Clinical trial NCT05015062: Effectiveness of a Mobile-based HIV Prevention Intervention Involving Incentive Policy for Doctors in Liangshan, China
Official title: Effectiveness of a Mobile-based HIV Prevention Intervention for Rural and Low-income Population Involving Incentive Policy for Doctors in Liangshan, China: a Randomized Controlled Trial Protocol
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: HIV/AIDS
Lead sponsor: Peking University
Sponsor class: OTHER
First posted: 2021-08-20
Enrollment: 4000
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: FACTORIAL
Primary purpose: PREVENTION

Brief summary: This study will be carried out in Liangshan Yi Autonomous Prefecture, Sichuan province, China, using a single-blinded randomized controlled trial design to measure the effects of a mobile-based HIV-related information intervention on group HIV/AIDS prevention. Village doctors will be responsible for sending the HIV-related health education information to the participants. The aim of this study is to develop a generalizable, effective, acceptable, and convenient mobile-based information intervention model to improve HIV-related knowledge, attitudes, practices, and health outcomes in poverty-stricken areas in China and measure the impact of incentive policies on the work of village doctors in Liangshan, China.


Eligibility criteria: Inclusion Criteria:

* aged 18 years or older
* has mobile phone with internet service
* has and use WeChat and TikTok account regularly
* willing to provide informed consent
* speak Mandarin Chinese or Yi ethnic group's language

Exclusion Criteria:

* diagnosed with psychiatric disorders
* diagnosed with severe cognitive impairment
* diagnosed with severe physical disabilities
* has already attended or is currently attending another intervention program
* plan on moving out of Liangshan in the 18-month study period

Primary outcomes:
measure: HIV-related knowledge improvement
timeFrame: 18 months
measure: Comparison of the effectiveness of different financial compensations
timeFrame: 18 months
Secondary outcomes:
measure: Effectiveness of secondary knowledge transmission: HIV-related knowledge improvement of the participants' family members
timeFrame: 18 months
measure: Behavioral changes: condom use
timeFrame: 18 months
measure: Behavioral changes: substance use
timeFrame: 18 months
measure: Health outcomes: HIV prevalence
timeFrame: 18 months
measure: Health outcomes: mental health
timeFrame: 18 months
measure: Health outcomes: all-cause mortality
timeFrame: 18 months
measure: Social factors: quality of life
timeFrame: 18 months
measure: Social factors: stigma towards HIV
timeFrame: 18 months
measure: Social factors: perception of social support
timeFrame: 18 months
measure: Retention of HIV-related knowledge
timeFrame: 18 months
measure: Feasibility: participants' use of social media applications
timeFrame: 18 months
measure: Level of engagement
timeFrame: 18 months
measure: Study's acceptability and satisfaction
timeFrame: 18 months
measure: Cost-effectiveness of the intervention:
timeFrame: 18 months
Other outcomes:
Locations:
Study officials:
affiliation: Peking University
name: Guoen Liu
role: PRINCIPAL_INVESTIGATOR
References:
citation: Wang M, Liu G, Chen X, Ma S, Chen C. Effectiveness of a mobile-based HIV prevention intervention for the rural and low-income population involving incentive policy to doctors in Liangshan, China: a randomized controlled trial protocol. BMC Public Health. 2022 Sep 5;22(1):1682. doi: 10.1186/s12889-022-13930-2.