Clinical trial NCT02054962: Persistent Pain Among Elderly Experiencing Motor Vehicle Collision
Official title: Persistent Pain and Associated Functional Decline Among Elderly Experiencing Motor Vehicle Collision
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Persistent Pain After Injury
Functional Decline After Injury
Keywords: Pain
Lead sponsor: University of North Carolina, Chapel Hill
Sponsor class: OTHER
Collaborators: name: National Institute on Aging (NIA)
First posted: 2014-02-04
Enrollment: 211
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Elderly experiencing motor vehicle collision

Brief summary: Chronic problems after traumatic events are common in non-elderly adults. Previous studies have shown that after minor motor vehicle collision (MVC), 10-30% of non-elderly adult patients develop chronic regional pain (neck or back pain). In addition, up to 1/3 of non-elderly adults will develop psychological sequelae, including posttraumatic stress disorder, depression, and anxiety disorders. There have been no prospective studies examining the frequency or predictors of persistent pain or psychological sequelae in older adults. The proposed study seeks to determine the frequency of persistent pain, psychological sequelae, and associated disability in older adults after minor MVC trauma and to identify candidate predictors for a model of adverse outcomes after MVC in this population. 200 individuals over 65 years of age will be recruited from emergency departments in four states with no-fault accident laws. Patients who meet inclusion criteria and who consent to the emergency department (ED) study will undergo a 30-45 minute ED assessment of crash-related, psychosocial, and biological factors, and complete telephone follow-ups at 2 weeks, 6 weeks 6 months, and 12 months. The wealth of information gained from this study will be used to determine the frequency of adverse events in older adults after MVC and to identify high risk elderly patients. These results will inform subsequent development of secondary pharmacologic and/or behavioral interventions to prevent chronic pain and psychological sequelae after traumatic events in older adults.


Eligibility criteria: Inclusion Criteria:

* Patient speaks English, presented to ER less than 24 hours after an MVC, patient has an address and telephone

Exclusion Criteria:

* Patient
* is a prisoner,
* has fractures or an intracranial injury,
* has injuries that are life threatening or expected to result in hospitalization for more than 72 hours,
* is receiving end of life, hospice, or comfort care, or
* is considered ineligible by treating physician.

Primary outcomes:
measure: Average pain 6 months after Emergency Department visit
timeFrame: 6 months
Secondary outcomes:
measure: Physical function at 6 months after Emergency Department visit
timeFrame: 6 months
Other outcomes:
Locations:
city: Grand Rapids
country: United States
facility: Spectrum Health - Butterworth Hospital
state: Michigan
Study officials:
affiliation: UNC Chapel Hill
name: Timothy F Platts-Mills, MD, MSc
role: STUDY_DIRECTOR
References: