Clinical trial NCT01696162: Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain
Official title: Conventional Home Exercise Programs Versus Electronic Home Exercise Versus Artificial Intelligence "Virtual Therapy" for Anterior Knee Pain: a Prospective Randomized Comparative Trial.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Patellofemoral Pain Syndrome
Keywords: Knee pain
Anterior knee pain
Patellofemoral
Patellofemoral syndrome
Runners knee
Lead sponsor: Simpletherapy
Sponsor class: INDUSTRY
First posted: 2012-09-28
Enrollment: 85
Sex: ALL
Minimum age (years): 18
Maximum age (years): 64
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This is a clinical research trial to evaluate the efficacy of delivering exercise therapy for knee pain via the Internet utilizing an algorithm designed to adjust a home exercise program based on user input. The investigators hypothesize that exercise therapy can be delivered safely and effectively with increased participant satisfaction compared to the current standard.


Eligibility criteria: Inclusion Criteria:

* Age 18-64 with anterior knee pain
* Have computer access
* Cleared for exercise by a medical professional, if not possible or a medical professional on the study team over the phone and the PAR-Q (Physical Activity Readiness Questionnaire)
* Have consented to participate in the trial

Exclusion Criteria:

* Age \< 18 or \> 64
* Screened as unsafe for exercise by a medical professional or the, study team and/ or Screened out by the PAR-Q
* Does not consent to the trial

Primary outcomes:
measure: The 3 and 6 week survey data evaluating efficacy of the algorithm
timeFrame: 6 months
Secondary outcomes:
measure: Participant compliance
timeFrame: 6 months
measure: Safety
timeFrame: 6 months
Other outcomes:
Locations:
city: Philadelphia
country: United States
facility: Simpletherapy
state: Pennsylvania
Study officials:
affiliation: Simpletherapy
name: Jonathan P Garino, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Baker KR, Nelson ME, Felson DT, Layne JE, Sarno R, Roubenoff R. The efficacy of home based progressive strength training in older adults with knee osteoarthritis: a randomized controlled trial. J Rheumatol. 2001 Jul;28(7):1655-65.
citation: Margolis SA, Paule RC, Ziegler RG. Ascorbic and dehydroascorbic acids measured in plasma preserved with dithiothreitol or metaphosphoric acid. Clin Chem. 1990 Oct;36(10):1750-5.
citation: Bassett SF, Prapavessis H. Home-based physical therapy intervention with adherence-enhancing strategies versus clinic-based management for patients with ankle sprains. Phys Ther. 2007 Sep;87(9):1132-43. doi: 10.2522/ptj.20060260. Epub 2007 Jul 3.
citation: Crossley K, Bennell K, Green S, Cowan S, McConnell J. Physical therapy for patellofemoral pain: a randomized, double-blinded, placebo-controlled trial. Am J Sports Med. 2002 Nov-Dec;30(6):857-65. doi: 10.1177/03635465020300061701.
citation: Kim TWB, Gay N, Khemka A, Garino J. Internet-Based Exercise Therapy Using Algorithms for Conservative Treatment of Anterior Knee Pain: A Pragmatic Randomized Controlled Trial. JMIR Rehabil Assist Technol. 2016 Dec 14;3(2):e12. doi: 10.2196/rehab.5148.