Clinical trial NCT04352426: Symptom-limited Stair Climbing Test in Heart Failure
Official title: Effectiveness of Symptom-limited Stair-climbing Test in the Determination of the Exercise Capacity of Patients With Chronic Heart Failure
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Chronic Heart Failure
Keywords: chronic heart failure
exercise capacity
symptom-limited stair-climbing test
Lead sponsor: KTO Karatay University
Sponsor class: OTHER
First posted: 2020-04-20
Enrollment: 31
Sex: ALL
Minimum age (years): 50
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Thirty-one patients age 65.52±7.57 years with stage II-III according to the NYHA classification, diagnosed with CHF, with a LVEF of 45% or less admitted to study.

Brief summary: Aims: To assess the efficacy of symptom-limited stair-climbing test (SLSCT), in determining the exercise capacities of patients with chronic heart failure (CHF) in comparison with cardiopulmonary exercise test (CPET) and 6-minute walk test(6MWT) and to interpret the results according to the clinical status of the patients.

Methods: Thirty-one patients, aged 50-75 years, with stage II-III CHF according to the New York Heart Association Classification and left ventricular ejection fraction (LVEF) of ≤45% were included. The demographic and clinical characteristics of the patients were recorded. Exercise capacity was assessed by SLSCT, 6MWT, and CPET. The duration of patients' performance in the test, reasons for ending the test and predicted maximal oxygen consumption (VO2max) were recorded. Heart rate (HR), blood pressure (BP), dyspnoea severity \[Modified Borg Scale (MBS)\] and peripheral oxygen saturation were recorded. Pulmonary functions were assessed by spirometry.


Eligibility criteria: Inclusion Criteria:

* 50-75 years of age
* NYHA stage II-III
* LVEF of 45% or less
* Independently walking and climbing stairs
* Volunteer to participate in research

Exclusion Criteria:

* Any acute or chronic condition that would limit exercise capacity other than CHF
* Insufficient mental status to perform tests and surveys
* Orthopaedic problem limiting exercise test in lower extremity
* Severe obesity or there is a secondary cause for obesity
* Uncontrolled cardiac arrhythmia
* Unstable angina

Primary outcomes:
measure: Symptom-Limited Stair-Climbing Test(SLSCT)
timeFrame: baseline
measure: Six-Minute Walk Test(6MWT)
timeFrame: baseline
measure: Cardiopulmonary Exercise Test(CPET)
timeFrame: baseline
Secondary outcomes:
measure: Heart Rate
timeFrame: immediately after the procedure
measure: Left Ventricular Ejection Fraction
timeFrame: baseline
measure: Blood Pressure
timeFrame: immediately after the procedure
Other outcomes:
measure: FVC l/sec
timeFrame: baseline
measure: FEF 25-75 l/sec
timeFrame: baseline
measure: PEF l/sec
timeFrame: baseline
measure: FEV1 %
timeFrame: baseline
measure: FVC %
timeFrame: baseline
measure: FEF 25-75 %
timeFrame: baseline
measure: PEF %
timeFrame: baseline
measure: FEV1 l/sec
timeFrame: bseline
measure: FEV1/FVC
timeFrame: bseline
Locations:
Study officials:
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