Clinical trial NCT06168526: Acute Effects of Physical Activity on Cognition and Well-being in University Students
Official title: Acute Effects of Physical Activity on Cognition and Well-being in University Students: ActClass4Brain Project
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Cognitive Change
Well-Being, Psychological
Keywords: Young adults
Acute physical activity
Attention
Positive affect
Negative affect
Lead sponsor: Universitat Jaume I
Sponsor class: OTHER
First posted: 2023-12-13
Enrollment: 210
Sex: ALL
Minimum age (years): 18
Maximum age (years): 24
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Intervention model description: The study will be carried out following a crossover design with comparisons between the subjects, in which the cognition and the affective dimensions will be analysed before and after each experimental condition (acute exercise vs. sedentary control).
Primary purpose: SCREENING

Brief summary: Previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions. This highlights the importance of evaluating how physical activity can affect cognition and affective dimensions. However, to date, the dose of physical activity that could be most effective for these variables has not been established. This project aims to study the impact of acute physical activity on brain health in a university setting. Thus, this study will contribute to expand the current scientific literature on the acute effect of physical activity, a topic of great importance both in the educational field and from a public health point of view.

Detailed description: Students in the university stage face many changes in their lives. These changes, partly derived from academic activity, can cause alterations in their lifestyle and brain health (i.e., cognitive, emotional, and behavioural functioning). Due to the negative association of several indicators of brain health with academic performance during the university stage, it is of interest to promote strategies that can favour it. Among them, previous studies in young adults have shown that physical activity can generate positive emotions and improve attention, among other cognitive functions. However, to date, the dose of physical activity (i.e., type, duration, and intensity) that could be most effective for these variables has not been established. Furthermore, previous studies in the matter have been carried out in laboratories and few investigations have analysed outside them the impact of acute physical activity on brain health in university classrooms. Therefore, expanding the current scientific literature on the acute effect of physical activity is of great importance in the educational field, since it would contribute to the design of active proposals aimed at improving brain health with positive implications for students' academic performance and quality of life.

Accordingly, this project aims to carry out an acute physical activity intervention with different intensities and active breaks with students from the Jaume I University (Castellon de la Plana, Spain). More precisely, a total of 210 students between 18 and 24 years old will participate in the intervention.

To achieve it, a randomized crossover study design will be carried out with the groups of participants compensated in terms of number and sex. Attention will be assessed using the d2-R questionnaire and emotional well-being will be assessed using the Positive and Negative Affect Schedule questionnaire. The tests evaluating attention and emotional well-being will be carried out before and after each condition. The experimental conditions will be: control group (quietly sitting), light intensity (40% VO2max), moderate intensity (63% VO2max), or vigorous intensity (100% VO2max) exercise, all lasting 16 minutes. In addition, an active break will be performed at the intensity of physical activity that proves to have the greatest benefits on cognition and well-being.

Taking into account that the lifestyle of students is mainly characterized by the accumulation of prolonged periods of sedentary activity, introducing physical activity in the classroom represents an interesting opportunity for intervention from both an educational and a public health point of view.

Eligibility criteria: Inclusion Criteria:

* Not to be diagnosed with psychological and/or cognitive alterations or pathologies that may limit the understanding and following of the instructions provided by another person.
* Not to suffer physical alterations that may limit the practice of physical activity.
* To be between 18 and 24 years old.

Exclusion Criteria:

* To be diagnosed with psychological and/or cognitive alterations or pathologies that may limit the understanding and following of the instructions provided by another person.
* To suffer physical alterations that may limit the practice of physical activity.
* Not to be between 18 and 24 years old.

Primary outcomes:
measure: Attention (cognition)
timeFrame: 10 minutes before and 10 minutes after the intervention protocol
measure: Positive and negative affect (wellbeing)
timeFrame: 10 minutes before and 10 minutes after intervention protocol
Secondary outcomes:
Other outcomes:
Locations:
city: Castelló de la Plana
country: Spain
facility: University Jaume I
state: Castellón
Study officials:
affiliation: Universitat Jaume I
name: Maria Reyes Beltran Valls, PhD
role: PRINCIPAL_INVESTIGATOR
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citation: Brickenkamp, R., Schmidt-Atzert, L., & Liepmann, D. d2-R. Test de Atención - Revisado. TEA Ediciones. 2022.