Clinical trial NCT05225766: Comparison of Erector Spinae Plane Block and Rectus Sheath Block
Official title: Comparison of Intraoperative and Postoperative Effects of Erector Spinae Plane Block and Rectus Sheath Block
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Postoperative Pain, Acute
Keywords: erector spinae plane block
rectus sheath block
pain management
midline laparotomy
Lead sponsor: Uludag University
Sponsor class: OTHER
First posted: 2022-02-07
Enrollment: 60
Sex: ALL
Minimum age (years): 18
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: In study, The investigators aimed to compare the intraoperative and postoperative analgesic efficacy of erector spinae plane block and rectus sheath block, which investigators routinely perform in surgeries with abdominal lover midline-upper midline incision, morphine consumption with patient-controlled analgesia, as well as patient and surgeon satisfaction.

Detailed description: Following ethics committee approval and written consent from the patients, the study was conducted on 60 patients aged between 18-75 years in American Society of Anesthesiologists (ASA) classes I-III, who were to undergo midline incisions. The demographic data of the patients were recorded and after routine monitoring and general anesthesia induction, they were divided into two groups as the ESPB group and RSB group. Hemodynamic data of all patients were recorded before induction, one minute after induction, and intraoperatively in 30-minute periods. Patient-controlled analgesia (PCA) prepared with morphine was administered to all patients. Patients' intraoperative hemodynamic data and administered opioid doses, postoperative visual analog scales (VAS) at rest and during coughing, time to first PCA dose, postoperative morphine consumption, need for rescue analgesics, duration time until first mobilization, opioid side effects, and patient and surgeon satisfaction were evaluated.

Eligibility criteria: Inclusion Criteria:

* Aged 18-75 years
* American Society of Anesthesiologists (ASA) classes I-III

Exclusion Criteria:

* Local anesthetic allergy
* Coagulopathy
* Injection site infection
* History of abdominal surgery
* Severe neurological or psychiatric disorder
* Severe cardiovascular disease, liver failure, renal failure (glomerular filtration rate \<15 ml/min/1.73 m2)
* chronic opioid use

Primary outcomes:
measure: intraoperative hemodynamic data and administered opioid doses
timeFrame: 150 minutes
measure: postoperative visual analog scales at rest and during coughing
timeFrame: 48 hours
measure: time to first patient controlled analgesia (PCA) dose
timeFrame: 48 hours
measure: postoperative morphine consumption
timeFrame: 48 hours
measure: need for rescue analgesics
timeFrame: 48 hours
measure: duration time until first mobilization
timeFrame: 48 hours
measure: opioid side effects
timeFrame: 48 hours
measure: patient and surgeon satisfaction
timeFrame: 48 hours
Secondary outcomes:
Other outcomes:
Locations:
city: Bursa
country: Turkey
facility: Bursa Uludag University
state: Nilüfer
Study officials:
affiliation: Investigator
name: Emre SALMAN, MD
role: PRINCIPAL_INVESTIGATOR
References: