Clinical trial NCT05574426: Efficacy of Movement Breaks in Real-World Settings
Official title: Efficacy of Movement Breaks in Real-World Settings
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Healthy
Keywords: Exercise Snack
Movement Break
Sedentary Time
Lifestyle Exercise
Physical Activity Breaks
VILPA
Lead sponsor: University of British Columbia
Sponsor class: OTHER
Collaborators: name: Canadian Cancer Society (CCS)
name: Canadian Institutes of Health Research (CIHR)
name: McMaster University
First posted: 2022-10-10
Enrollment: 77
Sex: ALL
Minimum age (years): 40
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Participants will be randomized (1:1 allocation ratio) into Mobility or Cardiovascular movement break groups for 12-weeks. Both groups will perform 3-4 movement breaks on at least 3 days of the week.
Primary purpose: PREVENTION

Brief summary: The purpose of this study is to determine the efficacy of performing "exercise snacks" (short movement breaks throughout the day) on various measures of cardiometabolic health.

Detailed description: After being informed about the study and potential risks, all eligible participants who have provided consent will undergo a baseline visit to assess pre-intervention basic anthropometrics, cardiorespiratory fitness, and provide a blood sample. Participants will then be randomized in a 1:1 ratio to one of two groups: 1) Mobility movement breaks (stretching or range of motion exercises); or 2) Cardiovascular movement breaks (designed to raise heart rate). Both groups will be encouraged to perform 3-4 daily movement breaks on at least 3 days of the week with support from an online platform and app that provides video instructions and reminders to complete the movement breaks. After 12 weeks, participants will be asked to return to the lab for the same testing performed at baseline.

Eligibility criteria: Inclusion Criteria:

1. Physically inactive (performing \<150 minutes of moderate-to-vigorous intensity aerobic exercise per week, assessed by pre-screening Get Active Questionnaire);
2. Body Mass Index: 18.5-30.0 kg/m2;
3. Not currently diagnosed with or being treated for cardiometabolic disease (e.g., coronary artery disease, diabetes);
4. Not a current smoker;
5. Cleared to engage in physical activity using the Get Active Questionnaire and, if applicable, consultation with a Qualified Exercise Professional;
6. Access to a computer, tablet or smartphone for intervention delivery and tracking

Exclusion Criteria:

1. Chronic health condition preventing participation in exercise;
2. Lack of access to internet connection

Primary outcomes:
measure: Change From Baseline in Cardiorespiratory Fitness at 12 Weeks
timeFrame: Baseline and Week 12
Secondary outcomes:
measure: Change From Baseline in Plasma Insulin
timeFrame: Baseline and 12 weeks
measure: Change From Baseline in Plasma Glucose
timeFrame: Baseline and 12 weeks
measure: Change From Baseline in Insulin Resistance
timeFrame: Baseline and 12 weeks
measure: Change From Baseline in Inflammatory Cytokines
timeFrame: Baseline and 12 weeks
measure: Change From Baseline in Body Mass
timeFrame: Baseline and 12 weeks
measure: Change From Baseline in Waist Circumference
timeFrame: Baseline and 12 weeks
measure: Device-Measured Adherence to Movement Breaks
timeFrame: Week 2 and week 11
measure: Self-Reported Adherence to Movement Breaks
timeFrame: Once per week for 12 weeks
measure: Movement Break Enjoyment Assessed by the Exercise Enjoyment Scale (EES)
timeFrame: Immediately following each movement break for entire 12-week intervention
measure: Rating of Perceived Exertion (RPE) Following Movement Breaks
timeFrame: Immediately following each movement break for entire 12-week intervention
Other outcomes:
Locations:
city: Kelowna
country: Canada
facility: University of British Columbia
state: British Columbia
city: Hamilton
country: Canada
facility: McMaster University
state: Ontario
Study officials:
affiliation: University of British Columbia
name: Jonathan Little
role: PRINCIPAL_INVESTIGATOR
References: