Clinical trial NCT05449626: Validity and Reliability of Turkish Version of Bayer Activities of Daily Living Scale
Official title: Validity and Reliability of Turkish Version of Bayer Activities of Daily Living Scale
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Alzheimer Disease
Activities of Daily Living
Keywords: Alzheimer's disease
Activities of Daily Living
Lead sponsor: Yeditepe University
Sponsor class: OTHER
First posted: 2022-07-08
Enrollment: 400
Sex: ALL
Minimum age (years): 60
Maximum age (years): 95
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: 200 individuals and healthy individuals who were diagnosed with Alzheimer's according to the international diagnostic criteria of the American National Neurological and Communication Disorders Stroke and Alzheimer Association (NINCDS-ADRDA) and were in mild and moderate stages (\<2) according to the Clinical Dementia Rating: CDR. 200 individuals found will be included

Brief summary: The aim of our study is to verify the validity and reliability of the Turkish version of B-GYA.

Detailed description: Dementia refers to a condition in which individuals with brain damage have multiple cognitive deficits with impairment in activities of daily living (ADL). Therefore, the assessment of ADL is one of the main criteria for evaluating dementia. ADL disorders are often observed by caregivers before they are identified by psychometric testing, thus suggesting that ADL assessment can contribute to the early detection of dementia.

Evaluation of ADL has become increasingly important with the introduction of new drugs for Alzheimer's disease (AD), as well as being a helpful tool in diagnosis. Current guidelines have recognized the need for therapeutic intervention in AD to measure and document treatment effects on ADL. It has been emphasized that internationally validated and approved test tools to evaluate dementia are important for multinational clinical drug trials that evaluate the efficacy of anti-dementia drugs. Therefore, it is of great importance to find ADL scales that can be used internationally. Various ADL scales have been developed, such as Lawton's instrumental ADL (IADL), functional activities questionnaire (FAQ), ADCS-ADL, and Bayer ADL (B-ADL). Of these, W-ADL was developed based on an international pilot study to evaluate ADL deficits in patients from different cultural backgrounds.

Specifically, through a collaborative study conducted in four different countries during the development of the RDA, the researchers prepared 141 items and selected 25 of them that could be used internationally. The target group of the scale included elderly patients suffering from mild to moderate dementia or cognitive impairment. European countries: In the United Kingdom, Germany, and Spain, the validation study of the B-ADL was carried out in three stages. The aim of our research is to verify the validity and reliability of the Turkish version of B-ADL.

Eligibility criteria: Inclusion Criteria:

* Individuals aged 60 and over
* Being literate
* Having given consent to participate in the study
* Individuals diagnosed with Alzheimer's according to the international diagnostic criteria of the American National Neurological and Communication Disorders Stroke and Alzheimer's Association (NINCDS-ADRDA) and in mild and moderate stages (\<2) according to the Clinical Dementia Rating: CDR will be included in the study.

Exclusion Criteria:

* Those who did not give consent to participate in the study
* CDR\>2
* Except for behavioral or functional symptoms associated with dementia, individuals with medical, psychiatric, neurological conditions, or physical disabilities that may significantly affect the performance of ADL will be excluded from the study.

Primary outcomes:
measure: Standardized Mini Mental Test
timeFrame: Up to 6 months
measure: Clinical Dementia Rating Scale
timeFrame: Up to 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Yeditepe University
state: Turkiye
Study officials:
References: