Clinical trial NCT05825638: Evolution of Pulsed Oxygen Saturation During Interval Training Compared to Continuous Training in COPD Patients
Official title: Evolution of Pulsed Oxygen Saturation Throughout an Interval Training Session Compared to a Continuous Training Session in Patients With Chronic Obstructive Pulmonary Disease With Exercise-induced Oxygen Desaturation.
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: COPD
Exercise
Pulmonary Rehabilitation
Desaturation of Blood
Keywords: COPD
Pulmonary rehabilitation
Interval training
Lead sponsor: Groupe Hospitalier du Havre
Sponsor class: OTHER
Collaborators: name: Medrinal Clement
name: Combret Yann
name: Machefert Margaux
First posted: 2023-04-24
Enrollment: 12
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_CROSSOVER
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Patients with COPD who meet the inclusion criteria will be offered to participate in this study during a pulmonary rehabilitation programme which will take place in the pneumology rehabilitation department of the Le Havre Hospital. If the patient wishes to participate in the study, he/she will be given an information note containing a declaration of non-opposition which he/she will have to complete and sign.

Brief summary: A problem often observed during exercise training is oxygen desaturation exclusively during exercise in some patients. In the case of exercise-induced desaturation, it may be suggested to train these patients in interval training to limit exercise-induced desaturation. Interval training consists of alternating active phases of short duration (often 30 seconds to 1 minute) followed by a short active or passive recovery phase of equivalent duration to the previous phase. Investigators therefore hypothesise that interval training on a cycloergometer or treadmill can limit exercise-induced desaturation in COPD patients.

The aim of the study is to observe the evolution of pulsed oxygen saturation between a continuous training session and a interval training session.


Eligibility criteria: Inclusion Criteria:

* a diagnosis of COPD
* participating in a pulmonary rehabilitation programme
* with an exercise-induced desaturation less than 90%
* no oxygen supplementation

Exclusion Criteria:

* Under 18 years of age
* Pregnant woman
* Person not affiliated to a health insurance regime or not benefiting from a social security regime
* Patient under curatorship, guardianship or safeguard of justice
* Patient speaking a language other than French
* Patient with severe hypoxaemia (SpO2 ≤ 80%) during exercise
* Patient having had a moderate or severe exacerbation (hospitalisation for respiratory reasons) in the previous 4 weeks
* Patients with orthopaedic, rheumatic, vascular or neurological pathology limiting their ability to make an effort
* Breastfeeding women

Primary outcomes:
measure: Difference in oxygen pulsed saturation
timeFrame: One week
Secondary outcomes:
measure: Difference in oxygen pulsed saturation
timeFrame: One week
measure: Difference in peripheral muscle oxygenation
timeFrame: One week
measure: Difference in respiratory rate
timeFrame: One week
measure: Difference in tidal volume
timeFrame: One week
measure: Difference in inspiratory capacity
timeFrame: One week
measure: Difference in Dyspnea
timeFrame: One week
measure: Difference in muscle discomfort
timeFrame: One week
Other outcomes:
Locations:
city: Le Havre
country: France
facility: Groupe Hospitalier du Havre
state: Normandie
Study officials:
affiliation: Groupe Hospitalier du Havre
name: Guillaume Prieur, PT, PhD
role: PRINCIPAL_INVESTIGATOR
References: