Clinical trial NCT02300272: Health Behaviors and Time-of-Day: Older Adult Cognitive Function
Official title: Modifiable Health Behaviors Associated With Time-of-Day Differences in Older Adults' Practice-Related Learning
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Alteration of Cognitive Function
Ageing
Keywords: Practice-related learning
Sleep
Pain
Circadian Rhythm
Older Adults
Lead sponsor: University of Florida
Sponsor class: OTHER
First posted: 2014-11-24
Enrollment: 88
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Typically, healthy older adults

Brief summary: This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device. The study period will last 2 weeks. The objectives of the study are to examine the impact of sleep, pain, and circadian rhythm on practice-related learning in older adults at their preferred versus nonpreferred times of day.

Detailed description: Participants will be asked to review the informed consent and consent to the study prior to any study procedure.

There are four stages to this study: 1. a telephone interview, 2. an in-person interview and completion of questionnaires, 3. an in-home single night sleep recording, and 4. two weeks of computerized cognitive testing, subjective sleep and pain recordings, and wearing a Actiwatch.

During the telephone interview, participants will be asked question about their age, sleep, pain, and medical/mental health history. At a second visit, participants will complete a more in-depth interview of their physical health, mental health, sleep, and pain history. They will complete a brief test of their cognitive functioning. They will also complete 4 questionnaires about their time of day preference and mood. At the third visit, participants will visit the University of Florida to be connected to a machine which will monitor their sleep. Participants will return home to sleep while still connected to the machine and will return the machine to the University of Florida the next day. Participants will complete brief computerized daily questionnaires of sleep and pain and cognitive testing in the morning and evening, and and wear an actigraph (wristwatch-like device) that measures arm movements and ambient light for two weeks.

Eligibility criteria: Inclusion Criteria:

* Age of 65 years and older
* Able to read and speak English
* Completion of Morningness-Eveningness Questionnaire

Exclusion Criteria:

* Significant medical or neurological disorder
* Major psychopathology
* Pain disorder other than fibromyalgia or osteoarthritis
* Sleep disorder other than insomnia
* Cognitive impairment
* Psychotropic or other medications known to alter sleep
* Unable to provide informed consent

Primary outcomes:
measure: Cognition as assessed by computerized neuropsychological testing
timeFrame: Morning and evening completion for 14 days
Secondary outcomes:
Other outcomes:
Locations:
city: Gainesville
country: United States
facility: University of Florida
state: Florida
Study officials:
affiliation: University of Florida
name: Michael E Robinson, Ph.D.
role: PRINCIPAL_INVESTIGATOR
References: