Clinical trial NCT03926325: Baseline Investigation of Patients With Cardiac Arrest in China
Official title: Baseline Investigation of Patients With Cardiac Arrest in China
Study type: OBSERVATIONAL
Overall status: UNKNOWN
Conditions: Cardiac Arrest
Lead sponsor: Qilu Hospital of Shandong University
Sponsor class: OTHER
Collaborators: name: Hainan Medical College
name: Jinan Emergency Medical Center
name: Wenshang County People's Hospital
name: The Affiliated Hospital of Xuzhou Medical University
name: Xuzhou Ambulance Center
name: The First Affiliated Hospital of Anhui Medical University
name: Hefei Emergency Medical Center
name: Second Affiliated Hospital, School of Medicine, Zhejiang University
name: Hangzhou Emergency Medical Center
name: RenJi Hospital
name: Shanghai Changzheng Hospital
name: Shanghai Emergency Medical Center
name: First Affiliated Hospital of Fujian Medical University
name: The First Affiliated Hospital of Nanchang University
name: China-Japan Friendship Hospital
name: Chinese Academy of Medical Sciences, Fuwai Hospital
name: Beijing Friendship Hospital Affiliated to the Capital University of Medical Sciences
name: Beijing Children's Hospital
name: Beijing Emergency Medical Center
name: Beijing Red Cross Emergency Rescue Center
name: Tianjin Medical University General Hospital
name: Tianjin Emergency Medical Center
name: The Affiliated Hospital of Inner Mongolia Medical University
name: Hohhot 120 Emergency Medical Center
name: Siziwang Banner People's Hospital of Inner Mongolia
name: First Hospital of Qinhuangdao
name: Qinhuangdao Emergency Dispatching Center
name: The First Affiliated Hospital of Shanxi Medical University
name: Taiyuan Emergency Medical Center
name: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
name: Guangzhou Emergency Medical Command Center
name: Haikou Emergency Medical Center
name: People's Hospital of Wanning
name: First Affiliated Hospital of Guangxi Medical University
name: Nanning Emergency Medical Center
name: Renmin Hospital of Wuhan University
name: Wuhan Emergency Medical Center
name: Qianjiang Central Hospital
name: Henan Provincial People's Hospital
name: Zhenzhou Emergency Medical Center
name: Hunan Provincial People's Hospital
name: The First Hospital of Jilin University
name: Changchun Emergency Medical Center
name: Nong'an County People's Hospital
name: First Hospital of China Medical University
name: Shenyang Emergency Center
name: First Affiliated Hospital of Harbin Medical University
name: Heilongjiang Emergency Medical Center
name: Santai County People's Hospital
name: Chongqing Emergency Medical Center
name: Emergency Center of Yunan Province
name: The Affiliated Hospital Of Guizhou Medical University
name: Nyingchi People's Hospital
name: First Affiliated Hospital of Xinjiang Medical University
name: Lanzhou University Second Hospital
name: Wushan County People's Hospital
name: People's Hospital of Ningxia Hui Autonomous Region
name: Yinchuan Emergency Medical Center
name: Qinghai People's Hospital
name: Second Affiliated Hospital of Xi'an Jiaotong University
name: Xi'an Emergency Medical Center
name: Fudan University
name: National Center for Cardiovascular Disease
name: Beijing Institute of Heart, Lung and Blood Vessel Diseases
name: Capital Medical University
name: Peking University Third Hospital
name: Beijing Chao Yang Hospital
name: National Center for Chronic and Noncommunicable Disease Control and Prevention, China CDC
name: National Health Commission of the People's Republic of China, Statistical information center
name: Xiangya Hospital of Central South University
name: West China Hospital
name: Chang shu No.1 People's Hospital
First posted: 2019-04-24
Enrollment: 200000
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: consecutive patients with cardiac arrest

Brief summary: BASIC is a perspective, multicentre and large-scale registry focusing on of patients suffering a cardiac arrest in China. The aims of the study are to establish the monitoring sites covering out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) in urban and rural areas in 7 regions (East China, North China, South China, Central China, Northeast China, Southwest China and Northwest China) around China, to collect data from cardiac arrest patients, and to describe basic characteristics, treatments, outcomes, incidences and risk factors of OHCA and IHCA in China.


Eligibility criteria: Inclusion Criteria:

1. OHCA: Every patient who suffered a cardiac arrest that occurred in any location other than a hospital, and was attended and/or treated by an EMS.
2. IHCA: Every patient who suffered a cardiac arrest in hospital.
3. the representative population-based survey: Every patient who suffered a cardiac arrest in the selected cities or suburbs.

Exclusion Criteria:

1. OHCA: 1)The out-of-hospital cardiac arrest patients who were taken to the hospital by their family members; 2) Bystanders suspected cardiac arrest, but the ROSC was achieved without defibrillation or resuscitation by EMS.
2. IHCA: The patient who suffered a cardiac arrest that occurred out-of-hospital and then transferred to the hospital.

Primary outcomes:
measure: incidence of OHCA treated by EMS
timeFrame: Latest data inclusion June 30, 2022
measure: incidence of IHCA
timeFrame: Latest data inclusion June 30, 2022
measure: survival to hospital discharge or 30d survival of OHCA
timeFrame: at hospital discharge, 30days after cardiac arrest occurs
measure: survival to hospital discharge or 30d survival of IHCA
timeFrame: at hospital discharge, 30days after cardiac arrest occurs
measure: prevalence of favorable neurological outcome after cardiac arrest according to Cerebral Performance Category (CPC) Scale
timeFrame: at hospital discharge, 30days after cardiac arrest occurs
Secondary outcomes:
measure: survival of OHCA
timeFrame: 6 months and 1 year after cardiac arrest occurs
measure: survival of IHCA
timeFrame: 6 months and 1 year after cardiac arrest occurs
measure: prevalence of favorable neurological outcome after cardiac arrest according to Cerebral Performance Category (CPC) Scale
timeFrame: 6 months and 1 year after cardiac arrest occurs
measure: rate of return of spontaneous circulation
timeFrame: Latest data inclusion June 30,2022
Other outcomes:
Locations:
city: Jinan
country: China
facility: Qilu Hospital of Shandong University
state: Shandong
Study officials:
affiliation: Qilu Hospital of Shandong University
name: Feng Xu, Dr
role: PRINCIPAL_INVESTIGATOR
References: