Clinical trial NCT04481074: Inspiratory Muscle Training in Patients With Interstitial Lung Disease
Official title: Effects of Inspiratory Muscle Training in Inspiratory Muscle Endurance, Breathlessness, Inspiratory Muscle Strength, Functional Capacity and Quality of Life in Patients With Interstitial Lung Disease
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Interstitial Fibrosis
Pulmonary Disease
Interstitial Lung Disease
Sarcoidosis
Idiopathic Pulmonary Fibrosis
Pneumonia, Interstitial
Keywords: Inspiratory muscle training
Interstitial lung disease
Inspiratory muscle endurance
Breathless
Lead sponsor: Federal University of Minas Gerais
Sponsor class: OTHER
Collaborators: name: Conselho Nacional de Desenvolvimento Científico e Tecnológico
name: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
First posted: 2020-07-22
Enrollment: 14
Sex: ALL
Minimum age (years): 40
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: Quasi-experimental
Primary purpose: OTHER

Brief summary: The aim of this study is to evaluate the effects of inspiratory muscle training program in inspiratory muscle endurance, breathlessness, inspiratory muscle strength, functional capacity and quality of life in patients with interstitial lung disease. Patients are evaluated before the inspiratory muscle training and after 8 weeks of training.

Detailed description: Inspiratory Muscle Training has been described as an effective intervention and contribute to the improvement of inspiratory muscle function and breathlessness in patients with chronic lung disease. The aim of this study is to evaluate, the effects of inspiratory muscle endurance, breathlessness, inspiratory muscle strength, functional capacity and quality of life in patients with interstitial lung disease. It is a quasi-experimental study. Patients with interstitial lung disease are recruited from interstitial disease ambulatory. In each session patients performs two times 30 breaths with a minute rest between them. The load is set according with 50% of actual PImax, the Borg score should be between 4 and 6, otherwise the load will decrease (if Borg more than 6) or increase (if Borg less than 4). New PImax is measured weekly and the new load is defined following the same protocol for 8 weeks. Patients are evaluated before the inspiratory muscle training and after 8 weeks of training.

Eligibility criteria: Inclusion Criteria:

* Clinical and radiological diagnosis of interstitial lung disease established by a pulmonologist;
* Absence of clinical exacerbations of the disease in the four weeks prior to the initial data collection;
* Present medical research council scale more than 2;
* Absence of a associated or self reported cardiac, orthopedic and psychiatric diseases,
* Not participating in pulmonary rehabilitation programs;
* Do not use supplemental oxygen therapy while resting.

Exclusion Criteria:

- Inability of the participant to understand or perform the procedures proposed during the evaluations and training program.

Primary outcomes:
measure: Change in Inspiratory muscle endurance
timeFrame: At baseline and after 8 weeks of training
measure: Change in Breathlessness
timeFrame: At baseline and after 8 weeks of training
Secondary outcomes:
measure: Change in Inspiratory muscle strength
timeFrame: At baseline and after 8 weeks of training
measure: Change in Functional capacity
timeFrame: At baseline and after 8 weeks of training
measure: Change in Quality of life
timeFrame: At baseline and after 8 weeks of training
Other outcomes:
Locations:
city: Belo Horizonte
country: Brazil
facility: Ambulatório Bias Fortes - Ambulatório de Doenças Intersticiais do Hospital das Clínicas da Universidade Federal de Minas Gerais.
state: Minas Gerais
city: Belo Horizonte
country: Brazil
facility: Laboratório de Avaliação e Pesquisa em Desempenho Cardiorrespiratório da UFMG
state: Minas Gerais
Study officials:
References: