Clinical trial NCT01302067: A 12 Week Study to Confirm the Effectiveness of 8mg of Fesoterodine Compared to 4mg of Fesoterodine
Official title: A 12-Week, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multicenter Trial In Overactive Bladder Subjects To Confirm The Efficacy Of 8 Mg Fesoterodine Compared To 4 Mg Fesoterodine.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE4
Conditions: Overactive Bladder
Lead sponsor: Pfizer
Sponsor class: INDUSTRY
First posted: 2011-02-23
Enrollment: 2012
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: This study is designed to confirm if 8mg of fesoterodine is more effective in reducing overactive bladder symptoms than 4mg of fesoterodine. In addition the study is designed to assess if the higher dose reduces the overall effect of overactive bladder on the subject's daily life more than the lower dose. The study also assesses the side effects and safety of the two doses.


Eligibility criteria: Inclusion Criteria:

* 6 months overactive bladder symptoms, minimum of 2 urgency urinary incontinence episodes per 24 hours and minimum of 8 micturitions per 24 hours.

Exclusion Criteria:

* Other concurrent and concomitant medication or disease that could put the subjects at additional risk or interfere with the study results.

Primary outcomes:
measure: Change From Baseline in Mean Number of Urgency Urinary Incontinence (UUI) Episodes Per 24 Hours at Week 12.
timeFrame: Week 12
Secondary outcomes:
measure: Change From Baseline in Mean Number of Micturitions Per 24 Hours at Week 4.
timeFrame: Week 4
measure: Change From Baseline in Mean Number of Micturitions Per 24 Hours at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Percentage of Micturitions Per 24 Hours at Week 4.
timeFrame: Week 4
measure: Change From Baseline in Percentage of Micturitions Per 24 Hours at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Mean Number of UUI Episodes Per 24 Hours at Week 4.
timeFrame: Week 4
measure: Change From Baseline in Percentage of UUI Episodes Per 24 Hours at Week 4.
timeFrame: Week 4
measure: Change From Baseline in Percentage of UUI Episodes Per 24 Hours at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Mean Number of Micturition-Related Urgency Episodes Per 24 Hours at Week 4.
timeFrame: Week 4
measure: Change From Baseline in Mean Number of Micturition-Related Urgency Episodes Per 24 Hours at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Percentage of Micturition-Related Urgency Episodes Per 24 Hours at Week 4.
timeFrame: Week 4
measure: Change From Baseline in Percentage of Micturition-Related Urgency Episodes Per 24 Hours at Week 12.
timeFrame: Week 12
measure: Number of Participants With Change From Baseline in Patient Perception of Bladder Condition (PPBC) at Week 12.
timeFrame: Week 12
measure: Number of Participants With Change From Baseline in Urgency Perception Scale (UPS) at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Overactive Bladder Questionnaire (OAB-q) Symptom Bother Score at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Health Related Quality of Life (HRQL)-Coping Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Health Related Quality of Life (HRQL)-Concern Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Health Related Quality of Life (HRQL)-Sleep Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Health Related Quality of Life (HRQL)-Social Interaction Domain and Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12.
timeFrame: Week 12
measure: Change From Baseline in Health Related Quality of Life (HRQL)-Total Score of Overactive Bladder Questionnaire (OAB-q) at Week 12.
timeFrame: Week 12
measure: Percentage of Participants Who Became Dry at Week 4.
timeFrame: Week 4
measure: Percentage of Participants Who Became Dry at Week 12.
timeFrame: Week 12
Other outcomes:
Locations:
city: Birmingham
country: United States
facility: Urology Centers of Alabama
state: Alabama
city: Birmingham
country: United States
facility: Achieve Clinical Research, LLC
state: Alabama
city: Huntsville
country: United States
facility: James Gordon McMurray, MD
state: Alabama
city: Huntsville
country: United States
facility: Medical Affiliated Research Center, Inc.
state: Alabama
city: Mobile
country: United States
facility: Mobile Ob-Gyn, P.C.
state: Alabama
city: Montgomery
country: United States
facility: Montgomery Women's Health Associates, P.C.
state: Alabama
city: Scottsboro
country: United States
facility: Scottsboro Quick Care Clinic
state: Alabama
city: Phoenix
country: United States
facility: Dedicated Clinical Research
state: Arizona
city: Tucson
country: United States
facility: Genova Clinical Research
state: Arizona
city: Jonesboro
country: United States
facility: NEA Baptist Women's Clinic
state: Arkansas
city: Little Rock
country: United States
facility: A Clinic For Women
state: Arkansas
city: Little Rock
country: United States
facility: Larry S. Watkins, MD
state: Arkansas
city: Little Rock
country: United States
facility: Lynn Institute of the Ozarks
state: Arkansas
city: Little Rock
country: United States
facility: May Women's Health Clinic
state: Arkansas
city: Carmichael
country: United States
facility: The Office of Dr. Simon Yassear, MD
state: California
city: Glendora
country: United States
facility: Citrus Valley Medical Research, Inc.
state: California
city: La Mesa
country: United States
facility: Grossmont Center for Clinical Research
state: California
city: Sacramento
country: United States
facility: Sockolov and Sockolov APC
state: California
city: San Diego
country: United States
facility: Genesis Center for Clinical Research
state: California
city: San Diego
country: United States
facility: San Diego Clinical Trials
state: California
city: Santa Ana
country: United States
facility: Clinical Innovations, Inc.
state: California
city: Walnut Creek
country: United States
facility: Diablo Clinical Research, Inc.
state: California
city: Denver
country: United States
facility: Urology Associates, PC
state: Colorado
city: Denver
country: United States
facility: Genitourinary Surgical Consultants
state: Colorado
city: Fort Collins
country: United States
facility: The Women's Clinic of Northern Colorado
state: Colorado
city: Farmington
country: United States
facility: Women's Health Specialty Care
state: Connecticut
city: Aventura
country: United States
facility: South Florida Medical Research
state: Florida
city: Aventura
country: United States
facility: Uromedix
state: Florida
city: Bradenton
country: United States
facility: Meridien Research
state: Florida
city: Brandon
country: United States
facility: Florida Sleep Disorder Center of Brandon
state: Florida
city: Brandon
country: United States
facility: PAB Clinical Research
state: Florida
city: Brandon
country: United States
facility: Pulmonary Associates of Brandon
state: Florida
city: Brooksville
country: United States
facility: Meridien Research
state: Florida
city: Crystal River
country: United States
facility: Nature Coast Clinical Research
state: Florida
city: DeFuniak Springs
country: United States
facility: Doctors Medical Center of Walton County
state: Florida
city: DeLand
country: United States
facility: Avail Clinical Research, LLC
state: Florida
city: Destin
country: United States
facility: SJS Clinical Research, Inc.
state: Florida
city: Fleming Island
country: United States
facility: Fleming Island Center for Clinical Research
state: Florida
city: Fort Lauderdale
country: United States
facility: M & O Clinical Research, LLC
state: Florida
city: Fort Myers
country: United States
facility: Florida Urology Physicians
state: Florida
city: Hialeah
country: United States
facility: Urological Research Network, LLC
state: Florida
city: Inverness
country: United States
facility: Nature Coast Clinical Research
state: Florida
city: Jacksonville
country: United States
facility: Jacksonville Center for Clinical Research
state: Florida
city: Lake Worth
country: United States
facility: Altus Research
state: Florida
city: Leesburg
country: United States
facility: OB-GYN Associates of Mid-Florida, PA
state: Florida
city: Miami
country: United States
facility: New Horizon Research Center
state: Florida
city: Ocala
country: United States
facility: Urology Health Team, PLLC
state: Florida
city: Pembroke Pines
country: United States
facility: Broward Research Group
state: Florida
city: Plant City
country: United States
facility: Clinical Research of Central Florida
state: Florida
city: Tallahassee
country: United States
facility: Southeastern Research Group, Inc.
state: Florida
city: Tampa
country: United States
facility: Meridien Research
state: Florida
city: West Palm Beach
country: United States
facility: Advanced OBGYN Associates
state: Florida
city: Winter Haven
country: United States
facility: Clinical Research of Central Florida
state: Florida
city: Roswell
country: United States
facility: North Fulton Urology, PC
state: Georgia
city: Stockbridge
country: United States
facility: Clinical Research Atlanta
state: Georgia
city: Woodstock
country: United States
facility: North Georgia Clinical Research
state: Georgia
city: Woodstock
country: United States
facility: North Georgia Internal Medicine
state: Georgia
city: Idaho Falls
country: United States
facility: Women's Healthcare Associates dba Rosemark WomenCare Specialists
state: Idaho
city: Meridian
country: United States
facility: Advanced Clinical Research
state: Idaho
city: Champaign
country: United States
facility: Women's Health Practice
state: Illinois
city: Chicago
country: United States
facility: Center for Women's Research
state: Illinois
city: Galesburg
country: United States
facility: Medical and Surgical Specialists
state: Illinois
city: Gurnee
country: United States
facility: Clinical Investigation Specialists, Inc.
state: Illinois
city: Avon
country: United States
facility: American Health Network of Indiana, LLC
state: Indiana
city: Bloomington
country: United States
facility: Summit Research Institute
state: Indiana
city: Evansville
country: United States
facility: MediSphere Medical Research Center, LLC
state: Indiana
city: Greenfield
country: United States
facility: American Health Network of Indiana, LLC
state: Indiana
city: Jeffersonville
country: United States
facility: Metropolitan Urology
state: Indiana
city: Newburgh
country: United States
facility: Deaconess Clinic Gateway Health Center
state: Indiana
city: Iowa City
country: United States
facility: University of Iowa Healthcare
state: Iowa
city: Pratt
country: United States
facility: Health Science Research Center
state: Kansas
city: Shawnee
country: United States
facility: Women's and Family Care dba GTC Research
state: Kansas
city: Wichita
country: United States
facility: Heartland Research Associates, LLC
state: Kansas
city: Lexington
country: United States
facility: Kentucky Medical Research Center
state: Kentucky
city: Madisonville
country: United States
facility: Commonwealth Biomedical Research
state: Kentucky
city: Mount Sterling
country: United States
facility: Central Kentucky Research Associates, Inc.
state: Kentucky
city: Mount Sterling
country: United States
facility: Mount Sterling Clinic
state: Kentucky
city: Greenbelt
country: United States
facility: The Office of Dr. Myron I. Murdock, MD, LLC
state: Maryland
city: Boston
country: United States
facility: Boston Clinical Trials, Inc.
state: Massachusetts
city: Brockton
country: United States
facility: Beacon Clinical Research, LLC
state: Massachusetts
city: Hyannis
country: United States
facility: Clinical Research Center of Cape Cod, Inc.
state: Massachusetts
city: North Dartmouth
country: United States
facility: Infinity Medical Research
state: Massachusetts
city: Springfield
country: United States
facility: DM Clinical Research
state: Massachusetts
city: Chesterfield
country: United States
facility: Clinical Research Institute of Michigan, LLC
state: Michigan
city: Jackson
country: United States
facility: CRC of Jackson
state: Mississippi
city: Jackson
country: United States
facility: Mississippi Urology Clinic
state: Mississippi
city: St. Louis
country: United States
facility: Mercy Health Research
state: Missouri
city: St. Peters
country: United States
facility: Midwest Pharmaceutical Research
state: Missouri
city: Lincoln
country: United States
facility: Family Health Care Center
state: Nebraska
city: Lincoln
country: United States
facility: Women's Clinic of Lincoln, P.C.
state: Nebraska
city: Lincoln
country: United States
facility: Lincoln Internal Medicine Associates
state: Nebraska
city: Las Vegas
country: United States
facility: Clinical Research Center of Nevada
state: Nevada
city: Las Vegas
country: United States
facility: Clinical Research Center of Nevada
state: Nevada
city: Moorestown
country: United States
facility: Virtua Phoenix Ob-Gyn
state: New Jersey
city: Trenton
country: United States
facility: Premier Research, Inc.
state: New Jersey
city: Binghamton
country: United States
facility: United Medical Associates
state: New York
city: Brooklyn
country: United States
facility: Brooklyn Urology Research Group
state: New York
city: Garden City
country: United States
facility: Urological Surgeons of Long Island
state: New York
city: Kingston
country: United States
facility: Premier Medical Group of the Hudson Valley
state: New York
city: New Windsor
country: United States
facility: Mid Hudson Medical Research, PLLC
state: New York
city: Poughkeepsie
country: United States
facility: Premier Medical Group of the Hudson Valley
state: New York
city: Williamsville
country: United States
facility: Upstate Clinical Research Associates
state: New York
city: Burlington
country: United States
facility: Kernodle Clinic, Inc.
state: North Carolina
city: Charlotte
country: United States
facility: American Health Research
state: North Carolina
city: Concord
country: United States
facility: Carolina Clinical Trials
state: North Carolina
city: Concord
country: United States
facility: Carolina Urology Partners, PLLC
state: North Carolina
city: Harrisburg
country: United States
facility: Carolinas Research Associates
state: North Carolina
city: Huntersville
country: United States
facility: University Medical Associates
state: North Carolina
city: Raleigh
country: United States
facility: Wake Internal Medicine Consultants, Inc.
state: North Carolina
city: Raleigh
country: United States
facility: Wake Research Associates, LLC
state: North Carolina
city: Wilmington
country: United States
facility: PMG Research of Wilmington, LLC
state: North Carolina
city: Winston-Salem
country: United States
facility: Hawthorne Medical Research, Inc. - Hawthorne OB/GYN Associates
state: North Carolina
city: Winston-Salem
country: United States
facility: Hawthorne Medical Research, Inc.
state: North Carolina
city: Cincinnati
country: United States
facility: Patient Priority Clinical Sites, LLC
state: Ohio
city: Cleveland
country: United States
facility: Rapid Medical Research, Inc.
state: Ohio
city: Columbus
country: United States
facility: Columbus Center for Women's Health Research
state: Ohio
city: Columbus
country: United States
facility: Columbus Clinical Research
state: Ohio
city: Dayton
country: United States
facility: Hometown Urgent Care and Research
state: Ohio
city: Englewood
country: United States
facility: HWC Women's Research Center
state: Ohio
city: Willoughby Hills
country: United States
facility: Ohio Clinical Research, LLC
state: Ohio
city: Edmond
country: United States
facility: The Office of Johnny B. Roy, MD
state: Oklahoma
city: Oklahoma City
country: United States
facility: Legacy Clinical Research, LLC
state: Oklahoma
city: Oklahoma City
country: United States
facility: Lynn Health Science Institute
state: Oklahoma
city: Allentown
country: United States
facility: Institute for Female Pelvic Medicine
state: Pennsylvania
city: Hopwood
country: United States
facility: Laurel Highlands OB/GYN
state: Pennsylvania
city: Jenkintown
country: United States
facility: The Clinical Trial Center, LLC
state: Pennsylvania
city: Johnstown
country: United States
facility: Richard Kastelic and Associates
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Clinical Trials Research Services, LLC
state: Pennsylvania
city: Pittsburgh
country: United States
facility: Triangle Urological Group
state: Pennsylvania
city: State College
country: United States
facility: Mount Nittany Medical Center Health Services Inc. dba Mount Nittany Physician Group
state: Pennsylvania
city: Uniontown
country: United States
facility: Pish Medical Associates
state: Pennsylvania
city: West Reading
country: United States
facility: Advanced Clinical Concepts
state: Pennsylvania
city: West Reading
country: United States
facility: Woman's Clinic Ltd.
state: Pennsylvania
city: East Greenwich
country: United States
facility: Coastal Medical
state: Rhode Island
city: East Providence
country: United States
facility: Safe Harbor Clinical Research
state: Rhode Island
city: Warwick
country: United States
facility: Omega Medical Research
state: Rhode Island
city: Columbia
country: United States
facility: TLM Medical Services, LLC
state: South Carolina
city: Mt. Pleasant
country: United States
facility: Coastal Carolina Research Center
state: South Carolina
city: West Columbia
country: United States
facility: Southern Urogynecology
state: South Carolina
city: Bristol
country: United States
facility: Internal Medicine and Pediatric Associates of Bristol, PC
state: Tennessee
city: Bristol
country: United States
facility: PMG Research of Bristol, LLC
state: Tennessee
city: Memphis
country: United States
facility: Adams Patterson Gynocology and Obstetrics, PLLC
state: Tennessee
city: New Tazewell
country: United States
facility: Heartland Medical PC
state: Tennessee
city: Austin
country: United States
facility: Austin Center for Clinical Research
state: Texas
city: Dallas
country: United States
facility: RJE Clinical Research
state: Texas
city: Houston
country: United States
facility: Memorial Clinical Associates dba MCA Research
state: Texas
city: Plano
country: United States
facility: ACRC Trials (Administrative/Mailing Site)
state: Texas
city: Plano
country: United States
facility: North Texas Family Medicine
state: Texas
city: San Antonio
country: United States
facility: Clinical Trials of Texas, Inc.
state: Texas
city: San Antonio
country: United States
facility: Institute for Women's Health
state: Texas
city: San Antonio
country: United States
facility: Seven Oaks Women's Center
state: Texas
city: San Antonio
country: United States
facility: Clinical Trials of Texas, Inc.
state: Texas
city: Temple
country: United States
facility: Scott and White Healthcare
state: Texas
city: Temple
country: United States
facility: Scott and White Healthcare
state: Texas
city: Charlottesville
country: United States
facility: Charlottesville Medical Research
state: Virginia
city: Richmond
country: United States
facility: National Clinical Research - Richmond
state: Virginia
city: Virginia Beach
country: United States
facility: Independence Family Medicine
state: Virginia
city: Burien
country: United States
facility: Seattle Urology Research Center
state: Washington
city: Charleston
country: United States
facility: CAMC Clinical Trials Center
state: West Virginia
city: Charleston
country: United States
facility: CAMC Physicians Group
state: West Virginia
city: Charleston
country: United States
facility: Charleston Internal Medicine, Inc.
state: West Virginia
city: Charleston
country: United States
facility: Urologic Surgical Center
state: West Virginia
city: Kenosha
country: United States
facility: Clinical Investigation Specialists, Inc.
state: Wisconsin
city: Oregon
country: United States
facility: Dean Oregon Clinic
state: Wisconsin
city: Wauwatosa
country: United States
facility: Allegiance Research Specialists
state: Wisconsin
city: Buenos Aires
country: Argentina
facility: Instituto Urologico Buenos Aires
city: Buenos Aires
country: Argentina
facility: Centro de Urología (CDU)
city: Buenos Aires
country: Argentina
facility: Instituto Medico Especializado (IME)
city: Victoria
country: Canada
facility: Office of Dr. Peter Pommerville
state: British Columbia
city: Victoria
country: Canada
facility: Can-Med Clinical Research
state: British Columbia
city: Victoria
country: Canada
facility: Office of Dr. Nazmuddin Merali
state: British Columbia
city: Victoria
country: Canada
facility: Can-Med Clinical Research Incorporated
state: British Columbia
city: Grand Falls-Windsor
country: Canada
facility: Pharos Medical Research Ltd.
state: Newfoundland and Labrador
city: Halifax
country: Canada
facility: Queen Elizabeth Health Sciences Centre
state: Nova Scotia
city: Hamilton
country: Canada
facility: McMaster Institute of Urology, St Joseph's Healthcare Hamilton
state: Ontario
city: North Bay
country: Canada
facility: Office of Dr. Bernard Goldfarb
state: Ontario
city: North York
country: Canada
facility: Stanley Flax Medical Professional Corporation
state: Ontario
city: Oshawa
country: Canada
facility: Urotec
state: Ontario
city: Toronto
country: Canada
facility: Toronto Western Hospital, University Health Network
state: Ontario
city: Toronto
country: Canada
facility: Toronto Urology Clinical Study Group
state: Ontario
city: Greenfield Park
country: Canada
facility: Urology South Shore Research
state: Quebec
city: Laval
country: Canada
facility: UroLaval
state: Quebec
city: Pointe-Claire
country: Canada
facility: Ultra-Med Inc.
state: Quebec
city: Sherbrooke
country: Canada
facility: Centre Hospitalier Universitaire de Sherbrooke
state: Quebec
city: Santiago
country: Chile
facility: Clinica Uromed
state: RM
city: Santiago
country: Chile
facility: Hospital Clinico Universidad de Chile
state: RM
city: Medellin
country: Colombia
facility: Fundacion Centro de Investigacion Clinica CIC
state: Antioquia
city: Bogota
country: Colombia
facility: Solano Y Terront Servicios Medicos Ltda / Unidad Integral de Endocrinologia Uniendo
state: Cundinamarca
city: Benesov
country: Czech Republic
facility: Urologicka ambulance
city: Hradec Kralove
country: Czech Republic
facility: FN a LFUK Hradec Kralove/Urologicka klinika
city: Jablonec nad Nisou
country: Czech Republic
facility: Nemocnice Jablonec nad Nisou
city: Praha 1 - Nove Mesto
country: Czech Republic
facility: Urologicka klinika
city: Praha 5
country: Czech Republic
facility: Fakultni nemocnice v Motole
city: Praha 6 - Hradcany
country: Czech Republic
facility: Androgeos spol. s.r.o.
city: Znojmo
country: Czech Republic
facility: Urologicka ambulance
city: Herlev
country: Denmark
facility: Herlev Hospital
city: Roskilde
country: Denmark
facility: Roskilde sygehus, Gynaekologisk/obstetrisk afdeling
city: Cairo
country: Egypt
facility: Al-Azhar University hospital
city: Kouvola
country: Finland
facility: Kouvolan Lääkäriasema
city: Kuopio
country: Finland
facility: Lääkäriasema Cantti Oy
city: Lyon Cedex 03
country: France
facility: Hôpital Edouard Herriot
city: Nantes
country: France
facility: CHU de Nantes - Hôtel Dieu
city: Nimes Cedex 9
country: France
facility: Hôpital CAREMEAU - Service Urologie/Andrologie
city: Paris
country: France
facility: Hôpital Tenon - Service d'Urologie
city: Alzey
country: Germany
facility: Arztpraxis
city: Berlin
country: Germany
facility: Synexus Clinical Research GmbH
city: Berlin
country: Germany
facility: Klinische Forschung Berlin-Buch GmbH
city: Bochum
country: Germany
facility: Synexus Clinical Research GmbH
city: Dresden
country: Germany
facility: Klinische Forschung Dresden GmbH
city: Frankfurt am Main
country: Germany
facility: Synexus Clinical Research GmbH
city: Goerlitz
country: Germany
facility: Synexus Clinical Research GmbH
city: Hamburg
country: Germany
facility: Clinical Research Hamburg
city: Hannover
country: Germany
facility: Klinische Forschung Hannover - Mitte GmbH
city: Karlsruhe
country: Germany
facility: Allgemeinmedizin Praktische Aerzte
city: Lauenburg
country: Germany
facility: Arztpraxis
city: Leipzig
country: Germany
facility: Synexus Clinical Research GmbH
city: Magdeburg
country: Germany
facility: SMO MD GmbH
city: Moenchengladbach
country: Germany
facility: CRS Clinical Research Service Moenchengladbach GmbH
city: Muelheim a.d. Ruhr
country: Germany
facility: Praxisklinik Urologie Rhein-Ruhr
city: Reutlingen
country: Germany
facility: Facharzt fuer Urologie
city: Schwerin
country: Germany
facility: Klinische Forschung Schwerin GmbH
city: Larisa
country: Greece
facility: University General Hospital of Larisa/ Urology Department
city: Thessaloniki
country: Greece
facility: General Hospital Papageorgiou
city: Budapest
country: Hungary
facility: Synexus Magyarorszag Kft.
city: Budapest
country: Hungary
facility: Jahn Ferenc Del-pesti Korhaz, Urologiai Osztaly
city: Debrecen
country: Hungary
facility: Debreceni Egyetem Orvos- es Egeszsegtudomanyi Centrum, Urologiai Klinika
city: Nyiregyhaza
country: Hungary
facility: Josa Andras Oktatokorhaz Egeszsegugyi Szolgaltato Nonprofit Kft., Urologiai osztaly
city: Catanzaro
country: Italy
facility: Università Magna Graecia di Catanzaro
city: Foggia
country: Italy
facility: Clinica Urologica Centro Trapianti di rene
city: Seoul
country: Korea, Republic of
facility: Seoul National University Hospital
city: Seoul
country: Korea, Republic of
facility: Severance Hospital, Yonsei University College of Medicine, Department of Urology
city: Seoul
country: Korea, Republic of
facility: Samsung Medical Center
city: Seoul
country: Korea, Republic of
facility: Department of Urology, Korea University Anam Hospital
city: Seoul
country: Korea, Republic of
facility: The Catholic University of Korea Seoul St. Mary's Hospital, Department of Urology
city: Seoul
country: Korea, Republic of
facility: Asan Medical Center, Department of Urology
city: Kaunas
country: Lithuania
facility: Saules Seimos Medicinos Centras, JSC
city: Klaipeda
country: Lithuania
facility: Mano Seimos Gydytojas, JSC
city: Vilnius
country: Lithuania
facility: Seimos Gydytojas, JSC
city: San Luis Potosi
country: Mexico
facility: Hospital Lomas de San Luis Internacional
city: Elverum
country: Norway
facility: Medi 3 Elverum AS
city: Hamar
country: Norway
facility: Medi 3 Innlandet
city: Lierskogen
country: Norway
facility: Norsk Helseklinikk AS, c/o Heiaklinikken
city: Stavanger
country: Norway
facility: Forusakutten AS, Avdeling for oppdragsforskning
city: Cebu City
country: Philippines
facility: Perpetual Succour Hospital of Cebu Inc.
state: Cebu
city: Bacolod City
country: Philippines
facility: Dr. Pablo O. Torre Memorial Hospital
city: Iloilo City
country: Philippines
facility: St. Paul's Hospital
city: Gdansk
country: Poland
facility: Klinika Urologii Akademickie Centrum Kliniczne - Szpital Akademii Medycznej w Gdansku
city: Lodz
country: Poland
facility: NZOZ Centrum Medyczne
city: Myslowice
country: Poland
facility: Centrum Urologiczne Sp. z o. o.
city: Torun
country: Poland
facility: Nzoz "Nasz Lekarz"
city: Barnaul
country: Russian Federation
facility: Non-governmental Healthcare Institution Departmental Clinical Hospital at Barnaul station OAO RZD
city: Rostov-on-Don
country: Russian Federation
facility: Rostov State Medical University, Chair of Urology
city: Saint-Petersburg
country: Russian Federation
facility: Research Institute of Obstetrics and Gynaecology D.O. Otta of North-west Department of RAMS
city: Bratislava
country: Slovakia
facility: URO CLINIC, s.r.o.
city: Bratislava
country: Slovakia
facility: Ruzinovska poliklinika, a.s.
city: Galanta
country: Slovakia
facility: Nemocnica s Poliklinikou Svateho Lukasa Galanta
city: Piestany
country: Slovakia
facility: UROX s.r.o.
city: Povazska Bystrica
country: Slovakia
facility: Centrum urologie Povazska Bystrica, s.r.o. urologicka ambulancia
city: Trencin
country: Slovakia
facility: Fakultna nemocnica Trencin
city: Zilina
country: Slovakia
facility: UROGYN,s.r.o.
city: Zilina
country: Slovakia
facility: Fakultna nemocnica s poliklinikou Zilina
city: Zvolen
country: Slovakia
facility: GYNPOR SK, s.r.o. Urogynekologicka ambulancia
city: Pretoria
country: South Africa
facility: Clinical Research Unit
state: Gauteng
city: Vosloorus
country: South Africa
facility: Clinix Private Clinic
state: Gauteng
city: Roodepoort
country: South Africa
facility: Mayo Centre
city: Eslov
country: Sweden
facility: Carema Specialistvard Eslov
city: Goteborg
country: Sweden
facility: Hagakliniken
city: Goteborg
country: Sweden
facility: CTC, Sahlgrenska sjukhuset/SU
city: Lund
country: Sweden
facility: Probare
city: Malmo
country: Sweden
facility: Center for Lakemedelsstudier
city: Skene
country: Sweden
facility: Ladulaas kliniska studier
city: Skovde
country: Sweden
facility: Verksamhet Urologi
city: Stockholm
country: Sweden
facility: Kvinnokliniken Karolinska Universitetssjukhuset Huddinge
city: Vallingby
country: Sweden
facility: S3 Clinical Research Centers
city: Vastervik
country: Sweden
facility: Vasterviks sjukhus, Kvinnokliniken
city: Kaohsiung
country: Taiwan
facility: Chang Gung Medical Foundation. Kaohsiung Chang Gung Memorial Hospital
city: Taipei
country: Taiwan
facility: National Taiwan University Hospital, Department of Urology
city: Taipei
country: Taiwan
facility: Taipei Veterans General Hospital/Division of Urology
city: Chernivtsi
country: Ukraine
facility: RMI "Chernivtsi Regional Clinical Hosp.", Dep. of Urology, BSMU, Chair of Surgery and Urology
city: Donetsk
country: Ukraine
facility: City Hospital #4 of Donetsk, Woman Consultative Department
city: Donetsk
country: Ukraine
facility: Department of Urology of Donetsk National Medical University at Central City Clinical Hospital #1
city: Donetsk
country: Ukraine
facility: MTPI "Central City Clinical Hospital #1"/Donetsk National Medical University n.a. M. Gorkiy,
city: Uzhorod
country: Ukraine
facility: Uzhorod City Outpatient Clinic, Prophylaxis Department
city: Vinnitsa
country: Ukraine
facility: Vinnitsa Regional Clinical Dispensary of Endocrinology
city: Zaporizhzhia
country: Ukraine
facility: Urology Dept of Zaporizhzhia Medical Academy of Postgraduate Education
city: Fowey
country: United Kingdom
facility: Fowey River Practice
state: Cornwall
city: Plymouth
country: United Kingdom
facility: Knowle House Surgery
state: Devon
city: Belfast
country: United Kingdom
facility: Ormeau Health Centre
state: Northern Ireland
city: Cambridge
country: United Kingdom
facility: Cambridge University Hospital Trials NHS Trust
city: Glasgow
country: United Kingdom
facility: Southern General Hospital
city: Glasgow
country: United Kingdom
facility: Baillieston Health Centre
city: Hertfordshire
country: United Kingdom
facility: Sheepcot Medical Centre
city: Sheffield
country: United Kingdom
facility: Royal Hallamshire Hospital
Study officials:
affiliation: Pfizer
name: Pfizer CT.gov Call Center
role: STUDY_DIRECTOR
References:
citation: Wagg AS, Herschorn S, Carlsson M, Fernet M, Oelke M. A plain language summary of the likelihood of symptom relief for patients taking fesoterodine for overactive bladder. J Comp Eff Res. 2022 Sep;11(13):919-925. doi: 10.2217/cer-2022-0041. Epub 2022 Jul 26.
citation: Chapple C, Schneider T, Haab F, Sun F, Whelan L, Scholfield D, Dragon E, Mangan E. Superiority of fesoterodine 8 mg vs 4 mg in reducing urgency urinary incontinence episodes in patients with overactive bladder: results of the randomised, double-blind, placebo-controlled EIGHT trial. BJU Int. 2014 Sep;114(3):418-26. doi: 10.1111/bju.12678. Epub 2014 Jul 1.