Clinical trial NCT05403294: Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
Official title: Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Coronary Artery Disease
Cardiometabolic Risk Factors
Cardiac Anesthesia
Cardiac Surgery
Anthropometry
Lead sponsor: TC Erciyes University
Sponsor class: OTHER
First posted: 2022-06-03
Enrollment: 240
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients over the age of 18 who have undergone open heart surgery

Brief summary: Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological studies. It is widely accepted that obesity increases the risk of heart disease and is thought to be a risk factor for adverse outcomes after cardiac surgery. However, recent studies show paradoxical results, wherein obese patients can experience fewer adverse events and lower mortality than patients with normal-low body mass index(BMI) . The discriminative capacity of BMI has been criticized because it cannot distinguish muscle mass from fat mass, or reflect fat distribution . Alternatively, abdominal obesity indices, such as waist circumference (WC) and waist-to-height ratio (WHtR), have been suggested to be better predictor of cardiometabolic abnormalities because they modulate the limitation of BMI. However, they were insufficient in studies.For this reason, scientists turned to find a new anthropometric formula that could better detect obesity-related mortality and morbidity and they developed 2 new methods. Body Shape İndex (ABSI) is calculated using waist circumference, BMI and height parameters. Body Roundness İndex (BRI) is calculated using waist circumference and height parameters. These new indices may reflect visceral adiposity and strongly predict cardiovascular risk, postsurgical outcomes and resource utilisation.


Eligibility criteria: Inclusion Criteria:

* open heart surgery
* voluntary patients

Exclusion Criteria:

* emergency surgery
* off-pump or robotic surgery
* surgery requiring deep hypothermic circulatory arrest
* reluctant patients

Primary outcomes:
measure: mortality
timeFrame: within 30 days of the procedure
measure: postoperative stroke
timeFrame: within 30 days of the procedure
measure: cardiac arrest
timeFrame: within 30 days of the procedure
measure: new atrial fibrillation/flutter
timeFrame: within 30 days of the procedure
measure: permanent rhythm device insertion
timeFrame: within 30 days of the procedure
Secondary outcomes:
measure: prolonged ventilation
timeFrame: within 30 days of the procedure
measure: sepsis /deep sternal infection
timeFrame: within 30 days of the procedure
measure: pulmonary complications
timeFrame: within 30 days of the procedure
measure: renal failure / renal dialysis
timeFrame: within 30 days of the procedure
measure: total intensive care unit (ICU) hours
timeFrame: within 30 days of the procedure
measure: intensive care unit (ICU) readmissions
timeFrame: within 30 days of the procedure
Other outcomes:
Locations:
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