Clinical trial NCT06945991: Application and Effect Evaluation of Integrated Nursing and Medical Management in Pediatric Lobar Pneumonia
Official title: Application and Effect Evaluation of Integrated Nursing and Medical Management in Pediatric Lobar Pneumonia
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Pediatrics
Lobar Pneumonia
Inflammatory Markers
Satisfaction
Lead sponsor: Children's Hospital of Hebei Province
Sponsor class: OTHER
First posted: 2025-04-27
Enrollment: 50
Sex: ALL
Minimum age (years): 1
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Fifty pediatric patients diagnosed with lobar pneumonia and admitted to our hospital between January and December 2023 were selected and randomly assigned to either the observation group or the control group (n = 25 each) using a random number table.

Brief summary: Integrated nursing and medical management significantly improves clinical symptoms and pulmonary function in children with lobar pneumonia, shortens hospitalization duration, reduces complication rates, and enhances caregiver satisfaction. These findings support its broad clinical applicability and value.

Detailed description: This study aims to evaluate the clinical efficacy of integrated nursing and medical management in the treatment of pediatric lobar pneumonia. Specifically, it assesses its impact on symptom relief, pulmonary function recovery, inflammatory response control, duration of hospitalization, and caregiver satisfaction. Fifty pediatric patients diagnosed with lobar pneumonia and admitted to our hospital between January and December 2023 were selected and randomly assigned to either the observation group or the control group (n = 25 each) using a random number table. The control group received routine nursing care, while the observation group was additionally managed with an integrated nursing and medical approach. The two groups were compared in terms of duration of fever, cough, pulmonary rales, antibiotic treatment, length of hospital stay, pulmonary function parameters (FEV₁, FVC, FEV₁/FVC), inflammatory markers (CRP, WBC, PCT, LDH), overall treatment efficacy, caregiver satisfaction, and incidence of adverse events.

Eligibility criteria: Inclusion Criteria:

* (1) Met the diagnostic criteria for lobar pneumonia, presenting with symptoms such as fever, cough, and pulmonary rales, and confirmed by laboratory tests and chest X-ray;
* (2) Aged between 1 and 12 years;
* (3) Informed consent was obtained from the child's legal guardians.

Exclusion Criteria:

* (1)Presence of other concurrent respiratory diseases;
* (2) Congenital or acquired airway malformations, or airway foreign bodies;
* (3) Impaired hepatic or renal function;
* (4) Presence of other systemic diseases;
* (5) Cognitive impairment.

Primary outcomes:
measure: Time to Clinical Resolution of Symptoms
timeFrame: From admission until discharge (up to 14 days).
Secondary outcomes:
measure: Change in Pulmonary Function (FEV₁, FVC, FEV₁/FVC)
timeFrame: Baseline (T0) and discharge (T1; up to 14 days).
measure: Reduction in Inflammatory Markers (CRP, PCT, WBC, LDH)
timeFrame: Baseline (T0) and discharge (T1; up to 14 days).
measure: Length of Hospital Stay
timeFrame: Up to 14 days.
measure: Parental Satisfaction Rate
timeFrame: At discharge (T1; up to 14 days).
Other outcomes:
measure: Incidence of Complications
timeFrame: From admission to discharge (up to 14 days).
measure: Antibiotic Usage Duration
timeFrame: From admission to discontinuation (up to 14 days).
measure: Adherence to Rehabilitation Protocols
timeFrame: Daily during hospitalization (up to 14 days).
Locations:
city: Shijiazhuang
country: China
facility: Hebei Children's Hospital
Study officials:
References: