Clinical trial NCT04308057: Exploring the Effects of Aquatic Exercise on Cardiovascular Function in Older Adults
Official title: Exploring the Effects of Aquatic Exercise on Cardiovascular Function in Older Adults
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cardiovascular Diseases
Lead sponsor: Sheffield Hallam University
Sponsor class: OTHER
First posted: 2020-03-13
Enrollment: 100
Sex: ALL
Minimum age (years): 55
Maximum age (years): 75
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Observational model: OTHER
Time perspective: OTHER
Sampling method: PROBABILITY_SAMPLE
Study population: Group A (n=20) consists of participants engaging in swimming or other aquatic, primarily aerobic-based, training regimes for more than 2 times a week, for more than 6 months, at the time of the assessments. Similarly, Group B (n=20) consists of participants engaging in land-based, primarily aerobic training regimes (e.g. aerobic exercise) for more than 2 times a week, for a period longer than 6 months, at the time of the assessments. Group C (n=20) consists of participants who were cengaging in both land-based and aquatic, primarily aerobic, exercise regimes on an equal basis, for more than 6 months, while Group D (n=40) consists of people who were sedentary (e.g., defined as undertaking less than 60 min of structured/planned physical activity per week), for a period longer than 6 months.

Brief summary: Cardiovascular ageing is implicated in the development of cardiovascular disease (CVD). Aquatic exercise is being considered as a co-adjuvant form of rehabilitation, but there is limited evidence for its cardiovascular risk-reduction properties for older people. Our study aims to address this by exploring the cardiovascular effects of long-term aquatic exercise in older adults in comparison to those who are either inactive or engaged in land-based/mixed training by measurement of micro- and macro-circulation.


Eligibility criteria: Inclusion Criteria:

* being over 55 years of age and normotensive (e.g., \<140/90 mm Hg).

Exclusion Criteria:

* any overt chronic disease which would affect microvascular functioning,
* anaemia (irrespective of whether an iron supplementation course is followed or not)
* a recent (3 months' ago) major surgery
* None of the participants were undertaking high intensity interval training of any form.

Primary outcomes:
measure: Nitric oxide-mediated, macro (arterial)- circulatory function.
timeFrame: Baseline.
measure: Nitric oxide-mediated, macro (arterial)- circulatory function.
timeFrame: 8 weeks.
Secondary outcomes:
measure: Microcirculatory function
timeFrame: Baseline.
measure: Microcirculatory function
timeFrame: 8 weeks.
measure: Anthropometry - 1
timeFrame: Baseline.
measure: Anthropometry - 2
timeFrame: Baseline.
measure: Anthropometry - 1
timeFrame: 8 weeks.
measure: Anthropometry - 2
timeFrame: 8 weeks.
measure: EQ-5D-5L
timeFrame: Baseline.
measure: EQ-5D-5L
timeFrame: 8 weeks.
measure: SF-IPAQ
timeFrame: Baseline.
measure: SF-IPAQ
timeFrame: 8 weeks.
measure: Q-Risk
timeFrame: Baseline.
measure: Q-Risk
timeFrame: 8 weeks.
measure: Feasibility outcome - 1
timeFrame: Baseline
measure: Feasibility outcome - 2
timeFrame: 8 weeks
measure: Feasibility outcome - 3
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Sheffield
country: United Kingdom
facility: Sheffield Hallam University
state: Yorkshire
Study officials:
affiliation: Sheffield Hallam University
name: Markos Klonizakis, D.Phil.
role: PRINCIPAL_INVESTIGATOR
References: