Clinical trial NCT03942562: Temporal Relationship in Recovery of Muscular Pain and Functional Variables in an Experimental Muscular Pain Model in Hamstrings
Official title: Temporal Relationship in Recovery of Muscular Pain, Functional Variables and Normal Gait Pattern in an Experimental Muscular Pain Model in Hamstrings
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pain, Muscle
Keywords: DOMS
Healthy subjects
Pressure pain thresholds
Active Knee Extension test
Maximal strength
Electromyography
Plantar pressure measurement
Gait analysis
Lead sponsor: Universidad San Jorge
Sponsor class: OTHER
First posted: 2019-05-08
Enrollment: 24
Sex: MALE
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Non sedentary healthy men

Brief summary: Basal measurements are taken in relation to the study variables. Immediately subjects perform eccentric exercise on right hamstrings to develop delayed onset muscle soreness (DOMS).

Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Detailed description: Basal measurements are taken in relation to the study variables.

The variables are:

* pressure pain thresholds
* electromyography values
* static and dynamic plantar pressure measurement
* active knee extensibility
* maximal strength of knee flexors
* thermography
* scales of pain perception

Immediately subjects perform eccentric exercise on right hamstrings to develop DOMS (delay onset muscle soreness).

Measurements of the study variables are taken in the same conditions 48, 96 and 168 hours after the exercise to study the evolution of the variables while recovering from DOMS.

Eligibility criteria: Inclusion Criteria:

* not sedentary subject (IPAQ scale \> 600 MET)
* healthy subjects, without pain nor injury at the moment

Exclusion Criteria:

* subjects with acute or chronic pain on every spot of pelvis or lower limbs at the momento or for the last 3 months;
* subjects with history of severe injury in the hamstrings muscles;
* presence of serious illness;
* presence of pathologies in relation to chronic pain (as fibromyalgia, migraine disorders, non specific and chronic lumbar pain);
* not commitment for continuity in the study program;

Primary outcomes:
measure: Changes in spatio temporal parameters of gait
timeFrame: Baseline, 48 hours, 96 hours, 1 week
Secondary outcomes:
measure: Changes in Pressure Pain Thresholds
timeFrame: Baseline, 48 hours, 96 hours, 1 week
measure: Changes in active knee extension test
timeFrame: Baseline, 48 hours, 96 hours, 1 week
measure: Changes in knee-flexors maximal isometric muscle strength
timeFrame: Baseline, 48 hours, 96 hours, 1 week
measure: Electromyography (EMG) measurement during the tests
timeFrame: Baseline, 48 hours, 96 hours, 1 week
measure: Changes in thermography on hamstrings areas
timeFrame: Baseline, 48 hours, 96 hours, 1 week
measure: Changes in static and dynamic plantar pressure measurement
timeFrame: Baseline, 48 hours, 96 hours, 1 week
measure: Changes in subjective perception of pain and impairment: Two questionnaire (Modified 7-item Likert Scales)
timeFrame: 48 hours, 96 hours, 1 week
Other outcomes:
Locations:
city: Villanueva De Gállego
country: Spain
facility: Universidad San Jorge
state: Zaragoza
Study officials:
affiliation: Universidad San Jorge
name: Víctor Doménech, MSc
role: STUDY_DIRECTOR
References: