Clinical trial NCT06153030: Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
Official title: Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Diverticulitis, Colonic
Keywords: acute diverticulitis
right colon
emergency
pain
Lead sponsor: Haydarpasa Numune Training and Research Hospital
Sponsor class: OTHER
First posted: 2023-12-01
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients diagnosed with right colonic diverticulitis between the years of 2018-2022

Brief summary: BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked. Acute right colon diverticulitis is one of them. It is usually seen in male and young patients. It is more common in Asian population and rare in Western countries. Ultrasonography (USG) and computed tomography (CT) are used for radiologic diagnosis.

OBJECTIVES: The aim of this study was to investigate the diagnosis, treatment and surgical management of right colon diverticulitis.

Detailed description: DESIGN: Retrospective cross-sectional analysis SETTING: Research and training hospital (Tertiary care center) In our study, patients hospitalized in our hospital clinic between 2018 and 2022 with the diagnosis of right colon diverticulitis were retrospectively analyzed. Age, gender, WSES grade, whether surgery was performed or not, laboratory values, iv antibiotherapies given, length of hospitalization and mortality were evaluated.

MAIN OUTCOME MEASURES: The CRP, the need for surgical intervention vs conservative treatment .

Eligibility criteria: Inclusion Criteria:

* Patients diagnosed with right colonic diverticulitis

Exclusion Criteria:

* \<18 years of age

Primary outcomes:
measure: The need for surgical intervention
timeFrame: time frame is the length of stay usually between 1-14 days
Secondary outcomes:
Other outcomes:
Locations:
city: Üsküdar
country: Turkey
facility: Haydarpasa Numune Training and Research Hospital
state: Istanbul
Study officials:
References:
citation: Turner GA, O'Grady MJ, Purcell RV, Frizelle FA. The Epidemiology and Etiology of Right-Sided Colonic Diverticulosis: A Review. Ann Coloproctol. 2021 Aug;37(4):196-203. doi: 10.3393/ac.2021.00192.0027. Epub 2021 Jul 21.
citation: Papatriantafyllou A, Dedopoulou P, Soukouli K, Karioris I, Tsochatzis S. Right-Sided Diverticulitis: A Rare Cause of Right-Sided Abdominal Pain. Cureus. 2023 Apr 4;15(4):e37123. doi: 10.7759/cureus.37123. eCollection 2023 Apr.
citation: Ma Z, Liu W, Zhou J, Yao L, Xie W, Su M, Yang J, Shao J, Chen J. Management and long-term outcomes of acute right colonic diverticulitis and risk factors of recurrence. BMC Surg. 2022 Apr 7;22(1):132. doi: 10.1186/s12893-022-01578-z.
citation: Kahveci S, Tokmak TT, Yildirim A, Mavili E. Acute right-sided colonic diverticulitis mimicking appendicitis: a report of two cases. J Clin Ultrasound. 2013 May;41(4):238-41. doi: 10.1002/jcu.21967. Epub 2012 Aug 1.
citation: Shin JH, Son BH, Kim H. Clinically distinguishing between appendicitis and right-sided colonic diverticulitis at initial presentation. Yonsei Med J. 2007 Jun 30;48(3):511-6. doi: 10.3349/ymj.2007.48.3.511.
citation: Lee JH, Ahn BK, Lee KH. Conservative treatment of uncomplicated right-sided diverticulitis: a systematic review and meta-analysis. Int J Colorectal Dis. 2021 Aug;36(8):1791-1799. doi: 10.1007/s00384-021-03913-x. Epub 2021 Mar 25.
citation: Park SM, Kwon TS, Kim DJ, Lee YS, Cheung DY, Oh ST, Kim JG, Lee IK. Prediction and management of recurrent right colon diverticulitis. Int J Colorectal Dis. 2014 Nov;29(11):1355-60. doi: 10.1007/s00384-014-1938-3. Epub 2014 Jul 6.
citation: Park HC, Kim BS, Lee K, Kim MJ, Lee BH. Risk factors for recurrence of right colonic uncomplicated diverticulitis after first attack. Int J Colorectal Dis. 2014 Oct;29(10):1217-22. doi: 10.1007/s00384-014-1941-8. Epub 2014 Jul 1.
citation: Kim YC, Chung JW, Baek JH, Lee WS, Kim D, Park YH, Yang JY, Lee WK. Risk Factors for Recurrence of Right Colonic Diverticulitis. Dig Surg. 2019;36(6):509-513. doi: 10.1159/000494297. Epub 2018 Nov 8.
citation: Kim MR, Kye BH, Kim HJ, Cho HM, Oh ST, Kim JG. Treatment of right colonic diverticulitis: the role of nonoperative treatment. J Korean Soc Coloproctol. 2010 Dec;26(6):402-6. doi: 10.3393/jksc.2010.26.6.402. Epub 2010 Dec 31.
citation: Lee KY, Lee J, Park YY, Oh ST. Routine colonoscopy may be needed for uncomplicated acute right colonic diverticulitis. BMC Gastroenterol. 2021 Feb 27;21(1):91. doi: 10.1186/s12876-021-01672-1.
citation: Huang SS, Sung CW, Wang HP, Lien WC. The outcomes of right-sided and left-sided colonic diverticulitis following non-operative management: a systematic review and meta-analysis. World J Emerg Surg. 2022 Nov 1;17(1):56. doi: 10.1186/s13017-022-00463-7.
citation: Palacios Huatuco RM, Pantoja Pachajoa DA, Liano JE, Picon Molina HA, Palencia R, Doniquian AM, Parodi M. Right-sided acute diverticulitis in the West: experience at a university hospital in Argentina. Ann Coloproctol. 2023 Apr;39(2):123-130. doi: 10.3393/ac.2021.00402.0057. Epub 2021 Nov 24.
citation: Oh MY, Shin R, Heo SC, Lim HK, Kim MJ, Park JW, Ryoo SB, Jeong SY, Park KJ. Investigation of the clinical features and recurrence patterns of acute right-sided colonic diverticulitis: A retrospective cohort study. Ann Med Surg (Lond). 2022 Aug 18;81:104431. doi: 10.1016/j.amsu.2022.104431. eCollection 2022 Sep.
citation: Rov A, Ben-Ari A, Barlev E, Pelcman D, Susmalian S, Paran H. Right-sided diverticulitis in a Western population. Int J Colorectal Dis. 2022 Jun;37(6):1251-1256. doi: 10.1007/s00384-022-04135-5. Epub 2022 May 4.