Clinical trial NCT03712592: Physiological Constraints Associated With Trail Running
Official title: Physiological Constraints Associated With Trail Running
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Muscle Fatigue
Lead sponsor: University Hospital, Grenoble
Sponsor class: OTHER
Collaborators: name: University Grenoble Alps
First posted: 2018-10-19
Enrollment: 83
Sex: ALL
Minimum age (years): 18
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NON_RANDOMIZED
Intervention model: PARALLEL
Primary purpose: BASIC_SCIENCE

Brief summary: The practice of mountain running or "trail" is in full development in France and elsewhere in the world. This sporting practice associates specific physiological constraints related in particular to the duration of the efforts made (several hours) and to the ground (important elevation, technical ground, average altitude). Some studies have allowed the last 10 years to initiate the exploration of the physiological consequences of this type of practice, especially from a muscular point of view. However, some important questions remain to be clarified such as the impact of these sports events on fatigue and muscle recovery, cardiovascular, energy and water balance disturbances caused, induced sleep changes and the kinetics of recovery of the various parameters. . These elements remain in particular to be studied in very different racing contexts as currently developed by the organizers, namely race in one stage from long to very long distances (40 to 160 km) and race in stages (4 days, 4 x 40 km) as encountered in the Grenoble UT4M race (Ultra Tour des 4 Massifs).


Eligibility criteria: Inclusion Criteria:

* Man or woman
* 18-55 years
* Absence of chronic cardiovascular, respiratory, metabolic or neuromuscular disease
* \> 3 years of trail running (at least 1 race\> 40 km / year completed and a race\> 100 km completed (trail group 160 km)
* Medical certificate of no contraindication to the practice of the trail
* Subjects available in Grenoble before and within 15 days after the race
* Subjects affiliated to a social security scheme
* Subjects able to sign informed consent.

Exclusion Criteria:

* Cardiorespiratory, metabolic and neurological diseases
* Non-Echogenic Subjects
* Subjects with chronic sleep disorders
* Psychiatric pathologies or ATCD of behavioral disorders
* Persons refusing to sign the information sheet and the participation agreement,
* persons under guardianship or not subject to a social security scheme,
* Pregnant woman, parturient, breastfeeding mother
* Person deprived of liberty by judicial or administrative decision,
* Person subject to a legal protection measure, who can not be included in clinical trials.

Primary outcomes:
measure: Quantification of the level of ankle extensors fatigue induced by trail
timeFrame: one month and 12 days
measure: Quantification of the level of knee extensors fatigue induced by trail
timeFrame: one month and 12 days
measure: Quantification of the level of ankle extensors fatigue induced by trail
timeFrame: one month and 12 days
Secondary outcomes:
Other outcomes:
Locations:
city: Grenoble
country: France
facility: CHU Grenoble-Alpes
Study officials:
References: