Clinical trial NCT06495840: Postoperative Anxiety and Depression Among Older Chinese Patients
Official title: Postoperative Anxiety and Depression Among Older Chinese Patients: a Prospective Observational Study Based on a Multi-center Perioperative Database in China
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Depression
Anxiety
Elderly Patients
Non-cardiac Surgery
Lead sponsor: Chinese PLA General Hospital
Sponsor class: OTHER
Collaborators: name: Beijing Tiantan Hospital
name: Peking University First Hospital
name: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
name: Xiangya Hospital of Central South University
name: Beijing Anzhen Hospital
name: Central South University
name: Peking University People's Hospital
name: Zhejiang University
name: Fudan University
name: Sun Yat-sen University
name: Wuhan Union Hospital, China
name: China-Japan Friendship Hospital
name: The Affiliated Hospital Of Guizhou Medical University
name: First Affiliated Hospital of Xinjiang Medical University
name: First Affiliated Hospital of Guangxi Medical University
name: Taihe Hospital
name: Zhejiang Provincial People's Hospital
name: Shanghai Zhongshan Hospital
First posted: 2024-07-11
Enrollment: 8590
Sex: ALL
Minimum age (years): 65
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Elderly patients (aged ≥ 65 years) who completed the anxiety and depression assessment after the elective noncardiac, non-neurosurgical surgery were included in this study.

Brief summary: A multicenter, prospective observational study to describe the socioeconomic characteristics and the occurrence of postoperative anxiety and depression in the Chinese old population.

Detailed description: As China's population ages, the proportion of elderly people undergoing surgery increases. Perioperative anxiety and depression, particularly in elderly patients, is common and associated with multiple medical and social adversities. Previous studies have found a 31 percent risk of anxiety and 29 percent risk of depression in older perioperative patients. However, nationally representative epidemiological data for postoperative anxiety and depression, in particular elderly patients undergoing non-cardiac surgery, are unavailable in China. Therefore, providing nationwide epidemiological data on postoperative anxiety and depression in Chinese elderly patients provides a valuable opportunity for policy makers and health care professionals to optimize the management of geriatric mental health in China.

Eligibility criteria: Inclusion Criteria:

1. elderly patients (age ≥ 65 years)
2. undergoing elective surgery with a planned overnight hospital stay following surgery
3. non-cardiac surgery, non-neurosurgical surgery

Exclusion Criteria:

1. patients fully refused to participate in the study
2. patients with severe dementia, language disorder, severe hearing or visual impairment, coma, and end-stage status
3. patients whose surgeries were canceled
4. history of previous severe mental illness or long-term use of psychotropic medications
5. patients admitted to ICU immediately after surgery
6. patients who died within 7 days after surgery
7. patients who did not complete the scale assessment

Primary outcomes:
measure: Anxiety
timeFrame: within 7 days after surgery
measure: Depression
timeFrame: within 7 days after surgery
Secondary outcomes:
Other outcomes:
Locations:
city: Beijing
country: China
facility: First Medical center of Chinese PLA General Hospital
Study officials:
affiliation: Chinese PLA General Hospital
name: Weidong Mi, PhD
role: STUDY_CHAIR
References: