Clinical trial NCT06913543: Effect of Open Kinetic CKE Exercises With NES in Patients With Post-ACL Reconstruction Surgery
Official title: Effect of Open Kinetic Chain Knee Extension Exercises With Neuromuscular Electrical Stimulation in Patients With Post-ACL Reconstruction Surgery
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Anterior Cruciate Ligament Injuries
Lead sponsor: Superior University
Sponsor class: OTHER
First posted: 2025-04-06
Enrollment: 58
Sex: ALL
Minimum age (years): 18
Maximum age (years): 45
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: "Anterior cruciate ligament (ACL) reconstruction is a commonly performed surgical procedure for restoring knee stability in patients following ACL injuries. Despite surgical success, postoperative rehabilitation remains crucial for improving functional outcomes, addressing quadriceps strength deficits, and reducing recovery time.

Detailed description: This study investigates the combined impact of open kinetic chain (OKC) knee extension exercises and neuromuscular electrical stimulation (NMES) on the functional recovery of post-ACL reconstruction patients. This randomized clinical trial involves 58 patients, divided into two groups: an experimental group receiving OKC knee extension exercises combined with NMES and a control group receiving OKC exercises alone. Functional outcomes, range of motion (ROM), and patient-reported outcomes (PROs) are assessed using validated tools.

Eligibility criteria: Inclusion Criteria:

* Both genders aged 18-45 years
* Subjects who have undergone unilateral primary ACL reconstruction surgery
* Subjects who are exactly 4 weeks post-surgery at the start of the study
* Subjects who received a hamstring tendon autograft or patellar tendon graft for ACL reconstruction
* Subjects cleared by a physician to begin open kinetic chain exercises in their rehabilitation program
* Subjects who are generally healthy with no significant comorbidities that could interfere with rehabilitation
* Willingness to provide informed consent and commit to the entire duration of the study

Exclusion Criteria:

* Presence of additional knee injuries (e.g., meniscal tears, collateral ligament injuries) that might affect rehabilitation
* History of prior ACL injury or reconstruction on the same knee
* Patients who underwent reconstruction of other ligaments along with the ACL
* Presence of conditions (e.g., rheumatoid arthritis, osteoarthritis, uncontrolled diabetes) that could influence recovery
* Any significant injury or surgery to the opposite knee within the last six months
* Factors that indicate a high risk of non-compliance with the rehabilitation protocol, such as poor availability, or lack of commitment to follow the exercise regimen
* Conditions affecting neuromuscular control that could interfere with exercise performance or rehabilitation response

Primary outcomes:
measure: Lysholm Knee Scoring Scale
timeFrame: 12 Months
measure: Universal Goniometer
timeFrame: 12 Months
Secondary outcomes:
Other outcomes:
Locations:
city: Faisalābad
country: Pakistan
facility: MOVEBETTER 14-A Koh-e-Noor Road, Basement Salt N Pepper
state: Punjab
Study officials:
References: