Clinical trial NCT06925191: Assessment of Torso Musculature and Hamstring Flexibility in Patients With Chronic Ankle Instability
Official title: Assessment of Hamstring Flexibility, Static and Dynamic Core Muscles Endurance in Patients With Chronic Ankle Instability
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Chronic Ankle Instability, CAI
Keywords: hamstring flexibility
90-90 active knee extension
torso musculature
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2025-04-13
Enrollment: 58
Sex: ALL
Minimum age (years): 20
Maximum age (years): 35
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: 29 healthy people and 29 non-healthy people with chronic ankle instability

Brief summary: The purpose of this study is to assess torso musculature in terms of static and dynamic core muscle endurance tests and hamstring flexibility in non-athletic patients with unilateral chronic ankle instability.

Detailed description: Ankle sprains are extremely common in public as well as in sports. Most people with acute ankle sprains respond well to conservative treatment , but many may experience chronic ankle pain and instability .

Injuries to the ankle lateral ligament typically occur when the ankle joint is inverted and plantar flexed . Ankle sprains occur about seven times per 1000 person-years in the general population, and in highly active people, the incidence can reach 45 times per 1000 person-years .

Chronic ankle instability (CAI), which includes both functional and mechanical ankle instability, is characterized by recurrent ankle sprains, persistent symptoms, and a tendency to "giving way" .

The terms mechanical ankle instability (MAI) and functional ankle instability (FAI) refer to two different conditions: FAI is defined as recurrent ankle sprains or re-damage, while MAI is defined as a state of ligament relaxation detected by objective physical examinations of the talar tilt and anterior drawer sign. The complaint of subjective feelings, such as ankle giving away in FI, is associated with FAI .

In relation to postural stability, which is characterized as the capacity to sustain and regulate one's center of gravity over a support base, postural control is a complicated process that arises from the cooperation and synergy of the vestibular, ocular, and somatosensory systems. Moreover, lower limb injuries are thought to be associated with postural instability.

In the kinetic chain that runs from the foot to the lumbar spine, core stability has been emphasized as a crucial factor to keep in mind when preserving dynamic joint stability .

It is important to note that in this instance, core stability refers to the hip complex's ability to maintain homeostasis following a disturbance and to avoid buckling. Additionally, there is clear evidence linking lower limb movement to trunk muscle activity . Motor chain disruptions resulting from dysfunction in the trunk, pelvis, and hips can cause lower extremity injuries and lower back pain (LBP) .

Additionally, the torso musculature was measured by testing the endurance of the core muscles (static and dynamic). The Bench Trunk Curl-Up test (BTCT) was used to measure dynamic endurance, while the modified right side-bridge, modified left side-bridge, trunk flexion and horizontal back extension tests were used for static endurance (the endurance time of each isometric test was recorded).

In addition to disorders including low back discomfort and irregular gait, tight hamstrings are linked to dysfunction in the lumbar spine, pelvis, and lower limb .

Tight hamstrings are linked to poor motor control patterns, which compromise postural muscle activation and make the hamstrings function more as stabilizers than as main movers. Hamstring tightness manifests because of this basic change in function .

Numerous research has assessed CAI's proximal deficiencies. A few evaluated their strength , and excitability Moreover, alterations in kinematics have been evaluated .

Statement of the problem

This study will try to answer the following question:

Are torso musculature and hamstring flexibility affected in non-athletic patients with unilateral chronic ankle instability? Purpose of the study The purpose of this study is to assess torso musculature in terms of static and dynamic core muscle endurance tests and hamstring flexibility in non-athletic patients with unilateral chronic ankle instability.

Hypotheses

It will be hypothesized that:

1. There is no significant difference in torso musculature in terms of static core muscle endurance between non-athletic healthy participants and non-athletic patients with unilateral chronic ankle instability.
2. There is no significant difference in torso musculature in terms of dynamic core muscle endurance between healthy participants and non-athletic patients with unilateral chronic ankle instability.
3. There is no significant difference in hamstring flexibility between non-athletic healthy participants and non-athletic patients with unilateral chronic ankle instability.

Significance of study Lateral ankle sprain is one of the most common sports injuries, and it has the highest recurrence rate among all lower-extremity musculoskeletal injuries .

chronic ankle instability (CAI) is linked to a lower lifetime quality of life, a lower degree of physical activity, and a higher chance of developing osteoarthritis in the joints .

Ankle sprains occurred 3.29 times per 1000 people annually in US emergency rooms in 2010 . The prevalence of CAI after a sprain is 25% overall, and in otherwise healthy adolescent athletes, it is 20% after an ankle sprain, even though over 15% of cases result in CAI, the public still views ankle sprains as benign injuries .

Hip muscle abnormalities are becoming more common in CAI patients, as described in studies , which might worsen the condition by impairing trunk and pelvic stability and causing the lower body to be malposition as a result .

Reduced lumbopelvic stability may theoretically exacerbate CAI, however this association is still theoretical. Tests that test a person's capacity to maintain hip and trunk alignment can be used to assess lumbar stability. However, no research has up to this point compared to the performance levels of those with and without CAI. Additionally, muscle deficiencies in the hip and trunk can impact lumbopelvic stability. There is, however, a lack of data on the anatomy of the trunk muscles in patients with CAI .

According to previous research, those with CAI experience higher rates of low back pain , delayed trunk muscle activation.

Previous study has investigated the relationship between core stability (CS) and CAI and concluded that, the lack of a clear correlation between trunk endurance and CAI remains unclear; nevertheless, it's possible that the McGill core endurance tests don't accurately assess lumbo-pelvic stability in CAI patients or distinguish between those who have the condition from those who don't. The individuals' sensorimotor systems were not sufficiently challenged by the tests to identify variations between groups. These tests only evaluate the static core endurance.

Therefore, it is crucial to assess torso musculature with CAI for both genders by both static and dynamic core endurance as This facilitates prevention of injury and management of the associated musculoskeletal deficits of CAI.

Previous research evaluating the Arthrogenic Muscle Response of the Hamstrings and Quadriceps with Chronic Ankle Instability produced the conclusion that participants with unilateral CAI had ipsilateral facilitation of the quadriceps and bilateral arthrogenic inhibition of the hamstrings. The motoneuron pool excitability in muscles acting on joints proximal to the ankle seems to be changed in individuals with unilateral CAI. Furthermore, deficiencies in sagittal plane force production were noted at the ankle and the knee, even though the source of instability was at the ankle.

The knee flexor muscles' maximal and submaximal isometric strengths as well as the knee extensor muscles' submaximal strengths are abnormal in people with CAI.

Previous studies assessed hamstring flexibility in ankle sprain or CAI in order to orient the therapist to evaluate the proximal affection that far from the injured site that influencing both preventative and therapeutic approaches to patient care, subsequently completing the evaluation procedures, reduce recurrence rate, restore functional loss and prevent degenerative sequels and concluded that CAI subjects have proximal muscular affection include hamstring tightness which may alter sacroiliac joint stability and subsequently back pain .

Eligibility criteria: Inclusion Criteria:

* Inclusion criteria was based on the standard criteria outlined by the International Ankle Consortium (Gribble et al., 2014).

  1. Their ages range from 20- 35 years old including both genders (male \& female).
  2. Their BMI was 18.5- 30 kg/m2.
  3. A history of the previously injured ankle joint "giving way," and/or recurrent sprain, and/or "feelings of instability."
  4. Report episodes of giving way and sense of instability of the affected ankle
  5. Cumberland Ankle Instability Tool (CAIT) patient scores \< 24.

Exclusion Criteria:

* Subjects were excluded if they have any of the following criteria:( Gribble et al., 2014).

  1. A history of previous surgeries on the musculoskeletal structures (i.e., bones, joint structures, nerves) in either lower extremity.
  2. A history of a fracture in either lower extremity requiring realignment.
  3. Acute injury to musculoskeletal structures of other joints of the lower extremity in the previous 3 months that impacted joint integrity and function (i.e., sprains, fractures), resulting in at least 1 interrupted day of desired physical activity.
  4. Any patient received physical therapy treatment or medical treatment (NSAID)in the last 2weeks Before enrollment in the study.
  5. Any patients suffered from low back pain, lumbar disorder and Sacro iliac joint pain.

Primary outcomes:
measure: 90-90Active knee extension test
timeFrame: 1 session
Secondary outcomes:
measure: Static Core muscles endurance tests
timeFrame: 1 session
Other outcomes:
measure: Dynamic Core muscles endurance test
timeFrame: 1 session
Locations:
city: Cairo
country: Egypt
facility: Cairo university
Study officials:
References: