Clinical trial NCT06147726: Upper Extremity Rehabilitation With Virtual Reality in Parkinson's Disease Patients
Official title: Effectiveness of Virtual Reality Supported Upper Extremity Position Matching Exercises in Parkinson's Disease Patients
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Parkinson Disease
Virtual Reality
Neurological Rehabilitation
Upper Extremity Dysfunction
Lead sponsor: Abant Izzet Baysal University
Sponsor class: OTHER
Collaborators: name: Abant Izzet Baysal University
First posted: 2023-11-28
Enrollment: 24
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: 2 groups, conventional physiotherapy to the control group
Primary purpose: TREATMENT

Brief summary: Upper extremities are the first part of the body to be affected by Parkinson's disease. Although studies have shown that virtual reality-assisted rehabilitation methods are effective on gait and balance, studies on their use for upper extremity rehabilitation are limited. For this reason, the aim of the project is to examine whether virtual reality supported upper extremity position matching exercises, which will be specially prepared according to joint ranges of motion, will provide functional improvement in the upper extremities of individuals with Parkinson's disease.

Detailed description: Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor disorders. Difficulties in using the upper limbs caused by these motor impairments are common with the disease. Upper limb motor impairments in PD include slowness of movement, difficulties in performing sequential tasks and limitations in upper limb function. Studies show that the upper extremities are usually the most affected body region in the early stages of PD. Despite this, the number of rehabilitation methods that can be used for upper extremity rehabilitation is limited. Impairments in upper extremity motor function constitute a leading problem in the lives of individuals with PD by affecting their ability to perform activities of daily living. Virtual reality applications stand out as an innovative approach in neurorehabilitation. Previous studies have reported positive effects of virtual reality on gait function and balance in PD. However, the number of studies designed with virtual reality for the upper limb is limited. Therefore, this project aims to fill the gap in the literature by examining the effectiveness of virtual reality-based rehabilitation in PD with a particular focus on upper extremity motor function and proprioception.

Eligibility criteria: Inclusion Criteria:

* Accepting to participate in the research
* Being diagnosed with Parkinson's Disease by a neurologist
* Continuing anti-parkinsonian medication
* Hoehn-Yahr (H-Y) stage 3 and below
* Ability to walk independently
* To have full range of motion in shoulder abduction and elbow extension movements

Exclusion Criteria:

* Presence of additional neurological diseases other than Parkinson's Disease
* Scores below 21 on the Montreal Cognitive Assessment Scale
* Change in medication dosage in the last 1 month
* Severe visual impairment or complete hearing impairment in both ears
* Having a rheumatologic, musculoskeletal, etc. disease that may affect upper extremity functions
* The occurrence of severe tremors or dyskinesias due to the end of the drug dose
* Failing the Titmus butterfly test

Primary outcomes:
measure: Action Research Arm Test
timeFrame: through study completion, an average of 1 year
measure: Proprioception Assessment
timeFrame: through study completion, an average of 1 year
Secondary outcomes:
measure: Unified Parkinson's Disease Rating Scale
timeFrame: through study completion, an average of 1 year
measure: Disabilities of the Arm, Shoulder, and Hand Questionnaire
timeFrame: through study completion, an average of 1 year
measure: Parkinson's Disease Questionnaire (PDQ-8)
timeFrame: through study completion, an average of 1 year
measure: Global rating of change score-GRC
timeFrame: average 1 year after the completion of the study
Other outcomes:
Locations:
city: Bolu
country: Turkey
facility: Faculty of Health Sciences Bolu Abant Izzet Baysal University
state: Merkez
Study officials:
affiliation: Abant Izzet Baysal University
name: Ramazan Kurul, Ph.D
role: PRINCIPAL_INVESTIGATOR
References: