: Kedah
city: Kuala Lumpur
country: Malaysia
facility: University Malaya Medical Centre
city: Kubang Kerian
country: Malaysia
facility: Universiti Sains Malaysia
city: Taiping
country: Malaysia
facility: Hospital Taiping
city: Mexico
country: Mexico
facility: Clinicos Asociados BOCM SC
state: Distrito Federal
city: Mexico
country: Mexico
facility: Clinica OMEGA
state: Distrito Federal
city: Mexico
country: Mexico
facility: Instituto Nacional de Ciencias Medicas y Nutricion
state: Distrito Federal
city: México DF
country: Mexico
facility: Medical and Nutritional Trials
state: Distrito Federal
city: León
country: Mexico
facility: Centro de Investigacion Morales Vargas - CIMOVA
state: Guanajuato
city: Pachuca
country: Mexico
facility: Centro de Diabetes de Pachuca
state: Hidalgo
city: Guadalajara
country: Mexico
facility: Unidad de Investigación Clínica Cardiometabolica de Occidente
state: Jalisco
city: Guadalajara
country: Mexico
facility: Consultorio Medico
state: Jalisco
city: Guadalajara
country: Mexico
facility: Unidad de Investigación clínica y atención Médica HEPA S.C.
state: Jalisco
city: Cuautla
country: Mexico
facility: Instituto de Diabetes Obesidad y Nutrición SC
state: Morelos
city: Monterrey
country: Mexico
facility: Accelerium Clinical Research
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Centro Medico Christus Muguerza Sur
state: Nuevo Leon
city: Hermosillo
country: Mexico
facility: Investigación Médica Sonora, S.C.
state: Sonora
city: Boca del Rio
country: Mexico
facility: Centro Especializado en Investigación Clínica S.C.
state: Veracruz
city: Mérida
country: Mexico
facility: Centro de Desarrollo Biomédico
state: Yucatan
city: Acapulco
country: Mexico
facility: Practice Dr Gerardo Gonzalez
city: Aguascalientes
country: Mexico
facility: Hospital Cardiológica Aguascalientes
city: Durango
country: Mexico
facility: Dioderm Instituto de Investigación
city: Durango
country: Mexico
facility: CIADEN (Centro de Investigación y Atención de Diabetes, Endocrinología y Nutrición)
city: Veracruz
country: Mexico
facility: Sociedad de Metabolismo y Corazón, S.C.
city: Cebu City
country: Philippines
facility: Perpetual Succor Hospital
city: IloIlo City
country: Philippines
facility: West Visayas State University Medical Center
city: Makati City
country: Philippines
facility: Ospital ng Makati
city: Manila
country: Philippines
facility: Manila Doctors Hospital
city: Pasay
country: Philippines
facility: San Juan De Dios Educational Foundation, Inc.
city: Quezon City
country: Philippines
facility: St. Luke's Medical Center
city: San Juan
country: Philippines
facility: Cardinal Santos Medical Center
city: Ystok
country: Poland
facility: NZOZ Vita - Diabetica Malgorzata Buraczyk, Diabetes Clinic,
state: Bia
city: Warszawa
country: Poland
facility: Centrum Medyczne Pratia Warszawa
state: Warazawa
city: Bialystok
country: Poland
facility: Szpital Uniwestytetu Medycznego w Bialymstoku
city: Bydgoszcz
country: Poland
facility: Nasz Lekarz Osrodek Badan Klinicznych
city: Bydgoszcz
country: Poland
facility: Vitamed
city: Chojnice
country: Poland
facility: Centrum Medyczne Lukamed
city: Katowice
country: Poland
facility: Silmedic Sp z o o
city: Krakow
country: Poland
facility: CenterMed Krakow Ltd
city: Kraków
country: Poland
facility: Specjalistyczny Gabinet Neurologiczny Marta Banach
city: Lublin
country: Poland
facility: Centrum Medyczne Medyk
city: Olsztyn
country: Poland
facility: Wojewodzki Szpital Specjalistyczny w Olsztynie
city: Pruszków
country: Poland
facility: Oddzial Gastroenterologii Mazowieckie Centrum Rehabilitacji Stocer sp. Z o.o.
city: Sopot
country: Poland
facility: Endoskopia SP. Z O.O.
city: Wołów
country: Poland
facility: Powiatowe Centrum Medyczne w Wołowie
city: Wrocław
country: Poland
facility: Centrum Badan Klinicznych Piotr Napora Lekarze Spolka Partnerska
city: Zamość
country: Poland
facility: Zamość
city: Bucharest
country: Romania
facility: Sana Medical Center
city: Bucharest
country: Romania
facility: National Institute of Endocrinology
city: Calarasi
country: Romania
facility: AMES Research Center SRL
city: Dobrosloveni Resca, Olt County
country: Romania
facility: ClinTrial Medical Center, Pulmonology Department
city: Sibiu
country: Romania
facility: Polisano-Clinic
city: Novosibirsk
country: Russian Federation
facility: Scientific Institute of Clinical and Experimental Lymphology
state: Novosibirskaya Oblast
city: Saint-Petersburg
country: Russian Federation
facility: North-Western State Medical University named after I. I. Mechnikov
state: Sankt-Peterburg
city: Saint-Petersburg
country: Russian Federation
facility: Millitary-medical Academy, department of hospital therapy
state: Sankt-Peterburg
city: Kazan
country: Russian Federation
facility: Kazan State Medical University
city: Leningrad Region
country: Russian Federation
facility: Saint-Petersburg City Pokrovskaya Hospital
city: Moscow
country: Russian Federation
facility: FSBI National medical endocrinology research centre
city: Moscow
country: Russian Federation
facility: Moscow Regional Research Clinical Institute named by MF Vladimirski
city: Nizhny
country: Russian Federation
facility: Nizhegorodsky Regional Clinical Hospital named after N. A. Semashko
city: Rostov on Don
country: Russian Federation
facility: Rostov on Don
city: Rostov-on-Don
country: Russian Federation
facility: Rostov State Medical University
city: Saratov
country: Russian Federation
facility: MUZ City Clinical Hospital 9
city: Saratov
country: Russian Federation
facility: Saratov City Clinical Hospital 12
city: Singapore
country: Singapore
facility: National University Hospital
city: Singapore
country: Singapore
facility: Singapore General Hospital
city: Singapore
country: Singapore
facility: Changi General Hospital
city: Bloemfontein
country: South Africa
facility: FARMOVS
state: Free State
city: Johannesburg
country: South Africa
facility: Soweto CTC
state: Gauteng
city: Johannesburg
country: South Africa
facility: Wits Clinical Research
state: Gauteng
city: Pretoria
country: South Africa
facility: Synexus Stanza Clincal Reaserch Centre
state: Gauteng
city: Paarl
country: South Africa
facility: Endocare Research
state: Western Cape
city: Brandfort
country: South Africa
facility: Moriana Clinical Research
city: Cape Town
country: South Africa
facility: Synexus Helderberg Clinical Research Centre
city: Cape Town
country: South Africa
facility: TREAD Research
city: Val De Grace
country: South Africa
facility: Syenxus Watermeyer Dedicated Research
city: Madrid
country: Spain
facility: Hospital Universitario 12 de Octubre
city: Madrid
country: Spain
facility: Hospital Clinico Universitario San Carlos
city: Madrid
country: Spain
facility: Hospital Universitario La Paz
city: Madrid
country: Spain
facility: Hospital Universitario Principe de Asturias
city: Salamanca
country: Spain
facility: Hospital Clinico Universitario de Salamanca
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen del Rocío
city: Zaragoza
country: Spain
facility: Hospital Universitario Miguel Servet
city: Bangkok
country: Thailand
facility: Phramongkutklao Hospital
city: Bangkok
country: Thailand
facility: Faculty of Medicine, Siriraj Hospital, Mahidol University
city: Chiang Mai
country: Thailand
facility: Maharaj Nakorn Chiang Mai Hospital
city: Dnipropetrovsk Region
country: Ukraine
facility: "Kryvyi Rih City Hospital #3" of Dnipropetrovsk Regional Council
state: Dnipropetrovs'ka Oblast
city: Dnipro
country: Ukraine
facility: State Institution Ukrainian State Research Institute
state: Dnipropetrovs'ka Oblast
city: Ivano-Frankivsk
country: Ukraine
facility: Ivano-Frankivsk National Medical University
state: Ivano-Frankivs'ka Oblast'
city: Kyiv
country: Ukraine
facility: Kyiv city clinical endocrinology center, department of general endocrine pathology and metabolism, c. Kyiv
state: Kyïv
city: Vinnytsya
country: Ukraine
facility: DRRI-Vinnytsia National Pirogov Memorial Medical University
state: Vinnyts'ka Oblast'
city: Lutsk
country: Ukraine
facility: Municipal Institution Lutsk City Clinical Hospital
state: Volyos'ka Oblast'
city: Chernihiv
country: Ukraine
facility: Municipal nonprofit entity "Chernigiv city hospital #2" of Chernigiv municipal council, therapeutic department
city: Chernivtsi
country: Ukraine
facility: Regional municipal institution "Chernivtsi's regional clinical hospital", gastroenterological department, Higher state educational establishment of Ukraine "Bukovinian state medical university", department of internal medicine and infectious diseases, c.C
city: Chernivtsi
country: Ukraine
facility: Regional Public Organization Chernivtsi Regional Endocrinology Center
city: Dnipro
country: Ukraine
facility: SU Clinic of medical academy of SI Dnepropetrovsk medical cacadamy of MoH of Ukraine
city: Ivano-Frankivsk
country: Ukraine
facility: Ivano-Frankivsk Central City Clinical Hospital
city: Kharkiv
country: Ukraine
facility: Municipal nonprofit entity "City clinical hospital #2 n.a. Prof.O.O.Shalimov" of Kharkiv municipal council, department of endocrinology
city: Kharkiv
country: Ukraine
facility: "State Institution "National Institute of Therapy named after. L.T. Maloi NAMNU" / Government Institution "L.T.Malaya Therapy National Institute of the National Academy of Medical Sciences of Ukraine", Department of the study of diseases of the digestive
city: Kharkiv
country: Ukraine
facility: Clinical Endocrinology of SI V.Danilevsky Institute for endocrine pathology problems National Academy of Medical sciences of Ukraine
city: Kherson
country: Ukraine
facility: Communal Institution Kherson City Clinical Hospital
city: Kyiv
country: Ukraine
facility: Limited Liability Company "Medical and Diagnostic Center "ADONIS Plus", outpatient department, c. Kyiv
city: Kyiv
country: Ukraine
facility: Kyiv Railway Clinical Hospital #2 of Branch Healthcare Center of the PJSC Ukranian Railway, Endocrynology Department
city: Kyiv
country: Ukraine
facility: Medical Center Universal Clinic OberigMedical Center Universal Clinic Oberig / Medical Center "Universal Clininc "Oberig" of LLC "Capital", Gastroenterological Center, c. Kyiv
city: Kyiv
country: Ukraine
facility: Polyclinic of medical services and rehabilitation department of State Joint-Stock Holding Company Artem, day-patient unit
city: Kyiv
country: Ukraine
facility: Institute of Endocrinology and Metabolism im. V. P. Komisarenka NAMS Ukraine
city: Mykolaiv
country: Ukraine
facility: City Hospital #1, department of endocrinology, c. Mykolayiv
city: Odesa
country: Ukraine
facility: Odessa Railway Clinical Hospital of Branch of HC JSC Ukrzaliznytsia, Odessa National Medical University
city: Odesa
country: Ukraine
facility: Communal Institution "Odesa Regional Clinical Hospital", Out-patient department
city: Poltava
country: Ukraine
facility: Poltava Regional Clinical Hospital
city: Sumy
country: Ukraine
facility: Municipal Institution of Sumy Regional Council Sumy Regional Clinical Hospital
city: Ternopil
country: Ukraine
facility: Ternopil University Hospital, Regional Center for Gastroenterology with Hepatology, Department of Gastroenterology
city: Vinnytsia
country: Ukraine
facility: Private Small-Scale Enterprise Medical Center Pulse
city: Vinnytsia
country: Ukraine
facility: Medical Center of the Limited Liability Company "Health Clinic", Medical Clinical Research Center, Department of Gastroenterology, Hepatology and Endocrinology
city: Vinnytsia
country: Ukraine
facility: Vinnytsia Regional Clinical highly specialized Endocrinology Centre
city: Vinnytsia
country: Ukraine
facility: Municipal nonprofit entity "Vinnytsia's city clinical hospital #1", gastroenterological department, Vinnytsia National Pirogov Memorial Medical University, department of propedeutics of internal medicine, c. Vinnytsia
city: Zaporizhzhia
country: Ukraine
facility: 6th City Clinical Hospital, c. Zaporizhzhia
city: Zaporizhzhia
country: Ukraine
facility: Municipal Institution "City Hospital #7", polyclinic department, c. Zaporizhzhia
city: Zaporizhzhia
country: Ukraine
facility: Municipal Institution-Zaporizhzhia Regional Clinical Hospital
city: Oldham
country: United Kingdom
facility: Royal Oldham Hospital
state: Lancashire
city: Cannock
country: United Kingdom
facility: MAC Research, Exchange House
state: Staffordshire
city: Stoke on Trent
country: United Kingdom
facility: University Hospitals of North Midlands
state: Staffordshire
city: Barnsley
country: United Kingdom
facility: MAC Research
city: Blackpool
country: United Kingdom
facility: MAC Clinical Research, Kaman Court
city: Chelmsford
country: United Kingdom
facility: Mid Essex Hospital Services NHS Trust Broomfield Hospital
city: Edinburgh
country: United Kingdom
facility: Western General Hospital Edinburgh
city: Leeds
country: United Kingdom
facility: MAC Clinical Research, Monarch House
city: Liverpool
country: United Kingdom
facility: MAC Clinical Research
city: London
country: United Kingdom
facility: Wingate Institute
city: London
country: United Kingdom
facility: University College London Hospita
city: Manchester
country: United Kingdom
facility: MAC Clinical Research Manchester
city: Manchester
country: United Kingdom
facility: University Hospital of South Manchester
city: Newcastle upon Tyne
country: United Kingdom
facility: The Newcastle upon Tyne Hospitals NHS Foundation Trust
city: Nottingham
country: United Kingdom
facility: Biomedical Research Centre
city: Stockton-on-Tees
country: United Kingdom
facility: MAC Clinical Research, GAC House
city: Tooting
country: United Kingdom
facility: St George's Hospital
city: Wolverhampton
country: United Kingdom
facility: Royal Wolverhampton NHS Trust
Study officials:
affiliation: Allergan
name: Harvy Schneier
role: STUDY_DIRECTOR
References: