Clinical trial NCT03186820: Exploratory Study of the Interest of MRI Susceptibility Weighted Imaging for the Pre-operative Assessment of Pelvic Endometriosis Extent
Official title: Exploratory Study of the Interest of MRI Susceptibility Weighted Imaging for the Pre-operative Assessment of Pelvic Endometriosis Extent
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Endometriosis
Keywords: Endometriosis
Magnetic resonance imaging (MRI)
Susceptibility-weighted imaging (SWI)
Lead sponsor: University Hospital, Bordeaux
Sponsor class: OTHER
First posted: 2017-06-14
Enrollment: 74
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Prospective monocentric comparative study
Primary purpose: PREVENTION

Brief summary: Knowledge of the precise location of endometriosis is essential for a successful surgical treatment. MRI Susceptibility-Weighted Imaging (SWI-MRI) yields high sensitivity for blood by-products detection. Since endometriosis lesions are haemorrhagic, and therefore rich in blood by-products such as hemosiderin, SWI-MRI could be useful in the pre-operative assessment of endometriosis, especially in superficial peritoneal lesion detection. The purpose of our study is to evaluate the performance of SWI-MRI for the preoperative work-up of endometriosis

Detailed description: Pelvic endometriosis is a cause of pelvic pain, dysmenorrhea, urinary symptoms and infertility. MRI is considered as the best imaging technique to detect and to predict the extent of the disease. Susceptibility Weighted Imaging is routinely performed to identify haemorrhagic lesions in brain MRI protocols and has proven to be a sensitive technique to detect blood by-products. A pelvic MRI protocol including SWI will be performed in all women addressed for diagnostic assessment or pre-operative work-up of endometriosis.

Eligibility criteria: Inclusion Criteria:

* Adult woman (over 18yrs old) addressed for diagnostic assessment or pre-operative work-up of endometriosis;
* Informed signed consent
* Affiliated or beneficiary of a social security system

Exclusion Criteria:

* Patient \<18yrs old
* Pregnant or nursing woman
* Patient under legal protection
* Contraindication to MRI

Primary outcomes:
measure: Interest of MRI Susceptibility Weighted Imaging
timeFrame: Baseline (MRI) and day of surgery
Secondary outcomes:
measure: Deep forms of endometriosis
timeFrame: Baseline (MRI) and day of surgery
measure: Superficial forms of endometriosis
timeFrame: Baseline (MRI) and day of surgery
Other outcomes:
Locations:
city: Bordeaux
country: France
facility: CHU de Bordeaux
Study officials:
References:
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