Clinical trial NCT05058794: Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.
Official title: Effects of Blood Flow Restriction Training vs Traditional Exercise in Patients With Knee Osteoarthritis.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Osteoarthritis, Knee
Hypertrophy
Keywords: Osteoarthritis
Blood Flow Restriction
Quadriceps
Resistance Training
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2021-09-28
Enrollment: 42
Sex: ALL
Minimum age (years): 40
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The main objective of the study is to compare the effects of Blood flow Restriction training vs. traditional exercises on knee pain , knee functional disability and on quadriceps strength in patient with knee osteoarthritis.

Detailed description: Osteoarthritis is a degenerative disease affecting the most commonly weight bearing joint.The common form of arthritis is osteoarthritis (OA) causing structural changes in the joint. Age is a common factor affecting the strength and muscle mass.Worldwide there is a drastic increase of osteoarthritis in the older population. In the past 20 years the prevalence of knee pain increased and reached up to 50% in the older population. The most common OA affecting lower extremity is in the knee Joint.Majority of the people affected by knee OA are the older population. Knee Joints being the most weight bearing joint affected in OA causing pain , limiting function and mobility.Mobility and function may be affected in osteoarthritic population usually experience pain and stiffness.

The main objective of this study is to compare the Effects of blood Flow restriction training vs conventional treatment exercises on knee pain, functional disability and quadriceps strengthening.

The main purpose of this study is to improve the muscular strength of lower limbs which are being affected in a disease osteoarthritis in the adult population.

Eligibility criteria: Inclusion Criteria:

* Pain : Subjects having unilateral or bilateral pain
* Pain type : subjects having chronic pain
* Includes diagnosed cases of knee osteoarthritis
* grades 2-3 according to the Kellgren and Lawrence method of grading
* Includes knee osteoarthritis patients with lateral tracking of patella which will assessed through Q angle test

Exclusion Criteria:

* Any other orthopaedic or neurological condition of hip and knee
* Sign and symptoms of lower motor neuron disease
* Current use of medication
* Radiculopathy
* Fracture
* Malignancy
* Thromboembolism
* Decreased range of motion

Primary outcomes:
measure: Muscle strength
timeFrame: 6 weeks
measure: Thigh Girth
timeFrame: 6 weeks
measure: Numeric Pain Rating Scale ( NPRS)
timeFrame: 6 weeks
measure: Q angle Measurement
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Gulberg Medical Complex
state: Federal
city: Islamabad
country: Pakistan
facility: Medcity International Hospital
state: Federal
Study officials:
affiliation: Riphah International University
name: Saad Rauf, Master
role: PRINCIPAL_INVESTIGATOR
References: