Clinical trial NCT07002125: Whole Body Vibration Therapy in Individuals With Type 2 Diabetes
Official title: The Effect of Whole Body Vibration Therapy on Muscle Oxygenation in Individuals With Type 2 Diabetes: A Randomized Controlled Trial
Study type: INTERVENTIONAL
Overall status: NOT_YET_RECRUITING
Phase: NA
Conditions: Type 2 Diabetes
Whole Body Vibration
Muscle Oxygenation
Aerobic Exercise
Keywords: Aerobic exercise
diapason
balance
HbA1c
type 2 diabetes
whole body vibration
muscle oxygenation
Lead sponsor: Ankara Medipol University
Sponsor class: OTHER
Collaborators: name: Gazi University
First posted: 2025-06-03
Enrollment: 20
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Individuals with Type 2 diabetes who agreed to participate in the study will be divided into two groups as aerobic exercise group (AE) and whole body vibration group (AE+WBV).
Primary purpose: TREATMENT

Brief summary: The aim of this interventional study is to investigate the effect of whole body vibration therapy on muscle oxygenation, vibration sensation, functional capacity and balance in individuals with Type 2 diabetes.

The main questions aimed to be answered are:

* Does whole body vibration therapy affect peripheral muscle oxygenation?
* Does whole body vibration therapy improve vibration sense, functional capacity and balance compared to aerobic exercise? Participants' muscle oxygenation, vibration sensation, functional capacity and balance parameters will be assessed. They will participate in a whole body vibration therapy or aerobic training program.


Eligibility criteria: Inclusion Criteria:

* Volunteering to participate in the research
* Being diagnosed with type 2 diabetes
* 18 years of age or older
* HbA1c level to be 6.5-10%
* Having a clinical history of diabetes between 2-10 years
* Receiving oral hypoglycemic agent treatment
* At least three HbA1c measurements within 12 to 24 months
* Hemoglobin variability score (HVS) \<50
* Being able to walk independently
* Mini mental test score ≥ 24
* Vastus lateralis muscle adipose tissue thickness \<20mm
* BMI \<30 kg/m2

Exclusion Criteria:

* Previous or concurrent psychiatric, neurological, orthopedic or systemic illness
* Use of insulin in treatment
* Diabetic neuropathy
* Foot ulcer
* Participation in any exercise program in the last 6 months
* History of major hypoglycemia in the last 12 months
* Working or have worked in a job with high exposure to mechanical whole body vibrations
* Conditions that may contraindicate whole body vibration (deep vein thrombosis, severe osteoporosis, active cancer, implanted medical devices, etc.)
* Hearing, vision and perception problems that may affect research results

Primary outcomes:
measure: Muscle Oxygenation
timeFrame: 8 weeks
Secondary outcomes:
measure: Vibration sense
timeFrame: 8 weeks
measure: The Timed Up & Go Test
timeFrame: 8 weeks
measure: The 6 minute walk test
timeFrame: 8 weeks
measure: The 30-second Chair Stand Test
timeFrame: 8 weeks
measure: Balance
timeFrame: 8 weeks
Other outcomes:
Locations:
city: Ankara
country: Turkey
facility: Gazi University, Faculty of Health, Department of Physiotherapy and Rehabilitation
state: Çankaya
Study officials:
References: