Clinical trial NCT05568004: The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine
Official title: The Effect of Different Exercise Types on Migraine Frequency in Individuals With Migraine :Randomized Controlled Study
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Migraine
Chronic Migraine
Keywords: Headache
Exercise
Resistance exercises
Aerobic exercise
Lead sponsor: Ege University
Sponsor class: OTHER
First posted: 2022-10-05
Enrollment: 32
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: The purpose of this study is to evaluate and compare the effect of different exercise types and combinations on migraine attacks in patients with migraine.


Eligibility criteria: Inclusion Criteria:

* A diagnosis of migraine confirmed by a specialist neurologist according to International Classification of Headache Disorders, 3rd version(ICHD-3)
* Diagnosed as chronic migraine at the time of initial diagnosis (may have turned into episodic migraine under preventive treatment)
* At least 5 migraine attack/month in baseline diary
* No obstacle to exercise in the evaluation made with physical examination and ECG
* Diagnosed with migraine for at least 12 months
* Between the ages of 18-50

Exclusion Criteria:

* Exercising regularly in the last 6 months
* Presence of concomitant internal and neurological diseases
* Anti-psychotic drug use
* Drug, alcohol addiction
* Pregnancy, breastfeeding
* Patients who cannot reach the targeted exercise level

Primary outcomes:
measure: Change in the Number of Days With Migraine (in Migraine Frequency)
timeFrame: Baseline and Week 12 and Week 20
Secondary outcomes:
measure: Average Intensity of Headache
timeFrame: Baseline and Week 12 and Week 20
measure: Anxiety
timeFrame: Baseline and Week 12 and Week 20
measure: Depression
timeFrame: Baseline and Week 12 and Week 20
measure: Migraine Specific Quality of Life
timeFrame: Baseline and Week 12 and Week 20
measure: Aerobic Capacity Measurement V02 Max
timeFrame: Baseline and Week 12 and Week 20
measure: Change in Physical Activity Level
timeFrame: Baseline and Week 12 and Week 20
Other outcomes:
Locations:
city: İzmir
country: Turkey
facility: Ege University Sport Medicine Clinic
state: Bornova
Study officials:
affiliation: Ege University Sport Medicine Clinic
name: Yunus Emre Meydanal
role: PRINCIPAL_INVESTIGATOR
affiliation: Ege University Sport Medicine Clinic
name: Seckin Senısık
role: STUDY_DIRECTOR
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