Clinical trial NCT04941820: The Impact of Clinical Pharmacist in the Identification and Management of Treatment Related Problems in the Surgery Ward
Official title: The Impact of Clinical Pharmacist in the Identification and Management of Treatment Related Problems in the Surgery Ward
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Surgical Patients
Keywords: clinical pharmacist
general surgical ward
RCT
SICU
Lead sponsor: University of Jordan
Sponsor class: OTHER
First posted: 2021-06-28
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: All patients were followed up prospectively for their length of hospital stay, and recommendations concerning each identified TRP were provided to the surgeons responsible for patients in the intervention group. Likewise, patient counseling and encouraging adherence to therapy were provided solely to patients in the intervention group. Patients in the control group received usual care by the surgical team without a coordinated contribution from the clinical pharmacist.
Primary purpose: TREATMENT

Brief summary: Patients in the surgery ward are at risk of morbidity and mortality from various types of treatment-related problems (TRPs). The primary aim of this study is to assess the impact of the clinical pharmacist in the identification and management of TRPs in the surgery ward.

Detailed description: Patients were randomly assigned to intervention (n=50) and usual care (n=50) arms. The clinical pharmacist assessed the types, frequencies, and clinical significance of TRPs for all recruited patients at baseline. Patients and treating surgeons in the intervention arm received recommendations concerning the identified TRPs, while the usual care arm did not. The number of TRPs was reevaluated at follow-up.

Eligibility criteria: Inclusion Criteria:

* Admission for elective, urgent, or emergency surgery
* age 18 years or older
* Expected length of stay of 3 days or more in the general surgical ward or the SICU

Exclusion Criteria:

* Pregnancy, breastfeeding, drug or alcohol abuse, active malignancy, or admission for plastic surgery

Primary outcomes:
measure: Acceptance rate of clinical pharmacist's recommended interventions
timeFrame: 19-week
measure: Implementation rate of clinical pharmacist's recommended interventions
timeFrame: 19-week
measure: The impact of the clinical pharmacist on the identification and management of TRPs in the surgery ward
timeFrame: 19-week
Secondary outcomes:
measure: Surgeons' attitudes and satisfaction towards the provided clinical pharmacy services
timeFrame: 19-week
Other outcomes:
Locations:
city: Amman
country: Jordan
facility: University of Jordan
Study officials:
affiliation: School of Pharmacy, The University of Jordan, Amman, Jordan
name: Hiba I. Al Fahmawi, PharmD, MSc
role: STUDY_DIRECTOR
References:
citation: AbuRuz SM, Bulatova NR, Yousef AM. Validation of a comprehensive classification tool for treatment-related problems. Pharm World Sci. 2006 Aug;28(4):222-32. doi: 10.1007/s11096-006-9048-0. Epub 2006 Oct 26.
citation: Basheti IA, Ayasrah SM, Ahmad M. Identifying treatment related problems and associated factors among hospitalized post-stroke patients through medication management review: A multi-center study. Saudi Pharm J. 2019 Feb;27(2):208-219. doi: 10.1016/j.jsps.2018.10.005. Epub 2018 Oct 19.
citation: Bilal AI, Tilahun Z, Beedemariam G, Ayalneh B, Hailemeskel B, Engidawork E. Attitude and satisfaction of health care providers towards clinical pharmacy services in Ethiopia: A post-deployment survey. J Pharm Policy Pract. 2016 Mar 8;9:7. doi: 10.1186/s40545-016-0058-6. eCollection 2016.
citation: Hepler CD. Clinical pharmacy, pharmaceutical care, and the quality of drug therapy. Pharmacotherapy. 2004 Nov;24(11):1491-8. doi: 10.1592/phco.24.16.1491.50950.