Clinical trial NCT04913857: Effects of SUDOKU Mind Activation & Revitalizing Training on Cognitive Function in People With Mild Cognitive Impairment
Official title: New Wine in Old Bottle: the Effects of SUDOKU Mind Activation and Revitalizing Training (SMART) Program on Cognitive Function Among People With Mild Cognitive Impairment
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Mild Cognitive Impairment
Keywords: Mild Cognitive Impairment
Lead sponsor: The University of Hong Kong
Sponsor class: OTHER
First posted: 2021-06-04
Enrollment: 262
Sex: ALL
Minimum age (years): 55
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: To implement a SMART Program to promote cognitive health among patients with MCI, and the use of active mind strategy in preventing dementia among the older adults
Primary purpose: SUPPORTIVE_CARE

Brief summary: This study aims to implement a SUDOKU Mind Activation and Revitalization Training (SMART) Program to promote cognitive health among patients with mild cognitive impairment (MCI), and the use of active mind strategy in preventing dementia among the older adults. The SMART Program consists of two components including, a community empowerment-educational campaign on active mind strategies for older adults, and a 24-week SUDOKU Training Programme for people with MCI.

Detailed description: This study aims to implement a SMART Program to promote cognitive health among patients with MCI, and the use of active mind strategy in preventing dementia among the older adults. The SMART Program consists of two components including, a community empowerment-educational campaign on active mind strategies for older adults, and a 24-week SUDOKU Training Programme for people with MCI.

The community empowerment-educational campaign will be conducted in the elderly care centres of the two collaborating non-governmental organizations, with the purpose of increasing the awareness of people aged 55 or above on the importance of maintaining an active mind and preventing age-related cognitive decline and dementia. The campaign will include cognitive screening, poster exhibition, booth exhibition and individual counselling.

The SUDOKU training program include a 12-week face-to-face training session and a 12-week facilitated self-practice. The face-to-face sessions aim at developing the skills of the participants in solving the SUDOKU using the T-code. The 12-week training program will be evenly divided into three modules of increasing difficulty, with consideration given to the suboptimal cognitive function of the participants with MCI. These modules are developed by the Co-investigator who has rich prior experience in teaching older adults on SUDOKU puzzle.

Eligibility criteria: Inclusion Criteria:

* People with MCI as defined by a score of 19-26 out of the 30 on the Montreal Cognitive Assessment in the general public and aged 55 or above.

Exclusion Criteria:

* Persons with dementia and communication problems will be excluded.

Primary outcomes:
measure: Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)
timeFrame: Baseline
measure: Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)
timeFrame: 12-week
measure: Cantonese version of the Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-Cog)
timeFrame: 24-week
measure: The digit span-forward and backward test
timeFrame: Baseline
measure: The digit span-forward and backward test
timeFrame: 12-week
measure: The digit span-forward and backward test
timeFrame: 24-week
measure: The list learning delayed recall test
timeFrame: Baseline
measure: The list learning delayed recall test
timeFrame: 12-week
measure: The list learning delayed recall test
timeFrame: 24-week
measure: Trail-Making Test Part A and B
timeFrame: Baseline
measure: Trail-Making Test Part A and B
timeFrame: 12-week
measure: Trail-Making Test Part A and B
timeFrame: 24-week
Secondary outcomes:
measure: Memory Inventory for Chinese
timeFrame: Baseline
measure: Memory Inventory for Chinese
timeFrame: 12-week
measure: Memory Inventory for Chinese
timeFrame: 24-week
measure: The 36-item Chinese version of the Short Form 36 (SF-36)
timeFrame: Baseline
measure: The 36-item Chinese version of the Short Form 36 (SF-36)
timeFrame: 24-week
Other outcomes:
measure: 13-item satisfaction survey - for SMART Program
timeFrame: 12-week
measure: 10-item satisfaction survey - for community empowerment-educational campaign
timeFrame: 10-month
Locations:
city: Hong Kong
country: Hong Kong
facility: Department of Medicine and Geriatrics, United Christian Hospital
Study officials:
affiliation: The University of Hong Kong
name: Doris, Sau Fung YU, PhD
role: PRINCIPAL_INVESTIGATOR
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