Clinical trial NCT04656457: RESISTANCE VERSUS AEROBIC EXERCISES ON Breast Cancer Patients
Official title: Resistance Versus Aerobic Exercises On Cancer Related Fatigue And Immunity In Breast Cancer Patients Undergoing Adjuvant Chemotherapy
Study type: INTERVENTIONAL
Overall status: UNKNOWN
Phase: NA
Conditions: Breast Cancer
Lead sponsor: Cairo University
Sponsor class: OTHER
First posted: 2020-12-07
Enrollment: 60
Sex: FEMALE
Minimum age (years): 30
Maximum age (years): 60
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of the study is to evaluate which is more effective resistance or aerobic exercises on cancer related fatigue and immunity in breast cancer patients undergoing adjuvant chemotherapy.

Detailed description: The problem of cancer related fatigue and decreased immunity, as a result of treatment with adjuvant chemotherapy in breast cancer patients is not well known.

Fatigue and decreased immunity have a negative impact on work, social relationships, mood, and daily activities and cause significant impairment in overall quality of life, Furthermore the need of this study is developed from the lack of information in the published studies about the effect of the treatment with chemotherapy among breast cancer patients on inducing fatigue and decreasing immunity and the effect of resistance and aerobic exercises on improving these changes.

Eligibility criteria: Inclusion Criteria:

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The subject selection will be according to the following criteria:

1. Age range from 30-60 years.
2. Females post mastectomy only will participate in the study.
3. All patients undergoing adjuvant chemotherapy and have cancer related fatigue and decreased immunity.
4. All patients enrolled to the study will have their informed consent.

Exclusion Criteria:

* The potential participants will be excluded if they meet one of the following criteria:

  1. Age more than 60 years or less than 30 years.
  2. Another concurrent malignant disease.
  3. Subjects suffering from any condition for which resistance or aerobic exercises contraindicated as metastasis, sever osteoporosis and cardiac diseases.

Primary outcomes:
measure: Fatigue assessment scale
timeFrame: The evaluation will be conducted during before the cycles
measure: Fatigue assessment scale
timeFrame: The evaluation will be conducted during one and half month
measure: Fatigue assessment scale
timeFrame: The evaluation will be conducted three months later
measure: Hemoglobin level test for fatigue assessment
timeFrame: he evaluation will be conducted before the cycles
measure: Hemoglobin level test for fatigue assessment
timeFrame: he evaluation will be conducted during one and half month
measure: Hemoglobin level test for fatigue assessment
timeFrame: he evaluation will be conducted three months later
measure: White blood cells count test for immunity assessment
timeFrame: he evaluation will be conducted before the cycles
measure: White blood cells count test for immunity assessment
timeFrame: he evaluation will be conducted during one and half month
measure: White blood cells count test for immunity assessment
timeFrame: he evaluation will be conducted three months later
Secondary outcomes:
Other outcomes:
Locations:
city: Alexandria
country: Egypt
facility: Medical research institute
Study officials:
affiliation: faculty of physical therapy
name: Amal mo abdel baky, professor
role: STUDY_DIRECTOR
References: