Clinical trial NCT06704243: Peer Support Group for Adolescent and Young Adult (AYA) Allogeneic Stem Cell Transplant Recipients
Official title: Peer Support Group for AYA Allogeneic Stem Cell Transplant Recipients
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Cancer
Leukemia
Stem Cell Transplant
Keywords: peer support
adolescents and young adults
Lead sponsor: University Health Network, Toronto
Sponsor class: OTHER
First posted: 2024-11-26
Enrollment: 15
Sex: ALL
Minimum age (years): 18
Maximum age (years): 39
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: SUPPORTIVE_CARE

Brief summary: Allogeneic Haemopoietic Stem Cell Transplant (Allo-HSCT) is a potentially curative option for patients with both malignant and non-malignant hematological disorders. There appears to be unique experiences that adolescents and young adults (AYA) face when undergoing transplant. There is literature to suggest that peer support for young adults is associated with improvements in mental health including greater happiness, self-esteem and effective coping, as well as reductions in depression, loneliness and anxiety.

Our primary objective is to determine the feasibility and acceptability of an AYA peer support program for patients undergoing Allo-HSCT. Our secondary objective is to explore the impact of the AYA peer support program on sense of support/connectivity, anxiety, and depression.


Eligibility criteria: Inclusion Criteria:

* 18-39 years of age
* \>3 months post Allo-HSCT
* any malignant /non-malignant indication for Allo-HSCT

Exclusion Criteria:

- Non-English speaking

Primary outcomes:
measure: Feasibility of Intervention Measure (FIM)
timeFrame: at 6 months
measure: Acceptability of Intervention Measure (AIM)
timeFrame: at 6 months
measure: Intervention Appropriateness Measure (IAM)
timeFrame: at 6 months
measure: Post-intervention Qualitative interviews
timeFrame: at 6 months
measure: Intervention usage
timeFrame: at 6 months
Secondary outcomes:
measure: Social Connectedness
timeFrame: Baseline, 3 months, and 6 months
measure: Anxiety
timeFrame: Baseline, 3 months, and 6 months
measure: Depressive Symptoms
timeFrame: Baseline, 3 months, and 6 months
Other outcomes:
Locations:
city: Toronto
country: Canada
facility: Princess Margaret Cancer Centre
state: Ontario
Study officials:
affiliation: University Health Network, Toronto
name: Samantha Mayo, RN PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Spitzer RL, Kroenke K, Williams JB, Lowe B. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7. doi: 10.1001/archinte.166.10.1092.
citation: Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.
citation: Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. doi: 10.1046/j.1525-1497.2001.016009606.x.
citation: Lee, R. M., Robbins, S. B., & Hill, C. E. (1995). Measuring Belongingness: The Social Connectedness and the Social Assurance Scales. Journal of Counseling Psychology, 42(2), 232-241. https://doi.org/10.1037/0022-0167.42.2.232