Clinical trial NCT05993494: Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals with Temporomandibular Dysfunction
Official title: Investigation of the Relationship Between Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals with Temporomandibular Dysfunction
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Temporomandibular Joint Disorders
Pain
Keywords: Temporomandibular Joint Dysfunction
Pain
central sensitization
kinesiophobia
stress
Lead sponsor: Karadeniz Technical University
Sponsor class: OTHER
First posted: 2023-08-15
Enrollment: 90
Sex: ALL
Minimum age (years): 18
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: -Patients diagnosed with Temporomandibular joint disorders

Brief summary: Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Recent research has focused specifically on pain catastrophe, kinesiophobia, and central sensitization in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction.

Detailed description: Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Psychological factors are stated as comorbid in individuals with TMD. Individuals with TMD-related pain show higher levels of stress, anxiety, depression, somatic awareness, pain catastrophizing, and kinesiophobia compared to controls. Therefore, recent research has focused on pain catastrophe, kinesiophobia, and central sensitization, especially in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction. Ninety patients aged 18-65 years, who have TME-related complaints for at least 3 months, and diagnosed with TMD as a result of clinical and radiological evaluation by a dentist will be included in the study.

Eligibility criteria: Inclusion Criteria:

* Between the ages of 18-65,
* Having complaints related to TMJ for at least 3 months,
* Patients diagnosed with TMD as a result of clinical and radiological evaluation by the dentist

Exclusion Criteria:

* Cognitive problems,
* Any systemic joint or muscle disease (e.g. fibromyalgia, rheumatoid arthritis),
* Serious systemic diseases,
* Any neurological disorder (e.g. trigeminal neuralgia),
* Pregnancy, breastfeeding status,
* Previous treatment for TMJ or orofacial muscle pain

Primary outcomes:
measure: Numeric Pain Scale
timeFrame: through study completion, an average of 1 year
measure: Tampa Scale for Kinesiophobia
timeFrame: through study completion, an average of 1 year
measure: Perceived Stress Scale
timeFrame: through study completion, an average of 1 year
measure: Central sensitization scale
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Trabzon
country: Turkey
facility: Karadeniz Technical University
Study officials:
affiliation: Karadeniz Technical University
name: Nurhayat Korkmaz
role: PRINCIPAL_INVESTIGATOR
References: