Clinical trial NCT04639765: Responses to Information on Treatments for Depression
Official title: Responses to Information on Treatments for Depression
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Depressive Symptoms
Keywords: depression
treatment preference
treatment information
Lead sponsor: Ohio State University
Sponsor class: OTHER
First posted: 2020-11-20
Enrollment: 300
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: The purpose of this study is to determine the impact of different messages about depression treatments.

Detailed description: Participants recruited through Amazon Mechanical Turk (MTurk) will complete a screening questionnaire and provided the opportunity to consent to participate. Upon entry to the study, eligible participants will complete several questionnaires pre- and post-randomization. Randomization will be to view either a video detailing a type of depression treatment (cognitive behavioral therapy, antidepressant medication, or the combination of both treatments) with and without an emphasis on personalization. A no video condition is also included.

Eligibility criteria: Inclusion Criteria:

* PHQ-9 Score indicating a history of elevated depression symptoms
* A high MTurk completion rate
* Must pass all attention checks inserted into the questionnaires
* No history of treatment for depression

Exclusion Criteria:

* none

Primary outcomes:
measure: Regressed change from baseline in expectations on the Credibility/Expectancy Questionnaire (CEQ)
timeFrame: Up to 90 minutes to complete assessment. Assessed immediately pre- and post-intervention (on the same day)
measure: Regressed change from baseline in prognostic pessimism on an adapted version of the Perceptions of Depression Scale (PDS)
timeFrame: Up to 90 minutes to complete assessment. Assessed immediately pre- and post-intervention (on the same day)
Secondary outcomes:
measure: Regressed change from baseline in affect on the Positive and Negative Affectivity Scale (PANAS)
timeFrame: Up to 90 minutes to complete assessment. Assessed immediately pre- and post-intervention (on the same day)
measure: Regressed Change from baseline on the Beck Hopelessness Scale (BHS)
timeFrame: Up to 90 minutes to complete assessment. Assessed immediately pre- and post-intervention (on the same day)
measure: Regressed change from baseline in personal and perceived depression stigma on the Depression Stigma Scale (DSS).
timeFrame: Up to 90 minutes to complete assessment. Assessed immediately pre- and post-intervention (on the same day)
measure: Regressed change from baseline in beliefs on the etiology of depression on the Reasons for Depression Questionnaire (RFD).
timeFrame: Up to 90 minutes to complete assessment. Assessed immediately pre- and post-intervention (on the same day)
measure: Willingness to take a next step.
timeFrame: Up to 90 minutes to complete assessment. Assessed at the end of the study questionnaires (same day)
Other outcomes:
Locations:
city: Columbus
country: United States
facility: Psychology Building 1835 Neil Avenue
state: Ohio
Study officials:
affiliation: Professor
name: Daniel Strunk, PhD
role: PRINCIPAL_INVESTIGATOR
References: