Clinical trial NCT05688748: Effectiveness Evaluation of a Dengue Self-monitoring System
Official title: Effectiveness Evaluation of a Dengue Self-monitoring System (DeSMoS) to Reduce Treatment Delay in Malaysia
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Dengue
Keywords: dengue
outpatient care
self-monitoring system
treatment delay
warning symptoms
Lead sponsor: University of Malaya
Sponsor class: OTHER
Collaborators: name: Ministry of Health, Malaysia
First posted: 2023-01-18
Enrollment: 37
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The goal of this clinical trial is to compare the effectiveness of a dengue self-monitoring system with standard care in reducing treatment delay among dengue patients receiving outpatient care. The main question it aims to answer are:

• Is a dengue self-monitoring system effective in reducing treatment delay in dengue patients? Participants will use the dengue monitoring system in addition to the standard care they are receiving for outpatient follow up for dengue.

Researchers will compare them with dengue patients receiving the usual standard care to see if the dengue monitoring system reduces delay in treatment seeking in patients.

Detailed description: Dengue Self-Monitoring System (DeSMoS) was developed to guide patients about warning signs and advise them to visit a doctor appropriately before their scheduled follow up on the next day, apart from motivating them to comply to the daily follow up visits at the clinic. DeSMoS is hypothesised to effectively reduce delay in treatment seeking in dengue patients.

The main aim of this system is to get dengue patients to key-in their symptoms regularly via the app when they are at home. Reminders will appear on the phone to remind them to key in the symptoms thrice daily.

The system is designed as a supportive tool for outpatient dengue management. It is not meant to replace to usual standard care for dengue care.

Eligibility criteria: Inclusion Criteria:

* Age 18 years old and above
* Newly diagnosed with dengue fever
* Have a smartphone
* Receiving outpatient follow up for dengue

Exclusion Criteria:

* Hearing and speech impairment
* Cognitive impairment

Primary outcomes:
measure: Reduction in treatment delay
timeFrame: Up to two weeks
Secondary outcomes:
measure: Compliance to follow up
timeFrame: Up to two weeks
measure: Development of warning symptoms
timeFrame: Up to two weeks
measure: Hospitalization
timeFrame: Up to two weeks
Other outcomes:
Locations:
city: Shah Alam
country: Malaysia
facility: Klinik Kesihatan Seksyen 7 Shah Alam
state: Selangor
Study officials:
affiliation: University of Malaya
name: Wei Leik Ng
role: PRINCIPAL_INVESTIGATOR
References:
citation: Leo YS, Gan VC, Ng EL, Hao Y, Ng LC, Pok KY, Dimatatac F, Go CJ, Lye DC. Utility of warning signs in guiding admission and predicting severe disease in adult dengue. BMC Infect Dis. 2013 Oct 24;13:498. doi: 10.1186/1471-2334-13-498.
citation: Herbuela VRDM, Karita T, Francisco ME, Watanabe K. An Integrated mHealth App for Dengue Reporting and Mapping, Health Communication, and Behavior Modification: Development and Assessment of Mozzify. JMIR Form Res. 2020 Jan 8;4(1):e16424. doi: 10.2196/16424.