Clinical trial NCT03794674: Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index
Official title: Validation of a Record-based Frailty Assessment According to the Multidimensional Prognostic Index
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Frail Elderly Syndrome
Keywords: Multidimensional Prognostic Index
Frailty
Geriatric
Elderly
Aged
+75
Comprehensive Geriatric Assessment
Lead sponsor: University of Aarhus
Sponsor class: OTHER
First posted: 2019-01-07
Enrollment: 92
Sex: ALL
Minimum age (years): 75
Standard ages: OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: OTHER
Sampling method: NON_PROBABILITY_SAMPLE
Study population: The study group comprises medical patients acutely admitted to the Department of Cardiology and the Department of Infectious Diseases, Aarhus University Hospital.

Brief summary: Background Various phenotype and cumulative frailty assessment tools have been developed and compared in research. For use in an in-hospital setting, a cumulative and graded frailty assessment method is preferred in order to identify subgroups of patients at risk of adverse events during discharge and transition to primary care. Comprehensive Geriatric Assessment (CGA) is the gold standard to assess frailty. Most medical wards have limited access to specialized geriatric team support capable of performing CGA. Thus in these wards there is a need for a CGA based instrument to identify the frail patients and to quantify the level of frailty. The Multidimensional Prognostic Index (MPI) is based on CGA and is a comprehensive cumulative deficit frailty assessment tool validated in a Danish geriatric department. MPI is fully applicable in the everyday clinical work and supplies useful information to clinicians. It can predict readmission and death, and it is well-suited to assess the degree of frailty. Enabling identification of patients at risk of adverse events facilitates targeting of the interventions in order to improve patient outcomes. The MPI is a bedside assessment. However, in observational record-based research the patient is not accessible for the researcher. To assess and identify hospitalized frail patients retrospectively for clinical research, a valid record-based frailty assessment method is needed. The aim of this study is to compare the accuracy of a record-based MPI assessment with a bedside performed MPI assessment in order to use the record-based MPI when access to bedside MPI is impossible.


Eligibility criteria: Inclusion Criteria:

* Acutely admitted to one of the two medical departments listed below
* Aged 75 years or older
* Living within the municipality of Aarhus

Exclusion Criteria:

* Included in any other kind of follow-up schemes
* Already included in this study
* Declared terminally ill or undergoing palliative care at admission
* Admitted from one specific temporary nursing home with geriatric medical assistance (Vikærgården)
* Discharge or transfer to another department, including hospice
* The patient does not want to participate in the MPI-screening process

Primary outcomes:
measure: Sumscore
timeFrame: 1 day
Secondary outcomes:
Other outcomes:
Locations:
city: Aarhus
country: Denmark
facility: Aarhus University
Study officials:
affiliation: Aarhus University Hospital and Aarhus University
name: Troels Hansen, MD
role: PRINCIPAL_INVESTIGATOR
References:
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