Clinical trial NCT06463301: Effects of Treadmill Training on Motor Function, Balance, and Spasticity Reduction in Children With Cerebral Palsy
Official title: Effects of Treadmill Training on Motor Function, Balance, and Spasticity Reduction in Children With Cerebral Palsy
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Cerebral Palsy
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2024-06-17
Enrollment: 36
Sex: ALL
Minimum age (years): 4
Maximum age (years): 12
Standard ages: CHILD
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: SUPPORTIVE_CARE

Brief summary: This study investigates the impact of treadmill training on motor function, balance, and spasticity reduction in children with cerebral palsy (CP). The study synthesizes existing research to provide insights into the effectiveness of treadmill training as an intervention for improving these key outcomes in children with Cerebral palsy

Detailed description: Cerebral palsy is a neurodevelopmental disorder characterized by impaired movement and posture due to non-progressive brain damage occurring before, during, or shortly after birth.this systematic review and meta-analysis comprehensively examines the effects of treadmill training on motor function, balance, and spasticity reduction in children diagnosed with cerebral palsy (CP).

The review includes studies published in peer-reviewed journals, databases, and relevant conference proceedings. Inclusion criteria encompass randomized controlled trials, quasi-experimental studies, and cohort studies evaluating treadmill training interventions in children aged 2-18 years with CP. Studies utilizing various treadmill training protocols, such as body-weight-supported treadmill training, overground treadmill training, or virtual reality-assisted treadmill training, are considered.

The primary outcomes assessed include changes in motor function, as measured by standardized assessment tools like the Gross Motor Function Measure (GMFM) or the Movement Assessment Battery for Children (MABC). Additionally, balance improvements are evaluated using validated balance assessment scales, while spasticity reduction is measured through clinical assessments, such as the Modified Ashworth Scale (MAS) or the Tardieu Scale.

The review aims to provide evidence-based insights into the efficacy of treadmill training as a rehabilitation intervention for children with CP, informing clinical practice guidelines and therapeutic decision-making. The findings contribute to our understanding of the potential benefits of treadmill training in improving motor function, balance, and spasticity in this

Eligibility criteria: Inclusion Criteria:

* Age 4 -12 years.
* Children having, I-II on GMFCM.
* Children diagnosed with spastic cerebral palsy.
* Children with will cognitive behavior

Exclusion Criteria:

* Misdiagnosed or not conform to Cerebral palsy.
* Children should be medically un stable uncontrolled seizures
* The children with mental retardation or other neurological disorders.
* Children with serve respiratory dysfunction, multiple contracture.
* Children with prior undone this type of training.
* Children with taking medication like muscle relaxant.
* Children having communication or hearing issues.

Primary outcomes:
measure: Pediatric Balance scale to Measure balance
timeFrame: 12th weeks study , 1st reading will be take on baseline than after 4 weeks ,8weeks & 12weeks
Secondary outcomes:
measure: Modified Ashworth Scale to measure spasticity
timeFrame: 12th weeks study , 1st reading will be take on baseline than after 4 weeks ,8weeks & 12weeks
measure: GMFCS (Gross Motor Function Classification System) to measure the motor functions
timeFrame: 12th weeks study ,1st reading will be take on baseline than after 4 weeks ,8weeks & 12weeks
Other outcomes:
Locations:
city: Peshawar
country: Pakistan
facility: Helping Hand Rehabilitation center
state: KP
Study officials:
affiliation: Riphah International University
name: Waqar Ahmad Awan, Phd
role: PRINCIPAL_INVESTIGATOR
affiliation: Riphah International University
name: Numan Sadiq, MS SPT
role: PRINCIPAL_INVESTIGATOR
References:
citation: Grecco LA, Zanon N, Sampaio LM, Oliveira CS. A comparison of treadmill training and overground walking in ambulant children with cerebral palsy: randomized controlled clinical trial. Clin Rehabil. 2013 Aug;27(8):686-96. doi: 10.1177/0269215513476721. Epub 2013 Mar 15.
citation: Chrysagis N, Skordilis EK, Stavrou N, Grammatopoulou E, Koutsouki D. The effect of treadmill training on gross motor function and walking speed in ambulatory adolescents with cerebral palsy: a randomized controlled trial. Am J Phys Med Rehabil. 2012 Sep;91(9):747-60. doi: 10.1097/PHM.0b013e3182643eba.
citation: Mutlu A, Krosschell K, Spira DG. Treadmill training with partial body-weight support in children with cerebral palsy: a systematic review. Dev Med Child Neurol. 2009 Apr;51(4):268-75. doi: 10.1111/j.1469-8749.2008.03221.x. Epub 2009 Jan 21.
citation: Mattern-Baxter K. Effects of partial body weight supported treadmill training on children with cerebral palsy. Pediatr Phys Ther. 2009 Spring;21(1):12-22. doi: 10.1097/PEP.0b013e318196ef42.
citation: Mattern-Baxter K, Bellamy S, Mansoor JK. Effects of intensive locomotor treadmill training on young children with cerebral palsy. Pediatr Phys Ther. 2009 Winter;21(4):308-18. doi: 10.1097/PEP.0b013e3181bf53d9.