Clinical trial NCT03081403: Quantitative Sensory Testing in Subjects With Sensitive Skin or Not
Official title: Quantitative Sensory Testing in Subjects With Sensitive Skin or Not
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Sensitive Skin
Keywords: Sensitive skin
Quantitative Sensory Testing
Lead sponsor: University Hospital, Brest
Sponsor class: OTHER
First posted: 2017-03-16
Enrollment: 42
Sex: ALL
Minimum age (years): 20
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Detailed description: Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Eligibility criteria: Inclusion Criteria:

* Age: between 20 and 60 years
* Cooperating patient
* Informed and written consent of the subject
* Affiliated to the social security
* For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

- To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion Criteria:

* Adults subject with legal protection
* Subject in a social institution.
* Subject with major cognitive or psychiatric disorders
* Subject with pathological use of alcohol or consumption of another drug.
* Subject with skin involvement of the back of the dominant hand or malformation.
* Known sensitive neuropathy
* Pregnant woman
* Subject receiving medical treatment which may interfere with the results.
* Subject with treatment in the back of the dominant hand.

Primary outcomes:
measure: Cutaneous perception threshold
timeFrame: 6 months
Secondary outcomes:
measure: The cutaneous perception threshold of vibration
timeFrame: 6 months
measure: The cutaneous perception threshold of cold
timeFrame: 6 months
Other outcomes:
Locations:
city: Brest
country: France
facility: CHRU de Brest
Study officials:
References: