louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06286072: The Effect of Education and Reminder Messages on the Fatigue Level of Individuals With COPD
Official title: The Effect of Education and Reminder Messages on the Fatigue Level of Individuals With COPD: Randomised Controlled Study
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Copd
Fatigue
Keywords: COPD
Fatigue
dyspnea
Training
Message
Lead sponsor: Kirsehir Ahi Evran Universitesi
Sponsor class: OTHER
First posted: 2024-02-29
Enrollment: 120
Sex: ALL
Minimum age (years): 18
Maximum age (years): 85
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Randomised Controlled Trial
Primary purpose: SUPPORTIVE_CARE

Brief summary: COPD is an important respiratory system disease that progresses with damage to the airways.Increased mucus secretion and thickening in the airways causes obstruction.This obstruction causes symptoms such as shortness of breath, cough, phlegm and wheezing.The most obvious problem that the emerging symptoms will cause for the patient is fatigue.Coping with fatigue is an important problem in COPD.

The main questions it aims to answer are:

1. Does the training given in COPD affect the level of fatigue?
2. Do the education given and text messages sent regarding COPD affect the level of fatigue?

In this study, patients were given informative education about COPD and ways to cope with fatigue were explained. Then, in order to increase the permanence of the training, motivational messages and short briefings were continued for 8 weeks.2 messages were sent per week. Three groups were created to reveal the effectiveness of the trainings and messages.

Group 1 was trained and messages were sent for 8 weeks. Group 2 was trained and no message was sent. Group 3 is the control group. No training has been provided other than routine maintenance.

The initial information of all groups was taken again at the end of the 8th week.

Main outcomes:

* Dyspnea severity,
* COPD general conditions and
* Fatigue level. The results obtained will be interpreted by comparing between 3 groups.


Eligibility criteria: Inclusion Criteria:

* Diagnosed with COPD for the last 1 year
* Hospitalized for at least 3 days,
* Voluntary patients

Exclusion Criteria:

* Under 18 years old
* Over 85 years old
* Those with chronic fatigue syndrome
* Those with severe heart failure
* Those who had surgery in the last 6 months

Primary outcomes:
measure: Fatigue Level
timeFrame: Applied at baseline and after 8 weeks.
measure: Dyspnea Severity
timeFrame: Applied at baseline and after 8 weeks.
Secondary outcomes:
measure: COPD general condition
timeFrame: Applied at baseline and after 8 weeks.
Other outcomes:
Locations:
city: Kırşehir
country: Turkey
facility: Yasemin CEYHAN
state: Center
Study officials:
affiliation: Kirsehir Ahi Evran Universitesi
name: Yasemin CEYHAN, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02296372: Accuracy, Feasibility and Acceptance of Continuous Glucose Monitoring in Critically Ill Patients
Official title: Pilot Observation of Continuous Glucose Monitoring in Critically Ill Patients Under Consideration of Accuracy, Feasibility and Acceptance by Ward Staff
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Glucose Metabolism Disorders
Diabetic Blood Glucose Monitoring
Critical Illness
Lead sponsor: Charite University, Berlin, Germany
Sponsor class: OTHER
First posted: 2014-11-20
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NON_RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Brief summary: Critically ill patients are on high risk for increased serum glucose levels, leading to more comorbidity and higher mortality risk. In patients with severe sepsis and septic shock hyperglycemia is a typical finding. However the need of insulin therapy is associated with an increased risk of hypoglycemia. Newly developed technologies for continuous glucose monitoring in critically ill patients may improve glycemic control and reduce glucose variability. The investigators will perform continuous glucose monitoring in critically ill patients on ICU. Measurements will be done for a period of 72h per patient. The investigators aim is to evaluate accuracy feasibility and acceptance of these methods. To analyze accuracy sensor glucose levels will be validated due to arterial blood gas measurements with the blood gas analyzer. The investigators will investigate the influence of several factors like oedema, perspiration, BMI, body temperature, pH-value application of vasoconstrictors on accuracy and feasibility of the particular system. Furthermore Nursing staff will be given a questionnaire to identify acceptance.


Eligibility criteria: Inclusion Criteria:

* critically ill patients with expected ICU stay for more than 72 hours
* informed consent by the patients or legal proxy

Exclusion Criteria:

* age \< 18
* no informed consent by the patients or legal proxy
* pregnancy
* infaust prognosis

Primary outcomes:
measure: Accuracy of continuous glucose monitoring compared to blood gas analyses
timeFrame: 72 hours
Secondary outcomes:
measure: Feasibility of continuous glucose monitoring
timeFrame: 72 hours
measure: Acceptance of continuous glucose monitoring by physicians and nursing staff
timeFrame: 72 hours
Other outcomes:
measure: Technical problems with the monitoring
timeFrame: up to 72 hours
Locations:
city: Berlin
country: Germany
facility: Charite University, Berlin, Germany
Study officials:
affiliation: Charite University, Berlin, Germany
name: Steffen Weber-Carstens, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Wollersheim T, Engelhardt LJ, Pachulla J, Moergeli R, Koch S, Spies C, Hiesmayr M, Weber-Carstens S. Accuracy, reliability, feasibility and nurse acceptance of a subcutaneous continuous glucose management system in critically ill patients: a prospective clinical trial. Ann Intensive Care. 2016 Dec;6(1):70. doi: 10.1186/s13613-016-0167-z. Epub 2016 Jul 21.
Clinical trial NCT01366872: Agility LP Ankle Arthroplasty Outcomes
Official title: Agility LP Ankle Arthroplasty: Clinical and Radiographic Outcomes
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Rheumatoid Arthritis of Ankle
Osteoarthritis of Ankle
Traumatic Arthritis of Ankle
Keywords: ankle
arthritis
total ankle arthroplasty
Agility LP,
Lead sponsor: Orthopaedic Associates of Michigan, PC
Sponsor class: OTHER
First posted: 2011-06-06
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Female and male subjects over the age of 18 at the time of procedure who have undergone ankle joint replacement using the DePuy Agility LP Device.

Brief summary: This is a research study which is being done to determine the outcomes following Agility LP ankle replacement. This implant was approved by the FDA in 2007 and has been used since then with good early results. You are being asked to volunteer for this study because you have undergone Total Ankle Arthroplasty with Agility LP prosthesis. The purpose of the study is to compare the range of motion, level of pain and function during daily living prior to and after your ankle surgery.


Eligibility criteria: Inclusion Criteria:

* Over 18 years old
* Can comprehend and sign the informed consent
* Patient must have undergone Agility LP ankle replacement between January 2006 to June 2008

Exclusion Criteria:

* Patient has had following procedures on the study limb within two years of TAA
* Revision of TAA
* Ankle arthrodesis
* Amputation
* Agility LP arthroplasty was done as a revision procedure for a failed TAA or as a takedown of ankle fusion.
* Any condition that, in the opinion of the investigator, makes the patient unsuitable for participation in the study.

Primary outcomes:
measure: Assessment of Functional Outcomes Following Agility LP Ankle Replacement
timeFrame: A Minimum of 2 Years Post Index Procedure
Secondary outcomes:
measure: Evaluation of Complication and Reoperation Rates
timeFrame: A Minimum of 2 Years Post Index Procedure
measure: Radiographic Predictors of Implant Failures and Poor Outcomes
timeFrame: A Minimum of 2 Years Post Index Procedure
Other outcomes:
Locations:
city: Grand Rapids
country: United States
facility: Orthopaedic Associates of Michigan, PC
state: Michigan
Study officials:
affiliation: Orthopaedic Associates of Michigan, PC
name: John G Anderson, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01196572: Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures
Official title: Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: PHASE4
Conditions: Urethral Strictures
Keywords: stricture
urethra
laser
urethrotomy
holmium
bladder outlet obstruction
Lead sponsor: Sheba Medical Center
Sponsor class: OTHER_GOV
First posted: 2010-09-08
Enrollment: 40
Sex: MALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to determine whether laser internal urethrotomy (IU) is as efficient as cold knife internal urethrotomy for treatment of anterior urethral strictures regarding post operative urination outflow, stricture recurrence rate and possible post- operative complications

Detailed description: The current surgical treatment for anterior urethral stricture includes internal urethrotomy (IU) by cold knife. Recurrence rate after such procedure is quoted as 35-70% in 2 to 5 years follow-up. Possible surgical alternative procedures include: open surgical urethral re-construction, urethral stents usage \& laser IU. According to existing data (Nd-YAG laser- retrospective) the recurrence rate after laser IU is far better comparing to cold knife urethrotomy. The current research intends to address this question using prospective randomized methods.

Eligibility criteria: Inclusion Criteria:

* Men over 18 years old with urethral stricture

Exclusion Criteria:

* S/P urethral reconstruction
* Posterior urethral strictures
* Children

Primary outcomes:
measure: post operative clinical & imaging signs of urinary outflow obstruction or partial obstruction
timeFrame: up to 2 years
Secondary outcomes:
measure: post operative complications
timeFrame: up to 2 years
Other outcomes:
Locations:
city: Ramat-Gan
country: Israel
facility: Sheba_Medical_Center
Study officials:
References:
Clinical trial NCT06668272: Small Changes Clinical Weight Loss Trial
Official title: Small Changes Clinical Weight Loss Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Obesity
Keywords: Small Changes
weight loss
Lead sponsor: The University of Texas Health Science Center, Houston
Sponsor class: OTHER
First posted: 2024-10-31
Enrollment: 52
Sex: ALL
Minimum age (years): 18
Maximum age (years): 70
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to assess the effectiveness of the Small Changes program in facilitating weight loss and to assess treatment effects on body composition, blood markers of metabolic health, and blood pressure, and to assess attrition and compliance


Eligibility criteria: Inclusion Criteria:

* Body Mass Index greater than or equal to 25
* Stable weight with less than a 5% body weight change in the past 3 months.
* Willingness and ability to follow a written dietary plan.
* Ambulatory and capable of attending bi-weekly in-person and phone appointments.
* Must reside in the geographic area for the duration of the 12-week study.
* Clearance for weight loss by their health care provider.

Exclusion Criteria:

* Pregnant or lactating.
* Acute medical conditions such as kidney disease, liver disease, pancreatitis, or cancer.
* A history of bariatric surgery or gastrointestinal resection.
* Current use of anti-obesity medications or diabetes medications, such as Glucagon-like peptide-1 receptor agonists (GLP-1RAs), that induce weight loss.
* A history of commercial weight loss program participation within the last six months.
* A history of anorexia nervosa or other eating disorders.
* A history of anxiety or depression.
* Extreme dietary restrictions or allergies that limit the ability to follow the weight loss plan.

Primary outcomes:
measure: Change in weight
timeFrame: Baseline,12 weeks
Secondary outcomes:
measure: Change in Hemoglobin A1C levels
timeFrame: Baseline, 12 weeks
measure: Change in triglycerides levels
timeFrame: Baseline, 12 weeks
measure: Change in total cholesterol levels
timeFrame: Baseline, 12 weeks
measure: Change in HDL cholesterol levels
timeFrame: Baseline, 12 weeks
measure: Change in fasting blood glucose levels
timeFrame: Baseline, 12 weeks
measure: Change in lean body mass
timeFrame: baseline, week 4, week 8, week 12
measure: Change in fat mass
timeFrame: baseline, week 4, week 8, week 12
measure: Compliance as measured by the percentage of meals that follow the diet plan as reported in a daily food log
timeFrame: From baseline to week 12
measure: Attrition as assessed by number of participants that complete the study
timeFrame: week 12
Other outcomes:
Locations:
city: Houston
country: United States
facility: The University of Texas Health Science Center at Houston
state: Texas
city: Lubbock
country: United States
facility: Texas Tech University
state: Texas
Study officials:
affiliation: The University of Texas Health Science Center, Houston
name: Leah Whigham, PhD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT06847672: Comparison of the Time to Reach End-Tidal Oxygen Value of 90 and Oxygen Reserve Index Decline Times During Preoxygenation in Sarcopenic and Non-Sarcopenic Patients
Official title: Comparison of the Time to Reach End-Tidal Oxygen Value of 90 and Oxygen Reserve Index Decline Times During Preoxygenation in Sarcopenic and Non-Sarcopenic Patients Using the 6-Minute Walk Test
Study type: OBSERVATIONAL
Overall status: NOT_YET_RECRUITING
Conditions: Sarcopenia
Preoxygenation
Oxygen Reserve Index
Lead sponsor: Ankara City Hospital Bilkent
Sponsor class: OTHER
First posted: 2025-02-26
Enrollment: 80
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: 80 patients who agreed to participate in the study and are scheduled for major abdominal oncological surgery will be included in the study.

Brief summary: The purpose of this study is to compare the time required to reach an end-tidal oxygen (EtO2) value of 90% and the time until the Oxygen Reserve Index (ORI) drops below 0.55 during preoxygenation in sarcopenic and non-sarcopenic patients. The study aims to investigate the impact of sarcopenia on the oxygenation process.


Eligibility criteria: Inclusion Criteria:

* Patients who agree to participate in the study.
* Patients scheduled for major abdominal oncologic surgery.

Exclusion Criteria:

* Patients with severe cardiopulmonary disease.
* Patients with walking disabilities.

Primary outcomes:
measure: Time required to reach EtO2 90%
timeFrame: preoperatively
measure: Time until ORI drops below 0.55
timeFrame: preoperatively
Secondary outcomes:
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Ankara City Hospital Bilkent
Study officials:
References:
Clinical trial NCT04654572: The Mechanical Properties of Burned Muscles
Official title: The Investigation of Muscle Mechanical Properties in Burned Patients.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Burns
Muscle Loss
Viscoelastic Properties
Stiffness
Keywords: Burn
muscle
myotonometer
viscoelasticity
stiffness
Lead sponsor: Hasan Kalyoncu University
Sponsor class: OTHER
First posted: 2020-12-04
Enrollment: 37
Sex: ALL
Minimum age (years): 18
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SCREENING

Brief summary: The investigate of mechanical properties of muscles in burned patients.

Detailed description: The hypermetabolic response to severe burn is characterized by muscle protein catabolism. Current opinion states that the hypermetabolic state resolves soon after complete wound closure. Clinically, we have witnessed that burned patient appear to be hypermetabolic and catabolic long after full healing of their wounds. Our goal in this study was to determine muscle mechanical properties (tone, stiffness and elasticity) after burn.

Eligibility criteria: Inclusion Criteria:

* burned patient
* major burn over %20 TBSA

Exclusion Criteria:

* Amputation
* Dead
* Systemic disease and abuse

Primary outcomes:
measure: Stiffness
timeFrame: 6 week
measure: Elasticity
timeFrame: 6 week
measure: Tone
timeFrame: 6 week
Secondary outcomes:
Other outcomes:
Locations:
city: Gaziantep
country: Turkey
facility: Hasan kalyoncu üniversity
Study officials:
References:
citation: Gittings PM, Grisbrook TL, Edgar DW, Wood FM, Wand BM, O'Connell NE. Resistance training for rehabilitation after burn injury: A systematic literature review & meta-analysis. Burns. 2018 Jun;44(4):731-751. doi: 10.1016/j.burns.2017.08.009. Epub 2017 Oct 7.
citation: Porter C, Hardee JP, Herndon DN, Suman OE. The role of exercise in the rehabilitation of patients with severe burns. Exerc Sport Sci Rev. 2015 Jan;43(1):34-40. doi: 10.1249/JES.0000000000000029.
citation: Ianieri G, Saggini R, Marvulli R, Tondi G, Aprile A, Ranieri M, Benedetto G, Altini S, Lancioni GE, Goffredo L, Bellomo RG, Megna M, Megna G. New approach in the assessment of the tone, elasticity and the muscular resistance: nominal scales vs MYOTON. Int J Immunopathol Pharmacol. 2009 Jul-Sep;22(3 Suppl):21-4. doi: 10.1177/03946320090220S304. No abstract available.
Clinical trial NCT05915572: Mulligan Technique on Shoulder Dysfunction
Official title: Effect of Mulligan Technique on Shoulder Dysfunction Post Neck Dissection Surgeries
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Head and Neck Cancer
Keywords: Mulligan Technique
Shoulder Dysfunction
Neck Dissection Surgeries
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2023-06-23
Enrollment: 76
Sex: ALL
Minimum age (years): 30
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: 76 patients suffering from shoulder dysfunction following neck dissection surgeries will participate in this study. The participants will be selected from Damanhur Oncology Center and randomly will be distributed into two groups.

Group (A): 38 patients will receive MWM in plus traditional physiotherapy program 3 sessions per week for 6 weeks.

Group (B): 38 patients will receive traditional physiotherapy program 3 sessions per week for 6 weeks.

Detailed description: 1) Subjects: 76 patients suffering from shoulder dysfunction following neck dissection surgeries will participate in this study. The participants will be selected from Damanhur Oncology Center and randomly will be distributed into two groups.

Group (A): 38 patients will receive MWM in plus traditional physiotherapy program 3 sessions per week for 6 weeks.

Group (B): 38 patients will receive traditional physiotherapy program 3 sessions per week for 6 weeks.

The participants will be selected from Damanhur Oncology Center and randomly will be distributed into two groups equal in number.

2) Equipment:

Therapeutic equipment:

* Mulligan Mobilization Technique: to increase shoulder flexion, abduction, external rotation
* Traditional physical therapy program:

Measurement equipment:

* Digital Goniometer
* Shoulder Pain and Disability Index

Eligibility criteria: Inclusion Criteria:

* Patients' age will be between 30-50 years old.
* Both gender 76 patients will participate in this study.

Exclusion Criteria:

* Patients with rotator cuff tears and other shoulder ligament injuries or tendon calcification.

Primary outcomes:
measure: Digital Goniometer
timeFrame: 6 weeks
Secondary outcomes:
measure: Shoulder Pain and Disability Index
timeFrame: 6 weeks
Other outcomes:
Locations:
city: Giza
country: Egypt
facility: Faculty of Physical Therapy
Study officials:
affiliation: Cairo University
name: Research Ethical Committee Faculty of Physical Therapy
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT03324672: Kinesio Taping and Manual Therapy Efficacity on Lumbar Pain During Pregnancy
Official title: Kinesio Taping and Manual Therapy Efficacity on Lumbar Pain During Pregnancy
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Manual Therapy
Keywords: lumbar pain; pregnancy;
Lead sponsor: Fondation Hôpital Saint-Joseph
Sponsor class: OTHER
First posted: 2017-10-30
Enrollment: 1
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Pregnant women often suffer from lumbar pain , specially during the last semester . Usually physiotherapy and manual therapy on TRIGGER point help them .

But there is also another type of support , the Kinesio-Taping using the pose of a strip which aims to mobilize the muscle without any restriction.

The purpose is to reduce the pain with the combo therapy (TRIGGER point plus Kinesi Taping)


Eligibility criteria: Inclusion Criteria:

* age \> 18
* french speaking
* single pregnancy
* lumbar pain
* EIFEL score\>6
* medical insurance

Exclusion Criteria:

* twins pregnancy
* rachial arthrodesis
* Probable Acrylique allergy
* Psoriasis or other cutaneous problems
* circulatory disorder

Primary outcomes:
measure: French version of Roland-Morris questionnaire in chronic low back pain patients EIFEL Échelle d'Incapacité Fonctionnelle pour l'Évaluation des Lombalgies questionnaire) score
timeFrame: change from week 30 to week 38
Secondary outcomes:
measure: Pain scale
timeFrame: change from week 30 to week 38
Other outcomes:
Locations:
city: Paris
country: France
facility: Groupe Hospitalier Paris Saint Joseph
state: Ile-de-France
Study officials:
affiliation: GHPSJ
name: AZRIA Elie, MD
role: STUDY_DIRECTOR
References: