Clinical trial NCT05619874: Effects of Two Virtual HIFCT Programs in Adults With Abdominal Obesity
Official title: Effects of Two Virtual High-intensity Functional Circuit Training Programs on Intra-abdominal Fat, Body Composition, Health-related Quality of Life, and Some Components of Physical Fitness in Adults With Abdominal Obesity
Study type: INTERVENTIONAL
Overall status: TERMINATED
Phase: NA
Conditions: Healthy Volunteers
Keywords: High-intensity functional circuit training
Virtual exercise
Obesity
Intra-abdominal fat
Waist circumference
Body composition
Lead sponsor: Universidad de Antioquia
Sponsor class: OTHER
First posted: 2022-11-17
Enrollment: 12
Sex: ALL
Minimum age (years): 18
Maximum age (years): 40
Standard ages: ADULT
Accepts healthy volunteers: yes
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: It is estimated that by 2030 one in five women and one in seven men will be obese, equivalent to more than 1 billion people around the world. It should be noted that the largest number of people with obesity live in countries with low and moderate-income. In 2019, more than 160 million years of healthy life were lost in the world, due to a high body mass index (BMI), this represents more than 20% of all years of healthy life lost due to chronic diseases. Therefore, it is essential to stop the increase in obesity and reduce it at all ages, which demands comprehensive actions at the global level. Scientific evidence suggests that people with a normal BMI, but with abdominal obesity, have a higher mortality risk compared to those with a similar or even higher BMI. In addition, visceral adiposity has been associated with worse survival and with colorectal cancer.

Several methods of physical exercise have been used to counteract the adverse effects of obesity, including high-intensity functional circuit training (HIFCT). Scientific evidence indicates that HIFCT reduces fat mass, body mass, BMI, and waist circumference and improves muscle strength, maximal oxygen uptake, and health-related quality of life in overweight, obese, inactive, and with other diseases. However, no research assessed intra-abdominal fat (IAF), which, more than subcutaneous fat, is associated with cardiovascular risk factors. In addition, these studies had important methodological limitations. Therefore, the primary purpose of this study is to identify the effect of two HIFCT protocols, prolonged load (HIFCT-P) and short load (HIFCT-S), performed in a virtual environment for ten weeks on intra-abdominal fat in people between 18-40 years-old with abdominal obesity.

Detailed description: A randomized controlled trial with parallel arms (HIFCT-P and HIFCT-C) based on a non-inferiority hypothesis comparing two proportions. Each participant will carry out 30 sessions, three times a week, in a virtual environment. General, concentrated, and block circuits will be used, with the same exercises, but with different load distribution and different order between them. Both HIFCT-P and HIFCT-S will carry out six initial adaptation sessions through a general circuit composed of 12 exercises. Different muscle groups will be alternated. The exercises will be performed at speeds between 35 and 55 beats per minute (bpm), to ensure intensities between 50% - 60% in sessions 1 to 3, and between 70% - 80% in sessions 4 to 6. The Modified Borg Rating of Perceived Exertion Scale (RPE) will be used to control intensities. From session seven to session 30, HIFCT-P and HIFCT-S will perform the same exercises but with a different load distribution.

Eligibility criteria: Inclusion Criteria:

* Healthy women and men.
* Physical activity (\<600 to ≤1500 MET/min/wk).
* Waist circumference (≥87cm).

Exclusion Criteria:

* Have performed high intensity exercises or HIFCT in the last two months.
* Smoking.
* History of cardiovascular disease.
* History of coronary heart disease.
* Pregnancy.
* Breast-feeding women.
* Psychological, neuromotor, and/or osteo-muscular conditions that may affect participation in an exercise program.

Primary outcomes:
measure: Change in intra-abdominal fat
timeFrame: Baseline and 10-weeks
Secondary outcomes:
measure: Change in waist circumference
timeFrame: Baseline and 10-weeks
Other outcomes:
measure: Fat mass, fat-free mass, whole-body and segmental skeletal muscle mass.
timeFrame: Baseline and 10-weeks
Locations:
city: Bogotá
country: Colombia
facility: Centro de Formación en Actividad Física y Cultura-SENA Distrito Capital
state: Cundinamarca
Study officials:
References: