Clinical trial NCT06086691: Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Official title: Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Muscle Damage
Keywords: Caffeine
Creatine Kinase
Endurance Training
Fitness Centers
Skeletal Muscle
Strength Training
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-10-17
Enrollment: 14
Sex: MALE
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: CROSSOVER
Intervention model description: Randomized Crossover Trial
Primary purpose: OTHER

Brief summary: Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars. Many of these products contain numerous ingredients in varied combinations and amounts. Among the more common ingredients are amino acids, protein, creatine, and caffeine

Detailed description: Caffeine is a popular nutritional supplement among gym athletes. It is frequently used as an ergogenic aid to improve physical performance, delay fatigue, and increase muscle power. This research aims to evaluate the effectiveness of caffeine through the blood sample test (Serum CK, LDH levels, AST levels) on muscle damage of gym athletes who are performing aerobic and strength training. This study would help understand the effects of strength training and endurance training on muscle damage in gym athletes who are consuming caffeine and to check the serum enzymes level of both groups who are on strength training and those who are on endurance level training, therefore, this study would help determine which athletes should be careful while consuming caffeine for a particular exercise regimen

Eligibility criteria: Inclusion Criteria:

* Male gym athletes
* Age: 18-40 years
* Athletes with at least three days training session per week

Exclusion Criteria:

* Athletes already on caffeine supplementation
* Athletes with above normal serum enzyme levels

Primary outcomes:
measure: Serum CK Levels
timeFrame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
measure: Serum LDH levels
timeFrame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
measure: Serum AST levels
timeFrame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
Secondary outcomes:
measure: Rating of fatigue scale/Numeric Rating Scale-Fatigue
timeFrame: Pre-intervention, after 24 hours of the intervention, after 3 days before second intervention, and after 24 hours of the second intervention
Other outcomes:
Locations:
city: Islamabad
country: Pakistan
facility: Riphah International University (RIU)
state: Islamabad Capital Territory
Study officials:
affiliation: Riphah International University, Islamabad.
name: Noman Sadiq, MS-SPT
role: PRINCIPAL_INVESTIGATOR
References: