Clinical trial NCT03299504: Factors Predicting Success in Lung Transplant Recipients Who Have Undergone Intensive Post-operative Rehabilitation
Official title: Factors Predicting Success in Lung Transplant Recipients Who Have Participated in the COLTT Program (Daily Intensive Post-hospitalization Rehabilitation): A Retrospective Review
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Lung Transplant
Lead sponsor: Indiana University Health Methodist Hospital
Sponsor class: OTHER
First posted: 2017-10-03
Enrollment: 105
Sex: ALL
Minimum age (years): 18
Maximum age (years): 80
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Lung transplant recipients at IU Health Methodist Hospital. As part of standard care, all patients who survive to hospital discharge are referred by transplant pulmonologists to the COLTT program.

Brief summary: This is a retrospective review of the COLTT program outcomes and factors that predict recovery of functional status after lung transplantation.

Detailed description: The Center of Life for Thoracic Transplant (COLTT) program is a daily (5 days per week) intensive rehabilitation program for patients who have undergone lung transplant. Patients are enrolled in COLTT as part of standard care after hospital discharge. This study is a retrospective review of seventy patients that measures the efficacy of the COLTT program and establishes predictors of patient success.This study will also measure the effect of functional outcomes on hospital readmission post COLTT discharge.

Eligibility criteria: Inclusion Criteria:

* All patients who completed the COLTT program from May, 2016 to July, 2017.

Exclusion Criteria:

* Any COLTT patients who were not new lung transplant recipients.

Primary outcomes:
measure: Time to reach program goals (days)
timeFrame: Through study completion, an average of 4 weeks
Secondary outcomes:
measure: Gait speed (mph, % expected)
timeFrame: Through study completion, an average of 4 weeks
measure: Single leg stance performance (seconds, % expected)
timeFrame: Through study completion, an average of 4 weeks
measure: One-minute sit to stand performance (number, % expected)
timeFrame: Through study completion, an average of 4 weeks
measure: Six minute walk distance (feet, % expected)
timeFrame: Through study completion, an average of 4 weeks
Other outcomes:
measure: Hospital readmission
timeFrame: 6 months
Locations:
city: Indianapolis
country: United States
facility: IU Health Methodist Hospital
state: Indiana
Study officials:
References:
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citation: Springer BA, Marin R, Cyhan T, Roberts H, Gill NW. Normative values for the unipedal stance test with eyes open and closed. J Geriatr Phys Ther. 2007;30(1):8-15. doi: 10.1519/00139143-200704000-00003.
citation: Middleton A, Fritz SL, Lusardi M. Walking speed: the functional vital sign. J Aging Phys Act. 2015 Apr;23(2):314-22. doi: 10.1123/japa.2013-0236. Epub 2014 May 2.
citation: Dierich M, Tecklenburg A, Fuehner T, Tegtbur U, Welte T, Haverich A, Warnecke G, Gottlieb J. The influence of clinical course after lung transplantation on rehabilitation success. Transpl Int. 2013 Mar;26(3):322-30. doi: 10.1111/tri.12048. Epub 2013 Jan 7.