Clinical trial NCT05286125: Erector Spinae Plane Block Versus Oblique Subcostal Transverses Abdominis Plane Block
Official title: Erector Spinae Plane Block Versus Oblique Subcostal Transverses Abdominis Plane Block for Controlling Postoperative Pain After Umbilical Hernia Repair
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Postoperative Pain
Lead sponsor: Zagazig University
Sponsor class: OTHER_GOV
First posted: 2022-03-18
Enrollment: 52
Sex: ALL
Minimum age (years): 21
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: PREVENTION

Brief summary: Comparing the impact of bilateral erector spinae plane block and transverse abdominis plane block on improving quality of pain management after umbilical hernia repair.

Detailed description: Postoperative pain is an important problem after umbilical hernia repair which has negative effects on patient's hemodynamics and cause delayed ambulation resulting in prolonged duration of hospital stay and poor patient satisfaction.

Multiple analgesic strategies have been proposed including Non steroidal anti-inflammatory drugs (NSAIDs), opioids, epidural analgesia. Each of them has its limitations.

Ultra¬sound guided regional anesthesia techniques for abdominal wall can be effective components of multimodal postoperative analgesia with limited side-effects Erector spinae plane (ESP) block is a promising para-spinal bock that can achieve both visceral and somatic abdominal analgesia if the injection was performed at a lower thoracic level. Transverse abdominis plane (TAP) block which is considered a peripheral nerve block that is aimed at anesthetizing nerves supplying the anterior abdominal wall.

We will compare between erector spinae plane block and transverse abdominis plane block for controlling postoperative pain after umbilical hernia repair.

Patients will be allocated randomly into two equal groups by a computer-generated randomization table Group (E) (n=26): Patients will receive erector spinae plane (ESP) block after completion of surgery.

Group (T) (n= 26): Patients will receive oblique subcostal transverse abdominis plane (TAP) block after completion of surgery

Eligibility criteria: Inclusion Criteria:

* Patients scheduled for elective umbilical hernia repair.
* Patient acceptance.
* Both sex
* Patient's age 21 - 60 years.
* Patients with American Society of Anesthesiologists (ASA) physical status I, II.
* BMI 25 - 30 kg m-2.

Exclusion Criteria:

* Uncooperative patients and patients with psychological problems.
* Patients with liver or renal impairment.
* Patients with contraindication to regional anesthesia.
* Patients with history of allergy to drug used in the study.
* Patients with chronic pain.

Primary outcomes:
measure: Postoperative analgesic requirements
timeFrame: 24 hours postoperative
Secondary outcomes:
measure: Postoperative pain severity using Visual Analogue scale
timeFrame: 24 hours postoperative
measure: Postoperative pain severity using Verbal Rating Scale
timeFrame: 24 hours postoperative
measure: Postoperative pain severity using Numeric Rating Scale
timeFrame: 24 hours postoperative
measure: Postoperative heart rate changes
timeFrame: 24 hours postoperative
measure: Postoperative blood pressure changes
timeFrame: 24 hours postoperative
measure: Incidence of postoperative side effects
timeFrame: 24 hours postoperative
measure: Duration of postoperative hospital stay
timeFrame: 24 hours postoperative
Other outcomes:
Locations:
city: Zagazig
country: Egypt
facility: Zagazig University hospital
state: Sharkia
Study officials:
affiliation: Zagazig University
name: Michael A shaker, lecturer
role: PRINCIPAL_INVESTIGATOR
References: