Clinical trial NCT05848076: Effects of Therapeutic Neuroscience Education in Patients With Chronic Low Back Pain
Official title: Effects of Therapeutic Neuroscience Education on Nociplastic Pain and Disability in Patients With Chronic Low Back Pain
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Chronic Low-back Pain
Keywords: back pain
therapuetic neuroscience education
range of motion
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-05-08
Enrollment: 22
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: blinding
Primary purpose: TREATMENT

Brief summary: The study will be Randomized controlled trail, Subject diagnosed with low back pain meeting predetermined inclusion and exclusion criteria will be divided into two groups.

Pre assessment will be done using pain and disability as subjective measurement through Numeric pain rating scale (NPRS) \& modified Oswestry disability index and the lumber range by goniometer as objective measurement. One group is subject will be treated with therapeutic neuroscience education and core stability exercise and second group is core stability exercise. Each subject received 18 sessions with 3 treatments per week. Post treatment values recorded after the session.After data collection from defined study setting,data will be entered and analyzed at Riphah International University,Lahore

Detailed description: Chronic low back pain (LBP) is very common musculoskeletal disorders and leading causes of disability worldwide. Numerous epidemiological data show that 11%-84% of people experience, have experienced,or will experience pain in the lower spine at least once in their lives . With a global prevalence of 9.4%, LBP was ranked highest in the number of years lived with a disability and sixth in overall burden of disease Pakistan can suffer 56% from the LBP Nociplastic pain can be mechanistically defined as pain arising from the altered function of pain-related sensory pathways in the periphery and CNS, causing increased sensitivity Nociplastic pain should be viewed as an overarching terminology that can be applied to a diverse range of clinical conditions that share common neurophysiological mechanisms.

The main concern of TNE concept is that increasing the patient feeling of biology and physiology underpinning their pain condition instead of focus on anatomy and structure issues of tissue.In order to improve health of patient with CLBP healthcare provider proper educate their patient about experiencing pain and it may not result of tissue damage Several non surgical treatments have been offered to help and decrease LBP, such as joint manipulation, traditional therapeutic exercises , and medication

core stability training (CST) program this type of exercise focuses on the ability of the spine to stabilize in different positions and emphasize smaller, deeper, and posterior muscles. By increasing the endurance of these muscles, they retrain and maintain the correct physical condition to stabilize the spine to improve pain, performance, and ROM

There are few studies in literature which compare the TNE effect with core stability exercisein CLBP however there have been no studies which can compare TNE with nociplastic pain which effects on CLBP

Eligibility criteria: Inclusion Criteria:

* Diffused chronic low back pain
* Stop movement due to fear of increasing pain
* Anxiety and sleep problem with CLBP
* Symptoms duration most of days in 6 months
* No treatment other than analgesics

Exclusion Criteria:

* Diabetes mellites
* Radiating pain
* Spine surgery, fracture, arthritis

Primary outcomes:
measure: Numeric pain rating scale for pain
timeFrame: 3 weeks
measure: Modified Oswestry Disability index (Disability and function)
timeFrame: 3 weeks
Secondary outcomes:
measure: Goniometer (Range of Motion)
timeFrame: 3 weeks
Other outcomes:
Locations:
city: Layyah
country: Pakistan
facility: District Headquarter Hospital Layyah
state: Punjab
Study officials:
affiliation: Study Principal Investigator
name: Muhammad Sanaullah, MS
role: PRINCIPAL_INVESTIGATOR
affiliation: Study Principle Investigator
name: Ume Habiba
role: PRINCIPAL_INVESTIGATOR
References: