Clinical trial NCT01163279: Maintaining Autonomy as we Age. Strategy Training for Age-related Executive Dysfunction.
Official title: Maintaining Autonomy as we Age: Investigating the Application of a Strategy Training Approach for Ameliorating the Effects of Age-related Executive Dysfunction - Part II
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Aging
Keywords: Age-related changes
Lead sponsor: Baycrest
Sponsor class: OTHER
First posted: 2010-07-15
Enrollment: 19
Sex: ALL
Minimum age (years): 65
Maximum age (years): 90
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: OTHER

Brief summary: Healthy older adults with self-reported cognitive difficulties who receive strategy training will demonstrate greater performance benefits on measures of real-world activities, relative to those receiving a control intervention, immediately post treatment and at follow-up.


Eligibility criteria: Inclusion Criteria:

* All participants must score within 1.5 standard deviation (SD) of age and education-corrected normative data for the Montreal Cognitive Assessment and on a battery of neuropsychological tests of attention, memory and executive function (which will insure that participants are unlikely to meet the criteria for Mild Cognitive Impairment (MCI)).
* No clinically relevant depression (scores ≤22) on the Center for Epidemiologic Studies Depression Scale (CES-D)
* Fluent in written and spoken English
* Self-reported complains about cognitive function

Exclusion Criteria:

* Recent bereavement (within last 6 months)
* History of neurological disease
* Psychiatric illness requiring hospitalization and/or history or current substance abuse

Primary outcomes:
measure: Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM)
timeFrame: Immediately post intervention (2 months) and 3 months later
Secondary outcomes:
measure: General Self Efficacy Scale (GSE)
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: Stanford Patient Education Research Center- General Health Subscale
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: Stanford Patient Education Research Center- Health Distress Subscale
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: Stanford Patient Education Research Center- Physical Activity Subscale
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: Stanford Patient Education Research Center- Communication With Physicians Subscale
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: Stanford Patient Education Research Center- Visits to Physician and Emergency Department in the Past Six Months Subscale
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: Delis Kaplan Executive Function System (DKEFS) Tower Test- Mean First-Move Time
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: DKEFS Tower Test- Achievement Score
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: DKEFS Word Fluency
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
measure: DKEFS Trail Making- Condition 4: Number-letter Switching
timeFrame: Baseline, Immediately post intervention (2 months) and 3 months later
Other outcomes:
Locations:
city: Toronto
country: Canada
facility: Baycrest
state: Ontario
Study officials:
affiliation: Rotman Research Institute, Baycrest
name: Deirdre Dawson, PhD
role: PRINCIPAL_INVESTIGATOR
References: