Clinical trial NCT02977091: Fitness Level in Short Stature Children and After Growth Hormone Treatment
Official title: Fitness Level in Short Stature Children and After Growth Hormone Treatment
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Fitness
Keywords: short stature
fitness
children
Lead sponsor: Meir Medical Center
Sponsor class: OTHER
First posted: 2016-11-30
Enrollment: 50
Sex: ALL
Minimum age (years): 5
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: short stature children

Brief summary: fitness and Physical activity will be evaluate in short stature children, using the Euro Fitness testing and the Wingate anaerobic test. the fitness level will be evaluate in healthy short children and with growth hormone deficiency at base line and after 6 month .

Detailed description: The Euro Fitness testing which is a series of field testing for children evaluating aerobic, strength and flexibility and the Wingate anaerobic test which is a 30 seconds maximum pedaling against resistance on bike for evaluating the anaerobic fitness.

the fitness test will be done in healthy short stature children and in growth hormone deficiency or idiopathic short stature from the endocrine unit in Meir medical center The test will be done at base line and after 6 month . The fitness test in child with growth hormone deficiency will be done before starting GH treatment and 6 month later.

The child will be asked to fill a questioner about his daily physical activity Anthropometric measurement will be taking including weight, height and fat percent. Details about age, sex, tanner stage, indication for growth hormone, dose, insulin growth factor-1 (IGF1) level will be taken from the medical file.

Eligibility criteria: Inclusion Criteria:

* short stature
* Physical healthy
* Mental healthy
* Capable to perform fitness test

Exclusion Criteria:

* Cardiac disease that interfere or risk the child during physical activity
* Respiratory disease that interfere or risk the child during physical activity
* Musculoskeletal disease interfering physical preformance.
* Family history of death for unknown reasons at an early age.
* Uncontroled thyroid diseae

Primary outcomes:
measure: change in fitness level
timeFrame: change of fitness levels from base line and after 6 month in short children
Secondary outcomes:
Other outcomes:
Locations:
city: Kfar Saba
country: Israel
facility: Meir Medical Center endocrine unit
Study officials:
affiliation: senior in pediatric medicine
name: Nitsan Dror, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bar-Or O. The Wingate anaerobic test. An update on methodology, reliability and validity. Sports Med. 1987 Nov-Dec;4(6):381-94. doi: 10.2165/00007256-198704060-00001. No abstract available.
citation: Godin G, Shephard RJ. A simple method to assess exercise behavior in the community. Can J Appl Sport Sci. 1985 Sep;10(3):141-6.
citation: Ranson R, Stratton G, Taylor SR. Digit ratio (2D:4D) and physical fitness (Eurofit test battery) in school children. Early Hum Dev. 2015 May;91(5):327-31. doi: 10.1016/j.earlhumdev.2015.03.005. Epub 2015 Apr 4.