Clinical trial NCT00579267: Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
Official title: Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
Study type: OBSERVATIONAL
Overall status: COMPLETED
Conditions: Major Depression
Mania
Anxiety Disorders
Psychotic Disorder
Alcohol Dependence
Drug Dependence
Eating Disorders
Suicidality
Dysthymia
ADHD
Tourettes Disorder
Conduct Disorder
Oppositional Defiant Disorder
Pervasive Developmental Disorder
Keywords: MINI-KID
structured diagnostic interview
reliability and validity
K-SADS
Sheehan Disability Scale
Lead sponsor: University of South Florida
Sponsor class: OTHER
First posted: 2007-12-24
Enrollment: 230
Sex: ALL
Minimum age (years): 6
Maximum age (years): 17
Standard ages: CHILD
Accepts healthy volunteers: yes
Observational model: CASE_ONLY
Time perspective: CROSS_SECTIONAL
Sampling method: NON_PROBABILITY_SAMPLE
Study population: Children and adolescents between the ages of 6 and 18 years.

Brief summary: The primary aims of this study are to assess:

1. The inter-rater and test-retest reliability of the MINI-KID
2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and th longer clinician rated "Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) and "expert opinion" (when available).

Secondary aims will include evaluating the concordance between: The Children's Global Assessment Scale (a required part of the K-SADS) with the clinician-rated Sheehan Disability Scale (to be administered with the MINI-KID) as a measure of illness severity.

Detailed description: The MINI-KID is a short, structured diagnostic interview used to assess the presence of 24 DSM-IV child and adolescent psychiatric disorders as well as the risk of suicide.

To achieve adequate representation of the major psychiatric disorders and sufficient normal controls, we propose recruiting 230 children and adolescents (ages 6 to 17 years 11 months), comprised of 200 subjects identified as having one or more psychiatric disorders and 30 normal controls in the community. These subjects will be from diverse socioeconomic, racial and ethnic backgrounds. We will assess the inter-rater and test-retest reliability of the MINI-KID and examine its validity with the "gold-standard" diagnostic interview for children and adolescents as well as expert opinion.

Eligibility criteria: Inclusion Criteria:

* Subjects will be between the ages of 6 years and 17 years, 11 months
* All subjects must meet MINI-KID DSM-IV criteria for a least one of the Axis I child psychiatry disorders covered by the MINI-KID.
* Both sexes are included.

Exclusion Criteria:

* Subjects who suffer from mental retardation, significant developmental disorders, congenital abnormalities, delirium, dementia, a language problem, or brain damage will be excluded.
* Subjects with neurological disorders, chronic or life threatening diseases will be excluded.

Primary outcomes:
measure: Kappa scores between MINI Kid and K-SADS
timeFrame: 4 years
Secondary outcomes:
Other outcomes:
Locations:
city: Tampa
country: United States
facility: University of South Florida College of Medicine, Department of Psychiatry
state: Florida
Study officials:
affiliation: University of South Florida College of Medicine
name: David V. Sheehan, MD, MBA
role: PRINCIPAL_INVESTIGATOR
References:
citation: Sheehan DV, Sheehan KH, Shytle RD, Janavs J, Bannon Y, Rogers JE, Milo KM, Stock SL, Wilkinson B. Reliability and validity of the Mini International Neuropsychiatric Interview for Children and Adolescents (MINI-KID). J Clin Psychiatry. 2010 Mar;71(3):313-26. doi: 10.4088/JCP.09m05305whi.