Clinical trial NCT05461391: The Effects of COVID-19 Infection on Respiratory Muscle Strength and Core Stabilization
Official title: The Effects of COVID-19 Infection on Respiratory Muscle Strength and Core Stabilization in Healthy Individuals Who Exercise Regularly
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: COVID-19
Pandemic, COVID-19
Corona Virus Infection
Keywords: covid-19
coronavirus
respiratory physiotherapy
core stabilization
Lead sponsor: Yeditepe University
Sponsor class: OTHER
Collaborators: name: Bezmialem Vakif University
First posted: 2022-07-18
Enrollment: 50
Sex: ALL
Minimum age (years): 18
Maximum age (years): 50
Standard ages: ADULT
Accepts healthy volunteers: yes
Observational model: CASE_CONTROL
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Data will be evaluated in healthy adult volunteers who agreed to participate in the clinical study at Bezmialem Vakıf University Dragos Hospital between February and April.

Brief summary: World Health Organization (WHO) Novel-19 Corrosion Disease (COVID) in 2019 without being used by a pathway caused by the SARS-CoV-2 virus. After the acute period in COVID-19 patients, muscle weakness may continue in breathing, weakness, and training. The effects on core stabilization, pulmonary functions, respiratory muscle strength, physical activity scores and quality of life in healthy adults who do not have COVID-19 who do regular exercise may be higher than in healthy adults who do regular exercise with COVID-19.

Detailed description: The type of our study was planned as Case-Control. 50 exercises will be included in our study. The first COVID-19 (n= 25) is healthy, and the second group will come from the successful group without COVID-19 (n=25). Between February and April, a student will accept participating in the clinic at Bezmialem Foundation University. After being informed about it, the attached form will be signed. In addition, participants will be asked to fill in our attached document, including demographic and clinical studies, in a face-to-face interview. All body exercises, breathing muscle test, six-minute walking test, McGill core endurance test, short-form test, and quality of life test were planned in our two groups. The results of these tests will be evaluated by testing and checking.

Eligibility criteria: Inclusion Criteria:

1. To be between the ages of 18-50,
2. Volunteering to participate in the research,
3. Those who have done aerobic exercise at least three days a week in the last three months

Exclusion Criteria:

1. Neurological deficits in the upper or lower extremities,
2. Fractures or orthopedic problems in the upper or lower extremities,
3. Cardiovascular diseases that prevent rehabilitation,
4. Systematic rheumatic disease (rheumatoid arthritis, ankylosing spondylitis),
5. History of surgery in the last three months,
6. Patients with spine problems,
7. Smokers,
8. Patients with chronic respiratory problems.

Primary outcomes:
measure: Pulmonary Function Test
timeFrame: 8 weeks
measure: Respiratory Muscle Strength
timeFrame: 8 weeks
measure: Six Minute Walk Test (6MWT)
timeFrame: 8 weeks
measure: McGill Core Endurance Test
timeFrame: 8 weeks
Secondary outcomes:
measure: International Physical Activity Questionnaire - Short Form (IPAQ-SF)
timeFrame: 8 weeks
measure: Quality of Life Scale (SF36)
timeFrame: 8 weeks
measure: Dyspnea Scale
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Bezmialem Vakif University Dragos Hospital
state: Maltepe
Study officials:
affiliation: Bezmialem Vakif University Dragos Hospital
name: ildeniz yalnız
role: STUDY_DIRECTOR
affiliation: Yeditepe University
name: elif develi
role: PRINCIPAL_INVESTIGATOR
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citation: Develi E, Subasi F, Aslan GK, Bingol Z. The effects of core stabilization training on dynamic balance and pulmonary parameters in patients with asthma. J Back Musculoskelet Rehabil. 2021;34(4):639-648. doi: 10.3233/BMR-191803.