louisbrulenaudet/clinical-trials huggingface dataset:
Clinical trial NCT06342791: Effect of Laser Acupuncture on Menstrual Back Pain
Official title: Effect of Laser Acupuncture on Menstrual Back Pain
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Laser Acupuncture
Low Back Pain
Menstruation
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2024-04-02
Enrollment: 32
Sex: FEMALE
Minimum age (years): 20
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: two groups
Primary purpose: TREATMENT

Brief summary: effect of laser acupuncture on menstrual back pain

Detailed description: The aim of this study is to determine the effect of laser acupuncture on the points BL23, BL26, BL40 and SP6 in relieving menstrual back pain.

Eligibility criteria: Inclusion Criteria:

* All females will have low back pain during menstruation
* Age of the patients will range from 20-30 years.
* Their BMI will be range from 20-30 kg/ m 2

Exclusion Criteria:

* - Psychiatric disorders
* Pelvic floor dysfunction
* Lumber disc prolapse or any Previous surgery on spine.
* Tumor in lumbar spine

Primary outcomes:
measure: back Pain intensity during menstruation
timeFrame: before 3 month from begining of treatment
measure: pain threshold
timeFrame: Before 3 month from begining of the treatment
measure: Ability to perform daily activities
timeFrame: Before 3 month from begining of the treatment
Secondary outcomes:
measure: back Pain intensity during menstruation
timeFrame: 3 month after treatment
measure: pain threshold
timeFrame: 3 month after treatment
measure: Ability to perform daily activities
timeFrame: 3 month after treatment
Other outcomes:
Locations:
city: Cairo
country: Egypt
facility: Faculty of physical therapy cairo university
Study officials:
affiliation: Faculty of physical therapy cairo universty
name: Cairo University
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT04309591: Cytosorb Therapy in Cardiac Surgery
Official title: Cytosorb Therapy in Cardiac Surgery - a Retrospective Study of Hemoadsorption in Patients With Endocarditis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Cardiopulmonary Surgery
Endocarditis
Peri-operative Cytokines Levels
Keywords: cytokine clearance
cardiac surgery
CytoSorb
cytokine removal
Lead sponsor: University Hospital, Basel, Switzerland
Sponsor class: OTHER
First posted: 2020-03-16
Enrollment: 249
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: RETROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: patients with endocarditis undergoing cardiac surgery with cardio-pulmonary bypass circuit at the University Hospital Basel

Brief summary: Cardiopulmonary surgery is associated with inflammatory responses that can lead to systemic inflammatory responses (SIRS), organ dysfunction (MOD) and death especially in patients with endocarditis. Cytokine removal might therefore improve outcomes of patients undergoing cardiac surgery. CytoSorb is a device designed to remove cytokine (IL-6, IL-10, TNFalpha) from the blood to reduce immune reactions. This trial investigates the use of CytoSorb during cardiac surgery in patients with endocarditis at the University Hospital Basel.


Eligibility criteria: Inclusion Criteria:

* patients with endocarditis undergoing cardiac surgery with cardio-pulmonary bypass circuit

Exclusion Criteria:

* denial of consent for data use

Primary outcomes:
measure: In-Hospital mortality
timeFrame: during hospital stay for cardiac surgery from admission until discharge (approximately 15 days)
Secondary outcomes:
measure: time in intensive care unit (days)
timeFrame: during hospital stay for cardiac surgery from admission until discharge (approximately 15 days)
measure: In-Hospital time (days)
timeFrame: hospital stay for cardiac surgery from admission until discharge (approximately 15 days)
Other outcomes:
Locations:
city: Basel
country: Switzerland
facility: Klinik für Herzchirurgie, Universitätsspital Basel
Study officials:
affiliation: Universitätsspital Basel, Herzchirurgie
name: David Santer, Dr. med
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01071694: QOLBET Quality Of Life in Patients With Early Relapsing-remitting Multiple Sclerosis Treated With BETaferon® in Korea
Official title: QOLBET Quality Of Life in Patients With Early Relapsing-remitting Multiple Sclerosis Treated With BETaferon® in Korea
Study type: OBSERVATIONAL
Overall status: WITHDRAWN
Conditions: Multiple Sclerosis, Relapsing-Remitting
Keywords: Multiple Sclerosis,
Relapsing-Remitting,
Interferon beta-1b,
Quality of life
Lead sponsor: Bayer
Sponsor class: INDUSTRY
First posted: 2010-02-19
Enrollment: 0
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: COHORT
Time perspective: PROSPECTIVE
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Tertiary hospital

Brief summary: This study is to describe the quality of life of Korean patients with early relapsing-remitting multiple sclerosis during the initial 1 year of treatment with Betaferon with several validated questionnaires.


Eligibility criteria: Inclusion Criteria:

* Relapsing-remitting MS (RRMS) patients within the first two years after diagnosis according to Poser or McDonald criteria, starting Betaferon treatment, including patients switching from other DMDs
* Patients who signed informed consent form

Exclusion Criteria:

* Age lower than 18

Primary outcomes:
measure: Quality of life evaluated by several validated questionnaire
timeFrame: Baseline, 3, 6, 9, 12 months (+/- 1 month)
Secondary outcomes:
measure: Information about safety of Betaferon in routine clinical use
timeFrame: Baseline, 3, 6, 9, 12 months (+/- 1 month)
Other outcomes:
Locations:
city: Many locations
country: Korea, Republic of
Study officials:
affiliation: Bayer
name: Bayer Study Director
role: STUDY_DIRECTOR
References:
Clinical trial NCT02111694: Influence of Bottle-Type on Infant Feeding Behaviors
Official title: Influence of Bottle-Type on Infant Feeding Behaviors
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Conventional Clear Bottle
Opaque Weighted Bottle
Keywords: infant
intake
satiation
mother
feeding practices
bottle feeding
formula feeding
maternal responsiveness
infant cues
Lead sponsor: Drexel University
Sponsor class: OTHER
First posted: 2014-04-11
Enrollment: 29
Sex: ALL
Maximum age (years): 6
Standard ages: CHILD
Accepts healthy volunteers: yes
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: PREVENTION

Brief summary: The objective of the proposed research is to conduct a within-subject, experimental study that will describe mothers' feeding practices during typical bottle-feeding conditions and will examine whether removal of visual cues related to the amount of milk/formula in the bottle will alter these feeding practices. The investigators hypothesize that mothers will show higher levels of infant-directed feeding practices and lower levels of mother-directed feeding practices when using opaque, weighted bottles compared to when using standard, clear bottles. The investigators also hypothesize that infants will consume less breast milk or formula when fed from opaque, weighted bottles compared to when fed from standard, clear bottles.


Eligibility criteria: Inclusion Criteria:

* Mothers must be 18 years or older
* Infants must be between 0- and 6-months of age
* Infants must be prior to the introduction of solid foods

Exclusion Criteria:

* Preterm birth
* Medical conditions that interfere with feeding

Primary outcomes:
measure: Infant intake within a feeding (mL)
timeFrame: 3-hour period
measure: Maternal responsiveness to infant cues during a feeding
timeFrame: 3-hour period
Secondary outcomes:
measure: Maternal perception/acceptance of the bottles during a feeding
timeFrame: 3-hour period
Other outcomes:
Locations:
city: Philadelphia
country: United States
facility: Drexel University
state: Pennsylvania
Study officials:
affiliation: Drexel University
name: Alison K Ventura, PhD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Ventura AK, Pollack Golen R. A pilot study comparing opaque, weighted bottles with conventional, clear bottles for infant feeding. Appetite. 2015 Feb;85:178-84. doi: 10.1016/j.appet.2014.11.028. Epub 2014 Nov 28.
citation: Golen RB, Ventura AK. Mindless feeding: Is maternal distraction during bottle-feeding associated with overfeeding? Appetite. 2015 Aug;91:385-92. doi: 10.1016/j.appet.2015.04.078. Epub 2015 May 4.
Clinical trial NCT06297694: Clinical Interpretation and Cutoff Scores for ABILHAND Questionnaire in Rheumatoid Arthritis
Official title: Clinical Interpretation and Cutoff Scores for Manual Ability Measured by the ABILHAND Questionnaire in Individuals With Rheumatoid Arthritis
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Rheumatoid Arthritis
Lead sponsor: Pamukkale University
Sponsor class: OTHER
First posted: 2024-03-07
Enrollment: 156
Sex: ALL
Minimum age (years): 20
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: PROBABILITY_SAMPLE
Study population: PAU Romatology clinic

Brief summary: In individuals with rheumatoid arthritis, the most significant symptom is the loss of manual ability and function in the hands. In rheumatoid arthritis, where patient-reported assessment scales are frequently used, hand skills should be evaluated with an ideal questionnaire that best represents hand activities. The ABILHAND-RA questionnaire possesses all these features, being a short and easily fillable survey. The aim is to determine of clinically significant cutoff scores for perceived manual ability evaluated by ABILHAND corresponding to observed and perceived upper extremity assessments in individuals with rheumatoid arthritis.


Eligibility criteria: Inclusion Criteria:

* People between the ages of 20-65, who were diagnosed with RA according to ACR criteria by the PAU Rheumatology clinic and who volunteered to participate in the study, will be included.

Exclusion Criteria:

* Patients with RA who have a neurological disease that may affect hand functions (peripheral nerve lesion, trauma, operation, cerebrovascular accident), a psychiatric disease that affects cooperation, heart failure and lung pathology that affect daily living activities, and those with other concurrent autoimmune and rheumatic diseases.

Primary outcomes:
measure: Disease Activity Score (DAS 28)
timeFrame: Baseline
measure: Nine hole peg test
timeFrame: Baseline
measure: Hand grip strength
timeFrame: Baseline
Secondary outcomes:
Other outcomes:
Locations:
city: Denizli
country: Turkey
facility: Pamukkale University School of Physical Therapy and Rehabilitation
Study officials:
affiliation: Pamukkale University
name: Bilge Basakci Calik
role: STUDY_DIRECTOR
References:
Clinical trial NCT02249494: Mobile Application to Improve Nutritional Counseling Provided by Primary Care Physicians for Hypertension.
Official title: Nutritional Recommendations for Hypertension: Development of Mobile Application for Improve Knowledge in Lifestyle Modification for Primary Care Physicians
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Hypertension
Keywords: Nutritional Knowledge
Nutritional Counseling
Lead sponsor: Hospital de Clinicas de Porto Alegre
Sponsor class: OTHER
Collaborators: name: Federal University of Rio Grande do Sul
First posted: 2014-09-25
Enrollment: 110
Sex: ALL
Standard ages: CHILD
ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of this study is to investigate whether the use of a mobile app could improve knowledge and practice in nutrition counseling performed by primary care physicians in Brazil.

Detailed description: To optimize the nutritional care in the context of the limitations of available time and knowledge in medical practice, the present study proposes to develop a tool of nutritional guidelines for hypertension, easily accessible, based on evidence, and then evaluate its use among primary care physicians registered in a center telehealth. The use of the mobile application tool will aim to improve the nutritional counseling, helping with prevention of other chronic diseases in primary care context.

Eligibility criteria: Inclusion Criteria:

* primary care physicians registered in TelessaúdeRS (Center for Telehealth)
* primary care physicians who use smartphone or tablet

Exclusion Criteria:

* not to work in primary care

Primary outcomes:
measure: Change in score of knowledge and ability related to nutritional care.
timeFrame: 30 days
Secondary outcomes:
Other outcomes:
Locations:
city: Porto Alegre
country: Brazil
facility: Núcleo de Telessaúde Técnico-Científico do Rio Grande do Sul. Universidade Federal do Rio Grande do Sul
state: Rio Grande do Sul
Study officials:
affiliation: Federal University of Rio Grande do Sul
name: Erno Harzheim, doctor
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT01635894: A Community Intervention Study of Female Pelvic Floor Condition and Knowledge of Pelvic Floor Exercises
Official title: A Community Intervention Study of Female Pelvic Floor Condition and Knowledge of Pelvic Floor Exercises
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Behavioural
Keywords: female pelvic floor condition
pelvic floor training
supervised pelvic floor training
practice nurse
nurse specialist
Lead sponsor: University Hospital Plymouth NHS Trust
Sponsor class: OTHER
First posted: 2012-07-10
Enrollment: 240
Sex: FEMALE
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: HEALTH_SERVICES_RESEARCH

Brief summary: The aims of the study were to attempt to answer the following questions; what proportion of women know how to and are able to exercise their pelvic floor and for those who cannot can they be trained and motivated to do so. This was a nested design comprising a prospective cohort study together with a controlled trial intervention after baseline assessment in the cohort study for a defined at-risk group.


Eligibility criteria: Inclusion Criteria:

Able to give consent Aged above 18 years modified Oxford score, MOS, ≤ 2

Exclusion Criteria:

Unable to give consent

-

Primary outcomes:
measure: maximal vaginal squeeze pressure (perineometry).
timeFrame: monthly for 3 months
Secondary outcomes:
measure: endurance of contraction (perineometry)and digital vaginal palpation (MOS).
timeFrame: monthly for 3 months
Other outcomes:
Locations:
city: Plymouth
country: United Kingdom
facility: Plymouth Hospitals NHS Trust
state: Devon
Study officials:
affiliation: University Hospital Plymouth NHS Trust
name: Robert Freeman, MD
role: PRINCIPAL_INVESTIGATOR
References:
citation: Waterfield A, Waterfield M, Campbell J, Freeman R. Can effective supervised pelvic floor muscle training be provided by primary care nurses? A randomized controlled trial. Int Urogynecol J. 2021 Oct;32(10):2717-2725. doi: 10.1007/s00192-021-04692-3. Epub 2021 Feb 23.
Clinical trial NCT06852794: USE OF ARTIFICIAL INTELLIGENCE IN A PULMONARY FIBROSIS CLINIC
Official title: USE OF ARTIFICIAL INTELLIGENCE IN THE BACK-OFFICE OF A SPECIALIZED MEDICAL CLINIC FOR PULMONARY FIBROSIS (LLM-ILD)
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Interstitial Disease
Keywords: Artificial Intelligence
Lead sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sponsor class: OTHER
First posted: 2025-02-28
Enrollment: 100
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: OTHER

Brief summary: The present study aims to evaluate the usefulness of artificial intelligence (AI) in the back-office of an ILD (Interstitial Lung Disease) clinic.


Eligibility criteria: Inclusion Criteria:

- Patients attending ILD clinic of the IRCCS Fondazione Policlinico A. Gemelli.

Exclusion Criteria:

* Patients unable or unwilling to sign the informed consent
* Patients who are senders of one of the emails chosen for the questionnaire
* Patients with manifest inability to fill out the questionnaire

Primary outcomes:
measure: Variation of VAS scores of clarity of the message in questionnaires administered at T1 and at T2
timeFrame: 15 days
measure: Variation of VAS scores of empathy conveyed in questionnaires administered at T1 and at T2
timeFrame: 15 days
Secondary outcomes:
measure: Percentage of answers recognised correctly as answers provided by AI among the total of answers flagged as provided by AI by study subjects
timeFrame: 1 day
measure: Stratify the results by patients' demographic characteristics and past experiences with artificial intelligence systems.
timeFrame: 1 day
Other outcomes:
Locations:
Study officials:
References:
Clinical trial NCT04610294: Operating Room Air Filtration/Sterilization
Official title: Operating Room Air Filtration/Sterilization and Surgical Site Infection: A Randomized Multiple Cross-over Cluster Trial
Study type: INTERVENTIONAL
Overall status: ACTIVE_NOT_RECRUITING
Phase: NA
Conditions: Surgery
Lead sponsor: The Cleveland Clinic
Sponsor class: OTHER
First posted: 2020-10-30
Enrollment: 66273
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Randomized multiple crossover cluster trial
Primary purpose: PREVENTION

Brief summary: Determine whether operating room air filtration and sterilization with the ActivePure system reduces a composite of serious surgical site infections, infection-related complications, and death within 30 days after surgery.

Detailed description: The investigators primary goal is thus to determine whether supplemental filtering and sterilizing operating room air reduces a composite of serious surgical site infections, infection-related complications, and death within 30 days after surgery. The primary outcome will be restricted to inpatients. However, outpatients will be simultaneously enrolled given the trial's cluster design. Sample-size is based on our primary inpatient analysis, N= 66,273 inpatients. Available outpatients will be included for analysis of our secondary outcome which includes both inpatients and outpatients.

Eligibility criteria: Inclusion Criteria:

* All patients in designated adult operating rooms
* American Society of Anesthesiologists physical status 1-4.
* Surgery lasting at least 1 hour.

Primary outcomes:
measure: Serious surgical site infections and related complication in previously uninfected surgical inpatients
timeFrame: 30 days after surgery
Secondary outcomes:
measure: Serious surgical site infections and related complication in previously uninfected surgical inpatients and outpatients
timeFrame: 30 days after surgery
Other outcomes:
Locations:
city: Cleveland
country: United States
facility: Cleveland Clinic
state: Ohio
Study officials:
affiliation: The Cleveland Clinic
name: Daniel I Sessler, MD
role: PRINCIPAL_INVESTIGATOR
References:
Clinical trial NCT02016794: A Focused Registry on Anterior Cervical Interbody Spacer ACIS
Official title: A Focused Registry on Anterior Cervical Interbody Spacer Procedures in Patients With Cervical Spine Degeneration
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Degenerative Cervical Spine
Keywords: cervical
interbody
spacer
degenerative
pain
neck
decompression
fusion
implant
Lead sponsor: AO Innovation Translation Center
Sponsor class: OTHER
First posted: 2013-12-20
Enrollment: 9
Sex: ALL
Minimum age (years): 21
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Observational model: CASE_ONLY
Time perspective: PROSPECTIVE
Sampling method: PROBABILITY_SAMPLE
Study population: Patients undergoing surgery for degenerative cervical condition that requires anterior decompression and fusion in a single or multiple levels

Brief summary: Degenerative cervical spine conditions lead to chronic neck and arm pain. Surgical treatment may require anterior decompression and fusion, which usually is established with a cage implant. The Anterior Cervical Interbody Spacer (ACIS) is such a cage.


Eligibility criteria: Inclusion Criteria:

* Age 21 years or older
* Degenerative cervical condition that requires anterior decompression and fusion in a single or multiple levels
* Degenerative cervical disc disease C3 through Th1 or
* Ruptured and herniated discs C3 through Th1
* Ability to understand the content of the patient information / informed consent form
* Willingness and ability to participate in the registry according to the registry plan (RP)
* Signed and dated IRB / EC-approved written informed consent

Exclusion Criteria:

* Spinal tumor
* Osteoporosis
* Cervical trauma and instability
* Any not medically managed severe systemic disease (ie. infection)
* Recent history of substance abuse (ie, recreational drugs, alcohol) that would preclude reliable assessment
* Pregnancy or women planning to conceive within the registry period
* Prisoner
* Participation in any other medical device or medicinal product clinical investigation or registry within the previous month that could influence the results of the present registry

Intraoperative exclusion criteria:

* Intraoperative decision to use implants other than the device under investigation

Primary outcomes:
measure: Effect of neck pain on everyday life measured by the Neck Disability Index (NDI).
timeFrame: 6 months
Secondary outcomes:
measure: Pain
timeFrame: Baseline; 1-2days; 6 weeks; 6 months
measure: Handling details
timeFrame: Intraoperative
measure: Length of Hospital Stay
timeFrame: Expected average of 5 days
measure: Adverse Events
timeFrame: Intra and post operative
Other outcomes:
Locations:
city: Brasschaat
country: Belgium
facility: AZ Klina
city: Duffel
country: Belgium
facility: AZ Sint Maarten
Study officials:
References:
Clinical trial NCT02267694: Study of Freeze-dried Black Raspberry in Maintenance of Ulcerative Colitis
Official title: A Trial of Freeze-dried Black Raspberry in Maintenance of Remission of Ulcerative Colitis
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE1
Conditions: Ulcerative Colitis
Lead sponsor: UConn Health
Sponsor class: OTHER
Collaborators: name: Medical College of Wisconsin
First posted: 2014-10-17
Enrollment: 7
Sex: ALL
Minimum age (years): 18
Maximum age (years): 90
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: TREATMENT

Brief summary: This research study is about adding Black Raspberry powder to the treatment regimen of patients with ulcerative colitis who are currently in remission and doing well.


Eligibility criteria: Inclusion Criteria:

Adult patients (\>18 years of age) with known diagnosis of ulcerative colitis who are currently in remission on a stable dose of 5-ASA products and/or steroids (equivalent to prednisone 20 mg or less). English speaking/reading male or female patients from all ethnicities will be considered for the study.

Exclusion Criteria:

* Treatment with Immunomodulators and/or biologic agents, active disease flare, patients younger than 18 years old, patients who are pregnant or trying to get pregnant, breast feeding and those with reported history of allergy or hypersensitivity to berry products.

Patients who are using NSAIDS will also be excluded from the study but low dose ASA (81-162 mg) is permitted if needed.

Primary outcomes:
measure: Remission rate
timeFrame: 6 months
Secondary outcomes:
Other outcomes:
Locations:
city: Farmington
country: United States
facility: University of Connecticut Health Center
state: Connecticut
Study officials:
affiliation: UConn Health
name: Haleh Vaziri, MD
role: PRINCIPAL_INVESTIGATOR
References: