Clinical trial NCT04462731: Post-endodontic Pain Survey
Official title: Postoperative Pain After One-visit Root Canal Treatment on Teeth With Vital Pulps: Comparison of Two Different Root Filling Techniques
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Postoperative Pain
Endodontic Disease
Obturation
Keywords: Postoperative Pain
Bioceramic
Root canal filling
Lead sponsor: University of Pennsylvania
Sponsor class: OTHER
First posted: 2020-07-08
Enrollment: 194
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Non-surgical root canal treatment:

All teeth were isolated with a rubber dam during root canal treatment. The procedures were performed under a microscope (OPMI Pico; Carl Zeiss, Gottingen, Germany). After access, location of canals, and determination of working length (WL) with Root ZX II apex locator (J Morita, Kyoto, Japan), the canals were instrumented using various .04 taper rotary NiTi instruments to a minimum apical size of 35. 4% NaOCl was used as the main irrigant. 17% EDTA was used as the final irrigant. Passive ultrasonic irrigation with size 20 Acteon tip inserted 2mm short of WL was performed with both 4% NaOCl and 17% EDTA for 10 seconds in each canal. After final irrigation, the canals were dried with paper points. The master gutta-percha cone fit was verified with periapical radiographs before filling the tooth.
Primary purpose: TREATMENT

Brief summary: As part of root canal treatment, canals should be sealed to prevent further contaminations. There are multiple accepted techniques to fill-obturate canals. In the past, different obturation techniques have been compared. The most current technique used, a single cone with bioceramic sealer, has not been compared. This clinical investigation will compare the postoperative pain of this technique to another common technique used in our clinic. Postoperative pain after one-visit root-canal treatment on teeth with vital pulps: Comparison of three different obturation techniques.


Eligibility criteria: Inclusion Criteria:

* Diagnosis of asymptomatic or symptomatic irreversible pulpitis according to AAE consensus. The diagnosis was based on clinical examinations and confirmed upon accessing the teeth.
* Consenting adults age 18 years and older
* Non-contributory medical history (ASA Class I \& II)
* Included patients were given oral and written information agreed for participation and signed the informed consent

Exclusion Criteria:

* Non-consenting patients and patients below 18 years of age
* Medical history with ASA Class III \& IV
* Non-restorable teeth
* Teeth with a non-vital pulp
* Periodontal probing depths were more than 4mm
* Pre-medication with antibiotics and/or analgesics 24 hours before the treatment
* Patients taking analgesics routinely for non-dental reasons

Primary outcomes:
measure: Visual Analogue Scale (VAS)
timeFrame: 4-, 24-, and 48-hour after receiving root canal treatment
Secondary outcomes:
Other outcomes:
Locations:
Study officials:
References:
citation: Yu YH, Kushnir L, Kohli M, Karabucak B. Comparing the incidence of postoperative pain after root canal filling with warm vertical obturation with resin-based sealer and sealer-based obturation with calcium silicate-based sealer: a prospective clinical trial. Clin Oral Investig. 2021 Aug;25(8):5033-5042. doi: 10.1007/s00784-021-03814-x. Epub 2021 Feb 8.