Clinical trial NCT05629962: SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19
Official title: A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: PHASE3
Conditions: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2 Infection)
COVID-19
Lead sponsor: Atea Pharmaceuticals, Inc.
Sponsor class: INDUSTRY
First posted: 2022-11-29
Enrollment: 2285
Sex: ALL
Minimum age (years): 18
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Primary purpose: TREATMENT

Brief summary: The purpose of the study is to evaluate whether bemnifosbuvir (BEM) is effective and safe in adults with COVID-19 who do not need to be in the hospital but who are at high risk for progression to severe disease. Eligible subjects will be randomly assigned (by chance) to receive BEM or matching placebo orally for 5 days. Co-administration of locally available standard of care (SOC) is allowed. The total duration of the study is 60 days.


Eligibility criteria: Inclusion Criteria:

* Positive SARS-CoV-2 test conducted ≤ 5 days prior to randomization
* Mild or moderate COVID-19 with symptom onset ≤ 5 days before randomization and at least one COVID-19 related symptom present at time of screening
* Subject must be high risk, defined below:

  1. Age ≥70 years OR
  2. Age ≥55 years with one of the following: i) obesity (body mass index \[BMI\] ≥30 kg/m2) ii) diabetes mellitus iii) cardiovascular disease or hypertension iv) chronic lung disease requiring routine therapy OR
  3. Age 50 to 54 years with two of the following: i) obesity (BMI ≥30 kg/m2) ii) diabetes mellitus iii) cardiovascular disease or hypertension iv) chronic lung disease requiring routine therapy OR
  4. Age ≥18 years with one of the following: i) Down syndrome, sickle cell disease, dementia, Parkinson's disease, or care home residents ii) One of the following immunocompromising conditions or immunosuppressive treatments: receiving chemotherapy for cancer, hematologic malignancy, being within 2 years of a hematopoietic stem cell transplant, receipt of a solid organ transplant and on immunosuppressive therapy, human immunodeficiency virus (HIV) infection untreated or with CD4+ T lymphocyte count \<350 cells per cubic millimeter, moderate/severe primary immunodeficiency, taking immunosuppressive medications
* Use of adequate contraception for females of childbearing potential

Exclusion Criteria:

* Severe or critical COVID-19 illness
* Admitted to a hospital within 90 days prior to randomization due to COVID-19
* Use of other investigational drugs within 30 days prior to planned dosing, or plans to enroll in another clinical trial of an investigational agent while participating in the present study
* Initiation or planned initiation of remdesivir for treatment of the current SARS-CoV-2 infection
* Requirement of prohibited medications, including hydroxychloroquine or amiodarone within 3 months prior to screening. Note: Subjects who had already initiated any COVID-19 drug with antiviral effects intended to treat symptomatic SARS-CoV-2 infection (≥ 24 hours prior to randomization) will be excluded. During screening (or within 24 hours prior to or after randomization), locally available COVID-19 drugs with antiviral effects (including but not limited to nirmatrelvir/ritonavir, molnupiravir, favipiravir, monoclonal antibodies) will be permitted.
* Other known active viral or bacterial infection at the time of screening, such as influenza and respiratory syncytial virus (RSV). Note: This exclusion does not apply to subjects with stable chronic viral infections, such as chronic hepatitis C virus (HCV) or HIV providing other eligibility criteria are met.
* Receiving dialysis or have known severe renal impairment
* History of severe hepatic impairment (Child-Pugh Class C)
* Known allergy or hypersensitivity to components of study drug

Primary outcomes:
measure: Percentage of Subjects Hospitalized for Any Cause or Died Due to Any Cause
timeFrame: Day 1 through Day 29
Secondary outcomes:
measure: Percentage of Subjects Hospitalized Due to COVID-19 or Died Due to Any Cause
timeFrame: Day 1 through Day 29
measure: Percentage of Subjects Who Died Due to Any Cause
timeFrame: Day 1 through Day 29; Day 1 through Day 60
measure: Percentage of Subjects With COVID-19-related Complications
timeFrame: Day 1 through Day 29
measure: Percentage of Subjects With COVID-19-medically Attended Visits (Hospitalization, Emergency Room (ER) Visit, Urgent Care Visit, Physician's Office Visit, or Telemedicine Visit) or Who Died Due to Any Cause
timeFrame: Day 1 through Day 29; Day 1 through Day 60
measure: Percentage of Subjects With COVID-19 Symptom Relapse
timeFrame: Day 1 through Day 29
measure: Percentage of Subjects With Viral Load Rebound
timeFrame: Day 1 through Day 29
Other outcomes:
Locations:
city: Kingman
country: United States
facility: Atea Study Site
state: Arizona
city: Prescott
country: United States
facility: Atea Study Site
state: Arizona
city: Surprise
country: United States
facility: Atea Study Site
state: Arizona
city: Tucson
country: United States
facility: Atea Study Site
state: Arizona
city: Canoga Park
country: United States
facility: Atea Study Site
state: California
city: Fullerton
country: United States
facility: Atea Study Site
state: California
city: Inglewood
country: United States
facility: Atea Study Site
state: California
city: La Palma
country: United States
facility: Atea Study Site
state: California
city: Long Beach
country: United States
facility: Atea Study Site
state: California
city: Long Beach
country: United States
facility: Atea Study Site
state: California
city: Los Angeles
country: United States
facility: Atea Study Site
state: California
city: Sacramento
country: United States
facility: Atea Study Site
state: California
city: San Diego
country: United States
facility: Atea Study Site
state: California
city: Coral Gables
country: United States
facility: Atea Study Site
state: Florida
city: Cutler Bay
country: United States
facility: Atea Study Site
state: Florida
city: Doral
country: United States
facility: Atea Study Site
state: Florida
city: Hialeah
country: United States
facility: Atea Study Site
state: Florida
city: Miami Gardens
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: Miami
country: United States
facility: Atea Study Site
state: Florida
city: North Miami Beach
country: United States
facility: Atea Study Site
state: Florida
city: North Miami Beach
country: United States
facility: Atea Study Site
state: Florida
city: Pembroke Pines
country: United States
facility: Atea Study Site
state: Florida
city: Pompano Beach
country: United States
facility: Atea Study Site
state: Florida
city: Tampa
country: United States
facility: Atea Study Site
state: Florida
city: Tampa
country: United States
facility: Atea Study Site
state: Florida
city: Tampa
country: United States
facility: Atea Study Site
state: Florida
city: Tampa
country: United States
facility: Atea Study Site
state: Florida
city: The Villages
country: United States
facility: Atea Study Site
state: Florida
city: W. Miami
country: United States
facility: Atea Study Site
state: Florida
city: West Palm Beach
country: United States
facility: Atea Study Site
state: Florida
city: Eatonton
country: United States
facility: Atea Study Site
state: Georgia
city: Orland Park
country: United States
facility: Atea Study Site
state: Illinois
city: La Vista
country: United States
facility: Atea Study Site
state: Nebraska
city: Bronx
country: United States
facility: Atea Study Site
state: New York
city: Bronx
country: United States
facility: Atea Study Site
state: New York
city: Chapel Hill
country: United States
facility: Atea Study Site
state: North Carolina
city: High Point
country: United States
facility: Atea Study Site
state: North Carolina
city: Chickasha
country: United States
facility: Atea Study Site
state: Oklahoma
city: Providence
country: United States
facility: Atea Study Site
state: Rhode Island
city: Greenville
country: United States
facility: Atea Study Site
state: South Carolina
city: Rock Hill
country: United States
facility: Atea Study Site
state: South Carolina
city: Carrollton
country: United States
facility: Atea Study Site
state: Texas
city: Dallas
country: United States
facility: Atea Study Site
state: Texas
city: DeSoto
country: United States
facility: Atea Study Site
state: Texas
city: Forney
country: United States
facility: Atea Study Site
state: Texas
city: Fort Worth
country: United States
facility: Atea Study Site
state: Texas
city: Harlingen
country: United States
facility: Atea Study Site
state: Texas
city: Houston
country: United States
facility: Atea Study Site
state: Texas
city: Kingwood
country: United States
facility: Atea Study Site
state: Texas
city: Lewisville
country: United States
facility: Atea Study Site
state: Texas
city: Mesquite
country: United States
facility: Atea Study Site
state: Texas
city: San Antonio
country: United States
facility: Atea Study Site
state: Texas
city: Splendora
country: United States
facility: Atea Study Site
state: Texas
city: Stafford
country: United States
facility: Atea Study Site
state: Texas
city: Sugar Land
country: United States
facility: Atea Study Site
state: Texas
city: Bahía Blanca
country: Argentina
facility: Atea Study Site
state: Buenos Aires
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Atea Study Site
state: Buenos Aires
city: Mar Del Plata
country: Argentina
facility: Atea Study Site
state: Buenos Aires
city: Mar Del Plata
country: Argentina
facility: Atea Study Site
state: Buenos Aires
city: Ramos Mejía
country: Argentina
facility: Atea Study Site
state: Buenos Aires
city: San Nicolas
country: Argentina
facility: Atea Study Site
state: Buenos Aires
city: Buenos Aires
country: Argentina
facility: Atea Study Site
state: Ciudad Autonoma Buenos Aires
city: Córdoba
country: Argentina
facility: Atea Study Site
state: Cordoba
city: Rosario
country: Argentina
facility: Atea Study Site
state: Santa Fe
city: Rosario
country: Argentina
facility: Atea Study Site
state: Santa Fe
city: San Miguel De Tucumán
country: Argentina
facility: Atea Study Site
state: Tucuman
city: San Miguel De Tucumán
country: Argentina
facility: Atea Study Site
state: Tucuman
city: Ciudad Autonoma de Buenos Aire
country: Argentina
facility: Atea Study Site
city: Córdoba
country: Argentina
facility: Atea Study Site
city: Santiago Del Estero
country: Argentina
facility: Atea Study Site
city: Maceió
country: Brazil
facility: Atea Study Site
state: Alagoas
city: Salvador
country: Brazil
facility: Atea Study Site
state: Bahia
city: Salvador
country: Brazil
facility: Atea Study Site
state: Bahia
city: Fortaleza
country: Brazil
facility: Atea Study Site
state: Ceara
city: Fortaleza
country: Brazil
facility: Atea Study Site
state: Ceara
city: Brasília
country: Brazil
facility: Atea Study Site
state: Distrito Federal
city: Cachoeiro De Itapemirim
country: Brazil
facility: Atea Study Site
state: Espirito Santo
city: Serra
country: Brazil
facility: Atea Study Site
state: Espirito Santo
city: Vitória
country: Brazil
facility: Atea Study Site
state: Espirito Santo
city: Cuiabá
country: Brazil
facility: Atea Study Site
state: Mato Grosso
city: Belo Horizonte
country: Brazil
facility: Atea Study Site
state: Minas Gerais
city: Belo Horizonte
country: Brazil
facility: Atea Study Site
state: Minas Gerais
city: Belo Horizonte
country: Brazil
facility: Atea Study Site
state: Minas Gerais
city: Campina Grande Do Sul
country: Brazil
facility: Atea Study Site
state: Parana
city: Rio De Janeiro
country: Brazil
facility: Atea Study Site
state: Rio Do Janeiro
city: Natal
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Norte
city: Natal
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Norte
city: Passo Fundo
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Sul
city: Porto Alegre
country: Brazil
facility: Atea Study Site
state: Rio Grande Do Sul
city: Porto Velho
country: Brazil
facility: Atea Study Site
state: Rondonia
city: Blumenau
country: Brazil
facility: Atea Study Site
state: Santa Catarina
city: Florianópolis
country: Brazil
facility: Atea Study Site
state: Santa Catarina
city: Itajaí
country: Brazil
facility: Atea Study Site
state: Santa Catarina
city: Itajaí
country: Brazil
facility: Atea Study Site
state: Santa Catarina
city: Joinville
country: Brazil
facility: Atea Study Site
state: Santa Catarina
city: Barretos
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Bento Gonçalves
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Botucatu
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Campinas
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Ijuí
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Jaú
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Osasco
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Ribeirão Preto
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Santa Catarina
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: São José Do Rio Preto
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: São Paulo
country: Brazil
facility: Atea Study Site
state: Sao Paulo
city: Valinhos
country: Brazil
facility: Atea Study Site
state: São Paulo
city: Rio De Janeiro
country: Brazil
facility: Atea Study Site
city: Edmonton
country: Canada
facility: Atea Study Site
state: Alberta
city: Chicoutimi
country: Canada
facility: Atea Study Site
state: Quebec
city: Muenchen
country: Germany
facility: Atea Study Site
state: Bayern
city: Frankfurt am Main
country: Germany
facility: Atea Study Site
state: Hessen
city: Berlin
country: Germany
facility: Atea Study Site
city: Hamburg
country: Germany
facility: Atea Study Site
city: Hyderabad
country: India
facility: Atea Study Site
state: Andhra Pradesh
city: Nellore
country: India
facility: Atea Study Site
state: Andhra Pradesh
city: Visakhapatnam
country: India
facility: Atea Study Site
state: Andhra Pradesh
city: Nellore
country: India
facility: Atea Study Site
state: Andhra Prasesh
city: New Delhi
country: India
facility: Atea Study Site
state: Delhi
city: Ahmedabad
country: India
facility: Atea Study Site
state: Gujarat
city: Gotri
country: India
facility: Atea Study Site
state: Gujarat
city: Sūrat
country: India
facility: Atea Study Site
state: Gujarat
city: Sūrat
country: India
facility: Atea Study Site
state: Gujarat
city: Faridabad
country: India
facility: Atea Study Site
state: Haryana
city: Bangalore
country: India
facility: Atea Study Site
state: Karnataka
city: Bangalore
country: India
facility: Atea Study Site
state: Karnataka
city: Bangalore
country: India
facility: Atea Study Site
state: Karnataka
city: Bengaluru
country: India
facility: Atea Study Site
state: Karnataka
city: Dombivli
country: India
facility: Atea Study Site
state: Maharashtra
city: Nashik
country: India
facility: Atea Study Site
state: Maharashtra
city: Nashik
country: India
facility: Atea Study Site
state: Maharashtra
city: Pune
country: India
facility: Atea Study Site
state: Maharashtra
city: Jaipur
country: India
facility: Atea Study Site
state: Rajasthan
city: Jaipur
country: India
facility: Atea Study Site
state: Rajasthan
city: Chennai
country: India
facility: Atea Study Site
state: Tamilnadu
city: Fukuoka
country: Japan
facility: Atea Study Site
state: Fukuoka City
city: Fukuoka-Shi
country: Japan
facility: Atea Study Site
state: Fukuoka-Ken
city: Kitakyushu
country: Japan
facility: Atea Study Site
state: Fukuoka-Ken
city: Kasuga
country: Japan
facility: Atea Study Site
state: Fukuoka
city: Sapporo
country: Japan
facility: Atea Study Site
state: Hokkaido
city: Himeji
country: Japan
facility: Atea Study Site
state: Hyogo
city: Tsuchiura
country: Japan
facility: Atea Study Site
state: Ibaraki
city: Kanazawa
country: Japan
facility: Atea Study Site
state: Ishikawa
city: Fujisawa
country: Japan
facility: Atea Study Site
state: Kanagawa
city: Kamakura
country: Japan
facility: Atea Study Site
state: Kanagawa
city: Izumisano
country: Japan
facility: Atea Study Site
state: Osaka
city: Toda
country: Japan
facility: Atea Study Site
state: Saitama
city: Uozu
country: Japan
facility: Atea Study Site
state: Toyama
city: Chiba
country: Japan
facility: Atea Study Site
city: Fukuoka
country: Japan
facility: Atea Study Site
city: Okayama
country: Japan
facility: Atea Study Site
city: Daugavpils
country: Latvia
facility: Atea Study Site
city: Riga
country: Latvia
facility: Atea Study Site
city: Saltillo
country: Mexico
facility: Atea Study Site
state: Coahuila
city: Torreon
country: Mexico
facility: Atea Study Site
state: Coahuila
city: Mexico
country: Mexico
facility: Atea Study Site
state: Distrito Federal
city: Guadalajara
country: Mexico
facility: Atea Study Site
state: Jalisco
city: Ciudad de mexico
country: Mexico
facility: Atea Study Site
state: Mexico City
city: Monterrey
country: Mexico
facility: Atea Study Site
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Atea Study Site
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Atea Study Site
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Atea Study Site
state: Nuevo Leon
city: Monterrey
country: Mexico
facility: Atea Study Site
state: Nuevo Leon
city: Querétaro
country: Mexico
facility: Atea Study Site
state: Queretaro
city: Cancún
country: Mexico
facility: Atea Study Site
state: Quintana Roo
city: San Luis Potosí
country: Mexico
facility: Atea Study site
state: San Luis Potos
city: Yucatán
country: Mexico
facility: Atea Study Site
state: Yucatan
city: Chihuahua
country: Mexico
facility: Atea Study Site
city: Oaxaca
country: Mexico
facility: Atea Study Site
city: Puebla
country: Mexico
facility: Atea Study Site
city: Veracruz
country: Mexico
facility: Atea Study Site
city: Veracruz
country: Mexico
facility: Atea Study Site
city: Den Haag
country: Netherlands
facility: Atea Study Site
city: Den Haag
country: Netherlands
facility: Atea Study Site
city: Utrecht
country: Netherlands
facility: Atea Study Site
city: Zwijndrecht
country: Netherlands
facility: Atea Study Site
city: Zwijndrecht
country: Netherlands
facility: Atea Study Site
city: Islamabad
country: Pakistan
facility: Atea Study Site
city: Karachi
country: Pakistan
facility: Atea Study Site
city: Karachi
country: Pakistan
facility: Atea Study Site
city: Lahore
country: Pakistan
facility: Atea Study Site
city: Rawalpindi
country: Pakistan
facility: Atea Study Site
city: Baguio City
country: Philippines
facility: Atea Study Site
state: Cordillera
city: Tacloban City
country: Philippines
facility: Atea Study Site
state: Leyte
city: Ermita
country: Philippines
facility: Atea Study Site
state: Manila
city: San Fernando
country: Philippines
facility: Atea Study Site
state: Pampanga
city: Iloilo City
country: Philippines
facility: Atea Study Site
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country: Philippines
facility: Atea Study Site
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country: Romania
facility: Atea Study Site
city: Bucharest
country: Romania
facility: Atea Study Site
city: Bucuresti
country: Romania
facility: Atea Study Site
city: Bucuresti
country: Romania
facility: Atea Study Site
city: Bucuresti
country: Romania
facility: Atea Study Site
city: Constanţa
country: Romania
facility: Atea Study Site
city: Craiova
country: Romania
facility: Atea Study Site
city: Oradea
country: Romania
facility: Atea Study Site
city: Sibiu
country: Romania
facility: Atea Study Site
city: Suceava
country: Romania
facility: Atea Study Site
city: Timişoara
country: Romania
facility: Atea Study Site
city: East London
country: South Africa
facility: Atea Study Site
state: Eastern Cape
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country: South Africa
facility: Atea Study Site
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city: Pretoria
country: South Africa
facility: Atea Study Site
state: Gauteng
city: Pretoria
country: South Africa
facility: Atea Study Site
state: Gauteng
city: Pretoria
country: South Africa
facility: Atea Study Site
state: Gauteng
city: Randburg
country: South Africa
facility: Atea Study Site
state: Gauteng
city: Thabazimbi
country: South Africa
facility: Atea Study Site
state: Limpopo
city: Kimberley
country: South Africa
facility: Atea Study Site
state: Northern Cape
city: Cape Town
country: South Africa
facility: Atea Study Site
state: Western Cape
city: Plettenberg Bay
country: South Africa
facility: Atea Study Site
state: Western Cape
city: Badalona
country: Spain
facility: Atea Study Site
state: Barcelona
city: Centelles
country: Spain
facility: Atea Study Site
state: Barcelona
city: Marbella
country: Spain
facility: Atea Study Site
state: Malaga
city: Málaga
country: Spain
facility: Atea Study Site
state: Malaga
city: Barcelona
country: Spain
facility: Atea Study Site
city: Madrid
country: Spain
facility: Atea Study Site
city: Solna
country: Sweden
facility: Atea Study Site
city: Umeå
country: Sweden
facility: Atea Study Site
city: La Marsa
country: Tunisia
facility: Atea Study Site
city: Monastir
country: Tunisia
facility: Atea Study Site
city: Montfleury
country: Tunisia
facility: Atea Study Site
city: Sfax
country: Tunisia
facility: Atea Study Site
city: Sousse
country: Tunisia
facility: Atea Study Site
city: Sousse
country: Tunisia
facility: Atea Study Site
city: Tunis
country: Tunisia
facility: Atea Study Site
city: Tunis
country: Tunisia
facility: Atea Study Site
city: Ankara
country: Turkey
facility: Atea Study Site
city: Ankara
country: Turkey
facility: Atea Study Site
city: Ankara
country: Turkey
facility: Atea Study Site
city: Ankara
country: Turkey
facility: Atea Study Site
city: Ankara
country: Turkey
facility: Atea Study Site
city: Antalya
country: Turkey
facility: Atea Study Site
city: Antalya
country: Turkey
facility: Atea Study Site
city: Bursa
country: Turkey
facility: Atea Study Site
city: Denizli
country: Turkey
facility: Atea Study SIte
city: Istanbul
country: Turkey
facility: Atea Study Site
city: Istanbul
country: Turkey
facility: Atea Study Site
city: Istanbul
country: Turkey
facility: Atea Study Site
city: Istanbul
country: Turkey
facility: Atea Study Site
city: Istanbul
country: Turkey
facility: Atea Study Site
city: Istanbul
country: Turkey
facility: Atea Study Site
city: İzmir
country: Turkey
facility: Atea Study Site
city: İzmir
country: Turkey
facility: Atea Study Site
city: İzmir
country: Turkey
facility: Atea Study Site
city: İzmir
country: Turkey
facility: Atea Study Site
city: Kayseri
country: Turkey
facility: Atea Study SIte
city: Samsun
country: Turkey
facility: Atea Study Site
city: Yenimahalle
country: Turkey
facility: Atea Study Site
city: Exeter
country: United Kingdom
facility: Atea Study Site
state: Devon
city: Plymouth
country: United Kingdom
facility: Atea Study Site
state: Devon
city: London
country: United Kingdom
facility: Atea Study Site
state: Greater London
city: London
country: United Kingdom
facility: Atea Study Site
state: Greater London
city: Castleford
country: United Kingdom
facility: Atea Study Site
state: West Yourkshire
Study officials:
References: