Clinical trial NCT05848167: Senile Osteoporotic Fractures Cohort Study（SOFCS）
Official title: Senile Osteoporotic Fractures Cohort Study
Study type: OBSERVATIONAL
Overall status: RECRUITING
Conditions: Osteoporotic Fractures
Keywords: Senile osteoporotic fracture,Cohort study,mechanism,outcome
Lead sponsor: Suzhou Municipal Hospital
Sponsor class: OTHER
First posted: 2023-05-08
Enrollment: 2000
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Elderly patients after operation of osteoporotic fracture.

Brief summary: Osteoporotic fracture is one of the main causes of disability and death in elderly patients. Specific disease cohort study is an important basis for accurate prevention and treatment of senile osteoporotic fractures. Investigators plan to collect and manage the baseline and clinical information of more than 2000 elderly patients with osteoporotic fractures after surgery through the platform of special disease collaborative prevention and treatment system and medical record database of Suzhou Municipal Hospital in two years, and carry out short-term and long-term follow-up observation.

Detailed description: Osteoporotic fracture is one of the main causes of disability and death in elderly patients. Compared with patients with no history of fractures, the risk of a second fracture after an initial fracture doubled, with a fatality rate of up to 34.8%. There has been a lot of progress in the diagnosis and treatment of osteoporotic fractures in the elderly. However, there are few reports on the diagnosis and treatment of osteoporotic fractures in the elderly after surgery. Based on previous studies, it is found that the re-fracture after operation of osteoporotic fracture in the elderly is not only directly caused by the fall, but also caused by the interaction of multiple risk factors including environmental factors, physiological factors and neuroskeletal musculoskeletal system. Therefore, it is of great significance to break the traditional diagnosis and treatment mode, improve the diagnosis and treatment effect, and save medical resources to carry out research on the disease characteristics, rules and risk warning after senile osteoporotic fracture operation. Specific disease cohort study is an important basis for accurate prevention and treatment of senile osteoporotic fractures. Investigators plan to collect and manage the baseline and clinical information of more than 2000 elderly patients with osteoporotic fractures after surgery through the platform of special disease collaborative prevention and treatment system and medical record database of Suzhou Municipal Hospital in two years, and carry out short-term and long-term follow-up observation.

Eligibility criteria: Inclusion Criteria:

1. Patients ≥65 years old
2. Patients with osteoporosis
3. No gender limitation

Exclusion Criteria:

1. \< 65 years old;
2. Non-osteoporotic fracture;
3. Alzheimer's disease;
4. Bone tumors.

Primary outcomes:
measure: Bone mineral density
timeFrame: two years
Secondary outcomes:
Other outcomes:
Locations:
city: Suzhou
country: China
facility: Suzhou Municipal Hospital
state: Jiangsu
Study officials:
affiliation: Suzhou Municipal Hospital
name: Hao Y feng, doctor
role: STUDY_CHAIR
References: