Clinical trial NCT06565325: The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues
Official title: The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues on Vastus Medialis Muscle Motor Unit Behavior in Healthy Individuals
Study type: INTERVENTIONAL
Overall status: RECRUITING
Phase: NA
Conditions: Muscle Weakness
Keywords: Terminal Knee Extension Exercise
Audible Cues
Therapeutic exercise
Muscle strength
Lead sponsor: Mahidol University
Sponsor class: OTHER
First posted: 2024-08-21
Enrollment: 30
Sex: ALL
Minimum age (years): 18
Maximum age (years): 30
Standard ages: ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: There are 2 groups in the current study including exercise with and without audible cues.
Primary purpose: TREATMENT

Brief summary: Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome. Therefore, an increased effectiveness of TKE is interesting for physical therapy implication. Besides, adding sensory input which is audible cues or rhythm during exercise may enhance the efficacy of the exercise by increasing neuromuscular control and function.

Therefore, the study aimed to investigate the immediate effects of combined TKE with audible cues on motor unit behavior. The researchers expect that adding rhythm from the metronome will enhance neuromuscular control which may change motor unit behavior of VM muscle. The findings of the study may have helped explain the mechanism behind the acute effects of combined TKE with audible cues on VM function and their potential application in the field of physical therapy.

This study aims to investigate the immediate effect of combined TKE with audible cues on motor unit behavior in healthy participants and to investigate reliability of decomposition electromyography procedure during single leg squat.

Detailed description: A metronome will be used to provide rhythmic exercise. Participants will stand with their feet in line with their shoulders as starting position and straping at the knee. Exercise intensity is 60% of the 1RM weight. At the beginning of the exercise, participants will be asked to bend their knees following the pull of the resistance and exert force to straighten the knee (10 times/set and 3 sets). 180 seconds of resting will be allowed between sets.

Eligibility criteria: Inclusion Criteria:

* Aged range between 18 and 30 years
* BMI of 18.5-25 kg/m2
* Male or female
* Lightly active or sedentary {Physical activity level (PAL= 1.4-1.69)}

Exclusion Criteria:

* History of serious injury or operation of lower back and lower extremities such as fracture
* Musculoskeletal problems of lower back and lower extremities in 6 months before the study
* Single-leg stance test \< 43 seconds (26). and range of weight-bearing lunge test \< 9.1 cm

Primary outcomes:
measure: Motor unit firing rate
timeFrame: At the end of Cycle 1 (each cycle is 1 day)
measure: Peak motor action potential
timeFrame: At the end of Cycle 1 (each cycle is 1 day)
Secondary outcomes:
Other outcomes:
Locations:
city: Nakhon Pathom
country: Thailand
facility: Faculty of Physical Therapy, Mahidol University
state: Salaya
Study officials:
References: