Clinical trial NCT05065138: Comparison of Helicobacter Pylori Eradication Effect Before and After Training of Gastroenterologists
Official title: Comparison of the Effect of Helicobacter Pylori Eradication Before and After the Training of Gastroenterologists on Standardized Helicobacter Pylori Eradication Therapy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Helicobacter Pylori Infection
Keywords: Standardized training on Helicobacter pylori eradication
Gastroenterologist
Lead sponsor: Shandong University
Sponsor class: OTHER
First posted: 2021-10-01
Enrollment: 1025
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The researchers recruited gastroenterologists. Physician subjects recruited Helicobacter pylori-positive patients before and after receiving standardized training on Helicobacter pylori eradication. There are no restrictions on treatment options and drugs during the trial. Compare the eradication rate, adverse reaction rate, and patient compliance before and after physician training.

Detailed description: The researchers recruited no less than 20 gastroenterologists to participate in the study, and gastroenterologists recruited 25 patients who were over 18 years of age and were positive for Helicobacter pylori for the first time. In this process, the patient population is not restricted, and the eradication program is not restricted. Gastroenterologists followed up their diagnosis and treatment. Researchers track and record patients' medications and adverse reactions during medication via phone or WeChat to assess patient compliance. Record the eradication rate. The researchers will provide standardized Helicobacter pylori eradication training for the Department of Gastroenterology after all patients treated by gastroenterologists have been eradicated and reviewed. After the training, the gastroenterologist recruited 25 patients who were over 18 years old and were newly treated with Helicobacter pylori positive. In this process, the patient population is not restricted, and the eradication program is not restricted. Gastroenterologists followed up their diagnosis and treatment. Researchers track and record patients' medications and adverse reactions during medication via phone or WeChat to assess patient compliance. Record the eradication rate. Compare the eradication rate, adverse reaction rate and compliance of patients before and after the training of gastroenterologists.

Eligibility criteria: Inclusion Criteria:

* 1.Physician specialized in gastroenterology.
* 2.Diagnosis and treatment conditions for H. pylori exist in the hospital where the gastroenterology doctor is located.

(C13 urea breath test, C14 urea breath test, rapid urease test, stool H. pylori antigen test, histopathological test, H. pylori culture, any of the above)

Exclusion Criteria:

* 1.Those who are unable or unwilling to provide informed consent.
* 2.Patients with H. pylori have never been diagnosed and treated.

Primary outcomes:
measure: Eradication rate
timeFrame: 1 year
Secondary outcomes:
Other outcomes:
Locations:
city: Jinan
country: China
facility: Xiuli Zuo
state: Shandong
Study officials:
affiliation: Qilu Hospital of Shandong University
name: Xiuli Zuo, MD,PhD
role: PRINCIPAL_INVESTIGATOR
References: