Clinical trial NCT05947227: Effects of BBT Versus Diaphragmatic Breathing on Exercise Capacity and Quality of Life in Patients With COPD
Official title: Effects of BBT Versus Diaphragmatic Breathing on Exercise Capacity and Quality of Life in Patients With COPD
Study type: INTERVENTIONAL
Overall status: COMPLETED
Phase: NA
Conditions: Breathing Technique
Keywords: Chronic obstructive pulmonary disease/COPD
Diaphragmatic breathing technique
Lead sponsor: Riphah International University
Sponsor class: OTHER
First posted: 2023-07-17
Enrollment: 48
Sex: ALL
Minimum age (years): 40
Maximum age (years): 65
Standard ages: ADULT
OLDER_ADULT
Accepts healthy volunteers: no
Allocation: RANDOMIZED
Intervention model: PARALLEL
Intervention model description: Group A will be treated with manual chest physical therapy and Buteyko breathing technique Group-B will be treated with manual chest physical therapy and Diaphragmatic breathing technique. Patients will perform the technique 5 times a weeks for 8weeks and treatment evaluation will be done after 8 weeks.
Primary purpose: TREATMENT

Brief summary: Group A will be treated with manual chest physical therapy and Buteyko breathing technique Group-B will be treated with manual chest physical therapy and Diaphragmatic breathing technique. Patients will perform the technique 5 times a weeks for 8weeks and treatment evaluation will be done after 8 weeks

Detailed description: A randomized clinical trial will be conducted at Gulab Devi Hospital, Lahore through convenience sampling technique on 48 patients which will be allocated through simple random sampling through sealed enveloped into group A and group B. Pre-treatment values of patients exercise capacity will be recorded by 6MWT/6MWD- 6 minute walk test/ 6 minutes' walk distance and patients quality of life through St George respiratory questionnaire as primary outcomes while oxygen saturation, heart rate will be measured by pulse oximtery during 6MWT as secondary outcomes. Group A will be treated with manual chest physical therapy and Buteyko breathing technique Group-B will be treated with manual chest physical therapy and Diaphragmatic breathing technique. Patients will perform the technique 5 times a weeks for 8weeks and treatment evaluation will be done after 8 weeks.

Data will be analyzed using SPSS software version 25.After assessing normality of data by Shapiro-Wilk test , it will be decidedeither parametric or non-parametric test will be used.

Eligibility criteria: Inclusion Criteria:

* Age group : 40-65 years
* Both males and females
* Clinical diagnosis of COPD confirmed by smoking history and PFT airflow
* Patients taking their regular medications e.g bronchodilator

Exclusion Criteria:

* Restrictive lung disease
* Pneumothorax
* Resting O2 saturation \<90% with room air breathing
* Recent exacerbations
* Patients with active viral or bacterial infection
* Abdominal or thoracic surgery (\<3months ago)
* Cardiologic conditions (\<6months ago e.g Myocardial infarction or unstable angina
* Intubated Patients
* Orthopedic or urogenital conditions
* Neurological disorders limiting cognition \& mobility

Primary outcomes:
measure: 6 Minute Walk Distance
timeFrame: 4 weeks.
Secondary outcomes:
measure: St George Respiratory Questionnaire for quality of life :
timeFrame: 4 weeks.
Other outcomes:
measure: oxygen saturation
timeFrame: 4 weeks
measure: heart rate
timeFrame: 4 weeks
Locations:
city: Lahore
country: Pakistan
facility: Gulab Devi Hospital, Lahore
state: Punjab
Study officials:
affiliation: Riphah International University
name: Sidra Faisal, MS.CPPT
role: PRINCIPAL_INVESTIGATOR
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citation: Vogelmeier CF, Criner GJ, Martinez FJ, Anzueto A, Barnes PJ, Bourbeau J, Celli BR, Chen R, Decramer M, Fabbri LM, Frith P, Halpin DM, Lopez Varela MV, Nishimura M, Roche N, Rodriguez-Roisin R, Sin DD, Singh D, Stockley R, Vestbo J, Wedzicha JA, Agusti A. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report. GOLD Executive Summary. Am J Respir Crit Care Med. 2017 Mar 1;195(5):557-582. doi: 10.1164/rccm.201701-0218PP.