Clinical trial NCT04640701: Obesity in G60 Trauma Patients / Obesity in G60 Trauma Patients
Official title: Obesity in G60 Trauma Patients / Obesity in G60 Trauma Patients
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Obesity
Lead sponsor: Methodist Health System
Sponsor class: OTHER
First posted: 2020-11-23
Enrollment: 100
Sex: ALL
Minimum age (years): 60
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: OTHER
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Records of trauma patients who were admitted to MHS between January1st 2006 and June 30th 2016

Brief summary: Obesity is a national epidemic that affects all aspects of health care, including trauma care. According to the Centers for Disease Control and Prevention, 1% of US adults 20 years old and older are obese (body mass index \[BMI\], calculated as weight in kilograms divided by height in meters squared, \> 30), and 69% are overweight (BMI \> 25) (1, 2). Obesity is a major health concern because of its established relationship with serious medical diseases and increased likelihood of comorbid conditions (eg, diabetes mellitus, hyperlipidemia, heart disease, pulmonary disease) (3). As the number of obese adults continues to increase, the potential number of obese trauma patients with severe injury and complications will also increase (3). Management of prehospital and in-hospital trauma care, including complications associated with airway management, surgical procedures, and radiological imaging, of obese patients can be challenging. However, published reports on how obesity complicates hospital stays after trauma are conflicting (4, 5). Several studies have indicated that obese trauma patients are more likely than non-obese patients to have longer stays in the intensive care unit (ICU) and hospital, more days of mechanical ventilation, more complications, and comorbid conditions, and higher mortality (6,7,8). Other studies have indicated no differences between obese and nonobese patients in mortality, length of stay in the ICU and the hospital, duration of mechanical ventilation, complications, or comorbid conditions (9). Accordingly, the main aim of this study is to investigate and compare hospital course, clinical outcomes, disposition, and the cost of treatment between geriatric obese and non-obese patients hospitalized for treatment of traumatic injuries.

Detailed description: This proposed research is a retrospective chart review to determine if trauma patients with different body mass indexes differed in hospital course, clinical outcomes, disposition, and the cost of treatment.

Records of trauma patients who were admitted to MHS between January1st 2006 and June 30th 2016 will be retrieved to review the clinical charts according to the investigator's inclusion and exclusion criteria.

Basic demographics and clinical outcomes parameters as noted above will be attained from the patient's medical records.

Eligibility criteria: Inclusion Criteria:

1. Male and female patient's ≥ 60 years of age.
2. Blunt and penetration injury.

Exclusion Criteria:

1. Pregnant and breastfeeding women.
2. Patients \< 60 years of age

Primary outcomes:
measure: Obesity's effect on the outcomes of geriatric trauma patients
timeFrame: January1st 2006 and June 30th 2016
Secondary outcomes:
measure: Body mass index
timeFrame: January1st 2006 and June 30th 2016
measure: Length of stay
timeFrame: January1st 2006 and June 30th 2016
measure: Injury severity score
timeFrame: January1st 2006 and June 30th 2016
Other outcomes:
Locations:
city: Dallas
country: United States
facility: Methodist Dallas Medical Center
state: Texas
Study officials:
affiliation: The Methodist Hospital Research Institute
name: Michael Truitt, M.D.
role: PRINCIPAL_INVESTIGATOR
References: