Clinical trial NCT05084820: Action Observation Treatment on Motor Function in Upper Limb of Patients With Chronic Stroke
Official title: Effects of Action Observation Treatment on Motor Function in Upper Limb of Patients With Chronic Stroke
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Keywords: stroke
action observation treatment
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-10-20
Enrollment: 14
Sex: ALL
Minimum age (years): 50
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: each participant will be requested to draw either number one or two from a box.number one refers to group A and number two refers to group B. Group A patients will receive conventional treatment of 40 minutes in total. group B is experimental group , patients will watch videos of 5 common motor tasks that implicit the usage of items to be used for action observation treatment.
Primary purpose: TREATMENT

Brief summary: To determine the effects of action observation treatment on motor functions in upper limb of patients with chronic stroke

Detailed description: Stroke is one of the major cause of death in Pakistan and also a prime source of disability in older adults.Mirror neuron system depends on motor regions, and its dominant aspect is that,it is activated for implementation of motor activity and also for its observation. This "dual activation" characteristic of mirror neuron helps in improving the observation and execution of different actions.

aim of this study is to determine the effects of action observation treatment on motor function in upper limb of patients with chronic stroke.

An RCT will be conducted on 14 chronic stroke patients from Omar Hospital and Riphah Rehabilitation Centre Lahore. Patients will be randomly allocated into control group (n=7) and Experimental group (n=7) by lottery method. Control group will be given only conventional treatment that included stretching, strengthening, pinching, gripping, reaching and grasping exercises, while Experimental group received conventional treatment and action observation treatment 3 days/ week for 4 weeks. Treatment outcomes will be assessed on Modified Barthel Index and Fugl-Meyer Assessment for upper extremity (FMA-UE)

Eligibility criteria: Inclusion Criteria:

* Chronic Stroke patients (with more than 6 months- 4 years) illness
* Patients that were able to communicate and comprehend oral instructions
* Patients with Mini Mental State Examination (MMSE) score more than 24

Exclusion Criteria:

* Patients having psychiatric histories.
* Visual and hearing impaired patients
* Patients with speech impairment
* Patients with arthritic deformities in upper limb (with or without using assistive device)
* Patients with diagnosed mental illness.

Primary outcomes:
measure: modified barthal index
timeFrame: 40 minutes
measure: Fugl-Meyer Assessment test
timeFrame: 40 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Riphah international university
state: Fedral
Study officials:
affiliation: Riphah International University
name: zeest hashmi, MS NMPT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Mao H, Li Y, Tang L, Chen Y, Ni J, Liu L, Shan C. Effects of mirror neuron system-based training on rehabilitation of stroke patients. Brain Behav. 2020 Aug;10(8):e01729. doi: 10.1002/brb3.1729. Epub 2020 Jul 1.
citation: Keller J, Stetkarova I, Macri V, Kuhn S, Petioky J, Gualeni S, Simmons capital ES, CyrillicD, Arthanat S, Zilber P. Virtual reality-based treatment for regaining upper extremity function induces cortex grey matter changes in persons with acquired brain injury. J Neuroeng Rehabil. 2020 Sep 12;17(1):127. doi: 10.1186/s12984-020-00754-7.
citation: Keci A, Tani K, Xhema J. Role of Rehabilitation in Neural Plasticity. Open Access Maced J Med Sci. 2019 May 14;7(9):1540-1547. doi: 10.3889/oamjms.2019.295. eCollection 2019 May 15.
citation: Habibi-Koolaee M, Shahmoradi L, Niakan Kalhori SR, Ghannadan H, Younesi E. Prevalence of Stroke Risk Factors and Their Distribution Based on Stroke Subtypes in Gorgan: A Retrospective Hospital-Based Study-2015-2016. Neurol Res Int. 2018 Jul 26;2018:2709654. doi: 10.1155/2018/2709654. eCollection 2018.