Clinical trial NCT03846440: Inadequate Protein Intake at Specific Meals and Functionality in Middle to Older Aged Mexican Adults
Official title: Inadequate Protein Intake at Specific Meals and Functionality in Middle to Older Aged Mexican Adults
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Aging
Keywords: Protein intake
Older adults
Mexican adults
Functionality
Lead sponsor: Centro Universitario de Ciencias de la Salud, Mexico
Sponsor class: OTHER
Collaborators: name: Hospital General de Occidente
First posted: 2019-02-19
Enrollment: 190
Sex: ALL
Minimum age (years): 50
Maximum age (years): 95
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Middle to older aged Mexican adults attending to the Geriatrics Department at the Western General Hospital (Hospital General de Occidente) for their usual medical screening or first time assessment.

Brief summary: This study sought to determine if the inadequate protein intake per meal (defined as eating \<30 g protein or 0.4 g protein/kg body mass) at specific meals (breakfast, lunch, dinner) is associated with functionality in middle to older aged Mexican adults. Functionality was evaluated with self-reported questionnaires to assess their functionality score for different activities of daily living.

Detailed description: Detailed dietary information was obtained for each participant to estimate dietary protein intake per meal (breakfast, lunch, dinner). One meal was considered with inadequate protein intake if its content was \<30 g or 0.4 g/kg.

Functionality was assessed with two validated questionnaires. One for instrumental activities of daily living (Lawton) and another for activities of daily living (Barthel). We calculated a score according to each author's scales. This score was divided into three possible groups as "low", "middle", and "high" scores.

To analyze the association between inadequate protein intake per meal and functionality, we used multinomial logistic regression. The outcome variable was functionality ("High" was the reference group, "middle" and "low" scores were considered as impaired functionality), and the predictive variables were inadequate protein intake at breakfast, lunch, and dinner. They were adjusted for age, BMI categories, number of diagnosed diseases, sex, and inadequate protein intake per day (\<1.2 g/kg/d).

Eligibility criteria: Inclusion Criteria:

* Subjects able to stand up and walk independently or with walking sticks only.
* Subjects able to answer questionnaires independently or with minimum caregivers' assistance.

Exclusion Criteria:

* Subjects reporting any kind of hospitalization within the last year.

Primary outcomes:
measure: Functionality on Instrumental Activities of Daily Living
timeFrame: One day
measure: Functionality on Activities of Daily Living
timeFrame: One day
Secondary outcomes:
Other outcomes:
Locations:
city: Guadalajara
country: Mexico
facility: Instituto de Ciencias Aplicadas a la Actividad Física y al Deporte
state: Jalisco
Study officials:
affiliation: University of Guadalajara
name: Alejandro Gaytán-González
role: PRINCIPAL_INVESTIGATOR
References: