Clinical trial NCT04244643: Ocular Surface in Patients With Soft Contact Lenses
Official title: Ocular Surface in Patients With Soft Contact Lenses
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Ocular Surface
Keywords: contact lenses
Lead sponsor: Centre Hospitalier Universitaire de Saint Etienne
Sponsor class: OTHER
Collaborators: name: Société Française des Ophtalmologistes Adaptateurs de Lentilles de Contact
First posted: 2020-01-28
Enrollment: 524
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with soft contact lenses

Brief summary: Contact lenses modify the structure of the tear film by biophysical and biochemical interactions. These changes may explain more common dry eye symptoms and may sometimes cause lens failure or discontinuation.

In recent years, the investigators have various objective non-invasive methods of tear film evaluation such as the non-invasive break up time, interferometry, and tears meniscus height. These measurements are performed in clinical practice during consultation by devices such as LACRYDIAG.

The improvement of lens comfort requires a better knowledge of the ocular surface in patients with contact lenses. But currently none of these objective parameters have been accurately described.

Therefore, the investigators would like to build a database to describe the different parameters of ocular surface in patients with soft contact lenses.


Eligibility criteria: Inclusion Criteria:

* Patients with soft contact lenses
* Patients with their contact lenses on the eyes at the time of the examination and having undergone a LACRYDIAG examination
* Only Right eye analyze

Exclusion Criteria:

* Patients with rigid contact lenses
* Patients not wearing their lenses at the time of the examination

Primary outcomes:
measure: eye surface condition
timeFrame: baseline
Secondary outcomes:
measure: refraction
timeFrame: baseline
measure: Ocular Surface Disease Index score
timeFrame: baseline
measure: non-invasive tear break-up time
timeFrame: baseline
measure: interferometry
timeFrame: baseline
measure: tears meniscus height
timeFrame: baseline
Other outcomes:
Locations:
city: Beausoleil
country: France
facility: Cabinet médico-chirurgical de l'Alcazar
city: Blagnac
country: France
facility: Cabinet du Dr Virginie MADARIAGA
city: Bordeaux
country: France
facility: Point Vision Bordeaux
city: Draguignan
country: France
facility: Cabinet du Dr Françoise LE CHERPIE
city: Lille
country: France
facility: Cabinet du Dr Hélène Bertrand
city: Paris
country: France
facility: Centre ophtalmologique Saint-Paul
city: Paris
country: France
facility: Point Vision Paris Royale
city: Paris
country: France
facility: Centre hospitalier national d'ophtalmologie des Quinze-Vingts
city: Paris
country: France
facility: Cabinet du Dr Cyrille TEMSTET
city: Saint Etienne
country: France
facility: CHU de Saint Etienne
city: Saint-Laurent-du-Var
country: France
facility: Point Vision Nice - St Laurent du Var
city: Toulouse
country: France
facility: Clinique St Jean Languedoc
Study officials:
affiliation: CHU de Saint Etienne
name: Marie Caroline TRONE
role: PRINCIPAL_INVESTIGATOR
References: