Clinical trial NCT02384057: Cognitive Rehabilitation With C8 Sciences
Official title: Cognitive Rehabilitation for Participants With Stroke or Brain Injury Using C8 Sciences
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Stroke
Brain Injuries
Lead sponsor: National Rehabilitation Center, Seoul, Korea
Sponsor class: OTHER_GOV
Collaborators: name: Hanyang University
name: National IT Industry Promotion Agency, Republic of Korea
First posted: 2015-03-10
Enrollment: 31
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: C8 sciences program is a cognitive training program mainly developed for the students, and the effectiveness is well established. The aim of this trial is to assess clinical efficacy of the program for cognitive rehabilitation of the patients with stroke or brain injury.


Eligibility criteria: Inclusion Criteria:

* Participants with stroke or brain injury
* Cognitive deficits

Exclusion Criteria:

* Uncontrolled medical comorbidities
* Not able to perform outcome measurements
* Aphasia, which hamper communication
* Pre-diagnosed psychological or other neurological disease not relevant to stroke or brain injury

Primary outcomes:
measure: Change from baseline Cambridge Neuropsychological Test Automated Battery(CANTAB) Spatial working memory at 34 th intervention
timeFrame: Baseline, 34th day from baseline
measure: Change from baseline CANTAB Rapid Visual information Processing at 34 th intervention
timeFrame: Baseline, 34th day from baseline
Secondary outcomes:
measure: CANTAB Spatial working memory
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Rapid Visual information Processing
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Motor control task
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Paired Associated Learning
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB reaction time
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Attention Switching Task
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Stoking of Cambridge
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Emotion Recognition Task
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: CANTAB Stop Signal Task
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: Geriatric depression scale
timeFrame: Baseline, 34th day from baseline
measure: Beck depression index
timeFrame: Baseline, 34th day from baseline
measure: Korean Mini-Mental State Examination (K-MMSE)
timeFrame: Baseline, 34th day from baseline
measure: Korean activities of daily living (K-ADL)
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: Korean instrumental activities of daily living (K-IADL)
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: clinical dementia rating scale (CDR)
timeFrame: Baseline, 34th day from baseline
measure: Stroke impact scale
timeFrame: Baseline, 34th day from baseline
measure: Subjective memory complaint questionnaire
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: NIH toolbox
timeFrame: Baseline, 17th day from baseline, 34th day from baseline, 64th day from baseline
measure: Autobiographical memory
timeFrame: Baseline, 34th day from baseline
measure: Trail making test (A/B)
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
measure: Trail making test - Black and White
timeFrame: Baseline, 34th day from baseline, 64th day from baseline
Other outcomes:
Locations:
city: Seoul
country: Korea, Republic of
facility: National Rehabilitation Center
Study officials:
References:
citation: Gibson E, Koh CL, Eames S, Bennett S, Scott AM, Hoffmann TC. Occupational therapy for cognitive impairment in stroke patients. Cochrane Database Syst Rev. 2022 Mar 29;3(3):CD006430. doi: 10.1002/14651858.CD006430.pub3.