Clinical trial NCT06378762: Interference of Endurance Training on Strength Development and Neuromuscular Adaptations
Official title: Interference of Endurance Training on Strength Development and Neuromuscular Adaptations
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Exercise
Keywords: Neuromuscular adaptations
Concurrent training
Interference effect
Endurance
Strength
Lead sponsor: University of Lisbon
Sponsor class: OTHER
Collaborators: name: Fundação para a Ciência e a Tecnologia
First posted: 2024-04-22
Enrollment: 30
Sex: MALE
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: This study aims to find out if performing combined strength and endurance exercise in the same program (called concurrent training-CT) leads to similar long-term improvements in neuromuscular function as doing each type of exercise separately. The main questions it seeks to answer are:

Does performing CT result in similar improvements in strength and power as doing just strength training? Does performing CT result in similar improvements in cardiorespiratory fitness as doing just endurance training? Are neuromuscular adaptations similar between CT and just strength training? Researchers will compare the results between three groups: the CT group, the endurance training group (E), and the strength training group (S) to answer these questions.

Detailed description: This study looks at how different types of exercise affect neuromuscular and cardiorespiratory improvements over time. It aims to see how combining strength and endurance training (concurrent training - CT) affects neuromuscular and cardiorespiratory adaptations compared to doing just strength or endurance training. Participants who regularly do both types of exercise will be split into three groups: Concurrent training (CT), endurance training (E), or strength training (S) and will be involved in 11 weeks of supervised training, three days a week:

Endurance training involves 30 minutes of continuous running, three days a week, at an intensity corresponding to the heavy domain (between the first and second ventilatory threshold) Strength training includes weightlifting three days a week, focusing on building both strength and power.

Concurrent training incorporates both strength and endurance exercises in the same session, three days a week, with strength training being executed prior to endurance training.

Researchers will collect data at three time-points during the 11 weeks: before starting the program (Baseline), at the end of week 5 (Week 5), and at the end of the program (Week 11). Measurements include lower-body strength and power, aerobic capacity, nerve evoked responses, and muscle structure if the quadriceps femoris.

Researchers will then compare the CT, E, and S groups at each measurement point to see which type of training elicited the best adaptations for the different neuromuscular and cardiorespiratory outcomes.

Eligibility criteria: Inclusion Criteria:

* Active training status (strength and endurance (running) exercise at least 2 times per week over the last three months prior to inclusion in the study)

Exclusion Criteria:

* Active smoking status
* Orthopedic injuries
* On medication
* Known cardiovascular or respiratory disease

Primary outcomes:
measure: Maximal Isometric Strength
timeFrame: Baseline, Week 5, Week 11
measure: Maximal Dynamic Strength
timeFrame: Baseline, Week 5, Week 11
measure: Surface EMG
timeFrame: Baseline, Week 5, Week 11
measure: H-reflex excitability
timeFrame: Baseline, Week 5, Week 11
measure: V-wave
timeFrame: Baseline, Week 5, Week 11
measure: Lower Body Muscle Power
timeFrame: Baseline, Week 5, Week 11
measure: Muscle fascicle length
timeFrame: Baseline, Week 5, Week 11
measure: Muscle fascicle pennation angle
timeFrame: Baseline, Week 5, Week 11
measure: Muscle thickenss
timeFrame: Baseline, Week 5, Week 11
Secondary outcomes:
Other outcomes:
Locations:
city: Lisboa
country: Portugal
facility: Faculdade de Motricidade Humana - Universidade de Lisboa
state: Cruz Quebrada - Dafundo
Study officials:
References: