Clinical trial NCT05075525: EFFECT OF HIGH INTENSITY LASER IN PATELLOFEMORAL PAIN SYNDROME
Official title: EFFECT OF HIGH INTENSITY LASER THERAPY ON PAIN AND LOWER EXTREMITY FUNCTION IN PATELLOFEMORAL PAIN SYNDROME
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Physical Therapy
Orthopedic Disorder
Keywords: Patellofemoral pain
High intensity laser therapy
Lead sponsor: Istanbul Medipol University Hospital
Sponsor class: OTHER
First posted: 2021-10-12
Enrollment: 45
Sex: ALL
Minimum age (years): 25
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The aim of this study is to investigate the effectiveness of high-intensity laser therapy on pain and lower extremity function in the treatment of patellofemoral pain syndrome.

Detailed description: Participants between the ages of 25-45 who were diagnosed with Unilateral patellofemoral pain syndrome by the doctor will be included in the study. Also positive Clarke's test and patellar compression tests will be determined as inclusion criteria. The 45 participants will be randomly divided into three groups. Both groups will receive 2 weeks (5 sessions per week) of therapy. First group patients underwent High Intensity Laser Therapy (HILT) and exercises. Second group patients will be treated by transcutaneous electrical nerve stimulation(TENS), ultrasound (US) and exercise for 10 sessions. Also In the third group patients will be treated with ultrasound (US),interferential current stimulation and exercise. All groups receive the same exercise exercise protocol including muscle strengthening and flexibility training for 12 weeks. The outcomes will be pain intensity measured by visual analog scale (VAS) , knee flexion range of motion (FROM), timed up and go test (TUG),muscle strength measured with handheld dynamometer, Pressure Pain Threshold with an algometry and functionality of knee measured by the Lower extremity functional scale and Kujala patellofemoral questionnaire. Statistical analyzes will be performed to compare amounts at baseline, immediately after treatment, and after 12 weeks.

Eligibility criteria: Inclusion Criteria:

* Unilateral patellofemoral pain syndrome diagnosed by a doctor
* 25-45 years old
* pain from prolonged sitting, climbing and descending stairs, running,knee bend more than 3 months
* positive patellar compression and clarke's tests.

Exclusion Criteria:

* Previous knee pain, trauma, surgery and other joint diseases,
* Knee ligament, bursa, meniscus and synovial fold injury or dysfunction
* Osteoarthritis in the knee joint,
* Neurological problems that may affect walking
* Pregnancy
* No chronic disease
* Malignancy,
* Presence of infection

Primary outcomes:
measure: Pain status
timeFrame: 5 minutes
measure: Range of motion assesment
timeFrame: 10minutes
measure: Functionality
timeFrame: 5 minutes
measure: Muscle stength assesment
timeFrame: 10 minutes
measure: Pain threshold assessment
timeFrame: 10 minutes
measure: Severity and function of patellofemoral pain
timeFrame: 5 minutes
measure: Function of lower extremity
timeFrame: 10 minutes
Secondary outcomes:
Other outcomes:
Locations:
city: Istanbul
country: Turkey
facility: Ozge Ozlu
state: Beykoz
Study officials:
affiliation: Medipol University
name: OZGE OZLU
role: PRINCIPAL_INVESTIGATOR
References:
citation: Nazari A, Moezy A, Nejati P, Mazaherinezhad A. Efficacy of high-intensity laser therapy in comparison with conventional physiotherapy and exercise therapy on pain and function of patients with knee osteoarthritis: a randomized controlled trial with 12-week follow up. Lasers Med Sci. 2019 Apr;34(3):505-516. doi: 10.1007/s10103-018-2624-4. Epub 2018 Sep 3.