Clinical trial NCT05759091: Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia
Official title: The Effect of Applying Cognitive Defusion Techniques on Mindful Awareness, Cognitive Fusion and Believability of Delusions Among Clients With Schizophrenia: A Randomized Control Trial
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Schizophrenia; Psychosis
Nurse's Role
Delusions
Keywords: Believability of Delusions
Cognitive Defusion techniques
Cognitive Fusion
Mindful Awareness
Schizophrenia
Lead sponsor: Alexandria University
Sponsor class: OTHER
First posted: 2023-03-08
Enrollment: 70
Sex: MALE
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: Schizophrenia causes hallucinations, delusions, and disorganized thinking, resulting in decreased functioning and lifelong therapy.Delusion believability is the degree of belief in the truth of one's subjective experiences as representations of reality. It was unpleasant, typically accompanied by a suspicious, strange tension. Delusional belief is seen as a means of resolving tension and conflict in cognition and experience. Previous studies have shown that cognitive defusion strategies help people become more aware of their surroundings, accept their thoughts and feelings, and become more psychologically adjustable. defusion is crucial in reducing medication-resistant psychotic symptoms such delusions in schizophrenia patients. Therefore, this study aimed to investigate the effects of cognitive defusion techniques on psychological flexibility, mindful awareness, cognitive fusion, and believability of delusions among clients with schizophrenia.

Research Hypothesizes

* Clients who participated in cognitive defusion techniques had more psychological flexibility and mindful awareness than the control group.
* Clients who participated in cognitive defusion techniques had less cognitive fusion and delusional believability than the control group.


Eligibility criteria: Inclusion Criteria:

* Male clients diagnosed with schizophrenia according to the DSM-V
* Diagnosed with schizophrenia With no comorbidity.
* Able to communicate coherently and relevantly.
* Able to read and write.
* Willing to participate in the study
* Duration of illness not exceeding 10 years.

Exclusion Criteria:

• Any client in an acute phase or have any neurological disorder that may affect cognitive function were excluded from a study.

Primary outcomes:
measure: The Acceptance and Action Questionnaire-II (AAQII)
timeFrame: up to 14 weeks
measure: The Cognitive Fusion Questionnaire-7 (CFQ-7)
timeFrame: up to 14 weeks
measure: Southampton Mindfulness Questionnaire (SMQ)
timeFrame: up to 14 weeks
measure: Psychotic Symptom Rating Scales (PSYRATS-D)
timeFrame: up to 14 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Alexandria
country: Egypt
facility: Faculty of Nursing
Study officials:
affiliation: Faculty of nursing, Alexandria University, Egypt
name: Ayman Mohamed El-Ashry, PHD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Bach P, Hayes SC. The use of acceptance and commitment therapy to prevent the rehospitalization of psychotic patients: a randomized controlled trial. J Consult Clin Psychol. 2002 Oct;70(5):1129-39. doi: 10.1037//0022-006x.70.5.1129.
citation: Hayes SC. Acceptance and Commitment Therapy, Relational Frame Theory, and the Third Wave of Behavioral and Cognitive Therapies - Republished Article. Behav Ther. 2016 Nov;47(6):869-885. doi: 10.1016/j.beth.2016.11.006. Epub 2016 Nov 10.
citation: Boge K, Pollex F, Bergmann N, Hahne I, Zierhut MM, Mavituna S, Thomas N, Hahn E. Mindfulness, cognitive fusion, and self-compassion in patients with schizophrenia spectrum disorders-A cross-sectional study. Front Psychiatry. 2022 Aug 2;13:959467. doi: 10.3389/fpsyt.2022.959467. eCollection 2022.