Clinical trial NCT00722267: European Non-interventional Study in Chronic Obstructive Pulmonary Disease (COPD) Patients
Official title: Patient Perception of Symptom Variability. A Cross-sectional Study of Patients With Severe COPD.
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Chronic Obstructive Pulmonary Disease (COPD)
Keywords: severe COPD
COPD symptoms
variability of symptoms
patient's perception
Lead sponsor: AstraZeneca
Sponsor class: INDUSTRY
First posted: 2008-07-25
Enrollment: 7400
Sex: ALL
Minimum age (years): 45
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: Participating physicians (GPs and Respiratory physicians) will be asked to recruit 4 patients (on average). The first patients presenting for a consultation for any reason, who meet eligibility criteria, and give informed consent, should be enrolled.

Brief summary: This study is investigating how patients with severe stable state COPD perceive the variability of their symptoms throughout the day, the week and the year; the impact of these variations on their daily activities or sleep quality and how they deal with their treatments. For this purpose patients will be asked to answer a questionnaire over the phone


Eligibility criteria: Inclusion Criteria:

* Outpatients with a diagnosis of COPD
* FEV1\<50% and FEV1/FVC\<0.7 according to lung function data in medical records.
* Smoker or ex-smoker \> 10 pack-years
* Informed consent obtained

Exclusion Criteria:

* Ongoing exacerbation of COPD or within the previous 3 months
* Any other significant respiratory disease (including asthma and allergic rhinitis)

Primary outcomes:
measure: Patient's perception of the variability of symptoms due to severe stable state COPD throughout the day, the week and the year
timeFrame: Once
Secondary outcomes:
measure: Impact of symptoms (and variability of symptoms) on the patient's morning & daily living activities and sleep quality.
timeFrame: Once
measure: Describe how patient use their COPD treatment
timeFrame: Once
measure: Factors that may influence the patient's perception of symptom variability
timeFrame: Once
Other outcomes:
Locations:
city: Baden
country: Austria
facility: Research Site
city: Feldbach
country: Austria
facility: Research Site
city: Feldkirch
country: Austria
facility: Research Site
city: Gussing
country: Austria
facility: Research Site
city: Innsbruck
country: Austria
facility: Research Site
city: Landeck
country: Austria
facility: Research Site
city: Linz-Urfahr
country: Austria
facility: Research Site
city: Linz
country: Austria
facility: Research Site
city: Neusiedl am See
country: Austria
facility: Research Site
city: Salzburg
country: Austria
facility: Research Site
city: SchluSSlberg
country: Austria
facility: Research Site
city: Steyr
country: Austria
facility: Research Site
city: Thalheim/Wels
country: Austria
facility: Research Site
city: Wels
country: Austria
facility: Research Site
city: Wien
country: Austria
facility: Research Site
city: Winden
country: Austria
facility: Research Site
city: Wr.Neustadt
country: Austria
facility: Research Site
city: Zwettl
country: Austria
facility: Research Site
city: Aalst
country: Belgium
facility: Research Site
city: Antwerpen
country: Belgium
facility: Research Site
city: Ath
country: Belgium
facility: Research Site
city: Bertogne
country: Belgium
facility: Research Site
city: Boussu
country: Belgium
facility: Research Site
city: Carnieres
country: Belgium
facility: Research Site
city: Chatelet
country: Belgium
facility: Research Site
city: Courcelles
country: Belgium
facility: Research Site
city: Duffel
country: Belgium
facility: Research Site
city: Florennes
country: Belgium
facility: Research Site
city: Gent
country: Belgium
facility: Research Site
city: Geraardsbergen
country: Belgium
facility: Research Site
city: Gosselies
country: Belgium
facility: Research Site
city: Haine-Saint-Paul
country: Belgium
facility: Research Site
city: Houthulst
country: Belgium
facility: Research Site
city: Houtvenne
country: Belgium
facility: Research Site
city: Izegem
country: Belgium
facility: Research Site
city: Kortessem
country: Belgium
facility: Research Site
city: Kraainem
country: Belgium
facility: Research Site
city: Lauwe
country: Belgium
facility: Research Site
city: Liege
country: Belgium
facility: Research Site
city: Lokeren
country: Belgium
facility: Research Site
city: Lommel
country: Belgium
facility: Research Site
city: Micheroux
country: Belgium
facility: Research Site
city: Mons
country: Belgium
facility: Research Site
city: Montzen
country: Belgium
facility: Research Site
city: Olsene
country: Belgium
facility: Research Site
city: Oostende
country: Belgium
facility: Research Site
city: Saive
country: Belgium
facility: Research Site
city: Schaerbeek
country: Belgium
facility: Research Site
city: Sint-Pieters-Woluwe
country: Belgium
facility: Research Site
city: Vielsalm
country: Belgium
facility: Research Site
city: Willebroek
country: Belgium
facility: Research Site
city: Zomergem
country: Belgium
facility: Research Site
city: Aalborg
country: Denmark
facility: Research Site
city: Arhus
country: Denmark
facility: Research Site
city: Brorup
country: Denmark
facility: Research Site
city: Copenhagen S
country: Denmark
facility: Research Site
city: Frederikssund
country: Denmark
facility: Research Site
city: Fredriksberg
country: Denmark
facility: Research Site
city: Grenaa
country: Denmark
facility: Research Site
city: Helsingor
country: Denmark
facility: Research Site
city: Holbaek
country: Denmark
facility: Research Site
city: Holstebro
country: Denmark
facility: Research Site
city: Hvidovre
country: Denmark
facility: Research Site
city: Ikast
country: Denmark
facility: Research Site
city: Jaegerspris
country: Denmark
facility: Research Site
city: Middelfart
country: Denmark
facility: Research Site
city: Oksbol
country: Denmark
facility: Research Site
city: Praesto
country: Denmark
facility: Research Site
city: Roskilde
country: Denmark
facility: Research Site
city: Sindal
country: Denmark
facility: Research Site
city: Skive
country: Denmark
facility: Research Site
city: Svinninge
country: Denmark
facility: Research Site
city: Thisted
country: Denmark
facility: Research Site
city: Hameenlinna
country: Finland
facility: Research Site
city: Helsingin Kaupunki
country: Finland
facility: Research Site
city: Kajaani
country: Finland
facility: Research Site
city: Klaukkala
country: Finland
facility: Research Site
city: Kuopio
country: Finland
facility: Research Site
city: Lahti
country: Finland
facility: Research Site
city: Lappeenranta
country: Finland
facility: Research Site
city: Lohja
country: Finland
facility: Research Site
city: Mikkeli
country: Finland
facility: Research Site
city: Narpio
country: Finland
facility: Research Site
city: Oulu
country: Finland
facility: Research Site
city: Pietarsaari
country: Finland
facility: Research Site
city: Pori
country: Finland
facility: Research Site
city: Pyhajoki
country: Finland
facility: Research Site
city: Sairaalamaki
country: Finland
facility: Research Site
city: Seinajoki
country: Finland
facility: Research Site
city: Tammisaari
country: Finland
facility: Research Site
city: Tampere
country: Finland
facility: Research Site
city: Turku
country: Finland
facility: Research Site
city: Vaaksy
country: Finland
facility: Research Site
city: Agde
country: France
facility: Research Site
city: Aix en Provence
country: France
facility: Research Site
city: Albi
country: France
facility: Research Site
city: Amelie les Bains
country: France
facility: Research Site
city: Angers
country: France
facility: Research Site
city: Annecy
country: France
facility: Research Site
city: Argentan
country: France
facility: Research Site
city: Arles
country: France
facility: Research Site
city: Armentiere
country: France
facility: Research Site
city: Auchy les Mines
country: France
facility: Research Site
city: Augny
country: France
facility: Research Site
city: Aureilhan
country: France
facility: Research Site
city: Avignon
country: France
facility: Research Site
city: Babarthe Sur Leze
country: France
facility: Research Site
city: Bandol
country: France
facility: Research Site
city: Bar le Duc
country: France
facility: Research Site
city: Bayonne
country: France
facility: Research Site
city: Beauvais
country: France
facility: Research Site
city: Belfort
country: France
facility: Research Site
city: Bethune
country: France
facility: Research Site
city: Beziers
country: France
facility: Research Site
city: Bois Guillaume
country: France
facility: Research Site
city: Bordeaux
country: France
facility: Research Site
city: Bourg en Bresse
country: France
facility: Research Site
city: Brest
country: France
facility: Research Site
city: Caen
country: France
facility: Research Site
city: Castelnau le Lez
country: France
facility: Research Site
city: Castelnaudary
country: France
facility: Research Site
city: Cerizay
country: France
facility: Research Site
city: Chalon En Champagne
country: France
facility: Research Site
city: Champs sur Marne
country: France
facility: Research Site
city: Charleville Mezieres
country: France
facility: Research Site
city: Chateauroux
country: France
facility: Research Site
city: Clermont Ferrand
country: France
facility: Research Site
city: Colmar
country: France
facility: Research Site
city: Colomiers
country: France
facility: Research Site
city: Corbeil Essones
country: France
facility: Research Site
city: Creil
country: France
facility: Research Site
city: Creteil
country: France
facility: Research Site
city: Croix
country: France
facility: Research Site
city: Cugnaux
country: France
facility: Research Site
city: Cuise la Motte
country: France
facility: Research Site
city: Denain
country: France
facility: Research Site
city: Desseges
country: France
facility: Research Site
city: Draguignan
country: France
facility: Research Site
city: Echirolles
country: France
facility: Research Site
city: Epernay
country: France
facility: Research Site
city: Epinal
country: France
facility: Research Site
city: Ferolles Attilly
country: France
facility: Research Site
city: Foix
country: France
facility: Research Site
city: Fontainebleau
country: France
facility: Research Site
city: Forbach
country: France
facility: Research Site
city: Giens
country: France
facility: Research Site
city: Gonesse
country: France
facility: Research Site
city: Grasse
country: France
facility: Research Site
city: Graulhet
country: France
facility: Research Site
city: Guingamp
country: France
facility: Research Site
city: Harnes
country: France
facility: Research Site
city: Hyeres
country: France
facility: Research Site
city: Istres
country: France
facility: Research Site
city: Juan les Pins
country: France
facility: Research Site
city: La Baule
country: France
facility: Research Site
city: La Destrousse
country: France
facility: Research Site
city: La Grande Motte
country: France
facility: Research Site
city: La Rochelle
country: France
facility: Research Site
city: Laon
country: France
facility: Research Site
city: Laval
country: France
facility: Research Site
city: Le Brusc
country: France
facility: Research Site
city: Le Chesnay
country: France
facility: Research Site
city: Le Kremlin Bicetre
country: France
facility: Research Site
city: Le Perreux sur Marne
country: France
facility: Research Site
city: Lievin
country: France
facility: Research Site
city: Lille
country: France
facility: Research Site
city: Limoges
country: France
facility: Research Site
city: Lomme
country: France
facility: Research Site
city: Lourdes
country: France
facility: Research Site
city: Luce
country: France
facility: Research Site
city: Lyon
country: France
facility: Research Site
city: Mamande
country: France
facility: Research Site
city: Mandelieu la Napoule
country: France
facility: Research Site
city: Marseille
country: France
facility: Research Site
city: Maury
country: France
facility: Research Site
city: Maxeville
country: France
facility: Research Site
city: Mensignac
country: France
facility: Research Site
city: Molsheim
country: France
facility: Research Site
city: Mont de Marsan
country: France
facility: Research Site
city: Montauban
country: France
facility: Research Site
city: Montbeliard
country: France
facility: Research Site
city: Montfermeil
country: France
facility: Research Site
city: Montigny les Metz
country: France
facility: Research Site
city: Morlaix
country: France
facility: Research Site
city: Nantes
country: France
facility: Research Site
city: Nevers
country: France
facility: Research Site
city: Nice
country: France
facility: Research Site
city: Nimes
country: France
facility: Research Site
city: Niort
country: France
facility: Research Site
city: Nogent sur Marne
country: France
facility: Research Site
city: Obernai
country: France
facility: Research Site
city: Olioules
country: France
facility: Research Site
city: Orsay
country: France
facility: Research Site
city: Paris
country: France
facility: Research Site
city: Perpignan
country: France
facility: Research Site
city: Pertuis
country: France
facility: Research Site
city: Pierre Benite
country: France
facility: Research Site
city: Plouzane
country: France
facility: Research Site
city: Poitiers
country: France
facility: Research Site
city: Pont Eveque
country: France
facility: Research Site
city: Pontallier Sur Saone
country: France
facility: Research Site
city: Ponteil Et Bresis
country: France
facility: Research Site
city: Quimper
country: France
facility: Research Site
city: Quincy Voisins
country: France
facility: Research Site
city: Remiremont
country: France
facility: Research Site
city: Renaze
country: France
facility: Research Site
city: Rennes
country: France
facility: Research Site
city: Roanne
country: France
facility: Research Site
city: Rochefort Cedex
country: France
facility: Research Site
city: Ronchin
country: France
facility: Research Site
city: Rougegoutte
country: France
facility: Research Site
city: Royan
country: France
facility: Research Site
city: Rueil-Malmaison
country: France
facility: Research Site
city: Saint Aubin Des Chateux
country: France
facility: Research Site
city: Saint Feyre
country: France
facility: Research Site
city: Saint-Aubin-les-Elbeuf
country: France
facility: Research Site
city: Saint-Hilaire Agen
country: France
facility: Research Site
city: Saintes
country: France
facility: Research Site
city: Salome
country: France
facility: Research Site
city: Saulnes
country: France
facility: Research Site
city: Segre
country: France
facility: Research Site
city: Selestat
country: France
facility: Research Site
city: Soissons
country: France
facility: Research Site
city: St Amand les Eaux
country: France
facility: Research Site
city: St Cyr sur Loire
country: France
facility: Research Site
city: St Die des Vosges
country: France
facility: Research Site
city: St Etienne
country: France
facility: Research Site
city: St Genis Laval
country: France
facility: Research Site
city: St Jean d'Angely
country: France
facility: Research Site
city: St Jean de Luz
country: France
facility: Research Site
city: St Julien en Genevois
country: France
facility: Research Site
city: St Mamert du Gard
country: France
facility: Research Site
city: St Mandrier sur Mer
country: France
facility: Research Site
city: St Michel
country: France
facility: Research Site
city: St Priest en Jarez
country: France
facility: Research Site
city: St Priest
country: France
facility: Research Site
city: St Quentin
country: France
facility: Research Site
city: St Romain La Motte
country: France
facility: Research Site
city: St Rome de Cernon
country: France
facility: Research Site
city: St Symphorien sur Coise
country: France
facility: Research Site
city: Ste Severe Sur Indre
country: France
facility: Research Site
city: Strasbourg
country: France
facility: Research Site
city: Taden
country: France
facility: Research Site
city: Tarbes
country: France
facility: Research Site
city: Thionville
country: France
facility: Research Site
city: Toulon
country: France
facility: Research Site
city: Toulouse
country: France
facility: Research Site
city: Toul
country: France
facility: Research Site
city: Vabres Labaye
country: France
facility: Research Site
city: Vannes
country: France
facility: Research Site
city: Venerque
country: France
facility: Research Site
city: Venissieux
country: France
facility: Research Site
city: Verdun
country: France
facility: Research Site
city: Villefranche
country: France
facility: Research Site
city: Arnsberg
country: Germany
facility: Research Site
city: Augsburg
country: Germany
facility: Research Site
city: Bad Krozingen
country: Germany
facility: Research Site
city: Bad Sooden-Allendorf
country: Germany
facility: Research Site
city: Bad Vilbel
country: Germany
facility: Research Site
city: Belm
country: Germany
facility: Research Site
city: Bergisch Gladbach
country: Germany
facility: Research Site
city: Berlin
country: Germany
facility: Research Site
city: Bernau
country: Germany
facility: Research Site
city: Bochum
country: Germany
facility: Research Site
city: Bonn
country: Germany
facility: Research Site
city: Borchen
country: Germany
facility: Research Site
city: Borstel
country: Germany
facility: Research Site
city: Brakel
country: Germany
facility: Research Site
city: Burkhardtsdorf
country: Germany
facility: Research Site
city: Castrop-Rauxel
country: Germany
facility: Research Site
city: Delitzsch
country: Germany
facility: Research Site
city: Dieburg
country: Germany
facility: Research Site
city: Dreieich
country: Germany
facility: Research Site
city: Dresden
country: Germany
facility: Research Site
city: Eckental
country: Germany
facility: Research Site
city: Elbingerode
country: Germany
facility: Research Site
city: Eschwege
country: Germany
facility: Research Site
city: Essen
country: Germany
facility: Research Site
city: Frankenberg
country: Germany
facility: Research Site
city: Frankfurt
country: Germany
facility: Research Site
city: Franzburg
country: Germany
facility: Research Site
city: Freiburg
country: Germany
facility: Research Site
city: Freital
country: Germany
facility: Research Site
city: Friedrichsthal
country: Germany
facility: Research Site
city: Furstenfeldbruck
country: Germany
facility: Research Site
city: Furth
country: Germany
facility: Research Site
city: Gelnhausen
country: Germany
facility: Research Site
city: Gelsenkirchen
country: Germany
facility: Research Site
city: Gerolzhofen
country: Germany
facility: Research Site
city: Haan
country: Germany
facility: Research Site
city: Halle
country: Germany
facility: Research Site
city: Haltern
country: Germany
facility: Research Site
city: Hamburg
country: Germany
facility: Research Site
city: Hannover
country: Germany
facility: Research Site
city: Hemmingen
country: Germany
facility: Research Site
city: Ingolstadt
country: Germany
facility: Research Site
city: Kamen
country: Germany
facility: Research Site
city: Kempten
country: Germany
facility: Research Site
city: Kiel
country: Germany
facility: Research Site
city: Koln
country: Germany
facility: Research Site
city: Kothen
country: Germany
facility: Research Site
city: Kronach
country: Germany
facility: Research Site
city: Laichingen
country: Germany
facility: Research Site
city: Leinach
country: Germany
facility: Research Site
city: Leipzig
country: Germany
facility: Research Site
city: Leopoldshohe
country: Germany
facility: Research Site
city: Liebenau
country: Germany
facility: Research Site
city: Ludenscheid
country: Germany
facility: Research Site
city: Magdeburg
country: Germany
facility: Research Site
city: Mammendorf
country: Germany
facility: Research Site
city: Manching
country: Germany
facility: Research Site
city: Marburg
country: Germany
facility: Research Site
city: Marktheidenfeld
country: Germany
facility: Research Site
city: Moers
country: Germany
facility: Research Site
city: Muhlhausen
country: Germany
facility: Research Site
city: Niesky
country: Germany
facility: Research Site
city: Nurnberg
country: Germany
facility: Research Site
city: Oranienburg
country: Germany
facility: Research Site
city: Osnabruck
country: Germany
facility: Research Site
city: Pfronten
country: Germany
facility: Research Site
city: Pleystein
country: Germany
facility: Research Site
city: Pocking
country: Germany
facility: Research Site
city: Potsdam
country: Germany
facility: Research Site
city: Puchheim
country: Germany
facility: Research Site
city: Roth
country: Germany
facility: Research Site
city: Ruhmannsfelden
country: Germany
facility: Research Site
city: Saarbrucken
country: Germany
facility: Research Site
city: Saerbeck
country: Germany
facility: Research Site
city: Schwabach
country: Germany
facility: Research Site
city: Schwedt
country: Germany
facility: Research Site
city: Sebnitz
country: Germany
facility: Research Site
city: Solingen
country: Germany
facility: Research Site
city: Starzach
country: Germany
facility: Research Site
city: Straubing
country: Germany
facility: Research Site
city: Stuttgart
country: Germany
facility: Research Site
city: Teterow
country: Germany
facility: Research Site
city: Welver
country: Germany
facility: Research Site
city: Westerland
country: Germany
facility: Research Site
city: Wettin
country: Germany
facility: Research Site
city: Wiesbaden
country: Germany
facility: Research Site
city: Witten
country: Germany
facility: Research Site
city: Zerbst
country: Germany
facility: Research Site
city: Athens
country: Greece
facility: Research Site
city: Chalkida
country: Greece
facility: Research Site
city: Chania
country: Greece
facility: Research Site
city: Drapetsona
country: Greece
facility: Research Site
city: Florina
country: Greece
facility: Research Site
city: Heraklio
country: Greece
facility: Research Site
city: Ilioupoli
country: Greece
facility: Research Site
city: Ithaki
country: Greece
facility: Research Site
city: Kalamaria
country: Greece
facility: Research Site
city: Kifissia
country: Greece
facility: Research Site
city: Koropi
country: Greece
facility: Research Site
city: Lamia
country: Greece
facility: Research Site
city: Messini
country: Greece
facility: Research Site
city: N.Santa
country: Greece
facility: Research Site
city: Patra
country: Greece
facility: Research Site
city: Platamonas
country: Greece
facility: Research Site
city: Preveza
country: Greece
facility: Research Site
city: Serres
country: Greece
facility: Research Site
city: Thessaloniki
country: Greece
facility: Research Site
city: Veroia
country: Greece
facility: Research Site
city: Cavan
country: Ireland
facility: Research Site
city: Dublin
country: Ireland
facility: Research Site
city: Enniscorthy
country: Ireland
facility: Research Site
city: Gorey
country: Ireland
facility: Research Site
city: Letterkenny
country: Ireland
facility: Research Site
city: Mullingar
country: Ireland
facility: Research Site
city: Turloughmore
country: Ireland
facility: Research Site
city: Waterford
country: Ireland
facility: Research Site
city: Alife
country: Italy
facility: Research Site
city: Avezzano
country: Italy
facility: Research Site
city: Badolato
country: Italy
facility: Research Site
city: Balsorano
country: Italy
facility: Research Site
city: Carsoli
country: Italy
facility: Research Site
city: Casa Giove
country: Italy
facility: Research Site
city: Caserta
country: Italy
facility: Research Site
city: Ceparana
country: Italy
facility: Research Site
city: Copertino
country: Italy
facility: Research Site
city: Cutrofiano
country: Italy
facility: Research Site
city: Eboli
country: Italy
facility: Research Site
city: Grosseto
country: Italy
facility: Research Site
city: La Spezia
country: Italy
facility: Research Site
city: Macerata Campania
country: Italy
facility: Research Site
city: Montiano
country: Italy
facility: Research Site
city: Napoli
country: Italy
facility: Research Site
city: Orbetello
country: Italy
facility: Research Site
city: Ortonovo
country: Italy
facility: Research Site
city: Paganico
country: Italy
facility: Research Site
city: Palermo
country: Italy
facility: Research Site
city: Pellezzano
country: Italy
facility: Research Site
city: Pontecagnano
country: Italy
facility: Research Site
city: Rispescia
country: Italy
facility: Research Site
city: S.Maria Di Cantanzzaro
country: Italy
facility: Research Site
city: Salerno
country: Italy
facility: Research Site
city: San Felice a Cancello
country: Italy
facility: Research Site
city: San Nicola La Strada
country: Italy
facility: Research Site
city: San Pietro in Lama
country: Italy
facility: Research Site
city: Srubo
country: Italy
facility: Research Site
city: Trasacco
country: Italy
facility: Research Site
city: Veglie
country: Italy
facility: Research Site
city: Almere
country: Netherlands
facility: Research Site
city: Alphen Aan Den Rijn
country: Netherlands
facility: Research Site
city: Amsterdam
country: Netherlands
facility: Research Site
city: Andijk
country: Netherlands
facility: Research Site
city: Arnhem
country: Netherlands
facility: Research Site
city: Delfzijl
country: Netherlands
facility: Research Site
city: Den Helder
country: Netherlands
facility: Research Site
city: Drachten
country: Netherlands
facility: Research Site
city: Enschede
country: Netherlands
facility: Research Site
city: Gouda
country: Netherlands
facility: Research Site
city: Groningen
country: Netherlands
facility: Research Site
city: Heemstede
country: Netherlands
facility: Research Site
city: Heerlen
country: Netherlands
facility: Research Site
city: Hilversum
country: Netherlands
facility: Research Site
city: Hoogwoud
country: Netherlands
facility: Research Site
city: Landgraaf
country: Netherlands
facility: Research Site
city: Leiden
country: Netherlands
facility: Research Site
city: Meppel
country: Netherlands
facility: Research Site
city: Onstwedde
country: Netherlands
facility: Research Site
city: Oude Pekela
country: Netherlands
facility: Research Site
city: Roermond
country: Netherlands
facility: Research Site
city: Rotterdam
country: Netherlands
facility: Research Site
city: S-Gravenhage
country: Netherlands
facility: Research Site
city: S-Hertogenbosch
country: Netherlands
facility: Research Site
city: Sint Philipsland
country: Netherlands
facility: Research Site
city: Sneek
country: Netherlands
facility: Research Site
city: Tilburg
country: Netherlands
facility: Research Site
city: Utrecht
country: Netherlands
facility: Research Site
city: Zutphen
country: Netherlands
facility: Research Site
city: Alesund
country: Norway
facility: Research Site
city: Brevik
country: Norway
facility: Research Site
city: Hakadal
country: Norway
facility: Research Site
city: Molde
country: Norway
facility: Research Site
city: Oslo
country: Norway
facility: Research Site
city: Trondheim
country: Norway
facility: Research Site
city: Coimbra
country: Portugal
facility: Research Site
city: Lisboa
country: Portugal
facility: Research Site
city: Melgaco
country: Portugal
facility: Research Site
city: Odivelas
country: Portugal
facility: Research Site
city: Santarém
country: Portugal
facility: Research Site
city: Torres Vedras
country: Portugal
facility: Research Site
city: A Coruna
country: Spain
facility: Research Site
city: Alamagro
country: Spain
facility: Research Site
city: Alcal De Henares
country: Spain
facility: Research Site
city: Alcoy
country: Spain
facility: Research Site
city: Alicante
country: Spain
facility: Research Site
city: Andujar
country: Spain
facility: Research Site
city: Arcos De La Fortera
country: Spain
facility: Research Site
city: As Pontes De Garcia Rodriguez
country: Spain
facility: Research Site
city: Avila
country: Spain
facility: Research Site
city: Aviles
country: Spain
facility: Research Site
city: Badalona
country: Spain
facility: Research Site
city: Baracaldo
country: Spain
facility: Research Site
city: Barcelona
country: Spain
facility: Research Site
city: Bellaterra
country: Spain
facility: Research Site
city: Bilbao
country: Spain
facility: Research Site
city: Boqueixon (Pontella)
country: Spain
facility: Research Site
city: Brean Alta
country: Spain
facility: Research Site
city: Burela
country: Spain
facility: Research Site
city: Burgos
country: Spain
facility: Research Site
city: Burguillos
country: Spain
facility: Research Site
city: Carvaca De La Cruz
country: Spain
facility: Research Site
city: Castellon de la Plana
country: Spain
facility: Research Site
city: Cervera
country: Spain
facility: Research Site
city: Cesuras
country: Spain
facility: Research Site
city: Cuenca
country: Spain
facility: Research Site
city: El Vendrell
country: Spain
facility: Research Site
city: Ferrol
country: Spain
facility: Research Site
city: Fuenlabrada
country: Spain
facility: Research Site
city: Girona
country: Spain
facility: Research Site
city: Granollers
country: Spain
facility: Research Site
city: Guadalajara
country: Spain
facility: Research Site
city: Huelva
country: Spain
facility: Research Site
city: Jaen
country: Spain
facility: Research Site
city: Joiosa
country: Spain
facility: Research Site
city: La Almunia de Dona Godina
country: Spain
facility: Research Site
city: Laredo
country: Spain
facility: Research Site
city: Las Palmas De Gran Canaria
country: Spain
facility: Research Site
city: Leganes
country: Spain
facility: Research Site
city: Llobregat
country: Spain
facility: Research Site
city: Logrono
country: Spain
facility: Research Site
city: Lora Del Rio
country: Spain
facility: Research Site
city: Lugo
country: Spain
facility: Research Site
city: Madrid
country: Spain
facility: Research Site
city: Manacor
country: Spain
facility: Research Site
city: Melilla
country: Spain
facility: Research Site
city: Mieres
country: Spain
facility: Research Site
city: Montilla
country: Spain
facility: Research Site
city: Murcia
country: Spain
facility: Research Site
city: Outes
country: Spain
facility: Research Site
city: Oviedo
country: Spain
facility: Research Site
city: Palma De Mallorca
country: Spain
facility: Research Site
city: Pamplona
country: Spain
facility: Research Site
city: Ponferrada
country: Spain
facility: Research Site
city: Porreres
country: Spain
facility: Research Site
city: Portugalete
country: Spain
facility: Research Site
city: Pozoblanco
country: Spain
facility: Research Site
city: Quart de Poblet
country: Spain
facility: Research Site
city: Quintanar Del Rey
country: Spain
facility: Research Site
city: Ronda
country: Spain
facility: Research Site
city: Sabadell
country: Spain
facility: Research Site
city: Sagunto
country: Spain
facility: Research Site
city: Salamanca
country: Spain
facility: Research Site
city: Salt
country: Spain
facility: Research Site
city: San Sebastian
country: Spain
facility: Research Site
city: Sant Antoni de Portmany
country: Spain
facility: Research Site
city: Sant Boi De Llobregat
country: Spain
facility: Research Site
city: Sant Pere De Ribes
country: Spain
facility: Research Site
city: Sant Vicent Del Raspeig
country: Spain
facility: Research Site
city: santa Coloma de Gramenet
country: Spain
facility: Research Site
city: Santa Coloma De Queralt
country: Spain
facility: Research Site
city: Santiago De Compostella
country: Spain
facility: Research Site
city: Santurtzi
country: Spain
facility: Research Site
city: Teruel
country: Spain
facility: Research Site
city: Toledo
country: Spain
facility: Research Site
city: Torrebonica
country: Spain
facility: Research Site
city: Torrelavega
country: Spain
facility: Research Site
city: Valdepenas
country: Spain
facility: Research Site
city: Valencia
country: Spain
facility: Research Site
city: Valladolid
country: Spain
facility: Research Site
city: Vigo
country: Spain
facility: Research Site
city: Viladecans
country: Spain
facility: Research Site
city: Xativa
country: Spain
facility: Research Site
city: Angered
country: Sweden
facility: Research Site
city: Atvidaberg
country: Sweden
facility: Research Site
city: Bjarred
country: Sweden
facility: Research Site
city: Borlange
country: Sweden
facility: Research Site
city: Danderyd
country: Sweden
facility: Research Site
city: Falun
country: Sweden
facility: Research Site
city: Forserum
country: Sweden
facility: Research Site
city: Fredriksberg
country: Sweden
facility: Research Site
city: Gavle
country: Sweden
facility: Research Site
city: Goteborg
country: Sweden
facility: Research Site
city: Hollviken
country: Sweden
facility: Research Site
city: Hunnebostrand
country: Sweden
facility: Research Site
city: Kalarne
country: Sweden
facility: Research Site
city: Kinna
country: Sweden
facility: Research Site
city: Kungsbacka
country: Sweden
facility: Research Site
city: Malmo
country: Sweden
facility: Research Site
city: Norrkoping
country: Sweden
facility: Research Site
city: Ostersund
country: Sweden
facility: Research Site
city: Stockholm
country: Sweden
facility: Research Site
city: Sundsvall
country: Sweden
facility: Research Site
city: Uppsala
country: Sweden
facility: Research Site
city: Varnamo
country: Sweden
facility: Research Site
city: Bern
country: Switzerland
facility: Research Site
city: Davos Wolfgang
country: Switzerland
facility: Research Site
city: Herisau
country: Switzerland
facility: Research Site
city: Lausanne
country: Switzerland
facility: Research Site
city: Martigny
country: Switzerland
facility: Research Site
city: Samedan
country: Switzerland
facility: Research Site
city: Spiez
country: Switzerland
facility: Research Site
city: Zurich
country: Switzerland
facility: Research Site
city: Adana
country: Turkey
facility: Research Site
city: Akyokus-Konya
country: Turkey
facility: Research Site
city: Anamur/mersin
country: Turkey
facility: Research Site
city: Ankara
country: Turkey
facility: Research Site
city: Aydin
country: Turkey
facility: Research Site
city: Denizli
country: Turkey
facility: Research Site
city: Erzincan
country: Turkey
facility: Research Site
city: Eskisehir
country: Turkey
facility: Research Site
city: Hatay
country: Turkey
facility: Research Site
city: Istanbul
country: Turkey
facility: Research Site
city: Izmir
country: Turkey
facility: Research Site
city: K.Maras
country: Turkey
facility: Research Site
city: Konya
country: Turkey
facility: Research Site
city: Malatya
country: Turkey
facility: Research Site
city: Mezitli-Mersin
country: Turkey
facility: Research Site
city: Osmaniye
country: Turkey
facility: Research Site
city: Sakarya
country: Turkey
facility: Research Site
city: Sanliurfa
country: Turkey
facility: Research Site
city: umraniye-Istanbul
country: Turkey
facility: Research Site
city: Yenisehir
country: Turkey
facility: Research Site
city: Yozgat
country: Turkey
facility: Research Site
city: Zonguldak
country: Turkey
facility: Research Site
city: Ashwell
country: United Kingdom
facility: Research Site
city: Atherstone
country: United Kingdom
facility: Research Site
city: Barry
country: United Kingdom
facility: Research Site
city: Birmingham
country: United Kingdom
facility: Research Site
city: Blackburn
country: United Kingdom
facility: Research Site
city: Blackpool
country: United Kingdom
facility: Research Site
city: Bradford-On-Avon
country: United Kingdom
facility: Research Site
city: Cardiff
country: United Kingdom
facility: Research Site
city: Chertsey
country: United Kingdom
facility: Research Site
city: Chesterfield
country: United Kingdom
facility: Research Site
city: Chippenham
country: United Kingdom
facility: Research Site
city: Cookstown
country: United Kingdom
facility: Research Site
city: Corsham
country: United Kingdom
facility: Research Site
city: Coventry
country: United Kingdom
facility: Research Site
city: Doncaster
country: United Kingdom
facility: Research Site
city: Fife
country: United Kingdom
facility: Research Site
city: High Valleyfield
country: United Kingdom
facility: Research Site
city: Maidenhead
country: United Kingdom
facility: Research Site
city: Nottingham
country: United Kingdom
facility: Research Site
city: Peterborough
country: United Kingdom
facility: Research Site
city: Plymouth
country: United Kingdom
facility: Research Site
city: Ruislip
country: United Kingdom
facility: Research Site
city: Sandy
country: United Kingdom
facility: Research Site
city: Southampton
country: United Kingdom
facility: Research Site
city: Sunbury on Thames
country: United Kingdom
facility: Research Site
city: Thornton Heath
country: United Kingdom
facility: Research Site
city: Trowbridge
country: United Kingdom
facility: Research Site
city: Warminster
country: United Kingdom
facility: Research Site
city: Wells next the Sea
country: United Kingdom
facility: Research Site
city: Westbury
country: United Kingdom
facility: Research Site
Study officials:
References:
citation: Kessler R, Partridge MR, Miravitlles M, Cazzola M, Vogelmeier C, Leynaud D, Ostinelli J. Symptom variability in patients with severe COPD: a pan-European cross-sectional study. Eur Respir J. 2011 Feb;37(2):264-72. doi: 10.1183/09031936.00051110. Epub 2010 Nov 29.