Clinical trial NCT06131827: Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.
Official title: Combined Effects of Neural Mobilization With Task Based Activities on Spasticity and Motor Function of Upper Limb in Patients With Chronic Stroke.
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Chronic Stroke
Keywords: Neural mobilization
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-11-14
Enrollment: 34
Sex: ALL
Minimum age (years): 30
Maximum age (years): 55
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb dysfunction. In this study we use two techniques to improve upper limb motor dysfunction and reduce spasticity. One is task-based activities which is used to improve motor function and focus on active participation rather than normal movement pattern and other is neural mobilization which aims to reduce spasticity which is most common in stroke patients.

Detailed description: This study will be randomized controlled trial. Participants having stroke past 6 month to 1 year and mini mental state examination score \>21 will be included in this study. And participants with severe orthopedic deformity, joint pain and visual impairment will be excluded from this study. The sample size will consist of 34 participants selected through non probability convenient sampling technique, which will further be randomized through sealed envelope method and will divide into two groups .Data will be collected using assessment tools, including the Fugl Mayer assessment scale, box and block test and wolf motor function test. 17 Participants will be assigned to the interventional group (A )which will undergo neural mobilization of median nerve with task based activities .Neural mobilization technique will be performed with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 week.

while task based activities will be performed with the dosage of 45 minutes session 5 days weekly for 6 weeks and 17 participants will be assigned to control group (B

)which will undergo only neural mobilization of median nerve and will receive neural mobilization with twenty oscillations per minute being repeated three sets of one minute respecting one minute interval for rest between each set for 4 days weekly for 6 weeks. After applying both interventions motor function improvement and spasticity reduction will be measured by using BBT, wolf motor scale and fugl -Meyer assessment scale and data will be analyzed through sPss Version 25.

Eligibility criteria: Inclusion Criteria:

* Male and female stroke patients.
* 6 month to one year post stroke .
* Age 30-55
* Stable patients
* Mini - mental state examination\>2
* Modified ashworth Scale equal\<+1

Exclusion Criteria:

* Orthopedic deformity
* Patients undergo bottulinuminjection toxin injection
* Visual impairments
* Joint pain (elbow, shoulder, wrist)

Primary outcomes:
measure: Box and block test
timeFrame: 6 weeks
measure: Wolf motor Function Test
timeFrame: 6 weeks
measure: Fugl -Meyer assessment scale
timeFrame: 6 weeks
Secondary outcomes:
Other outcomes:
Locations:
city: Lahore
country: Pakistan
facility: Ripha international university
state: Punjab
Study officials:
affiliation: Ripha international university
name: Memona Ayesha, Ms-NMPT
role: PRINCIPAL_INVESTIGATOR
References: