Clinical trial NCT05476926: A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
Official title: Real-World, Long-Term Data Collection to Gain Clinical Insights Into Roche Ophthalmology Products (VOYAGER STUDY)
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Neovascular Age-related Macular Degeneration
Diabetic Macular Edema
Retinal Vein Occlusion
Branch Retinal Vein Occlusion
Central Retinal Vein Occlusion
Hemi-retinal Vein Occlusion
Lead sponsor: Hoffmann-La Roche
Sponsor class: INDUSTRY
First posted: 2022-07-27
Enrollment: 6000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients being treated with specified Roche ophthalmology products approved in retinal indications in real-world, routine clinical practice.

Brief summary: The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products in approved retinal indications (Faricimab for neovascular age-related macular degeneration \[nAMD\], diabetic macular edema \[DME\], and retinal vein occlusion; Port Delivery System with Ranibizumab for nAMD) in routine clinical practice. This study will not provide or make recommendations on use of any products including Roche products; treatment decisions will be determined by the treating physician and must be made independently to the decision to participate in this study. Participation in this study will not change or influence a patient's standard of care in any way.


Eligibility criteria: Inclusion Criteria:

1. Have provided informed consent, as required per local regulations 2.a) Adult patient, as defined by local regulations and local product label, who is newly initiating treatment (or initiated treatment in the previous visit) with a specified approved Roche ophthalmology product in retinal indication of interest for this study in at least one eye, according to the investigator's discretion in routine clinical practice; OR 2.b) Adult patient, as defined by local regulations and local product label, who is continuing treatment with any specified approved Roche ophthalmology product in retinal indication of interest for this study in at least one eye after initiating that treatment in a Roche interventional trial.

Exclusion Criteria:

1. Concomitant participation of the patient in an investigational ophthalmology clinical trial that includes receipt of any investigational drug or procedure within the last 28 days prior to enrollment (this restriction does not apply to patients who are rolling over from Roche interventional studies and continuing treatment with any specified approved Roche ophthalmology product in retinal indication of interest for this study)

Primary outcomes:
measure: Change in Visual Acuity from Baseline at 1 Year, per Approved Retinal Indication and Product
timeFrame: Baseline and 1 year
Secondary outcomes:
measure: Change in Visual Acuity from Baseline Over Time, per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Percentage of Eyes on Each Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other) Over Time, per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Number of Treatments Over Time, per Approved Retinal Indication and Product
timeFrame: At 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Cumulative Time Spent on Each Treatment per Eye, Overall and per Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other), per Approved Retinal Indication and Product
timeFrame: From Baseline until end of study (up to 5 years)
measure: Percentage of Eyes with Treatment Switch by Reason for Switch Over Time, per Approved Retinal Indication and Product
timeFrame: At 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Percentage of Eyes with Treatment Regimen Switch (Fixed, Treat-and-Extend, As Needed, or Other) by Reason for Switch Over Time, per Approved Retinal Indication and Product
timeFrame: At 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Total Number of Visits per Year, per Approved Retinal Indication and Product
timeFrame: Annually (up to 5 years)
measure: Number of Visits With or Without Treatment per Year, per Approved Retinal Indication and Product
timeFrame: Annually (up to 5 years)
measure: Time Interval Between Treatments per Year, per Approved Retinal Indication and Product
timeFrame: Annually (up to 5 years)
measure: Number of Eyes Treated with Ocular Concomitant and Subsequent Medications by Type and Frequency During the Study, per Approved Retinal Indication and Product
timeFrame: From Baseline until end of study (up to 5 years)
measure: Change in Visual Acuity from Baseline Over Time, According to Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other), per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Change in Visual Acuity from Baseline Over Time, According to Number of Treatments, per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Change in Visual Acuity from Baseline Over Time, According to Total Number of Visits, per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Change in Visual Acuity from Baseline Over Time, According to Treatment Schedule, per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Change in Central Subfield Thickness (CST) from Baseline Over Time, per Approved Retinal Indication and Product
timeFrame: Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
measure: Number of Participants with at Least One Ocular Adverse Event, by Severity and Seriousness, per Approved Retinal Indication and Product
timeFrame: From Baseline until end of study (up to 5 years)
measure: Number of Participants with at Least One Non-Ocular Adverse Event, by Severity and Seriousness, per Approved Retinal Indication and Product
timeFrame: From Baseline until end of study (up to 5 years)
Other outcomes:
Locations:
city: Phoenix
country: United States
facility: Retinal Research Institute, LLC
state: Arizona
city: Beverly Hills
country: United States
facility: Retina-Vitreous Associates Medical Group
state: California
city: Pasadena
country: United States
facility: California Eye Specialists Medical group Inc.
state: California
city: Sacramento
country: United States
facility: Retinal Consultants Medical Group
state: California
city: Coral Springs
country: United States
facility: Advanced Research
state: Florida
city: Pensacola
country: United States
facility: Retina Specialty Institute
state: Florida
city: Lemont
country: United States
facility: University Retina and Macula Associates, PC
state: Illinois
city: Springfield
country: United States
facility: Springfield Clinic, Llp
state: Illinois
city: Lexington
country: United States
facility: Retina Associates of Kentucky
state: Kentucky
city: Hagerstown
country: United States
facility: Cumberland Valley Retina Consultants PC
state: Maryland
city: Royal Oak
country: United States
facility: Associated Retinal Consultants PC
state: Michigan
city: Erie
country: United States
facility: Erie Retinal Surgery
state: Pennsylvania
city: Florence
country: United States
facility: Palmetto Retina Center
state: South Carolina
city: Nashville
country: United States
facility: Tennessee Retina PC
state: Tennessee
city: San Antonio
country: United States
facility: Brown Retina Institute
state: Texas
city: Salt Lake City
country: United States
facility: University of Utah, John Moran Eye Center
state: Utah
city: Lynchburg
country: United States
facility: Piedmont Eye Center
state: Virginia
city: Norfolk
country: United States
facility: Wagner Macula and Retina Center
state: Virginia
city: Spokane
country: United States
facility: Spokane Eye Clinical Research
state: Washington
city: Ciudad Autonoma de Buenos Aires
country: Argentina
facility: Salud Ocular
state: Buenos Aires
city: Ciudad Autonoma Buenos Aires
country: Argentina
facility: Centro Oftalmologico Dr. Charles S.A.
city: Cordoba
country: Argentina
facility: Centro Privado de Ojos Romagosa S.A
city: San Miguel de Tucuman
country: Argentina
facility: CEO Centro de Especialidades Oftalmologicas Tucuman
city: Hurstville
country: Australia
facility: Retina and Macula Specialists
state: New South Wales
city: Westmead
country: Australia
facility: Sydney West Retina
state: New South Wales
city: Geebung
country: Australia
facility: Sunshine Coast University Hospital
state: Queensland
city: East Melbourne
country: Australia
facility: Centre For Eye Research Australia
state: Victoria
city: East Melbourne
country: Australia
facility: East Melbourne Eye Group
state: Victoria
city: Malvern
country: Australia
facility: Cabrini Hospital Malvern
state: Victoria
city: Broome
country: Australia
facility: Lions Outback Vision Service in Broome
state: Western Australia
city: Nedlands
country: Australia
facility: The Lions Eye Institute
state: Western Australia
city: Sofia
country: Bulgaria
facility: Medical Center for Eye Health ? Focus Ltd
city: Sofia
country: Bulgaria
facility: Specialized Eye Hospital Pentagram
city: Varna
country: Bulgaria
facility: Eye Clinic St. Petka - Varna
city: Varna
country: Bulgaria
facility: SHEDAT - Varna EOOD
city: New Westminster
country: Canada
facility: Retina Surgical Associates
state: British Columbia
city: Hamilton
country: Canada
facility: St Joseph's Centre for Mountain Health Services
state: Ontario
city: London
country: Canada
facility: St. Joseph's Health Care - London
state: Ontario
city: Ottawa
country: Canada
facility: Retina Institute of Ottawa
state: Ontario
city: Toronto
country: Canada
facility: Toronto Retina Institute
state: Ontario
city: Vaughan
country: Canada
facility: Clarity eye Institute
state: Ontario
city: Boisbriand
country: Canada
facility: Institut De L'Oeil Des Laurentides
state: Quebec
city: Montreal
country: Canada
facility: Clinique d'ophtalmologie et de Retine de l'est
state: Quebec
city: Montreal
country: Canada
facility: Eye Health MD (Opthalmology)
state: Quebec
city: Sainte-catherine
country: Canada
facility: Retina MD Clinic
state: Quebec
city: Quebec
country: Canada
facility: Centre Oculaire de Quebec
city: Las Condes
country: Chile
facility: Centro de la Vision
city: Metropolitana
country: Chile
facility: Red Salud UC Christus
city: Vitacura
country: Chile
facility: Fundacion Oftalmologica Los Andes
city: Osijek
country: Croatia
facility: Clinical Hospital Centre Osijek
city: Rijeka
country: Croatia
facility: Clinical Hospital Centre Rijeka
city: Zagreb
country: Croatia
facility: Special Hospital for Ophthalmology Svjetlost
city: Glostrup
country: Denmark
facility: Rigshospitalet Glostrup
city: Marseille
country: France
facility: CH St Joseph
state: Bouches Du Rh(ne
city: Dijon Cedex
country: France
facility: CHU Dijon - Hopital Francois Mitterrand
state: Cte-d'Or
city: Bordeaux
country: France
facility: Groupe Hospitalier Pellegrin
state: Gironde
city: Nantes Cedex 1
country: France
facility: CHU de Nantes - Hotel Dieu
state: Loire Atlantique
city: Saint Etienne
country: France
facility: CHU de St-Etienne - Hopital Nord
state: Loire
city: Nantes
country: France
facility: Institut Ophtalmologique De l Ouest Jules Verne
state: Paris
city: Lyon Cedex 04
country: France
facility: Centre Hospitalier de la Croix Rousse
state: Rhone
city: Lyon
country: France
facility: Hopital Edouard Herriot - CHU Lyon
state: Rhone
city: Amiens Cedex 01
country: France
facility: CHU Amiens Picardie, Centre de Recherche Clinique
state: Somme
city: Le Chesnay Cedex
country: France
facility: Centre Hospitalier de Versailles
state: Yvelines
city: Aix En Provence
country: France
facility: Aix Vision
city: Bordeaux Floirac
country: France
facility: Clinique des Yeux Bordeaux
city: Bordeaux
country: France
facility: Centre Rétine Gallien
city: Creteil cedex
country: France
facility: Centre Hospitalier Intercommunal de Créteil
city: Ecully
country: France
facility: Clinique du Val d'Ouest- Institut Rhône Alpin
city: Grenoble
country: France
facility: Centre Optha Du Dauphine
city: La Rochelle cedex
country: France
facility: Hôpital Saint-Louis - La Rochelle
city: Lagord
country: France
facility: Visiopole Private Practice
city: Lyon
country: France
facility: Centre Ophtalmologique Rabelais
city: Lyon
country: France
facility: Centre Ophtalmologique Kleber
city: Marseille
country: France
facility: Centre Monticelli Paradis d Ophtalmologie
city: Montargis
country: France
facility: Clinique de Montargis
city: Montauban
country: France
facility: Clinique Honore Cave
city: Montbonnot-Saint-Martin
country: France
facility: Alpes Retine
city: Montpellier
country: France
facility: Centre Des Arceaux
city: Nice
country: France
facility: CHU Nice - Hôpital Saint Roch
city: Osny
country: France
facility: OPH95
city: Paris
country: France
facility: Centre Ophtalmologique de L'Odeon
city: Paris
country: France
facility: Centre Ophtalmologique d?Imagerie et de Laser
city: Poities Cedex
country: France
facility: CHU Poitiers - Hôpital la Milétrie
city: Saint-jean
country: France
facility: Clinique de l'Union
city: St Cyr Sur Loire
country: France
facility: Centre St Exupery
city: St Herblain
country: France
facility: Institut Sourdille
city: Toulouse
country: France
facility: Chu Toulouse
city: Koeln
country: Germany
facility: Universitaetsklinikum Koeln
state: Nordrhein Westfalen
city: Berlin
country: Germany
facility: St. Gertrauden Krankenhaus Berlin, Augenheilkunde
city: Berlin
country: Germany
facility: Charité Universitätsmedizin Berlin
city: Chemnitz
country: Germany
facility: Klinikum Chemnitz gGmbH
city: Dessau - Roßlau
country: Germany
facility: Martin-Luther-Universitaet Halle-Wittenberg - Staedtisches Klinikum Dessau (SKD)
city: Dresden
country: Germany
facility: Universitaetsklinikum Carl Gustav Carus TU Dresden
city: Frankfurt
country: Germany
facility: Klinikum der Johann Wolfgang Goethe-Universitaet
city: Frankfurt
country: Germany
facility: Universitaetsklinikum Frankfurt Goethe-Universitaet
city: Greifswald
country: Germany
facility: Universitaetsmedizin Greifswald
city: Halle
country: Germany
facility: Universitaetsklinikum Halle (Saale)
city: Hannover
country: Germany
facility: Medizinische Hochschule Hannover
city: Heidelberg
country: Germany
facility: Universitaetsklinikum Heidelberg
city: Leipzig
country: Germany
facility: Universitaetsklinikum Leipzig
city: Ludwigshafen
country: Germany
facility: Apotheke am Klinikum Ludwigshafen
city: Magdeburg
country: Germany
facility: Universitaetsklinikum Magdeburg A.oe.R
city: Mannheim
country: Germany
facility: Universitätsklinikum Mannheim
city: Rostock
country: Germany
facility: Praxis Dr. Amin Gamael
city: Rostock
country: Germany
facility: Universitaetsaugenklinik Rostock
city: Sulzbach
country: Germany
facility: Knappschaftskrankenhaus Sulzbach
city: Würzburg
country: Germany
facility: Private Practice of Dr. Astrid Sader Moritz
city: Hong Kong
country: Hong Kong
facility: Grantham Hospital
city: Mongkok
country: Hong Kong
facility: Hong Kong Eye Hospital
city: Haifa
country: Israel
facility: Rambam Health Care Campus
city: Holon
country: Israel
facility: Wolfson Medical Center
city: Jerusalem
country: Israel
facility: Hadassah
city: Kfar- Saba
country: Israel
facility: Meir Medical Center
city: Petah Tikva
country: Israel
facility: Rabin MC
city: Tel Aviv
country: Israel
facility: Tel-Aviv Sourasky Medical Center
city: Catanzaro
country: Italy
facility: Azienda Ospedaliero Universitaria Mater Domini
state: Calabria
city: Napoli
country: Italy
facility: Ospedale Monaldi - AORN dei Colli
state: Campania
city: Udine
country: Italy
facility: Azienda Ospedaliera di Udine Ospedale S. Maria della Misericordia
state: Friuli-Venezia Giulia
city: Roma
country: Italy
facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
state: Lazio
city: Roma
country: Italy
facility: Azienda Ospedaliera Sant'Andrea-Universitr di Roma La Sapien
state: Lazio
city: Genova
country: Italy
facility: IRCCS Ospedale Policlinico San Martino
state: Liguria
city: Milano
country: Italy
facility: Ospedale San Raffaele
state: Lombardia
city: Vimercate
country: Italy
facility: Azienda Ospedaliera Desio
state: Lombardia
city: Acquaviva Delle Fonti
country: Italy
facility: Ente Ecclesiastico Ospedale Generale Regionale F Miulli
state: Piemonte
city: Torino
country: Italy
facility: Ospedale Oftalmico
state: Piemonte
city: Torino
country: Italy
facility: Città della Salute e della Scienza di Torino. Presidio Molinette
state: Piemonte
city: Torino
country: Italy
facility: Ospedale Mauriziano Umberto I
state: Piemonte
city: Bari
country: Italy
facility: Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
state: Puglia
city: Sassuolo
country: Italy
facility: Ospedale Di Sassuolo
state: Sardegna
city: Catania
country: Italy
facility: Azienda Ospedaliera Universitaria "Policlinico - Vittorio Emanuele" (Presidio Gaspare Rodolico)
state: Sicilia
city: Palermo
country: Italy
facility: Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
state: Sicilia
city: Aichi
country: Japan
facility: Chukyo Hospital
city: Aichi
country: Japan
facility: Nagoya City University Hospital
city: Aichi
country: Japan
facility: Aichi Medical University Hospital
city: Akita-shi
country: Japan
facility: Akita University Hospital
city: Chiba
country: Japan
facility: Chiba University Hospital
city: Chiba
country: Japan
facility: Juntendo University Urayasu Hospital
city: Chiba
country: Japan
facility: Toho University Sakura Medical Center
city: Chuo-shi
country: Japan
facility: University of Yamanashi Hospital
city: Fukuoka
country: Japan
facility: Kyushu University Hospital
city: Fukuoka
country: Japan
facility: Kurume University Hospital
city: Gifu-shi
country: Japan
facility: Gifu University Hospital
city: Hiroshima
country: Japan
facility: Hiroshima University Hospital
city: Hokkaido
country: Japan
facility: Sapporo City General Hospital
city: Hokkaido
country: Japan
facility: Hokkaido University Hospital
city: Hyogo
country: Japan
facility: Kobe University Hospital
city: Ibaraki
country: Japan
facility: University of Tsukuba Hospital
city: Ibaraki
country: Japan
facility: Kozawa eye hospital and diabetes center
city: Kagawa
country: Japan
facility: Kagawa University Hospital
city: Kanagawa
country: Japan
facility: Yokohama City University Medical Center
city: Meguro-ku
country: Japan
facility: NHO Tokyo Medical Center
city: Mie
country: Japan
facility: Mie University Hospital
city: Miyagi
country: Japan
facility: Fukushima Medical University Hospital
city: Nagano
country: Japan
facility: Shinshu University Hospital
city: Nagasaki
country: Japan
facility: Nagasaki University Hospital
city: Nagasaki
country: Japan
facility: Japanese Red Cross Nagasaki Genbaku Hospital
city: Osaka-shi
country: Japan
facility: Tazuke-kofukai Medical Research Institute Kitano Hospital
city: Osaka
country: Japan
facility: Osaka Metropolitan University Hospital
city: Osaka
country: Japan
facility: Kansai Medical University Hospital
city: Saitama
country: Japan
facility: Saitama Medical University Hospital
city: Shiga
country: Japan
facility: Shiga University Of Medical Science Hospital
city: Shizuoka
country: Japan
facility: Seirei Hamamatsu General Hospital
city: Suita
country: Japan
facility: Osaka University Hospital
city: Takatsuki-shi
country: Japan
facility: Osaka Medical and Pharmaceutical University Hospital
city: Tokushima
country: Japan
facility: Tokushima University Hospital
city: Tokyo
country: Japan
facility: Nihon University Hospital
city: Tokyo
country: Japan
facility: Juntendo University Hospital
city: Tokyo
country: Japan
facility: Keio University Hospital
city: Tokyo
country: Japan
facility: Tokyo Women's Medical University Hospital
city: Tokyo
country: Japan
facility: Kyorin University Hospital
city: Toyoake-shi
country: Japan
facility: Fujita Health University Hospital
city: Yamagata
country: Japan
facility: Yamagata University Hospital
city: Yamaguchi
country: Japan
facility: Yamaguchi University Hospital
city: Yoshida-gun
country: Japan
facility: University of Fukui Hospital
city: Arecibo
country: Puerto Rico
facility: Emanuelli Research and Development Center
city: Singapore
country: Singapore
facility: National University Hospital
city: Singapore
country: Singapore
facility: Singapore National Eye Centre
city: Singapore
country: Singapore
facility: Eye & Retina Surgeons
city: Singapore
country: Singapore
facility: Tan Tock Seng Hospital
city: Singapore
country: Singapore
facility: Eagle Eye Centre
city: Granollers
country: Spain
facility: Fundacio Privada Hospital Asil de Granollers
state: Barcelona
city: L' Hospitalet DE Llobregat
country: Spain
facility: Hospital Universitari de Bellvitge
state: Barcelona
city: Palma de Mallorca
country: Spain
facility: Hospital Universitari Son Espases
state: Islas Baleares
city: Ferrol
country: Spain
facility: Complejo Hospitalario Universitario de Ferrol
state: LA Coruna
city: Santiago de Compostela
country: Spain
facility: Complejo Hospitalario Universitario de Santiago.
state: LA Coruna
city: Logroño
country: Spain
facility: Complejo Hospitalario San Millán y San Pedro De La Rioja
state: LA Rioja
city: Las Palmas de Gran Canaria
country: Spain
facility: Hospital Universitario Insular de Gran Canaria
state: LAS Palmas
city: Marbella
country: Spain
facility: Hospital Costa del Sol
state: Malaga
city: Vigo
country: Spain
facility: Hospital Xeral-Cies de Vigo
state: Pontevedra
city: Santa Cruz de Tenerife
country: Spain
facility: Hospital Universitario Nuestra Señora de la Candelaria
state: Tenerife
city: Bilbao
country: Spain
facility: Hospital de Basurto
state: Vizcaya
city: Albacete
country: Spain
facility: Complejo Hospitalario Universitario de Albacete
city: Barcelona
country: Spain
facility: Hospital de la Santa Creu i Sant Pau
city: Barcelona
country: Spain
facility: Hospital Dos de Maig
city: Barcelona
country: Spain
facility: Hospital Universitari Vall dHebron (CEMCAT)
city: Barcelona
country: Spain
facility: Hospital Clinic de Barcelona
city: Burgos
country: Spain
facility: Complejo Asistencial Universitario de Burgos
city: Cadiz
country: Spain
facility: Hospital Universitario Puerta del Mar
city: Cordoba
country: Spain
facility: Hospital Universitario Reina Sofia
city: Granada
country: Spain
facility: Hospital Universitario Virgen de Las Nieves
city: Malaga
country: Spain
facility: Hospital Carlos Haya
city: Murcia
country: Spain
facility: Hospital Universitario Virgen de La Arrixaca
city: Sevilla
country: Spain
facility: Hospital Universitario Virgen Del Rocio Sevila
city: Valladolid
country: Spain
facility: Hospital Universitario Rio Hortega
city: Zaragoza
country: Spain
facility: Hospital Universitario Miguel Servet
city: Aarau
country: Switzerland
facility: Kantonsspital Aarau AG
city: Bern
country: Switzerland
facility: Inselspital-Universitaetsspital Bern
city: Binningen
country: Switzerland
facility: Vista Augenklinik Binningen
city: Lausanne
country: Switzerland
facility: Hôpital ophtalmique Jules-Gonin
city: Lausanne
country: Switzerland
facility: Swiss Visio Montchoisi
city: Lugano
country: Switzerland
facility: Ospedale Regionale di Lugano
city: Luzern
country: Switzerland
facility: Luzerner Kantonsspital Luzern
city: Zürich
country: Switzerland
facility: Stadtspital Triemli
city: Abu dhabi
country: United Arab Emirates
facility: Burjeel Hopital
city: Dubai
country: United Arab Emirates
facility: Medcare Eye Center - Dubai
city: Bedford
country: United Kingdom
facility: Bedford Hospital
city: Belfast
country: United Kingdom
facility: Mater Infirmorum Hospital
city: Birmingham
country: United Kingdom
facility: Birmingham Midland Eye Centre
city: Bradford
country: United Kingdom
facility: Bradford Royal Infirmary
city: Bristol
country: United Kingdom
facility: Bristol Eye Hospital
city: Cardiff
country: United Kingdom
facility: University Hospital of Wales
city: Cheltenham
country: United Kingdom
facility: Cheltenham General Hospital
city: Colchester
country: United Kingdom
facility: Essex County Hospital
city: Coventry
country: United Kingdom
facility: University Hospitals Coventry and Warwickshire NHS Trust
city: Frimley
country: United Kingdom
facility: Frimley Park Hospital
city: Harrow
country: United Kingdom
facility: North West London Hospitals NHS Trust
city: Hull
country: United Kingdom
facility: Hull Royal Infirmary
city: Leeds
country: United Kingdom
facility: St James University Hospital
city: Liverpool
country: United Kingdom
facility: Royal Liverpool University Hospital
city: London
country: United Kingdom
facility: Moorfields Eye Hospital
city: London
country: United Kingdom
facility: Royal Free Hospital
city: London
country: United Kingdom
facility: Kings College Hospital
city: Maidstone, Kent
country: United Kingdom
facility: Maidstone Hospital
city: Manchester
country: United Kingdom
facility: Manchester Royal Eye Hospital
city: Newcastle upon Tyne
country: United Kingdom
facility: Royal Victoria Infirmary
city: Norfolk
country: United Kingdom
facility: James Paget University Hospitals NHS Foundation Trust
city: Oxford
country: United Kingdom
facility: John Radcliffe Hospital
city: Sheffield
country: United Kingdom
facility: Royal Hallamshire Hospital
city: Southampton
country: United Kingdom
facility: Southampton General Hospital
city: Sunderland
country: United Kingdom
facility: Sunderland Eye Infirmary
city: Torquay
country: United Kingdom
facility: Torbay Hospital
city: Wolverhampton
country: United Kingdom
facility: The Royal Wolverhampton Hospitals NHS Trust
Study officials:
affiliation: Hoffmann-La Roche
name: Clinical Trials
role: STUDY_DIRECTOR
References: